<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="https://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT43</accession>
    <name>A0AAD5TT43_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002376</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001784">
        <property type="protein sequence ID" value="KAJ3201093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT43"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF28">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3201093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="58292" checksum="52AFC3AFE89A0122" modified="2024-05-29" version="1" fragment="single">TSKIHRPNIVKEKTEKEISNEEITTSSNLKKKINETQFKINNEQGELHGRGFFQKLARKDEETRLMQVTKHYSRLSGFDKIQFLSRLQYKRFIPESILVYKKLFENNVIARAKYHHHHNLIHLCIQNPGKYEDGIISAWEAMNKLNIEPSNNLLADMIYCASKWKNFELGNLWFEKLRGRMNANDVQIKTYNEILYICATVGGMKNDDSILNAGMKIWQDMIENLPHSEFDFNTYSYSLSIHSMLGNIDELEKLIELEDKNFENIFQWYKIVNQDKVNKNQESKISLEEKLRLKITTNQIQWLSKCKLKNNKLDTEENKKVLKLILKKYTYLIQTPNLEPNLLSFYFIFQFLSKTNNYEVFVKFVKELENFDNLSLTFSFYSQLVLIYFKFGKVDQALNIYEKMKTKFGHLKTFNRAKLTLLKGYSSVGDLQNCLKVFKDIKSSYNDATEKNNKDSSSVLKGSYLTLIDCYKSKGKLYDLSSIVIVVDSWLKKNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT62</accession>
    <name>A0AAD5TT62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001678">
        <property type="protein sequence ID" value="KAJ3201748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT62"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3201748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="21896" checksum="3F575BDCF75328C0" modified="2024-05-29" version="1" fragment="single">MRDNQNSLVGVLNHDWWKQVYSKFQLTDDNQVYPNSQVPKEKQIFSKSKLTTNELYPKQLSNNELYPNLLINYGQENTHNNDTMNKTQERNSTLKNSPTTSVTSELLKTRQSPTEFESEESTINLLKQAINVTEKNLNLLKENVNRLKRSDAALVANKIRCKHKRIRCRECHGFGCPHGRQRSRCKEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTE6</accession>
    <name>A0AAD5TTE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001534">
        <property type="protein sequence ID" value="KAJ3202686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTE6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3202686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="565" mass="65141" checksum="77393ECB99D863F5" modified="2024-05-29" version="1" fragment="single">CDRIFEHESETYEHCLEAHSISGKQLCQWTSNSNFGSCGHKYHFSVDFRPLQCHVCLKRIRSRQELNRHSKTHTKLKRNSKFPEDNISSSSSEVIVDDFKNKFDDMETTTSINNDEINNSTIDKGNVYENHLVIGNDYVEKSGSSVELFNLVKDYSLSTTSSECSTSDSSSPYDAFSNISTDSYQKLTDLTQYLMSENFLLSLMQFNNTASSSSSPARFPQLIPNVENHIFNDDPMNTTEFSMEKKNSNTDFDPFELKLEELKNSLSHLTLDHLRINLTNPCHVGTNLGMFWINFKAILEKFQINVPEGIKTTLVARYLKDGAMGRITHQTRQDISDVLLSDPNYNFSKCIEFAKIVVPENLWLIYQPFITKITKELIATIKVIFKEGLQVQSINSNTFLSFQQPNYNPNYPYRRLLITIVKVVKSNLEVYLSNEDKLLFFQPNDKSSLFRPPSDCTASAILLHYKFAFPAVSTYEKTFLESLRNVTQMGIDELVKKMIFGEEKFGEICRKTCCFGFLCTGIVRFNWDFFGFENESYLWMRLGNDEQFVFKLIEDLNTNIEPILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTG4</accession>
    <name>A0AAD5TTG4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_001704</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010001508">
        <property type="protein sequence ID" value="KAJ3202887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTG4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050582">
        <property type="entry name" value="HAD-like_SerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344:SF2">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="430"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR604469-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3202887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="590" mass="65963" checksum="7EEE7A5F103FAEB5" modified="2024-05-29" version="1" fragment="single">FLLEKKEKYPENFSTKFIDYQSLKTYIKEEIKPNDLSNLTTNNSTDFKKQVKSKLNKLEEKIFEFFNLIEIEVNNLEKVYQLELNSVELKFQLFFDNFLKKEKSASVNSDDNYLTFQNFLKDVVRLERFILLNYTGLKIGAQFIMTLTDLNFFKSVKLSNLKKQLIELVTVNNGSELVNSGTSTPTAVTLSKKNNGSSIFNTTLVEQSLNSLSLSIPASLTSSEQSSFPPPNSLLPNQKILISMNGPHGTDIIGAVLQCVSKYNLPVEDFVLSRLYHNVTFGCLTKINNESVQIFQDLNVLAKKWESSLFYDSYSDSDKVFNSLEDAPYQDRVKYTATVLNQVGLSSEFLFDFTRLLLDYKISVEKMFKLSGLQKGEMLCSADFKLSVPLNVDFDQFRADLFNLSGKHGTDVALQPNDVFRKSKRLVIFDMDSTLIQQEVIDEIAKHAGVVGEVAKITEAAMNGEIDFKESLKQRVALLKGTSVNVLEIVKEKLTFTEGAHSLCKALKKLGYKLAVISGGFMPLALHVKNHLVSTDGKTLTGETIGPIVDGMRKAELLDVIAQAESVSSEQVIAVGDGANDLWMLAAAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTL0</accession>
    <name>A0AAD5TTL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001545">
        <property type="protein sequence ID" value="KAJ3202613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTL0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="151" mass="17259" checksum="058A615AE01E291B" modified="2024-05-29" version="1" fragment="single">MQDTNTEKEESLSSPIKKNSFFSSSEELEAISSDEEGIEGDDEIYSSKVTKRSPKRTHFKHHEEKKSNSAVPSDLKVNEDSFQKKFINLFLLPFCQGVFYGLGEGVARKTLHNYWDLRYSTRSEVVLASCSSIFFSKFLSLNDTFSNFSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTR3</accession>
    <name>A0AAD5TTR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001570">
        <property type="protein sequence ID" value="KAJ3202443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3202443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="447" mass="52223" checksum="37A0DC2631C3F355" modified="2024-05-29" version="1">MTTTSCKWLNCNHIPFSSELDCYNHIKTQHTKSGPQRCRWIIEKSFEPPTSTSFPSITNSHAAINLCNIMSKHRGHFIEHCVSHFSFNLRPLKCTYCGETFRNRQEFKRHEKLNHPDETSKYNCFDNSDEKSDNNNNTHYKDTQLENNQNFHTANQVDYSEIDSNSRHLLSPPYSNIGVVPAFFKSYCNVLRDYGLILPRNISHLIDDVCQQGGRIPPVIETELIEELLSSCQISIPGLCFFYNEAGNVLLMESLIKEFSENSKSIWEKYDIKQKKILLKNSVEKKFEECRIALKKTLISLLQLFWKIFASKITNEDNGQLVDSSCNLNEIYSVGLLITINHQLEVNSLSNRKNLYLNCVNFLKKEIEEGLLKRNCRRKTNDKKLEKEQVLEEDEEEVKIFFNCKSIDFFAPEILIWFKFGLNKNEVEMKFESYFRNSFLTFLGFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTY4</accession>
    <name>A0AAD5TTY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001881</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001583">
        <property type="protein sequence ID" value="KAJ3202356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03188">
        <property type="entry name" value="GST_C_Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03057">
        <property type="entry name" value="GST_N_Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="96"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3202356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="23252" checksum="D731A1E7B3C44DA5" modified="2024-05-29" version="1">MSATLYFTTTSCGAASFIAAHKAGVIGSKVVPVIADIKKKLVLTGSNKGSDFFKVNPKGNVPALVLSDGKLLNENAATLQYIADLNPAAKLAPANGTNERYVLQSKLSFLSSEVHSSVGSLFSAPAGDIREYFVQKANTKLSYLEKVELPGKKFLVGDNFTVADSYLYIILSWLQFLNIDLATYPVLKSYYENIASLDFVKEAHAKMAEIAKEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUB0</accession>
    <name>A0AAD5TUB0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sorting nexin/Vps5-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001418">
        <property type="protein sequence ID" value="KAJ3203516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUB0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sorting nexin/Vps5-like C-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="114" mass="13359" checksum="2B4E6E1A72E95157" modified="2024-05-29" version="1">MGESLSQFSSIEINSNVQNKYLKFGEILKEMQPLMEKQGKIDLNHLINCTEEWIRTIGSIRAQKQVSKEKKDFEIISETLLKEFDRLEEEVCLDFTNSIKLFVKGFVKTQKEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUB3</accession>
    <name>A0AAD5TUB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import receptor subunit TOM20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_003460</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002268">
        <property type="protein sequence ID" value="KAJ3198772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUB3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016031">
        <property type="term" value="P:tRNA import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.10">
        <property type="entry name" value="Mitochondrial outer membrane translocase complex, subunit Tom20 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002056">
        <property type="entry name" value="MAS20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023392">
        <property type="entry name" value="Tom20_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12430">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12430:SF0">
        <property type="entry name" value="TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02064">
        <property type="entry name" value="MAS20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037707">
        <property type="entry name" value="MAS20_rcpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47157">
        <property type="entry name" value="Mitochondrial import receptor subunit Tom20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3198772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="18208" checksum="F62D7C842BAA7058" modified="2024-05-29" version="1" fragment="single">IYGVGLGLGVLSIAYLIYFDQKRRNDSNFRRRIKRERKISEKNTQEKALEKKAAQLAAAKRAQAFTGAGRNHDQLIEELEKEPLPQTQKEKEEYFMKHLEAGEKLLALGPTYQQAAADCFFRVLNIYPDPMQLLAVLESSIPQEVFQLVMAKMVADVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUT3</accession>
    <name>A0AAD5TUT3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">FKBP12-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FAP1</name>
        <name evidence="11" type="ORF">HK099_000342</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001077">
        <property type="protein sequence ID" value="KAJ3207137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUT3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034078">
        <property type="entry name" value="NFX1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360:SF12">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR NF-X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="NF-X1-type" evidence="10">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="NF-X1-type" evidence="10">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3207137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="512" mass="57865" checksum="29AFD7030F41A685" modified="2024-05-29" version="1">MLGCGHPGKCHDCLDGVSFEELSCNCGKTKMYPPIPCNLEDDEPCPPCMIFTERKCACEKKEMKNIPCSSLRSPSCGLMCEKLIEGCGHNCKRFCHVGECVDAVHSCQERCRRTRAICGHRCKYFCHGTSFCTEEKPCLAVVTSTCACGRRKVEQKCGADKENLGISKVELPCDEGCAVMERNKRLAEAFDKVEDDEIVSSELDYSESLAKFAHTKPEECKNVEEKLATFVAAVATNPIDYKILSSRTESNKIIAGWDASGVVEAVDQTKNYFYFPKSKMKKSLFISELATQHYNLNAEILDANIGMANVVVRKGVGKKGQIPALLLSEVAVNYSPQLYENINLHKQNNQLSHTEIIENSKENNFNGIFLRNISFGIEVNDLKILLEPFFHTNFIPSLKKIKNVCKEDCFIILFNTNKQDPNQNFEKDLKNFYKIVEKKFCIDNNFASSCNLCFVDCEGRVNLKDDFGEELYKKEEILSTNNLQKKNSFNNENLKNSTLENSFNKFNILDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV73</accession>
    <name>A0AAD5TV73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001677">
        <property type="protein sequence ID" value="KAJ3201758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV73"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="237" mass="27864" checksum="28D375C3C37150E6" modified="2024-05-29" version="1" fragment="single">RIPQQFEILKSNLPHLEKAQKFLNLPLPKYFGELNLSNNLKYTISILSNFVQANQQVLEHFAEGVLWCNPAQFIPLFEEVKIVNHKALEILKDIQQKYPIQVLLVKTISVSQFLLRLKKEYLTLKYENGFLDDKVYDEVFFYLDFRHNRLQKENPVIFKREFKFTEKTDSDVTKNHLLEKELENIEENLNELKKLKQSKIERSSSDQQKFNVLPDNTTDLEKSINISDLKNSAGSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVE8</accession>
    <name>A0AAD5TVE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002173">
        <property type="protein sequence ID" value="KAJ3199172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVE8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036286">
        <property type="term" value="C:eisosome filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070941">
        <property type="term" value="P:eisosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028245">
        <property type="entry name" value="PIL1/LSP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962">
        <property type="entry name" value="SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962:SF1">
        <property type="entry name" value="SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13805">
        <property type="entry name" value="Pil1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="129" mass="15091" checksum="074041366C7747B0" modified="2024-05-29" version="1">MKVWGKKEDPDLADITEKLELLMGGVSESFNKISSKNESFRKVIKELRASDEQLCQQKIKVKSLEQQIEQQTKKLKPTNQLKSELVQVENQLCQMEAQNYNLKRKKLKSALFDKFDALKEFSETVFLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVG5</accession>
    <name>A0AAD5TVG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Anoctamin-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ANO7_1</name>
        <name evidence="11" type="ORF">HK099_000310</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001067">
        <property type="protein sequence ID" value="KAJ3207271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVG5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032394">
        <property type="entry name" value="Anoct_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16178">
        <property type="entry name" value="Anoct_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="719"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="768"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="957"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1007"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1049"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin dimerisation" evidence="10">
        <location>
            <begin position="487"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="9">
        <location>
            <begin position="709"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="9">
        <location>
            <begin position="821"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="244"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="358"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="36"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="387"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3207271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1104" mass="127863" checksum="651B9C72988B9749" modified="2024-05-29" version="1" fragment="single">EEEDEEEEEEFNEDEQNDDFNGSGQQNNLQQSFLNSKEDSLIISKKESLVSIKKPVEKELKQDDLKMESNLKRKSSKKKKHRRDFIQQDEEEEVTKSRSHRRHQHHQHHHKKPLTKHQSRSGSETEIEKNKQQGGFKKQEKIYLSNSSTGNGVKKVQEWIQSNENFINANADGNVYDNHDHNAENAEKSNFEFVSNTGIFNNSGKDQPVNDNHNSLQHSLNQLNQCGNQGLNDKENGQQFNKTNIHQENNNNNHIENKNKNDIENNNNNDIGSYPNVNGSAENELFYEQEDHQDLGESKNIGNLIDGSEQEDIVDDHHAKDRKLVLSKDAHKNFQQPSPSQRLLPPISALKLNLPKDAIDYSNRSRSRQEEESRNDRRKSYKGVSLASITQQQPWGTSLKNVPKKNNNGGSVRNSASLHEDNYHANNSINQQKSFLDEDGNDNEIRRNLNYNLQKDVLEQGNWNDDECNGILKNEVTRRSIGSRHFVLWYAEDVELFDNILLWKNENSKASVEAALSKFGNISSFLLELEVSMENPNNVFIKILSPFHLLCKTAHAEKLRLPLKKQNLPISTTIINKLAPSSFAKFFNVEEFVDLNQQTGQFSIENFQQFKGVEPNTPVGIIQKNFFKPFHRSLLTRKAIEAIKIKIVGRPIAQYLGITYFLSENIYTKFYYPHDQFRDVETLRGISLREHLKKEWLSKCTLHQPLDHIRDYFGEKLTFYFAFGSYYTCWLIIYAIFGLIVTFYGIYDIRNNGAEDKWAWRRLYDNKLMPYFSFFTSFWVVVFLEFWKRKTNYLAFEWGLSNFENEESIRANFTPTTNKMGVSFFNIYARLFYYTFSKPFFLNLNDYGCLVNCTTEVLAQVGGVFLGDIVFGVISEIIAPLLSKNREDSKANKNIIFPHPNTLSPYGVSASTSSLLTNGDQKNSTILPLTSPHVVDNNLPEITDELELDYLQKITQYSILVMFSVIFPPAPFIAFIGQCFQNRSDGYKYLFLYKRIQPSQAQDIGRWYEILSFISVLAVTVNVLLVVYLSNSFEETYLTRYENSNWPSIRLGIVIVWHIAIYIFKYLISFCIPDIPKMVKIAKAREAYLEKIVILGDNEYDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVK7</accession>
    <name>A0AAD5TVK7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001550</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001448">
        <property type="protein sequence ID" value="KAJ3203294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVK7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="345"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3203294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="46277" checksum="F1285123F099DC84" modified="2024-05-29" version="1">MVSKWKYDPNQSKYKKVEKFIDIFDHLGDIYRTHHRLGKGSYAEVFKVSLVNSSGNEHYALKKTHEDADAIRPGICQSTLREINIMQELDNINIMSLNKIYRFHSSQNIFMEMDIASYDLQTLIGNESKHFPIPHADVKTQTLLYRSPEVVLMREKSDGMANYFCEIDMWSCGLIVAELLKGRTLLNPDLCKNEVGLINEFKRIIGFPARNSEIFPDHLYSMDNGYESVNFELTIFENRADDDTRLKKEALSFMRRMIQFDPVKRVKTFEAILDKYLEDQFDAPALKQIYRDNLQALDRKFYMKRNLMIEDLTVTSKELKETKLEGRDSCYGSEVNNVNMEIENTDPSKTNFSPCSSPKYHKSNNSISNVKPSRHSTIPTPPNELAESGVKGIINRFSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVU4</accession>
    <name>A0AAD5TVU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyltransferase family 28 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008631</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000970">
        <property type="protein sequence ID" value="KAJ3208896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVU4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000268">
        <property type="entry name" value="Glycosyltransferase family 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="2">
        <location>
            <begin position="253"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="3">
        <location>
            <begin position="509"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3208896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="794" mass="88388" checksum="0BE538FB5A9039F1" modified="2024-05-29" version="1">MPNQPPSDTHHIDANVVDIQSDHVPPLPPRPTNRCFVGYSELTEILNELMIFGKYFQSNQLHLRIEHLPRGCNDFIDFWLLENPSHQIVYVGESTVSSMDSQDFCLQLDKQTHEGFMGAFLELMVNEGQIWKTKISKSSDYSTDQNETDKNVTKRGNEKYVKNLLKEQVISRPETSVTASTISLNKSLKYEASFKKGKLKIDVDEKNFHLLEDDRKSIFFEETFNEKKFLENIKQVELFKYEHSKTIVPFLNILILIVGSRGDVQPFVALGKELLKYGHRVRLATHETFRNFVNENGLEFYPLAGDPAELMAYMVKNPGLIPGMESVKNGEIGKKKEFMAEVLKTSWSACIEPDDRTGKEFIAQAIIANPPSFAHIHCAEKLSIPLHIYFTTKTLDLPSLSATVGPLLLHELEIPHTYCWSPNLIKKPGDWGEHIDISGFFFLDLATNYTPPQDLQDFLNAGPAPVYIGFGSIVVDDPDGLTKIIFAAVKKAGLRAIVSKGWGGLGGEDIPSNIFMIGNCPHDWLFEQVSAVIHHGGAGTTAAGLLKGKPTGVVPFFGDQPFWGAMIHRMKVGPAPIPHKSLNEENLSAALKILTLEETKKNAFELGKVMKTENGVDVGVKSFHRHLPISLMKCDLQPTKVAEYFLKGANLKLSGSSAEVLIEKGRIALKDLIEYKYKTYDYLTEHNDIISGAIGGSYSMATDYFKGLSKLYTQTAKGIKKAQSTDSHTRATYEITKGVAMGVGNSLYFPLRGVGKFLGQLGDGARNTTAFIDSTELKKEKKKVDGVGQGLKYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW55</accession>
    <name>A0AAD5TW55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001718">
        <property type="protein sequence ID" value="KAJ3201492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW55"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="340" mass="38504" checksum="351575BA17DD16EF" modified="2024-05-29" version="1" fragment="single">MEKEEVSTTTRMGENLDESSLKNKTKNLESVKSESSISGPMSALNLKSNLSEITLIDELEEKESLGDDDSLKNKQKFENENYEDKLKICKGGRHLYKRKNSRKRPISNVDSDLVKTDNLSANESKKDLIKDDLQKPKEKKEKLPNTQKLTSKKKNVTVNKIKSTNNPPKSQALMVNSSIPQQVFPFFFQRQAFPNTKNTSLQPSNEGNEKKNAVSTDNKEQPAFFPFNPTFLNSTLNANHAQFPFFVPQLVNGKNEDGDEESKETNTDKKNLDTVDTKVEKEEIEKSIQEKIIASQQPIMIPIPPWLLMHRQPSSTAFIPVNHVIGDIGWQEMHDAASTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW73</accession>
    <name>A0AAD5TW73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">HK099_008222</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000885">
        <property type="protein sequence ID" value="KAJ3210542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015662">
        <property type="term" value="F:P-type ion transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000056">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10880">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057255">
        <property type="entry name" value="2TM_P5A-ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036075">
        <property type="entry name" value="ARMT-1-like_metal-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002791">
        <property type="entry name" value="ARMT1-like_metal-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF7">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23143">
        <property type="entry name" value="2TM_P5A-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01937">
        <property type="entry name" value="ARMT1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111321">
        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="975"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1000"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1037"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="domain" description="P5A-ATPase transmembrane helical hairpin" evidence="18">
        <location>
            <begin position="32"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="16">
        <location>
            <begin position="255"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Damage-control phosphatase ARMT1-like metal-binding" evidence="17">
        <location>
            <begin position="1169"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="892"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF23143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3210542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1616" mass="184721" checksum="A4749A1AE2080646" modified="2024-05-29" version="1">MEKSTVKPKEKKYLQNLIASKSIKSATLHNKKPLLQHWYALPFSPVYVVWLYCYFFKMKEVSSELTTFSFIVVFAVNAIVYLSTHWAVSAKALLTCNVETDPYKASLIKIIPIEHNGQGEFCELKKHRVIYKEKEVLELFFFFQKRKFVYNSSSKLFEKLTYPSKQGLALKEFKYSLGFDIPIPTFGALFKEQAVAPFFIFQLFCVSLWFLDDMMYYSLFTVFMLIVFESTMVFQRLKNLQEFRAMSIKPYPIYVYRCLKWTLVQTDELVPGDVCSVVRSADEDGSPVPCDMLVLQGSGIVNEAMLSGESTPQLKESIWHKEDDNKFDIESDKGSVLFAGTKVLQVTSPKYEKTDPEEILFVNQKLPKAPDNGCISYVLRTGFSTQQGKLVRMIIFSTERITANNLESLLFILFLMFFALIAAGYVWVEGVNNPKRKQSKVLLDCILIVTSVVPPELPMELSLAVNNSLIALAKGYVFCTEPFRIPFAGKIDVACFDKTGTLTVEDLIVEGVVGKVDAKEIENTLVVSDKVEKETAYVLASAHSLVFLTDVGDSSNTIIGDPMEKNTLESINWTLIKGDLVFPKKFEGSFKPSNNLKILRRFAFSSSLKRMSTICSVTEENKLHSKLFVSVKGAPETIEKMLCNVPKRYSETYKYWSRRGSRVLALAFKYIDEKPSRVHDLKRDDIESLLTFAGFLVFSCPLKPDSAKAIKELNNSSHRVVMITGDNALTASHVAKEVEIVKRNVLIGDVWDEEVGFEWRTVEEDVKFKIDPTSNIMDERLAKYDLCITGRGFAEVFEQECWYAYLLPRIWVYARVSPSQKESILTSLKQAGYHSLMCGDGTNDVGALKQSHVGIALLDGNVADLERLAKKQSIQRQQNMLEQQKKLRESWGIKEGKPGESTGNSALDKRRQQEEVMKQKLASMMEDMGDVPMLKFGDASVAAPFTSKLSSINSVLHIVRQGRSTLVAMIQMYKILALNCLISAYSMSVMYLAGIKQGDWQATIAGLMITVCFFGIAKSTAIETLSKKRPQSNVFNFYIMISVMGQAAIHVLSMSYIRYEAIRYSEEMEEEFDLDSAFQPNLLNSAVYLVNLIMQISTFAINYQGLPFRESLQQNKSLYYSLGGTSAIAILAATEWSPELNEWMQLVPFPEEHAKSFLTGKNNEFAFKTIKDRMPIILTKAINELHLALTNLIDVKEEEDKLKEGKIILNALSGLKYDLEHDTVLEPIDSRSEDHGLWNIYLEQMPYGENTWFTAPWLTSECYMYKRINVLFETSTYWKEYDIFETLKKQSYMDSVNSVKLILDNFYTAENFKKFSDNENFKNLFDELIQFSLWGNQSDLSLNVSSEQQNASNKNQKTNSDHLLSHSENLILNDLEKVKNFFKFDELHKETKKGLKVDIILDNAGFELFTDLLFADFLIKSHIASQVTFHVKHFPWFVSDATRNDFEYLLKEIKKIKDESKGNLCNLDWEDNLKSKKWILKYEDGVWNLPHSYWDLENFLTFNNDSECYFIGKCWKEISAESDLVIMKGDLHYRKLTRDYGGHHDIPLEDVLGPLGEKTQHRTPPILCLRTCKSHPQTGLREGQSEELDKIDPDWRINGKFGIVQFYEGLSAETLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWD3</accession>
    <name>A0AAD5TWD3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyltransferase family 69 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001395">
        <property type="protein sequence ID" value="KAJ3203675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWD3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021047">
        <property type="entry name" value="Mannosyltransferase_CMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34144:SF7">
        <property type="entry name" value="EXPORT PROTEIN (CAP59), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11735">
        <property type="entry name" value="CAP59_mtransfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="38231" checksum="564C7BDDC04A03A4" modified="2024-05-29" version="1">MITFSIKDHVREMNTQNFDLQQSIYIAANLYNSEKILPTFTKNLIQISKLFLSANKYNRVFISIFENGSTDHTKTLLLNFKKELEKLNIPHNIRISEDPKAFFRRIPYLAKVRNEVLNDLGSFRYDKVLFLNDIIFKIEDVLKLLSLKDTDAVCGLDFTYRFYDIMVTRDNVTFPYPVSGVPPYFFDPVKWKLFKKNKLIPVFSCWNGLVVFKSDIFEKIKFRSLHPLKTNLGYEASECCLIFSDMHKFNRTRIFIDPTVKITYNTPTWLESIVFYFDKYFLYYFNYPKIPKEGSKEFNNFELMKKLAIVDGLENEFDLACVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWD8</accession>
    <name>A0AAD5TWD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001585">
        <property type="protein sequence ID" value="KAJ3202344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWD8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="126" mass="14283" checksum="379CC412F02E36C2" modified="2024-05-29" version="1" fragment="single">MSNKTAFVLYSLTPSALKPQAPILCFAWGVATLIAIQLTIRNLFNNRRSWIDVVQFLAGISLIVQELISFGKMYNLTAPVTPDCDYVNYTRFLSFILFQIFANLVLILRITVLVPKNFQLAVRVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWW5</accession>
    <name>A0AAD5TWW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000712">
        <property type="protein sequence ID" value="KAJ3213433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052819">
        <property type="entry name" value="Chromatin_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="385"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="7">
        <location>
            <begin position="962"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="926"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="926"/>
            <end position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3213433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1095" mass="125587" checksum="E6B670B35334F348" modified="2024-05-29" version="1">MVGDLHVKNFQKLDKSPQKLNNVIGEEKSKSGIKAKENQINSKNKVKQNETIEISNDHTTTNLNTNFNQNKDANALNFPIEKKIGKIKINFKNSLVEQQNDRSKNNSNNDNININTASSISSTNISSNNFNNTNDLRRRKSSILKLFSTKNDNEDGYASDSTLSSVESIPSRTMSPKLKEAEDNTLFEDNEDLSSVCSTPVEQSSPQSVRKRELRSRTTSNNHLFTPISKDEKSIKNKKDRDGKSENSAKRKNKNRGMTTKLGGKGDDEEVTSGGKSSFTKVHVPAGLVNPFDLMESRNREKSRYHTGKVIYKIEAQSVENFRRILETEISSDLDLIRNGLVEFGSNYTNGINTRSNTTNKNTALSDTPGSPLKIEDIKKNMANDDFCSACLQKGKLICCDSCPRTFHICCLEEGYDIPSSGLWFCRECSNRGQKKVKVNNIFFDPLLNHMRGMNPRVFELSQDIREMYENVWTHPGTGDFIDVNNCEVVNINNKTRSVKNNIGVIENFPIKIKEKFKCCYSCGKSDIKQCQNSLLNSFSVGFDLSKKSKDVIPRAERSEMIKCDYCNLHWHLDCLDPPLPNIPWEFKEEKEIVDTNFIKKLRKRAWGEVDEEEDELKKAKKFAPESLNSYFVGLIQIRKKWMCPLHVENILNISKRIKRSTKVVDAPINSNSKSNTSSPSISKKHLITSKIGEIGNLKKRKFLDFENSKQQKINDQVEARIGNFEEKIINEVTYKLPEYKVKLDFFSKVDEKKKKKQNIIKEDLSFPIGLGLEYTNKLKELYYDNDNGGINFDNNKNEEKMNKNLLLVASEIIEKEQSNLNKFNAKFNNFNVNNINGNNNSNSNLNIFENGLRCTDEEADLWLESVSQMQMDIANRIIEQINKKNIAKGLVNEMENEKKVMHNSDEENDEILKGIEKIRNDNEEEKKNKTIVESNLEEKTNNNDDTSSTLKKKKKKIKNELPEDSVWQKLQDPNTSKYYYFNSITQETTWISPMDPDFIEKKKKEKMDNLQQNQKLQQQQQWGGYTDLSQQQPYFGNDITYQYNNGEAPPGLENEVSNQQNTQQQPTYEDYTVTGAFNTSTGRFQVNDVRGNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX13</accession>
    <name>A0AAD5TX13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002188">
        <property type="protein sequence ID" value="KAJ3199105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX13"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="296" mass="34201" checksum="04A3AB8DC527DE87" modified="2024-05-29" version="1" fragment="single">NAAIAEYSTTELVEVLERLESSRRLTGSQSNITAMQSNSKFFERSKFQNQYDTWELEDLFSFVDKDDEGELKFLIQKSVSAYYDKADGTLKMDHILSNRVTTDLMILSTVEIKKNQEPAKTFLSTLDVNTRTILESFVLKLEAVQAEMHVSSDNRNHFLETVTGKRSLNQLVSIIHNLHFSIMKRQLHPYQYFFSESIHCLYLMCKCIKVTSTNEGAAQPRYFAKFDTDFTNKIAILQHLMRMTVVFEIYHEITLNNQDIQYRFLLSLVNTEFEGTNGVSKTSFSLLQELMKLATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXL2</accession>
    <name>A0AAD5TXL2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome biogenesis protein NOP53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_006669</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NOP53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000591">
        <property type="protein sequence ID" value="KAJ3214793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXL2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011687">
        <property type="entry name" value="Nop53/GLTSCR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211">
        <property type="entry name" value="GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211:SF7">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07767">
        <property type="entry name" value="Nop53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3214793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="152" mass="17663" checksum="43D171322D18B294" modified="2024-05-29" version="1">MEEDDNNFAKVVLSESRKTRAQRNKEQRKIAKEREEKKIKDAKELALQVSNIKEINNAVNSTLNMEKSVTVKESSQMRLGPHKFKSIPKALDVTLTEDLADSLRIIKPEGNIFTERFNSLQERGLIEPRVPVGKKRKFKKKVIEVHSYKRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXS2</accession>
    <name>A0AAD5TXS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mismatch repair protein msh3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MSH3</name>
        <name evidence="5" type="ORF">HK099_006887</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000623">
        <property type="protein sequence ID" value="KAJ3214402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXS2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF34">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="4">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3214402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="123" mass="13984" checksum="2233632F9F35FF89" modified="2024-05-29" version="1" fragment="single">ILLDEVGRGTSTEEAISLSFAILEHIVNEMKCRTLFATHYKQLLKIINEKKKLEPNSLNGIEFFKTEVKICEGEAIYSYKFVKGVANDSHGIFVAERAGIDKKITNRAKFILSEIKDRKCLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXT6</accession>
    <name>A0AAD5TXT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006964</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000639">
        <property type="protein sequence ID" value="KAJ3214224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXT6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027948">
        <property type="entry name" value="DUF4436"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14494">
        <property type="entry name" value="DUF4436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3214224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="481" mass="53139" checksum="3A9D57E31A4BF356" modified="2024-05-29" version="1">MTQVATIETDFLTDISQGNFNLVLDAINNKPLIIDEKLPTGESALWLAIERDDEKLIKLLLEGSGCDVNLPNHVGATPLFVSCEIGNEKIAEWLLESTADPNLVLKGDESSPRNYIAAENACFESLEILIKNGADINLAGKDHATPLFISSNCNFPRIVEFLLKNGADPDKKFCGITSPLYNAAQKASNPEVDAIVIVARLSQFDIIKFTYIVHFEFLISGPTLTNRGYLENAVTINFGSQSKLFPRAVQMQSQDLTFTFTEGDSNNYPLDEFIDAFTISASYADIRVNNSNTPPPIVVEALGSLQGYTIEYGVAESEEIPYSTGFALKLTRSNTTKFFSFLMILTMWCLSASVLILAITLWMRDRKVEPPTIGVTTGLLFALPAIRNVQPGIPGIGCTADVVGLFWNITMVAVASLLLLVNYIKKYKKEKTSLPFTTDQLYIAKQEDIKKSEDASYRESLIFNDEEVQSNKVGDFVNVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY09</accession>
    <name>A0AAD5TY09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-like protein arp8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ARP8</name>
        <name evidence="3" type="ORF">HK099_006380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000545">
        <property type="protein sequence ID" value="KAJ3215412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY09"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10206">
        <property type="entry name" value="ASKHA_NBD_Arp8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17003">
        <property type="entry name" value="Actin_micro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="622" mass="71320" checksum="B275C276C6FC4D75" modified="2024-05-29" version="1">MGKVKRFTSIPKLQNLLSTKSSNVAIKSKRDVNHGNSLTPAQSEIKNETSSLVTKEPKETLILHFGSSYLRVGKATDSFPKQFPCLLARKVKLQNSQDDLEDYNIFNYSIENKSKLDKIVKDRISLKKIKVLPNPQAQVVNFNQNSEYISVADHNDPSKIEWIEGSEDVYFGDMVERLILKSKNKEYEYKVYRPIQNGTFNIHSNDYTSLKQLTNDLELILTYTLREELKIMKTDFNKYNLVLIIPDSFNLLIVEELIDMIFTMGFHSILLHTESVCASFGAGISQCCVVDIGAQVTKICCVEDGLCNDSSIYTLQYGGDDLTKFLCHLLTLNEFPYKIGYENLKVNSLQDFKIFDELKMKLASFNEFDLTSNVDEIYVRKFNEKTKLFKFKTFDEGFRSSLLLFNPEIILFEKKLKNLYYKNTDFEEMCFNRINNICDVQEEEVGNEEFSSDVQMKRNESLESKRTKILPLISDVSLPLDIAIARSISKFAKSNLDNGLKAKDVDDKVRKICSSIVLIGGGSKIPNLQNILEEKLLFLMNLSNSETFGLYKTISTEKKSISVTCNISSREIDSRVLIWKGGNVLSKLEIIKDIWTTKSEWEIGGLRKLNLKCLFNLLNHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYI8</accession>
    <name>A0AAD5TYI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007551</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000741">
        <property type="protein sequence ID" value="KAJ3213155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="326"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3213155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="416" mass="45005" checksum="4665868A3F46B0F2" modified="2024-05-29" version="1">MSTSSSSTADKCLSLSGTKFCPQYQSFSVATTFALPNLNPTVADFDKYMTDTFSSSENFSKNIKDFLKCPTSTYTASNQRYFVSVNCALIVDTSVNCNPQKKPEPLCRSVMDTFLNKFVTDLASPGNTTILNKDLCSSNGTSFSELLQTYTILSNNAAPNDSQCISGAPTDISQCGFSSVSEGMNFCATNSAESCCKSTTLGGTVTDLSQLLPIKSSPLTTGGSNLTEATSIPPKNSGLIAANTENKDFSPILIFGVAFATFIGLFSLGLCCCLFSKKKRSSSDVEAKSSFNINKSTSNIYKNEAKVDGSNLTETQNYISSSSPFPVSDTLQAVYDYVPNLSDEIYLYVGDPVLIKQRFDDGWALGYNMTTKQEGSFPMACVAPLDDKKLVKEKDTEFSNRNSSLFNFNNNLTESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYR1</accession>
    <name>A0AAD5TYR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000481">
        <property type="protein sequence ID" value="KAJ3216372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYR1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="387" mass="43979" checksum="C79102E6FE679A74" modified="2024-05-29" version="1">MANYDSINLTSKSILHNNHSTVIIGSHSKLLDDDDEFDQHSDETLRLIKSQFSTRKNNKNKFFYIRKFLTYALCILLLISIFSFLFKQNNTVKDKIVMLISIDSFTPRYLNFNVTPTISSLAANGVRAKFMEPVYPSSTFPNHFSLVTGLYPESHGIIANVFYDTSDNSVFTYTNPLDANNSKWWLGEPIWITAEKNNVRSATCMWPGSEAEIQGFRPSIYEKFSYMDLHTKIDKIFSWLDLPDFPRLITLYIPEVDSAGHTSGPESQLVKDNLALVDKEINYLLDGLKYRGIRENVDLIIVSDHGMTDTTGNYLTYCLEGQHGFNPEMPDMHAMFIANGPSFPKNVVLEGFKNLEIYEMLCNILSIPAAPNNSTAFFSTSKILQNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYR3</accession>
    <name>A0AAD5TYR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005858</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000477">
        <property type="protein sequence ID" value="KAJ3216456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000007">
        <property type="entry name" value="NAD/NADP-dependent betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF4">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="3">
        <location>
            <begin position="36"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="423" mass="45993" checksum="2E9BC73955F7EA15" modified="2024-05-29" version="1" fragment="single">MQTQQLKYASKPLENYINGSHVANENWDLQKLNDPKTFIPVCSPSNGEIISYCPLSNKTDVEIAVKSAKAAFESWSNLTVKSRVQILIRFHQLVIKHSEELADIIVLEHGKTKSEALAEIAKGNETVEYSLSMPQLIQGKWLEVSRGVQCNDSKKPVGVVASIVPFNFPFMVPFWTIPIALATGNTMIIKPSEKVPLTMNKVMELFKEAGLPNGVINLVNGTAEAVLAICDHPDIKAVTFVGTSHVAEIVSKRCRNLNKRVLALGGAKNHLVAAPDAIIEMTAQDVVNSFTGCSGQRCMAASVLLTIGSQPVLLDEIVQRASMLTPGSGNGQMGPVIDLASKEKILKYINESEASGAKILLDGRKPFGNSNEGFWIGPTVILHKNKNDRALHDEIFGPVISILEVATKEEAIEFENANPYGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYX4</accession>
    <name>A0AAD5TYX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-CoA thioesterase 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ACOT8</name>
        <name evidence="7" type="ORF">HK099_005696</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000457">
        <property type="protein sequence ID" value="KAJ3216868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYX4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03444">
        <property type="entry name" value="Thioesterase_II_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03445">
        <property type="entry name" value="Thioesterase_II_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.210:FF:000001">
        <property type="entry name" value="Acyl-CoA thioesterase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="entry name" value="Acyl-CoA thioesterase, double hotdog domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049449">
        <property type="entry name" value="TesB_ACOT8-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025652">
        <property type="entry name" value="TesB_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00189">
        <property type="entry name" value="tesB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066:SF34">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13622">
        <property type="entry name" value="4HBT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02551">
        <property type="entry name" value="Acyl_CoA_thio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA thioesterase-like N-terminal HotDog" evidence="6">
        <location>
            <begin position="31"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA thioesterase 2 C-terminal" evidence="5">
        <location>
            <begin position="192"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="310" mass="35573" checksum="7734B9F6A4AE0CFB" modified="2024-05-29" version="1">MEVEKRLTTLIEQSLELETIELDLFRSKSLWKPTGARGVFGGQIIAQSLAAATKTVESNYKIHSLHSYFLLAGDSTTPIVYKVYKIRDGKSFCTRSVSAKQKGKTIFIMSCSFQTDENSVLEHQNVMPDVPPPENVKTDKEIFKQWLDNSEEHKIPKTYQDYLQIRIQEILPIEFKPIKESVPRDLIKPSKSNPKQYVWLRAQGRLPDDLAFHHCVAAYASDHFLLGTAQLPHVRLSMMATLDHMIWFHKPFRADEWLLFEMESTRSNSGRGLTFGRMFTRDGTLVLSCAQEGVMRAKTMTRKNKTESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ72</accession>
    <name>A0AAD5TZ72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000422">
        <property type="protein sequence ID" value="KAJ3217545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ72"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42871">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42871:SF1">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="61808" checksum="751F584A2329C04A" modified="2024-05-29" version="1">MQESGTEIEKENFLSVTDSITGNTIKIAISEFNTINANAFLKLNSVPLRCYDPGLKNTVVSKTKISLIDGQDGKLYYRGYNIEDLVEKSNFLEVAYLLIYGSLPDKSQLKNWNHNIMHHTYIHVELERQMATYRYDAHPMGMLIGTVASLSTFHPEANPALQANTFRHRIGRSYNNPMPLNADNISADDYCGNIWYMIDKLNQPDFKPDKRLVKVLDKLFILLAENGSNCSTSTMRHLISSGVDPYTALAGSMSALFGERKCHAVIDMLSDIGTVENVQLFLSMVKRKETDTSKLYSNIHIPQHNRKKKVSGKPLRLMGFGHRVYKTVDPRVKIAKSLALEVFEIFGKDDICELAIELEEAALNDEYVTSRKLYPNVDYWTAVILHCCKFPKDMFPVWLAVPRVAGFLAHWIESIDDPEYKIFRPRQIYVGNEIMHVTSKLRRKASNVVELDAAYVRNPTYVDASKRRNESQSVEDLQKLISSTEIAIEKGSSEVEGWKDWIGGKLFGINQERLRETQKELLILLERQKALLEQGREENAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZL9</accession>
    <name>A0AAD5TZL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000769">
        <property type="protein sequence ID" value="KAJ3212644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZL9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="108" mass="12693" checksum="F737C08A1FE04831" modified="2024-05-29" version="1" fragment="single">MTHEENYSNYKAIELENFFEMDEQNLEEATPLTNLILKKVTSSDIKREKNFLLATSKLKGFETYLDSKKFIKNNFFIRILRARFKVPPAISFSLTSLVGVMLLKKFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZP3</accession>
    <name>A0AAD5TZP3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000373">
        <property type="protein sequence ID" value="KAJ3218580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZP3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="364" mass="42688" checksum="CFEB7937EB46E1B9" modified="2024-05-29" version="1">MIVVKQKGKREIKELQAANRLVQSCIIELKETDNLTEYELQILNNIKVYYHQILKSQYITIVCRPLVYMESYLKLALLYQENGFKIFNPVPLSTSVIPRHIVIDTKILLEKILKTKVVPKLDEAKIESGMSFDGMTRTDGISICVLLSKIKTTSYGTSTTSCKRKRTKGEYFQDNIRDVKSNFVVIDPNKRDLLYCLGSNGKKLRYTQMERRKETRSKRYSEIRSEVGIKQNQMNVIVPRKVIDKDAWNIYIKEFFSTWNEKEQVDKNTIFRKLKLNSYYNTQKSEGLFINKFKSIFPDNPTVIIGDWSRSTMKYHVPTKSKELLETFKKRPSSRPWNKNKNVTVHGLLRCQSEKCQQEMNGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZU5</accession>
    <name>A0AAD5TZU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_006517</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010000569">
        <property type="protein sequence ID" value="KAJ3215092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZU5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="11">
        <location>
            <begin position="67"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3215092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="267" mass="30920" checksum="DD186D39566C4855" modified="2024-05-29" version="1">MTSYYKVVITNPGNPAYIPVNSTDDFYNQNEVINMNEQSSRYTSLDINTSLDLALYTSRNLETKKDGKKRYCQKCQRDKPDRAHHCSVCKTCILKMDHHCPWISNCVGFKNYKYFFLFVFYGSIYCIYIFSTIMSFLVALPTEKRNSITFDFQAFLILIISAVFGVCLMIFTAMHLGLILSNRTTIESMEGSGYIKFENLSSGETQVISLKKNNIYHLGSKRLNFNQVFGKEVKNWFNPFNGKQFGDGHNFEINEKVYNKLKETYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZW8</accession>
    <name>A0AAD5TZW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="9">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_004938</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 9">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000366">
        <property type="protein sequence ID" value="KAJ3218755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZW8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000004">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000365">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017751">
        <property type="entry name" value="G3P_DH_NAD-dep_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03376">
        <property type="entry name" value="glycerol3P_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF8">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="10">
        <location>
            <begin position="7"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="11">
        <location>
            <begin position="196"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="271"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3218755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="344" mass="37970" checksum="70A3CC958DD93743" modified="2024-05-29" version="1">MSIVREKVTIIGSGNWGSVIAKIIGNNVRKYPAVFQESVNMYVFEELVQGKKLTEIINETQENVKYLPNVKLPSNIYAEPDLLKSVKDSSLLIFVLPHQFIDGTLKTLKGNIKSDAKAISLIKGVDVRKGGLDLISHVISRELEVDTSVLMGANIASEIAKEEFSESTLGYKNKDNAELFKLLLETPYFKISTINDIAGVELCGALKNVVAIAAGICDGLNAGQNTKAAVIRIGLMEMKKFARLFYDGVRDETFFESCGIADLIATCQGGRNRKIAEAHAFTGKSFAELEETMLNGQKLQGTLTAMEVHQILEKKDLVDQFPLFNSVYEVVFKDVKCSQLLHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U096</accession>
    <name>A0AAD5U096_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000350">
        <property type="protein sequence ID" value="KAJ3219174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U096"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="800" mass="90901" checksum="AFCEF06B24752D3D" modified="2024-05-29" version="1">MLGNDLHNEIGDFKVASVFYIPTSQNSPKLTSFLNSLNDYLMGLQPDEEELPHIEYIYYCNQNFLINDNVILILKEIIKLGDAAKHSQLFIFISEESEALKGQLDFMIDEKYRVIFLNSLKLQEDLSSHVEEFSDSLHLIPPPVKNEKSEGENLAVINLPPAVNFNKSEQSSAIGFSNERFIPFLREMKRIICKELKGAISISLISPYSSRKCGIWNLDSCIQFALRLKLVTYNEVEKTLTLTDKGSYVRDKYRGKQCEDLMARRVSIIESFPARYRDIVSIILEESAKNINNQQELKSSVAAIVSTMGNNKPKVKPKAVRELILQGVDMGIFRTTNKTGIPQVILIRRPDNFMPCKFLELVNVIKNLPPPVSFVNVSNKIGGSQVLFGFEKFKDFVAAAAVEGWIKIEEIDDNVCLSLVEPQPNFQFLLKKALEEQKRLIENGGKLDDSIDVGGISKYCQTGQKSSKPSLHLPDNSRFKLLLDLIGYSFCPISAIGGSLQGFHRNFGYETFKDYLEEAERLGFIKIDRDSGIEWKISKSRLNPPQVKFFSSQVISNEEVLDYKFKPFFDFIKNNYARQEFDYLTIKDFVGELVKDGRFESNLEFFTLSEKQGLIKICSGEINNFESTDFKFKIATKHHLPPLPSKEKYEDDSSVDMNNKNLRCQEEVFFDAEEENNISDNSIETATVSSCGQSSPSLSTHFEEVSKFVQISWKASLNLSFESTLGSIGTIRNNGFGSGTEKKRVFCKGSWDSWKDFAELFDNGNGYYCNNIYLKKGVYEYKNRPSKIGFGGENNILIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0E2</accession>
    <name>A0AAD5U0E2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004352</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000302">
        <property type="protein sequence ID" value="KAJ3220446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0E2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05379">
        <property type="entry name" value="CAP_bacterial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157:SF1">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="3">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="2">
        <location>
            <begin position="296"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="544"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="699" mass="78412" checksum="293CDBBFBA6718CA" modified="2024-05-29" version="1">MESNNKFLVEIKQYSIVQQPKPHISFILTVRINDTHWLIRKRFSDFTNLHQQISEKANIVLPKKHYSFFSRSTLDPLLVEDRRKDLENYLKKLLDESKVLNSKIFMDFLEVPTSLRPGYKSASIAKKDDNASTFNSESWLAEFHRLESICLEIIRSQRYDSITISNNKKKYSTVFICFNKLENWLQTEKECLKYITEEEKFRRLDLLSSLKEKKDTANKSIGYWENKNSNTPSNANVVNSEERNELLRFKGNSQNTENSSPESSLKNPRNQRKFGLATETDLTRPLNSEGLLNLQTKIMEEQDQTLEVFSKVLKNQNVIAQAIGEELDLQNELLGEIDNDLGNFICFTLALASISVATTSETREPTSIEPFEDSISSPSNNNTPIDPTCCQVLSGTSNYRQLKGLAPLKGDRRLDQAARKQCELMLQAKELAHSIDGSKPSSLDEDAGYTQWTGVAQNIYSESKRADNDAERPLNAWFESPGHELNIVGDFDHLGVAFCGDGETTYWVQNFGKGDTDLSQQYTPDSCSTGVIEQEQIILEEPLEETSSYESTQTSIEPTDPPKESFQQTAELVGGDSGISPVQYENSQKTYGSKVEAKPVTTEEEPKLYDATQIQNNQTPQENQTPIQNTADVVKGSTSSGENISQPTTTLEAELAAATEINKSTPPPVPASLQQTSSAINFFVSKAVTGLAALYILAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0S2</accession>
    <name>A0AAD5U0S2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004449</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000313">
        <property type="protein sequence ID" value="KAJ3220143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0S2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24162">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013881">
        <property type="entry name" value="Pre-mRNA_splic_Prp3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027104">
        <property type="entry name" value="Prp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212">
        <property type="entry name" value="U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08572">
        <property type="entry name" value="PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor 3" evidence="7">
        <location>
            <begin position="278"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Small nuclear ribonucleoprotein Prp3 C-terminal" evidence="6">
        <location>
            <begin position="509"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="650" mass="75667" checksum="90516DDB1A4C6A6C" modified="2024-05-29" version="1">MMKRGNEETEDEIEKKKRETQAQFDLLMGGGGGETSNKKIKLDKSETDNGKEEEKEEESRREKRRRGSSKKSREYDREKDYRSEREYRDYRRDDYRRDDDRRYSDRHRNYDRDYDRDYDRDHDRRRDHPSSSSSSARRSSHRDTHSSSRKEEEKKSSEKNTGQGYIGGEKKSNVAKGLGTAIHPALLALQNLEDTDSQQKVLQKTLNLKNLTSVKVNLKQLSSLEKKIEKDEKKKVKMEEKQKNTNSLLNNETGANPYLSESLLNKKKNQNITDRVDDMVNVKSVARPARVLKFVQHGKYIDQANEIRAKAHLERLRQEIDETVRKSGMSMELDLVGDESIRKAPPPNVEWWDIQFLPNGTYKDFEDGLVVLDDDNPIVTNLIQRPIPIQPPNEGPMPAPLPMMLTKKEQKKLRRQNRMEKQKEKRDKIQMGLLPPEQPKVKLSNLMKVLGNQAIMDPTLIEKQVRQQVEERLQQGLKHNAEGKLTDEQRREKREKKKVDDLSKGLQVAVFRITDLTDKRHQFKVIANAEQNNLTGVALLYQNLNLVIVEGGPKAIKFYKKLMLRRIKWAGEEHEEDEDEEEHIQPSGEQGEKNSCVLVWEGLINENNFKPGQGFKLKSFTTEAKAKEFLEKFGCLHYFNAAKNYSAEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0S5</accession>
    <name>A0AAD5U0S5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CIT1</name>
        <name evidence="5" type="ORF">HK099_006849</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000617">
        <property type="protein sequence ID" value="KAJ3214477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0S5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="3">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3214477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="444" mass="49648" checksum="F6C75B345771F9E2" modified="2024-05-29" version="1" fragment="single">MYSISRSQLLNLSKNSNVTARFYSSKPQTLKDRLKEIIPKKQAEVKEFRAKHGSKVLGETTVDMAYGGMRGIKGLIWDPSVLDAEEGIRFRGYTIPECQKLLPKAEGGNEPLPEGLFWLLLTGEIPSTEQVRQLSKDWAARSAIPSYVEDLLDRCPNTLHPMSQFSLAVTALQHESAFAKAYQNGVPKSEYWDYCFEDSNDLIAKLPNIASRIYKNVFKDGKQNFNVDANLDYSENFSKLLGYNDKGFTELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSYAAGLNGLAGPLHGLANQEVLRWIKKMQAEVGTGATDKEISDYLWKTLKSGQVVPGYGHAVLRKTDPRYACQREFALKHLPEDPMFKLVGQVYNLAPGILTEHGKTKNPWPNVDAHSGVLLQYYGFKEEDFYTVLFGVSRSLGALSGLIWDRALGFPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0S7</accession>
    <name>A0AAD5U0S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calcium-binding component of the spindle pole body (SPB) half-bridge</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CDC31</name>
        <name evidence="5" type="ORF">HK099_004198</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000290">
        <property type="protein sequence ID" value="KAJ3220569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0S7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005825">
        <property type="term" value="C:half bridge of spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030474">
        <property type="term" value="P:spindle pole body duplication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000077">
        <property type="entry name" value="Centrin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF48">
        <property type="entry name" value="CENTRIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="114"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="150"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="21943" checksum="435C910E5DC45EAD" modified="2024-05-29" version="1">MSSLQKFSTKRNKVKKELNEDQKTEIKEVPFIHFSENLLHFFSLPLKKAFALFDTDKDNKLDYHELKVAMRALGFDVKKQEVLKILRDFDNEDQGLIDFDDFNKVMTEKILDRDPIEEIKKAFQLFDDDGTGKINLRNLRRVAKEIGEQVDDDELQAMIEEFDLDQDGEINEQEFISIMMDNDDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Z2</accession>
    <name>A0AAD5U0Z2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoinositide 5-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">INP52</name>
        <name evidence="17" type="ORF">HK099_006615</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptojanin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.36" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000583">
        <property type="protein sequence ID" value="KAJ3214905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000029">
        <property type="entry name" value="Inositol polyphosphate 5-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF257">
        <property type="entry name" value="PHOSPHOINOSITIDE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="11 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SAC" evidence="16">
        <location>
            <begin position="132"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="active site" evidence="14">
        <location>
            <position position="1398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1397"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1401"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1427"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3214905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1593" mass="180354" checksum="EE68C9C32FA1C967" modified="2024-05-29" version="1" fragment="single">QNPRSIVLKSKKSTSSLVVEKIGANVILNYTKNTEIKWNEYTPLIQRDVYGTLGLIQINNDVFFSIITQIEKIAEFENNSTVYRILKLSFFSCISNKYDNLSDFTENLLSDQQQSNSDYQQNTVVVHPCQALNKLLLGGSFYFCMDLDLTRNMQKRETDFEIGISKTNLFQSFDTHFVWNQHLLKSILQVREKELGPDLKAEFDESGLAVMLMQGHCSTLEQRVGSFSFKVGIISRLSCNSFCSRFNLCGLVVNGYVLYFVVVPTEFMFFTKNYSFSFTQIRGSVPLFWEQTGFQVTHKFTLTRGFETTGPAIRKHMEELIARYQKVHIVNLLKQNDGAGQEMSLGDSYRLHINKLKDLKDCIVFTSFDFHAVVKRDYEKLSNLTDSVKFASENYDGAILDIQKGVFRTNCLDCLDRTNVVQTVLAKQAVSLFLKSIDASSVAKHDSFLTVFNTLWADNGDWLSKIYAGTGALKSSYTRQGKSTLFGFLDDAAKSVSRLYINNFQDEKRQDLIDLLLGKAVLNNFEEIILRNPLHELVNFEVNEREKEFATREKISIIIASFNVNGKLPHYSEPLEQWLFSRTCIYPELFVISIQELIQLTPGQMVTGDPEKNRDIWENGINKTLNSLVNGEKPEFNYAILRTANLVALGMFVFVREDKVNNIKNMEISIIKTGLGGMAGNKGGIGVSLLYYETRICFVCAHLAAGASNYEDRNRDYKTITEGINFSGKKIDDHDAVFWFGDFNYRISLPNEEVRSCIQNNTLDYLLCSDQLLNQQACGMIFVDYKEGPLNFFPTYKYDTGTSVYDTSEKMRIPSWTDRILYKGNNIKLLEYDRVELTMSDHRPIRGVFEMEVKIVDQQKKEKVLEELYKEKSKNGFKENVNLMMNLKKFKSNIDSSIDKKKSASNPSLKIKNSEVDGFNLIDIEYENINKQPTRIPDKGGFVKSAPVDPFSDDFVENSITDDPFSSTKSTTLASPSSDSSKWWEKDIDETWILKEGDGNKFDYYAPTSELVLNNADFLNSFTPKSTSEKNFIAKSHIAHFLGVKKDEIVVTDVVSTSTGIKNYFFAPTIDGIQVVNAQANTHVDEFGNVLATSASWIKGSGNVNRQSVFCTPIQALKNFASLLDIPYENSEMVETENEEEITISGFSKFGDVTIKTRYYQTEYSLEKVYDLEVPFGIDYWNVFVSLVSGKVVGLNNWSFKEEWEEDTHVKSETRLTKRRDYVYTVVALPRESIAEDRKYVINPADKIASPLGWHNSGSGDLAMTIGNNVISQDDNLQALRTPHKPDYKFNYPVDLTQDATTYWEAGATNTFYITNILHDITYHYGFDEASGNFQYNNFDKGGKGNDRILAKTQSGKYFDNAYFVTPPDGKSGEMGMFLFKTTPTRDGDMDNTVVLHELMHGINTRLTGGKSNSNCLSNDVGKGFNEGMADVNAFVLTTKASDNRNTDKSAGRYVTNSPNGVRGLAYSTDMVRNPSTYKDFSTTTGHGAGAVFASMMFEVFWNIVDKSGYTSEILKDVKSGKGNSDFYQIIFDGLKLQPCNPSYKAIRDSLLLADKNKGSKYFCEIWRGFAKRGMGLNADSSYVNNFELPQGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U126</accession>
    <name>A0AAD5U126_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Coq1 putative hexaprenyl diphosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COQ1</name>
        <name evidence="8" type="ORF">HK099_003992</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000271">
        <property type="protein sequence ID" value="KAJ3220815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U126"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF69">
        <property type="entry name" value="ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="296" mass="32638" checksum="BBE86EF0E82DF261" modified="2024-05-29" version="1">MTRDDKKFQLDQKTLDTPISSLDNSLLNNTGNPLILPSQKRLAEITEMIHTASLLHDDVIDTSFQRRSQPSANAEFGNKMAILAGDFLLARASTALARLRNVEVVELLATVISNLVEGEFMQLRNSSVEGDSKIGKFDYYLEKTYLKTASLIALSCKACVVLGGSGDKYSEMAFNYGKNVGLAFQLIDDMLDFVVTADQMGKPVNADLKLGLATAPILYAAETYPELWALIERKFAEEGDEKLALNLALKSDGIKRTKELAEKYIKEAVDSISPLPPSQAKDALIYLTHSVINRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1I0</accession>
    <name>A0AAD5U1I0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000257">
        <property type="protein sequence ID" value="KAJ3221019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1I0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="286" mass="33747" checksum="F0DEB9774D92839A" modified="2024-05-29" version="1">MQNFNSYEESCNSPTTSKKLLQNQKYKKENYKNNNENVPVTGLSHSYIYPEWWGHREHVPSNPSKRGINLSSGLYKALENKCVKSNQLNLSKLEESDQKLINEINEVYVSNYYPFTKRMIDESTQTKVKKNNDFLEKTPNINQPDLKPTENLSLNTNISADEEQKLNFFNYNEDNIKTDKVITRIIATKNKKDNEKEIYQKNKKDNEKELHQKHRKDNKKEFYQINKKKHLIEDFKLNNSNLEKIETKEKKQKKKGISNNPNSKKSVINIAREFLQSDFINCLDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1S7</accession>
    <name>A0AAD5U1S7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bacteriophage/plasmid primase P4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000410">
        <property type="protein sequence ID" value="KAJ3217786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1S7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051620">
        <property type="entry name" value="ORF904-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014818">
        <property type="entry name" value="Phage/plasmid_primase_P4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372">
        <property type="entry name" value="ATP BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372:SF2">
        <property type="entry name" value="SF3 HELICASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08706">
        <property type="entry name" value="D5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage/plasmid primase P4 C-terminal" evidence="2">
        <location>
            <begin position="12"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="39078" checksum="DF851D0FA2A63E56" modified="2024-05-29" version="1">MRSLINKLNLPSFKKDIVEEAKLGYKEPNFKYKLNTKAYLVPFKNGVFNMYTREFRQTERDDYVNLTFNFDYDPSIKNEKVITFIKQILPNKRIREYVLSEFAKCLNGEIPNTKFLIFVGKGANGKSHTLLTRKRNNPNETSTEKLKLLNKRFAFLSEPEEGEKFNVACNEVPKVKNEDAVWRRLRVIDFTSKFKIDPDPNVQNEFILDPTIPFLMRKDVTWKQTFMNILLEYSNVDIEEPPEVDASTANYRKNNDEFIKWCEENIEFYENGILKMKELCERRFPNGESLKKKGVFIKDFEEFLKKTFPKIDTTQISSSHKSFLQRMEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Y6</accession>
    <name>A0AAD5U1Y6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005775</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000466">
        <property type="protein sequence ID" value="KAJ3216667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Y6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="479"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="229"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="368"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3216667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="540" mass="61329" checksum="3FF23F2659652FA8" modified="2024-05-29" version="1">MIRPEDDLSNDEEEEVHAALPIGSLATGEGALMRNIYNKNLMVSPEKNSLLKDKDIQSCLDSYHFYNSSSHQDLDYDNLHSYHVDDYQSPSSNHQQNSSTNSSHHTTSLNLDFWQHSNLHNNSISSNNDSYNLKPFRHKNFPIHETHSSFPPYSNRTFESKDHNSAPFDLLDPITIPSMTQLPFQPSNYSNFEPLNFYTKPKLNSISQQHPPHTPLLNKTRKQLPSFIKTDNVGSSDLHSPPLSLQHTYYPTPFPSSNNSPFPSSSNGGNQLSAKNNPTQIPSPYTTSSNTFFPPTSNPSYSSSTNISSPEKIDQFHQQHPPPPPPPVPPVACDLFNDFSTKALRFSTTASNVMLDDLENKDKLGKNANSFQDFNTRPPPTLPTTSKITKDNNNSVVNNINNNLMHSEQQQHQLKKKKNTNNTNNFEDDFESDGLISLLYKPKTFLGNDKKYFECACEWFEENGDPIQKLEESSGQREFLCETCQRSFLRKQDLRRHIVNTHQREKKSLKCPKCNGSFSRSDALFRHSQTKKCSGNVVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U227</accession>
    <name>A0AAD5U227_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003417</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000224">
        <property type="protein sequence ID" value="KAJ3221537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U227"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052557">
        <property type="entry name" value="CAP/Cytokinesis_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46333:SF2">
        <property type="entry name" value="CYTOKINESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="3">
        <location>
            <begin position="134"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="718" mass="83069" checksum="3B419413D1B5D65E" modified="2024-05-29" version="1">MLNLFKFEIYDESEFEKIISENQVVLCFFHNISDSRSQKSNDVYPKFESFSQKYTQIKFASIDVEKVNISSENIRYIPTFITYLMGKRFEVILETGDLEDMLLKVLEELDYLKERAHSNKSFTNEKFSEKEAWTILFIGEALKDYEGNHINDLSFSKGDMIEVRGIESEHWQNGVNLSTNDFGSFPSKFISQQDFGLGTSAFSSSNKTLEKTNTATKPAFFSPTKKLSTSNSNMDVTTTTEFASHRGIEKRMAPPLPERPKNSVQNANINNRDVFSKLENVEDSSEFIQNYDFLFADEYASNCPKECESSIKNLANYLGNFSEDPYYTCRVIYTWIALNIHYDVEGFLKGNIKRQDSESCLRSKTAVCSGYSQIFKSLCDELNIRCTIINGYGKGYGTSAGDEKIILYNGSMCNHAWCSVEINQDIFFIENTWGAGYLCSNNTYCKKFNDFYFLTSPKNFILNHFPEKKRYQYLEQNLSESEFLRLPCLKPAFFKLKCTLIKPRNFENHSDFMSIIEVSQPEEVYEIEIKVGGVKDEDENCLIVNFSWAKFSEQVKCLGQMHRKSDGFSYFNVKGICPEYGEGRLNIFERKNNEEVINFLIKNKHVAKNQNCFAQKFSSEIEFTLLKPIFNNLQLNQRYDFILKPYTKLQTISDKLSVVICFDGKVVNFKKDTVDGFFILDNFLIEFEGQYMVGYMEGFGEISGLYTFQGNSYNFLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U259</accession>
    <name>A0AAD5U259_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription and mRNA export factor SUS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ENY2</name>
        <name evidence="10" type="synonym">SUS1</name>
        <name evidence="11" type="ORF">HK099_003095</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
            <location evidence="10">Nucleoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
            <location evidence="10">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ENY2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000208">
        <property type="protein sequence ID" value="KAJ3221801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U259"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071819">
        <property type="term" value="C:DUBm complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.140:FF:000001">
        <property type="entry name" value="Transcription and mRNA export factor ENY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03046">
        <property type="entry name" value="ENY2_Sus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018783">
        <property type="entry name" value="TF_ENY2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038212">
        <property type="entry name" value="TF_EnY2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12514">
        <property type="entry name" value="ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10163">
        <property type="entry name" value="EnY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0010">Activator</keyword>
    <keyword evidence="3 10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 10" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="91" mass="10642" checksum="871333EA6D45199B" modified="2024-05-29" version="1">MKTKKIFSNFNRQFQDKRQLRNIIDQKLVKSGEKERLKQLLRQRLTQCGWRDDLKAHCKDVVKGKGMDQVSVEDLINEITPKGRGSIGPFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U295</accession>
    <name>A0AAD5U295_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000198">
        <property type="protein sequence ID" value="KAJ3221968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U295"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="131"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="255"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="468" mass="54128" checksum="C26B70B66ED2279B" modified="2024-05-29" version="1" fragment="single">MNAIKKHQKKRKLSKSIIDCNTKLDLKISSADIETKEQIHDLQLKFLQKIENLNESIVEKDKEIRFLTIKNQRQFKIQFDHIQEIEKLQSVVSQQRNAIEAFFKNATDEKTFRDQSNENMELLIDLHTNLVKENEVEVQTLKSTNLDLEKNILSLQQKMKDLEKINLEKVKNLEDSINENSDLNTKADALHTKIQSLESEVAVAQKEELQKEIISSNSKNLKLIEENHALKKELYEKDTLIKVFDSKSLSNTKEHSKSEAQNIKLSEENKDLLEKYKNLKQKVSEFNKNNESNIQNLEEKISVLEKKNFVLTEENKKLVLQKKKFRNTCETNELVENGSENMSTIKEGNSVLENNNAENILKLSQEIEILKNQNRNSLAKNAPKKKRNQKEMDNAEIDVLKITKKKSNQKQKKVGNDDQKKVEEDTCKESSVTSEDVMLINTLASIEEGCNPLNIGNTENVVKKKRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2E2</accession>
    <name>A0AAD5U2E2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Mediator complex subunit 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MED11</name>
        <name evidence="5" type="ORF">HK099_004870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the Mediator complex subunit 11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000359">
        <property type="protein sequence ID" value="KAJ3218940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2E2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019404">
        <property type="entry name" value="Mediator_Med11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10280">
        <property type="entry name" value="Med11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3218940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="141" mass="16223" checksum="05453B3144B260B0" modified="2024-05-29" version="1">MSIENEIKTSLEELYDLEQIIVSLLDLTSNSVKILSDDNLIIEETKEEQEKVFNSIMETIMEIQQRMRRIFRSLFYSGILNSGKSIPYKANLFGEEKDFELNSQGLALVLEKVKFDLNNLNKIELGEIDIGDGVNLDKMIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2G8</accession>
    <name>A0AAD5U2G8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cilia- and flagella-associated protein 61 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000204">
        <property type="protein sequence ID" value="KAJ3221864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038884">
        <property type="entry name" value="CFAP61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056299">
        <property type="entry name" value="CFAP61_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032151">
        <property type="entry name" value="CFAP61_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21178">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21178:SF8">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23150">
        <property type="entry name" value="CFAP61_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16092">
        <property type="entry name" value="CFAP61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cilia- and flagella-associated protein 61 N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="CFAP61 dimerisation" evidence="3">
        <location>
            <begin position="1099"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1303" mass="149773" checksum="5EFF5D4F43EE0E27" modified="2024-05-29" version="1">MISIRRAELVDVNAIKQLSAECFVKKGSIEQHTQTQTYEDTEKILKQRFGNYRSIEDTTAFSVVGVREEKIIGFAAFTSCPPGWVDGSEVETEAQEKSNSIDITTLSQLNWAHWITSQYETKDIFLYNTKFLRFFVSTFVEGPEFLETAIRNLLICLPAVKQIGFFLNENTHLFSPLSTPKHVHLTSLESASLQQQNSLALAEGGTIQGTEEMKKKNNFNKRHRRINLGLHNGKIRSKIKKNKDGKIIKDERFFKLNLKIGEANGYNFYSCFRYDILPPFRVRKARVEDMDDLVPMLKKQHLLNKENNDAFLANLLESIDPNAKTLVAEVKNRKVKLKNIFLKSDNQVLGFMNLTSEFNLKNLTSTFDVTTYDNFYKDPPPPSRVESEIIETRPNSSKSIKCADDAIGNPISFKDFNINKVELSVQKNSRENLETVAKSDVQNDLLERNPSENEENYPEITNENIATLGDQSEGSASEKSTPQTPLEKTEPNAFCIRLFYLEEPYHDLILEVIKSAFNHFSDRDYCVLTMPTIASELGRLSLVQSKLGKTENHCLYVINRFTLSESIVVRMADNCDLKSIKNLVSGMPIEQQILNNFKAAMPVHRSQKNHDDEKEIEYRSFIATHQEQVVGFVILKTLEDETSYINQFDIEHYIKVEQHDLSSKPVEMVHFIINPLFEVQSRWFFEEVMRISGITLIVYPVTEFAKQDYATGKIVKSEMIPVKRRRQIQFPNNMKDGTKLTVNAKIVVVGGSDAGLSFLENLVYTPHLRFSNLTLISPEGIPIEESLVETHCFSSTELKQIGLDYYVNVIKTGVNAIDRVHKTILLLNELRLSYDYLILTPTVNFDIRSLTPKLESVEGVYTLNRLNSEKISRAVEKFYNTKVTREDVDEFQEQKVDENIVPTCVVYGKTINAYAAVNMLLKKRIPGNNIILVVPKSQIQDLGVFNNQTLEVMVNENTKKFGVKIYKDYKLSKWETQHNTLTSITIKSQEDKSLISIPNTDLLLYADEKSVDTETFKAINDSCLVFDGLLVIDKYFRTQDPYIFAAGSVCKYSSSYKTPWSHSQYNSREIGKKMAEILLPLFNSALYSHTLEEDDNLLEFTNAKQIGAKLPGNLNYFHFDRPRLFSQVLSMRIQQPNYGRDCVISNPVKPDYFRINVDPYGYIQSLTYLGERPLPTDNISCLYGLNDKILNRLVARFDEVGAGIADFITYLEEEWALPLYHDRFSEYLKRLTDQMLDDAKKNEDLQGLFNRISKIVMKSGCIPEDQRRVLYEYFERLPNRKEWDKSLFDYLVECEIYPKKGHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2L4</accession>
    <name>A0AAD5U2L4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000410">
        <property type="protein sequence ID" value="KAJ3217782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2L4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="265" mass="29690" checksum="65E0F7967B2F0D2A" modified="2024-05-29" version="1">MNIVRISRTLQRGFASNLKNESAIPEEVKKSATETYNKLKDVVTPNFEQADSSAGTTAKDGTSAKETEEFVSHISEKANNAKTTDNNSVGAKVKEKVEDAKQYVGLPIKVPPSSLVDVENYLKKSGLILETNSSIAQEQQNGPPMLPTILNNKMIIPECENISNYERTKTLKTEMPLFQHPVYPKGIHQTNIMVSGRDTRLEVRDNYKPIKMKYTIPVKNEINNKVLIGGGTSIYNLQYPCKSVCNQFNQCKNLECLSKFHTFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2V1</accession>
    <name>A0AAD5U2V1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="13">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_004026</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000275">
        <property type="protein sequence ID" value="KAJ3220762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15898">
        <property type="entry name" value="EFh_PI-PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08558">
        <property type="entry name" value="PI-PLCc_eukaryota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000039">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022780">
        <property type="entry name" value="Dynein_light_int_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015359">
        <property type="entry name" value="PLC_EF-hand-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05783">
        <property type="entry name" value="DLIC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09279">
        <property type="entry name" value="EF-hand_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="8 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="16">
        <location>
            <begin position="1024"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="15">
        <location>
            <begin position="1128"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1402"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1408"/>
            <end position="1424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00059664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3220762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1481" mass="169283" checksum="CF4D91F99B6A91C3" modified="2024-05-29" version="1">MTVEVESDIWNTILDSVSKTKQIKTKNLIFLGEKQSGKSTLLNELKLLFDPDYVLNDKKVNDLALSYSYCELKDELDSEETFARLGFFQLSGDNSSKNLLPFALEKNLQNSVVIICLDWSKPHLFISELKKFLVNIENVFSAACLKEKITIESLKEEVEEFFRSYVDPISNDLFVEKKSEDSGSKDLNNFAGENKDQRTPASISLEEKARNLLLPLGEGVLSNNLGLKLLIVCTKSDQTTVLERDQEYREEKFDLIQQVLRTVCLKFGAALFYTSTHKISSIQLLKDYLYYLAFNQNATELSKQKNKNKSQQQQQTQQPHGSGQQNSFNQKALVIERDEVFVPIGWDSVNKILILEKNFKINEKYYFKENLPTEELMKKIEESYSLEVKKFESIGDSLKISNYFEAEDENKFLESCFNTLSAMGGGGMGSSNLGVSPNSSTSRILNAVTGNSSLSTGTNENESDRQNNESSNTDEDVATKLARLGKLKESSGIKKSTSTESSSSLPSTGKDQNEKNSFQIFAVLLAKYSNKSDMLKLDKFDSKVSLKSIFSKSSKNNDHMNTSLKTTTFTQIPEKKPKFYQKSAITRKLNLNFNTFQINVKKLKKIEKLVDIFLIKEIRLGQCTSGFQNFGIKPENEDKAFSIVHYDGQKIDILNFLANSKEERDKFLSILNLYRQHSFDFEYYLFGAWVYVNNQNDNRDSFLMLHEVVDVFKYLNLKITVRELLEDLKKIGLENQKQINFEQFKQVFEKKSFNSSLHDIFNSYSSDKVKLTLEEFTNFVIEVQENNWTAEYCLDIFNKYLTDDDEQKMDYHCFTKFLFSEDNSIFLLSKEVVQDMTLPLQNYFMNSSHNTYLLEDQLKGNSSIEGYIRVLLNGCRCLEIDCWDGSEGEPIVYHGMTLTTKILFADVIKVIKTYAFVASPYPVILSLETHCTIEQQKKMAKYLISILKEELIVNHLKEDELNFPSPEDLKFKFLLKGKGIMKKDQNGNLTESFNSGEELNCVNDTVDNSKVTQSSSANKISEELAKLMIYFQSVKFSNFEDNMKYKFNQMCSIGESKSVMLSKTQREQYFKHNQKFFTRVYPKGVRVDSSNYNPITHWNSGCQMVALNHQTYDKGMQINQAMFMDNGRSGYILKPVKSDIPLKPVTITVTIISAHNLPKSKGNVKEEVMDPFIEVELFGEESEEKRDSDDMNVRLRGIEEEEEDLQFKFKTKYINNNGLNAVFNETFKFKLKNNNNLNHNFLRFKIIDTENLKNDFIACCCLHLSTLGKGYRNAVLYDWKGELLLVSKLLLHIDVEEDIKPNNSVPENSVDVKQVESKTDSRVEEVPNLSNAVLDEKENLVEPGLTKTGTKEPNVVKAEAETLNSTIENVGNTDRSLQEDTEVKKDVNVKATGVKGTEVSTIVSNSGSDEKKKDSIDDNEKNKSGEVEIVIGIEEGSKKFDTETPKSRPVYERTNKFISNFNTEPAPIVDSKVALNVEPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Y6</accession>
    <name>A0AAD5U2Y6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002439</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the nascent polypeptide-associated complex (NAC).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NAC-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000180">
        <property type="protein sequence ID" value="KAJ3222337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Y6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22055">
        <property type="entry name" value="NAC_BTF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000001">
        <property type="entry name" value="Transcription factor BTF3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039370">
        <property type="entry name" value="BTF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10351">
        <property type="entry name" value="TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="NAC-A/B" evidence="4">
        <location>
            <begin position="36"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="343" mass="39102" checksum="090C8D3921B6AE68" modified="2024-05-29" version="1">MNPERLAKLQANAASVRIGGKGTARRKVKKVHKTASGDDKKLQTALKKLNMQPLAGIEEVNMFKQDGTVLHFINPKVECSVAHSTLSIQGAGEVKELGELVPGILSQLGPDSLNSLKKLAENFQQAAKGGLDSNDDDVPDLVENLSDEDLKFVHEIEDSDEYLLHKGKWLILFYAEWNEDSLKVSKEFSNYKNLPNDLNVAKIDMNKNRVTSTRFIINKLPQIFFLNNYEGEEAKNKRQLRSLKELSPTCFKEKCVLNWLGNDWGEKEIDYWFDPFGFYGNLLGFGVNMFFGFLKFWWLFVFLAVASVAYQYYIAISTTLKKNEFHESYDSLSDFAKDKKKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U367</accession>
    <name>A0AAD5U367_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000155">
        <property type="protein sequence ID" value="KAJ3222876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U367"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF150">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STK11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="178"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="64"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="596" mass="65852" checksum="993A70049ADB6F1F" modified="2024-05-29" version="1">MEQHSIQPTTSFQNSNSNIREGNDNATNKAVDIPENMNKILPTESKLQNSPLVATFISRNSSFSRVSTTSSNSSDELNASNKHNDSTSSTNFTGSLTENSNLNSNVENIFNFTEEEDLFLTSDALIRKKTQQNKNSLTSPSSHLHFRRSSASQEEIKETLNASICEDSLTGVRVLNQYKISKILGRGSYGVVHLGEDQEKHIPVAIKEFSKLKLLKTKQQKLQQLNSGFGGKLFARGRGRGGMRGGRPSSSAPASLDQNPIDLVRNEVAIFKKLNHVNVVKLYEVLDSPTDVNGNNNLLTSFSKDSLYMVFECCENGPIMDLSIDNKVKPFSEVQARRAFQQLILGIEYLHENGISHRDIKPDNILLSSDGTLKIVDFGVSEMFVKGTDLSDRSAGSPAFFSPELCVARHGDVSSKAADIWAMGITLYCLIFGKLPFSGASILDIYENIKTQIPVYPVENLNPMLIDLFDKILDKNPCTRITMDSLRNHAWVTDNGNQPIPSKEVNCVGLVTYITEEEYNNAVKKIQGLFTVIKAASKFKHGSKSYSLNSLNNRASLQSLSSLSSTIEEYSNHSIKDLSAVHINDVSCNNENTGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3J8</accession>
    <name>A0AAD5U3J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_001709</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000151">
        <property type="protein sequence ID" value="KAJ3222953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3J8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF119">
        <property type="entry name" value="ROA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="499"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="536"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="990"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1030"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1069"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1102"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1215"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="19"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="635"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1241" mass="140012" checksum="DFE264F756AAF11B" modified="2024-05-29" version="1">MNLSSSSSFELCVKDLSILTNTNLKDTNQKKKYIINDINFSIKPGSIVAIMGASGCGKTTLLHSLAGINLNLQKEGEIEINGTELSKFKQKSLISYLRQDIIMIPYLTVRETLLFAAKLRLNSNIPAAKKLEIVEETILELGLSSCANSFIGNEWRSGISGGEKRRVALAIQLLQNPSILFCDEPTTGLDSFTSLALIQTLVALAKKGKTICISIHQPSSTIFELFDEILLLSKGEQIFFGTPDQSVKHFTNLNISFPSEANPADWLLDISTDNIQEENLIDRNLNFSKIWKNEGLKINSTSEIDEDNDSTLLNGEGLLENYFAFDGILKDNFLANKAEKTNLTIEEEENYSKNNNRASLIYQISTLTGRSVKIMFRDPLMFFGSVFEVIFFSVCVGLIFFQMPEDLAGIYSRKSILYLISSLQPYLFLIYMIYKLSEEIKVFDREREDNMYTVLAYFVSSFIANFPLQLLTCLLYSLILYFMTGLRFEGDLMQKIWNLGVFTAVNGALQLISTSFAYFTIAIFRDFTTASLFANFFYTFFALSSGFFVPYQIMPFFLSWIKDVSQVSFAYRILMSNEFENRIFECPGLLPEGSTQTIPQCIGNTSILQNGFNLNENFKNFIGLLGNFIFFTITTELKDVTIKIEKKGFTKTILDNVSVSFPAGKLSVILGPSGAGKSTLLKVLTNQPLNIPNLSKLTKTGETYFNDEIINDLSSVCSYVCQDDSHLIPSLTARETLRFAAFLRLPKNLTKEEKILRAEEILSLLDLNDCANVRVGSDIVKGLSGGEKRRLSIGIQMINDPLILVIDEPTSGLDSSTAKNLMMQLKVIAETGRTVICSIHQPRPDVFHHFDKVLLLSYGRVLFSGSNLNSYLHGIGFSIPSDNNTADYALSLSIIDHRNEESTLIFQKLVSKWKELGVHFEKALVPDSITNIEQEKNSNESHRKLQQQPKQLNSLIERIKLQQQKINFFNVLSILIKRSWINLKRQKNLFFARVFQIAVLGHCVVLLTFFQKLQFGQPFIQSRIGLLQHLSCGVIAGMVNCIISFPQLLNSFKFERTEKVYTSTAFLLSYSFIEIPFEILASLALNSVAFFYIGLRFSPLNFLLATISIFCSYNAGESIGIACFAIFGHVGFSIQVTSAFLSISTMLTGFLSVDNSLLLFDKISYLTPIRYVARILAINEFTDLEFTCTKREIAESTCFFNNGNVILELYKMDNLWFNFWVLILVTFLYRLIAFVVLTLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4I7</accession>
    <name>A0AAD5U4I7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003731</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000249">
        <property type="protein sequence ID" value="KAJ3221135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033553">
        <property type="term" value="C:rDNA heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070824">
        <property type="term" value="C:SHREC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038986">
        <property type="entry name" value="Clr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38046">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38046:SF1">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="3">
        <location>
            <begin position="713"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1391" mass="160955" checksum="C400F267882CC6E9" modified="2024-05-29" version="1">MVTMNSSFLLRKQFLGHPGCVSNYLRFRSFNDFAPHYIWLLRVNDGFTNDYAECHCQYCPKYIEMNKMIFLELTLPKRGLINATLFPNFQQIVFRKREIVWVPVRISGAIVRNGVDYVQELEKRKQISKNLHSDEFLKKFSNEDLLREVFYWPAIIMDRFADGVINNHSHSITYNVKLLRDPSSWDLEQKYILPYLSFPSKGEVTVHAGVSQGIQRQLFNGIADAEVNANMFSPFGPFDAKVYEKHDYVNQYSDFHKDVMNCTHYTGIYLGSEVIMLGDFARLSSRGNLNFGQKILKICAILELEENGVKSLFVIGAIFQQITKYMVNLNGPSENFYTHYPHSSWSSMLKSDSTDIILPAWQCHTASHLYGIKKPDFSSLHKIKVDELKGRYYPIRLNCEKYCSQTAYDSLLDFEIYSSSVSEIFKNQNRNKLRDVQRFIPRNQINYSNWLSLGFKATDETFHFDDRDIIDEIQESKMLEHSGNLRSLVLFTRKAKSASEKGVSDLVAQESSSDSENTLPIKKLITPKAKKRLLYSSSSSETEELSTINCPERNCLWQFQSFDKVEMHLSQHHDYGRRQIETVLKSLQSKHSDGTRGLKKSKTNSNKVDWLDARSCPEADCDGKQLFEYYKPLLVANFFKADDLKRHLIEKHEKGVKSNISHDNQLELISPTSEVLKYKNDIIVKYNYLLEVDLLDLNSMVYRNFENFFLRIRDQKFSHHFLNPVDQKELAYYNVIENPMDLMQLSFNLNIDTSVYRTGKLHYFPHTKKKIKYKTLRNLTEIFLDFIQIFLNCFKFNTKFEEIIYQDGLTFFFWFRKEFTNFLNDNVKFHPLLFQNTVNDVISDNDDEEVEVEEISGFVKPLLHVEKGNNIINEKSLCVSPCSTFHESTEEDDVNILEIENKTITRSNSFSQVREFFKEISVNKTRKKFDEEIILQLLNHNNNKLYLNFEETLKALPLENSVLFSENDLYSTLQNESQILAKQSEEVAVDGKNNIDKNFDKFSSSKVVGDKAVVDNEVRKKSDEIDATFDSEIMKEPSPHYSTVKNHSKTNTLIKDIAPFNANSSSSRAASLNSFENVKKDRIFIKEKNNTVGSHLNISTNSPIDSNVSFIKSKIFIKEKKVSSASNENDEKFQSGKITLSSGQKALDLPKTAENSPKRMENEIFLINDKNFTTQNGPIIEAGNDIQNSTQDKLSCNLASNSLDEKHAVSKILLPKEVPENVMVFEFHYDGDIGYSITLAIGYGGIISEGNVKKWTRSCPYAARLKSFQKNFKFVTFYEAKLRKSLSLNKVFNIEGKFSNKDENLIKLLNLKFEKIYKSTFIFQTFKFDNAKEESQFLKLKNILNSRVALVKIGEEFHGFLYFLVEEKRLFGLYGTFGGKKMLFDSVSLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U563</accession>
    <name>A0AAD5U563_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SCP2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000083">
        <property type="protein sequence ID" value="KAJ3224733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U563"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="96"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="181" mass="20149" checksum="C2D0CEFE67B322D8" modified="2024-05-29" version="1">MSNSKKELSHELLPKKNKTTLFSSILIPELQKELDQNSKLAGNLRGLFILQVLHKKKFQTEYYLLFQGRDIKPILSNERPELPKSDSSTFPTPILPVVLVEIEDQDILNFATGGLTGMKAFVGGKIKIVGDLLLAQQLEEVFVKAGGVAKAMSFLEKNKIAGFEVSKPVRKPRTANRSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5B9</accession>
    <name>A0AAD5U5B9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methionine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MSM1</name>
        <name evidence="10" type="ORF">HK099_000979</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5B9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="138"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3223558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="526" mass="60974" checksum="EC1D13EB46AAD7E4" modified="2024-05-29" version="1">MRVFSIVRAKHTLVTNPIFYANDKPHIGHLYTAVISDTISKHNRLRGKKTFLSIGTDEHGLKIMQSAAKKNVDVQDYCKEISQKFKRLFDKAGISHSDFIRTTEKRHEVAVKHLWKLLVERGYIYKGFYEGWFIAKETGSAVEWTQEENYKFKLSDFRLKLLEWLDKNPNLIIPKSRENEVLAILSKPLEDLSISRLATNVNWGILVPNDKNHTIYVWLDALTNYLTVTGYPWIESDELKAFWPPDVHIIGKDILKFHAIYWPSFLLAAGLPLPKKIIAHAHWLKDKKKMSKSIGNVVDPEELIEKYGKEVVKFYLLRDGGIFDDSEFSNESLLFAYTHELKNQYGNLILRSTAKSINKNLTYPSFEAGVLDVEDYKCLEQKLTELPISFNNKFNKGDFSGGLREIFDVISEANIFWQKSEPWKLKKNLLDAEQQKLNLKKFDQVLFWTYESLRISSILLYPIMPEKISMVLKKFKSLDCLNLEDIEEGEFKFADIIKIDYEREKGLLEDSGDLILFPKVIADDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5I9</accession>
    <name>A0AAD5U5I9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007252</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000069">
        <property type="protein sequence ID" value="KAJ3225169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010472">
        <property type="entry name" value="FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014768">
        <property type="entry name" value="GBD/FH3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46345:SF8">
        <property type="entry name" value="FORMIN 3, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46345">
        <property type="entry name" value="INVERTED FORMIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01139">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51232">
        <property type="entry name" value="GBD_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBD/FH3" evidence="3">
        <location>
            <begin position="150"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="FH2" evidence="4">
        <location>
            <begin position="1064"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="822"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="920"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1018"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="720"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="958"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1439"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="823"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="842"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="923"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="948"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1031"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1591" mass="180435" checksum="4DB865FE1A14339A" modified="2024-05-29" version="1">MSGDQLFEEMLRDLHMESKAGEMRKLPKESKIQLLKNWQLQKRSGSVISSPPSRNTSSSSRISVEKMSPPAGRSSVVKISQGDIQYPKQKTSSFTSLNSPQTHTFNSTNSTELNENFLSVLNVFKIQEQSRNHMLATFDNQKKERTIENFFQISGNELLKLFDAVMEEMSIFGKAKDNLIRSTSDNKKREVILQFSKNKLKPESSRYLSTTPTGATSFKDSAERGESLLYSIDHFGRIPTSTTINEMSPKEYVLAVASRNTPLKILFRILTELQVSFSINNFFTEKFLNEVVEMQENNVETVKGIQCFTKVLQRLFDITSNKLQQQNASNSVKKYYGGYNYQVNYHQNYADFGISEDELRLESLKCIQLLMRSGLDGWELVVQQEDLIKQVVFCLGLISRSQPNQQKFYTKSSFAKDKSSKKSNWELDILIFDVLTIICSVSFEGHRLILKSFEELRVLKNSKSRFGCIVKYFFENVDEEIDKPNNFKSPNNSVFVDDDDFEIWGNFLLNVLINNANLEMKCSVLTFINSLMIPLQDDTNARLNIRKDLESSHLHSILKKLDQDIPPLEFHDQMQIFEEDRQYDLSIMESEFKKKNLEIFQDLNLSDILTLVKNFDSKNQYYVFSSLKNFTKLIENFSTNISKDHEDIVQIEDILNIFNSITETFFATSVKDSNKISLNELAVNIHQTFKEYSATEVFQEKADQQADGRQRNLGALIIELQNLRDKYQESNQIINSYKILVEELRRENQNVKKDGKRPSAITVLNQGQKNRFETTNASGIDFHHQRNSYENPPQNLHRISTTPLTGHQIYGKPADQQYEYKPLSSSLSTLPSSNSLQGQPLYGSQPNLTISAPPHSNNSATFKPSSSVSISYQPPINSISQQVPSAPGLPPGYTSNIYTNNQIIHPPIYINEVFEKQHRRASAFESNSSSSPSNRNSFEPPPRKDVTPPNSTANQSGLGNLYMQIRKLEIEIEDLKRENLLAQKNYSIGKIRVSDLKEEDLLKVEKFIVKLTEVVPETVSDKSSTDTKAIPPLPPPPPAPLGGPPPPPGPPPPAVPAPPGFKGHTNHKKSKVPLKNLQWKKIKGEGIWKDVSTNKNFVSLLNDEEEISELFSKTATKKNAAKENVKAAEKPTVTIINLLKSDRSRNIAIMLAGLRKSNSAILEAILKIDDNALSEDNLMVVRQYVPTEEEVEIVRNFDGDVNLLGEAEKYIRVISNCTRLPQRLDCMIFRKKLANELREVIPDLDAVQSACEQLRASSLLQNLLHCILELGNYLNGDTFRGNATGFQVNGLLTLRDTKSNSKKYPTLLHYLVDKTGKLHPETLNYMKELSSVSLTSRVCIPALLTTCKNLSVGLENIKNEINEMKNILAAYPNESDFFVTIMNDFFLQYESKISSVKTTAEIVEKSVKEIIIYFGDDFRERAEAPEDFFGIFCTFNEMIQCAKKENEIVEKKLQKAINNNKKHNVQKTISGENSAENGSASAKFASDYAPKGTFLQMIKPEKDGFARLKPPPGQKGLLQRGTLRKNTFDQILKSRKTVKKENSSAATENIALSDNKIQLSDKEKFFEEIYLDDENDTSLAKIVFGEENILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6D8</accession>
    <name>A0AAD5U6D8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytosolic carboxypeptidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AGBL3</name>
        <name evidence="6" type="ORF">HK099_005877</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6D8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050821">
        <property type="entry name" value="Cytosolic_carboxypeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040626">
        <property type="entry name" value="Pepdidase_M14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756:SF11">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18027">
        <property type="entry name" value="Pepdidase_M14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M14" evidence="5">
        <location>
            <begin position="363"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="656"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="659"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="859" mass="99749" checksum="B6B29C9937E51782" modified="2024-05-29" version="1">MNGSNSESNIRINIPHINYPAKLDETESEEDYEEIQLINTKETSKKITFVIEGVDEKAVKNNINVVEYTSYYSVGKKLTDALKKTMNDSNFINKYFETSSDDSEFEEVQEKKNYNSSHSVLERNLRIMKHTFFNEEPRDLFVEQEISAPVWPKEASICNEASTSISINATDMIKCSKFNEYFSNPSENINIPESYFNSATEKKNLVYDCNFKSISSFYKLKSDEDDTLMFESRFESGNLGEAYRVSKYEYNLKIRPDLNTVGHTSWFYFQVRNGKKNTKYTFNIINFMKKNHLYGKGMKPLFFSTNEFKKKNLGFYRIGKNIKYFKNESNDEPSNQELKSTYTLTFEFEFQENNDTCYFANNFPYTYTDLQKFILEIKKNPLTSKYMYHRVIGQTFAKNNIDCLNISNLETFIGKGVIFLTARVHPGETQSSWAIRSIIEHLLGDSCEAKYLRNTYLFKIIPMCNPDGVIIGNHRCNLKGYDLNRQWTENNNVEKHATEIFQIHNYFKKIAAGRNIELFCDFHGHSKRFGSFTYGCENDIKHPRYSEMMFPYLLEKNSKTLFSLAMSNFKIKKDKLQTARVRVWKNFYVKNSLTYEISFCGANSIVLENEKSGFFFGLQELNQIGKNFFLSLFEYFNKSNTFELENLKNCLLKKNTTSDTDESDTSSDEELIRKSSKKRSKKKLNNTNTNFIIKKDSGINSNLEKKEKIKVKKEITNRSVNIKANEKILKKPTKERVSISNLSTTLITMKNPSFDKHRVITPTKFVFKKEEGGPYLQKQQLQDKCINLLVEELITPKVTLVAETEVENNTTNVKQPAQSKNKFSSHSTARVSLTSVNLALEPPWKAGMKFSKGSVLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6W1</accession>
    <name>A0AAD5U6W1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA delta isomerase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ECI2</name>
        <name evidence="4" type="ORF">HK099_001149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6W1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="245" mass="27625" checksum="E706928114E7AB1E" modified="2024-05-29" version="1">MLPQLETTKIDLSNNDQICTIIFNRPEKKNSMNKQGYKDWFSALNFAKSYEKVKVVILTGAGSYFSAGTDLSPPSNGENPFDREVLERDTKVTRGIIELMIDFPKILIGAVNGPAFGISVTTLTLCDFIYTVPEAVFSTPFMKLALCAEVGKPLTAREFKELGFVNDIFDKKDLLNNVLKISSKICELPTTAVMETKKLIRDGMKGHLKDANDRELRVLVDRFLHEEFQEAMFKFFSSKKTTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U753</accession>
    <name>A0AAD5U753_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">PAB-dependent poly(A)-specific ribonuclease subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PAN3</name>
        <name evidence="9" type="ORF">HK099_003513</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U753"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5160:FF:000002">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex subunit PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030844">
        <property type="entry name" value="PAN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041332">
        <property type="entry name" value="Pan3_CK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272">
        <property type="entry name" value="DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272:SF11">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18101">
        <property type="entry name" value="Pan3_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="190"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="538" mass="61583" checksum="94DCF7DE25FDC2ED" modified="2024-05-29" version="1">MAVANFQKLFDHSPQSTPTSSTGRPHGEPIKITNPSITPTKKITSTPKNEVKSFTVPINKNYNVNPYIYTGSPSAFNPYADFQQQDQIHHQQAYNTMDYSSNHAYSQSHSSTDPLKHHLYNMPQQLQKDANILQRFKSNKNLNSTLFLDENLRVKLLNRLESLNLNTSGHSSSSEPLNIDDYHSLVLLEKNTNNTFGADSGSQCFHGYQSLCYKATSMKDGAVYCLRRIKDFRLTSETAMKSLDPWKRLMHANLVPLKEVFTTKSFGDFSLVFVFQYYEESKTLLNEFLMNDSVKVRITEDQLWSFVTQISSVLKEIHSSGLAARVLHRNLLINPITIKIIEPSKILLTGKNRFRLNCLGILDMITFDNNVVKNLPHYQQQDLLQFGQLITVLGCGSIQAVANPQKAFEILSRLYSGDCKKVCLYLLSKPSSFKTIDDVITMLGPRILQEINASQVYNDFLEGELTKELENGRIVRLFMKMGFINERPEYDMDSRWSETGDRYLIKLFRDHVFHQVDENNRPVLDLSHVLYNMNKATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7G8</accession>
    <name>A0AAD5U7G8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7G8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="197" mass="21808" checksum="95D68E422A253EEB" modified="2024-05-29" version="1">MHKLLRSPQLESQREVALNKTSEEPSLTTVTNTQQNAGVNGNQANGNGNQQNSATFQENSGENQTIIGTENVSNSIVNDNSSTIDNSTNVTNNNITNNVDTDINNNVTVNEDNRQFIKQNEEQTIVNNFHTIQQLQAENSKDYAKENHVQDSDYLSKFGESIPTGELNKGQLLKLILSAKKVSDDSLLMLMQLINNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7J6</accession>
    <name>A0AAD5U7J6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Importin-11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">IPO11</name>
        <name evidence="8" type="ORF">HK099_001433</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000014">
        <property type="protein sequence ID" value="KAJ3227584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058669">
        <property type="entry name" value="TPR_IPO7/11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF7">
        <property type="entry name" value="IMPORTIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25758">
        <property type="entry name" value="TPR_IPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1823"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="24"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1955"/>
            <end position="1985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1964"/>
            <end position="1984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2146" mass="246406" checksum="AC1C10B365A150D9" modified="2024-05-29" version="1">MDLNNVFNELTKASSLNTEIRKEGEEILKQMETHPNFLKSLVLIYCNKNLDLKIRFLSIAYFKNGIDKYWRKTAKFPVSEMEKSEIRELLLSNFQEEEKKLATQSSVAIAKISRFDYPLYWPDLLHRLMNNIQHNAANNNSILVQQNCLITFHQVIKTLCSRSLMSSRKMLQQLAPDILSYLTQNFYSNLNLFLSTVEGNTSPDEKINSINFLKSSTIILRTLRRLSLHGFKDFEANEDNVRLFGSLLEYLKKFLQLRLIYSNSGSLLTSIDLFILKIGKFYLEIVKEKPVNFLSTPNSILVIKYYWSLLDAYLQDETKEFAMYERFLVQGMIIIKCLIKNSDFTLVRKDEDTEKRNQIKQYLTVEFFTPDFVDKMLKTLVTKYLVIAKEDLEHWQDDPESFVQEEEADHWEYNIRACTEKLIMDLFTKNKEILSPVVISMLSAVSENSCVDLKSILLKEAVYRTVGLVSHDLYNHLDFDNWFNSRLIAESTNHQHNYHIIRRRIAVVIGNWISVKASKEIRGSIYTVLLSLMKKEEDLCTRLTAVYNLKICVDDWDFEVDKFFNYFETSLNLFLSLINDTEEFESKIKVLNCLSVIIERMEEKILPFARTITSILPDLWTSSEGHHMFRSAIIVILKSLVKSLKGESLHLQEFVVPLIQSGVDTTQPGHIYLIDDAIELWLSVVQNSPQPTEVLFALLPFGIKLMEYGTDSLKAVLKIVEAYILLNPLSVLQIYAISIFTSLSQLIGSLKPEASKSILHLLDVTIQVCSRDLNLLKPLEEVLSSTGLLTKLLELILLNEEMGFILCSYLSIFARLTLFDANFCITFCKYSGGLLNPPLESVLPMLINAWVEKFDSMAHPKERKLSALALASLLIDNAIIDSKLELILNVLSSVVAEISGDLDNAQIYWKETRGGEEEELFIDTNSFHEARLKELQKFDPVYQENLKTFLNFKLSEYEKIFNIKFGSNTSFRSYLFESENSKVFETLKLKDMDESNANILNTSTKNQFNFDHIPLDFQNKIVNHEKLPLNTSSYNSSLDSHSNEIHHQNTNQFDLTNSVIANDQHLYQTNHQNNLNADINNSINHFSSPHNLTSTSQPYISTFPNPFNTNKRKHKIKYPQQITSEFEWKIPNFIENYCVDKTLDSLLFNDLKVVSNPIGPEFGRMQIVLFPRGIGAGKSTHLSFFLRPIKNSKELEMGSNWERKLTYCKIEVTKFNPFTTYRESYMEIDYGEGAMHNEEVLGFKGVPGVGFGEETFLSNEDLLEVLDYDGSLNFRVSVSQTDIVEIYQLDHFYEGKAFFAVRDSFLLPKFGPKDSQWELEVTTNEDDSFLSIYLLPVKSEIENELGGLFRRVVTTVDVKFFAGQERSALVGNKIFTGSFVFSEEENLKLGWKNFVSSDKILNPLDTYTISVSITVDPKFNQNHQYFPFSQALSSFSLSAKLNLYDQKYSQALQSDTAAKLEIANKKILEQEHLIMELNEYKKEYYNSKNTADSTENFLRLELEELKSKLNDNQIILKNQEATLKNTKCNLLNIKRYMDDTDATYLITHSDSGVILENSFTTDQIGNSEEFLNPNIVENLKRLILTCRSSVDEALIRANDGNYNKVKVAAITADLTMHLAELESARLTFIDLMEENNKNAELDLVEIECLEFDLESSRNLIFEALQKLTLKDEFTNNREEIDFFNSFGNYSDFNNKPRGTEEVLKSYESENTRLKQEINNLNFKLNNFQKFFMEAYELLVGKNNNIVLDQLTNLPSQLHSKINNYDIAEDIASNYPDTKVVTFVQDPQMKMNGPVIEEPTIIFEKWELMSENMVKPNVNTKKKFGTFSLLQIFVIFLGIFGFFASNFTCWNTIYNDAGFHVNNNLNSNSSLSGLDYRKGFIENECFNRNIYSVSHNMQNGYKKLLYYIKFRNLKSNFSLENNLTECKVASRQIASNISRFNVSSLQVTSSLPTTLSNPTTSVPTFSRTASNAVSPSSAATESQNLKTRDDISEANFRNILTAYKNLPIETKLVSNTMMKELLTGRQSISSPTLLPDLTDDTTKDLDKKIIHSVPENLLITTPTKNILQTNIKEVMNGISNIDINMLENEKVGDLPFDSKGASQGEEKDNRMINGKVFSSYAIIEDTQRKDSDFVNNLAVHEFLKENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U894</accession>
    <name>A0AAD5U894_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003873</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U894"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="110" mass="13117" checksum="542FA3558350F3B6" modified="2024-05-29" version="1">MDMMEGNHSQYHLHVNFYLTDDWFSMNVFVYDLKGIVLCLQSGADKEKRARTEVEVRSIKESCDKITETAIEGYFRERGDGREFKRLYSDSLLHLHLFVIFKSFYKKIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8A6</accession>
    <name>A0AAD5U8A6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Orotidine 5'-phosphate decarboxylase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Uridine 5'-monophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">URA3</name>
        <name evidence="9" type="ORF">HK099_007732</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8A6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006222">
        <property type="term" value="P:UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278:SF9">
        <property type="entry name" value="URIDINE 5'-MONOPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="8">
        <location>
            <begin position="32"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="235" mass="26368" checksum="46713B09DEB82FD0" modified="2024-05-29" version="1">MKNSSTYAARSLLHKNPAAKALLNTIERKNTNLCIAADVTTKSELLIIADIIVDFDKNLIEELKNLCEKHDFLIFEDRKFADIGEGIVSGLKEVGLPLDRGLLLLAEMSSQGTLAKGIIHLVECLINSNIGQYTLDTLEMARKNMDFVIGFIGQKRLENEKEDFIYMTPGVNMEVTGDTLGQQYRTPRQVILEEGLDIIIVGRGIYGSQEKNIMVEKAKLYRDAGWKAYLERLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8H0</accession>
    <name>A0AAD5U8H0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000045">
        <property type="protein sequence ID" value="KAJ3226064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8H0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="158" mass="18158" checksum="77C09A39C8C26121" modified="2024-05-29" version="1">MRANQNTSLVEPENCSAFEVPCLEQKFEENNEEDFGDHEIPVNLKRKAEYLSEINIVHLPLLKKNKLTNIPDEKENLPFFEGETTKYNIEVEEVENCAAVDPHGESLMATDHESHSFPLTRRPSFYDDISKVGSLKKSLSVSLVEDWEESELNFEDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U904</accession>
    <name>A0AAD5U904_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U904"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="574" mass="64337" checksum="5E5EEEEDD5A93BFE" modified="2024-05-29" version="1">MFFRSLYSIVRLLPAYYYLKNNNYLSYRLSSSRGLNGNESSLEQFHSNKDIRKGVDEMDLGSIETSLGTDFTAFPLDKQILRHSHSTTSLSREDDFYRTKSRANSIESKNYTSSIASSAGSNNSSPRNDSPLLFGTSLPMRLTRVPSNSSVNSPPSPDTSKPVSINQLSYRRHNHQLFRQRDKRLSLQISQNSLPSSHQLPIFTPPSLGSSLTNNEQHKIIFETDPAPFGIVSNSTPNSPLKKVESFGEFGIFKMDPTPYDVEASSPIPIKKTTFPSSYRDSISPLNPIMFTPKEVGYFEGKPFVEGSPPLAKYLMVDSSLKEFIQDTSKKLTEKKSISALNNQKISTQTLSAKKSQQQLALDRFKNLQSIHGSFSDSINQKVSASVVKEEKKIDNSKNELGYLFESTEKPELVTSGTYENKEVDGAVAGGKTDLKLNNESSTDTEFLKDKADHVNKKEMEKKLFKSFNNHFEQKLSSKANPKEFNSMSLPMLVTGERKFKSNVVGSLESGFKEYKTDNDNFFSLSDDNVDNVNSIINPQNSGIREIQNKKKMEDSLDDELLFTMSELDVGGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U961</accession>
    <name>A0AAD5U961_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Terpene cyclase/mutase family member</fullName>
            <ecNumber evidence="4">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERG7</name>
        <name evidence="7" type="ORF">HK099_007432</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the terpene cyclase/mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000072">
        <property type="protein sequence ID" value="KAJ3225057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U961"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000250">
        <property type="term" value="F:lanosterol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016104">
        <property type="term" value="P:triterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02892">
        <property type="entry name" value="SQCY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000002">
        <property type="entry name" value="Terpene cyclase/mutase family member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032697">
        <property type="entry name" value="SQ_cyclase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018333">
        <property type="entry name" value="Squalene_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002365">
        <property type="entry name" value="Terpene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01787">
        <property type="entry name" value="squalene_cyclas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764:SF20">
        <property type="entry name" value="LANOSTEROL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764">
        <property type="entry name" value="TERPENE CYCLASE/MUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13249">
        <property type="entry name" value="SQHop_cyclase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01074">
        <property type="entry name" value="TERPENE_SYNTHASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Squalene cyclase N-terminal" evidence="6">
        <location>
            <begin position="79"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene cyclase C-terminal" evidence="5">
        <location>
            <begin position="381"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene cyclase C-terminal" evidence="5">
        <location>
            <begin position="508"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="619" mass="71215" checksum="68E3950768A7D470" modified="2024-05-29" version="1">MKSFQQEETLYKSEDLHKWRLKVEDGRQTWHYLQSIEEEKNWPQTECDKYWLGILKDDTSLKKNDCLTAKECARIGFKFFSKLQTDDGHWAGEYGGPMFLLPGYVIAMYVTNSPYPAGYQKEIIRYLKNRANREDGGFGIHIEGVSTVFGTALNYVALRLLGTDAEDPVCQKARATLYRLGGAVGIPSWGKFWLAILNCYEWEGMNPVPTEPWLLPYITPIHPAKMWIHTRQVYLPMGYLYCAKFKAKENKLIQQLRSELYVEDYFDIYWPSQKNNCAKVDLYSPHTVLHDFCFAALSIYEQLPNSWIRERAQKVALEHIRQEDLNTDYACLGPVNKVMNMLVSWLVDGPESVAFKKHLERNNDFLWMANDGMRMNGTNGSQLWDTAFTCQALVESGLSNEKEFEKNVLKALQFLNITQIQENMKDHEKYYRHISKGAWPFSTKTQSYTVSDCTAEGLKAVIMLQNLSYTPKLISEKRMEDAVNVLLSMQNADGGFASYELIRGYQWLEWLNPAEVFDGSWFGSWAICYTYACFFGVESLASAGEFYSNSDSVKRACDFIVSKQMNDGGWGEKYKACELGEWVNHEKSQVVNTAWAVLALMAAKYPNKDIIRRGVQVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U975</accession>
    <name>A0AAD5U975_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004874</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000036">
        <property type="protein sequence ID" value="KAJ3226421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U975"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15841">
        <property type="entry name" value="SNARE_Qc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF72">
        <property type="entry name" value="CAMK PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="229"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="524"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="358"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="239"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="397"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="490"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="558"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3226421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="764" mass="86096" checksum="A1381C426C96DE00" modified="2024-05-29" version="1">MASMRDAMRRLNIIYEACAPEAIAEKAAEKGLDEFTRTKKKINQDVKQVRQALKEREVLIQRHGTSSETAEASYHVRILLRSINEDITRLKALYEKDEKKKGKKRLPEDELKARKEIVELCGQHLAECDDMEKRRFLEKNGVDRSELLQGGTGVSTAVQVRRPYGTDFSQEKMEVNDTRKALFEGTTDKGRKKKADQELVTDDPFVSKLPEIDVEEDFKLMNEKNKLIDKDLEDIGFGVQKLKEIAQGMNQELDLQNDALRDLEKDVDKALDGVDNINIRLKQVVDKQVNKKSQPSVLVKNETDNTLNAFAELRINDLNDKSCMRKSTNVRKDELIQDKIKKPKLWKYFPFSFSYGSSTRSSLGKLKSTKEVGNNRNKTDVSKKDSSSSLVNSTDNICNEKNQTVEVKKTTSTARKSVLASNNKVQPKVDSSRPGSNFSNTTSGALPFSQKKEFPLKSAKNSGPNKSFPGPNLPPKPSKASKSEAVSAKEAAEKEDLERNGRHSEVVALLNGKKVLSDNFTKKYKLGEVLGDGAFGFVLTAQEIASGTEVAVKFIVKKKIPKELMNKHTNLPIEIQILSKLNHPGIIKFVEYIDELDYILLITEMHGTEWELANKKLNPLNNVGLRTEVRAKAVTSPEAKAECSPLCRLTEAQEKAIRRRTSCDLFECIDAHVQVPEDICKKIMSQIVLAIKYMNENKIVHRDIKDENVVIDENYNVKLVDFGSASLIPESRRDYFQKFNGTAHFASPEIVGGSPYRGPEAEIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9L9</accession>
    <name>A0AAD5U9L9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9L9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="55024" checksum="D01C880DA9320496" modified="2024-05-29" version="1">MDNLTTTTISDLVSYVVFKIWFEYDKETLIFISQNSNPHQQPYSISPISELNSMELLDFSYNTPNNEKEGLEELKYNFNRFKNFVYQIQIKSLCSGDCIVLALLFVSRLRKNSKKNFKLDQNGKPLKNSERSLWICCLVLANKYLDDDRFTNKAWSEVSRLPLSELNKAELQCLKILDFGLYVAEKEYTEWLDTLSKFFSEALSKIKENIPKEEVPVNNSKEVDVINSDLKKSFEIRGRELAMIESQKKRRRKLSIEWKSHSYHEQDHQHIPNISDINFQNQQINNFHYDNNFNHSQITSNNSSLANENFKKFPLINLHSDISPQNLHIKIAPTPSALQIPTTTSDNQNSLLYQNNLICQHQQIPSFQFLQQQAPPVTPFTPFHTNIFDTDQVSFTSSTTPDLTNLPSPSFNYNNGKNFNGNQVQQISLPFSNLNINYNNNHMEINNFSNNNMGVVEKDEFSPIEHVMDFNYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9T6</accession>
    <name>A0AAD5U9T6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006127</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000051">
        <property type="protein sequence ID" value="KAJ3225829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9T6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="707"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="742"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="778"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="818"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="854"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="906"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="932"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="10">
        <location>
            <begin position="719"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="1112"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="1159"/>
            <end position="1179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3225829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1186" mass="131899" checksum="53B71ECAC9042EB3" modified="2024-05-29" version="1">MTAFYPRAVISTETEINAPSSTVFDVLLNCSNYPTWNPMIKHIHFLGKEKKFVVGSRAILTVGSLNLPIPVKIKSIQFSETRSEIGWEGVGIPIIDYIAVSALFYCISSEWVWTSDLPAELVSTDKFLISIQAPVNDGTVKLISQKLKPYTFDESIKNNGVIEFPGPFSYGNDGSIHGYDNLQIYFENELVLEKQVYIYPSTLSIAGLYDNSFIFGNDPIASAVLFMSVLNDDPTILPHTTLTLSAYASNCSTVISAKSTMEILSNSSYIVIHGPDCSAPTFVDAIMTGAFEIPLISSSASAAQLSNKRSYPYFMRTQTSSASESTALLNAIKYFNFTHIIAISTDQFPFPEDFYALANRLNISLVANIILNSGQVDFSKQLGLIPNLGVTVIVSNIQDNGEKYDAKVLYEHAMKFGLFEKPYTWFFGSTAGLDFLYYVPDKNRLGMFSTYSSYGEVERIDYATAIVEKWNNYDGNLDTIRDVNFEVGKSNIKNFWDMVSRNATKYHVSGSDVDAILTIANSLHEILYVKKIPLDGKTLYATMRNQSFKGFNGQVFFDQNGDRPQAFGLYSFTDQPNNDANSSVYVGSLSWDPVSLIGEFVLETNTTFQMKFSSNTTEKPIGLICPANCGNGTCALPLQCICNSGYTRDVNFFQNKNMDCTVPLCQTPCKFGECITPNVCKCQKNYFGEDCSIYYLELQTPGITYQFYNGIIGVINIVLAVLAVAVFIGLKYSSFNKVKKFGLDLLQFTVFGTVLGHAGTVTGMIFPNQITCTLKYVLFVSGLTLLLSSLLIRSWRIYYIFERPSSVSSATIITFNKLVMFTFIFVGISAIGLVVSILTDTPSTNILTDVDLDYFYLACTLPTNIGGIIGLVIIALNILLLLIMFLMVAQLSKGVPAGFKESKTSVISYLTFFILVSLTVVEYLKYSETIKTALFGILSAMLFSIPTFFVVIPKLHFVLSKKSRKGADKISTHSLQSSSSSSANITLIPIKKLGNEVSMGNFAHLTPGLLGKWTRKVAYYDRKTNFFTMVNSTSLERDEKPLTCFQINGKNAKVVYKPLKKVEDKVGNMSFNEETVKKLDFNSEKVDLETESETFTKETIEFMIVCGGENHRIYDVNNDGLIDKDDLHEILKLMVGSELEDSQITQLVKTTIIEADILDNDGCISFEEFVLCFEDSQIDDMLTIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAM8</accession>
    <name>A0AAD5UAM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Domain of unknown function at the cortex 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000034">
        <property type="protein sequence ID" value="KAJ3226524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013897">
        <property type="entry name" value="Duc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826:SF2">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08588">
        <property type="entry name" value="Duc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Domain of unknown function at the cortex 1" evidence="2">
        <location>
            <begin position="10"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="393" mass="44267" checksum="B6EBCD4679F397A9" modified="2024-05-29" version="1">MPKSPEDYIIRVRCGPDYNTNNLSVVNVNDEHNPALIDGPNFTGYLGVRFLNFDGVVSKEFKDQGPIKNPQSDYFKGRHRRYSLVLQGRFHHEINGDDIIFGLDADVPTRMPTGIGVAIKIAKWLDPAVEADVYSNKPYIYSPLLCAMNSLGVFSPDSPEINDTDQQTGKLLVEKVNRPLVSVSHHPSVNIGKWSFHSRLVPENVSLLVNDSRFVKPTTPPSEAATGWFGSGKKKDKDTKKVGEDDKAKVELGSYEKRKKYFAELKRRTNVTISPDHIYCMDFYDAYFDINTISLKLPGVSISAFKYWDGQPLRFVAKSKSDPSKVYFTVWFEILDRSELGLEPAEKLPTAPSLALNPNRDSLETSSVHEVPLEVLKITSDNEEDDEFEDAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB05</accession>
    <name>A0AAD5UB05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM3</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MCM3</name>
        <name evidence="15" type="ORF">HK099_000075</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB05"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000008">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008046">
        <property type="entry name" value="Mcm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056575">
        <property type="entry name" value="WH_MCM3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF46">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23191">
        <property type="entry name" value="WHD_MCM3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01659">
        <property type="entry name" value="MCMPROTEIN3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="296"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="683"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="688"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="698"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="727"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="763"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3227821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="866" mass="97226" checksum="343684C7FD3F22B6" modified="2024-05-29" version="1">MESIFLTDDLLHERTRVFREFLDNDYGETIYRENIKSMLQKDKRRLIVNLNHVRQFNRDYAEGLLNHPIDYLPAFEKALLDIVQSYSHDNTPLVSDTSSYSIGLEGSFGNNKVSMAKLNSNLLGKLISIQGIVTRCSLVRPKVVRSVHYCEKTQQFHSREYRDQTQLGHQLPTSSIYPKEDENGNPLTTEFGLSTYRGTQTISIQEMPERAPAGQMPHPVDVILDYDLADTCKPGDRIQIVGVYRSLGRSGSAINSTFKTLILANHIKQLGKSINRFVVSEKDVVEIKKLSKKKNIFELLSSSLAPSIFGHEYIKKAVLLQMLGGMEKNLDNGTHIRGDINILMVGDPSTAKSQMLRFVLNIAPLAIATTGRGTSGVGLTAAVTMDKDTGERRLEAGAMVLADRGIVCIDEFDKMNDIDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAANPVMGQYIDTKEPSKNINLPDSLLSRFDLLFIVLDNLEDEHNRAIAEHVVRMHRYVSPGTEEGMPINEDTFEGVNSYSVRMEADMEDNEATSVFEKFDELLHIGLKPLKAATEKRNKKSKKGVPQFTDLISIPFIKKYIQHAKLNVKPALTQEAADLISSQYSELRAWEDGREKMYRVMPITARTLETLIRLSTAHAKCRLSEKVEESDVEVALEVLEYALYKEVKMKPRKMKKPKVDKDHALSDDTDDGDSSNEEFEEDSSSKNQSLKKENASISSTQVSSQGSVSGSSSAKKKSNVSSSSQLRDGSELLNSNINTENGDVEMKDADVNPEDISGERMKFFEQKLSQARNYVQRNKGVDGEMITLDDCYEFCNMNVGTNDKFSDSEIRACLKVLNDDNRIWFRESEGEVLFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB27</accession>
    <name>A0AAD5UB27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Glycosyltransferase family 2 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_008299</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB27"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="437"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="487"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="58306" checksum="CE7F1D82D3F8FC23" modified="2024-05-29" version="1">MFYNILPVHFVFFLPLGFIGIYRWLWFFAKLVAYMLYSPIIPLQNPTFTCRRDVTILVPTIDAGEEIKLAIKTWMKSEPYEIIFITIPSIKQSLIELGRSVDPNEEIVRVITVDKGNKRKQMVAGVNEVKTALVIFCDDDVLWPSTMGQWLIAPFEDPKVGGIGTSQTVLPINKYFTIWEILAAFRISMRNIEITASTKIDGGVCCLSGRTAAYRTQILKDPEFQREFVNEFWLGKYHQHSGDDKFLTRWLYFHSWKTYMQTCPQVELASTFKDNYKFLIQLLRWTRNTWRSDFKSIFVEKKIWRQHPYTAFTMVDKFFNPITLLLGPVTIIYFLTSPHHTQVLPLWVIFTSYFVYLLITRFIKYCPHFVRRPVDVLLLPIVILFNFYFACLKIYCLFTLHITEWGTRSGADTSGGHDDKVMDQKKGEKRDLHVEAADMEADDKRRSNKPAPGSGVSQLPKKVYGNLKPAIDDEIPYNEPQVEPTPRTKRPPGKKSSLKTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBL3</accession>
    <name>A0AAD5UBL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">cyclin-dependent kinase</fullName>
            <ecNumber evidence="5">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">CDK20</name>
        <name evidence="23" type="ORF">HK099_002908</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
            <location evidence="2">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07832">
        <property type="entry name" value="STKc_CCRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000579">
        <property type="entry name" value="cyclin-dependent kinase 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000406">
        <property type="entry name" value="cyclin-dependent kinase 20 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048002">
        <property type="entry name" value="CDK20-like_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF171">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 20 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="17" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0966">Cell projection</keyword>
    <keyword evidence="14" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="12 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 20 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 21" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="8"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAJ3228403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="333" mass="38022" checksum="E29DB2CFBABE08BA" modified="2024-05-29" version="1">MDTSNYRYKILGKIGEGAHGVVLKAKFIENGEIFALKKVPLRKLEDGLPNTIVREIKALQQIDHQNVVKLREFFPTGSTLTLVFEYMLSDLAEVLRNATQALTEAQIKAYMLMLLKGVAYCHENNIMHRDLKPANLLISPSGILKLADFGLARVHDPKVPRPYSHQVATRFAYFLRWYRAPELLYGARKYDVGVDIWACGCIFGELLNHCPLFLGQNDIDQLYCVQSILGTPTKENWPDLEDLPDYNKIHFPSMPQMDFNNVCPDASQEAINLLKKFLVYPSYSRIAAKEALLDDYFFNNPLPAHHLELPIPIRQPTERKFDVDAPICLNFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRS6</accession>
    <name>A0AAD5XRS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exosome complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C1D</name>
        <name evidence="8" type="ORF">HK099_002061</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001651">
        <property type="protein sequence ID" value="KAJ3201919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3201919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="159" mass="18580" checksum="B905AC48E02B4690" modified="2024-05-29" version="1">MDLNSIETPLFEVEKLIEEVIKIPYENRSESDKLTLIKLNVMLSFTINSLFFGYLKTQGANPSKHAVKSELNRIREKFQKISKISEIMAKRPKNRINEGVVERILEHELNSNVEVKDNIKLKKKRKAEELEKDVVEELENDEDSRLAQIKKSTERKGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSJ0</accession>
    <name>A0AAD5XSJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Probable glutamate--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">HK099_001061</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010001279">
        <property type="protein sequence ID" value="KAJ3204647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSJ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017102">
        <property type="term" value="C:methionyl glutamyl tRNA synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1160.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.800.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000004">
        <property type="entry name" value="Glutamyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000047">
        <property type="entry name" value="tyrosine--tRNA ligase, cytoplasmic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="entry name" value="Glutamyl-trna Synthetase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.800.10">
        <property type="entry name" value="Glutamyl-tRNA Synthetase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF5">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 16" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 16" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="18">
        <location>
            <begin position="839"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="703"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="787"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="718"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="787"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00070830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3204647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1001" mass="113849" checksum="048F355B0F1EB2E2" modified="2024-05-29" version="1">MSQLELVKLIIGKGNNYSALATAHYLILHNKITVEFKSDLNQPETFIEAFPQIKGSLSVTKFLARSYSKQQLYGYSLTIADFAVWGALKGCSGFQKLVNGNKEVGTHLRRWYDFVSSLDFVQKIVEEPKPGKKGKKAGDAPIADQGSFDIGLKDAKYGEVVTRFPPEPSGYLHIGHIKAALLNDYFAKHYGGKLLLRFDDTNPTKEKLEFQEAIQCDLTRMNIQWHKLSHSSDHFDKVYELALQLIKAGKAFVDDTEQQIMRDERMAGINSKNRDMSVEETLKRFQEMKDGTERGLRSCLRARIDMQAKNKTLCDPVIYRCNVEVPHIRTGTKWKMYPTYDFVCPVIDSIEGVTHALRTNEYRDRNVQYDWFLRALNLRYVNVWDFSRINFVYTLLSKRKLTWFVDQKLVSGWDDPRFPTIRGILRRGMTVDALRNYMVLIMHINNSLIKNFTKLMQGASQKDLMMGWEKIWALNKKVIDPISGRYCAINREKIVKVKLTTDLAPYTETKPLHKKNPDVGEKQTTYSSELYLEWDDAVTLEVDEEVTLMDWGNAIVRKIEWLNDSFIGLIHMELNLDGDFKKTKKKITWLSRRSPNKKDDHDLVKLRLHDYDYLITKKKLEEGDELKDFITKETEFVVEAFGDANLKSLKVGTIIQLERKGYYIVDEAYDHSKPDAGMKLICIPDGKESNMMSKAAEVVDTKVAPDTKTATQSKKEVSSSNSKTPSTNSKGGKNSIVDTDDFVHSIGMYRVNNLLGHIPPFDQSKISSMYKKDPLMDSSLVLHKVGKVETDTSKETDTSKPSKPSVKETAVVESSEGGEGKKKSKNAKPEAVVAKEGSVISKLDLVVGKIVDVKKHPDADSLYVEQIDVGEEKPREILSGLVKYMSEKEMKDKLVIVLKNLKPVAMRGIKSYGMVMCSSSDDHTKVEFLIPPNGSQPGDKVYFEGHEGEPEAQLNPKKKIFETVQVDFKTGQDLVAYWKDIPFRTKKGVIKTKSLKDAIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSR3</accession>
    <name>A0AAD5XSR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alginate lyase 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001086">
        <property type="protein sequence ID" value="KAJ3206990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alginate lyase 2" evidence="1">
        <location>
            <begin position="107"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3206990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="339" mass="37221" checksum="F7F5E81A2124605B" modified="2024-05-29" version="1" fragment="single">CSTASQPGKVGDAITCTFDSYKYKSTRKNTIAIFQKNIKVLQSPGLTVARGTYTFGDTTTLTAGEIEIKFLNSKNKSESATIKIVLAAADPGPDPGPDPGTQDPVNINLSKWKLQLPVGPSNDKVLEITQLSTYSSQFFYLNTAKTAYIVNAPVWPPAQPENNLVPAHTPNSKTTRSELRELSSWNFDVGKHTLITKLAVRNTPLSGDTTPSFAGEVVLAQLFCGSNTVINLRYFAKSNEIVIVIEDNGNKSPRRLSSYTLGDIFEVKLEIINKLAYVYYNDAQIISDALVRTSYAKNSCYFKTGVYNQVIPVTTKPDVNNINSQYAEAALHKVIILHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT03</accession>
    <name>A0AAD5XT03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oligoribonuclease, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">REXO2</name>
        <name evidence="6" type="ORF">HK099_008598</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oligoribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000962">
        <property type="protein sequence ID" value="KAJ3209043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT03"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06135">
        <property type="entry name" value="Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000003">
        <property type="entry name" value="Oligoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003765">
        <property type="entry name" value="PRK05359.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="OLIGORIBONUCLEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046:SF0">
        <property type="entry name" value="OLIGORIBONUCLEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="21"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3209043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="215" mass="24643" checksum="7F61648CD2194BE6" modified="2024-05-29" version="1">MNKIGFVSKLFKHQNPMLKNPIVWIDLEMTGLDLKKERIIEISVICSDGNLEKIVEGPNVVINQPVELLNQMDEWCTNQHRKSGLTKAVLESNITTKQAEKQVLDFIKTHIPQGVGVLAGNSIHMDKGKSKKTKMGFGLNVLEFLRKEMPDLLSYLHYRLIDVSTIKELSKRWFPEAFSSAPKKNENHRALDDIKDSITELKYYRNTVFKKSTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT54</accession>
    <name>A0AAD5XT54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SsDNA endodeoxyribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RAD1</name>
        <name evidence="8" type="ORF">HK099_008345</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000901">
        <property type="protein sequence ID" value="KAJ3210229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT54"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003011">
        <property type="entry name" value="Cell_cycle_checkpoint_Rad1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003021">
        <property type="entry name" value="Rad1_Rec1_Rad17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10870:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02144">
        <property type="entry name" value="Rad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01245">
        <property type="entry name" value="RAD1REC1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01246">
        <property type="entry name" value="RAD1REPAIR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042185776" evidence="7">
        <location>
            <begin position="21"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3210229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="540" mass="60932" checksum="2CBA71C621771937" modified="2024-05-29" version="1">MKSTFLLATLFCSISSLTDYHKTSLQLYNQNKLNDAGRFAVEVQRLDYLSNEKNEVVAEKLSDIILSFDVKLDNNGEPTVLANVTVFKLGVPVELGLNNVQIEAGVVMKMKEGERPETAESFDVGLIDLQVQVIAEQVDLAGLVDITRLTIIEKVTEVNGVEVVQSETMQQVFEIKEHKISSKLPCKAMHPKMAIMGSHSEEGTKPSGCNAQRLLQWIESKPLAVKIVFNLLSGIFLGILTLIFFQIMYKLFTFAGYQRVSDEDDDGKILKNISLSPKEVEAGYFLEKENLPKYNDRVQANLDLPKNYFKSFKTEKEDGSDEEELELTFGFDLSNFLTCLGVFENLISSLRITCPKDLSELVLTMEDKGNITVATIKTFEAEIGDDLNDLFTDFPIIGSIIIQAEYLKETFLELDVTSENVFFSFNNENNKSFFKIFAKGLSGEADIKFNKNSEVVENFNCQRAISATYKLNQLHTSFKALSLSTKICIRINKKGFLSFQLMIPKNLQMTNQSYIFSEYIFSPMVDNELDNESQTDAVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUK4</accession>
    <name>A0AAD5XUK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">IQCH-like ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000488">
        <property type="protein sequence ID" value="KAJ3216255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056855">
        <property type="entry name" value="ATP-grasp_IQCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038752">
        <property type="entry name" value="IQCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14465">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14465:SF0">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24923">
        <property type="entry name" value="ATP-grasp_IQCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IQCH-like ATP-grasp" evidence="2">
        <location>
            <begin position="197"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="399" mass="45605" checksum="B90AFC3D3CA9909B" modified="2024-05-29" version="1">MLSHKANHKNSNKNLKNSKNFQPNKLEQNISSESDFLKDQLFTEKNKDVIIVPSLSLDSHLLSEINGLIHYESRLLYNILSLRYQSNRLFYFSSIQIDPAIIDYYFELIKENLEDLQEAKNRFFLISVNDFRNNLCLSHKLLLRPNLLTHVASLLRKDDKSVASDLKVFRGTAYEEKIAEKFALDLNSTKGKDLDWGGKAGSRTIFKELNIPHIPGTYTAEKNLESFFKSIIDVLKNNPNAKKGIVKLDQGFSGKGNATMNVEETNKILHSTEDKEANVEKALVALKKAYLNLKFSCESETIENFTNSLKHLGAIFELFYDTRAKDPKLVTSPSVQVLIKNDLTVITLSTHEQILEGHCYTGCRYPCNEDYREELEKFGKKVGQFLAKKKIADYFSVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV81</accession>
    <name>A0AAD5XV81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF642 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000380">
        <property type="protein sequence ID" value="KAJ3218431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV81"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006946">
        <property type="entry name" value="DGR2-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04862">
        <property type="entry name" value="DUF642"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042036027" description="DUF642 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="DUF642" evidence="2">
        <location>
            <begin position="291"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="452" mass="49106" checksum="77A9FB3C115988D7" modified="2024-05-29" version="1">MLLKNLLSLSAFYTIATVSAAEAPQSIRSVFKRSPLEEPVYSYTTTPPANSFYCADNNGHVTSLSHDTTFQPQVPNTGFCCLYGYLVDQAGTGCYNIPQCDAATSFNCQGGWNDKVHQPLNYYSYGVPTGCCCNWDKISIPGQAACGNKGNKKCALTFDEWTSYPSSNAWSTFYTNFFKSSTPIKSILNNNNFKGYYYVLAREWIAASLNVNSGSDYNEEVAVALKIATAFLSEKSAAASLNNFLPANNDNTYAAGYQYTYVDGTTFTLGQLFYTLNSFNNGKTTAAKCNLVNDGGFENGPLYCPQVTSQGWCIANPSVVPNAWSATQNMIELDKFVVPIQSGDWATDLNPNNQGSISQTVSNLNPNYSYTLSFWLNANPCGGNSYPGYFSVNGVSTNFNYNLNQPYQFISKSFSNLGTSANIVIGSSKPSSGCGPVIDNVQLIANPILSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV94</accession>
    <name>A0AAD5XV94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003232</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC124 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002146">
        <property type="protein sequence ID" value="KAJ3199287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV94"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010422">
        <property type="entry name" value="Ccdc124/Oxs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054414">
        <property type="entry name" value="Ccdc124/Oxs1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054413">
        <property type="entry name" value="LSO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06244">
        <property type="entry name" value="Ccdc124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22048">
        <property type="entry name" value="LSO1_2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="144"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="144"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3199287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="221" mass="25785" checksum="79656D91E8DAA3B5" modified="2024-05-29" version="1" fragment="single">ENTKKTAGLAKKQENQQKKDEVKKQKLEQEEAAKWSKGSLEDKLLQKQQEEEKRLKKLAEKEEARKLLEEEEKEFGKKKPLIRDKKADKKGLNLAKIESEFQPIESFAASGIDDALDLLTLTTSENKNLTGGGKNDNKIEKHPEKRMKSAFAKFEEETLPRLKEENKGLRLSQYKQMLQKLWKKSPDNPLNQENLSYDASRDEEKEFKDKIKEEKLEKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWI4</accession>
    <name>A0AAD5XWI4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001874">
        <property type="protein sequence ID" value="KAJ3200586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWI4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF159">
        <property type="entry name" value="LD03170P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="1">
        <location>
            <begin position="72"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="316" mass="37238" checksum="2FAD607A58BF0FC7" modified="2024-05-29" version="1" fragment="single">MASSENPSIDENLTEKPESNLILLVNRDSKYENDDNYDAMRSDLEDISVNIDNGREEENELFSKEMEEQTKKRNLVLMEIWNSEVQYYKGLIILEEAFMKPLKNCLNTPQEIINSKTLKVIFSNLEPILSLTGELLVDLNNRLFYCKEKTFSKNLDVLESKIFVQFEEFLNNIKKSESKEEIKLGDIFCNMAPFFKIYSTYSMNFNKAIQTVSFEIEHNINFKNFIQDQILQEKDILKDLSFQSYLILPVQRITRYKMLLEDLLNKTTKKQEDFSLLSRSFGIASEMALFVNESIRQNEMFLKMFDIQRNLNNLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWS5</accession>
    <name>A0AAD5XWS5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-binding cassette sub- D member 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ABCD4</name>
        <name evidence="9" type="ORF">HK099_001889</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001589">
        <property type="protein sequence ID" value="KAJ3202314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWS5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015910">
        <property type="term" value="P:long-chain fatty acid import into peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042760">
        <property type="term" value="P:very long-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF59">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORTER ABCD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="3"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="323"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3202314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="537" mass="61035" checksum="7ED6DBEC840C6949" modified="2024-05-29" version="1" fragment="single">MIAYYLALSFVKALVRFTGGFFALKGRLCLSKYLHSNYISKEKFYSICTENEIDNPDQRISQDVERFMECVRKLLESLVIDPFLIAYYTYSTAAINGGNLIGPLVIYTYFLVSCFFCKLAVTPLIPLIFEREAKEGYFRYVHVRIRQFSESISFLNGEHFERLKADGMLDSLLGVQKKVLEKGIAIKFFTEFFNFFGAIVSYLIIAIPIFTGVFDNKSKAELSQIISLNSFTSMYLIYKFTVITDLTDVVGDLAGYTSRLGQFIEVLEKVQQDKDRFSIIVENDAIADTEYFNNHFKGPNSNCIILEKVSVKSPDGEFKFLIRNLNLKLNPGENLLITGSNGSGKSLLLKMLAKFDKYQKYDDTGSTIFIPSFPKVMFVPQIVYLPEFSSINEILGYGCMGNDSGFFSCDVNCVGYREFGISDVLDCLEKVKLTHIIKRIKISGEPLSILSEKFEVATLSPGEKQRLLIARIMLWKPVWAIIDEGLSNIDEDGCKTLFKYLEELKISLIVVEHQDANFFLDNSSLNFKNLVISNDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXK1</accession>
    <name>A0AAD5XXK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000110">
        <property type="protein sequence ID" value="KAJ3223969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXK1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052922">
        <property type="entry name" value="Cytidylate_Kinase-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37816:SF1">
        <property type="entry name" value="TOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37816">
        <property type="entry name" value="YALI0E33011P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="212" mass="24902" checksum="1200EE50003B4258" modified="2024-05-29" version="1">MEWINISVFIRQIKIGSSGSGKSTLGKDIGKVLGIEHLEEDSVQFTNNFARLDDKVSQNIAFQFTKRNREKGYVTDGSWVNLHGIILPQCNVLIFLDYSFFISFFRLVRRTFFRCYYSVNLWGLSDCKESFGQVFQFNSDSVIFHYLKSYFRFKFYGISKHRSLVKSDWKENGFEKAAEVDDRDVWKGERIILHFTHPSEVELWLKSVQKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXM4</accession>
    <name>A0AAD5XXM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-catenin-like protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000092">
        <property type="protein sequence ID" value="KAJ3224460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXM4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:001136">
        <property type="entry name" value="Beta-catenin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039678">
        <property type="entry name" value="CTNNBL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013180">
        <property type="entry name" value="CTNNBL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978:SF0">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08216">
        <property type="entry name" value="CTNNBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01156">
        <property type="entry name" value="DUF1716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Beta-catenin-like protein 1 N-terminal" evidence="6">
        <location>
            <begin position="66"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="647" mass="74385" checksum="FD7834740DF334DC" modified="2024-05-29" version="1">MVLGSEKGSLVAEVGVLAGESCSLAGELCSLSGEDFDAPAPLQKKRKVPDQFDEDNQDLTNKKPVLTEHDEKLKQIIDAAEDLPETIDLATLKKLILKFEKAITKNNQQRSKFQSEPLKFIDSEVDLDQSIKELMVFTAVPELYPKILELGALDSLLSLVIHENTDISVSAIDVLNTLIDEEVIEIEEEKNDTDSEDDEDSNANMVMKKKEGLKLFVNHLMKNNAVDLLIQNINRLNEFENPEDRQAVFNSLSIIESITAIDPTTTEKIINTKGLLKFFVERLKVKNFDSNKAYCVEILNILLNKRQNILFILEFGFMDIILKSLSKYIKKDPPTPDEVEFFENLFNTLCLVLQDPVGKLHFIKGEGIELMIICLKNKKMSRIRSLKALNFSMLYYSDSFEKNEAVQVEKNEDLRNITEKVAIYFLENFGLKTLFPIFLGKGQKTLRKEYEDIFVEAEDDGNFLLDISEIISFFLEHCISIISSLFRSLYFMESSATETSDLKKLKLKLKLKFYESRFEKFERLLNLITLYKLRLNFVEEQLKSKKSNGAEDIEEMHDDEGEYLKRLDSGLFILQKLCFIFGCIFDFDDEESVIRDSMKELLSQKDISVKYIMNILEEYKSNLDVSQSDIQLESDLIVKILLNLKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYC6</accession>
    <name>A0AAD5XYC6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000060">
        <property type="protein sequence ID" value="KAJ3225485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYC6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="190" mass="20729" checksum="E19F90DC19DB870F" modified="2024-05-29" version="1">MVPVLILLEIAFFVLTWIISLMVINLKTLFYEVDVRLGWFIFTIPIFSLLFAPLYFYGKELLLARSLLNGGVVNREEMAHVTPLESVAVGDQRDRTGAGGMNNDFNNTDGVNKNAGPGGNSAGGIPVISNSNNATPVGNNIPVNNNINNQNVNLNNNFAQKNASMVNQEDSIQPGNLSNNKYFTPTSYCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYQ8</accession>
    <name>A0AAD5XYQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000461">
        <property type="protein sequence ID" value="KAJ3216764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYQ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="451" mass="51498" checksum="5385B8CEA3858201" modified="2024-05-29" version="1" fragment="single">MNSNQSFSDNNSEREEKKKKKTKIPSSSERLESSSSQMSLKKKLNKSNSSLLQKKNKIKNASSSALQFNECNNDVFDNNDDDINLCSDNRFGQSTDDFKSQKNKNKNKISSVNLYSSEPNVNKKTDSLSNFQKSNDSLAEIYQSNSIVRGSSHYSRSSDSLQPTASQLFELREAENPSCVVDYSAHHNVNSKTIQDEGKKRTKKKNLENVNSTTANPTSYSASMEPIANNYPMVQHVQQIVLDRGIPQQKKKLTRKAKDKHRSKSQKNKDDHIALEINNPTNNETVTIEKKDIYEEYKHYLKDTSNREIKNSSFHAEELNRADFNLDISNMATTYEDKMKQSAYAKVQATFYEDGNKFRQYYSDSEEDSPYKYSNSKSKYSIKKLINLAKKSETNSTYFLKFFHQILAGCCLASLIFFPVSDLGDPSPSTFMDEKINTTVIRFGVQTELQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ96</accession>
    <name>A0AAD5XZ96_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Hydrolase TatD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000182">
        <property type="protein sequence ID" value="KAJ3222287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ96"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000005">
        <property type="entry name" value="TatD family hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="32532" checksum="05DC55D47CDE7684" modified="2024-05-29" version="1">MSTAKLIDIGANLTYHSLANNINCVIQRAKDNHLKKIVITGTSLKNSKDAIELAKQYPHFLYATVGIHPHDADKHICIKDISHQLENLAIQNLDVVKSLGECGLDFNRNFSTRENQIAMFEIQLKLAEKLKLPIFLHERDAHNDLVLCLKNTLSKDYLCHTVVHCYADGVKEHLEEYLDLGCYIGITGWITEAKRGKDLFEIVNIIPIERLMIETDSPFLKPRNIKDKELRKGRDNEPAYLKYVLRKVAESYSQLAQFQSLDIEEVEEILGNQTTLNAERFFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0M0</accession>
    <name>A0AAD5Y0M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000071">
        <property type="protein sequence ID" value="KAJ3225098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0M0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="17010" checksum="12F0F6A3B0B48B85" modified="2024-05-29" version="1">MSTSSTSLDPFEVSDIVSKLTNAIGLQIENSTKDEIISQLLSKENFKNEDTNLENLENLENLEYNQQFKDYLQKLIIENHYNKNLNQILYLIKQLKKNSNLSKFLSTFPTPNNFLASSLNSKTKSDTHSTGLGLKNRPSLVNLNTQSPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0X0</accession>
    <name>A0AAD5Y0X0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA 3'-terminal phosphate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000227">
        <property type="protein sequence ID" value="KAJ3221490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0X0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003963">
        <property type="term" value="F:RNA-3'-phosphate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036553">
        <property type="entry name" value="RPTC_insert"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="RNA 3' TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF0">
        <property type="entry name" value="RNA 3'-TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="375" mass="41070" checksum="22591B0AA3B7D7B2" modified="2024-05-29" version="1">MCNSIRLAELTIKKKYILLNKKEDKDKKQPTEIDGSLLEGGGQIIRNAVAYSTILKIPIRIKNIRGKRKPPGLRKQHVVGVLAAGQLCDAEIEGAFVGSEVLTYTPKDAVIKSDEIIHIEIGSAGACSLVVQTILPILLFAKTTTTNKEVKVSISGGTNVSFSPPVDYLQHVLFPCLQHNLRISAAITIEKRSFGNSKDGKILLVVKSLDGIGISGINLIKQRCPINSQICYVYGCGTPEIAEKVRNFFTKIFFEVDETSMKVQNNLKSGALGVLLIGRDVDEQVVAVGSGLSTWNTKKFKESKVVEKMMSEACSAYSEMASNEEIIVDQHLQDQLVIFMALGSNTSTYKTGNLTLHTITAIEMAKTFTEVEVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0X9</accession>
    <name>A0AAD5Y0X9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Solute carrier family 40 member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002184</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in iron transport and iron homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000170">
        <property type="protein sequence ID" value="KAJ3222552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0X9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009716">
        <property type="entry name" value="Ferroportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11660:SF57">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 40 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06963">
        <property type="entry name" value="FPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042209211" description="Solute carrier family 40 member" evidence="8">
        <location>
            <begin position="22"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="265" mass="29733" checksum="10E9A19886033F46" modified="2024-05-29" version="1">MAVFSLLIIPVELVLVKVVYNSEPKLSQPKVTRAEAASDISVHNDHSMVSVLKKKFIQSWIIYYDHRVFLASIAMACLYFSVLSNGGQMIAVLKYRGVNDLTIVIMRGLGVLTGLAATYITPLIVSKIGLVRCGLWGLWSQMAFLLPIVIGFFIQGEHKQQIETWLLMIGVSLSRFGLWTFDLCETQILQEQVDNSIAGLISGNQYVFFNLGDLCSFLLTLIFSSPEDFYIPSLISIGSVFFGIIFYTSYVLKERGHLLHFKKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y153</accession>
    <name>A0AAD5Y153_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Septum-promoting GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPG1</name>
        <name evidence="2" type="ORF">HK099_001644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000149">
        <property type="protein sequence ID" value="KAJ3222985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y153"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="16847" checksum="8416DD01BF7E002D" modified="2024-05-29" version="1">MATIPSPNEHKESKKNSVVLKVGLLGDSQIGKTSLMVKYVEGSFDEDYIQTLGVNFMEKTITIRKSDITFSIWDLGGTLSYKKIISQREFVNMLPLVCNDAVALLFMFDLTRKSTLNSIKEWYRQARGFNKGQSMITLQLSLKKNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1U3</accession>
    <name>A0AAD5Y1U3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine transaminase</fullName>
            <ecNumber evidence="4">2.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PSAT1</name>
        <name evidence="13" type="ORF">HK099_008293</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4-(phosphooxy)-L-threonine + 2-oxoglutarate = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-serine + 2-oxoglutarate = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1U3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000010">
        <property type="entry name" value="Phosphoserine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000006">
        <property type="entry name" value="Phosphoserine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003764">
        <property type="entry name" value="PRK05355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01364">
        <property type="entry name" value="serC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247:SF1">
        <property type="entry name" value="PHOSPHOSERINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="12">
        <location>
            <begin position="28"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3227883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="395" mass="44305" checksum="9CCDB1986AC54ADA" modified="2024-05-29" version="1">MSFLTRGVGSIIKSAIIPALAPQKARLAGPAVLPKSVLETAQRELLNFANTGSSVLEISHRSKEFEQVNQEAQQNLKDLLDVPDDYAILFMQGGASAQFSSIYLNLLVNQSKPVDYIVTGIWSEKALKEAKKLGGNCNVVFNLNNSKDKKLPIDDKDWNFSKDSSYIFYVSNETVHGIELNDHEDKFFEKFPKDKVLVCDMSSNILSRKVDVKKFGCIFFGVQKNIGPAGLTVVVIKKELIGTRQDKNVPVPSMLCYKTCYDANSMYNTPPTFSVYLSNLVFKNLKELGGISYMEKLNLEKSNLIYGIIDKRKDVFQCPVEVSLRSRMNIVWRCLGSDGKPSNIVEKEFFDGAERLRLHQLQGHRVVGGVRASLYNAIPMESVLCLADYMNNFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1V9</accession>
    <name>A0AAD5Y1V9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sequence orphan</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000095">
        <property type="protein sequence ID" value="KAJ3224370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1V9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041928502" description="Sequence orphan" evidence="1">
        <location>
            <begin position="23"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="55133" checksum="BE68A94A61EB9BC2" modified="2024-05-29" version="1">MKSTILLLNTFLFITSTPFINSPPTPMRWDLNLIDFQNSFGQDKNFLVAEVSTVNQLDKETIVNVGEQPSTQPALPGEKAFQISFSCDVDATLCNKAKNGMHSYYLPFTFYSFVGFQSAANRIASVLRINTPIVVSATFKSFCEGADNCKLQGVLGQAAPSSYFSGKPAEASEDTQWMSYPSALIKQLRHSMDESAFAQFDITAQFNADFDFWFEGDALPMRPKQIDFEFVLCHELTHGLGFDTQWVQWSSVFKNVATSSNYLAPTLNAVGGVVESAKVASWLPMTVFDNFEYETSTLSSLMNRANSIYNFETIPNSLLTDTINAFERSTKEFTQAQYMFQIATQGSAAVTFHNPKKPLNDVKLFTAKTFQVGSSFAHFDYTSYFQTPDFLMIPAVSELSGKTLDDIINTNTKQGELSQKSCYGPLTLGVLEAIGWPTQQNPDSLAITIMTSSESIRGNGFYADPPVLQSSFKKHKVNFKLWSFLTLLIGFFCIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y207</accession>
    <name>A0AAD5Y207_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">N(Alpha)-acetyltransferase 38, NatC auxiliary</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NAA38</name>
        <name evidence="11" type="ORF">HK099_000937</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y207"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="348" mass="40236" checksum="01AC96A064217CE3" modified="2024-05-29" version="1">MTELETFQNKIVQVLTRDGQLVLGKLKGFDQTVNIILTESKLRNFSEEGTQEVQVGLQLIRGDNIALISEVDEELDDKINWESEAMVIANWNDPLDDVTWTTAAQQYSEIDETNPKSKRTGIFYLKLAAFFLATLRNVSATYISHLWAIGSGDKQWYIAHRIIVMLTWIMTFYLLYYRFAVTFRLSQKKSVLVGKFVLGFLVAAAIAECFGCLVMSYTDCWNIFEPALSIGVLLSTVYFDLYYMISLCFLFVHMKSNKDTVKAIKYLSSPLETMIVCLLYCITAWIYFLNTNTEYTWLTYFSNTWWNISWSLIPFIVIRSSSNKDIKKLTELKVQEVVTYKDKGYIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3P4</accession>
    <name>A0AAD5Y3P4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha 1,4-glycosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003345</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3P4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006688">
        <property type="term" value="P:glycosphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007652">
        <property type="entry name" value="A1-4-GlycosylTfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051981">
        <property type="entry name" value="Glycosyltransf_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042:SF21">
        <property type="entry name" value="ALPHA1,4-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042">
        <property type="entry name" value="LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04572">
        <property type="entry name" value="Gb3_synth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="7">
        <location>
            <begin position="306"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="7">
        <location>
            <begin position="380"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="474" mass="55842" checksum="00E7A9F4CE4A2B55" modified="2024-05-29" version="1">MQLKKKYKFFGKVFFLGILFSLIAVYCVAPHNKRVLKSKRKNSFDIKWLRSQFTLLNNFGVDSNEFEKIKTVDIKISESIENDNKEIKKLAAEDLKEKLKETVTCELEARKKPFVIYNGDGESFDFHKNSIKLFIKANLSVSPITEQLLISSVTQPIVVPKIIHFLNYNPTFETLPYLCSLESAAFHNRDHKINIYVMNVKDFNLRTEAWLNNIEFKNRLNVLELNFKEVFLGTPFESWYNMKEHLKSHWQYQNLGNAFRLALIWKKGGIYLDMDIISINSFKDLMEKRLVAREDSVRVNNAVLSFPPNDPFIWSSMEVFVNNFNGYAWANNGPLCLTRAIMRDCYWETLKTGKIDEFEKYTSDYDPQNEQISKNLLKFENFEKRNYCKSIDIANRSRFYPVHYSQSNFFTAPWTENCNLLKQIYKKSVGIHWWNRMFKFKKSKTELSPNSTLAKIFNDQCPVYMKQFGVKKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3V7</accession>
    <name>A0AAD5Y3V7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3V7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="307" mass="35396" checksum="2245921657C5F30C" modified="2024-05-29" version="1">MQTNLLVNKVKSTQPVFSGINCASTKQHNSFSPQSYNAEIEYFKAVNRSQFNEIKYLTQQVQFASTSREMGQRYLEELETKWNQLELSQNLSNPKILIANFHSVKTIDLDDIINDYIKHSPKDCKEFRTLDKEMVRNIQFVKSSVSQNELKNRVSQLTESENKFGSYGNGHNLNSQYSTVPSLKDHNVDYNTYHIFDLPKSYTSSLTVATPIKFKNSKFFRKYLGNSEIDLRMLFPNEHDDGVFFFNHKLFDLPSSYTSILRPAGPIKTLISNIYPNQVNLPTKRAISTSKDNSKNLTPKLQSNQVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3Y8</accession>
    <name>A0AAD5Y3Y8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar protease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PEP2_1</name>
        <name evidence="8" type="ORF">HK099_000418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3Y8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="7">
        <location>
            <begin position="41"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="283"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="464" mass="52570" checksum="F9ADEC99D197751F" modified="2024-05-29" version="1">MKRILNEDHKNLHSNDYSILEKRNLLKNFLISNNSKTLLAFLGQIEIGTPAQVIKSVLFDTGSFQCWVRSSECKLDVCKEEGMTSFNSAESNTYKDSGQLSEPVVYVDQSKISGKLVSDSVGVGNLKIMDFPFIEATFLSDNTLDGLVGMGLRSKDYPLFMNNLSNLTSEVFSYWIDENNENAELIIGGMNKNHLIGNLTWIYVNPYKKHWAAPINNSINVKNENNEVAAIKLPSNYYAVFDTGTSVNYLSLHLAKELNSYFNATVYLNESEKGGSVIYQIKCDNLYNLPEVSLNFYTQIFGNDSKDITLTFKGSDYILSFGNLCISTFFGQDGIFKNGENGILIGNALLKKFVTVFDYKNYRIGFGVSNRKKNKCYKSNFVFNKKDEVLFEFDNMGNESFYVNFVNCQEDELVGVFDLVVKSNLYFTPENLSEDSQRKSAAIPRCSVSTLMIVFFFFTFMFVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSK9</accession>
    <name>A0AAD5TSK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002283">
        <property type="protein sequence ID" value="KAJ3198713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSK9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3198713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="82" mass="9830" checksum="6525A2AB64D8168E" modified="2024-05-29" version="1" fragment="single">ELEENSEGEMEIVGKGKKEGDKIQINKNNNKDFVKEIEKLKRVKAKELHEKEVLKNKELLEKQRLEKEKKKIGTQKREKRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSZ8</accession>
    <name>A0AAD5TSZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001829">
        <property type="protein sequence ID" value="KAJ3200822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSZ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="62" mass="7785" checksum="C8353331EC73FE7E" modified="2024-05-29" version="1" fragment="single">NNWPHFGKNYYQIFDFEREQIWDQEKYEQEKILIRERASVKVDLQRIEFMVRNALRDVKLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU27</accession>
    <name>A0AAD5TU27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001756</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001529">
        <property type="protein sequence ID" value="KAJ3202725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU27"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="131"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3202725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="457" mass="52468" checksum="B6C3AF1EBB8098EE" modified="2024-05-29" version="1">MNLQSSYSQKPSCIPTTPTKHRYQLDDFAYLSPTKKFKCADSIPSLIGHDSELDEASSFSDLLDSSPLSASIDDHSICNSSYSNQYFLHPEHLNSSVSENTIDHQIEGTEKLAREAIRSALKTNKILTTNYCINLILGWGGNGVVIGGKSKLNNSNIAIKLIYKRDEKLNSSLPTLPNNLPSEIQILSTLNRKLNKEKINDSSIIKFIDWFEDDKNYYLVTSRIESNWNETNFFGDKIFEKEETLRTKNYFGETLTLAIRSGGSDLFSYIDSNTIVPINLQKVIFKQIAQGLAILHQNDITHGDIKEENILLNEMFQPKIIDFGHAKKRNYCKKKKTYLNKISFYGTRDMTAPEILINLNNKYNSDIPLRKFSGFENDIWALGLLLYAMCFGTLSSVDHKRFIRDCQEENFFGDYYPGKFFKIRDRNLTNLLKGMLTIDPKKRFNIFQVLDHPYLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU35</accession>
    <name>A0AAD5TU35_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001018</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001263">
        <property type="protein sequence ID" value="KAJ3204810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU35"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14812">
        <property type="entry name" value="bZIP_u3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="55"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="440" mass="50676" checksum="C9BA76DB8D34BD12" modified="2024-05-29" version="1">MNIFSTNSINQQIPIILPRPSINQDQDIQLSQFLPKKLAYPNSQTHHDKLNVDLEEKKRLRLIKNRAAADISRRRKREHLANLEVTTKQLEIENSNLKTKLSQIESANKEKEQMICQLQNKLNEFKILLETSNQKKNSNSEILNLEKINFSSDVSKKEERAGDLDFNEFVNFDAIDDYPPKLFTFENVNKEGCPYGTNDFEDSSILNDLKSISSSSLNSPVSSAFTDSPNSPPNTFLGAEINYNEDFDINTNNSGYSFGHVKTMFLTLFLSFTIIVNFNQNYTITSIKSISQSKNKENLHKVYEIEDKDFAPSSNNDPLSIKEVEIVENFNKILKTNNNNLICEFKENTIFKDVNLQRFLNKEGIESEENLIKSIEEKSLIEKPNFSLTLKLNKKNKQKYNWEKRKVNKIKFGEKFVLGSDESEKGFLILDLEIVGARIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUG4</accession>
    <name>A0AAD5TUG4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000699</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001175">
        <property type="protein sequence ID" value="KAJ3205793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUG4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140053">
        <property type="term" value="P:mitochondrial gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938:SF35">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47938">
        <property type="entry name" value="RESPIRATORY COMPLEX I CHAPERONE (CIA84), PUTATIVE (AFU_ORTHOLOGUE AFUA_2G06020)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3205793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="37564" checksum="0DF201EEC90325DA" modified="2024-05-29" version="1" fragment="single">MDSFFGKNSTSNYSRNTISKPYARDSSKITFPSNFSTEKKNFFKNQDASEEKLSSSFSRRVFNNETINIESDAKLKLSPRISQRENVIKKSKQDITTKKEKDENMMSTQFLDNTILESKNPKLHAATAYMERILNFKEEKLRESYEAYLNFIKKGLNFDIAINGKLLSLLAKFNRGTEINNIFKKMQKVDIKCVKIVLNYYTRRRDPEYSMKLFNSLPEMGLTPNQHIYYELIRVFANVKDEKQMLHYFNEIKNSLKEEPAIFNYNTVLNFYRENGNYDQIFKFFDDLKKSKVVTPNSYTYAVILNACFDNKKHLLAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV06</accession>
    <name>A0AAD5TV06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SWI/SNF chromatin-remodeling complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SNF5</name>
        <name evidence="7" type="ORF">HK099_002377</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001785">
        <property type="protein sequence ID" value="KAJ3201087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV06"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3201087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="430" mass="49886" checksum="09F893B676DB1C88" modified="2024-05-29" version="1" fragment="single">MTGQEFADVFPIANRKRYRIGREFVFTEKQCEEVSTKEEVLVPIRLDLEIDGTKIRDTFLWNQNDHVVSPDLFAEILCEDLKIPREQTLQFQNLISKQIKEQIEDFLNLNQSSVTVGSSHSKKRQRKNTNNISTPAMDSDISTSETPDNQFAFDLQDETFDDDKDRPELRILIKLDIIVGTVAYVDQIEWDINCRRNDPENFAKTICKDLNLSSEFENAIAHSIREQIHTYSKSLLLLDHKFDGSPIVDDEELAQSFLPTVNSIKKEMKLPLAPLLVEMDDSGMELIEKDLERLTRRKRRNQKSRRAITLPDREPQKTNRTRLPSMFEPIQEVKKPQLIEEMDEDNYFSGEEEVIRENTALTRAARGSRLTRATNVNETRIIDTNFKTNTKYDKIEVDLNTVKLVEKVWKCAKCDTTDTPIRRNGPLGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV48</accession>
    <name>A0AAD5TV48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001062">
        <property type="protein sequence ID" value="KAJ3207329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV48"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3207329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="405" mass="47399" checksum="A2FF4DF1D8553ECB" modified="2024-05-29" version="1">MSYKENTVTPSENSNYPVEKSPTSVTKDSDSITYQENLSDSNVFKVPGPITLSQIYSPKTNRFDEFPCDHPGCNKAYARADSLRRHKNSAHTVFKRIDLEKPLKLRDLDKKGRRFDRPFIYNNEQFQNYYTPPLTHPIKKEPIFVNLYSKRLLESQNCPMLFPIQRKRFNEEGDEIFPLKKESPVYPSELYTTMRKTDHDIMSKAELKKMAETTECLIPIKIEFEIDGENSLLKDCFVWNLNEKILTPEKFAKLMCEDLNIPTSKYSTMISSAIKDQVKEHVQFYLENDRPLFPDSRIFIELDLNFGTNTFKDRFEWDLTSDLEPEEFARILAQDLGFGGELVPMIAYSIREQILRSKIEDDIEPLARLQHGFREFLDDEIWSPTLIPLSEEYFDRMQGGDKIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV92</accession>
    <name>A0AAD5TV92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001068">
        <property type="protein sequence ID" value="KAJ3207256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV92"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042121995" evidence="1">
        <location>
            <begin position="17"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="248" mass="27719" checksum="940A112ED136BB59" modified="2024-05-29" version="1">MFLTFYFFGVFVLCSSLPRNTPSKDLIRSLPLGFLADPTIEKGCFSLYESGTYMFENGEFKEIPDAVNLSQNIFNRTLKHPEWKRAKENGAQFWIPILYDVAVDVIASKKIPGFKIEIGLSPSDALDVETVYNVRRILFKRDKEIHLPAGGALPMPQAIRIGQMRRNHFGPDCEHIVLRDHVLKVAVSLNLARGVIDVTQGASLALTETIVNWIVSGVEVFGNVISAEILVSGVHWGMVHFETEVTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVH1</accession>
    <name>A0AAD5TVH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Carnitine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CRC1</name>
        <name evidence="12" type="ORF">HK099_008385</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000913">
        <property type="protein sequence ID" value="KAJ3209994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVH1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015227">
        <property type="term" value="F:O-acyl-L-carnitine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902603">
        <property type="term" value="P:carnitine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006839">
        <property type="term" value="P:mitochondrial transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF4">
        <property type="entry name" value="CONGESTED-LIKE TRACHEA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="146"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="239"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="332"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="75"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3209994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="416" mass="45337" checksum="D36838ED1267A8A2" modified="2024-05-29" version="1">MYRSTTILLGKNIHTDTNFLNAIFEPLKGGVQEISTFDKDTLEASFMLQKGSIPGFDGTIFESLNIKEENIKKENGKNNLNSKTSISNSYTETEATSQKSSAVDSKQSNTTTKATIPKIKFSMKTLQKNTLEQDRKTENDIEVKKRKISINGIDEAPKKKKKKHPFDTVKVRLQTSNSYSGLIDCVKQTVAKDGLTGLYRGMTAPLIGVTPMFALSFFSYDMGQQLVYSLTPKRETKQLSMTEYAFAGGFSAIPTTVITTPMERVKVVMQTQTDNKYKGMFDAARGMFAEGGLKSLYRGSVATLARDVPGSAAYFVGYEYTATLVRPSDGSLSVPAELFAGGMAGVAMWSIAIPPDVIKSRIQAAPAGTYKGFVDCTAQMIKNEGPGALFKGLGPALLRAFPANGDKKLNQNNALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVZ2</accession>
    <name>A0AAD5TVZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001276">
        <property type="protein sequence ID" value="KAJ3204669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVZ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="59" mass="6699" checksum="89B20E80FEFD1E2F" modified="2024-05-29" version="1" fragment="single">LTEVTRSNNRFNCEAPECDYSNESPNAFGKHCRKCEKLIPWLKTGRNAVSINVVNVDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVZ9</accession>
    <name>A0AAD5TVZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_002469</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM U1 A/B'' family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001811">
        <property type="protein sequence ID" value="KAJ3200931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030532">
        <property type="term" value="C:small nuclear ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12246">
        <property type="entry name" value="RRM1_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12247">
        <property type="entry name" value="RRM2_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000039">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000029">
        <property type="entry name" value="U2 small nuclear ribonucleoprotein B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="9"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="167"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="111"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3200931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="26713" checksum="526FA1D7A93432AE" modified="2024-05-29" version="1" fragment="single">MNPTILPNDTLYIQRLNEKVKKPELKESLYSLFSPFGRILDIVALKTIKCRGQAFVVFEDTSCSTAALRSLQGFNFYDQPIKISYAKSTSNATLIKEGKFFPLLKKAKTETTKPVENAAETKKRARNDSDIEEDDSDMEEDDDDSGEPATKSVKVDEQSDESLPPNAILFLRNLPSDINEEMITFLFAQYPGFKETRMVPGTNGIAFVEFLTVAQATIAKSVLNGFNVTPKKRMVVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW27</accession>
    <name>A0AAD5TW27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">COPS4</name>
        <name evidence="13" type="ORF">HK099_007755</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000783">
        <property type="protein sequence ID" value="KAJ3212331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW27"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.780">
        <property type="entry name" value="von Hippel-Lindau disease tumour suppressor, beta domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037140">
        <property type="entry name" value="VHL_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036208">
        <property type="entry name" value="VHL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49468">
        <property type="entry name" value="VHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0736">Signalosome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="11">
        <location>
            <begin position="200"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="PCI" evidence="12">
        <location>
            <begin position="450"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3212331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="660" mass="74914" checksum="7D8B13A5F676E976" modified="2024-05-29" version="1">MQIKTIIHIIIIHIITINIALGATHNYLDPSNLLSSVPNSVNADTPSTLHIVNENDQTLNIFWKDYNGELVLYKNLSASESYHQSTYVTHSWVALDLSTNSVTHVFTVMEKEAIWVLLAVESNRNVNPSENLQVQEAEHNSDVVLIITLVSIILILLASSLLGFLMYRRIARKKKNNSAEQNTSDIMNSSESLPICDLIQNETTWKATCDFNKSLADELDMREGDLIEITSFFTDGWALGLNLRTNESGNVPLTLMVPARSEAELKDKISIFHKYTLTLLEQKNLSKTKEIIDNLLQDSHGLILTRQLLSDFVNELKSFQSNNSSDLEVKTEISKIWEYTLEKIGNKATAFEESISIIREELAAIYEDEERWTDSARMLQGIPLDSGHRAIPDEYKLKIYIQIVSLFLEDEDPTSAESFLNRAGLLVQTTSNKSLVIRYKANQARLLDYKRMFLNSAQKYFELSNMEEVLDEERIMCLRNAITCSCLAPAGPARSRMLATFYKDERCRERAELKEGNLYGILEKMYLGRLLRPNEILDFSKTLKEHQKATLSDNSTVLDRAVMEHNLLSLTQIYNNISFKELGTLLDISWEKAEDMASKMISEGRMKGSIDQLDQLIFFTSGKLLDGGWDEGIVGICQHLDGIVEKIKVKHPEFANLHGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWG8</accession>
    <name>A0AAD5TWG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001363">
        <property type="protein sequence ID" value="KAJ3203910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWG8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00177">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF14">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="1">
        <location>
            <begin position="30"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="350" mass="39208" checksum="FC0FF1C8213A7672" modified="2024-05-29" version="1">MLAAEPNTTIPDIKAATITLFNELLVSKKWTYSHTHKDVNIALADSPSNFSLPIIKGDAFFTDQFTKLEWLSVANNPEARKFWDARFDGAEVLEAIGEGDLIIHSIQKGQLMVSARELLTLTTQYYGQNGDLCYFAVSINGHNKYVSGKGKVLANLGIAGWCFSSETRDGVEGLKVTYMVDVNINGYVPSSLIKIVQAQTPQCVETVHNYLTKYGTTAFLLKTLPEDSEFRLKNLIGLREKRNSKNEDVEVNMKVVDLKKNSLLSIYIPDKKSFKDGFKVENLNFKNKVDVKFVKFEKDKKEFKDLVSKSCLGFLVLDIAVGELENLEFVIKSNTGGNSYLFDGKQVNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWP3</accession>
    <name>A0AAD5TWP3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000675">
        <property type="protein sequence ID" value="KAJ3213799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWP3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="273" mass="31792" checksum="417BA2F6B8BDAF7A" modified="2024-05-29" version="1">MENIQHIEPNYFIPTLNLNNSHNLKFAQYPTAIPQNKKKKSLQFFNLNNSFKKEEINFGLDVATFDMNKFESFLCVVEYTLLGYCPSTEKNEELIDFMEIDISGVDMLKRDIDNAMEISDVNKGAMVNVTPSSSASPDSSHQDSSLDSNYIKSVRRNIMEDQVLRKEDEDGKVFYVCNLVSCPKYNVKVKRRGNMLSHLKTHLPLHVRRTIRCPQCSNYFSSMEDLKRHIKSIHGEIEIKCSYCEYVDKNYRRVKTHEKTCKEKIEIADLSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXA8</accession>
    <name>A0AAD5TXA8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CLA4_2</name>
        <name evidence="17" type="ORF">HK099_006694</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000598">
        <property type="protein sequence ID" value="KAJ3214708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXA8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13279">
        <property type="entry name" value="PH_Cla4_Ste20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000139">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000705">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.810.10:FF:000005">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="13"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="15">
        <location>
            <begin position="421"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="13">
        <location>
            <begin position="535"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="16">
        <location>
            <begin position="633"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="852"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="698"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="698"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="716"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="742"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="776"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="881"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3214708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1115" mass="126100" checksum="1F24A69B5F18FE5C" modified="2024-05-29" version="1" fragment="single">MMKDDAMDEDFTAEELKQKGNALYKIGSYRQAAEFYGKCIEMEPKNPTYYSNRSAALMMKGDFKEAIKDAKTSLLYDSDNVKVYFRIAKCNVSIGNVAEALSQLQYCKSLNCGKNNAAVDKEINSITKVSANLIKYAKLFNDGNWEDALQILDQCCLLVDNGLYKKNFSFIAGNSRLSDTDLVNIPVKWRLMRAECFVKTRHLDEANSISMKILMDDKTNSDALTIRAEVQSLLESHPTNAIQSLLQNALAYDPDNKNARNLNKKIKQREILKKEGNEAFSSQNYALAEEIYSKIIDGDEDNAMMKVKVLSNRANVRSKINKFLDAIKDCDEAYECLENLVFPKTGNSDPNPSAADIQSSVHLSMFVKIVLRRADCYNKVEKYEECVRDYTFASSIQPDDKQIKIALKSAKETLRISKRKDYYKILGADKDSSEKEITKCYRKQCLIYHPDKQVNLSEDEKHLATEKFKEVQEAYTVLSDPRKKNMFDQGMDVDGSSASDGHQHHGGDMSDIMNMFFAQQQGGGFGGFNQQHGSYVVKRGYCSVKEDGIRSFLWAKRWLLLREQTLTFHRNENTYQALALVFLKEIDAVNRTDHKPYCFEIITKDKSYYISCKSDEELYSWIDELYQRSPLGISGPTNFVHEVHVGFDAHSGLFTGLPKEWKSLLDSSNISKEEMSKNPQAVLDVLEFYTENMTSDMLKNERDIPQKDTRPYNAQSSSATTSSSSSTTLNNSNSNQKKDIYNNSNNNNNYVNNNPSKSDNNSFKDLSLNNEEVRTAPPPPQRPAIVPRPPHTIEKGQQPVQPPPPKEKTPENSPQPAKKKPQKEPRMSTMTENQIMEKLKNVVSKNDPLTLYAKIKKIGQGASGSVYVARDTQKGGMVAIKQMELSAQPRKELIVNEILVMKESQHPNIVNYLDSFLVKGDLWVIMEYMEGGTLTDIIDNNTMTESQISAICFETIKGLSHLHGRSIIHRDIKSDNVLMDADGHVKITDFGFCAKLSNDRNKRATMVGTPYWMAPEVVKQKEYGAKVDVWSLGIMAIEMIEGEPPYLEEEPLKALYLIATNGTPTLKTPDKLSGVFKNFLGRCLEVDVTKRATSEELLQHPYMRLAAPFSALTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXP1</accession>
    <name>A0AAD5TXP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000875">
        <property type="protein sequence ID" value="KAJ3210751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXP1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3210751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="80" mass="9258" checksum="67F5F91DFA2D34F6" modified="2024-05-29" version="1">MMVLLEAPGRRLELALYCLPRALESLWNCLVKKGVLRNIRNGELIYFSLSMGVIMTLYQHDPESINDAYRNLMVRFLGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXV1</accession>
    <name>A0AAD5TXV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006934</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000632">
        <property type="protein sequence ID" value="KAJ3214322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXV1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50202">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="MSP" evidence="2">
        <location>
            <begin position="7"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="242" mass="27594" checksum="F442D7A959D30663" modified="2024-05-29" version="1">MDKQLQLIKLNPPHFYFSTNSKYKMSGTTLLGKITVQSNSANPIGYKFKTNAPARYSVKPVLGVLEPHCSINILVRTEGNINATDRFLIQTVSLTSDESLIINSNTWKQLDRSRLYENFIDCKIDLNNNFNKSNSSSPSDKPIPNIYALGSPRSTTKSTASLLKTPSGTPQKSNFNNKNFTNNNFQKQELLHNKNLKFYERNFIQKFSINEIIIFSLLFFITGIFFPYQKLLFFNDSLHAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY11</accession>
    <name>A0AAD5TY11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome c oxidase subunit 6, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytochrome c oxidase polypeptide VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">COX6</name>
        <name evidence="12" type="ORF">HK099_006672</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Peripheral membrane protein</topology>
            <orientation evidence="1 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cytochrome c oxidase subunit 5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000592">
        <property type="protein sequence ID" value="KAJ3214786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY11"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.40">
        <property type="entry name" value="Cytochrome c oxidase, subunit Va/VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003204">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036545">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200:SF11">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02284">
        <property type="entry name" value="COX5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48479">
        <property type="entry name" value="Cytochrome c oxidase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3214786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="159" mass="18911" checksum="D668C884F173FD32" modified="2024-05-29" version="1">MFRQLALTSKFLKPKFKLTSNISIIQPTTLVHKFNQRHYSSELDPSEKKDYAAYVSQWKEHFKTIDDDWELERGLNHIFAADWVPSLDVIEEAIRASRRLNCFATAVRVLDALENKVENRKQYDDYLTHLNPLLTELGVVERKEFGKFETVRDKTKWWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY45</accession>
    <name>A0AAD5TY45_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001814</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001558">
        <property type="protein sequence ID" value="KAJ3202528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY45"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF58">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="158"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3202528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="28707" checksum="B3AC5CB523159E42" modified="2024-05-29" version="1" fragment="single">VAVGHPFDTIKTKMQAEPGFNNGMVKSFQQVWNSQGVKGLYKGSLGPILGSGLYRSTQFAVFEALYTKWDNQFMKKEIPYTFGLQNRVVLAGFAASTARALIECPIEYAKVCRQTGQNWNFNQIFKGFHWQWVRTSGVMVWYFCAIDSIRRNHPEVFSSPSGQFLASSTVATLGFWIVWPTEVLKNQVQAGTKIKGKTSAISTMDRLNDLMKNHGGIRGLYRGILPGTYRSFFANGFSIVVMIWAQKQATALGFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ00</accession>
    <name>A0AAD5TZ00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">vesicle-fusing ATPase</fullName>
            <ecNumber evidence="6">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="primary">VPS4</name>
        <name evidence="27" type="ORF">HK099_005823</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endosome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the EROs family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000471">
        <property type="protein sequence ID" value="KAJ3216566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ00"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02678">
        <property type="entry name" value="MIT_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19521">
        <property type="entry name" value="RecA-like_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.80:FF:000004">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000043">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000015">
        <property type="entry name" value="vacuolar protein sorting-associated protein 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045253">
        <property type="entry name" value="VPS4_MIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF83">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="20" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0967">Endosome</keyword>
    <keyword evidence="14" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="21" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MIT" evidence="26">
        <location>
            <begin position="304"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="25">
        <location>
            <begin position="468"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="382"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00048883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAJ3216566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="744" mass="83878" checksum="F47C40C3AEF560F4" modified="2024-05-29" version="1">MPIFLLKIFQSQIPEEWECGKSIGDVDFSNNNFGSSQNVIGSPFIKCDYTTKDFCIIDDESSLSDGVYVNLLKNPERYTGYDGEAAHKVWSSIYNENCFNSHFSTASMPNLFDRNEDTTQCIEARFADVDCFVNRVGLYPERVENMYFLYAVITRALTKLIPYLKTYNFCTINNGKSDETNAESCPTTFNETLLFNSMNSQELKNEFKEHFRNVSRIMDCVTCEKCKLWGKIQTSGLGTALKVLFSYGEKLHGIALTRGELVALFNTFHKVSESINAKNIFDNMLHEKANKQWILAEIAAEKKLLDSVKKAIEIVRKATEEDAKGNFEEAYKLYQNSLEYFLTAMKYEKNEKVKESVRKKFTEYLDRAEKLKEYLQKTNKKKAIPNGLSNEGKNKGESESEDEVDEDKKKEDAETKKMRGALSGAILSEKPNVHWNDIAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMGESERLVKQLFAMAREQKPAIIFIDEVDSLCGARGEGDSEASRRIKTEFLVQMQGVGHDMTGVLVLGATNIPWQLDPAVRRRFERRIYIPLPEVNARSTMFRLNIGSTPCQLSQNDFKILGERTKGYSGSDIAVVVRDALMEPVRKVQLATHFKQVQGPDRKDPSKIKTYLIPCSPGDAGAIEKTWMDVGAEELMEPPLVVSDFAKAVQNSKSSVNDDDVAAYTKWTEEFGQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ27</accession>
    <name>A0AAD5TZ27_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005748</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000462">
        <property type="protein sequence ID" value="KAJ3216762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ27"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF22">
        <property type="entry name" value="GLYCOSIDASE CRH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042278590" evidence="7">
        <location>
            <begin position="20"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="8">
        <location>
            <begin position="20"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="9">
        <location>
            <begin position="102"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="365"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3216762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="425" mass="44900" checksum="223688FAD2AD23E4" modified="2024-05-29" version="1">MSVVKKSLLAILAANLISSQLNCGINNAGAVCGTTSPCCSEYGVCGTTSLHCGGGCQSKYSSPAGLNSENAACFQDRPSVKSQKCKSGVYDFGPSTWIVNTEAWNGDVNQADFTIDNYQNQTENIEIVQGATKMWLRPTSQTTVPGMGVRVSSTSYLNYGFFSVKLRGGSPPGMVTSFISMSDVKDEIDWEFTGGDRLNGQTNIFYKISEGGAIDYTNGARFPVPDWSTTTSEYGVDWSESKIDFLINGQVVRTVLASAGNFPNTPSRIQLAVWDGADGQPEGTRNWAMGGPGFIDWTAGGSQGYYATIEQITIKCAGDTTPTGAPERPAGYTAPTLNNKAMKIAVNGLAGSDYFKIGSALNAAGNSSSSSTTTDSTDSTNTSTGSKATNSTSKNGNSKSEGFKIGTLSNFALFFGATFFYCSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZD9</accession>
    <name>A0AAD5TZD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Myosin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006953</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Binds to cdc4 and rlc1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000637">
        <property type="protein sequence ID" value="KAJ3214245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZD9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120104">
        <property type="term" value="C:mitotic actomyosin contractile ring, proximal layer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902404">
        <property type="term" value="P:mitotic actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01377">
        <property type="entry name" value="MYSc_class_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.530:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF857">
        <property type="entry name" value="MYOSIN-11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 9" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="10">
        <location>
            <begin position="1"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="9">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00064372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3214245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="657" mass="75242" checksum="4373A701ADDCC64D" modified="2024-05-29" version="1">MPIYSDDVVKSYKGKKRSEMAPHIFAISDSAYHAMLTNRENQSILITGESGAGKTENTKKVIQYLASIACSKEYSTQQLNNGEKNATLEQQILQANPILESFGNAQTIRNNNSSRFGKFIRIEFNATGHIHGANIERYLLEKSRVTHQTLKERNYHIFYQLLKGAGPELKKKLLLGNDLNEYAFVKNSNKNIEGVDDVADFKSLQDSMEIMNMKSNLQEDFFRTIAGILHLGNLTFTADREDQAQMNEKSQQVAEKVCHVLGIPCGEFVKSLIKPKIKAGRDWVTQARNVEQTNYSVEALARAMYERMFGKLVDAVNTALYTPMTKSTFIGVLDIAGFEIFELNSFEQLCINYTNEKLQQFFNHHMFILEQEEYKREGIEWKFIDFGLDLQPTIDLIEKSNPIGILSCLDEECVMPKATDKTFIDKLNGLWKGKSSKYDVPKFNQSFILTHYAGKVEYSTAGWLDKNKDPLNENVTRLLAHSSEKFIAELFSDYAAEPEDFNLKNARAANVKKGAFRTVAQRHKEQLTSLLSQLYSTEPHFVRCIIPNEEKKPRKLNVNQVLDQLRCNGVLEGIRICRAGFPNRVIFSDFRQRYEVLTPETVPKGFMDGRKASQLILEKLNLDKNQYRIGNSKVFFRSGVVSEININIFKRIFHFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZP4</accession>
    <name>A0AAD5TZP4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_004868</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000359">
        <property type="protein sequence ID" value="KAJ3218938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZP4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF0">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="468"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3218938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="481" mass="53357" checksum="54EAF5DBB25A36B7" modified="2024-05-29" version="1">MGLKSIAYNHCVKPFIDLHRFFVESGKKVGLLFVIITAGIYFLQGFRAYALGDGITWMFEEEFKLTPGEITNVDSTINIPWNIKMIYGLIFDSFPIFHRHDQPYLFLAAALQFMGFLGIAIKPWSSTATAATAFFFMFSMGIATTDVLADAMIVKKAKQLGKAGGADFQTLCWISLQVGTLIGTPVSSTIVGDGAGARNLYAYVYTTTAGLVFIAAFFLTEKPSNIRTGPKYLFNQIRVLLKAALFDMKIFLPILWILLNGALIADLSAPMALWKKQEIKISPAVQGYLTMGGTISAIVGMLLYARYFKETPFRKILFWTQFFLGVVSFFDIMLVKRWNVAIGLPDLPFLFGGRVITYAITYLQQVPFLVMAAQLCPDGIEATFFATLMSCSNGGGNIARKWSAVLIEALKMEPKEVNGKDVIDFTNLELGLWISMGGVFLGGLLVFVLIPNTAHIFPEKEAEDEAREEYGLEKEKGDQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZT5</accession>
    <name>A0AAD5TZT5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transketolase-like pyrimidine-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006551</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000573">
        <property type="protein sequence ID" value="KAJ3215053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZT5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="6">
        <location>
            <begin position="937"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1214" mass="137065" checksum="DE9A8F96CB263627" modified="2024-05-29" version="1" fragment="single">MKNLITKCLWEDCNLQFLTEEECYNHYSDAHIVTGVQKCKWNSRGRGFEPCNLNFQHKGHIRDHSVVHFSSIYPKQCTFCGERMKNRQNLHRHKTRFCKKINYNDNQIPKKKSNNKSTPVVSSTTYTQDSNNATNFQTNLALSPLTSTIMNFSQLPSSLPLSPTIQTTLFSPIPPTITCLSPIRTKPVHLSPIPNSQKKNISALSFNQQCSVPINPSLLLSPDQMCSSNLSSNLSSVSTVSPAQQFNNSLSISALSSAQMYDPAINSNLSSLSPLSPVQQNTYSLTPTSPNIENKLNPPKILFENMNYNENLLSVPLKDNGGNNTNVLKNMWNIDESIKNWKFNTMSGVNGSRIVDSNSKNSIKSDELLFNEFYKTFYTAPNSVDNDVFGYRIPKEWALEPYTQEQLDNRNANANLLRLVKAYRTKGHLQADLDPLGLAKKEEIPELDPKYYGLNDPNQVFDLNGIAHISKTKRDTDPLEEATLEKILKQLNRTYSGRLGFEFEHIPNTSERRWIAQQLESQERKTLKKEEKMDIFNLLTKSEVFDHFMAKKFPAVKRYGLEGAESMMVALDSLFKNSNIGNIDEVVVCMPHRGRMNLLTGSMNFSPTQLFHKVKGNSELPVGTPGIGDVISHLAKSVDLDFKHGKSIHVSLLHNPSHLEAANPVAMGKTRAKQLDLLKKGTAGSGCSLGDRILCVQLHGDSAFTGQGVVTETLGLSNLPHYCCGGSIHLIVNNQVGYTTTPMNGRSTVYSSDIAKMINAPVIHVNADHPEDVTYAMELAFGYRQHFKKDIIVDLIGFRRWGHNELDEPAFTQPLMYKIIRNRKSVPTLYEEKLLNEGVVSKEDIVKVRDAYFEELTNHLEASYTFKPTVDFCQGKWKDMIIPTHVDNSVSTGVDINILKEVAKKSVQTPESFTPHPRLKKYHIETRIARAEEGTKLDWATCEAMMFGSLMKEGYDVRISGQDVGRGTFSQRHVMLIDQDTEKTYIPLNQMSPDQKAFLEIANSHLSEFAVLGFEVGVSWENPNRLCIWEAQFGDFFNGAQIIIDTYLSSSESKWLRQTGLVMLLPHGMDGAGPEHSGCRMERFLQLCDQKFDVLNTEKIDNPNMHVVNPTTPAQYFHVMRRQMTRNYRKPLIVVGPKTLLRHPQATSSIEDMGPNTYFQPVLGDTICEANPSSVERVIFMSGKLYYDLIKKRNDMNLNERVAIIRLEELCPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZT7</accession>
    <name>A0AAD5TZT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Berardinelli-Seip congenital lipodystrophy 2 (Seipin)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">BSCL2</name>
        <name evidence="8" type="ORF">HK099_004764</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000347">
        <property type="protein sequence ID" value="KAJ3219231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZT7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23995">
        <property type="entry name" value="Seipin_BSCL2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212">
        <property type="entry name" value="BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212:SF0">
        <property type="entry name" value="SEIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3219231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="410" mass="48388" checksum="8789A42CF7E2A70F" modified="2024-05-29" version="1" fragment="single">NIPLINQQIKDNFQELKQNPFLNEVKNVGLDIKENPYPYIESTRRNITTFVEDFHLPQEVVLEAAYKPVHDTVYPRLRPLLNTITNPETQKKILNRIIFFTMFVLLFSGALLMYTAFYNMYLPTFERSLDVYMDYDHHNGYFKTYFSILKKISLNISVFAQVDLSIPYMDSNERFFKDKERFDLKFDIEIPESDANFLKNNFMVTVTTFDNKNETLKGSTRPGLVRHKSHLLRYLNTLSKSFFLVTGLLEESQVIRVDLLENCFEDTYNPTKYATLKINERNLQIYSTKLTVRKRLQGLAYLMVNRWFITGSVFVLIFMVLETIGLYFLYLARLLKKKYFVKEVQEYEDGDMVEENSVNADPEYKTFEIDTKAEIDEFFKKKFVDDDYVDDTKDDEDAAVPDLNTLESIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZX5</accession>
    <name>A0AAD5TZX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000555">
        <property type="protein sequence ID" value="KAJ3215270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZX5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1071" mass="119017" checksum="E46FC2F8A526AB04" modified="2024-05-29" version="1">MDCSFEVQALQMMKNIAQPNSLEVEKKTENNHHQFKESTFSVTNKPDDNLTKAKKSYDVIMTEINTNNSKLTSTLLEITNNQNQHISPSANCAHNVFLNPVFSSENRLNENSNQTFSNATNNQLNPIVTQQPIPIQNQISSSVWMHNTPTTAQSSQTQKLLFTSHNNFNLSAPDMINSSLPQPFSNNNQSIPQQLPTTYIPSYPVVSTNNYSNQQILSTLSQIPVTSQQYISALPDQFPVTTQHFVSATTQFLSTTPQYVATTAEPLPTTTQYLPTTTLIIPTTQFNPSTTQYVTSAPVTQFMATNTNSHHPTVSHLLQANNVPTTLTNQQFSSSVSQFHPNTTSFVTHSNPTLQLHNTNTNEQYLLSTSSKSLPNYTSAIQTSSIGSTPSFSQDQKESPASLSNKQIPHSLLSNQSNTSISSQPNSLVQSQPNSLGQYAPAPMSSASFLPLIPNVNNTILNQNSVVLTTQPQNIANSMLKVDANNSFTHPVISSLEGQSVETQSTYRNTQPPTSSKNLSTAVAALVNNNPATSNAIVTAVAQVVAEAVRTAVVQQQIQINQQVEIQQEQVFQQEQIIAQQQAHIQAQQEQIIAQNTFQICQEKALEEATAASEKAQMQAINTMMINDQIQQQFGISPSLLTQSHEAEVSVKKEVEATNSEENLVKPENGNSAEIDRDNEVEENDSDGALSDGNIEEDEPMEKEVLDFAKLEENIDSRAFDAAENIPDIFETSVFYLYKIIRHKLYKPMYRTQADYGLKRWGLTSGRLCQILGCEPILRTLADFERRPHCEKVCRTLQSCVKDSSPMISLPQLWSRSLLECTEEKVVSSTVIMKAHKTLMEIEKSSFASSKDDMKVDKKRNSGHDPLQYLEFNVPENLAEHISDFFNGKLSIDPLWNPSSFINPSRKFFINNDIIADPLNESWVDGSLNCSCFLPLIDSSNDYSFAQKYYEKLQEEIANGHVKEALVLAVYDLSIPWVRSALEKSSSVFLFPQKFVPLSGKISVSIKKRTRKRARLSSSSSSSTSVNSSSSSPDDDGVGYCLIYQGPRNQKFYNKFKNFGLCPGLNCPSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZZ7</accession>
    <name>A0AAD5TZZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007498</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000730">
        <property type="protein sequence ID" value="KAJ3213251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZZ7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="167" mass="19346" checksum="6E30A51ED1C61DA3" modified="2024-05-29" version="1">MDGKLVLNISSTSNTALYRVSKHFSNPFVREDPISKSFQNNEVLWLDSTKRVVSQGCCQIHSDDKKAISLLPEKDISNYNYLRTVFAHQLDMTQVITDSPLLLTRDGASENSHHSLMPLLEIPTADYLDSLLQLKWLETKEYSMIWNEDQQIWKMEFVKNIIQQNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0K8</accession>
    <name>A0AAD5U0K8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">STE20</name>
        <name evidence="18" type="ORF">HK099_004163</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000289">
        <property type="protein sequence ID" value="KAJ3220590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0K8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030447">
        <property type="term" value="P:filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000011">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000385">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011026">
        <property type="entry name" value="WAS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47912">
        <property type="entry name" value="Wiscott-Aldrich syndrome protein, WASP, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CRIB" evidence="17">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="354"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="211"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3220590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="632" mass="69927" checksum="985B513078FEE34A" modified="2024-05-29" version="1">MNSNTYSNDGEKPQNESSQKERVRKVPPRPENTTTPQTLVTRERQASNTNNTTSSDSLLNQDSNAQLQGNSLEYALIPTATAQSLSSSSEKGEQSKTMKGLLSNVISSVQGVFNPQVSKVEISNPYNPVHLTHVGYNQDTGEFTGLPREWETLLQQAGITKEQQQADPQTVLEIMEFYNETNNLSPEDSSVWSKFGNVNVKNENYLGTHNLERGLPSSKGSEISLPSLTGGFSSSQTSLHHNNLSDKKRPAIPQRPAHTMSIYSTDIKADAKPSEKIIPPQKPSRSQDKLDQPRSTSTSPKTSPKPSPSLPKKTNLQSVDNNQLRPRPKAALSMEDVLAKLSTVCNPSDPTKYFRNLVKIGQGASGGVYTAYQVGTNNSVAIKQMNLEQQPKKDLIINEIIVMKNSKHKNIVNFIDSFLWKGDLWVIMEYMEGGSLTDVVTSNFMTEGQIASVAKEVLEGLKHLHSKGIIHRDIKSDNILLGLDGSIKLTDFGFCAQIADSNSKRTTMVGTPYWYDFAMAPEVVTRKEYGPKVDIWSLGIMSIEMVEGEPPYLNENPLRALYLIATNGTPTIQNPESLSAVFRDFLKVCLEVSVDRRPNSNLLLTHPFIAKADPLKNLVPLIKAAKKEKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U107</accession>
    <name>A0AAD5U107_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_003938</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000267">
        <property type="protein sequence ID" value="KAJ3220874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U107"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042592">
        <property type="term" value="P:homeostatic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18595">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000450">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000001">
        <property type="entry name" value="ATP-binding cassette subfamily C member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000074">
        <property type="entry name" value="Multidrug resistance-associated protein 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="666"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="720"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="798"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="50"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="347"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="667"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1000"/>
            <end position="1234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3220874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1239" mass="139136" checksum="677541C567C7D1FB" modified="2024-05-29" version="1">MEDLWNLKKSDTASYNSEIFQNAWQNETRKKNPSLVWALCAAYGPVFLSAGIFKLGQDSLAFVQPQLLNQLVAFAKSWSTDSKQVPEPLAKGFFIACLMLISAVTQTILLHQYFHITLITSLRIKSAITTAVYKKALTLSNDSRSSSTVGEIVNLMTVDAGRVADLLGYLHILWSGPYQILLALYFLYAALGPSIFAAQMKNKDDRTKLMDELLNGIKVIKLYAWEIPFKKRVTKVRDAELDGLRKIGFLAAAQSFTWACTPFLVSFSTFLVFSIISEEKLVSEKVFGAIALFNMLQFPLNVFPNVISSLINATVTFERLFKFLSAEELDNNAVTCERVYSGPINRVEIKNASFYWTKPSENTDLRLILKNISLDCTDKTLIAVVGSVGSGKSSLINSILGEMYKSSGQVILRGSVAYIPQNAWIMNASLRENILFGKRYDEKFYNHVIEACQLRQDLDILPGGDLTEIGEKGINLSGGQKQRVSIARAAYFDADIYLFDDPLSAVDQHVGKHIFDNVIGNNGLLKDKARILVTHGIHFLPKCDRIISLAEGEIRESGTYSQLMKNETYFYELIKTYGKKKDVTNATDSPTPNADDAKIALEKALVVKNKGFSKEKETELMKSLNIAPNMAITPSNLIILKEEGAKGSVSWSVYKSYAESCSFRSVVLYLIILFLTQASSVFQNVFLADWAHSNDKIKKKISISYEDNDNGMSDEVIWRLGVYGLLGIVFSVSTVLQTIFIWVYCGMRSAKVLHQQMLDNILKLPQSFFDTTPLGRIMNRFSKDQNTIDETLPRTFHGYFRTLFSVLSVLAVNSFSSPLFLVFAIPLGYLYIFFQRYYISTSRELKRLDSISRSPVYAHFQETLGGLATIRAYKQEKRFLATNEDRVDYNQRAAFPSICSNRWLAVRLEFIGSLIVFGSANFSVVSILATGTVNQSIAGLCLTYSLTVTQTLNWMVRMSCDIESQIISVERIKEYMELPNEAPFKIEGVNPPRDWPNGKIEFKKYGCRYREGLDLVLKEVDFQVMPREKIGIVGRTGAGKSSLTVALFRLIEPSMGTIVIDGVDIRILGLHDLRSRLTIIPQDPFVFSGTIRENLDPFEEYDDSTLWKALESASLKTAVSKLDKKLDALVVQGGENFSVGQRQLMCLARALLRKTNILILDEATAAIDVETDNVIQQTIRQEFKNCTILTIAHRINTVLDSDKILVLDQGKVTEFDEPKKLLEMKNSKFYALAKEAGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U111</accession>
    <name>A0AAD5U111_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Resolvase/invertase-type recombinase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000758">
        <property type="protein sequence ID" value="KAJ3212911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U111"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="272"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="715" mass="81214" checksum="9F90BDDD0BDD6165" modified="2024-05-29" version="1">MQFELERSENVTAAQEWQSQRVDRKTGSHILPIHAGDLWNPRHWPRLIASTNDNKKITPLQFTLMSTQKVDEIIESAYRNLQLGELDANILTRWKLLGEPVVERLKGVFDYLQKKCPVGEPLINRLQESNALIGIPSKNSFKNCRDHAIWISTNCFFFLNPPYITFKISRMVAGISNILIIPNILFSESSLQTAFMKDYHLNIGLENLRIEECPIDFSNLFRNDGRLKYTQNLLHVLAPFVQNVLYRSPVTWSNLSLSSVSELNSYAEVKQLVLYVRVSTNKQQQNLIPITRQIFSLVHATKSLGLQPIQISTIIEIASSHELPAVSRVAIRQLAHIASKVASNEILVLTVNPDRLTRRFYEIKSFSKRFRWLSSGLGNDTSSFVDIAEYQDKASAQVALGEDMASQHGLYSRYYLMYCRILFAVQSPQHNIAIKTTGDVVGICRTSPHFSGASSSSLKTQRALLKSFFSDSIDIQTIEQESAWSGETRKIILSRGFSHHCYAAKKNRNKLLGLFWPPSVVNVALKAGIRADEIVYYNEGVANQNYLKEMLDIPKINPPLYPIYIQEQRGALLDGIEHCIREASNFIEGFQTSSYQGTSGPLPLELQVPEKVASTRGMQKKHKKKFEQYIEANFPESLQNIYYFDSRTCKAHCYCTIAHTYHDSEVCVCSCIYCSTQREDACKCSDLCTCPPYCPCTCKICHVEKLVEPVKEVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1E0</accession>
    <name>A0AAD5U1E0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000263">
        <property type="protein sequence ID" value="KAJ3220918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1E0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="595" mass="68726" checksum="6A40B87C103F67E0" modified="2024-05-29" version="1">MTIYNNIYLTSNQIQLSKTLLTDTSPLLIEFTTSYIQLLWNNISLNQSVFNPNKEFQLFVKDILNKTNLCFSVLLISLKFISKLKKFNPGQVGQGSECRIFICSLMLSMKFLMDNSYTNETWEKVSNIPISQINKAEVEFLVQIRFDLNISEKEYAYWLIDIEQKVKEYILIFENQKILKEDLKLKELFFYQQQQKHQQEKQKQLSQRNIQSQLFNHHPSLPLQKQQLLYSPGTSLNSSPANNQLHQQILQFNRNNSLQYNQVPNNIAVKSDSPLSSCSINSSNSPSTATPKSFSHSNYTKIPRSASHFNDLSNSAIQNDNNDSNLNSFNSLNVSSNNHDMFMCNNISNPSPNLALNNMPQQLLQQKAVVTQQSQQDLSGNLSKNYLLEHQKSQQLNQIRQQKHQMIPSDATQISHPLTPTSTLSVDQQNYIPQIKQHQAPQSINSQLLLQRRQPQFQEPSQLQHSNHPFLQQAPTSRPISLDGSLHHHNRQKFVPLQQASWENIPDQNRSRDSLPQSGRYFTTSQQHNHSAAFQQQPISQLPQHSRFVQPLLENNFVNINWNKPSMAEFLEKPSRITPVIEFNYYNPFPNFGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1E6</accession>
    <name>A0AAD5U1E6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000263">
        <property type="protein sequence ID" value="KAJ3220920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1E6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="71" mass="7847" checksum="16521745C2DD6C35" modified="2024-05-29" version="1">MSETQPKPPSSSTNSIVQPLGARLSTLVLKTHGTPQLSRAYLQRIMMDENTQYLLLAVVWFTSPPVFGTIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U278</accession>
    <name>A0AAD5U278_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003257</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000216">
        <property type="protein sequence ID" value="KAJ3221666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058565">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058567">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058568">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058564">
        <property type="entry name" value="TPR_TRAPPC9_Trs120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013935">
        <property type="entry name" value="Trs120_TRAPPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058563">
        <property type="entry name" value="Trs120_TRAPPC9_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512:SF5">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26254">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26280">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26282">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26283">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26251">
        <property type="entry name" value="TPR_TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08626">
        <property type="entry name" value="TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trs120/TRAPPC9 N-terminal" evidence="4">
        <location>
            <begin position="13"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 TPR region" evidence="5">
        <location>
            <begin position="378"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 first Ig-like" evidence="6">
        <location>
            <begin position="758"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 third Ig-like" evidence="7">
        <location>
            <begin position="1228"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 fourth Ig-like" evidence="8">
        <location>
            <begin position="1391"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="903"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="906"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF26283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3221666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1515" mass="170452" checksum="E83CB791E596DDFA" modified="2024-05-29" version="1">MKKSLNISSTKLNLLDDARIRIIVIPIHPIRTETFKKYLDCITKFHQVYIGDLNPPHKNTNKYTEKLYHSGHVNFNFVTSYNKEHQPLEDFQLNKQIFGIIGIMHCQQVSSLTDGYKKFKQLSTRYPTSLTSRCFAFEPSENQADDVKGPIMIPNVGHLDFYLNTMMTDFSSELLGALGTFATQIEKRNLISGPIMISPLNVNTSYSVSSPQTPLNNPNSPNPNQSSYSANARDAALEKSEASGFSNLGGLLNTSDKNKKRTPSRAQKLIGDIFLLAGRSDVAVNIYQAAIETMKINADYLWQAAALESHCVASLIVTIEKAGLGPQPPDESTPSKQKFETEDSVKVNSILDTNNNSFSKILGASNENSTLRNSLSEVPERFREIIILYEKAFQPGHQGFYPITQIAACLKIAKFLACLHLGNFHSFFSGGANFPLNVAETKMITDIAQAMGGSVRSAVGNSIPQTGPSGQNPLDKDRIVLYGGLGVMKVDVNSWIMKAWSSGIEYLSMSDQIWAVSTMAALFGLIGYKRKHSFFLRQTGLVVLSSMKSNANIRRLSGIQSYQHANDSNSSHSGVGSQLLSDSFNSSYQKPTSGTLECMRHVCSALGIGGKDDAFVNVKQVDEDDWLTEYFDDLDLDGHRGVDTVVERYKKRIALSRVRFGWPELQINVLKEVIDIAEASDDYSNAIIYITRLLRRLHKHLSKQEQIELSEKLQGIVIKNRIQSEEPNLMAMEQNCAELSSILVKNVIGGVIGVPVLRRLDIIRQTLRKLPIKHSITELSSSKESAVLKSKDPFIYNPYDKKNGKKNFSKKEYTEVILVVNEPVYFDVTVANPFSFSLDIQSIVIRTSGIAFKSNSTSTIVEGGSRNQIVKVSGVPLESGVLRIHGCTVRMFGGSVEENIDPVSKFLDDPTKSSKDGKKRKQNDRERVGKILSFQKKKGEATQLSNDEKILDTETGWSIDVKVIEVQPVLRADLGFPVNAGALMLFEGEKMEFPIILENISSVKINYLAISIKENYSKVAETVIETAEDAFERDVYDYSLRTFWLKGKSEGEYIGKAINQTIIFELFPGETTEIVVCVYGKRYRLVKSTGGVIKVEYGYIPEMDKSELEDFSSTEKTPKTFFTRQLFIPVLISVQEALIVSNKDILLFGKDSMFLFDNNFSQVNEEKENKIFYNNRSYEISKENQDLKVSFPVKLNPLLKLGNNFLSLEEMMVDPFGDEQGEIMKNLPSSAAKDYCLLTFDIRNVWSHPFEVQFEIYEDESNNIKYSFSTVVHSNSVKRVILPIKRLWLPKEVVEAAIPIPDWKQFVVGKTQKFSDVEEKKRRSLFWYKEYLIGGLNKRGRIVSKWTYSKERTGLFNLRSIHLSSGMLNSLVIEEISFSTNVNNITRNGVETSQTIIDMGGSTYQCQTGDMVELEWTVTNKREFPLNVCFRIQPVQDMQNGEVVMKSLEEKILCLGSLQILSSMKAKSDVKIKLPCLLLKSGIFKFFYHCENFKQENLVTENIFWGGEPIVLNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2H1</accession>
    <name>A0AAD5U2H1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000273">
        <property type="protein sequence ID" value="KAJ3220791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2H1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="452" mass="51161" checksum="C0734AA9927ECD5F" modified="2024-05-29" version="1">MAKAKSNMIANGFTLNNANVNQMQNKLSQQPDNSKQQKSKQPSQKLSEDNKQKSPPKSSVELSNLRLENKLQLGEIQLLKEKISKENHLFQNSKNALNNAVEKAKDLKQKDKKIAVRTLSNKNQTRNPEEYNFFNPSIFALESNAGYRNASPVKFTEVKNAAKLKLQRQQSAVKYTKRYINNFQGLNRPQYTKIDDLPRYETLFLSESKPTEFPSLEDFKSQDVSLIAKGLIILCGALYTMSFLKNFYTGDFSDVNVELPASIFTLLSLSYFALSYFKLEDFSEITARDISLIGRGFLALGSALISYSLYESRDHPQFNEQSKILLLNLLVFYLTVFVVFTAFDSFTSKDFKKSDLNFMSKITVIFAGSFYSLSCLKTYQLGNISAEEGKEIVSVISALALVYITLSYKSTFARFDFANSDFKLIFKAAIIGGACCYGLSFLGDFWNILLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2I0</accession>
    <name>A0AAD5U2I0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="6">dUTPase</shortName>
            <ecNumber evidence="6">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004821</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dUTP + H2O = dUMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000352">
        <property type="protein sequence ID" value="KAJ3219108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2I0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241:SF0">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="dUTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase-like" evidence="7">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3219108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="28098" checksum="ADFA2AD1D55469FD" modified="2024-05-29" version="1">MNNEIMIKRLYRNEELKVYLDNNAKLPTKGSKFSAGYDIYCSSNDDIIIKAQNKNLIPTGIKIELPENTYGRIAPRSGLAFKFSLNVGAEPVFLTQVDKVSETIRGEQGFGSTGKSSFGVYDRYLSTNFFKCSFIIKTIPNESDDISKQECELFGEILLAAINNYNHIKRSQHMFGMIIQDMNVRFYSYVFGINYLSSFANNNRQTYKAIIKRYPSIVKDTLSLLSSDNRKEIIEILDTIKILIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2I1</accession>
    <name>A0AAD5U2I1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003994</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000271">
        <property type="protein sequence ID" value="KAJ3220817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2I1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="NTF2" evidence="3">
        <location>
            <begin position="29"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="346"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="49333" checksum="80BB95C48C94A3EC" modified="2024-05-29" version="1">MNTLERFDSGKDLIDLNCKKFFDIERNDLQYKVLEKYYDTLSNDPKTVVWFYYPSCPAKSLFLKQDNKDQKEQLAKCEEIQERINKYFSTHHYSKNSNQNIINSNMNKIKENYKFEITNLIGTNLVSSTWILVCRGKILKNYRFFKYFEQKFEIKSQFGGFFIKNDFFTFLDYEHQGKEDFEKKSNIIYASKNNNSKNLDIHNNENILQNNNLKKEDNKINFLNADERNLECVEDRSSSTIFSASENLNITSVKNKNNFEQLSSESLQEESKKKIDLVGVAENFASFSTYKISDENTTVDNENIYYTSGNYNNTLINNKFPQQQRFQRSPLTLNSGSNVLEILDENTIFLKNIPNGTTLQDLQSVFKKIGLIKDIRIKEEKKIAFVEFIDKNSVSNCKGKRVYSENGIVYFPEECRRKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Y5</accession>
    <name>A0AAD5U2Y5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002322</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000176">
        <property type="protein sequence ID" value="KAJ3222419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Y5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF1">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="367"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="578" mass="65445" checksum="472FE8C3437A2D75" modified="2024-05-29" version="1">MNNNQYSNKSKTTLSAPTSPTMKLRKSQSFNGIIEESFPEIANTFTSDAQLNASFVKSQSHQELQLENLLKIEPNSKIDSQKPINSERLSKIKFNFRGSKENSVKPSQRSSTTSTISKMTKKESFNWNADDPSDDPLQVHIKPHEKKGKDGYAAMGDTLGHDLNEAISHHLDYSRTLKNYLTKIHQERIETLRTELLVLEVLNKAAKKKRKLLSAKKMANSKKKANNFVVQDQKKFWSRSSVSDVAEKERKNDFCSLDSVKTTASHSVPNVSTVINVTQVSDDSFSEHEEDGKSNRSSLMDKKISSSGKAMDLVSLFGAVIGAESIGGASQGILLRNKSDAKKIARKIFESLTQKDSLIKKDFEPYFESDELNNVFKIFDKDDNGNISKQEFKSKILEIFYNHENIEKSMRQSTQAISKLDSILKIFVWIIIFFVTIAIFSINVSAFMATFLSIWAGVLFAISGSVQVLVQNLIFLFIIHPFDVGDRVEIEKECYVVKEFGLTATCLRLGNGKEIYAPNFMLAQKLIHNFRRSGPQSEPINLSVSKETSFQKIEMLKDKIVKYLELEESREFNIKFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Y8</accession>
    <name>A0AAD5U2Y8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000374">
        <property type="protein sequence ID" value="KAJ3218565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Y8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="640" mass="72185" checksum="D8B129EEED634B21" modified="2024-05-29" version="1">MLSFGKEKNKNVNHVNLQNILKQINNLKQIATSYSQTFINLATAFDAYESNLLSEGSKNTMILSNFGKIFTQIASQIDSMSEMMQNVLVLPSRKILESRAQKLHENEIYFIKNEKELKEKINKLEKDSQKKIPPGSPTFMLNNSTLQQLKKLLENLNISYQNEIFYKEFEVYQFFCKGSNDISNFLQKNLNTQLNFIKDIQNSYNAMQSRDLEILDFEKKLLNSNTKNLKSDLVGTKHYDSLAAPKKFWSLEGKSAKIFTENFLKKNEISQKYEISESSNEIKNRKLQNKSKVMYASVNDKFYTSSSSRTDSSVFNQQKRGSLPSQNDLTSMRKHIDLNGNFFIKENSSGSASCESTMNKENSSRKHFSVNATSLDCIMPLNEIAENLDTAKLLQKKNSQTPANINQESSASIPTSSDKPLVPKCTLQSSFPNIAFFGTEDIKSIPVKNMESTLHISEIVPDNETKSNVATLQGIIEYAIVKWDYEARSGKELNIKKVGALAMLIAVMFAGDSEPTGSDDLKRDDMTTQATLTAIDLSTPTSTLVSDDCKSCVKNCFNNDQQNMEYINREEFRCLANNCGETCLLSRNLPFPCKRCRLLCFMTSPSHDDYDNCVFDNCADCDNGFGSTTTTTTSTTTSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Z7</accession>
    <name>A0AAD5U2Z7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000262">
        <property type="protein sequence ID" value="KAJ3220932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Z7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="267" mass="30523" checksum="6CF2B21B5142BA22" modified="2024-05-29" version="1">MSETPRVIRRDFGGKSSSEWTNDDIENLNIKTEHIKSFNDFFNMSPPVSFSNPDINKLLEINILDIVSEPNSFIRDKNMSWKIKTFIKDLVAVTRVHRNEESAVDDMAKTLLALFEYDDNGLTIRSRPIIKLNMAGTLTQANPDICIEETDTCIKLLVQEDKSANTTYNNSIRSRQAEPQLIAEAIAAYQSNCEIRKTLGEEDKIEECQEVPGITLIEDGYIPAEKTIVRKYIIPGMPIDRENIMLSSRHIKIIAQCYEAFKRFIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3C0</accession>
    <name>A0AAD5U3C0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mediator of RNA polymerase II transcription subunit 18</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Mediator complex subunit 18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MED18</name>
        <name evidence="5" type="ORF">HK099_004354</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000302">
        <property type="protein sequence ID" value="KAJ3220448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3C0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019095">
        <property type="entry name" value="Mediator_Med18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045913">
        <property type="entry name" value="TBC20/Gyp8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913:SF7">
        <property type="entry name" value="RE60063P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 20/GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09637">
        <property type="entry name" value="Med18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="534"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="4">
        <location>
            <begin position="213"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="559" mass="66815" checksum="C799E4D8DA786D2E" modified="2024-05-29" version="1">MSNLLYTLSLYGIIHDEANNLLLERIMGITNNLLLNKNKINYNKHNIIFIPERNKVSEFLQKETSDPTKDGTKKKKLADDIILTLTSNYFNENDNKFIKFNYRNWFLHHLSPPEPQKSNSLPNFRVVNTTPVFGNIFKFLESLGYIFNFEYAEKGYLFEYNNIQIKITKIYTLTKQYKVSTAKLFEKLNDRWLVQLVSNPISQEASAKTSQDLLELSSYFKGWPLLLKRKKEELSIDTEKLTNKLNDNETYELKRQIQLDVDRSLSNFNFHDSSKDLVTMRSNLFDVIFDVFVKNPHLHYYQVLNEKNSKKVLSIFSNYYLRDLMEKNMDGTIKQMEFIYFLLSKLDPELYHFLNSIEGGSSPFFSLSWILTWFVHDNDFILMPRLFDFFLTHNPVIILYFSTILILDNKMALLNLQKDFSLIHQYLTNIKISKTSFTPEQNSIYLNKLIYTTLFYYQNHKVYSSINNLKYFFGINSCLTRYENDFQNKPELEDLDFQKVIESQMEWREFNKKRLEEVHTKKELKDYMLRYKKFFIFSTSLLVLSLSFSVYYYKELFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3C7</accession>
    <name>A0AAD5U3C7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fanconi-associated nuclease</fullName>
            <ecNumber evidence="5">3.1.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002016</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.</text>
            <dbReference type="EC" id="3.1.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.1" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000163">
        <property type="protein sequence ID" value="KAJ3222706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3C7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070336">
        <property type="term" value="F:flap-structured DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004528">
        <property type="term" value="F:phosphodiesterase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22326">
        <property type="entry name" value="FAN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033315">
        <property type="entry name" value="Fan1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049132">
        <property type="entry name" value="FAN1-like_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014883">
        <property type="entry name" value="VRR_NUC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15749">
        <property type="entry name" value="FANCONI-ASSOCIATED NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15749:SF4">
        <property type="entry name" value="FANCONI-ASSOCIATED NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08774">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00990">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VRR-NUC" evidence="6">
        <location>
            <begin position="598"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="728" mass="85874" checksum="C73442AC0093ABCF" modified="2024-05-29" version="1" fragment="single">MVNQVLIEDYHLFHPSEITLLKKFLTFDQQEKAIYFKLLNRKIKPILLKSFKIPSDRDVVMKFDTNFIIVNPNLTDLNILLSLLVKEELKNFLQKRNLSTLGKVKDLRTSLIKNIRDQPFFSFYATREQNSEEREKYFIRKFLTPVLGTIIQIDTTTRELFQKVILLYNRDTILEKNLLLNSILTNIKVKDPKLQLEEDEEEETDSVNTSVDPKKLRIPRIYPNYKINRLSPFKYKTRDDFLEYFYCLNLEAELIDKVEFGDENSLNEGLRIYETAKKLWMTHIQGLTAKVDISSCKNEVKKEVIGTEIVGTIPWFKLYTKEFVLSRIMDFSRKLLEKLAMLEIKKKPLNGEIVKKKFLDRIDHLNTLISQPFYYQHKIYSWYNELALIYHYHLKSPQEALKLCEEALSLTNENLRNYACGRRNAIKKRMKRIREGKNCKKEDIELNANVLKVLVFAEKAERNIKEKGGNYGKAYYYYPLDITEKKENGETGNDAEAEKLYVEEFVLKKYFEKGWKGFHCETRIFTTLFSFLFYDILFYDIPGVFISPYQSNLDETFINLNFSLAHPLDFGTEFFYESRKNLIEERISVLERKSEEDNWRKIQELVCEVDSLCRDKNTFVYGISWELFSVDDILKIIEYIPGNALSGIVKFILQNPMGGGGPDLCLYNEHAKKVKFSEVKGQNDRLSETQIIWLNYLSELEGIESELFEVNVEKKRKAKTPVNRKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3D6</accession>
    <name>A0AAD5U3D6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001966</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000161">
        <property type="protein sequence ID" value="KAJ3222751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3D6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055308">
        <property type="entry name" value="TEX47-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34035">
        <property type="entry name" value="TESTIS-EXPRESSED PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34035:SF1">
        <property type="entry name" value="TESTIS-EXPRESSED PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24787">
        <property type="entry name" value="TEX47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="249" mass="28739" checksum="DF9F76C125BB9F61" modified="2024-05-29" version="1">MEENDKISDDQKRISLLDVVRDNLQRQEKTQIIYRVIVCGEIVRNQLVNQTTQNFQNDVGVHHQKFFKQFQVENEMITGLLILHTSSWIHILEASQPVAISYLKELDSNNSKALVKSIKVLLLQEDIRERCYPYWASRSIDFNLGEGDKEFDDNRLQGDELVKTVTDLSVTMLKLGTNLSNLAKDLIKPALDDLAEKYRHMIPFPELITALSNCDSIINLKDWLETFQGHISWVSESEIVWPAQKLLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3K5</accession>
    <name>A0AAD5U3K5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_003401</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000223">
        <property type="protein sequence ID" value="KAJ3221556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3K5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000060">
        <property type="entry name" value="Sensor protein FixL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052162">
        <property type="entry name" value="Sensor_kinase/Photoreceptor"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304:SF1">
        <property type="entry name" value="PAC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304">
        <property type="entry name" value="PHYTOCHROME-LIKE PROTEIN CPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="563"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="759"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="805"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="879"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="382"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="276"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1038" mass="119029" checksum="43989E3EDFE34001" modified="2024-05-29" version="1">MSCPFIPAENSALISESVTTTSNPLENLIQATTVASAKDLVNDTVEVYQDENERKLAEYVAKVDGNRKTTGGSGFKRTQQSKIDSLIGQLLGESLKIEDEIFVGENELFHKNEEAFFILQDERELANLKARQSEEIKALKTMQETGTADMTKRKATKKFLRQQSRETKALYNRTHEQEAACKQTQDEKQTLCDDREKSARLVEHMEERHLKQIKQFNAAEERKISDQRILVELKIRHLTEEHRADAMKEFHSKMNYQKDLDKKKLDQICEFQRIELRHFKDKVDLETQMIEELQNLHSKHEVEEKELAAKQKIDYLLEKERIATTELSLKVIIIQAKNLIELKKLQNVHRLQLRQLRKAQKGRKTKRLKHWSIILGRDLTQKKRRTGSALQSSGGSNDGSEDGSESGSVGTHSKPESLSHTRQGSDSNIKHAAGAKKNSDSPRINLIEAEEDDDDSHEKNVSLDTQQQNAEEQLNKMREQLSALREQQFEKLRKLKKKASNEKKEKEEEFQRFIMELEWQQDVDIKDLKKNDETELQEAIQAQERELEMEAHIRGAETKAMLERKVLKSLLDSVVDGVVSIDPRGFIQRFNASAEKMFGYTDGAAINKNIKELMPPEYRENHDDHLYNYLKTGVKKAIGRGVQVKGQRQDGTIFPIHVSVSEVMEDGFHLFTAIIRDLTVETQNAIAKQAEDDCLPQLIWKIDIKGVAMSFNKKFINYTGVQSDHLSTVNFFSPDIIHLEDLKSSKETFLKSNKGKMPFELKMRIKSAEGNYKWFLTRGTPMFDVEGNIQFWCGSCTDINASEILQMELSVLPNSITAILWHVNNEGELLYANPRYKEVTGIDYSTLKIDIFSSEVVHKDDVAKSISSFTEALKHKTSFEVTSRFKSENGNYRWYLIKGTPSFSSAGDVDGFYGTSSDVHGSHSIQDELLIFPENLPQLIWKCDCKGNTLYTNSKFRNFVGIDEGQKFNVFTEALLHPDDLKPSKESFAKANKEKVEFEFKTRLQSENGEYKKFRTLAVPVINDKGDVTAWYASSTQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3R2</accession>
    <name>A0AAD5U3R2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000432">
        <property type="protein sequence ID" value="KAJ3217339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3R2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="28"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="229" mass="25967" checksum="AAD1E67CDEE2A737" modified="2024-05-29" version="1">MTYIPAKLVYMNSKKNKKKTFFLTEVENSIGREKGNSLHLKHCLKVSKFHAVIENIQNSYYIRDTNSSNGIYLNGKTLETPFLNYLLFNGDKILVGSIDRTAVPDNKTFRSIVHILYKEGFLNSYQLGNEKGPYNQPTKTTPLNVARNRLWLNLKYRDGEPALRKFKCVSLPSRAVYASYEELKAVAAARNGSKLFKAQVLGQITILQTVNHGIIELHEAIEKKIGGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3S0</accession>
    <name>A0AAD5U3S0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000127">
        <property type="protein sequence ID" value="KAJ3223501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3S0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="75"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="498" mass="57915" checksum="17D0D6FBE2108438" modified="2024-05-29" version="1">MENELFEFTVKVALTLESQNSKDEELMELHDKAVYLIEKMSEKNKPTDYSISQFSPKILDNHYSKSKNKSHFTKRIPDEILLSIFMHFKTDESESNTFLVNLSLVNKQWSTVALPLLWTQVYSNHDNLSKLHLLNVGLKLNQEYRKKKSGWFNPNIVLLEFFSDMKFRSTLNKKLFKNLLGVLLLYTKNLKSLSFCIMSGSDRINFNLDDLHNIFTNCKLLTKLEINLLEFSWNKDYDLDELEKKNISIKSGFSKLKIFSLLELKGKKEDFFKLYPLKSVEKLEIDEISFSLAKILKGNLKNLTSLSLTGSLDPNDPGDFDFNAADLIFSEAKNIKILDIQLKYNDGIFLAIIKNNIQLQFISGKIDGRQRSLDFVNWETLSKFLKFSSESLNEFHFTLLLDETERYHSHDTELDDSKLTFISNNLPNLKSFGFYIRNENFQPISAWKKVSVESLKKFLSKPKNKIVRIGVNQEILFGTRVDIQKIFDQSGIDYSESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U557</accession>
    <name>A0AAD5U557_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">L-lactate dehydrogenase</fullName>
            <ecNumber evidence="3 9">1.1.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_003291</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-lactate + NAD(+) = pyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23444"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LDH/MDH superfamily. LDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.27" evidence="3 9"/>
    <dbReference type="EMBL" id="JADGJW010000218">
        <property type="protein sequence ID" value="KAJ3221635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U557"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004459">
        <property type="term" value="F:L-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006089">
        <property type="term" value="P:lactate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00300">
        <property type="entry name" value="LDH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011304">
        <property type="entry name" value="L-lactate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018177">
        <property type="entry name" value="L-lactate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01771">
        <property type="entry name" value="L-LDH-NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128">
        <property type="entry name" value="L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+))"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128:SF16">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00064">
        <property type="entry name" value="L_LDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="10">
        <location>
            <begin position="4"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="143"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="116"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="305" mass="33006" checksum="1E6DC23EDEB7DC2C" modified="2024-05-29" version="1">MSVISIIGAGSVGSTIAYTLVTSKVCSKLLLVDVVTERAQAEVGMIDYNETNDFDTVVEAGSFKKAGQSDIIVITAGAKQKEGETRLDLVGRNTGILNGVFNDMAPLNPKAVVIIVANPCDILTYIAQEISGLPRKQVFGSGTFLDTQRLRAYLSSTLNITESSIHAYVMGEHGDSQFTAWSAGTIGNCHIDSILPKDFNKQQCEDYVKNKAYKIIKNKGATYYGISACVKSLCSSVLFDSRHVCMISHYIPHLNVCVSLPCVLGKNGVELTLTPHLNEKENASLLGSASAMRNTLDSYRTKHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5F9</accession>
    <name>A0AAD5U5F9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor A domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">VWA8</name>
        <name evidence="3" type="ORF">HK099_001063</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000128">
        <property type="protein sequence ID" value="KAJ3223480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000587">
        <property type="entry name" value="von Willebrand factor A domain containing 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039891">
        <property type="entry name" value="VWA8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21610">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21610:SF9">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase dynein-related AAA" evidence="2">
        <location>
            <begin position="65"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase dynein-related AAA" evidence="2">
        <location>
            <begin position="416"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1440"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1440"/>
            <end position="1478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1582" mass="179688" checksum="E4F124CFE5A1059F" modified="2024-05-29" version="1">MSTLRRLDQLNNILSFSSESEEKTLISIGDIKKYLKVASAPELIPYLNNELFFAESQEVLSLHQDVFLIGPPTNFKRRLVLKYAQLTNREVEYLTITKDTTDADLKQRREIVNNTSIYTDSVCVRAALMGRILVLDGLEKAERNVLPILNNLLENREMSLEDGRFLCSPFRYENLVSKKTIGLRESKLCKVSENFFVIALGCPVPKYEGYHLDPPLRSRFQARNIPEPSFDTQIQFLKQLSPSIPLRLVERVLSIKFLFNSKDSFSSNESVVDDGAVKIPEFNGNLEVLLKLLEKFPNLNVRVLLESCYPFAELNDVLEQEQIDLIEAGYSRFDFIKCEKLKNSIGYGFNYMERYKNTENNLNLASISFKDLIKLNIVKLVVNAGSHPSQKFQNFVTTEFHQKILNTMFFLHSVTDFCLIGPPGVGKSAIVRLFSRKLGYNVETIPMYRDLSSRDLLQRRGTSGVGDTSWEYSPLVKAAIEGSIAVLDGIEVLSFGTISILKTLILERFCFLPDGSLLLSSDRYNDLNESENFETMDTTSFSRPKKILPIHPNFRIIALARPLSSVTVKKGLWLSPEVNSMFSFIYVRPLSFKEENQVLREFTKVPEDNRYVELLLKFALFIRSSNSSESKDIARELSTRQLTRICKRLQSFGGYSDLHSEILKACLFQFLPLQTKNFLKKSLDENLIFCKKIINENKGLKIEILHVSEKESYLKIGNVQLRIRNNTNPLLVPEVIFHENERQTIVLMEMLKDFSLGEHLAPTHVTSILKSLVEDGEMVLSDGRRIVTKEIDAFGDPKDYIFMHPDFRMFVLANRPGFPFLGNDFYAEIGDVFACHCIDNPDPDSEMALLLKYAPTVDKELLQKLLNSFNDLRRLVDEGLINYPYSTRELVSIVKHIETFPNEGLSRSIQNVFDFDQYDLDTKKLLFEVLTKNGIPVGGEKDFVVNVGMEVFLDSPKLLETWSSLRGHKILVHDIKTFDLHIKEGWKLVFSKVFNLDIVLGRVKSYTELLYSFKIPTNILKNGEAADSIILSNGEVLILTINPVTLYRIDASFRHATPIDLYEYFPMQKISFKFKLVELEPLKIFICNEKDNKIVIIDLKSNVSKICFIENITSNSLIRVCDSLKSYGILVFYQQGLNSIYVLDLKNQFQHIINLSIKINALHTVTKNNWIIQQYDNTFDTFKNFTLSSPDNIGIPNVLEEIKINSSVSSNAFELGSICSFPSDKFGYKNSQRFIDLPSFECYSALLCGFPGKLSESHLENIEIRAWPRSKGEEIRNSYLNIENSFLHLTKSQLYVTATPGIDGRNMGFLEFFDINKNSLRKIKVPLAMPAKATLKKDANLTNATQFQKKKNEKKLILKLIELDDGNLLTIDLKGTCRVWQVEYEKILTDLITWKKLTGGIDNESLSIIYNNGIVFDNDLNSTEKNVAVYVSELDKNGIGEGSGSGSGKGSGEGSGSGESEGGNEGAAGGSGGTGGPGSAEPSLEGRKSGTIDVSNFKFRLPGEIPKEITEARRDLHDLAMKKRLQQLGMTGRDMETFQKYHQNVKREITELRRILETVEAKNKERVWLRNQSTGDLDDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5H1</accession>
    <name>A0AAD5U5H1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dpy-30-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007437</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dpy-30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000072">
        <property type="protein sequence ID" value="KAJ3225062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5H1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22965">
        <property type="entry name" value="DD_DPY30_SDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049629">
        <property type="entry name" value="DPY30_SDC1_DD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12360" checksum="08AF5A81A0815695" modified="2024-05-29" version="1">MANTEVEEKKEEKEISESEINTTPAPPAIQINKELLEITKLLNDAVNSSSLMTDKSQLLALPVRSYLDATVVPVLVEGLKSLVKERPPNACEYLALYLLRESKCDGFQNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Y6</accession>
    <name>A0AAD5U5Y6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OBG-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Y6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01899">
        <property type="entry name" value="Ygr210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.470:FF:000001">
        <property type="entry name" value="GTP-binding protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="YGR210-like_G4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF1">
        <property type="entry name" value="OBG-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="YGR210-like_G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="6"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="514" mass="58312" checksum="E06F48498E51B444" modified="2024-05-29" version="1">MGIPEITIGCVGKPSAGKSSFLNSATDASAKVGNFPFTTIKPNVGVSYFKIDCPCKRFNKAQFCNPKRGKCEDGNRFVPVKVLDVAGLVPGASEGKGLGNQFLDDLTGADCFIHVVDVSGTTDANGKVTIGYDPSNDVEWLKFEIHNWIYNNLKRKWPEIVRRHVAKKSTISQTFQLQLSGYGTKIQLINKLVENFDNRLPLESWDDDTLRAFVDVFIKFRFPTVIALNKIDLPDADKNIDKLAKKYDPNQIVLVSALAESFLRKLQKQKFILYEEGTEFFKTFEDLEEDRINDPTIINNLKLMDEKTRARLEKVQDLVLFRFGHTGVQDTIKKAIELLGLIPVFPVRNINNFTDDRYVFDLFIIANFYLITSGSRTSIFGDCFLIKPGTTVLEFAKMLNPEIEKTYQYAETVGGIRTMMRALGFHYSVEDLDILLQKISKSNGTATEQTDYFTLDRVISVCTFLYGGRDSREELSRSFNLFSSNGERVTIKDLRRIARECGESMTEVYKKFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6G3</accession>
    <name>A0AAD5U6G3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000212">
        <property type="protein sequence ID" value="KAJ3221732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6G3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="546" mass="62123" checksum="A85DCC4C343C550D" modified="2024-05-29" version="1">MDMKSTNLLITELKRDLDENIRILSHTETDLRNYIQEYKCYYLQHKKSVDKLNEMIELENLKYQKETLIPPANFLPFKFKNLKLLKLYNQKKATDYKNASDDFEADIAAPNSMLVNTSNLNLNESNSSINTPVDSRTSTFDCTFDYDYSDNVVVDYFNDDHSNPLQKGFNAEKVDEIHYNNDSTSKDLSDVAYEKLEINESNNSLNDLDIVTEEQSYSIIESDEIIDSLSDSSGKESLLISDSEKCESVIEVVESEHVFSLSVAEENSQLIYKFFQNSDDLKSLNGITNESVELEVVAALSTTAEEESTTDLQSIKKICEYLDDTNNISETSFEKEHSGNSNNLSDETFNEVYNDIDQDIKLTLHCSDEIEGKVPDHFVAKEPVELPILKVKKNKKKNSKKKVEKYQEIEEISKIEEIEPTKHYTSKDELALKSTEQTTTKNRTKSQLRKLRRKKSSLNMDLGDFSKGDLGETLIETQNIKVEIVVASVEPLINSEEAELKDAQNIGSIAEITKNAELKEPQSIGTIVGITKTKGKKKKKKSQKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6H9</accession>
    <name>A0AAD5U6H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sperm-associated antigen 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SPAG16</name>
        <name evidence="6" type="ORF">HK099_007900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6H9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF3">
        <property type="entry name" value="SPERM-ASSOCIATED ANTIGEN 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="330"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="372"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="414"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="456"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="498"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="282"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="617" mass="70691" checksum="B98736314D84732A" modified="2024-05-29" version="1">MLKPLPQLPKKLNDSSNNLEQENKKASYYIQEHSFNDDDVEESEEFLEYDTIPLNEFEDLEDIDEDEDLEKAIRNNNEQTFFGAEVTKNDDPVVEIAQKPEVIDDFIRNFLCSKGLVKSLDAFQNEWYEMQHKGKLSPEDVSLVPDVYQRNQDLAEVLKKSRIEVENYKKIANNARATYDKLRKERDFHRMHHKRVVQEKNKLIQDIRRLKTHYENYEPTLKILQHKYEISMKEKMLTKLERDRLASKIVGLENSGATKQSNVAASVKSSKQQKTKKNILEKNNTQLQQPFQQKESSFPVEDRQNPYRSPGYQESIQPTKIEKLKLIQTIKAHELTISAINFHPKKMILATVSDDKTWKMFAFPSGELIMSGEGHKDWISNCDFHPRGTHLATSSGDHTVKIWDFTKGLASLTLSDHTQPVWSCGFHDTGDFLISGSMDHTAKLWDLQTGKCRQTLRGHADSVNQVGFQPYTNTIFTGSSDKTISFWDSRTGLVNQTFYGHLNSINDVVFNNFGEKFATCDADGVVKFWDIRKSSVELESINFGPYPVNKINFDPSGNILGVAGNDGLVKLYNTVEKSKSKNLDYNNGNSLQGLIFDKTGEFLVICSSDCTFKIFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6N3</accession>
    <name>A0AAD5U6N3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000040">
        <property type="protein sequence ID" value="KAJ3226271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6N3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF8">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="38"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="590" mass="66936" checksum="F33FC0D49F6F1164" modified="2024-05-29" version="1">MTVSIITENTKILRSAYSTSQIHPSLTLIPVGQQMSSLFTTTAVLQLVQSKRLKMEDLVSDFFKFNCSDSRHTVFKMPPFCQSEVTILHLLTHTAGLEHRSFQPGEHTFGEQFPRIVHPPGKIYSYSPHGLALLGKIVSMVTGMPFDKYVEEKIFLPLGMLNTGFIAPNSDSKLLKKFNQSTTSTSSAKPHQHLFTPHSIKSDTFSKSETFEATKFDINDNFGWFSTVSDMNLFMEASLNKGAAGNSDSHLYGSVPKRILEEPFADLMQTPHKSHTKSLSICLGYYETVIKNTPILFKTSEATGSSHIMAILPDEYIGFYAATNSNNPKYLWEVLEEFILTYVDGRAEEKKRTIDATDELKFDLEDSEFLGTYRLTSTSYTNYESFFSLFSQAQVYKSGESLGIDLPFSGSFYIKKTTGNGSFLMDDGTQLTFKRYAGQVRYVFTEDSEHNPVTFERVDYDSASVFLISAVSIFVIIYEIFQGDRDMDASFLKFLIFFNCVSQSLFIALGLPLMWLTHGERFFNLLPILKKVFILPVISQFLTLAGSIALLFFGRLEKKSVWHFLVLICCFRLCLYEIQFDLTFFDLPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U758</accession>
    <name>A0AAD5U758_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000068">
        <property type="protein sequence ID" value="KAJ3225198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U758"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="307"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="413"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="493"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="600"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="960" mass="111297" checksum="C70FCB619BA27008" modified="2024-05-29" version="1">MNDRNFNFSSTMPDEEDNVHESNHSETAKDKIMLNNQTMFANNGTELKSKVLTFNEYSKNSVAETKSQVFNQRQNAGNKLESQQMLHSKNLNLGNNDFLLKTRNDILSDNGVNIHNNLKKNNSPSSFSKNDFKLPSNVTLNFDVNNRKSNYQNHSVKSHDENTPNIASSQHYNKKSTQLNASQIPQEIAAINNNFYNNETFQSTSESEMSDNFNSPLYSSLTATPYPSPVGLSEDKQMEELIQNMLVKQKKVKAVQDLKLKEMSSELSEARSLVVAQEQTIQTLQVNSKIIMGSVAERQKKTETIRKRYTKMAIKKLEKMVKETENEKGFLLQRIEKCVEDNFNRNNHKKEVAQLNEKYNDLNSQFENLKKEKDLNEISISDWKNRYNQQVEIFSKHLNDYREDFDEFKNKTKQEYLEKEVHLNKEIESLRLKWEKSEENLKYWNSVKLTMEETVKTLNAKIEHYESNEKFYKDSIKQLGLSVSKGLSNNLSVEEIDVSINNLLLSYEELQKKVLTVENLVKTTEEIQSAKIVELNNTFEKEKKLLIAKNTDSINDYRNKELIQQKKLECILAENKKLQSTHEENLNILEEMKSSAMESQNKYESRIEFLKESIKSLEARITLETEILEKKDIEFVKKNEEIEELKDLTNSKIRELQIEFESKEKAVFDLSKLKDAQKFEFDNLLNEKNFEISKLQKLNDEKDSELNQMRTALSLGVYGSENISPVKVKDYEKFNIKKDLDLVLLKENEVLSQKNEQDTSIIVEKLKLEIENLKSTFFHTEKSLKDEVTGSFVSALPSNNNESNISFAESTRFSDFDLLQNATEEIDLNDPSNIPFSLAPQFRYDTEEFPTANTVSLSIENSTFKKKINSQSKKRDFIEINDGQSEDLNEAVGSETFCTQDKFSKKKKSTKKKSTVYSARVNQADLVKFEEDSIDDVTPDTQFQTLGRNIKKKVRIMNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7D9</accession>
    <name>A0AAD5U7D9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000942</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7D9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00812">
        <property type="entry name" value="LeuRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000002">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000003">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="14"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Leucyl-tRNA synthetase editing" evidence="11">
        <location>
            <begin position="210"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="10">
        <location>
            <begin position="552"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3223592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="841" mass="97388" checksum="CCC9434FEEEB02AD" modified="2024-05-29" version="1">MKRLKRAFSTCRKILAINNNSSNFYVLPMFPYPSGNLHLGHLRVYTISDVIARFNKLCGKKVLHPIGWDSFGLPAENASIENKVQPSVWTALNIKKMKTQLKDMDLDFDWDKEIATSDPSYYMWSQKLFLDLHSAGLVYRKKSQVNWDPVDQTVLANEQVDSNGRADRSGALVEKKELEQWFFKITAYADELLDDLNELDWPNKIKVLQRNWIGRSEGIEFEFQVLDQQEKIKVFVNKPELIFNLKYVILSYDHWIFEKSFVPLGLKRKIKNVATRNSVFNTKTDLHIVNPFTRKPIPIYISFNSEFNYLNSHAGFPEFIDADYQFIKQFKEFNKLKQLKLLISNLELTEKNHSFANFDDVKNYVEIETEKNKIGIKKNQVVPVPEQDLPVILPTNLILNGRGQSPLIDAQDWVKVTCPKCDKPSRRETDTMDTFVDSSWYYLRYCDPNNNLQYCDEKLNLLPVNIYVGGIEHSILHLLYARFVGKFLSKQGICKLEKGEPFKKVLAQGMVKAETFKCPDTGRYLKKEELFFFDPDNPIVMATKKPPKKSWEKMSKSKYNGVEPSEVIQKYGSDATRLFILFKAPPQEELSWETQGIVGMTRFLNRVSKAVSAFSSKEFLIDSENDIMLKDALEETVEKVKVQLSSTYTFNVVISDIIKLFNLTQKLNFGKAAYGEALISILKLLSPITPQFSNAQYKLFFLKKFQLQFNKKEIPISENEASYKKISVFDLETSLFSDRKFREISSKEKERVKSVQDYYKGYKIFKAIINGTVRGQFKVEVAKLENLNDEELKLKLIEILKGCEIGENYLKGKQVQKSFLSKKVVKGLRTFSMVTGYDLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7M6</accession>
    <name>A0AAD5U7M6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiopurine S-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000713</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000118">
        <property type="protein sequence ID" value="KAJ3223757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7M6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183:SF11">
        <property type="entry name" value="THIOL METHYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="24465" checksum="03361852763A17AA" modified="2024-05-29" version="1">MSQKCRELKDTPWDKEKLSAPSLMKLLNTKQYPNFSVPEEGYFLVPGCGSGNDVINIFKAGPKRHSIGLDFSSIAIDQALEKVKNSDIDASNNLGKIDFCSGDFFKFNYFDKTFDFVYDYTFFCALEPSLRTEWGKKMAELISDGGLLVTLMFPIMEFSEDGPPYPVSLEANSIHSYQQVLVENFELVLHEKVVESFPGRQGRENLAVWKRKNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7U8</accession>
    <name>A0AAD5U7U8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7U8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="96" mass="10651" checksum="C77AB2FBE1AA92AB" modified="2024-05-29" version="1">MLTENNIKKIISRDSDLISATDHGLNPILKLHKQPYIDYLKSAYSNWLSIGGSEIGVFPDVFPVRGFNNEKRLNAGGLGGEPGYYCFDFNSIIVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U814</accession>
    <name>A0AAD5U814_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000459</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000110">
        <property type="protein sequence ID" value="KAJ3223975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U814"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF28">
        <property type="entry name" value="ISO-OROTATE DECARBOXYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="4">
        <location>
            <begin position="11"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="344" mass="38938" checksum="23F09C96B3DB11DD" modified="2024-05-29" version="1">MTVYNSLGKVVDIHTHVYLPSLMDILRNRLVILPDEEQDESLTKGRPIGSEYWSTPRKLQFMDLHNIQTSVISTANPWLDFLKAEEQIEAATKLNKDLSDICLESDKRIYGFGILPLYSIKASIEEVNRIKGLFGLRGIIMGTHGAGKGLDDPNLIPLFAEIERLDLVIFLHPHYGIGNDKFGPHDFGHTLPLALGFTFETTIAVSRLILTGIFDKLPNLKFLLAHSGGTLPFLAGRLDSCVIHDPQMAGKLLEKPSFYLKKLYFDSVCYGESSLKCLLNFTSVDNVMWGTDNPFFPPLDVQNDVYEKPWLSVVENYDCMMYLDVADREKILWKNANRILNLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U845</accession>
    <name>A0AAD5U845_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_006126</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000051">
        <property type="protein sequence ID" value="KAJ3225828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U845"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3225828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="158" mass="18623" checksum="7D1A51B4EFE1AB6F" modified="2024-05-29" version="1">MVNFVEKLHRLLNEESLKHCISWSNDGLSFVIKNSTVFSKVVLPVTFKHSNFVSFVRQLNLYNFHKENRNYHRHDTITDEERAAEPREYSHKKFIRGRPELLKQIKRKNSPVTKNKENSKSSNSNTETLDCNNQTFNIPTVESNDFHLNKFALNLFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U883</accession>
    <name>A0AAD5U883_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PSMB8</name>
        <name evidence="11" type="ORF">HK099_004286</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U883"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03761">
        <property type="entry name" value="proteasome_beta_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000051">
        <property type="entry name" value="Proteasome subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF3">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 10 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3228293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="287" mass="31619" checksum="46884FB03FF33474" modified="2024-05-29" version="1">MALVNLNDVLSFTGNEEDSAFDDAKSSCMNFETSLNFKLPTFSIQNLSDVSDIATAPVDFLKQQMSNENNSRIAIKKGTTTLAFVFQGGVIIAVDSRATGGAYIADGGVKKVIEINPYLLGTMAGGAADCMYWERELGRRCRLYEFREKERITVSAASKLLCNIVYGYKGMGLSMGTMVTGWDKTGPGLYYVDSDGQRLKSDLFSVGSGSTYAYGVLDSLYDYNMSVEDAIELGTRAIYHAGHRDAYSGNTVNVYHMKKTGWEFIYNKDINELHYKYAAEAKPSTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8A7</accession>
    <name>A0AAD5U8A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM154 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033336">
        <property type="entry name" value="SAXO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516">
        <property type="entry name" value="STABILIZER OF AXONEMAL MICROTUBULES 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516:SF17">
        <property type="entry name" value="STABILIZER OF AXONEMAL MICROTUBULES 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05217">
        <property type="entry name" value="SAXO1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="616"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="628"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="772" mass="88786" checksum="ED77A96EE161C832" modified="2024-05-29" version="1">MTLKSDTLVSSNNPVISEYTEEYIKFRVNKPILEKKKPDQKFGGAFSSSTEHHDQYKVYELKKAAKAGPKNEFVKSQATLDSATTQKTDFKQFSIEPRVTGKPHENNLKSGGSFSNATENNEKYVKHDLPEKYKIPKAEYVPTQGRFSNETTNKEDYVKWDVSNRPSKRTQVYKPKGDKFEDSTTQGSDYKDFGVQKLYRHANQPYIKNDNKFEGISTNNTDYIKFEVQPRVKERGLESCLKTGGTFSKETENHEQYIVHQIPPKFKIPKKGYVPTEGKFSDETTQGTDYKNFGTQPIYRHPHDAYVKNNAKFEGISTNNADYKKFGPQQRVSGKPLQPCLNVPKKPYQSSGAHFDDSTTQGTDYIDFGVQKLYRHPNEPYVKNSAKFEGLSTNNTDYVKFNVQPRVKGRVLENCLKVGGAFSKETEKRYIPTEGKFSDETTQGNDYKSYGRQPIYRHPNEAYVKNLSKFEGISTNNADFKTYAPQPRVSGKPLQPCLNVGGDFYGNTENHDQYKQHEIPKRYQIPKKPYKESGAHFDGSTTQGTDYINFGVQKLYRHPNEVYHKNENKFEGQSTNNTDFVKFQIQPRKIAQGHQNNLNCEGSFSKNTENRDEFVSHQMPPRFKKPNRKYEPNDLKLGDSTENHDKYIRHQLGERFEIKIPKYTPNKAPLESVSTQKSDYKVWPIPEKFVKTVPKGEPAGKFTGTSTNQNDFKAYVVTRLEKRVPKYLVKDLQKLEGESTYDHDFIYKNKAKAALDNEVCLKNFVKVHQPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8B4</accession>
    <name>A0AAD5U8B4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Suppressor of Sensor Kinase (SLN1)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SSK2</name>
        <name evidence="8" type="ORF">HK099_008657</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000098">
        <property type="protein sequence ID" value="KAJ3224266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8B4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000165">
        <property type="term" value="P:MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF32">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="161"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3224266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="519" mass="59328" checksum="821F731E008A41B5" modified="2024-05-29" version="1">MESDKSDGSEELNFKINRTTSTKKSALSSLTYTSPFSGRIRTIDKGAVGYVFDILSSKLNDQQNSLQTVLTTFSKEKKKKIEDLSLNNLLEFAQSFNKNPNFEKQKPNKQVFTLLHELDLNLKRLSKSLHDPSINPHKSQDLFENDTEESMDNFLKLFPEWKVERMLGSGACGVVFAADHPVTKETLFAIKKTNLNLNPAVYYYAVIKVFKLIDHPYIIKYYGCEIIEDHIYLFMEYCNEGSIYDKIYKSPENELLGPGIHDNELRKLYIKQTLEALVYLHGHDVIHRDLKPANLLIKDGVLKLADFGAAKLWYKCCDKEHNDNNMSGSPCYLAPEVITDTQEMGPKGARDIWAVGCLLFEMVLGKEPWYQIDNIWSLYYLMGTWASRTRDFKSETSDDTPIQMLRGCRVCDDFESDDESQFGSENSEVVEDLVEENANKQVNLEETAENLKKDVGCGIFDINCIKTAKNITNPLITIAVNSKRFSADALDFLNLTLQWTPENRPTAFELLNHPYIKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8L3</accession>
    <name>A0AAD5U8L3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flavin-containing monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008202</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8L3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="56369" checksum="64DAADB4451E79CD" modified="2024-05-29" version="1">MKRSIAIIGAGPGGLRVLKDSIENGLEPTLLERGSSVGGQWSPRNKENHHSSTYESLITNVSTEMSCFSDFPLPFNTPDNIKAKDFYKYFEDFVKTFNLENFIRFKSNVIDITPIEVPSKIKIGSKGWSVTWKTENGNLERGIFDFVAIAIGFNSKPNLIHINGEETFTGRIIHSHDFICSSYFEKEKNVVVVGSGSSGCDIANELSNIEDKKVSLSIRNSAFIYPRVINHKPLGQITFKRYLHYRLIKFWNFFFTIKKNIYILKATFPYIFKPTLRDFFNPPKRVAIGTDIIKSISEKKISIFPAIKKINNREVEFTDGSKLSDVDLIVTATGFLRDLPFLSKEIITTPAKTSLGLYNSIYPINTSNLFFIGMVGSRGSIVSLVEFQVRHLMAVLNGIVQLPTDIEMKKEVGIPQIGKSNDLVDTISYYDKLMKPLGATPNFFKLLFSDPYLAYCCWFKPCHILQWRLTGYGKFERAKKDLLEFCDRYNNLHFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAU6</accession>
    <name>A0AAD5UAU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucose receptor Git3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001126</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAU6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023041">
        <property type="entry name" value="Glucose_rcpt_Git3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11710">
        <property type="entry name" value="Git3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose receptor Git3-like N-terminal" evidence="6">
        <location>
            <begin position="6"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="190" mass="21377" checksum="3E4EAC9C08A0AD67" modified="2024-05-29" version="1">MSGSNAQNAVHLVNKYIYLIIGLIWGVSFSTALVGYFFAGYAWTGTWCWFPEQALYPRYFLTHGPRILIFLIIIVTYTSLFIKLKREVTSKGSEKREIKSFESTHETSSQVNKTVNKMLIFPAIYVLLWSGGMVNRLLDATTGATDISRFLQGFTQFIPFADSILYAAVIGLKKIKIGDSTTNEFKSSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB20</accession>
    <name>A0AAD5UB20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB20"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="789"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="819" mass="95558" checksum="6B3D821A34A3E455" modified="2024-05-29" version="1">MSAGTSKSTKTAKTNNTYIFSKDAFKVPPKSQVLVYELELKEIFERYQTTPSRERAAECFRIFNEILPYIGAFSSILTTIKDELYRSVYSQDLTSKSAEPYLERIPYFKSVKRLEKLRNEECAKMQTSESDLQQKLKFKEQDLQISYKKSLFLKEDVYARDVKIAKLTKQIEALEEQQRLNESEKTELKICSFQKEKDLENKVESYKISLAQSNHIIEKLSVFKTSYVENADMIFEDVNKLKRANLEMTPEAMLKYDIIQGEQLELQFCEMLDYQLDDFETSISQLQRKKEVLNLVSSSSSGSSSTTEDRENSHRLEMRDINVGFKKRVSDLLEEQNLLKIHVDMLKSNLEKITSEEDVKVRRNTDEGKKKYAIKTLFCPHRLSEVEIALPSNVTNLKFVHPNLNFQSKIALKDSENEEVVDLEDSGLDKTYLTIWTDFYENKMGKKPRVFRIFPLPKLLAFIQDIYNSRWSFEDGLDENACWSKSKILRFSDYFYDFMEKRYQIKNISLKTIFDIISSLYANDESSLRVQIFTKILSGEQDATWKYFYLIEKLLLKYEPMDLKQYHSFLQILYPGRTKEIYDQMELEFTAFSKNHLTKEMIEEHIMHMIVTDIEPNYTFYLNCMKKIDIQRTGTLCYDDFDEAIGHILPVAGSNLKRVRYCITKADFEESQLPTLERLSYCACYVGLQNCFENNWTPQTMITAENIEMMTTVKVDDEEEKEKNTEKENAGKMNFKYKLNNDLVQKEVESALAGGSIAGKFLNQDDIDEEAAKLSRRVDMISQKEAGKFLGNNNYDAGESSDEEISTEAKSELIARLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBD8</accession>
    <name>A0AAD5UBD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBD8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="429" mass="50425" checksum="9995944383FA4603" modified="2024-05-29" version="1">MVSIGINSQTLTDLLNANEEKFVENMIEESSIIEKTSSEEQFEFNSNFYSQNLLHSLEDLSVNFKLTFEHYLEHINNFENFDTTVNSEHKMRLFLSLNYQEKMNVKISYLGYLNMNKSADSVDSRLILKTHKKKFLHLMNSMLDKILLAVNNFKENIDQKSLHKKEPEILPSPYYELKNQLKEMSENKIYSEQQYLSKYNEKLFNKQGDVINEDNLKKNPNRKRSVSFSDNDINESRISTTSQRTLGTSVSARGRNSDSYKRRGSVDERKNSLINSCGDAKQNNIQNQIDFYASRQNSLEKFKNFKFHYSTEDVTKENLLEGLKLEFTNVNMYLEWEPNLVLKKNMLDKKQNSRSFGESLNSVTILNLLKKLHLKETKNFTLTLRFKLFIDLKNFDLIFKFVENDALIHDEKFEEEFANLPLILDKVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBJ5</accession>
    <name>A0AAD5UBJ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Exonuclease 1</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">EXO1</name>
        <name evidence="13" type="ORF">HK099_002878</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">5'-&gt;3' double-stranded DNA exonuclease which may also possess a cryptic 3'-&gt;5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBJ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09908">
        <property type="entry name" value="H3TH_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000011">
        <property type="entry name" value="exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037315">
        <property type="entry name" value="EXO1_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF8">
        <property type="entry name" value="EXONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0228">DNA excision</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG-I" evidence="12">
        <location>
            <begin position="27"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="333"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="381"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU910737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3228373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="524" mass="59650" checksum="9AA2C50BA95025B8" modified="2024-05-29" version="1">MKEASEAAKGSVDITPQIAGKLIEELRIRKIDFIVAPYEADAQLTYLQKIDYIHFIITEDSDLLAFGCDNVIYKLDHNGDGFVINSSEISNMKEFRSYSHKKFLHLCILSGCDYLPSLEGIGLKKALKGLQKYDSGVKLIQSWIKFGKWMDAPYVRKDYLQDFEKAELTFKHQRVYNPVEKTLTFLNDPKISVTEYDIQNENFIGELISNNIAMEIASGVLDPITKLPLCQQVGTILDITEEIVLKTSKKYKGSVEKTESIFSNSSQNSISKQMHSQASVSSTDTCLEKFENISEVAFKSIQKQNVEVSRQVNTQKKTQPLINNNVVNEMFKNDRGKENYPPSFDKKPKKLPKTKKENKSNLSQLNSSGNPLYSSKEISFCKNLKDLKRKAENCLSEVEKKEKKLTIQSLAVKNEDDVTIKSSNNKNKLVTTIKNENLQDTIVYNFEKENDKENIVLDSNNDVDKGNINNSKYNNTIQNQKEVFLGLNQKFGNYKGLKNMESASSAFTTDLFKHPKVMFNSNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBM8</accession>
    <name>A0AAD5UBM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Blue (type 1) copper domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00920">
        <property type="entry name" value="Cupredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042142681" description="Blue (type 1) copper domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Blue (type 1) copper" evidence="5">
        <location>
            <begin position="152"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="249" mass="26677" checksum="6988212148FF07B3" modified="2024-05-29" version="1">MKFSAFTFALLSTTLTTVASAEYGAYDAYGAEPTQSPAQQNQQKQESYGNQSPQQGYPVKGVSQVENNVETKCVTSTITIPASTATLPPQTITVFETAVPQTMIRKCKPKQWKVKDEAELPPTKGVQEVEASEAGKYGQTEQTENTAETPAMEIIVGDGGLKFGPTEMKVKEGDKITFQFPGATHNIYQTTEEGGCEATEGGFKFPAEGLAKAGDTFEFTVPTSGGKKGLWFACKPHCEGGMKGSLLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBR6</accession>
    <name>A0AAD5UBR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="17">ATP-dependent helicase NAM7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">UPF1</name>
        <name evidence="17" type="ORF">HK099_000057</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs. Also capable of unwinding double-stranded DNA and translocating on single-stranded DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000097">
        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="16">
        <location>
            <begin position="60"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="15">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="15">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="15">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3227803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1007" mass="114189" checksum="E9FC13E8903261DC" modified="2024-05-29" version="1">MDSFNFNDFNVGETQASQYEYSEFTISSQSQSKPDLHDLLQSQLTIDNQELTFEEQNLDLKDLPDHACKYCGIFSPASVVKCVTCSKWFCNSRGNTSAAHIISHMVKSRHKEVCLHAESPLGETVLECYNCGCRNIFLLGFIPAKSDTVVVLLCRQPCASIPNSKDVTWDLSQWLPIIEDRCFLPWLVKVPSEHEQMRARPITNMQITKLEDVWKEHQEATLEDLEKPGVDDEPNPVLLRYDDAYHYQGIFGPLVKMEADYDKKLKESQTQENTVVRWDIGLNQKRMAYFHLSKLEQGDLRLAVGDELLLRYNGELHAVWEGKGHVTKLPNHISEEVGMELQRDHNTPTDCTHNFQVEFVWKSISFDRMQTSLTNFAVDENSVSGYIYHRLLGHEVEPQVLRVQLPKKFSAPNLPDLNHSQVYAVKSVLQKPLSLIQGKTVTSATIVYHLAKLNQGQILVCAPSNVAVDQLTEKIHQTGLKVVRVAAKSREALDSSISFLSLHEQVRNNDSNPELQKLIKLKDAMSELSAQDEKKFKSLKRQAEKEILQFADVICCTCVGAGDPRLAKFTFKTVLIDESTQAAEPECIIPLVMGAKQAVLVGDHQQLGPVILNKKAAKAGLSQSLFERLVILGVRPIRLQVQYRMHPCLSEFPSNMFYEGSLQNGVTIAERLRKNLGFPWPVPETPMFFLASFGQEEISSSGTSYLNRTEATNCEKVVTKFLKVGVQPSQIGIITPYEGQRSFMYNYMQSNGSLKKELYNEIEVASVDAFQGREKDYIILTCVRSNEHQGIGFLNDPRRLNVALTRAKYGVVILGNPKVLARHTLWYQLLMNYREKGCLVEGPLNNLKVFPLHFPKPRNYDEKDKNKRFKIDAQQHYQKGNLMPVKQQTPFNAFHDPLSGVDQNNIFSQSQFNVSGLQQLTQEFQSQTLGIQNSQMQSQSQSQISGYSQSQMSSQASQISYSSQSSAITNSQFEMMSQESFFEDYKSQALDFSQSSQIESRNSYTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRV4</accession>
    <name>A0AAD5XRV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_001878</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001580">
        <property type="protein sequence ID" value="KAJ3202373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRV4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF55">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3202373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="328" mass="37266" checksum="B45D31C8BD3698EA" modified="2024-05-29" version="1" fragment="single">MSVPVACEVLCTTQSLPALELSFAKQLIALEYKVEWIVDDLPAATANMFSVANKKVKEYEMGFLLGSYDEKTDKAYLNNHVHLKFLYENKDDLKYIVGFEVVTGSVDYGNNACSDDFLKLPPLEIGEDNLIKAITYTYSVSWHEEKGLKWGNRWDLYLSTQDSQIHWYSIVNSLIILLFLTAMVAIIMLRTLNNDIALYNEENVKEDPEDTTGWKLLHGDVFRPPFLSGFLSSLVGSGIQFSLTIFITVVLALTGYLNPAYRGGLVSSAIFSYVFMGLFSGYYSSRLYKSFKGNNWLKNSFLGYDHPVRTTQIPRQIPEQAWYLKSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRW1</accession>
    <name>A0AAD5XRW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001943">
        <property type="protein sequence ID" value="KAJ3200243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRW1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="252" mass="30209" checksum="DCE450EAD0CB8B69" modified="2024-05-29" version="1" fragment="single">LFEEEEKKVSKKKNQNKRKSLPLPITKKTIFNELDEQDVVETRCLKDGSEKLLKKKTDWKRISQDLILLEFQRQQKYNEELNNGIRDSGYYSNNTFHSEGFWLNSKFEEESERDLEDKSIKSECEEYLEISSVYSQRSFFKDVSYYQQYENLTVEEILGLKSQQKTPNDENLEYKGKQTEENLEYKITPTDKTLKLIETESNYHEEDFEDDEALRYLEFDKFHFPSETVKFENLCSTLSKVWEQRLENIARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT41</accession>
    <name>A0AAD5XT41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000919">
        <property type="protein sequence ID" value="KAJ3209871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT41"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="173" mass="19508" checksum="1FC5909D69995AB6" modified="2024-05-29" version="1">MKDLFNDKISQGYTVAEYEPYDDNPDEFAVILADKDGKSKEQFLNITKEKLNTALHSLGLGSVDESPEGLKKSSGRGRPSKSQNASHQNSSHQNTSHDSAATTRKSDGIDHRTDNIKKMTFKESMEQGAKIEDYSKHDEEHDNYMVKVKFDDGSLHVFPTLKGDHLREYQTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT85</accession>
    <name>A0AAD5XT85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_008265</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000895">
        <property type="protein sequence ID" value="KAJ3210365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT85"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052904">
        <property type="entry name" value="Acyl-CoA_dehydrogenase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041504">
        <property type="entry name" value="AidB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42707:SF2">
        <property type="entry name" value="ACD11 DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42707">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18158">
        <property type="entry name" value="AidB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adaptive response protein AidB N-terminal" evidence="8">
        <location>
            <begin position="17"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="176"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="295"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3210365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="69104" checksum="C65410C37BA994C0" modified="2024-05-29" version="1">MASGSQGFFQEPITFGNQFKEDLGLKKVLKKYLPKTVYSEIESDLIKFGDYVVCPKIMECVRLAEENPPKLTQFDNFGHRIDKLDLNEGWKFMKTVSAKEGLIAIGYERKQQEFSRLYQYAKLYLFSPSSAMYTCPLAMTDGAARLMEVSGTEKMKKRAYYHLTSTDPEQFWTSGQWMTERPGGSDVGNTETEAKHIQDKLYTIKGFKWFSSATDSEMTLLLARTVNNEGKFIEGSKGLSLFYGELFKNLDEKNEEKVLNGIRIQRLKNKFGTKSLPTAELELDGMKAEMVGNEGRGVAQISTLFNITRIHTALGVVSGTRRALVIAKNFSRKRRAFGKLIKDHPLHVINLAEQEVIFRACLNFTFFVIQKLGESEVLKTRESICLLRLLTPVVKSYTSKLCLNVISECMEALGGVGYIEETGIGKILRDTQVNTIWEGTTNVLGLDVIRVLTGRDGLECWNHYCEFVLKIIEKPQPKNSKIERKLFLNYNEILKSRFFTLKNFFEHYLFKKKDETLSKKKQNLNILELNSRKILFFFGKLTSLILLWENFLLSEKIDTDNSQEEFLDFNIFEKWLLSGVGESILVDGLEGCSIDYEIAMDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT88</accession>
    <name>A0AAD5XT88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000861">
        <property type="protein sequence ID" value="KAJ3210998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT88"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="405" mass="47561" checksum="9A5AF12185A17AF9" modified="2024-05-29" version="1">MDLKEVQHELSEIAKKISNVEGQQKMCADRIEKSKILINDYLNLKKLTVKELIQSEDTFFLSLQQEIASLQQEKTLLLQEKILLQEKASLQQEKTLLLEKEESLQQEKASLQQEKILLEQEKTSLANMQEIVFKRKMELESKGAKDSERPVPFKKYWSVDTFENTKIAKILEETFKDIIIDEGSLFLSADGVKSISAASDTYPHILIDKLNKERSKCLFKLWDAIQQNEIVFLLGSSGCGKTRSIFEFLSQYYGIYFTYKKSSAKRIPGSGDFEYTVFRIKATLKSKSWDSADSKQEYLDRFIKCLVTVRLYVFREFSEKLGERFNPELWLFIQLFPERYSDILFFEKLLDTFRHFDLNELDTLLQTLLEYFLEKNKTHLRILKNKEHLGIFKNKAHSRIPIFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTN8</accession>
    <name>A0AAD5XTN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small acidic protein-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000716">
        <property type="protein sequence ID" value="KAJ3213384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTN8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028124">
        <property type="entry name" value="SMAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15477">
        <property type="entry name" value="SMAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small acidic protein-like" evidence="2">
        <location>
            <begin position="160"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="228" mass="26071" checksum="398904969F013C13" modified="2024-05-29" version="1">MKRNIEDDHIEEPKKKLKKSKKSNPITESTVNSISIESNLPNKHEDIKKNKNERDIEITHSTEDADDSESILRENLSTEKDLDKKKKKKKKSKKSEKEKLHSEELSESKNLSIANTEIKKDEKLKSKSGIFVSDATKLNDTKTPDTTSSVDKKNQPWTDWGKASFDGDQARKDKFLKLMGYKKSNDDTSKDNCNNSSSKFVSMNDLERDFLQAKKLSEKLKRGSKAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTR4</accession>
    <name>A0AAD5XTR4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARC18</name>
        <name evidence="7" type="ORF">HK099_007410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000715">
        <property type="protein sequence ID" value="KAJ3213408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTR4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1760.10">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007204">
        <property type="entry name" value="ARPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036753">
        <property type="entry name" value="ARPC3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12391">
        <property type="entry name" value="ARP2/3 COMPLEX 21 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04062">
        <property type="entry name" value="P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016315">
        <property type="entry name" value="ARP2/3_P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69060">
        <property type="entry name" value="Arp2/3 complex 21 kDa subunit ARPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3213408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="176" mass="20103" checksum="7CD62EDA7F7F6250" modified="2024-05-29" version="1">MPAYHTQFTDENNYRVIGNISMLPIKTKTRGPAPIFPGDGEDIIDETINLFRANCFFRNFEVKGGGDRVLIYLTLFITECLQKLSQKPLQSQQEGLRALNTLAVGNFLIPGDGGFPLNALFERPANKVDSENMRNYLMQLRNEMAIRLCSRVFEQDKISKWWLCFSKRKFMGINGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU77</accession>
    <name>A0AAD5XU77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chalcone isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000587">
        <property type="protein sequence ID" value="KAJ3214846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU77"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16035">
        <property type="entry name" value="Chalcone_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chalcone isomerase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="94" mass="10589" checksum="953A6E8E944BB96D" modified="2024-05-29" version="1">MSPNDQAIIKKTLEYFDKEFPLSVVKEGTQLYFTKTSDNKFIVEIDGSEVMSIDGLGGKWMGERFFEAYLDNANPPSEVARKSFACGIENLVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU95</accession>
    <name>A0AAD5XU95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome biogenesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006554</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in ribosomal large subunit assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RRS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000574">
        <property type="protein sequence ID" value="KAJ3215027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU95"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007023">
        <property type="entry name" value="Ribosom_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04939">
        <property type="entry name" value="RRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="184" mass="21098" checksum="1C5E836A4E7AF033" modified="2024-05-29" version="1">MNDWLIELPDNMDPNTDVRSLAKEEKKGRIEKNLKQQKKNLEKSLPNNISKKTADVKKASDMIKVLSKPLESQTKRKEELNESIKNSKISTASMGKFDLKLKNEPEFKRGERGEKRKFAATTGNSKEEKHRTTDIVNKVLKSSGQEPMLVDSKLLKKVDKGKVVGEIKEKNKKRSEPKKKRVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUE9</accession>
    <name>A0AAD5XUE9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">NADH:ubiquinone oxidoreductase 30kDa subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006218</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000522">
        <property type="protein sequence ID" value="KAJ3215754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUE9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.80:FF:000002">
        <property type="entry name" value="NADH dehydrogenase iron-sulfur protein 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="entry name" value="NADH:ubiquinone oxidoreductase, 30kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004730">
        <property type="entry name" value="PRK06074.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004733">
        <property type="entry name" value="PRK06074.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="Nqo5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase 30kDa subunit" evidence="10">
        <location>
            <begin position="75"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="225"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3215754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="257" mass="30331" checksum="16F40EA3ACA6ACCD" modified="2024-05-29" version="1">MFSSLTSKRLYNLSKLNRFYSEVKSVNVGFEESTRQPSHSQINKKLQVYGDFITSCLPKYIHQFQVYKDELTLCIPPSGVLPVFHFLRDHHATQFKQCIDVCGVDYPMRENRFEVVYHMLSVRYNTRIRVKTYANEVSSVPSIAELYNAANWFEREAWDMYGIFFTGHPDLRRILTDYGFEGHPLRKDFPLTGYVEVRYDDEKKRVVAEKLELAQQFRYFDYTSPWEQTGEGKPSEKVNFAQLPEAEKKEKVEEKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUU5</accession>
    <name>A0AAD5XUU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005596</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000442">
        <property type="protein sequence ID" value="KAJ3217140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUU5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="99"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="96"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3217140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="182" mass="20823" checksum="EFFCB0FEF8074441" modified="2024-05-29" version="1">MMKNLEILKKEEEISPPKFEDETPRRFLASCSSLMTETNPFEMSLSLPPITNLPPQADFKDFNVNNENSEPNDFPQKVVLSQKSEVPTDSINTNNMTDAEKRKATLENNRKAASRCRQKRKEKILSMQEGIVTLSKDNVQLEELSKNLKLEIQELKILLLENKNCQVALKMGMDIKKIEAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVC3</accession>
    <name>A0AAD5XVC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002033">
        <property type="protein sequence ID" value="KAJ3199806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVC3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="205" mass="21544" checksum="7CED59675AA9AA56" modified="2024-05-29" version="1" fragment="single">TTCDPFVPEDTVCGVFAPGKSNFYQGQGAALVESYMSSLFLICPNMGASPALRDQFPLLFCLGAMGKCYGATYTLPDVDANGVPTNPNQIGAFYNTAKFGELAQNFKDNKVPLPCYEDCHAAMQSVIDCPAMNALGVTGNVNETACTGFPKRADDPTCVQKFGTGNGAKTAAPTPSPTSSTPSQPAKSSAFTNNASILIFFFITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVF6</accession>
    <name>A0AAD5XVF6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">U3 small nucleolar ribonucleoprotein protein IMP4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">IMP4</name>
        <name evidence="3" type="ORF">HK099_002700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001913">
        <property type="protein sequence ID" value="KAJ3200404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVF6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000001">
        <property type="entry name" value="IMP4, U3 small nucleolar ribonucleoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF2">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="82"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00040513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3200404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="285" mass="33424" checksum="4160887150B704EF" modified="2024-05-29" version="1">MQRRNARLRRDYLFRKSNESKEKLILERKQTIKNAIKAGTQIPGELRKEAEEIRKQLHVDEHITDHSTHIDDEYANAGVKDPKILITTSRDPSSRLQIFSKEMRLIFPNSQRINRGGYVTKEIVEACKQNDVTDLIILHEHRGQPDGMVVCHFPYGPTAYFTLHNVVLRHDIPDKGTVSEQFPHLIFNNFQSKLGLRLQNILKYLFPVPKEDSKRTLTFSNENDFISFRHHVFNKQGKQIDLMEVGPRFEMQAYEIKLGTVDIAEADTEWVFRPYHRTAKKREFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVU2</accession>
    <name>A0AAD5XVU2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">CDP-diacylglycerol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">CDP-diglyceride pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">CDP-diglyceride synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">HK099_004135</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000285">
        <property type="protein sequence ID" value="KAJ3220637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013882">
        <property type="entry name" value="Ctp1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08573">
        <property type="entry name" value="SAE2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15 24" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="18" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 24" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 24" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="22" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="22">
        <location>
            <begin position="1211"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="22">
        <location>
            <begin position="1262"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="22">
        <location>
            <begin position="1305"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="domain" description="DNA endonuclease activator Ctp1 C-terminal" evidence="25">
        <location>
            <begin position="2185"/>
            <end position="2221"/>
        </location>
    </feature>
    <feature type="domain" description="DNA endonuclease activator Ctp1 C-terminal" evidence="25">
        <location>
            <begin position="2230"/>
            <end position="2261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1153"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1828"/>
            <end position="1856"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="2067"/>
            <end position="2088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="2222"/>
            <end position="2277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="1155"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="1828"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="1842"/>
            <end position="1856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="2261"/>
            <end position="2271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00029893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00032396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00033406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF08573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAJ3220637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2277" mass="257859" checksum="63EF9640ADBD7FBC" modified="2024-05-29" version="1">MQRKKKSKGSIEDLHSNPSQNQSNSNNPSDQNINSEKDELDKTKEPSQPGVVLLSNESMSTKWKNWWVRFTWTCVMVCGIITVLLSGHVWVILVVIAVQAQIFKEVISIADIPSKDKKLPFFRPLNWFIIIVLVDAFLMPLATHHRFISLILYIIGFILFVMNLKKGHYKFQFTQFAWTHMTLLMVVCQSHFIINNIFEGLFWFVLPISLVVVNDVMAYVFGFFFGRTPLIQLSPKKTWEGFIGAFLSTLIWGFFFSKFLSSFPYMICPMNSFNPVSNKNSVCQPNAVFIPVQYYLLPSTQALISHLTFGKEVKFLFISSVQFHALIMATFASLIAPFGGFFASGMKRAFKIKDFGDSIPGHGGMTDRSSVPIKNINKLRKMHQCDFDSLARTVCDAIDILQENLHFVIKNEINEKVFKYQSTIASLEYFLGKNKKEELKLTNIYVKFFLYQQKEMIPVPQKKRPILFKPTRCTTSPTTPSPKQSKGTEVVKKSTEILSIDENVKVEIESKNKKKLVFSKSLITRIIKFIFIFSVNNKKKEKSIVELEKKIFFRDVQVNLYNFSLVNSDWNEVSNSFLWLNPNLSSTKDLSKLVYCSVLSGIRMQQQNAKFDKSEFSSMQTNPTSIDKCDLKIITDNNNLATIIKKKYNFKKNLNLVFNLKRSNLGLYLKRLNLIETKIDYQNRNFLKNLCSSFPHIQVLIWSSNPILESTLFEIFKNCKDLKKLSLSGPIISKKQLKNSEACTADDAEYLEVVQQGLARLTHLEILDFEDDITDSTESPTKVCSPSSFLPTPTESMGNFKVPSSNKQTINEEIYFGSKSSKGKSVSLDQLSGKSLTSNSKVKKLANEKLKEINKIISISPTLLQPSAVQPETNLSGEKQIVRDLPRLLKKSFVGVLEHLSLSGNSTSDLVVSIVRLSNGLKHALLNDCNNLTDRAAILLAANCGFTLTKISFKNCNLISDESIYEIRQYCHKLQYLDLTRTSITDKALEILADDLGEEDNNWEGLKGLYLEQTSICSDGGVKLDQYIKSFGCKLVDLNLLNCNFSLSKSESEAIFNTFNSFSDFSNFERFDCRNTFNLSSDYNGTRNSKVGKTSVSSNLVTKNGNGLEDEITKFVLNFVNLNTFNLGVLGVETTPFIEELYVKFPNEDEEKQDTQSILSKTDSSSNLTTSTKESKANSLNSHTFNANSIKNKLLREKQSKFLNKLTLNQTIQATGPITCVKFSFDGLYLAIASQDGILSIWHINNSTSANEIYFNNPYLVFTGHKDAIIDITWSRNNFIASSSLDKTVRLWHVKEPECLCSFIHRDAVASVRFHPFDDRYLLTGSLDSRLRIWAIHEKKVLYWNELPNNGYITAVSFTHDGSMVVVGTFNGDCIFYEFEELKYNTQISIHSNSNKKSKITAIEPILNDANNLGGEKSLLLISSNDSKLRVYSLRDKSLVCKYKGADTKNTQLRGCVDDDGKFIFCGGSDSCVHAWLIDCKNNSGVLNNIRAEANVKHSVEKFQAVEDQAILTCVQIAPKILREQVNEMQNIAPPMKDYSRSITSESSADMYKADLEGAILAVGDNYGRVLIYENVEKRLNLNFQNISFSSSLSPNSINFSPSYRNGNLSADQVSIQLSPTVLNYTPVKEVFPQNKNNTGIKSGLKKSSSINTFENRSSVSAAPERKNNRVSTLPINYRIPPMGSSSGQKKSLEGIGETHFLARTSDRSRVEVLNQNILKKNEILELKNLLLDKEKLLFDKDKVINEKKVDLITLKESESRSLDIISKLKKQLESFKVENDRLFACLSYIKKSENFKSGKVEDIISSFSKKRKASASLLTEENLNMKSESAGSVNSSPHTNSSTISLSKKTKKSISPNKKLKTNVNLLQLNIIENFNSPSKENTLQIISDKDHSDEIFVSNKYSARKKNSVTPKKKKFLQERQFDQEKLLKKAVNFDEVALNKNKPTIANNVESKIAESSALHENVSSKKINDEKLRNNFSFKEEKQITTPKSSNSKFETSSRYTISDVHLKEKDDLIINGSGLENWRDDVLVNDTEVGTTLDSITRLKSNEVSPSSQQHRVFSGENVVSSKNARRQNFSPGKSKVNNYKNQTDVRLDVLSSPLKINSKNEEVNYKLKNETLSNNCGDSSAISFEIATEVCPKKNKSKEENCQRFLEEKINEAMDSKYKSDFESIKKNNSDINYKYKEVVRGKDERKKLHGKDCECCSNYYKSTIDLPPLKEMGGYTSKDSRIQTNSRHRGEERMASPPGYWEPEFPSTQEVKKLKEEGKARNRNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVZ4</accession>
    <name>A0AAD5XVZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003878</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000260">
        <property type="protein sequence ID" value="KAJ3220968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVZ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF44">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="170"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="201"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="524" mass="59296" checksum="5C53D6EE2E04F12E" modified="2024-05-29" version="1">MFFSITSLRFILENYSKLIKSSTKPEKLEEELRKEIQDAQSFDEFLDLVSQLDVLLNNEEWRSNPVSNLYDYKLIQQRLEQFHNDINGLEEIKDLLRTGMLRNFAGIHNPKLFSRSFSGTKHLIEKYLDKLVSIMYTIADMPPSVKRNWSLKHKLDFFAELKQTFGQTALILDGGASFGLYHIGVVKVLIENDLLPKIICGASVGALIAALVCIHTDEDLPEIFIPGGISLEAFAQKSAKHGLRRKFTRLLKYGYLLDIKVIEDCVRSNVGDITFEEAYNKTKRVLNITVSSSKKNEIPKVLNHLTAPKVLIWSACCASVAVFGLYSSIDLLAKDKIGNIVPWNSSTISWSDTYYDAERAETRISELFNVNHFITSQASTATNSFVTPLLSTIIPDGLNETGITTKISNLISQEIKHRINQLSYLGVIPKQISSLFESLSGNSSSNVLIQPHIVLKDTMTIFSSPTHSSLDYWTKKGEQSTSRTKLEYTFDEKEQEKVERIEKLSRKKSMENFKGKIKRTGSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW64</accession>
    <name>A0AAD5XW64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Chromatin modification-related protein EAF6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MEAF6</name>
        <name evidence="12" type="ORF">HK099_003678</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000243">
        <property type="protein sequence ID" value="KAJ3221226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW64"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015418">
        <property type="entry name" value="Eaf6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13476">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09340">
        <property type="entry name" value="NuA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="118"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="174" mass="20310" checksum="CCB756934E2B585E" modified="2024-05-29" version="1">MTEPKSKLSPEEQAANIEALALTEKELKDLIDDKKQIEKRLVDLETNLYNLETTYLEDTAGFGNIIKGFDSYLNGRAIDKRRSRFFETDRIFSNSSTTTQKSIDLKEREERELLLQQQNSENEFNENEHSPIPFNKKKKRNIDLDGTFNNLGENSDSNFTVSNKRKRQRVEDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWM8</accession>
    <name>A0AAD5XWM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000646">
        <property type="protein sequence ID" value="KAJ3214145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="153" mass="18459" checksum="4EE43B56FEEAFE3C" modified="2024-05-29" version="1" fragment="single">IYRENEESYMDELERRFFAERFNEQFETKQRVFPSKIENLVKKMFDFRNEVLVQEGELHPFLMGNYFFLLFNLISPFENVQGNFILGSILRDDFLLNNENPPFFNLNTKSNNSLMYLKMVGLVLENFNDVEKKQKFYEYCLDSYLADWDSVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWQ4</accession>
    <name>A0AAD5XWQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S acidic ribosomal protein P2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPP2B</name>
        <name evidence="5" type="ORF">HK099_002592</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000187">
        <property type="protein sequence ID" value="KAJ3222193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWQ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002182">
        <property type="term" value="P:cytoplasmic translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="111" mass="11163" checksum="7F218B04CBD9712E" modified="2024-05-29" version="1">MKLIAAYLLAQLGGNATPSAKDIKKILSSVGIEADAERLKTLLSELEGKDINEIIAEGSSKLASVPSGGAAAGGSAPAAAGGSAAAPAKEEEKKADEEDEDDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX42</accession>
    <name>A0AAD5XX42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosolic factor, phosphatidylinositol/phosphatidylcholine transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SEC14_1</name>
        <name evidence="2" type="ORF">HK099_001715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000151">
        <property type="protein sequence ID" value="KAJ3222959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX42"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="89"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="302" mass="35403" checksum="E1D070E198EB51A8" modified="2024-05-29" version="1">MSTALDQYPTFGRLGHLTEDQQQQLTEFKTLLTTLNIYDSEKYDDNLLLRFLRARKFNLEDTKVMFENYHNWRCEFGVDKLISEFEFPEYPVVKKYYPRYYHKCDKLGRPVYYELVGEIDVTQLFKVTTVERMIQNHVLEYEKLVNYRLPACSKKVGRYLEQSTTILDLKGVSISSFSSVYNIVKQISAISSNYYPEMMGKMYIINSPFLFTTVWALVKPLLDEVTVNKIHILGYSFKDKLLESIDAENLPKVYGGNCECEKGCQNSDLGPWNDGSVEGYPKKEFERFNIQFDMGQSQKFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY80</accession>
    <name>A0AAD5XY80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Leucine-zipper-like transcriptional regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LZTR1</name>
        <name evidence="6" type="ORF">HK099_004440</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000312">
        <property type="protein sequence ID" value="KAJ3220211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY80"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00185">
        <property type="entry name" value="TNFRSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042102798" evidence="4">
        <location>
            <begin position="20"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter substrate-binding protein PnrA-like" evidence="5">
        <location>
            <begin position="98"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="961" mass="107497" checksum="0077AFC9B56CBD1D" modified="2024-05-29" version="1">MNVTLVLTFVCYIIQLVASKENVLLLVPGSIAVLKGCNNFTCTVKPVEDTSPPQIEALITGFTHIVFADINNSFAASAEVVPSKYINYICDMLKLFRYMDKTFVIFDFIPKVISSNLQIFMFKLEEVGFLAGVTAGLISTKKVVAVISGLPSVENKKHVNGFLQGVVYSCPLCKVQYQYSKSNTNYTLAIENAKVLNDAISYDVIHVAMQSGSFEVLNWAAKEKIYVIGANYDNLKSPSAFGQYLLLIDPIMEFYLNSIIKQYDVAISESLKNKEKNIISGFFELGSANGGVAVTENTSRTYSLFSNQTRQIEVVSNKVECTSSLLFTKKKFLFNTYTRLQNNSIEVGVNGSTGYLSGLARGFNFELCFVYSIVLANDTFTVLHPFGDKAPPIWRNSFTLGTNNLMYVFGGLISGIESNTLYALDMNEYKWVKMETLSDVIPDARESHAAVYFENNLVIMGGMRGHQTFCDMWKFSTESKSWSEIKLDMKFCRGRFAYTLIDHLLYIFGGFDEAYAIRNDLATIDVLSGTVTLMKPLTDLKPPVLLDSMMIAFDSNVFVYGGSNLTDVTNQFYKFNIENNLWTLLNPRGDPPPVLAKGLMTKIDENRLMISGGISANSILQNSNFFFDIKNNIWKYGEISNLPSSLVSFSGFLYRQPENPCMWKENPNYSLCNVDSQTSLILFGGYESEGVSDKLIKYQIGPQRPPLSSCRPGYYLAIDIYDEPVCTKCPEGSYNTNGNGICESCPHGGVCPGGSEVNVAVGFWQDANSSTSFPYIYKCPIDTCCSIAQGCNTTQQCKYGTTGALCSECSEAGHSLWVNEWYDHCSYWILVEVIERVALASIAATYSYPEIDYAWGYFISIVVIIILQQNNVYRKNIENWSKLFLMLTMLGVAGIKLINGETDVTTDPTMQSLNQTSYNTHWKNFWLSAPLILAAFRIISDKLIRFFPKKKAVHLDIEKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYQ2</accession>
    <name>A0AAD5XYQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005766</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000464">
        <property type="protein sequence ID" value="KAJ3216718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYQ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3216718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="255" mass="29775" checksum="C869654FC21A9DE9" modified="2024-05-29" version="1">MHNFIAKLRSLLDDKTYQYYITWSKQEDSVIVLNSEQFSTQVLPLTFKHSNYNSFVRQLNLYGFTKVNRNYHRQNSLSDEERAKIPKEFRHQFFIKADPTLATKIKRKNPKRICTSHNNSDLNSDGSASSELHSAAFNDFEHLTFKFPNDDDFGSPTKTDLHSAVVEEHEQFTFKYRNDFEDETPTKTDLYFSTNNSDHSEQSSTTESTPSLNYVSVFLKSSKENLDRTNDDIEEISPRSLKVQSLLAPIRKKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ83</accession>
    <name>A0AAD5XZ83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar protein sorting/targeting protein PEP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VPS10_1</name>
        <name evidence="5" type="ORF">HK099_005002</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000373">
        <property type="protein sequence ID" value="KAJ3218575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ83"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031777">
        <property type="entry name" value="Sortilin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031778">
        <property type="entry name" value="Sortilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006581">
        <property type="entry name" value="VPS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050310">
        <property type="entry name" value="VPS10-sortilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106">
        <property type="entry name" value="SORTILIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106:SF27">
        <property type="entry name" value="SORTILIN-RELATED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15902">
        <property type="entry name" value="Sortilin-Vps10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15901">
        <property type="entry name" value="Sortilin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00602">
        <property type="entry name" value="VPS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="VPS10" evidence="4">
        <location>
            <begin position="1"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3218575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="483" mass="53611" checksum="519B814425F7D7F1" modified="2024-05-29" version="1">MQGVKGIALANIVQDEVHSGITKKVGTKITFDDGVSWKNLEVPEVGLNERAFSCTGSDCAVHLHSFTERRDPRDQFSSPSAPGLMVGIGNVGNSLLKYDDGNVFVTRDAGLHWKEVAYDAHMVEIGNRGTVLVMVYDEGPTDVIKYSLNQGNSFSSLTIDMLKGNKIRVKHILTDGLGKSPHFIIFGDVVGSGDTKGKLLSLHLNFESAWPRTCIFNKAEGAESDFEKWSPFVDKSEAECILGEKTTYYRRKEDVNCFIPEDLPSELETIPCLCTKEDYTCDVNFIKDANGDCVLMEGRQPLYSPCVNNKMYLSNGYKKQTGNGCSGGVELENKKSVWCGGDDPGNKNAMGFWGILGWIIFSFTLSGIIGYIILRYKHLFFTHPGRIRLPVDNYFSENTSRYASTFSEKVGSGIRTGLVYTLEFVEVVYNSGRKGFGWVRNKVSGRGGRGYQPLRNFDFDSTNAADFDNSLFDLDEEVEGISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZB5</accession>
    <name>A0AAD5XZB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZB5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="333" mass="36969" checksum="078B3E1666D503F6" modified="2024-05-29" version="1">MQQVPQVSKVQDNTLPPKELSDRKQQKRNSIFGFKKQSASSATLSTDVPEGTLVDDEKQKKKRFSIFQKKPQTENLSTETNAAPISTSAVDENSHEETGKVGEAEGNSVEEIKTEENAMKKIFNRFSTKKAVDNSVPPSTSNDNAVHEIAKESELKDFDLKKTEPRDNEAMDGTKGIKSSDTESKDIKEPKAEAKDIEPNTSTTIINNIEQTKQKNTEPSHFKLLLKKFTTKREKPSVSTKENVVAEELQSDDETEVPPNSPTTAENNESDEKRFQLKDFLRKLSLKKNQQSKEVKPVGETKKDDEAMEVSEAVASAAAPLVVSGDSKVETVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZC9</accession>
    <name>A0AAD5XZC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_006730</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZC9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="11">
        <location>
            <begin position="205"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="10">
        <location>
            <begin position="512"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3228105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="599" mass="69413" checksum="5EAA934FA4187035" modified="2024-05-29" version="1">MAKIGVNRFKKFIFTQYARAALGGSGCLTLLLGGKVCIVKPKIVNKITPTHSTQANTGILFGVMHVIAETMHSMNPVQKKVSNPRKIAIAPSVKCQQRCESCRFVHDFEKRGYRKKQRLSNKKWTFNCEDNNYKITSQNISEEEENVNEKSKFYRVDFHTTENNPLEKRLGFRPSAGISQNLVSFVKNNDSKVRAQFSSTDLSYLRELFNQLKCDTLELKRKERVLNTISRKLKVNADIFGSSVTNLGFKGCDLDIFLYLSELPEPFFIKYDLSRKHRHNLQPTRFLTLPDQYASGQKPNITKVAKEISKKLRNSRLFHNVLSLPLARIPIVKFKCSETLLQGDLSWSQCLGVYNSKLLKTYSEYHPFVEPFVKLIKFWAKQRRINVPHKKSLNSYSYTLMAINFLQNEQIIPSLQELYSDERRRVVLVPELDNPFKPVYGYNFQLEKNFMDHHLNAYQRFFYASTPRHYDHPAMFRRVDISFVEGKSHDNFKRCSLSMCNLSDSQCHEIFDLLLKFFNYYAYEHFNGGPKVISIRKGYVLKDITFGLGNSIDKPLIIEDPFILSKNTASFIDISLIKPEFVRAALLFARGSFEEIFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZH2</accession>
    <name>A0AAD5XZH2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GPI ethanolamine phosphate transferase 1</fullName>
            <ecNumber evidence="1">2.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MCD4</name>
        <name evidence="3" type="ORF">HK099_004658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000335">
        <property type="protein sequence ID" value="KAJ3219581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZH2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16020">
        <property type="entry name" value="GPI_EPT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007070">
        <property type="entry name" value="GPI_EtnP_transferase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037671">
        <property type="entry name" value="PIGN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250:SF0">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfatase N-terminal" evidence="2">
        <location>
            <begin position="156"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="390" mass="44203" checksum="13695ECE12E9274D" modified="2024-05-29" version="1">MEPVFPPKNSPADRLVLFVADGLRADKIFENKMKRAPFLKEKAIQEGVWGVSHTRVPTESRPGHVAIIAGFYEDVSAVTKDILPMFSHGTSKEGKMEMFMYASDAEDFTTDGSVLDTWVFEKFDEFLDNASKNITLFDQLSQKKICIFFHLLGLDTNGHAHRPFSETYLNNINSVDEGISNVVKKLEKFFNNDRKTSYIFTADHGMSDRGSHGDGHPDNTQTPLIAWGAGISKPHKYDSGSDPEDGLTAKWDMTDKARIDVNQADIAPLMSTLIGVPYPMNSVGRIPLKYIGEDEEFKAKASLGNAKQILRQYLVKEKEKSQTEIFFKPFKKLLQWELKLKTIEELIAKEFYKKAELKSVELVLTCLDGLRYYQTYDWLFLRSIISTGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y075</accession>
    <name>A0AAD5Y075_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">XRCC6BP1</name>
        <name evidence="9" type="ORF">HK099_008665</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Has a dual role in the assembly of mitochondrial ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000098">
        <property type="protein sequence ID" value="KAJ3224274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y075"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="168" mass="18977" checksum="68963376D8A3C743" modified="2024-05-29" version="1">MDEKVKTLVTGIKDSGVEVEFGKYIKCAHCPSKLFGFFENSTGLTICQNNSKSQYITESTLVHELVHAYDFSTATLNDNNLSQRACSEVRASNLSGDCDFIREFLNFSDGFLKKFTGQKVNCVRRKASFSLSQCENLDKCETDKIVDSVFNECIANIKPFTNEQFKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0W1</accession>
    <name>A0AAD5Y0W1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006397</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000055">
        <property type="protein sequence ID" value="KAJ3225676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0W1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="552"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1196" mass="138419" checksum="9E108056A00AC948" modified="2024-05-29" version="1">MFSNLKFFLAPNLEEKTKLFTLITKHNGSCLDSQSSADYILVDKNSTESNSKLELAVDFITDSIINEKLLNTNDYLIQNIIEKKALELSAEELRKTTEKKDNEKKVFLNSQGTPITFRIPGVLNTETKKLGSLIEENGGILVNATEKPDILLVNPEVSTNADGVIYSFVTDSVDAGVLLTVDEYKMSKHKNFSPIFKAPLERIPFTSKDNYILMRHYLENDQKNSLAVWRKLAEDHSTHSPQSWKNRFNTLTELERNEIIKKLERQNNYDDFTYQATRQNNNKVASISSTNFRDSLKRTKTPFSFNDEEILLEHFIISGRNNSLKTFKALEKLQPHHTAESWRNKFKNLEFKEKRIAAKENALNKKKIVENCVIDTSFEKKNYDSPNSRTSNENSEGTISHSLGSHVSSIEEEEKNEKLCTAIDTNNEVNPFSAKLETADVIKVSEIHNMQEAAEVLSENSPPINATNLDKNNKLETEFKDAVNGLKNEINSKEILSEIRDKEIEEIQDEENNAYLFNIYRYLELDTSSVDENIENPKEKLSTCLSNDEKVSCGNNSIDSNSDESGKLKDDKETNLRDKMSLNNKSDDEFVAPSKKRILTRQHDAEDYSDDAQLYSPLISKYNSQSHHDIDSDLIRESETPNSTTAGGTVKKKRFYSGKKDNVPEEQLSITDSAPEELMSFIDGEKKKIFNSLTFQEENLSEDSEKSDDVIIKKEESPLVKKEMKSQIWNNHGFLKFDKFDKFQLPSRNNKIPTKKDTNKKVGAENLNAFKKKTVKENDLFKRDESNFANLRTEIVERNNAFLKKRQSEEKSSALEQKFNEDDNEQLNDEGTDLIPLLSSTPLYFKSGLRIPKKFNLDNSIYLPSLKLNGQYVEIFDGDGNEVQVLLNELGVAELFLKNSNEKEDDKNLKKIIAVDGKENNHLDHISNLHYTKKKKKGIFREEIDKLSTDNIYGKKRSWTNVEDYEQVEEEFNIKRESLYLNSKKKREPEGELSFTQLDFGFYFFHKFALTHFFFLFIFSNNDLIIDPLGRTPEKGKNILRCSRRKSNISLSKKQNFLQNEVKNFKKELEILKLKYGNNMVKKALHLCSNNMHVAKEILLNEFKLEKLKSLDKARLFILFHLILFTYLFRVFTPDEDFIILKGDLFSLQDLTKKKKNREIISLRKRYVNLDIILNLSFFFIFQDFFSYKKNKPIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1C9</accession>
    <name>A0AAD5Y1C9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001152</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1C9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019727">
        <property type="entry name" value="ATP_synth_F0_fsu_mt_fun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051848">
        <property type="entry name" value="PGIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059:SF30">
        <property type="entry name" value="OS06G0587000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059">
        <property type="entry name" value="POLYGALACTURONASE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10791">
        <property type="entry name" value="F1F0-ATPsyn_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="431" mass="48233" checksum="206AA0B9F36D8E90" modified="2024-05-29" version="1">MNFTRTFVRSYSSIIPPPISGMREIGKLTSKYPQAHPDLFAKMKNFYAKVPKGSRGAETGELSFTKLYYNKYIKTDSGAPILHILGIMIPLGYYIAYFKGGVSLLAYKENLETFDTVLKNKYLTNLEEKKKKKKMKILILFTLFLSTISRSADRIAEEIARTTPVPLNNSIIDANTTNSTLSSDCKILVSWLPTVFNKTDCCSSAVNLIPGTAGLLKHISCDSNGRVTSLNIGTPYWKTVLTNTALPKELGALNMLEYFALTDSNITGTIPEEYGNWKNLLGFYVFNNSLTGNIPNSFKNLRLLNEIDLTENKLSGQIDPFLFRYWTRLTGFWVDDNLFSGQIPKTLQNVLSLQGLGLSSNSFIGEFPNLRGLRFLSTGIGETWLNLGRGLDNTCQLEDLGDVCLPPEVDIPEACNFDENIRSKLKRLNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1S1</accession>
    <name>A0AAD5Y1S1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000416</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1S1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="351"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3227743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="667" mass="75346" checksum="9DC733B6B7309018" modified="2024-05-29" version="1">MSGADFVFSWWLKQWSDTSSTLITLQKCGNVTNSNNNNTLFAPEKPNSFNLNNAYNEPAALFVEIPNIMGDTGYYLKYYAMIGVIVMIVNNLNMIIQLFGVVVASRKLHSKLLLRVLNAPIKFFETTPIGRILNRFSKDISGIDQNVMYTIGAFIQTLFRICAILILICAVTPYFILFLIPIVFVYIIIAKKYLKVSRELKRLEAISRSPIYSQFSETLIGVSTIRAYGQEQRFLDEAYKRLDSNHRAYFFLWVSNRWLSIRTDLISSFVVFISGAAMLYGHLPPGWAALTMSYSLDLCEAFLWVIRSHADMEMAMNSVERVQEYSTIEQEAPAVIEGRRPPSNWPTAGVVEVKNLYVQYSPESPAVLRDLSFTTKKFEKIGIVGRTGAGKSTLSLAFFRIFKFAEGSITIDGIDVEQIGLRDLRSKLTIIPQDPILFTGTLRSNLDPVGDHDDAEIWGALKRVHFLDSLQDVSASNEEVTPDSSEEGTVVEDNLINIDETPFEERPVFNEENCSLLSKNSFDGAESLNSSNSNFRISLDAFVSENGSNFSQGQRQLLCLARALLKISKLIILDEATASVDNLTDLRIQETIRSEFVNSTVLSIAHRLRTVIDYDRILVLDQGEIVEFDSPYLLMEKRGYFYKMCEESGELDDLYEAAKLKHDSIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1Y6</accession>
    <name>A0AAD5Y1Y6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1Y6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039646">
        <property type="entry name" value="ZNHIT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15555">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15555:SF0">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="335" mass="40425" checksum="E9A9F893B47691E0" modified="2024-05-29" version="1">MEMLERVLEKQKDEQQHNNFLFQQEEEEEENLENRFSNFDFNNASETEIFDKLNEEEKREFNKILFNLESKKEEEVSNLESLMKESLIWEPWWLNPAFNNFIDNNESLLIEDIEVEKKEMDFDGIGPKVNKEDPDFLKIIKVLPNEKLFYNLIDLSFTYSYVLRYFNGEIFENIEDSVNLICKVSGILGKDQEGLFENEEEAFVTLKVKLLEHNLLSVETILYILQDVIVLLSNKIIIKKFLSEFENLFKEQYNGEVRNNQEKKVEKKMIFKKIKKINYYFNLMGYFFNKKNKKKFKFHLDKVLEKELLEQKDFDMEVFKFVNLNKKNKLFVEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2T2</accession>
    <name>A0AAD5Y2T2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Threonine/serine exporter-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005420</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2T2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="4">
        <location>
            <begin position="155"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="4">
        <location>
            <begin position="304"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="465" mass="51817" checksum="A756AC084EAAB34E" modified="2024-05-29" version="1">MTFNLDCYPEVCGLNDANPLFGGTLKKSSEKEFKVSSLKRKITKHKETLSRKKTLQDATLQKQFANSVNEGEAQEVSNSSYQNDPPLSHPNVSENEITYFNNERTSATLKKMICGYLTSSESHIQNYDYDGDCDSTNRLTNFDDVDDITYTSKMDFLIELAKAFILYGVPSHRLESQLHRVSKAVDLKSEFFVLPGVIMISFGNESSESSTHLLKVISGYHMAKLSAVNQLCNDIIDGKASCIEGLYTLDSIAESRFGLNRVGLVSNEDVDIENVKKETLRSNSSVPQRKNGFFGAVEQRFCDRYTFLFIFPIMSFTLCILGFSGTWVDSVFSAFLGLVVGLFVALVAKFPKTSSILEFVSAFFIAILTRLFQLYCYKNGICLNVTITQLSGLSMLLPGMSLTFAITEISTKNLITGTVKLFFALFTAMMIGFGLFMGDSIKFLIKIPNQLSCSVSSTAHIPPFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3A7</accession>
    <name>A0AAD5Y3A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042210992" evidence="1">
        <location>
            <begin position="19"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="140" mass="16384" checksum="554207A8DEDA3D94" modified="2024-05-29" version="1">MLAKFVFLVLALSVTVLAHSKHWYKHHYNKGDLSEKEYGYKHKHYGHKHHKYKHREYLALDEEDIDAQEGNDSGSEKESYGYKKKKHYKEKESYGCTNGHMKCKGTGFNTCDHHTWVYRECGKGTACKQNGKGVYCDYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSN7</accession>
    <name>A0AAD5TSN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40s ribosomal protein L44e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL44_3</name>
        <name evidence="4" type="ORF">HK099_003378</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002216">
        <property type="protein sequence ID" value="KAJ3198985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSN7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3198985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="105" mass="11981" checksum="9FDB24D1E8075811" modified="2024-05-29" version="1" fragment="single">VNVPKTRNTFCKGSQCKKHTPHKVSQYKTGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTNKNVVLRLECTVCKYKMQMSLKRCKHFELGGDKKTKGAALQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT25</accession>
    <name>A0AAD5TT25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002263</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001736">
        <property type="protein sequence ID" value="KAJ3201381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT25"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009668">
        <property type="entry name" value="RNA_pol-assoc_fac_A49-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06870">
        <property type="entry name" value="RNA_pol_I_A49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3201381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="107" mass="12487" checksum="1BC2E4914169EC24" modified="2024-05-29" version="1">MKFRTVNPRDLLKLITEKKIEINNEDEEKLEAKNFKVFNGCPLPLVEYFCEKFTEIVEDEFGNKKMLISDKLKDKCLAYIFCFSLILADFKVDISIISKDLGINLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT45</accession>
    <name>A0AAD5TT45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001706">
        <property type="protein sequence ID" value="KAJ3201571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT45"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="63" mass="7424" checksum="A8B22E2FF7DD3F05" modified="2024-05-29" version="1" fragment="single">ETFKTSPNPEPERNNNAVYDFCVAGCEYELSEYLNRDSGKWLMVHYEHEMDSTLFFQLKSAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTG7</accession>
    <name>A0AAD5TTG7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001887</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001587">
        <property type="protein sequence ID" value="KAJ3202326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTG7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF31">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="52"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="163"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3202326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="27856" checksum="930129A4C4223B3E" modified="2024-05-29" version="1">MPEIALKKLFKLKGLASPLYGSIFENAVIFASYTFFQNQINNFNDRPKDNELSLPNLCLAGALSGATISFIMTPVELIKCNLQVQDLAKVNQGKLKYSGPVAVIFSTLKEKGFTGLFQGQVGTLMREAVGNAAWFGAYETACAGFIKRKKYLNKSSYVSKKDLSNGELMAAGALAGMSYQAAFFPADVVKSRQQTQEVLTGVNKSFVQISKDLFKEQGIKGFFRGFTLTILRSAPTSACIFWSFETLKRNFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTK0</accession>
    <name>A0AAD5TTK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001827</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001560">
        <property type="protein sequence ID" value="KAJ3202518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTK0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="261" mass="30698" checksum="7B8C163EFE6ABA46" modified="2024-05-29" version="1">MELKEKFYILDDQSGCISLTLNQSHLEDLALKLGDYVELIGYLTINSHFRDYVVIVEGIKVVEDVTQELLYDLRLINNYKVCYLIKKKKKNIDIKKKSLPNYNNDNDKKFKFCDEFQKKKKFTLKNTPVVPKKKENFETFRLMESNIDKKNKGHIAELKDLALGNFENNINVNNIGNMGKNSTVNDEFDDDIFMDFLPDDFDESQIIQEQIMKELKMNKNGINKAELENKLRNLGETLFREIDSLLMLGRMYTKEDKFYIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUG5</accession>
    <name>A0AAD5TUG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="1">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010002137">
        <property type="protein sequence ID" value="KAJ3199326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUG5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="215" mass="24286" checksum="7A5E0012276B51EE" modified="2024-05-29" version="1">MANTVRRHKEKMVLPPISVVICDGVEDITIKISDEAGGFPDSYINNLWSYLDENQSNFTDVKGNTCLSFKDEFDFPPVAPSFSLPFSRQMARYFGGDLEVVSMEGHGSDTFIHLFKKDTELENISDVIGMNKLVIKHKKENSSKTLEKRDSPTLLSDSTKNYLIKNNNNTKIKNQLDDLITSPSPVSLDKPKLEIKNKATAFNNEWVLDLNLIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV76</accession>
    <name>A0AAD5TV76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Exosome non-catalytic core subunit rrp4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RRP4</name>
        <name evidence="10" type="ORF">HK099_000577</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001135">
        <property type="protein sequence ID" value="KAJ3206269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV76"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22525">
        <property type="entry name" value="KH-I_Rrp4_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05789">
        <property type="entry name" value="S1_Rrp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000038">
        <property type="entry name" value="Exosome complex component RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048565">
        <property type="entry name" value="S1_RRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF4">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21266">
        <property type="entry name" value="S1_RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exosome complex component N-terminal" evidence="7">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="RRP4 S1" evidence="9">
        <location>
            <begin position="68"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="8">
        <location>
            <begin position="162"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF15985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3206269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="288" mass="32189" checksum="7710930DAD7B8B70" modified="2024-05-29" version="1">MSVQFYSANSIDKSRKIGKVTPGEIITDDQQYMRGHGTYSNEENLVASLGGVIERVNKLISVKPLRARYNGEIGDVIVGRITEVQQKRWKVDLNARQDATLLLSSVNLPGGVQRRKTELDELHMRSFFVEGHLLSAEVQSFFQDGGASLHTRSNKYGKLRNGSLVTVPSALIKRSKSHFITLPCGVDLILGVNGYIWVSKHVENIVNNDPDSLYSNENEVITDETRETIARVSNCIKLLATHDVVITNTMIVYTYDASLQYHPKELLKFDVGEQIIEIAKAQSKELGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVT3</accession>
    <name>A0AAD5TVT3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000838">
        <property type="protein sequence ID" value="KAJ3211377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVT3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="98" mass="10826" checksum="14AD5812F11943DF" modified="2024-05-29" version="1" fragment="single">HYSIPSKGKKPDVPTTKLDARIAMALVVRMVDNGVDVRTVVEVKFASIRKSSITAKIVKDLEFVHMESTRATAKTVKVLAFVYITSVKLIVKNGIVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWN5</accession>
    <name>A0AAD5TWN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000679">
        <property type="protein sequence ID" value="KAJ3213752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWN5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042079189" evidence="2">
        <location>
            <begin position="19"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="237" mass="24725" checksum="DD94A1617113E740" modified="2024-05-29" version="1">MKSRTLLFLLVFVGSTFAIELDIGVAKVGLLEPTTPTSAPAANPSVSIAEPQKIPTKQPQSNISNTVPSGASPSSTNQISTNPQNPSPQVVPQVNTPTASSTSGQSDNAVVSGSPSSSANSNPVVFSPSNNLDFSTTNSNSIKSPLSNVDENFENNNAGGSTAKPPLTSDDNGDENKGDDKTTQHSTTQSKVDGSKQRDAEKDLDVSAMVGNKERKPSVNPLIAPWEVETGLCRDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWT7</accession>
    <name>A0AAD5TWT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000699">
        <property type="protein sequence ID" value="KAJ3213545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWT7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="3">
        <location>
            <begin position="467"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="139"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="499" mass="55844" checksum="1C5AA19782FDCF15" modified="2024-05-29" version="1" fragment="single">VKALSNNFQPFADLDNAEELERTWKICTKAKDALENGNRFENLSWRLWHRHQTMSRTTPNKFRKLSEQTTFKLQKEKISCVKSENNNSAILQKNINKNSSHIDQTFSPLLITVEKIQQQIQQQTISKYSQQAFTSKKLQASPSQQASPTQSVSQQSSPTQNVSQQSSPTQNVSQQSSTQNVSQHAPPTQQSSPSQQSSQAHLTSVLVQPAASLLQQTPSKKITTLKNKIILSSQTDQFAYPVNNCPTLFDNLNNQPSPTNSLASNTYLSPELNSRLLQSNVNHCDAQIMSLLADFPFKDDVCFPFMNTTEADFTNSSQQVAPIFNSSNNSQVVGENLDFLHRWTGDQIQFLQPNTPPLLSSKPTADTSNYLNQFSTSHYDLLLNDFFSQGQFTEISQQPNSISTQNNNLIEQQLQQQSNSFLSVINLQENDANNVAKKNTEAIRQQHVNKRPSAKNSTTKSQNAAHSSGPEQCQNCGVNQTPLWRRSSNDELLCNACGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWY8</accession>
    <name>A0AAD5TWY8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000762</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001193">
        <property type="protein sequence ID" value="KAJ3205574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWY8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3205574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="63341" checksum="B63B0487E7432559" modified="2024-05-29" version="1">MSNTSIKEIFQNFVQANTVELTTQSFNLLVTALNFPKDYPAFRDAVLPHVNFRMKTLFTNLDNKFNCYAELRKHSEKSENKNVLVSGGGPCGLRAAVDAKLSGLDVTLVELRDDFTRHNIIKTWKATIDDLVGFGLTTFVPGIQLHGHLHLGTREIQTCLLKSALIFGVKIFFNRGVCGIIDPSVTMNTENNSSKSWKVWTLPAAEAKIYLKRPTAAPEVSLTTGASDTSNLTKYSKCDFIEYNSVDDTIILKDLDKVNALPNTVEIIEFNTLLIAEGESSVLIRRLGFDRCITKFNEAIGLVVNLDFTQEAMKPSAPERKIPEIVLTRAAAQWRDTPLGKIADIGIEFENIEYMRGSTHFIAASTKLKNLHTFQIVKDIKPKVKESLNINNLDLEKLRKLGLQIALELGLPKNITLSEKNGVQIFDFSAKGQCADTLKFFKSMNENLNEALILPIGDSFQNPFWPQGLGINRGFHSSLDGVWSAYQYATDISKDIVENERKFSYQMCNWGSNSLDASLKNWTCDPISRYSVISISRAIYLREKIDGKPSTIPQRIIEFVGVENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX34</accession>
    <name>A0AAD5TX34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000664">
        <property type="protein sequence ID" value="KAJ3213937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX34"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052775">
        <property type="entry name" value="IUN_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46190:SF1">
        <property type="entry name" value="SI:CH211-201H21.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46190">
        <property type="entry name" value="SI:CH211-201H21.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="364" mass="41223" checksum="E31D44AB10178C74" modified="2024-05-29" version="1">MEKLENIIFDTVLMIKKKKDGGIDDHTALICLGKSPSVKICAVTTVGGNVDIDKSLLGIKTTMGLLNLTNVPLYLGATLPLVPDGFHKSPPKWFGHDGIGNISKNADFLRDYFESNLIKENREDFASLAMIKIDPLFLSKVKEIYVMGGTLYSKGNSSKVAEFNFHYDPESAQVLFSAAKKHHKKFKLNKPIINLVTWEVTVHHPVSLKLLKELKKTKTLEDSRKKIFNYFLKFIEISSPPTTTNEHKENPKKNMGDEGEENLVKIAVGSKVLTERITDLKYDQSFKAGDIILPDFTAICCFLKKDVVLSYKDFDIEMELEGRSRGGNSFGWNPWHQDMKFVRVFLELDSKKIDDIFTNTFFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXV8</accession>
    <name>A0AAD5TXV8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alkaline ceramidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ACER3</name>
        <name evidence="10" type="ORF">HK099_000477</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001108">
        <property type="protein sequence ID" value="KAJ3206668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXV8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF3">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3206668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="29386" checksum="87F5A621E5DD5536" modified="2024-05-29" version="1">MNSTTQYHGPVTSSVDWCEENYEVTPYIAEFFNSVSSLAMMIISFYGIYKHRNLDILTKRFFFLYLAIVVVGIGSVLFHGTLLREFQALDEVPMIYAALTFDFILLGLFIYAVVTTLAVTILTGNAQFRTFHISYGIAQEINIVLFIRLYWITKNDGVKKMFKVALVTFVSAVAAWLTDLLLCEYVNGSENSILPVNFQLHAVWHCGISSAVYFFSLAALLAASEKIGKPATIRYHFGIIPYVSNDTNLKNNTLKTFKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY08</accession>
    <name>A0AAD5TY08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000582">
        <property type="protein sequence ID" value="KAJ3214924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY08"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="4">
        <location>
            <begin position="502"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3214924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1134" mass="131030" checksum="3E2362FE06CE66C0" modified="2024-05-29" version="1" fragment="single">NLQSKYNATWALVTGGSSGIGLSIVKKLAKQNINVVVVALDDELLKNSEKELKSEFSTVEFKFVGVNLGAQNPEDYMIPMVKATEGLDVNLVFNNAGYIQVGLFSFTDSKQISANINCNAISGVNITHHFSKEMIKKNLPGLISFTSSPGGFMGSPMASLYSSTKSFLTSFASSIAGELKDENIDVVVVHPSPTNTGFYKNAGLLTALKFFQSTATDPSVIADSIFKSAGRCVIVDQGYYTILNRIFLKFFDVTVMTELMTAFVNGQSDFKDVRILTGIGHGSHSFRLNFILEKSNLTTVALPTTTSIISEKQPLFNQIEQKKKLNNTVTVDGHEIPTKKKFNLLENTSKQYEIDVFLEDPPESFNLPDDTEYVMEPTSFFSVLWSNLFRTIYSGVGAWYTQMYYNVFFLDHHRFVLIDNDPHPTKFLAVLSVVTKFPVEFLDSINNTIFRAGVMGISKDVQVAEIDDEIYFEERFELRKKVFRDFCDHLKEKILNFEDFENYGHKIFHKIVKKIRKNKKQSLQLLNFQKKKYNNNSSSSNVLQLSLILREGETRKILNEDGLIEMLKTFSEFEVNIYRFSQLTLQKQIEIIDQTDVFITMHGAALTHLLFLKKNSFVVELFPYAFKKKIYSNLSKILSLNYLSWQNSDIKKSVLNFDIVKNNRLTFMPKKLIMQLPINWFNMDSKNYWRNQDTLINLDEVKYILKNNLLETFKNKNQNSDVRYFIYLPWEQLNNQIIGLKSACAISNFLNRTLVIPDLGFRNPNSNTHKKLPSDFVFYKPADYIWKNIDRYLNSTNLLSLPCKQISLQNFKSLNKDLSINNIMYNHLSDETTSINQVKDYFQHVLKLKFNDIVFNPSIYYQLTKQEIFNFYGNNNQRVLAVSSMFWHYDFGYKQVFPLKNFHNYLHYGNENENLVVSDNLYEQISVGITYSERLMDLGGRLIKNIFKDVEEMNHQEYLSIHIRSGDYLEKCSKIFENLSCFINSTALIMENIEKHFDGHLINGGILYISTNEENFREVFKDLHVDFGGKFKKVLFLEDLLEDSEVDEGIEDNINLFDDNNKTINEIKDLVYEQDEEEKFGELPLRMDLDKLDQSILDQIICVNSKGFIGNYHSSFSRSIIENRIFKNKSWNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY30</accession>
    <name>A0AAD5TY30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">BAP1</name>
        <name evidence="11" type="ORF">HK099_005989</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000493">
        <property type="protein sequence ID" value="KAJ3216168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY30"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09617">
        <property type="entry name" value="Peptidase_C12_UCH37_BAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000009">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041507">
        <property type="entry name" value="UCH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18031">
        <property type="entry name" value="UCH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="10">
        <location>
            <begin position="197"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="59"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3216168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="483" mass="54975" checksum="5BFA80449C541DD9" modified="2024-05-29" version="1">MTGSLKEEAEERTKKRDTGKQKANLPSSPTKSSPTKSNLADKETALDPNMEQNNLSELLFEELPEEDEEEDIDFLPLSDDEYQSDEDDSTDDEEANKDSTIPEQQLLPSSSSTPHGKVLYQVNEDDLDEEVDGLLQETEEFKGEIGGELVDGLRSGKLRNRIYKSAPKRGVVTVEKNKEEENDEDSEAQKKRPKLWNWCLIESDPGVFTEMISKFGVNGVQVEEIIDFDLLNDLKPVLGLIFLFKYENNSSEKENKYSPEFVSFDSNLFFANQVINNACATQAILSILLNSSSVDIGDTLREFKDFTRHFPSDLKGEAISNSDIIRNVHNSFSRSDPFQSDEKAVSKEDAEDLFHFVAYLPINGKLYELDGLKPGPIFHGDCTEENWIDTVRPIIQNRIATYSSTEIRFNLMGLIKSRKLILEDLISKETDVNKQIILKDKLSYELEKIEKYKKENQRRRANFIGLIYACCKEMGKKGLLDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY44</accession>
    <name>A0AAD5TY44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000568">
        <property type="protein sequence ID" value="KAJ3215118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY44"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="291"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="43756" checksum="667139A8FA743C02" modified="2024-05-29" version="1">MRNYPASKPNIVNAPLKDITNKQSSSNAFNPLTTEFRQKFQVDSSFSNKKSEEIETFIAVLGLSAAEKSHLIRHLIGLDECEIGTKVQEYSFMLNNKKITLVDTPGFSYSMEDHSKVLSSLISHFKNNSNKKKLEGIIYAQAIGEREWTSDFAKLSEQFQVLLGPDFYPRINLLSSKGEKTNLSVEQPGNNKGKVNAEDGKQSKQFSAVMKKGAKCWEGSNLNDFKKVIEYITELPSGEEVAIKETNNTDSSLAQQNEMRLALIHKAEVLKIRNQNQQDMKRMELQHKQEVDKLSQIIIDLKLKLGEVQNELDAANAIIQQSNHHTAPQQTQNTLAELSLQEDVADLLQLQLHKNPQNWDYRCKAITIKGKRCRNNIHCPHHKLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY87</accession>
    <name>A0AAD5TY87_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000551">
        <property type="protein sequence ID" value="KAJ3215334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY87"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042287229" evidence="1">
        <location>
            <begin position="17"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="174" mass="18728" checksum="D19393656889F3EA" modified="2024-05-29" version="1">MKVMILLIVFFQLILADKPANGFEICKNDPNKCYEHCAKNPVACAQELSGPFQATIGDAYVKYLKQKAYDSAIAAGKSKRSAAAIAGWAGRNAKAYADMICKFPILTFYDIFEMWQETGSVQQALSIAMCANGIAAGTTFALTGFLGPTVGSGAGFFARNLGKPFCGKMYNSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYT0</accession>
    <name>A0AAD5TYT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007375</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000708">
        <property type="protein sequence ID" value="KAJ3213458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYT0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="496"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="558"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="244"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="440"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="607"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="452"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3213458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="650" mass="73063" checksum="2A33F677E5648D34" modified="2024-05-29" version="1">MKKLIRRNSVQVNKSSLKKGWKRNKAIAREYSDALIIYFLPVALRDFSGNMLLVGIQAALKRMVPKRTTCGIYGVLLLHPLQPNNAIPPHQFLSALSEEQILDRSKLGGFLYVPIADPSAKTRRNNNFQPFADLNNAEELERTWKICTKAKDALENGNRLENLSWRLWHRHQTMSRTTPNKFRKLSEKTTVKLENEKIGAKGKESESPVVQVISSGFQRESYSPLLVPTESQQNRASPVIIKAPSKPLQHKTTRKKKIQPPKKKSSQINSTQPSSLNIFETLQQRSPTNSVASNTYLSPELQAKLVQSKIEQTNFFNQTDDAKLMSFLSEIPFSDDIFPFINENEISSTQEQQANNYISAAPSNCNVAAENLDFLNSWGGNSQYLQPPTPQFSSKSLSNSTYLSQFSWPGDSLILPNVFAQNQFDDLTPSDPQTCFSTNLHQMQQQEHRSTDFFTSKENSSSGSKAPKQKQTSVKTVAPATSSVKIQNPSHPAGLEHLNSQCQNCGVNHTPLWRRSSNDELLCNACGLYFKMHSFHRAKPKNPIPQPSKDSNGETIVSCFNCSTKNTPLWRRDGAGNMLCNACGLYLKLHNEHRPLSLKTDTIRKRQRYASFDPDTGESISSKKSKKQNVNNPPPTGATITGLFNEYNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYT6</accession>
    <name>A0AAD5TYT6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SS18 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000743">
        <property type="protein sequence ID" value="KAJ3213125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYT6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007726">
        <property type="entry name" value="SS18_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05030">
        <property type="entry name" value="SSXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SS18 N-terminal" evidence="3">
        <location>
            <begin position="17"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="310" mass="34472" checksum="1D463A9FCD60FF96" modified="2024-05-29" version="1">MSKLNLNLPSPNATMVPELNSHTLSILLQTNKQIIKILVDYQANGWTNDPEYIQYQKRLAMNLQYLAAVANTSTTKPIAAFIPPITPVLIPEKLKNFQQQESLKKSNSNNNTTNNSSVTSKNLTEIVESLNPPLMVGNSNNNNATSNKASSNSENVYVPVPPFILPADADLNIVKPITSINKFAGSTSTTVISVNNKNELPPTKMIIAPTIENTSVWEEEQKVKNLILKKISSYGASLDEEITFDDNNVKFNEVQEEEGGPLEDEEEDEQSNLAEEEPLLTTALNDEEDGDYKPKNEFFDTNSDLFDFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYU0</accession>
    <name>A0AAD5TYU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Integrator complex subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">INTS6</name>
        <name evidence="4" type="ORF">HK099_005733</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000460">
        <property type="protein sequence ID" value="KAJ3216798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYU0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057413">
        <property type="entry name" value="Beta-barrel_INTS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051113">
        <property type="entry name" value="Integrator_subunit6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12957">
        <property type="entry name" value="DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12957:SF2">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25462">
        <property type="entry name" value="Beta-barrel_INTS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="5"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Integrator complex subunit 6-like beta-barrel" evidence="3">
        <location>
            <begin position="253"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="619"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="937" mass="106814" checksum="CB3B777D9354502A" modified="2024-05-29" version="1">MVVHVFVIDTSASMNQEFQRGFSKLDCAKNAVEQFFKWETKRNDNYNNKYMLVTYDDFPSCIKSYPEQSISHLLKELKHLKAYDLSQAGQTMASIFDFLNVYRFRKETIGSGRYIGNLETTLLYWFTDGGTFYQGRGSEVGNMSDNLSLPGLTSAGASTYIEPFRWDQRLYTILLNTENIQPRIITQLRSMSENMGGECWSIDNIKSLIHCIDNCMGGVKPLHPDCQPQRSICAIEGVTVFFEEESNQPNRLFGKALVYANSVNSTRNFPIPENYWVESVSHSPVPPPRTAHPKLIFSLQKANLYSIPESFPVDRFHLDPCYLTVKLEELSNQKPGTCVPLFVKNSYIQEGLGHPCGFLKFSTQERRVSFYILPYNFPRLFKLIDQVYKKGTVIKQSIPMHWSSSFYEYLKDTPSYYWESLRRALKQIGLAENIMPKQFVESKVSPFPAILSTLKANTKLEYSRIIKSKISEAKVGKITEMENSGIGGICENPFDVERSNLLATLTSASLYITEKLASNNHSENKLKKKKKRLSQLELDELHSLPVAEMGNYIRAASSIQKLKDPFEDEETTKQREKSMFGNPYKKDTVVSIDEADEAQSFDSDVSVKSSEREDDEESISSGSTVKSNSSTSSLLRRSKSGSIRRAKLRSTSPTPTPISPVINRVPKLALTLSQNFMEMSNYLKTIKNMEEKEALLLLYPAFVEKGQLPVSSVKRKISNEPFLTNDKSLAVKISTESKSAFPMGDDLLIPNLYDFTKVDEGMDDRAEKDYDKDEFYFGESGKFNNNFYTDSTVTTKFISEDDVQKSKRIKIGKSETTDGLLDIYDSTLDTALNKTNLNNNGLKENDENADYKKLLLILENEESAKNYIFKIFRESPNGKCFDSKSVKSFFLTEFSRQKVKTLVNCLKAEDTSKNLLFYDLCRNLSFRMKLCQDLFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYU1</accession>
    <name>A0AAD5TYU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000428">
        <property type="protein sequence ID" value="KAJ3217434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYU1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="149" mass="16502" checksum="5D3A77AD0197050E" modified="2024-05-29" version="1">MFDDPLLSSSPPKLHVEHENDLNLLNNSIYSSEDIQEINPLGDTTFDTVDSYKHQDLKENSEAELDKSNHINSIFNKSSVNNSAHSSNNTGNMSKPSTYESHYDKSKDLAPCCAIDKALKDISVESYIPKLLSSANFSPSKPIIVITDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYW4</accession>
    <name>A0AAD5TYW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005687</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANT/ATPSC lysine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000455">
        <property type="protein sequence ID" value="KAJ3216879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYW4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905706">
        <property type="term" value="P:regulation of mitochondrial ATP synthesis coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610:SF11">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3216879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22693" checksum="402A12D3DD5F3063" modified="2024-05-29" version="1">MEEIFPFAESNELSNDIEDLKNPIPFTLVNNIPMDGTNFIAPYVAVPESVAIEAIKFANLNNEDCLVDLGCGDGRILYLAHQEVSGLKSFGVELDPYLAMFASNKVKNLNCIIIEKNMFEVNLLELKATCLILYLLPLGLEKLKSNLKEWFEKENTSNFKRIVTINYKIPDCEHEFEKCVISLSNSYNLFSYQNIIGNTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYW8</accession>
    <name>A0AAD5TYW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007264</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000691">
        <property type="protein sequence ID" value="KAJ3213643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYW8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17782">
        <property type="entry name" value="CBS_pair_MUG70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051462">
        <property type="entry name" value="CBS_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108:SF26">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN DDB_G0289609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="6"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="73"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="179"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="256"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="127"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3213643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="452" mass="49587" checksum="054BC6D635D3D30C" modified="2024-05-29" version="1">MTVSSLKPNPVVALHESATVFEASSYMAAKRQDAVLITDSEGHLTGIVTDKDMTYRLVAESLDPKSTPVSYIMTQNPVSVGSSEGATEALNKMVNGHFRHLPVLEDSVNNDEQEGGVVGVLDITKCLIDALAKLERVNASNEKLNQAIIEVENEFQTSKQSLYADFLSSQLGMMDLGSLIEAGGVPPIVSLNSNVLQAAMVMLQHRETAVLVLDTKDITPHVYSGQIAGIFTTKDVVLRVLAANLDPRVTPVMRVMTPHPDTANMDTTILEALRKMHAGRYLHLPVVCSDSGMLEGMVDVLKLTYSTLDQLNNLTSDSGGPVWNKFWESAAMSEVSGHSYRSRNSRRKSRRNNPQTPSEDGGSVIPDDSASMFQPRKALTDDEDSQQYSGMVGIPNNQVQLHHNQVAASVHSNSTPTLLEKIQGGELFLYKFKYREVVYRFISSSVKFQEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ85</accession>
    <name>A0AAD5TZ85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000526">
        <property type="protein sequence ID" value="KAJ3215689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006150">
        <property type="entry name" value="Cys_repeat_1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00289">
        <property type="entry name" value="WR1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1822"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1822" mass="190169" checksum="D2F32D6A0172F493" modified="2024-05-29" version="1" fragment="single">MVMECDANGVTYTQCKSDQSCYDGKCICSPVGSKCYDGITSQYCDGISENWTAPTVCEIGKVCDPLNTIGGQCKCKADQCFGEKIKRCNVDGTFSSASDCPTSGDTCQGGNNALIPGTCKCVEGTSKCGDDGSAVLKCNSDGLWQFSNSCGVGYTCSSGQCKCTGGKKCINADVNKEYTCVIGTDITWKSTECPAGTYCLGNDESGLNGECKCTHDQCIGDQLQRCNKVAGTFDSPVVCPNHSDNTPVKCSRGDENSDATCKCAPTGTKCDVTALDSSTVLMCAKDASHWITEVCPNNKKCSGDVNGFGGNCNGGVCTQDTCDGDTIKKCENKIYQPSEACPLGLRCQGSGTPSDPAVCKCSPGAKKCGGDEGQTVLICNTEGSAWTATTTCGTDQICRSGSCFCSPTESTRCNSETEAATCKDSAEKWQKHTCDDGKTCFLNDLGSTCKCTHDKCDETVDGNFAAAASCNAGFTCRGQGTSQDLAACKCDPGFSRCDITNKNVETCNTDGDVFIPVSCGGDQICAHGGCICNKVGTKCLDSNNEATCTIGSANWVPKKCNNGENCVGDVNGFGGTCRCSHDVCSGDQLQVCAINHLGFGTLSAPKECDPFLKCTTGVDTDVCSNGVPTSKCRCTPGNTRCSETLGTSQQYTCASNGLSWIPSPCANGEKCKGNDPSNGVGGYCKCDADICDANGLVNVCENNHFLTPKSCGSELQCSNGKCVCKVPGNSCSSDNTSVISCENGAITTQKCNSDQTCSEGKCVCAPFGSKCNGPISTQSCDGISENWSAPILCETGKICESQNNSGRCKCKADQCQGEKIKYCNQDGSFSTAENCLISGYKCKGGDNAFVPGKCQCTEGDTKCGGDGVTVLRCSCDGIWETSKTCSSGYTCTSGQCTCSGGSKCVNGESTKEYSCVAGIDLDWKPKDCSVGTTCLGNGSNGLGGSCKCTHDQCVGDKLQRCNKSSGVFETASTCPNHSDNTPVKCSGGDSSTDAVCKCAPVGTKCDTGGASWTTSTCPSGKKCSGDINGLGGNCDGGVCTQDTCDGENALTSRSLPQKYVLTTLSVKEVVQQQIRQNANVQRIVKSVEACKSDGTAWVVASEQCAADQTCNLGSCVCSPAGSTRCNSNTEVGTCVAGNVNWGKTACDDGKKCITTDLGGSCKCVQDKCDASGKIVKCQGDGNYGTAMSCEAGFSCKGDGTANNPATCKCTAGATRCDVTNKIVETCNIQENAFVASPCNNDQICENGTCICNKVGTKCIDSDNQATCYSGVSSWEPVKCKSGEKCTGDHEGYGGKCSCNEDLCAADQIRYCSSGHLSDPVSCSPFLKCSTSYDGDKCRCNPGQTRCENGVQYTCNVSGLSWTPSACGYGETCIGNDALTGVGGSCKCSNDICDANGKLVKCDNGKFNSARSCDAGFSCSSPSVGNSFCKCDPVGSRCPINELNPLTVQKCVSGGTSWTSTACPVGEVCTGGDLYGNGGACKCIADQCNGNGLLRKCVNGVFSDPEPCPNALTGNSCTGGNNADIPGTCVCNPSSCPANKSKCDSLSGYCKCTSTLLTDSCGDGYKCDSTSGYCSCSPKGSTKCAGNDVLTCSDLSQDWVRTPCGEGQICDKGKCTNCIDNPRPACTSVEYPEGSDASKRLFENPALFPYGLYWCDHASGVHYHCAPDGAKFGLFGAVKNSQGTYGPGWTPINCAATTFCHAQAAQLLSKTQKSYFTTKLCDYAANLNIKYTEDGSCVDKIFDYEPFCKAQDPPLTFCPYVQPTVKSPGGFDEYLLTCSPSKFGRDKIALLYRKKVRELWEEEGYATRKAEIETLKVYGDEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZN6</accession>
    <name>A0AAD5TZN6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Plasma membrane ATPase</fullName>
            <ecNumber evidence="13">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_000197</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010001032">
        <property type="protein sequence ID" value="KAJ3207786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZN6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000042">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000211">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="638"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="704"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="768"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="800"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="14">
        <location>
            <begin position="3"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3207786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="887" mass="97215" checksum="7716ADE4C48E9FAB" modified="2024-05-29" version="1">MAGLNDSEVAERLLKFGHNEIKEKKHNPILKFLGYFTGTISVLIEIAAIVAFIVRSYEDFAILAGLLVINACVGFIEEAKAENALDALKNTLALNSKVFRNGSLVEIESVNLVPGDVIALRLGDIIPADCRLLGITVTGEISESPLQIDQSALTGESLPVSKGKGSIAYSSSICKQGQMLAIVTKTGVNTFIGRAANLISITTDAGHFQKVINNIGNFLVIITVVMAVTILLINLFVKWQMDEKGHIKEPRERRSFNEALLEVLSLTIAAIPVGLPTVLSVTMAVGASQLAKKEVIVKRLTAIEELASVSILCSDKTGTLTLNKLSFDEPYLANKGTTATDFVGTGIKNTAEELLLDSYFASEAGAQDPIEFAIRNAAESRLSILQNRKEVNQIPGFRVTNFIPFNPNSKYTEAKVTNLETGEVFRVIKGAPQVVIRMCGGHKEASDAVIDLALRGVRALGVARTIDPEMTKFEVVGMIALLDPPRHDSADTIKECKKLGVSVKMITGDQMIIGKEVAARLGMDRTILDATNLNNPDIDIEAITDCVVKADGFAQVIPEDKYKVVELLQNRGYLVAMTGDGVNDAPALKKANVGIAVEGCTDAARSAADIVLLAAGLSTIVDGIKASRAIFQRMRSYALYRIASTIHFLLFFFFSILFYDFVLPNKLILMICILNDAATLVISVDNAKINKRPDKWRLGQLMTLSTILGILLCVISFGHFFVAKYVFTNLTHGQIQTIMYLQISSCPHFVIFSTRLTTHFWKNMPSTVFIVAIGGTQVIAMVMSIVGWKVLKAEAIGWEWGFSVMAVSLVSFMLLDFVKVWVINSWSFELTAKLWPVKSRKMEVDRRRGQKIVLERVKKNFGKIKILSKVIHACALFKHSGERHLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U083</accession>
    <name>A0AAD5U083_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="13">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">RET1</name>
        <name evidence="22" type="ORF">HK099_007233</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 24">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000686">
        <property type="protein sequence ID" value="KAJ3213687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019399">
        <property type="entry name" value="Parkin_co-regulated_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10274">
        <property type="entry name" value="ParcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13 22" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="18">
        <location>
            <begin position="56"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="205"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="422"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="20">
        <location>
            <begin position="524"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="21">
        <location>
            <begin position="606"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="15">
        <location>
            <begin position="687"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="1061"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1148"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1162"/>
            <end position="1174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3213687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1340" mass="150252" checksum="7CFE920B32B58C3E" modified="2024-05-29" version="1">MATNNYTIGRGKGSSIFETDTNSRDDLRYWKKDITKKIDKVEDKWRLLPAFLQTKGLVKQHIDSFNYFIETDIKQIMLANSTILSDVDPKFYIKFNDIRIAVPESYDAQTQITNEVTPHECRLRETTYAGFIYVDINYTRGSKVISKRNIQIGRMPIMLKSSKCVLANLPPEDVVKLGECPLDPGGYFIVKGAEKVILIQEQLSKNRIIIETDRKGFIQATVTSSTHEKKSKSYVASDKFGKIFLKHNSLSSDIPVFVALKGMGIQNDREIVELICGDDPDLLDFLIPSLEDSAKSGAKTQLQALEFIGGKIKMTAKSFRIGIKRDWVEEARDLLAGTVLAHVPVPDIDGRANFRPKAAYIAVMTRRAGQLLGLLFEDFFKSWISQVKRTVDLQLKKSNRTAQYDAATALTQTSRMRAGITQVLNRLSYISALGMLTRINSQFEKTRKVSGPRALQTSQWGMLCFSDTPEGEACGLVKNLALTAHITTECDDEPVKKLLFILGTEDINLLTGLDLYNSPQTYLVFLNGILIGVHRNHRLFVSNFRKLRMDGRIGPFISIFTQIQQRQINISSDGGRVCRPLIIVEKGKSLIQEDDIKDIICGVKMFDDLVKEGKIEYLDVNEEGDQMIAVFESDIKYDPDESEKIERLLAERLLLEKTTGIPSKAPLPVPTNTTHLEIAPLAVLGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQLTRMDTLLYLLVYTQQPMVKTRTIELIGYDKTPAGQNATVAVMSFSGYDIEDALVMNKGSLDRGFGRCQVLRRYGQVLKTYPNRTYDRLVSVSKADIDDEKYSIIDEDGIAHVGERIKNDMIFINKQSPQETSSTVGATDIVESTTTSFKPTPSTFKYPAEAYIDSALFTTNQDDQTLIKVKIRQTRRPELGDKFSSRHGQKGVVGIIVPTEDMPFADSGIIPDIIMNPHGFPSRMTVGKMIELLAGKAGVLKGELQYGTCFGGSKVADMSRILIENGYNYSGKDYVTSGITGEPLQAYIFFGPVYYQKLKHMVMDKMHARARGPVAVLTRQPTEGRSRDGGLRLGEMERDCLIGHGASSLLMERLLFSSDAYDTEVCKFCGLVGGWQGFCTFCQSRSGIVEVKIPYACKLLFQELMSMNVVPRIRKNKVDVNDRKNKKPHSQKDSKSFTKPSDKLNPKTMDCFSKTKFSSNFSSTYSKGGFPCRLVHGSIHHTLSWTTHPSAMLTFNPLLVTLFEGLIETNFPYNFIVKEAIKEFIESENSFNKILPILSLLIRPLRDGLTKNLKTSLEVLKLLFNKMENEMLKFFPNLLQPLASRALKGEDGVEVMNTLRFLEITIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0M7</accession>
    <name>A0AAD5U0M7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000284">
        <property type="protein sequence ID" value="KAJ3220642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0M7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="1">
        <location>
            <begin position="291"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="512" mass="59263" checksum="DC9EE3C45E0C1E40" modified="2024-05-29" version="1">MKEYRVVSCIILSIIFLSYLFFPNSSSPADVQKVTVKEEKVVTKTVIKIVPTTVVSTTSVLITKTVTVTVTLPPQSSKSSEKLLENNLASNANVEEELSPILLMDNYETVNYKVTLPDAPSIPRFEEKKYFDPVVTSIGTDEDTKLFRSKNYDSYLKYVKNVNKLYEGNKNLTHTLKKEFKSTYQCVGKNNVYNHPERRNCVFNDICYDTREQNFVYYQPMELPVFSDKSYGPIFNFNENETQFVKLNALPFESYYFTPVVKIGKPEKKDSVILKNQHVLFSTWAPEMNIGHFIYEELLSTLIAMKKLNMFDVESQLLNYQGDFNYNEDDEIDFTSEYYRDGKNFKGKSKIYKRLSETFTHGITNKKIIGLKKYLKEISQEEGKPLVCFKNLVVASAGRQFWSYEDNHNENLSPIFFEYRNNILSEKFGLNPYHKPKKHLITIVHKTGSFFFSGKHAHDIYNIEEVTDHVTSKFPDIEVNLVEISKLSFEEQFKLLLNTTVIITPCGSGLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Q8</accession>
    <name>A0AAD5U0Q8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inhibitor of growth protein N-terminal histone-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000308">
        <property type="protein sequence ID" value="KAJ3220307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Q8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor of growth protein N-terminal histone-binding" evidence="2">
        <location>
            <begin position="11"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="270" mass="30573" checksum="87530B3AA370642B" modified="2024-05-29" version="1" fragment="single">MSFNSFDYATYLEDYIATIENLPSEIKQIYQEITEKDKAVKFKNQEQHQKDLNLRKIIKQSTLTEEELNLKFIKESTNSNKEAKLKKHKKNAANPSYVSIGIKDKNFLSLEQLDIYNAILAEKLSLNNIIEEKIKLAERAFAMVDRHVKRITNDMEKFIDQDTNHYNSTYNGNSSSLNLLAPPSLSVSNSNTDLNGLSEIKSIIPVSPNPAGREGRQGSNRPVRKRPANPKSRKNTNTKSKEGDGLAEDEDFYCTCRQVSFGAMVACDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0U7</accession>
    <name>A0AAD5U0U7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UBR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000450">
        <property type="protein sequence ID" value="KAJ3216986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0U7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040204">
        <property type="entry name" value="UBR7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="15376" checksum="FFE9A9B21592E764" modified="2024-05-29" version="1" fragment="single">MIHEQSVITAEDFLTNQLDLEKQAKKLFKSDSNKCAITEKKKNQKIYVCLTCSKENTPSGLELFNKRDFKCDCGNYKMKNSCELFKKDLLSSEDFETNVYNHNFCGKYCYCDTAYDVENDVMFQCLFCQDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1B8</accession>
    <name>A0AAD5U1B8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003704</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.9" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000245">
        <property type="protein sequence ID" value="KAJ3221199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1B8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017939">
        <property type="entry name" value="G-Glutamylcylcotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12935:SF0">
        <property type="entry name" value="GAMMA-GLUTAMYLCYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13772">
        <property type="entry name" value="AIG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617939-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="180" mass="21055" checksum="F732AD86E10F43B3" modified="2024-05-29" version="1" fragment="single">ETMDNQISFYFAYGSNMCKTRLLERKVEYVSRSLAYLQGHQLEFTLPHKKLRNMEFIKDDHLIGYANVSKVSETTSNVIDQFCKSSVVYGILIELKTKEEIYKLDFFEGIEFGHYTRERVQVQRIKEGREETVEALIYFAGRNLLKNGLKPSKKYMNYLLGGSDLLPTDYVDNLKQLETH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1E8</accession>
    <name>A0AAD5U1E8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">O-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_003665</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Sterol O-acyltransferase that catalyzes the formation of stery esters.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000241">
        <property type="protein sequence ID" value="KAJ3221257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1E8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF7">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000439-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3221257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="479" mass="56172" checksum="3CFD7882298FB406" modified="2024-05-29" version="1">MHSNLKPRKTNKSKRYQELDDNQMEHNKENVDLINEKYCRVEKEGKALNTTADKKKTRFSHNYLTHTTIRASPLSKESPEQNYRGFLNLLILSLFVLLLRLAIENYTKYGLLITLPKLTGSKAEDFEWCFYSMTYTLMSVSFAFFIENIAILTKSENLTFFLNVCNLNLCLIVPIYISWEKIPYPAISFYPLLIATIVWLKLISYALTNNDLRLELKQGNSVAAAEDSDSKNFKIENSILCPTLVYQMTYPKTKVFRKRFFFKRIGEVIICSTAMMFLINQYASPTLENSLQHYKEMNILRLFERLLKLSIVSLLIWLLMFYAFFHSLLNGLAEVLRFGDRRFYQPWWNASNISEYWRLWNNPVYDWGKRHIYLPLVINHKVSSQNAMLVVFLISAFLHEVLVGIPTHNISGVAFFGMIGQIPLIYLTKWLQKLSEKYSKTKSEVFTTGNIIFWLSFCIFGQPAAVLHYYVEWVKRTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Q7</accession>
    <name>A0AAD5U1Q7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exocyst complex component EXO84</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EXO84</name>
        <name evidence="9" type="ORF">HK099_003388</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Secretory vesicle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EXO84 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000222">
        <property type="protein sequence ID" value="KAJ3221573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Q7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1220">
        <property type="entry name" value="Exo84p, C-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1210">
        <property type="entry name" value="Exo84p, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033961">
        <property type="entry name" value="Exo84"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032403">
        <property type="entry name" value="Exo84_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042561">
        <property type="entry name" value="Exo84_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042560">
        <property type="entry name" value="Exo84_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426:SF12">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16528">
        <property type="entry name" value="Exo84_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25345">
        <property type="entry name" value="PH_EXO84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst component Exo84 C-terminal" evidence="8">
        <location>
            <begin position="363"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3221573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="826" mass="94605" checksum="A9014B8D28F3A9B3" modified="2024-05-29" version="1">MSSSPHVPSSQATHSDVPAIDMIKLCNDEFDVEKCQLIIIFNAIATQSEESVIRAFRTTLQGAKEEAATNLKKNVFANYQKFVIISKEIKQLESSVLTLHGLLNELKLVNANFKYLEAGGEDAESNDANATDKDEVGTKVTVDDSSVTITKQIMDAYGKHYNNIEDLVRARGLQMAQLYENVEGLTKFIPDGRGKYIARDGSNNTKIYELNPTTLKQKPQALSFFLLNDTLILVSKKKMLMSGGKNKLVADKCFLLSEIATIDVKDSESTNSFKIMKHPETYFYRFETPEEKRSFLLLLKKVSDEFMSSRKKTTCNVEEEKKSLTVKTSTVKMPFSGDNSVQNTQTEKTKKKEDSLSPQQIKFLEELPDDLEVLIAHRDFELGVILSEKAIKTFELIQIENQKHLLLRITVEEKISRLSGLIGNELARPFSTKKSVQANICLLLRLGFGEQARDIFLGTRSITIRQRIRQLKFDGNIANYICDLSEVVFRVIKNTSDWYGGSFQETFMASGFMKWVRLEIESYGSIFRKQVFESKQNFRVISKCIEFTMHHCKQLKEVGLDLSFVLDKLFFFDIGKAIDAQASLLNEVILRSFLREEFVLCAPKGEFEIIWKKDFGIMKQNPLLIFSFINFAEGTDMKFTRSVYELYKLLIDFGDDMSLVISVPLYGRVVSALKAFFATYINRMLELFENMEWKNKQYYAMMVNGNFIVDLLIPKISLQLSKIRFDRPIPELEEQRLKLKTVVLAMHGSFIRLSTVKLITKDYNFPNLDYSSSASILDVAKPSEYILNLIKELNNISVEMDPSLNKRAILQHIVERLFEIMTERML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1S4</accession>
    <name>A0AAD5U1S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004928</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000364">
        <property type="protein sequence ID" value="KAJ3218822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1S4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="274"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="303"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3218822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="335" mass="38148" checksum="8E63574DB884DD5A" modified="2024-05-29" version="1" fragment="single">MNLTQLLAPTLDGLNSAQIHNTYSISNFNKQPTWHFSHQQPTTLTQQSTFDKLSTSNEHPTADKISTLNEQSTPNKLSTFNEHSSPNKLSTLNENFNLNKFSALNDKINDKVKHLPYLNFDTFETDSFSSYSTVNSSPNQQTYNIPTNEEENQDNVDQITWSSTAVFTKSLAINNNTNTLKRKQTTEKNDIMNKNKKLNVSPSRRIKTSINTASDNFLKFFQNKELKADEFNSVEKVEVSSLTPQNLVAELKDNSNKINLPIIQEDVKSSKKFLECGSGCGRKFKSKSHLIRHERMHSGEKPYKCSHEGCNKSFSRRDNMSQHFVTHTGEKKKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1U1</accession>
    <name>A0AAD5U1U1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pseudouridine synthase RsuA/RluA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000320">
        <property type="protein sequence ID" value="KAJ3219958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1U1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="1">
        <location>
            <begin position="377"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="621" mass="72225" checksum="2AF13DC67F03B1AD" modified="2024-05-29" version="1">MYENVNELCQTLYSTNKMSILTLILENEIKEKNLRNFNYCYQRSLTTLLTKNYKLAAELFQTLVSESKTYISDIFTSFRIAESKVNFYASQSEAFDSCTVERELFSFQIQLRKPKEVDSLFEAITNFKVSVNLINEILKKNNFNYENFQQSPVTRITEGDTTSVKLNNFSNKGIVFSDVMDSHEENKIGPNREELYEHRSKHSFNLIFEKFLDFFKIVENLLNLKKVEEKGEETNDTVEFELKGKKKPTKNFLKPKQNKDLNYFEFKNKALKKSFSDATKFKSKNALSSSPKFKNPFESDIKTKPNKLNKKEENRKEHFNLKTAKKNVSTYRSGAANQKKSFNSEKNVIKNPFKILYSTEDLVAIYKKPSLALFSNYKVKTKTLYELKNPEHEIIHTLDKRCSGLLLLAKNNKGKSKLLNYFEGNKREKLHHYFTALVSQPVKNEDNHFQLVYPSFKDIRYDDENPVLEAKTQYKVLKTSSFGSLVLLKSVTNSKHQLRVHLAKVLNSPIIGDFTYGYSQPYYLSEFFHDPKETNLFLHSSRIVLKDWFDVGIDLDISAPVPEHFVRMAKKMELKEGLKKLIEEELKKPVSTDTTINETANDKAGQYIYSTPINDPALTYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1U8</accession>
    <name>A0AAD5U1U8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003201</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000213">
        <property type="protein sequence ID" value="KAJ3221712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1U8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="613"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="253"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="406"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="976" mass="113497" checksum="E6B3A27293E07216" modified="2024-05-29" version="1">MTGFDYALDLETYLTNYIFYALLAYVFLYFLPNFFLKQRIQAVLQTFFFAQVPFSLPYLIRTYNLLEIGKMDISEFKDFMYFCSVSGIVPVLLLSRCIFKDNPRRTFSLLVFTFIPIRLAVSIDFLPNRFKSGDFTKEKQVLWCLILWRCCWAYHFTGRFFVTIYQLIVGLIRWHRNWKTKADSDDSFRESLREYLGGRKDKIDDLQQEIYQLMMKNTAMESDHTNELLKYKLVHERLISKATAAFKDKNLQIVHFKHQNNNIKEKAQELEKELECVKEELRVLRNAVEEDGDVKEKFLHQRSLNEILRENTTSLEQNLAFLQKKIKVEQAKETEMITKMSNIEKDFLKAMNVGNELTIILKARDEELEMKEQLITNITLENEKKSKKIVELEEFIKLEAEREACVAKEYRTADISEKEVESLQEKIEMLSTEIKITKLELGNAIVEKLTTGNELREQKYLCSMYTEIIRDKGGVGEDFDYKKALIELKTEDECENISLDDKTFEFFQIGLNETTAELATGFPCPTKIHNEVNLPIKLEIPENVSLISVGGIHILYADEERKTVYQYGEEYAENDNENGRFLKCWSVDDDEPEEYIMKLEAMGAVSIVLTSLGRVYAWGGLKDDQAGYVQLNIDNKPINLSSSRAAIDVAASESQILVLMDDGSYMVFGIIAGTGELELLKEVHSGEEMRHCWSGENNLALINDKGECFVWGNNYAKFSDDSTIEEMEFLFDPIKLNLPGERVNKITFEKYTCLVKTEAGNCYVYGTNHFTNLDIFPLNKVHDIASGHGFSAILTEENQIIYSGLAEFVDSKFDYDIPLTKYIQDVGFIPTAYTIEDKKYKIVGSNSQFGTILRLHANSQYFIVQCQSKTEERFMYDEEREEREFVTTKHDYTDEVTFTEVKYDDLLVLERRTVLKRCNQLRVVEKLENRNIDITDTIIRILDSLPEHVLDNIGAPAMDLQDEQRDDRDFQFYFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Z2</accession>
    <name>A0AAD5U1Z2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000307">
        <property type="protein sequence ID" value="KAJ3220318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Z2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="396"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="476" mass="51414" checksum="23513969ABDC92B1" modified="2024-05-29" version="1" fragment="single">MNTLLISRPTLSFMRAPLSTQLGQNFRYYDPDFEQKQPSSGSTNGSVINSLKVGAGSSGYYGNTYHNFEVPKYVNSLVMNTDNSKKGFSVSDGFKRDSPNSPQTVTVTDFDAWFNQYLGNVEAFSNWVKAVSGCNDSNFLATNVRYIKSSMCALLVLAEPPCNSETVPNICSSTLSVFSNQFSTDFGLPDNSSQIDPAKCNQVNSDTNLLRSFKEMVNTQPSSNCIPGTEEEVLQCGFSDLNLAKAYCAEVNPADNCCNSQRIGFTAVTDPLKLLPGENLLQPSATLSSSNLNPTAQASKSPTVSGSAVPISSSNPVQGGVVADNMWTTPVIIGVSFACFVALLAIVLTTVLLTRQKKTQSFGKTIGETPIPYKNNSNDVDASSQSTLNADKNAISVAETMQAIYNYVPNLSDEIYLYIGDPIIVKNSFDDGWALGYNMTTKMEGSFPLACVGPFNEGQRGNGEASWIDRNSSLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U252</accession>
    <name>A0AAD5U252_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribophorin II</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Ribophorin-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_005736</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SWP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000460">
        <property type="protein sequence ID" value="KAJ3216801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U252"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055374">
        <property type="entry name" value="Ribophorin_II_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056790">
        <property type="entry name" value="Ribophorin_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008814">
        <property type="entry name" value="Swp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640">
        <property type="entry name" value="RIBOPHORIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23860">
        <property type="entry name" value="Ribophorin_II_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25147">
        <property type="entry name" value="Ribophorin_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5044286216" description="Ribophorin II" evidence="13">
        <location>
            <begin position="21"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II third" evidence="14">
        <location>
            <begin position="35"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II C-terminal" evidence="15">
        <location>
            <begin position="178"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF25147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3216801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="288" mass="32784" checksum="4ABB3703702EF4FC" modified="2024-05-29" version="1">MRSVLSIFVFFCIVTSEVQNFSLSDINFALGPINAEKLKFPNKLQKPLEVSQAERLKIKFSVESETLKEKLNPQQVFLSLEAEKKNSHGKLTLVFQREEKKKGDYSLIIDLKSKNFVEALEGEAGNYLATIFISEPNYSPLSYSLGTFIFKFGEVPNINRPASESEEFRYKEEIRHIFKPPVKVPFRLISLIFAVLCVLPWVILFALWSSLAVNFNNLYATKEMVLYGTGFMISMGGWVALYIAYFWSVTLFPALACASVLSVFSLFFGNRVLVSKVQFSKLKTQKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2E9</accession>
    <name>A0AAD5U2E9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000561">
        <property type="protein sequence ID" value="KAJ3215193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2E9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="538" mass="62676" checksum="6041DD47001B8CA5" modified="2024-05-29" version="1">MVCRECIQDNHVEQLLNLTETSQQNNLTVEQELEQLNPYPELPHPIVYKLKTCCLEEFIPYNIFENNKISNFFNHPKFNPCFRTRKLELPSSGVAYLLRGKKYLLIETVDNPASKYQTQEKFEILGLGVKVEENLISNPSENLVAEISTAQQIFEETNQNITNAAPIKNISKRETGLYELERVDLRDLSEVPNSLTEFLFCFNLHADGDKPCQREDDEGYEYADDEFEEFEEEPETYSELYEGISEVLNNPKNSSENLVNGVEEQELFEDMFKKFKEEEASIITKEEQDLMKHKTEKILETEDREVNKTSNSNEKKKSNLKLNTRTPCECQLIRLKQKLHRDLFLYLVLKYLKFIKNFVKIERQQQQTNQRKPVNINSNVGINIETDYENCLATTKINDEFCDNLDSAIDNSSFFSSPFEIDAGVEQHALNNEKKCINLTQIDGPEYREDEGFLQNYPSILQDTALSNANLTNFYEFEIEEFNSEKFEKSDNQSFILNSEEEKSIANMVENLSEVAAQEILSELKDMYLALKYYQKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U312</accession>
    <name>A0AAD5U312_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial proton/calcium exchanger protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Leucine zipper-EF-hand-containing transmembrane protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">HK099_001960</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LETM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000161">
        <property type="protein sequence ID" value="KAJ3222745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059005">
        <property type="entry name" value="LETM1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26561">
        <property type="entry name" value="LETM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="16 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15 18" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="837"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="23">
        <location>
            <begin position="883"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="22">
        <location>
            <begin position="1289"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="728"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1321"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="1100"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="1197"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="732"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="768"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="1331"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1344"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="1366"/>
            <end position="1376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAJ3222745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1376" mass="156680" checksum="BB864DEECA6124A8" modified="2024-05-29" version="1">MIKQLKKGISNSSISSNASLSLTYSALDCDFKFTLTDWIIVFEPDTKDKQSSIQSFDLLIHRLLNSGLHLKTRKFTETALAIYIHCPKPILAREAYKNQVEDWLNNVGEHIEPPVFLTDENIDEIVGYLKPAEKLRVIYDLLTTPTYKGGIGLQVGVNCKDIFASQDLEFNKSWISSWNKKFLLSDGDLSLIRDYLGERTAYYFAFLQYYFLSLSVPTVLGLLVEKYSILYGCFMILYAVIFVILWTRREKIWAIKWRTRNLNNADKLHPEFKHTKLDVDPITNEISPYYPSWRRIAKIVFISSPVLIISALFISFFVLVNLSIEVFVHEYYKGPFKAIAPLIPTICYSASIPTFNAFYSKMMIKLNLFENRPTEREYHASLTQKTFLVLSLVGFLNLFLVGFGFIPFHDLVQKWLSEHGLISSASSIREIGPHIFTERLVYFVVTGQIVNAFTELGLPFLRGNAEKYISKENLVELTEEDARLDKEEIDFLKRVRKEFEMPEYDDFNDYVEMITQFGYLVLFSVAWPPTALACFINNFLELRSDAIKIAKYTRRPIPTRSESIGPWKNNIHLICWLSTFSVTSLIILFRDWDSSIPSSEQTLNKMGRLTFFLILNEKIFFAVKKTLTFLIDMVPIKGEAGLYMGMGELNGDVRWHGSVEDEGKIVMQGVSLKEIHNLLSSIEKKKKNDEKYKPSSSLSNLLFLKNFPLNNSNSQLNKSALLHFSTLNNQDHNSDKRPQSKTNQKEESVVEKTIRTLKENTEQELPVSPNTSQQVSAQPPKPPLLQRIKAEVLHFWDGLKLLAAETGISSRLLLKLGRGNKLSRREMNQLRRSMGDLLKLVPFIIIVLIPFMEFALPLLIKVFPNMLPSTFESKYQEEEKKKKLLKIRLEVAKFLQDTVGEMAVAGQSKTHNAKEFVDFFHNYRASGEQAPTEEIIKIAKKFEDRLTLNSLSRPQLISMCRYMNINAFGTDPYLRQLIVNRLDELKADDQLILSEGVDNLTVQELQTACQARGIRVIGASPARLRSDLHQWIELNLNQKIPSSLLILSRAFIISERIPTDNEEALKVSAQSLQATLSSLPDQVVNEAALKVAESEGSATYKQKLDVLKEQEELLDDELEQEAVQAAIKKAKETEAERLEKEKEATKVPMEPESAGVYYSATEPEIEFPEDKINEEDLKKEIKKIAEVLKTTTSDSALSDVKAKLDSLKEDRKGLTEGLEELQGLNHQPTSKSTQRLSTKLDKMISKIEQELLKYDSEIGSKLHLLKPNEEGKLSITELEDCLKVIRQNPNDERIKKIVKNLDFDGDGYVTLDEIRNLVEDEEKNEGSGVNLDKDGNKKENTVASPTSSTTSSSGAQPVHVIVEGSKASESKPESKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U359</accession>
    <name>A0AAD5U359_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EF-hand calcium-binding domain-containing protein 4B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">EFCAB4B</name>
        <name evidence="4" type="ORF">HK099_001818</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000156">
        <property type="protein sequence ID" value="KAJ3222854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U359"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="431" mass="49103" checksum="E6429C67F1C10652" modified="2024-05-29" version="1">MAASSNESIISWNSDLQLDFEDNEDPNSELSTNFQGLQKPSNEGDELYNIDCNVDLSFTIAVVGADESGKRSFLRKVCGEENVSKVDIRRKQIIFKSKVLIVNDLVCKVNFWCAPGDENWRSRSCKLLSNVAGVIALFDVTEKYSLISAKTWLEELDKNRHFGNHKRDFICKKEEKKKRDRPPTFLVGNKTDLNAFRRVHYSDGSDAAYGFSVEYYEVTCQNLPKVKEDVEEELLQEEEKYINDLLKKSDSQYEATNLESNERSENPKSLPQAPVNNINESSVTDRNYQACLNILSVPPDLLLSLHINVHRPLYISLPSNFEPFEKQLEKTENLEKQKTELPEIVNQALSHFGDDGDGILMVGKNGNFIFCADGISEVINDSNNTDAINKTVEIISQGENEVNYFSRLRYNAALDRRHPKHEVASQKVDWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U398</accession>
    <name>A0AAD5U398_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001984</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000162">
        <property type="protein sequence ID" value="KAJ3222718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050384">
        <property type="entry name" value="Endophilin_SH3RF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="5">
        <location>
            <begin position="13"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="389"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="231"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="287"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1435" mass="163002" checksum="5FA82E7B33855FC2" modified="2024-05-29" version="1">MSKAFGKFKQWTGEKTGSANKTEASEDFKRLEQETEYRKECTEKINEACTMYIQTLGKKKDSLGSKVKKLPLEVLSDSMISYGKMLNDESYYGKALVEFGAATENLSQSQMEYVGKIRDGYAASIAHCLVEIKDYTTLKKKMESRRLDFDAKLNKVQKSKISKPELEEECRVSQMKYEDSLSDVTNKMLSLNSTEDESLDDLLSFVDAQVDYYVQCTEIVRALQDKLRNFPKQGFNRDRNKIRSTSPKRINSYASESARGVSAERSNLQFDSSGRNRVGSTSSNDYNRGRNDYKRDDPNEERKYNDPRDSRSVNDPRDRRVDNDPRESYRKNNEEDNDFNRTRSSSVSNEKLRYATEQGNMVFPIGGSNLIKSTSNSSSISQLPAGSKNSIKQVKVLYDFSADGPDELTIRKGEEFTVVAEIDAGWWEGEYSDGRKGMFPSNYVQVISTGPKMPVRPPVPSATSGSINQDYVNRSRTGSFTNSLNNSANNSSSGGRFNASPQPMQEKINNNCTVCDCDEYKPNAFKAGQSILFDATETERDILLLYHYAFIFKSSEGEILDEMVVQGSLQPIASKSFPTAGINSVTFLVSSQLFNVSDINEWSENILSKITRRFEIFASSECFHYVFNTTWNSDNEVLIYSWVSSTLKFLGDISETLTKSFQMLGDYPNATLRNSTHSFLFEFDSLEQYNTICFDLNTYECNNLYIIDIDFVNTVNWVVLTNYGVYLFDTSFLKFSSSKLNGLEFTNLSQYSKIYVFKDCLSNRDSSIFFAVADNEDDILNKLIFYNFLKDTEEFISGSDIGLKANEEIVSLEFDFFKDNLIILVGTLKEVINIEGKWTKNFQNCRIILLNLYTRVKTIGFQFPISSQILHMKKHLNFLELVIVGDKIWLSLDGGVNFRALFFALPGEVFFDFESSATGLQLFRSNFTRILYGKSGSTEFFTIPFYFNKNKQNFHCIQLEDDDVVSILIFKDELTNEEDVFKKYYISISSFINIIDNSFGSTLIPTIISETQMYFDVFNSSKITFKSSDYNWAIGQNFIGGGSAVVKKIFDSGVKLKSVVEESLVPETTKKSPCLNYNLDLVDLKKIGELSWNMVGLLLSKSPTSEGFLLSDVGKTVTVNGGSILIKSLMNNSYANGYIYAYPVSDIQASSGEWFMYDFRDYTEFGESFSQSLIIEESSGNAYKFLFSVTIETGFMKFTDILIGKILSTDIGWGRIVFVESESVMLITNYSIITNGTVPRSSWSIFKESETVTTFNTIPSVENRIRPWSLKLRNCDTHLILSEEENNRDAIYFPYLSTLRINGSVLTSKFNSQKSKIVSKISFLTNNRHLYKYAKFVTTPNLYNSQLEMNITDLGKKGQSILSLRPSPLSLKCKNGQKIFRTIYTSCASYSQSPTKTKMFRLEGGNVLHNVSMVDFSNIEGITYYIVKNRELLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3D7</accession>
    <name>A0AAD5U3D7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin-conjugating enzyme E2 U</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UBE2U</name>
        <name evidence="5" type="ORF">HK099_001555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000145">
        <property type="protein sequence ID" value="KAJ3223074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3D7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="418" mass="47737" checksum="BD31239FF9047FB8" modified="2024-05-29" version="1">MSLQPRTALLLQKELYKIEKSIMPVGPIETPWEGGIFSVELLFSQNYDEIPPEVIFTSVPFHPNIDVYTGKPCLDYLDDPYLWQPEFSITSLLLQLQFLLSNPILLNPINAVAADVCLNSPRLYEQLIKDSVVASRRIHAGLPVFEKTWEEKPAISKKVALSLPNSASTSGAKKLAGENLTLENNKNKIKTTKTSFENYYQNWKNLATSIPTSNNKPLVLSHIITKPKKLFCFGNEPLDEVEMQEILQKQHHLYFGKFPYINNTELVKRTSVKLTNMKRDLAMFSKLEVQLDQVKQLTITDNSQEQIHTDIEKEKEVETNIAIKIPMNATQKENQDFEENKFVTDLTVDRFEKLVSDAVDDHFKSNTSKKEDNLIEPSSTAPTNEKQVLNDLDIHLDGEMEDLVEWSSKLNETNIINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3M2</accession>
    <name>A0AAD5U3M2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUS-like FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000133">
        <property type="protein sequence ID" value="KAJ3223361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3M2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052582">
        <property type="entry name" value="tRNA-DUS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="1">
        <location>
            <begin position="9"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="37567" checksum="727559773B9CF093" modified="2024-05-29" version="1">MNHQTTQLMLAPMVRISSLPFRLLAAKYGAHQVYSPEIVDKRLIATTRVINKNLNTIDFLDPSNSLCLRIHVNEKLNSKLVLQLGTACPELALQAALKVKDDVYGIDINCGCPKKFSIHAGMILKKLVDNLNIPITCKIRLLGEKEVDISATIDLLKQIEQTGVSAVAVHCRTREERPRDRAHVDVFKQLVKAIKIPLIANGDIFDFDTYLKLKSYGVDNFMLARAAQDNPSVFKLLTNQINDGVSHYTINDVFEVCKEYLKIAIEFDNPTANTKYCILQMVQPKLGEVKKKVTFLRRETVGGNRGVPKSTRIIELQLPIKDAVAQAKTMQELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U492</accession>
    <name>A0AAD5U492_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000385</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000109">
        <property type="protein sequence ID" value="KAJ3224008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U492"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="565"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="666" mass="75373" checksum="10A305B3ADE32B56" modified="2024-05-29" version="1">MSEYQKLNIEENDQIENDLDLVFDTEEHFLLRNLKTSDESDEVESEDTEAFAFGEEEKLPASVAAVVSEFDEDLPCLTFPSAAQFFFFRLVGLILTPYIIQMISFPLGKFMERVIPEGKFNPGKFNVKEHVLICVSASTASAAAYGIDILTVQRIYYNQNIGIVPSLILLITTQCIGYGLAGFLQDFLVKPAKMIWPIVLSTVAVYNTLHEVTTERGVPFPNGSDKNSILEFEEKIYTKNISSIGPSYVDGIELFPIFNSSYVLFDNLTLNEARYKEHGPLLLSPWWSYGYGALFATLTATISWVYLFHGSEILKILKNLLKNKALKRNLNSDIHCRLMKKYDKVPKWWYLSLFFFMLFLSIFNVEILAPELQIRWWGICLGVLISSFFALPVGIIKAITGTGIGLNVLTEMIMGYIKPGEPISNICFKTYGYMTMSQGLSLVEDGKLGHYMKIPPKKLFLAQLFGTIIGSITNLLVMELILKEVDFKNPNGDPQWSARKTATFYQASLIWGAVGPAKLFGGYYKNRLLFFLIGLVLPVIIYLLHRKYPKSYWKYVNIPLILHATTLNISGAHMMLSSILIAISAHLYVKRNFNELYSKYIYVLGAGLDTGKVDRNQSSLTSISKGTTISVVICFLIFKVQNVKFWNWFLNPADGPTDYCYNSVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4E6</accession>
    <name>A0AAD5U4E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DERL2</name>
        <name evidence="8" type="ORF">HK099_000524</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000112">
        <property type="protein sequence ID" value="KAJ3223928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4E6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="26625" checksum="9B751084B77D45A6" modified="2024-05-29" version="1">MLEEGSFRGRTLDFLWMLLLGATSMVLIVPLINSRVHIPFLSSPLTFMLVYIWSRRNPYIKMNFLGLFTFTAPYLPWVLLGFTVLLNNFFPAGDLLGMAVAHVYYFFEDVYPRMDGSNGWRLFQTPKIFKYLLEDIWSSRDPSIADLPANMNNLDNEIVMEDINHPDISLAQDEVPNPNVAVDEKEVVIESNVEVKVTSEFKNAENVSSQIGAESSIRQRHIKEEDLKENLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4P6</accession>
    <name>A0AAD5U4P6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000102">
        <property type="protein sequence ID" value="KAJ3224161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4P6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039720">
        <property type="entry name" value="TMEM94"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13219">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13219:SF6">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="370" mass="41751" checksum="4D667075F298BAED" modified="2024-05-29" version="1">MSGKTTTGLTKDEAFNSILLFLIAIWNVILFVREARLTQLEVVTRIETVIENLRESKSLTVREYIKIPDTLPTVAVAHVLRDEQIYTVPLSMLVESDILLMTFGEASPYRLVNVPPPGVEINPELPEFILEKNEVLSQNLQRSFPYGESQGKMYFKLLETPLLFSLKAALDKKRPETVIVWRLRKLNRLLVTRVIWVLLGTSLVINLIRFFLEIATNDYQLNQQSKTLVVVMQLLLNMQANSHSSLGLPTMLLIARSYGNAQIICLLEELQNSTNAHFEDKDDIDEFDPAPPPTLQIATSWGILLPSLVLTPTEGPIAKKFWDQLIRFDVDFLARTTGLIESLADTTVICSIDREGTLSKVGCSLCNCFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Z6</accession>
    <name>A0AAD5U4Z6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WW domain-binding protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">WBP11</name>
        <name evidence="3" type="ORF">HK099_003483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000228">
        <property type="protein sequence ID" value="KAJ3221473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4Z6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019007">
        <property type="entry name" value="Wbp11/ELF5/Saf1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12622">
        <property type="entry name" value="NpwBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09429">
        <property type="entry name" value="Wbp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wbp11/ELF5/Saf1 N-terminal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="351" mass="39493" checksum="B326FA5DBE1C443B" modified="2024-05-29" version="1">MAKTALDKHRQQLKKKEKKKQKEEKERVRTLISANKDLTQLENEIQVYQNLDKKGKLDKNGKIKLSKLESDLVKVKRAKEAMGISTVPDKIPLVNTSIPNDPKKSIYFHPIFNPYGVPPPGEAYKEIDDEKKKNEAESESESESESESESDNLSNSTSESEAVESTKKKRKFEVKYENLSHIKLPKSEAPDVEANIFHSLENLQEIRHRPPAQNTQRPQFQHIFVPPQQHQQQANPPHGLPPPPFGMPIPHFGVPPYSGGRQPSAPNFVSYQPGEALAPKPKIEATNAIISALPQVRDLKKEVVQFVPAALLKKKADNTAKVIQPIKKKRIVVNAAPKTEDDVLDSFLKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U510</accession>
    <name>A0AAD5U510_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Ubiquitin-related modifier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">URM1</name>
        <name evidence="7" type="ORF">HK099_007938</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the URM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000082">
        <property type="protein sequence ID" value="KAJ3224753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U510"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01764">
        <property type="entry name" value="Ubl_Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03048">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015221">
        <property type="entry name" value="Urm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14986">
        <property type="entry name" value="RURM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09138">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037379">
        <property type="entry name" value="Ubiquitin-related_modifier_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="modified residue" description="1-thioglycine" evidence="5">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="93" mass="10614" checksum="F29E467EF2D967AD" modified="2024-05-29" version="1">MKINLEFSGGLELLFDGLKQTSVVVEDSSLKNLFKKIESELITQNKELFLKDEKLRPGILVLINESDWELEGQYDYQLKDEDTIVLISTLHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5A3</accession>
    <name>A0AAD5U5A3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000293">
        <property type="protein sequence ID" value="KAJ3220530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5A3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033553">
        <property type="term" value="C:rDNA heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070824">
        <property type="term" value="C:SHREC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038986">
        <property type="entry name" value="Clr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031915">
        <property type="entry name" value="Clr2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38046">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38046:SF1">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16761">
        <property type="entry name" value="Clr2_transil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="3">
        <location>
            <begin position="746"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1264" mass="145537" checksum="C8E2123DCD1211EE" modified="2024-05-29" version="1" fragment="single">MLIKSDGEKSLIPECNALILEPTEEVMNEWLFNLTKIFLLYQNEKKQNNNFKAVDYNFNKILTLFEDGSQQINNLSSETHRITSFPTNYKLLAVKTSTEEIEYYVYGHPACIAKQYRFESFFSFAIHFVWLLRYTDGLTNDHFDCSCIGCKKLIELNKIVHFEQRGAKLINYNNELSFSNKLTYAKFRRGELVWLPLSGHSPDNLTICCDYLSYLKYMKTSEISNRVYVNLSTIMFWPGIVCGRLLYRANVTENATMVYTVMLLGLYSEFTLDQSQIFPFKRYSPCKMEKGKKKFHLKVTLELKESYFKAIEIAKQISFTLSPLYPGISKKGKECDSNLNETKVAEKVVYYKCLLLGPEVISGGDYVRIVNKANTFVGDLEVLKVNKIFSISSDTGNNYYFSGPLLKENSNFSCTIIVNNHDPFFFTENENSNFLLNRRYPAWHFQSLANVFNSPNDDILASTTVSINNVFGRFYYDERDVTIKSYAENPKEYTEVSISKKLILDNSRINIEIDDSDLFSCEYKTKDDQTLYKNLSTATKNFIQVDGVSSYTTVEKRKYLSEDYHQNKKIKHAFECQPAEILSNEHSPLTDNTVGLQLSSSDIRISPCLHNESELDANDNTSIKSQQCKKGCIAVTKHKELYAKSARERQCTFSRSKVIEKIDNILEIEPIPSCLNKVGCLVTEIGVHSNKENCETAAENKENTPFLSKEEEDAVFRRCSHILDMHISDLDAELRTKLKALFLQLLSKKDSNIYQRPVSHIDAPDSIQNVKNPLDLLQIGVKLDLALQLKTEQKYTPEFNLKAYGKLREFLDDMENVFLNSSYQEIGDGASIRGKSIHVIFKICFFKFLDYCLKYYPRCSAPQNETVCENNLKEEKVFFVKKNASVKDTFSNECLGIQRKDTTRENEHILQKVDTTSITVNTPDVQNKSYKKCEINTNQKEISKFSYLSQNIPIVEVFIDENKHFHNVNDFFVKVSKFQLTDTIENDIINKLMVNYDFDLPDVLFEKSLKALNEKCTESKFQLDSNVDEVLKLLQENTNLENTNLEKTNTNKVECKKPVSIISNISSHKNSTDVKEKFDVEKSNVNTVVENIRCENSNSTIKIAAETAIKKTELSLPKKSEGVVMGNPPGSKKEGIMNLLDIEYTTSNGELKNVCFNGRGGIMCKDAIHLWKKSCPYLPKLKNLPKLKILQLFDQKVVNFQNRNDLIFNDEEFVTKKQAKNLEYMESLCKKYERDAKKVFILISLFFNKESLEFQLFKNFIGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U617</accession>
    <name>A0AAD5U617_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006346</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U617"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="203" mass="22876" checksum="03286B407E002DB5" modified="2024-05-29" version="1">MEEIVRAFNHVINTGKAFYWGTSEWSAEQITDAHRVAEKLHLVGPLMEQPQYNMLHRERFEKEYAPLYKKYGLGTTIWSPLATGILTGKYNDGIPPDSRLASDSAFIKNIGLKAFQREGQVKIEKVKKLKPIADKLGCSLAQLALAWCVKNPNVSSVITGASKPEQVLENVKCLKYVDLLTLEIMNEIDEALDNKPTPEVDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6P5</accession>
    <name>A0AAD5U6P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002835</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000198">
        <property type="protein sequence ID" value="KAJ3221972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF53">
        <property type="entry name" value="TMEM14 PROTEIN HOMOLOG YJR085C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="115" mass="12575" checksum="9DBB74E6C4BD54D1" modified="2024-05-29" version="1">MSHYLAFTMAGALTAGGVMGYQKKKSTSSLISGLFFGGLYAYSGFYILRNRPYGLDLALTTSLFLVMIFVPKARKTRQLQHAVIGALGLFSVYHFGSAFHLGSRDLLTLIKNKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U738</accession>
    <name>A0AAD5U738_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_003627</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3227004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U738"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031647">
        <property type="term" value="P:regulation of protein stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000005">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024729">
        <property type="entry name" value="USP7_ICP0-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029346">
        <property type="entry name" value="USP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF644">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14533">
        <property type="entry name" value="USP7_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12436">
        <property type="entry name" value="USP7_ICP0_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="MATH" evidence="10">
        <location>
            <begin position="42"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="11">
        <location>
            <begin position="214"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3227004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1132" mass="130694" checksum="68E5423AF6AACB4C" modified="2024-05-29" version="1">MNDKSDDTMELEFTSDNTVGDDTNELIEKALPTDSHYKVEDKVRYVWRIDNWESLRTREKVHSPVFTCGRYQWRILLFPNGGNSPEYISAFVESVEASQEKEPVIKFHIFEISNFIKGWHVCAYFAICCENYENNEIASKINIAHHRFTSGIIDWGFKTLLQVAQLTQLNEHKRSLLEKNRINLVVYLKIIKDETGVLWHNFMDYDSKKETGYVGLRNQGATCYMNSLLQSLYFTNYFRKATFEIPTDDDEPTKNVALAMQRVFYNLQCADNAVSTTELTKSFGWDTLDSFMQHDVQEFNRVLQDKLESSMKGTAAEGAISKLFVGKMKSYVKCIDVDFESSRTEDFYDIQLNVKGCKNLEESFVDYCAVETLEGDNRYMAEGYGLQKARKGVIFKSFPPVLHLQLKRFEYDMQQDAMVKINDRHEFPNEINLDKFLEVEEESETESRLPQTYTLVGVLVHSGDLHGGHYCAFIKPEINKNWFKFDDDKVVPVTEKDVFDDNFGGDSAKGPKLLKRFTNAYMLVYVRNSDISYVLAPLGEKDIPSHLKKRLAREAEDNLAKKKELEEAQFYMTCRLFSDLDLKNYGGFDLGNFDLHDGIRSVGIEMTPSKIVKVKKSDTLLDFKHFISESFKIDIAQFRLWLMIGRQNKTIRPDGPLLEADNKLSMEAIKDKLPKHANISELKIYVELPDVEVTSSPWFLSRENPAKQECIIIFLKYYDPYLQKLEYIGKYTVPNKVTNKISSLVPIVSSRLKHPEGTTYVVYEEIKPTMIDMVTQHKTFVQAELSDGDILVFQKSLSKQEIEELPDKSMEKVTNYFDSLLNRVHIKLREKPTDSSPFKSTDKGLNDIDLILSKKTLYDDFAKAAAEKLNCDPMKIMFSMSNNMSAAKGMIKRNEKLTLNEMIPGLGHYPNNTNLVFYELLNMSITEFDLKRLVKVIFVDSSFKEQGPFELLITKNSTFADVRDAVLPKIKFEKTTGNFRIFHYQQNRLGRQYQLSDSLATLSENHGLYMDQESLEEEEANRKSSEIVVPVAHFSKDISRTHGTPFLFILKKNEIFEDTRMRLQSVLSMGEKEFGRVKVAHLQRHGTAARYFKDGDVMFDHFRDHDYIGLDHPDKTGKSSRIGNMEKALKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U747</accession>
    <name>A0AAD5U747_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000063">
        <property type="protein sequence ID" value="KAJ3225385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U747"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="100" mass="11687" checksum="56FF4E312F65715C" modified="2024-05-29" version="1">MTETSTELTSIKSEEVSTRLLENRLDHLERVSFKKKKENQKLNEYEKNNQNFLKNSHLKDEIEQKVDGNKKKDGFDLDVNVKTELILSSEDDLISFAEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7E2</accession>
    <name>A0AAD5U7E2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7E2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46613">
        <property type="entry name" value="RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46613:SF1">
        <property type="entry name" value="RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="877" mass="102642" checksum="3DA752A69487A63A" modified="2024-05-29" version="1">MAAVEISPNAEQLISNNSTDVDNSIDNVQHLLQLPVPLNINKNDCDCIMNFNKLTETGTYEGDGNGVGHYRWFDGVSFMGNFKDNRMEGFGEYNWPESTFYKGEVKNGLRHGSGEFFCKDIASGYIGEWEEGLPHGFGKMTYDGQGLSYYEGNWLKGLKEGFGLMVYKSKNSYKGYWHQNLKQGTGLMIWEDLKESYDGEWMNGKPNGTGTHIWYIENSKHDIKPHQFPTNNAYRGGWKNGKRDGNSEENILSGYGEFFYASGAKYKGNWKDNMKNGFGVYLAEDGRRYEGYFENDRMTDEFLKFLNETPHYFKMDKLMCHYNQMDKFSFLAESNSDTVMESNTTVNTELYSKNLEHLKSLNNVFLCYNSKLIEIYKYYCEKRQKTNLSTNFMKNTFGLISRIEVWDFLKVLTKHGLSDASRIEIDRFWAMKFKNDNQYRKTRFDFPHDVNETFNYQDFLDFLLTLSIFEKKEITKKFQNKIKKKENANLKNKNTSNYEDSSKKNNFSANFTVNINAALQQQPPRFSVKSNNIVNSYSKGVHHSTSPNCNNGNAYNILKKQNFNLVLSDYLKSEIFWEEEKKLINFASSFENIKDENFKNIGGNEYSNNEDVNEQINAYERNLYQEFQRKFGDRIYKLYFQRACKREHSLEGSIGDVTMTLRDIIYMLDDFKLFDSDVTGLTINKVLSFFSQDRERISDGSFYWVEYEMVPLTLFESIFEFSKIKNNFKKLIWDKFLNDKLKKQKNDEFCLELEIKEKWNTTDTESANMEHITSDSPLTNADVLENSKIDIDDKSAMREPEQTKALENIEVKAEENLNIKFENLSIDNNFVENSKTECKQDSPVKEENLNIETLEEPFEECLLKMHDFFENLLKKQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U800</accession>
    <name>A0AAD5U800_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COG5</name>
        <name evidence="8" type="ORF">HK099_001466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000141">
        <property type="protein sequence ID" value="KAJ3223164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="7">
        <location>
            <begin position="831"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1864"/>
            <end position="1939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2106"/>
            <end position="2131"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1256"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1796"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1909"/>
            <end position="1939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="2108"/>
            <end position="2117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2120"/>
            <end position="2131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2131" mass="245497" checksum="107DB880D8994DCB" modified="2024-05-29" version="1">MLSQEERAFYESQDYKEFTKESFDPNDYANTQLSLEGNLDISTALSKLSFNIEFLNKLIYKEVSENYELLISTVTDLKEIEIILNLIKENKLLINETFERLKLKIREPTELIQRKIISLERVQLCSEYFRTLIKFFQLLKKLKQEWGKDIEENLNQEKLVEITGSGGSGNIKNGFKNKEILKAAQTLADIEFILSKNNLNGIKSVDSETQYITNTRNEILMESEVIFQQGLLTQNQMDIYESLCILFSLKELSNKCRQIITSVVSDITENLKFTFDIISINKEISTATVNSSSTGGVKRVNDSANSNQLFQKYFWSRMEKFFDSIFNNASQVYVLERVLERNFDTTKLFAELNMANDSSLTKQFWNNFSQVFDQELKASVKGSQLLQQILQNGYAKMLRMVKELFGRLEMANAEKNLELQDINKEIPPQTAMLKPLASFELVYIKNSLQRLLEPVNLAFPKDRVGGKGSIPTRDEVDKITRVISSELEVAKFDAILLKKISQNVVKALTTFSVKAENMAIDEVLQSVVEPMFFQMAKEFESTLLKIHKEDFSKPKSTKLAQEATITSPYCFEFSTKLRWCQREILAKLQCGDDSKDWPLLFMELNILSEEFLTAKQKQELNLPPIIVLQNMFTKSYPKLLPPLKSRFNSNVEEMNDYFDKNLSTVKISNILTLYVNSLESYSNDIKSKGEKEFCPEFILIRNCVQKLKQVIETGFIGEVLVCEMEVPAPTSYFFDTIDNQDIALNESLHSGRVLSTTSTFLDIPLKRNSLIPPNLASNKEKFNILTKSITSKITNSIININNNQENSGTQNNQNVTDINSKGEYYLDFKKILSPLILNKEDFDLGAKFGLESEKGKKYNNSNNINYPTDEQWYQLNQLRIHAGAPERSEEGIERLLNYYAQLIKIEKVFPFDTFQVETSFTWQDSLFPEKKVTCNCIQYEKASVLYNAASIYSSMGKIQQFRTIDGKKKSAMYFQKSANLLLYCRDSLIQRFKVKFVHNDHRDLSENTLTALAEVMYGQAVECYFEKANEDKSSSLIISMISIQTADHYETALQIALGVINSSTSSFQNKEKLPKNWMTTLKAKSSLFNSIAHYHCPGSMTADKALGERISRLTLAKSFCTKSLSFSLSISLQQICQAYFDLISNALSICQTANFEKHHQTEIDCRLLQPPRHPQQSILQFCSTDNLLGDLNRFENIFVRVKGKELNEFSISYIQEELKRILQEFQKMFEMGQNELKSLFFLMESENILNSSYVANASLKENAGKTREEMAEEIKNYRLDIHKKSLELIAQIEELKRNEEILSNEKIFKIFDDVSKETGENLTQEQMTDILPSVDVSYTFVNDQDLEMEVQKIMQEREFIYHKLDELKRKLSVHLNEFGKSNSTSVDMSSSEELKKLLDQKKSQLDYNEDTISLIKKEKIMLIQKLEEVKKAEKNQQLKKIKDQEYQKIIQLFTCNAKDYEKFRSDIQFFLKKAVQLHEDSSSFLRYCKTLDKNECDFIASIDDEKESEPVSAEGESVSEFDPLVARFNQFKSSGFYKDKPKTDNSETLTTKETIEYLIETKILKPEELDCMLRENSHVVNEETVSNILYKEKKYKEIIEQQIKMDLAYYEQNEQFNNINDSFLQNLNFLSTSQIGKNQLQSNESSVTNNGMTNAEISNSISELPNTKISPPKRKPVSKPINMKIPISTQNRTLSENIALGADKWKGIVKMVSSAFQKSPTISRNTSYSSCVEGNGVNDAAVQTALHFQQSFNQNLQIKNEEDNLKKSSSTVCQRNSSITIDVDGDSNNNSDFLINNIKLQQLQQQQLDLQQKKEELQKKQLKYQQKKLQDSINGFFKVREKQEKLRESNAKIRELEKFKAYQSQKLAQSNHENKRRGKELENQSKFKPLTEWVSEQTVRSEEKIRETPSASNSQDFQPTKPNKQRVVKNSSSKNNYTIKSTTNLNNFMKTEDKIKERKNFVKSSYPGINIIFENEESKKPTSGGIDSNSDYRGIYEKYCRENNNQHVHIHFSQTKVDDTNNEVIGDILEQNYNSSYSTRKPVNYNANITREKNIESQFRNILERGDSGLGSEKKKSFAKSGNYSAEVISVREVMAKMKFENDRLVNEMNSNPSSIAGDNHSEKNSVVKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U828</accession>
    <name>A0AAD5U828_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000053">
        <property type="protein sequence ID" value="KAJ3225770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U828"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="268" mass="31212" checksum="691258FE03E5FFF0" modified="2024-05-29" version="1">MYETFSVLKYIKNYNSSGAISNWVSMSNKNILVNLFDDKLIVKAFVPTEYLLENMQYSNLTITGDSDTYQNSVAFKYFNKTKDDYLKFHLKFESNVTCLKFYNIIKKYVFVGIENKVFNVEPQLNYSILSHHSSQNYRQIQEHSTFVNSIEPNITIKSLLEKQTEEVSSYTQSCSTQQINVNKEENDNFYLQNGRLSINNLQKDEIKSNTTEKNVINLKRKLNAAESSDIVNGLLKLTDVEFKREVENALKIPEFKNLLEKISHIIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8Z3</accession>
    <name>A0AAD5U8Z3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8Z3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034044">
        <property type="term" value="C:exomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015374">
        <property type="entry name" value="ChAPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31975">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31975:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09295">
        <property type="entry name" value="ChAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="659"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="731"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="773" mass="85230" checksum="A6BE29165AF5986C" modified="2024-05-29" version="1">MVVSNSDSSKLAGIPEFFENEIGECLAARTESLATFRELGPPDLCHIVKVNPKATVKEEQSQAWSGKALWKIKSGTYCSFDAFSRVDVRVEVRIPGGVECHIIDLRGEKHAITNPAIWSETAVSSVLRALLDDNDEPDGNEGAPLLGLRKLDPLPTPAAEKRFLEAASSEFWKASYSIDVRIGWQLGTDPDVQVATYFSNHLSNGIMKYFSESCRTAEAVKFFEPLFKRDPEVGAVLAKAYLASNQEISAVQCLYEALKKHPLSYGLLLVQIDFLRSKKKLDMALKLAKLAVTYAPSEYNTWAKLTEIYIEVGDYDSALLSLNSCPMFTFCEKDSHRMPPPARTHLPLKPDTVAKDEDIKKIPPGSGSVFDENDPGENEVHPELQRLPSLSLRGTFLKAYSLLIDICNKVGWDELLRHRSAVFVMEEEYRIHRALVEEREKGEPEEEEDEDDIIDDKPNAPPLPVGGRASNDSQRSINSSVNGMHSSGEGDGMEKVSLDSSADKKSSLNRKLSIDMLMQKIEIDNENKGEKEDSANKDNIRSRAPEFAHYKNNAAIGNNEQLLYKKTGAEWEIYGDLAMRLKHDDDAKECFKLCLEQKFSAKSLLKLLEIFSNEGNIQQTLLCAVKLAAVMDRAYIETTLIINMRGFHGFNTRTAFNRASQRNAPKHSKTSSNMNFKPSKSSTFSGMFSQPQRSTPASAFSAASFANFNKNFSTTANQQQQSAFENSSQKTTGVSNSSTSSASSVTATSTSGTSGVSSAISGTISAASDGKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9A0</accession>
    <name>A0AAD5U9A0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MCA1_4</name>
        <name evidence="6" type="ORF">HK099_007028</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9A0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="WW" evidence="5">
        <location>
            <begin position="26"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="372" mass="41508" checksum="93A78FB60AEFBA5F" modified="2024-05-29" version="1">MNTYPGGYSQNSLGQQNQYRPPNPPQQLPPGWYVELFDELHMDPMGRQFFVDTKTGVSHWTLPNVLPPQQPIYQPPAQQPMNPHVQVTKNENFGTALLIGINYTGTRAALAGIVFLCISLIRLLGCHNDVKNVKQFITRTYGYQDNINSMVCLTDDQTNPLFIPTRQNIINAMRWLVQDARPGDSFFFHFSGHGSKQKDKDGDEDDGYDETICPLDYERAGMITDDEMNTIMCRPLPQGCRFVGIFDSCHSGTALDFPYQYTPDGKIKERTAIKNIGGIGKRLLGDLNSGKVFNPTSLFGDIKNALGTENATKKTKETRGTRAYCIMLSGCKDVQTSADTAINGRATGAMTHSLMKCIQNNPSPTFFELLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-11-27" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9M1</accession>
    <name>A0AAD5U9M1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec39 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006472</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000056">
        <property type="protein sequence ID" value="KAJ3225639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013244">
        <property type="entry name" value="Sec39_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15922:SF2">
        <property type="entry name" value="NBAS SUBUNIT OF NRZ TETHERING COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15922">
        <property type="entry name" value="NEUROBLASTOMA-AMPLIFIED SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08314">
        <property type="entry name" value="Sec39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec39" evidence="5">
        <location>
            <begin position="754"/>
            <end position="1393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2586" mass="299386" checksum="4F028490932F784F" modified="2024-05-29" version="1">MQVENVENLLLYEIILLSTYKPEDSKDLLRKYLEKKKNNKSRWSFSSILNKTLTSDSIPKPLIKIINKVKYNWSLKLDYSGNYLAVFSENFLEIRNSQNHFSHPIKTLLRPDAYPNLRKISWSYDSKLIAVSYSDGCITVIKNSGQVLCTIKSNTDVVLNGKTSFEKKDFIGFLDPVAVLGIVNPKTLRKCVNDLEESHELISIDFSGYLRSYRFKLEDIDTKSSLKVNISDLEIFSLGTQIYREDKDNNNVLKFSHSFNFGFHYRTLYTGMIDCETLVLVGEVSSNNVVDTFSEWICLNKFPFYQLKSYNNQEFLSSSLNSKSKSIFKAFIRQSVSYLPRHLTSMEESIHTIELSPTGSKFLVVENPGNLKIFQRKPLKLLNEFHNDEILAMTGVLNNKATRFARSTEQENIGTSHNSTDAARSILSVAGWWSEDDVILSFTDGSLVIAKLPTLTNVLGSNAEKFYAPLSLQCRQGEGVFVLENKSETIRYRLSPNNTYVLVRRLDVTESSLQNTMNSKLAFLMKFSTIPLRLFMNAFLGDWEESEVSDIITFQQHQFSLYYIMKSTPLEAMYLKIQLKKYGAALDLAKLYNLDEDPIYKAQWLDLEVDEYSIKDYLSKIHEKDWVLQKCASRVPNNVKNAKLLLQYGLKLTNHITMVDVENEINEVLEEFEGPMSSVRNFTTSQETLADVKKVPVHTICKYRLLFLKYIDRLETHVSIYSPAKIFPSVLDQEALQPFDVHFFQFRDINLIELALNFAINGFVHGLEVLFTRYTEEVLPYRTMILNHFPETYSPVLYTILLPEVEAETEVLWKSIPWRKKDWTENENILEFAGWESEHFEGECGEIYPNTGSHIRQWYDNRARFIEENSGQVDLALELVELGIQKKVKGLSLLRTHLKILFYLVFDESFHCLEVDLSKLESMSHMEIYNLILTETNERNIVEKVKKIILPYIQETDKYSTGCEQIFYACLENASRNHLNWFISLLEGKSFFEPVLFGSPDLIADLILKCCYISEEQEDLDKSYLRILNCIPLINKKSSSTELNGWDHETNLNEEFNVILREKIDLLSMHIRAWEILRFYNLQTPLKWFLESQNIELQRKLLVKLARNAGEIKLRFRYFDADNKFWNTLLERLLELRELKILNLLKLEDIFSEYFVVALNHGKFDLIADLLKRAEVIDNLPFKTIEKLVLDAATESFDNSTSCNMHTGELMMATNWFVGYIDLKLLPESTACQRELALIEAIHQLGLLKVPLKSHQDADSLLLPIQIRLHPNRLELIQQALGLNKQYYVSAGLVIDLSKKLLGAATPIPKVKALIADSALDSSDVEVAWRLCKDLIGDLSFQGNTWRVCLRLAQHSKFRDVDKKLLLVSHVLKCCPSSSLHEALTLWKNLDLEKVKSNDLGLKSSPLNDSASSETLSSFLHKGLSEYSSFSTLKSASSPLKKELVPKLLDSTSTFSPAKNFSDIYNLIEQNLSSPTASSPTRVKNNVNLDALKFKYSFVNFYAPPQCLDINKNETVFNEQKYLERIYLERLLRLNELKKENNEICNDVTQEILENLCSIFLTMDFPYGIGYLLSLTYPTVQYKYLNSLEQNEHVEKLGCYLFSLSACLEITKQKNVFSCKPVDLVSIIENIDSKTFNKHSIAEKCFFATKFLDSLKSKRDIRLLNSLIANSSRKEDARSSRLEASDYRKKDDFKGTLKIKNKNFQEDVLLEGFEMEKFNDENYKKCFMIGLIETFDLKKLEDILKVSGEFGVERKMLLLSYFKWIFTTPHADNDSITKIIDLYQNELLLINDALDVISSVHSNIFGTSHEKLLIFYKLYLEVLESSPMIQINLKKHLISNIAERIKLLENFFLKNLLIKNEINFKTVLQVKHLGSKPLLSLFKPLIADHSINEILEIFWEDNILKNLSYFEMFPEEKVELVALATSEGDSIANNLNGFESLIFFTFFEIHVFQNDWHFAEDIKMFTRDIIKVIPRLNKEWLIKIVSEITVGEKASYVPVNQRIGFVLEVQSYLTNEQLEGKINGECYDQIETFHEHLKLIYSLQNAQDPNTDEKILVEWIRQLDLTFGLNLNTVAAICMRMILSGTSPYLINEICKLYKNLEYVGFYELYFKTINCVVGKPVDEKYFGRVFRKEVDSPVSAIDRIIKSVVKYVCIDLDAGWGFEEEALKEGCFGIVLQQLEKSLQDMLIQIGSDHQNEYSLQMKILDLVETNFGVAQRGVDRSESAKFVKLIGIIKNEWGVEIDTRQLINLDDFMILFSKLLTMSETFGNFLYLLQILLELEEMKFRDALDTSSVWKMLLIHLINANSFDLLQLSILECIKVNMYTYELEDAVLQHLKSVNSVQDCIKIQLLSKQEDIAKSVMLYLRNVVVNMDITAEYYSLDRRLHIILITKGFYKDLAPLRSKLERTLLNFPTRHQLDDEMVMFFKNFFELTVINLIAEKQFNYASLLLRKYLELPKCFKGGLSNRFRILRNFVINFQKENENVSNHIIFDSEKVDKFFDFKIFLASSLQHYGVNSIPISNQKTNFQFNNFQLELEIYLEVKLILSFVFGEAKFNQQKNFEPSIYFENINVKLQECLNVLNNCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAG0</accession>
    <name>A0AAD5UAG0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA exonuclease ngl2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NGL2</name>
        <name evidence="4" type="ORF">HK099_005141</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCR4/nocturin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAG0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF45">
        <property type="entry name" value="NOCTURNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="29"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="386" mass="45523" checksum="B42FA6DF45AE0B28" modified="2024-05-29" version="1">MVLREFLKVPREKKDEIIKNSNDVKLSLMTYNVLAQGLIHRDSFPDATKLSLKIKHRIPKVLSEIKFLNPDCACFQEVDEFERFYKEFLIANNYDFIYQYSHETISSLENNTSECPPETVHGLLTIWKKEKVKLIDYQFIDFDNHELVFPTKITPYTKNIATICIFEFLNDLNKGFAVTNNHLYWRYQAVYEKLRQIYVLLTEVKKSRDRYNFQFFCCGDFNFEPMDIPYYILTRKELSSELRNTAEIVKHPGSDRENPIVSDENGNGDIDYKEIPPEELIDKLYTLPKLKSCYYNYANLLSKERYNCNPQWKENEVLWTGEPAYTNYGPWKGTLDYIFMLVEEGPSKVILDSVLYIPTAEELKKSLPNEEFGSDHISLMANFYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRF2</accession>
    <name>A0AAD5XRF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002018">
        <property type="protein sequence ID" value="KAJ3199876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRF2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964:SF140">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="26"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="151" mass="17019" checksum="A3136CD518EAE78E" modified="2024-05-29" version="1" fragment="single">MKDSVKLENFSELVIDETKQKKCERVVVLAVDQSIHSKNAVNWAIKNLIHPETDQVILLYVRPDLRGGILSEERSKKDAEELIKGYSSILSERNIMFKGYVVVGDAREMIVKKVEEFKGDILVMGSRGVGFLNRVILGSTSDYCVHNCNCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRJ4</accession>
    <name>A0AAD5XRJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001880">
        <property type="protein sequence ID" value="KAJ3200554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRJ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097193">
        <property type="term" value="P:intrinsic apoptotic signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018796">
        <property type="entry name" value="COA8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10231">
        <property type="entry name" value="COA8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="54" mass="6624" checksum="8B1D05955D0A4847" modified="2024-05-29" version="1" fragment="single">SNIRLVKYINFPKNTSAEELAWRKEEEMLQLKHHNFWKSNNINFQNSLEQFEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRJ9</accession>
    <name>A0AAD5XRJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001863">
        <property type="protein sequence ID" value="KAJ3200640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRJ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="314" mass="35687" checksum="A65CC66968751979" modified="2024-05-29" version="1">MFEGIKKILYGIDESVVKDFFQVDELDNFFFKFKSVFAIGDLHGDYDNTVRILTHQQIIDKDLNWNVKDSILVQTGDIVDRGPGTILLYKLFQTLSKQAQLHGGRVVSLLGNHEVMNMMGDLRYVDPGDMQSFGGADKRKREWSKSGNLGKYLRKLNITEIVGDSVFVHGGINLQYAKIGVDNINKISRDFLNLDFIPMNEILIHPDCPLWYRTYATEPESKACMILRDTLDVLGVKRMIIGHTPQESGKILSRCNMSLKNDKDTFQPRLYVIDLAISKAYGALGQGLLEIKYGENFNNVSIKGLYFNEIVNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRP5</accession>
    <name>A0AAD5XRP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002201">
        <property type="protein sequence ID" value="KAJ3199050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRP5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="234" mass="26106" checksum="58757BA5FC032EC7" modified="2024-05-29" version="1" fragment="single">HNKDAHECVSCIKKGIPCIYRENVKKRGPKAMETTISTTLPSTNLISSNNLIALTTKPTALTSTKLTEPALPKCNCNCKPTSIPITNDLLFEDSLSISPTLTYQQSILNSPSSTYQSPVNSPSSTYQSIPNSPSSVTEIDTFLDSHQKHHFDPCSTLDFTDSPASYNNNPFFFPSRYQNKESFLKQDSSIYVNESKILSNSPHYQHHKNSSLVYNNSKPGVFNEFAIEQYLLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRZ9</accession>
    <name>A0AAD5XRZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001817">
        <property type="protein sequence ID" value="KAJ3200894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="270" mass="31268" checksum="31BD858E2D53A25D" modified="2024-05-29" version="1" fragment="single">EIDLSIIFDVKTNKKKDLSFSDFNLREEEFQLTEVVIKSEEPEEKEINYDLNDNETLELNGCLVENLVTEVVEPNPWNENRKFLKRMDSALELNNEEMEVSEYDVAENNFSGNFYDIDISDTIAVVENRTSLEILNDLENGEFFLREDLKNFDIEKNETEFNGDWQVIDQDLSYIQKKLQGDKKLTTLSSNVVYALNQDVDNDGFTINKLKVIEENTSTSVCTLDSLKLNADDQVILEHYGMTKENNLETYRQQPTGCFGIFCWLLSGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSG7</accession>
    <name>A0AAD5XSG7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="16">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_000819</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 16">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Membrane</location>
            <topology evidence="1 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="16"/>
    <dbReference type="EMBL" id="JADGJW010001200">
        <property type="protein sequence ID" value="KAJ3205484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSG7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000130">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF218">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 14 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="757"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="790"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="834"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="877"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="905"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="945"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="17">
        <location>
            <begin position="726"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="13">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="580"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="581"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="582"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="674"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="680"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="700"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="703"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="704"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="704"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3205484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="987" mass="112220" checksum="0F11A10AEC515C93" modified="2024-05-29" version="1" fragment="single">MLLHKVLSKDLIKGDLVYYEKGDKFAVDAVILATSYDDGSCFVDTAELDGETNLKRRTGPFELNSFKTVEHIKTLKGEIQSELPNQNLISFEGRLVLSDDVKLNSPESHHVIPLNINNLLLRGAVLRNTEYCWGLVLYTGKNTKIMKNLKKASLKISSLDNKLNRYTLYAFIYNLFLLISSVLLELKTYYSIKDEYNNELWYLGQPQDSFSTQLKSDILSYFAVYTYVIPISLFVSIEVSKLCQGLFMHWDKKMTFHRPLPDGTTLKQCMRPNNTNINEDLGMVEYIFSDKTGTLTQNQMVLSKFFINGLEFHEMKQLGSLKEALNSGKTVDGIPIDDLTMEYSILFLRVLSLAHDVLPTLDNNGGYVYESSSPDETALLNSAAHNGFILSNKVKIYTEIRTTFKYANNNQLLGADVGNAIKLQDFNEERFEQLFLLEFNSDRKRMSVIVKNPNGKIHLYSKGADNIMLSRLSKDEKLNPPSLLKEADKALTKFSEEGLRTLVLAWRELTEEEFLEFKVEFEEAERSLDGREEKIATVAAKVEIELRFLGCTAIEDKLQDEVPETIDYLLKCGIKIWLLTGDKQETAINIGLSSKLLSNSMNIHILKGSSFDEVYHNLNIIENSMKNTEANDIQHALVVQGETLGIIFDVNFKSEERIKFLNIGKNCKSVICCRVTPLQKASVVHLVKKNVKCITLAIGDGANDVSMIQSANIGVGIMGREGTQAVRASDYAFAEFRFLRRLVCVHGRFSYMRISSIIMFGFYKNCAMITVMWWFGFYSQWSGTLVFEEIFMSAFNIVYVSLPPLVMAIFDRDVNEDKILRYPQLYIEVSKSKAFWNLWTVLSWLLSALYHSAAIFWCVYLVNIDGNISETGRTTGYWAQTAFLGTPVLTTVLLKFCLTTKTFNYLHALSLIFSMALNSISIVILEYFGYSEIGNGIIVDVSVTYYLICILMPVVCCLPDFIVISFKRIFLPHDADVMREESRLDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSP1</accession>
    <name>A0AAD5XSP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000775</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001199">
        <property type="protein sequence ID" value="KAJ3205494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSP1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051836">
        <property type="entry name" value="Kremen_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269">
        <property type="entry name" value="KREMEN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24269:SF16">
        <property type="entry name" value="PROTEIN SLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042271842" description="WSC domain-containing protein" evidence="7">
        <location>
            <begin position="17"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="8">
        <location>
            <begin position="106"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3205494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="252" mass="28857" checksum="F54B37BF2EDF14B0" modified="2024-05-29" version="1" fragment="single">MLKISIILILCLFVNTKFLKPVLECGTGKKDLKNHKVLDNNNEKACIDFCYENFPGLPYSAVNDDTCYCLSLKEYKSITKGKKSDCNIKCKKKDSEFCGGIDAYAISPVYTCYKINNDPTLVRHLILIDSKNMSIERCKKACLNYNSILDRFAISDGNKCHCSVVTFDIMEDEVEYTLCNKNCPGNNEQVCGGEGVYNTYTKSMTDRLSCESKFEIYDDMVKNKKYHKPAIWRSFLEQCAEVHNFEYELPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTU7</accession>
    <name>A0AAD5XTU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000669">
        <property type="protein sequence ID" value="KAJ3213872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTU7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="433" mass="48395" checksum="2A063FE86CBE5445" modified="2024-05-29" version="1">MSLSTFSTAIPTTIFTRITTSSRSRITSIATSQPPVKPTSNSTSKSASNPITTSKPRVTRSTTTSTLATVQSTGDVIPTLVGSSTKETIFFTETRLPVNNSQNSFEGAFTPIIIILSIIVILVLTIIGICACKILPTQRKRQNRVISDESIQTIAKHSSISPSSSNGFNLPLDSQPNFTLNQYDNQGQFYRNSTEPYRNPYSGEEFQNFNQQHSNIPQRNSGLHNYTQDYQVLEQVGGRPQSLFLIPQKNEFVDNARLYAVTGENQYIVPNPSLAYYGSNQNLYEHNMYEHNVYEHNVYEHNVYEHNGYNADSSQIFSAEGVNVPYNQDVVQAPFSSDHSLKENNFPLQNNFGEQEAQVAEKMKQFTFNDDGLNNSASTTTLEKEKKIDLDINRYKGSISSKVNSKFDTDGASSIDNIMREDTVNMILKMSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUW2</accession>
    <name>A0AAD5XUW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytoplasmic dynein with WD40 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DNAI1</name>
        <name evidence="13" type="ORF">HK099_005559</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000439">
        <property type="protein sequence ID" value="KAJ3217185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUW2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:003573">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="494"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3217185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="572" mass="64278" checksum="F06A21F8346D6096" modified="2024-05-29" version="1">MKSTRRTKIVDTLAGRSLSTSSMKSVGADPEVNTGGGEDWLPSKTLLKPPGQCILNEKELNEEFTRILNANNPKAPHNVARFNHKEHIFKASPNVDHLVVHFEFDGYLVFKEDAINAEDGESSVAPAVETEEKKKPLLRNQFNFSERAAQTFNNPTRERSSNTEPPPTRVLEDEVTQFSIYDAYCEDALQKEKAAKEKPRAGKGQKDEEKPGILPSEAHNEDVYNKNAEFGKSIIIIERMANQNTYDDISQDYKFWEDASDELGDRKSGTLLPLWKFVCEKTKRKQVTAVCWNPKSPDLFAVAYGSYDFSKQGPGMIACFTLKNPSYPEYLYITDSGVLCLDFHPQHPSMMAVGLYDGSVMIYNLQKKSEGPIFKSTTSKGKHTDPVWQVCWQKDDLDDNANFFSVSSDGRVSQWTLIKNELIHTDVIRLSIEALNNPASVIPIKHDEERLFDLAEGCCFDFHKKIDHLFVVGTEEGKIHKCSKAYNNQYLLSFEGHSMGVYTVKYNPFLCDVFLSASADWTVKLWDHNSSKPLMSFDLSCPVGDVAWAPYSSSVFAACTADGKLNDVGSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUZ5</accession>
    <name>A0AAD5XUZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000423">
        <property type="protein sequence ID" value="KAJ3217513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUZ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="76" mass="8461" checksum="740CB322E556F8E2" modified="2024-05-29" version="1">MPFFNGTHLKNNTEVKEAFLRVGSPEIYIDDMLGILPCPISVSIDTLYQSSKSLVDNANSNSIEKKKDIKTSDNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVL5</accession>
    <name>A0AAD5XVL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine/threonine-protein phosphatase PGAM5, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Serine/threonine-protein phosphatase Pgam5, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PGAM5_2</name>
        <name evidence="6" type="ORF">HK099_002285</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001740">
        <property type="protein sequence ID" value="KAJ3201359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVL5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090141">
        <property type="term" value="P:positive regulation of mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051021">
        <property type="entry name" value="Mito_Ser/Thr_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20935">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20935:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3201359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="31032" checksum="3CD8CD87410159D7" modified="2024-05-29" version="1">MDSTHLIALNVSSIVTIAIVTAGIGYFLPRAEVVDYKKLNEKKEVTAKPFTHPKLTNPESLWDNDWDKRQPLVESKSSGKIRNIFLIRHGQYSASEKDIDSEMILTEVGKKQARATAARLVNSGLVFSKIMSSTMARAKETAQFIHDSFPDVETVESDFFREVFPIDPVPALPVEYDFPRSDKFIEEVAAEAGFRKLFYRPDASQAQQVTNEIVVAHGNLIRYWLMRAMQIETRAWARFGLYNCSITHIKINEDGSVKAVSIGDAGHLPQDLVTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVN9</accession>
    <name>A0AAD5XVN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cytochrome-b5 reductase</fullName>
            <ecNumber evidence="4">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">YCK1_2</name>
        <name evidence="19" type="ORF">HK099_004397</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000308">
        <property type="protein sequence ID" value="KAJ3220313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVN9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000032">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="19" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="43"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="18">
        <location>
            <begin position="519"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="410"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="566"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="567"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="568"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="583"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="585"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="591"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="634"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3220313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="760" mass="86333" checksum="03D8336FADC9A18F" modified="2024-05-29" version="1">MLKSQNSPTTNYVGSPSPKQQLQHSSPQKPLFIYPLLVGNNQFKVGKKIGEGSFGVIYNGVNLKNNLNCAIKFESKKSDAPQLSNEFRCYKLLADTPGIPSVHYFGQEPLFNVLCIDLLGQNLESLFDLCGRQFSIKTVAMLGIRMINLIKSVHEKNLIYRDIKPENFLIGRTPRTNELHYTAGTFKQKEIFIYHIFTHYIDFLSFHNTEFPHPTSQIYLVDLGMAKQYRDPKSKIHIPYREKKNLTGTARYMSINTHQGIEQARRDDIESLGNVFMYFLRGNLPWQGLKAPTNKQKYQKIGEKKQCTSVRELSEGFPEEFDKYLIYARNMKFEDEPDYDYMISLFKSVLYNIGEEDDGIFDWMLEMERQLKAREKRKRQEAYKANSILTNEKDNSNLSDHHYLKTNQLQRQISLSKPERSQTPQKHRERNPSFQSLNTSLNVLNYGTDLGKNYSKPNLDKNDAIVETTKKGHTTNGKSSSNLILGATAAAIGVGAGYYYLQGKKPAIPDPAPVALVPDTFVDFKLSKVEQVSHDTKKFTFELPGNHELGLPVAGMVMAKLGKIVRPYTPISPKHANGYFDLLIKIYPTGKFTQEVNKMKPGDVLQVKGPIVKWNYKPNEFQTIGMVAGGTGITPMLQVIREVLNNPQDQTKLKLIFGNVSPKDILLKDELDKLAQDPRLEIQYIVDKGDKSWTGKTGYVTEQLIKDFLPAPNTNSRILTCGPPPMVNALTGPKNPDFSQGELTGLFKKLGYSKEEVFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX75</accession>
    <name>A0AAD5XX75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">U3 small nucleolar RNA-associated protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UTP13</name>
        <name evidence="5" type="ORF">HK099_007958</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000823">
        <property type="protein sequence ID" value="KAJ3211627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX75"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF0">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="460"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3211627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="543" mass="62398" checksum="5203EB10B846BF59" modified="2024-05-29" version="1">MDISKQCDKTVLMKSSGYEKEKILSFNDENNRLEMILVSSDDEDSSSFDSWDFDTSILSSNINNSANLGFKFDKIEKYETFAEESRRLNKVVNWPVYNFEEESWKTTSIQRNEKKKKNNNFKYIKIKNEFIERHFNYESSKKICKKKHNNWKSFSKVQIGSSAVNKTLFLDNSSTVAVAYYAEKSEYNNGNNLGIFNWEKKKYYRLLHGHTYQDAANFEISSTVDDIIYMNNILYTCSAFHNVIQLWEYNVDLNSYFHINNMEVHPSANFGANALCTDEKNNTIGAALKSGEILCSKIDNPYVIHFENVGLHGSPAATSIVNGHGVTANAFLCGFENKRGHENIMLIDKIKVLPSNKYNQPITVSDLAINPQMQVGGWTENKSSNNYYETLRVFDCRIKKEVLLISSEQNDVNRVGYSYDGEFFYSAGENSQVLVYDSKFTKKPIYKLSHPHNHIRQEGVRSVIWTRDDFLFTGGQDDLVKIWDMKTGNLMKEINFGSSITSMSLSNDEKYLCVGLESSKVELLTLGSYKAIDDIKFFPEMNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX88</accession>
    <name>A0AAD5XX88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Small ubiquitin- modifier 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SUMO1</name>
        <name evidence="2" type="ORF">HK099_005976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000491">
        <property type="protein sequence ID" value="KAJ3216205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX88"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="44"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="124" mass="13480" checksum="3635F109225A96DB" modified="2024-05-29" version="1">MRLRGESTPEDNEMEDGDVINAMNTQTGGADAGPATEVVKAEHLNLKVESSDGTQVSFKIKKATPFEKLFNAYAQKIGSDRNSIRFSFDGVRVEGHQTPESLEMEEEDVIHATVHQVGGCISVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXL3</accession>
    <name>A0AAD5XXL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ADP-ribosylation factor protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ARL3_2</name>
        <name evidence="5" type="ORF">HK099_007394</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000710">
        <property type="protein sequence ID" value="KAJ3213438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="77"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3213438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="144" mass="16439" checksum="2063A996CA694B63" modified="2024-05-29" version="1" fragment="single">GLNIGKIDIGRNRLNFWDLGGQKELQKIWKKYYTECHSIVFVVDSTDRERIEEVRLAFENVITNDSVEGVPVLMLANKQDIEGSLKVHDIKEIFNPIAVKLGARDSKVMPVSALRGESVKEAVEWLQIRMERNSGNRPPVYRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY72</accession>
    <name>A0AAD5XY72_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006492</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000563">
        <property type="protein sequence ID" value="KAJ3215161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY72"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022232">
        <property type="entry name" value="TPPII_C_art"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046939">
        <property type="entry name" value="TPPII_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048384">
        <property type="entry name" value="TPPII_GBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022229">
        <property type="entry name" value="TPPII_Ig-like-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046940">
        <property type="entry name" value="TPPII_Ig-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12580">
        <property type="entry name" value="TPPII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12583">
        <property type="entry name" value="TPPII_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21316">
        <property type="entry name" value="TPPII_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tripeptidyl-peptidase II galactose-binding" evidence="3">
        <location>
            <begin position="55"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl peptidase II second Ig-like" evidence="1">
        <location>
            <begin position="203"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl peptidase II C-terminal" evidence="2">
        <location>
            <begin position="451"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="855" mass="96929" checksum="9AA57C6D934C53AC" modified="2024-05-29" version="1">MISVDPTALEPGFYFGEVLLFDTTAIPHGPLVKIPVIVCKPNLCNSGFKVENLKFEAGTIHRNFVHVPLGANYIECVLKCKPKATASFFLVDLTQLKQHSRFNTFQTRGKTYLQNAQASNSEEYIYRIEANVIPGENLEITLAQNWSSKGESEVEFKVKFHGLLLTCSGNLLGMDSGFAGYGCNGLFLNSGNTGFTRIDMMAPIRKEEFSVSPTLSTLRKFVRPNNQKIITLKSRDILPNSKQTFELNLDYEFKVPGGEKVKVTLNFPNFELSVYDSVWDDFSYQVFNSNNKLIKHLSIYKEVLNLTPGTYKVKACIVSSNTEMLLKWQGLNLVTDFSLSKPISLAVYSNIGDLSSCSKSSFNEKSIKRGGRTTFFIGEYTTPVPEAKQGDLLLGEIFKSVGGFKLKKPLYSIAYQVPSEFKPKEENLISPSLKKPDFEEVIKKDDTTLLNEAVRDLEIGWLKKINDEIKREELFKKIESQFPNHLPLFVKRLEILGEQFNKYEKDLSATSSLLEVSKKIIVWADKILQLIDQKEVRIYFGTRHDLKIESEKEKKKEVDLQKQSLILALGNKCNSLRKIVDVKLNSFIEKSKLNKEMDLFDDTLNDLYQWLPEPATDDGIYLINWVWRQKSNGYTGLALKAINKYLGNVKNTDSKLKQDLNLLKIDLIKDLDWKIWKNYFDLWYLKNFPETFEDTKNLAKLNTPPAVEKDILKDKELLLKNSAILLKCKNSCWEESETVTVYVMKEMKTGAKNIIVKGEKDLIIETVVPTEILQIDKEINENSFSWDKETVAVRFETSEIILASVVTLALLMNPVTAGGNCSPCDAECSNSCQRQCQGAGVGSQSCYSTCYCRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYC4</accession>
    <name>A0AAD5XYC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000530">
        <property type="protein sequence ID" value="KAJ3215627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYC4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="110" mass="12319" checksum="1E65F277B61B731C" modified="2024-05-29" version="1">MNGTSEATESKEKYTTGISKDTLQIYVLLFGLSVILLITIILIRIFRKPKFSDSLQTSTSIMEIGETHLPPYNVGNFKISNDTNSEEVVIEYPPPVYMDQPNLKTKTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYD2</accession>
    <name>A0AAD5XYD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000754">
        <property type="protein sequence ID" value="KAJ3212989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYD2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="642" mass="74658" checksum="12E2C96E605B001E" modified="2024-05-29" version="1">MSKSRIWFQLVDSEGNPYKKISPSSVLVQQDTNIGDLRRLIKEEYSNILFTRQLEIYENVDKLSEEPVNKRTPVFKLDNTEDLVVVVPDKPAPLLKNWSFEIWEKPRVLENLEEKFKFIEVDVNKILFTVDGIKRHPENLPHLLIDDLGTVQSKCLESLSSCIANPKNRVTFILGSSGCGKTRTIFEYLYQHYGIFLTYKNSGTQLPGSMDLNYVIERIQQFKKGDVYENQEYLAHLVKCLVAARLYMFKKIYESVKITKETWLFIQLFPKRYSNTDEFFETIIQIFRHLKSQDLEAMLNGLIEYFKKVSGNIPIFLDEAQALIDTEFDKFPSNSDALKRCSLLNAIKNAILAIDTDIVLIPTGTGLSITDISGDNAKVSGFMKSSTAKVLPAICIVDNCWENIDEIQDFLSQYLGEKFKLFPEHALYFIGRVRPLALFIEFCLVNRTKERNFDVNENFKLFVNEVTASNREVWSVYRLFEEERLKNNSLLPLLKKCVFFKVCFDRPFTMLVSEDARLFERAFGILRKVEEESNELFVTVKELFVLHSAYNYFFKKNKNFLDEMAQIRIAESFNPQSRGYLWEELTNNCSDFMNCENSKIFRQECYPVPLFINCKSNKIITVLVRSVQEECIVFPSSGKCWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYH9</accession>
    <name>A0AAD5XYH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulator of G-protein signaling 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RGS7_2</name>
        <name evidence="5" type="ORF">HK099_007411</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000715">
        <property type="protein sequence ID" value="KAJ3213409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009968">
        <property type="term" value="P:negative regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008277">
        <property type="term" value="P:regulation of G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047016">
        <property type="entry name" value="RGS6/7/9/11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047017">
        <property type="entry name" value="RGS6/7/9/11_DHEX_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040759">
        <property type="entry name" value="RGS_DHEX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45746">
        <property type="entry name" value="LP21163P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45746:SF6">
        <property type="entry name" value="LP21163P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18148">
        <property type="entry name" value="RGS_DHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01301">
        <property type="entry name" value="RGSPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0734">Signal transduction inhibitor</keyword>
    <feature type="domain" description="DEP" evidence="4">
        <location>
            <begin position="188"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="472"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3213409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="642" mass="73697" checksum="CED1C8B8782B4E48" modified="2024-05-29" version="1">MPQAPQLLVTTEVDNNLPFSSITNNEKIAITQPSLSSSTPIESKLIKDIKETFNTSQSKLPHLNNSNNNLSPLTEAEAANVRKELRTSQYSNSAVINHTKSQTKSQTASGSHSSQGTRESTINPSIETTNIFLDEKPFISYMVTKYKNDAFYSMDDLSTANDQQKKLSGFVISRNKKLISSVLKMTESGSTLVFKDRKKKLITKFDYCATGEEIFKWFLNLKGGGYMSNEEVCSHLQYLMEYGYLINPDFETTFTADQRLYTLQSPLLWHRDNWKPSEEDYVTYLVRREKSSGERLFLKPYENDRLMYFKSKLKEKWDTIEIKVATQKVYFDKLSKSEQRKFNVQEFGFWQYFCPDPANSYLAKDKKIALEMERDAGKKGCSADVFEQQLNGELLLKYLIQKINFFTHNLTLNFKKSSSSSKTIITHCDLFLPTDPMILGFQQNPWLKNDALPAKVERKTASVYDVRIWVNNFLGLLRDPLGFAVFSDFIASEHSTENLNFWLKVEELEKLAENRVDFTAGALEIYKNFISCTAPEEINIPSHIKNVLHTEFLEDNIHKLPYNCFREAQLHIQTLMMNDSFPRFCSSDILANYFLNNVKDKHKFKGSLNGCHKPGSVMALKLDKNDRSKSTISLSNLLASTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYL4</accession>
    <name>A0AAD5XYL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Chorismate mutase</fullName>
            <ecNumber evidence="2 7">5.4.99.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ARO7</name>
        <name evidence="8" type="ORF">HK099_003828</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:13898"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="2 7"/>
    <dbReference type="EMBL" id="JADGJW010000257">
        <property type="protein sequence ID" value="KAJ3221022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.590.10">
        <property type="entry name" value="Chorismate mutase, AroQ class superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008238">
        <property type="entry name" value="Chorismate_mutase_AroQ_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037039">
        <property type="entry name" value="CM_AroQ_sf_eucaryotic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01802">
        <property type="entry name" value="CM_pl-yst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21145:SF12">
        <property type="entry name" value="CHORISMATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017318">
        <property type="entry name" value="Chor_mut_AroQ_eu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="Chorismate mutase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51169">
        <property type="entry name" value="CHORISMATE_MUT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="263" mass="30448" checksum="C499F919647BA657" modified="2024-05-29" version="1">MNFTKKNFTLDHIRQELVRLEDSIIFALIERSQFQKNDIIYKCGGINIKEFDGSFLEYFLHELECAHAKVRRYTSPDETPFTTNLPDSVLPPIQFPKLLVPNNVNINDQLMKIYINEIVPKITDEGDDGNHGSAATKDCHVLQLLSRRIHFGKFVAEAKFNDPLLQPKYIELIRNKDKCGINDLLTNLAVEEKLLRRLRRKAAIFGAEIDGDGIPTLKEEDNKIPLDVVCDMYEKYVIPLTKVVEVEYLLERLKYYPSFVPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYU4</accession>
    <name>A0AAD5XYU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL30m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006899</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000626">
        <property type="protein sequence ID" value="KAJ3214377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYU4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_uL30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_uL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="5">
        <location>
            <begin position="101"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3214377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="256" mass="29285" checksum="F3DDB91DD8DCDAC3" modified="2024-05-29" version="1">MYITSLLLKKLDITPKIANAAILNQKIPVSPAISQGRQHLKPISKNPNIKVFRYKNSRIGYKIKKDMMFCTSNFEKFSDATTNAITKPLIKNDTNYPFSYYQITLKRGVIGLSRDTKEAVAALGLVKRFQVVFRRVEAKHAGLILKVKELVDVKLVNSIPKVLKIEKGYQKANNTIGYYNLSTYDYLDRKEAKKYDPHGFKTDPTVPQKNKDIIKSNRRPRLYRCGFGHEGDEDFDHPSAVKDIEYGLPIVEISEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ14</accession>
    <name>A0AAD5XZ14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS8</name>
        <name evidence="4" type="ORF">HK099_001421</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000014">
        <property type="protein sequence ID" value="KAJ3227572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025941">
        <property type="entry name" value="Vps8_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF8">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23410">
        <property type="entry name" value="Beta-prop_VPS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12816">
        <property type="entry name" value="TPR_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="2">
        <location>
            <begin position="282"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 8 central" evidence="3">
        <location>
            <begin position="667"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1599" mass="183630" checksum="A1F1C7B78A4D9407" modified="2024-05-29" version="1">MSSTEKDSFIVMSSLNEFESNESEYYFDRLLNQLHTRFINLLIPETLLTTVKKDVLKNTVSDLNEILNIIESNILNNKNNLKDEIFQSNFKIEEFLNLKFKIKKEINLYNQFYNASSANLSLSNILSSSSAITSSSESENNNTYKSRFLIHKKSESILSISSLPNSAHIFNLNLNETSSGDNFSNENSTTSKLTVGGTIKQTPPGPFDTFKWMELKKVNTHFTNLKDGVGTQSVFLVSNKIFIGTSRAMVLVYDLSQTFKSFIGDVNNAGNQEKINFKLYIISGNLGAVCSLAISNDNNYLACGHAKGNIVVWDVRIKTLVKQILPLETPTKENDGHQFGAPIIHLNFYDTVGSLLSADIESSAFIHKINSMFYIKSSATIRIHSKSSQSSASTIPSTLYSLKLIKVGGSTSNAISIFALSSPYKLAIFGTSPKPEVIFRHTWNKTDLEGKVIPIIASMSCLAWQPEFKKSISSCVISNDELVLYNIVVNCQIEKCSIKDFEILYHDWHSSLISGLNNVVPEMALGTSVQSYKSRLFVMARDGLYVGSLQSWDSRLNAMVRSGNFKEAIDVGMELYFNKKTVAVVGLPLDGVVRKRIIRDFLSQLLVSYVNMAVSGFEASTPAENEEISMYQDLTLLTIEVCLTIETVDLLFFELFERFDEGGLGSVFLTQLEPYIIFDKISKIPNPVISTKYLQLYENSEWSGEKLEALLLHLDKSSIDLNGYIQTFKKAGLFTGLIYLYSTVLGDHVTPIVELLLLISSQSKSAESKQLDFENSFTLSWRNTANIDTHSLIYLLFVYFATILCGKNFPLGDMDCNEDILKAKSDIYNFIFSPSFTTVRGSVIAVGTPPFPYLKMLLELDTSEFLKVLGIGFDDSSLNGDLQMKEMLQNGMDGYQSRQIAEINRQFILDSIFSIMEVNDGLFSINNLISFYCFVCRNYSKYSTFLYFEVCVLKKVVYTLVESTSQDTKIERESAILAILSSHDFQFTAEEEQNLLEHLEKNKLFKVLEKFLIKERKFELVLMCYLEDDERKNESFNVFLQYLLHSDLTFTEIYNLKEKFFEIECLVKFFNLNNSKFCFLLLQYFPKDKCEFVFNEFKKFDVNLSFKFLNSLFGQIFKFDFNNETHLTSESSSEEKKSNLLNESDNDSESKVDLNMIENKFSINLFEQHLRLLAVAKSEAAIIRYLEFLNKLFDNKNKYPFNLENLLDIFLQEKLIYSACWILDKLNDTKKSIAQLCTYYKETFMIFVQEKNQDILSKVKIELMQILEFGVNLLRNKFSFYKKNNDSEMLWLTIFETVVEGKISVEVPNAYEILTKNNTSLELVVDFNARNRNDDILQYCDSACTFVIQAMIGYVSLHKIFQQLILDKKQQDACNLNFGKNKKLIFSLLENYKFEQLTLACFNKIIVDDLFKTKKFLFKKMKKFVSPKFNQCSVCLKSIQVHDNDTTLNDYKEEKIICFSLCSHLFHQNCYINLKNFSSSTKKRAKCADTTEFDEMYCIYCNLNDITLQKFRHNYVEIDENLDLTEKHMNLEDFVTDISEVKTDFVEEVFSRINELKEFKQNKTTFEVFKGLPNANNDDSNDVIELNENRFDEDLLYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ25</accession>
    <name>A0AAD5XZ25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphate system positive regulatory protein pho81</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PHO81_1</name>
        <name evidence="7" type="ORF">HK099_003504</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ25"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SPX" evidence="5">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="285"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="318"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="351"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="385"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="6">
        <location>
            <begin position="664"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="506"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="526"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="975" mass="110378" checksum="9F87625283BF912A" modified="2024-05-29" version="1" fragment="single">MRNLQEKKKFIFNDDKKIKNRNSLYSLKDAFEHFQIDLIRLKNFVEVNNTGFRKILKKWDKRSKSCTKEIYLSRQIEIQPCFNGVVLTELTDATTNNLQELESILENLENGKSINIDKYKKNSNVGLYDNEMTYNYSFNNSSEEFLDVETDLIKSINKGQDNLINSFLQNTGERDKLDQEFFSRIFLSVCEKANLELLKLLLQTGQVDSNYSNDINNKTCLHDIAIYGRLDVFELCFKYTNPNLLVLDVYGRQPLHYASMYGHSELVKFLLKITKCENINQVDYEYSSPLVYAIMGNHIKTVEILIEMGSNLEPNSATALIPLCLASQFGYTAIVKLLLEKGANLNASNSDGLNCLHLACREGSLDIVSLLIKHNADVESKDSFHSWTPIFYASSEGHYKICEVLINAGAKVDVKDEFDWHPITYALYKGKIKAATLLVLNNLKDDDNSFTPLSSVSIPSKIPNLSENLDFNVDIDDIPSLSLPPGHNYLEKQSYVQISFEKKHQISAHHKKRKLNNTEYSRFKSKSQNNPTTSLNKKNSPLSIFNSQQLASLQLIISSKPEVGIPYSVVLPLDQDDSEAFTFIVDENKLDETSIQFDVFPTFGTKVIGRGLALPQNLGLSGLKTTDYVDCTLPLFDLNLKLVGEINFECFKVLPFEHSCLSIGGKVETYWKSTTNEKKKKNQLSVNNDSKSANLLEVVTASSLAEEYIEITVFVTNDAIPIILNDLFIRNNEFELGFLTFNKLKEKFSIFEENLQLLKSELKKDEVKQNFVEVGRLLNLGGVTLDFVLEILPAGLGLSIDVHYPANEKQSNELSNSKLNSHLDAILKVVYDQVSKSSDGGKKIIFSSFNPKVCTGLNWKQPNYGVFFRSKCGYEDEVDMEIQDSTSDIESCNSSRLEYFEDKRCGSIKEAIRFCKKGNFLGLFCDARPLVRAPELIKTIKESGLILATFGKVNNEESNLMLQEKSGVDALVNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZA1</accession>
    <name>A0AAD5XZA1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001681</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="6">
        <location>
            <begin position="800"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1435"/>
            <end position="1519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1789" mass="205982" checksum="852868BA96E3CF62" modified="2024-05-29" version="1">MLKHSVNISIDDLNNPSEQYEVYKSEKILSESSLTLDNPTTIYSKTSNLHLASDVDTSQTQLNDLIAKNMQPSAKFTSADSTVQGYLSDSSLSSIEGLEKSVARKYSTRQSKRINNSAKKQLNGKKGNNKHYSVGVINRTGFEGLASCAEPSLELNSENKNYLENKKTSQVKEDILKDSMKEQKTHTSFLKRTNRDMKYEDMSKGKVIIKLKVPHSRNPKHSAQFLTKNRKGLGISDSIGSSKKFVDRDGTMLCDIEIVNDDDANRELKDAGLTITSPLPPNQYRILENFEEFVLNNVAYKVPTLKIKLDIAKKPDEEEITKKKIIHEKFNCFPLGLGIEFNNMKFRNLFYKNGVFKDLACTDEEVDELNKLSSKLESWMDCKTKGNKDLNKGCLLQQVRFMEDANLYSNIQSSQLSASVPSEANKKDLKIKIFSESSNSTTKRNPLKQLFFLVANSFRIFKSSPKSTKNFSSNRNEVAMVLVTIGFLGIFLGTLVIFGSESEWDQLLDMKNTKWLSDITKRSTIIPLPQERISNINCRSKHKICQVSNLYFLDGNLHAYLGRNATINPYMLQNQTIITGIGFGSPSIKPVLAETYNKETWSENYDYHGNSEKSSSMKNTEIENGSLQSQSKISLADSIKRNMIILPLIIHFDDPPSLSTESVKYISEPTAFFSVMWDNLFRSIYAGIGAFNSLLYFDTLNFYGRNRMVVIENNKPSRFVKDILQFASPFPVKWHKELEDCLFRSATLGISRDFGIAEIKVETQINLTERILRRNTAYKFFCKSLKSRILDQRDTKNKKILKLIRGSNNMIENLNNFSSFDVSDLITQDGSENDTDEDDINEFDEDEIISMIPVFESTLPLPVMTLILRDGNTRRIINEKKLVLILKKLPVKLGVYRFGTMSFSDQMAIMDQTNILMTMHGAALTHLLFLRKNSFVIEMFPYGFRKTVFNNMARIMGHKYLFWQNTHLNNTVFDYKYVEEHKFSNLSKEEIVSKPINWRNMDSKNYWRNQDTKIEFGEFLNIWENSIVKNSVDFSLHDTIMFQPSGFFTEQLASFRVACALGKYLNRRVVLPLLGFQIAAPTNDDSHRLFHVAKVNWRPMEHYFDQKELLGLKCKWISHENFQNLNQNRSIQKIRTLKDQVFFDTQEQIAKYYNEVLGLPFVSILKEHSIHPQFNAQELKRKYGHRKSSTLAFGELPISLFDFNAKDPEELEEESRLQSLRKTSAGVDNKQSELLRRFPNAKKALTLLGDQSNAKKNEKTEGLVFERLQENIFNHLNFREELWTVAKDAISKINGKYVAIHARRGYIGKKCQIMIPKVQSRWQSLTQEQLQHDIRECHQNTRKIEKNFKRKVRNPAVKYVNVTAESLKDVRNLQLDGYKITEFSQDNEEIKPYIENEVDDNEEEDDSIDTTIFEAIIQEAIVEDDESDAAADSNHSEYTRMHEELKNTNNNLNEDMTASNNDKIELIVENNEISVPNLFEKFEKQLEGTKGEVEEKTLEEELELIINESKQDKNNAKIEDEDSIDDDSEIIVQRPKLEFVVVNEKADEIEDEVDFKVENNENVDGEIQIPAQMAGINFKVTNDIRIDLYSEDLRNLKSNELGMNSVVNGEQREKIKNPIEYITQKDLLEVQHNYVPDDLKNEEDGDGEMEKNNILTQELDQEIDWDQKVGKVFLRKRDPSITSKIYIATDDLGSVASKKEFQNLGRSSGWESPIFFNDIISKKVIASAQESKDKFVEFLDDNSFDPIDLSIIEIIICLEAEVFFGNRFSTFSQEIFARRQAKGKKSYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZN9</accession>
    <name>A0AAD5XZN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">protein xylosyltransferase</fullName>
            <ecNumber evidence="6">2.4.2.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Peptide O-xylosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">GCNT4</name>
        <name evidence="22" type="ORF">HK099_001492</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>UDP-alpha-D-xylose + L-seryl-[protein] = 3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:12567"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132085"/>
            <dbReference type="EC" id="2.4.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; chondroitin sulfate biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Glycan metabolism; heparan sulfate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 14 family. XylT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.26" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000142">
        <property type="protein sequence ID" value="KAJ3223145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZN9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030158">
        <property type="term" value="F:protein xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050650">
        <property type="term" value="P:chondroitin sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015012">
        <property type="term" value="P:heparan sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003406">
        <property type="entry name" value="Glyco_trans_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043538">
        <property type="entry name" value="XYLT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025:SF3">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02485">
        <property type="entry name" value="Branch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="21">
        <location>
            <begin position="603"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3223145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="865" mass="100883" checksum="C75025B859A5A12C" modified="2024-05-29" version="1">MNNSDAEYKSSFNRTVSMIILTRRSYELGFLIFAFCIFEVFFHNHIYPKNTSRKQTLVHKKRSEPQLTTLEKSILPDISESLRAIKYSRYIELTGWKFCPTLEGAHFDALAHIYPLNGSLAEINPTKNMIISLIETQAKETFGSINLLLEEKNVDSLDLRRFSCYFSAEGTNGLVNLSETRFLKEINAKNYFPFLSLEKENVADLTKSYKHFNLDFNIKQDESLFDSFLDDNLNHNNNIVDVNRDKLKKTKKRKLKIAYLILTHEITSFHNIKLLINKLSTKDSIILIHVDLKSTELKISLENLLQERKSLGLLDNVFLQKKSFGVIWGHISVVHAQLEGYFELMDLAEWDYIINLSAYDWPLRTTADIYESLVKHNVTNWIEYWRDPESSAARLSRPHVALSDYKGIVHAFETGLRWWPFSTFHAFKHHQWMILHRSFIEHIRTDTVAMDVLAYMEHTWIPDESFFAIIAVNSPMFKDKVISNSRRYIKFEGGWHPIWITWETRYDFLIGDNPDDGYFFIRKINSSMEPLLLGWLDSKLFNLTPETPCRKDDIGYREKCFKEILQDAAAKSPDNAIILIPVNRGQINAALNLYCSLVRQKMHTQTLFLSFDAEAHIKLVEKGLLSYFNPTKIKGVADAQSWHKGSFSRMMRQKPIMWRMLMDIGVNFWQFDADTVIIKDFRPFINENVDIHLAIDEKDNLDFVLNNKPIPNTCTGMMYFKNSVGTRIFINKIQEKLNRVSWMEDQEAINSILRTEIFSQKPTIILDNFKIPSSFKTNQNINNNSNVNLLTDDGLPKPVIGFLGQMEFISGHYFFNREDWELQQYHDAITIIHGNGREDKESAFRPRGLWLLRNGNTQCPFDYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y009</accession>
    <name>A0AAD5Y009_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003827</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000257">
        <property type="protein sequence ID" value="KAJ3221021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y009"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="642"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="676"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="711"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="795"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="842"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="872"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="901"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="984" mass="109356" checksum="F188149609D71236" modified="2024-05-29" version="1">MNSANWLNQCFENENLLTIDCSSNKEQEDVTVQFNGTISNCNFINCPNIIIKDSIGITLNNLNFSSPNKEAKITIQHSNVVVKNSTFDTVTIDCSLSTCRIQNSSFLNAINAAAITAKVSPLIILTDVNFYQNTLTGGSDLEIFDTLNFSWIGGISEGDFEIESRASFYSSVASMENVKYLSKSQSAKIAITSLDSKIFLQHIQVKGVASFLVNKGIAHAKDILIEDIESTDQSSNSNGFLIVSFPPNTDSTYTTSSRFENITIRNTNTPGIILTSLNSFIDKLHAYNNTIQQTMFGFGSPDTTLRISNSIIENIIALAPVTQLVTTELNKNTTLIFENSTFASIFNENVNLIFFELHSHAKLILENTKITKINVGDGVLIQVQEQSMLKLGNGTDISDIYSNGIGSLIYLEDTGMVEIAESSSVRMQNNSFSARGSFIKISTEFFSYEAVNINTKGSKINGTIWIPSLMQCDNLFSRGLMNNVSGEVVIQSVPSKIRLGNVQNQFESFNQVSVQPFQHIKPFFVTLLDCTGFPATAAQSDELIPVVYLDSPVTAFGEAVKVILGSEAEFRGISFNLTTSNSVSVTVKGLGDTIDYNVTNPDWPTFSLTILECDATTQILVKKTDETLVCFPLCLISDTQRFSVLVILLISFLGFLLAFIHLIYNYSYFVIMEEAGIYFTTLIAAGNLSCILSVVVSYLPIGGIVCSLSSILKVLGYNLNFLGYSMRIFNTIQYRRRTIQKPRNKVSKFSFKPSNLKKIISKKVEKFSLNNINIKSAGKKKRGISNKELNKKSKIIISVVVLSISLIYLIFWNVVNFSTYKTVKFSTCVSEQVCETSLFDQFFIYYILGTSVLLSILALTQKDVDHNFNESGLFSFIFFNFSIFQLLLLMIPLNILNQTKLLMETLIIFVTQVASLVAVVLRPIYLCKFHEEYYQTYEEDWNASQMQSGAPLDSIKSSVYSHAVSSIPASTHIPPNNPKNKHVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0D0</accession>
    <name>A0AAD5Y0D0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein mS38 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000217">
        <property type="protein sequence ID" value="KAJ3221648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0D0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013177">
        <property type="entry name" value="Ribosomal_mS38_C"/>
    </dbReference>
    <dbReference type="SMART" id="SM01155">
        <property type="entry name" value="DUF1713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein mS38 C-terminal" evidence="2">
        <location>
            <begin position="277"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="39085" checksum="CB502A2FBC2B4413" modified="2024-05-29" version="1">MDKIQLMLRSQQLLNGPVLIPSKLVKLNGRKTFSRIPTLVKAPCLESEWLLSRARDRKLDMIAWKNWVAHPNYNTKGGLIKLKKSTSHSRDSFLKERNKQINQNSTSYSNLPLPNPVFFSGELLPDFEFKIPKNNQDMSFRNNNSDKDPLDFEDSEFFTPDLFFEINDIKNDENIHASALELKPNASKFSWVQLSQISKFQLKYHQRICGVNFYEFGETARFFKFHYAYGNRIGLSFIKFILPESENNTSKIVEETTTFKNEEIGEGKRSGPLQTKKIYSIIIIRRKKMNKHKWKKLRRRYRNSTRKSRSKRKRNRDRLRKEYRELGLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0M2</accession>
    <name>A0AAD5Y0M2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002706</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000192">
        <property type="protein sequence ID" value="KAJ3222091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0M2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="282" mass="32852" checksum="A3B0C6175B28DCAE" modified="2024-05-29" version="1" fragment="single">STTHNVNPFKMQLSNQCFSTLNLSSEATPTKDTNINNKVSDNFNLKNLKKKLSLNNNIIGPANTKSSQQQFLSNNNDSNYNTLIETTSSVLYPSILQPSLSYINLNNFSSNLSNINHNPSLNNKLIKSTSFTQQQVKKNNLLINLKIEKKSLKNNLKFWNNLIIKITKLKGQELVNIKLKFRKNFSFYQLFFNRSNIKNNLEYETFRDNNVTDFSFCNAFENEDVNEDDEDNDEDDTENDFYFDENSTFDSIIFNSIKAQYLFCEGCLKRLWNVYQLVFKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0T6</accession>
    <name>A0AAD5Y0T6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">B30.2/SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002339</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000177">
        <property type="protein sequence ID" value="KAJ3222395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0T6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045129">
        <property type="entry name" value="RNF123/RKP/RSPRY1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13363:SF5">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13363">
        <property type="entry name" value="RING FINGER AND SRY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="6">
        <location>
            <begin position="404"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="644"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="750"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="644"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="677"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="752"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="971" mass="109128" checksum="1A075EF28726F670" modified="2024-05-29" version="1">MENHDAQYGGVALLLNLATLSVPLINEMADVGVLEMLVDLILESDRDSIQTVSSKTLTAIAKKCPHLRYQLVQLAIVPIINKINELIPVCINSIFPEGYNVESPTSPDTNRLSTTTRLQEGANEAITVESFLSNEDKAENSNKKLENLKIPEVDLVLTARLIGLLDSLTVFVKTDFFDILHYERWGVDGNKEVVSIQLESLLSQELIDHSKQLLDILVLPLLNEDVIMAAKSPQQNTPTTITPTIVKELGSEEMDLYSPGIEYIGNIRDEFLGHVQSSLSSSFDGRIGRHTVDMNESIDSNIEEKEKKLEEIKELKDDVAVHVCSLISSLMKYNNVKEFLLQEKIFTVLIALTQEKRVGLYEQALTCIALCAKEDGIKKVSYLQVPYIFTLILKNLIMENSKLLNFFCEVFMEKSCNFTSELNMNYSSVLKNQKYFKLDEVDKTFSLMLTDWEIRNESWTFESIRSNLFLPASVGGKYGYEVVLKSDGIIQIGWATFDCNFDPEAGMAINGTGVGDDVYSYAYDGQRRKKWHGTEPKNNSYGEEWFAGDTITVLIDLDKSEISYLRNGIDLGVAFENINSDANWFPAISMASNQGCSVNMGNELDPLSFLPSKYLPVASLLFPKKMKQNEVNVTNSLGEFFRSDAAPSGSPRSSPLSELSPSSSVGSATKPFGLKSDSFSLEGDSQQSPGKLSNVIDRSSVIKEEADNKNEATLGQHQNFAQGYSNVSSKRGDSHYDALENEHHLNVREEFSNFSSIGNGSQSDNREREVVSPTTSNESYDIRSQSPVSTINSPISNADETIDLSFYFEVAVGLKGNHEKMYPQIGIYDRHFNNFFVFFFEDKIFLFDIEQTDPEDHEFFDFALIEYIKNVSTGLSPTTSAPIKLLKILENFPLKEGDVIGVGLYLNDKKILFTFNGIPLHDLTVKNGVKQRLYFPYIRNISRFKVNFGQNNNFCWKDVNCFNLFSYVDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y117</accession>
    <name>A0AAD5Y117_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000159">
        <property type="protein sequence ID" value="KAJ3222785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y117"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="HEAT" evidence="1">
        <location>
            <begin position="120"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="441"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="658" mass="72982" checksum="15921477858C9279" modified="2024-05-29" version="1" fragment="single">MTNILEGGIWKGVPSLLAEGPVKMEDLKTLTSPIDILSPLIIRQLGDKLYDKRKQAALEVEKITRENRSKPAVLNKLLSTIINDFCYSTSPNSRNGGLIALAACAIALGNELIVNYLDLIIPPILSCFPDPDAKVRYYACESLYNVVKVAKANSLKFFNEMFEGLSKLATDSEISVTNGAELLDRLIKDIVCDQSTYYPPELVIGNLAATANISGLTEEQKKLIMDPNRKSSAIQLLQSLQPVPQAVSPIQQFGNSLTTTTSEQSENLEVKSSLPLPHNVKTVLVPGTTPLLPSMKPSTFNLPRFIPLLAERINVLNPACRMFFVQWILVLSSVPDLELLSYLPDFLDGLFSFLSDTNTDVRVATLTVLESFLKEIREVTELQRSRGCFNIHFAERPEVISKPNMAPVMSSSPTSTTLKYDLSSEELVNLKNKAAKKEEVGLKLETNDSEKESFVATTSSPSKDDEHPLSGDSDAAPKDTEKPLTVAPKDIPVTTSTKAIVENNNVQDTTDSLPPGINPSIPYVSGQGIRLDFGRMIEILIKNLNSDDEETQATSLKWISEFILISQEILIPYTNLILNSVLPTLSNNLQPIRSIAKEANLNLYSLISKNLNLNYFFTSEELEIIFLTLNKKLFDLNDETRLASLDWLLMLNKKNFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1M8</accession>
    <name>A0AAD5Y1M8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1M8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="534"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="753" mass="82784" checksum="DC708D9C0A6B3269" modified="2024-05-29" version="1">MTIRKKSKTLKLKSPPSSYLDKLEEPSKNNLKNLFNSKKTRKPTKKHFNFVSKLKTTIFNAIPILSWIQTYNIKKMLLGDFFGGLAVAFVAIPQTMAYASLAGLPPLYGLYSAILPPSIYCIFGGSKTLSVGLVAVNSLIMYSSISTLATPFSERYIQIALAASLISGIISIILGLIKFGSMITFISPGVLMGFVTASEAVITISQLEGLFGVTAEKSNISIIQCINTFKAFGALKWVALVNGIIVLAFLITLKYKKSKIPGPLVVAVVTTLASYFLQKTSYASLLPTVGFVPSGPPNFSVPQVSLADIPNLLTPALILCIIGFVQSYAIAQKYADIGDYEIDANQEFFALGVTKVCGSFFQAVDTPGSFARSNVNAEAGAKSQISSIIATLLILLAVMFLTPTLQYIPKSTLSGIVIIAVSGIFDITKYKKIYQVSVKDFTVSMLTAVVTFCTSMQIGIVMGIIFSIINILYNLARPHWAILGEINYAQKYTSNDSIGTTEASSSKNVTSNEVPDMIQTDSRSGGSVYKDLNRYKDALEINNVLIFRFDANIYFLNVSYWRSIIINLINDRIELSDDELGIKFDGMESNTKFFQKKKNSSCENVVTSGENILNEDAFNMERITIEDSEKKKLKFLILDFSPVDDLDYAGALGIVNTVRHVEEKYHTKILFASVKGALRDTFWKTVPGGIRSPRNSYYDLSESSISNSNVDNIDAVIADSNSKVENIKKPELINKNRFFLNVGYAVDYVRSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1P7</accession>
    <name>A0AAD5Y1P7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">H(+)-transporting V1 sector ATPase subunit H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VMA13</name>
        <name evidence="7" type="ORF">HK099_001798</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000155">
        <property type="protein sequence ID" value="KAJ3222874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1P7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RGS" evidence="6">
        <location>
            <begin position="47"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="658" mass="74598" checksum="57202611475F95D2" modified="2024-05-29" version="1">MATPRDAKSRVSLEGALNPTSKQQPGASGLPAPNAANTAKKVDLSAILGNLIPHPFSYNDFLEFLKKEHSVENIDYWEAGMKYRERALPLFPKPNKSKEIYSTDLTKAMTTSQTGSLKEDETESLTGNDGPQVDEALMLKQQLALKPDLDAIVSLYLTAGSQKEVNLPQNLIKKTIIEIHESKNYHPDVLKPTLEKTYEMIEHQQMSSSPPTPPSPSKASTEETNINSPIVASHQLYLAKMSSEIRARTIPWEGYQRASLISEEELAQIRQFENNPGVAFKESGEKYMYLFLTLLQKLVRTDTIQNILVLIDDILEGNGNRTSIFFNLAKEKNDEFLPFSPFIKLLRKDDEYIQLKSAKICINLFLKADPLPIFEPIDLYSWITSQLLNSNPNIVDISVQYLQSLLSITEYRIGFFKSPHAMTNLVDVLKKSTQAQMQYQTIYVLWLLTFVKEIAIDLQRSVKLEFPKLTPIRKYDVIPKMLEFAKHAIKEKVVRNIILKAPEENMIALLGNKALNVCEILSARKWADEEIIEDLNFLKTELSKSMASLSTFDEYSTEVKAGTLEWSPAHNSEAFWKQNASRMNERDYELLRILSRIISTSNNPTVLAVAAHDFGQYIKHYPSGKKIVQDIGAKKQIMELMAHSDSDVKYQALMAVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1T1</accession>
    <name>A0AAD5Y1T1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000088</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000100">
        <property type="protein sequence ID" value="KAJ3224227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1T1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1190">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045072">
        <property type="entry name" value="MKRN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224:SF10">
        <property type="entry name" value="IP09428P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224">
        <property type="entry name" value="MAKORIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="117" mass="13341" checksum="04488E182A0779A1" modified="2024-05-29" version="1">MIKSNTPCHFFLKGSCRNGAQCKFSHTNEIAQIQPQDVSAIPCRFFAKGNCLNGDRCKFSHSLNLPLSSFNNNPAKLVPVQLPQFKPLPNQDNDLPYQLDERDLELKDETDVMEKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1U6</accession>
    <name>A0AAD5Y1U6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cilia- and flagella-associated protein 44</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">WDR52</name>
        <name evidence="11" type="ORF">HK099_001438</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000140">
        <property type="protein sequence ID" value="KAJ3223187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885:SF3">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25828">
        <property type="entry name" value="CC_Cfap43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="5 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="580"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1447"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1503"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1586"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1750"/>
            <end position="1777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1453"/>
            <end position="1484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1794" mass="206107" checksum="1759D3DCCF8E635B" modified="2024-05-29" version="1">MSKSNLAEKQATSSIPDDFYYDAEKLKFYNLSFNEIEQEVLELHCSFGFDSHKRSNVHYLSDNCIVTSVGNLIVFLNLKSLEQEYYKALRNGGIGAIAIHPSRNYIAVAEVFDNSPLIYILEYPSMKVFRILRDGAIKGYSNISFNAGGNKLASVGQDPDFMLTIWDWKEEHIILRSKAFSQDVYRVAFANESDGVLTTSGTGHIKFWRMSSTFTGLKLQGYLGKFGASELTDICAFIQLPDGKVLSSTETGNLLLWDGGMIKCEISGKGRKPCHIGRIEVVLLVEGEIFTAAEDGYVRIWDLETIDNADVTTAYPGGAEKEKSDVASTSSSSNSRIFEMEPVDEILIGKDVKVKSMVRNPVNIDEYLIQDSLGHLFKLDTKKRTVEKLIVFHSGPIAGSDTSPKFHSMVTLGVDGTLRVFSYLEKRMIGKVQYPNEGSCIQYMPLLIDGGGSTVIAGFSDGIIRIITFGKYTVANGHEFMLQEVFKPHKSRITKIIISEDCEYFATVAEDKTVFFFNIQNLYKPELSFSTEMIDENYQPPYSKKLIKITPICFIETETPVNSISFSPDNHQNVNVLEDDGTESQQERMQESEDVEEDSDNNIGGRRLLMVLEDVGLMSMILPPTNSIDTSITYELSKDKFELIPWHFVVPDEKKKVESESIADEKVEEKVLGASEDREVKVVEEEKPELLIKENSPFQLVYYLEGGYFIGTIRNKKGKLMYTHIAAVTDLKLSSSGKYLLFGGADGTAGIRKFRVEDILLKDAENSPLAKQFPDSSGNGTISGEFWLGYAHDSSRGRIANLSNSFDDSFLVSVGADGGVVVWRNLMHEVKTVGKKLKNTMNFEILIFSDGQNEEFAKEETPDIDLEEDDEEEITISQERSKSKEEFKIEVVEDILDPNTYSIQEHKIKSEKDREIDEAEIKKQVTRNYIQDLRNEFLELLNQNEQVIPEWKLLRDSFSVDSDLRTDIEKETAEKIENLKKDQEWISEKESIGLHKTLKLDLSSLFSSNHDGTQEKLLQDVNDRNKTTDNQITKKLDSEEYKEQQGDLNGNKGQIKVLHDSRSKLEARKQLRAQRATLWKELIESKPDENYEDPRFENLICGKTNFSFFSDVANIRYAELHMGDYKLKTGEKYIVPESERVDADKKKRQLILLNESIFDLKENFNKQILHLRDNKQNLINKFYEYILKIETIDKKLVKMGETVEVLTTMPQMDPLAYPENRNLVTEEDIQYQLRLNEENAHTRTKEDFGGFANRLSAQKKEANAEITSAAADTELLLIQKPVDDSLKEVTSKSPLEILEYENTRTFLKYKKNRFLLTMEDALTKFDEKVENLVKEKILLDGDIKFADIKLLLLYREWALLKEFEKFDTTLADKLVTKKQEQDDIDQKIKECQDRLNIKKVEIEQVIKREKEIYSDFTKILGEGNKYEEFLTKILKRKIKRAKKKVKSEKVDGEEHEDESEEESDDEYGDGNDESDEEDQEEEICPNDCDTAVFNKVLELREKKLDEEEILSEIQKSIEALKKENESLIKKEKVIHVALKNTETEIQDFQTQKQKKLNELDVVVPLRLHQLYFLEKNALPADLSSALIFVEDGLRKLKNRIKELHQEKSDIKKNHKELKKMHISLKKSRKEKQLRLEDMEGRAYDVQMLKFGKVIDLEKLERMGVNKNAEELREKLLREDQKRLKELKLAEVQISLRKEKLTELIKDNTERLENKVSLTEQNKRLEDSLNTSQCSVTAEYNGPQKKDIIEKERLIKLVQLQSAEIEELKMEIELHIRKPVAPITSKRNAQENELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1Z0</accession>
    <name>A0AAD5Y1Z0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell morphogenesis protein PAG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TAO3_2</name>
        <name evidence="5" type="ORF">HK099_001101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000129">
        <property type="protein sequence ID" value="KAJ3223456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025614">
        <property type="entry name" value="Cell_morpho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025481">
        <property type="entry name" value="Cell_Morphogen_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039867">
        <property type="entry name" value="Furry/Tao3/Mor2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029473">
        <property type="entry name" value="MOR2-PAG1_mid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12295">
        <property type="entry name" value="FURRY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12295:SF30">
        <property type="entry name" value="PROTEIN FURRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14225">
        <property type="entry name" value="MOR2-PAG1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14228">
        <property type="entry name" value="MOR2-PAG1_mid"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14222">
        <property type="entry name" value="MOR2-PAG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cell morphogenesis protein N-terminal" evidence="2">
        <location>
            <begin position="87"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis central region" evidence="4">
        <location>
            <begin position="767"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis central region" evidence="4">
        <location>
            <begin position="1057"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis central region" evidence="4">
        <location>
            <begin position="1412"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="domain" description="Cell morphogenesis protein C-terminal" evidence="3">
        <location>
            <begin position="1616"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2407" mass="273150" checksum="74BBB7B81B6E5F64" modified="2024-05-29" version="1">MFADFGLEKIFPLLLEGEKPNIYQRDILTPSTSFNASNSAPTFSNIEGTRSENISSMVSSSSSFSSITNSATMTLTDEYSNFHNWKHLEDALFNPERLIVVLRAFLLLLADVENIFQKDGMVEAGSASLQVTTSRVLIEGKLNLATPPFPLSSWTVPPAVSNKVLPLSALEDLFNARIKSLNPVNPIPVAFQIPATKLSLNSYLSGSVIQRMGSGLREMLEKLNDVLGKAFFALDAQCGNSLVVDLSTPLSTTKEPTTSMIPTSGSYTEGSSLSGRRNSLSYPAGNSSQTSSASGNDLKFERIEKSEKDSFKEHQNLFDLLRTCIDCLPRLTPTNFSCGRLVELLSRYVLHVDKGIRSSATEALKRISNLNKNELDVNLTFSNGKKFWDFGDKELLSGSVVRIFAEVVGKIENEIFNDILVTLNHEGYENGCFANSAATYIDLLQILQVSVEREILIGKRWTNLEIKRIVEEIEGRGLICFLSQHFQSRKDGIKILNLARSIENVLNNNKMIERAEKDAKKEFNRRSRQFTTQTQQNSKKLKTKVVPNSSRIINIMELFGEELVRKNYLDPVFVSSSRSEQVKSQQQPRKKSSRVASEDALILMASSELQQDYCIFLRCIPELCGLIFEYGCSATVQLCLGSVLARIRILYPSVAYSAEQFSITTLGDRGKLLLNTTVKANSKPSNTVALTEEILDQWKIYSIFAAATVEITAANEIRRGNNTISLLDSKGLPLQEISEKLNSKEKKSEMSKPVLHAPSNLPTIISNSKHLIHILFPLLTCERQPIRQSSVIALTSMHWLSYQTFFEEIQPYFQYLSEDMRNRINSNKEIKGEQSSLLNSNTEKRKTFVLNNNSKKLERLRMELTNILGMIADFVNHDIYRKNDLFMSSIYVYTKTTKDFLSEADIQLEWDHQMLRYYYSCFLEKYYDRLIKSSQPGLTLDRFLPFHTRVELFALFEKWSGHGVQAAKTREREAKMMFQVLDHVKDIRERAVLTQTMEEQRKALEFASMKAMSSLLQGPVYNPKNTSASFNIALLLTWIDSIYFSLDESIHNIGDSALNSLLTFNSSDTHLIYQILDKCYSGTSDSVIARGYFLALVDFIVKKKSKVLIEPHKLICLGMYKVGDNMLSIRKAALELLHFFGKPHAENVFEISYEASAFGNSLPIIYKYSQILISTRLSIDKSEMTYEMLSEIVQRIEQVNSHVDSQNLSQIKDFLILIVPWIRNIELSTTGEREEFAVVLNADQQYIYSPLNSPRLGFVDIILNNLFYLTIQFGDVFVSEIESIWVKLLSFSDSDITLKREITDYEAQLIVEKNVEIVVEYLLNLGVKKRNPKLVMHAKKVIVYLSRTSSCRSLIDALVSRISPKTLVPNPVEEPKRYMNDTSTILSVNKSNLFTVDLSLILSDMPKRPPFSKGQLACVFLVDLTVEIGNEALKPHIPLLMNVIFVQLDHFIALICEQNRLLLVNLIQAVIPRDLAHEMIDGILLTLNSKEGRMWNYEDISPQTRQLKSTKELALLVQQIAELFSIIDPTFPQSWGETALNWGVSCPVRHVACRSLQILRSLSPVFTRQMLGEIFHRLSNTIADATEEIQGFALEILDTLDVMFDSLENHRVILFPQFFWACVACLNSPHEWEYFEAISILEKFLTVVDINDPSILSSILTSIPTKWLQKFDGLQVLLLRGLSSSICEEKCLFLINLLIVVENDQFVDKNPTKRLLHCVLANIPRLLHATESAALSETVLDCYTTAYNLSTICERLGQNNLAHLFKSYSKQKFRLKGDFISHAANGIRQGFFATHKEDILLFFTNLISNPIKYYKINAMRILKLMFPGSESIKSVDTKVGDKLLTPLFALLSTDLYPKSLEVLDEILKNSITAEESNLKLILGGKSIAKIIKEVENDTQNPTQDGAIKGYEQSGWKKVDFLLYSKMCRGNMVNVALLCSQKKSGKRGLGDKKDSIIVSIPINHNPNSELKNSVEDKDDDFTNELEKLDEMLKEENPTQFDLESSFNDYSSFITSIQHGFEIEPTILSPSTISRNENSVAEDTTQLLYPSIFKVEPSISEKLLSLPNANLTLCFKIGLPVQVMKEETEVSTSLKAALAEILNIEANSIIIHRVDADLDLNGNDITTESLVTIKFDELNASQTSRYVEKMSNIIREKQEVLKGVLSDIDLNWPPKIYIEIANLKIPLKKESQFLKFMDLDSPIKKIESNSNLDVSRICESFKLFPALFEMILNYYTEWIFLIGEFLKIHGTAETSGLRAIFECIKGLRIGTEMGYWPPLVATVDLQNDLLSVTKRYLKFKNLDDTFEEKFNLTKENYLLKMNFELKKFLFYQENYLSIFDIKNELCINLHYYLKSAGNFALSLIHLYKAVLELQGILESFLGLKEDNRNLEVENLDRCSIIIENFLAHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y203</accession>
    <name>A0AAD5Y203_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y203"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="16655" checksum="A6F35CAE7BA4E03C" modified="2024-05-29" version="1">MNSSKKSFSQPSSLQIQPTQPTLKKERSSVSPIRRSIVQPTVQGNGVNSRPASGGNSPYDRPSRTSTTSSKNSNQSDNDNESNKSYVSKYLFETQQIEKWTRNGQLNPGEVKVKIGDFVDGEMKEKLIWIFGVEIYNDALRVAKNAIANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y215</accession>
    <name>A0AAD5Y215_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000884</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000122">
        <property type="protein sequence ID" value="KAJ3223646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21678">
        <property type="entry name" value="SMP_TCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052455">
        <property type="entry name" value="Tricalbin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980:SF2">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="9">
        <location>
            <begin position="233"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="423"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="634"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="752"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1025"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1172"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1394"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="977"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1321"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="987"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1335"/>
            <end position="1351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3223646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1546" mass="174173" checksum="9FE94861F767CB67" modified="2024-05-29" version="1">MNEKDEFHDSLEKINEQGFKSNGPIPDDQSINSQKSNKEIAQKILSNLKKTHEKAEKPNRWGDIDDNDQKLEDISVGGLMAAKLAAKKFKNPELDNSLIESKAKAAKARETEKQKFTGFLFNPNFTDVLPQQLHSAYLKLSMEDVNLHNQIESLRPTIEILIYWENLTSTLVWSLSMCFVWFLARFNFSIVWLLIVVFYVGGSLKRNLHQLKNKIRRSVKDELSHLKMTGEDGREAVEWFNIFLSKYWVNYEPGLSSQIQESINYYLRLYKPTFLEDMLFTTFSLGSEAPRIEFIHTYPKTEDDIITMDWAINFTPFDEGEKIATSNRKSSKLELKLFVGKGGMTVAIPTVVKDVSLVGLMQVSIKFSSTFPHVKFVDICFKDIPEVTFNLRPLKGLDLMDMPGLNNSIHQMIKDQLKANVVDPVKIHLPLEEWAGAVASYDKPVGVLKVTVYQARSLKNRESIGLSDPYTKFIIGDKEIGRTHALNNTLNPNWGGSEHFIIIYESHLDPATDSDTLYFEIFDENETTKDKSMGRTNALKLSQWIKLAQSGPPTAKLNEGGDEDDEDEAIKEDAEEKKELLGGLTDAETTLLLKEWGSPFDATSELWKPLFMPGKEQKSIKGELKVNLVYFPVPKTDAVVVNEEEDDIESGIVTFTVHQVRDMAASLKAQNMSVVSELNTGEEIGRTNVIKKTATPVWDKSFDIFVKDVEGAKIKLKVLNNDHVTGFCLLDVSDILAKTNQSNDWYKLKGIPSGRVRVSIKFKPVDLEAENLTSSKPSSFMRICVREANDLKNVEMMSKSDPYCKVTLGNQHLGKTSTIEDNLNPVWKETFNVIAYTGTQVLAFSLFDFNGISKDKPIGRVSLRLDDLIDFNEIEKYLSEVLGTEVLEPTKSLLKSNVSLDDTSKAKDLLLKLQQDGLKIQSISPVFAEIWAPIYINKNKIKEIVKGKINFSIEVFPIVQNKVIKVDKKSRKKRKELMKQAGSLESVRADEGPDDTKVNESDTHPNIVVEEENVHKKTSKNSLIDLAEFERVKSIVDDFSAGIFQFKIHDAQDLDKNRNLYCVLQTAELKDPGVKITHGVSSSTYSTRIIQDSKTPSWNETCEIFVSNVKKNAVHLQLKYSHNEEKSNDDKTYAVWTGEGEKLLKTIGQANNWLTLEPTRITDLTSRIGNEVNPSVRVSVSYFPVYMEDETVSDDGELKLEILEASNLDALDRGGTSDPYIVVKCNSDQVFKTKTIKKTVNPKFNESCHVKVDSKKKANFKFEVYDHNTLQKHGLLGHFNLVLRSLPSNETVVKDFKLEGGGGYVKLQLFFKQKEDSSSHEKKSTTKKVLGLFGKNKEQKENKEDTEKEDTLSPLSSMDHGLSNKNSVLSIKDAASKQSQVGIGLPTSLSINSLSSRISSSHSVNEESNVIGEGIIKIVEARNLKAADSNGLSDPYIKIVQFYHGKMKQLHKTSVQKKTLSPTFNETFKCKVPLKFKILAKGFVDIGESSEIDIFDLLFPENTFESETSNPEVSKLTKKFDDWLPMGDGCGEVHLSGDFNLSILNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2Y3</accession>
    <name>A0AAD5Y2Y3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA damage-binding protein 1a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DDB1A_2</name>
        <name evidence="3" type="ORF">HK099_006744</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000060">
        <property type="protein sequence ID" value="KAJ3225471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2Y3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="1">
        <location>
            <begin position="22"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="2">
        <location>
            <begin position="439"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="730" mass="82326" checksum="93BA8D29F365CA25" modified="2024-05-29" version="1">MLLQSSSVLASVPLIFKGETLLLIGTTSKLTIKKIFNSQSKEITSCEVNARIATIQTIKHDNDNDFIFLTTEKYQVAILALRNKEENQEEDTEYFFETVYTDSIRENIGRPVDCGQLLTKVAEDLFCLHLYQGLLLFIPTNIYKGKVSKSRTPNTKFRQRYINKHPVTLILFNRIEELNVISMASFTSFHNLKSKQQKKLKIALLCVDSKEKKFIKIYSINMELLCIESDAMFDVEADSNFLIPANFESNGDDNNSGFFIVGECQIIYYKRDGEWLTYRFLKSTIYKCFTPINRISLLLGDFDGNLMLLTVKNKKIVMEHLGKTSMANSLAYLDNGIVFLGSHFGDSKLLKLLEDAEDTMQLDSCDNNSEVEKNYILELETYENLSPIVDFVVVDLLKRGQSQMVACCGGYKSASLKVIGQGLGIDELISMDELTFGSLGMWSLRQSFDSDVDDAIVFSFYEETRMIAYISESILGEIKNLGDFDYNKCTVNCGNVNFNLIVQVTSNSVLLLTNKTKGFKKIDEFITENEKEILFASIIFNQVLIGLTGGELIYFKISKSSLKIISRKEMHQDISCLSLGDGVVNGDSNNRNICAVGYWDCTVCLYSLPDFECVDKEHLPNDVISRSIMIKTFDDVDYILVAQGDGNLNFLQITKENNVVKGFVKYMSSTYLGLEPVTLFNLKSVDVKTKKLADGVLVASDRPTIINASNGKFLYSSVNLKVIQILPTKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y303</accession>
    <name>A0AAD5Y303_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LD-carboxypeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004511</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y303"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07062">
        <property type="entry name" value="Peptidase_S66_mccF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="entry name" value="LD-carboxypeptidase A C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237:SF6">
        <property type="entry name" value="CARBOXYPEPTIDASE YOCD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="MURAMOYLTETRAPEPTIDE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="LD-carboxypeptidase A C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LD-carboxypeptidase N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="LD-carboxypeptidase C-terminal" evidence="4">
        <location>
            <begin position="200"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="36835" checksum="CE02EAD62B1583D4" modified="2024-05-29" version="1">MLIPPRLKAGDEIRVIAPSNSAFIISAATREEATRKLNNLGLKVTFSKNFEEKDEFNSSSVTTRLNALHDAFADQNVGGILTVKGGFNSNQLLKKIDYNLVRRNAKIFCGYSDITALSNAIYKKCNFQTYIGPHYSTFGIKKDFDYILDHFVKFCFHNTNKLLITPSTFWSNDAWYLDQENRKFIKNEGYSILNHGSAIGTLIGGNLNTLVNLNGTEFMPDFDNAIMCLEVTVENTPQNFDAMLVSLILQPNFEQVKGILIGRFEKASEISLHLLRLIISSKEELNNIPVICGLDFGHTEPQLTIPLGGTCEIVANVDDLKIYFSNEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3Q3</accession>
    <name>A0AAD5Y3Q3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pericentrin/AKAP-450 centrosomal targeting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003146</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019528">
        <property type="entry name" value="PACT_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF40">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10495">
        <property type="entry name" value="PACT_coil_coil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pericentrin/AKAP-450 centrosomal targeting" evidence="8">
        <location>
            <begin position="2497"/>
            <end position="2571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2711"/>
            <end position="2738"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="118"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="370"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="519"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="680"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="872"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1227"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1448"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1567"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1964"/>
            <end position="1998"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2058"/>
            <end position="2099"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2126"/>
            <end position="2178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2212"/>
            <end position="2250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2356"/>
            <end position="2425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2601"/>
            <end position="2628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2711"/>
            <end position="2724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2738" mass="317029" checksum="ADD30170D1B85300" modified="2024-05-29" version="1">MSSPSARADKLAQAKRKLQKFQQKRNINPLTHSSSNPDIQEQVIQQLNTDTNDIPPSSLSSLNDTHVNDLVNSNPIISKVRNFDDDTASIASSFAVTPNNENIPKSDEKCIEDLNILNNKLSKENILLLEKIKLLENEKLIFTAEKESILKQNENLDNSLKDYKKQLEKLSDIQEAKTNLQEERSAAVDIKDFELLESDLKRISSEKENLQLELNQKIDLLENTDTYLHKVEDAFNEVAKKLTGDSALSLVISDELNFENSLKLIKEKIFEADEYNKSEILNLKTQLDQINIQVKENENYLNHTERILEENESLFQVQCKEFREQIEEKKAKIQVLQKSLTFAENSVDSTHLKNSILELEQKYTQSLEINSSLNERITEYETKLQESVAAVEELKNQNDLVKSEFASKIKDLEEKISEATSSLTEKCNEIVLLNEQIQTLITQNSVDNPSTFADHRAIIHENNAKEIAELRKAHSSLSEDYELLKITYEKNVEKIISTTTKSTTTTTYYSETSDEGHYEAISEDHNESLKNEIKELKLQLEALQLRSPTDDTKFQLRVHIEELENSLETSKIEIINLTKERNQLNENIEELLEKVDDLSQKYENTNRSFQNLFENSGEQIESLVKENSQHLLKIKSLEKLVQENVPSSEANGEDLFQGGGDWDLDFDIITPMNTPSSVIIEQYESKISELTQSTANLTSNLSETKSKLSQLETLQNTLVEKYDSEVKALKALNAEEKLKLENDFKQKEEQLKKETSKIEDLLESNGGLEDQLTTLELNFSLLEKEKVKNIKNFEEKIKILEESFNLEKNQLKESYENTIVTLTDQLNAVTFQLKDSIAETESKSFSLQQELGEACDARDDLASKLTIISQEYQKLNAYCSELQEKNDEIQLRLEELSGALTSTTSKETELITELEEKNVELLSLQEKVKALEENQIKTSNDMAVLVESFQEEMSPILVEKERLLKELSESTDALSEKGQEINMMEEKLKLLEDKLDESNLLIKKKDEKIIVIEKEILEIRNEKETIMKNLHDLNAELEEAKCKKNEVESLVQSNEEYIQSLGFELEKYKKNNQNANESALNEIKTLTLKISELTAVNEKNYDVMETQRLELREAREHVVNLEKEAQILEAEREELIFQNQKVFEKEKAFELNIKDYEFRLVECDEALGLLKRELDDERELLRIEKVNMAELTKQWQNEISDQKLKENKLVAQLRECSLEKEVALKNVAAISEKLSALIEERDSLEELKNTLENENWSLEEKNIQMNDKLKEAELTVKKFKDSYENLAAENITNFESAKKLRDELVQFEQEKTLLHETLKTLNSKIVELESDKEDLYVKIEEEKFLHEKLALEKEDLLSKINQIQETVGESIELKKQFDNILNEKTKILDEKEALAKSISSLNEELNKVQQKQLTHTSKLAAEISSLKEEIEFNNATIKIRDETIQELQELLSNEKKQNLQNFEELNEKNQLKISELESSIKSLQDARVEAYNKVEEVQKELALKIENLKESTSLYNNAMDDIEVLSKDLRDVTMEIEKLKSINLEQESKISEIDELYFKLDDLSSLADERLSQLEKSRNEAVKFEEENKRLVEEIENLKASIGNLVNVDKENKELKNEIENHILRNEEFTMNIANLSNELKSIKESRATIADQKVNGGVAQGTPTPNIPKESEEDIHYNKIVLENEKLSKELKYERDNNTALKLDIHTLVKTLEKLEREGLVNRNSAQHLAYGNSSEEDEKKNESLVKALRRELEFKDSEISKLYSEFESKLRIAEEKFAEFSKVGEKAISNTQYLQSRTVLGSESADKIGSFKYCCGHPDCHKNCLDNEEKMYNEEDNLSHLIEVFISTITEYQQDIADFMYKQETLLDSLKAGRFKSSRAIQEEIRLQSDHFIDIQLQYESLQKQITYVCSNTKRGEFVSQSGNYSFDSNERTPHQNNSSVLPEIRLSSEEYMDLTSRSSQANHLRIQFDNAQNLITELNKEIHVLKSAIETMTQTSHRKTGPVPEDIARMLLNKQIEELRKVWSHELSANNILRNLIAKTQKDSVGNSEEQSRREADLKEEIDELVSIIESTSKENKIYKQKIAEKEKKLNEVTKNSESKFSSSFLEYQENTSALDEIHHSEVEALSSLVKTLENERDSLISDFKLAKARFEEKLNFVSNELKRSQSQNEKIKSTVEGETVFLRKELKDVKLEKLAEQSRLQEAATKKSLEYERKLKDIEEILRERENNFNTEKKNLLERISELESRESLNYKQQGSFTDLEMLRKRDAERRLADREISWDVERRGLFEEIDRLKDAARADASALRYIRSQNENLEKLLVQRDFKIKKLESSTYVFPPYGSERSHSVDGSLRFQELERELQSCSQKNRTLLEEINKSDMARHQLENQIRVERDRSNRYSFKIEELQRQIYEIEQNYGREQRIDDEHLHNEITILKKELKKVQQHNQDITIILNETISSIIGETNEYKYQLDVSQFKIRAGQVIQEVIYLRALVNRLALQRADLQYQKIYLSLQVADLLSSQKVTLTYIKGMGISTQSVGGDLTIRKKFIRCVNVVITITRLRRLAKNWKDILQNNGRDLSDYLNIGNSSVTRNNIEAMEQNERLVLMLESEVGNLRAEKKEIQDMLVLTQSQKRILEAENLRLSKLPNVFEQEGKFEQEKKKVNERILKSSVGMNGNEKKGIKERVANTLNVMKESTLKDFKEFSNINEPTTNNDLVSSINEGLKNTIPPPTHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSH2</accession>
    <name>A0AAD5TSH2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WLM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002175">
        <property type="protein sequence ID" value="KAJ3199163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSH2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47795:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47795">
        <property type="entry name" value="UBIQUITIN AND WLM DOMAIN-CONTAINING METALLOPROTEASE SPCC1442.07C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WLM" evidence="1">
        <location>
            <begin position="44"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="202" mass="23678" checksum="AB29DA8B720AA6B8" modified="2024-05-29" version="1" fragment="single">LLIGTNEDDLKVVEKKNQTRSTLFNLTSVKPFSDPINRYNKYKFNAFEVLQEFSDNNKALNYLEKLSVDKGILAIMKKHEWSVGLLKEIHPLRESDILGYNLNKTLPRSDHDEKFHNLNKILDKEVYDLDWTQTKGYKISNEEFFTFSDEQDYKNLLDKPNIIDRHGMESKNLSTKEFILNSAASNADNIEKLRDARLKKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSU3</accession>
    <name>A0AAD5TSU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001907">
        <property type="protein sequence ID" value="KAJ3200431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSU3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="342" mass="39852" checksum="702A982D22718B57" modified="2024-05-29" version="1">MSKHLTLCEYSINKPLITSQSSKTPSTNLLLSSQQEIFEFQNQCLPPSPPPSPITFFPFQTTPNFCLQKLPLTFEKFCLRISLLHEKYLSQHFQMSQRNSCIVALNSIYWRVFFNNNSLEVKIPEELKQLQVAQTNFGLNLVNADIYLNKLKVLSVTFNPYMENSCLDGFRILNSTNLLSLHLTSNLNFMYNLAIFKNCGIWDTPMRTFLNTVVTEFSNLIKSALFLEEAIFQDKPVENKLNCTNATKYLHLKIPIDKYNEIDFILRKKSLRYLLKELSKDVDEIVRDITRRDEFRNVCTNLCCFGALCCDSNTISDFKIDWQEDISDNYFIDLIIFLRLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT03</accession>
    <name>A0AAD5TT03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001841">
        <property type="protein sequence ID" value="KAJ3200759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT03"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="54"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3200759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="250" mass="28289" checksum="C7311F7263140C9A" modified="2024-05-29" version="1">MTYISVPYPPSAVAKGIISLQDNMARLATFQSQMETLSTALRKPMAVAAAENYKWYHLAVWGISLVVALIPFAVQDYNAKGAIYADAGIWCWIGTKYNNYQVSLLYGPMWAVFVYTIFAYTYVGIKIVQARKFVMKSGSGKASQSSINRFAFKAFLYCIVFLFSWVPGTFNRASAIIDDNPMHTVYEFFLVQTIVMPLHGFMNSLIFFFFALTGNMPETSNSGSKNGYSSRDNSRSRSRSRKDEEYQNYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT71</accession>
    <name>A0AAD5TT71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001664">
        <property type="protein sequence ID" value="KAJ3201840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT71"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="637"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3201840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="672" mass="75868" checksum="9518638E1992E91E" modified="2024-05-29" version="1" fragment="single">MENVDSNLEEDLQQLLSQVDNAGNFISDTMETDFFQTQFQDSPHSKEKQNIQIKTKPNYNLTDQSDILYQTETISQLCDDFSNNYDDSKFNLTNHNENANSTRDDCHPILQTEFSYFHQIQRPEILQQGDFNEKGDIDNLTTMEKKDLKKNSISSSSPICQTVNLVHPTPIPLSINTKILEFEQPYQTPSRTSSVNSSMKNYTTDSTFHQQTSAGIVNSPFSHFSIHSPVSQNSTSSPYPQTTANSPLSLISCSSFQKSSLIGTAHYPQGLNNQQILSPFPTPNQHQTFEFPLNKVNYNANYPETNRKSYLSNEVTSQQINFNNSMCSNPELQQQNFDLSTNNPPLVVPLTSQHPNFNNYYSNLNNQEKNLISPVLSPFSSGTSSPAHFDFPQTIYHSSNSQLSQLSHSADMLETSNHKINSVAMNIPDATNSAAGSEDCNIIINSQHPSNNRGFDQNNTLNFITKEKNKNFGINNYNNNSPSTQNFNFGNGGMYNYEKIKKNNTELELITDENDQQQFDQDSSEVKKLSDLDFTRNINKKRQLYLPTTPAPQQIKLFSKVNIIEEVANVGGGGGKGSKSTSKKKSTTIDTSKIAKRVEFRDGKEVFCCAFFDCIEEFSNEYLLASHQIKHTQIKCFGCTKCEKKFGRHHDALRHVKNVHKISPNDAKVYTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUD8</accession>
    <name>A0AAD5TUD8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000772</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001198">
        <property type="protein sequence ID" value="KAJ3205508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUD8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000795">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1130:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.190:FF:000003">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="65"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3205508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="357" mass="40624" checksum="539AC42FD44319B4" modified="2024-05-29" version="1">MCQKKFLFENKIVDCNGKDDDQAFEVEDSSLVDKENEVVTVKFNKSQDPSKLQCRMYENKFPEVEDLVMVNVRQIAEVGAYVTLMEYNNIEGLILLSELSRRRIRSIQKLIRVGRNEVVVVLRVDKEKGYIDLSKRRVSAEDIQKCEDKFNKSKTVHSIMRFVAEKQNLDLEELYAAFCWPLYKKYGHAFDAFKLALTEPKKLFDFLPTNEILTEEVKRELLNSIKKRMTPQAIKIRADIECNCFGYEGIDAVKTALFAGEACSTAETVIKIKLVAPPLYVMTTSSLEKNSGIKCLEDAITIIEQTIKKLGGSLTVKMKPRAVSESDDLELAQLMAKVGRENAEVSADEEEEDEGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUU2</accession>
    <name>A0AAD5TUU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001055">
        <property type="protein sequence ID" value="KAJ3207424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUU2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="160" mass="18470" checksum="F17B41052286A8C4" modified="2024-05-29" version="1" fragment="single">IVMLDTKNFVETPPLMRVHVEHKALVGLTTTKGSFPKYAINDYADSKGFSASQCRLNHVNDTRNVEWWGKEKLEKLSSNQKESYTDPLVKDFKSLILTGGTNHTENWETFRKKKQFNNSVHSYNIVTGSKETTPAMKVIRRINFAKLDSKNCDSNFERFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUW5</accession>
    <name>A0AAD5TUW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="10">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GPH1</name>
        <name evidence="12" type="ORF">HK099_000608</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010001147">
        <property type="protein sequence ID" value="KAJ3206150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04300">
        <property type="entry name" value="GT35_Glycogen_Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000002">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000003">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468:SF3">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE, LIVER FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="710"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3206150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="843" mass="95453" checksum="1945802AE17D43F7" modified="2024-05-29" version="1" fragment="single">KSSSTLTKTSVVAGSAHGGNPHPTHSQGSKSLVSPVLAANPNQSLFLDARKPSVTNRIRTVTGPPAHELGRVWKATPEAMEIWKKHIMTCPKDKWNATQQYHTSKDPKRVYYLSLEFLLGRTLDNAMLNLGVKEVYKSALEKLGFTLDDLISEETDAALGNGGLGRLAACYMDSLASTNYPAWGYGIRYQYGIFQQRIQDGYQTEYPDYWLNFGNPWEIQRLDINYDVRFRGYVTQNVDADGNTNYSWEGGEKVVAVAYDYPIPGFNTNNCINIRLWSSKPQKEFDFASFNEGNYDKSVEEQKNAENITSVLYPNDNHMVGKILRLKQQYFFVCATLQDIVRRFKKSDRPWSDFPKQVAIQLNDTHPTLGIAELQRILVDEENLSWDEAWHIVTNTYSFTNHTVLPEALERWSVPLISDLLPRHMMIIFDINLFFLQKVEKAYPGDREILRRISIIEEGHPQYVRMAFLAAAASHTVNGVAALHSMLIKTEIFKDFVNFFGEKKFTNVTNGITPRRWLHQANPLLSDLITQTLGSKVWLNDLTKLSELKKYAKDSTFQKKWMEIKYQNKVRLAELIKTKCGISVSPDALFDIQCKRLHEYKRQFMNILYVIHKYQYLKSLPPAALKDVVPRVVIFAGKSAPGYYIAKLIIKLINNVADVINEDEDTSEYLKLVFIPNYNVSVDEIMIPASDISQHISTAGTEASGTSNMKFVLNGGLILGTVDGANIEICEEIGDDNIWLFGALAHEVEDIRHDHTYHKVVMDSNLQNVIEDIRQGGYGDAGIFEPLLATLTSGHDFYIISKDFPASAGMGNFSSDRSIIEYAEKIWKIKPIPVPDGAAADIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV01</accession>
    <name>A0AAD5TV01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Non-histone chromosomal protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NHP6</name>
        <name evidence="7" type="ORF">HK099_000131</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the NHP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001012">
        <property type="protein sequence ID" value="KAJ3208112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV01"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01390">
        <property type="entry name" value="HMG-box_NHP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000016">
        <property type="entry name" value="FACT complex subunit SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="20"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="20"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3208112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="100" mass="11485" checksum="A51FD9545EFA7C42" modified="2024-05-29" version="1">MPKDEKKKRVVKRKKDPNAPKKNLSAFMFFSQSQRPIIKAEKPDAGFGELGKLLGEAWRNLPEEEKAVYQEKADKDKVRYAEAAASYKGQQEQDVVDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV68</accession>
    <name>A0AAD5TV68_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000967">
        <property type="protein sequence ID" value="KAJ3208960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV68"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3208960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="210" mass="23564" checksum="5A1B486F04DCDF94" modified="2024-05-29" version="1">MDETGNTLNSLNKVDHQPDLIIEVKPNGCTTSNPNISTPISMPTTPKDSSENNNYFSKDDDSPNYTLLLTDNSNFYGCSICNLKFLTFEALQYHNKSAHNNNNTNLIDDKKNFNDTNNHNVQQAESYLHHASPPDSASDTSSTCREYTCPVCQHKYHTAAGLRYHTKAIHKMTPKVANGEVPKPATFKCQHCEKKYTSLGGLKYHLKVNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVE7</accession>
    <name>A0AAD5TVE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008386</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000913">
        <property type="protein sequence ID" value="KAJ3209995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVE7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF434">
        <property type="entry name" value="GB|AAD18119.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="240"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3209995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="32055" checksum="76B84183661D2CA1" modified="2024-05-29" version="1" fragment="single">MNSNSSFYSNPSLGQFSSQQIWAPWKAVAITLAIFLGIVIVVCVSAYLYLFKYFDEDEDREDEESRHFVEFPSLPPHARLSKLEISKFRTSVFNKKRPIKYKPPRKEKMRSMRKNKSVSFTLELNSLPNLNLNFNENKISSPVRLNFSENKITSPSQYNENKVSPGHLNSNENKMVNSLQLDSTLNNQFFNFSFNIPCFLEKFHEIKFDEASKKSRFSHRFSSSDYNSRRSSLVSSTDACIICLEDFEDGAEVRHLPCGHFYHSMCIDEWLFKKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVJ9</accession>
    <name>A0AAD5TVJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxiredoxin-like 2A</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Redox-regulatory protein FAM213A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008228</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxiredoxin-like PRXL2 family. PRXL2A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000888">
        <property type="protein sequence ID" value="KAJ3210482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVJ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630:SF31">
        <property type="entry name" value="PEROXIREDOXIN-LIKE 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3210482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="264" mass="30269" checksum="B8A1E4BDFE40D78C" modified="2024-05-29" version="1">MKDQAVCLQYEAKNCNSQNGPGNFIDKVELLNLRTQLPTISSTLWSKNELFKGTLILIIRRPGCAICRDEAALLASKRSLIESKFKIKMVCVIHQLEGHEELVRDYWKGDCYLDSGRGFYKALGNGTYNMARAITTLSNPIVWKRWRNAKSKGVKDSYSGEGRILGGLFIISSKGVHYSYVERLSSPPPMEEILTTCENIYNTFEEEKLKEEVHTFESESNMEKNKREFRKDSATETEILLDYYFDSHFCLKDDGGYLDKKPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWB3</accession>
    <name>A0AAD5TWB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008179</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="4">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000873">
        <property type="protein sequence ID" value="KAJ3210791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWB3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002270">
        <property type="entry name" value="PRK01202.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="GLYCINE CLEAVAGE SYSTEM H PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715:SF3">
        <property type="entry name" value="GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="14"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3210791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="118" mass="13180" checksum="65C13F3187EB7379" modified="2024-05-29" version="1" fragment="single">FTNDHEWVLVKDEIATIGITDYAQNSLGDVVYLETPTVGKSYSQSEIMGAVESVKAASDIYAPISGEVTEVNTKLNEEPSLVNTSPYENGWIAKLKINKPEELEKLLNKEDYKKLIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWC3</accession>
    <name>A0AAD5TWC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000857">
        <property type="protein sequence ID" value="KAJ3211072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWC3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="106" mass="11492" checksum="31F43EC3BE48E027" modified="2024-05-29" version="1" fragment="single">LQPQVHFVDDKSSIYTSSSSLHPSISTSTRAIFAPSILQQQPIYLKESSNVASAGSLSRNREKVSSVFSGKEGALNERDPELKSVHTALSFGDKSIETFSIWSCAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWM0</accession>
    <name>A0AAD5TWM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001109">
        <property type="protein sequence ID" value="KAJ3206655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWM0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3206655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="143" mass="16447" checksum="B2F00DE7F49902D5" modified="2024-05-29" version="1" fragment="single">MTPNLVVATCLYLATKIEESPHHIKSVVSEMKSALKHSGGFCFEAQDIAEFEYYLLEDLNFNTILFHPYRSLLKFTKSLQLEEKITEEAWAITNDTYNSDLLLNFAPHLIALASLKIAIVVNKKHESITVKKWFQNINVDWSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWT1</accession>
    <name>A0AAD5TWT1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001077">
        <property type="protein sequence ID" value="KAJ3207139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWT1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="113" mass="13002" checksum="80EF743D96848073" modified="2024-05-29" version="1">MIVVRDWIEKHKEDLQKNDFDCAYMRSVMPISEVCFLLKRVLTNKTASFWRGVFTELRSRQVEVSLSDGKFEFAGELSGFEIQSKIASLTDLSKYRVLYGGRGIILTLESLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWV0</accession>
    <name>A0AAD5TWV0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000731">
        <property type="protein sequence ID" value="KAJ3213250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWV0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="521" mass="60047" checksum="C9AA69BA58E23C42" modified="2024-05-29" version="1" fragment="single">MKKGYKKEKKKLVEKKEESFEDLLEEAINLEEKGDRFGAGEKSRRFYERSCELYSILDTMKNKNTEVLYNWGRLLQILSEFQNPSYSEEEKNHLISESIAKFRTVYEIDQYDHNNLFNLAQALRVKAELSTGAVSNPIPKNELSPNAKNSDESTPLYEEAYSILLNVFNLQFNEYQKLQNSQPNEDSVMMEQDGNVAEEEYVDENEKNVTLETLAETLLVQIQILYTHAGNLAKRSPSEAEKLYQTAFSKLEEAKGIFNQAINVPIAEEKNNYNNIFPELEHTWANVFWSRGETILEIIEKDKINSVNVSAEELNSNYNELLFSLENSLSKLELVLTHEPKLVEAICDKADVLITLGDAKQSLSNSALVSAEISEQLKKECRLHYAASTKLFSEAHQLEKSNRTILLKLGDIHLTRMQFYIHDKKILKTLSNGACIYYRLVLNLLHSEEKDLKILLGFRILKCLSYGGEEKLEEFLTVLSKFQFFLGELGINGKNFIYDENEMEFNLDFCDDVKGLPEYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWX4</accession>
    <name>A0AAD5TWX4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">acyl-CoA oxidase</fullName>
            <ecNumber evidence="6">1.3.3.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">POX1</name>
        <name evidence="21" type="ORF">HK099_000267</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; peroxisomal fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heteropentamer composed of five different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.6" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010001054">
        <property type="protein sequence ID" value="KAJ3207437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWX4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000018">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000013">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000015">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF352">
        <property type="entry name" value="ACYL-COENZYME A OXIDASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="19">
        <location>
            <begin position="105"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="18">
        <location>
            <begin position="226"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="20">
        <location>
            <begin position="365"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="17">
        <location>
            <begin position="592"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="536"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00063271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3207437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="785" mass="88144" checksum="40AD3D26F9D71D81" modified="2024-05-29" version="1" fragment="single">NTKNRLKKLKNRMMKIKTKKYFSSGVWLNDSKIPTFDTEEEDDESKLVIGEEEIGVVVSRVERVECRIVVGDDRIVVMSVVVAAVVVKSVVVATAVVKSVVVATVRELTYLLDGGKQNTELRENIMLSLQRDPVFDISDYHDLDLQTIREKTMQKVRRMAFYLSQEPVPVSHVRMQLLSLLDPGAWTRVGVHYGLFFNTVRGQATPEQFGYWVAKGAIALNGVTGCFAMTELGHGSNVAGLETTATYDEASDEFIIHTPTLTATKWWIGGAAQTANHAVVFAQLIVKGKKFGVKSFVVQLRDKDFRLLPGVVIGDIGAKMGRHGTDNGWIQFTYLRIPRSHMLMKHTKVHRDGTVIEPPLQQLAYGALINGRVSMVVDSGNVSKKALTVALRYAAVRRQFGGSENEPETKLLDYIIHQHRLIPLVAQTFAMHFTGVEVNSIYEDLMTEMECLRPGDANAKAVLENLRDVHGTSAGLKAFCTWMCLKIIDECRQSLGGHGYSAYTGLSSLYSDFAVQCTWCDIIYITLVIIDFKNREGDNTILTLQAGRYLIGCYRDSKKGIKQPKGVSYLNNLAGSLNKISNAKASEEIASLESLGEAFDFVVANVVKNAGEHFETLKAKGLSDEQAYEECSSSRLLAAKLHSYGYLFHRFKDAVKKTIQPDLKSILEKLCLLYGLHTIQENSGSFLEYKYFNSTQIDWVRERVTFYCKLLRKDCIILTDSWNLSDHIINSPLGRFDGNVYEHYFNLVKKHHQPGAIPSYFNKEILPMLNRSLVQEDPLEIDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX51</accession>
    <name>A0AAD5TX51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000606</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001145">
        <property type="protein sequence ID" value="KAJ3206166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX51"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20335">
        <property type="entry name" value="BRcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="708"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="370"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="402"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="286"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3206166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="848" mass="93507" checksum="1D489107A61C442F" modified="2024-05-29" version="1">MNASISIPSLQINDSNDEMFSDFKEANSNLLSLQRPYSPSHSPISSPSNSLNYFPNSPLLSTSFNNPPFSTLPINSQMDDLDLADDLENFLFNDNDSRRASNISASVPLITTSSDDFLFNTPDYNNNINFSNSNLGISNLNVASHNIDIRRKSTSDLKSENPFGSSTSPQSSFNDFGFANLPLSKSIENVNQFPLLQENHTFNLSDYDPITSDIKLEITGVSQQQNQHLNNNNGHQSHEFDLDLLLASYPNFNINNVPISPTLSTSNFPVSPTLSVTNIPLLAEQQGLPDTSPQDFSNLFSGFNTSNSNNDDTLPGASNANNNNLSINSNAGSKDLLSPQSTSGPLRRRKSRSGTTSPTGEKTEKLEATHQCPVPDCNKLFTRRGNMMAHLRTHDPNRERNFICQICQKSFCRPHDLQRHSSVHTGIKAFHCPICQKSFTRRDAIRSVTGGYSAEYLAKLKLSNFSWAIAGRNLKKLQTVKQELVKINPANEEIVKILVHENNFESLSELVKKTEVIISTVGPFAKHGETLVKACVEHGTHYIDSTGESNFIKTIIDKYHKTAKEKKVYIIPSCGFDSVPSDLGAFLIAHHFNSKYNEQTKSAYLSVKKIKGAASGGTIHSALGILELSGAERKSTMSRNCLVDGEVPPTDSESLTTTLLHYNKLLKSWQSFYFMEFPNIRYVARSNSLLKNAYGENFKYGEGFSHSWLIRGILMNLIIFFAGSLLVIPPVRSFVKWMVPQGSGPTRQEVATGHFVMSVVGESEKNKKCLLTIKGVSDPGYGETCKMVVESALCIALVNSSLPKEVATGSNFPNIEGGVVTAASALGLVLVERLRKAHMTFDLKEISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX67</accession>
    <name>A0AAD5TX67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001013</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001260">
        <property type="protein sequence ID" value="KAJ3204838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX67"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408:SF58">
        <property type="entry name" value="TRANSCRIPTION FACTOR (TFIIIA), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3204838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="247" mass="28078" checksum="1A2B1294E1DC2B06" modified="2024-05-29" version="1">MFNKSLSVEEFLNMENTTKSLTNFNSTQQQLNLHSTQSNNNSNVTIISPFFTKAQPIQMKSCSKYNTSPSFSTLSSSLESTTSYFSTSSLISPPYSPGPTELLLSQKNLNNRFNLAEDLFDTDIDEDVLEFDLIFKNGLNIARCDSVSSQISLDSLPDIIVPSTPPNLSNNCSKEDSLKCLLCNYTFQRKHDLKRHHRTKHLNIRPHKCEHCNKGFGRRDALERHTDVPAPYKCKALYDGRKRRKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXR7</accession>
    <name>A0AAD5TXR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001747">
        <property type="protein sequence ID" value="KAJ3201312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXR7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="515"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3201312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="582" mass="65537" checksum="4FBC23198B0D215F" modified="2024-05-29" version="1" fragment="single">MGNPSPLYPATNDALHYSEQHLLNLHKNHFHALSQLTDQLLNNHRYASTSCNSLDVDTNIQNSPPNNNSTSSNSSPPNNNSTSSNSSPPKSSNIPKELFLNFNNDSNQVSNLEFDLLSNNEDENINSMNFQQISSKVKPLPFDHPHNQELENYIENEIAPKTPITPNFLLPELVLKNNNNSNNQNNHNSLNSPVVLNSPILPLNANQIPFSKPFGGNTLNQFQLNQQQHHNNHLQNSQFLNIKHQNNGILPFNEKPTVFKRFNQQTNKRKSNFSHPNLSIKIPKTSINNALLNSPRLNSPFHPAVFSPNTPLTTCAVYSPSIVGTPLTCSPLEPNSFRSPVLNSLGFFQQIQSPLTPTPQISNSQRHQQQESIKKNNNVNSKTDSSPKQIFIPQYHINNSNQLSYQCIIQSEAQFNQAEIDSNSQRINLIKNQNENFKLPQSAAVLFPTPPASVDEAKTENLPPKQKNFVTHLISENLSENLPDSQEERIALLLQPVFQAVTDPSTGIEVQRRSFDCACGKQFEKLCGMKSHLKVHQHHKETLSFNETLNKLEWINIETGQKIEILNKVDNNRSHICKDCGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXX5</accession>
    <name>A0AAD5TXX5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-methylacyl-CoA racemase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoA-transferase III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000926">
        <property type="protein sequence ID" value="KAJ3209724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXX5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008111">
        <property type="term" value="F:alpha-methylacyl-CoA racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008206">
        <property type="term" value="P:bile acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="entry name" value="Crotonobetainyl-coa:carnitine coa-transferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="entry name" value="formyl-coa transferase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050509">
        <property type="entry name" value="CoA-transferase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228:SF5">
        <property type="entry name" value="ALPHA-METHYLACYL-COA RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48228">
        <property type="entry name" value="SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="CoA-transferase family III (CaiB/BaiF)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="42458" checksum="C44F7F349C06D737" modified="2024-05-29" version="1">MPLTGIKVLEFAGLAPGPFAGMILADFGAQVIRCDKIATSTSDVLARGKKSISINLKSQNLINVLKKKIIPKVDVVIDPYRPGVMEKLGLGPEILLKINPRLIYARITGFGQEGYYSKVLGRKNENPMFPANLLADFAGGGLICALGIVLALFERVKSNKGQIIDAAMIDGVSYISSFIFKMKQNGLWNNPKGENALDSGAPFYETYKTKDGKYIAVGAIEPQFYTILLNKLDLKDLPDQLDMMEWPKLKSIFAKKFLEKTRREWEIIFDGTDACVTPILEIGEKNIGSDIMLNKHNKDRNFLSKSEDADDMFEPLPAPRLSRTPSKFFEGSKKVTAAEFTRQPKVGEDTFSIFLSFGISKSECDALSEEGAIFDSSLSLDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYI2</accession>
    <name>A0AAD5TYI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="13">Aconitase</shortName>
            <ecNumber evidence="13">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ACO1_2</name>
        <name evidence="17" type="ORF">HK099_008650</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000978">
        <property type="protein sequence ID" value="KAJ3208766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYI2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01584">
        <property type="entry name" value="AcnA_Mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000002">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000003">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000004">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1060.10:FF:000001">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF3">
        <property type="entry name" value="ACONITATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0408">Iron</keyword>
    <keyword evidence="9 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="15">
        <location>
            <begin position="64"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="16">
        <location>
            <begin position="581"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="515"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3208766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="778" mass="84414" checksum="B54EAE3052E420AC" modified="2024-05-29" version="1">MLLKKICSTINCSNAKISKRAFASVSDKVTMSPLESDKFINYKRIEDNLKIIRNRLNHPLTLAEKIVYGHLEDAKNQDIVRGTSYLRLHPDRVACQDATAQMALLQFMSAGLPTVAVPTTVHCDHLIEAQYGNDKDLPRAKELNKEVYDFLASCSAKYGIGFWKPGSGIIHQIILENYAFPGGLMIGTDSHTPNAGGLGMVAIGVGGADAVDVMANIPWELKCPKVIGVKLTGKLSGWTSAKDVILKVAGILTVKGGTGAIVEYFGPGVESLSCTGMATICNMGAEIGATTSLFPYNKRMADYLNATKRSNIASLANSFKHNLVPDEGAKYDSVIEVDLNTLEPHINGPFTPDLATPLSKFKDAAKTNNWPEELKVGLIGSCTNSSYEDMTRSASLAKQALDAGLVAKSKFTITPGSEQVRATIERDGITEIFDKIGGVTLANACGPCIGQWDRQDIKKGDKNSIINSYNRNFTGRNDANPATHSFVSSPEIVTAMIFAGSLHFNPITDSLTTPDGKLFKFQPPRGDELPQRGYDPGQNTYQAPPADRSSISVSVDPKSNRLELLKPFKPWDGKDAKEIDILIKVKGKCTTDHISMAGPWLKYRGHLDNISNNMLIGGINVANDKANSIFNPLNGKFEAVPKTARDLKAAGRPWIVVGDENYGEGSSREHAALEVRHLGGFAVVVKSFARIHETNLKKQGMLPLTFDNPKDYDLIDPTDKVSIIGLTTFQPGKPLTLRAHKKDGKTVDIKVNHTFNEGQIAWFKAGSALNLMAAAANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYM3</accession>
    <name>A0AAD5TYM3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000722">
        <property type="protein sequence ID" value="KAJ3213329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYM3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040807">
        <property type="entry name" value="DUF5522"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21037">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21037:SF2">
        <property type="entry name" value="SIMILAR TO NOVEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17653">
        <property type="entry name" value="DUF5522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="87" mass="9940" checksum="C05EFFF544BA617C" modified="2024-05-29" version="1">MSSEKVKHTDTSTPYYLVHKAACEKGGLTYEDPETGYTVFTELSHLKRGKCCGNKCRHCPFDHVNVRENKSKTFKVEIELEKSNSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ55</accession>
    <name>A0AAD5TZ55_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005684</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000454">
        <property type="protein sequence ID" value="KAJ3216910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ55"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF11">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1075"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1118"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1158"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="56"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="204"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="352"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="509"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="11">
        <location>
            <begin position="752"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3216910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1258" mass="143260" checksum="AB7DC80D2200748E" modified="2024-05-29" version="1">MDPKLSSKYTSLDRNLRLKKLKSASSVGNLNHSDLKIDSPFFKTEQNLQLLSKFSLLKNSSITDLEFLIENSQLLYFEDGKSILKKGQVGRTMFLVLQGNVECSDSSVGTQQIISENSYFGEIGVLFSVPRTCDCIAKGKCTLLGITKGALKLIAPVFPELKEDLIFKSQQRFSFYVLNSNIRNINIKLDDSLQIVSDTKNTHLIREYEVGFLNILIIGKKTEKFKKGDILVAKGDCLEQIYFILNGKACIFFEDNKTVYQELKPGKFFGAFYFSNKALATVGVISDSIEVIKLTKKNIDYVLNLFPEMDVAIKTEAKRRYNNFTTNKFNESNLNDKMSLSTVRETLKNVPMFKSASTSFLDEMATKLQFLQFQKAETIVKMNSTGNCMYFLISGSAEFISEDKKTTFAVINAPSFFGEVSLLYGVKRTATVRAQSEGCSVLELSKSALITVLNSHPEIAKKVNEISKENHRLYQSRTTSLIQSRSKLGDQIEIYGLESTVERVKKVPMFSKCDLGFLRFVALSTSVRFAEIGDYIIKIGQLSTEMYFIVRGTVEVVSQDGNIVFDTIAEGGFFGEIGVITGAVRTASIRVSSNKCDLISLSRISLDKIFKCSYESYQKIVDEAQNRMQTICRRRNLSSGIKRDEKLNLLKIFKKFKRSKVLPTEKFDENLLRADTITNINGNEELRSSVTTIRNDTPTEEKVYFENTNAVKLFFKHIRKSSSAHSNSSVNTSVLKSFTFPPKSLPRLKVKRAGLFRLERECFEIIMRMLDLKDKINLLAVSKDFNELLKGENFWLELKFDKLSRRMTMNTLIKYCNKVSTDLEKLDLTGCYFINDSSVNSITDICPNLSSLNLSNCWNISDTSIKKIGLLKRLRELDISYCNKITGHAFETVVWAEISSLNISYLKNIRDEQLDRFLCTTTGLKSLFMRRCVNLTDFGLLSVVRYCKTLQDLDLKDCSQISGKCISTNLKSLNLTFCSKLSNISSKDIMLDGARLVELNLSFCTGLNEEEITNFLKNGSQNLKFLNLRGTRITDNFVYCFMQYNKGLKKLDLSQTNISWNAIQHCLSLNTNINIIFELGLGLLLLIVIKNLTLTSSNNDTNHWNIKKISNLSVRLKVFRFFWILMFILTIFIFSKFYSDFTLQVSTLTFNKQNKSEINTMLWDVGCLAISFESLLVIEYMNLITSLTKLTLRRFQETIPITTEFISEIKNSGYTFEHSTKKLNTSELDTVIENFRRYENLKGRRNSVPLASNFAHHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZK8</accession>
    <name>A0AAD5TZK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UBC4_1</name>
        <name evidence="6" type="ORF">HK099_006832</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000613">
        <property type="protein sequence ID" value="KAJ3214531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZK8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000002">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3214531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="110" mass="12464" checksum="A6E1E0A63E012A66" modified="2024-05-29" version="1">MGPSDSPYSGGVYFLSIHFPTDYPFKPPKVSFTTRIYHPNINANGSICLDILKDQWSPALTISKVLLSICSMLTDPNPDDPLVPEIAHVYKSDRPRYEATAREWTRKYAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZQ2</accession>
    <name>A0AAD5TZQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcriptional activator HAP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HAP2_2</name>
        <name evidence="7" type="ORF">HK099_005166</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000391">
        <property type="protein sequence ID" value="KAJ3218207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZQ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12632">
        <property type="entry name" value="TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3218207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="204" mass="23635" checksum="354FDA9F47C6F16D" modified="2024-05-29" version="1">MEQNNNLNHNLQKNAQTAPEISQLLLNSPAFQQVVNMYKNIIIQNSQQITQQFDNNPNTALQQNAFTNPHINATNLPFHANINLNVNNTPPIPFVSADTTNQYITDLARPPVFVNAKQYHRIIKRRESRKKWMELFKLKQTPNEKNYLHESRHKHAMTRPRGKGGRFLNKEDVIDNEEAEESGISKENQDNCNQLELLIEPKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZZ0</accession>
    <name>A0AAD5TZZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000549">
        <property type="protein sequence ID" value="KAJ3215378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZZ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="107" mass="12197" checksum="9B20BE2F938DD3C2" modified="2024-05-29" version="1">MSGKMLNDCFKTQSESKCLEKGSSADDLSEKPNSRNQVHSVQTVLEKKWTPVMMIIAYEVVLGKPAPVWLMHLHTAGPSFSCLCNPILVYFFDIQMRNTLKCLVFWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0P1</accession>
    <name>A0AAD5U0P1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004447</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000313">
        <property type="protein sequence ID" value="KAJ3220141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0P1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000770">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050467">
        <property type="entry name" value="LRFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45842:SF12">
        <property type="entry name" value="KEKKON 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45842">
        <property type="entry name" value="SYNAPTIC ADHESION-LIKE MOLECULE SALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042128960" evidence="5">
        <location>
            <begin position="27"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="349" mass="39888" checksum="EA1DC7B836666665" modified="2024-05-29" version="1">MRIIFRKIYFFKLFLISLSILKLVLAECISELTDEQSDIPSYIRTAASCDEDGNVIELWLKYQNLKKFPVGIGQNFSKLQHLYLGGNYIETINFEDFQNFENLTTLDLSKNMISYVEKGTFDSLSTLVTLDLSRNKISDIKEVTFDSLTSLVTLDLSQNSISKIESGAFNQLPFLNELDLSFNQITAITDSAFSGLQTLKILMLQFNQLSAIYEGTFKGLQQLQKLNLANNKLNAIDEFSFQSLTALLNLQLTSNKIQNIENVFHINLKKTVEELWENLEGNSLEQIFENTFEDLKNLTELELSINKISSIESNSFQNLHNLEDLNLGYNLIKELKNNTFYGLQNLANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U166</accession>
    <name>A0AAD5U166_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Dicer-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_003811</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000255">
        <property type="protein sequence ID" value="KAJ3221055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="331"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="11">
        <location>
            <begin position="532"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="8">
        <location>
            <begin position="1024"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="8">
        <location>
            <begin position="1266"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1139"/>
            <end position="1160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1568" mass="179589" checksum="C4D3FB963E70D1BA" modified="2024-05-29" version="1">MEEVKREVARAYQLELLEHAKKMNVIAVLKTGAGKVINQQADYLRYNSDLNVTEAYGALGVDSWEKSKWENIFDESDVLVMTPQVLVNIIHSAMITFHSISLIVFDECHHTRKGHPYNQLMEVYRHFNGEKPKIFGMTASPICSNEDALNSIRTLEKNLECKAFSVDISHSGQQQNYLAKPKEEIIFYELGPFFRLPALYKKFIQHGGTSIPLVNKKLKDVLTDCDELGTWWADRHMEILYGELRNFSSRKNFEKIWSEREDGEIDSGDEIIIKDELEQKELTEFISRLIKDVEKNLVCKVESNFGKRKRKEVDLDLFPIPTITEADISPKLKCLFDLLEGYEYDSTFSGMIFVETRRSSVILKTAFLYHPKLSKFLRPQKLVGHGNQDSINFSMLSTEQEIVVKKFRDNVYNILIATRIGEEGIDIQSCMLVVRFDQFRSVINYIQSRGRARHQESKYICMLPKGDVEKLRIYKEILAKEVAMNKALLESAAEDSRDADDEEDGNNTPYLLKPEEIFTIPSTQAIVTIFSAISVLHRYCAMLPIEEFCSSVPKFRFILVGDVRNDSQQCKCVIRLPFSVPPDCRVFEGPPCDSKRKAKQYACFLAIKNLYEAGELDGHFRPIQVEIAEAVKVIPQKTKQASSKVRKFNAGLAECLKGSWEDKEEFYLSIIKIKLTENAKLPTYKYTQSPVKLENKVLNVGVLTSNRIQKEGENEYFFELPIREEGGHLGVALINDEKKILVSKKKLSNIKTFHTKCLNFFLKALMKVEADWAYLIAPIKFVNDSPVLDELTLDLVMDNFDQNLFSTVFEDYQKKIGVFVKEMKEKTNAGDEIGYNTTVAVMQPPSPPDFEHPYEKSFLQIMEDPNFDLEFHKENTILVDHYYYGRKYMIVDVLDIKPGDPFPMELLNPEETLAKNYFKKFATLERFYKGRLRCFEKIKQNQKILRVIQVPQFCQPDRLKTHYCETNTTIEYLDFPFVKYCKSPAALYIIPQFSRLFFVKKPVLLNDIIYLPLILRTMEHSLNCRDIHERLNLHFIPRLLLQQALTTPAAQLPFDYERLEVIGDSFMKLLISLHLFASNPTHLEGRLAIARSSLEGNRLFTKKAVKIGLYKAMLTTPLTRLLWAPAVRQWTHVEYELITTNSQPPDNGANKDTESNDVEESIQKDISEAADGVANVPSIGKPILSDVSHQRASQVTVIGDKTIADGVEALVGAGYISKGIRFGVKAANNLLDSNYEENWANYAEIFKKQGYFSENETKSKKYLESIKKVEQLLGYTFKHKHLVLEALTHPSAVEDEEFTTCYQRLEFLGDAVLHFLTTRFIYIKYPLLSPGTLSSYRSTLVCNKFLSCVCGVLGIQKYIRHYSPSFTKPMVDFGKLLEERYEIYKHLMGKPEDGLNYDSSKDVFPNRGTVPFWDDFDDTPKAIADVFEALLGAVFVDSLDVEEEKEFSLDTIMTILNNTMLIPWLPLVGPPCGIVNHPVKQFMDSCHQLLHCRAIDINAKRNYDGTYCCEVSLHETVICKADAESKKSSRRAAAIMGLDYLKKHALELRNSCTCTGGAKKDVDIIVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1R2</accession>
    <name>A0AAD5U1R2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase family 49 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000492">
        <property type="protein sequence ID" value="KAJ3216195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1R2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="42042" checksum="417408BE2C964822" modified="2024-05-29" version="1" fragment="single">MTVAISKKTLTTRKYGGNSVESFPQPHHTTWEGLEAEEQREPLSNDQLSEVTEVDQLSDTNHKNSLSPYTDTFVFDKLFSNVLKPSKLQPFYYRSKGVTKNDDITVTSLITVDRFDILLNNMLTYEGPFSVALHILDDNKLNSHLSKLNNFLEKYSNITEYRLDLHLIIDKYPRQFNYFRNVARFFSKTELVLPLDIDFIINKNFLKHFAKNEKLKEKLKNEKAVFILPAFEFTKDLVDTKYLDFPQTKEEITHLFGENFIVFHGNSNEGHTSTKYDKWFQSNEMYTIQPFSTKYEPYAVFNSSQVPWSDERFTGYGANKAAWWYEIYLAGLEFWILPDDFVIHQYHKYNDAVRHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U209</accession>
    <name>A0AAD5U209_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Signal recognition particle subunit SRP68</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Signal recognition particle 68 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SRP68</name>
        <name evidence="16" type="ORF">HK099_004744</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SRP68 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000344">
        <property type="protein sequence ID" value="KAJ3219321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U209"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15481">
        <property type="entry name" value="SRP68-RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3450.40:FF:000001">
        <property type="entry name" value="Signal recognition particle subunit SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.40">
        <property type="entry name" value="Signal recognition particle, SRP68 subunit, RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007758">
        <property type="entry name" value="Nucleoporin_NSP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026258">
        <property type="entry name" value="SRP68"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034652">
        <property type="entry name" value="SRP68-RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038253">
        <property type="entry name" value="SRP68_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05064">
        <property type="entry name" value="Nsp1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16969">
        <property type="entry name" value="SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Nucleoporin NSP1-like C-terminal" evidence="15">
        <location>
            <begin position="871"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="570"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="662"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="799"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="845"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1089"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="95"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="939"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="996"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="570"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="611"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="662"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="680"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="799"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="845"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="859"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1092"/>
            <end position="1110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00083741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF05064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3219321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1110" mass="121968" checksum="BD7841732B923C99" modified="2024-05-29" version="1">MEYSILKITNETRNMHGLRHNDYERYRQFCSGKIKRLRKSVNLKQMAGKKYAKNEITVDMDLTANHLSILLFQTERNWSYAMQLKVESQEHPRKRHQLIRKLEKAKQNSAVLENLIKKNSGLVDDLSNLEIKAYSALMHGYLLFERQDWEKALDKFTTSKAIYEKLSHVTTSKQHQALCFAVLDSNEPNIRYCAYKLGNSLDVSSLLELKKAKGFGLEFISSEVDSVLAKNRNKNFKAKRFRDNELPIKNEKLLDKILETEQAEVQLDSKLKNSPDSLKFDVNKKFDFELAEKILEIYDSVLGLYWDCNKISESDIKEDELATKKVSSSKSEENTNNLKLIHCFVSYSRLSRTIERNLLLIEITKAKLGTQNSKEKKGPKSEDVIKLFDTVLKSLNEINDISCLENDPTIKNIISIKILLYKAIRCHFVAKSYSELNKTEEAQLLLEKTKEYITKGKSLLLSTSNRGSNALLDTDVEELKNLKYGFEDFEKVLFTSIIEEKVLKFLKKDEKRNARLDSLFGTQPAGSTLFGGFSSTPATTSSGFSFSANPTAQTAPSAFGSFGQNTGFGTPAATAQSAPTSFGFGSTPSTQTTTPAATSFGFGSTQATTPAASSFGFGSTPSTQTSTPAASSFGFGSTSSTQAATKATPSFGFGSTPSGQAATSFNFGSTPSNQTGTQPASNTSNTTATTASTKPATLGFGTPATAAGKLAVNSQFFYFILLATTTQATSFPQFGANTGSGGFSFGATPATTASTTLSTTKSDGFVFSTPAVPGSSVSQPAATTEGSLFSTPATTKSVNFSLSSSTPTTDNKLVAKDTPGPLNLSDLGTPHKPTFGAPFTTSAPATTALATPSTPATHGKSSGSNVKATGTLPLKNKTMQDILNKWTNDLETNTREFHKLAEDIKHWDRILLENGYLISNLFNEISTVEKFQVEIESELEYIESEQQELDLNLKNYEEKVREIYQANLQATTDTNQGTTFKMTPVDEEREKNYLVAENINKQLDDMGKQLKNLIEDINLSKNENKVKGSGEGMLDEGDDTPIDYIVKILGQHLSSLEWLDQSTTQLLDTVKEVDAQALTVKEVAERVHKTVPSRSGSGENSNMRNSFQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U248</accession>
    <name>A0AAD5U248_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000209">
        <property type="protein sequence ID" value="KAJ3221779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U248"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042154084" evidence="2">
        <location>
            <begin position="22"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="850"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="903"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="903"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="936"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="967" mass="102252" checksum="E30E0B83634982F8" modified="2024-05-29" version="1">MKFSALFLVGLSLIQTSTSLALPEPKTDRGNAGPNQHGHSCHWYEKNNLPSPSHCADSQNASNDRGDAGPNGHGHSCHWYEKNNLPLPPKCTSTTTSCTKTDDASTATATETAVETTESSETTTTESSETTTEISATTTESSETTAESSETTAESSATTTESSETTSESSETTFQVTVTETVADTSSSEATTSAETTNADSSETTAAESAESTTTFEVSATTDDTFTFVTSFAPTGNAFLPFTGFGSISAPTELPAGFSGSNESSSSSSESSSSESSSSESSNSESSNSESSNSESSNSESSNSGSSNNNAVTVTVYETVTKCASGSGNSEFTAVANAGEVSAVNGFAALAENGEESTNVPTGVEASQTEIAIEATAAATGAEGTNVFTILQATATVLESENTNVVTIFDSTETSVETVSVTQTEVATTTIFESSPATETVVSENGHEHEHNHEHNHEHNHEHNRNRAQWRHNRYRKNRLGAVLIVNFVASAAIVPNLSKRQDGPSHNRHNRFRLDRNGDINGVHNHESGGHNHRHRHIHDHRNSHDHRNSHKHHHHNEHSHEHNHKHHHKHSHKNTNEDSEDCSSDEEVSTTTATETTTVSTFSSSFSSFSSFSSASSFSSSDSFTSTVFNVAEPTQTVTETQNVIIGFVNDAAIGQAPTNIAQIPSGLAVTDTTKTVTLQSTITKSASEPSFVPSGAIDDFFLPFPEDTDAPNLNVVLISTSSSTTEAGPTPEVSTNLVFMITEDFTTADATTTKDFTIADATTTKDFTTADGTTTIDSATESTTILTVITTSTTESSNDVFTLIATVTVTATETETETETETKTGTGTVTVIKTVEGERPTTTVFNTFTTTVDRTPSRTDAGDDEEHPRGTTGPNGHGHSCHWYEHHNLPAPKKCNFSPSVDGSTATVEQPEISSTSDATTTENSTVFETGDSSTSSGFSSFSSSKSSSSFSSSETCFGVGCFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2K6</accession>
    <name>A0AAD5U2K6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004243</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000296">
        <property type="protein sequence ID" value="KAJ3220505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2K6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="8"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="261" mass="29411" checksum="B63021F2EB43C494" modified="2024-05-29" version="1">MKIDPAPREDQVYMAKLAEQAERYDEMVAFMKEVAKLGVELTVEERNLLSVAYKNVIGARRASWRIVSSIEQKEENKGNEGQVSKIKSYRNKIESELGDVCSDILLVLDDHLIPAAEAGESKVFYYKMKGDYHRYLAEFAMGDKRKEAAGFAHDAYKAATDIAQTELAPTHPIRLGLALNFSVFYYEILNSPDRACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTTDLQDAEGEKAEEGKAPEEGEEVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Q9</accession>
    <name>A0AAD5U2Q9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA topoisomerase</fullName>
            <ecNumber evidence="9">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">TOP3A</name>
        <name evidence="14" type="ORF">HK099_006224</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000523">
        <property type="protein sequence ID" value="KAJ3215748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Q9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031422">
        <property type="term" value="C:RecQ family helicase-topoisomerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.290.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF21">
        <property type="entry name" value="DNA TOPOISOMERASE 3-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Topo IA-type catalytic" evidence="13">
        <location>
            <begin position="1"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="GRF-type" evidence="12">
        <location>
            <begin position="491"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="GRF-type" evidence="12">
        <location>
            <begin position="583"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="GRF-type" evidence="12">
        <location>
            <begin position="662"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="11">
        <location>
            <begin position="719"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="419"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="738"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="467"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="744"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3215748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="770" mass="87141" checksum="AE58D4CF0A4A9CA1" modified="2024-05-29" version="1">MELDLRIGASFTRMQTLKLQSNFDMLKDKVLSFGFVVDQYKKVENFVPEEFWYISVSLNKDEIHTKFSWTKNHLFDQQICLVFYERCVENPSAKVETVSSKPKEKWRPLPLTTVELQKNASTKLRLSSDRVMSIAETLYNKGYLSYPRTETDIFEADFDLQSLISIQCQSLQWGDYARSLQQGKFRTPRKGQHNDKSHPPIHPTKSSEGLADEEFSVFEFVARRFLACCSENAKGQETVVTIRIADETFVATERNYLDIYKYEKWNGNNIPIFREGEVFSPTSLTMENGSTTRPSLLSESELINLMDKSGIGTDATIHEHIKKILDREYAVKDSSRCFLPTILGVSLITAYDEMDIDLSLAKPYLRSFMEGNMKLVCENRISKDEMIRHTINLYKNAFIVASEQSFLFKKHFAKLLEENQNQENEVNSTTRKRKPRTNANSHTNQRNDDDEDDDGHDRPGRGGNGVVNAQNTRKTKTNLQSANNAENIPICDCGNIAVQRTVKKPGPTFGKLFFKCSQNVGFGCNFFKLVDTAIPSNNNFVLPSHNDRTINKFQARSVMTTTERPLNGIDYQPNIWSSTAILCQCGVPAALRKVKKEGPTFGRDFFGCRNGKDFGGCDFFKWADEPDINNNNPFKAFSKNNYQQPRTLQHQNTSFNESKATCKCGLIAKVNTAKQGENKGRNFVSCVKSTGRCGFFEWVDKNESSNLNISATAAENFICYKCGMPGHFSNNCDKASSISGRGSLKVRGKSKTRGTTKGRGRGNGKPKLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U310</accession>
    <name>A0AAD5U310_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000367">
        <property type="protein sequence ID" value="KAJ3218717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U310"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042094212" evidence="2">
        <location>
            <begin position="23"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="327" mass="35515" checksum="C4F92D2811DC96F9" modified="2024-05-29" version="1">MKFTAIIALTLSASAIAHKAKATSTPCETNEVQPTKAATTPCETDEVKPTKATTTPCETDEVKPAKATTTPCETDEVEPTKATTTPCETNDVEPTKATTTPCETNDVEPTKATTTPCETNDVEPTKATTTPCETNEVKPTKVTTTPCETDNVKPTYVAKPEKGYPSKNLKPEAENKPSYGGYPTKALKPDSESKPSYGGKPRKALKPERSGKPSYGSSNVLPNHETKGYPKQDLEPLKDFKPSYGYPTQSALPEKEKAYPTQAIKPTHKHKCKHHKAKPTYASETLPESEYKPAYQTIAPAADLKPAYGYPKQAIEPETEVKPNYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3C5</accession>
    <name>A0AAD5U3C5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bystin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000146">
        <property type="protein sequence ID" value="KAJ3223057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3C5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007955">
        <property type="entry name" value="Bystin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821:SF0">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05291">
        <property type="entry name" value="Bystin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="49527" checksum="956B2C844C281FC8" modified="2024-05-29" version="1">MPKITKRSGNGGSTAELNRIKLGPFMSEESVKKKKELKQKKNQQSTESNFVDSKTTRKILNLVKDQQNEVLEEVNGTVNVLENYGFNGNQGSPRESDIEEEIYEDDNDLEIDDLDLDAKEMEILEKFMNKEPKKQLNLSNLLLEKLNKNKEQSLKEQIDTQDKNFGLNEKVVEVYTKVGLLLSRYRSGKLPKTFKIIPSLENWEQILSLTTPEKWTPHATYQATRVFTSNLKAHLATNFFKMVLLERVREDISENKNLNYHLYMSLKKALYKPAAFYKGIIVPLCESGDCTLREAVIIGSVITKVSIPMLHSAAALMKIAEMEYTGANSLFIRVLLDKKYALPYKVIDALVFHFLRLRDDPRGPMPVLWHQSLLVFAQRYKEDMTREQKDSLIDLCKYQIHPAITAEVRRELVGGVERDHKEVKSMDMTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U443</accession>
    <name>A0AAD5U443_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002797</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000196">
        <property type="protein sequence ID" value="KAJ3222016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U443"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="103" mass="12057" checksum="5E05A48B44881E12" modified="2024-05-29" version="1">MSRNRVFSEFNHNHNFKTTPYTPDEFMSQNDDHAGRLSNKLGILKEISLTIGEEVRYHNKMLQETDDTFTKTKDYLGATMNKLKILSKSENDKLRRNFSGKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U462</accession>
    <name>A0AAD5U462_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">26S proteasome regulatory subunit RPN2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RPN2</name>
        <name evidence="10" type="ORF">HK099_000879</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the proteasome subunit S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000122">
        <property type="protein sequence ID" value="KAJ3223641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U462"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000017">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016642">
        <property type="entry name" value="26S_Psome_Rpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048570">
        <property type="entry name" value="PSMD1_RPN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040623">
        <property type="entry name" value="RPN2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18004">
        <property type="entry name" value="RPN2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21505">
        <property type="entry name" value="RPN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015947">
        <property type="entry name" value="26S_Psome_Rpn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="9">
        <location>
            <begin position="5"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN2 C-terminal" evidence="8">
        <location>
            <begin position="759"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="809"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="894"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="817"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="898"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3223641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="938" mass="102485" checksum="3E56EF9A74AE6B8E" modified="2024-05-29" version="1">MVNLTSAAGLVALLHEDNAEIQIYALQSLLQQVDLFWPEISEAVTKIEELYEDELFKQRQLAALLASKIYYHLGEYDESLSFALGAESLFDISKSSEFVDTIIAKGIDKYISLRRQQMDQSQTSAVVIDKRIEQVVEKMFTRCFNDKEYKQAIGIALESFRLDVVENAINQVKDTTEKIKILKWVLTTVLEIVQNLEFRNKVLRLLANFYHTQTEPDYDSVCQCYIHLNDFAACAELLKSLVEKDEFHKLVAYQLAFDLEENATQEFLSKVLGSLPASQIQAVTSTAADSDAMEVDNNETQPLLSESNKNISPQDSAFNKIRKIISGESALESKNSVYHNAITFANAFMNCGTTSDEFLRQNLEWLSRATHWTKFSATAALGVIHKGQIEKGKDLLSPYLPKDGVSGSAYCEGGALFALGLVNANHGAGVVEYLVKSLKDATDETVQAGACLGLGVAGMATDDDDVYESLKNVLFSDSAVAGESAGLAMGLVMLGTASAKAVDEMIQYAHETQHEKIIRGLAVGISMIMYGREVEADVLIEQLSLDKDPVLRYGGIYTVAMAYSGTGSNKAIRRLLHVAVSDVSDDVRRAAVTAIGFVLFRTPKQVPKVVQLLSESYNPHVRYGAALALGISCAGTGFKDALDLLDPMIKDPVDFVRQGALIAMAMILIQHNEVLTPKVKEVRKLYETVIGDKHGEVMAKFGAVLGQGLIDAGGRNVTVSLNSRNGHNSMPSIVGMALFTQYWYWYPLTHFLSLSFQPTGLIGLNGNLEIPKFTCTSNAKPSLFAYPPPTKVKEVEVVEKVATAVLSTTAKAKSRQKKSDKEKGAVDMDVKKAPKKKEESSETLENLARICPLQAQYVTFDKDARYVPVKKGAVEGIILMNDRTPNEPVELISSSQPANAVEATSATSTVTATPASAGTVSAAGNEPAPPAPFEYTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4C7</accession>
    <name>A0AAD5U4C7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Angiotensin-converting enzyme</fullName>
            <ecNumber evidence="12">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_000598</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the peptidase M2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000114">
        <property type="protein sequence ID" value="KAJ3223878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4C7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008241">
        <property type="term" value="F:peptidyl-dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06461">
        <property type="entry name" value="M2_ACE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001548">
        <property type="entry name" value="Peptidase_M2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10514">
        <property type="entry name" value="ANGIOTENSIN-CONVERTING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10514:SF27">
        <property type="entry name" value="ANGIOTENSIN-CONVERTING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01401">
        <property type="entry name" value="Peptidase_M2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00791">
        <property type="entry name" value="PEPDIPTASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52011">
        <property type="entry name" value="PEPTIDASE_M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 6 12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0732">Signal</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042129576" description="Angiotensin-converting enzyme" evidence="13">
        <location>
            <begin position="17"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor 1" evidence="5">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor 2" evidence="7">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor 1" evidence="5">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor 2" evidence="7">
        <location>
            <position position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>chloride</name>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>chloride</name>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="6">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601548-10"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601548-11"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601548-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601548-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601548-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601548-8"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3223878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="561" mass="64268" checksum="33A013DB830FCDC9" modified="2024-05-29" version="1" fragment="single">MKHFYILSGILIAVSAYTKQIPFLNAQTSERKFPDARSFLNHVNKVFSDSEFEINQASWNYNTNITEHNQKVSTDIEIKANEVLLKIIEEAKQYEGETEDEKRQLLLISLKSGTPSSREDQRRLSELQAKMTEIYSTAKVDGHTLEPDLTETLATSRDYDTLLKAYIGFRDATGPKIKPMYEEFIKLMNVGAKENNFDDAGALWRAGYDMGDLDFVTMMEKVWQQVLPLYEQIHCYTKYKLSEKYEKVDENKEFIPAHLLGNMWSQDFSNIYSDILIPFPDVTPVEITPELVKQKLLSAWDFGNNDLRIKMCTAVTGEELLTIHHEQGHLYYDHYYSNQPSLYRESAADFFHEAIGDTMVLSVVVPEHLQEIGLLKGKLEKSLKQTINAQMAVALSKIAVLPWAYMVDLYRWKLFAGVVTKENYQSEWENLMKKYQGIERPIPGVSTDFDAGAKYHVPANTPYVRYFGAAVIQFQFHESLCKVAGHTGPLHECSIYKNLEAGNNFKNLLSLGRSKTWQEAVNIGTNGQYDTLDGQSLIKYFAPLMDWLKEENKGKTCGWGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4E0</accession>
    <name>A0AAD5U4E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000369">
        <property type="protein sequence ID" value="KAJ3218673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4E0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF8">
        <property type="entry name" value="LEUCINE RICH REPEAT CONTAINING 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="345"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="436"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="746"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="413"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3218673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1044" mass="122555" checksum="E6D307B9BA7F0DE4" modified="2024-05-29" version="1">METVVLINKSLKSVQEVLDEKNLNQREASKVKYLNLHSNSFASFNNFNLFYNLINLNLSSNKIKNINVLLNFPILEVLNLSNNEISQICNLDELKNLKNLDLSFNRIRSFNGLHNIKNKSNLIYLNLKCNILKNDISEVNFLKGFKNLKHLVLQSSHTKKLINDSTFMSKNQKFNPLLENPRLYSELNSIGLQNINLDDSFEIGDINRDTYENLLINEKEIFFFKNLPNKYESNEVKADLSENEDNFPSQKNVNTKNEQKKSKSEKIASKIPVSKQKLDETLPLNNEPIQGAELSQPLHSQLYLESVIDRLLFMKKEEDTKNEKAALLAELKMLKEEKEATENKYVNFVSSDENDEKGSEPSVSRNKENRSNFVGAKKIHRNDTFRNTKSGGKINRPKLHTKKSTISTKENISTSFNDSSSSTTSSRIQHQNLLNNSILISALEKEEKRLKEVEVELRSQLKEVEVQLSNKNAHYEKLNENLATNIKNVKLEKLYFKEKEISELKKKEREVLELEFSQCQKNYAAYKDKVAELEKHNHELKSNCEMLKNYEKLKDAEIQHLRKSACDAEIGLANFEGKLKMFEDEKARLSVRFVKDRELYKIKLAEEIEIYRISLKQLKQDLGISKKHLKESTGTLKEEIEKLIFKHKEELQEVKLQSFNEKCKFDKVEKEFLNHMKMEYQKCDNLQKSYDEIIEKFQNQTEKIKIFSKNEEEYNQLIGELTDVVKSQKNSIENLTLEKKQNFETIDKLIQNLELEQKNCYELRSQLKKEIEITSNLRTEKESLQSEISRLKLDIDTKNNLVTKSEADSEEKKIKFLAFNNEMESLKHALEVKNKMLEDQNETIRNLKKNLENKTNDQHSIASKLKNDIDELKEQLLAEQDLNDELQYQLEKKGNLIDNMKPLVDEYKLEKDKLKRDLIELQKKLKDRNEAILRIEEEVFKIKGTFKAKEEKLIENYKLKITEQEVVIKDMEFLLEDQRKKFGSWIHEKEALLKTIDHLKKNNELLVAIKQDHDKEMVLVLKELENQKNINYLKIQKMKEIFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Y3</accession>
    <name>A0AAD5U4Y3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008409</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000092">
        <property type="protein sequence ID" value="KAJ3224459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4Y3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119:SF0">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACB" evidence="5">
        <location>
            <begin position="63"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="251"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="291" mass="33607" checksum="A1591C3CB9714E6E" modified="2024-05-29" version="1" fragment="single">MIKGEKLRLSVSVLKVLLVVFAISVAAINEASIRRKKKKTITINKVKYENRNDTVEPEFVDDINENFNAAATFIRNNENLNLDDDTLLKLYALYKQATVGICNISKPSLLNFTESAKWEAWSALKNLKTLDAKLYYIELVENVTRWKQDLDVFEENSTEKNLKPKGMVYVSTMFKEKDLVNVESKTIFDFCKNNDLEKLENHIKQFPEEINILDEEGMSILHWASDRGNFRIVKFICENDNFKLLNAQDNLGQTALHLCVISEQNEVVEYLKRIGADQSIKDHDNNTIIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5B2</accession>
    <name>A0AAD5U5B2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000290">
        <property type="protein sequence ID" value="KAJ3220573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5B2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042135831" evidence="1">
        <location>
            <begin position="20"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="92" mass="10142" checksum="1144D7B3F638160A" modified="2024-05-29" version="1">MFSTKLVTICFTLLIAASANTSTSSVHFTKRTLKKLEWVTANEQVTSTAAQSDFPTTVSFSSTPAIQWVELQERDVQTVSYTQASQSSEPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5N3</accession>
    <name>A0AAD5U5N3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 18">Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</fullName>
            <ecNumber evidence="5 18">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">HK099_002397</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="18">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="18">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="18">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 18">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 18">Mitochondrion inner membrane</location>
            <topology evidence="1 18">Peripheral membrane protein</topology>
            <orientation evidence="1 18">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="5 18"/>
    <dbReference type="EMBL" id="JADGJW010000179">
        <property type="protein sequence ID" value="KAJ3222360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5N3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000007">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase iron-sulfur subunit SdhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050573">
        <property type="entry name" value="SDH/FRD_Iron-Sulfur"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004616">
        <property type="entry name" value="PRK05950.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921:SF29">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13534">
        <property type="entry name" value="Fer4_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="16 18" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8 18" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="14 18" id="KW-0408">Iron</keyword>
    <keyword evidence="15 18" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="19">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3222360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="226" mass="25903" checksum="78F772A83886A539" modified="2024-05-29" version="1" fragment="single">NPENPAEKPKIQTYDVDLSQCGPMVLDALIKIKNEVDPTLTFRRSCREGICGSCAMNINGTNTLACLCRIDVDLSKNTKIYPLPHLYVVKDLVPDLTHFYKQYTSIQPWLKRKDKPDEDKEHYQSIEDRKKLDGLYECILCACCSTSCPSYWWNSDKYLGPAVLMQAYRWMIDSRDQFSVERREAMQDPFSVYRCHTIMNCAKTCPKELNPGKAIAGIKKLMALDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5R1</accession>
    <name>A0AAD5U5R1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006925</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000063">
        <property type="protein sequence ID" value="KAJ3225384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034477">
        <property type="term" value="P:U6 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027521">
        <property type="entry name" value="Usb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012501">
        <property type="entry name" value="Vps54_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019515">
        <property type="entry name" value="VPS54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09749">
        <property type="entry name" value="HVSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07928">
        <property type="entry name" value="Vps54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10475">
        <property type="entry name" value="Vps54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 N-terminal" evidence="10">
        <location>
            <begin position="394"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="9">
        <location>
            <begin position="1104"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1389"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1389"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1408"/>
            <end position="1422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3225384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1454" mass="164436" checksum="646052919D683C9B" modified="2024-05-29" version="1">MNNLNYSSSEDDLENGVEFVQKTTITKKRIPRLPDFFEENVEVNKTTGQIRNYKHIKGNWSTLIFLKVPLEENVEKVISQINTNVRETNAVKRLKIPPFKATTKPSENFLHISISRNLILKKFKIEILVKKLEAKLKTLIDTFSYSQFNGFFIGFNELECFLNEEKNRIFVSLKVGAGHDYVKLLTDSVNEVLKELNFKEFYENVKKSKYDNFKENCNPKFEHMEMDNSESLYCGESEREVIISQETKGQIFAKESKNEHPFTFKDIGLNSISGILSDPHMQAKKGPQVLKGMDNLPQVPNTLIRKVKPAEFDPYLKSLAEVFDRFQYNQAMGVNVATEGTPLLGNDANNDAPLSALKTLIEKISGSPSLDSKRNRNKNKKAHNRMFSGNAPNIKSVPQIFFDTDFNLCNPHTFQTVCENFDITALDDENLLPDFVENNNVLQDKLGVYLDTVEIHLIREISRRSNSFFAALSNLQALHQETQNCVIQINELRRKLNTVSKSVVWNGLNIVQLKRRRGNLITLYGGVKLVSEITQTQPMIQGLLSQADFIGSLDLIGETTLLLRGADDKQLNQTVKTEMLTNNIKLIQYPTILPRSLDLRRVKSLLNLNEKMHEMMTLISDMMLKEFVNVIVPEIKSTPVLIPDFRHIPVQNRLNIELPLPTTPAASWTNNILSGKFSFSVLSQTQSNNINPLTALTNVDGVEFKAGDEKLKARLVPLVVGLLRMDKLTLAFNAYKEALLSLIKSFSKKYYPQMLKEDDELAQNSNSPAANSNLSKKREEKQSALAKHLRSLSFESFADLLVMIYITLLYTLQKISIVHSVIKEILDEAKERGIVVGAEDMKFFESNTTEEKTVPKPLSFLAQKLNEDDDDDFGSFDHLNMSMDARREDKLSTYERNTRGSSTFQEMIDDSADIVYSASDLAHMRCAKLIGVRSEQNAQLNPKEFYRLFGATWEFVNAGESLSGRMCFGLKSTILSQAKSFVNFFHEEKSKQLALLIENEQWSQAEVPVDFQMITEKILLSSTSNTALSPTSPNPEIINSITSLDSFHQSEENLDGSETDLTNLSSSFSSTKKNKLNKFNMSENYSEGGNSGSASLKYLLVDGQKFYAVGCLLMFLKMLTDYMQCIDNIPGLTNDVLNRILEVLKLFNSRICQVILGAGALRSAGLKNITARHIALATQSLGVIVYIIPHLKTALSLRLPPKQQVLLTDFDRLLRDYREHQNELYFKLVSIMQERLQVHSKNMLAINWDFPDSKDFEENCSVAMSNLVKETCTLHKVLAKYLNTETLKKIMSEVFKAYSIKLEEDLKRLDLFSSGGKNKLLIDVQYYIEKLSGLDLIDGPGNHMEVVVNNIKIKDKRMTQANVRSSGSMEFGGSSQSLNVPLANSNTVNMAKSNSQSSPSPERVNMPNFLNATSPANQNSFFETRKEEKGKRFSIAAFSKAFNSRTSTDNDGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5W2</accession>
    <name>A0AAD5U5W2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chitin synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006650</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000059">
        <property type="protein sequence ID" value="KAJ3225512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5W2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16457">
        <property type="entry name" value="RING-H2_BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011422">
        <property type="entry name" value="BRAP2/ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047243">
        <property type="entry name" value="RING-H2_BRAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07576">
        <property type="entry name" value="BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="295"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="8">
        <location>
            <begin position="325"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="618"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="487"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="630"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="647"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1126" mass="127856" checksum="D3C7CEA937A99C68" modified="2024-05-29" version="1">MFVLVFEIFNLNQGENLDLPTDIFSNLKSSYKQVTSSSSSKKKSSTGYNLLSKDFRFGPLTIESVEMSADADLSQISFPLIKTSKPHVQTTSGYFAAFKCGTTELNFGILHLYRDLNEVDDIMNNSNYNEPGPQYTSDEKKQLKGSGLILAVLAVPSYMTTQDFLNFIGAVTSMVSNFRIIRDSFPNRYIVLMKFRERADADLVYEQFNGLNFNSMQEEQCHIGISLEMLYIYLMIFVVYIKSVEFKSHAIPPYAFPPHQDVPSSLFFGSKFSNSEVESNQIPLAPHNLIELPTCPVCLASVTSLLTIICHHTFHSQCLKKWGDSSCPVCRYSTKSLQEEIQNECDTCRVQENLWICLLCGHVGCGRYVKGHAYAHFNETSHLYALELETQRVWDYAGDGYVHRLIQNLEGKIVELEAPANSRGPVPDLLEHGKGNSYVEDESGITQKKLDHISLEYTYLLTSQLESQRLYYESQLSKFQSVLTSQLDEVSEQVAQLALERDESKALYEKINESIPVLNKEKSSLERKLKVLTEKLVNLEKEYREEKALNLSLMENQLGLKDIIGSRDDLLKQKDKEIFELQEQIRDLMFFLEAGQKIKVLSPEEQQELKDGVVSVDTTVNNSTTSNSSNKKKKSRGKRSYPLAPYNQSVNQNTNLQQQQNQPPAQGSNQFSYFSSPANASSDNSSNVTSAVSKAFFNSNNAKSAPTDTFSKPFPNGYYQVDFPIKLPSAYPDLLAGQNNNLTYTAVNCGFTDFADRHPINRKPYSLKTPSAKLMIVVTMYNEDCDLFSLTMEAVYDNIKFLLDKSKQEMEDISLSGKDPSERLNPEAGHKPLNWQDIVVCIVCDGRGKCPYNVKVALEMMVQAHVFEYSSSVHVVAEVKKKSFHLSESKYPVQYVLCMKENNKKKIDSHGWAFNGFCPLLNPDVVVLLDMGTKPSVESFYHFWKHFDGDRSIGGVCGEIIVDIKGSWFLRRWINFWKQPMLAAQNFEYKMSNILDKSLQSVCGYITVLPGAFSAYRYDALKGQPLIEYFKAEGGKDKELPSKLSVATYLNISSANKYLAEDRILCFEIFCKKNERWYLRYIKEAKATTDAPETLGAFLNQRRRWLNGSMFAFFSGYFSMCKNEIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Z1</accession>
    <name>A0AAD5U5Z1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008656</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000098">
        <property type="protein sequence ID" value="KAJ3224265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Z1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="347" mass="39692" checksum="2FDDC8C96F42CF6B" modified="2024-05-29" version="1">MNVHADQIFEIEAIKRYSAKNQTDISFSKGQHFFVLSTNKTNQTYFVSTKYSTPFSRNAITGTVPINKFIVVHKPDPIPSRAKPDKYQNFTKKSAKIQYNFQLKSANCILASSFNSKAVSPVLSPTHRSAGTFHERRVSSKSFLAHFSNISLSHQKINYSRRTSLSKQHHKDSNDIPVFAAVEPLPPVPTSNDTRIARNSFLHPTNTPLIDKIFKVTIVGIIFEASIYKLLISLSSGKKYYVYKTFEDFEMMREKLLIEFSHFKEEIPTLPEKIDSGSIQETKSQAIELSVFIKKVIKLCDLLLGNRVLKELFPRQIFSQSDFITKNENTSNSNSERLFLDHRQVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U660</accession>
    <name>A0AAD5U660_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_001851</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000157">
        <property type="protein sequence ID" value="KAJ3222834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U660"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040050">
        <property type="entry name" value="ZNF830-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13278:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 830"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-type" evidence="9">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="51"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="149"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="277" mass="31982" checksum="CFB76CB43EF81C85" modified="2024-05-29" version="1">MNRLKLDKKSQKINSPLASYSTGKLQCIVCNTIIKSENLWLAHLHSSSHTKNLNKLKKRKVEASSSEGDNSTKKAKLNDVGAAVKNDKSSPVKKFNTENEKSSIEVSSDEDDEQDETSDLPPGFFDNSTKLQKDESNELENIPKKIENINEIDLKLDNFLSELKSEEKQSEVALNTDIELKELSKKEEEEELMLELEREFVNENLDQEFFEARIKNLKSTNEFFQKLEQDVSQSKKYELEKIKKIKKLKIKNKLRDLIEGLGEEALTEENEEDIWRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6R2</accession>
    <name>A0AAD5U6R2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000037">
        <property type="protein sequence ID" value="KAJ3226391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6R2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="89" mass="10087" checksum="F96B9AB248D512AF" modified="2024-05-29" version="1">MNTSKVCPGCHGETFETFKRRTNPKPWKIDEISVHGLLRCQSEVCQQSCGHPSRLWNRDGVATLNQKSIVESMTASDGRPNKFQRTLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U742</accession>
    <name>A0AAD5U742_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mannose-ethanolamine phosphotransferase gpi13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GPI13</name>
        <name evidence="12" type="ORF">HK099_001324</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000136">
        <property type="protein sequence ID" value="KAJ3223283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U742"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16023">
        <property type="entry name" value="GPI_EPT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037675">
        <property type="entry name" value="PIG-O_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039524">
        <property type="entry name" value="PIGO/GPI13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071:SF1">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="494"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="553"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="693"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="816"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="854"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="883"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="907"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3223283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1199" mass="137442" checksum="181933C6B081A8C7" modified="2024-05-29" version="1">MIKVLLYLIGIYIFSSGFLLSRLNLVQKSTRITGLNVKNQKAIIIILDALRFDFTHSSNNSNLYLNNLKILENLKENSASNALLLRSRSDPPTTTAQRLEAMLTGSLPTFIDLSSNFGDNKISEDNLIYQLVQQKKKIHFMGDDTWLNLFPSEDLHSVDNGITRILFDQIKKDDWDVIVAHFLGVDHVGHKFGPNHIAMKEKLLQVDKWLTKVFETIDNDTYVFVLGDHGMDEKGDHGGDGPLEVDTTTFVYSKKQIVNTDKDLNLFWDLVKKRADSNFNKNLGYFVSEGFRTISQIDIVPTISILMGTPIPFGNLGSVIPELFLFNNDSNSLPLSDLIRATRENSIQIYTYLKEYSSHSRELDFKKLNGLFEVTEDSFQKLLKFNKNLDAKSLQKSQLREYLEYCSKVYLDNIIFQRHSLLNARQVWAKFNMTSIWLGLTSIFFGFIYCHLRTPKKQQKAICWIFGLGMSLISFCFFEIHLEGKFVDANSLEISAFTFLITFVLCSWRFKKPSFCISTTPNLFKSLNLLSALLYILSILVPASDSFTYWEDWVVFYLLQTFGFVTMLYQLREKKNIDYTVFFLLLTRLSNYSTICRTEQGPSCVPTFNSSAMTSVASIKSLPILVGVQFVVFLSFYKFSKDLFRQKKNYQYDFVYLISGFFSLASICLLKILETLENNNIVGDAVGEIKLTLTRYFILPVIVLTLAFWFNSNFRHRNTHPGDNGSLPQPYLTSDESSNLMEEWEPKNKTVISSENNLPSKLKECEASFLYLNFFTLFVYVPLLLTQKPMGGIILGMGYLRILCVVKMNFGRDIPVLMGIVFHLIGLHTFFTTGHQTTFSSIQMEVGFIGLRKVNWYITPLLIFLNTFSGLKSNTVLNLKSFVFFEGYIFLSTFFSSFMVQNFRRHLMVWSVFAPKFMYTSIAGLIKEKILIVITGASQGFGSSVATQCNLEFTKMVLISRSEELLQQTKNKIKLTDNTEILKLDLSIEQDFKKIFSKYKDLSFTKVYLINNVGTLGNLDFINTAENVSGELSKLNFNSLQHEFNLNLNNCFLITTEFLNLFKNGFKKNAAAIPHLKIHIINISSLAAIKAFECWSIYCAQKAARDMFFKTLALEESSEVKKKDGVTVRILNYAPGPLDTEMQKKIRDQMPPIPLRETFIKMKLENSLINCDDSAKVLWNVLKKDDYNNGDHIDYFDCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U778</accession>
    <name>A0AAD5U778_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U778"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10519" checksum="27B903A99F2E4DEE" modified="2024-05-29" version="1" fragment="single">MFCLETLFHSRVVECKGSDEIPVELNMKLDTNLKLKSVYSSRKKVSGSRKAYKCNHCDYEFYFRNNSASKHLPTVKKLNGKKKRSSKFHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7K4</accession>
    <name>A0AAD5U7K4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005961</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7K4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131">
        <property type="entry name" value="TNF RECEPTOR ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10131:SF94">
        <property type="entry name" value="TNF RECEPTOR-ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="558"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="603"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="714"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="22"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3225905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="765" mass="88273" checksum="DCFFC673FDF41FBD" modified="2024-05-29" version="1">MDALQQNDDYNYVFEFNPNLICPMCCFPFVSPTTTDCNHTFCEYCLTKSLSISQKCPSCRSEISKVTPANLIIANLVNELMVYCNEKVNGCQWKGERSQLHNHLESECMFVLKKCQNEGCLKMIKKVEYKNHLEIHNPASKLYCIQCKYCQEFIPFLDIESHGRDCGETDSKCPSALFGCTWSGKLKNYLRHINTCTFAQLLPYFNIQESKYRSVVEENMNLHKKMESLTLEVEQLRQELDQEREVEFRKEIIFEEFNQRFCNLELKQDMALLSETSRLRDELSNLRILCQSIQMQLIHAGNKNFNKSSNDHSKSRILEENLRNAGLKHGGYALPNCPFETSTFPPNAKSGFLIYSPAISELENAENNNLSKDEGTVEPEVIDSWLLLASCCLRSFSILFLTIALDRKRTYCSSATTYLLFGQSPNNPSPVLYPSDAASSSSSTYNTHSRLPSSYLPLPSRADANSPIFVSKLVPAESESGDLVENDDDFDEEEESILKKLKTSLMKFPSWNFIFCFLFVLRLTGLLLVIDPPHLRKDFWRFPPALVYPQEEEFYSPIFFYLSLILGLIQCVPVFMIAYHIVIDQPKFAQVVNSSGVSQRKKFGPTIKSKIFLVLGVLFSMIWFVEPSITSRGITNLVLSTGNSSLSFSHRSCPIPPFWWHNESDTIAATYASEFFQIDYYEKNERIYFNEILVQEEMEIPKEKKEKEVALHGWASWVDFTSWCGLVGLWLLFWNLRIEYKRIKDAWVKFIVLQVQETFAFRRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7P7</accession>
    <name>A0AAD5U7P7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CORO2B_1</name>
        <name evidence="11" type="ORF">HK099_005732</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Binds to F-actin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7P7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000197">
        <property type="entry name" value="Coronin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 9" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="10">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="78"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="128"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="171"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3226026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="460" mass="51046" checksum="1E1B109709D36313" modified="2024-05-29" version="1">MSRFVRASKYRHVYGTGTANKRDQCFDNLKVSKNAWDTNLVKANPLFISVNLEASGGGAFAILKHDQTGKLPESNPVVNGHTGAVLDTDFHPFNDHIIASASEDCTVKIWSIPQDGLTENLITPVVSLNSHGRKVGHVLFHPTAENLLTSASADFTVKLWDISTGQEKQTLTGHTEIIQSLSYSYNGSLLVTTCKDKKLRIFDVRTDKVVQETNGHAGIKGSRVNWMGPLDKLVTSGFSRSSDRQLFVWDTNNLSEPLKQENVDTASGMLMPYYDESTSMLFVAGKGDGNIRYYEWVDDEKGLYFLSEYKSADPQRGIGFLPKRAVNVNDVEVTRAYKVHVGMVEPISFKVPRKSDAFQADLFPDCIGAEPSVTLEEFFNGVDRPPKLISLENGFSAQTDVKEFVSTAPPPVTEDITGPKTEKEYQDAYHTLRKENDDLKNAIASRDIRITQLEAQLAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7S6</accession>
    <name>A0AAD5U7S6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000053</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7S6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22696:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="300"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="228"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="355" mass="40738" checksum="5EDE1687757B342B" modified="2024-05-29" version="1">MHLSRLPVIVTTLHSLTYLITKGKIKTASHVLWRPKIKLNEDFTGVLFKLGSSCLIASHSLGMMNEMDPINVAAVDKFINGFAKKDFVDGEEVTVEKTDISSLLFSSHSVSVIRYWRALVKIVIGFCKSFFYYSKKKEDMSIFFNLETRENHYSDAMDDECDEDYQSDSNDGISTSSGSEDGDFDVLDQELFFLAKDLNSEAKQITANPNSKFSIFNTLNYLNFMESLQKENTVLTRSQRKLKKLEINNYFINSNFSDMHTAAGERKELLKLTLNRRKRVTDEIRNAINENYSKESSFSCRVCVVCHCEKRTIVLRPCGCLCLCDDCREALAIRRFNDCPCCRRKVRGFSKIYEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U837</accession>
    <name>A0AAD5U837_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008321</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U837"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF62">
        <property type="entry name" value="LIPASE ROG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="3">
        <location>
            <begin position="17"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="409" mass="46797" checksum="B07F52490437FAE2" modified="2024-05-29" version="1">MAEVANNPNTAVEKTFKHLILLIHGLNGTPEGDMKGLKFLLKRKLQIKFSDAVEQNFEIHAISSNRGKTNDGIIKGSERIFEEVLDLLKNNKNNSINLSIIGHSLGGIYGRYLIFLLEKHKLFEVKLNPFNFFTLATPHLGSLHHIKQFGFNSVPSWLSNFLLTQTIRDLMLLDEKLLMFKMCTEDEFLIPLKRFCRRVIYSNLRYDLSVSYETSAIKIKNNYFDGLFLKKKFGGLTTSCILNDDHDENKLETFIDNNEGLEESNDEDVQIIDANNMKKGSHHGKNGEVPFSDENHNNIEESGDLENYPALNTNDNFCKEVDHKKLTESVESSLDAETNSTDPVSPKDKQREKLMFDGLNKLKFERYACIFNKPLTAHIDIIGKLDNEKSLESNLVLNHIVENFCKNVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U967</accession>
    <name>A0AAD5U967_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U967"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="181" mass="20817" checksum="62F726751D01F4E2" modified="2024-05-29" version="1">MIEVLKLDGSKEFNVARDNLFCWTNGVVINRSLKGQGIQNNGLLTYQLSGSGNVALDGFGDFITYEVFPGEKAEVNPKCLIAWESTITPKQKNVIKKVIYHKYSKFQFKFIDEFKKDRLKAAKMVLKNFGVNFFTLNKNLLIFVWEELTINSFFRLKNWSFGQTEMYQVEGPGIIYLSSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9E6</accession>
    <name>A0AAD5U9E6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRKR-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PRKRIP1</name>
        <name evidence="2" type="ORF">HK099_005402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9E6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009548">
        <property type="entry name" value="Prkrip1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507:SF0">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06658">
        <property type="entry name" value="DUF1168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="215" mass="25014" checksum="CAE6B5B931424A7C" modified="2024-05-29" version="1">MGSPTKGHKKRKELSDELDVSDDEETVRVKRIQNDKLNEVNRAKLERMFSKIDKPVYIPDKPKPRKLHEPPEFVIGSGSSAGAGSGEFHQYSKIRRREFARTKFHEANDKKIKEDLAYQQKLEEMKKKDEEKTSKNREKRKKKKEKKKEFKLESSKNSVDNKVEDIKNEENSTNNKNINSLQKTSGNGVMVENGIEHSVNNKEKKQVKFDVKLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAD4</accession>
    <name>A0AAD5UAD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L16B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL16B_1</name>
        <name evidence="5" type="ORF">HK099_005333</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAD4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3250:FF:000001">
        <property type="entry name" value="60S ribosomal protein L13a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="202" mass="23141" checksum="1AD9C2FFA5B489B5" modified="2024-05-29" version="1">MAFEKEVVIDGKGHLLGRLASIVAKQLLNGQAITVVRCEEINMTGPFFRNKLKYLTYLRKRCVVNPNRGAFHFRAPSRMLYRVVRGMIPHKTPRGAAALERLKVFEGVPPPFDKQKRMVVPQALRVIRLAPNRKYTVLKRLASEMGWKYEQVVDRLEAKRKVKSAVYYEKKKSLSKLKAKAEKNSAKELKPIKDKLAAFGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAY9</accession>
    <name>A0AAD5UAY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">RUVBL1</name>
        <name evidence="22" type="ORF">HK099_000437</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAY9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013899">
        <property type="entry name" value="DUF1771"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08590">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01162">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0804">Transcription</keyword>
    <keyword evidence="13" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="10 19" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="20">
        <location>
            <begin position="584"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="20">
        <location>
            <begin position="613"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Smr" evidence="21">
        <location>
            <begin position="834"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="19">
        <location>
            <begin position="584"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="19">
        <location>
            <begin position="613"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3227764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="917" mass="103633" checksum="0C09BD0E7CEBBF57" modified="2024-05-29" version="1">MRIEEVQSTVQEQRIASHTHIDGLGLNEQGFAEPIASGFVGQENAREAAGIVVDLIKSKKMAGRAILLAGAPGTGKTALAVALSKELGPKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKEIKEVYEGEVTEMTPEETEDPLGGYGKTISHVIIGLKTVKGVKQLKLDPMIYESLQKEKVLIGDIIYIESNTGSVKRVGRSDAYATEFDLECEEYVALPKGEVHKKKEIIQDVTLHDLDAANARPQGGQDIMSMMGQLMKPKKTEITDKLRKEINKVVNRYIEQGVAELVPGVLFIDEVHMLDIECFTYLNRALESSLSPIVIFATNRGVCTIRGTDDISSAHGIPVDLLDRLLIIRTVPYTQEEIGVILSIRAKTEGIKIEKESCDFLAELGVKTSLRYAIQLLTPSMVLAKISGREEINMDDVDEVDKLFFDAKASGKLLQDFAENYFCVFLLHHERMDENHNDNFYTSNEIYSCEENLLANTYSQQLPYYSYEKEEEEILLSILETFDDERDDISPMQILLLLFPYFREEELYQIFEDHNFDISKTLDVIHNLANNLNYSTSNDNQKVDTNNEATEKKKTVCRHFLNGHCARSDCWFSHDTGNFLCKYWVRGNCLKGHECEFIHQQFGNSLALELGAECSAPTQVHEAPVNFFPNDQVFPSLSSANKSVGVAVNVGRVKDKNITVVEDIIVKKVGKKKNKQKIILNWDSVPYQPKVDSYKIPEACAIEKYSKPEKRKERVYIDWVSTGKEASQLYEKYRKDAAVLAVRRNELFNRAEAAFKNHQHILAKKLSQEAQMLNQQMHSLHRDAAEKTFELRNKGLKKSLIDLHALHPDEALELCLKKLDYLKSKKKTSTKEKIFIITGTGHHSTRKNKLKPVVTNGLIENGFEVKEGTMKNDTNGGVLVVYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB76</accession>
    <name>A0AAD5UB76_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">TIM50</name>
        <name evidence="17" type="ORF">HK099_007306</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the TIM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB76"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000019">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10 13" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="FCP1 homology" evidence="16">
        <location>
            <begin position="173"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="415"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3228025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="474" mass="54358" checksum="AC74CFCDF1D259D2" modified="2024-05-29" version="1">MRNFSSTGLKNKKSERIFQQVNKVNQPPKSKQVNTGSSEKSNSDAVRPNTRKSAENFASLNSMRVETAEEDVKSEEELQKEEARRERLENTVNEAEKVRHRKILKNVFLWSGIVTILGGFLMGRPRENEVPIEGESFLKGYIRRIGESLTTSYDSAAAPAFGEKLLPDPLPEPFHRAHTLVIELNDSLVHLVWDKEIGWRIATRPGVKKFLAYLSKYYEIVIFADTPANIAQPVVEALDPYQMALYKLFRESTRLVKNKMVKDLSALNRDLSKVICVDVNPDAYSLQPENGIPLKKWVGEKSDRELLRLMTMLEELAIFMTYLKLEDVRPILNKLRSINAEDLPLAWETHKAQSKAAFQAQYGKAGATPKLGLFAQKQSGMKDVFTLIEGTNMNNKIFITLFVAYAKEERAYFEKEQVENLIAMKKARDEQIEEQKKMIEDMKAKKVKMFDLMFAYRLNFFQDNPTAVKSRESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBM1</accession>
    <name>A0AAD5UBM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBM1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="267" mass="30395" checksum="41F1A93F0183D6A6" modified="2024-05-29" version="1">MVFLSPRSASLYQLPDLVRNKDLFAYTNKEATEIVLCPVCNNRSSSKKSETLVPRRAKSAHVRNVQFRRIGSNDTLKVQRDEKICHMVNPRSTSILYSHAVSKKLSFYKNTNNRLLRLKNLSPRSTSLTLAIPKSPILISDKSNCSQNSRNLSNRNVSLNCHLRQRPSILRTSTRNNYFRSFSPIRTTSLGCNFKQEKSFYNFTSEARSYPNSNPICQILPERTTSLQCIYDNLCDEFVNAKGSVKNKDDDILSIERVRGSSSNSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBW5</accession>
    <name>A0AAD5UBW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="815"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="917" mass="104662" checksum="4DFC234C378A262D" modified="2024-05-29" version="1">MLTTPTNSRSCNTKINSNSNNTTSSSKIPVPKKGTKPLKSLVSTSFSETDIASLSIDSPTTSLKKVVQNEIYNSKNRTDDIIHEFKNFSKIFEKKNLQKETKSTTISQTPQTILKKLSRIEGTKTNESSQTVDHGKNSELLLPNESSKNTPNRILALEAKRVTKFLNKDSVVFDEVNCFFNKENDNILEDLIDLNDVNEKFGNNLTSSIQEPNISEFSKISTANSFDLTPALKSALEAKIVSNYGNGVQNRNKTTFKDQSTIDENEIIFDFEENIYLDEHLNFNVKSLIKKELTADVEENIDVEGTTDEGKISEKIDSVTASSNDKMVDVNFKNEFLYKTPEELKSEEIEISETSMEAVSFKCGIDAITPELSESLLNEEQLAKFFEEEPKDSTTSKTDDVLTLEDLSQSHSKFSENDQCRNSFSDQENVLEGSFKTQNFITEDAINSDYNLENYNAKNRNPDEDGEIELSFFKNELNNNVPFSAVSERTEENSILKSEDEKKESSDDSDDQSDYNSPSEQRRLRMSNSLPHKEKNLTEEKIDLTQIKKSIYSLPNKHIVAGETMNFVPKECNLEIKKVLKCDKLDDNFNKITSSICENEQKLNSDQPKTEIVHIKSEETVFFNKSDDQILRQGPGMLDSNTFMVNSKMEIEISNELHKLSKKSLVDSVTKTGGLTGDLMEKKISGNYYGFSKDEKPGLSEVTSTENNSEYDILLEKIEAEKLYQRSRSEAEQNSTLEKNVKFITPINGNVTKKNKSSVLGNYAFLDADDLEKSRSIIFKRNPKLDVLNETKFNRKLETDVDTGLTKTKKKKKTILFTSLIMFLLLMLLFLYRNVEFKDKIDFYFNSSLIIQYFKRNVLETFNYFFYEKPKFQKFSLEALLLRAEKTYHYLYSLVSSMVSNFLESFLGTNDLDYIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC72</accession>
    <name>A0AAD5UC72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lysophospholipase NTE1</fullName>
            <ecNumber evidence="3">3.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Intracellular phospholipase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Lysophospholipase nte1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Neuropathy target esterase homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PNPLA6</name>
        <name evidence="18" type="ORF">HK099_000013</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NTE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046470">
        <property type="term" value="P:phosphatidylcholine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001423">
        <property type="entry name" value="LysoPLipase_patatin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056556">
        <property type="entry name" value="NTE1_P-loop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF29">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE SWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24179">
        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01237">
        <property type="entry name" value="UPF0028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 14" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="10 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="43"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="16">
        <location>
            <begin position="599"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="16">
        <location>
            <begin position="742"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="17">
        <location>
            <begin position="1174"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="14">
        <location>
            <begin position="1178"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="14">
        <location>
            <begin position="1205"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="14">
        <location>
            <begin position="1314"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="14">
        <location>
            <position position="1207"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="1314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3228458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1471" mass="164072" checksum="A48EC30D649E0E26" modified="2024-05-29" version="1">MDNILETVTTTVLKKINPTNFISQVEDSHIHNIKRNDNSLFSYLLSLLFSTITFTFSSWTIFTLVLLLFALAYIVFRYRILTRYSRLPVNDTKGNSIGYDDLRPDIENVNNENSQSYQDFFVVAEGEIQVFVKSKNQDDEDEVEFDVEYDNKQWSGHILLNEVQSGGTVSSLFNILSVFTDGLNAETDPFEASSGATPDEQNDLFPGLRRNESNAVPSNSVQVPPLLNNNSVNLKISETNVESEVKVIYESINDFSDGDNNKTVLSEKESELKTISEKNIKCEVKEKNKSNFGYKNLHPDIVARASKDATMVVIPAEAFKKLAEKYPSAAAGIVQVILVRFQRVTFNTLYRYLGLSKELLKIEKNVNKFSNEGLPVNFMDGDWEEYLERLRERFGLHGSPSILQNHSLCSSPSNISKPLKKNFPLFSDTESTFQRPGNPIKNLHIQISQSKSTANSNSKHSVQMKENYNSDADYDDSEFEVVPNSGKQFPVKSKHFFFDDMDEDELRLKQCCFDLISKLIGFCPNITTPVNNSKSHSMRDLQRDFELNNYLINDLLNGYSPKKSQAKRRLSIDSNTEDDMSTTSSIGAGSNVSLLIEPANDLQILHYKPGDILCKEGDRVEGVYLVIDGYLEASMKSSINEMANATSFTSSKDLDNEYDSKKVRTLKKSLFIIGEGGLAGYLSALTGHPSFITLLAKTDVLVAFLPKLVLDKYVEKSPKILLTLAERLINQLSPVVLHIDIALEWGHVPSGHILCRQNEKAEDIYVVLSGRLRTILEGKNNDKLDIIPPESPKLKKKGNSKKGFFDGFDVNDGIGTSFFPVKGPSIATSYFEILQEHGQGESVGELEALTGSRRLSLLLRTTLNFIFRPGTLHAIRDSEVAVIPKNLFVALSVQHPAITVQISRIIAKKSQADNLFKNPDFLPGGLGSSSSPYSSSSTSATLASNNCNLKTVAILPVHANVPIAEFADRLQESLVLLGASVAVLNTSSVMARMGKHAFSKLGRLKLTSWLNEMEDRHRLVLYVADGGVGSPWTQRCIRQADCLMLIGLGDEDPSIGEYERLLIGMKTTARKELVLLHSERHCLPGSTSLWLKNRGWIHAHHHVQMRLKTGNSYSKVSQRNVPTLTLLRSQIFAKYYTADSQHIKKAGHSTDVHSGLRSDFARLGRRLLSKSIGLVLGGGGARGIAHVGIIQAFEEAGIPVDMVGGTSIGSFVGGLYARENDAVSIYGRAKSFSNRMSSLWRKILDITYPFTALFTGHEFNRGIWKVFLDTRIEDCWLPYFAITTNITWSRMEAHRFGYMWRYIRASMSLSGLLDGGYLNNLPADVMKVLGADTVIAVDVGSADDNSDVNYGDSLSGWWVMWCRMNPLAGIIGPDVSKIPAMAEIQSRLAYVSCVKQLETAKSIDGVLYLRPPVNHYGTLEFGKYDKIFQCGYEYGKEIVANWERDSVLEELFGIKTEADDKKGRQNRRASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRE7</accession>
    <name>A0AAD5XRE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002034">
        <property type="protein sequence ID" value="KAJ3199800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRE7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="366"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="418" mass="48121" checksum="E41D50A308D461B7" modified="2024-05-29" version="1" fragment="single">MYMQYTNIEENFDEFSGSISTQENFRNLVLDEVKYQHQPVNAGKIQMLTNSKKNDVATKIIGSDVSNFSSSSNLLSMSHCSNTDLTLTSSQHNLEQNDFFNQEYNPTEKVGFNNKSELDKALPQLWHHDYNTSNFNDALSYNTHHEHEIASNLHILELEMLANTTRGAPEVSCLGESQMSLFESDSCAFKGQSEPFMETNNYYQDPTELGNPSKFLTETPTGWGNSYEPQNQVYNTFRQDIQLNYNTDFFTNEQQPLYPNCAPQLENQAISSTLLNLYQDIKSSKNNIKEASANYNSVNLQHNNNPLYSNIQEYQSRYPLSNSLKNPGQTIIPKKKKNISKGINSIQQQFLSKNVHHPYYQPIYFKEKTVVALKDLIRENDALKREVAEARKQREVEEMESAQWLIDLRTFTNLKSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSC9</accession>
    <name>A0AAD5XSC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001256">
        <property type="protein sequence ID" value="KAJ3204878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSC9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="145" mass="16302" checksum="46FA5CA2F26B0FAD" modified="2024-05-29" version="1">MKKTKLKPIPKQHHQQLTPSQVEKIKNSPENNNNNHNNNSSSNNQIKNDDLPNKSELIPPCSKLYSIKETSSNSGFSNGTSSVDTVSLLLYTDDMLSFKSASGSTKNEKLLDLVKLGNKLVNFRLKTLVEEDKLSKKKKIKNIIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSD3</accession>
    <name>A0AAD5XSD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000967</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001249">
        <property type="protein sequence ID" value="KAJ3204953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSD3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="55" mass="6227" checksum="F06AEF2DC25C6EF8" modified="2024-05-29" version="1" fragment="single">WDSKGLKSENLEVPPTESVTLLNPETPEPVPLTWMLLFSEEKFLSSISDFSLVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSD6</accession>
    <name>A0AAD5XSD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_001404</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001393">
        <property type="protein sequence ID" value="KAJ3203690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSD6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF32">
        <property type="entry name" value="CHOLESTEROL 7-DESATURASE NVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="11">
        <location>
            <begin position="197"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3203690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="265" mass="29966" checksum="59B9711276D7F971" modified="2024-05-29" version="1">MPEGKTLPEEAKEFLDVAFSLGIFSIKDYVYKLEANTENEEEVEVVFPNQYSPDSRIMLKYTITSFFAVILRVIFKMICEILNFQLPNEIQTVALVSLTTLTTLLFFRGFLTYFYAPLITNMLLIAVIVWDYYEFNINSVSSINSGLTLILGIILGYLYNKRGFAAEQNLKKFRSKETISRKIRAKSFPKAFPSGWYRLFSSNEILPGEVKHIQALGREFAVFRGKQNGEVSITDANCPHLGANLGLGGKVIGNNLVCPFHGKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSS0</accession>
    <name>A0AAD5XSS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001080">
        <property type="protein sequence ID" value="KAJ3207095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSS0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010770">
        <property type="entry name" value="Ecd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060:SF0">
        <property type="entry name" value="PROTEIN ECDYSONELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060">
        <property type="entry name" value="SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07093">
        <property type="entry name" value="SGT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="321" mass="36479" checksum="5F6671A6BF031F3D" modified="2024-05-29" version="1">MQTCGFEMLMGGNLSNGTYDFSNCRDWAAFINTLKKKGFFKNELEGSKEYKRLMTIAKTEFLKEKEPYLQLKDIITEYLSSFPLEEGYTPNDEPEDTEEWIYINEQELDAELSDLEKDFDFDMDLDDENNSDDDNSIDETREKLKQKKKLKGMMDLNNAVKGVKNFLNSNSGVEGVNYNSANENILSHFDDSNTLASESDSDDEDSDFNEDFDGTQFNADMFISTLKSLVGDQLGTDELGTEENLEDDEKTTEMDEYMNSMRRELSETKIRETFKSGEIEGELDLNINLAGNLLNSLEASGGEFGPVDTLLDTVGVNLKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUH9</accession>
    <name>A0AAD5XUH9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cation efflux protein transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_006099</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000504">
        <property type="protein sequence ID" value="KAJ3216020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040177">
        <property type="entry name" value="SLC30A9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13414">
        <property type="entry name" value="HUEL-CATION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13414:SF9">
        <property type="entry name" value="PROTON-COUPLED ZINC ANTIPORTER SLC30A9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="7">
        <location>
            <begin position="27"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3216020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="338" mass="37382" checksum="060CD8963D78A0CB" modified="2024-05-29" version="1">MRRDVTMVEGNLQRKETLEGSQKVVAFAITSNFLMFSGKLYAAIVSGSSSMFSEALHSLADILNECLLMWGILRSLRQPDPDHPYGFTMERYAWALVSGVGIFFLGGGVSIYHGVSSIIYPHALGDPTMAWYVLGASLLFEGATMTYAFRTIRKAAIQNDVSTKEYVLRGADPTTVQVLLEDVAAVTGILIAGISISLSSYLAMPILDSIGSISIGLLLGSVAGFLVKRNISSLVERRMDLRKEREIVRVLSEDPVVKTEILFQGDHITERYLHSLSTEELEKELLILKNSKTDEEIKEWVVKHGSGVIGMLGSEVDRLEWEIKKAVPQVKHCDLEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUP8</accession>
    <name>A0AAD5XUP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000465">
        <property type="protein sequence ID" value="KAJ3216674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUP8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="137" mass="16011" checksum="9B46DA7DE1060BCA" modified="2024-05-29" version="1">MDFNSTEFNSTDFNSTFDNGDFNNTVWYTPTSFPDTRAAAGIVSSFFVLIMFLSCAKCCFWGLVIYYCCIKPSRDNEKLQQQLILQNNLMLAQQQQPMKYHQPTDNYQHNFNHNYSQQPYPPPHSQNVPQPETYLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUQ0</accession>
    <name>A0AAD5XUQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Centrosomal protein of 70 kDa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005818</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000470">
        <property type="protein sequence ID" value="KAJ3216598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUQ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070507">
        <property type="term" value="P:regulation of microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037692">
        <property type="entry name" value="CEP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14594">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14594:SF1">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="668"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="205"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="286"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="425"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3216598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="728" mass="84670" checksum="E58A64B72FDA9C52" modified="2024-05-29" version="1">MDTHSNLSTPRSNTSSTNRSEKDVTAFVKYLLDGSGAEENVDFIALRKELDINQLGSSTNILDGLSYASSTSPKRLSEEEVNIFLEQFSEVRNNGNLSKDIVESTDNKIKENQLFQNRSNSKSSPQNVNLKETVADSQILDKGQREYSKTAENEAKAIEEYLENDNRTSFTKQREEEAEEILHNLSESLKWNGFDPLPSKVFSKASLTQVQIENLNQNLTKILNELEKKSALIHLISEKNNDLELELRKEKLLVKELNLKNTDSLNLDTKINLDLKKELESNFFALNELKLENVNLKNVIKTEKIKFVEKNRELEEKCETIKKLESDLSDILDKKEKERLRIERTFHDVTQKYHRNPSKSGLDRLTLEVISYYEEKLKNLELQLQQDDDHISYKSREYTDNSNINTSNFHKRESLQDDEIKDFIQHQLEKDLLETKKLLKKTENELELIKLENLNKLNNASDALDREFMSTRDLIQNDKRAYKLSTYSLESYSKHELQDMISNVCVKLGIENIKQLSSDLNDLERVIKLISQMQTFIDIVDDLVWQEQRSSKVPPHKLNDTLKLLKNLLPNREKFMELQDFLLSLMEIVGQKDKENINQLFNTIDKYAKAYTEQEKSIHEQLSNLEFILKKAEPEALKLDTEMNAEKLIFYTIQYIENKIMEEKQLRKSLRSSSKSEEKNLTVEGEEKDLKALGKVKNMMSDGEDEKKVAGHMEGKEEFNLFDSFTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUR3</accession>
    <name>A0AAD5XUR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001681">
        <property type="protein sequence ID" value="KAJ3201730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="457" mass="55165" checksum="04599EBFC2728B64" modified="2024-05-29" version="1" fragment="single">MNELRYSINRHFESIINITEISELSNIKNTLPELEVRFNDNYIKRDVFRKTFDHLKKVNGIQKTDVQDISIGNLLNKQIRIIREKNKDDIYMKKEKISSIVLSHTYSIRLIYSIETIMEHDPSRFDINKKEGKRTRRRVTKKVSFGKNNEYTFEIFFTIINKTKYEIEVELPTEKINNNNHIEVSNYLYEIVNSIKNKYYYFSKHSLTVNNQIKNLYPPIILSKPEILKYSKLFNDVHKNRCSNSKYVTYKLDGSRKLLVLYKDEVYTYDEINSIVYIRALNSNADYKLTILDTEYYNNIYYVFDILFIDEVDIRNETFNDRLKEINKINMQFIEKYVSIKEYKIFNDYKSLYNSVTYLYKNYKDKYNTDGLIFSHLNKNYIYKQYKWKWNMTIDMKVINKKLYSTSSDKGMQIHDKFLIQNYSKSLEGKICEFEVLKDLRTLKYIKIRDDKKNPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVU0</accession>
    <name>A0AAD5XVU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000281">
        <property type="protein sequence ID" value="KAJ3220682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVU0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="237" mass="27761" checksum="C8C9E2F3B82EDA46" modified="2024-05-29" version="1">MKNIVYYSNFGYYLLSILSTLIFSFSNVQFIVITWFCEDVDDRSQINIDAYVFQIIYCGLVDTILGMLLISKLSQRFLNSHQINSSPKVKKLRKEILVNLMFWIFCIWGSALLMYFAYFPLPSFKIYRNLLEILENLSLTLQTIEFCLSIPYFNHLTRLAKIVAGVDLNYDEPDRNQSKRIADFKHSKQSLKKLNISSDFTTILDTSKPESTSRYRLDCLSLNYDVDIENHEEITSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW97</accession>
    <name>A0AAD5XW97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Echinoderm microtubule-associated protein-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EML1</name>
        <name evidence="5" type="ORF">HK099_003392</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002222">
        <property type="protein sequence ID" value="KAJ3198954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW97"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF50">
        <property type="entry name" value="ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50960">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EML-like second beta-propeller" evidence="4">
        <location>
            <begin position="2"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3198954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="113" mass="12506" checksum="34A41FBFC6EB993E" modified="2024-05-29" version="1" fragment="single">SNDGKRITSASSLRDVKWHTQSCILGWPVQGIWEKGMDGTDVNWCDRNPKQTCLATGDDFLNVRLHVYPSTKEGLPCKKFSGHGSHVTKVMFSTKGDKLLSLGGMDGCCFQWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWD3</accession>
    <name>A0AAD5XWD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002066">
        <property type="protein sequence ID" value="KAJ3199654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWD3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="53" mass="5911" checksum="EADD5244C6A7AF01" modified="2024-05-29" version="1">MTVIDFIITKNPIGWNSIVGCLFILFGFILLNLSDTPKHPVEAVIGEDEPLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWH1</accession>
    <name>A0AAD5XWH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000203">
        <property type="protein sequence ID" value="KAJ3221891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWH1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042074537" evidence="1">
        <location>
            <begin position="18"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="250" mass="27082" checksum="A7E2F02220860CDD" modified="2024-05-29" version="1">MKFSVLATVFLSTFAAASYITPLSKRDPLPYEDIQLIVDGANEMIQKYDQDMVKIITDAKLDPKETLAQGSTSGQVNIGICKARGEVGYYLTNLVGLKKLNIKNVEYVSNDFNADAGLLTLVIKAGINPIDLSVDVLGHAIGHCGFLHPHVDISGNVDVNGMKIDILTSIVLDINNGVTVTAAEIAAVAVDFTRIDIDLDGFGIIFNPLLDIVTDSIRGRIKAKLISLVDDEIKPVLQKVVNSKLPFKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX32</accession>
    <name>A0AAD5XX32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">LCB2</name>
        <name evidence="20" type="ORF">HK099_006251</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:14761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="EC" id="2.3.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000528">
        <property type="protein sequence ID" value="KAJ3215663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX32"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000004">
        <property type="entry name" value="2-amino-3-ketobutyrate coenzyme A ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000047">
        <property type="entry name" value="serine palmitoyltransferase 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 17" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="19">
        <location>
            <begin position="156"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3215663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="536" mass="59667" checksum="A108DA4979621927" modified="2024-05-29" version="1">MGRGQGKGKKAFLQQVPPISTLDTITKPPTIISPQQMHRTNSNSTLHTEKTEIEEAPIFTLVTTYISYFILILFGHIRDVFGQIFKKEHYEHLHTKNGMAPINHGFDTFYHRRLYVRIRDVFNRPITNVPGRTVTLLDRTSSDFNKTFEFTGKTREVLNLSSYNYLGFAQAQGPCADAVEAAVKEYGIASASPRMDVGTHALHVEAEKLIANFLGKEDCLLVSMGFATNSTTLPALVSKGCLIISDELNHSSLVYGARLSGANIRIFKHNDMEDLEAVVRESISQGQPRTHRPWKKILLVVEGLYSMEGTICNLPKIVEIKKKYKLFVYLDEAHSIGALGPNGRGVCDYFGIDPKEIDIMMGTFTKSFGAAGGYLGATREVIEHLRFNCQANIYAEAMAIPVLQQVITSLNIISGKIEGGEGRRRIQQLATNASYFAKELRKMGFIVYGKDSPVVPLLLFHPAKIPAFSREMLKRGIAVVVVGYPATPIITSRVRFCLSAAHTMEDMNFALEMCSEVGDLLQLKVTSEGKKHLKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX41</accession>
    <name>A0AAD5XX41_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Micrococcal nuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001202</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001317">
        <property type="protein sequence ID" value="KAJ3204283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX41"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031332">
        <property type="term" value="C:RNAi effector complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00175">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000018">
        <property type="entry name" value="Serine/threonine-protein kinase 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000001">
        <property type="entry name" value="Staphylococcal nuclease domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000002">
        <property type="entry name" value="Staphylococcal nuclease domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016685">
        <property type="entry name" value="Silence_cplx_Nase-comp_TudorSN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF2">
        <property type="entry name" value="STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017179">
        <property type="entry name" value="RISC-Tudor-SN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="181"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="339"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="506"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="5">
        <location>
            <begin position="714"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR017179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3204283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="930" mass="104000" checksum="611E56AF67422412" modified="2024-05-29" version="1">MNGYAHVKQILSADTLVLRGKQIQSDTPLKSKPGPPPEKLLSFAHITSPRMGTVKEPEKEEPFAFQSREFLRKLLIGKEVHFKVEYKTIANRDFGVLFLPSSQAVNGETNVTKILVKEGWVKVKQPEGKRELNEEQTALIELEQEAKTLGKGIWSGNNLTRTLKHTLDGDIREFLNLHKGTPINGVIEQVRDGSTYRVCLEMANNIYQTITLVLSGIKAPIYRKDVPGFEDQEEPYGEEAKYFAESRLLQRDVKIILEGTNNNSFVGTIVHPNGNIAEALLCEGLARVVDWTIAIVTGGPAKLRVAEAKAKANKLRLWKDYVQKTSNRSKTGDNSSNSTSFDGTVIRIINSDLILVLADGNKERKITLSSIKAPKTKDPKDAFYNLEAREFLRSKLIGKRVHVNVDFIKPPTEGFSEERTCGTILLNDVNISEALVSKGLATVVRHRKDDDDRSMVYDSLLIAEDRAISQSKGLHNPKEPVPVRINDASETINKAKQFLPYLVRSGNLNAIVEFCSTGGRFKLFIPSQACKITFILGGIKAPKVGRTPADKSEPFGPEALEFVNRHCLQREVEVNIDNCDKVGGFIGTLFVVINGVRQNVAITLLAEGFVTIHEYSQSPYQKDLIAAEQSAKDSRRGIWSTIDPASLVKEEIQVFNGSLRDEKVPTSLKDVVVSELGDGGKLFIQVINDDLHKLEKLMKDFSLHHSSAQNTSFLPKNGDVCSARFTLDNNWYRAKVKKINPDETYLVSYIDFGNSETVNSSRLRPLDSKFGLNVLPPQSVEAQLAFVSVPELESEYGTEVFEHIKNLTENKNLRALFFGKDKNGVTGILLIDPKDESVGSIQERIILDGWGTVEKSVEKRFNLDLKNSRDLFNINKSNGKSVSSGTMFNVIENLMEAQEVAKKQRVIILNFFFFKIFKKKKKKCLVSQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX55</accession>
    <name>A0AAD5XX55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001286">
        <property type="protein sequence ID" value="KAJ3204572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX55"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47823">
        <property type="entry name" value="lambda integrase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="31589" checksum="38BB18246DB569ED" modified="2024-05-29" version="1">MEFLDEEILKLAKGEIQSNKIDTSSSSDEENHLTPSQVKSNQARQSQFNSYKTLAISKNWATNDNYFPINLTQLNSYVDYHIERKTKPQTLKAYLSVLSQYHYSKGVDFKNIEKDPSIQTKIQSISKKKENIDEKDSARENSSEPTIKNNSRKKRSSVKSNRHILKDEKLSPSVSNKKRKLVDIDSLSDESDSVGKTKNSNGKVTVNIRQKTKVKEDSDEKKKQNDFFSDSNSDLSELDEDEIEEKITSDRGSLRGIKKVNYAPPPLDPFKDKNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXB6</accession>
    <name>A0AAD5XXB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_005849</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000476">
        <property type="protein sequence ID" value="KAJ3216487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXB6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="99"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="198"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3216487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="291" mass="31530" checksum="73ADE5C76B60F032" modified="2024-05-29" version="1">MSAAPKVKDDPTTKMIKDFIAGGVSGAVSKTITAPIERVKLIIQTQDANPKIISGEVPRYTGIVNCFSRVASEQGEEIFFNDLNIKYVFRYSPKTDFWSFFGINLLSGGAAGAFSLTFVYPLDYARTRLASDVGSGKKTFTGLGDCLVKTAKGPKGIMGLYQGFGISVAGIIPYRGVQFGLNDTLKGLNPWDKEVSFRGIASKWLGAQLSVILSGFVTYPFDTIRRRLQMEAVKPLDEKLYKGALHCFSRIVKEEGASALFKGAGANILRGTGAALVLVFYGEAQAFMAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXS5</accession>
    <name>A0AAD5XXS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000999">
        <property type="protein sequence ID" value="KAJ3208358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXS5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3208358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="304" mass="34611" checksum="B090C53381262F63" modified="2024-05-29" version="1">MNLNSKNTNFLELINSSYTINTWSSNIFNTNLPKKHITTSYPSPPSVTANCVDKKINISKIMSEVDLALPSFIHKSNNERRQEELQEGFTTEYHLLSTNKRNCYYEESTYKFSSSKSNSCTSNISLSPTIGYQSNETSESAPKRKMQEKKDPLNVARDEKKLKQFACLYCGRRFSRKDALKRHEVTRSNDRVCASDGRGKFKNISLKTLQKDVNIIELLWAFVDTPKPLTLNLIFVIVVFVKLYLNYLKLEIVSSCKHVFKMCWKLLGTGTVAGCGPIEERGTVGLPWVDHLVENIGQTLSIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXY0</accession>
    <name>A0AAD5XXY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Poly(A)-specific ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PAN2</name>
        <name evidence="11" type="ORF">HK099_008468</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000930">
        <property type="protein sequence ID" value="KAJ3209636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXY0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06143">
        <property type="entry name" value="PAN2_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000028">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex catalytic subunit PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050785">
        <property type="entry name" value="PAN2-PAN3_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048841">
        <property type="entry name" value="PAN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028881">
        <property type="entry name" value="PAN2_UCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728">
        <property type="entry name" value="DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728:SF0">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20770">
        <property type="entry name" value="PAN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13423">
        <property type="entry name" value="UCH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="371"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="283"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="508"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="309"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="523"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3209636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1016" mass="114320" checksum="4982E17C1905D88F" modified="2024-05-29" version="1" fragment="single">MDSAEIIVLNKKKHIFCGSTTGQVFLRNLKTYEVENVIKAHSGSVANLDVSGNILATCGFSQRNNTFVIDPLVKLYDLKSMKELAPIAFPNGPLYLRFHPNISSVLYICSQTGILQKCEIGNANSNSFFLQIDLNDYASGFEISVSGDVLAFGDGTGVMYHWAKSADASYNAFSRPSELPNDPGTYRIPLDDNRWVLTFLSLLILSSPLNMVGLPYYTEQLLSNLPPGMLCNVGRPHPQIPEEVLKNVKMIDFVGYAPNPKTFKRNQDFNTFLKTKAYFEEDETPKFRSEQEREKTFGTPRKEHSYAPRSISRSSVRSTDSTSDLEVPSSPPSGGLLYNSFPKFYRKVEIKYSKFGIEDFDFGFYNKSHFGGLETHIRNSYCNSMLQVMFFMKPLVEIVKNHIQISCPKEFCLSCELGFLFKMLENANGGNCQATNFLRAFGNVPQAAALGLFEPDHATQKTSFASLIQNFNRFIFEQIHSEVLSVFNQLGVNVTILKNDEGCIKNECKSPDSATSPTDVIKANKHQKKLSKRKSKLPSPTTTYGATPQPSIVQQALALPLQSISTCNLNHQFVRETFIFTIDLTYSGKPAEKKTNKFDNNNGGHKESAIPISTINTSTQSPSSITFGDILQQSIQRETSSIKAWCESCSKYQPMQSSKYIKKLPLKGKPWVPFRTALILNSSNLLQVVSVPEEIDSLQLKLDLEKEHPNSVVGVFELQSSVIEIRHESDPAHLISLIKTYSKEDPTKVEWMCFNDFLVQPVPAAEAVHFKKWKVPAFFSYVRIDVEECLDFSGLPVRETASKIFQNELLNRRKNSFTTTVPLNLKELKKGYLCSIDAEFVVLAKEDTELRSDGTRAMLRPTRLSLARVSVVRGEGADEGVPFIDEWISTTETIVDYLTEFSGIKSGDLEISVSTHPLVGLKAAYKKLRYLVDIGCIFVGHGLKKDFRIINILVPPEQVIDTVDIYFKKNFQRKLSLRFLSWLVLKKEIQTGMHDSVIDAKTALLLYKHYLKCKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXY4</accession>
    <name>A0AAD5XXY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000627">
        <property type="protein sequence ID" value="KAJ3214374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3214374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="154" mass="17791" checksum="F90A0609F4B766B1" modified="2024-05-29" version="1">MLCRCLWLGCKESYRTEDETYEHCYTNHITKGKQVCQWVSSEKYGPCMSKMQHRGALKDHLISHFSFDFRPVECPVCPKKLRNRQELNRHIKTHEINNNITSNNIKDISDDTTNHNIPVSNSSTPQSTSNDNSSKTYSTPSPSENIMKIQNIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYE3</accession>
    <name>A0AAD5XYE3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MEF2</name>
        <name evidence="8" type="ORF">HK099_006185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000519">
        <property type="protein sequence ID" value="KAJ3215794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYE3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000514">
        <property type="entry name" value="Ribosome-releasing factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="38"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3215794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="823" mass="90866" checksum="60176646098949C4" modified="2024-05-29" version="1">MNWFAYCKSINSCFLKKNVFAVNISNSLRFSSSIVDSKKIRNIGIISHIDAGKTTTTERILFYAGHINKLGSVDKGSTVTDFLPQERERGITIQSACIPLGWKNHLINLIDTPGHIDFTMEVERCLRVLDGAVTIIDGVAGVEAQTETVWDQANQYQIPRILYINKMDREGASVSRSLKECSAKLKGWGKPLLCQWPIVLDGSARVNGVRRGGSGGAGFEGIVDLISWEKLHFDKDTFGTKIFKTPMAPSADLALCALYEESLQARTNLIEQLSDVDDELLESFLNEANGDPLKVRVIDIKNAIRRMTLSGKSIPVFIGASFRNIGVQPLMDAVVDYLPSPCERPHAAAITTTKDGDKVAKISLKNDQMFALAFKVTHDPMRGALVFVRVYSGILEAKSVLINTSQNQQKERATKLLQVYADDYEEITSIGAGNIGAIHGLKFTKTGDTLTNKINNKAITKLKEITLPPPVFFCSAEPYSKSDERNFEEGLNALIREDPSIRLSVSNDTKQTLIGGMGELHLEIALGKIFIYVNHIIVTMSLGRLRDVHKVDVRAGNVVIGYRESLNFDENFTQESSFVYDRDFLGKKAWASVTVQLKTLGDIETLRDHDEVKEGDGNKILINFEELGLSSFVNMANNKSDILESLKSGIQGAFSRGPFLGFSMTNLSVKVTRVEKHPISPELTTITAIRAAALRATQQAILKAAIVEYAQTNPFGKFGILLEPIMNVNIRIPEKYGGMVGRDLGGVRRGQILSLETEGEEISHNEFSRRIIKSLVPLSSMMGYSTALRSLTQGTGSFSMNISGYGLVNQDKLKTVIKVFRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYF1</accession>
    <name>A0AAD5XYF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS27_1</name>
        <name evidence="6" type="ORF">HK099_006466</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000056">
        <property type="protein sequence ID" value="KAJ3225633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYF1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.100:FF:000001">
        <property type="entry name" value="40S ribosomal protein S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_eS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_eS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_eS27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11594">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01168">
        <property type="entry name" value="RIBOSOMAL_S27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="83" mass="9155" checksum="0BDC9E98434C1813" modified="2024-05-29" version="1">MTLAVDLLNPLESTELRKHKLKRLVQNPNSYFMDVKCPGCFSITTVFSHAQTVVMCGSCSTVLCQPTGGKARLTGICLINLFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ00</accession>
    <name>A0AAD5XZ00_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003109</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000209">
        <property type="protein sequence ID" value="KAJ3221776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ00"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036435">
        <property type="term" value="F:K48-linked polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032435">
        <property type="term" value="P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903094">
        <property type="term" value="P:negative regulation of protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340:SF1">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="7">
        <location>
            <begin position="244"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="447"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="518"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="131"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3221776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="574" mass="65332" checksum="4EB590B1451C1EF8" modified="2024-05-29" version="1">MSDRETLLSFGFTTAQVNRALKETKNSGLQPALDWLDQHQDDDFSDEPEKTYSLASVSSENEAKPVENPISTEKEGGEISAEDLTAQSLQCGMVDDCGKLFKDGSAAEFHAIKTSHQNFSESTNQIKPLTAEEKEAKLAELKERMAIKRAEKLLKEKEEAKENEMKRRRTGKEIIEAKEKQQELEMKLALEQKKKEKMEDKIARDKIKAQIEEDKRERERKRLQEKEGYKQEAVKIAAPVVSNKNYDEARIQVRMPPGIPNLTNTFNANDPLSKVFEFVQSNSNLNSFKFVSTYPKKVYQSEVDSSKSLKELGLTPSSALIVLKENNLLSLPIQSESNANKIVYLVHLLDLVRFVQKEGVDHLNAAVFSLMSLDADEESYHIFENDYQDTVENIVRQFATGKKHKSLVTDVQNVVKPVIVTQTDVVKYFATFYKCNENLKEFKQLLIKKEIISLNRKSTALDGLKLMETNKLLAVPIVDDEGKFVHNFSASDLRGLTSETLETLKLPVLEYLKNNKRMGTTLKEILTVTTETTLREALDIITGNKLHRLWILNENSKVIGVLSLTDILRIFFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ80</accession>
    <name>A0AAD5XZ80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cilia- and flagella-associated protein 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">WDR96_2</name>
        <name evidence="11" type="ORF">HK099_006211</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000521">
        <property type="protein sequence ID" value="KAJ3215758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ80"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25828">
        <property type="entry name" value="CC_Cfap43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="6 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="59"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="140"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="464"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3215758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="572" mass="68146" checksum="A951BC354B35E4B9" modified="2024-05-29" version="1">MEEKRIQEEDRLKLQKQDNWAERALNQMMGGRLEDRSDQEEKEELVRPEWMNKPKEEMSEEERKLVKEFEKKLATFKEEQEKYKKALETELRKLQSSIVEVCENFDKSLNEFFNSKLETDQLIFQTELKLIKLNLSSVFSENDEAREEEILTRLEQLKNEKTSYVTEIPEIKKDLERCREEYEQVMKKDKEMDKIFKKEFHNYDFYFDNLMKLFKKRETQATLNLESDDSIQDHNKLVIINPFSQIEKSSVWEDPLPLNIEVDLPEGISMELWQKLVELRDRKIALEKEVFIAFNRFQEMQTLVQAVLDESERIKQETDVLTSDLNQFLEYKFHSTYNVENLFQLKQGQVEISQEPVVTDYSDAVLIHRGQVERLNESIAGLGKSKVDALKEMKEYRKGIHALEWENKMLDFQADDAIIRTRDIQLLRLTKQMQEYLRSGDEYAQTTEIIALEKRAEYSQKAHLHKLEEKNRSLHKLKKKILEKSTQNEDLDKELEGLEKTVKERNEIFQSSSKHNQAAKSDNNKLNEIYTRRRLVDLAKGQAQDIAILREEVERLRLRTYPAFSASKRRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZD5</accession>
    <name>A0AAD5XZD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000478">
        <property type="protein sequence ID" value="KAJ3216446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZD5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF17">
        <property type="entry name" value="SEXUAL DEVELOPMENT REGULATOR VELC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="31"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3216446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="214" mass="24514" checksum="FF76210ED9896456" modified="2024-05-29" version="1">MSKKFTSEKNSDSDKEIDSSKLLESTSRNMEHTHKYRLVVRQHPVHARLFGSSNKDRRPIDPPPILELLKMDHEEQLYPIIKDSMFFCMRVELWNSNGTSESCRKIHSDLPLFVGSQMENSRVLTDDLGRIGTFFIFKDLSVRDHGTYTLKFFFFDLESMESPGSLIEHSLTAEAVIFSNPFNVSTAREFSGVLQSSNLAKVFKSQGVKLSIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZN4</accession>
    <name>A0AAD5XZN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001516</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000143">
        <property type="protein sequence ID" value="KAJ3223115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZN4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="108"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="372"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="282"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="457" mass="50549" checksum="B46CBDF7572CF975" modified="2024-05-29" version="1">MAETISSFLIAAKRGDIRTANALLLEKPSVINETLSLTGANALYISCQNNHENILKLLLSKKNWNMQSTVNDGTTPLYIAAKSGHIRIAKILIERCSADINYSCQRNTFITPLHVACLSRKIEMVKYLIHSGCNIDKPKIDGKTPLITSVLLESVSLVKILLENGANKNIKDLSNTSALEYAKKLNNKTLVSLLSDVKKTTSSSGLSAGNIYDSKNLAVDIQNVSGVYYKNGNFLNKVILNLKFVAEIAVEKDTIATTDGSGCLRNNKSTVNKTIIPSATNKKPLVSGRVTSPTKSGLPNNRKLPNSNHPNSSKDILLSKNKPISETKKTSNLKATPAIKPFPIKRLPQKIFPLEKLNCTQQIIKKTNNQNLIFQKEIGKGGFGIVFKGLYKNKVCAIKKINLKLDNENKLEVLKNFLKEAQVMQSMKHENIVKFIDFDLESFSIIMEYMELGSLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZS5</accession>
    <name>A0AAD5XZS5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004293</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZS5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF3">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="534"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3228300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="637" mass="69750" checksum="64FEF1BB3B550DD3" modified="2024-05-29" version="1">MGFAILKPFKNFGPKENCSVQTAATAAGGLSAGFVSAIPALYRLGLLSTRVMDDFVTLLLWSLCAAYYGLFFAIPLRNYFIFKQNLPFPSPTIAANTIKSLHCSKAGELGAKKKAKILGLSFLFALVVKCVTWWVPVVTQWHILYYVGNLVNSTALQAADVVWRWRMDISLAFLASGMLVGMNTASTFFIGSVVSWAIIGPILFAAGVVNTAYGFPKYDTASASFATDDLSRKVSAQFWLLWPGVTIMIVSAFCELFAKWRMILHSFSGLTEIFKRSHNGDKLAKTKLFGKKEENNINDIELVDPNSETSRLVLEKEIEKEDRFAHAGDHHEIQDNTPAHEQVPLIWWLGGLVVSSTFTIVVLTVLFKVPFFQSVLAILVGFVLAFVGVQSSGETDINPTGSIGKTSQFMFAAFRTDDVNQMLRTNLVAGNVAASCAAQTVDMVGDLKTGYLLNASPKAQFIAQMFGSLVAVFVSVGLFTLFGTTYPCFLAPITTINATVVTKPCQFQAPTVASWTAVTLAVTTGISRTVPMSSGYFSLALTIFIIIFTIFKYKFLSKTQREYLPNLNGSLVCFFWKRRSPTSFEIFGFALASGFVAGEGIGGIFEAVINLSGFVQERDSIKWGIPPTSLEIDWFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZY8</accession>
    <name>A0AAD5XZY8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000687</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000117">
        <property type="protein sequence ID" value="KAJ3223794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZY8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12411">
        <property type="entry name" value="RRM_ist3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051847">
        <property type="entry name" value="RNA_proc/Spliceosome_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045844">
        <property type="entry name" value="RRM_Ist3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880:SF1">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="33"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="203" mass="23206" checksum="1ABE5821EE8EF181" modified="2024-05-29" version="1">MNKIRTLESINKKELSTNTSHDASWHNDYADSAYIYIGSLPYNLTEGDIIAVFSQYGEIVDVTLLRDKVTGKSKGGCFLAYENQKSTVLAVDNLSGIKLLGRTIRVVALDHARPKGERVEEGKEEEYKQRELQKQKIILPKRLRGDVSEESNEEEDVSYSEKTPDKKLLKILDDLKNCDPEDPLRIQLIKRLEKIKKKIAEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y063</accession>
    <name>A0AAD5Y063_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium-activated potassium channel BK alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_003615</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000239">
        <property type="protein sequence ID" value="KAJ3221288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y063"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003929">
        <property type="entry name" value="K_chnl_BK_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF10">
        <property type="entry name" value="SLOWPOKE 2, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03493">
        <property type="entry name" value="BK_channel_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="14">
        <location>
            <begin position="251"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated potassium channel BK alpha subunit" evidence="13">
        <location>
            <begin position="356"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="14">
        <location>
            <begin position="639"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="810"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="819"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF22614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3221288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="973" mass="110176" checksum="279E76AAC2856AD7" modified="2024-05-29" version="1">MKKGRSPLIAQGEIGGSIYDIESSKSFKFSPNLADRRERLAFYLDTTKFPWAETTDGFLSFYDSNLPYNAFKLQLADFILAIVLLVQHLPAVYISFDRVGTLFSLYTILTFAATIPVICAFAELDKNKLTYFGAGYWIYAYPTRFWRLKHSLSETLEPNKNFVFNLSSATHKGVHILVSVIVILVTVSAWNFNGMDVDIVPDNTPSRIATLAILVIGAIYVPSSLSDFFVLLKQQSKYDKPYTGERNTLFKHVVLAGNIVDVGALRSFLREFFCEDHGPQTITTKLVILQPFEPSDELQLTLNDVAYKSKVQYVKGSALSFRSLEKVKASSAEAFFLLTSKFGTDGDLESIDAATEHVLCIDSYKLGILSQNALAPGFINLITMLTTSFKEESKKEFLYKDPKANEWLEDYTSGLTHEIYTVRLSIKYRGQLFQNLASYIYQKYNTVLLGICHNSNDSYELQISLNPINYVVEGDELTYLITSEKFLADEIANGETFCGESFITDFNFKDILSLSDLEECDIADDLNTDDVTIDIPHDTEETPLLENFSSAEKEFVKDATDEMIYSENVERMRQNISGAMKKCHDDSKFDLVYRGPKIKAGDVTLNKTGEPASLKFLSNLTQDSTFYNPENIQFLPENVKDHVLISTETNTDSVKYFVAVFRHKDPNTPIVLLSTEKPGDGLCEENDDNSFSNQSWKYFETYSNIYHVSGTPLKRKDLIAAKVENISSAIILCDPFIYESGNLLAEAAALHSLLSIEEMSPKDVFISIEFVHEENMKIIGKDDFDTGPRQSTLENFGAIATPSFIGGAEPFHTDAKVQGSPSHSPSHTRNSSFTEVNKLDSQKFSDHGNIYQIELPKKFKEKILKIEKINATKTKKDQLKFKLERPKKTNFLQKFFPNNQKKKHEHTKSLKNLRYIELFQFLLTKNCLSLALYRQSKGAGVSQRYVVLNPKSDTELRSDDKIFVLSRFKLVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0J7</accession>
    <name>A0AAD5Y0J7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Elongation factor Ts, mitochondrial</fullName>
            <shortName evidence="11">EF-Ts</shortName>
            <shortName evidence="11">EF-TsMt</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">OCA1</name>
        <name evidence="11" type="synonym">TSF1</name>
        <name evidence="14" type="ORF">HK099_003987</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Putative tyrosine-protein phosphatase required for protection against superoxide stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein-tyrosine phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000270">
        <property type="protein sequence ID" value="KAJ3220831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0J7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14531">
        <property type="entry name" value="PFA-DSP_Oca1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000035">
        <property type="entry name" value="Tyrosine phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="entry name" value="Elongation factor Ts, dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020428">
        <property type="entry name" value="PFA-DSPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF8">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE OCA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01911">
        <property type="entry name" value="PFDSPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="Elongation factor Ts (EF-Ts), dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="265"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="13">
        <location>
            <begin position="12"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3220831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="670" mass="76244" checksum="0D0AF3BBA4E31801" modified="2024-05-29" version="1">MHFSQHLIPPSNFGLIEENLFRSGQPNELNFPFLEKLNLKTIVFLAPEDPNPKLLNFIDDQEINMHHLGTTTVSNAWDPISEEIVIEALGIILEKSNYPILIMCNLGRHRTGTVVGCLRKLQKWNLTSIFEEYRRYAGPKVRVLNEQFIELFDIDLVRIPISSPIWLYIVFAFNLKAKNRKYKFITITVICITVIEYLTDTFNRFLFQTKNEAVQTLSSILFTTVVLSGITFDLYGIFRMIKVSLAYEFIRSKTVRDRMRRYKRLLFLLYFGLVMLDLLAIIVYIFPILIPLQDAFAIQSIPTVMISLHGFGALSIFRLLKKGGKYFKADSDASNFAQSAEVDLKLVSKLRSETNCPLSKARDALLKSNNRYEEALNWLESDQKISGAKKAEKLKSRVAKEGLINIVGNGNKKIIYELNSETDFACKSPIFLELLEKIGTTAFYFTEDLLNDKTALKIQEINVEKLFNCPVMSSTDSNINLSITTGLELYRLKEEFFKSVGKVGENINLRRIFCVNLPAPDLLSNSLYYVGSYVHQSHNSPVGSGRIGSLIVLEAKKCKKFVFNAESFVGFETGSQLLASKLAQHVVALNPLFLQKESTDLSNDNETEDNALLDQDYFFGGGKVRDILKVGEEDFVEYKILDFIRFECGEGIDSDTSNFAEEVLNFAKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0S9</accession>
    <name>A0AAD5Y0S9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000241">
        <property type="protein sequence ID" value="KAJ3221250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0S9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="67" mass="7670" checksum="A26B1AB852DBFBB4" modified="2024-05-29" version="1">MKQPRLPNAHGVTDSGLQTQEGLEEVLRKYLGENDEFLIGKAVPDLLCENGIRCRTDIINKIRRKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1H5</accession>
    <name>A0AAD5Y1H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003328</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1H5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000165">
        <property type="term" value="P:MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06606">
        <property type="entry name" value="STKc_MAPKKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF48">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BCK1_SLK1_SSP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="836"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="513"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="578"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="865"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1171" mass="133980" checksum="4509177D9B79ED34" modified="2024-05-29" version="1">MRKFSNEIEHNLKVDTTPRNSETSEYYFKFNMLPEDINRLSISSSQFFELLKEAPLFSKIPKIKNKLIVPIDLRSFDDFKEENLIYSLNICLTPIIIKRFKQNILNEFHFDRFLTSPESKARLQKFQEYLKLYKDIEVIVVIFDSDMSLNSSNNLFLNENVLILKEIIENVMLKNFLDLSIITNDVADINFVKKSYKYFFLKNGLRNFFKCEKNNLIANKFITKINVAITEEQEKNLENLFNIDEKEESAVSKRSKKFIKQHKIGNGAFGNVYLALNVETNSLMAVKEVILSGNNLSESQNLNESTAEKKLIKAIKNEISILRCLKNENVVNYLDCEITKNYINLYLVLLDMKGVLKISDFGFSKQLDKSKNPYEVRESPGIKGTHRCIIIKYVKQVLKNVILDMAPEVLENIVEESYKKKRQNKKSLEPNQIKKKNNLNSEYEYSLDSYSSLSVFSVNSSISTTPNSKSIINSASSIDNGFFPPINLNQSRINLKTSPSRNLLTKSASFQVTGERAVSSARDSRTRAQSCASDRLNSAGARLEQSLNSTRLSPIKRSSTIESHLTPSPPKEDPPNAITETMSPPLFTSTPPSITLERSPNFASSPRRQKYKIHSTSVPAAFTKVRPYLIFGQDSVLSSLTATDDLKNLRVTHLLSVSDAEPNFAVEKNGAFQVFQKVISDKVNSFFEDLKECCVYIDNALKCDTESVVFVYDKRGTYHSALVAIAYITWCGKRALDAFEEVRLLNPEIEKTLVNCISQLDDFVFNNLYHEEDDDPSTSFYEEHLRNRPSVEYIMKNLENFFPLSETKLEVENEKIIQSYNLVQNDSVATKIKWTKHMEDCIGKGAFAEVFLGLNLVTREIMAVKQVRLSKSPGEAERKHINAIKTEINLLRCLEHVNVVKYIDCEINNEYINLFLQYVSGGSIGSILKKYDKPFPEQVVMFLDFQIGNGLAYLHSKNIWHRDIKPDNILVDADGKVKISDYGVSKQTIDQDPYVSTDSVNKVGTFRYMAPEVVCNRGYSAKVDIWSFGCVMLEMITGQKPWSEFRRQEEISRALLEKRRPSISNKLSKAAQSLLDQCFNLDSKKRPKAVELLKSQFINQLKNPHLFDLTSFFSEAEENFKKKKKKDYEDENEIIIEGSLLNPFSNSGKNNSFTKDKSNFSFPESFNASIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1L6</accession>
    <name>A0AAD5Y1L6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000163">
        <property type="protein sequence ID" value="KAJ3222698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1L6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="473" mass="55880" checksum="7C2DCD78E1DC0FBB" modified="2024-05-29" version="1">MNINENLHDLPKPIDPQLMEFPDEFSSEDDNFIETYNKFSFSNSNERKLKLEKFKSNLNNLKTLNENMLLSKKYRLYKNLIIDFENFQSLYPALTGNQILLPIFQEWYKPYKKPNSYKLNLNTTFPQDLACFTPKASDICRSQKEGFSLGRKGETEIKNFISNDKYIVEEVLNCRKVIHKPNMCISSSTLQHLILTLIQQKTCFPVVVSQYYNENSQSLEKVVYVDKPYYKKTKHEIEEKQLKAAYKRFFFAKNVIPAQETVNEESLEKNYYYTRTQFADLKVLVRYQLEGILGDDLFGLKIKKSSDRHEFTKKERLKFWMYDVIRPSLNSKVGFTTEIGLFMFIQNPSQKGVLFLGRIENYKLTYIDHCKRKNFIKDSSEFEPHLQRLYFILKQLNDLPIGNYFINCDTDGNFVYKSLSEEELCNKAYDYDFDLVNFMVNGSGRIDNKNKSKKPVIERTAYRKDDVIEEGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1V6</accession>
    <name>A0AAD5Y1V6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein ERB1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Eukaryotic ribosome biogenesis protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">BOP1</name>
        <name evidence="6" type="synonym">ERB1</name>
        <name evidence="10" type="ORF">HK099_001340</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat BOP1/ERB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000137">
        <property type="protein sequence ID" value="KAJ3223249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1V6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03027">
        <property type="entry name" value="BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028598">
        <property type="entry name" value="BOP1/Erb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012953">
        <property type="entry name" value="BOP1_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08145">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01035">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BOP1 N-terminal" evidence="9">
        <location>
            <begin position="92"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="355"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3223249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="630" mass="73253" checksum="57ADB397C4222778" modified="2024-05-29" version="1">MPKRKLLKNEEQMDNEEIEILPEIIESSDDEEDHDNDTENDLTEHGNTSFDENDENDWYYNHKRPDIIPDYNSDTSDEETENTVGNIPLEWYADFDHIGYNVSGNKILKPASKDELDKFVDSMDNPNSWKTVFNELEGKNVVLSKGDLEIMRRIQRNEYPEKDFNPFPNSVEWFSSKLQIHPLSSAPEPKSRFTPSKWEAKKIMKIVRAIRNGWIKSVEEKKEMQKPKQYAIWDDVKDEEKLDKMHIPAPKLKLPGNNESYNPPNEYLPTREEEEQILKDMEEDKLLFVPKKYDSLRRVPGFERFIEDRFDRCLDLYLCPRTIKKKINVDQESLIPKLPDPKDLQPFPYTLSIIYKGHTGKVRSLSVDPNGHWLATGGDDCSVRVWDIATGRSMKEYKFEKNVVNVSWNPSKSLSVLSISVGSQIIILNPGVETDIVNRATNEIFNLESFSESKKLPEAIWRKPTEKEFNLGFRVIIDFKKTQRYVRVYDMMQQKLVKKLMSGVKLISSMDIHPQGDNLIIGSFDKRLCWFDMDLSSKAYRTLRYHQAAIREVKFHKKYPLFGSCGDDGKLNIFHGMVYNDLMHNPLIVPLKSIFVGKTEDGLGCLCFDFHPSQPWVFSSSGDCEVKLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y268</accession>
    <name>A0AAD5Y268_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000074">
        <property type="protein sequence ID" value="KAJ3225000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y268"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="29"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="311" mass="34815" checksum="E6706329180F4ABE" modified="2024-05-29" version="1">MPTASIGKRRLPSPFNMYYEITGTGPIKLVFINGVGGNLNGWEFQISYFGNLPDYTVCAFDNRGAGLSDTVAFQRNTTKEMAQDSLELLEEIGWTKNINLVAVSMGGMIALELALLKPEMFATLVLTSTTSGRSLIPLYGLINLPRTLINKPEKSIEILAGVLFPQSFLESEAPADFVPLLIPTKEKYTQRDVFWETMARRSTKSRAATLKGYLLQVGAILTHHVSKERLHILRDSGIEILVVTGTEDNLVKPENSEYLAKNLNAKLIVFEDAGHNPHNQLQKDYNDLLEEFIFESFKKKNIKIPFFIANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2U1</accession>
    <name>A0AAD5Y2U1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositide phosphatase SAC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">INPP5F</name>
        <name evidence="2" type="ORF">HK099_005263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000040">
        <property type="protein sequence ID" value="KAJ3226266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2U1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045334">
        <property type="term" value="C:clathrin-coated endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001135">
        <property type="term" value="P:regulation of endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="1">
        <location>
            <begin position="248"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="571" mass="65799" checksum="DB4E21CB9092B074" modified="2024-05-29" version="1">MLKEKLHIAVDKDQFFFIKQNIIGEFTKIVTLNFKSRLTRNFNESLEFSLKKYEFFGIIGIISLDSGDHLILTVKRENVGHIKSNSVFRIDDILILPFNELADIILARYTNNVELKETTKVSNVEVKSKPVNDQLNSKFDAILKKNNVVKIVSEKERSNHFGATPTKKTVISTLTEVSSAVNLGIKKSFGYNLTECKISKPNFSKDSSFTLMQNAISLTSKKVTDTTKRVIGDENDGENFEELLIKEITRLLTSGLYFYSKEIDLTNSFQRQSTFSDKQNLFLNLDKRFFWNEHLLDTFIKQNVEDFIIPIINGFVQIESLQIKGLAFDFVLISRRSRDRSGLRYERRGTDEEGNCANYVETEELIFYQNHVACFSQIRGSIPVLFHQSAQSLKPIPIIDGNDDDSERALLSHFARQTNLYNKVICVNLVHQQDNRESIVGSKFKSIIEKLNIPQVQYNEFDFHEHCKSFNYENLSILLNIIEGDLNEQKYFWSENDVVFSKQEGIFRTNCMDCLDRTNVVQSLIARTTLKKILFKLGIQSPDCAEDENLENIFKTIWANNGLSNLVPFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y334</accession>
    <name>A0AAD5Y334_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rotatin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000053">
        <property type="protein sequence ID" value="KAJ3225766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044782">
        <property type="term" value="P:cilium organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030791">
        <property type="entry name" value="Rotatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31691">
        <property type="entry name" value="ROTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31691:SF1">
        <property type="entry name" value="ROTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1833" mass="212883" checksum="63DCF03D688CAA7A" modified="2024-05-29" version="1">MELVKERISSHLDTVRWRAIESLKFKLKSKNITPNDLIFENNLISTLLEELVACGDEKKINTLLLIFLEISKTSPGSKLLLSLNFINILNALQEKHINLPLIKDTLSVLLGSKEFDIDTNLTLSVSRLKYGSRYKVRETPIQRVEVDRRSRSVSPSKYNNIQTRSISPFKSLEHKPTAPPYIPNRFPTFDQVFLSPIDKQIVENFANFLGKNEVEHKELELFELIIADFGPQIFLQKSSLFRLLLMGLDSDNNLRVEANIIYLNLLCCQWGTMLRKSLDNMTFYSKFTSNTYLNTLNASINIGDPPFESNNSSHGEYSISLMFASSEIFVKLLPLLRISCFVPIILKVLYGLMPYLHVHIDSILEEFSQFDGFANHYLNILFEVINHYDFKTEFYDEREKEFVSLMVKNSETIEILSLLLGHRNKWVQLNAFKELEWHFAEIMNVQNKESEICNKFFQTTLNLVITKGIPNVNPEIKTVAISIIKVVVENFKNFKKYSIDILTLLTFLQIFFQKDTSDLFYNTLRICEEENLFLTHLEKCKFYLRGLFHKNETLREYCWKILDKVIQESSHFPLDKGWNCFLFPSEFLCENLKESLSTDEIEHEIILIYERRIYELGISQLIINFFCSNDFNLEEQKETVLIMLNVFQSIAEINAHFCYQINIFHQDKIVRYSLARLLFLILFDIRYQSIVFSSKTLFGLQNERNPVVEQFILENFQTFGKTTVRDNEYFEELHDIIMDSNLVQENFSILMLMECPISIETSSILDLFNTSLKNLKIAKSHLEFSRNLKYLKEWTLCRSDKYIISELGIQEVFQKEPVSIDDLSILEEILVYLKEIINCKNVFDVFKNLILDCFPKVLFEIINPSSENTIYSLNLQAKLSDTIISLLLQVFSMLEKDEISDFVLNTNCLKILRNYTVKVFSDSEKIDNYKPKGLNFIQLLTTLNYVVSIPTLVTIVPGSVIAQTTDLFVQLITVFQRKFSGFSNGDGFRTAYKWACLNLRNISRTSVCFSDTYKPWLWGDHWLNENSLEWLIVMLNDDENKIQKIALGILGNLILIKGSYTFVLDKIPQFLDMAFSHALNFECGFAVRQESLAIINNFVITYCNDHGLKADEVNFNKSNVVDMNSNSENIKRLFLVFENSGFFDHMESLLTKDSLILSYKCILTELFLNLAIISPNTIRKKFLHGNNFKLFLNLYFNWNEIELNCNTKGEKNLEKDMKFLNIQNFFKFFDEQDLNTIFNMHIPQSLMNFKAKQNFVLDSHLNFEFKLKFLKIVWFLIKGDGLDAIEVKNFLLLETEFFNLILKICTAKIDADGPSSLRIHYDLDLIGLGFVIFGNLLNLTIENSKESYNLEKHLKKSVSFQILTNLSFLIFYRGEEMVYLNSSCQLLGKLLSYHFGEVYDLEIDKIFLEEEGIKLGRKLVVELIDILLNEDNLEDNLTMESIRISLQCFFGKCGFAKEEAIQINLPGKFISRINNKWTLHSVKLNEVIQNELFVITTLLRHLMAGSAEGKLLCKENRVHELIFDLLSNKELALPLMLETLACLNNFLANCNENKKAVLRYQRKSTNNMQCGKSEKSLDYLEVLLRCLKNNEAEGIFAGFVDVLKLLSLHGESKNKILKSNFCLEIKDIFRKVVKNKEWVKVGQILKYYSNIASLREGQLILLKMDGFLTEVIKLLDCKSTSIRVDSLRLLRLLSYLRESKSYFLSEVMILIPVLNTLLNSKSLKIYSLSTSLIWCLLYDSEKSRFLLKKYNIMEILNNFVNQLEKDFGVKLKFEGIINISNIENFQDSSSKENTNIITIPKQNETSVKAFNASDYECLCETAKNLKVIKQLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3Z9</accession>
    <name>A0AAD5Y3Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000051</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3Z9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="5">
        <location>
            <begin position="280"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="386" mass="43969" checksum="CCC8A181C8FB7A07" modified="2024-05-29" version="1">MKSQASQDVIPVKIVNMLPSYQDSCNSPFQQEYITSPDVEQDSFNLHRRFLKAPQFQENLQTDTIVIHNSHSDIINEVGANPFNQLSSNFRQQNSGLYLPTLEKSSIINYPVRQHSTQLLSQEHHHNTHHVNDNTHANHNHKTAEALLDKILYACDTMKKVVLANKSILLDTPNSILPTEPLRKIYAKTYDTYQLLSSLSFTHHPVDTSLQNFQSHSQNKISVNLDNKFKDNSQNVSEDMDNEKIYCNKGSVTTGDLRQTNSVKKRRRGAQARVGALGVCHSCHTKDTPEWRRGPDGARTLCNACGLHFAKLMRRRNKQQQTDSMVKGKDENSTKTFKDVLKEFYSNQSVVNMKNSKKSLTCTEVNENSENLLKEEDVNVDILSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU28</accession>
    <name>A0AAD5TU28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Glutathione reductase</fullName>
            <ecNumber evidence="3 16">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">GLR1</name>
        <name evidence="19" type="ORF">HK099_001638</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 16">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 16">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 15">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="3 16"/>
    <dbReference type="EMBL" id="JADGJW010001487">
        <property type="protein sequence ID" value="KAJ3203027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU28"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000003">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000235">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 13 15" id="KW-0274">FAD</keyword>
    <keyword evidence="5 15" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="18">
        <location>
            <begin position="9"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="17">
        <location>
            <begin position="358"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="143"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="179"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="14">
        <location>
            <begin position="47"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3203027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="465" mass="50812" checksum="09841F93FECAC6EE" modified="2024-05-29" version="1" fragment="single">MAVITNAFEYLVIGGGSGGIASARRAAKYLGPGKVAVVESNRWGGTCVNVGCVPKKIMWSTATIAETLKDAKGYGFDVENKGHNWKALKEKRDAYIQRLNGIYKNNLAKDGIAEINGIAKFVSKNSIEVDGKVYSGKKILITTGSSAWIPEVPGAREYGITSDGFFELEYLPKKVAIAGAGYIAIELAGIFHHLGADTTLFIRHSSFLREFDEIISDSVMEEYRASGMKIVTLSNLKKVENRGTNAKKTLDFVVDVKDESGTVSTKTFEGFEEALFAVGRNANVEALNLENVVPEIKFNSKGYIVVDEYQQTGQESIFALGDVCGKAQLTPVAIAAGRRLSDRLFNGKTDRKLDYDNIPSVIFSHPCAGSIGLSEKQAIEKYGKENLKIYQSKFTNMYYSMTDHKEKTAYKIICEGKNEKVVGLHLVGRASDEILQGFAVAIKMGATKEDFDNTVAIHPTAAEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU69</accession>
    <name>A0AAD5TU69_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001430">
        <property type="protein sequence ID" value="KAJ3203442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU69"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042104135" evidence="1">
        <location>
            <begin position="18"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="79" mass="9153" checksum="C76FEE67923D8D23" modified="2024-05-29" version="1" fragment="single">MKFNVITSLLLVATTVSFPQHQIPLGYNQELRLIRTSDEVDPIWMSEDETMDLIKNNVKFFDVTDGYLDLEFTNSVKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUL9</accession>
    <name>A0AAD5TUL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000873</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001219">
        <property type="protein sequence ID" value="KAJ3205269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUL9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3205269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="221" mass="25701" checksum="A9F491D403EE8E5D" modified="2024-05-29" version="1">MSTNNLVNEKLDDEGLITYTGSKSNLSKRKAKKISKEIDEELKRELEREIEKGRKLLILGSGDSGKSTLLRQMRLLYSTGFDEKEKLDYKFIIFKNILTNLHKLIFVAEKLNFNFNKQQIEIIQKIKTFENEFSGEIPPSIFSAIMELWAEGKLKELIKVNNEYNIQDTASYFLDNISRLMKSDYIPTDQDIICSRKPTLVITETVIKIQADLYRIYGKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV28</accession>
    <name>A0AAD5TV28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000991">
        <property type="protein sequence ID" value="KAJ3208506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV28"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3208506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="59" mass="6260" checksum="0340C8EC2929ED22" modified="2024-05-29" version="1" fragment="single">ITKTMNFEKTEDGNVRCVEISGVVAINIEGLTSDSWIIEIVNLGSGVATPFTGTTEPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV31</accession>
    <name>A0AAD5TV31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutamine amidotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001162">
        <property type="protein sequence ID" value="KAJ3205971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV31"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="1">
        <location>
            <begin position="65"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="27810" checksum="46C00E2F48C1A2D0" modified="2024-05-29" version="1">MKFALLKCDTPPPPLLPLHGDYTQIFNNLFENVLTHQKHLLKLNDSNIQCTSFDVINGEYPSNPEQFDLIVLTGSKFSSYQNEPWILNLKKFCKLVIEKNLSKLLGVCFGHQVIAEAFGGKVEPNLAGWEVGWTDIKLNDFGISNFGKENMKINSMHKDHVTVTPQNFEIFSYTDICPNQGMIGYNNRVVTIQGHPEFTPEFVTALVKLRTGIIFDETFANKVLENSSKDLDGSWFTSNALNILFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVJ4</accession>
    <name>A0AAD5TVJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptide hydrolase</fullName>
            <ecNumber evidence="9">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LAP1_4</name>
        <name evidence="11" type="ORF">HK099_008681</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000984">
        <property type="protein sequence ID" value="KAJ3208630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVJ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03879">
        <property type="entry name" value="M28_AAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000042">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041770892" description="Peptide hydrolase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="10">
        <location>
            <begin position="161"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3208630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="361" mass="41124" checksum="A3AE08346172FEB7" modified="2024-05-29" version="1" fragment="single">MRPAILSTIFFVSFISLALNSPLNNQYLLTKENLRLISTKQNHAEWLNEIQILKLIQKGIKFIDVTDFVEYNSPLNTAELPAKLNQDSTVQELIKKIDKLYMKKFLTTFTSFNTRYYRSKSGRESQQWLLEQLNLLKDKNKNEKVLLSVTEFEHTWGQNSIIFQIKPIENDDGVVIIGAHQDSVNQWNPWFGRAPGADDDGSGSATIIEALRVILHGGYTPKKVLEFHWYSGEEGGMLGSQKVAAKYRKDNVAVVGMLQVDMTGYVKSTKKEIIGISTDYMDPKLTNFLQAVSKRYCLIPWGDMKCGYACSDHVSWYNLGYPAAFTTESEMKDSSPYIHTTGDTVDTLNFNHMKEFVKLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVS2</accession>
    <name>A0AAD5TVS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000989">
        <property type="protein sequence ID" value="KAJ3208544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVS2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="568" mass="60395" checksum="97B3C9998CA05841" modified="2024-05-29" version="1" fragment="single">MVIDNIDPLTVLDFTASNIHLSNLHLVKKSKIYVPTYNSNNNNPKYVPSYLNPTTQKKKSNYFYSNDNKKTYPSYSYNSGSNHGNNGEMSSGSDDVSGGQNGNQNGGGQNGNQNNQNGNQNNNQNPNQNSNQSGGSGQNSNQNGQNNNQNGQNGNQNGQNGNPNGNQNGNQNGQNGNPNGNQNGNQNGQNGNQNGQNGNQNGNQNGQNGNQNGNQNGQNGNQNGNQNDNQNGDSNNQNDNQNGDSNNQNDNQNGGQNGNNPGSGTIVTNSISLSVNTVSSTVTPTSSPPDPSLAVTSKVPASITPINTESSGAASSANATNSNILPVILAVGAFLIALLAFLIVFCFLKKRKRETGLERGIPENSLHNQPVQSNVMTETSATSSPPEVPPVTFYAGDVFEKRATVHSVESVKSKNSYLGEMSTFNFNAGDDRYNLLSQSISVLPTKDVTEDLMSNLNLKTVENETVSVSHHNSNLSSGEVADKSDIGVNEASIPETVPPTSLTEAVFVIPENEVPKPVIEDTETEKNISIPTIVPVAITTELNSNKNIEKKKATETAENVSRPSENFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVS3</accession>
    <name>A0AAD5TVS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Indoleamine 2,3-dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008483</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000934">
        <property type="protein sequence ID" value="KAJ3209552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVS3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033754">
        <property type="term" value="F:indoleamine 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657:SF5">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="253"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3209552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="339" mass="39185" checksum="ECC0B5248AF3ECB4" modified="2024-05-29" version="1" fragment="single">MPEQISSNPKIPTLFDHGLNSKTGFLPRNNVASIALPNFYRHWEYLFENLIPFIRDRTIRTKILELPMFTVDNLETEADWDRAYLVLSFLGQTYIWGDTVNDEVLTKLPINISVPWCYISNRLSLLPIITYKAVEHFNLVVENPDKPWDISNLSMKYTFTGTYDESWFYLISVAIESEGAKAMQPILDAIDAIEKKDHKTIHRALKILIEVLVELAVILGKMHLHCNADIFYNRVRPYQTGWENSKHHPEGVYYEGVPDQTSPPVPKEGLPKKGSYQKYAGGSAGQSPMIHFLDIVLGVVHYSTKKPGEETHKKSVYIYEMRKYMSGKQREFLRRLEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVX3</accession>
    <name>A0AAD5TVX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000810">
        <property type="protein sequence ID" value="KAJ3211852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVX3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="299" mass="33707" checksum="6A1D569CA4A5F1A2" modified="2024-05-29" version="1">MVNLTIDENKKNLIIHLSVFQKILSVQGDLIIPLKQIKSCSPSTQKPPLFNGFRNYQKLNSNPTYGAINIINPLTTNSKNSDQNSLNSSQNSLNSDQNSLNSIQKNSTKNSSNSLNSATLKKKKLNFKNLKLIPTQADSLKNKNSKTKLIPLKNDPNLNKKNNQLHKKNNSNKLNQSSKLFIQQMFGKNVDFNLIIDLFQQYQFQLALNKKSSSPVLYSPPRKFGKLRTKSTKTENFISTNDNKLNKNFTQQQQPATPSSIFAKLDLLDSKNTLEKNENLSTFSTISNLNNNLLVSCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW39</accession>
    <name>A0AAD5TW39_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000875">
        <property type="protein sequence ID" value="KAJ3210752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW39"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3210752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="24202" checksum="98FA87958DE6BEF3" modified="2024-05-29" version="1">MKTYGVQRDLIQEEIFDKIGMQETKFWENFESFDMLQNLASPSINLDGKPTNIFVEKENLTHYLKCEPIGITTTCNDLTKWMQYLLKNEDQFLKLENFYTKEEETHLVVDDHGNLDYLKGGEKVTKSTLNDLVEEWTHSGFSMGYTSKARIFPQFNFGVFVVSNCLSSPLPELVSSYIIESLFDLPIEKRKFNLNKVLNELKILKSWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWA0</accession>
    <name>A0AAD5TWA0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_008059</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000849">
        <property type="protein sequence ID" value="KAJ3211193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059033">
        <property type="entry name" value="C144_05_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26021">
        <property type="entry name" value="Ferritin_C144_05"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="307"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1367"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="708"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1372"/>
            <end position="1382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3211193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1432" mass="166652" checksum="56A0AE2CBE2E005A" modified="2024-05-29" version="1">MNKVDEEDFYINFKNLSHCLNKSGKRKLTNDKKNSVFLNNWKKVINFENDLFFIENFTFFQNLHSIHLLLDTIDYTEFDLNLAKDNNKIISFKLQIDDTLNNIKICLNHNLIDINCFLNLNVIEENKFKCEINFEIFLIKKWLGLENELISKLLINIIEPKILSKNTNLLNNGLITPKKYNLNPHFTQAKGLNPTLLPYQQRAVSWMLEKEGMKFEETGAVVPMNSLEEPDLPFFFERHSTEDGECLYFNRLTGYVSEKLPKNAKRSNGGILAEEMGLGKTIELLALILLNKKEGLEITQQPSTFKSEVCLYCNQDDDGNIKKWKSKDTIFNVARINSILKCEECNGQFHLRCSDFKLKNNFLKSTSIFSCKFCREKSKNDEIFDSKSTLIIAPLTIINQWKGEILTHTQLTVFVWTGDIYEQQLLTPKILGSFDVVLVPYNAFKGEIHAAKPISDRRLRKNSKFPRRIKWWRLCFDEAQELESSKATAELAEIIPAKYRWAVSGTPFGRNGLEDVKGLMDFLLLDPLPWSKLTKCLEKYPEIFNPLFFEILRSFLHRNNKKSVENELILPLQTQTTYSLQFTKAEMHFYTLIKHECQKELSELGCNNFDDLEGFSLEKRKEILSVMRLWIRRLRHACCHPQVGSYNKNELRKTFKSISEVLATMISQGKSMIVNLKRNEFILLISKAQTFEFDKDFATAINIYQNLVLKCEKQILEFTEEIVEAKKQKINLQNLLKEANDKNEELRTLIHQRKNSLLDAVDNNDSDILKYEKNLAYIVELEKALHNLTSREVTLINNERNWKEVLHKLFFFLGAAFHFLEEKKNEDKYYELAEKLRLDILFPTITKVQSSIKSLKLYVNKVNVQIFDVPESLKKNKNSFTEAKNYGGMYISNFSNFKGGIKSGIIFEEIAEIIEMLDLQWDVMNKFRDDIIRILVTEIEPDKETVTGEEYDQGLEHQRLVEVYQDVYSSSLVQRFKLLTGEIIPKTSKIFELKEERKMFDLLKPFNSFKNLRNLINQLKQISLLEVGKLPKVEIEMCAMASTEFKKELDKQLKKYEILDRENQYFNSTFNIRVNYFKNLQTLSDGVMEVEVPPLEKRDSRKNEIQKELNDLNIDMNGQIGHLRYLETLLNEEKERENGTRISSDASSIQNCQICKSLIDECITPWILKKRKCPLCRQPCKIDDMQEVNFNELVKNVEVKEVNYEESKGCEKSELKKKIGGNLLTEEGNLNLLITKISEVKIKGSFGTKLDFLLKHLLFLINSENFLESADVGVKILVFSQFTEVLDIIAIGLSENKIHFVRLDGNKKEKKTAIARKKGQGGRKRKKMNQNVIPLEEILNFLSQPNVNNFKNDVAGDFSDNIKKKKKKISNEQDESEEDEQELNGPTTNLGSKKMEILIEIEGFCLEFGRISEASDLFRIVKKEFYNVDYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWF6</accession>
    <name>A0AAD5TWF6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">POLR2L</name>
        <name evidence="8" type="ORF">HK099_007925</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000814">
        <property type="protein sequence ID" value="KAJ3211781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWF6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00250">
        <property type="entry name" value="RNApol_arch_Rpo10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3211781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="61" mass="7096" checksum="3C5C22DF443DE68D" modified="2024-05-29" version="1">MIIPIRCFSCGKVIGNKWEPYLALLQADHTEGEAMDQLGLKRYCCRRMVLTHVDLIEKFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXA5</accession>
    <name>A0AAD5TXA5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_007263</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000690">
        <property type="protein sequence ID" value="KAJ3213648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXA5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140824">
        <property type="term" value="F:thioredoxin-dependent peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17330">
        <property type="entry name" value="MFS_SLC46_TetA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000010">
        <property type="entry name" value="Glutathione peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF117">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="1"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3213648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="539" mass="60113" checksum="3ED57F2E74FD5E09" modified="2024-05-29" version="1">MVKDFQFEENEIGRYSGYLLSSFMFGQLLFSFFWGKLSDIIGRRPVLLSGLILTSFTCLAFGFSSSYKMAIIVRFITGSVNGIMGVSKTYLAEICDETNQGKGFSILGLNRALGLIIGPIIGGYFSNPSKKYPQIFPKGSFFDLNPYSLPTVIAFFVSIMCAVAAYYVLEETLNIPQPIKLHDEDERDVLRSADTFEEYYSVVDCSSSDSPTVRSSNERISNETTPLLPVTEIDSVALLDAKPSLFVLLHDKGIAVTLLDDESFVLWARLSKENGGIDWSSSEVGTAFSFGGIILLFYQFFVYPWVEKKIGILKAFRVGVLMTVPAYIILPRTSYLLDANENAKVFNEKTWVIWALVFFCQALRSISSLQAFTSVFIMVANATPANSLGTVNGFAQTLGKPFPFSALKGKPVLVVNVASKCGLTPQYKGLQAIHEKYHDKGLQIIGFPCNQFGKQEPGTNEEISTFCEANYGVKFTILEKIEVNGANTHPVYKLLKDQTTKEDISWNFEKFLVDKNGKFERFSPKTTPEELEENIKKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXK0</accession>
    <name>A0AAD5TXK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001854">
        <property type="protein sequence ID" value="KAJ3200686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXK0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="302" mass="35035" checksum="B762C4DF9C166D28" modified="2024-05-29" version="1" fragment="single">IYEDMVLNLVSTLSNQLSVEANLVHNNQTTFSIPQNTTSPDLPIYHKTSLIKQFLVIIVRVTKNIILENISVDCNWQVTTMEPKENTQLFKLPLDCTGQSFALKFKQITDSSDEMNFSTIAIKKKKKKKFFSFPDFIFNLLNLVKLIKIEVDELSKNFIFEKIKNLNLKNFCCFGLICGNEKLRFNVEVFETHHKEDNNNMKNFTPPHSVADLCKGGELEAIFFDNEEEEIIEKLNKKKKMNMDMLERESPTSPFSTSSSNDLMDINNSCSFNVEFNLVFRFGSDLQFVFNNINNFNDYQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXZ9</accession>
    <name>A0AAD5TXZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006776</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000604">
        <property type="protein sequence ID" value="KAJ3214632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="381" mass="44002" checksum="612DD3F1457D231C" modified="2024-05-29" version="1">MHVPDVDKGKENVMEQKKKKIILVKPSCSKCVELNIVCVYLAPKKRGPNPKIGDEWTPITTSPPSLDVMNNLNLNATDSNFLLFSSQPDFSLHQPNLVNLMDINQIEDILLDNSDFVDVKTPPGQQEKNFSFSLFDNKNMDDLNYLKNDSFLDNSNSEFFKFNHGCDPPTFFGLKHFENSILDVTNNFQELSITDKKLDGYQYLANFHFEDSVSYENHPRYVNSTKSQQMQYTLFDAFFHSKTVNLFFCPPQTDKSVFILWLSALTDPKLIMDAFDYGSQISSKFWINAYNASSSVYLRHSAFEISQKFSAIALTEMKNLSEKDKLEEEAFEGYFELASYFLFINDSRTTRRLLLETFKCLNEKDFILIQPLHYSALWATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYK7</accession>
    <name>A0AAD5TYK7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Origin recognition complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ORC2</name>
        <name evidence="9" type="ORF">HK099_005587</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the origin recognition complex (ORC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ORC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000441">
        <property type="protein sequence ID" value="KAJ3217145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYK7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056773">
        <property type="entry name" value="WHD_ORC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24882">
        <property type="entry name" value="WHD_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 2 RecA-like" evidence="7">
        <location>
            <begin position="103"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 2 winged-helix" evidence="8">
        <location>
            <begin position="302"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3217145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="374" mass="43306" checksum="2F9A43AF9059DA64" modified="2024-05-29" version="1">MVLDSSDDSEEREFCVNNEPEDENIEEEKSVASNYSSDSEMEQNLLLDFATSHKRVADSDNESISSDILNRKKFKKKRLGLEPKNKVYFLELANERLSKTSDNTCAKLPSMTHQNLLEYLEYYEQKHLKLILQNEKYYEKDFKQWFFQLNHDGLCLVNEKSQNTLSQLSTIKNISLICSVDHQNSTLLWCQKLINLFRFSMIDLTTFKNYSVETSFENSLMAKLTSDQAGGSSGFNGLTLSGCQYVLKSLPKNSRKIFKEFLSHQINEMESKNNERFSQDNEVLESNTKTTNKTKNASYKNCGMNFETLYLICIEKFYASSRQVLQTILVEFKDHNLIVYSNSESNSNDNMGDDQNMVCPMDLENLKILYESID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYW9</accession>
    <name>A0AAD5TYW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000481">
        <property type="protein sequence ID" value="KAJ3216374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYW9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1470.10">
        <property type="entry name" value="Photosystem I PsaD, reaction center subunit II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053233">
        <property type="entry name" value="ABRA-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21715">
        <property type="entry name" value="RH04127P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21715:SF0">
        <property type="entry name" value="RH04127P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="742"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="325"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="427"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="747"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1013" mass="117967" checksum="155BFFECA796DE1C" modified="2024-05-29" version="1">MSTQQTVLEEEFDENYEPTEEEILEYAKFIGIDPIEEEELLWIARESLKAPLPENWKPCQTEDGNIYYFNFITGESIWDHPCDEHYKKLYETEKEKLFKKKKSEGNNNNPASLTPIGVKSLPTNLMELKTLLPKTESERKPVDLKNDFNDSKSTSSSSSSSSSSISINKDRRTKYLSSSKLASIPSLPASQRNSLDPNVNLSPIPKDINLNASTIEKGELNKLSSVKKLASEEQAALKALETKLKEAQLKSKNDLHSLELSHEKEVADLRLKYKKDVEDINKSGKKEISDLERNFETEKIKLKTKQSSEISKLLEDQKVKITEIVKQHQNRIKEETDKNEKLLNETKLKYKTQLEEVKVKAEKELEETKEILEKQNEKSLDEQKKKFKSEFDLIKKEQYNERLSVVGEHRKEMEQLKRDGGESVEEKKKIDEDFRLFEQEKKNLEKSKQDLEKSFATHAEEKSLFEKSKSELKKYTNLLDEEKKMLQKQELDMKRLKEQQEAEQDQLLKKESLLEEKKLKLKEENEKFELNLKNLQEKNLQLGEENKKIEIKSKNLYEQTENLNINDKSRIEILEEKAQLEELENLNRLISEKKLALEKERRELEIEAENLSKLKETLQQEKNIIKDLKVEQEQKKYNLETSGIDDSDTKLKIDTLKRLKELETLQDTFRLKLKEFSLPIKEEPNKSFSEFKVDSDEESASDYVRKNNKKNISNKKKEKVFEELSVSDNDSSVVDNKYITKTRDIGNSDSESSHAPASPTTLLKRKIKKEENQLKLAKESLKEEKVSLKTKKEELKSTRIKFKSDIDEITKNLDKTIEVPFFNNSKEFFKSENENKQRGSGYFESHKSLPTFSSIEREWVEKENERNSSNRNLNISSNYAESVDSIPQHHKGHAQNALSEIEGELSKLLGTLKNSRSYISKSPTRPTSYMDAQINSTEKLYNKNSFHDSQILRKKREMNNLGGLGNVGVRSKEGKDMRKRAWEMSQVRSKATIEDHNAWLQDFKLKSLALLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ13</accession>
    <name>A0AAD5TZ13_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_005516</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000432">
        <property type="protein sequence ID" value="KAJ3217340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ13"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="83"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="153"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3217340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="204" mass="21878" checksum="ACFCE5380257FE3C" modified="2024-05-29" version="1">MANKASKVLQLLNYKLRVTIQDGRQLVGTMLAFDKHMNFVLGDCEEFRKIKPKGKDQLQREEKRTLGLVVLRGEIVVSMQIAGPPPKVNKEHRQSQSLPGPGLGRPAGRGLPIAPVGVVSQGLGGPVRGVGGPGQLAMQPQMGRGLPYARPMPPPGFRPPPPGFRPAPPGMMPPGFRPPPPPGMQFPPGMAPPQFPPGFRPPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ48</accession>
    <name>A0AAD5TZ48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MAN1A1</name>
        <name evidence="11" type="ORF">HK099_007165</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000671">
        <property type="protein sequence ID" value="KAJ3213850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ48"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF6">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="687"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="289"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3213850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="719" mass="83391" checksum="458EF60209EED3BF" modified="2024-05-29" version="1">MHAFGYDYLEPETKTGKNMYKDTLAATIIDSLDTLYLMNLKKEFNFALTFVKSLNNSFFERELTVSFFETVIRIVGGLIGAYELSNEKILIDTAVNLADRLLPAFVTLTNLPENSINLLTGMKATFPFSKGNLAEVGSNILEFTRLSQITGDKKYEIASRKALTYLETVIGPLSKVKGLYPVDIFVHDDKPILNYERYSLGGCSDSFYEYLLKMSVLTKGKDMQSKKMFTEAISQIKAYLINKNEEGLMYVSVFQPRNNYDDDGISISFYNNKKLIKGYRETKMEHLSCFVGGFFALSVMSGNSENITEDTTIAAGITETCYQMYKRQPTGLSPESVDMNSIKLDSQDGESYLQRPEALESIYYMWKLTKNKKYRNWAWEIALSIEEYTKCESGGYSGLKATFKVLEKEFKNNLQDSFFLAETLKYLYLIFDDDNIISLENFVFNTELFTGDYKDMLKEKNVIMMCNHQEFVFLKRKWDLDKIGYANTLRRAIDDNFPLWFLIFPEGTVVCEETVLTSQAYAKKMDWKYNPKHVLNPKSTGLYHACEILNKSVDYMYDLTMAFSDISSETYPYDFFSLPKCFFKGEGPNQIFIHCKKHKIDLIPGFKEKKPALDFLNEGEEKKLTTEELELFQNKKRGELFGEWVRDQFKTKDEMLKKFYLTKELKLLNESEKSTLICKMEPRVKDYVTVTTAFVLAISLSYSFFKFLYYLIKFFFFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZD2</accession>
    <name>A0AAD5TZD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Erg26, C-3 sterol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ERG26</name>
        <name evidence="4" type="ORF">HK099_006163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-beta-HSD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000515">
        <property type="protein sequence ID" value="KAJ3215862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZD2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF51">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="3">
        <location>
            <begin position="7"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="338" mass="37736" checksum="EC608CAF8E02486C" modified="2024-05-29" version="1">METKKVVVIGGSGLVGQYIIKQLLNDKSVNYQVTSFDLTANSLSHSVIGDITNIAQLTEALENVEICIHCASPRTGLGKEIYFKVNVEGTRNVVDACKSVGVKKLIFTSSASVVYNGQHLLNANEDLPHCDIHLDAYNETKSIAEKLVLEANDPASGFLTIALRPAGIFGPGDLQASYSVYKAAKEGKYKYMVGENKTLFDMTFVGNVAHAHVLCCKNLNAENSGQAYNITNDEPIYWFDFAKFFYDGLGRKDSLKIQIPFTIAFPMAAISEFFGHLFKFEVLFTTFRMTFLSTNRVYDISKARKYLGYKPVYSLEEGLESTLVWLTELRDKDTEWKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZE9</accession>
    <name>A0AAD5TZE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006121</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000509">
        <property type="protein sequence ID" value="KAJ3215948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZE9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050838">
        <property type="entry name" value="Ketopantoate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765:SF2">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43765">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="8"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="163"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="399" mass="45016" checksum="CD75C5E641D48316" modified="2024-05-29" version="1">MPENKPTVVIYGTGLIGMFLASHLINTREVNVYLIGRQSTFNRIEDTVETTSINGFKTRVNKTELNFFSTFQSLPSEIQKPDYLILTMKRQDTEAAIKDIDFSHGKTTIVALQWPFNVVESSPGKYQQSSSGSIYLTESEKGIQLKDIFVSSNLECNVSKDMDGILYGKLLINLNNAVCALSGLPILKELQSTQYRRIWANCIWEGLKCYAAAGIYPISFTFIPLWIFPWILWFPFPMFVFQKIGETVFKVNNTTTSSLYEDLKNKKPTCEIEYLQGEIVRLGEEMKVPTPVCLRVKNLVDKAIEKKEGLVVNNPEVILDWIEMINLFDNPSVKTLENPSVHSIHCLVEVPQCVSSLYSILAESKNATSKYVVSFKFGEDATNLLKNSAISHGTDGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZF8</accession>
    <name>A0AAD5TZF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000659">
        <property type="protein sequence ID" value="KAJ3213992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZF8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="607" mass="69870" checksum="7182AEA94712E9C9" modified="2024-05-29" version="1">MSDLWKDRLRSRETLVTNKSEKIKNVSEQSKTSKRKRQTHKKVTSIAKKKLKTVNTKKPTRFDKNNFREKEISTEDEFWSSPPAKLRVASFKTAIAQDKLKKIDDDGCWLMTPFSKKKSNTFSIRFSTPNLESPFKRFNVSQENLQQLPNLMTNLSDDSDDDTDQNLLFSDDEFENKTPSYEDQNSNFLALNITDGLFPAKVILLIFKYLLNSSSKFDLNFLILCKSWSLLGRAALWENLQFQTVGKMKGVFNIVCKKDATRNLILNQGLSKYGRAFLYSNFSSENEKKCIKVTNASENEKRIRTETLKAVEYSNLVKSFSYSFTQPKDNKTNFPVQCFFANDLFPNLTKIVFFGSPAWLNDSLFKVISRNNSITKNLQNFQLSNPGLTKFKFISKFKNLKILILENSLINDSELDFLGKNLKSLVKLCLPLSKHISSNGIDQFLLHYPEKNCPIQFLDLNSCSNLIDNSIFEILFQKNLLKLQNLHALNLGNILGLDYTTGLKNILLNNSNNLEKDGFKLKMLNLSNLKDFDDKGFLLLLKSLGSNLDILVLRNANHLKKSEVEKNLNNFSKKLKFIDLSGCDFNFIPKVKNNTNLKFIFDFEILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZP0</accession>
    <name>A0AAD5TZP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication complex GINS protein SLD5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004905</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The GINS complex plays an essential role in the initiation of DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GINS4/SLD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000361">
        <property type="protein sequence ID" value="KAJ3218881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZP0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11711">
        <property type="entry name" value="GINS_A_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008591">
        <property type="entry name" value="GINS_Sld5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038749">
        <property type="entry name" value="Sld5_GINS_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206">
        <property type="entry name" value="SLD5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007764">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="5">
        <location>
            <begin position="94"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR007764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="211" mass="24849" checksum="EA7106AA77739B0E" modified="2024-05-29" version="1">MFGEELENTHLSSICNTADVDGSNGFNTQDFLNDDSEGASEQSDIDLFTKAWINEKNSPEILNFKKELLESLSLKLTTQKHFIEEENLEIFLSSIYLQEIERLKFLIRSYLKMRLEKIEKFSLDFLVNQENRLKLSSKELSYCEKYQRLKQEYFNKTCLEKLPEMLRSIEEKNEMGLSMIVEPDLNDSVLFKVDKSIEIYRLEDRLVTIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZV2</accession>
    <name>A0AAD5TZV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_004747</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000345">
        <property type="protein sequence ID" value="KAJ3219249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZV2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M14" evidence="8">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3219249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="199" mass="22655" checksum="E7737FF5FB95036F" modified="2024-05-29" version="1" fragment="single">TRIFFIPVLNPDGLIQVENFLKVNSVVEVEKKLKTFKSFKKNLSPTCKPKYDITSFENGVDLSHNFGFKWGNLEKNSLQEASYKNKCSENFQGASAFSEPETEALKKFILEENPKISVFFQTNLKDEIPNNNDDLNFSTNILFPFTFHNSPQKVIRPDDLQGFQKIVADMNANSVKNQFESGFAIDIIKSTIVGSPIDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U026</accession>
    <name>A0AAD5U026_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent RNA helicase eIF4A</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Eukaryotic initiation factor 4A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">TIF1_2</name>
        <name evidence="21" type="ORF">HK099_008524</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000945">
        <property type="protein sequence ID" value="KAJ3209343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U026"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18046">
        <property type="entry name" value="DEADc_EIF4AII_EIF4AI_DDX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044728">
        <property type="entry name" value="EIF4A_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 15" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 21" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Chitin-binding type-1" evidence="17">
        <location>
            <begin position="47"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="20">
        <location>
            <begin position="678"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="709"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="891"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="16">
        <location>
            <begin position="678"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="1040"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3209343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1040" mass="117193" checksum="4AF21083C757822F" modified="2024-05-29" version="1" fragment="single">LFYDEKLDDRITLRLKKNIIPGQILTTETEPNVEFVFHGHKRDENSNIPCGNGVVGNGLCPQDLYYCCSKEGYCGLANNNPNDPYCGPGCKGGPCNKGPDDLFVDHSDKEESSAEEDDHKMFGSQKGVTECSKPFNGCVYGNWNDKSCQCDCIGANNPKSNGYCLSANGQCLEAKKYKYPDFYCEEILNTATTTASDAPPVLIKYYGGPVIKNVEVTMINYGSVDYAFELKYFYKEITRSAYWKILTEEYSTPMYPIGNGTYKAQINVTQTKNKLDDDADIKPMLLNLIQAGKIYPNENSYYAIHFSPGTVITKGSSASCVQFCAYHGTLKLSATLEAKLGTKYVYYGIMPDQGTGGCNGGCGSLKNTRFQNLCVVSSHEIIEAVTDGGVGEATSYKSPLAWYHSPMGEVGDLCNSQGISFKTAFGNQIYYAQRLWSNKYQRCVADATGAINAVCVTQVSFFWNQVEKMKLISCLKRHNKTSPYKHAFATTREDAELLAKQKQSSCADKKNHTSLQLVTLNHNRNNLKHNRKKVRFDENSPIKYSPTFGHLNDAYGYDLQFFPHQQNLSEKQLKKFEQKLKLRREKESAELKNSKDEMNGLNRYISNQDTSCSLSVQLPELTKENSEDNLVDRFDGLSIKTENLAPVLWKEVVAGVLGGDEEEFDSVIEKSNWDQVVEKFDDLKLHQDLLRGIYAYGFERPSVIQARAIAPILAGHDVIAQAQSGTGKTATFSISILQSISIELREIQALVLAPTRELAQQIQKVIIALGDFLNVDCHASIGGVNTREDARKLESGPHIVVGTPGRVFDMIYNRRAFRTNELKMFVLDEADEMLSRGFKDQIYEIFRLLPTTTQVVLLSATMPVDVLEVTKKFMRNPIRILVKKDELTLEGIKQFFVGVEKEEWKFETLCDLYETVTIAQAVIFCNTRRKVDWLTEKLLSKDFTVSAMHGEMTQEEREQIMREFRSGSSRILISTDLLARGIDVQQVSIVINYDLPLNKENYIHRIGRGGRFGRKGVSINFITAEDQRMMREIEEFYNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0B9</accession>
    <name>A0AAD5U0B9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004406</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000309">
        <property type="protein sequence ID" value="KAJ3220305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0B9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="346" mass="38280" checksum="3F9EF9B8A6CFC696" modified="2024-05-29" version="1" fragment="single">MHSILSININYQTEPMTEYLSTPIQSYAGQDVCMGYFPTDDLISQCVLSPTPNSPLSTISSLSDISTSPFDDFDLSDGNLGIQLDIDINSSQYFRSNSNSLHVDSFNSPSTTQQSLINSPSFNFISNIPETTIPNVNPKQILQPAITTKKSSKSKFESPKLVSQPIILNSPLPETTVFNDLSQDFTVPNFQNQVPSISSQEQVVASPTIISNTPYQFQQLLSPVESSPSSTYPNNNNNSLVDDTKSFMEILPTNFSAPSVSSSTSSKDDLVKEYPCPHCPRVFPKTYNLKSHLQCHSGVKPHKCSAPGCESSFTRKHDLQRHVRNIHKKPNSKKKLKLLNGKSKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0H4</accession>
    <name>A0AAD5U0H4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosome production factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPF1</name>
        <name evidence="3" type="ORF">HK099_007053</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000652">
        <property type="protein sequence ID" value="KAJ3214075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0H4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000002">
        <property type="entry name" value="Ribosome production factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF3">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="97"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="293" mass="34629" checksum="797CA6658940810A" modified="2024-05-29" version="1">MARLMQASKIPNKIKREDVYNKIRSQKNKDKLLKRKQQKKEEELDPSLKEERLKNNLPNTLENTREFDETIVEDDEEVLKEEEIDDFSQYFNDSLQPKILVTTSRRPSARVYEFAEEFCSIFPDANFVKRGSQFEIKKIVDIAIKREFTDVVVINEDKKKPNAITIIHLPDGPTAYYKLTSIMSAKEIHGHGRMTPHKPELILNNFNTRLGHTIGRMFASLFPQVPEFKGRQVATFHNQRDFIFFRRHRYIFDKEGKKCDLQELGPRFTLKLQSLQKGTFDTKYGEYEWVYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0I8</accession>
    <name>A0AAD5U0I8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000525">
        <property type="protein sequence ID" value="KAJ3215719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0I8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="16238" checksum="5B6604809F9A56B8" modified="2024-05-29" version="1">MIFAFSCLSHNDLPKTNKQKVHSNTVNLYTNIQQNSSATTTIPQAITENKSSTVTVKPTRSILKKKRVQPMENKKEMVRSLSGSSITFSEVTLEYPTYSNSEYNRIGPKKKSYELADSEELQDEEAEYVEKLKKIKENKNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0M9</accession>
    <name>A0AAD5U0M9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="8">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_006158</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000514">
        <property type="protein sequence ID" value="KAJ3215882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0M9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF6">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="345"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="512" mass="59015" checksum="20300BB529A9C4E7" modified="2024-05-29" version="1">MSKFNTKKTCQYLLCFFVFVYISSLFILNSYFSGSNNDLEFSVSSQNLKKAHQINLIFIVQNIKNPLNNNFFSGYKNLKDSSKTQSYETESIRNMTRHAWKSYRKFAWGSDILRPVTKTGGSLAFGIQGIIPFTIIDAIDTLYVMGLNEEYLQAKNYISKLDESTFDVDISVNFFENVIRLLGGLISIYDLYGNINLKSGMHHSGWKPNLAEIGSNSLEFTRLSKISNDPKYAIAIKKSYNTIQNVLGKDLPIPGLFPQFLNVENAKFDRDMVYSLGANADSFYEYLLKFYLLSKKTDMQTSEMFDEASKSIKKFLIKTSKKNGLMYIPDGEVDNLNTVMQHLTCFAGGMFALSVLSGKSENPKEDTEVAAAITETCFQMYERQEAYKLSPDFVDMESEKLRGNREHNAYEQRPETVESLFYMWKLTADKQYREKAWKIAQSIEKYSKVKFGYTGIKDIYLPLESGNFNNQQDSYFLAETLKYLFLIFNDDDKILNLNEWVFNTECHPFKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0U1</accession>
    <name>A0AAD5U0U1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005664</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000451">
        <property type="protein sequence ID" value="KAJ3216950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0U1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="93"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3216950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="145" mass="16382" checksum="4624382358DFEA55" modified="2024-05-29" version="1" fragment="single">MSLLSLNKNQNFQNSNHRSSYPHSQDSTNKNNQSHSQEVNSVHTLVDKVDNIVGSPIDATETIPTSPQISRLRKIASRSSIRITDLEVGPKNYEKVKLIGKGDVGKVYLVKRKENGKLFAMKVLSKNEMIKRNKIKRVLAEQEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U106</accession>
    <name>A0AAD5U106_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">tRNA (Cytosine(34)-C(5))-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NSUN2</name>
        <name evidence="13" type="ORF">HK099_003949</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000268">
        <property type="protein sequence ID" value="KAJ3220858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U106"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016428">
        <property type="term" value="F:tRNA (cytidine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057285">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057286">
        <property type="entry name" value="PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023270">
        <property type="entry name" value="RCMT_NCL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25376">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25378">
        <property type="entry name" value="PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02011">
        <property type="entry name" value="RCMTNCL1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="12">
        <location>
            <begin position="4"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="388"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="116"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3220858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="660" mass="74022" checksum="91D070961E012BE5" modified="2024-05-29" version="1">MARVGKDSSKENRKSARYEETQLNNENFTKYYKSLGTVLENEWDLFIKSLQTPLPVNYRFTAFELKELMIKEYFPDLKKVTIDGISVPIPAPIPCVSMIPPLLLDVKPYHFVMDMCAAPGSKTAQLIEAMHSEKGDDIPDGLLIANDADYDRSYMLVRQTRRLQSPCLMVTNHEAQHFPHILYSGTDPGEKKKGLIFDRILCDAPCSGDGTLRKNKGIWKSWSGNNGNSLHKVQLQILEKGIELLKIGGRIVYSTCSFNPVENEAVVAEILKICGKSVELLDVSKELPELRRTEGLSHWTVMSKDGTIYKNYEDVPKEFRNIILPSAFPPPNSTALGLNKCLRILPHYHDTGGFFVAVFKKVGSFGFLDRFDITDDVSVLNTNVKELPHSEKHHLSDEESRDLKRPKIAGGTADESNLDVVSNDDGNAVREKKGGKRKWRGKESPFIFLAPQSDEVQSVVKFYGIIPNALPIDQFLVRSDSEKKKTIYFCSKSVKNTLQAKNVAKLNIVNSGIKMFTRNEGDGTIGCDFRLCNDGVSIIANVTTKRRIVAKLSDVLILLREPYPKVDKFSSLIIDGLKELGPGSCLFSFNPSTEKSISIKLPMLLPIWRAKASCSLLLDKAECRSLLLRLTGEEYLPKKLEIDKNDNQEVLENSAQQEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U144</accession>
    <name>A0AAD5U144_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Epoxide hydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005779</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000466">
        <property type="protein sequence ID" value="KAJ3216671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U144"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016292">
        <property type="entry name" value="Epoxide_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001112">
        <property type="entry name" value="Epoxide_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="377" mass="43434" checksum="CFB135821F3DE6E2" modified="2024-05-29" version="1">MIEKFSVSFHKGDIDKLKLKLDLTEFPDELTNTKTHYRLNYHKGLIEKWKKFNFKNFESKLNDFDNFYFHFNNNIKVHFILKKSSTKDSKVLLLIHGWPGSYLEYGKVINPLNELGYTVVVPSLIGFGFSSIPTERGYNIEKNAIILNSLMLELGFKEYYAQAGDWGSYVVRTLGHRYPENCTAVHINFLMPNNLNKIIRNNKSKKHLLSNLSDLDKIGLSKLDNFAKKGRAYFKIQAEKPERLSFALSDSPSGLIGWIGDTTMGASRFRVTEDDLIENATLYWLTRTIASSIRLYSEERYVQYPEPGFVKVPSGITIFPDEMAYIPLSWAKEYLNVVSYSYAKKGGHFPQLEYPEIYIAEIHNFFSKFGGKPASKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1H8</accession>
    <name>A0AAD5U1H8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endoplasmic reticulum junction formation protein lunapark</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in determining ER morphology.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the lunapark family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000244">
        <property type="protein sequence ID" value="KAJ3221208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1H8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098826">
        <property type="term" value="C:endoplasmic reticulum tubular network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071788">
        <property type="term" value="P:endoplasmic reticulum tubular network maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903373">
        <property type="term" value="P:positive regulation of endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040115">
        <property type="entry name" value="Lnp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019273">
        <property type="entry name" value="Lunapark_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166:SF12">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10058">
        <property type="entry name" value="Zn_ribbon_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Lunapark zinc ribbon" evidence="3">
        <location>
            <begin position="114"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="298" mass="33776" checksum="C6A6CE0D16BAC986" modified="2024-05-29" version="1">MLNKTKFNDLKKIVERYESPQAKKERLLSEQEILLQAQNPQVLKNEFQVNPFLNKPTQQMVPTPTQLRHMNNLAPNLPTKPGAVSVQPIPNQQFLDVTSSPHQLVPASPTPRGWMDKMMDTIIGDDQFNKYALICQSCFTHNGLCLPEEFQNTKFKCYKCNFLNIRGDGNFPVKSMTNSPSINSIVDTDTESHIQDSLQTSLLDSINDNDNQVLSEPQQKVDQVSTPNILIQNATVVEEITVTQISKEILVEINQLEQVDEGKENSTLESTNSSIPHHRHHQESDEDLVMVSNEVEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1P4</accession>
    <name>A0AAD5U1P4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">COG4</name>
        <name evidence="10" type="ORF">HK099_005398</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000418">
        <property type="protein sequence ID" value="KAJ3217603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1P4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048684">
        <property type="entry name" value="COG4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013167">
        <property type="entry name" value="COG4_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048680">
        <property type="entry name" value="COG4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20662">
        <property type="entry name" value="COG4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08318">
        <property type="entry name" value="COG4_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20663">
        <property type="entry name" value="COG4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00762">
        <property type="entry name" value="Cog4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="COG4 transport protein middle alpha-helical bundle" evidence="9">
        <location>
            <begin position="193"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3217603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="788" mass="91774" checksum="E48EFB3A51C7E51B" modified="2024-05-29" version="1">MGTTAVISLMLSSDQNVPPASTETTINNEQTSMNLLSVRLLTDIETVMEQLYLLNQEERLLDKELDKQLQIHPQQMMEKIEFSRPVISTLRKESLDLQKVITDTDQLAEKISKKVRLLDVEQSRVKDTLKLLEDVQLINMCSQGVIKTIQEKDYEEAANFIHIYLNNFDLKQLKLVFETKDETDIEPDPLQVLSQSQRSVKDMITVEFDNAVSNGKQEEIFRYIRLFPKIGEPLLGLDKLGSYFTGLISTQCRDNMKAQPKDGQTFFANLLTKLFESTANIVDQQQNFITKEFGSSTWILFLLQKLHRQAELQASIILDNFIEKASIQRKLYDIKQIKQQQSTILASSLGTNNPDSKSGELMDFRELDLVLDEIALISQRTVYFSRFIKSRAKREIDQLEKPKLEFQELLKDYDKDGVSNVNKLSQRVEELMNDYLIMEEFYIKKGVEKAIKLDKFEAGNLTSSCVDDVFFLLKRSTLRCLQSFNIETLGVFMTNLGRILDVDYLQIFKKKLQNFNNLESKENKFGCMILINDIDLSLDYIYKLSLEVQNFVLKGIVGVGEFEKERMKASLTLFEEFGKNFQQVIKTWIEILYNQSLKMKCRNLLTDSLNNIKYQINEDEFRQISAEELFLKKFKSSFLKLLKVYRVNFTKKNFKLIIKYLLENLCKELEKIIFSNFKFSSFGGLRFDKDVRGLMKFFGEGGEVFGEFEVEEEDYSKKGENYFESYKEIFLRLNQISQILNLEKVDEIFDIWGVGGVIVKWRLTSNEVKKVLALRPDFSLDEIKKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2B6</accession>
    <name>A0AAD5U2B6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Myeloid lymphoid or mixed-lineage leukemia 5 (Trithorax, )</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MLL5_1</name>
        <name evidence="7" type="ORF">HK099_003154</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000210">
        <property type="protein sequence ID" value="KAJ3221764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2B6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15550">
        <property type="entry name" value="PHD_MLL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462:SF3">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20826">
        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="324"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="600"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="904"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="989"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1047"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1116"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="600"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="906"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="924"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="942"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="998"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1047"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1116"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1154"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1177"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1207"/>
            <end position="1220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1220" mass="139264" checksum="E63E1228E00D3D64" modified="2024-05-29" version="1">MSVSDQIRCICGITDDDGYSIQCETCFVWQHVECVLDGEKEPELYYCEQCKPRNMDVTRAVGIQMDNRRKAKTDKPRRSYVRKDKEQRISPKKPKRKERDSRFSGKDDEDLNLTSPTFTKRSIKEDQDQNSRKSMKPFKKKADFGVESPGSLDDDNPTVLQYFNERNAVSFNDSSYNLENNKSPTLFSMELDAILDNIKDYNKNFSSENYLTRDGSSIKFDDLYQEQYQMYKNDRQFAFSNRFLNRDIENLITAVCKKLQNEILQISNSVGENENSSVLPWGGKVGWTFFEDSPEEKCEDNLNFHPIVIDQEAFESILGLVTVEEIEYSDTDQSGLFCTSNIVPKGLISEINGTLSFFSDVGGYIVNNEFLKEGNYTDKPKFLIPPYVFMHPAKIFSRNGSFLQNQVVVDSRKIGSADGRFVRSYCGGDPMVEYLCNAELRTVFIISQDEEGDTSRSKLNYLKPWDQLKLCIFSTKLIKATEEVVIDCSKGPYNVLYHSCVCKNEKLCIIKQARITPNCEAVTPFLSYELQPMTSDLKNVKHLEGQSNTCFNKLEKDVGAMKKIWLKKLQKESLLKNETQLTSPNNEAVPSSFNEAETKYRSESNKNDALDIKESNSNTKDSNTELKECIPQPKKIRLGEYLESRSHAEKFSDKSLSATAQSVTTCDATNLPDKKGNVDAKDEAEPALTNPPVNIKKVVSLKDFMLKKGLSLQTSSNNLISEPGTVLSEKPKSENLNLPVVNSPKELEPEDVGYFPVQPFSFAKNLEKKMAIDEPTQLVKVPEKLFAPLFNETSKNNDSITSPLKSTDESNNVFKTGKSVVADPVSLPKLNVTLLNDGNSSITNEDQKDAELLHQSPLNLVKTPNPSLSNFSRLSHSATDIQRHGSLDLPNRSSVAEIPRVLPMHQHQQQRSQNELSLEHTPQRQHSGHSVSEQRSAEHRSSTSSNPKKSSPITTAPSALSDVMDIPMSTDKNLLTQFLNNDASLTKKFEGTSGEATDNTKTRKYDVPKDERSFQRNTLRSRNSEKDWGGSSRIHSHDELNRLDDREPYFRGESGWDRRNNNRYDRIPGRGRPGEFSRGVNRFRGSNNRFRDRGDYDRDYDRDFDLRNERDYDNRNEREFESRNSGDYELSSEEGERLGSPYRIPVGRGASDWSNERVSDRNRPIFDNRHPHYPMRRYIDPRGEPRWPGRGAGPRNPDNQNRYSLPESRREWSVDRQMDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2D7</accession>
    <name>A0AAD5U2D7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000311">
        <property type="protein sequence ID" value="KAJ3220218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.230">
        <property type="entry name" value="Alpha-catenin/vinculin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="877"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1562"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1562"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1574"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1592"/>
            <end position="1602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1777" mass="196872" checksum="70A854AD77131A38" modified="2024-05-29" version="1">MLNGTSKNRNKDERLNLIIIPTPTTTVESADYGNSPNSSKRGSTSSQNSTSINKMQLRNIKNSVNLISTKPSDAKSKKSSASPQIRSPVYFREIKEVNMSHASSPTYSDYLKRRNGSISSQSSTQIKNFFGRKHSISSGNSKLSSTVIPYSHKTLRQHCLACMMQKDGLNKKSYLNQTTSSINKTRKKWVPPGMVPLGPPLVDSSTYDSPVRLNFSSKWRPFSRPLPEKVGYLTTKTDLFDKRKILNKKKSIIGEEPKKIIQDIYEEIHEEIVEYCTHHDHYHSSPDNFTLFNDLNSEFGSESTFQEDDRDSVSSSTNFVLRNHTFENFVSIKSATNKALDFEESNSFHNEFQLSTKPDFVESEFYNNFDVHTKADTLSSSNVGSIEEFQVPAINAICDSQNEFITVLNEVDNIEINGEVNKILLEVDIDLENKNVTEEVVFDFAVNEKESVFENVKIKCFEEQFDNNQSVQNFDGVSFTSPTEDESGYSQIQIAADISNLPTHSQCEVVISENLKAVEINHNIPLKKSIEVLNPPENHVAVDIFDNLLDNFFLLGDSKPSNDLNVEVQSLANEDSINEAFKINSKEDNLEMSSSVNSALASIKCEKIVDELHQVEENGSSINSLDFVYLPILENGTSTCSLSEKINNELLIEKSNSFNSTVAKSQIDELEDSFFSNVPIEKLLMETKTITHDLNNNATADEAINLTQVTKYLDSAGNNPMHDDLLDTPHSVAYNFMDDTALSYSRIYMAESEDASTPESCLVSRSEPEKELRVSSPGCNKVRIADCTLFVASVEEKDKITELEISDANEGSLQSRNIEVTSYTPDLNKSLCLVQKELVLTDDTNQSISSYELLQQASVSSRSGVFDTPFVEINDEEIDSKEKKPSNILEESSLDDSPHSNAVNSDQKNIEVSLLINVETETSIESPSLFRSFVSKFVNSVDNSAIEDDDVTKSAEVDEKDEFPALTPFEPVLAGQNSLVDKSKVAECIRAEEVTVNSVAKGSSDVHKDFLKVKVEKRTSHDDITFLQECKDEENFHSDDPDTVKHTEETSHFNAILSAGGLVGSAIASSLTATAASKVTMGVVGGVASGLASAGAVSALATIGTASVGLASIGLGIAYLHSGEEQASSQLSKEQCISVGAAEDVDIRGKEKQTELTPKQKFSELHDNTISQSYPHYQNGENDEKTNFSVLHHSVSKKFETDLISHNYENGMKFERVASDKSDNAIKVETGTLYQKEGKRTKIETDTVGKIYSESENIECKEDFPTSVLTTATSVNCFPQLLAEDVISATIVVPAATEINVKKRGQQKVLTSGSVISQLIFLNLYLKQGSDKMQLSNGSLLLDVSAGSLPQRLCDTVYESQINSSMVMKKNVVGELPIVTDSNLDLETNSSDAANVNSLQAVHNTMENSILIEPNAAVTTLYNADTIEDNNHLAINEKLHDYFREEICDQTQQSKTFENVLSDTDSQEKKLYESNIHPSLGNEVNYDFQIERKKEGTNNKDTYNPELQIIHDFLLPVVQLAAKPLIFRQDSWNSTEGSIEYDGDGNIINAYENTKRISRTASEVSSVKSSESSINTKQKSSLLNNRHHKKSTSSLSDFSNTSAGSGANQEWNSWRKSIKKRKPSFDVTDLTSLTVAIPSKVLKLEANFKLLQKLQRLLPEMVKGNRPVPPTPFRAAKQSYIQTAQGLYRLGEEICKNWLPICKTCSDVTLKNHLLTSLLKVETLSAQMKAVVSISASDTFDFDESGTVLSCSKNLMETCQKACEDLHAAKLRINGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2F6</accession>
    <name>A0AAD5U2F6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000181">
        <property type="protein sequence ID" value="KAJ3222307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2F6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="54"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="498" mass="57836" checksum="1DAAD137042081A9" modified="2024-05-29" version="1">MHFIDKLLKQRKYSNKNNIKSTSSCQGTKFLNFSKEDTILHISSLKLHVSKKYNHTFFKDPPLKQYTNSSDIFSKFQLYAVFDGHCGQVASKFLKHRFAHHLVQTIAFIEKDYERALKDTYEQLHQILINCEIYKPESVDYASGATASVVLITNDTTYFSFLGDSPILIWRRSESEPTMLFEEHDHKNNLIKINLVDSNMFLVLIKEQMNSLVYFLLSDKEAKEKVLNGKNNVLNVEEDNLKYDDMRVGLAALNVYGSLGDSSYDPEPFNIFIDEVVEYRKAVQNNQLKKGENKNIKNIETLETNSNTFQQQSNETLLQQDQNPDDLNYDYNEFVEFVAGRPNYDVLQKHMALKKKAQPSRVLQASIKHLNIDNKIITPGLLRVPETTSIPNAELRQILIASDGVVRFYNYLGSEIRSVLMSNYKNQDRIVDELKDYLTWLRDDKSIIVVEFNNPEIEVHDVKGKIRNDGLFYLDDSRRVYQKKRKAELHQNRSNLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2G0</accession>
    <name>A0AAD5U2G0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphofructokinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_002710</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000192">
        <property type="protein sequence ID" value="KAJ3222095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2G0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.450:FF:000002">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050929">
        <property type="entry name" value="PFKA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012004">
        <property type="entry name" value="PyroP-dep_PFK_TP0108"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005301">
        <property type="entry name" value="PRK06830.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45770">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000534">
        <property type="entry name" value="PPi_PFK_TP0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="11">
        <location>
            <begin position="87"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="43827" checksum="F7AF00482C048DA0" modified="2024-05-29" version="1">MVNLNNSVHLKATDKVNPLQKEWEIKTLGSCEFSSSITANSFVQEERILLHTTFNTATNQLIDTPLESLEKAGPRAKLYFDGENTTIGIVTCGGICPAVNNVIRSLVNTASYKYNVKKIVGFKYGYEGLNPETSEWTILTPADVKDIHTFGGSLLGTSRGPQDVKVMVDYLQKMEINILFTIGGDGTQKGSLEISKEAERRGYKLSVVGVPKTIDNDISYVEKCFGFETAVALSQQPLRAAHEEARSAKFGIGIVKLMGRLSGFIALSAALASGDVNLLLLPEMKFTMDDVTNYLIQRFKKRSHCLILVSEGAGQDLCTIEEENGPKTDKSGNVVLKDIGLFLKDEIKNRLKKFGISPTIKYIDPSYTIRSSAPIANDAVFALQLGQMAVHAAMAVTYDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2J2</accession>
    <name>A0AAD5U2J2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000270">
        <property type="protein sequence ID" value="KAJ3220835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2J2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="383" mass="44287" checksum="A66430AD25EBD29C" modified="2024-05-29" version="1">MEISEDFSKFSINQSQRLPSLRSLQIEKLPTQAQTNTCDSSTSEKTTSSDDTIKDLPEKSVVEEQFCKLLDDLGLKDDVKIKIISNYNLERKWELIKMNNNTKAVDTPFDVKKFITFISNASISDLSGFELAKLRKKLTYQATSALISKLVEEGLLDEMEKITKKLFQGTFIGSRKKWEIQLEILKLLDIILRSQEQAGNILKKKILVYTKKLILDYHLDKETQLILNQREYPKSIFETSSFCAPLENRILFFKILTNLLKIVDDVVSVFDGSENEVTVSSADQNVTKEEYLNLFDAVFDDSMYNGENLLDLFEKENKFIFQSLFLELKYCVFERHKNLSGGDSKSNYIFNSLADGTYRWEKIIQARTKKYKTAEANEYIVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2S7</accession>
    <name>A0AAD5U2S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000168">
        <property type="protein sequence ID" value="KAJ3222598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2S7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042221130" evidence="2">
        <location>
            <begin position="23"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="427" mass="45830" checksum="B94CC2A54F75A967" modified="2024-05-29" version="1">MLLKLNIAIILTSYSLLSSVSTLPPGAPPAGYGGDVSLVSTTTAAIKIESTSTVTELEETTTVELPTTSNIETTTTESTAPAETSNSSQELTAEAAEATSLAEPTKTEEQPTDNSSTSEPTISTIEDVKTTELPAASDEEETTDLPSNQNTELPENNQESNAPVSTPNENSSENIGNAPVIDPKYGTNEQPELGNENGNVEIIQPKYNGGEKNEGANESVVIQPKYVPTYNGATENAKTSSGRKMYKCRSKNGKPPKTIKVTGGDNNIYSQSPNQNIDVSQQPTQNNNEIESDETPNQGLELPTEVELPPVAKEVSDILKNVNGKINFPDFIKTCKEVLPSEFDFEKFVELMMEFKPELTFQEFADAIGEAGIANLDDFDANNILKNFGGELDRSVILNVMGSLGSSLKSLNLDPSKAAKLLSQIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2T6</accession>
    <name>A0AAD5U2T6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">COPII subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SEC24_2</name>
        <name evidence="10" type="ORF">HK099_002089</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000167">
        <property type="protein sequence ID" value="KAJ3222619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2T6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01479">
        <property type="entry name" value="Sec24-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041742">
        <property type="entry name" value="Sec24-like_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="7">
        <location>
            <begin position="410"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="8">
        <location>
            <begin position="484"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="9">
        <location>
            <begin position="800"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="973" mass="108851" checksum="EAC5CCDAEE80E45C" modified="2024-05-29" version="1">MQSNYSFQNQPSNYNANLNVNQLQSQNRTTSKNPHDNLLVSDANDGSPNGQLISAENHLTATGASFNPTTSSSNQFQNNQQFIRSYNPNINNQQVGYSASKYGTNSQEGALQISNFAPANSLDNCNTSRLISPNSQQFQNLQGNDGKINASSHRNITAHVIVPPVSRVSNHDAVQHQQLPVDARFDNPPSHQLNNFGTKGYGYSDSLQYQNLPGQHSIQNTSHLLHNQSNENYYNNQVHNYSTTPNHINNLNQNNVHNTLVPQFSNNQHFSSNTQQFNQEYNNAYDRLNIVNVNQISNQLQNLAVKPAPLFKSYSFLSNNPPPMDNIYKSSEVLMDIEVEYNNKLKSLASAAKSPFSNAAECFMSCTVNAMPYSLKLLEKTKIPLGLVISPFNKEFEEKHPIPVINPEEIVRCHKCRTYINPWITFVDQGRSWRCNLCFASNELPSFFDWDSSTNQPANRLERPELTHGVIEFIAPQEYMIRPPQPVVLLFIIDVSLQSIKNGMLKAASKIIFDSLSSIPNVDGRTKVGFITVDSSIHFYNLSADLNEPQMLVISDIDDDDPYLPLPMDLLGSLDESRSLIENLLDKFMQGNMFSNTPANKNCLGKALKFGYKLLNSLGGKMVVLQSTLPNINEGSLKTREDSKLYGTAKEAQLLLPATQFYKSLALDCSRSQICIDLFIFNGEYNDIATLSSCAKHTGGVVFYYPYFTFENSLDVIKFSSEFKSFLSDSIGLEAVLRVRGSRGIQMTAYHGSFFLRSADLIQLPNVNTTNAFTVEMTLDENLTGGMACFQTALLHTSSSGVERSLSATLEDAREALIFRLIDIMSGYKRNCTSQGQTMQLLLPESLNSLPLFTLGILKSVFLREAKNINSDFRSYMLLHNYVSSIETNVVNIVPKFWCLSNIAVSQIGEVSENGEVKFPELLNLSADRLDKQGFNLLENGFNIFLWIGSGINHEMCQLLLNSDYSNLKNGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3F9</accession>
    <name>A0AAD5U3F9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Mediator complex subunit 12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SRB8</name>
        <name evidence="9" type="ORF">HK099_001495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000142">
        <property type="protein sequence ID" value="KAJ3223148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019035">
        <property type="entry name" value="Mediator_Med12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09497">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01281">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med12" evidence="8">
        <location>
            <begin position="115"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1464" mass="170572" checksum="B85819BADAC0D4DC" modified="2024-05-29" version="1">MNWTSYPNQNSKARATNTPVVSYSLSPPILKLLNTELGYADVFPQQKDQQEDILNETTAKFGFIDHDIIKNDNDSAFESLSEILKDQKVINQLSAFSGELFKAQNNLSEISNNSVFSPPARQLLSDQKRVNWINDLVQGEERLELIVINHLLNSQHLFILFSLRNLSKNVPHGYKNEKLLETLVTKKVSMVRAMKMKKRPDAVVDLARQWTIIVTAYLKKQLELIIKDKKYSKSRSSILNSPDTVVSPKMWNSYEDVFTECFNFELPTTMPPNFKEELSGTLKCLHHVIKKRNERLLLCRDFNNYSYSNIEYHQLNNFNCDMDLEDVFEEWVAYYGFEKTGLDKLEYAIHKLCDWSTLLKKLEEKLKLRNKLQDHLVHFLEVICDDDDIDACRVFHLFGELGHLRLFSYQMFLQRVISRGDLECFNTNEVKKAWFYRLLKELPLYNAELYQINLRRVTLYGAYGERCNSEDMMEENISLIKHHLKVLFPNIFNSIPASSITYPFRNAKEEFYVVLYKIMDLLNSKMKRYCQIKLCDWIKSHIYSYVVNHAGASLDNWKSNLTISGSLLNSEQYTTLINLFEQLEDIRSVVEVSIWTITNSVEREVFNYVLDSFEKHESAVFAMNKTIRLFTAVYDKHKELKSKSMSHLRLLQYSIHLLKTARIKTITANEANQLDLDLRSLTTPGRDVLFEAKDISELTDHNSWNTLSVPAINSKLKWKYSASFSANRDLYLKFVDILSSFQRSNLDRFELRKCMDLFCKILKDCQSQNGFMKQIIINDILNWKENIDKTTKYPQLNSHDETGYCWVVIWFSSLVANRCCSAIEILEKVCLPLLQQICSNFILLRLPLIVNVMSLTYQILANEDLLSQNFFQIYDIHTLKTIRLSEFRKENSLSICMKILDRTIKLQELKEKVDSQNISIIHLFKIRQDIIYSISMSGSWIKVLFLEDGVKMLKLLDSSLTSTKVNVKETESSNEILPILVLKTILVDTNFNAPLISNNEIIISMQEILSNLNKFTWKITKIRLEILLNHASSLQSKENKTLEKFTEALGDYIFELVVKRKLNENLLMCFIDSLDATYNVPYTVLKRFSILFRNLKSLAEGDSESTFDESFLWLKDVLMRKDMLDSFATFSGLLLNSLIEKTAKNPSSDNNLTNLKNDLIYICNELCESLQYLQKKLKQHEDSIISAPLPNCSLDEKESNIEELDFSKNARSWLYFFLNILVPFIPFIINNAKSCQLVSYVRCLIQLLTSKILYLHEDEELFSFLLDLVWWLNDDDYLMDELKELQRVLIIPSKSQGRINQIMPWKVNNVYTYNLNVVSLDKNNNLVNTNPFNLRPWEWLEDWAEPVTVSSKNTTPTAYLNNTPISLSMFGAVHVDVTKDLLTTEKFKGLPLYSRKQNHNFNQSYDCYRYEVLHSHSALDSSPSHITKSSDDSVPRTLYFNKNEVENYSMLNKLEHSDAHYAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4D0</accession>
    <name>A0AAD5U4D0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000523</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000112">
        <property type="protein sequence ID" value="KAJ3223927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4D0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000039">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000006">
        <property type="entry name" value="cAMP-dependent protein kinase type I-alpha regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003117">
        <property type="entry name" value="cAMP_dep_PK_reg_su_I/II_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02197">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00394">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 8 9" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="201"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="324"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="89"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="111"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="394"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3223927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="450" mass="50853" checksum="B05E55B89D9CF856" modified="2024-05-29" version="1">MLSTTALNISTIATKNPINSNKIGTPIQYTIPPGLPELLKSLNKEILREQPKNIYQFCSNYFNQKLNNKKFSNEQPLVKFALTQAVTENNDSNTVSNQNNQEANHSKDERMDEDEQNNETEEEKENEEGGQDEHEDDDDDDDDYEEMPPIPQSGNHNRNRRTSVSAESMAPTSGEAYVKVVIPKTEEQKQRIETSIKNNFLFKSLDEEQYMDVVDAMAEKKVMPGEDVIKQGGVGDFFYVAETGAFDVFVSRNGQPPVKVFAYGAGGSFGELALMYNAPRAATVTCTEESIMWALDRVTFRRILMENTSRKRRMYENFLEEVAILASLEPYERQKIADALESISFNDEEIIIKQGDVGDNFYIIEQGECRVIQIDENGVEHELPGLKKGDYFGELSLLTNNPRKATIVAKGRVKLATLGKKAFVRLLGPVVDILKRNVTNYHTFVKISLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4X6</accession>
    <name>A0AAD5U4X6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4X6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="111"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="513" mass="60076" checksum="38875E5CDD403464" modified="2024-05-29" version="1">MTTDFIEEWEKNFLIRESPDLFQENFSNLEETVNELNKEKQEDSNENSSLKNSSNCEPNANPNSNYPFPSQTDPKNLSQSYNPLGQGYFPQYLQPQYPLYSLPAINPPFLVQQKNNDISEISKKIIDLDRKESEQIMLKKRELLLKRHEKRLKDIQTLELKIKEKENKLYLDRLEKEYEKREKLTKAVICVQRFIRGKLCRRKIPDLRVNEIVKLNKPDYFILELCILELARDEFLPEVLVEIAEEMYYPFSNTTSFRGLRMWYHIIEETLSECILQSTREFLSDFAAEHLNCKPPPDPIEDIAEEIFSECVEESIKDVMQNVVRDIVDAHLLTNACESFYDELLREVLIETELVGKIFDAVIKMEGVMEDLIQESILDNLTEVIKEISKEVLNKNKNDIVKFKLKQKRKKGPLPIIKLTETKKKSEFVNFIMEKVLEKIALTTLLQIIATNGTSFFVSDIMEKILDHQIMELLISEFSSFENYFDEITHDIPVEKANEVALPAEKFGYPETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U547</accession>
    <name>A0AAD5U547_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000309">
        <property type="protein sequence ID" value="KAJ3220304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U547"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="70" mass="7851" checksum="434BF3D87B751309" modified="2024-05-29" version="1">MEAEKGVTPLAPSPPSIYGCLLGLEIETRQPSPSLRTLYWQRGMAPESQLLGDEKFLWQEGKVPFEFSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U583</accession>
    <name>A0AAD5U583_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EndoU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_004341</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ENDOU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000300">
        <property type="protein sequence ID" value="KAJ3220464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U583"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21159">
        <property type="entry name" value="XendoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039787">
        <property type="entry name" value="ENDOU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037227">
        <property type="entry name" value="EndoU-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018998">
        <property type="entry name" value="EndoU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12439">
        <property type="entry name" value="PLACENTAL PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12439:SF11">
        <property type="entry name" value="URIDYLATE-SPECIFIC ENDORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09412">
        <property type="entry name" value="XendoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142877">
        <property type="entry name" value="EndoU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51959">
        <property type="entry name" value="ENDOU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="EndoU" evidence="11">
        <location>
            <begin position="140"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3220464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="415" mass="48109" checksum="2B0C9CF509B728BD" modified="2024-05-29" version="1">MNSNKNDEKKIKPSAKFCGCFKKLLNFIKDIVLDKKEDKIKNPNITNSNETIQVETNRQKNQHSATNAWANGAPKFQTQQQNVKINQSELVETNAWSNGAPKIHSNVSSNQMTNSITEPQSAHIESLKPGILDMAPTKAELENVSLALEKLWLMDDNKLVPEKDFELNLQKYTYVSAQEDKAFEPLFKKTFDETKIFKSKKNFQHFINLLDNYTYLTGVKETNLKSHEKEEELFLSFILKTKPMLYLFHYLCELKIFKKEDLNNGVFLNKLKVVWFQNYKRVVKDDSSAFEHTFVGEIRDGAVIGFHNWVQFYLEEKRGHADYMGYIRPRDRSQKSSASDQILSIHLKWHNVIKPVSTLFIGTSPELEIAMYSLLFFTKNQNVKVTFDNVNLIFKIHTFNSPEGLKLGSCYVETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5C3</accession>
    <name>A0AAD5U5C3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TFC4</name>
        <name evidence="10" type="ORF">HK099_004141</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000286">
        <property type="protein sequence ID" value="KAJ3220625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5C3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03429">
        <property type="entry name" value="NUDIX_NADH_pyrophosphatase_Nudt13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049734">
        <property type="entry name" value="NudC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039340">
        <property type="entry name" value="Tfc4/TFIIIC-102/Sfc4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="9">
        <location>
            <begin position="102"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="744"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="761"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1173" mass="135986" checksum="6CF4EBA45BE7F77D" modified="2024-05-29" version="1">MEGVDKFTKVSYFALDASNLKTLVNHLETEGEFKAFRPTVFSLPKLEGAFVGHSRALLDWNASNIFCSLCGGETTSIEGGHKRKCESEDCLTHKGVRNVSFPRTDPVVITAVVSQDKKKILLGRQSIWPKNMYSCIAGFCEPGERFKFKYLKSTECLFSLEEACAREVQEETNVQIKNVQYQSSQPWPFPSQLIFGCIAEAETEEILLIDEELEDAKWFPIEENLEKMDDIENTFEDNEDEELEAFLPEDIEEIVRSTTNDLNVDVSNYLFKDEIDFKHYEEDGSKKKLKTTYLERRALTALPEEQRLRMGEANGEYMSGDVTKAAEIVLDILKTSPNYPEPWISLGSFWEDIHPKKSFAAYLCAALLKRKDADLWRRLYKASLNAKQTSQALFCLQKLVSSDPTDVEAIWDLSFSYYEQGRYHKAINGYLSILKHAPFNMDVIQEVVKIYIKVRDVHSAIALYEQVFDADKSFPLSKQQAEEADEEWDDDDEEVVSEFSLGSRMICPNFRMNYELLNKLAGFYLEIGDSERAIFVIKEGCRRLKGTSNCLNSDSIYYIADFDQAMADLDDTDEEFDIPGEPQEVWVPIQLRIQLGVSRLRLNQSQTAGKHFNCLFNYEPEKFSELYIMVVDAYMKHRMYTNALQILNYKNEMDNESCILTCSKMAECHQNLGNLVTCAKLLELELDPNDNENKLKLAEAYEDLGEDEKALVLIGEVDLASKLSANVKPKKRTHSRYLMKKKKVLKEPQQNMESEKSDGSYIEEEELDETSEEMESTINVEGMDSKAERNRKNFEKKIFEAERIKENIKESEKLEFLYNKIFKDRISMVNYLRTSRNLTSKFISHSYFFNKKDKRSTSFSNIEKYYVQTFFPKKVDDENTGEQKESTMFQGLTMDRWYEIFFKQALILTKTGRSEDAQQIFNVMSDCHCFNYNEDRRLTLKLHQLASAVYLKDYYRAVEVLRWLLHVKCGFSDIFRLYNATFNGADGKSVPIYASAMFQKFLHREMKLKIEKNIEDPVFFIFYGHHAVMGKSYEQAIGFFFQAYKSVPDDPMLNLSIGYSFIAASLSRRCLDRHMYLLKGFTFFFKYFDVLKSIGKEQEAHYNLARAFHQTGNLFLAVPYYQKVLQLSELPSNSSKNESFDLKYEAAYNLHLIYCSNGSYGLAEYILKQYCTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5C8</accession>
    <name>A0AAD5U5C8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000133">
        <property type="protein sequence ID" value="KAJ3223362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040401">
        <property type="entry name" value="CCDC162"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33331:SF13">
        <property type="entry name" value="COILED-COIL DOMAIN CONTAINING 162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33331">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1288" mass="150881" checksum="39AFDABD0E056FD1" modified="2024-05-29" version="1">MDQNAINEYIEKDLIDFEFLDEYSDNHPPESIKFLDKKIDEMVGNIASLLESRKKDFQNTPGRKDRLPVQPDTNFYENYQESRKEKLKDALHVEIPVQKYTSSQLVSKQLEIYWDVNKEFRIDNIRKLLRKSTSEPTKYKLQFQKHVQYLKKEFLDSIDRYERINECVVKKDALIKEAAILKQKDLEKNERLGFAVNRRSSMKPMIEKGNEKEDKKNITPVMREVTEEIKLEANDLEVGDLAIYLRHLISTYKPIQTMDLFLTRAKMLSIADREYWLKDYHLISHLKPGVPNDLPTYKFEGFDNFTEKFPLKNPRLEDFLNEFETLVTAFGIETQIGREDGRPFAFEIATKFSKLFSLHQKENLLPPYDFYFEDLTFSNSNPNVIQPASSEIGRGTKKPETYNPRINWSDLMDEKTRATFINPTTLRLRQADWLDQNEYFPRLEIWQERQKAILQSQKEIDFEVGYEYDLLLCNDIEVVKQKLREAAKGLCEIEDDSTYRKNKVNLNKQQGEETETDRISEFEECLRNKKPFDYGMLITDSRNTNEVDIVLEAKRTLCQKNEEIKRIEQELLELDPTRAGSVGQQIEPATVSNVFAEHEIFSFLLLKDLKIREHRSSLLNQLNFFRSIEKRICHDTKFLQQMKNTTFTDHMDKPYQGNVKVASFMSNMWKNQYFFDASDQSFCETSSISSFLDDIRIIHNNKIFVMDSNDTRFIYDVAVKDLKELEKEIIKIATIFINSDSLGNEKVSKKYMETLKFKLADRRVDSTVSTFYNPEIDRAQLLMELYDYECKFGNAKVQLVNLYMEALEHTTTFENSKKLSQIIIDIIYLRPNLNFKSKFFSKQYLYHTKALLSQGDTVMKILKHHIKENRGVINKYFFKLHKAMLDPDMEYPFELTDDKENFDFSKFIDTPLTIGLPLKPEKEKEMITMHQSGVSVFFGEFSSALDKIAEVYECSRYCLVEMSQALEQITSNDSTDLGSIECIIWKNFNTIWSSFALQNFESWKSKKIDRITSYENESGWFENPLFPDAFLSEKYSLFKSNQKEQWNKEGLFSAFTMFNDPSFQTKGCSFLINMLKLLTLKKRLFLTGTESEFWKKTFENQCLQMGVSKKGIVGKLCPLKFDLLDFVDIKNLDEDDIECGESDGEDEVFEQKSVEAFNVSLKCGPLAISEIDESLGSLAGSSFSEIFDALKEPFLEKLSRALKIQLIEMYNCLAVSQMNSHILCEINLKYLTEGYPSKEKKMALKKKPNGKDTIELQRFDFDYKALIPSLLSKKKFVRKCCLQEYVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5N6</accession>
    <name>A0AAD5U5N6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000110">
        <property type="protein sequence ID" value="KAJ3223974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5N6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="194"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="344" mass="39305" checksum="6662E8ABFA0B1864" modified="2024-05-29" version="1">MTTAENLDHLCNPKLPESIPLIDFSDYNSTDLQKKVNLGKKLVDAFSTAGFVYLKNCPLDNFDRDEMFKTSKEFFAKSSDYKVNLEWESAESNRGYVQQGREKLTELDKVGRADEIGLLRQVSPDIKETFEIGKENPNGKFQNRWPDDEFGKKFKSTSLKFYDQMHKINVEIMKLLNFGLDLPEGYLDSFVTDGDNNLRLLHYPSVEKKTLSKENKRAGAHCDYGSITLLLQDMSGGLEVKDYKTGEYVKATPIADTIVVNVGDMMQRWTNDKFKSTLHRVVKPYISEDETTYPARFSIAYFCNPNFDSIIECLPTCVDEGNPKKYGPISSFEHLVERLSSTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U602</accession>
    <name>A0AAD5U602_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ferric/cupric-chelate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FRE1</name>
        <name evidence="10" type="ORF">HK099_000160</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000102">
        <property type="protein sequence ID" value="KAJ3224169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U602"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF69">
        <property type="entry name" value="FERRIC REDUCTION OXIDASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="569"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="301"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="689" mass="79345" checksum="A522A693030844D1" modified="2024-05-29" version="1">MTDPLTKKNSLNYPKYVINFGLLLIFAFTVLYYVVYERHDETKKIPGYVQSPDIVNISFYFLPLGILIALAQIFTPLSPPQTTTQEFFNRKITTHIFAINSIGKLLFFILMIAVNIFWWFAPILMRDDLHEFTAVDWLSRISLKAAIPGMWDMALSIIFYCRENRVLSYLMKDIQGKNNIDETGLHFHKIFGVISFTLIALHSIGYGVVFYIEDELERLVPLSRKGLLVFFGIISWAAMIFMIATSIYLIRRKYYKLFFWTHQLYIVAIIFAVLHDSAVIYYVIPALLFLVYDKFAPRITSSEFRNAIAKIYSIDESIVRLDISLPGKQDFPFYPAGSWVNICFPTISKLDWHPFSITSLHDDNKKIVTIIVASKGKWSKKIFDLTVEGKTVEVPIKLNGYFGSSPHPKENTRNLLIAGGTGVSALIPFLAGFDLSSLNFVWVLKKPSDALLYTEFLLDLKKAASKSRFKPKFYCTKSTEIPLKIHEETRNIIHRYNTSRKRTSTSKTIYTKHYKLAAISMLVFIFGNLGYMIGRWIQISPANFARCRNFQTGFYMHFMCYYWLNGGPLLLSVLFPIVIGTIATFLFNKASRSKETPSNVDKFEIKEKAITRQLDVDFHNEVENTLNFLKENVCKGRPNFNDLPHMFPNNSEDDRKLYIYVAGPPGFNKDVENACKKNRIGCFVETSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U612</accession>
    <name>A0AAD5U612_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000096">
        <property type="protein sequence ID" value="KAJ3224333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U612"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004177">
        <property type="entry name" value="DDHD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF10">
        <property type="entry name" value="LD21067P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02862">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01127">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51043">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDHD" evidence="2">
        <location>
            <begin position="121"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="326" mass="36618" checksum="0DDA4E6BDC8BF531" modified="2024-05-29" version="1">MLVSDVILDLLLYMTPKYRQSMIDHVTNELNRMYLLFKSRNKNFNGKVSIYAHSLGSLLAFDILSNQKPAELDKKNSIHRNRTEKGDVDLGVLLHTIVSGENDSNTLSGSISDTQIKYNNLNFNVNKLFSVGSPLGLFLLLRGELLRAYIPENDANFKREKNHGISRPKVNSIYNIFHPHDPVSYRLEPLFDTKFSEMKPELIGYTKGGLKGKIVGIQDLSNDIMGRGFTMLNSIKIGVTSATTNVVNTVGSVLSANSSRKNSLEGVDFRNPMTLEDSPKAENSSNIFRDDDITNLNPRGRLDFSLQEGVLENPYLTALAIHMNYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U699</accession>
    <name>A0AAD5U699_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000223">
        <property type="protein sequence ID" value="KAJ3221559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U699"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041951452" evidence="2">
        <location>
            <begin position="19"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="433" mass="46891" checksum="62DD1D771605D6A1" modified="2024-05-29" version="1">MKIISLTIAIVASFTVQSQQISQLGGICLEYSADGGHVCAEGLFCQLQRPSADEGGKCVKPPKSVGEKCNRKNRCHVGLECKAGVCAQKISSYGEVCDEYTAGGKNTGHVCDEGLVCQEKNEVLLDLGGHAENGTLGWTNEVGLVGNYAYGSGPAKNPATFATSKTFNGNFGSYAFSGSLPAGDGSIQKVVVSQTFQLPSDALIEKNIGHVFYNFTSSFVFRQGDNDYATVNYTWLDQNGLPLPDHVMQGNGSNSNVLIGEYFGFTHTDTGKAPIGINFLKVAMTFYVSTAASLTSTGFVDNISVQLEYHQFIDRTYPPPTTPRLGYVPGQKVDPPLSQTAWIGIGIGGLGVLLLFCFVPFFTCFKKETAPILKHFSLKRRNTSLRNSLRRKRSEARKTKNTEAEINATKNAKVRKVRQKKTVLAGAPNDYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6A0</accession>
    <name>A0AAD5U6A0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Peptidyl-prolyl cis-trans isomerase cyp8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CYP8</name>
        <name evidence="14" type="ORF">HK099_008334</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000090">
        <property type="protein sequence ID" value="KAJ3224535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6A0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16663">
        <property type="entry name" value="RING-Ubox_PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026951">
        <property type="entry name" value="PPIL2_U-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04641">
        <property type="entry name" value="Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="13">
        <location>
            <begin position="16"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="11">
        <location>
            <begin position="267"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="12">
        <location>
            <begin position="355"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3224535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="551" mass="62353" checksum="6BF4E062BF5E1AA5" modified="2024-05-29" version="1">MEGGGAKKKPTHSQFKRLPFNCCALTFTPFEHPVMSIHPESNIATVYDLTSIIPFLKKHNVDPCSGLPLTHSDLIKLNFEKNSEDEYICPITFKVFNDHSNIVAIKTTGNVYSFDAVEKLNIKVKNWKDLLNETPFKRSDIITIQDPHNLTNKDISSFHYVKNNIEVKENKEIIFIKSTSGTSDRVLATLKKKEEEESQHKNNVTKSFVSKNDNYNAAPFSTGKTSASFTSTGVSVSTKTDAFLYSEVDYLLQNIPKSKKAFISLKTNLGDLNLELFCGDCPKACYNFIMLSKRGDYNNSTFHRVIKNFMAQAGKTKENKSIYGKDFEDEFKPNLLHDKRGLLCLANHGKNTNSTHVFAKNEMLKYGWQDGTGLGAKQDGIKKAVKVDFKNDTKGVGNKDDWSYAWWDHAFNKASSNIIIEKDDTGDIKINAKVKRIIKEEMTIAEVKNEKQNFLYSSFVKSKTAAEIEETEKDYSIKVSDKELLEACEGRTARKGARVEQVEKIRRVEVFGELDNNVNADIKEGETKLSLKRKTVENDDIDEKLITTGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U782</accession>
    <name>A0AAD5U782_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U782"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="96" mass="11184" checksum="70868543741C52A3" modified="2024-05-29" version="1">MQSETSKVEFEVQDLLQKLILASQEKNDDKIFNLKNNLIPLLHNLNLPTSSSELEQLKLEKDNLLQEAKNKANLMKYFIENLHETQFVLDVLLEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7S2</accession>
    <name>A0AAD5U7S2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7S2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="438" mass="49706" checksum="0772F80F411670A1" modified="2024-05-29" version="1">MQSSRKNSTNELLKILEERKKLKKCSDIHEAERQQEGLNVYEIDKKHNLIIETPKKHQINESNEQRVEEASENKKQTVSLEKAELHQMQNIKKAKKIQIKQVVVQRKSAYESKSVPTSPKQARESFIKKTEVLPKSCPAVRRNLNSSSSLLMKKLAFEGLLDSFGAENKQPSNKQVAFVADDNVADESVKLRQLKQTFKNIRSIDTYDHSTISSSIKPNLPPKPNSKANADSLSKSVEEIFVGNFIGYNKNNYKENQEYEKKGGPPPLPRKPVGNDIKTKPELPPKPSKVPQECKSLDSLTLNPAKKPPNLPPKPNKIYLPNDNETKENSPLNENVKPLILPTKILLTKVAFKSEDSLWTEIKKKEIDNSCFYKNQQPLFLKKSKKNFDSHKTLKGLDFNKPKPPRIFHILKKKTNIRLSVGDSAIGNSCGLICEKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U840</accession>
    <name>A0AAD5U840_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U840"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="647" mass="75556" checksum="AE7D107829A8EF54" modified="2024-05-29" version="1">MQERIEQFFINRPENTEIEARFFGYFAKKDSMVRVLEKYQSNIINISYTECRCKSSTNKNSTYRLRNNVELTCKTMLIRENFEDMWFNICVSSEEPVDITRKDEIFGQHPELIHINRYRIVYKDCYIDFGENVEVEITPQSTSESLYEAITWIIKELQDSSEIVTKTTFSMINNIKKSIDIVKPVTLTRYNVDLLEKAICISPKYDGERRLLILHGGKTIDVDMTDKIRFLDIPYRGMENVTVLDCELIADQYHIMEILIFNGKNLKDEGFAERIQHRENFGFHVKEYYLLNKLEDIMELYKHCTNPPAGHSINMPIDGIIIVTEHKILKWKPIITVDLRFSDNVPEKYQGWKIVDTNRNSSTGSLLTTNLLAGSVPLNIVCEFIINYKNRTLTFYRPRPDKAKPNSKKVFDSNTKFPIDDNAMKGIGFLFLRQYISLEKSSMLSTVYNNVKDKVLIDVGSGIGNDVNKWKTLKYKKIYCIEPRKEYIDIMYSRYGKSKNITTICDYISGYDNFSKRLPKASDVVSLFLCMQLFTNHDFEGLGKLLMSNLKIGGKLIGIICHNVEDYNDGILTCRRDNAFYTLTMKGTSVQNSRENIIDVDYIHSWILSLGFVNDFFVNIENRKYMPQNERKVLGWYMKFQYTKINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U870</accession>
    <name>A0AAD5U870_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GPN-loop GTPase</fullName>
            <ecNumber evidence="7">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GPN1</name>
        <name evidence="8" type="ORF">HK099_005221</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Binds to RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U870"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17870">
        <property type="entry name" value="GPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000579">
        <property type="entry name" value="GPN-loop GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030230">
        <property type="entry name" value="Gpn1/Npa3/XAB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF8">
        <property type="entry name" value="GPN-LOOP GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3228211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="241" mass="26973" checksum="1A69ECBBE05D9698" modified="2024-05-29" version="1">MAGSGKTTFMQRLNAHVHTVKKPSYIINLDPAVTHLPFDANIDIRDTVNYKEVMSQYKLGPNGGILTALNLFSTKFDQVLNFVDKKSSFLDYVLLDTPGQIEIFTWSASGSIITETLAASYPTVVCYIIDTPRSTSPATFMSNMLYACSILYKTKLPFILVFNKCDVVDNQFAIDWMTDFDLFQKALENDTSYMGTLINSMCLVLEEFYNHLKVVGVSALSGSGMTEFFDAVNVATKEYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U877</accession>
    <name>A0AAD5U877_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ER membrane protein complex subunit 7 beta-sandwich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005962</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U877"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019008">
        <property type="entry name" value="Beta_sandwich_EMC7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039163">
        <property type="entry name" value="EMC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605:SF4">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09430">
        <property type="entry name" value="EMC7_beta-sandw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ER membrane protein complex subunit 7 beta-sandwich" evidence="7">
        <location>
            <begin position="19"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3225906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="200" mass="22376" checksum="E04B4291C743FF08" modified="2024-05-29" version="1">MKNKVTIEGSLAKDDDLYLDASTRILLNYGERTAYLKSDGSFKFENVSLGIHTLTASSTLHYYDVIRIDVEENANSEPSVKASLSIPGATFDRRGPDLVYPLELKARHKYDYFLPRPTFNFFDLLKNPMLLMSLFSLFMMFILPKLTANMDPEDLKELQGKQINTTPSLPDVGGGLANWLSGADSSSSPSSPKKLEKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8A0</accession>
    <name>A0AAD5U8A0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8A0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042578">
        <property type="term" value="F:phosphoric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF1">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042181932" evidence="2">
        <location>
            <begin position="22"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="223" mass="24893" checksum="3802B7249CB5CB5E" modified="2024-05-29" version="1">MALKKVLKSLIFFQFVQFSYQVPAVSSKIKTVVVTVLENRSFDSVAGFFDYDEKIDGILKITPCYNAVANNTNSQKFCVAKGLKNYVPFGPNHSVQGADHQIFGSNIRQDIPASELPSSPPMNGFLENNLNNFDVKDAQSYVSSFDPKTIPVITTLAKEFALFNRWFSSIPGPTQPNRAFVHSNTAAGMSDNDEKKMIAGYDQRNLYDILMENGYTVGNYWGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8F0</accession>
    <name>A0AAD5U8F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8F0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="563" mass="64699" checksum="35F4BF38779FA463" modified="2024-05-29" version="1">MIENNQSNKFLNSNGYEDSQIARLNPVDSNKLLKFLNKKNKNHLEKFDSEITLKDENKSYIICYFGFEGKSDVDVKYFTFSLIFCVVYNFIIVFDKFYLNGYFGTEIFVLVAFNLFNIIQLGLGLFNKFKEKKTFNSKLPKKGNTNASTNLWLKISIFINLITNIVFFLISYLNYFVSFCLVPLGVLIWMSTQITERYYESGLSRLISKESWKVYDEETGDNKLKLINSKRHVTGKNMFNAINNFENISNTLEINSKFYINLDDYAGDLKYLMHEISDRDGILILNTGASVSKLEQEALQLCKNSTVIPLLVIASDNFENLFSLSAKFKNLVVAYDEDTKIVQTLIDVNFNSWQYSTVNILSQFSLILNPFLPISSNNREKMIIMSVSDPKYSFSWGSSKMKEYFQLYALRIGASAVISDVPQQFSIVDNAFDENLNFRETQNFNSNLTINNGEVRASDILATSLPLTEHEMEFQAKVEFQIEVLLKCEEDRIKLKQDMNGPLLFKNMDLDEKLFNGLSEELFDPTSLLMSGAVGMSVVSVILWAMARYFLSVSKTSVRVYNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8R4</accession>
    <name>A0AAD5U8R4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GMP phosphodiesterase delta subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDE6D/unc-119 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000110">
        <property type="protein sequence ID" value="KAJ3223976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8R4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.50.40:FF:000003">
        <property type="entry name" value="UNC119 homologue, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.40">
        <property type="entry name" value="GMP phosphodiesterase, delta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051519">
        <property type="entry name" value="PDE6D_unc-119_myristoyl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008015">
        <property type="entry name" value="PDED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037036">
        <property type="entry name" value="PDED_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12951:SF1">
        <property type="entry name" value="PROTEIN UNC-119 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12951">
        <property type="entry name" value="RETINAL PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05351">
        <property type="entry name" value="GMP_PDE_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GMP phosphodiesterase delta subunit" evidence="5">
        <location>
            <begin position="50"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="206" mass="23921" checksum="4E39F202817512C6" modified="2024-05-29" version="1">MAAILKKHKIKSDEDVRGNKEKTFTISDILKLKSPTSCFLSTNKVGSSLVQFTEFKIRDLVSNSELFSVKKNFDNNFFKSLEKGETTIEEFGDADRTVHYNFSKDFFKLKTVGTTLVFQIGLKEIKSFRMIEKHYFKNKLLKSFDFNFGFCIPSSTNEIETVYDLPKLDEKTIKEMIANPKQTTSDSFYFVDDKLVMHNKATYTYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8V7</accession>
    <name>A0AAD5U8V7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000079">
        <property type="protein sequence ID" value="KAJ3224847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8V7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041949251" evidence="2">
        <location>
            <begin position="19"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="19819" checksum="873116DA59CA42C4" modified="2024-05-29" version="1">MKFSTTIFLAFFFAETQCAIKDERTNTIKDQLKEFCDTKPESVDGTNCGSLKGAFSKAILAAAGFGGKECERTKIANQFVNAFPAFDQQLAANMCVTPVNQVFNVPAEIPCTSEKFIGNATPSFGEFGKVVQNNGEGAAPVGAVGPSSNSKKKDNSVNNETSGASQTRAEKKAAKKAKKASKQEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9T2</accession>
    <name>A0AAD5U9T2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GHMP kinase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_006801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000061">
        <property type="protein sequence ID" value="KAJ3225430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9T2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF1">
        <property type="entry name" value="HOMOSERINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861">
        <property type="entry name" value="HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00958">
        <property type="entry name" value="HOMSERKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="7">
        <location>
            <begin position="63"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3225430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="344" mass="36885" checksum="CE81EE7C5F592139" modified="2024-05-29" version="1">MVSYLIKIPSSSANIGPGFDALGIALSLYLTLKVTIPGSSGGITISCEGEGKDLVNLDPKENLITKTALQVAKAVSKTLPESISIHCKNEISLGSGLGSSGSAVVAGVCLANLALNLNLTKQQLLNFCLFIEGHPDNVSPSLLGGFISAYMREDFNFKKNDADSPTMDLLACSDKPIGRYIRLPISDSIRAVTVTPNFQLPTVLARKALPDVYPKADVIFNIQRVSVLIQALGLPDSEIKLKENSSLIFEAMRDKIHQNYRQHLIPGLPEILGLEQDSLEGLLGISISGAGPTVLALATSNFGKIGETIQNIFAKQNTSDGKRLDSIVRILDIDRNGVVIEQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA45</accession>
    <name>A0AAD5UA45_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003514</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA45"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd22979">
        <property type="entry name" value="DD_AK8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="61012" checksum="C9071EE1839A917D" modified="2024-05-29" version="1">MKKDTTPPLTSKPKKNNAAYADRNNLFQICHEMLSAVLISKPDDVITFFIEHLKTAKGNFTKKVFCINHLSTVPAFSILGPPASNLKYLAEKVAKAHDAIYISATELLINAISRGNSYGTQAKPFVERRQLVPDAIMTAIVLARLKDPDVQSNGFVLQGYPRTREQACSLQRAGIILSHVVVIDIPDDLVVERASGLRLDPQNNKTYHLKYDPPPKTPNTGQRLIQRASDTEDSVRSRLKLYRRNITLVSNCYKDNLRKFTYENGYFKQEDLVLKELLRVFGQGLNKIDYVPREFKILVQGLPGSGKSFVCEKLHEKYGIIHVSPKLVVLEELSSNSKNEFPDNQKNNNRFEDDVVLKLIVQKLKSKQCTEKGWVLENFPNSFSEAEALKKEGILPNRFFWLEVDKETCLKRLTNRFYDATNGKVFHTVTNLNLQIEQLPTLPNQNLIKNPQDSELKVKKRLEESEFLKEELLKSFGYKMDEKSKGIMQEINAVGLSVESFKESIDKDGFYDEEFIERSKEGNLLRPIPVVSRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAB5</accession>
    <name>A0AAD5UAB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Meiosis-specific transcription factor ndt80</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NDT80</name>
        <name evidence="5" type="ORF">HK099_005140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAB5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="59"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="59"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="424"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="435"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="482"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="493" mass="53825" checksum="22621A3B26C9C531" modified="2024-05-29" version="1">MEATYEETSNTQENQDQTSSSLANQPYMSEPYSSHAQQYYYQQAHQGAPDPNSYAEIDPNSSNELTVDPNAPIGGADGAPYDGLDSPGAAARKSRLNSEAGPFFNATKQLCNLYSIDRSRSFAARLTPRIDRGFFLADNDWTCYRRNYFQVSISYTAVDGAGNKVELPCLVELEGRGLRTVNQFMVGVMARTSNGSREIDLIQHTAKRDKGPQIVPQPKPCEPQDPSIAYGMSRNENDTSHTVIFERLQFKSATANNGKRRAAQQYHVVFAELLARCDDGCIARVASTESAPLVVRGRAPGHYASISGSKRNQMADTEEENYGEGNESGAPDYAQEYQSQQVNMLSAHGMPLPPPGSNHHMSYTAYTAPTAQSLQQQPNSHPGGYYPTVQQEYYYPYADAAVWANAAAAAAQAVKTGLDSEQPRFDYPYGMPGQQMLSDLTNSQQDGEESNGQLPTPQNVSPTSQKVGESSASANPPTSTSKPKKSKKDKVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAE5</accession>
    <name>A0AAD5UAE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAE5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="357" mass="40872" checksum="52F36DE961DC4F98" modified="2024-05-29" version="1">MGQNKLRRYQLNAIVDQVPNEENSTGMRKLFWTVIGRVIIDENVNRRICAYLKYRHKYYKNTSFLLKAEEKDAVDSIQKFISNHQEELDNELGNSLSKYAGEKEYREEEVKEEEEDVISQDDDDEYQKKRSLKTVSLKGSNVMESIIPKDVKDYLSQLGDDEAEFKKNVAAFYKLKQEGKFLGREKQYVLVQNQQIVGFFDNQIAAAESNEDEGGLIQPIDENKTWGGKKRCSNSVIVESTDDEYKDQFISVNGVLDSGCQTTTINHNHWNQMEPKPKKTPVRWSGIGDGIVRGSSIVVSRVKIPNLEKSLIGPLVIHVNPPQEAEDETLIRFDVIKSYWMLSVPVSIPNLIVAVSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB39</accession>
    <name>A0AAD5UB39_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003526</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB39"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000047">
        <property type="entry name" value="NADP-dependent L-serine/L-allo-threonine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="39254" checksum="5ED128713AC27B59" modified="2024-05-29" version="1">MSRLIGKTVFITGASAGIGKATAVEFAKAGSNLILAARRIERLEQLKAEFQTNYPKIKVLNLQLDVANKNLVDKTISSLPSEFSNIDILVNNAGLALGVDTIEDVTSDAIDTMFDVNVKGLLYVTKAILPGMKKRNSGHIINVSSIAGRETYPGGGIYCASKHAVDAITNTLRKELVSTALNVTSIDPGLVETEFSEVRLQDKTKAANVYKSLSSPPLTGQDIAETIVFTASRPPHVQIAAVTIFPTCQAACTVVDRKKARRISQDIENNIKKEEKLRQLEKKKGKAVKIVLLGTGDSGKSTVLKQMKINYGVEFNRQGIPEDERTLRNDDIEKFWNDEGIQKVFGRAKEYTLQENIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBE5</accession>
    <name>A0AAD5UBE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_005238</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF13">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8 12" id="KW-0518">Myosin</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="865"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="901"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1126"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1203"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1499"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1530"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1559"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="15">
        <location>
            <begin position="10"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="16">
        <location>
            <begin position="1793"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="12">
        <location>
            <begin position="646"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="789"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="834"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="110"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3228228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1852" mass="211162" checksum="23E70A12AC13E3C7" modified="2024-05-29" version="1">MEKQMGTFNVQNDLLLSPNPIDLDSIVNTLHSGYNENYIYCNIGTNTLIYLHKNKSLGLTSQKISDHYIEYSHDYFSKDTMLPSHIFSFAEKIYFRMQYEQQDQSVIISGDIGSGKSENRKLLINQLCALAKNKNVSKKVGHGSTLTESIKKSETIFEGIVESKNLKVIFFLKLNLAFGHAKTVYSLNSSRFSRYSELQYDGRGKLIGYKTLDYLFEKWRVPNGHHFGERNFNVFYYFLAGASNEEKAFWKLADPSHFHYLTKTQLDPEDFTKAAELKEHMIALGIGKQSQFEIFNLLAAILHLGNIQFIDDIENPQEAAKIKNYNDLEFTAELLGISASDLEITLTYQTKFINKELCTILLNTADANIQRDSLATTFYSLLFSWLVDRLNNRLCRDDCEIFIGITDFTGSSKNKTCSFEDLLVNFAQEKLKYFIMNRICNEQVNELKSDLVLSDDVSLENWGNFAELKFLTSSTGGLLSIIVTESEKFSGRTRTGQDISEMPSLHLAKSLFQNFADNPFYRHIEKKNEPSRLFSIKHFKNTVEYDTKGFLESNIDYLCPDFVAICRGDSGKDIKESEDPLIRELFSDGMVATRKHWKNQNVVIDATLLRRRSTRKPTLKRNTSRKSTAKGKHSIDTLLTSSQAAIDEIIDTLEQTVSWYIFCLRPNGLNDSDEFDVRNVKEQLERYELQKISEARLICNDLSVVIPLENFLTRFETIVDAVLSNTNTLKSPNSIEKVSIFCQRSGWDKKNYALGTTQQNIYLTENLWKSLINHLKVFKEKRKNERGSVVKASSSISQSNSDDDSDSDLSTANFSEESDEKSVVLQRRGTTRAQHTEIDEEKGKGSGNRGTLIEEKTLSPARKKWVFFSWCITFMIPNYFLNLCGMKRKHVQQAWREKVTLCFLIFLTCGALLFFVAGLGPVICPVQKVVSTAELQSKKSIKDPYVYANGRAYQIKAILDDHLSLYNINDTYFQSFLGGDISILFYKAPLWNYYCPGIENPLPSTWDNVYSRPVKQEYFPHNKIDPEKVVFTADYIKRKKTKKGKWISFNKNVYDISSYFTMTNKPFGNEIDQIFTSGLGKDVSDQVNALSIKSEKMRQVVNCMNGMFYIGGIDTRNSIHCHVSNYIILVSSVIIVSVILVKFLAAMQTGSYSSSEELKNFVILQVPCYTEGHDSIYKTLNSLALLNYDDKKKLLFIICDGKVFNFAFSIFIPFVNLGMIIGSGNDRPTPRIVLDILGVSLNVEPEALSFESLGEGDKRHNMGKVYSGIYDVNGRSVPFIVVVKVGKPSERQRPGNRGKRDSQMLLMSFLNRVHYDKPMNPLELDIYHNLQNVIGVKPSLYEFVLMVDADTEVFPDSLHKMTTAMIHDSRIMAFESLFGSVTCLPGCFTMYRIRSTNKKPLLIANSIIRDYSENTVETLHMKNLLHLGEDRYLTTLMLKHFPQFRTTFTADAQCKTVVPDKWNILLSQRRRWINSTVHNLMELMFLPRLCGFCLFSMRFIVFLDLFSTVVQPCALAFIVFLFYSATTGDLFPLVSIVLIVGIYGLQVFIFLLKRKWEQLGWMIIYLLAIPIFSFYIPIYSFWHFDDFSWGNTRVVVGENGKKLVHNPDVNKFDPRSIPLRSWSDHEKMDNNSWEHESQASSTTGKLSSVVSKVSSSTSVGNADHQNSTALNFGVQQRSRLPHTPNTYANRFVDHAHTSFQLPSIIEQPPLAVPISPIQTPLKDTSNNQDPFTNSSISALKINTSPIQSPSIQSPTELSHSASSSNSLIHFQSPKTEIQNTSRLNSPQITPTIEPTYPQLHFEINSLLNNADLMTLTKKEVRETLSEKFGVDLSSKKEFIDKCVDYYLLTNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBR1</accession>
    <name>A0AAD5UBR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBR1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="975" mass="113821" checksum="6AD17D816E69D4C6" modified="2024-05-29" version="1">MFTDSDNSNIAAVFCPILKCILCQLERSDIETKLFTTEEATILFNQSKKHHNLFNSVNYIFLNVTQIDENVRILMKLMFSELKYHEELQDCISTFFFKISYLKFSDKSLLCYLSIAELIAELDEEDLIQFKLKCLVEELVIDYFEKLLFPLMKNTFNEDNIRWCFKLLVSFLQPQKDSACCTAVIKNFCLNFCEDFQYFKALNRFLILVSHSIIHLALIRKQAEAGKEMEEEIIFHQEDESMTDNGGGIVNFLSWKFSIYDAFLWEVFRILSIFSSVSFDCAVLSYYTENFNVNYLKILQNSNLEYKTCTMVDSENNPNQKKFYSTVISLSVSFLFCDEVFFQERINSFYTESQIYAILTEFILGNEFVNLDYEVVLYLLHLYVSFEEKIFNKLEFRPMTYSKILSELEHTTKVKHLTTFQPEASLFSIWKCSEKSWSFKSISNLMTVEWIELLMKTNEDDGLDCILNNIVNVTITYSGAIDNILSTFSSSHSNGNIKMFYFKLFSKMISNKNYADETFRVPLLLGLCKIWISFIENDSDWKIVNLLLVEFLKGNFMDKIFNAEKKTLFQFFSSELKLDLSFLLKLMMRKLQLILDGDLVADEVEKAFNSVLGMLNFFNIYSSVEEGKEMVLKATSKNSMFTETLHKSFFVLEYHSALFPQIKVAAGMLLCLLVEDELLEKKQVKNYLQIEKIIYDLSKNLKTEWKLNSFVLNKILKASALKENNSLLNFIKNKNIEYFMEIFNSLRAVVFDTLKNPFGTESQGIVLTCIVDCMKILVDFLGELDPIAASFILNQKSNEFITTCIYDFWANYYTTECKDLRWNTSGFFDFILLFLQREAKFCSKIFYSINSNDCLIENFNLKALISILELNQSKQESSHKFKIFGSLISIFDSEINGEKIINKFSVMEKCKIKEVFNEVIKSTKESNEEAQQSNKFHWVNICENEDFFNQGLFILMEEITKVDLIPAMINLNSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBZ9</accession>
    <name>A0AAD5UBZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_005239</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08217">
        <property type="entry name" value="STKc_Nek2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000097">
        <property type="entry name" value="Probable serine/threonine-protein kinase nek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF10">
        <property type="entry name" value="NIMA-RELATED KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="6"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3228229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="382" mass="44108" checksum="956CAD5D490464D6" modified="2024-05-29" version="1">MNKNNYEIIETIGKGSFGLIRKVKRLSDGKVLARKEIDYKRMTEKEKRQLVAEVNILRELNHQNIVKYFERFVDKDKTIIHIIMEYCEGGDLANIIKRCKKEKKFIPEAVIWSFLSQLVLALNECHNGGSGTSSMSKPHPPILHRDIKPENVFLDKDQNVKLGDFGLSKIIESENEFAQTYVGTPFYMSPELINESCYNAKSDIWALGCLIFELCTLEPPFQSKTQLGLSAKIRQGKVENLPHQYSPELNRIIKSMLTVSHEKRPGTQDIMKVGKIRSYIIERELQQKMQELCLKEKELKRLEGSLKEKDLALKKREELIMAKEKFIVEKEKKFKVLISQQQINEETKISFQNNFSSFSSKGNSMIGFSNGVLVDSNFKENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRR0</accession>
    <name>A0AAD5XRR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002149</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001698">
        <property type="protein sequence ID" value="KAJ3201620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRR0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="234" mass="25646" checksum="F73A2E8846960838" modified="2024-05-29" version="1" fragment="single">AAAATVVTSATTLAVSALPTSVIPLPTSASLNIFTPSSIQQSLPTTSTSLPLPSTLSQASNLSSSEPNIFMKNLPVILVVIIALIIRKKQEQNLYPFLENRRHFSERFPKTATLIRNMSTRRTNTKREDENNQKNRGMTVTGTLDYKRGGKYRDSNNIDEESLIEGVEASGKDAALVEINTNNPRDRISNGYSFQVVDEPSSSDEISEEEIIEKPVTPPPAPPPVKKKLQKQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSK2</accession>
    <name>A0AAD5XSK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Yip1 member 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">YIPF6</name>
        <name evidence="6" type="ORF">HK099_000996</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001255">
        <property type="protein sequence ID" value="KAJ3204891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSK2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF1">
        <property type="entry name" value="PROTEIN YIPF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3204891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="154" mass="17031" checksum="080C2B69135E2D94" modified="2024-05-29" version="1">MSGNYGSALGDPNHNNVSVDQIFETTENSDLSTVSIMIPTHPEVSGSINSNQNKTKIERNHNLDTLDEPVSQTLLRDLKSIWEKLKQVLLPHKKENSLKDWDLWGPLLLCLALSIRLSITAKLDAANVFQTVFVLIWAGSIVVTLNSKLLGGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU52</accession>
    <name>A0AAD5XU52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000607">
        <property type="protein sequence ID" value="KAJ3214606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU52"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="63" mass="7160" checksum="4D1FE4AED31E3870" modified="2024-05-29" version="1">MSQPCNIDSSVLESFKKFRFKKLQDDTKLDCLILKIVADKLLVVKDSEFDGISLDDLKEELPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUI6</accession>
    <name>A0AAD5XUI6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosolic phospholipase A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PLA2G4A</name>
        <name evidence="2" type="ORF">HK099_002699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001912">
        <property type="protein sequence ID" value="KAJ3200410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUI6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47800:SF5">
        <property type="entry name" value="FER-1-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="114"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="264" mass="29215" checksum="85AB1B400524A9F5" modified="2024-05-29" version="1">MQNLTITFVSAEKLEKADGHLFGKNDTFLVASLTHTNSTLTHQTKTIKNDSSPKWNEKWSLQNVRAGSTLTIKLYDKDLLGKTELGTAHYTITDKTLKDETLALPVFLKKEDKSKGTVTIKVHSVPTVLPEVSVTILAARNLLAGDNSIVEGNLNDAYVEAHLDGEKFKTKVIDNSELPVWNETFKVKAPKVMSNLVCEIYDKDKFKTSDSLGTVQVKLVDLKSDLKQTFPIILKDGKKQGELDLKVNFSAVPDLTMKVVPVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUP7</accession>
    <name>A0AAD5XUP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001723">
        <property type="protein sequence ID" value="KAJ3201459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUP7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="32219" checksum="C57F4B0B73D82EB0" modified="2024-05-29" version="1" fragment="single">EKFPIKLLYKFEENVNQDREMEEVEDETNLTEDETDEKVKVKLNFEDFSLESDYLGSENEFAIALPTTGNSLNIKEKKQEGQRDIIDYVLNRKKRIKKEKTNTDDSESLKFEIKVEDSNRKEKKTRKKKKKTTPHRDRTTKIADYLKKLESKHHQESFESVKITSPASADKLNVDKISKPTRTSDAKSLFVQESVSNFDKNKSPDIVEKLDEIFFLKNEKDIVKTKIKFQDVLSNKNHTEEKNNEVTLAKVATKKKPTKSLRSKKDIELINSNKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUX8</accession>
    <name>A0AAD5XUX8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005444</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the esterase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000423">
        <property type="protein sequence ID" value="KAJ3217510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUX8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018738">
        <property type="term" value="F:S-formylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061:SF0">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0719">Serine esterase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="272"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="275"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR614186-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3217510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="308" mass="34151" checksum="FE619E582A652B5A" modified="2024-05-29" version="1">MSETSSSKVHDGCIKVFKHSSQVLGCEMNFSVFIPKQTTKDQQFPQLYFLSGLTCNHENFVQKSCALKRASELQIVLICPDTSPRNLKIEGEDESWDFGSGAGFYVDATEEKWKNYQMYTCKHCAICHSMGGHGALSIALKNPGKYKSVSAFAPISNPVNCPWGQKAFTGYLGTDKETWNKYDSAYLIEHYKNREVLNILVDQGDEDKFYKEKQLLVESLASVVNPSVKLQLRIQSGYDHRNNELLNKREDSDEINRKLRVKSAITYIRGKRGYGRGGKNNRGGGSSGGGGGRGGGEYGNGGIRSGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVA2</accession>
    <name>A0AAD5XVA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004944</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000366">
        <property type="protein sequence ID" value="KAJ3218761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVA2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF16">
        <property type="entry name" value="ATP-DEPENDENT HELICASE ULS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="215"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="309"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3218761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="485" mass="55799" checksum="131B7E9D62C22424" modified="2024-05-29" version="1">MLLDEAHTIKNKDSNIGKAVEHLNSIYRWCLTGTLIQNKIDELFSPLRFLKIKPYCEWSEFSYHIKRPFSKKSGMVSATARNKVQTLVKAMCLSRKKTELLDGKPLVVLPERIVNVNVNQFDEDERNFYDVMFKRAQAKFNKFRREGTIMKNYSSVLVLLLRLRQCCCHPSLATVFGDQIVAAAGDIVELEKLLLDGMPNDVVQRVINNNEQMECPVCFDAIDHANGKIIQMCGHCFCNECCDNLLTSTRLCPHCRGNMERDKILTLHSFLKKYNPSALKNEEEYLAKEEVVKKEDELLKKNDWVSSTKIEALISCIKKSMETNADDKIIVFSQFVGFLDLIELPLRKLGIKYVRYDGSMSTKTRSEAVEQLKKDKETRLILISLKCGSLGLNLTCANRVILMDVWWNPAIENQAIDRAHRMGQTKDVYVERIVIQNSIEDRILELQTQKQQLSDGIMGHGEFGNQRQTRLSIDQLMRLFRDQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVN1</accession>
    <name>A0AAD5XVN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000306">
        <property type="protein sequence ID" value="KAJ3220328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVN1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="63" mass="7049" checksum="618EC4159B8FDED6" modified="2024-05-29" version="1">MLVKLGTYCPSEETVEELKLNRTLVLMFLIGSLALFTCTLIYASAKSFGRSKGYKVINEEDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVQ1</accession>
    <name>A0AAD5XVQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000301">
        <property type="protein sequence ID" value="KAJ3220454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVQ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="65" mass="7670" checksum="79E2B05D1B6B2124" modified="2024-05-29" version="1">MFPLNFNKVHFTSFDSLIYNSVCLSKIKEIISTKDQLRLESYLNELNYDIINNAKFKVFGTFLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW59</accession>
    <name>A0AAD5XW59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein BIG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_003702</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BIG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000245">
        <property type="protein sequence ID" value="KAJ3221197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW59"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037654">
        <property type="entry name" value="Big1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285:SF1">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042288536" description="Protein BIG1" evidence="11">
        <location>
            <begin position="18"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="278" mass="31417" checksum="FD9EED94B70CB0D6" modified="2024-05-29" version="1">MKLFTVIIFSLFGSLFGLKNFPAVVWSSQPVEQPNSDDGVLSDIKSKLNDVGSCEKLNIIVWQKDLEADDFFVYENAFKSLKETTRENPSFIFPYQSEFEESIDDNVNSLEMISNYLKKQCFDNSASVGKLSFLDEEFPSFFRKPDILLLELPSFKANGYEEELRNLNINIQKVETVLEHVKILAGGNGYVFIFAGGEESFQRHGDLKKRSVESKADGKSNFAETKLKTLFEKYIFVNNGIYAGILGAIILFFTLIASINLVGSVQTPTRFEVKKKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWF8</accession>
    <name>A0AAD5XWF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">rRNA-processing protein fcf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FCF1</name>
        <name evidence="5" type="ORF">HK099_000627</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001153">
        <property type="protein sequence ID" value="KAJ3206085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWF8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09864">
        <property type="entry name" value="PIN_Fcf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037503">
        <property type="entry name" value="Fcf1_PIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3206085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="94" mass="10771" checksum="9857AF8E0CA3A847" modified="2024-05-29" version="1">MGELEKMGTQYRIALKVARDPRFERLPCTHKGTYADDCLVQRVTAHKCYIVATCDRDLKRRIRKIPGVPIMYLGNRKYQVERLPELGGAHGAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXB5</accession>
    <name>A0AAD5XXB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldose 1-epimerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000785">
        <property type="protein sequence ID" value="KAJ3212319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXB5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose, Leloir pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018052">
        <property type="entry name" value="Ald1_epimerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091">
        <property type="entry name" value="ALDOSE-1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091:SF0">
        <property type="entry name" value="GALACTOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00545">
        <property type="entry name" value="ALDOSE_1_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="32525" checksum="8F1A37505C96609C" modified="2024-05-29" version="1">MNLILKSEHAEARFSNFGASLTHLIFNSKVDVVMGLDDPDAYETNSPYFGVIGRTCNRTENGRFELNGKTYQLAINNGPNNLHGGIKGIDKYFWDSKFLDLNTLQFEHISDDMNEGYPGKLLIRVSYKLVESISKEGKVTVTLYQSFLAKLIDLEDPTLKTVVNLTNHTYWNLNGFVKEALEHEFEIPNENGRTETNKDQCPNGNIIKDLPDSPFSFLKKKSLGKDYDKVQEYRGYDHYYLIKEDNSTNKDLVLGCKVYSPQSKIGMELWTDALVSFTTINNFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY10</accession>
    <name>A0AAD5XY10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000603">
        <property type="protein sequence ID" value="KAJ3214635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY10"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029147">
        <property type="entry name" value="CFAP77"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28617">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28617:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14825">
        <property type="entry name" value="CFAP77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="335" mass="38314" checksum="53C76485BBAA491B" modified="2024-05-29" version="1">MILSKLKKKKKNRETVYDLPEPTHSYGKMEFRDPESVASSVIQQHRSKIPEKVTSPTLDYVTMNKNAAKSSIIDAKNLSKFRAENPVCIKVPQSNSERSSQIHLPSDNNPNFTYGLPTQSGDYIGELLTTKFQQEWQKEQENRDEEKYKAELENLKKKHTRVLVVAKQQHPKKESWLDKDVSTLFKMEKFQLKEAKISCWRPSEKDVTDKKFISIPPPSTKVLVKNSRVHGVAKVKSLKSNLKQLSIKNLVGVKITFGTEKCRFRGPLNSFYCNHLPSLYNESKNIKVETTEGAVSGLEVEFEGTGYVPVDLNVKNSTQIWERVNHMSSSKDLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY29</accession>
    <name>A0AAD5XY29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000340">
        <property type="protein sequence ID" value="KAJ3219404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY29"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="78" mass="8541" checksum="F18837427B4FF544" modified="2024-05-29" version="1">MQQSASSVTTLPSQASVTTTPPQKKPITRCAQDTCNDRAVKIIVHVCEGLIKCKQESISKLSDKLQSERIQSSKIIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY85</accession>
    <name>A0AAD5XY85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Methionine synthase reductase</fullName>
            <ecNumber evidence="11">1.16.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_004432</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.8" evidence="11"/>
    <dbReference type="EMBL" id="JADGJW010000310">
        <property type="protein sequence ID" value="KAJ3220230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY85"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030586">
        <property type="term" value="F:[methionine synthase] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000059">
        <property type="entry name" value="5-methyltetrahydrofolate-homocysteine methyltransferase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="13">
        <location>
            <begin position="8"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="292"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3220230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="674" mass="75165" checksum="C0E979D0688D93F3" modified="2024-05-29" version="1">MTNNYSSISVIYGSQTGNAEWIASHIAHQATERGYSSTTSTLDEFIATNLALTSLLIIVISTTGDGDPPDNATKFWRWFRRAKKTEVESFKGRKYALLGLGDTNYSNFCNSAKRVDRKLTDLGAEPILPKGLADDATGLEAVVEKWIDNLFQILPNFVIIDEEKKKLFDAKVAIGEINANAGLLTLKSNNEDRKEEEASVKIVKEETKITIAHTNIQDTKLNTSVSFSAKVFNLPQEIFESTKAVKGLAKLPTEFLKVIPSQLKKKPNQSTKNFLSLILSKELPSTVGPSITAPTSGKITRVKKLTGNLSEKKIIQLEIDLSSGTMSEVEKLSPGDAVGIICPNSDELVLGVLKKLNLDPEEVFEIQYMDNASDKGSVQMLAECSSDETEKKWLLILSSVQGTSTLKSFREKNANLLDILTTFPNSTPNFGRLVENLLKLHPRYYSLISKNDTSKTITIGFNVSEFEDGFSRQLRGLCTGWLDDVTNKSNNREWEVLTSEVVIPIFPKLTNDFKFPINFKKLLLVTAGTGIMPFISFLEHVKKLKKEEQPEVWLLYGARYCGTEGDVCFENYLNDLKSELRSFSLNLCLSRQSEGDGYFKGYVQKFINCNANDVFNFINGDDGGCIYVCGSMNMAKDLNAALIDIINDQKLDVNGVEFLSRLTESKRYVREIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYC1</accession>
    <name>A0AAD5XYC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA damage-binding protein 1a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DDB1A_1</name>
        <name evidence="2" type="ORF">HK099_006743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000060">
        <property type="protein sequence ID" value="KAJ3225470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYC1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="1">
        <location>
            <begin position="94"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="492" mass="56614" checksum="D2E83FE5C2FCF6D5" modified="2024-05-29" version="1">MCNFRSKKKPNAIAIDMGSDFMMGEIDQVQRLHVKSYDLNGEMGFRLSQQESSQTFGVITTRTITKQVDLKGKQIHRSDSVLSFNQEEEVEEAFFKIFDDQSFEVLDSYKLLPYETGLSCNNLTLGESEDSLEDFYFIGTAFLQENEDEPSKGRILTFKIKKELRKEKKLTLINEILIDGAVYEILKLNYNKIVAGINQRVQIFKFFEEKIYKTISYHGQICTTNLNVLGNFIYVGDLVESVTILSYTPPSEEKEEQLTEIAKDTENSWISALENLNMDNVIGADSSFNLFTLKRQIDLYQEEGSEENNLNPLGLNNSSFNSNLFSGENLKTFGEYHLGDFVNRFRKGSLVRTDFGESYSLAKPKLLFVTVSGMIGVIGELLAKDYFLLKEVEKRMRKVLGNVGDFCHEGWRNFQSLKKKNHSNFKNKNFLDGDYLEKFLDLNVKEKYLICENLKYFKDDGEEVSEGSLLETEVFVKMEVLNSIFEGLKRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYD4</accession>
    <name>A0AAD5XYD4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006240</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Nibrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000525">
        <property type="protein sequence ID" value="KAJ3215722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYD4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17741">
        <property type="entry name" value="BRCT_nibrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22667">
        <property type="entry name" value="FHA_NBN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10980">
        <property type="entry name" value="Nibrin, BRCT2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040227">
        <property type="entry name" value="Nibrin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032429">
        <property type="entry name" value="Nibrin_BRCT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043014">
        <property type="entry name" value="Nibrin_BRCT2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162:SF0">
        <property type="entry name" value="NIBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162">
        <property type="entry name" value="NIBRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16508">
        <property type="entry name" value="NIBRIN_BRCT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="10">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="841"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="847"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="875"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3215722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="910" mass="104247" checksum="212509865D7001B4" modified="2024-05-29" version="1">MWFLTAKSHPNTIWLKPGWEGVVGRKKTVNLQFFAIKQISRIHATITTEVISEKDDIFDLEKLSKVKIMDHGSTLGTFVNGVKISPNEWVYLKEKDDINFGESSLTFCLLYKPIVICISNLSSNEKSEVADLAVEADMKISKAWTSNCSHLLMKELKVTLKVMFCLLMCKDIVNLKWLKLTANAKPENYIHAEEKDFLPESNEKLLTNFEPSYLPDEKRKSLMTGKTFVVFNEIQLDYFSKIVPLAGGKVLLRKQHNETETSLKKYLKEISSVCIIMPQSQNVALKYLISNVAARTLDENDIGLAIMSANPRYLISSTDATVAENENLGIHLGADSQVVDQYSVRSKISNNKSLPISYVDNKKEKLASEDSMSNELIDGPQIIEDGEEKKNFDTKNSSQTSLESLIRETPPFAASSIRNSNFSPVKSNLISQNMDDFWDNLIGGTSSNFIPCSSTDKNIKEEFNSTEVKKVEDKPTTENFTTSEENKTINNKKRINPFTIVSQNKRQKSIEKDDFKSFEAEKKTNTSNVDVLFNSEKSTSLSKDFLDDKIFKEELNGYIESKKFNKEKKEIEEKGKLEEEKNFKKKEKKLKFINTNQKKEKKKLKSSDLNKLKYKFFKNDDYDEAYSSDVDQSESDEDLDLSTLKKLTDITLVDLIPAQKKKENIEEEKKEGVNFKKFKKSSSLKKKNQNFELILHEKGNEHFIVGGIEEPWLKPKKIKQIKDYHSTIGKGKKKNLQAYSNEVDEKLLLSSGESDLSEVEEEEIEILEKKKKNFFSKKILLDEEEEDNIRVDIESNKDFTKADTKMTSQSSLRNFFNSKLSNSTGSNNSLSKSKNEIHSFDEMEIESSNNSNLENDLNTTTLKNNLKKKPKLNFSKITENPSQLIFSNNKSNQLKKYHLVDDDEEDNFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYI8</accession>
    <name>A0AAD5XYI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000494">
        <property type="protein sequence ID" value="KAJ3216164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF3">
        <property type="entry name" value="METHYLTRANSFERASE FKBM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="1">
        <location>
            <begin position="50"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="227" mass="25627" checksum="F9E913F43D6ED9B3" modified="2024-05-29" version="1" fragment="single">MDGSKSSEFEILKNEIQQLKFQLHTYQEKNNEQKVTISPDKAVFLQGRPGARNGIAQSNTYFYEKALGWKGLMAEVMEDEYKELVKNRPGSLTVNGAICAKTGTIEFAVSQIGGWHGIAGQITEERKNKNAKIITVPCYTLNHVIEKAGFLRVDWMSVDTEGSELEVLTAFDFSKVVIDFIQVECLTMEPEKMNGIISLMESSGYEYINSFVVADDTRDLMFRRSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYK0</accession>
    <name>A0AAD5XYK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000262">
        <property type="protein sequence ID" value="KAJ3220942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYK0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041960509" evidence="3">
        <location>
            <begin position="18"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="405"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="456"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="603" mass="66496" checksum="62791106F5C3DB75" modified="2024-05-29" version="1">MKVQCIILLLLAMICVSMRDSSETKYANSTELEIYDPTISKSTELMTRGEYRLMKRGGSMGMGFLIAGAIILGLGLAAAVAAFGLFQFSLITAVTQASLNSFATLLLAGGGAFFAGGIAICATSGCSNSGKLMTISGERYIGNISQKLLLDPLVDISSNSSNTLRYTIRSIDGSTSNGYYAMFDSEGMLSNYTSETIFNDTNRNEEMARVSAGNGDKLSIHIYNWYVSNNCGANAGAIIREAVGNLASTLAGKDGQRSCIGLRYKGCNVAVLKIYIDSKENMWKAPSNHACTGEVTKYTEVYKREIRDGCSGCRQCGNCRDKVGKMISPGYIGMISELSDQLVGITEYSNIDSSRCTKSYYSNCNNFKNAGMSLHMTQDHHDNDVEHCKQNQLEYRLRNIHSVTVILIAFIVLSVGSIYMITSYNSMTGCVYTYISNRKKVDIDTDPSIQHRKIALLLAICIIFIHVILSISLFIVITRVAAPTKYYASYSIIGFEVFTVLAIYLTRKLSLSDKEDTEKYARSTSPVHNRTASKPPISPQNNKLTKAHSYRIIIAYSMHYAQRKPLPLRINQDNVSLTREPANKPSKYQINTKPPITYLVNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYK7</accession>
    <name>A0AAD5XYK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_005801</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mediates influx of magnesium ions. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Mg(2+)(in) = Mg(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29827"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000047">
        <property type="protein sequence ID" value="KAJ3225976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYK7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000004">
        <property type="entry name" value="Magnesium transport protein CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46494:SF1">
        <property type="entry name" value="CORA FAMILY METAL ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3225976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="494" mass="56140" checksum="6916F04B2005546C" modified="2024-05-29" version="1">MINPIAEVSTTSSNENLTLNEVEDPAKCEVPKHSKFKKAAHKVMRIKRVTKLDRNLLLGNSSGVDLKLPPSYISEIFTLTNISVIDYDQESYKYTALENETLAKFLQKERPAFSKVRWINVQGISFDVIKILGEFYNLHPLALEDIFHIPQRIKCDYYDGQLFVSMILLNLSENFVSENVNAESERGILTPFRRKQSFELPINSSSIDVPGERGLCSTLFGGAQGYLKQLGLSSKQLELFRRPECQVEQCSFFVLNNGVIISIFQNESEQITESLKKRLKPLANINSHPPTSNNAKKVEYPKSLLRKSSDVSILLHSLIDGCVDYNSLLLDFYAKQIDSLQDMVISNPKEIYTKILHLIGKELKMIHRALKPQQSLVAAISERNIDESKNADESLVTISKLAKVYFNDVSDQCIMVNEELQAFETNTKDLIDLTFNSISHSTNESMRTLAVVSVIFLPITFLAGVYGMNFRNFPEIETENGYYYFWVYTALSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ71</accession>
    <name>A0AAD5XZ71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Stealth protein CR2 conserved region 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008322</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the stealth family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ71"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047141">
        <property type="entry name" value="Stealth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021520">
        <property type="entry name" value="Stealth_CR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045:SF0">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11380">
        <property type="entry name" value="Stealth_CR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Stealth protein CR2 conserved region 2" evidence="3">
        <location>
            <begin position="112"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="406" mass="48629" checksum="F78B393A2F903D01" modified="2024-05-29" version="1">MKIKIHWQWKGSKFFVKLILASSLFILLLLRTNSKSHFLKKNGIVFIKSKDLYPIAKNDFERLQEQQDQELWGFAINCSVIYTWVNGSIKSHQDEFNKYRVKYGAHEKSFQRYRDNEELKHSLRSYAKHMSWHKGQIYLVVPDGHDLTIKVPNWLNTKHPRVTIINQSTLMDEEDNPTFNSNAIEQNFYRIPNISELFIQINDDTFFGSNLVYEDFFTKDRGNNIFMDNIKTDLEKHYNALWTSRQTTYRALINQFNCSLPMFSTRHAPIAFLIMHRLFKKELKETASRKFRNRYDLITPILHHYTVMNYKDDGEDSMTENSEPYRSGKGKLKFNFKNFKQEEMKLTHFFKPVTDNFESDLNSFKFFSEYKPKFFTLNDDFESESVHYLMKLFLFNMFPEKSPFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZI8</accession>
    <name>A0AAD5XZI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Guanine nucleotide-binding protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GPA1_9</name>
        <name evidence="6" type="ORF">HK099_005560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000439">
        <property type="protein sequence ID" value="KAJ3217186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3217186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="220" mass="24858" checksum="9B4457CFF253D653" modified="2024-05-29" version="1">MKNKSKSDISMDPTAARTAANSLFPLDTSLNSDVLENSLTTYEKPPKTPKQKKKISKLIDSQIQQELNAQNQPLHTRKLLLLGSGDSGKSTLLKQMKILHGNGFDAKERITYRIALHKNVVDSMKALISAADTCGISISSQNLKNKAAIEDFNFDNNLELESFIWDAIDALWKDVSIQECYKRSNEFNIQDTANYFFRNVNQYRKTDYLCTDEGNVILSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZZ5</accession>
    <name>A0AAD5XZZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000356">
        <property type="protein sequence ID" value="KAJ3218998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZZ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="434"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="557"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="477"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="658" mass="74759" checksum="7A4BE0FE5FBC3D09" modified="2024-05-29" version="1">MSNQHSVPMSTDEFERILDNEVPTRITLSEQRRFSHDSDDNYSLNNNTKIEPYFEQTGISQNPSSKKTYDDDDFDSDLDDAPKKKLTDAQSLAEFLRTTGPPEPRPKSPPPKKKKGTGLFKFGKKSKDDKKVKKEQTPQPEQNVKKHVPLTVAAGYFDEPMKQQPQVKNQQPSQRPNFNNQYGDFPQQQYVPDQAYPPRDPANIQGQIKQQQEVPEFGQRGPSLQTQKALPFPPDGNNSAKQQPVRYPPRQEQNMDLSFQNQQSGASEVIVPVRSLSMQAQTDYPNIYGGYNDGLGHDDMEDEMYSDEEDYELLEDQGFDEEMIRNTEYNALVDNSQIYTEETKPKGGRRVAFAQVDDEISNYEVSDEEDVEGSIEKTGLRPRGSYYPKPGMELENQLSDEIPMIKQRQSSLAYGPPPIEVTSASRSSSFAISAQVKNPGSGPIKQQSPQIPQVSLASQSPPLTTSVSKTPEIPLKQNQNSSNDQQNSPPMNTSSLTSLSNVSSTLTTDQVANKPRVKKKIRHVQIQTRGAITKEGSCQTEFTEEKKKIDLEEEAIVINLKKDNANLSELNFELEKNLENFKIDLIEKDNALEDLKFEMEENRLKFDKLSAHAYKKIKELLMERQMLDMEVSTLREQLHTLQDAQSRQWLENDEDSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0C6</accession>
    <name>A0AAD5Y0C6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein phosphatase 1, regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PPP1R3C</name>
        <name evidence="2" type="ORF">HK099_004269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000299">
        <property type="protein sequence ID" value="KAJ3220478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0C6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000164">
        <property type="term" value="C:protein phosphatase type 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001069">
        <property type="term" value="F:glycogen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005979">
        <property type="term" value="P:regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050782">
        <property type="entry name" value="PP1_regulatory_subunit_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307:SF36">
        <property type="entry name" value="GLYCOGEN-BINDING SUBUNIT 76A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM21" evidence="1">
        <location>
            <begin position="37"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="528" mass="60375" checksum="9D134BD07DE6E39E" modified="2024-05-29" version="1">MKKVSFTETNPIQTFNKNDSPNDLLGWKMKDSYHLLALPTPADYIKLSSIKLNKGIITGYVLVKNLAFQKEIIIRFSTDQWKSFQEVDAKFNITSYNNYDSFTFHLSLDEIFKTQLENFLKRKTSFTKEQETPCISFCIRYFTDNVTYWDNNEGKNYLLHFSFPTFSRTRYTRSYSDSFIGKIPSENNIVKDIRTKPAIQQTWKQQQSTLVDVHNYTNKLKKSSSHDSLSSGHWKKNFSPISSVDAMGSSIRLKRTTFEPWNNFKFTKLTTPCESSLSASNVATNLYFKPCDEEQNLVNFNLTGAKKVNENSQNDAESSLINLMQLSTREKHLSAFIKNPETRENPDSVIENINDVSSLRNFAVPIQKLLIPKEDGFAAPLPLIQSNNAMLENRKFISNFNAEPLTFNKSNENTKVNFKTSLLKEGLEKKNNSNPQVKVVMIIKDDLNIMQSKKDVYNLKNDFEKDINLVCKENTVSEELYSKGLDILPLCKRGASYSHSPTSSSCSSVSSLLSIESTHSSLNRNLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0D9</accession>
    <name>A0AAD5Y0D9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transmembrane protein 62</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TMEM62</name>
        <name evidence="5" type="ORF">HK099_003220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000214">
        <property type="protein sequence ID" value="KAJ3221697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0D9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056229">
        <property type="entry name" value="Ig_TMM62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019481">
        <property type="entry name" value="TFIIIC_triple_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14795">
        <property type="entry name" value="HELICASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14795:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24384">
        <property type="entry name" value="Ig_TMM62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10419">
        <property type="entry name" value="TFIIIC_sub6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="788"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="817"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="728"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="741"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="849" mass="98160" checksum="6FA2F355FE5EACC8" modified="2024-05-29" version="1">MDDMDIDENYEEEVSYQILNISNEVSKEELKNSELESGYAVIGLESETPYIRIGEHIFEGKLRKTIGTDLIFEKKEASNKKKKKEDVEVAAYSGFIRDKEDELIFVVTGDLTDAKDFKKLNSFQYIEEWEAYFDLLKLAKVLRKRNNTFWFDQRGNHDCFNVLNDDKKLNFFKNFSSVKSTSGYNFNLVKDFGVYNFVSLDACPKYGTTRPFNFFGYYDIEDMDHLSASLNEFHNHSFVMSHYPTSTTLFGKSSKGETFEQLSNLISVFFSGHLHTLFFNLGGKMFGHQGSGFLELELGDLKSHGFYRIVSVDNDFISFSDRTLQKDGEVLPLLALNKTNSKEYNFSKAPTYKENLNFKPVVLITNPKDNKFILEKREPVNKLSEFNFIRVLIYSPFSVDSVQIFLNGELHKERVYYHGIGKSMENFADETEPYLPLWISPFNFKELDPHSIYNILVVVNDSLGNTANASVNFRLDGKRTMGMGFGWFQEWVILTSFPRIFKDIFVYSYLTIMIGFLLVPKIFTSIKTKNGTYLDWRYKVCTQLKEIDTKSFKRSSSFFNIDSRQNSVVMEGNNDLIEGKKQEDSKVKPEIKNEKGVFFKLRSLSKKKSNVFKTPTLPSSNLKKCESEQEIFVQINFKNFFYKPLEENLMFQVNLAEEINEIFKAYDFYPIVQTSTSNFNFPNTLTQLSNNDFFKTSLESSTIVKLNSLKNNQTDLLSLQKTTTLSTHQSVNIVSPPPDSPASTGTSYSSSPLSSTASVKDNPNYFPDFQLPTEKIKKKKYSSKRKEKCCPDCSRIFKRPADMRRHKQTVHDRVQNYICENCGKGFSRADTYKKHILIEEKRKKKSSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0X7</accession>
    <name>A0AAD5Y0X7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L16B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL16B_2</name>
        <name evidence="5" type="ORF">HK099_006188</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000052">
        <property type="protein sequence ID" value="KAJ3225790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0X7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3250:FF:000001">
        <property type="entry name" value="60S ribosomal protein L13a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="155" mass="17823" checksum="FF696CCF5A363191" modified="2024-05-29" version="1">MVGSVKYLTYLRKRCVVNPNRGAFHFRAPSRMFYRVVRGMIPHKTPRGAAALERLKVFEGVPPPFDKQKRMVVPQALRVIRLAPNRKYTVLKRLASEMGWKYEQVVDRLEAKRKVKSAVYYEKKKSLAKLSAKAADKSVKELKPINEKLAAFGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y192</accession>
    <name>A0AAD5Y192_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000034">
        <property type="protein sequence ID" value="KAJ3226531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y192"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042141438" evidence="2">
        <location>
            <begin position="18"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="146" mass="16226" checksum="5A33B0C6FD90C102" modified="2024-05-29" version="1">MKVLNPFAILLISVTLSIPLKQKTGSSTTNDMSAKFPIYVVTTTPVPCSESSATQTSATSKSMEANSETKKSKIKESSESTKSKRHPEFDPYLVRSKPNKSDQQTKKDSVKTSESATDIEDCTEKETKKKSKNKKMIKKNIMKKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1P5</accession>
    <name>A0AAD5Y1P5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED6</name>
        <name evidence="9" type="ORF">HK099_000325</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000107">
        <property type="protein sequence ID" value="KAJ3224047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.580">
        <property type="entry name" value="Mediator complex, subunit Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007018">
        <property type="entry name" value="Mediator_Med6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038566">
        <property type="entry name" value="Mediator_Med6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13104">
        <property type="entry name" value="MED-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04934">
        <property type="entry name" value="Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="215" mass="25318" checksum="A8402F5C5CDF1980" modified="2024-05-29" version="1">MSKQNEEELLNVCFKDTNFLQMYSLNEFNVLDYFSYSQFYEKSSLNEQIKMQARFNELQANMLDRSLHYVEKAFADIQAECNFHPTKGYVWKNIEELEMKNYDELLKKIMGTKNEIEEELDSKEDCMISNGKELDVSSVTSTSRSESEEIFLVTSEEKAKDAKDFAFTVNQLITRSNEFASEFELNKLKKEEYAEKKKMQEIKPTEAFSNKEVCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2R3</accession>
    <name>A0AAD5Y2R3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfoquinovosyl transferase sqd2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SQD2</name>
        <name evidence="3" type="ORF">HK099_005562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000044">
        <property type="protein sequence ID" value="KAJ3226093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2R3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050194">
        <property type="entry name" value="Glycosyltransferase_grp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947:SF3">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13692">
        <property type="entry name" value="Glyco_trans_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="2">
        <location>
            <begin position="27"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="472" mass="53865" checksum="85CD6C25A287B6C8" modified="2024-05-29" version="1">MTFTIPIDNSRPLRILIATEYLPPYISGIANRCKNLISGYKRNNHHVTVYSLKGTDADHVVFSVPNVFYNAQRMFIFPPLMLIVQLLNPFKKVNYDIVHLFGPLCLPFVFLLPLFYLRGVKIYVSYHVFLRYYRDLYFTKWNEKYYGMNLLGDILEYLYVALYFLPFVFWADIVGVPSKTADWCVAKFCRNIHYMKSGLDSEIFKPIVVSDEMSYSQDDKKVLAKKSETKCDLFNEVVTKAKYSGPLLCYVGRLALEKNIIFLLRALLNPALSNASIILIGDGPERSILEKASMELVGSENVFCNSEKLNLSPKEILRISRNKRIVFVGMVYNENDVATYYSSCDVFVSASASETFGFTVAEALACGAPSVVVRSGAFASVYSMIDDWMYVENDTQDYVNKIVKCLNLGVAARKKSRNFAVEYFSIDAAIFEQLRAYKEVVFCKNEFGQKVMKFSSVNTEETLQESVSLIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3U1</accession>
    <name>A0AAD5Y3U1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3U1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="26853" checksum="B24D9A7A55C2FDA9" modified="2024-05-29" version="1">MQAHSHAMYTTLFPDLGCHNIILGFTLIFEMDEETFICCSKNLKREVANQILELKNEFQKTSNQIDAEFLKLINNYSNNFLDMKVSEFLTLYDGNYSIFLEKTTNLTSDIEADSYKKPSISALPASSEKEENCSELRQPVLSTPTANEKNDTTVKQPREIRSREVGIYSKNGTPLINKNKKDESSMYFDVPINDNGKYELVKMVNPNKLCNFKDHPQFDQIEKFFKQFHFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSR6</accession>
    <name>A0AAD5TSR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial oxaloacetate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">OAC1</name>
        <name evidence="12" type="ORF">HK099_002785</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001955">
        <property type="protein sequence ID" value="KAJ3200184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051508">
        <property type="entry name" value="Mito_Carrier_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928:SF1">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3200184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="58" mass="6707" checksum="BC27CCACF50CE4E7" modified="2024-05-29" version="1" fragment="single">VIKTRLQLQGELQLHQRELIYKNPFSSFSSIYKKEGLRGIQKGLGPAYIYQILLNGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTA3</accession>
    <name>A0AAD5TTA3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CTD small phosphatase-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CTDSPL2</name>
        <name evidence="6" type="ORF">HK099_002704</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probable phosphatase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CTDSPL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001918">
        <property type="protein sequence ID" value="KAJ3200381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTA3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000015">
        <property type="entry name" value="CTD small phosphatase-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="5">
        <location>
            <begin position="148"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3200381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="329" mass="38263" checksum="2AD3442C4BFCC7B0" modified="2024-05-29" version="1">MDIDEAGPDNEEGQINSKKLERSLDTIVQNQNDFYDKENKNNYNLNSNNINNSNNKNKKFMASSAIITSSFRNENINLDHQKINKLESINTFNCKKFEVKNINAVNNWTLNNIANFENIESFNFIRNLHNLNQINLSKRAPVLPKKTRSSHPITLVLDLDETLVHCSTTQMDSPDLEFNVNFNGVDYLVKGKVRPYYKEFLERASEMFEIVIFTASQKVYADSLLNILDPNRKLIRHRLFRDSCSHIYGNYLKDLSILGRDLSKCVIVDNSPQAFGFHLPNGIPISSWYEDKEDTELLKLLHFLEKIREAEDVRPFVVNEFRMEERIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTQ8</accession>
    <name>A0AAD5TTQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MINDY deubiquitinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001584">
        <property type="protein sequence ID" value="KAJ3202351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTQ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016807">
        <property type="term" value="F:cysteine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007518">
        <property type="entry name" value="MINDY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033979">
        <property type="entry name" value="MINDY_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063">
        <property type="entry name" value="NF-E2 INDUCIBLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04424">
        <property type="entry name" value="MINDY_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MINDY deubiquitinase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="26527" checksum="0678E3AD2542692C" modified="2024-05-29" version="1">MMRCVDPQDEETFRVVARNAKSYDKLTDLIVQGEKNIFEPDQSLGTIDIKGKGKENSSDSVYQDQTNNSQKKIQNSNQILQTDTLIAKNFLEQSSTQLTYFGLTSLMENLQPNSISILFRNNHFQTLFKLENRELLQLVTDLGFLEEPTVCWESLLNVEGDSYFLDSDFREYNKQNFNNSNGGSNNLMNSSNFGINEQLNNLNLNGNLIQSNNDFNFQNQYPPTTTAQSDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTX2</accession>
    <name>A0AAD5TTX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001409">
        <property type="protein sequence ID" value="KAJ3203577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTX2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="196" mass="22895" checksum="D0BB18E8F2119BF2" modified="2024-05-29" version="1" fragment="single">EKEFLKLDIEKKNYCLLNYKNFLKKNEKVLTKINIQNKETISQNLTTAFASNYDNKKNDIVYDIDENFYVNEEEDDINDARWNKSMELDEINFNEESNFEDTNLMEEENSSDAVSVVDVSKLAIVNHNDDGSQVEKEIKIEQVDVIMVSKEDVVTEEEVLQITVKEESKTEVTKEIIEEPEPEEEQDDVGGFSFEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU15</accession>
    <name>A0AAD5TU15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dynactin subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001367">
        <property type="protein sequence ID" value="KAJ3203882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU15"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028133">
        <property type="entry name" value="Dynamitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15346">
        <property type="entry name" value="DYNACTIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04912">
        <property type="entry name" value="Dynamitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3203882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="60293" checksum="CA92335ED3225C66" modified="2024-05-29" version="1" fragment="single">QMSLGHNTNTTTAVSGPLVLDLDEGKDVFETSDTDINQKSNNKYYFDSDEEDDDDSLSDISDINTKIGNNYNQDVTENAEIIKTNLDLTTAQSKFSNSNIDASKADFSDTLKNKKNKNRFYQAKRLPDREEYAILTKNDQTEETSVQKLRRLIFEVQELEEEIKEKEKLNLLKTKNNVDGVEDIPTENIEVHPVTEGDKDLKDFTFKKFLNQVNSLDSELTKISKSIGFNPSLPFEDVELNLKSGGGTLTNNLEAGKSLIHKINNLKNLNMNTTVAENNNVKVDESSKNAVTYELYYTPETAKLISLSKISDLEKRLTNLERLIGTHFLQQIDSSEDSVANLLQTSGSLLGAIDKLDHHLSLLTNPRTLDQVVKKVKGLISEMEQLADLRKKQQFDFNMLEQTNGLKKEKDENSLASIKTREINLEEEKRIDYLFQMLDRLDQVGSVVPQLLGRLHALKSLHTEAALFSESLKLIETEQQKVAENFSNLEDGVQKLTINISENEGKILKNVDILDKRISDLVNRVEKLSSNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUB9</accession>
    <name>A0AAD5TUB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_001167</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001304">
        <property type="protein sequence ID" value="KAJ3204405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUB9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034078">
        <property type="entry name" value="NFX1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360:SF12">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR NF-X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01422">
        <property type="entry name" value="zf-NF-X1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="31"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3204405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="769" mass="87934" checksum="9F3D55C867EFEBD2" modified="2024-05-29" version="1" fragment="single">SFTSTDTGVHISTSDRTKFLAEALQNETIECGICLIIVSDNSKIWNCPTCFGVFHLSCVSQWALETKNEDGIYRCPGCSCPMKKQTEKYFCFCGNVENPPPNRFLIPHSCENICKKKFVTCEHTCSMQCHPGPCNKCPRNGPLQYCFCKRLSFQQRCGEKFPGLTCGEICDNILNCGVHRCREVCHKGSCPLCSIEVTMPCFCGSNTTTKYCGSGIKIKVGNDLLEFYECESICDKKLGCGNHKCPKRCHSGNCQECPTSTKIIKSCCCNKQSIKELNKKRTSCLDPIPSCNSICEKILNCRIHMCSKICHEGECDPCEGEQMISCICQSTSDVYKCSEVIKKLHDNPDWSHKGPCNPCLEAMFEEITCRCSKSKIYPPIPCGTDFQVKCLLPCTNPSYFDCGHEQKSHRCHFGECPPCTYPVTKLCVGGHTLREVSCSNYNTNFSCGKICGKSLPKKNNCEHNFCQELCHDDKCNGDDSQCNKTCDKILANCVHHHRCEKKCGHIDQDDHFGDCKNKFFVYCNCDTLKGLEMECKLLDKFFQVLNFGVGSNSHKVFVDCTNSQFHRCFKTRREQYIKKFLATTLDDSASSVNYQQSVDTLLLIDVPNEINKKEIANFFLRNFTIKKFEFLSEPYEEELNEYLRENERQIKIKGFRDIFIKFGEKLNFSDLTKILNLKKNDLIYFIFFKKKKFKINDINVTEKKKKEETEIDDNFKKESINFKKNNFLPLQNFESEDSVFLEEDKDSKDDTELTIEQEIDISLNNILLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUI5</accession>
    <name>A0AAD5TUI5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methionine aminopeptidase</fullName>
            <ecNumber evidence="10">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">METAP1_1</name>
        <name evidence="12" type="ORF">HK099_000639</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="10">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase M24A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010001159">
        <property type="protein sequence ID" value="KAJ3206015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUI5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000010">
        <property type="entry name" value="Methionine aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF7">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Peptidase M24" evidence="11">
        <location>
            <begin position="64"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3206015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="300" mass="33671" checksum="D49D9171400B0222" modified="2024-05-29" version="1" fragment="single">KTNYNPWENYRFTGDLRPVYPLSENRIVPDDIVKPDYAIDGFPRSEAAVKGSTQIDILNAEEIEKMRKVGKFGREVLEIGKKAAKVGVTTDEIDRIIHEASLERKCYPSPLNYHNFPKSCCTSVNEVICHGIPDMRPLKDGDILNIDVSVYYDGFHSDLNDTILIGNVDEKGKKLVKVTKECLDKAIEACKPGFLYRDLGNIIQKHAKANNFSVVKSYCGHGVNRLFHGPPNVPHYAKNKAVGIMKPGHTFTIEPMINEGGWEDEQWPDHWTAVTADGKRSAQFEQTLLITETGVEILTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUP9</accession>
    <name>A0AAD5TUP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002784</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001954">
        <property type="protein sequence ID" value="KAJ3200187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUP9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3200187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="324" mass="36982" checksum="6F40E24C5753491C" modified="2024-05-29" version="1">MNHLLIPPPLCSEDQQPFNLFSDLQSVFLNNYPTLQLAGNTEQGYYTHDFTLPFHPITSSISLPTSPTSTSSPISLLDAPVFDSNCNQPLHKSLLDTSNIQPSSSTWTSNPTPTQQQAIDDIFFEFFSNPDPTTLIQMKVLPELTPTFPCLPAKTENITAPPVDQSPNKKVDNQVNFSIMDFNSIDDIFNFNPPEQISIDNKEFNQMNKKIKKNVSFVNNNKFKNFEKQKKVLSNSNTTIIPNNHLPNLEALDKNLKNILCTFCFSIFGRKCDRDRHVNSQHEKKVIKTCDVCGKNFNRMDSYLKHQRIEEKRKTSRSKKSFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV12</accession>
    <name>A0AAD5TV12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000497</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001113">
        <property type="protein sequence ID" value="KAJ3206588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV12"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="4">
        <location>
            <begin position="161"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3206588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="472" mass="53897" checksum="2DA3361CE24355FF" modified="2024-05-29" version="1">MNIESTDFAFIQLYNSTLLLNSSFISTVVISLFTALLYYHKKQKRNLIVNMDKVSIDKTLVQMYGTTRPTWTLKNKIVLTLLKKVLAVPQTGADVVAAKKKMAKGLGININFMPKGVVLETINVKRLEEVNERVGLKYSGEIKADWIEVQPRKKTKDETIVLYLHGGGYVMGSRHTHRNITGKISKLFQASVLVPDYGLAPEEPFPIGIYDAVSSYFYLLEQYRPEQIFVMGDSAGGGLSLGMMLWLRDHPKYPMPGGVIGLSPYVDLYSTHPSFILNRPFDYLTALIGNEFTERDKKLTKERNFMYCENNEDAHHHYASPIFYRHKKDDFEALPPILIQYGDSELLRDECITLYSKTFPTAKVRLEGYEDQIHVFQMLPFNSLSGVAMTQVLDFITEVKNLKNLNKLHEFKRTSVEFLNGGSKKVLNNPYSIVENGNKVIEELRAKNLLIHFDKIRKSLPDDVFIGKPFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVN8</accession>
    <name>A0AAD5TVN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001017">
        <property type="protein sequence ID" value="KAJ3208030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVN8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="90"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="27155" checksum="2952658FCF4116D9" modified="2024-05-29" version="1">MSSNLINSIDDLLTNLDLTINELNQSNNNRHHNNLQIDPTQKKIYVQQPQRVESLPHIFVNSPSEPLIYKPPKDDTFREISGLSDAFGGWIDQYLVLANSTLYIFTSDNYQEKYEDSYTINDTTTIETSTKYPGVIEFKTDIFQASRSERVFLGNIRLEFQCKDEHETNVWFDCFTEAIEEAKKGRKPSIFSPNAFSSSNKRDTSKSNDSAVSFNSPPASPAIKSEKVFAMPKNQRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVZ3</accession>
    <name>A0AAD5TVZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Neutral amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AVT3_4</name>
        <name evidence="9" type="ORF">HK099_008255</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000892">
        <property type="protein sequence ID" value="KAJ3210417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVZ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="519"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="606"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="300"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3210417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="627" mass="69471" checksum="AF36C84A51FA50EA" modified="2024-05-29" version="1" fragment="single">MNNQNDKTTVNTKNIPTRTIGATKTKNKSTEDFANNRNNSNNGISMKRGVSTPIQNSNSSSLSRSIPRNDLMPSSLARSIPRSIPVRMATPTSFKSSNAVSFSTPNSSFQSNKSSFINRYGSMSQSSQQQQDEAQAQENAEFLNLIKEHLVTENSDGDPVFGSVSHSLLGGAITRDIYLYSEKRSQPSIGGKRRNSAPDISAPISVENASNETEDVITASTLRQPGGFRRHFIQNRAQREGQKPPNFLSANFIDFLVLYGFYGGDIEPEYSDESEDEVFLDRENQPLISSTRRSSVEIKGTSPGKAFFMVIKAFIGTGVLFLPRAFLNGGLIFSIVTLVILAWLTLHCMLLLVEVSKKQNGLSMGELAGVLYGSNMRQLVLWSIAISQMGFSSVYYIFIGKNLKDLLTVMSNCRLILPDWVFVLLQVSLYIPLSWVRNIKHFSITSLIGDVFILMGLAYILYYDIFTLVKQGGAAKNLVYFNQESFPLFIGSAMFAFEGICLMLPIGDSMKEPEKFPKVLSSSMLSVSVTFILVGSLGYITFGSNTDTIVFLNVESSQLLTSLELLYVAAIMLTFPLCVYPAVRITENFFFGTHLHRTNTLAWSKNLYRAGLVSLLGFISWVASDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW61</accession>
    <name>A0AAD5TW61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Importin-alpha export receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CSE1</name>
        <name evidence="8" type="ORF">HK099_008393</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000915">
        <property type="protein sequence ID" value="KAJ3209983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW61"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF8">
        <property type="entry name" value="EXPORTIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="25"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3209983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="38244" checksum="5BCFDD6B871614F5" modified="2024-05-29" version="1">MTVLPMNNLQLLLFQTINPTTSKHATQQLASLEKDPTFTLNLLNLINDANDSNLQLTGAIYLKNFMKKYYHEENIIPNETKNLVKSNIVELCLKLNQQVQFQLYDVVNIIADCDFPDQWGDLIPALVNKFEMNSPSRANVSALQIVHGVISRWKGEYKSDHLFSQLKLVLSQFCVPYLELFKRTDMALDQLLLDPNQHKEKLSLVLETILLLLNIHLDFIGHDLPEFFEDNASTFFQLFLKYLKLDLKLNTENHDEPGFNEKIKTCICEIVDVFAKRYENEFEMLPTFVENIWNLLVTTGLESKNDLVCAAVNYFDIKLFLSWLAKQLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWF4</accession>
    <name>A0AAD5TWF4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001376">
        <property type="protein sequence ID" value="KAJ3203818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWF4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="131" mass="15305" checksum="19E888E06914A11F" modified="2024-05-29" version="1" fragment="single">MYLLHSEAPKTLNQISTEIFNAHASEIVDSKKFMNKDDFLKAIKPKDLELNLNFDQTLNSILFKLVDVNKNGLIDLDQFIDFEKNLLLKPDNENKILFKILDEKNLGRLNVKELKNKLQQYQHKDAAKIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWN2</accession>
    <name>A0AAD5TWN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000808">
        <property type="protein sequence ID" value="KAJ3211883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWN2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017943">
        <property type="entry name" value="Bactericidal_perm-incr_a/b_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55394">
        <property type="entry name" value="Bactericidal permeability-increasing protein, BPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041925645" evidence="1">
        <location>
            <begin position="21"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="317" mass="34965" checksum="DA856D6059B63EFB" modified="2024-05-29" version="1">MVNFKVFLLTLLSTVLLINALPGGKKNDPTPVPSTDDSIILAPLPWPFKKLLTFEIDAPAIVLPILKPITSGTAKSDPISDTPLNLDFPTAVKVNLQQPLFSTIQPMVNDIFATYLKNLTISNLPDVKVHVAVVGDRLFKVSNFKVLELDLDQKQTHINIEDGFVSINIDDFHLKISTDYAVTKVNGEVSFSGSSTIETTISVIGKLVLHQTTNGQMGFFLNDLQVPFHKLKINVSNNILNWILNLVNSIFNSLTRFILSHFVEDIVEDDIIPGFEDLINKQINLGSTSQFRTVSIGFPTISKTDGINIALGLEVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX54</accession>
    <name>A0AAD5TX54_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">LCB1</name>
        <name evidence="13" type="ORF">HK099_006837</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000614">
        <property type="protein sequence ID" value="KAJ3214528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX54"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF2">
        <property type="entry name" value="SERINE PALMITOYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="12">
        <location>
            <begin position="138"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3214528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="520" mass="58564" checksum="DD3DC715393247B1" modified="2024-05-29" version="1">MNKLINEDTAVILTQSLKNSFNLTLIEANKYIVKIPGAKIFLKYLKSSYQNDPYRVFFELALFFFLIWYFNHEKKKLTDKQKVVLTEKEIDELCQEWEPEPLVPDLTEFQKEELRKTIVISGQTSTKVKIQGDAKEKFNLASFDFLSILNRESTKEKTIEALRKYGVGTCGPRGFYGTIDVHLELEQKLAKFVKTDGAAIYSQNFSTVSSAIPAFAKRGDTIVADDGSNLAIQVGNSISRSNLHLFKHNDMKDLERVLEDLKKKEQKKKSKTITRKFIVVEGLYMNSGDIAPLPDLVRLKKKYKCRLIVEESLSFGVLGKTGAGLAEHFNLPAQEVDIMVGSLTNSIGSSGGFVAGSKEVCEQQVLSGQAYTFSASLPAMLTVGALEALKILELEGEKLLVDLKENIKIFWDTFTNKKFNLESKVEIFGGLKDPNVFSPVIFFRLKKVSKNRESDEKVLQEICDLSLKDGVLVTRVSFCQKQEKTLLPPTVRVVLCAGLSRKESEKCAYILREAILKNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXB0</accession>
    <name>A0AAD5TXB0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Myblike DNAbinding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SNAPC4_3</name>
        <name evidence="9" type="ORF">HK099_007117</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000664">
        <property type="protein sequence ID" value="KAJ3213939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXB0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="386"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="387"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="432"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="490"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="490"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="493"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3213939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="534" mass="60987" checksum="8A0B885AC64CBA5A" modified="2024-05-29" version="1" fragment="single">MASFTTIQQTCSSSNDNLIIPKLTTASQLPIENVNKTLDHQSSHFVTVFHDENLNPVVDEYDVFNEFSLERSHELQDSEMIFLSQLKGATSSTGLDSKQPITKNTPIIPRITTPTFTSHTDQSKPHQYQYYIQEKNQDLANSASHSFSNIKLEANNLDYLTDSISDNFSSPSSSILNLNSPIIDINSKLTNLTWGNPPIDRFVDFNALQQQSQVPLQQQQQHLSLDVSGNNHGLLYHQQLENEREFFKQFFENEDTSGNNNQYDNRNNSNVLLSPLQQQHLDIPDQQNLRSVLFPVPSSSIKSPYYFPGSQQQQPNVLTNVLYENSQFGKDSSSCDVIQTQSPIKLELSPTTTILTPPTSPPDQTFLSSSVLSQDINSNNKQTFYRKWTKEEDNLLLMGVEEYGSNGNWNKIAENLDRTAMQCSTRYFGALNTSIQKGKWTLEEDKILLEEIQKRLKVHQLKDLNWLEISRSIYGRTSIQCMARYQEALDPTVKKGRWSEEEDALLKKGLSEYGKRWVKIAEIVHGRTQRQCRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXI5</accession>
    <name>A0AAD5TXI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000574">
        <property type="protein sequence ID" value="KAJ3215029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXI5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029152">
        <property type="entry name" value="LKAAEAR1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15478">
        <property type="entry name" value="LKAAEAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="432" mass="49626" checksum="4DBC0A6CC12943B7" modified="2024-05-29" version="1">MSAVHVEPLASLCRTDSSLTGGPTPILLSERFKRTLHNKQIFSNGRWRERCNTQISDDISNSNLNNQNNADLTQKTSDSDLQNSNSSHLQKHNDFSLKADLSRLPSIPNSIEKKNSHSSNKNYTHLQKNVRQKYSNSVSANVNAPRLSVSINLDSTLASSSNYSAEVNQTQSSNTGNSQNQNQNTSNTNNMIKTEIVEEKFPETDREQNSFDDNLLEGCGDEEFKYQPFQLNPKSSFNPVNLTKKTLKNMPRLIKSKYMAYEVPNPALLLKIERSELRSRIIIKKEQEEIKNAIRDYKKMMEKKKIGYDDDLVALQGARKARERMHMRYKAQMWMKELELQYLVEGQSNSIDAIRLKENLPLHKPKLLFSDSQETPSIYTSNFEKKKKKDIKNSRNSKYQNTNTKSFQKEIDFNGTENFHSVRVSSKKSKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYJ4</accession>
    <name>A0AAD5TYJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MCA1_3</name>
        <name evidence="4" type="ORF">HK099_005857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000477">
        <property type="protein sequence ID" value="KAJ3216455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYJ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="3">
        <location>
            <begin position="245"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="520" mass="56717" checksum="C0B84645C8663D96" modified="2024-05-29" version="1">MSKPTSKFEPVHILTPIKLSNQVQTNPKKWDPLTNKKESPVIPEAPTKVIPEKVIERSAAPPSLPQKTIVATQQAIKSSVLENNDPSSRFGFSNSFFNQTFETSTTITKNLVKSDNDKSNTTISSSSTTTTTTKITKSKLVSTNSTSTFSGKSNVAKDTNTLKIEEIFDDLNLKHPALSENKKQPVLNNFSTKATTLSQNTSVKVAPSVVVPPPPPPHKSSTSGMQPPKMNTTSASTANFLTGGKKALLIGINYTGQKNPLSGCQNDVKNLKTYLNLNEKDLMTLTDNHSTAHLKPTKKNILMGIDWLKKDAKIGDQLIFHFSGHGGQIKCTEDEYEEDGFDEVIFPLDYEAAGCIVDNDLYKVLVKDLPTGVHLTAIFDSCHSGSILDLPYEYNLEQKRFTAINSTKAKKFDSGWSMNKKDNIGSHQEKAPSSVNLGNVICLSGCKDSQTCSDVKYLGTAGKEATGAMSNALLTTLKANPNQSYSEMLNSLKVILEGKFNQLPQLSCSSPIDVNKKFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYK4</accession>
    <name>A0AAD5TYK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CPR6</name>
        <name evidence="6" type="ORF">HK099_005835</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000474">
        <property type="protein sequence ID" value="KAJ3216521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000025">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase CYP19-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="10"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="45413" checksum="8BCE76793E58D125" modified="2024-05-29" version="1">MTVEENTFCFFEIKIGQQNLGKVVFELYSKYLPKTTENFLELCKGEKVDADGTRLTYKNSIFHRVIKGFMAQGGDFTKGDGTGGKSIYGDRFDDEDFMFKHDVPGLLSMANAGPNTNGSQFFITTVATPHLNGKHVVFGKVVHGMNIVRKIENTKVATGDKPVSDCVIIDCGELPSNWKDLFPQPEDGDLYNDYPEDHPVKNKESGDHDPIEMLEIALKIKNYGTELFKKGEYEKAAEKYRKAVRYLDAIHPVPEDLDVITEEQKMEYFSIRVSSQLNEAMSHLKVNNFAEAKVAASKVIELSDRLKLNLKKKMEKKENGNADIKITDFTLKPVDLCKAHFRRGQAYLKSGGPEQALTDFLVCESLDSEDKFVKREILLSKNLIKEKREREKKAYSQMFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYP5</accession>
    <name>A0AAD5TYP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Association with the SNF1 complex (ASC) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007679</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000767">
        <property type="protein sequence ID" value="KAJ3212697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYP5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000562">
        <property type="entry name" value="Snf1 kinase complex beta-subunit Gal83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006828">
        <property type="entry name" value="ASC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037256">
        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="5">
        <location>
            <begin position="555"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="290"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3212697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="660" mass="75284" checksum="D7E66B41E12EA13E" modified="2024-05-29" version="1">MNSTVDTLENSENLESIFQWFYDQKIYKLVEQRVQFKEELTIYHRFNGLRIGKKIIDISSEFNEKTRQFSYIVKVVAEWKIDIIENGNLVTKTKVETLEAKILPNLVTESQKSESKIDGEINNWLFYEFTDDSGIIVKGIDGDPNTENLKYIIFPSDVKLLLSEGASYVLLRLSALYSRLGRTRFMTTGPKSLVKGNIFFDQVVDTSDEADCKTLEEKPKKKTNIGSFVQFSLIAFNNSKIRDVKNLFDFNFISNLEFDCFLNEHGKILKMEFKNSNYWCKKEYERGVMGSQQSTIDEKRRKSLSNSNKHLNKNGFSSNHQIGGVHQRNSNSTSNLYQPNPLEHTSAANNNANSSTFSQSIAIPISNQFKQNSSSVSASSVPRNSSYKLIKLTHRHDLLTSSSLHNQVINFKSKINFPSEQERNLYKNSSKIKHDFGPTIAPLTSKKDLEKKKKIIPIILTWTQGGENVNITGTFNNWKQKIKMKKSAQDFSTIIDLEPGTHRIKFIVDDEWKCSDDLPIATDSDGNLVNLIFISDETGNGLGDGFDNCESGEFPQEPEVEIEYNNEIPAYLLKSDQERNYEEDLNLNQAKTDLVEDKINQLPTEPPPLLPKYCEKVLLNTVQESKLDLLKLPIPNHVTLNHLYACSIKDGVMALACTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYW6</accession>
    <name>A0AAD5TYW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000730">
        <property type="protein sequence ID" value="KAJ3213255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYW6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="166" mass="18780" checksum="4B8607F4C649A52B" modified="2024-05-29" version="1" fragment="single">FSTDTENQIRNEIKPKKAVDNDCEKVLLVSVVVCTVRNFATTIVNSINLDLTKGNGLILMVFVQFISVPMDIWLPFFLIKNVTKTIKTNEAATKDLQDFAPFYDYLGQNVEEVVDNEDFTKCIKNDKKKSSIDNKKALEKHKSNLFENVVTAEQLCTQTVTHTSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ32</accession>
    <name>A0AAD5TZ32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bacteriophage T5 Orf172 DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000706">
        <property type="protein sequence ID" value="KAJ3213476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ32"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053006">
        <property type="entry name" value="Meiosis_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28094:SF1">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 113 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage T5 Orf172 DNA-binding" evidence="1">
        <location>
            <begin position="41"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="159" mass="19095" checksum="F5EF000B4F2F22E1" modified="2024-05-29" version="1">MDEFPGKQIKFPFYSDVKLETGKKIFKRLLEGVSIHDKKGWIYSFYKKIDGTWQEQSLKIGRTDNSVEKRLRQWTNQCGEELKIKKSWETKWNHLTETLVHLELKDRGLWLGNINGGGKCNYEIQKEWFSASVFHEIDNVVSYWVRYVDALERYYYQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ35</accession>
    <name>A0AAD5TZ35_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005709</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000459">
        <property type="protein sequence ID" value="KAJ3216806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ35"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3216806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="369" mass="43579" checksum="3B6BCC04EE63338A" modified="2024-05-29" version="1">MKRNFSTTKLILENYWDSLRRTDPKNKIKKIDISKYQHLNLDQLIKTETVPRTTKVSSRNFIHNSLYNHNYGYFNKKAPQTEIDFSKIRDNYDFLNYTSNLYKQIDNTELQNSEARQIWHTPTELFRPWYGYALANYILTNYTLDKKGAKYLHIFEVGGGNGTLMLNILDFIRSNNFEIYQNMKYTIIEISDLLLLKQKEIKTHEGRFQIIKKSIFDWETEFNDPCFFISMEVIDNFSHDVVRYDSDTMAPLQEMVLIDEDGDFEVGFEEVTDPLLKRYLSIREETGYVSPILRGFHVKRFLKSFLPFSSNMTQPEFLPTMCLQFFEKLNKYFPKHRLILSDFSSLPDAVNGVDGPVVQTRYNGGIFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ62</accession>
    <name>A0AAD5TZ62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000668">
        <property type="protein sequence ID" value="KAJ3213880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ62"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="167" mass="17838" checksum="C2E8338994011368" modified="2024-05-29" version="1">MSSSILSTTTSFSLSKKATSTVSKFLTSTNNSPVTTSHLTASNAVNENTLSAALTATIKTTLSIVTGTITTTIIDPLNNPVIGGTKSTVSNSNLIGTNTPDPQIEINRLALLEKEKANTKAASMLTWFIVLGIILILVILIAVFYFRNRKRILLRTKSVSAHSMTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZE6</accession>
    <name>A0AAD5TZE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000423">
        <property type="protein sequence ID" value="KAJ3217509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZE6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="48"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="405" mass="46798" checksum="69D4085233D9814E" modified="2024-05-29" version="1">MSMFHKRAANNLLDLCLKNGGVYIKLGQHIASLQYLLPEEYTDTFRVLQDECTPSSMQEVENVFKSDAQLNMDDFFSQFNPDPIGVASLAQVHHAVLKNGQEVAVKIQHSSLDWFSKVDINTTVNLVFLVKKLFPDFEFTWLAEEIRESLPKELDFRMEAANCLKTEKFFEGDERFKVPAIYWSDRRILIMEYIKGGKINNPKFLSKHNINPESVSKTLHDMFFSMIFNVDDIQIHCDPHPGNIFVRPVKPKKHNILYRVLNYFSSTKANFQNFELVLLDHGLYRTLSKELKLNYAKLWNSILVGNDQLILENSLSLFKNSKSEMKKSRDGFDYHRLFASMLTGRSWDVISNKKLSGKRQKIEVKRVSEKIKSVGFFLAVSEVLAALPREILLLLKTNDLLRSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZI5</accession>
    <name>A0AAD5TZI5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005998</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000495">
        <property type="protein sequence ID" value="KAJ3216133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872:SF2">
        <property type="entry name" value="INHIBITOR OF BRUTON TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="171"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="236"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="289"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="345"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="599"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="736"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1005"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1005"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1023"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1281" mass="144990" checksum="7720F3842D8EA635" modified="2024-05-29" version="1" fragment="single">MSKAFTTSPNSTNFNATSANMSLFNSVRKNDISNIKAILAKHSQKINLNERNEDGLSLLHLAINQNNFDIVELLISYPKLNINITNLESGWTPLHLSLYNGQLKLSLKILNFRKDCDLYIRDNEGITCLELLNSTILSLKNVQPFKKKRRTEDDSDEEGDSEEGEVENNHYSVFAWGNNSNYILGFDNADDRSFPEMVTYKDLNVSNFSLKNLELFQPKIKDIQMSKYHTVCFTTDSVFTHGFGRAGRLGLGNQETSFKPKMIEKDFFKLQVVMVALGPDHTIAVDANGTAYTWGTNRFGQLGYVTDCGLDCQLTPREVGGSLKKVKIKLAAASKFHSVVVSSTGQIYSWGTNNGQLGLDYSAEVVQIYPKKVTSFTHIEILHIAATNTSTAVLVDNRCGEIFVFSNFETKKVSFPWNSPLKNLKHNHKPVRFNEKSNLIKLVSGVQHYAVLTSTGEVYMWSPSKDNHTVFNMEPQKVWSLRKSVFLACSDISIAIDNSLLVSTISGHVFYGVKRANVKLSKYEKNTEVYYKFTKLPYLQNIKKICSSPSGGFAAIREDTRPKYLFSKFQSLKQELEACYLLKKEEARVFNFASGTPCFDVLFETKKSKFGADRVILAAHSNYFYDLFLNNRDFTVGEEILLPDNLKLKCLKQKSHTLYHITIPESISEDFPFVLDIIYGVKVDVNSIGLSSRLGFKKLLIHFNVQQIQSLLASTVLFPSNYFQVLLADKKFTRLADVKIKLSDGYVVAHQVLLAARCDFFKCMFIGDKWRLTRDDAMDLVEINLTHVKTEVFEIVLKFLYNDGDVELFDDVKKNFFIEFISFVVEVLAIADELMLGKLKEICGKILVSCLELSNVLQILEISENYSLAPLKSSVLEFICQNLETLIETKMLSSLEECLIDDIEDHLILLQNLKNPKTRGKDGFYENLRLKVAEADEKRKIERRRRYEFTESSEGSCQCKFGNEKEENIFVMDIEDPVKDSSCNLSAIINTQEQKPNQHTLEKVSAISSSGSKISFDKDSPKKNKKHSKPKNWKKLDLYPAEVDLSKISPPSTATVEKDIRHIPSILSSSPTAAKTWNYKPESSKNSLKNIMENESKSVSPPSLSHMSYATSSTIKVQKNNASPSFTKNVSALSLSKSPAKSTKEKPFTLQFPSKTANVSPTTHSIGKVLDSPVSPIPVKFANKLSQKEKKKHFMLEKEKFSVGSKSPKEEKKLTPSWGNMAKLKNEGANVKFSDLMNEEKVNLKLSLREIQDEELDRKKKSIVVKKSFKDIQIEEEFIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U017</accession>
    <name>A0AAD5U017_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Kinesin-like protein kif27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KIF27_4</name>
        <name evidence="12" type="ORF">HK099_007417</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000717">
        <property type="protein sequence ID" value="KAJ3213378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U017"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.630:FF:000001">
        <property type="entry name" value="Cyclic nucleotide-gated channel alpha 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF19">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="355"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="526"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="596"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="657"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="469"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3213378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="680" mass="76600" checksum="CA0F75FF1EE87756" modified="2024-05-29" version="1">MKIEKQLPPGPTGWLEILSDFYLIPEGAFLGKWNRIMVAVAVLSHVLITFQASFHHYWISSFAAGYVFDVFFLVDIFFKMHTAYLQGGFWVVFPREMTIRYLASSEFKFDVISNFPYDLFGLIGLITPGVDMMTLLSLTRLPKVIRTARILIYFRAQEQKLHASFSIQIIKFLTYLIVITHTIACVWYTLACPGGEFECIENSWVQIIGGGMRHNPLNTPTTLYITCLYWTIATMTTTGYGDIRATNDVERVFAFLTMTTGTFFYGYVSGTIASTLSNMDSRRVSYQQKMDAVKQYMNNRDMDFEMQQRVIDYYDYVWERNRGIDVKNLFEDMPITFKSEVALSLNNQIIDKASIFHNCSIGFRRRIAISMRLYLFTANEFVVHKGDLGLEMYFITQGRIDIYAFDDVKRAAASLIEGGHFGEYGVVLGHRHENSAKAICNTDIYVLTREDLSSAFMAYPDDKEKVQKATQDQLKRAQETRKGRALDTDDDLLEEEFGAVESRDAGAAQVADNFLILDRGSKSNRGSMSNINLYSSNSHRKSFSQAGMSNRRESLQPGGKSKKSPPVKEGADDGQCILSSAKLKEVVSMEEGGVLSKANSHSDQQPLNKSLSSSSNHVEQNKSSSALALLSSNNKKSTQAGFLVATSHNQIPAINVCKTSSKQLHHSKSSINDKKENESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U085</accession>
    <name>A0AAD5U085_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromodomain-helicase-DNA-binding protein 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CHD1L_2</name>
        <name evidence="7" type="ORF">HK099_006481</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000560">
        <property type="protein sequence ID" value="KAJ3215196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U085"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17919">
        <property type="entry name" value="DEXHc_Snf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031053">
        <property type="entry name" value="ALC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47157">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47157:SF1">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="752"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="1047"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="220"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="349"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1167" mass="136269" checksum="43142F94A6763584" modified="2024-05-29" version="1">MATVLEQLPSFAKEQPSLPPIGLSNSIPTGDDPANIGSNFTKLTNVEAQRIMSVLNEIQKKVLIIGLLPDYQDKRINTVFFGDILQAVVEQGKFEQKYKSLLEHKELLESKKEPIEAVQVINIMLKIKNNTNAFYFTIKTEIRETSRQLKNSTRSLYRQFLQNPASISKLRYLRNNKSTSISRFEQLLQEVRTLVYDRLRTTVEEENNKQDQLSVIIAKEQKTSNEVRALQEELEKARRERSNEISKRNEVIRKLKEDLRQIKHEAEETTKRLETKSKQKENNDVQKFQDKETTLCNEIESLKLQLSVELKKNREEEESLRKKKFKIESEVENWIHKFDTEMEEKQTELEDITALFTERKKELDELQLQYNILHVEYEKIIEERKIADEKRKIEEAILKKQSAACVIIQSTWRGYKVRKDLKKKNKEVNSTMFNNTLNFSHSKITKIENLPTSLQSFKCHYNRITKIENLPTNLQSFICHYNRISKIENLSSFLMDFNCNHNHITKIAHLPDLLQEFSCEANLITIIENLPTSLLIFNCRRNKIPKIENLPGYLQEFNCAYNFIILIENLPSSLLKFQCDNNQITKIKNLPSTLKEFICHGNQITKIENLPTSLKIFECSNNQISKIENISPNLQYFNCCVNRITKIENLPSSLLVIFCYYNQISKVENLPLTLRQLHSNYNPITVIENLPMGLINFEFDEEHVEFVIKYHTGEYANSLKIKQLHLISTQPQQLSAEVVLRFYQLQALQWMINLYDNNLSGILADEMGLGKTIQAISFLTYLKFDLKIPNVQFLVVSPLSVLQNWSEEITKFSSGLNLFSYHGSKLERIELRELIQNKLVEFDVLLTTYETVINDIEFFEDKSIFNWTFLIVDEAHRLKNRESLLFKSLLNLNIKHQLLLTGTPIMNNLMELHSLLYFANPLIFDVDPKEFSSWFTTGDAVKGENLSNLRSILKIFMLRREKDQVLSLPSVKETVIYTNLSSLQKKIYKGILMKDLSVFNEKKKLKLMNVLMQLRKCVNHPYLFPGVEPEPFICGEHLVDVSSKLQVLDRLLNYFKSKKRKILIFSQMTQMLDILQDYLTFRRYSYERLDGSVRGEERFLAIKNFQEKKNDTFVFLLSTRAGGVGVNLTEASCVIFFDSDFNPQMDAQAQARAHRIGQLNEVLVIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0P4</accession>
    <name>A0AAD5U0P4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">R3H-associated N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000280">
        <property type="protein sequence ID" value="KAJ3220690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0P4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="37882" checksum="75D53A7F4563DBCD" modified="2024-05-29" version="1">MVEISILSSDDESTSQNLFMIPIIINNPLIKHNAEESTVRFGNKNLHTTREIKNLAKAKLSNKERKRLTNDTFGKLEFDFNDLDEIDLISPGFYLEGFKFSKVKIDSTFFKQNYTEMKNQQNNGITSKRNLNGYLSLNRSDKNLIKNLKKKKTSLANLKNFIFDFQNLVLNYISNMEKKVLELSNRRELKSSTFNQKTANNTFGEEVIFVDAYEKEGDSASVNSDDFILIKKEDLEWVVENFKMEYFEVKINNNFYRLVAHLMCRFYKLDSFTTTNSLRNNHSDDEFSLTFFIKESCLDSLLHFFNNFNQSVKFNSFTNFLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0W8</accession>
    <name>A0AAD5U0W8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000374">
        <property type="protein sequence ID" value="KAJ3218564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0W8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="717" mass="82056" checksum="66023FCBB4C72C92" modified="2024-05-29" version="1">MLIGENSKAISHWVDKLNSFQLREQVNGDIYGFFTKKMKITPTAVYYLDFACCITLHVISKIRIHDNITWSGDLNYRHMKCFEKKKEIASNDISFEAFILEVTKFALNVLDHLNKKNYKHQEHSLDLLNRTCIILATLCTNGILDPSFHILSEEILLYTHKFHGASEEKFSDFQLRLEKILSLFFTTDNSDANADKSSVNFNRELKKINLGNERAFEFVFAEIFGSLTHESQKEELIPDFNLLKTVQSCYKINMEVPIEENTIIGVEECANYLLSEAITDAEKKISNEWFRASCIKEDYLEMQKIGIKNFVAKKQEENPNFVLQPRVVASCLKSWIRSIETGSDVIKVKKVVHVQKLLEANPTKLRLLRSIGKVARFIFNNSVVKIKPPDFATVLSVGKVDVITDGTLFKRNYLTEVKEKRLKWNKAFDLTTSFEKLSKKCVLRLTKEQIHFIIKKQDVHSGVQVFAQLDPSLIIDDFILESNNNNEIYLEFFIEHFERALKSCCNSEETNLRLTKINNLPCLLFTINENNRSGHQIKLTQQVPVRVLSPVQVLDLQEPEIPEANVLITLPPLHALKYIERMKSVSNFITLSANMKGELKIKAETDMVKIETFFDNLINPDLGMLLQTSSVKYSFVFVDPTQIDIRSHPSSKREAEEFAEARIDIKDLIKFVASGSVNPTQVVACIVEGHCLNVFVFIGSGENPAGIISYFIPVKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U100</accession>
    <name>A0AAD5U100_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MEP5_2</name>
        <name evidence="13" type="ORF">HK099_004224</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000293">
        <property type="protein sequence ID" value="KAJ3220534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U100"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041775593" description="Extracellular metalloproteinase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3220534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="701" mass="77196" checksum="DFD41DF6EC4EA778" modified="2024-05-29" version="1">MRVVHHLISLSSLCLLYASIALKYPTSLENNFFFPKPTYQVNENQVNSDTITPSTFTSFTATDSNSNTAISNDQKIVICSAYLSEQLSIKQKNILCSTVVETSTDVSNVHCSPLIKNLEVVNAAANCNINRVGVVVGFGSSWVPENLPVEKEKKDSISLVEAFKYFADIMNIKYKTSDLDIKEINGENTLPYEFGVVKISKKLYMTAESLNKVFALSVPTENDHFNVYISTSSKEILGVLSLSVYERGGEWKKPNSLEKRDFKYNVVGLPSSDISKGRVILTDPADSVASPKGWHFAADETTTNGNNIYARDLSQGFERKPVATNKNFDFPIDLTKDPASYWEASVVNAFYVGNVVHDISFKYGFDEQSGNFQYSNFGTFGKGGDVVVINAQSSVPYGNPPSTTNNANFVTPPDGSYPTMNLYIFSLTNPKRDSDLDNGVVIHEYMHGITNRLTGGPKTSNCLTSSESGGMGEGWSDMLAMILLAKSTDTRETNYVMGSYVVNNKNGIRSYPYSTNLKINPLLRSSAPAGTEVHALGEIWASMLLEVYWNMVDKSGFTSRLLDDVNSGKGNSDFLQLLIDALKLQPCNPTFINARDAILLADTNRGSKYKCLIWKGFAKRGLGYRYAGKSDDFTLPAECSTVTPPPPPPTCKHHKCVVGTFLEKTCDSCVEKVCKETSSCCTKSWAKKCVKKVKSLCNITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1C1</accession>
    <name>A0AAD5U1C1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007406</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000713">
        <property type="protein sequence ID" value="KAJ3213416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1C1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="3">
        <location>
            <begin position="143"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="76523" checksum="8C2C6337EED3E69B" modified="2024-05-29" version="1">MQTFIFPQPVPQVPPISKQQQQIWQSQTTTDGKTFYFNTQTRQSQWNKPEELMTDLEKDLNSLDWKELKTKDGREKVYYHNKKTNETTWKVPDVWKNVLEKHRLIEEKRATMNTPLSAIPLFRPVVNPVFHVAKPVVEEFETKEEAEEAFKNLLSSVVFSSTATWEEVLPHIVTHPHYRSALKTLEERKRFFQNFQNARIAKEEEERKIKMQNNKAEFQKVMDRRKDITPDTRWKHIKVSFKHEPIMRILTESEAETLFEECLIDLRKKLRDEARAVRRQNVDKLNKLLHNFHQNNQINHMTSWREAKSLIKNSRQYLDDKKFQEFDMIDMLMQYEDFIKILQSRYNSKKFIERSEVKRLERINREEFISVLKRLQNDGLIYCRTKWKEIFSYIKEEESFRSMLGQPGSTPLDLFRDIVIEMEDLYLRDRSVMEEMIKERGFPIKVNTEFREFLDYFSDEQKSFLNKHSLELFYDEMMEEAVYFEKLEARKKEKKQKKKVEAFKHYLKKLEPPILIDSKWEDIRPRVANSEEYVALEEDTRALTFEKYLVRLAEKAERNRNMKSDEEAEEKRRRSTKKKRARRYSSEDEFGEVKEKRRRNQNDLEETGNGSKSRRDQRYKKTDSEEEGEVKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1J4</accession>
    <name>A0AAD5U1J4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000341">
        <property type="protein sequence ID" value="KAJ3219393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1J4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006886">
        <property type="entry name" value="RNA_pol_III_Rpc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="234" mass="26524" checksum="335AB5860F2DC51B" modified="2024-05-29" version="1">MLSEIAFLVKGVKRGWKLKWDPDLDFIERYPEVVANQTRIVLEFGKNCRDQMTGVAGKATLNVQKKEKLLPLSAGSSVLEQQKVTSTVLTSAPSGKTVHEQTKNYIRVLMKEKGVASFKYLENCIESRKKDSKLENNLLNVKPVADEFVKTVIGEACMEVQGSLVLKTLENAVVDEFRKPILQLFQKKKTLKKNEIVGHCENIVKKEFPKNLYREILKEFAVSKGPVWSLKEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Q4</accession>
    <name>A0AAD5U1Q4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NrS-1 polymerase-like helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000656">
        <property type="protein sequence ID" value="KAJ3214031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Q4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045455">
        <property type="entry name" value="NrS-1_pol-like_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19263">
        <property type="entry name" value="DUF5906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NrS-1 polymerase-like helicase" evidence="1">
        <location>
            <begin position="178"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="375" mass="44018" checksum="84BECEDBE36A3DDA" modified="2024-05-29" version="1">MLRRKVTNVRNLLLKTARLSKLKKTNDGILYKQIEGVSYGYEKYKKLFSWMQDVLMNNRDAASHQNIMDRVKKDLLQNDYEELSLLHFNNDYIGFKDGVFNLVECEFTKKEEVEKDLVCRKYFDMNFEEANEKKSVYFDKIFTDQFEDEGVINFTKMMIGRSCFEVGRFDKWECMLSIVGKAATGKSVIINLVVAMNEKRVGAISDGFEKKFGLSQIANENAVVADELPADIERSVPAKKLTELIRGDIIQMPVKYHQDLIEKWKVPMIFAAMDFPQYKSSIVANYIIITEFAKEVQQINCTLKKMVENELPIIMINCCKMYKEYREKFKDVNVWKFCPYYFVEMRHKFLLAMGFEYATEGCIIEKKIVREKEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U237</accession>
    <name>A0AAD5U237_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000337">
        <property type="protein sequence ID" value="KAJ3219510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U237"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="156"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="241"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="376"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="434" mass="51468" checksum="F1F8359B5CD0C9EC" modified="2024-05-29" version="1">MQPIFADKLKKQLKVLESQHIKDYNQIQLLEEAVNFHKDNYNKLNIEKLTLSDTLEASKAEYSYFTEQLNLAKNEAEKLQKKLDYKSKECITLANELKSLKKENENEKKFFESEHQKEVGELKLKLNIWIKEEVFRNSESEKKIQALQQDYEFKYKNSENSKIFELENLKEKLKEKEDENKATMIKVNKSFELLEEKTSLIVQDLELEIAHLKSKCESETVFRLERERLFEEELMVKEAEKQHYLSEMETLKTKLKLTEEQLEVNNVRVVDLNEKFDLLKTENEIKIKSLEKTCSSLESEKKILEQKFDKMIKRDDLKIQKQQSIALNLKEKCEILINTNKLLLNEKLQLGLKLKMETAMNSNEVTKYKYKYCTLNNNLLSLNSELKEESSKLRNNNLTLQQRLSFNNKLLNDLKDLKKDCLSLKEQKKLIKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U260</accession>
    <name>A0AAD5U260_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000377">
        <property type="protein sequence ID" value="KAJ3218519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U260"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042154043" evidence="1">
        <location>
            <begin position="17"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="343" mass="37795" checksum="B10B03AB0D1D53A6" modified="2024-05-29" version="1">MKFTTILAALCTLTVCAPVADNTRLEKRNYGGQRFGGNRDTIIIQINDNNGFNQGRNEQQQQGNDGIDLTVLNFALTLEFLEATFYADGLNRFDENRFLQEGFAGVRDQVNLVSFHEATHVKFLQDTIRATFGENQDVPSCRFNFEESLRDVKSMLSTALVFEKVGVAAYDGAISLIQRDIFKTAGAAIATIEGRHAAALNIIARQLPVPNSFDTPLGLRSVVTLVAPFIAGCDFQLPAQPFQSALTLEQEFGRWGNNVALGFSGDIVEGQTLHCNFQVGISHFRTQIQLERRGNGLLAQCLVPNELKGNFEATVFVVDEDRDIGITEDDHVLAGPAFLPLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2R7</accession>
    <name>A0AAD5U2R7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal RNA-processing protein 7 A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RRP7A</name>
        <name evidence="4" type="ORF">HK099_002130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000169">
        <property type="protein sequence ID" value="KAJ3222576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2R7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040447">
        <property type="entry name" value="RRM_Rrp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024326">
        <property type="entry name" value="RRP7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17799">
        <property type="entry name" value="RRM_Rrp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12923">
        <property type="entry name" value="RRP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rrp7 RRM-like N-terminal" evidence="3">
        <location>
            <begin position="25"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="2">
        <location>
            <begin position="166"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="32700" checksum="17584F9D689B3CF7" modified="2024-05-29" version="1">MIKNFKNTLKTEDTNLIPLEKLGDYLILPVNLNKEVEHFIYFKKHNKKNSEKNNKLSKTIFLLNLPVDTSKQHLCRLFRKCGQIDNIIFNSKESSIESNNFNWLPLSSGSSCHLTFVTEEGIEKALDMKQRLRVWSDDFKDPFNDNEEQVQPQLYGFTKYIELFKSSKPSQNILQKNVEIYLKAFDELQAEKKLNLQAKKNLPDEDGFITVVSKSKQKMETKSDNKKLKKKKELVDFYRFQMRDTKRQQLADLRTKFEQDKKKIEILKKARKFKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2T0</accession>
    <name>A0AAD5U2T0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006172</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000517">
        <property type="protein sequence ID" value="KAJ3215828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2T0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="36"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="149" mass="17101" checksum="DD62AB80F77C16C7" modified="2024-05-29" version="1">MPLILHSVASDNLLTDILENILEVEQQQPETKTSLKRPVNSIPQLNVSENEAEYYVQVDLPGVSKDQIDLSMNAGNILILKGERKITLEQKDTDKYHISERTFGKFERRLRLPNCINLDDVDASLENGVLTLRYAKKRKIDEKKKILIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U337</accession>
    <name>A0AAD5U337_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Carnitine O-acetyltransferase, mitochondrial</fullName>
            <ecNumber evidence="16">2.3.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">CAT2_2</name>
        <name evidence="21" type="ORF">HK099_004903</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA</text>
            <dbReference type="Rhea" id="RHEA:21136"/>
            <dbReference type="ChEBI" id="CHEBI:16347"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57589"/>
            <dbReference type="EC" id="2.3.1.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.7" evidence="16"/>
    <dbReference type="EMBL" id="JADGJW010000361">
        <property type="protein sequence ID" value="KAJ3218879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U337"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.70:FF:000007">
        <property type="entry name" value="Carnitine O-acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 19" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="20">
        <location>
            <begin position="46"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00053195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00066910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00073438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3218879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="623" mass="71418" checksum="BB476559BD04D137" modified="2024-05-29" version="1">MNFKRFISGSNKILTNSTLQISNTSKSMSKFSTKITYSHQSTLPRLPVPELKETCETYLKSLEPILTNQQYERSLMAVKDFLKPGGKGEELQKLLKDRQNKYSNSSWLIDWWNDYAYMGYRDPIVVWVSYFWVFKDDKFRKDPSARAASIARGAMQFREELINETLIPDSTKAGPLCMDQYRYMFNSTRIPKIPSDITHLADPNQNNHAVVIRKNQFFTIDLKVNGRILSTNELESQFKKIYEMAGTEEHTPLGILTTENRDIWTATRDELLLNPLNKKSLEIIENSVFAICLDDTKPVTREELSRACWHGDGKNRFFDKSLQFIIFDNGKAGFNGEHSRMDATPPDRMCNTFLHNIFTGKFDDGNSHAPITLPLPEKLKFDLTNQKTQIAVAKKNFNELIDKHDLKVCVFEGYGKNLIKKFGVSPDAYAQMAIQLAYFKLMGKCDPTYESAQTKKYLFGRTETCRSVSNESVAWVKAMENPHLSDVEKGQLGRKAIASQSTYMRKAVDGKGVDRHLLGLRLLLKPDEPKPEIFADPAYSRSSHWNLSTSQITSEYYEGYGWGEVVPDGWGCAYMVKNNSLHFNLVSLKLGNETFRHYFHEALNEMKVVFEKTIPELTPKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U351</accession>
    <name>A0AAD5U351_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HRR25</name>
        <name evidence="14" type="ORF">HK099_005834</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000474">
        <property type="protein sequence ID" value="KAJ3216520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U351"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000159">
        <property type="entry name" value="Casein kinase I hhp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="25"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="315"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="345"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3216520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="395" mass="44920" checksum="11E1500DCE403695" modified="2024-05-29" version="1">MANYNNTQIQGPPSSLSELRVGNKYRLGRKIGSGSFGDIYLGTNIVNGEDVAIKMESVKAKHPQLEYEARVYKSLAGGVGIPFVRWFGREVDYNCMVLDLLGPSLEDLFNFCGRKLSLKSVLLLADQLVSRIEYIHSKNFLHRDIKPDNFLMGLGKRGNQVNCIDFGLAKKYRDPRTHLHIPYKENKNLTGTARYASINTHLGVEQSRRDDLESLGYVLMYFCRGSLPWQGLKAATKKQKYDRIMEKKMTTPTEILCRGYPNEFAIYLNYSRSLRFDDKPDYNYLRKLFRDLFIREGYHYDYVFDWTVVKYQQEGKEPPEEANDARPEQASSSRAAQPISAPRRSGTTPTGVAQSSRPQTQQTYPVVQAPPDSQNYYGNQAPQAGARNGSGPGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U356</accession>
    <name>A0AAD5U356_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001817</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000156">
        <property type="protein sequence ID" value="KAJ3222853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U356"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="624"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="733" mass="83980" checksum="0B39C3BCFAA22EB8" modified="2024-05-29" version="1">MNLVGKINETNYTSRIIGRFQRLKCIKHPSLCQYVEILKSRNERIYIISESFPTTLKSIYVANGGRLKNLDTLRRLAVEILEVLLYLESLNISHRNICSDNILISEDGGVKLSNWGLNAMSGNGEDVPFPIGHPMYLPPESIFSYDALKYTFNPKADVWSLGILLLELYYGENFFGLNDSNDIQSIFGQLERWIFPDANSSGWKYNSLEELFDKQEFEIDFELRSFIKSCLTVDIGSRPSLEEIFSHDFIKQFVNSLAKKNQLYKRAPVLLSSFAKPVTASENTSDPFDILNLNEIFHLWLLSINGNIDAELIKQGSSTIPSMEKIPNLIQVELDLEATLDSALPHVNRLYSDKTYLISLDHLRRVCLESSNLEVSPKDNLRKGSSFSQLLLDTFDEVLNSPLAIKNYRAEDWKKNPEWKHENLNNDEEQNLKRLYDQRIQLKAKEKSVAYQYQRIKLFKKLLTEFPLSKNEIRAESLIDIPPVPTGPRYSTLSPGLKPELYAISWVMTLFSHVFPLDKIYHLWDAFLTGPPFPQLYAGYAILQHFRDSLTNQDFNSCMLLFSDVSAVDIEEITHVLFKTSRFTPPSALSHLEFFDQSVNSDIDNLNLPQELSFRISLNDFKEMKANSLVFDIRDPANFELAHIPYSYQIKIENFQQIFSLLKNIGKNFIFVVVICDDDVKGGKLANLLVNAKLRRVCVLHASMAGMEYVEQHLCSCICPTMDGIVKCLNGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3J4</accession>
    <name>A0AAD5U3J4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000137">
        <property type="protein sequence ID" value="KAJ3223256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3J4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620:SF1">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="51"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="248" mass="28974" checksum="9392FD396E1686FD" modified="2024-05-29" version="1">MSNSSSTKTSSNNNSSSTESDWEKSLRLESNSFNQEKEVDRILKIHKITENPVELLELSDDFYVDFQIDLNLLKKVYRSKSLLVHPDKNKHPRAGEAFELMKQASNWLEDKEQRSGLISMAKEARAIVFHQERINVKPKDQPPKTSYLLGEPVKEEELIDIGLVKAEFKKNPKLLFKVKNELRKVLKSLQTRNEIRQKNEVSTKTKELELAGKERKRKADERISEEKMEKDAGDWRSFQKNLKKKKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3R0</accession>
    <name>A0AAD5U3R0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003239</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000215">
        <property type="protein sequence ID" value="KAJ3221683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3R0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF74">
        <property type="entry name" value="AGR407CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="47"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="454" mass="50834" checksum="BB0AB5EADAC02508" modified="2024-05-29" version="1">MLLSIFKYYTFFLFTSAAYFFYPHAPIKPENQNTNIPTHFNFSLGGLIVELSIGNGISRNAEKFQVLIDTGSSNFFLPSSKCKNNIIGDEENCGKGLNEDLSKSVDENLIFNKNQYKKFVVSKGKEFISYADASTCDGIGIQDILTLGSLRSSINLELATMQYGDDTAGNKNSSHLIKTRAGGFHGIGILGLGFPELNSVGFLPPVQVFYKNDLLTKQLIGLYFGKNSASNSISEGEVSLGWINPTAFFPFPLVYIPITTSLPGYPKEWRIHLQSLYMNGTYFGDYSNMNHEREVLIDSGNPYITLPARIASKINLSILQTNNFGMITENCFLNSSSKQFPLLKFQFNNFNFTLSHRYYLKFNKEENGVCESLIKGKRDENLKFPSSFGQPFLKFYFSIFDYSNQRIGFAIANHNGFVKGVGKVTGEGNYLVSSGSLPLYSVYYITLLLLMLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3V4</accession>
    <name>A0AAD5U3V4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000419">
        <property type="protein sequence ID" value="KAJ3217598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00761">
        <property type="entry name" value="Glyco_tranf_GTA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002859">
        <property type="entry name" value="PKD/REJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22916">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22916:SF30">
        <property type="entry name" value="IPT_TIG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02010">
        <property type="entry name" value="REJ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4403"/>
            <end position="4426"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="574"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="PKD/REJ-like" evidence="4">
        <location>
            <begin position="2407"/>
            <end position="2638"/>
        </location>
    </feature>
    <feature type="domain" description="PKD/REJ-like" evidence="4">
        <location>
            <begin position="3576"/>
            <end position="3951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="4542"/>
            <end position="4582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="4559"/>
            <end position="4582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="4582" mass="503481" checksum="61AAD4D49F134F25" modified="2024-05-29" version="1">[encoded data, 4582 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U422</accession>
    <name>A0AAD5U422_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003765</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000250">
        <property type="protein sequence ID" value="KAJ3221118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U422"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF40">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="7">
        <location>
            <begin position="280"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="641" mass="73699" checksum="145DDA3610F18952" modified="2024-05-29" version="1">MEISFHDSFHKLQLGKRESLIPFFPVDLGDLMNLTLVWMRAALTMILLSYTIYLARTKKGHFQKFYKWTIILTLIWSTDVTLKLLQLKLMHSFSEYPKFIDTALQTINIVSFLFVAAANLFWEIICFFPILHDWDSRAKFNGTCGEACLYYCGKKNDGVLSTIFVSSSKDNRSLFLALILTVKLMDMAKIITGNVPITKMEITPGSYFSRKTSQISDFPSYHETGEIGESQRLSEFPSSFPEETSPSFASSCATERHVGRNTDFYNNIISSQMHSFCDETFVKTNATAFCLKGRPYMICGANFWSAMNLGMKNEFGGNRDRLERELIFMKKIGLNNLRSEPFRIKPSLIPNVETYNENVFEGLDYALDAFSRHGFTAVMVLNNFWHWSGGFCQYVSWAENSRIPYPDSPLDWPALTLYGEKFYSNKKCQKWFKSHILTLMNRRNTVNGKIYKNDPTIFSWEHANEPQNPPASWIEDIASFIKSISSNHLVTVGLEGKEMDKEIFLKQHISSFVDYTTGHCWVENWGIYDGMDPSTENLNNAINFAKNFANNLGKWSKEDLKKPFVMEEFGMARDGWTQISRYDYRATVLNRNLYFKSLFETIVNLAEDKAATGWCFWAFAGEGRPNKEDDLIGDPPHEVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4J1</accession>
    <name>A0AAD5U4J1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">General transcription and DNA repair factor IIH subunit TFB4</fullName>
            <shortName evidence="13">TFIIH subunit TFB4</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">RNA polymerase II transcription factor B subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">TFB4</name>
        <name evidence="14" type="ORF">HK099_003372</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the TFB4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000221">
        <property type="protein sequence ID" value="KAJ3221585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4J1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004600">
        <property type="entry name" value="TFIIH_Tfb4/GTF2H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03850">
        <property type="entry name" value="Tfb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 13" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3221585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="263" mass="30242" checksum="51AFF3C7EDB152F0" modified="2024-05-29" version="1">MSGESIDFISVIIDLNPYIWSASKLSLEQTINHILIFVNSHVSLNYNNQVAVFYSHPNSTDFLFPKHSESLDKKLEARNKPGNAYKQFWHINEQILFNLKALASLDTEEEEFKPSLLSNTISMALTYINRIIRKYEPQTVNSRIIIVSVSPDIPSQYITIMNNIFCAQRLMIKMDICKLLNEDSVFLQQAAYLTSGVYVKVEYPERLIHYLMHSFLPNSSMRETLALRSGDQVDFRAACFCHKKIVDVGFVCSVCLSSKEFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Y4</accession>
    <name>A0AAD5U4Y4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="24">Guanine nucleotide-binding protein alpha-16 subunit</fullName>
            <ecNumber evidence="5">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="primary">GFA1_1</name>
        <name evidence="31" type="ORF">HK099_003058</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="31" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="31">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. In the 1-cell embryo, probably together with goa-1, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisons, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="31">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000206">
        <property type="protein sequence ID" value="KAJ3221836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00714">
        <property type="entry name" value="GFAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000001">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002307">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000002">
        <property type="entry name" value="guanine nucleotide-binding protein G(Q) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047084">
        <property type="entry name" value="GFAT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="20" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="17 25" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="14 26" id="KW-0460">Magnesium</keyword>
    <keyword evidence="18 28" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 26" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12 25" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="19" id="KW-0807">Transducer</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 28" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16 28" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="28">
        <location>
            <begin position="1492"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="28">
        <location>
            <begin position="1529"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="28">
        <location>
            <begin position="1559"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="27">
        <location>
            <begin position="580"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="29">
        <location>
            <begin position="740"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="30">
        <location>
            <begin position="1102"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="30">
        <location>
            <begin position="1274"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <begin position="28"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <begin position="135"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <begin position="154"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <begin position="179"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <begin position="248"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="31">
        <location>
            <position position="1601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00029805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00033302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00059820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00069088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="KAJ3221836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1601" mass="181499" checksum="26CE3855B870FF32" modified="2024-05-29" version="1" fragment="single">NDDIENQLKQEKLAEAKEVKMLLLGAGESGKSTILKQMKLIHDSGYSNEEKEAFKEIIFSNTVQSMRVILEAMANMGIALGTPSNEAHQQVILDLPSQIEAEVFPAEVAAAVKNLWVDSGVQACFNRAREYQLNDSAIERIALPDYIPTDQDVLRSRVKTTGITESSFHIGDLTYKLYDVGGQRSERKKWIHCFENVTAIVFLVAISEYDQVLVEDETVNRMQESLTLFDSICNSRWFVKTSMILFLNKIDLFKIKLAKSPMGKYFPDYTGSDDFESASEYILNRFVALNQSDKKQVYTHFTCATDTSQIKFVMAAVNDIIIQSNLRDCEKLVTYDSNLPHKAFSHYKELRNDEKLSTVSQTDYSKLMAYVHSYTVVPNFDKSLRYEHLTSIENDMRKNLVPHNHYTFSMLVDIYAKEGQLEKINKLREEFNFEVDPANLVIATAIQLETAEEGIKKELTSELKKHFDACVQLHGWSKARICLMQAYANLDKEKLLIKQFKHLNDKKTKRPETAAYKVMIKYYCEKGKIATAIKYLSKIKDRQPLSSLFVLPIEGLVEKKEFKEAEILLKKLEKNKRFFNLNLYQAKIKCLASKNQYQLVWETYEKMIKAGFHPTEEIYETFSNLYNTEKQLKNLKSKHLKALKLDLNEDKINFLIKCFGSCKNELGASFMESQLISKKLTLKNETLEFLSVAFFKEKKKENKIASGLKLLDKLKENKHRISAENFEIIRSRLSSLKDEEGIFGYLNYLVEKDRKEIINYLLTGLSRLEYRGYDSAGIAIDGDSEGCDALLFKEVGKVAALKKKIFATDGLDQDKTFLAHTGMAHTRWATHGQPSVVNCHPHRSDPKNEFVVVHNGIITNYKELRLVLEKKGYKFESDTDTECIAKLAKYIFDSQKGGAQLSFTSLTKAVIKELEGAFAILLKSSHYPHEIVAARKGSPLLIGVKTQKKLKVDFVDVEFGAGNETNKSEIESGSDASGKVKRTQSRAFLTEDGLPQPIEYFLASDPSAIVEHTKRVMYLEDDDIAHISAGDLHIHRVKPGDGLTTVRTIQTLEMEIAEIMKGSFDHFMQKEIFEQPESIVNTMRGRVNFDTGKVNLGGLKAYLSTIRRCRRLVFIACGTSFHSCVATRSIFEELTEIPINLELASDFLDRKSPIFRDDVCVFVSQSGETADTILALRYSLERGALCLGVTNTVGSSISRETHCGVHINAGPEIGVASTKAYTSQFLALVLIALQLSEDRISLKERHQDILKELYELPTKIKETLAIDSELRDLAKNELLKEKSLLIMGRGYQNATCLEGALKIKEISYMHSEGILAGELKHGPLALIDENMGDANINRNFTTIKVPQTVDCLQGILTVIPLQLLSYHLAVLHGVDVDFPRIYNKGNEFVNENTNLLHHNCDLNSTQTLNSTFYDSEEYARLSSSSLVEHYKKKNVTFNLGKNVTKTFFILFGLNVAYHNSSSIYNNSNTSSKVFSNDVPLTAQNSFSFVDDFSLGDIFGYTSIVLFILARFPQIFQNYKNKSVEGLEILMFYFALLGNFTFSVSILLESIEYEYIKRNLPWLLGAISVSFADIIILIQFFYYNKRVTAREAKADDVVAGLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5A4</accession>
    <name>A0AAD5U5A4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Intraflagellar transport protein 22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RABL5</name>
        <name evidence="1" type="ORF">HK099_007746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5A4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="181" mass="20472" checksum="7B4CB03A62C7A1E6" modified="2024-05-29" version="1">MINKITTFIVGPSKVGKSFISSSLADVSESLSSEYHPTQGVRILEFERKIKQKNKEVPVSIELWDCSGDLKFQPVWSSVSNSANAVLYVFSPDSKQEKELDLWYENFSFLKDTQFAVFGNTINGSVKKSTPKFGSDLNKVTPVFTSNNDPNLIKAEFDKLINKAYLAWVDNREKEEQSMLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5A7</accession>
    <name>A0AAD5U5A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000292">
        <property type="protein sequence ID" value="KAJ3220551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="213" mass="25614" checksum="C3A477A3F51DF2FF" modified="2024-05-29" version="1">MSKKGILHSDEYTLYKALFPKTATAIILNSNHEHFYEECKQRFPERFNFEILKNLFDTWISSGENNANSVIEILNLKNINFYINDSLIWKTDAIVQSVKFENKFFLTTSLKFSNDEFLYPELSKFQSLRKEIKRHRSDSWCLLEKKEYEGKFDNISKWARDFFNSEIETQFFYNFELERINFIFKKKGVEFGDKLNVTFEPGYPENDFVEVWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5B5</accession>
    <name>A0AAD5U5B5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007592</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000075">
        <property type="protein sequence ID" value="KAJ3224963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5B5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF7">
        <property type="entry name" value="FUNGAL TRANSCRIPTIONAL REGULATORY PROTEIN, N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="265" mass="30637" checksum="B073A04D3C089DF2" modified="2024-05-29" version="1">MMQPLQSQQFQKAPFSPLQILDSCPSTPKPQQLEYITPPQSIDYHLLAEDAKKRVQVKKACANCQKSCKKCDEIRPCQRCIRLGEEASCIDTVRKERRKGTKRGPYKKKSLDFESALRAPKKFKSLPVEYMKFNGHHFENFQNSELFSETFIKKEKIDMIESNGEYYRFDNYYEEEGGEQKLKILSEICNLELFNNIEERKYQKIENEVTTFKPAYLFSSNNTFSFNDVGCDDGTDIDTTNFAASPKANKGFEELINAVNAFKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5N7</accession>
    <name>A0AAD5U5N7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RasGEF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RALGPS2_1</name>
        <name evidence="7" type="ORF">HK099_000711</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000118">
        <property type="protein sequence ID" value="KAJ3223755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5N7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1001"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="6">
        <location>
            <begin position="20"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="304"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="359"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="599"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1144" mass="128842" checksum="6F1FA64EB01C518D" modified="2024-05-29" version="1">MELQPQENKQTTESNSEIFPAKEIAKQLCIIDSGLFKKIQRSEFASLKWTGSEKLEKAPHIVEMTGAFNDISGWVANEILSAASSQKRLEKIVYYIHVAKNCVDFGNFNGMYTILGGLQCTPVFRLEKTWELLEKFYKKEKALMDKLNEISSHDRNSEMYRKKLTASKKPCIPYLGIFLADLTFLNEALKKEMNEARTQAVNDRKLVISNLLDEIEVYQQSCIFPFEFIPNIISTIVSRKFDQKLEKTLYELSYKVEEKGSKSKGESTPQSVSLKGGELGGNWLGSIFGFQYSSNKELLPLTPNTSKALPKLKGSSKSFVSNETEAESPTTNHPITDHSRKFRGVLKQLSSVRFLADGDEEQESYGHQRSKSSEPYIFKKQESESNADRGGRIRSDPSIPDVSGINNDQNVNIEKKNSLLTSEEELLPDFSEEDASESGSEEGEDENIDAIVSKSIPNLNEEIFGMHGFLYVTFDKSTDEKKKWKKRWGRLEGHVLVLTKISRNRRFRPQNLKVNTSTSIQNLNEFNPKREKLKPLELKSKKEHMKISLFSSSVDLNEKKFSTSPTPTAAHSSQYLCTSPTSAKSTNFLNSIPLTNAKEATGSLDTNSKYEDGEEVEQHQQKGDRQQTFKKNWSENMRNKIISSFDSLKSPVASKEQHTLIPLNVEAVPVSTSTATPTTKYLLQVECKDEFIPASGYLMEENSNSTLAHTTDPPSLLTSLRQRISNLIEPTIEVASDEEDNSNYNFDEDECKIFKTSIIPCVMLLFGVLLIGLAAWPLLPHEETVSDLKLDQGERSLIEISPYWFKSVKLKMETKNSDLQDKPLLIYLMHQKPLVTKTTTIYRRICPILDRKNYYSVSHWELFSTSKMYLNWNIYDGSENEPFSGPTYSEIDPIPISKCVLANVKDECNFDLPEWAITTFVLLNSPSNLKGKNLKTLNDLETADDNILPLFGSQRKSLSDYRISISDGMGMDYSPAFKVSYTTVSRYCVLQSIESKNFLEVLYFLLGGHYVAIFALATGLFATLAILGCTCSLLSYLGSKICPSYFGDETNEELEPLLDYNGYGTLPADFEPLPLYIPSPIPTASTLQNDEITESITLDVDPPDFVAYIKNNGCSTIPLNGGTEIDTCSLESEVAYPSSPPPQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5R6</accession>
    <name>A0AAD5U5R6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uracil-DNA glycosylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000280</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5R6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097510">
        <property type="term" value="P:base-excision repair, AP site formation via deaminated base removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF8">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="5">
        <location>
            <begin position="142"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="307" mass="35423" checksum="A3E37C034D71F333" modified="2024-05-29" version="1">MGSGKEFRPGGRMEGKQQGFVYSKNRTTKRYTGSKNKRAIFEQVYAASKPTTVYKESPERDAQDVYKSSIVGESPGVYRCPVYNSSSTITQEQHISESRHSVDNQSYNIAPAWNIDISFVKKLFSVNFFPKNFFKIFHTIPYHSIKVVIIGQSPYPDPRHACGIAFQVPDDVIICPVSLKTLFKELESDIGIPKLRIRDCIKYWVSQGIFLTNASLTIGTGEPEYLRNHKYFWQDFSIEFIKRVSILKCPIILLGKDSWELEKYITHNKYLKFYHPASRDNQFDGCKMFSKINNLLDTPFDWLCRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5U0</accession>
    <name>A0AAD5U5U0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Splicing factor 3B subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">SF3B1</name>
        <name evidence="21" type="ORF">HK099_002565</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SF3B1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000186">
        <property type="protein sequence ID" value="KAJ3222210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000066">
        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000069">
        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000073">
        <property type="entry name" value="Splicing factor 3b, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015016">
        <property type="entry name" value="SF3b_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038737">
        <property type="entry name" value="SF3b_su1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00798">
        <property type="entry name" value="mtc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12097">
        <property type="entry name" value="SPLICING FACTOR 3B, SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08920">
        <property type="entry name" value="SF3b1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="14" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Splicing factor 3B subunit 1" evidence="19">
        <location>
            <begin position="513"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="20">
        <location>
            <begin position="1286"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="491"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="444"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="491"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF08920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3222210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1556" mass="175219" checksum="99C13B71286E73BE" modified="2024-05-29" version="1">MVERIDLSKPRYDQSTYIGRLRHFAALTSPLTLFATDKQLNAAKTLITDYQSGKILNVDTEKLWNAKLLIDSTFHPDTGEKVFLPFRMSSFMPTNLLVLAGMLAPNPTIASIVFWHWTNQSVNVAFNYFNANKSTKMTPSETVVAYTSACGSSVAVAVGLSEALKRAKNLSSGARSILSKTVPFTAVAVAGVANVFLMRRKELIEGIDVRDKEGNVLGKSKEAGKHAITQVAISRVATSFPLLIFPPFIMSQLQKSNFLKSNPRLVGPLNLSGTAQLPVENVESQFKNFKLKDGSKVETVYFNRDRNIDDEIKAQQMEREGKAKLNAISFDQQIYSVNDKKNSELYNMEIDDNFDDDDEEQPSTFNKKPGLSSYTAPKNLFNEMNAEGNDDIDPFANTKKSKKIADSMNEYQLRGRANRSQLSPERVDAFGKSSENARSYGEVLKEAELDREEHRVKKKIEENRREAKKEIEVVDNEGAAAKTKAIVAERKKRWDEKPTEEDEVKKSEWDEETTTEKRSKWDETPVAAKTKTSRWDATPTSKNYQFGATPVGNIGLQTPLPGDVPVPMTPQQSKEMRYEREMDIRNRYLSDEDLDAVLPAQGYKILEPPPTYQPIRTPARKLSATPTPIPGQMGAGFVMQEDTIYSTSQSGDLIPEIPGMTGTLSFFKEEDMKHFGKLMDKKKEEDMSVEELKERKIMRLLLKIKNGEPPARKTALRQITEKAREFGAAALFNQILPLFISETLEHQERHLLVKVIDRILYKLDDLVRPYVHKILHVIEPMLIDEDYYARVEAREIISNLSKAAGLATMIATMRPDIDNVDEFVRNTTARAFAVVASSLGIPALLPFLKAVCKSKKSWQARHTGIKIIQQIAILIGCAVLPHLKSLVDAVKDGLKDEQQKVKTMTALAISALAEAASPYGVESFDEALIPLWDGIQKQRGKSLASFLKAVGFIIPLMSSDHASHFTKNIMGVLIREFASPDEEMKKIVLKVVKQCVSTEGVEASYIKKEMLPHFFKQFWVRWMALDRRNSKQLVETTVEIAQKVGVMEIVQRIVTELKNESEPYRKMVMEVITKVIETLGSADITPRMEEILVDGILFAFQEQTVEDVIMLNGFGTIVTSLGVRVRPYLQQIASTILWRLNNKSAKVRQQAADLISKIAGVMQLCGEEKLIGTLGQVLYEYLGEEYPEVLGSIIGGLKAICNVCGMSSMTPPIKDLLPRLTPILKNRHEKVQENVIELVGKIADRGADFVSAREWMRICFELLDMLKAHKKSIRRATVLTFGYIAKAIGPQDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALIDRDLVHRQTACSAVKHIALGCFGLNCEDALIHLLNYVWPNIFETSPHVINSVIEAVDALRVALGPGVLLQYVVQGLFHPARRVREVYWKIYNNMYIGSQDKMISFYPRLENDERNMYQRCELDLVVYVYYMLIYQMTRLSIKLKEEKGKKIKVTQKETNCKSSGYTASELVVTSRGMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5U1</accession>
    <name>A0AAD5U5U1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytoskeleton associated protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CKAP5</name>
        <name evidence="12" type="ORF">HK099_006752</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TOG/XMAP215 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000060">
        <property type="protein sequence ID" value="KAJ3225479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990498">
        <property type="term" value="C:mitotic spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099070">
        <property type="term" value="C:static microtubule bundle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061863">
        <property type="term" value="F:microtubule plus end polymerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030951">
        <property type="term" value="P:establishment or maintenance of microtubule cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990571">
        <property type="term" value="P:meiotic centromere clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000022">
        <property type="term" value="P:mitotic spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000019">
        <property type="entry name" value="Cytoskeleton-associated protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000050">
        <property type="entry name" value="Cytoskeleton-associated protein 5 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000063">
        <property type="entry name" value="Putative cytoskeleton-associated protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057978">
        <property type="entry name" value="TPR_DAAF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045110">
        <property type="entry name" value="XMAP215"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048491">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25757">
        <property type="entry name" value="TPR_DNAAF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21041">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="11">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="11">
        <location>
            <begin position="265"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="9">
        <location>
            <begin position="436"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="11">
        <location>
            <begin position="609"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="11">
        <location>
            <begin position="873"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="11">
        <location>
            <begin position="1226"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="523"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2017"/>
            <end position="2069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="2017"/>
            <end position="2052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3225479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2084" mass="234030" checksum="AFACF6175045E0C8" modified="2024-05-29" version="1">MEEANEKIDFNSIPLQERLVHKKWDARQHAYLELAKIFKNLPADSENEYKKYQEHLKKIVVDTNLIAQETGIQTLLNFITYSPHPDRTTKVLVPLLIEKCVASMRAGTRAKTLECLLMYIEIDTAEPVIECLIAGLDHKNPKITTACFFALKEAVRAFGVKVVQPKLILNKLSKAFDHKDKNVRAEGTALAIELYKYLGANTMNQFLSDLKPVQLKELTEEFEKIPNEKRTPERFLRSEQQNKNENSAFQDNIEAEVAEAPDPYEFVDAVPILDKIPKTFYEEMASPKWQLRKEALTNLLAIVQSPKIEDGKYGELIALLGKKVADNNIVVATLSTNCITCIAKGLRNNFQQYKGLVISQLIERSKEKKTNVIEAVRSALDAVFASYGTINETLAEDMSAAFLHKNPQVKVESIMWFIRSLKLSKKTPGKSELKSFIENLMTNLDDGDNNVRNASAEGLGTLLKSLGERSILNTYLEKVDPIKMQKIKEFCEKAETTMKGKPGVVKSNTGAINNINQKIAMEQPTVKQLGKPKSRQASATGSKKILAKKKAEETTSTKPSQNFSAASSSKINNLDLVFKFTDDDAENFLNEIMQVDDVEENDSTIGLVDGGNEEMDSAAPVIALKGYQDLSSSNWKLRLAAMQLLLNKLKSDSVRNIEAELIFRGLLKKPGFKENNFQVMTNFLQIIKFCVLNFTCSPGSASLVISGLTEKLGDMKVKKIAGDCLASLAEATTFGFVLSQMYETVKKQKSPKVIADCLNYIQQTLLEFGAKGINLKDLIEFTKVFLGNNNQTVRTNAINLLKTLRIFVGAEIKIFVADMNPSILSTINAEFEKVENQKPPNPTRFSKLLSVPSSHNNPASGDRVIEEEDMVDNLFPRVDITSKISDELVEKLSNVQWKIRKEGLEELSAIIESTNRRIKSDLGNDLIPALKARLGDANRNLAVITLDILSVLAISVGKPFDKYSKQICSSVMSCLSENKSQIRGAAIQALDSIYTASGFENMISSISQSLLLEQPLLRRDLLKWCAEKLEECESQDRIKLDQEQTLPILHPVFLCLQDRNNDVRKFSQTLLGTLVKFLGYPVVKDRASEFFHGSQLQAILAFVEQAKPSTVATGKIRAGTPSNLIKANTVNDELLQPSGVSKIGGEIKNVKKISKPGNVSQIFSTQKKDAEVPLGKKCFPILSSDFRMKELRGEKDRGMNKWVFESPRKELINFLQEQCEGNFFNEYREKDYLLALSTLIEPLVSKESLEEIFGITLEELQSRYVANADLIFKYVTLRFFDTNTSMLIKCLELLEGLISVLDDVGYHLTEYEASSFLPFFINKAGDSKETMRLKIRGIMKQFCRIYPASKMFAYILKGLESKNARTRIECLEELATLIQRNGLSVCGSPSKAFPIVAAQIADRDAGVRNSAINVVTQAYVLVGGEQVFKYIGRIADKDKSLLEEKFKRMPQPSQSHSFSNNNEKNEVLETENVEFSQRISAPENIRDLPNLGRESPKSSIKNEFSLDFEKFEFPNSKTVVAASDSNFVGRSTYSLESENNMLDFVINQVTDTDPDISITALKNLEKALSTSPESLEPHIDDIVRSITLQIRIAFTAADISNPAISRLCKHLVNMLVQLFSNSKLAKLLSRELLHQCVKELINRLLDKNIDKIENSSQLTKAVNVLMVRILESCDRNDTFSVLLEILDTSSQLLKDCRPDEISRQSKYVELVMKCLWKLTKIIPQLVQSKTLRINQLLLDVHNFLVSSPPNEWKRRATEKLIPQADMPLRTIKTILHEFATLLGDNVFEHLELIPDVHTSTAVAYLKSMVEASRKKNEKTSPVPQVKLGGMVTAQTESSIPATSKKEALSAVDDSADVYSTEIAITTDRFLSEDDAKRELAEIFDKIRDKNLTKQGISELYVFQTNFGTSRMVENLIEEFICSTGTYFQGYIRRGLKALADEESSVKHGTSMTSSVTAMTSMPFKRERPASMIARITNLYTEKLEKLQQKFRGEVIHLIYPVNLHTFAFKQSQSVTAEDSDSPTIIRSSSLRNESKSRPLSTDSHFAQSSSLTREQRARGNEGEVQSYEALKERLNKMKLNMSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6W2</accession>
    <name>A0AAD5U6W2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000035">
        <property type="protein sequence ID" value="KAJ3226488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6W2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028042">
        <property type="entry name" value="DUF4639"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34438:SF1">
        <property type="entry name" value="CHROMOSOME 2 OPEN READING FRAME 81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34438">
        <property type="entry name" value="SI:DKEY-97L20.6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15479">
        <property type="entry name" value="DUF4639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="472" mass="53446" checksum="DE3A29BF4DDF5C47" modified="2024-05-29" version="1">MATKEEWFAIVEVEEGEQLVSTLLDEILQKAQEVIFERHIESQVLPYAVQFAKETLLNLIDWNFFKHDHGTIDPNTWTPDKEHEPIIIDSWARGAIPTKKPPQIITNNLNKKQNLIENSSFNLLNDNTNIENSKDFDSNNSIKSQKNPVAKLENSALLSVKIQNTSKTGEARGSSSSNFSIKPGNSSSMTAIKRRSYKRSPINKPIDTVESSQTPVTVFEQSIQEENKRTLNRIKNVEKDGAKTDFGYDIDGRIIAIKKISHQNTMNQKIKIKILKEEDNPEVESKGTLTKNRFNANRHSAEKKVVDENVKKISNSKSKHNNNNLKLKSSLTNLNNNFNFNNLGEEKIYEFIQDSSLDITPLVETMRLAPGVTLKEGEITKKGHAFQRKVKDIPINLKPTINSQLTNFKLLKPISSNLKNSELHLNKVLGKVKNSLKLINVGEHIDADLQRNQTSKILPDIKEQRTTGQVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U750</accession>
    <name>A0AAD5U750_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003967</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U750"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140824">
        <property type="term" value="F:thioredoxin-dependent peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000010">
        <property type="entry name" value="Glutathione peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3226855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="165" mass="18753" checksum="49D78DBF64700FF7" modified="2024-05-29" version="1">MTAQNLYSLTANNIKGQKFNFDELKGKTVLIVNVASKCGYTNQYGGLQKLYEKYHSRGLEILGFPCNQFLWQEPGNGDEIQSFCTLNYGVNFPIMEKIEVNGSGASPVYDYLKSQKDQPGKLFGRTRDVKWNFEKFLIDKNGNVVNRFGSSFTPQQLEAEIEKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7A5</accession>
    <name>A0AAD5U7A5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">JmjC domain-containing histone demethylation protein 1</fullName>
            <ecNumber evidence="5">1.14.11.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">[Histone-H3]-lysine-36 demethylase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">JHDM1D</name>
        <name evidence="23" type="ORF">HK099_000683</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:42032"/>
            <dbReference type="Rhea" id="RHEA-COMP:9785"/>
            <dbReference type="Rhea" id="RHEA-COMP:9787"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
            <dbReference type="EC" id="1.14.11.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the JHDM1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.27" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000117">
        <property type="protein sequence ID" value="KAJ3223790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7A5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140680">
        <property type="term" value="F:histone H3K36me/H3K36me2 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041070">
        <property type="entry name" value="JHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050690">
        <property type="entry name" value="JHDM1_Histone_Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23123">
        <property type="entry name" value="PHD/F-BOX CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17811">
        <property type="entry name" value="JHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0804">Transcription</keyword>
    <keyword evidence="14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="21">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="22">
        <location>
            <begin position="193"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="657"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAJ3223790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="693" mass="80335" checksum="34295604F731F359" modified="2024-05-29" version="1">MSFCYCQSPGTEGKFMIQCDYCENWFHGDCLDPIIAEEEAEYYIKFHCKECETIRGPSIYRPPIRKSVREKPKVVYKDLHNGGKGLELRFTKLLISKEHVFKPNNFKILKGYELTKTWMEQTGFREPVIIPDPIGNFDSVSDVADSCGRDTTVDVLYVPTQSERIMTLDEWAKYFEQPEGVRTGILNVITLEISEYSIGKLVKRPTAVCEIDWIDHVWPAEIKPIQYPKVQLYCLMSVKDSYTDFHIDFGGSSVFYHILSGEKIFYFIEPTPQNLKKYELWTSNSSQGEIFFGETVPNCYKVHLTAGNTMLIPTGWIHAVFTPSDSIVIGGNFLHGYNIKGQLDIYEIEKKTMVPPKFRFPYFDTMLWYAAKTYLCILKDDPDSISDFTLEGLYPLAKYLLLVTKKLTQKPKITKEERRRIRESIPKGLKNIRKLAKSLKRTVKVELKGRFNALIAEKDEEVQQKNLNILYNDNPIQNLFNTNFSIDDNFSPTKIKNSLKSKNNNFIENLSSDSDVNSFDEIEDSWDVEELEHENLFKEEANILEDVYLDEEEDPGEKFETDFVIKKKSLFEKRKLSRSESEESVSPTTKKKKKIIIKKNFELKIDNNNNVTELKKKMNITTNNSLNLLNYNNNNIFEAKINHNALQLQRMQQSNNSTTISSNSFNKKKEKQVKAPFSSKGKVFSKLMKGMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7H9</accession>
    <name>A0AAD5U7H9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multiple myeloma tumor-associated protein 2-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002927</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7H9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019315">
        <property type="entry name" value="MMTA2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039207">
        <property type="entry name" value="MMTAG2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580:SF0">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10159">
        <property type="entry name" value="MMtag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Multiple myeloma tumor-associated protein 2-like N-terminal" evidence="3">
        <location>
            <begin position="14"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="38791" checksum="70D81AC09C70A0A5" modified="2024-05-29" version="1">METGLDAGGPVREGNRGGLGLFKWETVKEDHDRENYLGHSIHAPVGKWQVGRDLTWFAKQSKKDKELKQEAIEREKEALREAEAQAFAEALGYTGPRLTTGKNVSNEELNRVLKKNRDNEEVHKGIGFGHEKKTAYTIEEKEERSRKNEKVENLDGSEDEWVEAQPLKKIDKKSKKKEKKASKEKKKEKERNSPNLKKRGIDHEAEDKEKKKSKISENEKIRHGDSNIRLFNEKSKNSRVEEKKSNETSKHYEERRNSHNRNLSASIEIGGSYKEDKANREESYRKGDRRERRDLRYDERADYKYGSNRRNKTDEGRSKSDAEKKERYSGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7I5</accession>
    <name>A0AAD5U7I5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD repeat-containing protein 63</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">WDR63</name>
        <name evidence="7" type="ORF">HK099_006872</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000062">
        <property type="protein sequence ID" value="KAJ3225414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7I5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036156">
        <property type="term" value="C:inner dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF5">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="534"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="915" mass="103012" checksum="2687067BB3F4FC47" modified="2024-05-29" version="1">MSKANLANGSTKSLSTLTNQKSELQIQKNGSKMNSRTSIAEGSRIVPQLSKNNTEVVVHTSSDEIKNDLPTTSNTATSEAEILREERIKAGILPLFLTTATQELFKLKLGEHIQPESPFRMIPKVDLLADIQTRLMISDFQPGKQQIMDFPEEEILVHNDKDFKYGQNFFIVTTTDALNALLEPLIAKNDLEVDTLPPKPVSKKWESLGSDKEMESESVVPTREKIVVKASRKLKDFGTISKFGDRDAHDGFMECRPYRDNNYEVLRSKLSIAVQAVPELHYGESQTTWNRPINFCVQYEPILMTEAEKESTLKCNEIQQFLASVTSKFEQVLVHNELLNIFTDEYALLGEEEMTALEQGSHTHLQEYQSFTDLKHSKDKSISCIDWHPTLKGVLAISCVNKLTLDEKIEAGFNIVSKKSLILIWSFHDPIHPQLILEAPDDVTSFQFNPHDANIIACGCVNGQIALWDISDYQDKLKNNRKVRGENETTLGEKRDEKSDSQHSISVVKWIAVSSIEGSHHGPVSDLSWMPGIEISHSGEIIEGQIETTCRQLITASLDGTVFYWDTRYKKELKALDLAWKPFLRIPLSAMDNTFDYGLTKITIRGNLKETGSQINLNQPNTAVVPKDTGTTKFYCATEEGDLILADWIAEKGNEEKGQSSRVEHAFSRHFGTMSDLRRSPFFPDILLSVGGWSFHIWKENHNAGPLLSSAPSVAYVISGVWSPTRPGVFFISKTDGTIEVWDLLDRSHTPSTTQQVSSAAISYMDIHHFQGSLLGKSRSVHQFIAAGDDEGTLHILEAPRNLTKPHKNEKQFARTFFDREVRRLDYVKERKEFRIAERSKFEANAMEAAAAALAVANATPTSEKIPLIPKAKKNEKKEEVAQIVVDEEGDKLEAEYLKMERDFLELEGLIPLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U838</accession>
    <name>A0AAD5U838_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_006194</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000052">
        <property type="protein sequence ID" value="KAJ3225796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U838"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF41">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041768957" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="19"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="524"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="555"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3225796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="594" mass="68422" checksum="D9EA82D9C360BDB3" modified="2024-05-29" version="1">MKLFQTLILLLTFSAISANEHNHHYNTNEQVVVWVDTVGPFANSQETYEFTQLPYCLGEKTLLDHHHETLGEALLGVELINLGTNIQFAKNEEKEILCKTTLSNSDIKTFIYAIRNNYWHQLYVDDLTAWVFVGEEDEPLSNNDNINNVEERKQYLYTMKNFSISYNGDQIIEVNVTNLNPVHLKPDADEMHITFTYSVYWTKTDKLFSNRWAKYLDSDFFEHKIHWFSILNSFMMVIFLVGLVAVIMLRAISRDYARYDKEEGLLDLDRDLGDEYGWKQVHGDVFRSPSRLTWISAMVGTGTQLVVLSFIIILYTIMGDLYLERATILTATIFLYAVTSMISGYFGGSYYAKYGGKNWIKTMFITSGLWPGVVSGVVFSINFIAIYKTSSKAIPFFTMVAILAIWLFLIFPLTLLGAIIGRNWAGEPNFPCRVNPIPRPVPDKIWYAEPIMIILLAGILPFGSIFIETYFIFTSFWAPNKTYYVYGFMLLVFIILITVTACVSIVSTYFLLNSEDHRWHWTSFFASGSTGGYVFLYAIYYFFARTKMTGVFQTTWYFGYMGLVCFGMFIMLGTVGHLTAEKFIRKIYSNVKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8F3</accession>
    <name>A0AAD5U8F3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000045">
        <property type="protein sequence ID" value="KAJ3226049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1346"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1453"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1530"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1364"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1391"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1463"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1576"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1609" mass="172838" checksum="B406EF609C244E23" modified="2024-05-29" version="1" fragment="single">DIAVLEEATVEEPVEAEVVLDEPAAEAKETVDKAVVEETVVEEPAVEVEVIVDKAAVEEAIVNEPVEAEVIIDEPAVEAEEVVDEPAAEAEVIAEDSAVEAEEAVDKVADEEVNVDKTVVEEAVVDEPAVEAEVVDEPIVKAEVIVDEPAAEAEVIIDEPAVEAEAVVDEPAVEAEAVVDEPAAEAEETVDKTIVEEAVVDKAVVEEAIVDEPAVDAEVIVEEPVVEAIVDEPVEAEVIVDEPAAEAKETVDKAVVEETVVEEPAVEVEVIADELVVEAGETVDKAAVEETIVDEPAAEAEVIADELVVEAEETVDKAVVEEEIVDEPAEAEVIVDEFAAEAKVTVDKAVDEEAVVDKAVVKEAIVDEPAVEDEETVDKAVVEEAIVDEPGEADIVTDEAAAESDEPVVEADEMVDETVSEVEAETINDSEQSNYPLAEIQAEPSNTDAPEVKPLGRDVEIEADVEFNDHMVKSEQLAEAEVKITDSLLTTTENHQKELGNSELPRNVVKKTSGWLSGWFSKADVKSTDTTDNNTNAATKFVADEKESLNAVVTERDSELHDSVLGIQKSGSDNSGSEVNKVISDAVDEVVNEKTPLIENTYTTKPGEEKSEATSSIKEDIIASYITEAKSVEHITEVPEEVDERIVEPEFKIADVPVVQAEIIMTDEVAVEAEAGTDEPVEVKIEEAAVEAEGIADKPAADEVKVNGSFSEVEAETITESEKSEKSDTENQADAISSSEVQKVKSVARIAEAEAGVVHNGPVAESETAAEAEVLAEVIADKAFVEEAVVNEPAAVAEVIVDKAFVEEAVVNEPAAVAEVIVDEPVVEAEETVDIAVLEEATVEEPVEAEVVLDEPAAEAKETVEKAVVEETVVEEPAAVAEVIVDKAFVEEAVVNEPAAVVEVIADELVVEAEETVDKAAVEETIVDEPAAEAEVIVDEPAAEAEVIVDKAVEEAIVDESVEAEVILDAAEAEETVDKAVVEGAIVDEPVEAEVIIDEPAVEAEVIVDEPAAEAEVIVDKAVVEEATVEEPVEAEVVLDEPAAEAKETVEKAVVEETVVEEPAVEVEVIADELVVEAGETVDKAVVEEAVVDEPVEAEVIVDERAAEAEAIVPVFNAETLQLERLEPDADGFSGTVNDSVFKGNEFSTDSYKSNVAVEPPISESVSAEKKFVKESGSPEKSSWLSHIFGKKKGLETKTDDGKDDDNSALVPEKGAVLSETKEKIDATVNDVTKKEIDATVKNVNNVVIFTKKNLEFSNDEKSPGSNSAIIPSSEISKGAQRNAEVNNFESTEFVGRVKVAKRDASSISNQKKESIVKEILPSIGERKKLFETGLKPKIKESLPIEAKGKKSSTGGWFSKLVNKGNSKPTGENTFTISTSKDSSEPKPVQMISQESGPNGTKTVTKRLVKRISRLAHDGSETVEELPLEKVDKTPSDVKTVVRKTVVKKSSGVLVSSEDKTTQEGPTPSASSKLTKRIIRRVTRTVNNGEPEVIETVEEVPIDEIPEQTEFKGQPIVTRKIIRRVIRKSGGVDQEISKSVTTISPDGSEKTENFDKRRKSKERSRERTPISNLWKRSNEDIKKKKSGDFKSGDEEETRGRKLNNVPWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8Z1</accession>
    <name>A0AAD5U8Z1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008701</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000099">
        <property type="protein sequence ID" value="KAJ3224245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8Z1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051848">
        <property type="entry name" value="PGIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059">
        <property type="entry name" value="POLYGALACTURONASE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059:SF12">
        <property type="entry name" value="POLYGALACTURONASE INHIBITOR 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042036785" description="L domain-like protein" evidence="5">
        <location>
            <begin position="16"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="37802" checksum="97F0DE164ED6C3BA" modified="2024-05-29" version="1">MKILINFILFWNVFSQGVNQPSSNPVNSTISIPVNNTISNPVNNTISNPINNTSLPFNGTQSEDCKILISWLPTVFNKTDCCKSTVNLIPGTEGVLKNITCDAEGRVTALNIGTPFWETVLTNTKLPPALGQLNRLEYFALTDSNITGLIPEEFGNWTNLLGFYVFNNSLIGNIPVSFKNFKKLTEIDLTENQFSGQIDNSVFSNWPNLKGFWVDDNRFSGQVPPALQNALSLQGLGLSSNNFSGQLPDLSGLKFLGVGGGETWLNLGIPLDNTCTLEKIGSDVCFSDNLKFPDICASDNINRRCGDFVFTVPIQIGIAAGAGALVFILCIICCCCRRRPAKLEKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9B0</accession>
    <name>A0AAD5U9B0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000045">
        <property type="protein sequence ID" value="KAJ3226054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9B0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="80" mass="9328" checksum="89A1922D0AF93350" modified="2024-05-29" version="1">MKQKGSHLNWNEGNLAFYLKFKEDTVVGSRFFGDIWWNKNPSLISSNQAFQVDLPGPDRFLYQVLLLLLPCMRYGSLIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9I6</accession>
    <name>A0AAD5U9I6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Guanine nucleotide exchange factor MSS4-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002877</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9I6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.10">
        <property type="entry name" value="Metal Binding Protein, Guanine Nucleotide Exchange Factor, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007515">
        <property type="entry name" value="Mss4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011323">
        <property type="entry name" value="Mss4/transl-control_tumour"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13276">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13276:SF0">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04421">
        <property type="entry name" value="Mss4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51796">
        <property type="entry name" value="MSS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3228372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15896" checksum="A522A0E94ADA5468" modified="2024-05-29" version="1">MELKTFNELKVEDLFDSNTFLNKHFLYCNRSGCNSKIANKGVAKKVFLQGECDLKLPPTKSLNKDAPSATVSNFNPDNESPPFYWSLEDMMKFENIGFSNTVDNLKYLICADCELGPLGFRLTKNETCFIAADRVTYKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAE2</accession>
    <name>A0AAD5UAE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase mitochondrial F1 complex assembly factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003349</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAE2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
        <property type="entry name" value="ATP11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126:SF0">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
        <property type="entry name" value="CHAPERONE ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06644">
        <property type="entry name" value="ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="34937" checksum="46B216224A307AD7" modified="2024-05-29" version="1">MSKLMIKRFFASIRSVEPKTSLFKPIISVFETNQILESSLKKLSEFDDFNIPNSEKQFDGLNAQNSKTDEFNLQESLKTKKQKQFDSNTTNKKTKYNLKKKNVEKTYFLKKLNKKKKFKSSLELILNNLKNLNSKDGIESMWNQFHDTRRGFLSSSFDSNFFDTLSTRSKSFPTFVIPLRKGGEYDFYFLHFKENRVFYFKLLEPKDKSKACLVVTYFTDLKDSKGVILIQGKIDCDKNNGLQKLKLHEARELINQMQNFYVTGDEKKFKLLEKFNKSFDDFDYQELIAETQQLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBZ6</accession>
    <name>A0AAD5UBZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBZ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="365" mass="42245" checksum="C8E04422F2C94809" modified="2024-05-29" version="1">MKTGDKRPRENSLNLNGSNTFPPTQQFINQSFYTMQQQNKQKKGQQQLVNLKKVKLNEGLANLSFSSLKDNLNEKINITDSNHTQLSKKLNILIEKEKSLCSTLDSIKTERQKLEFEKSKNILLLTNIYDIIEKSLRAARNKKEEVSGKKSKNVYNSSTRRSQRNKRKANVSEEEDDDDSENSDELDDFSKDLFHKLKSGYLCIYHAPPNSPQMASRTIYDICAPLKDWESYTPKLPHILAFLLDRKCENADTVLNNYQINSNDKMILLYTNILSQLNPRVFSKKFYESQGSFTDQKNVDDKYKKIVNLTKKSLILLTSILEKSFNNWLEEICAEKVYNEEKNATLKDDGSSNMEITVNGFFRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS21</accession>
    <name>A0AAD5XS21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001756">
        <property type="protein sequence ID" value="KAJ3201262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS21"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47457:SF1">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47457">
        <property type="entry name" value="OS05G0345500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="495" mass="56512" checksum="3936FA493BABB003" modified="2024-05-29" version="1" fragment="single">MELLNLAKFALQEMLQNFGKRFIFTDGDKINENLCKNSYNIEMLLDLLTDAVKFELTGEYLGDIISTLASRFDEINVLMDLTFFPYEVFLSLISHPEITIDSEYKLYTIISKYIFQKKLQNFQNFNSSTSTINNSSGNDIVTNPNPLKSSTQNLLHNSNSRGNSVQSLFSNNSELNLQCTNNVNNIAVNTCVNNKTDSKFHPYNSINYHPGLTVQQIQDLYSTLNWEKFSIQEFEEAINSNLVPEKILVKGLLRKVKSKEGVPMESIIPRPLTKARKKLNLKSFKFQETFDKNGVVYFLAKQKLLLSNGYLNLEEDDYFNYFNKKNQLNVGTVDFGDGFINPQVNKILKVVMSSILVGNVLNLTSRQKNPTCTRCENGSWISIDFGASIDFKVKSYTLQHGSGGDKFNLRSWVLEGSNDNLNWEIIIKHQDDPTLGGNYGTGSWFTCQELQDENHSQQNPNFSTVNGNFSSYTGNSKFWRWLRIRALGNYFVQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTJ6</accession>
    <name>A0AAD5XTJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000751">
        <property type="protein sequence ID" value="KAJ3213061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTJ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="42587" checksum="41CB86D75B25BFE9" modified="2024-05-29" version="1">MSVETNFAFELHGCFNDNPQNSLFSTLLAPPQNTLYECLKVCDSINSLSLCAFGSFDTLTNSPQCRMADFTSNWDRLGNVSKSNCDQKCSDTNIINVPNGCGKSSTTNPLYSVFTKGNGPSNKAPIPATEKLSQLKVELKGCYSASSDLVTLSKDMTPQDCLAYCNFTNFKFCGIAYGGRICYGSNEVGKKEMKLEECNAVCHYPSVINQNIRCGGLSRDGVRLSVYELGSGSLLKDLSSPTSLETNVPIVTNNIQIEKDIPKSNFSTILITVLVIIALFFLAIGMFLVYRIEKKKKMEKQNRISQLIYPTEFMEGKLPIPIKTVNKVEEEKSNIKLNSMFMFKEAGISTERRKPHAEKREGAGVSLFDSTAPLVVTKNHIAPWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUJ1</accession>
    <name>A0AAD5XUJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001894">
        <property type="protein sequence ID" value="KAJ3200484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUJ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="175" mass="20516" checksum="3057638FA1C54229" modified="2024-05-29" version="1">MQQFVENIHIKSNEAKKKKLSDLEMMRSMQSGLNDSSSSVGQSGGDKQQSFYQSQPETKESLELKQKNQQKAREFAQKELLRKEKESIGSAGEWETVESKEKKVVEEFDDDEDETTLNGLRKKKKDFLFLEKEFKNSDREELEIDLILKDGNKEKEEEKVVFKKKVSKVRNFRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUU6</accession>
    <name>A0AAD5XUU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Heat shock protein 90</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005618</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000447">
        <property type="protein sequence ID" value="KAJ3217025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUU6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="184"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="666"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="678"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="66"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="88"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3217025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="79110" checksum="D2C6AB82D30CF1A2" modified="2024-05-29" version="1" fragment="single">LISNGSDALDKIRFLAITDKEALKHEPELKITIIADKGRKTLTITDTGVGMTKEDLKNNLGVIAKSGTSEFLSSLANDTNPDMGLIGQFGVGFYSVFLVADSVTVISKHNAEDAQHIWESTSEQDFTISVDPRGNTLGRGTQIIIHLKEDATEYLEESTLKALVKKYSEFINFPIYLWTTKTTSEEVPDDSEIDEPLENDDDVEDVDESEKKPKTKTVTTTTEDWEKMNENKPIWNRPAKEITEQEYKEFYQIFAKDTTDPASWIHFKAEGEVDFRGLLFIPAKAPPNFLQKADDVAKNIKLFVRKVFITDELLDFLPRYLSFLKGLIDSDDLPLNVSRETLQHSAMLKLIKKKVIGKAMEMLKKLSKDDDKWESFIKEYGTALKLGIIEDTSNRKKLSKLIRFHTSHVEENGESKMTSLDDYVSRMKKGQPQIYVCTGADLDEIKRSPFTEKLLGRGYEVLYLPDAIDEYVVQSLNEYDGKKLQSIAKAGLKYGDEESTESKNTKEAQAEQFKPLTEFLQTTLSAYVDKVTISNLLTKSPCAIIASEHGITGTMEKLMQNQALGSGDDFMRNYYLKQKKIFEINPDHPVILGLLEKVLNGEEDKVKQITQVLYEATLLRSGYQVSNTMDFAKRIEKVIRQFIGVDLEKEVDESKLKIKKAEEELPEVKKEKVKKLEEEEVIDEEEKKEEFHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV47</accession>
    <name>A0AAD5XV47_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000395">
        <property type="protein sequence ID" value="KAJ3218114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV47"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="205" mass="23568" checksum="D099742A33EF8B07" modified="2024-05-29" version="1">MIAIHHPNLITHHSGSHLNQHMSSIKKSNSSNKNLEFNQNFDWWKAVYPFHQILERYEKKNVQKNFNINQKSSFLQNIDNSKKKCKHDKIRCRECHGFGCPHGRQRSRCKDCGGSEICIHSKVKYHCKECKGSGICEHGKQKLHCRPCILNSTCKHLIKKRDCNECNHKTSVSSMSSQEGGGCIRSGKQHFSNTSRYYSDSSSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVA3</accession>
    <name>A0AAD5XVA3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Meiotic nuclear division protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MND1</name>
        <name evidence="2" type="ORF">HK099_003161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002106">
        <property type="protein sequence ID" value="KAJ3199469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVA3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040453">
        <property type="entry name" value="Mnd1_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03962">
        <property type="entry name" value="Mnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mnd1 HTH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="88" mass="10418" checksum="3E51E94DE55DA14E" modified="2024-05-29" version="1" fragment="single">KDFFQLKDIEKIASKEKGVTLNTVKDILDGLSNYFWNFPSTAYQQKKRLLDESNVEKNKLNLLIKNLTDEYEIHIQGREKSDEREIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVA8</accession>
    <name>A0AAD5XVA8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004892</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000360">
        <property type="protein sequence ID" value="KAJ3218886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVA8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047631">
        <property type="term" value="F:ADP-ribose diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18888">
        <property type="entry name" value="NUDIX_ADPRase_Nudt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000016">
        <property type="entry name" value="ADP-sugar pyrophosphatase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF1">
        <property type="entry name" value="ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="45"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="205" mass="23007" checksum="656204C38B9FA3B0" modified="2024-05-29" version="1">MTKVISKATLNDSDAKWIKLKKITWQDPNGKERLWECAERTTRKGDCDAVAIFSVLTKKSDPNYKPETILVTQYRPPVESFCVELPAGLVDEGESCEEAALRELNEETGYIGKVIKSSKIMVNDPGMTNANMRNVTVEVDLDNANNKKVEPNLQEGEFIELHLVEIDTLLSTLNEFSEKGISVDSRLYNLAEGINYARNFNTSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVI1</accession>
    <name>A0AAD5XVI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001095">
        <property type="protein sequence ID" value="KAJ3206850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVI1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3206850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="292" mass="33325" checksum="25456CA32C3F68FB" modified="2024-05-29" version="1" fragment="single">ANQVTFSENNDKTSLSVTTSIKTQTIEVPANCTLLSSTTPDYSCAPTYNPLLSTTFLIANVEKMQIRVDHSFLVSNNPWFFLPYSYSYNSQSNVAKKIEGRLLYCGLTDNAALNYTLPGTDIFTVQQLMENSFFCEKDYEPDIRKRLTSGAIVSCPILYTTTPESNDDYLTYDYSPFLIERIGILINFSQTGQIGKFDFMTLLVNMTATFTLLRIITVYQRAKFETTEEFGDFELKKKKSNLTDNSSNIEYTDDSFINATSEIHVQNNFLRVEDSVDVKFRRSSIQHNNPEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVK7</accession>
    <name>A0AAD5XVK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001056">
        <property type="protein sequence ID" value="KAJ3207401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVK7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="71" mass="8639" checksum="7C7241958EAB5055" modified="2024-05-29" version="1" fragment="single">EFHNFYNDSFTVLKTVDELPTLFYKIELQFLDSLNWNLPQFNDDLEEWWSLIRNLAHNFLLCLNSSQQQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVN7</accession>
    <name>A0AAD5XVN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Metabotropic GABA-B receptor subtype 3A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GABA-B-R3</name>
        <name evidence="11" type="ORF">HK099_004367</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000304">
        <property type="protein sequence ID" value="KAJ3220432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVN7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="541"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="575"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="605"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="10">
        <location>
            <begin position="389"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3220432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="785" mass="87436" checksum="FE600BBC47B6C8C3" modified="2024-05-29" version="1">MWWTLKVAVDDLNAKNLISGVHFNLLTKPNEGKINVAVQNVVETMTQKSLADSPVVGFVGDSTSAFSIAMSLTSNAFKVLQCSGTATSPELSVKSTHPTFFRTVSPDTYQAPAIAHYIKSVGWKKVAVFASNNAYGLYLGQEFQSVSSTLGIKIKLFYSYDPTNANFTDAAQKIYESGSRIIVIFLRETAKLGMVSSSYVYIGSDGLYTDPPKNTVTNTTDLLNLERIILISPLGISASTVFYSLQEKFLKQFPLSGVTTISSTLSLFYDCVLSIGEAVKDYSNTNSIEDFSSVNMTSPKISLANVKKVNFLGATGNVSFDKNGDPTAALYKIAQFTSRQSTSLHVICIIDGKTGARMENVSQPNFFEDSTKIPSDSPDIFEINLSSTGNLIIFIYFCLSLAINLVSIIYLIIKKNAKAVKATSLFFLFWISIGLTMIWISIVFFINTYTDISCLLQQWVFWIAFGVVFSSLLVKVFRVYKIFSSLRVLTLQTKQLFGFSSLIVLGEIIILATFTILDPPRAVFVELPNMTYYTCYSHNQVHFTTVMIVYNGLLLLLVTLFAYKTRNVYENVRETFWIFQLSSNITLCCSITTLLLFLLNNNNPALIFYIRMTSMAFLATITYGRIVYSVLYIPDKVNEENLTGSALMEILDIDSSHRSDYGSLTQGAKMPSTASLLISLKDSKSLFGKWEKCYLTIYSKHLVIGKFHSNHLVNTGISILCTKDMKIKDIEKITFQIIISDRVFTIECEENAKDKIIGIIGEMISNQKKSGNVLESKELNSNYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW35</accession>
    <name>A0AAD5XW35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase-like protein 7B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">METTL7B</name>
        <name evidence="2" type="ORF">HK099_003699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000245">
        <property type="protein sequence ID" value="KAJ3221194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW35"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF80">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="61"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="281" mass="33117" checksum="EDFFD784A352A204" modified="2024-05-29" version="1">MDLHDIHQPSKQKSLIKDSQIHLQFSNLAKTYDNQVDWDEMMMRLGKRRKDLLNRAKGRVLEISCGTGRNLKYYNKENIEKLYLSDNNKEMLSKTWEKCESLFNKDINNKVIDNEIHVMENDDLKFSDNSFDSVVDTFGLCSCKDPVVTLKEMKRVCKKDGEILLLEHGRANGFFKEFIDKILDKSSIDHATDWGCWWNRDIENLVKEAGLIVKEYHRYNFGTTYYIVCSKDWITIISVTPVVIWLTYGMYERFYLKKPRQVLYDENGDPVIVMTAKHKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWC2</accession>
    <name>A0AAD5XWC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000737">
        <property type="protein sequence ID" value="KAJ3213188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWC2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="21967" checksum="4236EC0C7F2DCDE0" modified="2024-05-29" version="1" fragment="single">FPLKFENIIAEAHYQEKNQLKKGFELALHKEYNHQFATLEKKISDYAVKKNQSKHRRYIRELQYNIRNTLDSLDKYIPYKQEITSEWKVFIKKIQNQFEKRVNDMINNVQQSTTIEKYEKKVLLKNPSQQVANVAATNDKNSSQYDSQIKRSSSGIIINPDSSFLSATTIMIFVNFLITLIKLRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWC7</accession>
    <name>A0AAD5XWC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000222">
        <property type="protein sequence ID" value="KAJ3221571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWC7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026703">
        <property type="entry name" value="ERICH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21520">
        <property type="entry name" value="GLUTAMATE-RICH PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21520:SF2">
        <property type="entry name" value="GLUTAMATE-RICH PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="141" mass="15962" checksum="08F625EFFEA9FACB" modified="2024-05-29" version="1">MLKNFKVSPVSQKLVESKLLHPAFIENKNKFSEEDSAELFLLQQFLGKIAAKQYKEALNLSTDILKLDPKNEVVKEYLILLTKINEEGLLEDEEDEEEEEEDGEEGLSEEDGDDNEENDVSSDSNSSSDEDESETASENEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWP9</accession>
    <name>A0AAD5XWP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000632">
        <property type="protein sequence ID" value="KAJ3214325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWP9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="212"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="336" mass="38660" checksum="D011AC7D75E4DDEC" modified="2024-05-29" version="1" fragment="single">MTKPKMKPKNCKTRGLSALSPSLIQIYSTALDSLGKVKSGTRDISKKQEKPKFKRLETKKEPEVLLEELNQTKLQMHQLTAEKKILLAKIGMLEKGNLYLEKKKEDVLINSALATTTRSLNGPQVFSVSGDNSTLGLKNANTLQNNKIKALEIELEEIKKSIRFTKLVEQEVEIKSYYQETIRLTRLLEHYKSESKIIGGDGEALLEYDACIEEQKNQIETLKASIVSMEDEVKNFNQQKEGYETEIKSLQDQIEEFKQYYTQLAEHCSEKEQEIEKLVASTKEMEEEKVKLSQTILKHQDEIEECNKHSSSQEEQINELNYLQNLHKSENEQLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX25</accession>
    <name>A0AAD5XX25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001286</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001349">
        <property type="protein sequence ID" value="KAJ3204035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX25"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="272" mass="32032" checksum="A356146DA3162AD1" modified="2024-05-29" version="1">MRFAIERKVPRNVEDRLELRKIKKFNEKIESNRNKHYNNKLNDIKRYLQMVKAEMGISDYQNNFSYRSRTPSPIKNNFSYRSRTPSPVKNNFSYRSRTSSPVKNNSDQFPFRVLNFGSPTPSPNCNMYDINYLNYSRSTSPTRSFLLKTPERVNQKYEYLKKNSIMETSPTKFNTNVRSPQKSARTSPIKIAFGSKIPSPIRVKSPNKNRPKSFTKPKYFSREVKFEKAYVPSLLALQDHAKPKSFKDHPKRKQLKLIVERKFRDLAVNSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXG2</accession>
    <name>A0AAD5XXG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRP15-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000119">
        <property type="protein sequence ID" value="KAJ3223733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXG2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012459">
        <property type="entry name" value="Rrp15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13245:SF14">
        <property type="entry name" value="RRP15-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07890">
        <property type="entry name" value="Rrp15p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="33757" checksum="57E076F91E8ACA94" modified="2024-05-29" version="1">MKRKRIQERNNKTGKSTTKKKKQETFKTEEELEELIKNKRDLSDIKKKKNNQKKVTEKDEKSKNIQETDSEKESEVESDFDLNYDDINSNLEDSEDEKNFEDKKIKSDKSSGMTNTIARLLNKDIGLDSKRPILSKLKQIEKKINNEKLEEKAKKLLKSENKILIDKEREINPGKGDPTSVEFEKKLRKISTKGVVKLFNAIRHSQKAIDDVTSVGIQKNSSEVPVVSKSSFLNMIKSQTPNPVGGESIKKNEVDANEENTVSWARDDFLIEKKINNKKNEKKPVSWDNEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXI6</accession>
    <name>A0AAD5XXI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000556</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000113">
        <property type="protein sequence ID" value="KAJ3223895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXI6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004483">
        <property type="entry name" value="SMUBP-2/Hcs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048761">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00376">
        <property type="entry name" value="IGHMBP2 family helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21138">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="205"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3223895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="628" mass="70582" checksum="AE00244F6FAAEC06" modified="2024-05-29" version="1">MDIKEWVEKQRSLINLERETEMEEVKLLNSNFPPSELARKGVAILGLYVAGIRMGLGGKYLVELTAGPGVENIKPHKLKVGDIVSISEVTKKDKVSTVSNDDSGFKISGLIYQIREGKIVLSFKDAVPDELQEKISIFKISNQVTYERIFDTLNKILLKNEDSLTRCLFNFRKPNFCKKNIESLKFFNHRLNPSQKIAIEFALNAEDVALIHGPPGTGKTQCCLEIIQQLCKRGERVLVCGPSNISVDNLECRVKTCDEGKIANDVRNDVEKALKGVSKCKNRKDRRLLYDEIKIFRKELKERERKVVDNLLKGSQVILSTLSGASNKKLLELVKDVGPFDTVLIDEASQALEVECWIPILNSKKLILAGDHLQLPPTIKSRKNEVNNSNYNIEESLEFTLFDRLLKIHGTGIKRMLDTQYRSNEKIMKFSSKTLYDDKLKADISVKNRILTDSQTVTPNDDTTIPLLYIDTMGEMRESEENTSTNNFSIAGSKLNTGEAELVVKHIKSLVDAGVALGDIAVISPYSAQVNLLTLTLRPLYNDSKELEIGTVDGFQGREKSCIILSLVRSNENGEVGFLSDERRLNVAITRAKAHLCIIGDSETLTRSGGYLKRFVEFLEEEGEVRYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXR0</accession>
    <name>A0AAD5XXR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Polysaccharide biosynthesis domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001020">
        <property type="protein sequence ID" value="KAJ3207962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXR0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045492">
        <property type="term" value="P:xylan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006514">
        <property type="entry name" value="IRX15/GXM/AGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31444">
        <property type="entry name" value="OS11G0490100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21729">
        <property type="entry name" value="IRX15_IRX15L_GXM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3207962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="19617" checksum="8D4D3F827813C0E7" modified="2024-05-29" version="1" fragment="single">CKTNKYGKTNFFENQENLILKYTEQVFEYLPKESSEVNLIPVQYFGKVSQQMEFFSKPWLLDVPDIVKNDCYDVVLIDGPSGFLPDDPGRMEAAYFSVETAKRCILENKLDSVYIFLHDVERDLERTIIDRFFWEGELSVKVEGEWGELTGWKFNRDTLSLKNNYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXW9</accession>
    <name>A0AAD5XXW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000941">
        <property type="protein sequence ID" value="KAJ3209441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXW9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3209441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="383" mass="43808" checksum="9C4EF1C49085EB55" modified="2024-05-29" version="1">MAEMTVFIKNPDPFFQSNMNSAILAASIDVLDFLLANVILYNTLKKNHRKKKFNNLMLIAALAWWLFTLTSLVTDAAAIIFGVNLWVFPNRHPVWIMFLVRFLTYYGSIMCYQLLTIHRFSKLVQNIRPYPKFVDYLLILIAVLINSLFVLPALFDYLCALLDDHWWLDDNVGFCNNLIITTPYPTYGEFYSLELLGALIQVFGIPIFETLLGFSLLLIVIKVDKISKIFKKASKGYDVQSIKIKKIKKEIKVFCIVWLCVVWVAGIINIIAQSNWVIYLFSDDDVMNFNYYGFFNSFGNLLVGVEFAFYFQFMEKLTALATVGREKLGEKEKNGSFCSVSQDDKASRTSQVDVSKRKTKTMMDSKSDIPGLTGSEAAEESFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY77</accession>
    <name>A0AAD5XY77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000811">
        <property type="protein sequence ID" value="KAJ3211831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY77"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="1">
        <location>
            <begin position="5"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="395" mass="44217" checksum="A9B4AD2A1B98831B" modified="2024-05-29" version="1">MSARKKLIVYHTNWSMYGRNYHVSNLPIDKITDINYAFLDLKQSDAYENFFVPTLSDPWSDVDKRYTDDTSVPPPDTWNDDNCFPFGNFGQFVKLKKLGKKFNFGISIGGWTFSKYFSSAVSSEASRKKFVDAVVDLIKKFSLINRVDLDWEYISPPGKNYGLEGNIVGEGDGYNFGLLLQELRNRLNQSFGENYIEISACVTSDPSKISALPLKEMSLYLDTINIMTYDFNSSAWGPVLAGHQTNLYPSLPYAPLSVTGAVEAYIKSGIVPSKIVIGVAFYSRGFANTEGLGKPSNGVVEDMSWEQGVCDYKSLPRPGSTEYWDSIAHATYSYDPVKKILNSYDSVDSIKAKCEYVWEKGLAGIIVWESSGDVMDVNDSRSLFRALNEGLASRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYV0</accession>
    <name>A0AAD5XYV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Costars domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the costars family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYV0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032970">
        <property type="term" value="P:regulation of actin filament-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1540:FF:000002">
        <property type="entry name" value="costars family protein ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1540">
        <property type="entry name" value="Costar domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044302">
        <property type="entry name" value="Costars"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027817">
        <property type="entry name" value="Costars_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038095">
        <property type="entry name" value="Costars_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46334">
        <property type="entry name" value="COSTARS FAMILY PROTEIN ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46334:SF1">
        <property type="entry name" value="COSTARS FAMILY PROTEIN ABRACL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14705">
        <property type="entry name" value="Costars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01283">
        <property type="entry name" value="Costars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Costars" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="83" mass="9310" checksum="0AEFEFBCECB5F013" modified="2024-05-29" version="1">MNVDHEVTLLIKEIQRLGEKDSTGRYVVKFGVLALDDHCAQIFEAIVGTLKAAKKKKVVDFKAEILLHPTHKDVDIVLLKDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYW2</accession>
    <name>A0AAD5XYW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000222">
        <property type="protein sequence ID" value="KAJ3221570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYW2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="320"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="470"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="655"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="839" mass="96449" checksum="916D4FAF721EB46C" modified="2024-05-29" version="1">MEVDERSEKLAAAKKKKDTKTNNLANKIEVLEVDFSAKPKNEKLKTYSNELQRFDQGLVTVATTPAKSIISHNNPKMLLEPENEILFLRSQIESQKQAIDLLIDEKSDMQHLQDKIYEKLQQQVNFNKENTESIENYKNLINNLENKVDDLVIELNASNCRVDKFNSEVNTINEMKNQKAVLLEKCRLLSEANNKLESELLNLRNNQSIVSQSPQINYDITANNFNPTVEKLMSTVEKLNSTIADQGNKLETAYLEISDLREKLSIEEGRNTVLAEELLEMQRDKTVKFDTNNQLSTRLMDYEGKLIHVSQENFDLKAENDKLKVDLENSTLNLNTVNEKLLTLENLRSTWLAELEEKKKLNALVSSSNDKLAKLQSENNEMINGLEELRERHIIIVEEKLGITEENEKLKGKIKMLILEVEALEIYKDEIQRLKEMIRNYVEGSASARLSISDPLKKPLELETSECKSLESLQSELQLVRRESEVIIDKWRNSEDKYVSAEKRADELENKLRLSICERDSVKKDFETGESLKVELNETKEKLKILDVKLLQTLEENSKCKNEVELIKAIWKHEKDNWGLEKLKLEKVISDFDVKSRGQNALNGIASTSDTDNYLRVMPNITKAEPVLSKETSPIKSSPVSASAVVPDSVILTELENLKTLNLTLLEKLTNLQEENRKISDLLENEKKLNVLLTAEVDSLPDYIFMYHQERKALLAQMQKMVLKIQREANLKLMMEKKKLNSSLIWSSKVFDSPSNKKLVKDLTSNDGMKSDIISFEDKKINNSLQEVTETKLNKEKVQEVFREKGKFFGGGMCLRGYVDEVLPCKNLYSISNTYFKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYZ3</accession>
    <name>A0AAD5XYZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYZ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019384">
        <property type="entry name" value="FHIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705:SF11">
        <property type="entry name" value="FHIP FAMILY PROTEIN CG3558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21705">
        <property type="entry name" value="RAI16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="789" mass="92830" checksum="F97A3DF71AF297B2" modified="2024-05-29" version="1">MFMIKGLSNLVSSTVEVLSPTIKTKTEAFRDHWAYIKHFYTVREDNLDHEKIEWINYTNIPYHLKSMLKYLIVEDIDDSSIVENFQVNSCFEFLLEENAFEFLVEKFELDNPIGVNIQVLKFFITILNNLLIANNVEEDHNSLEFNASNFLPESKFLKPLLKLLSLCSLINCGTNNLNQNYLQTPQDDVVSEGEEDFEDDDEKLNVSLKILNLNLINLLTKIVIKSPFLINLFYYDNSNFQKEENKLLKTVKSREIFEKQEEKKKKVFLLLDLILEDLFEIEEFEVGEFSRLILLDLISLIKDENLEKFLTDDERNYKTLVHKMREIYFKEQLNLIIEKNNNNLTLPIKLSKISKIRYILNLNDKNIIENEIADEKNNSLENNYADENFNNFKKLFFVMWEYVEKLLDCGSMDLKEKLETELKKFFEILFKELEDTKFPEKIKFSLQILIEFVKKTKNPKTLDFLLSLILYNKKFDVFDQIFLLAFDYELNYNVSVFALGLLNNIFSLFHDKVIIKLTDGIEELEMERDKKHITISNQDCRTKNLIKDILSIIGDKDPLLFTDSVDKFDDYFFEAFESIEYYKKIKLKESATSSSFSKESNYKECHEYGLKKSEKFYFLNKFLSNFQKIESKKIGWNVLFVSCFRTLSIFDNPVLENCLFFEKNDNKESMEKKLNLVNVLKNLVGNLLVSTSNLPDSKNNLNLTPKGESFIENIEENVKNQKILNHQDSKISLDLSNSLDEDNERLIGSSLQKEEDDKYLAYLVTVEFCKEISSILLLKGWKGEEIIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ79</accession>
    <name>A0AAD5XZ79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ras- protein Rab-2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RAB2A</name>
        <name evidence="2" type="ORF">HK099_005019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000376">
        <property type="protein sequence ID" value="KAJ3218524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ79"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="206" mass="23514" checksum="49DD7F0197C56C41" modified="2024-05-29" version="1">MSQQYDYLFKYISVGDSGVGKSCLLLRFTNQEYTATETTIGIEFGSSIVDLRNKRIKLQIWDTAGQERSYWMFIITRRESFMHVKNWLEDVMTHGHEEIKIILVANKSDLDSVRQVSTEEGADFAKKHNMIYLETSARQGQNVDQAFTKLAENIFDTFNLSRNVSEISDSEIRNMEIHGVKFGPQKPALSILPNNQSNNQQSGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ92</accession>
    <name>A0AAD5XZ92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006156</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000513">
        <property type="protein sequence ID" value="KAJ3215888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ92"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="599" mass="65742" checksum="3B29B0912AA223A8" modified="2024-05-29" version="1">MTEKQERQQWPSRAAFLMASIGSAIGLGNLLRYPSVAWANYGVQWFIPYILALFLVGIPLLLLEIAMGQTYRSSNIVALDIVATYYNTIIAWCLIYLGNSFQEPLPWKGLPGQGADAAKAFFSDVVVRNVSASQGQVIWLTFAMCVIMWIFVYLSIFKGVDLLGKVVYFTMGVPTVMLVVIVIRGVTLENAWRGMQFYIGTARFETLGQTDIWQGAIGQIFFSIGAGFGVFTAYASYNPLMSHAVSDSLIVGISNSIYEIVAGFAAFGVAGFLNLDPAKDKLGTFTLGFFTYPAALANLPGAQVWSVIFFFTLFLLGIDSAFSLVEGLVTLLEDSRLSKKLSRPVITGLVCGAGVIISLMYSSDVGLEFLDQVDRYTNEFALPMVAFIECVAIGFVYRWKDAVGQVGATAFLINFVGYNAALLFGCIVAYVSNFGFGILIGFAIFFVTIAISVFSAKNPTVSQHSSPVLNKLYWLNLYNGDQLRKDLNAVVATHGRWEIPLTWVIIMKFLTGPICFIMTTLPFKGVAEAKFIANPIAVFGFFVGMLTLIFSLIGLVFPQAYGFMLPEDSSLLWKEQNEAGPGITIKPTILNETLEVEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0A1</accession>
    <name>A0AAD5Y0A1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 8</fullName>
            <ecNumber evidence="3">2.7.11.22</ecNumber>
            <ecNumber evidence="2">2.7.11.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SSN3</name>
        <name evidence="15" type="ORF">HK099_008456</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="3"/>
    <dbReference type="EC" id="2.7.11.23" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0A1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="28"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3224436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="350" mass="40629" checksum="C460C72DCC5CF018" modified="2024-05-29" version="1">MDSTSQIEKYKLFKASKDNLRKTIYQRYTILGYIAAGTYGRVYKAESKVKNSNNNEKVKEFAIKKFKPDKEGEGNLSTGLSQSACREISLCIELKNENVVHLEEVLLGPSDRSIYMVFEYAEHDLLQILLHHSQMGHGFPIPDFSIKSFLWQLLNGVSYLHLNWVLHRDLKPANILVTSDGVVKIADLGLARLFHKPLQPLYNGDKLIVTIWYRSIELLLGTRHYTKAIEERWPNLEYMPDYKELQAMPNQNYPYGLHEFIYKRFSSKNSSLIDLISLMFEYDPVKRITAEDALKHQYFLEDPKPSMNAFCQFDTKTFNYPMRTMQQDVDEKSGGMTSNIGNDNKRIKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0W9</accession>
    <name>A0AAD5Y0W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cilia- and flagella-associated protein 69 ARM repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0W9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902093">
        <property type="term" value="P:positive regulation of flagellated sperm motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048732">
        <property type="entry name" value="CFA69"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048733">
        <property type="entry name" value="CFA69_ARM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14716">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14716:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21049">
        <property type="entry name" value="CFA69_ARM_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cilia- and flagella-associated protein 69 ARM repeats" evidence="1">
        <location>
            <begin position="161"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="38040" checksum="FA1B81773D6797E3" modified="2024-05-29" version="1">MDSDFLEFILMYTTYQSVKESVKIWNLRQLKGLQLQIIFLLNSIISNTKKMQKYLLNTSKCEKFMEKCFINLENLNTLLQQFLKNETVVGLIKFLSLTMQYETNVIEFGKNNVESEVIGLIPAVLRSVLLLSEVSLEAQVKLGNFGVFDPVFELLNDKTQTSEVWKISLLICSSVCKNCEENKVLFGNAEGVNTVISFLNYKSPDIKEEESVLLSVTECIWSAICGNHKNEESFFHLNGIYDLLDLLEIKTSDLRKHLLSCLLDLTEIPKTSFMIMEWRRKTKGKTHQGIEHYLIELWNFEEKHIEISQGDHGVLNNFYSPLIGKNNNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0Z4</accession>
    <name>A0AAD5Y0Z4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000050">
        <property type="protein sequence ID" value="KAJ3225868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0Z4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052514">
        <property type="entry name" value="SAM-dependent_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203">
        <property type="entry name" value="METHYLTRANSFERASE, FKBM FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203:SF15">
        <property type="entry name" value="SLL1173 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041959388" description="Methyltransferase FkbM domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="135"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="38392" checksum="F16CF81F5E7259E4" modified="2024-05-29" version="1">MVSLIAVLLYIQSSHADIPKNFKAKSSFNKLANINYSPTRYATETKNNKFGSEENYQPYYYELPECSLGFKTRSVVVTAFTRPYRNYLHNYGEDVHVSESIFGNAATGLLFEHHVREKMFKMLGHFNLKHPVIVDIGANIGLHALYFASLGYEVHAFEPFKKNADLISCSIAANQFHNVKFNRVGLSEEDSTMCMDVPDNTNHGHAVVNTNANCNNPLEFIRFDHYLTNIMKGRVPDLIKIDIEGHEYKALITAKEIFKKKKPKLIFSEFNPLFMKEQNIDPKDYLKFLIEIGYNVYTMGLIQINLDTDLLNPALALWDIIAIDKDFDSYEIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y112</accession>
    <name>A0AAD5Y112_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000213">
        <property type="protein sequence ID" value="KAJ3221720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y112"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="124" mass="14401" checksum="F5871D160791F145" modified="2024-05-29" version="1">MYSAFDDDAPYQSFTVMPGSEKISDEVFYMDGDAFETDNNEKKESYSSPNRTKKIKKELFNESSSSRDTKEKNSEGESNQVVYDNQLERNYFEKKSIIVKIQFLESSCGCFKSENAFDRIIKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1W8</accession>
    <name>A0AAD5Y1W8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Serine/threonine protein kinase, CMGC, CDC2/CDK sub</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">BUR1</name>
        <name evidence="16" type="ORF">HK099_007300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1W8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000415">
        <property type="entry name" value="CMGC/CDK/CRK7 protein kinase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000124">
        <property type="entry name" value="Cyclin-dependent kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF233">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="97"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="402"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="414"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3228019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="462" mass="53200" checksum="CAB8751FDA383EC5" modified="2024-05-29" version="1">MSNNEIESSTSNEKKRKRVKEEEEEEELGEISPDGSYFSPPMAPRHPSQNDPLSQTFTEEDLPLTPNTVTSPPPPSGQENNLISSRSFKGCSKFDDYEPIKKIGEGTFGEVSTAKHKPTGRTFALKKILMHNEKEGMPITALREIRILKALKHPNVISLFEIAFQKGDRQIRRRGSIYMVFPYMDHDLSGLLDNKNVRITAAQIKSYFQQLLRAVEYLHSCNILHRDMKTSNILIDNQGNLKLADFGLARDFERDNKEREYTNMVVTRWYRPPELFMGAVKYDESVDMWGVGCVFGELLKRRPILTGQSDIDQLEKIFMLCGTPTMADWPEHINLPAYKSTISAIKSSYSKSFSERFSSLHKEEANLLELFLEMNPLKRISAKKALEHEYFITYPLPAQPGSKDFSPFPTSHEYQTRQERHKAEAEAEAKRASTTRNDGNWRGKDRREYDGRWKDERDSRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y284</accession>
    <name>A0AAD5Y284_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000107">
        <property type="protein sequence ID" value="KAJ3224050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y284"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="53" mass="6048" checksum="BD8D80602B6A625B" modified="2024-05-29" version="1" fragment="single">AIGQPLKREWKIPVKPQIPRSYPSKHLNSEYLIFILVPAGSRDLNLSGYDDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2V7</accession>
    <name>A0AAD5Y2V7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">T-complex-associated testis-expressed protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TCTE1</name>
        <name evidence="5" type="ORF">HK099_007038</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2V7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052410">
        <property type="entry name" value="DRC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107:SF2">
        <property type="entry name" value="NLR FAMILY CARD DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107">
        <property type="entry name" value="YNEIN REGULATORY COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="556"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="620" mass="68630" checksum="20520D65DC48CD26" modified="2024-05-29" version="1">MSTVSISVPTKEPLQGKEASSPNNTVPATPVGKEPQTNVELEIKENESANTGNHEVTFGSNNEVNNNIVGGGFISSKDNFVERRMNQRKIIGEDPEWNLAPVKKLTALCIKVIVKNFEKNPIIDGIPLKYRKSVLSEISTSLPLSITANLIPDDLYWKKCAQEKFINCDPKRHGGSWKRLFFERYCKHLIEYYQPNSRVTEDINVLELKPLEINQKKSLQALQQQNHVIYTTSANSHQHQIEKNAIKSLIFTDTNRFLSELKLASPFVKTLELDQLRPKEPAEASVIKATDAPPDHLDLNVVFGNLLNIENISLYYGVRDCGINFNWLLFGMTITDCLNLSQSLKLKHVAKNLKYLKIESSSIDDDRCRLISNALLDNEALSSLDLSHNKICDSGARGLAAVLASPKTNLNSLILANNMISFRGAHAIGKALASLNTETKVQKLPINGLNISNNEKKPEFGENSQLKVLNLRLNRLGDEGGEELLNLLLKNNFLTTLDLSGNNLGQKSIKSLCTLIRKNCPKLRRIDISCNKLGSRGGEKINQIINNLSGVVEKGNNTNSRVNSAGTQSSSGDSGQIEPDAAGKSLFEAISHNKYISTLDLRITEIPSEYVVAIQGIVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y343</accession>
    <name>A0AAD5Y343_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">tRNA pseudouridine synthase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PUS1</name>
        <name evidence="9" type="ORF">HK099_006122</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a uridine in tRNA = a pseudouridine in tRNA</text>
            <dbReference type="Rhea" id="RHEA:54572"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13934"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000051">
        <property type="protein sequence ID" value="KAJ3225824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y343"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02568">
        <property type="entry name" value="PseudoU_synth_PUS1_PUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.580:FF:000002">
        <property type="entry name" value="tRNA pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041708">
        <property type="entry name" value="PUS1/PUS2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF4">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="8">
        <location>
            <begin position="304"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR641708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR641708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="510" mass="58902" checksum="B05CA9F908B899E7" modified="2024-05-29" version="1">MSELESLEEIKTKTLPINPEEKEAKGLLEEEGKKNKEENLILGKNISNESLKKGNDVKKKNDFFVKGKKRKNKDNEDVETKKKIKYNGQKVKEWTKRESDGEEKEEKKPKKKVALLMGYCGTGYQGMQINPNAESIENELHKALAASGAVSKDNAMAPHKIGFMRAARTDKGVHAAGQVCSLKMIVEDEDVIKKINENLPKQIRVYGYVPTTGGFHAKFQCDSRIYEYLMPTYVLQQSNPALFPYSAIAEGLEIDLESNQPIYNEKSGQYIFKNSSPITAEEMIEKRKFRVSEEILEELRVILKCYKGTFNFHNFTIGKAFKEKNANRFIKSFECSKPFIRQNSEWVSLKVHGQSFMLHQIRKMVGLAIMIIRTKTPHKIITNLFKDVKVNTPKAPSLGLLLEQAIFEAYNNKLKGVTKSDKRPVNFEKYKEEMNTLKEEWIYSKIINEELETNEFEKWIRIIESHSMEFSWWLKKDGEIDLKLKPASLKEMGRGLLEKEEEEEEDVEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3X6</accession>
    <name>A0AAD5Y3X6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3X6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018810">
        <property type="entry name" value="UPF0662"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086:SF1">
        <property type="entry name" value="CU(2+) SUPPRESSING AND BLEOMYCIN SENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086">
        <property type="entry name" value="UPF0662 PROTEIN YPL260W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10303">
        <property type="entry name" value="DUF2408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="469" mass="52921" checksum="D1B742FB8EB0FECF" modified="2024-05-29" version="1">MVITASTTRNNQDLQSLYQLQHDIREVVKGKTPKLNDIQELGERTFKANILYENTLAKLEREKRKLESVMKHIWDGFDRAVLPLWKVDDELISVYDDLVTVMRSLEELNSQKDPLPSNSSKLLKLQEELHIIENDHCVNGLYVPLGWKRNDRIPTGQSILALLFSRNYKLVRHIQEKEPTVSSKLIPLELRLRNIVHNLQMIKDNYTDPFEDEFGPIPIDQIEIGVLQEQLSAIENLQVDGKFVDDDGSVPSGQGTLHSLLEEGYDLVHDCLIAAENKATSENDLLNGAINQARHVADSIFNNASRVTKDMATEARSVSLTTLHTLQATLEQGSDILKKVVVNPADSLKSTSKVLASSTRGALGFLNKLYGEFEPVDPSLLHTYAAIKKIRNDLKLLRNEIDLIKLRPNNKVDEVNLNKRLRILQEELDIIDGQKVDGKFLNSDGDIPRGQALLSSLLDESYCLIAEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSY1</accession>
    <name>A0AAD5TSY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002021">
        <property type="protein sequence ID" value="KAJ3199861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSY1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.240">
        <property type="entry name" value="Transglutaminase elicitor, body domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032048">
        <property type="entry name" value="TGase_elicitor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16683">
        <property type="entry name" value="TGase_elicitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="21597" checksum="7E177370966FD8B0" modified="2024-05-29" version="1" fragment="single">YYPVFRDAINDISRNETKSPSEKYAKAFNLSKKKLFNQISKKSGVDSQSSRDPCETDNECNWTGLKEKCAIRRGRKSGYCIPAWFGICHAWAPAAILEKEPKCPVIVNGVEFKPKDLKALITQIYDGAEIDSIEYGERCDLQNPLKDEFGRYIRPECRDVSPDSFHIAITNVMGTLDKAFVADMTATAEVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTA4</accession>
    <name>A0AAD5TTA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001602">
        <property type="protein sequence ID" value="KAJ3202234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTA4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="364"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="172"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="454"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="560" mass="64745" checksum="B5E37A6C83D4B019" modified="2024-05-29" version="1" fragment="single">MSSPVVQANLESHSKAVEASVNSGGGVPANKTLEQATTLNKKSSKQKPAPDAVTPAVNNQYSDFKEQRLAELVEKLQSEAVVKDLLAESQKIEEQIFLGENEVFHKNEEAFFMVQDENETLCLKTLHNEDVKALKALHEQQVQDVLKRKAAKRFQRQQQREVKALYNKTHEQDIAYKKIEEVKKKLAEHRERTEKLIDHIEERHVKQIKQFNAAEARRIADQKLLVELKVAHLTEEQKIAAIKENQSKINHQKALDKKKLDQIREQQRRELRHLKEEFSNMNSTQILEEQDMINKHKLDYLLEKEKITATESSIKVIKLQAENQIELTKLINQQKQQLRQLRRAQKTRKAKRFKHWSAIIQRDLLKKNGGDQRSTNASNFQSSDASQSSSVGSHSLPESQTLTRQSSDKNLNKNLPLKNNLDLLGEEDEEDDTQSVVSLDTQQQNAEEKLQTMVKGLIELKNSQEEELEKLRKKIKEEKQAKEEEFQKLMMELDWQKDVNLKDLKIADEAEINEAITVQERELEMESHIRQAEVKALMERKVLKNLLDSVVDGVISIDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUA7</accession>
    <name>A0AAD5TUA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N(Alpha)-acetyltransferase 20, NatB catalytic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NAA20</name>
        <name evidence="5" type="ORF">HK099_000888</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001221">
        <property type="protein sequence ID" value="KAJ3205247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUA7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000034">
        <property type="entry name" value="N-alpha-acetyltransferase 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3205247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="176" mass="20655" checksum="A4846BE41BCFC748" modified="2024-05-29" version="1">MTTFRPFQCSDLFKFSNINLDPLTETYNISFYLSYLAKWPDYFSMAVAPSGTPMGYIMGKAEGENELWHGHVTAVTVALEYRRLGLAKNLMRILEEVSEKIYDAYFVDLFVRKSNLLAIGMYEKFGYVAYRRVLDYYSGENGEDAYDMRKALKRDKHKKSMIPLKRPIRPEELEWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUF2</accession>
    <name>A0AAD5TUF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000724</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NCF2/NOXA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001180">
        <property type="protein sequence ID" value="KAJ3205731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUF2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000017">
        <property type="entry name" value="NADPH oxidase regulator NoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051864">
        <property type="entry name" value="NCF2_NOXA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15175">
        <property type="entry name" value="NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15175:SF0">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN C23A1.17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="6 7" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="9">
        <location>
            <begin position="369"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="287"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="287"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3205731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="456" mass="51212" checksum="4DC04B3DB38C4DCB" modified="2024-05-29" version="1">MSTKEEITLWSEGVKFCFNGDFNSALDKFEQIRDFSKVSFNIGLIHQKLNDHLTALDFFDSSINKDPYLAAAYQQRAYSLFLEEQYELALEDYTIAIELMLENSQIDYTQLGMNYVLYKAEVLFNRAMCHSQLGNEQKSLEDIRDAQKCVVTDDQKDIISSAARLGSFEITLFSVPPDVMFSISESKLKNLKEKKFLKDAKVVAGADDTYDGFSGAAILKKETVSRKDSATEFQSKTEKNLLSLGQSKSLRYPSPPPDNNNIQRSFTEPQISRSFTKANKVHVSQFSGSGKVGVRGSSISVQQRRPSAPESRSASPAGFLRRPSAPENNSSISTKPTWNKAALKNKELDEMSESSFGNNSSASSGGGSKIKFKVSYNRELYTILYPDEPINFSYFTEKVEKKLKLKGAAFRLLYKDEDGEMIVVGDEDDLDICRESNSILIVNVTSDQEAELYDMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUX2</accession>
    <name>A0AAD5TUX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001047">
        <property type="protein sequence ID" value="KAJ3207566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUX2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="305" mass="35046" checksum="63ED891A01DCEE00" modified="2024-05-29" version="1">MGSKTNKKRKLEKENTTETSTVELNLTSEVINKNNTSKSNGTPKEIEKQPVSEKVQKKKKIKNIEKITSTEATGKLESNDEILFKKKKKRKLSKDQSTDVKSHKHHSINSVFHESIKENTTILNDNDTSSFDENLITAQFLHTTTEQAKVSDKGETKKNNIFIEDKTVVNVDLKSLISGEQSSFSLFGNLNNQLKSDSILEKVSANRNVDERDNANEQNVDFAKEQEILQSFSTSKFFFFHLNSSDKIKERSIYSEDLEKQVFKRTKDLDGINETWEKNKKELTYDFKSKHKAALKKLTKMKRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUZ9</accession>
    <name>A0AAD5TUZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001963">
        <property type="protein sequence ID" value="KAJ3200140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="88" mass="9949" checksum="CBEBA4674D05CC41" modified="2024-05-29" version="1" fragment="single">MPEIWFQLVDSEGNPYNKTSPSTILVQQDTNINVLRKLIKVECSNNLSHIDAVDLKIYESVAKLRDNSPINPKTLVLKLDNTEDLVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV41</accession>
    <name>A0AAD5TV41_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001006">
        <property type="protein sequence ID" value="KAJ3208223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV41"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031991">
        <property type="term" value="P:regulation of actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051492">
        <property type="entry name" value="Dynamin-Rho_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN FUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834:SF20">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="183"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="388" mass="44167" checksum="C81376308882D55C" modified="2024-05-29" version="1">MQNETEIKLKQGENLSFKEKLKLFENSTSTSKSSKESKFQLQQVEINSSTTPHNPTNNFKTSPPKPNKPPKPSHLKAINISDTYLHTESNFNYESTRNFNNDPNVLGETVSESAFSNTVKLFNDSNATFNIFQATISTVIPKNSSQVSTLTLKKPPPIPTRPSSQWKKRGSKVEETSNKMLSNRQKVVMELLETEQSFYKDICLLKEIYWISALEEKIFSKTDFKLLFSNLSQVVATSNKILENLVVVSNDNGLIGKLFNEMFDEIQETFCEYCKNSEQSLQKVSEISSPEAPDNVKEYLKTCQLKLHGKTFAWDLPSLLIKPVQRVLKYPLLLKQLLKETDQSHDDYENLTIAVKRSEAVAEAINTVKKRKDVVEKYTTGKSNLNVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVB1</accession>
    <name>A0AAD5TVB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001096">
        <property type="protein sequence ID" value="KAJ3206832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVB1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF13">
        <property type="entry name" value="OS03G0201400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3206832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="622" mass="73957" checksum="2534DAF5FFBC8922" modified="2024-05-29" version="1" fragment="single">NIQKRKVNSIFHSEYLYLQMMKHQLNSYPINFKVFYELRRRYQLMYNTSVMNTDYLILMSTAYGKQLDSDSLNVLWNTVKSAGIEVPKELYQSLIQAYSNLNDINGLSSVLYSSKVDQLEDDKIKYAKLLFPIPSNDPVVYESLMNFYLKMDQIDVVLHLFRDFTLKCNMPNKLDRNLMKIYLIVVKAIFSDLPAKLAHQVFRSIKKRTLPESRDLVYQYFIQFFSESEDVHMAEKILMEAIDKNVAVDCSAIIPLVSAYLEKEDMKNALKVLEIWMKANFRQNEYKPTTFEFLYKLYLKNLFFTAESDYQKREHILNCFKKFNRSISTINTGNELLLKEYCNAGNIVMAVKLLQTLQNDPRSYLPIRNPVSNLNAPLLSSVILEAYYTTINFFCQRKLHLSALKLIQQLYLLGNQEEHRNSFSFKKKLQLHPKVFLALFSLLEKMNDVEYCLKLIISMLNVNLIPDLESFEHIFRLYLMQYPVENFKNFKKNSKDLHYSDKIYLKEVLNLIEFENGRFKKFKELLKFRVFNSILSFYLKKIKNLKKLNLNYSTDLKYLEIVFFEMNTENVIVEKHLMKILKKEFKTDLKYNRHVYYYKFTGSHSIFSDGNFVPYQEFIYPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVD1</accession>
    <name>A0AAD5TVD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquinol-cytochrome c chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000922">
        <property type="protein sequence ID" value="KAJ3209800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVD1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021150">
        <property type="entry name" value="Ubiq_cyt_c_chap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007129">
        <property type="entry name" value="Ubiqinol_cyt_c_chaperone_CPB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184:SF1">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03981">
        <property type="entry name" value="Ubiq_cyt_C_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="2">
        <location>
            <begin position="28"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3209800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="174" mass="19906" checksum="E12495A37D5D4BE8" modified="2024-05-29" version="1">MSRIDDARVAYQSCSDQIEIKSNFFVDELNLIDNFQTWFSITVLHMWILNARLRQEGPAGKEMRQELFNHLWLDVEIQLDKAGARKNVGTLIKGLIDGYYGQTLAYDEGLAKGDAVLASALYRNVFRANVNSDNKFVNLVELGKLTEYVRLQLQNLENSVRADVLTSRTKFLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVR4</accession>
    <name>A0AAD5TVR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000940">
        <property type="protein sequence ID" value="KAJ3209463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVR4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042289860" evidence="2">
        <location>
            <begin position="21"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3209463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="174" mass="19052" checksum="6DDB33995E09A125" modified="2024-05-29" version="1">MKLFIYLIFLSIFQIYVVKAQSTATTEEDERLNSRISRHDERVSQRQAERATRKSDRIATRTQRNSLNPSATITEKLPLPTNTETTTANSLTTITPTVQGVIGPDGILTTAFLGGDGSITQLRPGETIPPTARPIPSSTISPTTIPSNPSKNSAANSFQHFTTIVILFLLNLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWI9</accession>
    <name>A0AAD5TWI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome regulatory subunit rpn6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPN6</name>
        <name evidence="4" type="ORF">HK099_000569</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001130">
        <property type="protein sequence ID" value="KAJ3206363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWI9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000007">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040780">
        <property type="entry name" value="Rpn6_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18503">
        <property type="entry name" value="RPN6_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="219"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3206363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="417" mass="46565" checksum="709E92C42DD666C4" modified="2024-05-29" version="1">MAAPKLAEAEALAKTAPAKAAALYEQILSTVTGKSDEEIKVRETSILNLGSIYQKEANKDALAALIRNSRTFLVSIPKAKTAKIVKQLIDLFTEIPNSLNLQVDICKESIEWATTEKRVFLKQSLETRLAALYLENKLYTEALSLINVLIKELKRLDDKNVLMEVQLLESRVFHSLRNLPKSRAALTSARTSANSIYCPPLMQAGLDMQSGVLHAEEKDYKTAYSYFYETLEGYNSQDDRRAVSALKYMLLCKIMLNLAEDVHAIVNGKIALRYAGSEVEAMRAVANAHQNRSLIEFESAISKYKEELGNDPIIRSHLTALYDTLLEQNLLRIIEPFSRVEISHVASLVKLPTAQVEQKLSQMILDNVFDGVLDQGVGCLIVFEEVKTDKTYEAALETIKSMGNVVESLYQKAALLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWL0</accession>
    <name>A0AAD5TWL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase M43 pregnancy-associated plasma-A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007663</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M43B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000763">
        <property type="protein sequence ID" value="KAJ3212804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWL0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042059810" description="Peptidase M43 pregnancy-associated plasma-A domain-containing protein" evidence="9">
        <location>
            <begin position="25"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="10">
        <location>
            <begin position="151"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3212804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="280" mass="30341" checksum="6E1C1039236317D2" modified="2024-05-29" version="1">MKFGLYTTIISALALICCSKPSEPEVVCGTRELNITKDAAVSQFFNLQNSFLSALPSTVYINVYIHVIKSTSGAADVTTSQINQQMDVLNAAFAASGFQFTLLSSTEVVNPSWYTVAYGSSEESLRKRALRRRTAKDLNMYFANIGGDLLGWATLPNEYSSDPKNDGVVILSQTVPGGSETNFNRGDTATHEVGHWLGLYHTFQGGCNENGGDFVLDTPAERTAASGCPTGRNTCTGAAFPGNDPINNYMDYTYDTCMSQFTPGQATRMKSLWGSYRAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWN9</accession>
    <name>A0AAD5TWN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multiple epidermal growth factor-like domains protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MEGF8</name>
        <name evidence="3" type="ORF">HK099_001592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001463">
        <property type="protein sequence ID" value="KAJ3203185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWN9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3203185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="462" mass="50740" checksum="DFA159E341689622" modified="2024-05-29" version="1" fragment="single">MNLTTKANVDVVADTGLLEEIVLASKRNIKVIGANVDLSIVDDNSFIGKGGNVSAVLTSVLKNLDVASSKAIYDALNNAVVNESVVIDAAYGAVTLLPCFKDLCYLFEKEVDKSVTVDGCLKKVTISVQRYIEEIFIKVKGGIVEAGVDYKTSFLSELLVAENNTFHLSIPFGSRPPALQKHTLTLDIQKLNTYFYLFGGTDKSASLNNDLWVLDYNYYIWKKVSVVNSTLIPPKRHSHVAYVAKGLTVFGGIGENGNILCDSWVYSINDNLWTNTTTNLNRLCVARGSFTQNGEMIYIFGGGCNLKYFNADIYLLKLGNSTSPYVWKKVENTSGLSPGGLCGGSIVKLDNYRVLISGGINSSQFQTKTNVIWNSLKNKWIWADSNFLDIDLAYHSSVIFNQSLSPSTCVFIPQTEAVHICPHEKKLMLITYGGVSLNTLSDSLFIYRIGPESTEGSIKCKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWZ1</accession>
    <name>A0AAD5TWZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000683">
        <property type="protein sequence ID" value="KAJ3213706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="226" mass="25696" checksum="6BF324ECA6541EC9" modified="2024-05-29" version="1">MTKETPSWLREPANDHATSHQPLPVKLFVYDCGTSNIWGFPFMSLIDDSKFNGYGSFYLECRNNGAIVENSQASTSAAEAELILYHDKRKVVKIQQIGGKNSGFKIKNLVFGDVNFGNESFISRSNMGTRNADVFYSKTEFNDFTREELNKRFWWEKKSIVSGKLTLVCSNGVIEKVLAIFRRGGIDKVERLGELIIEYEGIQYINLIIATLFTILFREKIDAHIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX41</accession>
    <name>A0AAD5TX41_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000721">
        <property type="protein sequence ID" value="KAJ3213335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX41"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="255" mass="28108" checksum="56DECDFA1FD1E850" modified="2024-05-29" version="1">MSNTNISFYPVFDAAPSKQSQNFLNSDLSLTSLDDYSFVFQGMSLPMFDPEMKQDSAANFVQPVSPPYYNTPSPQSTTFDDFSSPSTLSPYSTTIQSEILFDGSLNMDYMFPTLPTVLPQFGLGLLNSSPSTPLNESNSTEASSTSEILPVASELSTNSDTIPTPQLPPSERPKSKVGRKKKPRPTTAEGILAEAMEKRAKNTEAARKSRLKRLEKFESVEVELEEMKKMLSLCISTMNSNGITLPGEVKQFLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX69</accession>
    <name>A0AAD5TX69_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001127">
        <property type="protein sequence ID" value="KAJ3206413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX69"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3206413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="166" mass="19623" checksum="D9E6F732FBE0A253" modified="2024-05-29" version="1">MPSGSNKIWNDQYQIILLRALCEYRLISLLRFFNLNAQTEYHLKDLLPHINELYNINVFLSDVDEEFPKTEFSLPFEEYETLKMEKRMGSPNTTAATRSSQEASPEVLVKRNSKGHFLKKNKSTVEKKGTDIEKQEESEEETKEKKNYRRNTKSYTNSPKEHRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXA6</accession>
    <name>A0AAD5TXA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000711">
        <property type="protein sequence ID" value="KAJ3213436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXA6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF190">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="805"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="887"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="849"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="953" mass="104247" checksum="359C9855B103AA6C" modified="2024-05-29" version="1" fragment="single">MSEQPPQQHIQVELPPEPAPPATQPALPALPAAQPATQQAPPAAQPATQQAPPPAQQMQQGLQTSVPLINGIPFYKTRLAALISTAILFFLSLISLVIYNYNVWILILCIINLGLYGSSLYFIYTNDNRYATQLILVEIILFVVSWLLGLILSLMLDPTFLSFGLGWSVFNLVINLVLNTPLYFYRKELLLNPILPVQKNEMGQVSSTLTPVPASAPVLQSVVSESPTQNPAVIQTVQNPGVTQTVVQNPAVTQTVVQNPTVTQTVVQNPTVTQTVVQNPTVTQTFAQSPAVTQTFAQSPAVTQTFAQSPAVTQSSVSNEQKMQLVSGVINLTTALVVLTLSPVEIDPNDVNLTFPGVADFFCFLVTQVLQVEKINNKMLSVLSLVGRTCNDYQLLYSLCLLNRACNLIFTDILYSNLSFINSNLLQTLFLGKHNYKIKTVTSINNEMGLGDMSIILQLSTNLNSVIIKYHHLSLNLLLVLLQDYSISTLINLNISNSNLSDNNIHLILTYKNLKNLTLSDDDLTIKTAYILLEHKSLTRLTLHSLRSFEFIPQTLPSNDTITYLDLTGSTIKDDELRKLFENLPNLASVCISDCLSITDDSILKLSKSCLHLNTLMANGLLITDLSIYCLGGLKNLKKLHTSGCVLLTSSVILWLVKELDLEELILDGIPLIQDSFIAYYSFSLSTNECRLNKRCLNSMKSYSSESILPDTSFNSNPLLNFAMSIANTKLPDASFLITPPATPIHDALKSESLMKTGFIKKNSTSIPPSLQQEENYKPRQFKKFNEDAFSKLVKPTKLAIPTAVSALKKPSPGPTQLRRPSTSKVGTNISGKTAAATSSIRFPPARGNSSDSLSNRSFSNKIPTSTVSTLNSLAKKKSAARLSLQITSTQVPKKKDSRLSLQGPKPAATPSKLLQPTKLIPPTKLVIPSKFNLSTKNSTLNKGKINGAIKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXE0</accession>
    <name>A0AAD5TXE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">T-complex protein 1 subunit eta</fullName>
            <shortName evidence="11">TCP-1-eta</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 11">CCT-eta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CCT7</name>
        <name evidence="12" type="ORF">HK099_007044</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterooligomeric complex that forms two stacked rings.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000651">
        <property type="protein sequence ID" value="KAJ3214090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXE0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03340">
        <property type="entry name" value="TCP1_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000045">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000022">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000006">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012720">
        <property type="entry name" value="Chap_CCT_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02345">
        <property type="entry name" value="chap_CCT_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3214090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="552" mass="60613" checksum="114100B787F1804E" modified="2024-05-29" version="1">MQNQFLQPQIILLKEGTDTSQGRGQLLSNINACIAVADSIRTTLGPRGMDKLIVDNNGKVTISNDGATILRLLDIVHPAGKALVDISRSQDAEVGDGTTSVTLFAAELLKEVKLFVEEGLPPQVIIKGFRRASQLAINYIKEIAVSVERKNESEFRDLLEKCAATAMSSKLIHSHKDFFKKMVVDAVLHLDQESLNEKLIGVKKVPGGGMQDSLFINGVAFKKTFSYAGFEQQPKSFKYPKILCLNVELELKAEKDNAEVRVEQVSVSKEYQAIVDAEWKIIYDKLEKISNSGAKVVLSKLPIGDLATQFFADRDIFCAGRVGADDLGRVIKAVGGVIQTSVKDISHDHLGVCDSFEEKQIGGERFNIFEGCPKAKTCTLVLRGGAEQFIAEVERSLHDAIMIVRRAIKNKSVVAGGGATEMEISKYLRDYSRTVEGKQQMVIASFAKSLEVIPRQLCDNSGFDAIDVLNKLRQKHAQGCKWFGVDMESESIADNFEKFVWEPALVKTNMISSASEAACLILSVDETVKNAQSQPPDAGMPGRGKTILYGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY65</accession>
    <name>A0AAD5TY65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent DNA helicase II subunit 1</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ATP-dependent DNA helicase II subunit Ku70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">XRCC6</name>
        <name evidence="19" type="ORF">HK099_006225</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ku70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000523">
        <property type="protein sequence ID" value="KAJ3215749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY65"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043564">
        <property type="term" value="C:Ku70:Ku80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00788">
        <property type="entry name" value="KU70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01458">
        <property type="entry name" value="vWA_ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.290.10:FF:000001">
        <property type="entry name" value="X-ray repair cross complementing 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000080">
        <property type="entry name" value="X-ray repair-complementing defective repair in Chinese hamster cells 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.970.10">
        <property type="entry name" value="Ku70, bridge and pillars"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006165">
        <property type="entry name" value="Ku70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027388">
        <property type="entry name" value="Ku70_bridge/pillars_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047087">
        <property type="entry name" value="KU70_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005160">
        <property type="entry name" value="Ku_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005161">
        <property type="entry name" value="Ku_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00578">
        <property type="entry name" value="ku70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF2">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03730">
        <property type="entry name" value="Ku_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03731">
        <property type="entry name" value="Ku_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003033">
        <property type="entry name" value="Ku70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Ku" evidence="18">
        <location>
            <begin position="299"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3215749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="617" mass="70834" checksum="C44B7AA535B10418" modified="2024-05-29" version="1">MSNWIQNFENFEDDPLLEEDEDDFEERTGLDSILWVIDCSPQMLSSFEDEHSFFETAISCVIKSLQNKIICSDSDLIGVLFYGTKKKQNAFGHENVYLLYDLDVPDVDRILKLETYQNNSDSFLDELGTSEKYAFSDVLWTISSVFSSVTKKLASKRVFLVTNQDNPDQDDIKKLRSSKTRAKDLKDLEISIDLFAMEDAQKPFNYDLFFKEIISEEEGISKSVSAISKFEQFEQKVRSKQVKKRTAFKIPFVIHEGLQISVLGYNLLIDQKKGLPVNLESKTNLQVKTTTKYMCEDTAQYLLPTDIKYFYEYGGERVVFTKEELVGLKNFGDPSLVLLGFKPFSALKMQQNIKHPSFIYPNELDVAGSSSFFAHLLDRMLYLERVAICRLIPRKNSAPRLVALYPDNGEKTEENVDSDAFYGFHVIYLPFADDRRSVIDFKLPESKKLFFNIYFYLDLLLRILVSEQHIESAKKIVKKVGLKKIDPSYFFNPSLQTHFANLQALALKRSIKEDVEDKTLPKTESIHQRAGELIKIHNEFCKSNLVEAEEEARPEKKKKIEVSHDISDANFEILAKEGLLSSLTVPELSTFLKKIGKKAASKKKADVIEAIVKHFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYJ0</accession>
    <name>A0AAD5TYJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008632</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000971">
        <property type="protein sequence ID" value="KAJ3208893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYJ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="510"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="612"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="691"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="722"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="52"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3208893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="931" mass="101878" checksum="C95915184715C53F" modified="2024-05-29" version="1" fragment="single">MLSDETKLDLGENLNHNERNVNNEVEISTSTSSIVENQEKKLEAQVEEPLDALPKRGLKFFLIFVSDQTIIATALPAIGKEFQQFNLISWLASGYLLTQASFAAIYGKLTDIFGRKSLCIVAITLFEIGSFLCGAAPDMNTLIIGRIVAGIGGAGIFTIVLVIIADIVSYEDRGKFQGLIFAVFGVASVVGPLAGGGFTDSAATWRWCFYINLPIGVLTLLVVAVYLPEPKALESSNFWQKIKRIDFIGLILQLISIVCFAVIVQAGGNVIPWNDWKSVLLFVLSFVFGVLFVVWEWKFAPEPLIPVTLFSNKSVGLLVAANFLLGTAILSFVFYISVYFQVILGESATVGGLGTIPLVLGLVILSILSGQLVSRYNRYWIFLLLGTVILMIGSVFMATIQVNTSKAVQMIYLTILGIGLGFLGQTVLLAIQASVTPDMIAIATSVAIFSNTIGGLVGIAVTGSVYNNAVVANLAGLVSAKTASEIVLNPVTIKSISADILPKVLEAVCAAIRTSFLTVVPYSVILFILVLFIKEYDSGVSAVVITIFSALISTISSHDHVPDSVLSAIQLLWVNLIMDTFAALALATDLPTEELLNRKPSKKTDSLINREMWCQIIGQAIYQIVVCFIIYLKPYNIFTFVSPPVSLFADHFTPTVVFNTFVLCQLFNELNSRSITRDTNVFAGVSKNYTFIFIITFSILMQILIVQFGSTIFHIIPGGLDLRSWLICIAFGSGSLPVGFLIRIFPIKQPSEEEIQHVIHHEIEHEVLELQKILITGVEPEVGKNLNQFEREKWKDAIKKTATEVRVLAAFKATARDAFHEGALIGAQAAIHALKPINSPSVLDLSNIMEMSDHEINKTAEVGSPSLRPSQVPNSAGIPLMRPNSRELWKVAGTKVRRQVTVVEAFRRYRKDPIVLDSESVHSQYSQQGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYL6</accession>
    <name>A0AAD5TYL6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000511">
        <property type="protein sequence ID" value="KAJ3215911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYL6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="53"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="751" mass="86547" checksum="FAA6FD4AABF87E3E" modified="2024-05-29" version="1" fragment="single">MSSEVTLPFTANTISETSSNSNDKNSISIKNLLDNFKDKSHSINNKISAHKTYFDGVRGFAAFQVFSMHFMSSNNFLQGDDNSEQLSVRNQTLFSFPFLQTFIGRSELSVPLFYVLSGRVLVTSMLRSAKLESLSSAFVRRLFRLTIPVMGAYTFLYIMFQIGLFHQFYPTSLNGPLHSYRAGVQKPPFEVGYAKGVVDYPYGILWTLHQEFYNSYYVFITAFALFSLNYRGKVIVLTFLIIVNLVNQSMSTFFFIGVALSQLSITKFYEEINKSRYRSILHFSLGLFLFIRLFDYGLVFIRYIDYYFLGFFIGADSNYNPVDSNGLPTLYACLFSAVLIMLLELNQYVQFLFSCKPMELLGKMSFGLYLLHPLWFGGVTPHIINLVASTNLPYVYQYLLVWFGTFLALIPGVFVFYQTFDLGSVFVAKFIYSIIKNAKSTNLFNEKFIQFKTVSIIRSNHTNLESRLWSPITAKLSADYLCNGQNPFAPEKEKKLLKNLDLNKLKNDDVIFVETGTLPTFVKRDLPNIKTSFVLVSGDGDGSPIATLKNSNVDVNLILKNTYLKHWYAMNCDYNPDPNRFSCIPLGISQWNEQRESLAEVLADPAPIRLNSKKFILSSMKVENNYFHRKEPYELGCKVGGPLYDYTECFYEENNGDDKHQKQVNYYKTLASFRFVISPFGRGFDCYRTWEALYLGVYPIVKSSQLDEMYTDLPVLIVKEWSDLSLELIKETYIKFKAKKFNLNKLYKEYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYM8</accession>
    <name>A0AAD5TYM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Glutamate synthase [NADH]</fullName>
            <ecNumber evidence="20">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="primary">GLT1_1</name>
        <name evidence="26" type="ORF">HK099_006098</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L-glutamine and 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Nitrogen metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="20"/>
    <dbReference type="EMBL" id="JADGJW010000504">
        <property type="protein sequence ID" value="KAJ3216019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000006">
        <property type="entry name" value="Glutamate synthase (NADPH/NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000017">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000113">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000022">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.60:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="19" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0274">FAD</keyword>
    <keyword evidence="10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0288">FMN</keyword>
    <keyword evidence="18" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="14" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="16" id="KW-0408">Iron</keyword>
    <keyword evidence="17" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="25">
        <location>
            <begin position="48"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="947"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="1553"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="1553"/>
            <end position="1569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00057049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00068518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAJ3216019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2380" mass="265854" checksum="B36477188A4DACB0" modified="2024-05-29" version="1">MNSNSNENVKHESISSPESCSTNSNLSWAQNLPHQQALYHPDNEKDSCGVGFICNIKAVEDHSIVSDASTILCNMVHRGGGKDIDDGDGAGVMTGIPHEFFTQYFKSQNINYSLVRGQYATGNLFFHITETVRNQSIKIFEETAEKFGLKILHWRTVPVNNSVIGVVSKSKEPVILQPFVVLDQNMHATFDAKLFNRQLYLLRKQATHAITLKNWFYICSLSATTIIYKGQLSPPQVYTYFMDLLNEEYKSHFALVHSRFSTNTFPSWDRAQPMRWCAHNGEINTLQGNKNWMRAREGVLSSINFKEELNLVYPTIESGGSDSAAFDNVLELLVINGVVSLPEAVMMMIPEAWQNQTSMSQQKKAFYEWAACLMEPWDGPALFTFSDGRYIGASLDRNGLRPCRFYITENDRMICASEVGTIFVDPKTIVKKGRLQPGKMLLVDTLEGRVVGDKELKDKICSEKPFGKWIEDNLITMTQVREHFFKKNSGFIGNFLDTTKIHEDKRMLVFGFNFECLNMIIVPMAVDGKEALGSMGTDIPLACLAHKPRLIYDYFRQLFAQVTNPPIDPVRESIVMSLTCYVGPQGNILNMDAAHCDRLRLPSPILDISDLRALQEMNSKFPKWTVAEIDITYPVDEGVEGYVSALDRVIAEVVGAIQNGDRIAILSDRAVSVDRVPLSSLIVGAGLHQYLVDNKLRSKIAIVMETGEAKEVHHFCVLLGYGVDAICPYLAFEAIMKLRRDGLLKKNLTKKEIVDNYRAAADNGIKKVMSKMGISTLQSYKGAQIFEALGLGESVIGKCFSGTRSRIKGVGFDVLAKDALEFHRQAYPTRNMTHGDILPETGEYHWREGGEHHINEPVSIANLQDAVRRKNDNAYEAYSKQSFESIKNCTLRGLLEFKKSEVKAIPIEEVETWTSIVKRFVTGAMSYGSISLESHSTLAIAMNQLGGKSNTGEGGEDSARSTPLENGDSMRSAIKQVASGRFGVTSYYLSDANELQIKMAQGAKPGEGGELPGKKVSEGIAKTRKSTPGVGLISPPPHHDIYSIEDLKQLIYDCKCANPEARVSVKLVSEVGVGVIASGVAKAKADHILISGHDGGTGASRWTGIRYAGLPWELGLAETHQTLVLNDLRGRVIVQTDGQIKTGRDVVVSCLLGAEEWGFATAPLIAMGCTMMRKCHLNTCPVGIATQDPELRKKFEGKPEHVVNFFYYVAEEVRQIMATLGFRTINEMIGRADLLEVDNDRLSAKTTTLDLTPILTPAFTLRKNAATFNTSKQDHLLEKRVDNYMIELAKASIADSTKKSHIDIEIVNTDRAFGTTLSYEVSKKYKEEGLPEDTITIKAKGSAGQSLGAFLAKGISIELEGDANDYVGKGLSGGKIVVYKPKESLFNSEQNVIVGNVCFYGATSGKAFISGIAAERFCVRNSGVVAVVEGLGDHGCEYMTGGAVIVLGKVGRNFAAGMSGGYAYVLDLEKTFYPHCNQEMVDLEDVQSAEDIEFLKTTIEDHVKYTGSEIGQKILKDFKNYLPKFVKVFPQDFKAVLKERKLELQQQQLQQLVTASKNSQDSKSNPTTESQDESAEEASISSPVRQTIPVASSVLDIEDAMGDFITPDPNETTVLDKLRGFSKYKRKGDVYRSAGHRVKDWKEVNNRLPPAETKVQAARCMDCGVAFCQSDNGCPISNIIPKWNDLVFNDQWKEALNRLLLTNNFPEFTGRVCPAPCEGACVLGINELPVSIKSIECAIIDKGFEKGWMVPYIPKHRTGKKVAIIGSGPSGLAAADQLNKAGHWVTVYDRNDRHGGLLMYGIPNMKLDKSIVQRRIDFMKAEGVKFLNNAEVGKNVDANTLRSKNDALLLCTGATWPRDLRIPNRELDGIHFAMEFLQRNTKSLLDSGLKDETYLSAQDKNVIIIGGGDTGTDCCATALRHGAKSITNFEIMPTPSKVRGVENPWPQYPRVMRLDYGHEEVKQVYGKDPRQYSILSKEFVSDGKGNVKGIKVVTVEWNKDERGQFKMTEVPNSEKFYEADLILLAMGFLGPENEILKQLGVTQNKRSNIETPKGKFSTNLQGVFAAGDCRRGQSLIVWGINEGREAARNIDVYLMGSSVLPAKGGIYERDVEGVNRTVKLKFLKKINFNYLLNEKENFVFFSGAIEFNLLNNLYTLIDNGFQPSAEDFRIACIKNNRVEILRTLIFLNSSLLKNRVQVSKINQDLKYKISFKNFKLLFVYFNSNQYSNSERPALFQEEFDFKQYIILKQNKKVQFLNGTFDIDLQVIQFQNRITIQSHFEDLFIAVKEKNCKLVYYFLCEGLIDPSLQNNKAIMFAFQKRYWDIVKALFIDERVYQNLSWYFRGVLSPLGGNMYNNVVAKLFRYFSRNDYTTIRFNFRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ29</accession>
    <name>A0AAD5TZ29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005523</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000433">
        <property type="protein sequence ID" value="KAJ3217310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ29"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="647"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="676"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="717"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="754"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="159"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3217310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="857" mass="95442" checksum="683D2C377A3FDCB2" modified="2024-05-29" version="1">MLGPVGPALFQCHEDQTTIGRGKRNCKFSELNMNKLIGQLIGDPYISLNCTSSECLHYSQLPNYVRPDAASGFSPLIMFLTFGGAVILFLICLITFIRQVRSSESDVVAFDNEEHIPLNPNMDIDDRRRFMMAGHVPCSLAFRDLCYVVDVTKKKKELADEVDQVRSQQGSQLHVLEGIEGIVKSGEVMAIMGGSGAGKTSCLDILAKRQKSGVVSGDILVNGKAINTSEYKSIIGYNINVSHVKFFRYVDQEDTLMDTLTVSETIMYSALLRLPPHMSQESKKYRVYETMQELGILHIANRRIGSSGSRGISGGEKRRVSIACELVTSPSVLFLDEPTSGLDSYNAYNVIECLVSLSRNYQRTVIFTIHQPRSNIYALFDKLLLLAKGKVVYSGPAQETVIDHFSSIGYTCPLGFNIADYLVDLTMHVVNSSDSPENKDDVIEIDDKTNGKLAASKINIKAQQESILFTPRQQTLKKEANKGKENISDSHDAFSLAEGNSHDLLKENNKSKSLSVNNKSMNGSRSNSVNNITEIKDHLEHLIQSFKNSAISKENQSYFLQYEVAPGNLEQQLGSDEDVDEANHNSFKTIKKAFSLSFINGENGNFFNNLHIYGSEKHIDWFTQFKILSDRTFKNLYRNPALLQTQYVLSVIAAIACGTLYYKLSTDIAGFQNRMGAFLFICALLGFGCLSSMPAFASERLIFVKERANSYYKPVTYFSSKVLFDIIPLRVVPPVILGLIIYHMMGLRTESPVYLLKFLFALVLFNLTAASLCFFISIVFKDSGVANLIATLIMLFQMLFGGILLNKKSIPSGLSWLNTVSFYNLAVEALVVNEVNGLALYENKLGLMIDVIEKNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ68</accession>
    <name>A0AAD5TZ68_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000388">
        <property type="protein sequence ID" value="KAJ3218291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ68"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05379">
        <property type="entry name" value="CAP_bacterial"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157:SF1">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041909565" description="SCP domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="47352" checksum="A1D74D87403492D1" modified="2024-05-29" version="1">MIQKYLNILLIALLSINTTVSLPKEDNTPLFPKPILAQNLQPTNKVQLTNVNKIDTIKIGSNDIIHHVVSLSEYSILSQKLFLLQNQLRKNPAKYYQNLLKEGNNETAKMLSNNLTPVQLQHDQLGVESLKYSLGLQLSAQDLIVEQSHSGEIGHIGSTTPYDRIHRYGDLSKGKYGAGEIIVYGLTDANEIINSIINDKLMFENLRRENFKSGAISCGYHNSSFQTSCVFVYADNFINKLKTEHKFYNNVLRALGLYLLLVLFALPTTNLTRRSEIHLPGSLFLGSPNNETGIIKNKSMTKKEYETLEQVLFNNQNGIKKAGNLLVANQGSTGVVGHYTSDRTSPTDRMNKYGKWNKFAAENISYGTYKDSFNILAGLINSPGHFKNMFSENYLIGSVSCGPHPIWVNMCAFEFAYAFESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZA5</accession>
    <name>A0AAD5TZA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005359</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VTA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000411">
        <property type="protein sequence ID" value="KAJ3217741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZA5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.270">
        <property type="entry name" value="Vacuolar protein sorting-associated protein vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044538">
        <property type="entry name" value="Vta1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039431">
        <property type="entry name" value="Vta1/CALS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023175">
        <property type="entry name" value="Vta1/CALS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041212">
        <property type="entry name" value="Vta1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46009:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04652">
        <property type="entry name" value="Vta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18097">
        <property type="entry name" value="Vta1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vta1/callose synthase N-terminal" evidence="9">
        <location>
            <begin position="12"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Vta1 C-terminal" evidence="10">
        <location>
            <begin position="371"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3217741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="411" mass="46142" checksum="F61759800D382FFE" modified="2024-05-29" version="1">MNLENVPVDLKNIQPFLQRSSELQKREPIVSYYCLYYAVKLAIEKGPTENSRSFLSKLLDHLEQEKKMLSQHEEISNEVVGLAHVENFALRIFNNGDKEDRNGAATKKTAKTFLAASQFFEILKVFGDLNEDIQQKMKYSKFKAADIMKSLNEGRVPQAGPPKSSKDENDINILQENSSTANQPGSLPTTATFIEEKAPIQNAVNPYEPQPLQGMHLQQSFQSQVDHNPYQPLQQQNPYLPLHQQKPIDNPYLPNQNPVYNQNPYISQQTPSFVNQDPYEPMTVAPTNSVNFEPSAPPISSPNPYITNSNNHGDIKLGSQLETTPISNHNQHQQTNFTVNQTQSNFSVFQTPGFEGNRGFGADPFAVDHTVIANAQKAAKHAISALQYEDVDSAILNLKKAISLLQPFHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZA7</accession>
    <name>A0AAD5TZA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000649">
        <property type="protein sequence ID" value="KAJ3214116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZA7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.100">
        <property type="entry name" value="Set2, Rpb1 interacting domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013257">
        <property type="entry name" value="SRI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038190">
        <property type="entry name" value="SRI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08236">
        <property type="entry name" value="SRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="145"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="44"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="378"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3214116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="420" mass="48038" checksum="ED97335F2C9A77A3" modified="2024-05-29" version="1">MNAMILKTIKDLPLTSRNAIVDYKIDEVVTKLLEVKDAPDVVEIAKEENPTNKRLSEDNRVDSDREKKFRHEDRRDSSRDSGDDRSKNYSRDRYDKYDYRGSRSFNSSSWKSRSYYNSFSRRFNESYSYSGSNSNSNEVQSNISETTENCWAKAFSDEGKPYYYHTSTNETTWDRPEGYQSPGGDNQNGDDQISNKTELKSITQVSQAELDDILKEEIARAEKLKLEELKKKDVVKSTNGKHGSVKLSSNSESSHRSKTVDPKKLEVKFKKLVSEVVIKTLSKYKADINSSDAFKEVARKVTEKEIRSLKPGDVLPAVVGDDIKRKIKKFVYSKLTEQGYIKKGKKTTSIDDTNIQIDKYDNKQDDISKECIDSYSNDKISTINNTNSPLPDLITPSTDNTLNNESTDKNDEDDMDLSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZG4</accession>
    <name>A0AAD5TZG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000393">
        <property type="protein sequence ID" value="KAJ3218167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZG4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="83" mass="10167" checksum="ACEB767F4C33308A" modified="2024-05-29" version="1" fragment="single">RKKPEKSEYFQDHLEDLHSNKVYIDPNKRDLLYCLGSNGKKLRYTQMQRRKESELKRYRKVRERYQVATEEVVNYEITKKNVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U082</accession>
    <name>A0AAD5U082_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit gamma</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_004464</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000316">
        <property type="protein sequence ID" value="KAJ3220053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U082"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04198">
        <property type="entry name" value="eIF-2B_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051960">
        <property type="entry name" value="eIF2B_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="10">
        <location>
            <begin position="9"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3220053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="319" mass="36400" checksum="D7960079B9C6BFCC" modified="2024-05-29" version="1">MGDIQEFQAIILAGVGSRLSVLTEDLDKVPKALLPVANKPMLHYQLQWLESAKITNIIVLAQNSARQKINEFLYKTYELSSRQTKIELICLDEAEGSADSLRHIKDKIKFDFIVLSSDLIIDIPAHTVLDTFRALRSTVTVLFSESSKAERSEGRGNKDEDTSDYVGINHKKARLLYMAPKVDVDDDTFLSLHMALIKKFPVINFHTHLRDAHLYIFNRWVMDLIYSKKHISSLKADLLPLLIECQYNKNLYEREGIDQFQPQSQSMTTAYLCSTTGTPDGMTIPPFMRTNTVSEHSSPNQLYRGMIGMNYSYDVLTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0M4</accession>
    <name>A0AAD5U0M4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF952 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000317">
        <property type="protein sequence ID" value="KAJ3220044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0M4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.20">
        <property type="entry name" value="Protein of unknown function DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129">
        <property type="entry name" value="BLR1139 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129:SF1">
        <property type="entry name" value="DUF952 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="13219" checksum="6F139F2CE718E11B" modified="2024-05-29" version="1">METVYKVLTPEEFKNFEAEAVGYAGNQMDKKDGFIHLSLHTQVAGVLSRFYKTNLKVYVLKFEINKEKLKFEKPCHFSDETFPHIYHNQLLKSELIEVINLQRTNLEKDFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Z6</accession>
    <name>A0AAD5U0Z6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000269">
        <property type="protein sequence ID" value="KAJ3220841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Z6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="480" mass="55341" checksum="A43D43F345CAE8A1" modified="2024-05-29" version="1">MFSTNLIALCPVEPIGILKHCPEDPDAKFQEEIFENILKNTQSYVIDVFIAYGCLRSKHPILFQPEFGGSPLCVGIYYLNKAIETLKILPANERYRIEALQSMFGVSCLLFYFGKKNDGLFWLTEVYKAAQHFNFDRPTAVLEDLDLFTVKTEEKVEPTEEEKEALIEKKQRRLLWARTMEILALVTSPLIGTEEEHFYMIDEQQWELIGVKRLVNSAYDVVDLTIEMQLCFLYRRSIRYVQAPIEETILQNDISKIHVALVSWHENIPKSMRTFDSLTDFIDGTRVFPECDWIDNAYNLSSNCWFLLALIKIHSHNNLFNPNQRFKFSENFPVDGTSLDFILVCFRALTSILLITLPKELELKLNSDERPFLYNIAVDILLTVTLHETIQIAVDCLKKGLGWALNLKLRQEVINLHLDRIYLKILKERNNPFSQSSYDMLIPIVETLKRDDINGIEISDGSVEGSINGSSTLGISEVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Z9</accession>
    <name>A0AAD5U0Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBL3-like ubiquitin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000476">
        <property type="protein sequence ID" value="KAJ3216483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Z9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039540">
        <property type="entry name" value="UBL3-like_ubiquitin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13881">
        <property type="entry name" value="Rad60-SLD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBL3-like ubiquitin" evidence="2">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="72" mass="8015" checksum="BD5E4A444231C5B4" modified="2024-05-29" version="1" fragment="single">MSEAATNPIQPKEEERSTLTPDDNNSGVSDKIPANKLSLRFLLVNGNKSEVMYNLTDTILDVKKNVLANWPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1H2</accession>
    <name>A0AAD5U1H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000259">
        <property type="protein sequence ID" value="KAJ3220987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1H2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="406" mass="46979" checksum="3C775B4E2EAF9E69" modified="2024-05-29" version="1">MEKELIKFLLNTVNDIRETLELNDVEKSHSLLKIVLEDAERHLGSCVNTGYPDSFSNTNQTRRAIPGTGECVVKNDSKLMILDKEKEKTLLANFPIELILQILPHLHRAEGVANLQTFNFAKFNGNVPKYYELFFKLYPFSNIRRLSVPIHKDEVYDIPCYTIFKNLVELNLLLTPGWSKTIMQSILSSTVQLELLQVSEVDIMDYKALEIVSECSKSLKNLTALRFLRPKFQRTDMDTLLIEPTSKREYVEKFIFAIFEVLKNLGHNLLLFNFDAALYDIHIEDFGENLINSLVTHCENLEDFLFDTGALLSFSKENIQKLCTSLKKLKTVHLNSCAPENCEVFLQHKIELCRTTIQCETEPDTDETDEEWGDPYLMGDDYFDSEGSFFYDSDPVEFMDYEPFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1P5</accession>
    <name>A0AAD5U1P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">High mobility group B protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HMGB4</name>
        <name evidence="5" type="ORF">HK099_003405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000223">
        <property type="protein sequence ID" value="KAJ3221560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="130"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="130"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="267" mass="30519" checksum="2B6F7C4D15BE20B1" modified="2024-05-29" version="1">MNNNINNINFSQPGQHLVTYIHAILTGLNGLISLIQEDSVPGIDLSSLSPIVNASLISTNKVLTSINRQNFSVSNQQQQLPHQQIQQQQNFNSQQQQQSIQQQQSFQQQQIKQVISTTKPKKEKRDPLAPKQPMTSYLLFCQDVRESIKQQNPTWSQRIIATEMGRLWKEISGEDRVRYDELAQQKRDEYNQAMVIYRDRAGIAHPVKKSPKVTPINESEQPSLSPISPLLNENSNITAFVKAVEGKRDAADNLELLLHENNKRQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U210</accession>
    <name>A0AAD5U210_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Tubulin polyglutamylase ttll1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TTLL1_1</name>
        <name evidence="11" type="ORF">HK099_003486</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tubulin polyglutamylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000228">
        <property type="protein sequence ID" value="KAJ3221476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U210"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF31">
        <property type="entry name" value="POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="196" mass="22716" checksum="9811730505B5E179" modified="2024-05-29" version="1" fragment="single">YTYSSPAQKDAYVVSKYVENPFLIGEKKFDLRLYILVTSWRPLIAYKYGQGFARFCSIKYNTDTEDLDNNFMHLTNVSIQKFGEDYNEQNGGKWSWTNLLNYILGTKGKKVLQKFIQDVDKIFIHSLRAIQPLMSHEKHCFECYGYDIIIDSTLRPWLIEVNASPSLGGTTQTDKLLKHSLINDVLNIVIPKDFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U223</accession>
    <name>A0AAD5U223_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peroxidase</fullName>
            <ecNumber evidence="13">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CCP1_1</name>
        <name evidence="16" type="ORF">HK099_003169</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000211">
        <property type="protein sequence ID" value="KAJ3221749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U223"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000005">
        <property type="entry name" value="Cytochrome c peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 13 16" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="81"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3221749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="269" mass="30201" checksum="F7B78ECAB82E0F7B" modified="2024-05-29" version="1">MFTRQLLRNNALFRVNLRKFSTQNTPKPTKSKAVPLAFLTFTGLGAASYFYYQQSDSKPTFLKKPLNYQEVYNKIADILEDVDYDDGSYGPVFLRLAWHAAGTYDLNTNTGGSNGSTMRFNPESSHGANAGLKIARDRLEQVKKEFPAITHADLWSLAGVVAIQEAGGPIIKWRPGRKDADSETACTPDGRLPDAALGQDHEDKATKELMMLPADLAFINDKKFKSFVTLYAKDEKKFFEDFAYSFQKLEELGVPFDENTKPMVLKPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2G2</accession>
    <name>A0AAD5U2G2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Elongation factor 1-gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EEF1G</name>
        <name evidence="9" type="ORF">HK099_005450</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000424">
        <property type="protein sequence ID" value="KAJ3217502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2G2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03181">
        <property type="entry name" value="GST_C_EF1Bgamma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03044">
        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000006">
        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1010">
        <property type="entry name" value="Translation elongation factor EF1B, gamma chain, conserved domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001662">
        <property type="entry name" value="EF1B_G_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036433">
        <property type="entry name" value="EF1B_G_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF1">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00647">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01183">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89942">
        <property type="entry name" value="eEF1-gamma domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50040">
        <property type="entry name" value="EF1G_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="8">
        <location>
            <begin position="53"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="EF-1-gamma C-terminal" evidence="6">
        <location>
            <begin position="233"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="EF-1-gamma C-terminal" evidence="6">
        <location>
            <begin position="270"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="181"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3217502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="348" mass="38784" checksum="D0BA3D94ED864B8D" modified="2024-05-29" version="1">MGVSNKTPEFLKKFPLGKVPAFEGADGFTLFESSAITYYAATHKDSTQLLGKNKKEAALIHQWIALADNEFSPIAAAWLYPIFGYYPFDHKSTEKAKADAKKVLSVLDAHLLHHTFFVGETVTLADISLVSALVGFYKTVFSPEFRASFKNVTRWFLTCVNQPHFKTVYGEVALATAMKVAKPAEEKPASTPASPKTAKAEKKEKAPSAKKEKPKKEADEEEEESYADEKPKGKNPLDLLPPSTFVLDAWKRMYSNNDTRPTAVDWFWANAFGSLCVLGKDNANEIAGYFVFRGDGIPAEVSDSPDFESFNFTKVDTSDKKVQEDFNCYMAWDEVIDGKKFADGKVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2P7</accession>
    <name>A0AAD5U2P7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000261">
        <property type="protein sequence ID" value="KAJ3220953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2P7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="664" mass="77404" checksum="E496DC4589C46A71" modified="2024-05-29" version="1">MKQLSQPLRQSKTKEACLRCRSLKRKCDSLKPSCSRSDCQYSLEKKKRGPKAKYDKKFERNHLHFNVYENVKSENQYSSRTDVNSSPLNQRISKFDGSTNSFGETSDTSSSYTTFENHVNTIGNLNVLDETSKFNTEKKIPPTVNSTDAKVHSAVDILFNVLNEELNNLNNQNSFHLTREEAISLNDDFQLFNDQFLNLSNNCNYLYRISVEKFLWHFKDAKKLLNYEINDNYHLNEMDNNSLEIILLDGIFDNSISISFLNLSSSNVFEKLKFEVFSANSSFNFMLKRQLYQKALTFQNEPFINITFANQCLRSNHPMLYSPKFGDPLKASSIFAGENVRAEYYLDDLLKAAIHCKYDRQKNNCKEIGFKNRRLLWAHLLIFSSFISNMYSFINEEDHMYMLDEEVWKNEVICDEPNRPLYLANVLSATRAIRLINQPYSTSKYRNENNFTFVLNCFAKNSVAEIHKNLIYWYNGIPQENLKMISLKNFITNIKYQNDFFDINCLEKIGLNLIFISILFKIHYFNVFSNPKADVDKKMNEIFLVYGDENDFFEITSLDFILVLARALASLFLIPENTGDFKSNTNFFYDLKFDIVVAILLRDNITILQDCLKKKVCGWCGDPSIRFEVSGYIELFLEIIRLRNFPLGNNILLTLTNSSKIGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2R2</accession>
    <name>A0AAD5U2R2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000337">
        <property type="protein sequence ID" value="KAJ3219516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2R2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="313" mass="37234" checksum="760190C3C1A635DA" modified="2024-05-29" version="1" fragment="single">ETFCSTKSGKLIFTHRRLIWIEAHNNQVPSVKKLNEVSFSLSILELTKYIVGNMVEEYSETKTKKYQPKLNYSRKSKTKETKMTSSLNDNYYLIVHHNSEVFKFYPFNFEEIKKIKEIFKYLTNTEPFTEENFIKEVLSQQLQSHRKKILTKLVAEKDPWIFNSYKLNEILDNLTQEHGKQNLFDLERLFHSCRLESEVLKESLPILKRIWSDTRSEEVRLKVLQVVDRLVDRVLMRQGDPVFETTFQWLRLLEETLDPYKSKQALPLIISIVNRAKIIQIEPLTPLNQPVLRSMFDDFDDFCLIKENLFNVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U334</accession>
    <name>A0AAD5U334_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tubulin polyglutamylase ttll2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TTLL2</name>
        <name evidence="4" type="ORF">HK099_002275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U334"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF118">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="291" mass="33363" checksum="F2541E26B452F0BB" modified="2024-05-29" version="1">MSRGRGIFLVKDLKDCIYDTNAIIQVYIERPFYVVVRSFNPLVVYIYNEGMARFATNKYNTTDIKDVFSHLTNTSINKFSPTLQNEKEEIGPGCKWTLNTLNSFLKLKGINFDEIFKKIKAIILYTIIPITNDVILHSYSCFELFGFDIIIDQNLKPCLLEVNLSPALSVDSSIDIEVKKPLLSDIISMMNYTESDGDLAFVAEENLHVKNSSSISLTQIFFKLNKRKNSASSTKTKEQNAKERNSFNFASEVGKFEMIYPFNELTKKHSNLKVGQPVTREILQQIRKKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3E7</accession>
    <name>A0AAD5U3E7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PDE7A_2</name>
        <name evidence="8" type="ORF">HK099_003581</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000235">
        <property type="protein sequence ID" value="KAJ3221355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3E7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="7">
        <location>
            <begin position="117"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="208"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="450" mass="52327" checksum="B4BC220AD479EB8D" modified="2024-05-29" version="1">MIIDYPADRQLNELVLNLFTCFAGLIFSNILSYGLERQRRDLFQTKLELNNALMNSPYNFRKSSQYNGHPAFDSVATEVSIEMSDISTVSPDSSETTMEIDIELEKVDSKSNIIRKSDNDFEKSMSNIRRSSSKKGIMSIKEYLNIVDEYNWPIFEFTIATNGKPLTQLMEHICITSGLLKRLNLSEMHFLNFIENIEKGYHKDLRFHNSQHATDVVHCIYYLSRLPKIRKVLNDEDLLALYIGAAIHDHDHPGFSNKFLQETNDSLAKRYNDRSVLENHHLSSSFAILDKKENNFFSSNQTQLYNDFRSSVIELVLATDLALHVPILQQFKSRGAQFNPLTINEDKNLLMRLLMKCSDVSNPTKNFETIYSKWINLIMKEFYRQGDLEQKYFGSVKSPFCDRKKSDEVGKCQKGFIEFIVFPLFESLKSFESNFNDKWLLSNRERFSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3U8</accession>
    <name>A0AAD5U3U8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="2 17">1.3.1.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">tRNA-dihydrouridine synthase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">DUS3L_2</name>
        <name evidence="20" type="ORF">HK099_001289</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the dus family. Dus3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="2 17"/>
    <dbReference type="EMBL" id="JADGJW010000135">
        <property type="protein sequence ID" value="KAJ3223315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3U8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25585">
        <property type="entry name" value="zf-CCCH_DUS3L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 17" id="KW-0288">FMN</keyword>
    <keyword evidence="16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11 17" id="KW-0520">NAD</keyword>
    <keyword evidence="9 17" id="KW-0521">NADP</keyword>
    <keyword evidence="10 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="16 17" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 16 17" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="19">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="19">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="16">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="16">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="200"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU291113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3223315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="440" mass="50128" checksum="3680DD1DE92A1AFB" modified="2024-05-29" version="1">MKEVNTEVPKKDLHSCPIKKEFLKIGGWMNEMGEENEGKRKFGVTGLSGESAIKRKGQNKNRKNTHSKDKIKLCHSKVKNGDCKLGSQCQDSHDIKVYMESKEPDIGPNCFLFDTFGFCKYGVTCRYANAHLSNMENVKNLEIFDEEQFGKEVKCIIFKWLIQYFKIKNAMKPGFQKSIRNKIKTKSEVVLAVTEFVEQKTKINSEKTDLLREIKALKESSDVENDELNKKKKRLESLEEELKEVKLTSREKVKLDFKGKTYLAPLTTVGNLPFRRICKEYGVDITCGEMALSQHLLQGNSLRNLNLKFYFSAQKHEWALAKRHKSETFFGLQICGNDALLLSKTCDLINDNLELDFVDLNLGCPIDSVVKSGAGSALLGKSSKLHTIIQSMQHTLDIPLTLKIRTGIFDNKRVAHKLVEQFKGLNISNVTLHGRSQQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3X9</accession>
    <name>A0AAD5U3X9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial 37S ribosomal protein nam9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NAM9</name>
        <name evidence="9" type="ORF">HK099_000837</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3X9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="8">
        <location>
            <begin position="107"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="323" mass="38111" checksum="D190EB1F7F6BB7DC" modified="2024-05-29" version="1">MGLHVARPVIDRYNLTKKLIRMSWSKYNLYNMATKEREKESSNLRKSVFQQRWAAKKQLRAYYVPNISERQFIDRHFTTKIKLQHLSKEDQKKVPPAQTLAFAELERRIDVVVFRSHFQDSIFNARRIVRAGHVKVNGVKCNIPCRSLKDGDMITVDPAAVVTLKPPRKRKEILKDGSPNPYPETPRSKERRFVPQKYMAPWMFVPEYLEVNYPTCSTVFLRSPLPQPSRVEIPSPLDPTTHQLGFEWYATIKRRKTRKTIWSPMVINGKTCRLKPKFDQMLRNDQFVKRMAVQGKKVNLRRVKVKYTPRFVRKVVSKNKDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U481</accession>
    <name>A0AAD5U481_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein mS29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002435</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000180">
        <property type="protein sequence ID" value="KAJ3222333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U481"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019368">
        <property type="entry name" value="Ribosomal_mS29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12810">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12810:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10236">
        <property type="entry name" value="DAP3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3222333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="291" mass="33239" checksum="E10FBF13E21EE935" modified="2024-05-29" version="1">MSVPSFKLSVNHFFPQQKLITKNLLKLVSKTNSILNNENFKSKALVLTGKAGIGKSTLLFQQEAFFKKNGWTTFNLSNLNSWVNGTQPYENKKPLVRQAELELNVLQNNFLQKEKPEEHDGIVGLRKFFDKLKESPSDRSPVLLSIDDFNAFFCSTEYYEDGKAMKSSRLALIKFFEDIINEGIPNGVIVASLTSSPNFKNSQLPNNLKKPLWTFQALSEAEKKPNSTFDILNKANHNSTVKFENFFVEECLDERQVQLLLNETNFLTEKENYTRIWTLSGGNPRKVLSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4K6</accession>
    <name>A0AAD5U4K6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000167">
        <property type="protein sequence ID" value="KAJ3222616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4K6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="1">
        <location>
            <begin position="104"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="203" mass="23583" checksum="59B1AAAE7A06E4B4" modified="2024-05-29" version="1">MVDRSLPYKQFDCKILKKKKDAHGRLARWINNFHFYSPDMRFRPVNDTGADPIPKCHVIAITLSTKSIDSVKDWPLYIAHYLQSGDQNHFLRKVRNNKSVPYLPQDQRQAVLKRGHSRWSLANVNKRNGSRISSQIYWPQMLDDYTKYRLHCAQCQLAKSNNRNPNPAPMTPLEPDAIAFKPPYNDSDRLQLVGQLPNLVRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U639</accession>
    <name>A0AAD5U639_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4360 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000059">
        <property type="protein sequence ID" value="KAJ3225511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U639"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="44780" checksum="2C658A4AEB6249F5" modified="2024-05-29" version="1">MNVHKYINLPTFGVYILGFVYIIMFIFGIVIFVGNAPQGSQGIYTGLSRIWMLIMIGIMVGMGYSSYLLFQFNDPVKVVLFVLSILLTYGLYFLASVLFRDTAHLISSMPGYYLLLPSYINIMLPFAMSNIHDVTWGTRPQEPEKLSGKLLPKNKMEDGLAEMHSTKANGDIEIDVNNLQSLIKPPGEDERPKKKRVVVSKEDQDKNVRFSILFLFFFVNLLGSAASETPPTGTISIGPLVNSGSGCPQGTVSAILSSDELVLTYDSLTAAIGPGIPIGESRKNCQLATQFTVPAGWQFSFDSINYRGYLQVDENVTAQLRGEYRFQGSSVASTITSLSQMDNGSYSIIDEFTNVVWSQCNHRSFLYINSLIRLNGPNGQSGIITVDPANQQVTQIYGIKWKRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U672</accession>
    <name>A0AAD5U672_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000156">
        <property type="protein sequence ID" value="KAJ3222861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U672"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="16312" checksum="B05429CAB5E4C197" modified="2024-05-29" version="1">MIPQIFQKSSLEGQNQTYLTKLHLKRERKKLIRQVKFFNHLLLKLNCKKQEYNLVTKKQFKHNKYDTLESREIPEEIKMFSFSKDFLTFFVPKELVELEFWSRIELEGEIGAIVRDLYELEEIIKRLRNIPHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U698</accession>
    <name>A0AAD5U698_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PAAF1/RPN14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U698"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF19">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT RPN14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="179"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="397" mass="44432" checksum="F7B832A8857ABDFF" modified="2024-05-29" version="1">MTNEKRLSTNQNFFYDCQMDFGVDLIKPSSKFWFSSRNLTKDEKTKHDYVHVVSASELSMDDPNLIPTKINNLSFSIKNRLNDKSTTFKSTNKFLKTEKSEISSLHTSPLNDIFVTSSNNSVNLYSTKDLKCLKELKDLHKLDINNAKFFPSGKVLLTASSDFTLKVTDLEGKVNPIDYFSHKRAVTDTDVVERGTNFISSSYDGTVKLWETATATVMNSVSLSAGKINAISLEGDFGSKSGNLVFAAADEGAFVLDFRSKNLTAPISFQSNNNSLSLVRSLDVNANNLIAFGCSFGNIVLYDKRNPKEELILVKKSKARINKIKFLKNLESSLMFSNGEGSLSLVKFSQNLDDFNFEKEFIGNDLNSTTFDFFEEEKSTIFAGNEIGELTVFEDFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6K4</accession>
    <name>A0AAD5U6K4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytosolic carboxypeptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AGTPBP1</name>
        <name evidence="5" type="ORF">HK099_005652</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000045">
        <property type="protein sequence ID" value="KAJ3226067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050821">
        <property type="entry name" value="Cytosolic_carboxypeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040626">
        <property type="entry name" value="Pepdidase_M14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756:SF11">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18027">
        <property type="entry name" value="Pepdidase_M14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M14" evidence="4">
        <location>
            <begin position="1101"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="1334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1409" mass="160597" checksum="BF5D28604B930BC1" modified="2024-05-29" version="1">MTENNLQYFSIISSYKNVNARIGPLNKQKSTYLNKNSKTKIKKKISKNKSVSATSISATSSANKLTSNSSSKISSNIGIGLVHPLTKLLEKLAVSVSNYSKECNLQKNLSAPTLIHLNNEEYMERNRYISNENFDEKQVAVKKNLKNTKKKYLSRLSSNERINVTIPLSTCSDGFKSQKSRKEKIIRKKSVKEDDLFRIVEAPKYFVEGDSDVKEDDNNICFNDDTQLCSSLQKPKIVDLNATSQELITLNITGLLPLPPVSSTENKQLTREISSVVSSLSSLHNSSNSLEDSESLNMESESYDFSKIENFNENTLLIKETIYGEIDQDKISNFETSDNTPEESDLTREILKNSLENVTYTNSDTRLSKINSDTTLATKIYLIEIQKLLKEVFRLLKREGYISSENCIQKLLFSSSSIVNYPFSIFVVIKCLGIANEIYPFVGEDHSNIDQCKTISTCSNQYGSNVFTSYSKNSLIQILLILTTPNITEQVSINLNYFIKKGVINQLLKWLSVLISKKENFLVNESLIFDILEVLKRLGKFEAKISVYARLNNCIKPLITFLEEIFVIYLNSKIEKRLVAINMEEYGEKKYNEDYISDVIKSDKKEANVLILIKAGAVNFASQVILERVHYSITPQLEIIMDELQDLDDNLTVVLDVFGILAKGRSTEVIKSLIPKSIASCLDVSDGFPIKFLIMLLTILLNNSCITTNIKLKKNGSNESLKKENLNNLGGSSGSINCSKTNNVFKEQILTNTPPSNEGDKNSTILINLNVIKSILRILIDVSKNENFYKILKDFRFHVTLIDYLLRPDFTDPQLPSQVNSQQNSSTNLFEFQKPVDMKKCMLKPPIKRLCTVTTQSLQLLRILIPPVALPFIEKILVDKYEIDENCSSELTEKEKLHLNFFFPEIDELGSMFSEEINLKSLSINEILFQNKTILKKKVIKAASGSFKNSFQKQGKKSNQSELKRLSFETIYDFANISEHYTPSAGRLVYNHRDCGVKRNSSDLEFDSSFESGNLALAIKISEFRYQLVINSDVNTSMGKHNQWFYFSCKNMKPRVTYTFTIINMSKSNSQLNFGMQPVFFSTLQNSWMRVGEEVYYYKNHYYKNPPSENFIDSADELYSSFTFQFQFPNSDDMCYFAYHYPYTYTNLQCLLDNISSNNFITRQLLCETVGGHRCDLLTITATDVESNLRKPLSERCYIYLSARVHPDGVIVGNHRTSLAGLDLNRQWKSPKKNESPTIFWAKNLIGHLCNVIGNKPLLCCDIHGHSRKKNVFIFGNDISKEGNFDHIFPTILSNICSSFDLNNCLYTNDPAKEGTARVVWYKEFGISSSYTLESSYCGATVGEYKGFQKYESILLSFHLKRHNITLEYAALARLSHLKRPYFIEAQPESLQKQHLSKELKKLQKSRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6P4</accession>
    <name>A0AAD5U6P4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">STK4</name>
        <name evidence="7" type="ORF">HK099_001469</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000141">
        <property type="protein sequence ID" value="KAJ3223167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6P4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001091">
        <property type="entry name" value="STE family protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF2">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="662" mass="74075" checksum="331BB14319E58C38" modified="2024-05-29" version="1">MSRRKMSEFERVHSLYNLFDDGDPKKLFDMHEKLGEGAFGAVYRASLKHTGFTFAIKKVHINKIENSDSIKKEIELLKGTKHINTVQYFGCYPVDDSIWILTEYCGAGSILDCIQLTKSVFSESQISIVLSSAVAGLAYLHSQGIVHRDVKCANILLTEDAGVKIADFGVSEKLTQSVQVRNSIVGTPYWMGPEVITGSDYGTSADIWSLGITAIEMAEAVPPHANLHPMRAMFKIPFEDPPTLSHPEVYSYEFSSFLSKCLVKNPTKRSTAAALKNLPFISHLIQSSSDAALRTPLQLKVNQVLAAKRHKARKLQLRAMNADALKAELSSTMKPLPVLPEDTETIKSHINNTVITKSTNSSNVSESSEIPSANYWDKDDIDFGEHNSHHGTIIKTTVSDDAGSVVINEDEPKVDILLQTNKSKKAAVIENHNLTDFNKIVNENHLHIGEYSNVKSINQIHHSANFSTISKNSSDDSVGDNNDLESEKEETFKLKKNKFLLRLENFKKMLNGLLIPENEDDEEDIFDMKDSSNLKNNESTIKKEDVVQKIDLHSNHSFKSDFLASTNDHLITPPLSLKKDKNSDTSKIVSDNVSEGYSKNSLLVNEEVKNSIKELSQILHLVEGEKITNPETKVVSLRKQFIDLCLQILKIIFEKFLKDLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6R7</accession>
    <name>A0AAD5U6R7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein with role in RNA processing</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">LSM12</name>
        <name evidence="2" type="ORF">HK099_004801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000035">
        <property type="protein sequence ID" value="KAJ3226491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6R7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047574">
        <property type="entry name" value="AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039683">
        <property type="entry name" value="Lsm12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019181">
        <property type="entry name" value="LSM12_ABD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048478">
        <property type="entry name" value="LSM12_LSM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13542">
        <property type="entry name" value="LSM12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09793">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21166">
        <property type="entry name" value="LSM12_LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00995">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52001">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AD" evidence="1">
        <location>
            <begin position="92"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="21044" checksum="A4D8C9B2869C76AF" modified="2024-05-29" version="1">MNSIVHDDNASPIIGLKVKLITTSDIVYEGLVYAYEPTINLLVLQEIKLTSTSKKKQHNFHLLKLSFIKEILKSTSNNSENSNMKHELIPVTKVNEHIITKREHDALNKIGLNVSDQAQLIFDALSKTLPVKWKDDSILVLDEVLITDPYKVENCKVLIKKNNANNSQAFARVCKVLEGERKRLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6W8</accession>
    <name>A0AAD5U6W8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GMP phosphodiesterase delta subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001095</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000129">
        <property type="protein sequence ID" value="KAJ3223450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6W8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.40">
        <property type="entry name" value="GMP phosphodiesterase, delta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008015">
        <property type="entry name" value="PDED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037036">
        <property type="entry name" value="PDED_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05351">
        <property type="entry name" value="GMP_PDE_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="GMP phosphodiesterase delta subunit" evidence="6">
        <location>
            <begin position="42"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="381" mass="43628" checksum="91007C83AAF70EDC" modified="2024-05-29" version="1">MGNLTLLNMKISDFETKKVYWEEDWADIVEEKTRNNNKSDNIPESTNELEHIVASDQENMIPCEILSGNTIIETLFFDDEELINSYTVKQIPILGHPYTTSINPKSLKNTNQFFKNTLNLNRHYKKYSVSVHKQGTPGSSHPDGSPKSGLQQKTIMFQLKVFIATGVITMLALYIISDTHEKYAGTLGLFPIPNDVSIVFVVNSPGVDSNSKCLDVAKEFGFEYLSVNDILNTEQNNPDSDYAEVINAYKSKGLNVPTDVLIILLHRLLNFSYSRKFLIDGFPRNLEEALKFENEVLKSKLIVHFSCPEEERLKEFLIKESKNGKKSTVMESFKKKLKEYKDTTSPLFEHYTKLNKLEQFSCNQSKDEFKNEIAEVFKTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6X7</accession>
    <name>A0AAD5U6X7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6X7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="287" mass="32204" checksum="F077A03BAB1C27C2" modified="2024-05-29" version="1">MSNEGTSALFPGLHVESFQWGMLMSCTLVNLIYALKYAFMHKTGKLPFFIQLSCYYFTDYTTKESIVFGVFMAIFDTLTKMLLVWYINVRLEVIASVNSRMNTLRKLFVFAGLATSILSNVLNWLPTWLGYELPGLTHEIAMAIYLVADIIIAGQDIIVGILFVGKISNSENFMQGLEYWKKVRELKVVSIILMEGIDGATWAIYATYFSFKATLTAYSLELLVKFCVNRSKRSDRAKSEGSLSPRKGSKGFSSGDLTKSGKVVKSNDTLPKTQDTRELGLGEMDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Z3</accession>
    <name>A0AAD5U6Z3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_004515</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
            <orientation evidence="1 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the complex I NDUFA13 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Z3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009346">
        <property type="entry name" value="GRIM-19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06212">
        <property type="entry name" value="GRIM-19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3226634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="21983" checksum="65498468BF7877D2" modified="2024-05-29" version="1">MPSYSQDLPPEGGFPTSIRYQRYIPKRGPSGFTLFVASFAIMGYGWYWVLESNNERRELSREKAWARIHLVPLLQAETDRDIVRRLEAAKKREQVIIDNQAPTVKEQRNFQALDLKAKTPGVGRYGGYDPKQAQPVYHTDRYVAPTFLLLPKEKIMNSQWWRGSKLFLKNPAYHERDDFSSKLEEKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U706</accession>
    <name>A0AAD5U706_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000904</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000123">
        <property type="protein sequence ID" value="KAJ3223612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U706"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033646">
        <property type="entry name" value="CLU-central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025697">
        <property type="entry name" value="CLU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027523">
        <property type="entry name" value="CLU_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12601:SF6">
        <property type="entry name" value="CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12601">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13236">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12807">
        <property type="entry name" value="eIF3_p135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51823">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Clu" evidence="4">
        <location>
            <begin position="274"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1032"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1032"/>
            <end position="1052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1226" mass="139037" checksum="11B3216C2D01379C" modified="2024-05-29" version="1">MAVSKRNIIKQGFIFKRGGSSILSHWKQKFLVLSTSFDAEKNKFNTLLTVYDKRDQLLPPKNEINFSECSVILETKSMDKKINIGPKNNKYFFALTVNGVNKKKVIGNDLRLFLFSTASRSDCEEWIRVLEKCLPKENCYNVQNQRDLINSNNKGLQKVHNLSNSSYTLPRSRSNTNQDYNSDAVSTYSDDSCFTNSDRRSMRSRSCSEINADASPINCERKSLYSAIETMSFCSEPVLTFEELNEMGVRNSNYLHNQIAKSESNKKKGITKGYDSLIHSLIGKQTAFHTEINGSDNWHQKFQKILSIKLENEEMILKRDIMMVEVAGNFKEKAVEQAQKIIDNLHMAQSCKKVFSFPRGVWAGTFNGISYQFIANYDDSTPEQITYAEIRTSQELLGLNSIISTNSGLSVELIINVDYKGFRIVCVPEVYESLNLMQDLIKEHPIILDEANFEKILYSGKILNLKPHFVMLKDNRRVLVPLSTGIQAVKSSSNVESHIALKRMYETFPLDYCNVEDSKQKTTPLLFSKRPSPVRRLRPEFVRSYPHQLCSDALTEWCAHEKHDRDQNDLEVVRAGRFLQEVWIPSFVKKLDELEIRPIDSRTLGLEMHRAGVNVRYLGLIYRLSKIPFIKDMCAIEMIARAFKGIFKCKIRTALLNFRSVGATSIEDQMKEYPVSMFNWLLGKGSKSEKCGVLFDDNVNYTFDNQDNGYNPLNKKDFLSFDVKVKQIGGNSTQTPINEETMNSIISPPEEILAYYLSRHFKSLGKNSKLQKNEDSAQSLTEISSFYNSTGRHEEAKAYANSALGAARKDTCLHSFALAQIIETQCGLQTNSLTIPDASILQLYKKSLQTAEYHWGTSHPLLMGLHDRLSAVFLKANLPKQALEYHLLSLDICFKSLGKNHIVTAGILLSLNNETEQAIKKFNEARHIYQALDADRTLISEVYFHLASALAARGDLDGAILNAKQSKKFREQSLGQYEVRTVETYQLLANLLLANYHNYTGVLTPQIKVNYTEAISCLEKIFRFVKNNKNGRNSRSGFGTSGRNTPSISGRSTPVRPKTHNRSQSLVSQISAKNSNTLNNRFLSGGGTSAHIGGPFFTAPFSPTPTFEKNLIHRLTKKIVKLKLDLIENKQHQEKIRILRQKIKELKARNAAEFIDDANYDDDDVNSPFHNFTAEEAKDVIIKLAAVSPSIYLDGILMRIEEEDETALSEMMIVLQLTESDTVGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U763</accession>
    <name>A0AAD5U763_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003323</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U763"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051727">
        <property type="entry name" value="DnaJ_C3_Co-chaperones"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140:SF2">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="288"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="511"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="737" mass="84812" checksum="24D188D58DA07AD6" modified="2024-05-29" version="1">MEQCLSGRCKFKVYGYHLMKGGAEVTFMVREKYAKNLKNFPILLYQYSMVEKFFNSKNKSLVTFAEYNVRTLEEILSSQENLKYEYILLTISSAALRSNDGGWIKDLVQKTEAKNLITFTPGKEDVELLMNICGGVENLNFASGFITIISYSAPLEKESFSPFEVKKTDNSQDCFAYLAPSSENIQYYGKKTDVGYTSIEKFSSLFNKGGLKSSATHVELYKNKKIEPPAPILIAQSVITPLLMALESVDWKFLNLKNNEKNVLHLLVKAVGELLTIEINKNSSLEEVDIRMKRADCYLKLGNLESAAGDYLRASKIKPDNTLALLQLSKVRLSLGETGDAITSLKECLKFDIDHKECKKSFKELKKFDKEFNKVQETFKKNMFRSVLKLIEGEGDSVEQKKKTGLIYKVKELNIGGNKLKSLMELVCRSKFGVSNSNDEDTLKSCQEVLNLDADNVEALIIKADISMKNENYEEAMRDYKKAHEVSGGDHRAQEGYNKAQRLLKQQGQKNYYKVLGVERNASKKQIKKAFRTLAKIHHPDKQPASEKEKATKKYSEINEAYEVLMDDEKRQKFDNGEDPNDQSQQFNQPNFHQFFQGGVFRETDQFGYALSFSKYSNIERSRNSVVKQQLQTYLEIRMIYPSNPLIIGQLSKAIDLRRDFRCIRKGLKRRWWYLRKLRDSLEHNPFVTRFYINHAKVVEENYFGDTSVFESVPTALNNCFHSLNNFERDLNDILVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7B6</accession>
    <name>A0AAD5U7B6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7B6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019399">
        <property type="entry name" value="Parkin_co-regulated_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207:SF2">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21207">
        <property type="entry name" value="PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10274">
        <property type="entry name" value="ParcG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042115376" evidence="2">
        <location>
            <begin position="17"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="509" mass="53714" checksum="8941BDD1E2624906" modified="2024-05-29" version="1">MFSKLVAVCLLSLAVASPTPGSQSNTISMTGNNASGSQVQKASITGNTASNQFNGINQSGNSAFSQSNSAFIGGNNAALQTNQIQQANNNAVFQNNAAAIQGNSAFNQKNDIAQTGNFAHVNQQNTASVLGNSASNLQLNNVNIAANWAKNDASSVATVAGNHAGFAQSNTANVNANHADNNQNNVGIIAQNGAGKGGQNNNCGINGNDPTNQNNACEITDNKTGGNQQNGISVTGNFNSDSQTNSGLISGNQAAGNQDNFGQIAGNHGGASQVNKLGFFNNKAGGNQNTGANVSGNTALWKQFISMTGISKGAGGYFAPKQSSPPKAGAFAARVVAEKGVTRKHHHSHNSHPFAHHPNSHKSVNDSSASSGFRKLYDRGDFPISVNHDTKGNKINWKVDIEKLDYHHYLPLFFSGLCETEEPYAFLARQGIHDLLDRGGQKILPVVPQLIIPIKINLGDGIYYSQQKRENIGDLIQETLEKFELTGGEDAFINIKYMVPTYESVLSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7J9</accession>
    <name>A0AAD5U7J9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Malignant T-cell-amplified sequence 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MCTS1</name>
        <name evidence="6" type="ORF">HK099_001942</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000160">
        <property type="protein sequence ID" value="KAJ3222774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7J9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11609">
        <property type="entry name" value="MCT1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21155">
        <property type="entry name" value="PUA_MCTS-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04514">
        <property type="entry name" value="Taspase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016437">
        <property type="entry name" value="MCT-1/Tma20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041366">
        <property type="entry name" value="Pre-PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037464">
        <property type="entry name" value="Taspase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22798:SF0">
        <property type="entry name" value="MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22798">
        <property type="entry name" value="MCT-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17832">
        <property type="entry name" value="Pre-PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PUA" evidence="5">
        <location>
            <begin position="93"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="4">
        <location>
            <begin position="341"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="534" mass="58991" checksum="3F17CC910A11F36F" modified="2024-05-29" version="1">MLKKFTVKDDVSSKSKVKSSVQRTIRSKILAQYPLLEPYADELLPKKDPLFLVKCKEQLNLVSINNRVLFFNYYDGPYFPHLKLLHEFPDILPHLQVDKGAIKFVLQGANVMCPGLTSKGARLTEENIETDRVVAIMAEDKEHALGLGLTKMSTNDMKSINKGAGSHSIKKEKYYNTLSKKACIEGMKILKLNEEDSLINAITRAIQVLGSNLNRGGKVECDASMMCGRTGAFGAVGASDCLRNPIKFASVILRREKVGSVGHKFGLIPPMLICGSNGVKEYLEFVNENCSVEAKNVTEVVNNEVLVTSERLARFKEYTDLLLNDAMSESGFFPSEDLTEDTVGAIAMDLSGNVFSGVSSGGIWLKHPGRIGEAAVFGAGCWSENHLKNGSNLYGFATSATGAGEMIIRSQFSSALADSVMNMRTLTSQLKPIATETVPDHLKNFVKEKVFKQSLKFKEKNLGAIFLKSNFNLNQNFAELEFWFLHSTKSLAFGYIFKDDLKPTCVISRKSSTGHEDFIKVGCEVKCLRIAKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7K9</accession>
    <name>A0AAD5U7K9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000744</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000119">
        <property type="protein sequence ID" value="KAJ3223724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7K9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019411">
        <property type="entry name" value="MMM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF0">
        <property type="entry name" value="SMP-LTD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10296">
        <property type="entry name" value="MMM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="9">
        <location>
            <begin position="57"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3223724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="375" mass="42852" checksum="AC9EB14D475D9933" modified="2024-05-29" version="1">MSFLTGIFVSASVLYLVSKLFAKNRIKQLQKVQVFCPDNIPEKLKKYIEQTVSEDHKPETSEWLNLMVARYFLEFRRFSILEEEYINWINETLNASVEGALFSKLDVTDIEFGNSAPRIESVRIIKCGPQKDLAVETEMEIVWDGNATISLDLQIFGGTVYPSLVRLTHLRSKVNLRVPSKMSAYKVDVIFGRFEGEDLAEFTIDINKKGDNIIEENLSKVLSKLLQKTAHDFTTGVFTFDIPVISTVKMDESVPEVRHPPLQRVPSTKDKVKEKLKSAFACFSISIRNLYKYLSRLKQQTALRQLMPAPKELEAKKKSATASRCKVVEKVKNPITFSLNLSFPPKFVAEFRIDATIKIETEKFINMIHSKDIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7N1</accession>
    <name>A0AAD5U7N1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">T-cell immunomodulatory protein TIP C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_006748</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000060">
        <property type="protein sequence ID" value="KAJ3225475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7N1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057089">
        <property type="entry name" value="C2_TIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024881">
        <property type="entry name" value="Tip"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13412:SF0">
        <property type="entry name" value="T-CELL IMMUNOMODULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13412">
        <property type="entry name" value="T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23122">
        <property type="entry name" value="C2_ITFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041943361" description="T-cell immunomodulatory protein TIP C2 domain-containing protein" evidence="8">
        <location>
            <begin position="19"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="T-cell immunomodulatory protein TIP C2" evidence="9">
        <location>
            <begin position="518"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3225475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="588" mass="67329" checksum="2C6242998FA34D79" modified="2024-05-29" version="1">MFCLYTLLSLLILIGTYSSIKPSKFVQYLGFNEVDVNLNFGSVAAFGDFNNDKMNDLFLFNQDQTSVFVHIWNHKNFEFQLLPKTEINYTLNNIKLKIVNVIPGDFNYDGKLDVLIYCQKFQSASTNLFGMEQIDNVNPDKTFMRIFYGNSVDAFEQSTYKDLENSTLSQPLLFDFYGIMKPSLLGYSDLTKNLSLWNVFEAKNNSFQGITFNGTKPLCKFSHPNSNAFIDLDGDCLADLFFTCQDSENSQQYMQIWLNRKEDGFVFSKELQLPKGAGRISFSDMDGDGTMDIVFPTCVDNICQINVAYNKQIPICSINIHSNCRKKENLCISDENFEFNFDLNSELYSVFSLPNQDTESLVIEDELFFDKNTIPLRIGDFNLDGFPDLIIITKLNSNPKKQKLNLLTSIPCNSDICNEKEIRNFRRKFELLTVGADKLNNYFGEFQEALFQGAFFDLDEDGSLDLIIFYKNLKNNSFGLKFFINNFFNDAFFLKSLVLNGVCPSWCPDGERVPNTKPYGVNYVGSTLKFQVAGTSGETRARIISQLPQTSYHSLQTPYNLFGLGRTNNYIENLFIGVSRHQVCWPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7R2</accession>
    <name>A0AAD5U7R2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001132</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7R2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050367">
        <property type="entry name" value="APC_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770">
        <property type="entry name" value="AMINO ACID TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770:SF7">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="509"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="539"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="574"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="601"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="6">
        <location>
            <begin position="195"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="687" mass="77371" checksum="4D76127CB00B94BA" modified="2024-05-29" version="1">MENNAGSRSDIDTINSKISHVEKGKRRKFSSHNLLEEVLDNEYGKYEEQNDKIVSIENLIEHEGIHFFGDIFHYEEEIKINNGIQEKVYSVKRLNADTESKEVPELKNSNSNLSSKDAGIRASITSANGVAVIAGKKGSWWEDYKKRVIYCNDYPDDLVTIKDVMKEYFNRRKLPKFKANIYHLFGLGVASVISGEFAGWSTGLATAGYYGFCVASLIASAMFLFLAGNLAEMSGAMPVVGGSFAYARLIVNDSFGFLLGHSENLEYLSFITLLTVSFGEYCAEFFHIDHYTWAPLLWLLFLIPGTYIVAYHNKTLWNMMFAGSVVCLLQIAGFSLFAIKYIDEKYILEGTSKHVAHHNIDKYWGLGLGGILQALHSTSWWYTGFECLTLAAHETADPVVKNVTKSLYLCWGALSLCAVLLTLTNVLVPPGMGTIISSIYPMVESILAITKIESKAHYFILFQLPALWINLLAMLWCATRQTWALSRAGYIPKLLSITSVYENRVPRRSLYFVIVYVIWMTFTVHYLHLEGEDLHPVDALLALCVISATVFYVGVSIVYLYFSMRYKAVPRPYVSPFGKTGAWFVIIVGCLLILAKIGLSHIFQLTVAIYCIKMFISAIFYYGHAKMHLLPTEEAITHILWQAKEKNEKKIPKFIPKILVRNRENTGKSAEGNTGTHSLKVAELNPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7V4</accession>
    <name>A0AAD5U7V4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7V4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030676">
        <property type="entry name" value="CitT-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42826">
        <property type="entry name" value="DICARBOXYLATE TRANSPORTER 2.1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="518" mass="57034" checksum="CB029D75505EEFAB" modified="2024-05-29" version="1">MNTLANETSLLLPQENTENANTKRSSKFLILLNFIKSSFYEITIIIFSFILWNSEIDGISKSGVHILAAFICVILFLLFSAYPIATVVTPALLSTKFFPNEYLLMKIQHVFLTLTQSFKCETLNGLKVDCVECGIINKMGEVNQCDGLKSGFDVALSGFSKQLSWLVLLAFHIGKAVEITNLGKRISLIFVRYLGNSYLGLGYAIFATEVILSAFIPSNTARGGGIVMPVVISVAKLFNSTPTNNAKIGQFLILCGNHANFLTSSFFLTSTIGNPLIANYSWQILGIEFGFLNWAKGSLFPGIVAIVVLVPLFAYLTEIIDFNGNYSDPPETSINASCHAKETLKEMGPMSNKEITLCSILFLCLSLWVTNKETSLPEGLIAFIGLTLLILSNTISWSHVIENASGSSNKYYIKPFNFIIAWDSFYWLSGMILLSEQLNDHGITTLIGEKSTNLIRVLFNGNFPVFFSVILGILYTLTIITGHTVALCVTFMSAAKKLNCPLNLIVPILGFSKISKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Y4</accession>
    <name>A0AAD5U7Y4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA hydratase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ECHS1</name>
        <name evidence="4" type="ORF">HK099_000052</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Y4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="293" mass="32264" checksum="77CC7FD5A192509A" modified="2024-05-29" version="1">MFHPTRRSFTTSSFLRSLKYENITVENRGKVALVTLNRPKQLNALCSPLFKELNDAMENIQADSKIGAIVLTGSQKAFAAGADIKEMSTQTFIDNYKSNFIADWTKITTVRKPIIAAVNGFALGGGCELAMMCDIIYAGEEAKFGQPEIKLGTIPGAGGTQRFTNHIFSNTENRNFVFLKRLTHAVGKSKAMEMVLTGSLISAQEALSSGLVAKVFPSDKLVEEAVKTAEIISSYSNPIVMMCKEAVNKAFELSLNEGLHLERRLFHATFATADRKEGMSAFVEKRKAKFEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U897</accession>
    <name>A0AAD5U897_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U897"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="233" mass="26905" checksum="CA1FE9F292BA7720" modified="2024-05-29" version="1">MASDDDLKKRFEKLKCDNVKHRDLPTEEELVKRLTNLTGRDVIPKEISEHKKILNVNEFNDHDLNSLLNDKILLDDLDILYQKDYQLQTPNTPLPTEAISPKSKRYVDFTDLVLVSPKLATQPIDQEAIKLIEEAQEEVRLEKKYGEINNDEAFEERFNNLFKNDDTLSAVDTKVKKKVSLKNLGRPPKAPDVKDFLEENEDCSSWCCICNEDADVRCEDCDDGNYIKNLSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8B1</accession>
    <name>A0AAD5U8B1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="12">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">HK099_004296</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="17">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="19">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="18">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8B1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="20" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="21">
        <location>
            <begin position="27"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="20">
        <location>
            <begin position="599"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3228303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="723" mass="83005" checksum="25501C31D71635EC" modified="2024-05-29" version="1">MENSTIEQKKLTGWELYEKLNKPKFIMAPMVDQSEYAWRLLCRRYNTNLCYSPMLNAKLFCESVTYREQYLSTGLNDYPLVIQFCANNPEYLLKAALLVQDLCVAVDINLGCPQHIAKRGRYGSFLMEDPQLISELVKILHLNLKIPVTCKIRIFPDINKTLDYAKMLQDSGCQILTVHGRTRDQKGHKTGLADWKAIKRVKEALSIPVFANGNILYYEDIENCLKETGVDGVMAAEGNLYNPALFANIYPHITTISREYLNIVKDNPKSASMSMVRAHLFKMFNPCLKTLTDLRSNLAKVNNLDDFFAIVDKFEEALKPHVTEFNFDLLDVDENGFKKLPIYVCQPYFRPPLVENKRKEKILEDELKKSTVKNNTNDNVFINENVLVAETVKKTTGCDIATKDTSKDEIENIVAMESKDDAEAVSLKRKKDESYIESEINLEKSVLRKSLVNSSKKIKRVQNDGRDKILKCVQYTAKFLVSQNLVKSEDKIKKLKNLASQFSITRKILRLIHFLDPLEKLMEIDLKDLSLRSSSVDSKASFIQNQLKFFGAINCLVGFTQDVIDDFICLSKLGALEKSWQSYGDLSDRLWLTTIHFDLLEAVFQYKKLNSNLKSLERQIVEENEHCHDQKTNSSTVNEKKINQFFLSKENNNIQNLKIYAEAKDKLFLQKTSILKLIMDLIFCSYDVFGFEKNLGLSETWQLTAALISGFLSTYKLAKKTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8P5</accession>
    <name>A0AAD5U8P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pre-mRNA 3-end-processing factor fip1l1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FIP1L1</name>
        <name evidence="7" type="ORF">HK099_001917</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007854">
        <property type="entry name" value="Fip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051187">
        <property type="entry name" value="Pre-mRNA_3'-end_processing_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484">
        <property type="entry name" value="FIP1-LIKE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484:SF0">
        <property type="entry name" value="PRE-MRNA 3'-END-PROCESSING FACTOR FIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05182">
        <property type="entry name" value="Fip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA polyadenylation factor Fip1" evidence="6">
        <location>
            <begin position="122"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="271"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="316" mass="35012" checksum="9E88F8F0CF146ABE" modified="2024-05-29" version="1">MEEEEDIDNDLYTKDTAEDPNKIEGNFVDTQPLTATELNSQEVDENEPEKVEGNDSSGNRNSLVLNNVLINNQKPAALVKTATTQKQKEGGEKQGTVSQGVYNKPGLDLNAVGVLNGKEIFEVDLEGIEDKPWREAGVDPTDYFNYGFNEITWKMYSQRQKQMRGHGGLRNPADWNTGMDHMGIMGPALMQMNPQIQQQQLQHQLQQQQQQQMMQQQMMMGQVGFRPGGFANAYQQPMLANPMMGGNVMGGNSMANNNINQQRNINAQVLGKRPRESTEGDGGVIDLSAKGSKGTKSSKESTVDQGMVKMKSILII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U913</accession>
    <name>A0AAD5U913_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">N-alpha-acetyltransferase 35 NatC auxiliary subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NAA35</name>
        <name evidence="6" type="ORF">HK099_006524</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAK10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U913"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057983">
        <property type="entry name" value="NAA35-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057982">
        <property type="entry name" value="TPR_NAA35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04112">
        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25789">
        <property type="entry name" value="TPR_NAA35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAA35-like N-terminal" evidence="4">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="NAA35-like TPR repeats" evidence="5">
        <location>
            <begin position="284"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="687" mass="80340" checksum="C3E3B90B26D46273" modified="2024-05-29" version="1">MLSIKDSLQNSCKQLDIGELILADNFELYDAMSCIEIMNPKMDTGLQQNFTFSPNLLLDGQKRISFIDHLFAKEMQFLNGNLLSQTIYTCYLFHENFKMQPNSLQDENLHEILNNFKAASKLFVNFTNEIIVKAVVYHEEDFQFESTGLDLTGFPNLNSLKKLFAKSLAKINTKNNYDALLINRIQMKLDWLQLMAQLNCDDYKSAKVTLSKLITEFQKVKNTLELEDITDYFDHRITLKTFANSAPRPILNCSTAAEFESFQLILDDFEIILNFYSTLVAKFDLKELHLFLHYFSRKTPASNCFVHSVLMNLILYFLRNIKFKDYLKDSIKKLTSPLYTMIKIPEAAKEKVDFALTNLEIAYSNYITVFCKNSARTSRNLLKIVKIYEQLQQETETVDDEIHELVLKTYNLKIPVRYDISCWIYNEKLFMLTEYFEKGFRLEVYNDYELPMIFWYIIFIQEMHCNHLNLIENMYEQSASGIENLHLKSLQLFLNVKLELRKSLLLILVVLEKKKLLKKPKLVNTLSNGDDVTENFNLYKEKLHFENRFKIFNLLGSPVKMGFNQYVDDMEERKKLSIGTLFELSLQGLQKAITYLDPLLESAINNKSNHFQFLEYKKELISLKKVCIANQVKLNLILNNSKLNGLQVKGNKKKSKINKFGNLDIVQLKFESVDWNYSLDFPVINIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9C6</accession>
    <name>A0AAD5U9C6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000044">
        <property type="protein sequence ID" value="KAJ3226105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9C6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019903">
        <property type="term" value="F:protein phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="589"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="722"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="741" mass="84277" checksum="6CE06A3551D34D4A" modified="2024-05-29" version="1">MFWRFGFHNSAAIDSTLEKEGLTLQDLFEEEDLLQECKSHNNKLIDYLCKVDVLKQLTDIMLIKNKPPSDVIEEEEERNKRYKYAYYACEVLCCEVFAICDAFVSNIDLLAELWKILESPPPLDIAQISYFAKANMVFLEKKPVQMINYIKSKPSILSNLLNHISNSGVSGLLLKLISIEEVPEAHGIIEWLRNENLIIMLLDRFNPELDSLINDLASQLILDIIAVSYQTSSQIELALMDPTQVVPAIGGNVLIEQLKSEHVINKLVDYMVSEKNSRNNHVLINGINIIIELMRRYCSEIEQAEYQQHHHQIQTHKFSSNPVSLEKLKALATDPNGLLRVLGTRINEFIHLLSSSRTNKEPVMTSIGLNVPLGCERLKICELFAEILHLQYLYTSSPLFDKLILTSLGKNGTTNDVNVADELVSISESFVNSKILPICLDLFFKFPWNNFLHSVVYDMIAKIFVDKNNTYTFFTMAANTSVISTEKKHPIIEEKMMFIKKVVRTLVISIYQDGQLTTKITNAQRQNDYELEQPKGVRLGYMGHLTYISEEVCKLMEKCSADLKDDLNSYFQQSTWEDYLSGVYRETKERDHQALGGERPNAPPTSNVIPGVTGIQNGVIVDELNPTQQNQVLKKNLGQNAEDSDDEEDLDKGEICLADGDFASDQFARYLCQQIVNDFPTGFSFDEEEEEADADDDLAEWKTGLVLDTISGFEMDQKFPERISSLDTSDVESKFSEEKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9D5</accession>
    <name>A0AAD5U9D5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="9">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">TOR1_5</name>
        <name evidence="14" type="ORF">HK099_005222</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="12">
        <location>
            <begin position="1537"/>
            <end position="2100"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="11">
        <location>
            <begin position="2288"/>
            <end position="2618"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="13">
        <location>
            <begin position="2659"/>
            <end position="2691"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3228212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2696" mass="310029" checksum="D2EB18F00B7FBA45" modified="2024-05-29" version="1">MSKYIGELARYLLNAFPNDDSAAWVRKNSKVRLAIGNGLRPDIWEQFKSRFNIREIGEFYAATEGNLALFNHNTSVIGVGAVGKQGPLLAKFMGLKLVKFNHDTETPIRGKDGFCIECDANESGELLAPVITGDVSREFKGYLDEKATAKKLIKDVVVKGDTYFRSGDLLKKDLRGFYYFVDRIGDTFRWKGENVSTMEVAEAISKYPGVGEANVYGIQIPGFDGQPPMVSITPRENEKLDLSNLYSFLKPKLPSYALPLMDITGTFKHQKVELRKQGCDPTKITNEDLFWLNNGTYINFEYPVLELDAMLINESNQKAILNNIINDLRHKNDALKRKAADELIEIISTLYLEISNESFNKFINLLYKRIFELLNSDINDKISGIFALDKLIDFEGEKKSLKISRISKYLSMIFPHPDHRLSSYASIALGHLALLDQLSDFIEYEFKRAFQWLQQSDRSESKRYAAVLIIKELTINAPLIAAPHLLRILELIWIPFKDKSLIVREGSADALCACLGLINQNSNYRTITDFYNSIYENISFILKEKKDTDNLQGGFLALNEILKQRTFFTNVKYSKISELVMKFLEKDHSKDKLIKQSIFEVIPSLAAFDKENFAKNDLFNCMNFLLLQMEKDRDISPIYLSIGKISLAVGSFISPYLSQVLAQIKQGLTIGKRNNYSAQVENSIFLCIRSLSKACGPALTKYMHELLNNMFTNGLNQQLILTLRDLVQYIPPLLSSIQEHLLAWISFSLNGKKLRRSGFYRDDYSIILALNTLYSFDFSGQNYYRLLTECSFPFTDDDNINIRDSSISTSVKLLTLDPICYKTDEESMNKVEKVIQRLLTLGVTDLEPQIRIKIFFNLNETFDYHLAQPYNIRILLMALNDEVFKVRELAIEIFGRICVFDSNLLSPTFKKILLRYLNELAASTSRSKKEETAKLLKVLIISAKEIIIPYIDDILKNLLSLLRIEKNNSILMECCGELSKFGEKKVLKYINVLVPILIENLEDSTSTAKRSSALNVLAQLCYNTSFIVEPLIKYPQLLTILIKLLSADSNSAVQKNVIRIFGVLGAVDPYTHQVASQMYEKKENVTVSNLLPLSNALYYHSVAIVDEPPLNYLHSITIQTITFIFKVSGSECVQFLSLVIPSYLKTMKNCPSNLLESYFNQLGLLVSTVNREIAPYIKEILKITNEFFSTVNDDLNLMLSIFRLLESLKKIFDYDFKIYLPLILKDLLKVFEWDKNSNRFLSQKVLNLFSTFGCTLNEYLHLIIPTMIGLIEQSEVPIPFKECVLSTVSKLCEVLNFSEVASRIIHPILRLFETCNYYELASENATQDGTLALTSKTSMNRLKILGMNALCSLALSLKIDFLALKKYNMRHNNYESIIKKILDNEDIEYEIQISGQTATIQTLEEEIFIAEYQKKLPVNQLNLKKSWDCSQVSSKEGFINWFYRFVNELLKESPVQILRACSGLAQQHRGLAKDLFNSAFVSCWSELYDQFQDELVRSLETALTSVNSPSEIQYALLKLSEFMEQNGKPLPIARLDTLATFSTKTQSLAKALHYTELDLLDKFTLSPCDVVNDSIKILLDNLVFIHKELQQPDCEAGILTFANDYHRFHGCDIQFQSCKILRNYSEVANHFEKLNKWEESLLNYEKKYIEDPANVVATTGMIRCLQKLGEWEILADLAKKNWDKFNLDLQVYIAPTCCAAAWDVKDWKMLEIYLSAIPAEQNANSSFFNALLCIVKNSFAKSQSFIEKTRELISSELSSLLNDSYSRAYPLIVRAQILSELEEIIEYKKLDDNHNRRLLIRNNWSKRLNGCSKDVDVWQKIFKVRSIVLTPRDDIKTGIKFANLCRKNGKLNLSAKALKKLLCSETDDLYNLNIEKNAPKVVYTVLRHIWVSGGQLHALKELKRFTTFLEEAAQNHNFKNQKVLAKSYHLLGTWNTELQHNKWNETAIAEILVLYDRACKLLPNYKMHHTFAVANYQALSFYEKMKNNGFTNKQLIPTVVASIIGFFKAISLSEGNSLQDVLRLLTLWFKYGDKEEVNDSVSEGIKSVSTDTWLQVIPQLIARIYTPIGIVRRLVHQLFFDIGKFHPQALVYSVTVASKSNEISRKVAAESIMENLRVLAPSLVEQALIVSRELIRISILWEELWFTGIDFLRFFYNKYIIGIDEASRHYFKFKSIRGMFGVLEPLHQLLKKPETLQEISFSINYGIHLEQANDYCESYKIEKKEEDLVFAWNFYLQVFNGIRKQLPLLRNLDLSYVSPKLMKLTDLLVAVPGTYCGTGHEVVTISSFDADLTILLTKNRPRKLKLLGSDGKEYCFLLKGNEDLRLDERVMQLFGLVNTLLKRDSETFHRHLSIQKYAVIPLNHQSGLLRWITDCDTIHSLIEKYRKERAIDVSLEQHIVEKFCIMQKLEIFSEAEKLSTGHDLYKILWLTSKNSEHWLERRNNFSKTLAVMSMDWVTDICEFSLYIIDIYSFFRNNLMIERSTGVVIHIDFGDCFEVAMQREKYAEKVPFRYLTIFHIISKQNRRLTRMLYNVEITGVEGTFRITCEQTMRVLRENKESLMAVLEAFIYDPLINWFKEDLVNGKLKYIFPNFVIVEVVKEGLWNNDEEKNDAFSRSFPHTYRKICDEKKSVDLTNSRALGVIKRVSNKLSGRDFAENSTLGVNCQVNKLIRSAVLLENLCQAWTGWQPVRKIFMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAL9</accession>
    <name>A0AAD5UAL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAL9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038885">
        <property type="entry name" value="PLB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325:SF31">
        <property type="entry name" value="GH22081P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325">
        <property type="entry name" value="PHOSPHOLIPASE B, PLB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041975736" evidence="1">
        <location>
            <begin position="19"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="326" mass="37172" checksum="7B2A70E7EC779201" modified="2024-05-29" version="1">MNFLITILTLLKLITTWQIPFLKEVNDESEELKVSNIKVVAALGDSITAGFGAKDSGWNPPTTKSFIENRGVSFSIGGDKNFTTLPNLIRNYNPNLVGFSTGEHLAELCYGVVCPPQYYIEDYLNMAQSGSKLINLFAQDLCGACLINSLSPDLFELGLREILYDLSTIPNTIVNVQALFPVSQIYDLTKDDVYCLKLRNRGLSFECFCAFNDGEDGRKKMDEYWVQYNRVIEKVVTEFKNQREREKKFHVLFDPSNVGVDIRRWNSKNFISKIDCFHPSVEAHKAMAISLWNNLFLDSSKKKKNIDPENFGEIYIPNEQSRIKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAU8</accession>
    <name>A0AAD5UAU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein eif1ad</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EIF1AD</name>
        <name evidence="5" type="ORF">HK099_003739</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EIF1AD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000025">
        <property type="protein sequence ID" value="KAJ3226947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAU8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039294">
        <property type="entry name" value="EIF1AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641:SF0">
        <property type="entry name" value="RNA-BINDING PROTEIN EIF1AD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21641">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="463"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="561" mass="63696" checksum="3DF86F6EEE58344B" modified="2024-05-29" version="1">MTNYKKAHKKKQTEEEFPLPTPTQLIAKVTEIRGGNLFLTKTENDTESLTSLPTKYNKLLWVKKNNYLIIEPNTEKTNKIDSEIVHVLFREQIKHIKKCNKWPIVFADKGELENEKLDDDYNNSDDIFKNNNRMDYSSSDDEDSSCGEDFSFNSTKIIISSIDSVSNGKDFYSSIKRDSDKFFVDDEKRAILANGEPANYLSVTNSGFLVPSSLLAEGTYNQTVLGVGFVPTCRSHKTTGYITINETGMEILKGFTFPDSGYTIMPASVHSNSFVYPKLTVFQQSRLEVVSQGLNSNKSLIIDALLLTSSANKDQINDDWYPEGEALNSNEDNKINSIWAISCKFQSGIFQVSLYQSADEFYANSKNNALLVESEIFHSNSISKHFSTMPLSHLSTDDMLKIDWLDETALPNEWRNKDYVVSRASFQNYLMRAAAIYLGASVNPDFKETYIKQTEGLKTKQEFFIVFSTLEIIITPIILCLLSLLVFFSTLNKKFTLTATEKSLLKRDHFFFMSLDKVLEHFGDGKHIIELIDSNSISKNLTGKQIGSNESLMEEVKEYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBP3</accession>
    <name>A0AAD5UBP3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TOA2</name>
        <name evidence="11" type="ORF">HK099_000801</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TFIIA subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBP3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10014">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10145">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.190:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.190">
        <property type="entry name" value="Transcription factor IIA gamma subunit, alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009083">
        <property type="entry name" value="TFIIA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003194">
        <property type="entry name" value="TFIIA_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015871">
        <property type="entry name" value="TFIIA_gsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015872">
        <property type="entry name" value="TFIIA_gsu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10966">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02751">
        <property type="entry name" value="TFIIA_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02268">
        <property type="entry name" value="TFIIA_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009415">
        <property type="entry name" value="Hum_TFIIA_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit N-terminal" evidence="9">
        <location>
            <begin position="22"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor IIA gamma subunit C-terminal" evidence="10">
        <location>
            <begin position="78"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="125" mass="14086" checksum="F9484D9F816E4CD4" modified="2024-05-29" version="1">MLKVKSTSLCNAKNLMNSETQYQLYRRSSLGSTLTDALDELISSGLMDPQIAMKILTQFDSSISEALRTKIKAKATLKGHLDEYRFCEDVWTFVIDNPTFRFENETVTVEKAKIVACSVKAPEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC81</accession>
    <name>A0AAD5UC81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_004300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC81"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000147">
        <property type="term" value="P:actin cortical patch assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF57">
        <property type="entry name" value="AUXILIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="490"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="494"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3228307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="656" mass="74049" checksum="6E2DCB520B12C198" modified="2024-05-29" version="1">MEELLKVGTILKVNQNICRINSFIAKGGFAQVYSVLLNSTMQKCVLKRIKMDSQIILNSCQNEILYMKQKNQKNIVKYIDSQFFSSSTSHEVYILMELCEGGHLVDYLNNRLSQRLSEFEVLNIFLQICDAVAVLHTFNPPIIHRDLKIENILLNEDHTQFKLCDFGSASNLIIPCGASLSLHEIKLLEDEINRFTTKEYRPPELLDFFQKQGISEKIDIWTTPFEETGKLGILNGRYSIPIYPQYSDNLITLIGSMLTLDPAKRPSIHQIIDFISKMLEMPQIHLKEHLSSTTVPENVKNSGIFPSTPVESIKASLNRNSHPISKTKFNIGEKNFTHINQEIAIPNKNFQNQEIDSNLILRTFQKPSLAQEKNEKDALTGGFLHCNRFNNNEESKFTFVEALNKCNKHDFTSFDDLNNNIDLIFNNKDSLLRSLSKEGKLQNLQLSTATGSSTTSSNSSLCVNANFLESSSAEDAVVCKNKLSSSNELPTGFLNNLPQNLNNSSTSPSKELLKESGNSSPFRSIDTLALNMLTSPYRNENIFSSHSTPLRFENAFSSPTSPYGYSNFQHSPFHIKSSPSPSVRNENTKVTEYSLNKEDVRNLSLNYHVNNQEDDVYMNHFQYSATDKLSPLVDLKSIPTGFLSSPPANSGTVFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS78</accession>
    <name>A0AAD5XS78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">B30.2/SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001163</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001300">
        <property type="protein sequence ID" value="KAJ3204434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS78"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051295">
        <property type="term" value="P:establishment of meiotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051185">
        <property type="entry name" value="ASPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706:SF1">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3204434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="881" mass="101869" checksum="17DFD64007640AA1" modified="2024-05-29" version="1">MRQKTIICGGQKELQYIKDIGVQIQMLSEFSKKKQRLTALKDLTELKNLTSLSQKEDNMNLIGMEAIMAIVDRSSRNQILRTKLMARMSDEKELSTSLQQHKEDFSQFICKRRLAGKKELKEIFQAGPGLVCRYGDLISDASIDTIRTFEYSNMVQLVQDGINCSFLELEDVSSLLSRQIFLSNPKKKTLIIVYPSRLEIELIVEYKKEEDDVETEESMMNRESPESVGQISTEIKQKLKAPVPIPYWTCVYACRGVWGKRLLGKFILKDLCSQAVDQFTRDLKNPLKVQLSCTQLVARILDAVHPTHQLQSSVLASGGMGVTVLKKQAISLGYNVSKESLIAAGIISTGEDFLGSTQHCDPKLGLHILKQVLARLETELRYYFEFSAPDIVDWRVGFCSAIQYPNEYLTYPGELPGTMGFGSDGSIFYNGKVKSYIKLEKEEFSVGMKTWGIIVDFKKCCISFVVCGKEQPIAFGKFSLMFNEKERNEQTELIKNCELIPMISMLTKYDVSPYSEKHQMTFNFGPTFNFQSIVATPFNKNVKYKEFDCEDSNIVGNLSEDVKDKTSVEDEEKNFMSIEKTNYKAAVSSFEMKSFSRFPPSIYRRSIACMKIQRAWRRYQGKIIRNTLRALQFNAASIIQNMARKKLRKIKLMKNLAAAKIQKNWRKKKFVWIALLRCIYQQTIFELHKSASLIQRRYRHWKTFKNSPIAQKYNKRIEGQIEKSVNKIIAWWKPLYKKVSEQKRKTEIHQAAINIQRVYRGWYLRQMLRPDLRQKLSALGASVAKHRKELFKIHSAYVLQNAWRAYIQRRILNEKIKTRNSAGSRIQALWRGFWVRSHTHMRFSYGEAVFLSAVCKALRSCHFIPKMYRCCGIVCPKESNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTC3</accession>
    <name>A0AAD5XTC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nuclear receptor 2C2-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NR2C2AP</name>
        <name evidence="1" type="ORF">HK099_008082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000851">
        <property type="protein sequence ID" value="KAJ3211188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTC3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="175" mass="20415" checksum="572E7DA8BDD6C15C" modified="2024-05-29" version="1">MSNAEETNKKTLSLLKEALKSQQISLKVSSVLNNETKLWGKQNLLDGSEETCWNSDQLSSGSKKSPYLVLDFSNFEIKKVGLNSVKLKLKFQGGFTSSEVEFFFYSEKEWKKFNTFFLFDNNDDQIFTVIKKNEEENLFESFFESKKFKLVFKDPKDFFGRITLYTVDFLADYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUB8</accession>
    <name>A0AAD5XUB8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DisA/LigA helix-hairpin-helix motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006446</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000556">
        <property type="protein sequence ID" value="KAJ3215266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUB8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043240">
        <property type="term" value="C:Fanconi anaemia nuclear complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026985">
        <property type="entry name" value="FAAP24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31786">
        <property type="entry name" value="FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31786:SF2">
        <property type="entry name" value="FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DisA/LigA helix-hairpin-helix motif" evidence="3">
        <location>
            <begin position="29"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="75" mass="8500" checksum="1448372AA301E0C1" modified="2024-05-29" version="1">MVLKANLIEKPKKDDINKLLLNALMSCNGIGEKKAMILLQHFKTLKNICNAEFKELEDVIGSVLATKLIEFFHTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUF5</accession>
    <name>A0AAD5XUF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EPL1</name>
        <name evidence="10" type="ORF">HK099_006184</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000519">
        <property type="protein sequence ID" value="KAJ3215793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUF5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="9">
        <location>
            <begin position="12"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="574"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="596"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="796" mass="91297" checksum="9D84817DC5F9F90D" modified="2024-05-29" version="1">MTNNSHHSGGLRSRKVDFKKGLNVHRQDDLPDLDESNSLNRSNAVIATGVEKEEEEEHHLQVALNSKHTGESHASVYIPTPDATKVNLKNFQQFYKTEFVEPKTLIKFSSQIEDCIGAHYNLDERDMAWLEEEIWANETTDSRKLNEDGFEDIMSHLEMLAKEKLTGECPSLEEFYELVQVHSPQTLELKQYFDKVFSWWKTRRYVERKGKAITPSLVHEEALGVENDPYVCFRRREIKTMRKTRRCDTLSLEKLKKLRDEMKKAREILELVCTREKLRKELLKSEIDVFEARIKVRKMKKILGIATTSQDVENSPEKARRKYNKSNSHAKIKISLKKGDSAIWDKGSSLEPQPIESRIKKRRLTDEKDGVGDFTEYPYIPQLPAHPGHNFWSLQSATSHLDSPDDLTKIQQPLIGRQNLLIRRRVGRGGRIIFDRHYNRNELLNLVGCEKYITKNTDSEEEDTFETKFIKKWKFDCSDEDIEDKIVELEEQARFTMYRAFNLAPGNEAECRSLMNKPSFPEQTTIIPYNHEKRAQLYNQSINQSFHISSLPNNNITKANKKALALSRPSLTALENKDTDSKSDEKVSNVNTATETIKKSNKKDSSSTKKKDIMDPRQSALKNMLQISQKNAAMQSQYAPIQQAPNGANTLILPNPSNNIPILPSTSTISPPKNGQYPLTGQQPIRPNMQFYPNARYPAGAQIPQQQQMFSQNGIPYPQNNIFFQHQQYQQRLLHQQRMFLPQHQFPVVSLPQTQPSINNSSATSAANLLPSAGLTDLEETSLVDGDEILSTLAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUK9</accession>
    <name>A0AAD5XUK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000486">
        <property type="protein sequence ID" value="KAJ3216292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUK9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="223" mass="25539" checksum="69BB535F6F4166C6" modified="2024-05-29" version="1">MYVNKENNTQLNNVNVNSKKAMIKQVLVKKQSFKENALANNKKKSNTNESKENPIKFQSKLNKTTASQSEYNISHTPVNKNSATLKDITKSNLNNATRTPFQQKNLNSLKSTSKVPLTNKSIDHKLKSEDIEIEHIPTKNTNYTPTVETMYPVNLKYNPKLNFIPFYDKKLTDYCKSIGNKPDDPLLGFEEYSNIENENDIFDVLSDLKPLIYTEIVLDSPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUV0</accession>
    <name>A0AAD5XUV0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">28S ribosomal protein S5, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MRPS5</name>
        <name evidence="7" type="ORF">HK099_005602</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000444">
        <property type="protein sequence ID" value="KAJ3217089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUV0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000002">
        <property type="entry name" value="30S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="6">
        <location>
            <begin position="40"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3217089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="21497" checksum="4325879DA21A0950" modified="2024-05-29" version="1" fragment="single">MKRNQSSSSMGQYKTVRSEKLYDSFKESKKTDKPHADKTFLKRLIHVRRIARTTGGGKKRSIWAMVVVGNGNGSAGYGEGRALDSANAVQKATKDAQKNMITIERFDNRTIFTDIDYKFGKVDLKLKTAPAGYGIVANNHIHEVCRCFGIRDISVKIRGSTNPMNVVKGTFEALQTQRSPQEIARVRGKSVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV69</accession>
    <name>A0AAD5XV69_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001280">
        <property type="protein sequence ID" value="KAJ3204637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV69"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="345" mass="39353" checksum="1A1526557F3A6BAC" modified="2024-05-29" version="1">MSKIGHNKFNSTRAKFVSCALLKNDVEISSSSAEFSCFQYTTQTCLTHAIEQFNQGDTLSLKVTVIESVDDISVDYCTLNSILYANWVKFNSLNTNEIELTNGAYTDIPLNSVVVSDPNYSTFVLNKCIVAVKKLGCYNVYFKCTITNTNLENINVGTQISINNKTEFVLGLNNVTQLIPNSVANFFFLTTFFGKNCVVSNVNAIIYKLEDTINYDLVGLNQYGTFHHYAFDSSLFLITFETFYTFFVLETKFLTSGNYRIFWQMEYNMSAGGKNMYIELHTDNTCIDSFYEKPESVEQFKKRNSLLFHTFNTGGIKILYLKCKTEDSIKVLQLKNYGIEMFRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW27</accession>
    <name>A0AAD5XW27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001350">
        <property type="protein sequence ID" value="KAJ3204022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW27"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00531">
        <property type="entry name" value="NTF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13577">
        <property type="entry name" value="SnoaL_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="17259" checksum="82C20F70FE9FE1AD" modified="2024-05-29" version="1">MSKELAKVYNIYNLINSFFHYVDDFSLDVTTSEKFSDLFDENATFSFPKRNLEKKGREEIKQLCESMGTMFRGYSHLEYNIVVKVEEDSKTATSRSYWSAHNTFGELTAIGKHGDKFIFDETKGWLFAERVVELRWTKEEGSLVPLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWH9</accession>
    <name>A0AAD5XWH9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001893">
        <property type="protein sequence ID" value="KAJ3200491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041918219" description="DOMON domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="62" mass="7334" checksum="E95969E4781BEA0A" modified="2024-05-29" version="1" fragment="single">KMFNEKLITIWMMLATFSTSQTLCSENKEFCLFSRKFDDNVEFTFEVYQNLGWFGFGIGEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWK4</accession>
    <name>A0AAD5XWK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000201">
        <property type="protein sequence ID" value="KAJ3221928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="469" mass="51878" checksum="4842E8E6BD057C47" modified="2024-05-29" version="1">MSLSNLTVQPIEQVIALSPELITDENVFPVSQEVQENTKEEIDESMHKIASNPNVELESENIENSSKRNSINTPTQQDLIQRNLEKLSSKNSLEKLSSEKALEMAIGLKDMKDLSLSNQSIGSKMNLTKGLSSRSVEIVTVGDGDERKSVLEESEKSEDETKESFENSAVETKTQDSCTEFNNVQDHEDWLSDLDVEEITKRKNVLDQYLFSCKVLGIVPASYFLKRISSSNIVMKYHGLGPKGAQAIAEVLEYNSTIKHLDLTGNHCFSGGFNLGESLRTNQTLITLNLSKNNLKNYGGKEFSEMLMENNTLKTLILKENKLTDDEAVHLAQGLKHNNTLLVLDLSGNEIGDIGAGELGLGLSQNDGLKELNLSWNHIRPRGTTAFFTNIKENVTLTHLNFDSNGIADNGAQIANFLQRNAGVQILSLKLTDTGLTQIAKGIEAAEIKEGRLKLDELKNAKPDLNIME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX15</accession>
    <name>A0AAD5XX15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Follistatin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001371">
        <property type="protein sequence ID" value="KAJ3203845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX15"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003645">
        <property type="entry name" value="Fol_N"/>
    </dbReference>
    <dbReference type="SMART" id="SM00274">
        <property type="entry name" value="FOLN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Follistatin-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="1">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="1">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="1">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="1">
        <location>
            <begin position="186"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="219" mass="23785" checksum="91FB12D8F63DA5E9" modified="2024-05-29" version="1">MPTCDNVPCNKLSVCEVKPQTATECAKAVCVPFFKPDTKPVICPQVIPTCDNVPCNKLSVCEVKPQTATECAKAVCVPFFKREEPVMCPQVMPTCDNVPCNKLSVCEVKPQTATECAKAVCVPFFKREAKPVMCPQVMPTCDNVPCNKLSVCEVKPQTATECAKAVCVPFFKPDTKPVICPQVIPTCDNVPCNKLSVCEVKPQTATECAKAVCVPFFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX59</accession>
    <name>A0AAD5XX59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008017</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000839">
        <property type="protein sequence ID" value="KAJ3211359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX59"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07363">
        <property type="entry name" value="45_DOPA_Dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014436">
        <property type="entry name" value="Extradiol_dOase_DODA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004183">
        <property type="entry name" value="Xdiol_dOase_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30096:SF0">
        <property type="entry name" value="4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02900">
        <property type="entry name" value="LigB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53213">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="296"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="387"/>
            <end position="394"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3211359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="821" mass="93138" checksum="0DFB9406B091A72A" modified="2024-05-29" version="1">MYPNDPAHKETADFFKIEARKVLNLDNHNKPIAIVLITAHWENDVVTVSSSEKHKLLYDYYNFPKPAYDLKYNARGSPEIAEKIKNLLSTAGIKSRLDPNRGWDHGTFIPLKLIAPEEEIPIVQVSLVNTLDPRLHYKIGEALQSLRDENIAILGSGMTFHNNFGSKDGASSSVIFDEALTKVVLQGRSEREEGLANWEKLPAARECHQREEHLLPLHVVAGAGGSDEGYKVKSFKGLGVTLTKKVDPPVKNGINFNIQRKKLQLQNSINEHKKQLLSKHKEGSQNDSLKNESNNDIITAYRTRPLLRNELSQNKFEGIFMQDNLTYIYHPIDATLRDLALETHKFENVDFSFNEKHENEFVFQSLVKPLIPFVLNENGLATFIAYGQTGAGKTHTMSSFHEMIPDEIDFRKTLVKVCYFEIFGDDLFDLLNDRKPIFVLSTSTGTAIKGVTQEIVSSAEELKFFVESGTELRKTRATLKNDQSSRSHSVFILSLAAKTRENLKTFQLKKDSVFIEGNSLIIVDLAGSERNSDQTHHDKVRIKETQITNTSLMSLKDCIRNRYLISLLNANSNKHIHMPFRSSKLTQVLREGLDPNSTLKTKTVMIGHLAPSIEDSQHSLNTARYVSNLKASNNNNISTIDRVRSSSNGNSSESIKHPSKWTYKQLCLKIKNWSMNSIDLTKILKYHDTDVHSQNHEVGRPPVWLELSNMSTDSWVRHCKAQGVSSETAKMVFNKYKVELNVGRKQQKGEGENNMSSIFSHLKSFFSERISQQSTLESTKLNVYNVNCVKVGKEEMLQNDTRQKDSYMMVDDYLLNLLSCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXM2</accession>
    <name>A0AAD5XXM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005422</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000420">
        <property type="protein sequence ID" value="KAJ3217588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXM2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="16567" checksum="038C7DEE535E42C8" modified="2024-05-29" version="1">MNNNNHKRKYVDDAAEVEELNKSYFNNRIRTTQNSLEFSQHTQNNLFDVNFLFKKKLKLNNDAESISSETSSLGSPSYSIINSQLHTLHLLKMQRENKLVDSDPNFMKSELEDETFIEGVKNNLMQDVVFYPFNSILKELRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXT0</accession>
    <name>A0AAD5XXT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000992">
        <property type="protein sequence ID" value="KAJ3208484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXT0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3208484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="187" mass="21016" checksum="521E9D4E867483C1" modified="2024-05-29" version="1">MNYDTSLVKEKVYTRLVDTISVEDYPVPSLQETNEGSVKDLVGDILIPSLASHIKISNNNNIRLRREMKIISKDNESGGYEEYIVVDLINTTSERILIIVEAKQSSLGEGLKQCALAIKVSYDINNDNRPVYGFVVTSGSWRLLVYSGNSFKLSGPMEVLTEQLESNKENWLQSHSIVIDVIYSIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXU6</accession>
    <name>A0AAD5XXU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DEIH-box ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BRR2</name>
        <name evidence="9" type="ORF">HK099_008160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000087">
        <property type="protein sequence ID" value="KAJ3224615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18019">
        <property type="entry name" value="DEXHc_Brr2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18021">
        <property type="entry name" value="DEXHc_Brr2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000002">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000133">
        <property type="entry name" value="Pre-mRNA splicing helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000004">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000102">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000368">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein 200 kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000001">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000062">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000254">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000013">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041094">
        <property type="entry name" value="Brr2_helicase_PWI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048863">
        <property type="entry name" value="BRR2_plug"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21188">
        <property type="entry name" value="BRR2_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18149">
        <property type="entry name" value="Helicase_PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="508"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="726"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="1356"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="408"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2154" mass="243901" checksum="9F9D778D126469B7" modified="2024-05-29" version="1">MSSQVTQHDPRFSSRRNNESTGEAESLAGKIKKGQMGSRAVRTAIEEKEKKNKKKLEKEAKLKQSGAERKSNKQKGSSIFHKGYGFNNILQATDDFESLQYRPKTKETKEIYELILAFIQKVIGDSTQEVLRGVVDEVLSILKNENLKDFDKKKEIEVFTEPLGSEQFASLVNLGKKITDFKNEDVNDLDIDDGSKRILEDTIEDGVAVEFDEEEEYSEEDIIKEDEEEDVDTMGGIVVEGEDTEITSESMDVDVDEVVVSAAGDAVKDVSLNPHDIDAFWLQRTISRFYPDAQTAQTKTLLALNILSSSSQQVENKLVEEVTEFESDKFNLVKLLTRNREIIVWCTKLAKAGSVGEDVEKVKKEMQEKGLGHILEQLNVAPTRQVEGGGRSGRRGVVENAMELDEASNVQPSSNQPSDVSSFAPKSNIDLEELAFTQGGHLNTNKNCKLPQGSFIKSKKGYKEVHVPPPASNATKSKLIAISSLPEWAQTAFSGATSLNRVQSQVYPVAFNEDKNMLLCAPTGAGKTNCAMLTILRVIGQFTNQNTGLVDLDNFKIVYIAPMKALVAEMVQNFSKRLKDYGVTVAELSGDKQLTKAQIAETQVIVATPEKWDIITRKATDRSYTNLVRLIIIDEIHLLHDDRGPVLESIVTRTLRNVEQTQQPVRLVGLSATLPNSEDVAKFLRCPEGCLFVFDNSFRPCPLKQQYIGITEKKAIKRFQLMNDITYEKVMEEAGKNQMLIFVHSRKETAKSAKTIRDMALENESISQILRQESESYEILKLAATIVENPDLQNLLPYGFGIHHAGLTRSDKNTVEKLFAEGHIQVLCSTATLAWGVNLPAHTVIIRGTQVYSPEKGKWVELSPQDVLQMLGRAGRPQFDTHGEGIIITTHQELQYYLCLLNIQLPIESQFISKLSDNLNAEIVLGSIRNRDEAVQWLGYTYLYVRMRKNPALYGISVSERNEDPHLKQKRVDLIHAAALILDKCHMIKYDRKTGKFQGTELGRIASHYYISHKSMATYNMHLKPTMSQIDLFRVFALSDEFKFIPVRDEEKLELIKMVERVPIPIKEAIDEPTAKINVLLQSYISQLKLEGFALMADMVYVTQSAGRILRAIFEISLRRGWAQLTRKTLSLCQMVDKRMWLSMNPLRQFKNTPAHVIKKLEAREQSWESYKYLTPQVLGEYSGDRQLGNSIHRLIHQFPRLEVNARVSPITRSLLKVDLILKPDFVYDERVSGASEAFWVLVEDCDSELILHQDSFVLKKKYATEDHYLGFTVELFDPLPPNYFVSVISDRWLHCETRLPISFKHLILPEKYPPHTELLDMVQKTVSELKNKEFESVFKKHGITAFNPIQSQVFQALYLGDNNVFIGAPAGCGKTVCAELALMRLWSISPKARCVYIAPYDEVVNRKLAEWTDRFKDLLGGKNIVSLTGESTTDLKLLATGDVIFTTPQKWDVLSRRWKQRKDIQTIGLCIADEIHLIGDEIGPTYEIIVSRMIYMAKQTENKIRMVALGTSLANAKDVGHWIHAASSEIFNFHPSVRPVPLEIHIQGYNIPHFPSMMLAMNKPAYFALTQLADNKSSIVFVPSRKHCRLTAVELLTFCAADGDAKKFLKYPEGLTSLINFVQDKALSQMLEHGLAFYHEALSKSDRRIVEKLFTTGVIQVVIASKETCWSLPLKANLVVLMGAQYYEGKEHRYKDYQMTDVLQMMGLACKPIGGEAGKCVLMCQTVKKDFYKKFLYEALPVESHLDQSLHDHFNAEIVTKTIENMEEAVDYLTWTFYYRRLQLSDHLSELVENTLESLAKSKCISLDEHEVSPLNLGMIAAYYNINYVTMECFATSLGPKTKLRNILDIISHAAEFLDIPIRHHEDTILQKIYERLPYKVGEPKFNDPHLKTNILLQAHFSRVQLPSDLEADQKSILEKIVQLIQAAVDVISSNGWLAPALSAMELCQMTVQAMWDKDSPLRQIPHLGQTIIEVLKKKKVETVFELMEMEDDDRSEALSLSTKEMADVANFCNRYPNIEISYDLPENTVEQGGQVVVKVQLEREEEEEEENDKKLGSVIAPFYPKTKDEGWWIVIGDVKEKTLLAIKRTTLQKKAQLTLKFSPPEKIGKVDLIMYVMCDSYSGVDQEFNLDLTVLEGVSEGEEDSGDSEMNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXV4</accession>
    <name>A0AAD5XXV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar protein sorting/targeting protein PEP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VPS10_2</name>
        <name evidence="5" type="ORF">HK099_005003</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000373">
        <property type="protein sequence ID" value="KAJ3218576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031777">
        <property type="entry name" value="Sortilin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031778">
        <property type="entry name" value="Sortilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006581">
        <property type="entry name" value="VPS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050310">
        <property type="entry name" value="VPS10-sortilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106">
        <property type="entry name" value="SORTILIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106:SF27">
        <property type="entry name" value="SORTILIN-RELATED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15902">
        <property type="entry name" value="Sortilin-Vps10"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15901">
        <property type="entry name" value="Sortilin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00602">
        <property type="entry name" value="VPS10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VPS10" evidence="4">
        <location>
            <begin position="2"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="VPS10" evidence="4">
        <location>
            <begin position="519"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="475"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3218576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1429" mass="161177" checksum="D1BA62222366FD29" modified="2024-05-29" version="1">MSRDKRNLRLVRSNEYFKSDKTIVPLNGGVVGIGVKEKFLIAAVKSKEEMIMYVSKDGRNFNRAVFPLGSSLEQDGYTILESTKSSISVNVLVSNKASNFVPSYGTVFFSDSTGTQFNKGLEFVNRNSRGQVDFERVNALLFEGIIFANVVDNYNDFENGNLPDDYKKLVTTVSFNNGAKFVYLKPPEKNYAGNDWKCTVSNTPDKACSLHLHSITHPHKVFTTESAPGFVMGVGSVGSFLEPYEQCDTFISFDGGISWNHKYEVADFGSIIFLVRDTSDFIDEITYSTDRGENWKKFKAAIGDGKWRPRLTSLDADSTSQKILLFATSELNPRHHYVALFDFSKIQARTCEFDANHPDSSPDFEIWQPTNGDSECFLGRKLTYHRRKATATCSVNKKFKDMLPDESICPCTKADFECDINFKPTNEGNCEIVDKNALIQPVDCKLGETYMGTSGYRLIAGSSCKNGVSLADPVERECKPKTSPPGRGTTSPPNNKDPSVSLKEVPGLISFISYFKGSVVAIIRTNENSLYRTSDEGLTWSSITIPQDKGQLRQILFNSYTNTRVYLFFDNGKIFFSDNKLENPNNMKQLNTKDNILYNQFRYVNAMEFNSKNPEWLIFIGNTGKGCPYSRECYTSASFTKDHGNNWYHLDTFVQKCSFVISSNFKPEGLSDDAVYCLSFKYKNNISGQPERGSNANPLQLVLFTDNGRNKKVLIEEGAANFYAISNVLVVAQEKNDHLLVKTSIDGIQFVEGMFPLNVNVQKQGYTLLESLNSNGGLFIDSVQNDEKNQEYGTLFVSNKDATQFDFNLKNTNRNSKGFVDFERVQGLDGIILANIVSNPADLGIGNGVEKKVKTVFTLNNGMVWDSLKPPIKDSLGKNFCSFDENDCRLNVHINVDSYLRNNAIHSKENAAGIIIAVGNVGSHLAPYSLCDVFLSRDAGKSWVEIRKGPHRWAIGDHGGIISLVKDEKPTDTIYYSWDFGSSWGLYRFSSIPIKIFELNSEPTSTSVKFFISGVYESSSIKSVLVGVDFSNIFSRECSKDNRDFEKWNVGKNSCFLGNEVSYWRRKNDAVCTVHKEFQELDKETKVCECTKDDFECDKNFWRNTEGKCVLMGRDPSQPHDCQTTYKSSNGYRRIALSKCVGGENLEMQIDRKCNDFKSPTGEVYQNGRFFEHTVSDFSYFQDSNVVVFRDSFGVVFYSDNNGLDWKLVPVNSGDLISSIVLDPYRGNRMFFIVADADRLYYTNDKLKTLSRLALPLHYNPNFPLALATHPIEEKYLLWTGGKDCGKNSYSCHSETHFTTDLQTFTLVDTYSENCAFMRTDKFLIPHKDSIVCSSFETKSGFQREQNINNNNLILKYTINFGKVWNTIKNSLLNFAIVEEYMIVAVLEKGASDVGLFISRNGIEFEMATFPENYKLSKIGCKYKGIKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZB0</accession>
    <name>A0AAD5XZB0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdopterin synthase catalytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000497">
        <property type="protein sequence ID" value="KAJ3216128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZB0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="entry name" value="Molybdopterin biosynthesis MoaE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23404">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="Molybdopterin synthase subunit MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17639" checksum="B647EDA35104B9FA" modified="2024-05-29" version="1" fragment="single">MLDEVELMKYHNDFVDITDENLNLSVLIDKVRTEDSGAICTFSGTTRNYFVVDGIKRKVVSLEYESYTPMAIKEMQKTVKLARTKFQDINKIAVQHKIGKCLVGEESVCIAVSSSHRKVSFLACEFIIDELKRTCPIWKKEIYEDGSFNWKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZG0</accession>
    <name>A0AAD5XZG0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005702</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000458">
        <property type="protein sequence ID" value="KAJ3216833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZG0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="190"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="51423" checksum="6496EF560ABB2979" modified="2024-05-29" version="1">MTEDNELLLSLMNMGFDYFLCKKAISNGSKTLEEASNWQAKIFTHLLTVKFRILNQIAPANVNYEEPSSPKLSLKKLPSDLVASTSSSSDQFSISQQNTEKRISTSVEDASLKVKSRYKESRKDFQDIYIEKELEKVKKLKNSEFERKKEILRQIKDDRNKLKKVSGDRIIGRIEEKNPEKNSVKATISPSNDDTTMQFRLPTGSLIRKKFLVSSTLEYVFNFVETNLSSEEVLRGFELLVSFPRKVFTRDHEGATTISDAGLRNATLSILLKTPVPEIIAGGEEIQNEVVIEDENSEHDMDEDSNDNSDDDLNIFGDPWANLGDGHGLGTQSSSEMNLEPTTAGELEFASSNFDALQQRRERMAAARTRFINQHDDLEDQTALKIPVEKKHQILSLKDLSLKIASRTVLECANDHDKKLSVLKNFSNDLGLTLIQYLIKNKKFDRACVEKLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZI4</accession>
    <name>A0AAD5XZI4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">L domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000441">
        <property type="protein sequence ID" value="KAJ3217144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZI4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000383">
        <property type="entry name" value="Leucine-rich repeat receptor protein kinase EMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051848">
        <property type="entry name" value="PGIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059">
        <property type="entry name" value="POLYGALACTURONASE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059:SF4">
        <property type="entry name" value="POLYGALACTURONASE INHIBITOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042239314" description="L domain-like protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="36651" checksum="06E36294E63EE264" modified="2024-05-29" version="1">MKLSAILIVAAAILNSSNAIKPITVDPAMYQQSPDCLTIWAWLPQIYPRGVTNCCEIQANLKESMPILLTCDANLRVTKINIGQTYNPASTLVRQNWKSTGAGVLNAPLPPYLGNLTELKTFIVGEAFMFGPLPKELSKLTKLEHFSVGNNGLSGEIPEGLFSDMVNLVSIDLSKNKFTGPVPDSFVNLPNLISVKLGQNKFSGPLPDFSPMTSVGKGPKYNVEDGGFDPVCDLNGLGSQVCIAKEGDLTKVPEVCVLPTPSPTVCVEKVVKSSPTPIYAEVVKPEAAGLSSAAKVAIGVSVGLVLVIAIYYVSFTFIRKGNEKDAADFEKRKVEKVDMSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZK2</accession>
    <name>A0AAD5XZK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZK2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="328" mass="37581" checksum="C27D5995B80F95FC" modified="2024-05-29" version="1">MLELQLLLPNEEVLPINCTSKPHSDTTSLFQLFVNLKIDSIPVNPKKTSLQSEMLKSEPLLEDNINLVASEIEKAEFNRNFNSAIKKIYKGNTNINFDWFEESTILSNEINATSQSLANDNNCDLTKFEKIFTAKFNIFIEFFLNLKNFKENFLGEYFLKENSKSKNVLVDSKFDLLDDDTNEPDVCKFSVLHLSLKFYEIQNNKVVDLFTLIDLNLGSTAKFSILPHYLTFNFIRVNNSETEIEFPLQVDFGSRSKNLSATLYILHGFITFNGLDFITYTRLREKGVTFSRCLNGEVTSVNLFGSIKSKGVRVVIYCLQEPEKSLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZK5</accession>
    <name>A0AAD5XZK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PKA1_3</name>
        <name evidence="13" type="ORF">HK099_005474</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000428">
        <property type="protein sequence ID" value="KAJ3217433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZK5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="234"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="499"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="58"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="65"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3217433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="553" mass="61222" checksum="D4FE0E45A3104B21" modified="2024-05-29" version="1">MEGQLPTTPTQAVLSKKPSLGSQVLNNENSKVKLDMSQISTASNSQSRLILPEIVPTKPQLTATSSPKSSRPSSAITNLNRNKENSLSNSNSKLNYNSNSFNSKDREKSNLSKGGASRDGNGSGKVESLRSSIKPINGIKLAALDDKVNKIVEKVDSLSSLQNDSKNLIKQSDTINSSNNKNVIETKPLFAKDVVAPLSDIKNLKISDEKTSLSSTTQSKKSTATEQKYTLSDFTVMRTLGTGSFGRVHLVKLNSTGTFYAMKALKKSEIVKLRQVEHTMNEKSILTQVSMPFTVNLLCTFQDSIHLFLVLEYVSGGELFSYLRKAGRFPAEVAKFYAAEVILAFEHLHARDIIYRDLKPENLLVDCKGNIKITDFERSIKLSTQIGFAKHVPDQTWTLCGTPDYLAPEIIQSKGYGKAVDWWAVGVLIYEMIAGHPPFFDDDHFKLYEKIVTCKLKFPSFFDPVAKDLVKKLLTPDLSKRFGNLKSGVEDIKQHKWFTGVNWGVLLKLGIPAPFIPKLSHPGDASNFDSYPEDHDPYGLPGLDPFGDKFAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZQ2</accession>
    <name>A0AAD5XZQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-binding cassette sub- A member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ABCA1_2</name>
        <name evidence="8" type="ORF">HK099_005209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000398">
        <property type="protein sequence ID" value="KAJ3218065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZQ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF205">
        <property type="entry name" value="ABC TRANSPORTER A FAMILY MEMBER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="485"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="7">
        <location>
            <begin position="191"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="599"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3218065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="717" mass="81649" checksum="0BF8043979E1D2C0" modified="2024-05-29" version="1">MSDELIDDNNIGKFRSQAIRSNFIIEFFSQLKVMLKRNFILQLRYRNSTLAQTILAPLIFQLLLFVLQQADYERQRESNPHPTPYSLTGIPTCQGTSYQDNNCINIFYTPAEEPYTSFMKTFAELNSKRMNQPPFPIEDPIDDTNFTPTKNLGIVGVPNADFIYDYVFQNPNTTRWGITFNQTKNETGPTPNLNIQYQIWYNVSLTANSSDIFGNELLGFVRGLDEAIITNLNDPNAKVTADIDVSLKDWPIIPPSTVSDLVVQQLGPVFFFCSEMVIFISVINQIVSEKELKLRIALEMMGLKPSVFWLSNFISNSVLVLCNALVTVLLGIAFNFTAFKNTSFFVNLLLFFLFGEAMVCFAYFITCFVQKAKIGILIGIFMFIIGLLFESFVFSSPFVGYIWWDPKSVDPIAWKTLIFIPFFNFGKMFLDIGSFTSGYRDALSDTFIPGPGFSVETLYDTLPSNLLPNYGDNNQPQVPRPVDSIFYLLMNIAFYYTLTLYFDQIVPNEFGNYRNLLFFLTPSYWGFSNKKELKNVEWLKKVKANSGGIVLDNEEEDVVEERKVALSNEHWPAIKIVNLRKVFRKSRFYKSKIDKIAVKDSCLTFEEGKLLALLGQNGAGKSTTMNILSGLTPATKGDALIYGYSVRYQMSKINEIMGSCPQHDILFEDLTAKEHIELYAGLKGVPKKDWPMLIEDRLKCVRLWQVRNARAGTYSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZY1</accession>
    <name>A0AAD5XZY1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I and III subunit RPAC2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPC19</name>
        <name evidence="8" type="ORF">HK099_003934</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000267">
        <property type="protein sequence ID" value="KAJ3220870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZY1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07029">
        <property type="entry name" value="RNAP_I_III_AC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerases I and III subunit RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033898">
        <property type="entry name" value="RNAP_AC19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF28">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="7">
        <location>
            <begin position="30"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="125" mass="14272" checksum="63E8529FF118E90A" modified="2024-05-29" version="1">MSAMLEPGQIITTFGPKVQLLEQNENDDSCATFQIKDEDHTLGNSLRYMLMKNPNVTLAGYSLPHPSEARFNLRIQTDGTIKPLDALNKGLDDLIDMFQEIYDKFDYKLKLKDYILEEDAEPDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-11-27" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y098</accession>
    <name>A0AAD5Y098_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MED14_1</name>
        <name evidence="11" type="ORF">HK099_004442</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000312">
        <property type="protein sequence ID" value="KAJ3220213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055122">
        <property type="entry name" value="Med14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013947">
        <property type="entry name" value="Mediator_Med14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809">
        <property type="entry name" value="MEDIATOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08638">
        <property type="entry name" value="Med14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit MED14 N-terminal" evidence="10">
        <location>
            <begin position="289"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3220213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1455" mass="166951" checksum="F4CC7CD7B66328DB" modified="2024-05-29" version="1">MVRKLRPVRIQDELLHERDLRFVHDILFPEVKNNLKEFLMKNWKDEELNQKINDLKNLNVKDLAENTHGCVKILDEEENSVSNEKIIQSIVDNVLWMMSIDSSGSVEAQKLLLGYSEKGDLTQFISGYFDTNIGLKTEKSSYEAIAKNIKEDPSKILFLSDNLKEIAAAKLADFQALVVFRPGNPDLEIIDKEDGKCVKYQIDESSESMELELVEDCTAVFKLNSFLSKPKKTKIFRKENAIVNPIVSNMVDIKMETEDKKIDFSILKEIKSSEIFTLDNSIEHFDDQFIPITYLIDILSNKSYQQLLNLCEVLQNLQHLDRKKQLLDYSIKERSQFSKLLVLIKWAKKASHDINRCQRFHALIDKTDFCFSKSSDILFEISRALKANRDPLYDISTAIDVLTTGKYQRLPLVIKRRLIPPRLLSKSEIDFTYKKIEDIIRRRLFCDEVIPIQLRRGIKIGNGCVTFTVENEFKVSLTLVSLDSNIPWIISDLKILVHLEKDIYENIPFGLQESQINYIIDIAQQKIDAKTCSSLTKPGTAENLFCLNFQLEILHTQTIHLMRTRWAGHLEVSIDRSTSLLRVRYWVLNDKKTLPSNQKFKNYLEIGISEKNNDIELLNSEAEETKESAIIRSFSGAFGIDRWLSLKGFSLHYNKKNVVESKVLVMEEKDCKIDSSHLDTELLLYRITKIKAKEIIHHLHEILISCYISTKANSKLFLSKSTLLESSSELVFAGFTEHDIKITDVKNLFFASEEESPQPDQCLLIRYLPDRYLRCSVELRTGKLILTELDKPFEFEKQHFRFVEEKLNSDINSAAEAFLKLRTKTVLEKLEAMSVYLDFEPLNQIPVKDIRLITNPNCLDIIEDRGLSESTLFLRYKDFPKFYIVISVYGTRKDQYIKDHEELDEVELKDGCLYKIWLCQIVLSENLTNVEVVKSIVISTEEVGIEKDVGVGDYWTVIKLEYLSKIKEFGRRNKWMQNHGIRIKTFDITTLTLGLQNNKNTEDEIIICWKSCIKDLASVPKVAGKFEATFNFGDLTQTSENSNFQLMLVTVTNQIINTQKDLVLALDVILRLYRFENLYQLSREFIKSVDIKTISPLHHRLTIYNYGLDFIILQNGLISLVDATSSSFDGEQFSTEKEDLNFDTCPYLRNPDNSSSLINALSQVINGSAIASKVFVFPIQAGFIFNPNFIQYVLDCVKNLILIIEDLKWFQQLSQMYLLKNRLSVFNPPDSKTLSAQFTTSNLSCSVSISLTKKVVVNITPNSAILNNCDLTVADFSLISSCLTSKINLPSAVTTRDKLKFILDFNLLPPSVLRDFAQLFVTEQNADMEICIISPPHSQGHLPAQGTLGLILDIDNNRICTTVKFKGSDVKGFKYNYTTAVIGLWKNDNDAELISTLNLDENTLNEQRNRILPLEMQSTIDGKLFLISTKYKNSQPGYGTLFRTISALAGRRRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0F7</accession>
    <name>A0AAD5Y0F7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dynein regulatory complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LRRC48</name>
        <name evidence="3" type="ORF">HK099_003108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000209">
        <property type="protein sequence ID" value="KAJ3221775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0F7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="417" mass="49013" checksum="58C00F14A6C34644" modified="2024-05-29" version="1" fragment="single">ILKIDNLWGFENITKLQLDNNIIERIENIQFLVNLTWLDLSFNNISVIEGLEGLTKLTDITLYNNRISKIENLDDLVNLNVLSIGNNNLTLLEDVEEAKGKYMDDLIALEEEEKVANSRKEEDMKLQEMELLYQSAHIEGIDKLFNSMFQDDPDFQKLVAIDKVIINDLKDELKPKIDLILEDLSKFCLKRHEEIQEEKSIFDNCKFQNQNYHDLECIKILNEYQHSKKQLFRTIHLNKEVDVDEIIKNLKDNTQELSDILMSHEMQLVEQFEDIIKEFERTYIELSAGITEIGQTSMSRIRELENEFHEKFSETVMLLFDRYNKGDVEEEVEDSIRDLLSDKDALLNTVNQSHDFRLSKFDHQEDILVTGVAKVNELVLNKTHDTEVQRNRNRLCEIITFLEKCNAEIEQLEESSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y116</accession>
    <name>A0AAD5Y116_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y116"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21203">
        <property type="entry name" value="ECM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042039300" description="ER membrane protein complex subunit 10" evidence="1">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="21695" checksum="C33725D1EE33F0D2" modified="2024-05-29" version="1">MFVKISFIIAILLINLIKSNEIHVYSSLLSNDEVALHTRALIEIKNNEEISYKNLLEVNKKTKKPVEHDQTQFYYVTFKQHNRVFHYAVQICQIVQSNYRENITVHLNSKEKAFNESNFSTPTLKLVKQFKVSRPRSEPLPELKEDGSTPEPEKTFLQKYWYYLIPLAIILVTSGGDDKPGVAAPVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y256</accession>
    <name>A0AAD5Y256_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007588</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000075">
        <property type="protein sequence ID" value="KAJ3224959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031549">
        <property type="entry name" value="ASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056310">
        <property type="entry name" value="Ig-CFAP74_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22538">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22538:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15780">
        <property type="entry name" value="ASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24798">
        <property type="entry name" value="Ig-CFAP74_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24771">
        <property type="entry name" value="Ig_CFAP74_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFAP74 fourth Ig-like" evidence="5">
        <location>
            <begin position="997"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="domain" description="Abnormal spindle-like microcephaly-associated protein ASH" evidence="4">
        <location>
            <begin position="1434"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1343"/>
            <end position="1372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1909" mass="217351" checksum="0F481CD7D9C0B411" modified="2024-05-29" version="1">MSDNGREDVILLRQAKSLGNVLQAVNSDCKILIDKKISISQQNLLPDTMEFSKKHTDFLNELNLQIDCIKKNRILQSEEDTNYSDSELFPGYSFSTKGNKLFDFPITIETTPHDVLKQMSDEELSTFREITMQKYNEPTFKHNLIESRERLLNKKFFNSFHQEVKKISYELGEAELNIKEYKNIFQSSINELKVTIPKIKNYLSDNIPPYAVSMKNMYNTFSLNSILTLRPDDLLSIPEEILNFKLPIDDFLMMDRNYRLLYDEFMFYQDQLLNALCVIEELEIKIIPLHQQLCKLEFEEERIQSIEQELLELDILDKTEKLVYHQEKEREKNKQLKCREKLTKKETEMELMSKDETFKNEMKKMEEMKRNRRKFIHRFKRILDMVCKQELKSTEATAMIHKLNKKKKDLEILVSECKIIRQHLKKTSISEKKENKIYMKEREIMDKKKTDILGKIIKEEAKRKLAEQENEMINRINKSLENRNPNPENAFAYEEIIPRKEKKTIKKSLPCEKASKKLEAETINVTENTMLGVENSLETVVVQKVPEKKHLPPPQHKFVKPAETSKSSITSIPFTADPSIVLFKDYDPEKVYKRVFTLTNTSSCVNAFRLHPISEDFQDYFVISYKPIGRMSAGMMAELEVTFNAPSGFNENLEIEVTGFAEIGGDFSFKIGCQKKIAFPFLKSISEKNGMMQKFHRQDNGKNDNDASITKDVLSAGLLKKKNFIAEKISDDKFLIDFGSCLGGEKRTVRMVNYGALKTDFEIEVSQEHLAISNDNLTNPLETFFEVEGKSGSLHSFGNAIIEITFRNLQCLGVVRERITIKFSSSELQPIVLDCIAEMVNYPITIEKNLVDFGTCVYQNSYRDDGSIVLKNDGNVSLKYSISSSFKNFASKADAEKNANSMKLGRPSKSSLVLNIPGIGDFEVIPKQGFIQSKSTSALRFKFTPYKLSGKDVADGPKLFCVPLELKYVSSNHNCILNLTLKGIVTSDAISFYSENFNQNVLNFGNCSVDEVSINELKIFNHSHLPQSLLFETKETSLNLKEDGFVTSDGDQKKIFLDPRTETIVNVAFCPLDIGEQTLKFTLKKQKQNFNFSCVGVGITPLLQFEKNEIQFSETGLGSLSSAKVYICKPFVKDNRPDHLPWKRKVTAKEIVSETAGASHLSKLEEEVSFEFLKPKIVDLSCGGRNEEELYFHYTANDECPLRIFPAKGSLVTGEKIAVDITLSPTIKLQGVVSAITQRQELILEKKKADQEQKEELARREQEKRDLEAAAMLSAKRDKKGGKNSVAHVLAKLPDPAEVEVKKIEEVEFNPPMNYFDNYVDTTLTIIVPCLTKKRDNKFTRKNNFLKQVNSKFEAENQNESEEMKNENLSLDTQMIFLKILAPIVRPNFIVEAWSDFLPLKATSATENLSNSLPKNEDEVPNPIEDCLFQLTSGKLDFDRVPIGKSLVQTIKIRNTTDKEIQITSTLLNPQGPFYLAKALRSIKPNQFFVVKVSFEPTKIGANLSMMQLKSDGSQITIKLNGEGVIPSIIVEPVEKRLTFSDIVVGESSTSTFKIHNPCHFPIKYSFSFKEKDNSICDSEDFEPCFKVFPTECVLAPGIRQEVSVTFDPKNESDLFHTILDINFWGKSEDHTIDIFGRAWETSTALLGYDNLPLSMDPQYIVDGQNDLELPSSQDIAALISKSKTSIGNEHKSKLSLDKSVDSAELLNSNGKDRVKAIDTRFVTLKCSWKKLNKDSDTINQPWTVDFKELQVANLKTTQKLENTGKGTKAIAAQYTIERIKSTFEYVEETGHFVVKAEDNATTAGYLFEIEPTAGTIEFGTSKTLNIRLIEAILEQSKLDANQEKDKEKKKKNIDKSSASAIASVPVSTPIKVETYFRVRLKGGYHAVEPKGPTNANDKRDWILKVVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3J0</accession>
    <name>A0AAD5Y3J0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Synaptobrevin homolog YKT6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_000445</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3J0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15843">
        <property type="entry name" value="R-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.50:FF:000015">
        <property type="entry name" value="Synaptobrevin 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000004">
        <property type="entry name" value="Vesicle-associated membrane protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051097">
        <property type="entry name" value="Synaptobrevin-like_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136">
        <property type="entry name" value="SNARE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136:SF168">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00417">
        <property type="entry name" value="SYNAPTOBREVIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="11">
        <location>
            <begin position="66"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="183"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3227772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="32109" checksum="0AB6EAA68E83FF7E" modified="2024-05-29" version="1">MCSFRKLKDHILKTNLTRLLEKKNICLEKLKVEEENEKLLEKFNKISKSTEHLDSKLQNELKEKLKVARGPVILTEFATNTGNFTTITQHILEKIPEGDSKLTYVYDRHLFHYIQKNGIIYMCMVDDNFGRRIAFAFLEDIKRRFETSYGDRAQDAIAYGLNEFSKTLSTQMEFFSSNAGADRIRQVQGEIEQVKDVMVQNIEKVLERGERIDILVDKTDTLNQASFAFKKRSTALRRQMWWKNQKIICLSFLAAILVIHLLISAACGFPLWSKCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSG0</accession>
    <name>A0AAD5TSG0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002101">
        <property type="protein sequence ID" value="KAJ3199496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSG0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="67" mass="7950" checksum="23760898085E3DD8" modified="2024-05-29" version="1" fragment="single">ENELEMFYGEYCGNLCKTFWEYQKILAENSKFREYLLDIEKNNTDVSLFDLLCLPIKRLSEIGTICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSL1</accession>
    <name>A0AAD5TSL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003062</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002064">
        <property type="protein sequence ID" value="KAJ3199667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSL1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="8">
        <location>
            <begin position="19"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3199667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="197" mass="22845" checksum="5500E995C52B3C0B" modified="2024-05-29" version="1" fragment="single">YKPLKPRNHPRYKPYRDVTILVPTIDTGDEIKLALKSWLLSKPFEIIFITIPSKKKDLESLALSLDSQSSVIKVITVKKANKRNQMIAGINEVKTPIIVFADDDVIWPPTMLEWITAPFEDRKCGGVDCEEEEEEGNSFKDKNIYENFDLKTGSEDQLRVEEMGDKANFREKLNFKMDDEEFEYVDYQLVIDDDDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT11</accession>
    <name>A0AAD5TT11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002074">
        <property type="protein sequence ID" value="KAJ3199619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT11"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="24859" checksum="40962AC0AFEA4D1B" modified="2024-05-29" version="1" fragment="single">MQGHSQTKVSGNKLLIYGGLLSSGEVSNTLYEYNYDNTTLSAIKPIGDVFPSKLMSHSAVYRKKTNELFVFAGTPDKSAYNDVMYSYDITANKWSIVPVKGALPAGRSLQAVDIIDDEIFMFGGSSQGSILNDFWVFSFITNTWSQRVNSVSPLAYFGSSLTAVSQNNTLILFGGTNTGSQSNQLWSYSTVEKVWTSIKPSGTPPPGFSQGSGVVLDNRRILYVGGLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT32</accession>
    <name>A0AAD5TT32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pachytene checkpoint protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TRIP13</name>
        <name evidence="7" type="ORF">HK099_002378</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. PCH2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001786">
        <property type="protein sequence ID" value="KAJ3201079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT32"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044539">
        <property type="entry name" value="Pch2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058249">
        <property type="entry name" value="Pch2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991:SF1">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23242">
        <property type="entry name" value="AAA_lid_TRIP13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0469">Meiosis</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="129"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3201079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="372" mass="42190" checksum="057BB69A305466CC" modified="2024-05-29" version="1">MEISCSIEILLKGDSEVDHTTLKAEFLKHLKTLTKTLQQNSTIPLANFKNNHLLFDNIETAKVCEIIYKDQSFFYITDLKIECFVYKLNDLNDEDQDEDEEMDGVDDGGIVQFRQESLPSSKFEGLWESLIFVLLHGPPGTGKTSLCKALAQKLSIRLAEHFPYGKFIEINSHSLFSKYFSESGKLVGKLFSDINQFLDDESTFICLLIDEVESLTSARKQCLNGMEPSDSIRVVNALLTQLDQLKNRKNVCVFTTSNLTNAIDDAFIDRADVMQFIGNPSKKAIYIILSSCLNELIRCGLIFSNKQKAILDYKIVENLKNNIEKNNVNSFCVNESSISLFEISTELETRNFSGRSIRKLPFLTHAYSFNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTJ1</accession>
    <name>A0AAD5TTJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">E1 ubiquitin-activating protein uba2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UBA2_2</name>
        <name evidence="7" type="ORF">HK099_001595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Protein modification.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001466">
        <property type="protein sequence ID" value="KAJ3203166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTJ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF5">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="6">
        <location>
            <begin position="15"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00043952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3203166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="192" mass="21724" checksum="FCC4384DC8CBD26A" modified="2024-05-29" version="1" fragment="single">MTQTSKKKNRNDHNIEILGQNTFNKVQNSKVLMVGTGGIGCELIKNLVLSGFKDIIMVDFDTIDLSNLNRQFLFQKKHIKKSKAHVAKEAALLFNDQVKIQSFNDSIFDEKFNLNWFKNFDIIFNALDNLPARRHVNLMAMAANVPLVESGTAGYLGQVTVHKKNLYECFDCEPKPTPKTFPVCTIRSTPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU60</accession>
    <name>A0AAD5TU60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">2-oxoglutarate dehydrogenase complex E2 component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">KGD2_1</name>
        <name evidence="9" type="ORF">HK099_001334</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the alpha-ketoglutarate dehydrogenase component 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001365">
        <property type="protein sequence ID" value="KAJ3203895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU60"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020373">
        <property type="entry name" value="Kgd4/YMR-31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10937">
        <property type="entry name" value="Kgd4-YMR31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="50"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3203895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="198" mass="22122" checksum="0B635E7BEB57BEC7" modified="2024-05-29" version="1" fragment="single">VGDYVARDEHIATVETDKVDVTVNSPNSGVILELFSKEGDTIVVGGDLFKIDTDGSPNQKSSSNEKPKPVESKAAQPKQSPSKGESLRFAENKLDEKDHHYKRTPLIKFLGPRKNLEHHETKTNIQEEKVSATDKSTSSQPPKLEKRDGKQIVYYDDPIELPSHYKRSYLSQVEIDAIEAGADFSSNLGAYSLNFFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUB1</accession>
    <name>A0AAD5TUB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001312">
        <property type="protein sequence ID" value="KAJ3204333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUB1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042133132" evidence="2">
        <location>
            <begin position="18"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="234" mass="27560" checksum="4749C5C82F35A449" modified="2024-05-29" version="1" fragment="single">MKLSNLVLLAIASLATAAPSYGYEKHVDKYDRYNNYGKDVYHHKNNYYKKHNNYHKKNYGHHVKKHYGGYHKNHGYDKYVKKNKYYGKSYVDAAELDDQEIDDDDSTLFDDDDNFDIQAVNGEELDDQDAFDDEDNEDNEDDDDDDDSNVQELNGQEFESQTAYYASPPKENKKDYGKSEKEDYGKTEKKGDYGKSEKEDKDYGKKDKYVKKYGYKSYKKKHYGKSDDEKDYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUK0</accession>
    <name>A0AAD5TUK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002062">
        <property type="protein sequence ID" value="KAJ3199673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUK0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="248" mass="28869" checksum="3C3B8D0854924BF6" modified="2024-05-29" version="1" fragment="single">VGGEDNVPQLEIDELFNILNLPKQLFLKKEEVDTENKLNYQSEYTLNLTEDTTILSSTILPIPKVELETQNTESKNYFIKVDSKILFEEEEDKNLLILKSINDYAHYSTYHFISMAMHFSPLKTVRIHFNSQLLKNLPWKACLQNKLTKVDFRTRVNDNFFETILYDNVKNVNLVSTKLTSLYVLWGEVSDVTLSLISKSFPNLRSLEIIICNSYFGRVRRYNSPTENTLITDNGINKTILLSFFFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUR7</accession>
    <name>A0AAD5TUR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000664</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CKS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001165">
        <property type="protein sequence ID" value="KAJ3205932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUR7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00296">
        <property type="entry name" value="CYCLINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="159"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="191"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3205932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="249" mass="29503" checksum="235909447ADA9BD9" modified="2024-05-29" version="1" fragment="single">MSTTGQKSKLKRKSRASLAIFDDASEHIIQDPINFELKMTKQKFEENLILELELLRDTYKIEELIDRIYYSRRYKDEDNVEHRHVILPKELYNIIPDQYKNRILSEMEWRGLGIRQSPGWIHYCTHNPEPYIFLFKRTETEKETFDFIEEKTLSSPMINKRRRSFKNDSRETETSSNVLTETQISPNSPKHSKENDENIEIPERPSKDNSGKKSITKEKVMLKNDVEKLRKKSKLSVPPEGLNININML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUT1</accession>
    <name>A0AAD5TUT1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GET4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001070">
        <property type="protein sequence ID" value="KAJ3207235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUT1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045048">
        <property type="term" value="P:protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007317">
        <property type="entry name" value="GET4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875:SF0">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04190">
        <property type="entry name" value="GET4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="355" mass="41114" checksum="5F6F9A60996DB1A7" modified="2024-05-29" version="1">MSKQGTEKVLTKLKAAVDQKNFYEAHQMYHSLCQRYVKQANYKAAVDLLHSGILTLLNAGNRKKQKNKNLPFPIDQNGSAFDLSQRLLEIFDQQKFPVTEENKEILIEIFEFFSNDSNSKKDFAKLCIKWSSKYGKNKNGDPQLNHIFGNAFYSEGEFYLAEEFFVNGTDQSAKSFGKMLYFWSKQVEEVDLGYFVARGVLQYLALFKTNQAHQLYEIFIKEIQNNENLEELTLTSLSFDSKVNINEKSLTLFKSPLLNFTKFLLLCVERGEICMPSFIKINNEYKQNLTLYNEDAMKEEEKEDRFLNQLMSCVGENYFGLKVSKPVNPLQNMFNSLFSSPNSEAIESNESMEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVK6</accession>
    <name>A0AAD5TVK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002077">
        <property type="protein sequence ID" value="KAJ3199607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVK6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="30174" checksum="C9A77FA0F579DB79" modified="2024-05-29" version="1" fragment="single">NEIKDDEAPLFGEDELKSKNNDEGTDNEKIVEKLFLPKDVDKSYQANIELQDTEEDYFSDFSDVNSDSCYFVEEEDDEQQDSAKTANFSFVNQDYKNKLIKIKQSNEKKKELKVDDCELFPPNFTESSIPKCELKTNSENKKNKKLNFSGVDDFITKNATKNLKDTDALDENELEEKEIQQAIFLSLKTLEMENKKFQDTNNLTVRELSLNQLSDYGEDEDYQIALAIEQSLKEEQNFSLQRESTLVEFECRGKGKERAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVN7</accession>
    <name>A0AAD5TVN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000865">
        <property type="protein sequence ID" value="KAJ3210939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVN7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="372" mass="43520" checksum="30C8F8FC227C38EF" modified="2024-05-29" version="1">MSVDFLDSNELNFENFTNSNSTNDTYSDFFPDIEVVKPQLISDRLSFMMSLVFEVLCILFTLGYVLYALNLLRVNRKFKNTVSFFITYLTYTLKTVFQYLSFAYGVVYDEHSIAILELISNVFWVIAHYTFVLMIQKRFQILHLIKPYNKKWDYFLTFLSTLILGIFLLINILFTEFSGLLISGEEGHFFTVLYYSSVAIVEFYVGFMDILLSGYLFYHFLAIPTIQDTFKQNSHYYGLKALKELMVKIKVFWSSLVVIVFLKSFILAITNMDYFYVQYNLYYVIADFAYFLSILQIAFTFEYFNQLEFLTKMASKSVKQQILAERKDEFLECPSSNISSLLVDSIQPSEVDWLKHNKTTTCTGSKSEVEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVV6</accession>
    <name>A0AAD5TVV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000822">
        <property type="protein sequence ID" value="KAJ3211643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVV6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="204" mass="22926" checksum="781EF79320DF2B79" modified="2024-05-29" version="1">MKYNSSSPCYSCDQNFLCIQNLFTKSYLEKDSLNASYHSCVCGSEKRVNDTLHCLNLALNKTCDFENHPFIFLYTLLLIDEPSLAANKPNNISRNPNNSAILPLLQKNCVNGLNENALNFIVNYNAENANVTYTNKNNFVSKENYSSSIIIGVLLLLLILTGVFAILFIKFKKKKKKDDKKSAADDSEVTSSSTRTLPYINIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVX4</accession>
    <name>A0AAD5TVX4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TAFII28-like protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002554</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001855">
        <property type="protein sequence ID" value="KAJ3200679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVX4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045127">
        <property type="entry name" value="TAF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006809">
        <property type="entry name" value="TAFII28_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13218">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04719">
        <property type="entry name" value="TAFII28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII28-like protein" evidence="7">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3200679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="144" mass="17249" checksum="9552B6002864DA35" modified="2024-05-29" version="1">MFFPSSSSNYRPPQPPPEPTQQQRQAALQQQQQQQHTLQLPQRQTDLDEEEEDDWDEEEENEEKQPDNTEALKILLSSMDEEQSQRYEAYRRTKFSKAPIKKVKKEEWGHEGAISPAHLREAYRRYQRDKHVTLIPNNSRKRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWF9</accession>
    <name>A0AAD5TWF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000787">
        <property type="protein sequence ID" value="KAJ3212279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWF9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="533" mass="63129" checksum="F8AF5A562C38A618" modified="2024-05-29" version="1">MLFSPFNSPTNKPINLREERTSLNILSRINFELESITLYDNISIEKFSSKLQEFKWQLYEHTDLPVDVRLRLQKLVLKHKTSLSLNMKLDKLDLLNKDFFYDLNLSKPYSNVLIKTLTYKNKDSKLILDDIFLPSVSKMQQKSRILNQVEAFDVWNIKSFLDSMTWDLHQLKFNLSKIFQHLNDQQFEQIKQSISSPLKNLGPEKQTVKKFFLPTIKRAKVLNLQDLESLLLLIFIINQFNIKFALEANDVPFTEGNFLLTLASNNGFEIPPIFFEFWKNCVFSHGNQKFVKSAVFLENAKYNDRLMENGINFIRGDQTETAKFLKINHIYFGLLGLLYFKLSELDECEDKIDRIKQGFFYLNTFFETRKLIEAADKREKEELNDKLLEEWYHKYFKNKFEEVFKIMREKCHDDKISMKHIAEKRDVKKNEEEIFKKSVFYKKMFSLEEEEEYKPPSVGLYETINFEGLEELDSIKYEPEETVAQAGISNFSNTPAAKRINKRFEELDKLNCSSNVIENDEDESLLKYIMDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX87</accession>
    <name>A0AAD5TX87_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000720">
        <property type="protein sequence ID" value="KAJ3213354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX87"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041928172" evidence="1">
        <location>
            <begin position="19"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="269" mass="30126" checksum="8B9718AF13DBB6F5" modified="2024-05-29" version="1">MINKYVLGGLLGAAVVGTFLWNDEEFCNDVKALWSKTKERYKLKLQESFIKEKLYDVERNDSINRPELDKDFEELSKKIESLPIYETKCSQNIECFPEESSNAIPSLPQTNVLLSEHNISDGLREDISNDVDERNQKIINNDVGAVKIESEGNQGTVETESEFSNISEILSIEDNTQTIINTAEHDSVRLIGLDVRKTPSSADSVTSSELFLLAESHSQLNPNIYTQNPELVRSYSTESSVASDDSYENISTSSLVGSDEWQNLSDLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXS1</accession>
    <name>A0AAD5TXS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000562">
        <property type="protein sequence ID" value="KAJ3215189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXS1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="98" mass="11416" checksum="392354B91591B289" modified="2024-05-29" version="1">METLALHKLELTGTGVWYGYTRQNSLEKFIVTRKKEEEAQLYEAIREESLVAFEAYKNRLEAEAGEKDGVTTDSDSYKFNAERWMNWAIARSDSENKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXU2</accession>
    <name>A0AAD5TXU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000582">
        <property type="protein sequence ID" value="KAJ3214923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXU2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="215" mass="24340" checksum="A0C66AA231D5539E" modified="2024-05-29" version="1">MTKSDQTITEQISQTASEMYNKVKNTVMPEQSKTAGDKLDEGISATKDKKDSAADQTKGWFSEKSDQANNKVQGATEGKPIGTKVKENLEGAKDYVAEKADNVKSYRTELGIGDVCRGTWLPEYHLQQSEPYCFGYPYVESATEGKKLFERYFGILFDDDDLAKAVESDETITLDEKEEEETENELSHRLTSIIREHFILQTALYFFLKKDPGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY88</accession>
    <name>A0AAD5TY88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000475">
        <property type="protein sequence ID" value="KAJ3216490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY88"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="555" mass="66006" checksum="E3C38034BEA6D09E" modified="2024-05-29" version="1" fragment="single">MNTALNADFDLNGFEDFVENYTSKLNKILNGEDVLTEEKEEEELKKNKLKENSTKKVSKMVKAPTIDYKKFDGITESTELVEKGEQIKKNLKADFDLDQEKILKSGNEFFKKNLFREAIKEYSVGIKNYEKKNYKEEDINLKFFLNRGFSFQKLNEFFEALEDFNCCKNLLEKKKLSKSFDFYNKFEKEELFKLELKIRWRRAIALKNLKNYKEANFEFNFFKTFNLNKKNFKNEIEIFRSFVNVFELESNLKDIEVELNNAERTELEKNTSKGTLGLPNFSDSDKLQIFKLFNSKIINSLKSINSLKELKKQEPVMSNNFILLKELLEFDKIDNKFAIESELKNLAIKNYVVNEFNIFDELLKYSNAFNLTLISTYLNYFFDIKYLSLKQLFKNSTDKDKLQYSKSILSIYYEKELHAVNNNIQNYNFFDNFLTSLIILVEEDKEFFKVVNEALCLNFEIFEFSVNYLLSNLDPMKNSKEAQFQNYTELLQVKLLVFFSRLLQEPKEILVSYIFKTFQSANFKEFEILINKVLLEDDKTVFTDHIQGLRKFKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYF5</accession>
    <name>A0AAD5TYF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fcf2 pre-rRNA processing C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001459</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001408">
        <property type="protein sequence ID" value="KAJ3203588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYF5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="141"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3203588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="269" mass="31422" checksum="8A819AE9D399163F" modified="2024-05-29" version="1">MNIEEIEKLDIYLEAAKKSISEATENIMLLEPDIKEKSKKKLSLNYLDEIELEKELKREKIETNNKKKVKESMATKKLDTSGPYLQTNFETGVTTLKNSILSLETNINQNELLMKNIVEAKPVVPPMLQEDPKKIKEKTIETAGAKWFDMPATEITPEIKRDLHILKSRGALDPKRHYKKDNKTGLPKFFQFGTIIEDKADYYSSRLTKKERSESFIGEILQDSEKTEYFKKKFNHVQQKNMKSLPGWLQKKIEHQRRKGKKVMVPHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYK6</accession>
    <name>A0AAD5TYK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stabilin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">STAB1</name>
        <name evidence="2" type="ORF">HK099_007507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000731">
        <property type="protein sequence ID" value="KAJ3213249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYK6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="9"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="147"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="296" mass="34178" checksum="6D01D7B599B06E59" modified="2024-05-29" version="1">MAEIPQCESNDILCTLKRDHRFEKLSKVIEINENLQKALLKKDITIFAPTNECLDKLFKVGNANECDLEKILMYHIVNQVLELQDMYDHQLLDSELYSEELQRNQKIHVRKDLGAVTLNWNTIVDESGFKTSNGIVHPIDFILFPPYTLLDQIVNYSSKCSTFASALRFCDLSHDISKRRVTCFVPTNEAFKTLDSSDLIYLFSPQGRDDLKKVLQYHICDDVLYATSLLNQNKKLKVKTFLNAENLSVEFKRLNLKTGFEKELKEKLVFSPNCHKVILNDGEAELTNQFDCLSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYT9</accession>
    <name>A0AAD5TYT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PPIase cyclophilin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000917">
        <property type="protein sequence ID" value="KAJ3209914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYT9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF6">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="18"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="136"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="334"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3209914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="447" mass="52432" checksum="A362831880301787" modified="2024-05-29" version="1" fragment="single">MSNVYQNEPPTKGKVILHTTAGPLEIELWAKEIPKACRNFVQLCMEGYYDNTIFHRIIPNFIVQGGDPLGTGEGGESIYGKPFEDEFHTRLRFSHRGLLAMVGESEFPIYPTTITSAEIVADPFEDIVPRTTPEEKKRKKLEEERLNFEIEQAKKKGKKLKKNLNLLSFEDDNNNEEIHDLENKKIKKFKSIHDISDDPSFLKEAVAFNVENNEEFNSKKTKKLKHEMNFEDENYEIENQVLLKKEKNAKMSIIKNEILSLQKDIIEQKKGKKERKEKKQKKLSLIEEMRSQYDKNTTSTIIKNKRGKKVVLDEDDLLERLDEFKNKLKKGSKLLESKKVKNEEEETLKKLEREKKKIEDELDDSQLCKVHRWKNCKTCFDEDEILEEMEEVGEDWKDHSLNFVKEKANVYEPKLDDYTFIDPRLEAKTGVVLNSTEIRKKKEILDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYU9</accession>
    <name>A0AAD5TYU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF125-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000911">
        <property type="protein sequence ID" value="KAJ3210021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYU9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02432">
        <property type="entry name" value="Nodulin-21_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3210021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="28534" checksum="A0D635B0B848E2CC" modified="2024-05-29" version="1">MSERDRLLPTSIVNSNSISHTLNEDTESVHSTSSYGHEHFSSRNPWLRAAVLGANDGLVSTGALLLGVVAASQDNVENSVLLTGISGLVAGSFSMGLGEYLSVSSQRDTELADIEKEILEHAKGPYHRKKELEELTQIYVDRGLSYELAHQVAVEFTKIDPIQAHVREELGIDMNDLTNPLQAAVASVFTFAFGALGPLLMVVIFQDRLARLISVSVMSLVLLTFFGGFGAYLGGASIPKGCFRVGFGGSLALAATFGVGLAFGTTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZS0</accession>
    <name>A0AAD5TZS0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Resolvase/invertase-type recombinase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000620">
        <property type="protein sequence ID" value="KAJ3214449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZS0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="entry name" value="Resolvase, N-terminal catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051491">
        <property type="entry name" value="Recombinase/Transposase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36172">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36172:SF1">
        <property type="entry name" value="RESOLVASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="Resolvase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="98" mass="11022" checksum="B626DA9F6084EA4F" modified="2024-05-29" version="1" fragment="single">MQEHNNGQYSSFHVIQDIGSGINFKRKGLQKILDACLQKSIGTVVVAHKDRLARFGFELIEYIIKKAGGDLKVVNDDFNKSSEQELSEDIISIIHVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U019</accession>
    <name>A0AAD5U019_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000449">
        <property type="protein sequence ID" value="KAJ3216989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U019"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="966" mass="107968" checksum="97557B94E801B1FA" modified="2024-05-29" version="1">MNKKTLSLLVPLVASTATSQESFLLSKRGVGSITKDCSVLSKCAAHHVSEYDSDWTCYNRRKNECSTPLVYSVGPIEREDDDYLLSKVYCWDGNIFNCPSFNNESPVDPEPPKQKLHCYQGSSTYREYIYQYEVYTETGGPKSCFTGELDGVEYYFDLPTADCGSFLDSPNTPWKKTHCCDTNGCNVPRKFISCYSGSSSNPEQMEKVEAATDGHSCFVGKKDNVFTFANIASEECDALASKSGQYEAVTCCKNDFCNNPADYKPPAEEPMPQNYTLTCWEGSTEGASLVTANSDKLLSCISGKTADSWIYHYLPTVECSKYLAGGEYSKDFTDVSCCNTDGCNKPTEVVAPLPEYKSITCFDGNTDNMEGIVEVVASPDMYGEEVQCMTYSTPTIAYFFAVSKSTCEYYQSLNYSYGYTNVTCCDTDDCNKPVESDFIVSDQFSCYFGSTRNLTNVYKSVYDAFPYENTCFSGTRNGVVEFFGTDASTCYYYQNSDYIYQNVTCCTTTECNKPLPASEYPPPPKTLKCYKGDSGNLDYIYEEELPELDWNGEKNTCVTETNTNGKTYFFGAPASVCQYESQYVSYDNQNYTCCNTDLCNKPVGPYPGPTNNITCFSGYSGYGFDYVSEYTISSYNNETLACFSGTYYDYTYYTATTATECGNYGWYGYSNVQCCYSDNCNAANSTTPTATPTSTFPQETNWNNTNWNNTNWNDTYWNNTENTASIACYSGSSSDLFDVTVSYHDYYSDNPKSCFIGTIGDETYFGVKDSSSCYGMLNGTMETMYKNVTCCDSDYCNYPVGDYTSEPTSSLTCYSSNDDGYLNSDNKSKTKYNSENLQYNCAKGYNALYGGWIYDTLDSETCQYYLSYVFDEGTGSCCDSDFCNQAETQPILQSCNMGSSDAPENVYAYQVTEGYSCYIYSYSEVYYFGILDTSSCANYSEGGIYREWYPDFKCCTSEDGSPCNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U040</accession>
    <name>A0AAD5U040_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotidyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000327">
        <property type="protein sequence ID" value="KAJ3219798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U040"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42883">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE THYMIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42883:SF2">
        <property type="entry name" value="THYMIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="280" mass="31991" checksum="6C9BF7B8B9FB84AF" modified="2024-05-29" version="1">MESNLVSVLFLVAGYGTRLERDLVNDGTKNNLLGLPKALLPLNEIPLLSHWMKLLQNPSIQSHLITNDKFYETFKNWSKMFEINENQLLNDKSTSNDDRLGAVADLELAVEKFNFISLQRDCLIIAGDTLFLKDFSLDQFLKIKNDVKGVLVTCVNVTDEDTKKMGIIEIDHKDTVKSNGKVCYRVTKLMEKPGPELTKSRLAVPCFYYLPWNCLKYLNIFMDEKKLLKEELKEFDASGKFFTWLVDKFPVYTLEISGRLDIGGLKSYCEADAYMKNASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0F7</accession>
    <name>A0AAD5U0F7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD repeat domain phosphoinositide-interacting protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008154</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000868">
        <property type="protein sequence ID" value="KAJ3210879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0F7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3210879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="45448" checksum="86198086778BC479" modified="2024-05-29" version="1">MNVCFNESTTHFVAAASTGLANEATFTNLFSNPGYQIYNSSSLSAVQKMLKIETSKNLTGLSSMNKILHQRINSGTQFETFLAKEQRQKEVFKRNRLILVLPALQVGQVKILKFCNKFNADKNVVEVDIERQPESSIIIAHKSKLRCLTLNDNGDILATASEIGTIIRVFCTKSGTLLNEFRRGYDCCFIHCLSFNKDSQWILCSSDKETIHVFEMKEKENSAALNYKNNNNPPNTTLKNNEGLLKQFKSTLKQSNNTSFAKFKVKSKQHLVSVCSFYDKNLNTNINPLDIDKELKRKLHFLIIYSDGACYQCSFDKTSKVTNNSCHLDVFKFLNKDLGLSNSWGSKNNYLLDQEIDFQMFNNKNSTANTVPSGEAVNDFENVAPDNGILDDNIAVDMYDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0H1</accession>
    <name>A0AAD5U0H1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000408">
        <property type="protein sequence ID" value="KAJ3217835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0H1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="127" mass="14598" checksum="46A95C6948B1F8DB" modified="2024-05-29" version="1">MLQKHTHRSETMDNSAASNSNEVKIEIKEEKTSGTKDENVEKKVDKEAIFPSPFVVKPKEFILDSLIYSKLSLGILDLYAYLFKLDGRLQKLKEKERLRKEKIIGEERLKVLSSLPSVKNLPLPKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0L8</accession>
    <name>A0AAD5U0L8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000517">
        <property type="protein sequence ID" value="KAJ3215831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0L8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="165"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="347" mass="40615" checksum="EC3406F274FE77BE" modified="2024-05-29" version="1">MKIKICYVQQIAEKVSKRVTGVNSHIFRSDLGNDANNESNINLREKTSDLERINFKNLQKQYFQEKKLNESKIFKIENESKNLENSLLASQNEIKLLKRQSKLLEKTLQTNLAIMDDTKNKNLEEYQKILNLLETERLISKSLRIDLEKSTKLHLIAENNLRDSLNQEKRNNLNLMIELNAYKSNIKSLKEEQIKLQNKEREYLLKSNYCSRENFASRLEICQSQCSPTSESAERYNKEKFLELKKENLNLKNKFEIMQKSYEKVTSNTFNANCEIRGGNIPRQNLTAPLESEDFLLVPGSFKSNKPGIVSRIKSKKELSRKTPYLKSTPLPLKTFFTNTERKFKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0M6</accession>
    <name>A0AAD5U0M6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005796</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000469">
        <property type="protein sequence ID" value="KAJ3216603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0M6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF57">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-hexosaminidase bacterial type N-terminal" evidence="7">
        <location>
            <begin position="27"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="6">
        <location>
            <begin position="165"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3216603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="341" mass="39511" checksum="6E75692205B327FC" modified="2024-05-29" version="1">MEYSDLLTNYFFTSIENLLNISVSDLLWPLPHSINSTNYPLELIKFDKIELDDCSLSDETCKTLLNSLKITINSLRSKCNYDVTNSSALLFKIKFKIDFDDILNPQQLLHVDESYVLTVSPKLMEIQAKTRIGFIYAMQTLSQLVISTKKNCYIAAAQIIDKPRFSHRGFMLDSSRNFFSVNDIKRQLDAMFYTKLNVLHWHIYDAQSFPIKWEYDGGRLYKNSAYKWDDGSLKVYSKNDVKDIIDYAFQLGIRIIPEFDMPGHTTVFSKAYPEIMKCADFGPGFDGQKGINWVKRRCNQPPCGQLNPDAEKTYVIIEQFLKDMGEWVTHLIAFESIFIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0T0</accession>
    <name>A0AAD5U0T0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000498">
        <property type="protein sequence ID" value="KAJ3216098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0T0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="236" mass="27060" checksum="FBFBB1FA307D7014" modified="2024-05-29" version="1">MLKSILACEGGYWVYTPCTKNTSCKRHRNTVYCDHIKKKKQYDAWGYEDGEESDAENNDFDDEDWIAENDDFDDEMENGKEKNWRDTRKKWNSDENEDSDNEFEEWEFERPGNDNENEDPEEIENGTAEEENVDPKPKSDSSEPEKPNEGVLAKTTQTSKPTDVKTESTPIASTTNSDVDFCINPPVSKVPSYTATLQKCFKVCCSMELNPGLKNSCNRQCQILDDAAFRAQVWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U156</accession>
    <name>A0AAD5U156_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006457</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000558">
        <property type="protein sequence ID" value="KAJ3215234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U156"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="372" mass="42358" checksum="AA3DD869337B41AC" modified="2024-05-29" version="1">MKCKHCSQQFGKKSQLDNHYKLLHQKIVRIAVNLLPNATAFSEVTRSNNEFHCEAPECDYSHKNPNAFGKHCRKCEKLKNWLEIGRNAVSINVVNVDTEVRENTNNSSSNEIIIETEENNAEGILCENEEEFEQVGILERLNLGVNIQHHLLIDVEKNNVLYFTKFDGFKRFIYKRAKKVQVKKKAAFNEVRSFLNALVLNNAIGNIDNSDLQLLLPAATGNLEFSVGENNYDLVKPIAGLKVYDGFQCASCCSDSANNNRKPFYCRNEKLMKQHMKTVHNIPNLQYSVCKVQKAFSNNKNPYKKLLNSYFGVKLLAAEKIVDNPNQIYYYVDVEQKATPEKIVGAYYKEGDAVLPSNALSYKVKSDSNVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U183</accession>
    <name>A0AAD5U183_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000276">
        <property type="protein sequence ID" value="KAJ3220747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U183"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF108">
        <property type="entry name" value="PROTEIN CNPPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="294"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="442" mass="51515" checksum="A1CFC22456E01464" modified="2024-05-29" version="1">MYSITSVQALNAIQNDKAFKQNPLKNVNYLHQNGYTMQSNMLPYQQQSFTYFNYVNDVSYIHNDAPNGVFTAIKQCSPNFDYKSSDQNNGFMNKKIQIRNNYNNFVKNASQNTHYNSQPSLSHQQQKVSGSNNTTISLSNCANFDNTSYLNNLINVENEKKTKFTLPQQKKLNLNKTCTVVEKRLCKNTLSDSVNQYFKQLKVFIKQKNDKLNCKFDFPKIFTLTSFNDLTQNFNVDLFDGNNTFESCFFTHSNLQSDIIEYTDYFLSKNFPIVPEKNSNVLPNNISGKKPLPSLEHFLKAIFKKTKISISTLVTALIFLKKLKFNHKNCKGSEGSAHRLILASLIVASKYLFDDTYDNKAWQIVSENLFCLKDINKMEMEFLTYLNYELLVTWEDWVSFCEDLEIEMKAYYYKLHGNVERAWKGPLHFEFKIWDEVDEMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1V8</accession>
    <name>A0AAD5U1V8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD synthase</fullName>
            <ecNumber evidence="2">2.7.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">FAD pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FMN adenylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_003185</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>FMN + ATP + H(+) = FAD + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000212">
        <property type="protein sequence ID" value="KAJ3221733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1V8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23948">
        <property type="entry name" value="FAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293:SF9">
        <property type="entry name" value="FAD SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293">
        <property type="entry name" value="FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="13">
        <location>
            <begin position="106"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3221733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="216" mass="25029" checksum="480E4C18D59FDF3C" modified="2024-05-29" version="1">MIKLNASIEAIKKSIKDYGIESLVLSFNGGKDCTVLLHLFFEVLCQLNANNDSVLKINTLYVASPNPFSEVTEFVNYCKKRYDLRLFQYETQMKQALQIFLDSASQVQAILIGQRRSDPYSSHLTTFIKTDNGWPEIMRVHPILDWEYDEIWEYLLENGLPYCTLYDQGFTSLGSKNNTMQTLCLQNKDRFCGYDPAYLLKDFSKEREGRLDNVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U200</accession>
    <name>A0AAD5U200_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000215">
        <property type="protein sequence ID" value="KAJ3221682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U200"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="506" mass="58433" checksum="7CDDB6C53F951711" modified="2024-05-29" version="1">MLKNSRQLTQEELTEWESAFAPRPKVFDDRGITPSPPNREKSFTQYRIERETDAISKTPSPTPLPHFENRNQKPTSSKMERQFSSPTSSAEKNSSIIVNKKFSTQSLNQTRIPVPVNYDMDSSPTFKKSKSHINFTNGVNGSWHESDNVNSNFSKKNLVPLTSSSANTTLSPVPIINNSYHLPNNFSVMATDDNHLESDSGKENCNKLEYVNKDKSHFRRNSENVDHYNTQQNFNHNRRKSEMVLSNSSKNMSSLKNLASLKLGTQNIKTSSPFLARATSTSKQVMFNSTILESPKITQRIDPFEDFGNMTDDNNEVVLINKINSIEEKMSVLTKQHKDFRSILKNLVKSEQLKYLPSILKIQKVFRGYLVRKKLFEAKALKKHVEILKIKENTRIITLDMLLFDTRNLSKNLANKLLLDSDLEKVIKVQALFKTFLVRSRIRKYLIVNFSATKIQRSFRKYLIKKKNLVKLLQIRSIKQENEIRTLNLKVEKLTLMVEELLQKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U212</accession>
    <name>A0AAD5U212_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynein regulatory complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Coiled-coil domain-containing protein 135</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Coiled-coil domain-containing protein lobo homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">HK099_003463</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DRC7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000227">
        <property type="protein sequence ID" value="KAJ3221485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U212"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056290">
        <property type="entry name" value="CEPT76/DRC7_peptidase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033551">
        <property type="entry name" value="DRC7/lobo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056292">
        <property type="entry name" value="DRC7_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056291">
        <property type="entry name" value="MORN_DRC7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35249">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35249:SF2">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24656">
        <property type="entry name" value="CEPT76_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24671">
        <property type="entry name" value="DRC7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24667">
        <property type="entry name" value="MORN_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0221">Differentiation</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0744">Spermatogenesis</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="15">
        <location>
            <begin position="214"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="CEP76/DRC7 peptidase-like" evidence="16">
        <location>
            <begin position="413"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein regulatory complex subunit 7 MORN" evidence="17">
        <location>
            <begin position="537"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein regulatory complex subunit 7 C-terminal" evidence="18">
        <location>
            <begin position="851"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="501"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF24656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF24667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF24671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3221485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="964" mass="111498" checksum="D281D66DFEAA8496" modified="2024-05-29" version="1">MEEVNADQQQKEENLNDAKPVEDSTSIKLAQEMVTDVITEENTTNPLQTTVENEPTIRSQDGEQIDQSEQIELQNLNLEPSFVNNLEITDDNHLTNSTRPATSLNNSIVDSIDPHEMQYLEQKQKKKESLKQSLTDVANCSKSYYEISEKEQIVLNYVDNFNRQYTHLFPGRKALLLSPPNEFGVKKFICTTIRPTQLPYKELYDYNGCARFVADYLSYIPLDPPHELPATIPSPTYTLKIQEGNCFDLSVLLTSLLRGVGYDAYVVSGYASQDITLMDETKTDVAAMEMMAAALGFHSNYRENENFWMIGEEIEKVTNTDDKLKQQQQKKKSNSKPTSGKSLHEDHNSLLEKQRIKYKIKPQKKLTSQFLLKSEQKKQILEKSVAEKKRIEVEIQNSNNDDDEDELKGLRIHAWVLVLPGKREVAEAFFIESSTGKIYSTENKNFLGVESVFNSANYWVNMQVCYDGMKGISLDLGDNSKWEFVLLDNTQPGATGNKNEQDEEEEEEDNNTEILDLPKSWVDRLTISKEDFQTRCPSGTKTIIFKSARLEMFAEYHRDDGMVARISFFANEEEKFNGEIKELFKNRKDKLWQRIRTPHIDKIHEYFEPGRPHGLKNHIIIEGKTKEMHFYSSARSDGLVKRVDEFNKVIEYFTSRDDRLIYRSVTFETHMEAEGEQRLPHKLTEKFERNPNIPASEDPAKKTCFLKEEKIRIVYHLEDGRIIPSFKEFKKPTAEQKGNFMDLTNGFEVDPYVPLPKKQHLCALLHQLVRGEQSCLQAIKGSDREMKEILIARKAEEKEITLAISVYDTIRNNSKFPSEEEKEAHKGEQEELKAADLDYLSPFLVNKIHSEKLSKEDAMQVRDACLKSMKERLVERANIIQSRLDEVSAEYQRRQLAYSRNADMMTVEETEEYVKFCNNALFKIHILEKRLAKHKEAAPDRYEDLDNRLHADRRLAAAYLQSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2E1</accession>
    <name>A0AAD5U2E1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000195">
        <property type="protein sequence ID" value="KAJ3222041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2E1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="683" mass="78463" checksum="3925E1171D3DB908" modified="2024-05-29" version="1" fragment="single">MGETQQRNYSPAVKKYTTLALMNGWKSNNEVFPITLENLLNYINLEISRVVNFWAKEAIVEEYKKFSRSTSTLNLKKLFPIPIKKLEKFLDYLIENYLKLNKIDYPLLLLYLDQLKRKHKSLGFNLNLSDPVIQAKLYPFQISENTMLKSNNLNMGNDDDFCNSIGVKKRSENSKMSYLMSQQKLNLLVTEMKVMQMKEYFTQLVLSNRWGNSKDKVFPIHLDTLHFYIEMELKKVEVGELTLGTLQIYIESLFIIQSRMGYSVEKLEEFSYEKLRNFVHSLRALKKRNKNLSIEEDFGSCSEVDEDDENLELEDLDMVDKHQSENLQEKLSVDGNFFFVIFIFNNKAVLVGSEDDMDTHESFNNNDGSYFESYEAFQSRKKNDTININLNGNTRASRKQLKKQQLLNNEEIEFKLRNLPKISDFILKSSPAPTFPNTLSTGKYTNYSPLLLQPVPLMRSNSSLSLASSNASATVPISSPVSLKVKCESKQDATSSRKKTYEKLATAQGWSKPGEHFPISLENFHKYLDYELNRVEEGKIMMSSVLHATHCLAKCHGVLGFEWDNVRYHPETRRKLRLSLYDVKKVSTIFVNELSPVLMKEERLFSDKILNEQESQNALQITKSFNPITQEIVDINQVELPPIMKTFNAIPRTSSLPALSSILSAVPSLSSSTASLPSLSSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Q7</accession>
    <name>A0AAD5U2Q7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000191">
        <property type="protein sequence ID" value="KAJ3222110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Q7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="36740" checksum="2A5280C0113BF629" modified="2024-05-29" version="1">MVNVQSTINTSTNERKLKPKLSSLVINYSNDQIIPSSRTSFEERLSSNLNNLNIEYNYTPPASPQASPPTSPSANSTDILEKQQKDLQRRLEYISHMTTLSPLNQPILTSKSSIKRSSSKKGKNKNLDPAISRWKSILGPVNWDGILKTLHSTSRTHLESEFYSKILYRKLPVNHYIRVTSPDHEITHNCQRCLEEQDETIEHFLCLCGNAQKFWTIIGNFISKILDIKVDEIFEDETKLRDVVYFFPKLRENFDFDEDQLTVLTVVHSTALWGLWGARSHKDPVKVSNVNIAWNYFESRLQARLSLFPSEFLNKFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2T5</accession>
    <name>A0AAD5U2T5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LUC7_2</name>
        <name evidence="3" type="ORF">HK099_002284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2T5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="286" mass="33867" checksum="CC0743DA2FB78137" modified="2024-05-29" version="1">MAAAQRKLLEELMGTAALKGTDEVNNYKEEKICKSFLCGLCPYELFTNTKADLGSCEKVHVEKLKKDYERDLENGGIDFSLEFLLNLKTFVDDCEKKIRFNKNKLEKSFEEKKINTLVSEIADLTNEISNVYFIGESLIEEKKWSDAGSILEKADEFMRFKLSKEKELVKLSQNFLKGDEVNTLRVCEICSSFLSIYDSDKRLSDHFSGKMHVGFLLIRDKIKELEEKLVIRIKTEDCVKSYRRESLDSRSYEERRERERDRDRRRDDYKRESRRRSRSPYSRRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U330</accession>
    <name>A0AAD5U330_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_001895</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000159">
        <property type="protein sequence ID" value="KAJ3222790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071539">
        <property type="term" value="P:protein localization to centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01100">
        <property type="entry name" value="APPLE_Factor_XI_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057537">
        <property type="entry name" value="C2_C2CD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21254">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21254:SF1">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25339">
        <property type="entry name" value="C2_C2CD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57414">
        <property type="entry name" value="Hairpin loop containing domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="12">
        <location>
            <begin position="395"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="627"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="667"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2092"/>
            <end position="2124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2138"/>
            <end position="2172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2185"/>
            <end position="2495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2610"/>
            <end position="2638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2669"/>
            <end position="2698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="667"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="2092"/>
            <end position="2102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="2155"/>
            <end position="2171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="2194"/>
            <end position="2205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="2206"/>
            <end position="2253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="2287"/>
            <end position="2299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="2300"/>
            <end position="2315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="2326"/>
            <end position="2376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="2393"/>
            <end position="2407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="2408"/>
            <end position="2418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="2422"/>
            <end position="2461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="2478"/>
            <end position="2490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="2623"/>
            <end position="2638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="2669"/>
            <end position="2682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3222790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2767" mass="315467" checksum="5D6F01BDEB6B56C0" modified="2024-05-29" version="1">MNFLSYFTSSKATVNSIFSRKIKVFLLINFCLFILFITFYNNNTKLKVNNSKNQNKNNIPLKNKLHYKPLKNVTKKVLNSHNTGSEKKKKLQLKKQKISNDKISKTLKKYDQFAVSIKTGRGSALNRLPIQLVTFLQDVDINKVLFIGESPNITVGNVHVEDVCTTLYDNFTEQPKDWKVSMELLQKEVKENKIPKPGEKTEGWKMDAHKNLPGFVKLYNKFPDAKWYVMLDDDTYMFFGNLELLVEKYNPNDEHYIGAGTLFNGCDGVTKFGDGPEFAHGGSGIVISQGAMKKMIKNVNTCILRYRDCWAGDGILLKSLPGFNNITPDKFSFPKNACERPLTFHHLLVKHFQKLHLISRNKLKAVKPDSNVYFSTPNYADIYEAYNSYDESNLYEKDFDRKGSDYKDVNCSNAETCQKICSHEAKCVAWTFLDNQCWLKDAIPEGETVTGHISGVEGASEFEFVLSIPTVKLKGKPTVTFKFWGSQEEFTFTPNTLASSIKTSEFIQKIDFGVLENDNEVYCTFPISSSLKLFKNYLKDMKMFYFSIFNYGKFVGQSEFYNISKLIQENSVLTILPIYSGKNNVTEIGELILFLAIKEKKSKGKENWESQSHKPYNLSVNNSLSDIVSPIPDPTPSSPPQKKTNEFSTSPLQEIVGNSSFSNSPLNFSTSRLNSSNSPSPAPRASSTFESLTPEKLNHQRKNFNKPEVFSEYPQMEDMLPNYKPKIDNNFNSEVKGEDSSKRFLWDQIENRMKKLDNDINISLRNENLDYETLQSVMPSLSDDLLAILDDDANPVELRDAAKAAASYLEDSNSEDNESDLEYHDLVDDDLALNMSNWEPKKRNPNVMTNKGEIEDALSDDSNLEHLELESSGFNQYDIEKNIGSPKFAPKKKKEKIFQESNNLDFTNDIHSVIIKMDRVQVPVTILENYDIGVPNVDAKYNSKYVTRSNWTEIQCEVHYFIPNGDSDQHSGNVVSEGIPKFESKDDNKFLVIKFTNHRSIISGKNALCWKADDKLDFKIIFKTKKRYNVKKTINSNKIFTSTGSISCSEIVDSVKNNKYTGHIPIWTKSSFVGDLTFKLEFVKLEDMTKNVNKEVIENKRTRIYGSKKFNNQPEDTTSDNNRAVHSQIHQLRSHNNENPDFVPVVEKLGLQKPNTALPNNVSDAAKTTSTPSKLSLNHTPLYVQLNVGKARAFSLLNENVPTLLYLSVRLFFSSVIESPTVLYSRSSTSVEEADFQFSYSVPISVDEEFIKQWGKSSVVVEVWVIESNSVLDEKFSKSTFLKSKELQVDGGRRLLGLLRLPVGFLISAAIYQNSEKNDRQILVPAAGPMPYILANREYTVLDPFAGGGARAFVSVEMKLGTLDQIKYVEPTEIEQKSLRSKSPEKKMTTPVFTPTKLRYSPTKVKSKETKLVDKDTGMETNECDIQVTIFKMCGLVYLLERYFIENNKQFNFDDENFVIQSYITLDIFPDLSIDGQGDDFFLSKDCENDLTLVKTDVAEGSLPEFDHCEVLTLEGIDSNLLNWIRNGGRAKGKLFCSFQKKDDNFQFEEVGRFTFVLRDIIDRPLGINNLWVPILSPFDSDEVEIHSAVNLSVKILSGFDFGEIIDAASVKLSKTYNPFYLNVNITGLDARLETKDMNDYVFFFKFLYPVYTPEGLHIETKISSEYNVTCYSTKSDGVLEMTVNFKGAFHFDGNPATYQWFRDNNFTIQLWRMEKDFEKKKLYLGSAFIDVWRLLDKFKRSFRKIYSKKNSATNEKSCSMEKDQFLLINENSPDLNTCYLKAKISILEKNSNSDAVLNEKFNNQIGESSFTKMARTPSPTKSNFVSCSTVDDITADLNIKLLIGVEEFKLHSKVQRNINLRGNDTFFVAFEWSKASNFLSKTYKTAEVKLDGKFTEIFEIKLDNFNVDQLNTTINFKLFKKNSKGEVKELGHCNVNLSDLYFLELIYGWYNLVDVDTLSIGEILISVKPDDSGLLLLKSTDFDVLKNGGDSKKSYQKENSEFHSDSVKSNLRADLENLQNFNKKAKESLNLSQKLKSNEESREEQFVVVEFNDSFNEKMDKTLNEVIKVLKVNDANNKKYEKILKNIEEHATQTEKMDRNNYHKNKHSRSFTDNSAVNQRKEDEILTIYSTKDGENEKLTKRKFSQSPDKERSMSINEDYSTPLNKMDSTQLDKDLTESKEFTLPNKNYHFASSPSHRSTSPHRNNATYANDNSHNSLNKVNNFSPNKYNPTSPTRNQSGSPINTINKNHSTSPDREKSASPKRNHPFSPHRENSTSPNRNHAASPRRDGSTSPDRNHPNLSNRAYSASPNRNHAASPRRDGSISPDTNHPTLSNRAYSTSPERNHPTVTNRAYSTSSDRNQPTVSDRAYSTSPDRNYPTIDKRNKSSSPANRNQQSSPSRNSNSPKKYDVFTDKLRPVSPSRTETVAPSTEQARYNRSSSPDTIKSTKFKNTQPSTSFSEESKPLNFSHKPPSSPSQPRASASNSNRNLKVIPKKNFKSEVSLSRVKSPEKYFSATTNYDTTAKSYILPAESLNFSNEQGRDGKNEENFKEKDIFNIYLSNNHDPKKYLIERRSKSLDRIGSRTNFFTSYEKQSNNFSKSIVRIGRSRSTSPHAITKPSVHINSVGQSDSQNTNTTQFSLKNSQNEAFAAKSTKFCECFKFQEKIPTSQHNPMEDNSQFLDNKPNTEENSSLSSSSEEREVLDFQWLEKKRNERKRLIGSWKDVGSFGKKKTTTIEQKTLKEQKKFVFDTSNKSEIDRILKIYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U343</accession>
    <name>A0AAD5U343_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protection of telomeres protein 1 ssDNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002247</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the telombin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000173">
        <property type="protein sequence ID" value="KAJ3222493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U343"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000783">
        <property type="term" value="C:nuclear telomere cap complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098505">
        <property type="term" value="F:G-rich strand telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010521">
        <property type="term" value="F:telomerase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032210">
        <property type="term" value="P:regulation of telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016233">
        <property type="term" value="P:telomere capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028389">
        <property type="entry name" value="POT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032042">
        <property type="entry name" value="POT1PC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513">
        <property type="entry name" value="PROTECTION OF TELOMERES 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513:SF0">
        <property type="entry name" value="PROTECTION OF TELOMERES PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16686">
        <property type="entry name" value="POT1PC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Protection of telomeres protein 1 ssDNA-binding" evidence="8">
        <location>
            <begin position="173"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="322" mass="37035" checksum="3D2EC9D6FD804233" modified="2024-05-29" version="1">MTTDENSIALEYYNLCKAQNNFNCLFDLQSVKTKFDVQILAVAIEKKRPQKTKGTDYSASYLILDPTIADPLTLNVFKPNLKAFPTLNAKGNLISCKINIKEFGGKAQFTTSKPSQLAVLEKNSSLSITDKALSPLVDFLLKWIDSNFLQSDTPIEGRLSQKLSRRLISLHEINYTDNGCFVDMNCLVMRIGTFDGKKAEILVTNFTENENVMFNSSSDEKMSIAVELRKLNQIVFQKSDAFALKNCKNLFFLINLWGTEGEKYQNFLTEKKYYNFRNINLRVEENESCEGHLFPDQKYPNKHFVIEIYKGDEEYEDLERYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3D4</accession>
    <name>A0AAD5U3D4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Component of the SF3b subcomplex of the U2 snRNP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BUD31</name>
        <name evidence="5" type="ORF">HK099_005680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BUD31 (G10) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000454">
        <property type="protein sequence ID" value="KAJ3216906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3D4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001748">
        <property type="entry name" value="BUD31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018230">
        <property type="entry name" value="BUD31/G10-rel_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411:SF0">
        <property type="entry name" value="PROTEIN BUD31 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411">
        <property type="entry name" value="PROTEIN BUD31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01125">
        <property type="entry name" value="BUD31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00322">
        <property type="entry name" value="G10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00998">
        <property type="entry name" value="G10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3216906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="147" mass="17095" checksum="C5701A978A347F28" modified="2024-05-29" version="1">MPKIRTSKSKPPPDGFELIEPTLNDLDKKMRDIENESTDGKRKTEALWPIFRLHHQRSRFIYDIYYKRKAISKALYDWCIKQGYADQALIAKWRKQGYEKLCCLRCIQPKDTDFGTTCVCRVPRNKLEEGRVVTCMHCGCRGCASGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3S1</accession>
    <name>A0AAD5U3S1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000429">
        <property type="protein sequence ID" value="KAJ3217386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3S1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3217386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="48187" checksum="4E66716E75DFA8A0" modified="2024-05-29" version="1">MFDSFLKNLESLDIIQTSLITTIISSISVFIYFYTKENFNKGENTSHILGPGHIPILGSGLFLKKNFNNLTHQLYLYSKQNSFKTFCIKNLFAPNTYVNSSPEVVEHILKNKFNNYVKGELTKERVHDLLGNGIFASDGESAKLQRKTAANIFNVKSFKDWVANIFQNEMDVFFGKLNEYSKTGKEFDLYDEFCKFTLDSFCEIGFGIKLNCLESFEPVAFAAAFDKSQVYLAKRSFNPFWKLSEKFTKEGREGKICFKEVHDFALNFVLDLKNEENRDKRKDLLSLFLNLKNSDGNVLHSDEELAYIVLNFIIAGRDTTAQALSWCIYELSKNPSVELKLLEEIQTNIGNSVVTYEKIKEMKYANACFLEALRLHPSVPGNKRAAIKDDILPDGTFVKAGSYVLWSPYTQGRMPSIWYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U404</accession>
    <name>A0AAD5U404_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Polysaccharide lyase 14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000120">
        <property type="protein sequence ID" value="KAJ3223696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U404"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048958">
        <property type="entry name" value="Polysacc_lyase_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124:SF1">
        <property type="entry name" value="DISAGGREGATASE RELATED REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21294">
        <property type="entry name" value="Polysacc_lyase_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysaccharide lyase 14" evidence="1">
        <location>
            <begin position="96"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="224" mass="25366" checksum="2A546476C7BD83C2" modified="2024-05-29" version="1">MNSAIKCWEQLDFNHCENNKSKLNSSWGLMKDTYGQQNRTVDHDPDPCFKHCKVLKLLYPKGSANPGKKEEGLIRGGMGAYCKPVNLRNAKYCIKGLFGSISDDKPPKASGGAASLESFSTRLMFRENGGGEIYLYVNKDAQHPDFCDKITHYNSTYGYSIGRNSFYFQPGKWCKVRQEVTLNNTEGDNFNCDGSIKLYFDDKLGMEKITRLLLTNTRTSKDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4A5</accession>
    <name>A0AAD5U4A5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NHX1</name>
        <name evidence="15" type="ORF">HK099_000384</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000109">
        <property type="protein sequence ID" value="KAJ3224007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4A5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF187">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 11" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="486"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="571"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="SHSP" evidence="14">
        <location>
            <begin position="34"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="727"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="808"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="727"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="808"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="818"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3224007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="833" mass="95109" checksum="35F1532B6906E710" modified="2024-05-29" version="1">MPLLFHSPASENFLADFIENILTPEQQHELNASKKMGKFHPKLDVLETEKEYLIQVDLPGMQKNEIELSMNDNNILVIKGERKLPLEKKENDKEVLMERSVGSFERRLQLPKNINFEEVEAKLELGVLTLKYVKKPKVDATKKIVISFIKKMENPTDVLESHKDDIEIETTWTLFIFIALLFSILWVSYFLQRNRIRVIHETVVSIFLGMFVGLVIRLYPSDHVIQYLVTFDSNYFFNLLLPPIILNSGYDLKRRSFFRNFGSILIFALLGTMISTFVTGTLIYIFLYTGISGLSIGYLDSIIFGAILSSTDPVTILSIFHQMKVDPTLYSIIFGESMLNDSVAIVLFSTLKKFKGQDISVQNLLSGTGMFAGVFLGSTLIGVIIALICALMLKNSNLYLYPSLESCLVSLIAFASYLLSNGIELSGIVSLLFCGITMKHYCYDNLSVRSKRTTKYMFRVLSQLSENFVFIYLGVALFTMPDFRFLPLLIIFTLVVIMGARYVSTVPLALAINWINVKLYKRDEAIPRNHQLMLWWAGLRGTIAFALSFKIDDEVSGRFKYTLGPGIRSTILIVCVISILILGGSTNFALQYLDIKTGVGSIDHQQSKNYVDEDTDSSMDEESWKELKKGQNSLSPCNSEVESEYSLESIDNDASHWFIDFDDHFVKPMFTRKKNDFQELNSNERFRGSKKKNANSTRRFFFNNNNSGEMGYSSSEEGLMLPRIKEGKTREFGKNKQNEGTKQKQKSNFFSRYYNNEAGPSFSTATTEDKKKKKIFRNDYFKKNQNNLADETEDFRDGNGNIWKKVSSKTSSLKLNSQDNYDNDTTIELQGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4R9</accession>
    <name>A0AAD5U4R9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">AP-3 complex subunit sigma-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">AP3S2</name>
        <name evidence="12" type="ORF">HK099_002011</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase IV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000163">
        <property type="protein sequence ID" value="KAJ3222701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4R9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.442.10">
        <property type="entry name" value="Cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004203">
        <property type="entry name" value="Cyt_c_oxidase_su4_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036639">
        <property type="entry name" value="Cyt_c_oxidase_su4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707:SF10">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02936">
        <property type="entry name" value="COX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81406">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="11">
        <location>
            <begin position="59"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="250" mass="28372" checksum="80D8E329E9C2B0F7" modified="2024-05-29" version="1">MSFKDIQTQQSMLKEIFALVSKRTSQQCNFLDGTALLGDDIRIIYRNFASMNLLQSKSVYRLFTNVCELDLIFRPEEVNHLLMEVISGGMVLETSISEIMAMNDIKKIPKGVARRSNVILHSISKRSISSVSGIETRWTKMPECEQGAVADFLAEKQAGDWKLMTLEEKRAAYFIAFGNYGSRTPPNPAYKYRVMSWVAGIFGLSVVCWQLWIAKMNPKKKTMSAEWEAVRIANAAEGRHNPFTGENKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4W7</accession>
    <name>A0AAD5U4W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000233">
        <property type="protein sequence ID" value="KAJ3221390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4W7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="26893" checksum="FF8FE0941E356F6E" modified="2024-05-29" version="1" fragment="single">MIEDSNRRSLGLAMLPYRIGLFASITGAIMCVPMIFQFDCVMYFNHHFVTADIPEPKDLETWLENIGARPYTSWYKHRRSERLTKEFPQYDKFILKAFSEGDPLSVREEKYIDPFEKFWENVETLVNNGKGAVAFTTAAQILANNEQENCDISNDPANLQEQFGSYFIVPRTENFTDVNLKFSFSSPLNAENHLHRFKNPLVGGKSNKKSFEELELENELLKKTLNELTLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Z0</accession>
    <name>A0AAD5U4Z0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADE17</name>
        <name evidence="11" type="ORF">HK099_003495</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PurH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000229">
        <property type="protein sequence ID" value="KAJ3221452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4Z0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01421">
        <property type="entry name" value="IMPCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000001">
        <property type="entry name" value="Bifunctional purine biosynthesis protein PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024050">
        <property type="entry name" value="AICAR_Tfase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005492">
        <property type="entry name" value="PRK07106.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692:SF0">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="555" mass="61482" checksum="78F25DE7DC841346" modified="2024-05-29" version="1">MKQKSALLSVSDKTDLTFLATTLHENGIRLIASGGTAKQIRENNIPVLDVSDITKAPEMLGGRVKTLHPAVHGATESASDKKDMEDRGYDFIDFVICNLYPFKKTIAKSDVSIAEAVEEIDIGGVTLLRAAAKNHSRVTILSDPADYKSVLKEFKDNNGTVSEATRKNLALKAFSMTSDYDVAISNFFRAKYAGDGQQQLTLRYGANPHQKPAQVFVNEGKLPFKVLAGSPGYINLLDALNAWPLVKELKQSLNLPAAASFKHVSPAGARARGSDRMSSFGDWIALSDVCDVATAKIISREVSDGIIAPGYEKAALEVLQKKKGGKYTVLEIDPKYEPDEVETRQVYGLNLQQKRNNILITTKNFENIKTKRNNKLPQNILNDLVVATIALKYTQSNSVCYAKNGQVIGLGAGQQSRIHCTRLAGEKTDNWWLRHNPKVLNFKFKKDVKRADKSNAIDLYVTNQIDDKEKFDSLFDEVPSDFTQAEKQAWLKELNGVVLSSDAFFPFSDNVERAYKSGVCCIAAPGGSVMDDVVLQEAENKKIDYVFTEYRLFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U517</accession>
    <name>A0AAD5U517_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator swi6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SWI6_2</name>
        <name evidence="6" type="ORF">HK099_008168</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000087">
        <property type="protein sequence ID" value="KAJ3224623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U517"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000001">
        <property type="entry name" value="APSES transcription factor (MbpA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF3">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="5">
        <location>
            <begin position="63"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="338"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="457"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="714" mass="82051" checksum="1E77B46A1135A5C4" modified="2024-05-29" version="1">MLSSSDLSHEHLYLINPFDHQEVNQQQFFQQQYHQCYYQPPLTDFTHTYNNINTNFQTLSNQIFSAAYSGIQVFEMLCEGIAVMRRRADSYLNATQILKVAGIDKGKRTKILEKEISQGEHEKVQGGYGKYQGTWIPYERGVDLARQYYVIDLLKPILEFDPPIPGVKPTFNNRECLPKVKVYNTKEKDSKEISISKKRKQTVKDAKESNIELPKKQKKSYYEKKKKVDSQLQAPPLKSAHKVQKIRALAKSNEQQNVRQNLKQPVNQISTPSIILNENTYQYPNQGILIEQEELYRPERYKEDLMALFLNENAVFPDFLKNPNPPADLDVDLLIDEQGHTSLHWASALAKTVLLSLLISKKAQINARNFSGESALIRSVLVTNNYNLQTFPIVLELLHTSLYLEDNQNQNVLHHIALLDASEKVEAGKYYMECILEYIARNENGNFNKLVNAQNKSGDTPLIIAARMGHKNYVEQLLEAGADISLENRSGLGPKDFGLDYFFGYNELKYHDELIVECNHDDSNSLNFPLDGFMSNTGILPEQYLEEHNYFLQANAFCLNEVDLKQNYQLYNNSTFNSSPPVKFVFPISKTDEATHSSFKPISLISDNLNESNENEGTRRKLNGNPNKINDEFYNLHNPVLGQEFNDKSYIETELEFTKAHFEDTVIDSFFLDSVLNTFENDKDIGVADISSFLVEVRKQEEKSCIKECDLEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U518</accession>
    <name>A0AAD5U518_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glyceraldehyde-3-phosphate dehydrogenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GAP1_2</name>
        <name evidence="4" type="ORF">HK099_008341</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000090">
        <property type="protein sequence ID" value="KAJ3224542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U518"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046580">
        <property type="term" value="P:negative regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="829"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="3">
        <location>
            <begin position="196"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="873"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="885"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="923" mass="103968" checksum="A9220900A7619C13" modified="2024-05-29" version="1">MQQRQSVGIERGSTTNTNRFKPSHVAKAAFFAAQNGLPLGSAVPSSPGGIGDRRYSVAALWSMAAENDLEVDDDLTKAQRRLRELKAKISGQSKKNFLLERDVRYLDSRIALLIQNRMALDEQQEVAAHLEEHETTDSSVGGLDDRKRQLYGNLFYLLQAEPRHIATLARLVSLGEIDTLLQTVMFTIYGNQYESREEYLLLSMFQNVLAAQFEMTTEFGSLLRANTPVSRMMTTYTRRGPGQTYLKDVLSERINNLLEHVDLDLEINPLKVYEQMIVEIELETGQPSNLPRGLTLDEAQENPDVQAIIKPRLSTLEDIANSFLTTIIESLDKVPYGIRWICKQIKSLTKRKYPDASDFNIGSLIGGFFMLRFVNPAIVTPHAYMLVDKNPSKHPGRTLTLVVKMLQNLANKPSYSKEKYMMALNGFVEANKARINKFFTDLCEVSDFYEALEMEQYIALSKKEISLNISLNEMFNTQSLLLQHSDILCPEMNHHLRICLNDLGQCPAQLPRSENKSVVLPLFSRWETPIIDPLNNSDSQLTQGDILYMDTKSIFVQVLRTIPALVNKNLSLHKVAEVAATSKDQGLVKKGLKVRDMLSQLEELGILDSKDGHKLMVEEVLQELVHLGNLRDTVNRESKSLDLVYKTIIDHNNYLRSQLESYKAYLQNVRVQAGASGTSKTNQKTSKTVAPLGPFKFSHSQLEKEGIIVESNVPEVRRANIYFNMLSPVPGTYIITLHYKGREKAILEMDLKLDDLLEKQQLGVNTLDLEYVHLSVQAEIITELLGVLIPAYCSIHALERSNIDELKHWVAYWSLFSCVSLLDFGKRPLLKLLPFYFAIKLILCAFLAFPQLKGGMRIHLTFIKPLLIKKPPPPSAEGASKVGDKAGASKPKSAGSSEKTGIEKMKSKTKSISAFTYIPLNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U561</accession>
    <name>A0AAD5U561_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAM domain and HD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SAMHD1</name>
        <name evidence="3" type="ORF">HK099_007981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000083">
        <property type="protein sequence ID" value="KAJ3224732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U561"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008832">
        <property type="term" value="F:dGTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050135">
        <property type="entry name" value="dGTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373">
        <property type="entry name" value="DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373:SF4">
        <property type="entry name" value="DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="2">
        <location>
            <begin position="36"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="535" mass="61577" checksum="ADAE4AB07F8EDC3F" modified="2024-05-29" version="1">MENKKVINDPVHGFIELNDVCVSVVDTPQFQVYPGASHNRFEHSIGVSHLANELLKNFKSEQKNLHISEDEEKCVRLAGLCHDLGHGPFSHIFDGEFMRRARPNSNWTHEDGSQMLLDYLVDSNGINDITTPDLKLIKDLIKGDDRSKYSENRFIFDIVANKRTGIDVDKFDYFNRDCINVGIKSNYDSSRLMKFSRVIDDEICFNKNDAFNIHQLFQTRYSLFKNVYTHKTAKAVEYMIVDILLEADEYLQISSSIDDPSQYSVLTDGIIQEIQRSKAPELLKSRKLIEKLNKRELYKWVKFFSLLFIVYSSRYVDKTLVSPVFRDFISQEMFTLDKIIACDESKTLKPNDIIIDWMDLNMGQGKSDPVDNVKFFSKYNLNHSFHIRKDDETLFLSKQNSELTVRIFTRTPEKSVAVQQSFRKRLQDISIEITGRGGAGLIVEQEVVDLRNRLNHSIYSDDYCDTVEDNLTLKSNIDKFKTPPGSEKVGLGFVTSTTPTNRGIFNTGGLTPSIGDTLPNNWESKSPQKKRMRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5P1</accession>
    <name>A0AAD5U5P1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="3 9">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ZWF1</name>
        <name evidence="12" type="ORF">HK099_006968</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="3 9"/>
    <dbReference type="EMBL" id="JADGJW010000064">
        <property type="protein sequence ID" value="KAJ3225323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5P1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000111">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="6 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="10">
        <location>
            <begin position="22"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="201"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3225323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="493" mass="56319" checksum="3EC8AF127873F856" modified="2024-05-29" version="1">MNTDIVFEMTSHSTEKENTAIIILGASGDLAFKKTYPALFGLFKNDFLPKSCQIIGYARSEIKLDEFKKRITSKIKVSDEDKAVLERFLEICTYCSGSYDKKESFQNLDKFVTNLEGEDDRKKNRIFYMALPPTVFISASEGLKENVYSKKGDNRLIVEKPFGKDFDSSRVLSRALSKHWKEDEIYRIDHYLGKEMVKNLMMLRFGNVIFGAVWNRYYISNVQITFKEVIGTEGRGGYFNEFGIIRDIMQNHLFQILSIVAMGRPVTLDAEDVRNEKVKVLRSIKPLSIDDVLLGQYTRSADGKNKGYKDDEGVPQDSYTATFAAAVFNIANERWDGVPFILKCGKALDEAKAEDVPGSIYPGLARNELVIRIQPKEAVYMKVMNKEPGLSNAAVISELDLSYTDRYSLSRIPDAYESLILDVLKGEKSNFVRDDELDAAWKIFTPVLHQIEKEKIKPELYEFGSRGPASLSRWIENHGYKRTHGYQWKSTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5R0</accession>
    <name>A0AAD5U5R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5R0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042054005" evidence="1">
        <location>
            <begin position="19"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="158" mass="18274" checksum="B50F870E98DF5243" modified="2024-05-29" version="1">MYMSLFALFMVLVLYVRMREIYSSLVKQEELDLLNSNFQKAKDELKLSKNLSLEKKEDVQAKTFSYCVKAKLEMQMYQNIKKVIQKKNAHEIVNNASTEKANNSSKKNENESNFSSVQSSLLRFGNSNFSDSKVKVIENLDVKWEIDEKLASVVEEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U635</accession>
    <name>A0AAD5U635_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">UCHL3</name>
        <name evidence="10" type="ORF">HK099_008549</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000095">
        <property type="protein sequence ID" value="KAJ3224377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U635"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="111" mass="12372" checksum="1719DB70C701DF3D" modified="2024-05-29" version="1" fragment="single">LLHAILNGLDESDIDNGNRPLLKIFNKTRHFSADERAKFLESEEASELANLHFHSSIEGQSTVPESNADVDLHFVTFVEVEGQLYELDGRKPFPINHGACINLLEDSVNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6H6</accession>
    <name>A0AAD5U6H6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6H6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="434"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="554"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="730" mass="82638" checksum="F1E840A1293B8F12" modified="2024-05-29" version="1">MTVVLNNLNKPKKINQLKENIEYFRDQVAASFETLKITGMITTILQAELKTQQEEEDNSRSLKNDDKNNMNYRNLLVKRGSKDENADGAGDFRSLISMINSHQNLSQIEEYNKKQGSQFFLRSTEGLTNKESRLALSKRRFFGAEFLKNEGEEVTLKISGSPRLPISTLDTSFNTKFDNNQKTRKNLVSITVEIPADTPIKEHCHFADSSNSKCNFSQNERQNPFMENSFLLASQHIGTNMASLTGSQSHLISSLIEASSNNEESVSKLSDAPFQKVCVIDTQQNCDSSPDLKFRLKEGPTGEPGVINSANKFISEALRVDFCNQKYFSDREDKAHQEHNFTEIPVSFFVPSNNMPLTKFLNEEVVESHDKKINISGFLAELQCSGENSSTPQTTVIDQLLHSEKDTYEKNEIPKIPSINTISESKEKTQLNNRVKDGFGNNTSYSENLEEASPAAMHNQDTKSDHVSNNLDEEGDVMNVEEEKKFQDSEKAYQNWLMEQQNSQTAASSEYHQSVQQKFDEHNIIIARNNNSLVLSNTIIKGGNKHNGSERNSIMDIEEQKNKKKLKMSKKEKKNKIKLQKEKILQNLSLISKNDTEINILVSSGMIPKNLKINLITETLPILDKTLKNYKDELGEKNLFLTKIEKKIKYLLIQSKSFETAEFIENNDFKFGGGFKPNIGSLWALYNSTTGNKKGIVKSSVLDIGESDFKDKIDDNTLLRLEEGRIGSCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6H8</accession>
    <name>A0AAD5U6H8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Ca(2+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PMR1</name>
        <name evidence="15" type="ORF">HK099_005343</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6H8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000008">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="747"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="820"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="861"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="14">
        <location>
            <begin position="20"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3226238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1157" mass="129167" checksum="018657C7A10AB8F9" modified="2024-05-29" version="1">MQSTRWTEYKHDAAHSATAHFATISKTELFSVMKTDANGLSSPESIYRRHIVGLNELRVESTETFIQKFIEQFKNPLILLLFGSAALSILLGEIEDAVSITLAILIVISVAFVQEYRSEQSLQALNKLVPHYCHVYRDGQLCTLLANELIPGDVVRFSSGDRVPADVRLISSIDLEIDESSLTGENRPCKKHSEDLDINPEDLPLAERRNIAFMGTLVRGGNGVGVVVGTGKHTEFGAIFIMMKEVEVRRTPLQEKMDLLAKQLSMISITAIVFIIFIGLIQKRQWLEMLTIGVSLAVAAIPEGLPIVVTVTLALGVLRMAKRNAIVKKLPSVEGLGNVNIICVDKTGTLTTNKMAATKIYTLSHQAVISLDDIENAVTRQYGSSESLQEGFAQLTTSPSVRMLLKIGNLCNNAHINEDGRIGQSTEVALLELLQRMSLPDERPNYTKVSEIPFSGEKKFMSIECQQKLPSFLPESPTNHPNLFYVKGAMEVVLQKCKRIYINEFDQQRTLDKETLNMVVETAERVAASEGGLRLIFMGVGQTMDDLALVGFVALSDPPRKGVAEAIRRLSIGKVKVVMITGDSESTAISIGERLGIYDASMLERTVLDMDNLTEDSNTTSPLKTSNSLLTKTRNPQVLSGPDLESLSRRELEAIIPQVTIFYRTTPKHKMTIVKAFQNLGNVVAMTGDGVNDAPALRLSDIGISMGKSGTDVSKEAADMILVDDDFSTVLYSIEEGKSIFSNIQNFLRFQLSTSIAALTIIALATFLHLQNPLNAMQILWINILCDGPVAQSLGVEEVDPDVMKRPPRPKNDHVVTKPLIQRVLLSAFMIVCGTMAVYINESSNENDSVRRRTTMINEEINIFVSLSLIDLMKLTFLSSSVLWVDEIRKYRNVENEKYSKYNIQEPIVVNSRGEGKIGHDNKKYFGGVNEDREYLEIWRISDFTELKFSPNILIVVNSTIQVGNLFQYFKRSNINAEVFSYHSKMQEPDLSWLSTHNSTGFRIMISTTALCYGIDYPNVASVIKIGERVKKNVLLFNCKSVWEEEKKFYSLELKKVEEHGGFTANLSLYQLNQVYNYDLVVFGDVMEIFENGSFEPLTVVDEKNNFCYAGNSYVWHKTGLFESDWELKRSIDSVIVASYIPSSLLKVKQNITKSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6R5</accession>
    <name>A0AAD5U6R5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6R5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="25365" checksum="CB0D3655EFF5E22A" modified="2024-05-29" version="1">MSTYRFCKIQILNRQSTQRYVIDGIKYTYFTSSIIMMLYLIFEFVSANITSYPIELLKIQSQIFSVSFFLVAACAMVTDFILSCVMIKTVITSLDESNSDGVEKRIKFKLAFLLVISIGLEIFSGILFIKEGQVVSIKFLATMPTYIHLILTSMLLEILSTSNEIVKKAQRNRISKKSNLTENEKFPAKSTPSSFLSVNYNRTGENKTSSLIPEVIMIESQNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6U9</accession>
    <name>A0AAD5U6U9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFAP97 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000190">
        <property type="protein sequence ID" value="KAJ3222132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6U9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038791">
        <property type="entry name" value="Cfap97/Hemingway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029488">
        <property type="entry name" value="Hmw/CFAP97"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23035">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23035:SF2">
        <property type="entry name" value="KIAA1430 HOMOLOGUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13879">
        <property type="entry name" value="Hmw_CFAP97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="650"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="652"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="691" mass="80258" checksum="DD80108521B15843" modified="2024-05-29" version="1">MDSFYDNNEEVFPLTENGNEQLGFLENNEQTINGDNSELVCNIDNMEENEVYNNVGENPSSDFLIPQDSRGFEKVITCDDENENNEEKKIFKLETEDDTKEETSANSDECKEQNSVEDSTIETFTVLDEIEQNTEKHSSVCEQSHKFKVTEESDHNADTEKETESNVSTVVEKNDEFDAKIFDGTESEGCPYTDLEREQFLKELEETLSSDYAKNILNKAARKITDPYPYRHYLSYDAVTSKYLAYKWKNAEKIKFHDRLSHIKPAVDNKPPPNRRHVHTKLKLHFSNQVRQKDIENSNKKLYERIRKIVKTDTQNSHLDKVFNQKNHLFAFAGEKRRIKEKLDSENDRLLIKLEEKKSAYENRKFLNERLTTVNYLKNISGYPASFINEYERLTILKKNSKNFNKLPIRQNSTSVLDNCNVHFNQRGQEAAKIDYSKLLLKKELDLPTLLPKIKTADVKKTDKYSGATIQRENSPIENVRTLEVQATVDKFDSEIEKSCDDDGVCNNAFYESKRNENDEESQFVIDTKEIDQNFSQNGLNENHIHKKVCSITEFQGVGDLNQENAEEPLILDNSQLNEILKEKGMMLTEKNGHNVEGEEIDAPINSEEIHYSNKISTEEQDCSELQKEDESENQLTLDLEKEIEFEHEDNAFEEYIEEERDDNNASQVNEVSNKTDEEAETNFDHDDFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U703</accession>
    <name>A0AAD5U703_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000030">
        <property type="protein sequence ID" value="KAJ3226715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U703"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="15"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="137" mass="15630" checksum="C1F1C090FF1D144D" modified="2024-05-29" version="1">MLIDQTSPSTAESFKKFAQTDSPKHDYPTEVVSVSYGKALIAKKDVLPGTVLEKFIGPDVDYEKLSDFDKCYALNYFSDIKNDWVWLLAENNARFANHSCNPNSIINKNQEIVAKKFIKSGEEITFIYNIGEDSDYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U756</accession>
    <name>A0AAD5U756_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Letm1 RBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002245</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000173">
        <property type="protein sequence ID" value="KAJ3222491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U756"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="9">
        <location>
            <begin position="190"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="364" mass="42492" checksum="D7E0418A824D6ECC" modified="2024-05-29" version="1">MNISIKFKRNFNPSKLNNYTLKNEGLLFYTGVKQKRFFSKSICLNSQFDKKLQRHSENAENGIKSNTGVSKIVTYKDFLQNPSLNVLSDLSKHTFHKMKSQFKIYFEGAKLLRIEAAQAAKIAQSKKFEDFTRKDFLLVQRSKDDVKKLIPFFFLLLLLPEAIPFVIIYNPGFIPSTCWSKEQILDRRANNDKRRLELGKLILESFEIGTVVKVANISPKQFLDSDFYQRLIISQRQYFDVNKFDTNQLAFFSKFMGLYHKGPRYFTKRRLNKILEFIRNDDKFILKEGGVEKLELCEIQDACEKRGIPITSRPAGHYTKDLKDWVTVSLLKQDSIEHHGTEDVYFVPSGFILMWNSIKVGLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7L8</accession>
    <name>A0AAD5U7L8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Dynactin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_001124</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="13">Subunit of dynactin, a multiprotein complex part of a tripartite complex with dynein and a adapter, such as BICDL1, BICD2 or HOOK3. The dynactin complex is built around ACTR1A/ACTB filament and consists of an actin-related filament composed of a shoulder domain, a pointed end and a barbed end. Its length is defined by its flexible shoulder domain. The soulder is composed of 2 DCTN1 subunits, 4 DCTN2 and 2 DCTN3. The 4 DCNT2 (via N-terminus) bind the ACTR1A filament and act as molecular rulers to determine the length. The pointed end is important for binding dynein-dynactin cargo adapters. Consists of 4 subunits: ACTR10, DCNT4, DCTN5 and DCTN6. The barbed end is composed of a CAPZA1:CAPZB heterodimers, which binds ACTR1A/ACTB filament and dynactin and stabilizes dynactin. Interacts with ATP7B, but not ATP7A, in a copper-dependent manner. Interacts with ANK2; this interaction is required for localization at costameres. Interacts with N4BP2L1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Stress fiber</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dynactin subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7L8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001725">
        <property type="term" value="C:stress fiber"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008603">
        <property type="entry name" value="DCTN4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13034">
        <property type="entry name" value="DYNACTIN P62 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13034:SF2">
        <property type="entry name" value="DYNACTIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05502">
        <property type="entry name" value="Dynactin_p62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042152124" description="Dynactin subunit 4" evidence="14">
        <location>
            <begin position="29"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3227617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="21635" checksum="405CA71522CD1532" modified="2024-05-29" version="1">MPKLCSGENCVLLLPKLLFEVTTASVKAEKNRCARNCFECPIFLNTLSVIFSVDPEKEPSPPTWADRASSTPNSLHSPGLSAGSVHYLLWGLCRWDSLEINLKFDRPTGIASNQLQKTEDDRDDVKEFENLRDHFEQIFRSNATGAHSSSLRNSDLNISSSLLASIPSLASLSSYSLLKIIKLLTKSNIGFFTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Z7</accession>
    <name>A0AAD5U7Z7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">OXR1_2</name>
        <name evidence="7" type="ORF">HK099_008296</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Z7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="6">
        <location>
            <begin position="305"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="540" mass="61769" checksum="A35EFC63459B28BA" modified="2024-05-29" version="1">MNLHPEQHLKKTAKSKRFENSNHEYSNNKDIKLENSYIFDGILNFNPSKEIPVSSSVELPTQEFYEKKTDLSKSKSPQLGFFSRLLNQLNFSDESESESEHEFENQYEHIDRNEVDHVMDSIKDTNPSKKDEKIEGTKPLYDSVKSLEKSEEHPSQDNISVNSNSLSYQENFPDSLSDFFWDLFGLKHSAIKNLNKVNNDTPVNTPISNNLFEINDDQCWDSIKKKRKIIKFQGYENENKKSTSFFSPEKENSTYVDAYLKTENGADFCENVSKLEKLEFLRQQTSSGKDDRQGKVLEENSLQEGIMFQNLAQDLLPNLPPLYQEALTWNLVYSIEKHGVSLKTLYSRCFDAGPCLLLIKDDKGNTFGAFSNQEFAVNVGYFGNGLCFLWKWDVKKKKIEVFKATGANEYLVLCETHFIAFGGGEGKFGLWIDEDLLNGYSGHCQTFNNPDLSLVDIDDEDMKEIEGEKNSTDVKSIEIDGSVTNSKVKNNIEDELVDVTTTSHGRLNVDEQITARNGRKTSVDVGRFEIAQLEIWNFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8C8</accession>
    <name>A0AAD5U8C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PCK1_1</name>
        <name evidence="11" type="ORF">HK099_003508</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8C8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.8.10:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="585" mass="65254" checksum="97EECF2E4319C0E1" modified="2024-05-29" version="1">MNLKLLNQTIKNHNFFFLKSITRSSFLVNSYCNQFKSLTTEKKNSKFLQSITKSTGLNLENVKVARNPNPAVCYEDAIKYEKGSFITSTGALSALSGVKTGRSPTDKRIVDEKNHTDNIWWGPVNTKLSEESFVLNKQRAVDFLQTREKLYVVDAFAGYDPKYRIKIRVITSRAYHALFMWNMLIRPTAQEQKDFGEPDFTIYNAGQFPANKYTKGLTSPTSVSLSFDKKEMIILGTEYAGEMKKGVFTVMHYLMPLKGVLSLHTSANAATTGNKDVSLFFGLSGTGKTTLSADSARSLIGDDEHCWSDSGIFNIEGGCYAKAIDLSQENEPEIFGAIKFGSILENIVLNKETRLVDFSNKGITENTRVSYPIEFISNSTIPCLGGHPTNIILLTCDAFGVLPPVSKLTTEQAMYHFISGYTAKIAGTEEGVKEPQATFSACFGQPFLVWHPMKYAEMLTEKMKKHKTNVWLINTGWNGGPFGILILLFFKLIVAIIDGIHSGELNSSSKFENFPVFNLKIPSSIKNVPKEILNPELSYKGHKESSFNDGVKSLATLFKNNFKNFRTGAKDIKEIDYLIKHGGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U988</accession>
    <name>A0AAD5U988_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_007980</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000083">
        <property type="protein sequence ID" value="KAJ3224731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U988"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000009">
        <property type="entry name" value="Mitochondrial 2-oxoglutarate/malate carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="15"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="104"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="202"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="302" mass="32530" checksum="7C9BBA03AB237A2F" modified="2024-05-29" version="1">MSSNSNNKSITAKAKPFIFGGISGMVATTCIQPIDMIKVRIQLSQTGVNPIILTKNLIQQEGFQSLYKGLSAGLLRQATYTTARMGLFNTFLNSSKEYNNGKPVSFTQRAISGLAAGGLGAMIGTPADLALIRMQSDGLLPVAKRQNYKSVFHALSKITKSEGVLALWNGCGPTVARAMALNLGMLSTYAESKSHLEKKFGVNPYSKLGASAVAGFFASFFSLPFDFVKTRLQKSSESSLGSFQCAREILKNEGALAFYKGFGTFYFRIAPHAMVTLLVAEFLTGLDQKQQVVNVNTVKAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA88</accession>
    <name>A0AAD5UA88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA88"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="759" mass="85686" checksum="5E8DD46D83E9C1E8" modified="2024-05-29" version="1">MRVNELALNVFPNNNISNQKGDIQNIPVEEEDDEFEDAKVELEPVATNKGADPISSQQSTSEDENDNCKFKLTKKELKQVISDSTEKQLLIDIIQVEVALDLFLDSKFNEAENILKKSYGKSLYFTLGYGVIRMLKAVMTFDPEDIRIALEALKLAQELGNILRKAEGIDAPPNHTPSSSQKKWTLSGLLGLQGNKEGQYLLNLTQVQRHSELVAAEAQVLRATLSMITQTNLVAFVKEGLAIRSSYNTIKVCLKFLERTYEEDGGLEAFEKYGLDEHFISGVTGIAGMFNLTLSLLPAKALKLFELIGFSGDREFALSRLEISARWPLDSNKSRLVPNDFKPCFPMPAKKSECGGLRKPMSDLILLAYHLVLSSMICLPDCNLPLAELQLEEILSKRSNSFIFLALKARMLQTKGLPAESEAQYLRVMNIQKDWTQLIHMCLWDIGNLRAIQGKWKEASDAYSTLFKESKWSVAIYRYLEAICLYSIGNSENNEKVATMLKELPKLTKKIAGKSLPMEKFVCRKARKFFKQNQRLLIPGLEIYYFLGGLEAMDTPNLLRTIALVDKEIKNLESQESASDGKLPYPTFYDDLCLTRFVKAVLERERVFPKSKTLIGIKEQVLQGKQFNSCLTGESLPEKFINLEQKPTDSQISTLKYSLKNFEAVINQSSEVELDHWMLAFSRYEVGSLYMRCGIYEKAKKEFEAALNGGKGEDDEVEVGKANDGVKSSMESNLNIKCHNALIKLNCLELMEKRLDSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAC9</accession>
    <name>A0AAD5UAC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002417</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAC9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042170190" description="Tyrosinase copper-binding domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="492" mass="54103" checksum="1DE4D4E73213B6EF" modified="2024-05-29" version="1">MVNFRVRLISFLVIGLTCSIRREVRELMNSDRSGLNGEGQAFVDAVNCLMDSGRWSRLKNVHTKNIAAAHNNAAFLPWHRLYLLALESEMRDCTGQSISVPYWDGTLDSQNPEGSPVFRFFGSNGNNNGPFRANHFSRSFNGGSLPGPEAVQRIESGNNNYDAAREAMEGQYHPYVHSFVGGNMANLYESSGDPLFYLHHAFVDKQWAAWQQNHPSIANDYNGPGPFGGQASRNDVLDMDGVIPDRTVSQMFSISQLGYSYSAGAGPITGGPDPTSVAETSTTSTTSSSVSISSTSTVAVSSTASAALNSTTLLPNSTTTATVLAVSTKIIKPLSSALPTTPNSAALPNVKNVVSNLSKFIKRSFFGMEAELDHVHFQFKKRGAYHGSLDNTVTPACEDRDDEYNLRHVSPLSEHVIKKNGLNETYIRENEKTMNDLVDFLNKERGYLSNAALLYHEGYGKDLLDNYGSITEEQSLKNKKYVQEKINKFYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBC1</accession>
    <name>A0AAD5UBC1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001672</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBC1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="335"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="418" mass="45662" checksum="B531E78BC9D88811" modified="2024-05-29" version="1">MSSSSGNGCLSLSGSRFCPQYSEFNVATAFATPKLNPTIEDFDNYINNTFSTNKFFSNSVKTFLNCADSNYTSENLRYLVSVNCALIVDTSASCNPTIKPLPLCKSVMSLFFTKFTQDLAAPNDPTSINPNVCKFDGSNSRNLLQTYSILFNNSALSDIACTPGTSIELLQCGFSNVSDATEYCKINSNELCCKSTVFGGNISDVQLLLPIPLASNQTTSTASFQPSTNTTGGTNSTEIISPIFNSSPVSSSPVVLGYEPIIILGVTLVTFVVLFSFGLCCCLLLKRKKAKYQRRILKFGSNLPVLEKSSLSGFQRLSLPANNDNNDDNFVGARNITETLQAHYDYVPNLSDEITLYVGDPVLIKQRFDDGWCLGYNMTTKEEGSFPIACVGPYNNLKKENYDSAQFSNRTSSLIFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBP7</accession>
    <name>A0AAD5UBP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBP7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="172" mass="20373" checksum="935A42AD76CAD19D" modified="2024-05-29" version="1">MDKLISLRKLKTKSETLAQLMHEYKNNSVQLEKKQNFLKDYQREVSIRLQEKEDLKLRLQSVFEELKSLEKLEEDLNLKNYLKEEEETKMMLEKKSEVLIKEVNDIREEHGLIKLSSLNEQLTESCNKLLQDYREKRKSEFDFDDNYKVGGGTSSQKTSSKSSPHLKKKKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC49</accession>
    <name>A0AAD5UC49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC49"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16988">
        <property type="entry name" value="ANTH_N_YAP180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.150">
        <property type="entry name" value="ANTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014712">
        <property type="entry name" value="ANTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045192">
        <property type="entry name" value="AP180-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951">
        <property type="entry name" value="CLATHRIN ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951:SF5">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="2">
        <location>
            <begin position="10"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="673"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="693"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="744" mass="83538" checksum="689CEED40497DC71" modified="2024-05-29" version="1">MSGIKEKVRIAKHYFNDIERYILKSTTGKIKPLKPKHVQALTSITWQNDVSIDVVFELIGKRFREGHWVCVFKSLILIHILIRDGHTDKILSFLSANPQFLKLNGYRDTSSNFVGNIQAKNIRAYASYLEEKVKGYNLIRDDFVRRQPEYIAKFRSMPYENGLLEQVKSLQSQISALLNCSFYLDEIDNLVTLQSFRLLIGDAMALFHLLNEGVIKILSCYFEMERDYASKALEIYKVFSKQTTKTVEMFEIARKLRSSLGVEVPVFKHAPVSLGSALEEYLNSPDFEAQRLAYKLKKQQKEKPAVKETKTSLTAAPSKIEKTPSKIETSPPKKDIDQIDFFSSLDEHFNSYNSPTNQANFNNFANNQVSPFISGNPFVQNSPQQQYMMQQQLPLVNQQNQANPFQHNQNNFPQQNNNFTVENVFGANNVLSPFSKSIVSNNTGSTTSNFSGNQSVRQTIAVSDLTGNTTLDPFALNSNSNFLLQQQHMNMQQSSPLLQKNNTINAGFNTINDNTRNFSHQRSHTVSSSVQQNGSLDQHYRNSSQPNANLSPQQYNVAPIPQFPMSPSNRFSQPVVHNSPFQQPAVFQPNNNFMTSNHQNVQQSKMNSNDGLGIRSSPLDAFNSLNPFGSTTVPVTSGMSLNAIANYNQYSHQSQPQQYSTFNKTDFNNNDLTMGGLGQGNNNPFLLNQNTGSSSSVPFLSSQVTGSSSSNNPFSTGMRNTIPQQQQQTQQFLGNNALGQVTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRV8</accession>
    <name>A0AAD5XRV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001958">
        <property type="protein sequence ID" value="KAJ3200167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRV8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3200167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="179" mass="19386" checksum="900F8B0AAF5D87B5" modified="2024-05-29" version="1" fragment="single">YDLSTSTYSPDGRLFQVEYANKAVDANGVVLAVEKLIQSKLLTAGSNKRIGHVDLHAGIVGAGLSADARHIIKRGREESSNYKNTYKTAIPGKILAERLGGYIQAYTLYSSVRPFGLSTILGCVDRNGPTLFMIEPSGVYYGYNGCASGKGKQVAKAELEKLKFTELTCREAVNEAARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRW5</accession>
    <name>A0AAD5XRW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rad21/Rec8-like protein C-terminal eukaryotic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001927">
        <property type="protein sequence ID" value="KAJ3200323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="entry name" value="Structural maintenance of chromosome 1. Chain E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006909">
        <property type="entry name" value="Rad21/Rec8_C_eu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04824">
        <property type="entry name" value="Rad21_Rec8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein C-terminal eukaryotic" evidence="2">
        <location>
            <begin position="195"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3200323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="239" mass="27566" checksum="E9F2358B373311A3" modified="2024-05-29" version="1" fragment="single">MSLEFVQCSSNEKKNTLKRYRGGELKNRQNFDANSKLKDYSEGIVNVESSRFQQRFEEESTNEIEMMREGKEKRRRSNFSPATLGNQSSISGSIAEDFSTPGSRRISGFEFNSLNKSNDTGERAVDRGDLFDPLTENFFDDHRGSKNESMGGGILFEDEENSYINKESQRTFEFERDIDSFQNYLKEIMRAANTNFIFLNDLIPEKNVSQAARMFYFVLTLTSRGDFKAEQIKPFGDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSL5</accession>
    <name>A0AAD5XSL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rhizopuspepsin</fullName>
            <ecNumber evidence="3">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PEP2_3</name>
        <name evidence="13" type="ORF">HK099_000919</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010001231">
        <property type="protein sequence ID" value="KAJ3205124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSL5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="332"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="12">
        <location>
            <begin position="1"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="15"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="216"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3205124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="507" mass="56047" checksum="B5935B6DEBF9A1F5" modified="2024-05-29" version="1">MDTGSSNLWITSSKCGTRCNTPNKYYGSLSSTHISTTKTFDIQYGKGSVSGYISQDTLKINGIELPFTYFGEAHVTADVSKVFDGIFGLAYQSLASNQITPPFNAMFANGQIEQNLFGVWLGEVTEGGGGEITFGGIDEKHFVGELTYAPVVKQAWWTVSIEAFKIGNQLLSITGRTGAIDTGTSLIVVPKSDFDLINFQLGGTLDTTRGLYKFDCDFVSELPTVSLKFGGRYFDLTPQEYVWFQGQSCISPFTSGGVGENSMWIVGDTFLRSYYTVYDFALDRVGFANSTRFAAPPEEKPDLTSQGNDNGNVGNNVAVATKTELNVEAKSLSAGGIFGIVISIVLILGLLIFLFLRKKKEVNFKKKVSSSSTIKNNINKMKDFRTTSSKKKKFSNLEKLEEGKIISSTRRINSPVSPTKLTRRRSSIKKADIGEFLQPIGKIVDDDKILDLIDKDIFKNGFNEIVVSEEQRSSIIKVPDLSVQRKKMEQDLKNQLDLPTTEFRNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSQ8</accession>
    <name>A0AAD5XSQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Autophagy protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ATG5</name>
        <name evidence="6" type="ORF">HK099_000404</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001096">
        <property type="protein sequence ID" value="KAJ3206833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSQ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044233">
        <property type="term" value="C:mitochondria-associated endoplasmic reticulum membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.190">
        <property type="entry name" value="Autophagy protein Apg5, helix rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007239">
        <property type="entry name" value="Atg5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048940">
        <property type="entry name" value="ATG5_HBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042526">
        <property type="entry name" value="Atg5_HR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042527">
        <property type="entry name" value="Atg5_UblA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040:SF2">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20637">
        <property type="entry name" value="ATG5_HBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Autophagy protein ATG5 alpha-helical bundle region" evidence="5">
        <location>
            <begin position="55"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3206833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="156" mass="18654" checksum="FCA7B0DB04945FEF" modified="2024-05-29" version="1" fragment="single">HYPVGLLYDQLFNKFSENEKYCQGSPWVINVHFQNFPSDKIIFFNLNPLSKLDPIQEYYYNMIKQADFLNSGSVKNVMSLSKEDQTDLWNGLFSHDYDKFRTSKKKLLVEKEETKNIPIKFYLQDFKKLKLDEFHLVDYKLYQDPVSPLDENGKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUK8</accession>
    <name>A0AAD5XUK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000493">
        <property type="protein sequence ID" value="KAJ3216166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUK8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="175" mass="20451" checksum="328CE078A1C71B9C" modified="2024-05-29" version="1">MSFLNKFDTCVCENQQIFIECYDKKPIFLKNDSCNLHTLFKVGEELEFINSNFTDSLGLNCRKIKTTEKVFHTAGGNIAFDNDILQLYNVLPFYYSDAKSDYLKNWPWYVWLVVALSCLMILTVFIYILIWLIRRSHKFWEVGSVTESIPQKAPIVRNLKQVRVINNHSNAGPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVA6</accession>
    <name>A0AAD5XVA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial 37S ribosomal protein rsm10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RSM10</name>
        <name evidence="5" type="ORF">HK099_004924</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000364">
        <property type="protein sequence ID" value="KAJ3218818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVA6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="4">
        <location>
            <begin position="60"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3218818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="227" mass="27018" checksum="AC2F5553DF92D054" modified="2024-05-29" version="1">MTTRNHIINYIKKHFHTTSKINREQPYSWSNFNLNNNEQIFKIKKLDPLSVKEDSKLCLNLEIRSFLPDTLDFFTYFARYSATAMSIPTLPVIHLETELKKWWVIKGPFVHAKSKEVFERKVHRRLIQVFDTDHVLMKEYINYINENLPSGTNLFVEKFLYEDLNISHQLKSKLNLKEKQQAEELEGLDASLVKVAEKEKPFDMLVRERSQFFLDHLMKQVNAEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVY6</accession>
    <name>A0AAD5XVY6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein fam72a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FAM72A_4</name>
        <name evidence="2" type="ORF">HK099_003906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000263">
        <property type="protein sequence ID" value="KAJ3220921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVY6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026768">
        <property type="entry name" value="YPEH2ZP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31841">
        <property type="entry name" value="PROTEIN FAM72A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31841:SF1">
        <property type="entry name" value="PROTEIN FAM72A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14976">
        <property type="entry name" value="YPEH2ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="181" mass="20717" checksum="E670ADFDD34837A4" modified="2024-05-29" version="1">MTFNNQRLGNNNNDTNSTAISITPYPHMQDFVLYLQDIEKLSQEIEKLKKFKRYLNKSVFNLNCKNCLLKISERGMKSYLLFDSSMKFSASIDQVYNVSTINEYENINCDCLIGDLGCTGCGTVVGYEIRQPCLNCVMSNHNGHCICFDGECIISSEIENLNWGKIYFSPDNFHSNERLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWF5</accession>
    <name>A0AAD5XWF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000207">
        <property type="protein sequence ID" value="KAJ3221818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWF5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10537">
        <property type="entry name" value="SET_SETD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040415">
        <property type="entry name" value="SETD9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33524">
        <property type="entry name" value="C5ORF35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33524:SF2">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="248" mass="28827" checksum="470DB9A73678870E" modified="2024-05-29" version="1">MRNYLNRFSPLQLLKLHISRQIPTSADALKSINSPTLLTSLSELLNEIHEKSFGNLAKNELQINFKLSKKESNIKKAGDGVFITGFRKKNSIVALYPGLIYDQANDPKFIPSLNNQYFLRCFDGIYCDGKYNGLSKLLYTSKYSRINDPLQTIKFGDRSWLKKEELLNFLNCGQFINNANQNFTSNVRYQELNVPPTFPMELRYLIPNLHYRENWIPFEDFTRVICLISTRDLKNEELFSTYNDVVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWJ2</accession>
    <name>A0AAD5XWJ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GDH2</name>
        <name evidence="6" type="ORF">HK099_002790</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000196">
        <property type="protein sequence ID" value="KAJ3222009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWJ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="5">
        <location>
            <begin position="639"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="993" mass="112898" checksum="C07468C45C105966" modified="2024-05-29" version="1">MSEEDYKGNIFAGKQDQLKAVCVYIEEKGFIPKEMVKNEVTWFYQNLGIDDMYFQLEEVGTIANHIMSLYGAKIFAYIRNEKGLDLHLEREGEERAVYIHTSKPGISMVTGTQYEKRIDTKYLDITSKTQAFRLESYRSLGTVSSSLSTQLRCYFIRKCSFVTPDPTPEQAGDIRLVSDKIFLEKASDHTLGIYEKIMRQVLVRTGPVIEKFDMANSNEKRLVIGYKHRGTQSFFSALSDLYHYYDLYSTRKYVEQFSNGVSICSLYLAQVPNSPSPPIEHSIFQVMKEASLIYCLPTTPLQSFFQTGKLSVQEAIYGYVGWIFAQHFLNRLGGEYNALTSIVDQKNNTHVEVLSRIKKRLRSDTFTREYILDIIKLYPDLVKLCYINFAVTHYINPARNDSIAPSLSYQRIQSTPMLSDDELLEQIKKTVTNNHELMIFESYLTFNKHVLKTNFYQPTKVALSFRMDPQFLPSSEYPNELFGMFLVIGNEFRGFHLRFQDIARGGIRIVRSRNKEAYSINLRTLFDENYNLAATQQRKNKDIPEGGSKGTILLDVGQQDRALAAFEKFVDSILDLLIVGQSPGIKEKIIDLYAKPEILFFGPDEGTADMMDWASQHARIRGASFWKAFTTGKSQSIGGIPHDIYGMTTRSVHQFVLGIYRKLHLKEENVTKMQTGGPDGDLGSNEIKISKDKTVGIVDGSGILYDPEGLYRPELVRLATKRLMISHFDVSKLSPKGFRVLVDEVDVRLPSGQVVADGLRFRNEFHLNPVVKADVFVPCGGRPEAVDVSNVNTLINEDGTPKYKYIVEGANLFFTQEARLRMEAAGAIHFKDASANKGGVTSSSLEVLAALSFTDEEFAEHMMVKDGAHPPAFYTEYVKEVHHIIERNAELEFECIWKEADRTGKPKSNLSDLLSYAILQLNAEIQTTTLWDNVELRRIVLTEAFPNLLLEKLGLETLLKRVPENYVKAIFGSYLASRFGNNFSNLFLIILFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWJ7</accession>
    <name>A0AAD5XWJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001830">
        <property type="protein sequence ID" value="KAJ3200814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWJ7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="85" mass="10270" checksum="B6C5A4EB4BEBD135" modified="2024-05-29" version="1" fragment="single">NFQLQLKRLKIKKLKNNFNNFNRNKQTFNQINEEENDIRNSINKKISNTQELESEVNSSIQQIEMLNQRFSSKFKAITEFENKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWP1</accession>
    <name>A0AAD5XWP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YCK1_1</name>
        <name evidence="8" type="ORF">HK099_002144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010001693">
        <property type="protein sequence ID" value="KAJ3201650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWP1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="29"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="434"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="435"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3201650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="489" mass="55908" checksum="A2CAAD66B686B5C7" modified="2024-05-29" version="1" fragment="single">MSRNSPQTHQSPRQSKSSSAFPNIVGNHYRVGKKIGEGSFGVIYEGSSLITHSPCAIKFESRKCDAPQLSNEYRTYKLLAGIPGVPAVHYFGQDGLHNILCIDLLGQNLESMFDLCGRKFSIKTVAMVAKRMLTLIQSVHEKNLIYRDIKPDNFLIGRTPRSNELHYSIDFIANHSPNNPHPTSQVFIVDFGMAKQYRDPNTKVHIPYREKKSLSGTARYMSINTHLGREQSRRDDLESLGHVFMYFLRGSLPWQGLKAATNKQKYEKIGEKKQSTSVRELSDGFPEEFGQYLLYARNLKFDEQPDYDYLRRLFDKVLHKLGQHDDGVFDWMIEMERQLREREKRRKERELQYASRLATSDDSPIKNERFSSYQDQSNFLKPTASNQTLNTSVNGINHSTTVGRDISKATLTPPGSSPYLNNLREKDYISESRLKNSGSPTAQNSHATFQNVPNVNNTSSPRIKEAQQQPIEINNNANNQIIEPKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXF0</accession>
    <name>A0AAD5XXF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000761">
        <property type="protein sequence ID" value="KAJ3212830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXF0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="183" mass="20723" checksum="465183BA4C27C860" modified="2024-05-29" version="1">MGFLKLKSKKNNQDNFFINNTTTSFKVLVSNQVGYDPEFVEPKFNTLDNKGFLSQSRPNVSNATPANRNEETEIVVTGKPMVEEERLLFNNTETATLEPKETLYNLQVQTTNPNIPIRGSSQQPLPEVNKFKKLKNPTLQNLIVNDLHQNHTLSPPTVTTPLTATIDEIANPRDSTFFKNIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXI8</accession>
    <name>A0AAD5XXI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CLA4_3</name>
        <name evidence="17" type="ORF">HK099_007510</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000732">
        <property type="protein sequence ID" value="KAJ3213227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13279">
        <property type="entry name" value="PH_Cla4_Ste20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000768">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.810.10:FF:000005">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="14">
        <location>
            <begin position="5"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="16">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="354"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="195"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3213227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="624" mass="71430" checksum="7BBFBF900E98C2CB" modified="2024-05-29" version="1">MTATSIIKRNYLYVREEGIRSFLWTKRWILLREQTLTIHRNEHTFQAITLIFLKDIIDVRRTGHKNYSFEIITKEKNFYINCKSDNMLYSWIDEIYHRSPLGISSPTNFSHNVHVDFDIYTGAFTGLPQHWKALLDSSNISKEDMSRNPQAVLDVLEFYTENLTSANGMLHLPDEKIKNYSGNIQNSTSQIMPAVNNRSSSLGRKNLKNKSTPSFLTVDNSLSSSRGRSNSFDSRRPSFDNENIKLDESHYKYFILPDIPPVDYDNEFYNLPPIRPNDASLKNMLDFQKNSILSSQHRPLTANRPLHSLQEKNVLPPPPSNSQNQLKPITRPHKEPRLSVMTDVQLLTKLKNVVSDTDPTLIYTSASVFVAKNTQTNEICAIKQMDIAAQPRKDFIINEIIIMKENQHPNLVNYLDSFVVNKDLWVIMEYMEGGTLTEIIENNTMTESQISFICHESIKGLHHLHTNSIIHRDIKSDNVLLDSSGRVKITDFGYSAKLTIEKSKRKSIIGTPYWMAPEVVKQKEYGPKIDVWSLGIMAIEMIEGEPPYLEEEPLKALYLIATNGTPNLKSPNKLSGIFKNFLGRCLEVDVNKRSSTEELIQHPFLKLAGPSTIISILVKKSLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXN0</accession>
    <name>A0AAD5XXN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Solute carrier 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ST1_1</name>
        <name evidence="7" type="ORF">HK099_000304</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001064">
        <property type="protein sequence ID" value="KAJ3207302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXN0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="441"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3207302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="574" mass="63802" checksum="90FDB7BD6E7D9947" modified="2024-05-29" version="1">MTAVFPVMIYSIFGSSLHLSVGPEAFTSILFGMTITSQTTLGHDAINTASWLTILIGTFCLILSILRAGYLENILTGYLLIGFITGIALLVMVEQLPNLLGLDIKFGNVSLSEKMSLVFSKTAATKNLTLLLVLILVIIMIGVSYAADLNMKGVKILGFFDSSLPSPSVPQFDKKLIEGLIEPAIIIAVTGFIESQSVTRTFGYKKGYFPDHNSELFALGFSNVIGAFLGCYASFGSLPRSRILFNNGGKTTVASFLSAVFVLIITLCLSEILKFLPKTTLAAIVFVAAFNLIEWGKLINICKHKSYGEIWMVLATFIINLLVNIQSAILLSLITGAIYIIKNSTVVDISLKGRIEDSLVVKFSDEDKDSSSRELQLKNRTSIVNSSKMSKNSVAPTVTKELAETTSKNENETVDKEDINGKQIYNKINKKKSYIYVNMDEYPEAEILGNFTICSINVPLLFYNCCKLRVEIERSRKRQARYFQKDTQYTENNTILLDFQNSKAIDGAAVSILKGLIRSYKLNKVKVYFSGLNKMHNRNFKKGGLHKIIDFEKEIFKNITDAVQKFEERNLNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXV6</accession>
    <name>A0AAD5XXV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PRE4</name>
        <name evidence="5" type="ORF">HK099_007587</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non-catalytic component of the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000075">
        <property type="protein sequence ID" value="KAJ3224958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXV6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03760">
        <property type="entry name" value="proteasome_beta_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016295">
        <property type="entry name" value="Proteasome_beta4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF6">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001213">
        <property type="entry name" value="Psome_endopept_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="253" mass="28445" checksum="F6FAE6C740E73C32" modified="2024-05-29" version="1">MFDPFSEEGKDTRNPIRHTQQPVIVSSSVLGVVYKDGVMLASDTLASYGSGLSRFRDIERLKPVGEYTVVGASGDNSDFQYITHTLEGVTTEEYDWDDGHKLGPKNVFEYLHRLMYGRRNKMNPLWNSLVVGGLKKGEKYVFLIGSIKFVRFLGYIDLKGTTYQSEAIATGFGSYLAIPLLRKATENGRYKTLSEQDAKKLLEDCLRVLWYRDATANNKIQVATINEQGVSVSAPYKLDTEWGFAEHIRGYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY46</accession>
    <name>A0AAD5XY46_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mediator complex subunit 15 KIX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007336</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000070">
        <property type="protein sequence ID" value="KAJ3225131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.20">
        <property type="entry name" value="Coactivator CBP, KIX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036529">
        <property type="entry name" value="KIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036546">
        <property type="entry name" value="MED15_KIX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16987">
        <property type="entry name" value="KIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mediator complex subunit 15 KIX" evidence="5">
        <location>
            <begin position="141"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="208"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="604"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="790"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="987"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1033"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1149"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="951"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="267"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="327"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="410"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="604"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="676"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="806"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="847"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="990"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1033"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1071"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1175"/>
            <end position="1189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1337" mass="146444" checksum="939142B4E12E7FAC" modified="2024-05-29" version="1">MFGQSVNANNPNNNLNNIAGANQNQSQAYQQMLSNQQQLQLQQLLQHQGHHSLNHSQQLQVNQLHQQQLQQQRMLLFQHQNQRSQQDNDALQTQQQSHLLQHQQNQLLNINNNQNNQMAPHQSIQFNQQQQLHQNQGPPFLNEQERVSIIHKLIELLRTVIPPQAEERIQYLAQNLELKAFRTAMSREMYLLTIQQQMSSITQRRPELIGNGIPAGGLPPGSPQLDPLNNQAVPGSPHLMPGQSPQLMAGQLRNVQQASQQMQSPLLQHLQNQQQQVQHNQLQNSQQQGHQQMLKEQRMLQQQQMHLQQQQLQQSLLSSSGGNQLKNGNTNSSNIGNTSNNVQPSQNSSNMQQANNPQGQGTSLNPTSPKLKDMKNEAAQSSATSVVATPDSSKNNDNSSPKVKAEPANTPVTFSGFNASDAPVTTSDPTSSTISASGTFSGQQAPTGTPSNTGTTSQAATSFSASEQPSDSLTKAESLSNSVQSFFSNAGLPANSGGSTQSNGDTSVITAAVSGAPEMAPLYRNIQRWIDILHCFGSEKEYDMIKKLQGMKRMMEAQLEGFQLNQGIYYLTPDTVSQLQQNLIRFYQYAEALRVQNQRVSGVQQGMGTSNTNPINTPSGLGSNNSVNSPIPAQAVTSGANQNRSSPAQQPSQMPISSSALLNQSGGGQNLAGNAAPQQTGINPPTPQQAPGSLPPNSIQNQHMINQLGLNMANTGMMGVMGQQNTLINQLSGIQNPGQMMMRPQHQITSAQLAQMNPQQLQQLQQIQMQQHAALQQQQLQQAHLQRSPALAAAQLRGGQQGQMGNNNPGVRQNSQMSPQLAAGQLPGNRMNSIGASPVMSAQVMPQQLGQSQLQQKNSTSPPKQSPRVTPGQINQSPSMSAAMLPNTVVGQMNLNAQHQFSGMNPQMIQQLRMQQQQMLQQSMARGVGNMPAGTMGMSGIMGSQYMNLNVEQQNALKRQMEQQMIQNNNQNNNQNNQQNPHLSNLQQQHSQMQNMMGQGLTSPHLQPGNLSQGNLSHGHQQQNNMFMNQQEQQANLLQQQQQHQQNLQQQQLSGRSLQHQIPTSQQQVGQIPQQESIPQQQQTPANSNTQANANAINKNANAFGNGLYTSSSNLEQTPAPVSNVSAAPGNEMTNEENIDSLFDFNYESPPPTTAVDEPVDTSLTNTTTVGGKRSKPDDFDSEDASEKKLKAGESINTSVLDEFNDLFTSPVNSNDTSTFNFATEQELKNLQSKYNFQYTINSEESFSGGGDLFSSTSVIAVCNFKNISLIFKFNSKLDNDGAATTNFVDCKELDGNGTLKVLNIKEELEKIGVNNSNNKEWKLSEIFERLNSILLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ10</accession>
    <name>A0AAD5XZ10_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_003748</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000025">
        <property type="protein sequence ID" value="KAJ3226956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ10"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04048">
        <property type="entry name" value="C2A_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04047">
        <property type="entry name" value="C2B_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000042">
        <property type="entry name" value="Copine 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037768">
        <property type="entry name" value="C2B_Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="31"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="160"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="633"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="766"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="641"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="766"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="798"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3226956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="821" mass="92726" checksum="EA284EBCB54B9CDB" modified="2024-05-29" version="1">MQIAICANIFLRQGSCRLLFKSQNLTIAKIPYNEFEFVGYPSPSYRMNSTTLELRISCQNLFNPINPLNKISPQVILYIKSNQNQSWINLGKTETIKDSISPEFSKFFTIEYYFEEVQDLKFELINNDGHHNSESHAPIACIETTLANIVTNVGKTLKKKLKRGLFVIVAEEVILNQKEKCRFRFSARNLDKKDFFGKSDPYFTISKAKEDGSFTLVYRSDPIMKTLDPIWPRFDISLSELCAGDKKRNLRFQIFDWNKSGNHELIGSFNTNIEEILKKLKNNSIEFEIKNFDLMVKKKGYQNSGIFRIIQFDLIKIPSFLDYISGGMSLDFAVGIDFTASNGDILHPASLHFRNENSFNQYQQAILAIGRILEIYDSTKSFPCYGFGAKLGSLNAPTNHCFPLNGNEYFPEVNGCQGILEAYNFALNNYVILHGPTNFSPIIDAMADLVKRELLRFGNGSFYKVLLILTDGAVTDTDQTINSIIEASTLPFSIIIVGVGNKNDWNSLIHLTSVDGYLNNDDGFYKTAARDIVQFVPFIKNRANLAQVVLKEIPKQIVDYMVSHSIKPNPPQFNLSSDYLERNSNSLDRNSNSMGSYVQRLGSFSLTRSNSTHLLVHPNAYRMQEESVIRTDLDSPPEYTETATSTSVTNHSFSTLTQNRYPDIIDSNTVSPNLRPNYRSSTLFSTSGSSDSPNLHYIHSVTSNNINSSNFRSENSLGRSFTANSPPSFSSSPVLGFHLSEPFLEMSSNSLNERFQHLHINNVSGSNNYRSQTSPIPINSPPTNVNNGIHVLRGPRSPNFNKNHIHSNSNDNTSFVSRFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZH0</accession>
    <name>A0AAD5XZH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZH0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="88" mass="10058" checksum="0561EA77EA2E88F2" modified="2024-05-29" version="1">MCISERLKKSSIFFSKSSSQKKPEIDLTVMEKSLNQTTTETKENFLFSPCITYICSENAIQNCNSKLSSLKKNSPLLYDDFMDIELVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZH9</accession>
    <name>A0AAD5XZH9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Eukaryotic translation initiation factor 4E</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007817</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF8">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="23233" checksum="652C59EB319E1585" modified="2024-05-29" version="1">MATTEELEERVTVFEDPINFSIKHPLNTQWTLWFDNPNKKPQSNHWEANLKSIINFDTVEDFWGVYNHAVPPSKLPLGSNYHLFRNGIKPAWEDPKNENGGKWTISILKPKKDELLDNAWMNTMMSCIGEFSEFSEEICGAVCAVRKANDRIHLWLSCNDREKCETIGRHLKEAAGVSGENIKYEPHPKDFKEKAKPIYEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZJ6</accession>
    <name>A0AAD5XZJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005521</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000433">
        <property type="protein sequence ID" value="KAJ3217308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZJ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012445">
        <property type="entry name" value="ATG101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
        <property type="entry name" value="ATG101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="21965" checksum="89F5D8B61F91B51A" modified="2024-05-29" version="1">MLNSKIFRFDLTVEQYYIRDVLRALIHSIIFHRSFNELIPLEVHVDLLNVTYVKIDDPEVEKMIQEKIANFTKSFINNSKQGQILISFKNGKESKAKYWFSKSNEDAIFEQWQINITLIRAKTEREQIDCRKTLSTLLLEKLIEISHITNEDNDHVPAITNADQYPFPFQIEMASNDQNSWKLPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0B0</accession>
    <name>A0AAD5Y0B0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chromatin-remodeling complex subunit ies6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">IES6</name>
        <name evidence="6" type="ORF">HK099_008366</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000091">
        <property type="protein sequence ID" value="KAJ3224498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0B0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029525">
        <property type="entry name" value="INO80C/Ies6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200:SF1">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="5">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="136" mass="15714" checksum="D96B87D56284ACFA" modified="2024-05-29" version="1">MNAEENGCFNDVKIINSADLLKNPLINPSPSDIRSPKFKNSKTKKVIKSFKASALKQEKFKALKLNEKITNWNCDAPPQLLPPRKFCDVTGLEAHYTHPATSLRYHNKDVYYFIQNYLSKNEVIVNEYLNLRKNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0U4</accession>
    <name>A0AAD5Y0U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_006655</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tetraspanin (TM4SF) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000059">
        <property type="protein sequence ID" value="KAJ3225517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0U4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000301">
        <property type="entry name" value="Tetraspanin_animals"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF544">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002419">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002419-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3225517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="27338" checksum="9F5F770AF7B265A7" modified="2024-05-29" version="1">MPFLSRIGTFSFSRESCFAASGFMFVKNILLFINFLSLLAGLILIGGGGYIQSRSSGDIVNLSGSIAAGAIVIGCMITIISFLGCFGAANEKGMLLKTYFALLILLVVLEIGIGAAAYHKQEDLGVLIEDSWRNNAYANSSITESIKTLEISFKCCGLRNITDAPVPKNCASKFEWNTSCYDAVLGSMESSLDTIGATGLAMGLIELVAIVFSAVLFNRIAKKEKQGESLMTDSWRINRSKVQYGYQNYQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y120</accession>
    <name>A0AAD5Y120_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005643</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000045">
        <property type="protein sequence ID" value="KAJ3226058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y120"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF37">
        <property type="entry name" value="ABC1 FAMILY PROTEIN C10F6.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="104"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="551" mass="64321" checksum="EE36A74DE18FB4BD" modified="2024-05-29" version="1">MNRKLLKIGSVATGIFAADYFLLDNSLKRNLRTLSYGALITADYKLNFTIGNAEKIGSLHKRTAERISYVCRENGGLYIKFGQQIASLNHVLPEEYAEIFYKFFDEAPSADFERVIKIFKNDFGVHPDELFDEFSVHPIASASIAQVHSAKIKGTTTKVAIKIQKPEIKNQMFWDFQMYKFVTFCFEKLFDLPLCWSFDYIQRHFQSELDFINEGKNSEICAQHFSKVKNLRENCYVPKIYWDRSSSRVLTQEWIDGVKLNKTLLEKNSFSSKTVMEVVVDIFSNQIFRSGFVHCDPHQGNILIRPHPLQKNKPQIVLIDHGLYVSCSPEFVQNYALFWKSLFTQDSQTLEEIVKNWGMSDIQMFATMTLQKPWKKDVAIHIPQKPDLREIYEMQVEAKQRIQKFLTNTNLIPKELIFIGRNLNIVRSLNKHLNSPVNRINLMATCAVKSLGPDWSVWERNTMRDLSFKRYDYNKDFINSFIMFFKSRLNYLKFQTTLLVSAIGFRFSKTLQMLQYYILNTQSGGFEEHLDKQMKEASKKIGFEIRDPFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1B3</accession>
    <name>A0AAD5Y1B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">VASt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001269</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000134">
        <property type="protein sequence ID" value="KAJ3223347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1B3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140268">
        <property type="term" value="C:endoplasmic reticulum-plasma membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120015">
        <property type="term" value="F:sterol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="244"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="512" mass="58520" checksum="AD20A7AF0F889070" modified="2024-05-29" version="1">MEKNDLMVGSESDLFTFPDVRKSTSLSSISSRKSKSNRSKSDNFKQLQQKLPSHGLVHKDSAYFDSIFPDANESLIDDFSCALSRTILEQGRLYLTDNALYFSSAFFEPLILHYEKIKKITPNNFIFTTGIDIATTDGKDYRIQSFLPGYRDMALSYLEKLWLTRITALALAKNSRPNSEISLDFNNTQHQQQSEISESTLNSFTKTVNNADIQENTNNSVTPESNLNRDSVIDCDCLLTIHDQYFTLVDDIIKVNVKRLFEILFFTKGDIEGENFFKNFLEKRGCTSLHIGSWKENSEHEKEYSDYETLHAGLEREVQYKISLGGGCYQPLTKVKSRILTFSHECICIQSITKAIEVPFGKNFQTNVRFCILNQDIDSCRIVISYEVEFTGTVPMKSLVLNPLKSEIIKYHEDFKAQLKGYIKALSNNDTVTSDQATHAKIEDTNKVNIVKNNINVIPDGSEPVASSRYTENTFTKAANLQHSDMEKKFNEKLNYLNFKLNLILFRIKEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1H7</accession>
    <name>A0AAD5Y1H7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Ribosomal back-translocase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_000813</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GTP-binding elongation factor family. LepA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000120">
        <property type="protein sequence ID" value="KAJ3223701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1H7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097177">
        <property type="term" value="F:mitochondrial ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03699">
        <property type="entry name" value="EF4_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000015">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000007">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2570:FF:000001">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000004">
        <property type="entry name" value="Translation factor GUF1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="entry name" value="Elongation factor 4, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512:SF7">
        <property type="entry name" value="TRANSLATION FACTOR GUF1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="TRANSLATION FACTOR GUF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="3"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Elongation factor EFG" evidence="11">
        <location>
            <begin position="294"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="GTP-binding protein LepA C-terminal" evidence="12">
        <location>
            <begin position="382"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="781"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="19"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="845" mass="96178" checksum="848FA6E177B2F9DF" modified="2024-05-29" version="1">MANFYLAFCQDLKIIPVLNKIDLPGANVEKVTSQIRQAFEVDEETEIISISAKTGINVDKILPMIIEQVPSPSFKAEDKFRCLLFDSWYDQYVGVVCLIAVGDGKLSLGDKIASAATGIAYDVSELGFMHPDQTPCKALYAGQVGYVVLNMKTTKEAHIGDTYFHAKEKKENIKLFPEFEMVKSMVFSGLYPVDSSDYSKLSEALDRLTLNDSSVSVVKESSMALGQGFRVGFLGRLHMDVFQQRLNDEYGAAVINTQPTVTYKIRYHTGEEELIQNPADFPEGDDIGKIEAFFEPIVMATLILPAHCIGNMMSLCESHRGEIDSTNFLDETRVMIKYKLPLAEILIDFHNQVKSRSSGYASFDYEEIGYRESDLVKVNFLLNGKVIDALSAIVHRGDSVRNAKNGVLKLKKVMERDLIDIAIQGSINGKIVSRESIKALRKDVTAKCYGGDVTRRMKLLDKQKEGKKRMKSLSHALFVDIDTPHLISLVSQALVEETKNQITQTKLSRFHSKSKPLITIKDYLARILRYASVDKVILMVVLIYIDRIQLRNPNFSICILSIHRFIITGVMVATKALCDSYLTNTMYAKIGGLSVVELNILELEFLFLVDFHLSSTIEQVQEKYTQLRFDCTTCKENHGRKCSNYRPCRFCARNGHRDSCVDQQLPLSPENLLKLLSIKNFAENAERKNNLNNALEEYIKGIELIKEIAFKLFALKKNVLPSEKKSWYSYFTFPYLIPFLNKIAKIHLELGNFESCLNFTIQSQKNSELRYDFNRKILKFLDMENYDLEKLKAEIKSIECEARLKMNKLSENEKFPIMFSNKYNGLETLNDFVSLNKMHLSFLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y221</accession>
    <name>A0AAD5Y221_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MCCC1</name>
        <name evidence="11" type="ORF">HK099_000850</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000028">
        <property type="entry name" value="Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000010">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF33">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="10">
        <location>
            <begin position="15"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="116"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="608"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="958"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1002"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1063"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1537"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="960"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1551"/>
            <end position="1561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1578" mass="177052" checksum="20DF3688514BAC21" modified="2024-05-29" version="1">MRQRRFLSQTTHKPLFDKILIANRGEIACRVMKTAKKLGVKTVAVFSDADRDSMHTKLADEAWNIGPAASSESYLRMDKIIQVAKDSGAQAIHPGYGFLSENSDFAKKVTDSGLTFIGPPNANVPVVPGYHGENQEPEFLKKKADSMGYPVLIKAIKGGGGKGMRIVEKSEDFMMMLESSKREAMKSFSDDKVLVEKYLTVPRHVEVQVFADKLGNAVYLFERDCSVQRRHQKVLEEAPAPGLSEALRKDLGEKAVAAAKAVGYVGAGTVEFILDTLDNKFYFMEMNTRLQVEHPVTEMVTNTDLVHWQLEVAAGNRLPLLQKDLKLDGHAFEARIYAENPRNNFLPDVGPLIHLRPPQPAKNSVRIETGVTEGDAVSVHYDPMICKLVVKGRDRSDALRILRKALGEFEVVGPNTNISFLQSLASSPDFIAGDVETGFIEKHKQELFPEEIDFDPLDVAKAALGLLYQKQQITSQLSASSYDATSPWGQLKDLRLNNFKTSRFQFLNPNKEENQEKTAVELSYDCQSNNYNISVMQSASGKNFNFNDVLVYENTSTESNRLKNQNDYIVEINGKRSKCSIINFEEKLHLFCDGKHTILGYPMPEYLKANSDVKVGDVITPMPCKISQILCKAGEKVEIGQPLIILEAMKMEHVIRSPIAGVVKNIHYNLGEIVAERKRLPPCHIIFVKENHQNKMVDYRNSNSDHTQHIQQQNLHSNATSNTRYNMLLAFDDNNDLGKPHNLSFDVSQPYTNCTDFTSSESATQLHLSISSPNTLPPSDYSREHILSDYWQNSNDSIQNIPTPISTPPILSSINQTGNFGVQHFEPNLGQESISLDIQQMQQYNDIQYILSPPLQFNSLPQSSFAEQSNVNTKVENNSPFHRSLSQHSIPENTTNGNCGENISVSYTQFSPFNSGYSPSLVQTSYLDDSVKLTQSPSRSKNQMNRSFKNNLNNIENANAHQTSSPTNTTISAGSLKNYDDSPKNNLNDLIGPKTLFGYSDASNSQMSTSRSNFGAGSPITSSSTQVDDNSASSPSNKLPFSFLTPLETPTLVDSSTSLPNTGLFPQIKDQSSSSNESHRQLKRNLGIRTKVIASTQGKDGKLRKPKIMKEALAFCNKCNKEFATLILHGTETELSQDYFIEMICWDCEYESADPNPTRNPDLETKLPKQSRCATIDSTPKGRKMKAECECCKRIIATGGVCAGTRENADWSDPGFGVEIICAYCREKYGFCTECGGGNRFRTGKWRPLELFEENRRTCKFSHNRIGKKPIIYQTFRVPDEFSRENYKCVHGEGCSGCSFDMVLAQLKEMYLDRKLFSYAVPIIMETIPTMMTWQKLKKKIEMHWNAIEIALTTRPEPHIRTYVDLSFIPPPSPRRKNKSSKEFSSGPIASQVIAGFVCGHWDIKKRTFFIGQRCNCGVGGDPCSMILEMTKNLIARVSKDLEYMKNCQPPTLAFCTGFTRFFVRTTLDFLKNGEDRTRLIPDKEFTHTDFSFTRIGFRTVADYKNLDQEMISELCPKTNDETLYVVNIKDLKKPENSNMSCANPRKKLKSNNVDGENQDSSAKHIKNVPIIQKNGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y240</accession>
    <name>A0AAD5Y240_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y240"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046132">
        <property type="term" value="P:pyrimidine ribonucleoside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3228451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="197" mass="21540" checksum="3E3A3668FBBA8EDB" modified="2024-05-29" version="1">MLQYQQEFIDFLIENKVLSFGSFKLKSGRTSPYFFNAGLFNTGSSLAKLGEFYAKALVESKIEYDVLFGPAYKGIPLVATTEAKNHGEGGIIVGSPLKGKIFVIDDVITAGTAIRESVNIINENGAKLCGVLIAIDRQEKAGNDSNLSAIGQVEKDFNCPVVSIVKLDHILEYLKLKSGFEKQIEEISAYKKLYGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2X9</accession>
    <name>A0AAD5Y2X9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ELMO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004788</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000035">
        <property type="protein sequence ID" value="KAJ3226478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2X9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017124">
        <property type="term" value="F:SH3 domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024574">
        <property type="entry name" value="ELMO_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11841">
        <property type="entry name" value="ELMO_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16457">
        <property type="entry name" value="PH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="2" id="KW-0581">Phagocytosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0729">SH3-binding</keyword>
    <feature type="domain" description="ELMO" evidence="5">
        <location>
            <begin position="296"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="812" mass="94381" checksum="976AC9F8E31A38E9" modified="2024-05-29" version="1">MKLKVIFEPNSVELEVKEEEKIEELLKTILVKFNLTNKNPNDFILRMYDSNKILTNQNYSSLLPLNELNVVKLTFTQKIEAKIMSEQLRNKEDSLQIKKTVFILQKSLMEFEFVEEFIENGGVAGLITVIFAAEGNTLAYALTAILNLWEHDVGWDDLSIEFIDFLIKVVVEQNLVNICRPATGIISKILIHMNKIQHLINKFNFEMIDSIIKRKKDFWKTLVERLKLTDYQLQSNSLQLIIVILRNCGAAYKGDVLRNLEQFEIRPILLKLIHSKPSEELGIQLIGFQSLYKQDMHLQKKKSILKLATKGELEFVQLLKLSKVTIKDDGFKYRLLGFSTENPRKDFVRVGVLGLETILEFAKKNEDLFFQMIHEQQTKEFEKRCPFGIASVEIVEILCDCWEISVGYATATNFEPLLFAFHKVFLILLKCYFKLWKEMELWNCTNDLVRVSLLIRSQFKYSVRLTPIFDENFLLIFEKHMLDFQLAQLKNRQSIENELEDDLYQKIHVRNLREKFYKENYEFVKKQRIDCLLKGNFFLLEKNNIEQQLQQKFKFGVGSGLKTPVNNYRFFKLSNNLKNLHYGDFPNDTFQPILEDLTEKFDISMISEIQFGSNVKRPSTSKPLKNNDKSLKENNYQFQLLQTTNQIPIILSSFQCKSEEELSEWVDGFNFLLEKSVTTRHTVQYIQDLTDIAVRLSLLDLTGEGTELPNLTLEVPELPANLEFKLTEESGFLWDSSHNLNTSISETVVASVDINNFSGGTEGFLKNLQNSKEHVASSNTVNNNLILSEDLKNEFLILDGVFEGELKTFLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2Z7</accession>
    <name>A0AAD5Y2Z7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_004609</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2Z7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47235">
        <property type="entry name" value="BLR6548 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47235:SF1">
        <property type="entry name" value="BLR6548 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041941687" description="G-protein coupled receptors family 3 profile domain-containing protein" evidence="9">
        <location>
            <begin position="19"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="813"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="847"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="881"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="922"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="970"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1003"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1032"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="10">
        <location>
            <begin position="811"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1089"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1089"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1124"/>
            <end position="1149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3226582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1187" mass="134276" checksum="4F269AE92CBD7AAC" modified="2024-05-29" version="1">MKFFELLFYVLLIRASVSFREIKLGQSCAITGNSRFIGIRLKDGLDAAFSRFNTEEATTLGFSIKLITLDDGYEIETAKNNLIDFIENEEVFALIGTMGTPIVASELNFTRRYVSDKINREFIPVIGHFSGGMSLRAREGEPFPYQIINIRGSYFDESRAMIYFLLEHLSGIKRISVFYQKDAYGQTGLDGITKSLQEKSLSVHSTGHYERNTANVTEGINQIFKGKPQAICMFGTYQAIAPFVVAVKKINPNVVFMAVTFTSPAAVLNEMIKLGGVESSRNFYVTQGLPLYTSKSSSLVKELIRDHSAYQKVNSTVTSVHALFLEGYVTARFAIEIFKKMKLNGIPPEEFTNESFLKTVYSTSIFDIGDLRIGPFGDTSCDLIGAGCRCNQGARKIWISAVNETNQEYYEVPSTNFQFATCGVRFQLPKEIFFAISTNLETSRGMAFVNGLKIAFNAMNEKGVMNGITVSLLINNDGDNATVANDFAKTLKDKKVIALLLPMWNSSFSEARKTLNENSIPIVNDLRVYTSSPSVIQLIPSFFDNVQLLFTFAFNQLRVNTFSAIISTEFHEKEKELKDYLTSSYDQSLSSVILINYDEEIPFFTEPGAIFIIGDESFTYITINKLEAKFVKSYYLIPTFVSSHDLKEKIPAQAEEKTFCTSSVLDYSESDNLIVRSFYKDAESIINYDLSESEYISYLTGLFVVEVLRRSKNFTDPIEFINSIYTTRVFQFQEETFSGFFHHTIFNDTHAFSQNTYDEVDGDGGFCNYGYFENFVTEVKNINKKYHVEVGNNQNLCLNSKKIYHHRNKISEVFMQIFSIIGIIITILSIIYIILVRHENLVKASEINILITSLVGIAMMYCIVLIHVSFHKFDSCMLIQYLDNISFCFIFGGMVAKSYRVAVVLRKSKNIDVRNTFVKQKYFLYFVVFGSTAAICIYLVVWHLMNPKKLLLEDYNGTNIFECVQKYSNIWILVPIFFQLVFIVIGLFLTIQTRASWNQFSEYKLNGIAMYNFSFSMIIIYLVEFAVNDLDLALLVTSIIILYNATVKIFLTLGNKLSFKKEDLRVLRNSVSKNSSFFSEKKFKIPVTDSEQGVEGTSSTSSSPRITENSSSKITNNSSLKIANDSNSKVNKSSGSKINNNSNSKVNNLEVKKNEDSKSASIQSPVVEKLPRVNGEINPKRNSVIMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y369</accession>
    <name>A0AAD5Y369_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">L-serine ammonia-lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005714</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y369"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051318">
        <property type="entry name" value="Fe-S_L-Ser"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30182">
        <property type="entry name" value="L-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30182:SF1">
        <property type="entry name" value="L-SERINE DEHYDRATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="Serine metabolism enzymes domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine dehydratase beta chain" evidence="10">
        <location>
            <begin position="62"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Serine dehydratase-like alpha subunit" evidence="9">
        <location>
            <begin position="226"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3226008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="56341" checksum="424427587CD4FD91" modified="2024-05-29" version="1">MLRNLAKHSGVLKIKKYETISGKSHYFLLFKKHYSTNVYNVVDKSSTVSAEKSELVQHAVLSTFDLFSIGIGPSSSHTVGPMRAARIFVTELEEHNVLADTEQMRVDLYGSLALTGKGHGTDSAVCKTGELIATNEFFSIGGGFVVNEKTTPITHQKENIFYKDNRIDHVSLNLDSELHIENVTLDSEKKIISSDTTSITRTESTSISAALPFHDAESLLRVCERENLSIAQVVYKNELHWRSTEEIKARTLNIWNVMNQSIENGISAEEKYLPGTLHVRRRAPVLYKKLMAGLADYAGLTSPPSILLHSPSSSSVSNFNLVKNYERSNDVLIKKPRIYKRSIPALDWINLYAIAVNEENAAGGRVVTAPTNGAAGVIPAVIKLLTSAAIGMLYKRGASISAAEMGCQGEVGVACSMAAAAFTAVMGGTVEQVENAAEIAMEHNLGLTCDPIGGLVQIPCIERNALGAVKAAQLSLNGDGYHRVSLDQVIETMRQTGIDMQSKYKETSQGGLAVNVPVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3N9</accession>
    <name>A0AAD5Y3N9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicastrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">HK099_003330</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nicastrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3N9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01805">
        <property type="entry name" value="Ubl_Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000002">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000003">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.540">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041084">
        <property type="entry name" value="Ncstrn_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008710">
        <property type="entry name" value="Nicastrin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015360">
        <property type="entry name" value="XPC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036353">
        <property type="entry name" value="XPC-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00601">
        <property type="entry name" value="rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21092">
        <property type="entry name" value="NICASTRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21092:SF0">
        <property type="entry name" value="NICASTRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18266">
        <property type="entry name" value="Ncstrn_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05450">
        <property type="entry name" value="Nicastrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09280">
        <property type="entry name" value="XPC-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101238">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 16" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042127397" description="Nicastrin" evidence="16">
        <location>
            <begin position="19"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="18">
        <location>
            <begin position="522"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="17">
        <location>
            <begin position="630"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="17">
        <location>
            <begin position="819"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="576"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="677"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="791"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="682"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3227111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="866" mass="93823" checksum="53D628C182F102A1" modified="2024-05-29" version="1">MNILEIFKLFILLKYVISEVDYTGTLDNQIYQKLISLASVKTMNNTNNFGGGHFLKNVGILYMVNSKEDVDKFFQSSLKPSIFVLDYKFLTYSLESYIKYETKENLRGIFILKNKNSSFTGLNVNFERTCLNCEISLYKNDPKIHSWNPKGNAFSFYNFKIPIFAIPEDLGTEFKQSSNEIVTAAKFNEDHNYDHSMLYSAQFFSQQNGTIDSLTCLRRGRCLPIGGLSIWATFSETIAKSDGKEIVVVSSQLDSTALIKDLALGASTLSGVAAALAVADAISKLPNNPGTFEKHILFTFFNGEQWGLAGSSRFVNDISKSFVCASQSAPFCPVESANSCGLPCRPSTDYTGIDFSKIHSIIEFSHIGGFGVNLKGSTTPNNVYLHMDDIETVSKSSLGGLFNNSTILATKFNQSSNVFFTFSNAANNFKDNLKLPPSSAQSFLLKNRSIPAIVIGDFQTGFSSPFFGSELDDNSQLNDENIALICGVSLTIANETAKAVYQVASGTKDSVPDQIQANCTLVSDLKKKVAEHENITVEQQKLIHSGKILENEKLLSHYNVKEKDFLVLMVTKTAVRTTPKPEVSEPTKTNSASPAQPASNPTSSAVAAEATTKPASASLENADSNLVAGSAYDSATQNLVEMGFEISQVKAAMRAAFNNPDRAAEYLMTGIPEGIEAPQNPVPSATTPSAPATPANAANPNVPSGYENLFTAAANAQRPSSTNNPANENTFAFLRNSPQFQQLRQLVQTQPQLLQPVLQQLGQANPQLLELINGNQDAFLSLLMEGGEGAAATEGGATGENPAGAGNTAPPNQQYISVTPEEEAAINRLAGLGFDRQMAIEAFFACDKNEELAANYLFDAQNGGDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSF6</accession>
    <name>A0AAD5TSF6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="4">DHBP synthase</shortName>
            <ecNumber evidence="4">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003284</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010002177">
        <property type="protein sequence ID" value="KAJ3199152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSF6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF18">
        <property type="entry name" value="3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3199152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="216" mass="24151" checksum="E14B60C78EDCD437" modified="2024-05-29" version="1" fragment="single">KGNIVIVVDNEDRENEGDFVIAAEDMTTEKMAFFVRYSGGVICIPALSSRLDELNLPMMVNNNEDTFRTAYTVSVDYKHGTTTGISAHDRALTCRSIAQPSKTTMSNDFRRPGHCFPLRYTEGGVLKRIGHTEASVDLCILAGKNPCAAISEVVSVKNENFEFLKSQNGSVYLENNSNDEIGSMARRNELYSLSRMWGIKMISISDLRQYRVENNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSY9</accession>
    <name>A0AAD5TSY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine-threonine kinase receptor-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TIF34</name>
        <name evidence="6" type="ORF">HK099_002950</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002004">
        <property type="protein sequence ID" value="KAJ3199947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSY9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF1">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="26"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3199947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="84" mass="9370" checksum="FA93CCD834BE50C1" modified="2024-05-29" version="1" fragment="single">DLIFTTSKDNKPNIWYSHNGEKLGTFDGHKGTVWDIACDHLSKTALSAGADSTMRLWDVQTGKSLFVWKFVSGCRSVDYSQGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT92</accession>
    <name>A0AAD5TT92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001838">
        <property type="protein sequence ID" value="KAJ3200780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT92"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="77" mass="9120" checksum="6F47E8E1E4C8B5F4" modified="2024-05-29" version="1" fragment="single">MSIEEVLEHKISKKEEKTKKIKILMQSFWHGVTPSEQKMINLVTENNRKLKKKGSWNDDDDTCLKKKRGKKEFLSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTA2</accession>
    <name>A0AAD5TTA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Plasma membrane proteolipid Pmp3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PMP3</name>
        <name evidence="7" type="ORF">HK099_002489</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001825">
        <property type="protein sequence ID" value="KAJ3200844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTA2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF42">
        <property type="entry name" value="UPF0057 MEMBRANE PROTEIN ZK632.10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3200844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="68" mass="7677" checksum="F31BAA1F284076E6" modified="2024-05-29" version="1">MGSGFIDFLSILFAILLPPLGVFIERGCDVDFWINVLLTILGFIPGVVHAIWVILSTREKRERGYVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTB4</accession>
    <name>A0AAD5TTB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001900">
        <property type="protein sequence ID" value="KAJ3200462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTB4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="214"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3200462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="44370" checksum="85F052A294B95249" modified="2024-05-29" version="1">MEWLGDFFLENKQISTFLLQSYSFSLLTAPLIVEETLSQTQYQSDEDYENISYANLHLKTLNEGVWQNIRAIVESEYDGTIALLKGHITDGFYNFTFQGLRPILEESLNDALDIFDDNNPSTNILSHVILGGLLSPLELVKTRVIVESSLSTRKTYYNSIHALTSIPLEEKSSFLVMYSPRLLLPSIFIHALSPMISYFTTYLIEVELDLNPTYTPLYFKIASVLAIGLKVLITTPFEMARKRLMIQRIHKTENESQNTNPLKETCVQVSPIYYTGIFNCIKKIVLEEGKLKKRKRNLNNIQSDTNFNIYKNFSTVNLVSHPTTVTDSGFSDNGSNFSSEKKKNFKQYWAGFKSLYRGFWSRYTIEVLRYFLKELDDDLMDEFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTR9</accession>
    <name>A0AAD5TTR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001636">
        <property type="protein sequence ID" value="KAJ3202006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="461" mass="52211" checksum="8BC7F67BFE4F51CA" modified="2024-05-29" version="1" fragment="single">AGLRTELRTEVAGLRTELRTEVAGLKTELRTEVAGLKTEVAGLRADVKKNINDLCKFKKECTNNFKTILDSIGSVYEIVARHELIKDYGEHYARPFRMQDMHGVARLILPKRPFLQSEKIDITTNTTEILNDRSNSLIASIVDNDHEFKKSLNLAFSSISRKHSKRSWVQDLKKIFTGYETLKVISEKVTYLKRKNGLAVAFITSTFIINPSKWADENDIPLRSCLELDIRGSCGMMNSNGVDIEVGEIKSNEKNDTKGSRQLAIALCTLAYSVNVLKLTANLKGILYSPDKSKNYFENEDELVWPDNFVKKVSFPDINEIWFQLVDSEGNPYNKTSPSTVLVQQDTNINVLRKLIKVEYPNTLLHIDAGQLEIYESVAKLRDNSPINPKTLVLKLDNTEDLVVVVPENLLKRVKKDNQEDIDSLDQVKLFIHNEIAEEKTVFKKSSSFDNIDIDGIGKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUD0</accession>
    <name>A0AAD5TUD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001395">
        <property type="protein sequence ID" value="KAJ3203674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUD0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="99" mass="11690" checksum="63BE9FD1A8A3AD5A" modified="2024-05-29" version="1" fragment="single">MKVCNCNEEQEDVYNSSYEADEIDALSNLEQTNRSDFNKSNEHYQIYHQPTVTITIPKKMETVTLIRDLDGYFNVFGMKIRDPLFVQEFVDYKFGEAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUP0</accession>
    <name>A0AAD5TUP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001024</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001266">
        <property type="protein sequence ID" value="KAJ3204778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUP0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3204778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="264" mass="30721" checksum="62495935D8B2FBB7" modified="2024-05-29" version="1">MKRLISTTSVILDSLTKPDFKGSRPEVYQKIKNLIKTEPINKIKTTLPKERFTSIYEKVSKARPKSTTLKKVSTAVKSRESLPKNLALKHFLYRLKRDGGDKILNFEMNFLHIEYTRFLTLCDQVKGLNLDEALKQLHFHRKPITKHFNKGLKAAIVKAKLNNFDLKKTYIAEVYTVENGGIFSKLLMNRYVRGRARYGSSPHVKSALLKFILQERSKPFFKRVSDPLEYIREKMRSNLRVKVKSANSVFSLEKKIKPEKIVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUS3</accession>
    <name>A0AAD5TUS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">protein xylosyltransferase</fullName>
            <ecNumber evidence="6">2.4.2.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Peptide O-xylosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">HK099_000952</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>UDP-alpha-D-xylose + L-seryl-[protein] = 3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:12567"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132085"/>
            <dbReference type="EC" id="2.4.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; chondroitin sulfate biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Glycan metabolism; heparan sulfate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 14 family. XylT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.26" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010001242">
        <property type="protein sequence ID" value="KAJ3205022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUS3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030158">
        <property type="term" value="F:protein xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050650">
        <property type="term" value="P:chondroitin sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015012">
        <property type="term" value="P:heparan sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003406">
        <property type="entry name" value="Glyco_trans_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043538">
        <property type="entry name" value="XYLT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025:SF3">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02485">
        <property type="entry name" value="Branch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3205022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="258" mass="31113" checksum="748CFBCF67D72684" modified="2024-05-29" version="1">MVDSFFLSWKRRSGKCWRQGRGRDGSWEEKGDDRALGFFELADIADWDYVVNLSANDYTLRSPKFVYKYLQTTNPKKLWINFLKETREEKLKRLESPYLMLPNKSGLKEEKFDIFLKPKRNFFLKNDFFPVKHSQWMILTKEFIDFIRTDQKVLLFLAWTEHTWVSDEFFFGMVALYSHPDKIINDNKRFINFKDKTEKHPIWLNYNTSSLFLKKTTNFTKDNNQNNFFWFRKVKISQDIDLKNAVDLERNLADLSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVE9</accession>
    <name>A0AAD5TVE9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000144</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001018">
        <property type="protein sequence ID" value="KAJ3208020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVE9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042054946" description="Peptidase S1 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="20"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3208020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="285" mass="31442" checksum="ED96F07ACEDA3D7D" modified="2024-05-29" version="1">MLNSLLLASTLILKAISTPIVGGTEVGSNHVYPWMGMQQSNASWVSNDGSFHQSCGGSMIRENVLVTAAHCHVIITNLNQLKVFSHVYDSDKVVEEQAIEFKVVKIIKHEKFDGVGSNPPNAFDISLYILEQVSNPSNRKVETIEVASFDPNTINDQGPIKTIGWGAMTDISVNANQSKTLRETELQLVTLDYCTEIYKQYYTFDKVGPEFLCANDGNVGLRSICYGDSGGPSFTIENNKPILQGISSWVEGYCEAASIKSVPVLYVRASYFKNWIEEKLALEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVG4</accession>
    <name>A0AAD5TVG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-tubulin N-acetyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ATAT1</name>
        <name evidence="5" type="ORF">HK099_008404</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000918">
        <property type="protein sequence ID" value="KAJ3209898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVG4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019799">
        <property type="term" value="F:tubulin N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038746">
        <property type="entry name" value="Atat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007965">
        <property type="entry name" value="GNAT_ATAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12327">
        <property type="entry name" value="ALPHA-TUBULIN N-ACETYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12327:SF0">
        <property type="entry name" value="ALPHA-TUBULIN N-ACETYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05301">
        <property type="entry name" value="Acetyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51730">
        <property type="entry name" value="GNAT_ATAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="182"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3209898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="38392" checksum="86FC272CBFD1AA06" modified="2024-05-29" version="1" fragment="single">NHRIYFISKSDTTQDLLLQRKKTTVLGMLKIGNKNLFAMDDFGRHIQISPLCVLDFYVPEKCQRKGYGKKLFDFMLKIEKEIPAHLAYDRPSPKLVSFLMKHYHLSKQIPQANKFLIFKEFGLNEMENIEYSKKNQYINGKITKYKLEPLIPYYKHCLSREKIENEYLKNAVADLKEKSSTDVTGINNNTAKENELNDNQKSAESSSTANFNENSRNNQQPVDLPKSVNLIQGRELQLVRRLLVREKEEQQQQQRYKCFGNALPLPSIRDLRGGAASLLGSYSGTGDGIAVGRLRRAKIESQMNKLENRTFGLPSGFGMHKRLNKINLSVSEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVT8</accession>
    <name>A0AAD5TVT8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001921">
        <property type="protein sequence ID" value="KAJ3200360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVT8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="27177" checksum="F89933E872AC926D" modified="2024-05-29" version="1">MAKFIDIPIEIFQIILKNEPLETTKNLILTNKYFTRNLKLQFTQIDYLIATNFLDQSILLNGTEGRKFLSDLVFLKNFTSIHPHAMLKVWISLRDIFFKELDANLKLDKTVTEILFAHAELKSNGDRNSLFSTAAIYGDTALVDTLLKVSNKRKEDLRPMINYALGYASLYGQLDIVNRLIEETMKLNDFKFLAKMFTIALKNGAAQNHLFCVEYTLKKSAELNITLQTGQSLQLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVW3</accession>
    <name>A0AAD5TVW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000814">
        <property type="protein sequence ID" value="KAJ3211779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF58">
        <property type="entry name" value="SOUL HEME-BINDING FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="125" mass="13905" checksum="436867627297CE13" modified="2024-05-29" version="1">MCAGYKPLSDYITGQNVSKSIDKKEVDEATPVLTSQSKPGEQTMTFLMPPKYTLDSIPLPLNTDVKLMRVPEHTVAVLKFSGHLNAKLVEVKEQQLRKACEEEGVKLDNDKNNVQVASYNPPCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW44</accession>
    <name>A0AAD5TW44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000774">
        <property type="protein sequence ID" value="KAJ3212537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW44"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="315" mass="36441" checksum="8F0E1186D8B6FE9F" modified="2024-05-29" version="1">MIVQFISITYLVFVILGWTAIACINGLKPELLPAVGKDTSGVLGKMELKRPIGFLNENDVLRSFFIAETILKNLGISAKNLAQRNHLANEIFAIYKNTEISFDAITTTISLLYLSRLALALKNDTFKKNFNRSSINPFKSWITSLLLADTFLNDFPAKITVWATVLKYSPADILKMRCQMLNAINFKLAVTDSELQDWFHYIEISFTTFKQKLYKLLDKSAVQRKKSIASQQVQNFHKLKFKKFKENSKYNKALDLIEKKRISSNLLKFNSDLKNENIALDDNKEKKKYIFEQHRFLCNVLMYTDLKMNDVKLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW71</accession>
    <name>A0AAD5TW71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001688">
        <property type="protein sequence ID" value="KAJ3201681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW71"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10977">
        <property type="entry name" value="CE4_PuuE_SpCDA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017625">
        <property type="entry name" value="PuuE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43123:SF1">
        <property type="entry name" value="POLYSACCHARIDE DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="60"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="306" mass="35347" checksum="45947201424F0C6F" modified="2024-05-29" version="1" fragment="single">LKGYGEKAPHPRWKKGAKIAISFVVNYEEGGENNVLLGDKGSEVFLNETPGGTSRQQRDLNMETQYEYGSRCGFWRLLRMFEKYEFKFTCYAVGKAIELNPEVVDAMESRGHEVASHNYRWIDYSTVDEATERQHVRDTIKAIQNASSRGNYPKGWYTGRLGLNSRKIVWEEYKKAGLELKYECDAYNDDLPYWKDMDGQGLLIIPYTLDQNDMKFCVPPGFTDPDAFYKYLKNTFDVLYEEGATLNQPKLMSVGLHCRLAGKPGRAAALNKFLEHVKSFKDDDVWVCTRSEIADHWREVHPFNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW97</accession>
    <name>A0AAD5TW97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bms1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007964</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000825">
        <property type="protein sequence ID" value="KAJ3211597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW97"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF1">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22298">
        <property type="entry name" value="Tsr1_G-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="7">
        <location>
            <begin position="190"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="548"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3211597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="991" mass="114199" checksum="F3DA3E343BD1295F" modified="2024-05-29" version="1">MTTFLLFYFNIVVFSNREIKKHVKDWNPAAFAVEAQQLYIDMNKAYLSDNKAKLATLVTMPMFDKLKALIEHQKNVKFVWKFEGEVEKPKLVYTRLSKAQFDAEDVNKTHMIVQCTVRVHTKQQNKPFKSKHATKGQLNKSKKGKVEKLSNKSLKKISTEKKVDRKNAAKVLQQKKRFELVNKNRIFKQAPKIIAVVPLCDDVDSEKFVNKILKFTQSSSTSNEFVNIETIKLERFNNQQVQFIPLKRNLLDILDAIKVADFCLFLLSANNEVDSFGDLIIKSIKGQGVPSIVSAIEHLNTNLQKNHTLIKKSLQTYLEFHFAGEQKLFTIDQEQDCWAALRYITSQTPKVIAWRDNHSYLLAEKVEFHSSVETEDVGSLKFTGYIRGKNLSANSLVHIQGYGDFQIEKISSANAPLKNKTNTLILEEKILAVPDKEKQESLLRENEPDEMDGEQTWPTEEELLEAEERVKLLSQGKKRKVLVPKGTSSYQASWIYNSDDESVGEDEEGDVEMGDKEISNEVFNNSDDEKELVDIDADEVLEGESNSRDDEINEELDLEEEKEQYENYLKARKKKFEEAQEDLEFPDEIDTPMDIPARVRFARYRGLKSFRTSPWDPYENLPIDYSRIFQFKNFSQTRKKILKEIQNQEEFDEEEDEDSKLKNSIDVGFYCQIYIKNFTKAGFENLKSNKFQPKLIFSLLPHEQKMSVLNFSITRPSLSAIAEELAIGASKDEEIFSMLENSSTKKSLNNVPNLVVNSGSLKDAQNNISIKLKDFKLPLEYVVKSKDEVLICSGFRRYLCRPIYSSNTRNGSNNVHKFERFLQPGNTMTGSVYLPIHFSPNPITVFKLPNAEEAKTSNKPIFIGTGSVLTNDPSRIVTKRIILTGHPFKVHKRSATIRYMFHDPADVDWFKPVQLFTKFGKKGHIKESLGTHGYMKCLFDVQLKQQDTVCMYLYKRVFPKWNSELFLEGKDCARNVFEGSCIDKETEMELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWC0</accession>
    <name>A0AAD5TWC0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coronin-2B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CORO2B_2</name>
        <name evidence="4" type="ORF">HK099_008151</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000867">
        <property type="protein sequence ID" value="KAJ3210910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWC0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF20">
        <property type="entry name" value="CORONIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="2">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="3">
        <location>
            <begin position="135"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3210910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="759" mass="84849" checksum="6387B2FB0815DAE0" modified="2024-05-29" version="1" fragment="single">MSRFSNVSKFKNSVLKTHKKEEYYHVEAHNSTDAPPFQATRSLFGLKNQSNNLQIHYLKNTGKNDSQKKNVVSTGNFKDFSFSNFSGNENFPVAIGCDDTTVKCFQISSVEEEIFSSKFLSALTGHRNRVDNVLFNPLTDSVLLSTSENEIIVWDLCKSAIINQFETSANDTIQQLSWNEFGNTFASVGKDNKIRLFDARNNANTLIGDAHSGVKPSRISHLINTYIVTTGFNQRRDREISIWDTRNSFSQPVYTYKIDNSQGVLNPIFDSDTGILFLAGKGDVAVRWFEVNTGSNNFDQTCFTPGTFQFSAPSTYISSALVSKFGLDVMSGEIDRLLLLSSDCKTIYPVSVTVPRKSYIDFHNDIFPDTKSDTTQPLTNSEYLEAKSLSSIPLFSLNPLRKIEKLKNNDLMENKDKNNFAPIQETTVEKLPSKNSEQLFNKKEIVDSLPHTAAQQVPKQPVTKTKPLPRTSLYRFTTGKASLTVRMDDLKGGSGGRIGVWKANAFGRLPPKIPCLINGADVLDFKFNPFEANELITAAEDGKIRLFVLPEDGLKEDLEIPHAIFSAHPAKITSILFHQTIKNLLFSSSPDLGTPCVHMFDISDWKQPIKLRTFSVSDNILSMAVGGKNQSLLATHQKDKSLKVFDICNGKLLQQTLSHEGTKACRLQFLGMETNFLCSVGFSKGSQREIKILDAENLSKIETFSFDTSPSILEPFFDEDTSLLFLSGRGDSIISIFDINLEEFKINFLTRFEGTGPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWE0</accession>
    <name>A0AAD5TWE0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001173">
        <property type="protein sequence ID" value="KAJ3205821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWE0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF40">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="252"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="444"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="648"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="728"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="799"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="935"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="997" mass="117249" checksum="7E720B2AADDB893C" modified="2024-05-29" version="1" fragment="single">MEEKVETEADQKKERLLKIARKKSSLNNLSEKAESKSQLSTNISTIPGLELKNELLDTTTANLSPKYTPGPDRILQYEKFSALSSGSPLSSPINSCPPEPRSITSYPQQPFISDFFSDPFPSNTEDMIDNSQSFNVNNETSQFLWDYVTRGRSLTRKVSINGTSRSRVNDRVSESFSPTSLIKGDLINENFPVNNESHYYDSVKRNDVSNFKSTSCELNFDANTNSSDKLKPFYLMESNALDETLDPKSSLITALQSRIEVLEGMLEHMQIDFSCLKNERDEIKYRLETEFEEKIKNFEKREAELEGKELNLKAQVFELEKEMDSSAKIAEKNLELKKSELEKSFKNKFEQLEKKEDMFNEKFTKFETEFKKFEIEKSNFQNLKLNFQKEHEQFFIEKENFFKLKDGNESESFKKLKFFENEEKRLKLFESKIYNFSEEVNLKDQNLKEAFDETEKKSKSLEEERNEIEKSQIALNDMKIKVENDCKEVNERFKLLEKEESLFFQNKSKWENEFKLNEESYQHKHCQLMEEISLQEEARKKFLDDKNLMENQIVQLCSREVALKKIYEELLKNTLQFEDDVKDFNFKCNSFYNDKEIFEIEKQKILDTERKLLDEAKIFKDLKIAFEKEKTAFSEKKASSRLISQHLLNEQSSEAEKLVSLKKKLDQEKRLLEFERNLLNEREEKNSKNLKNIEAKELEVKEEQHKLVKVHETFQVNLENLNKRESHLKTLMQEVEFKNTNLNNLINENNQLKADLENEKLSLNTREDHLKDEKLKIENEKDSILKNLKQTQSLVGEKFEILEEEKKKMDLTKENLEQEKKKLKFEQEELQLSKSELENQSCKLNEQLTWIEKEKGAINELRMKLDQDRIDFERNKLESGGKIAKKKAEKVTGEADSVSSILEEINAESIFKSSANTKPASSPSSSINKGDALVNRNYETELNYFKERIMNLENSNTIFQENIVNLNEKLDTKKRFEENDTKNIPSLEKEKIKNLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWK6</accession>
    <name>A0AAD5TWK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000824">
        <property type="protein sequence ID" value="KAJ3211610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWK6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3211610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="219" mass="25721" checksum="342ACD427D4884CC" modified="2024-05-29" version="1">MASKIQEVDDELNPIIDSDESEQEAEQLRNRKNPSKKRGRNLDDVFRKEDEENKKKLFGGSILIPVLVVIVILSACIPILDKVLSVYFPASDGRGSRKGKYRQNTQNQNQHQEKQYPKAEPDVVKKNYNLQSVSELKKKSVKDLKTLLWSQNIQYSDLSEKKDFINRFRETIVKRDLRRMTKKELKSALVKNLGYKKEDLRKIDTHEELIDLYYNHEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWT8</accession>
    <name>A0AAD5TWT8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001234">
        <property type="protein sequence ID" value="KAJ3205092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWT8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3205092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="290" mass="32974" checksum="0BF3B9450D5AB4E3" modified="2024-05-29" version="1" fragment="single">SSTISAALSNSLLKSPHLHSKRSSSKEKFQKDLKIRKDFIDKKIKNVEKLKKKKLKEGNSNDVKDSKVDNDLKKFDEKKFNVNEQKIESITPKKFLDVKKVNKHNLKPTLTKTRNIPTSTVNSFLSSTKVSSTITTAPSTSTNLTFSLPTTTSVMGTTNLSSQNNSNSSEPLPASTIALTSTTYPALSLSAFILMILIPSLFLFLLCFGFRFYKNLKKYNTNLEEQFLNSKRKKVSYKTSFDNDAKNFRKNFRFSQVIEEEEDSEVEMITALPMPVYLSEIFKDWDNSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWU1</accession>
    <name>A0AAD5TWU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TEL2, telomere maintenance protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TELO2</name>
        <name evidence="3" type="ORF">HK099_007552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TEL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000741">
        <property type="protein sequence ID" value="KAJ3213156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWU1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.720">
        <property type="entry name" value="Telomere length regulation protein 2, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038528">
        <property type="entry name" value="TEL2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051970">
        <property type="entry name" value="TEL2_Regulation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019337">
        <property type="entry name" value="Telomere_length_regulation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830:SF10">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10193">
        <property type="entry name" value="Telomere_reg-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomere length regulation protein conserved" evidence="2">
        <location>
            <begin position="417"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="734" mass="85011" checksum="FACB85F517C251F2" modified="2024-05-29" version="1">MSNILEFSDKDCQKTLNSIININDDNHKKIISNITSCLKTMNLRNFLKKENIQLLISIPERTSQYNPPPILTKNVYGNWLATQLLNYLIECKNDNDLDLENFSELITKMLRVGYHEILVNSWFYKLRSAFLLTEDNYLKKNWFQIMKSLGARELDKFVTTFVYKLKDGNMDKSSICNDVQYLSFFLGGLEVDLQSVFNVIPELSFILGHKLLLNFPFNSIRISRILMEFIKTSNLKDFISPEECLKRLIKTWSDPNFIHHSSDKQHLIICSNILLFISNLRKEDFVQWIGSSYVSGVQHYLECGADRIRIRGMVLTEQFAKFNPTDEKLDFELKVTAEVEELRKLLIPLNEVVNGKVVDDAFEEKSQTENFLSEDLFEYSTKVPLSEKINPLGDSDDEDEFIPYEINVKNELEITPPKHLLECLSYIKSSENPEKIEAGLVNMSGLLRKAKKLDLDSYCGEICLTLHLLQDNFELKDFNRLKVENLVSCLVMNPLVSSRYLIEQFYHRNQSIIQRVEILKAISLAAWEMGSLEFQNSSTQNFVDSIVKKEISHIGKTIRKSSNINKKKKTYKNEFGPIASNYFFFPLVASFDSQNVGFNIFTDDDTLMVFENFIKTLSVILGASKNTIQCRQICREFFKLLKSLKFSNLLNTSSKIPKNVQIAILNGFLVCLDILDKSIVEKVLGDLSELFYWAVNLYQYSEDFEIKKISLTVGLTIQKINNSFQEEFFKEVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXB7</accession>
    <name>A0AAD5TXB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Metallothionein expression activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ACE2_5</name>
        <name evidence="9" type="ORF">HK099_007073</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000659">
        <property type="protein sequence ID" value="KAJ3213990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXB7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000032">
        <property type="entry name" value="Krueppel-like factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="201"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="231"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="260"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3213990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="289" mass="33075" checksum="6579AB7F9AD44220" modified="2024-05-29" version="1">MEEPVFFDVFSLEMPSGVYSPDSGQYSIPVSNYFSDVISSNEDPSPGTDEITSSAELNRLQSTQFAYPIIHERNNVYGFDIDLSAYPGAPNFSNTENTPSIDDINLSNNYSTQQQYYTIAAYDTFFPFSTKQDLNDQFLPALPNTNNLGQEIKYPPYETLFQQQRPLQQLENSDKAKYKKKNNTRLKPGQISSTEEATEIFNCPHEGCTKVFNRQFNLKSHLKLHAPEKTFLCEQCPASFRRSHDLKRHCRSLHSAIKPFECKNCSKSFSRMDALRRHVGRPNNACFQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXC2</accession>
    <name>A0AAD5TXC2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7703 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000701">
        <property type="protein sequence ID" value="KAJ3213528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXC2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056120">
        <property type="entry name" value="DUF7703"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24802">
        <property type="entry name" value="DUF7703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7703" evidence="2">
        <location>
            <begin position="2"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="88" mass="10164" checksum="C807758C9D6E7047" modified="2024-05-29" version="1">MVSIEYADMYEYQIMFKVLLYSIKLKCEFFILNMITKAIRSNSLSGRELDSQASQVPQSIDLVSCSDQGQNSSRSPYDTRCNYKTIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXS4</accession>
    <name>A0AAD5TXS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methylmalonate-semialdehyde dehydrogenase (CoA acylating)</fullName>
            <ecNumber evidence="2">1.2.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.27" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000969">
        <property type="protein sequence ID" value="KAJ3208915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000002">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase (Acylating)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000003">
        <property type="entry name" value="Methylmalonate-semialdehyde dehydrogenase [acylating]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="MALONATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866:SF3">
        <property type="entry name" value="METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="44"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3208915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="529" mass="57226" checksum="A89C2EB5DAF5AD88" modified="2024-05-29" version="1">MLRSSTKSISLSVSLIKKRFLTVVSTSQLDKSVPKTPLYINGEFIDSKTDKWFELRNPATQKLVTYVPQATSDEMNLAGKIAGDAFKTWKKTSILTRQRVMLELQALIRENMDDIAKSITTEQGKTFADAKGDVLRGLQVVEHACSIPTLLMGEKLPVSRDMDTYSYKEPLGVVGGIMPFNFPAMIPLWVFPLAIACGNTCIIKPSERDPGATIMLAKLAEKAGVPKGVLNVIHGGVDAVNFVCDHPAIKAISFVGSDHAGKYIFQRGTANGKRVQSNLGAKNHGVIMPDANKNYTLNSLVGAAFGAAGQRCMALSTVVFVGKSKEWLPELVERAKQLKVSEGFVDGTDVCPLISADAKKRVESLIQSGVDQGATLLLDGRGSKPKNFETGNFVGPTILANVTKDMKCYTEEIFGPVLVCLNAETLDDALEIINANQYGNGTAIFTNSGSAARKFTEEVDVGQVGINVPIPVPLPMFSFTGSRGSIQGDLNFYGKTGVQFYTQLKTVTALWRHEDVTSTTATVNMPTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXS9</accession>
    <name>A0AAD5TXS9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000558">
        <property type="protein sequence ID" value="KAJ3215231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXS9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="135" mass="14053" checksum="0046D4CC8456D6F9" modified="2024-05-29" version="1" fragment="single">MNSTEESNLAPSVTADDKSSIGAQATEQVENVLTDDSSSTTKNIPTQVTTTKSDSVVPSLTTSTIKLETNINTKSRINGTSNLPSSTKNAIVLPTIGSKVKLPDVSPAINVNFSDKPFLPTGNLLDGADLTGSNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXU1</accession>
    <name>A0AAD5TXU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001702">
        <property type="protein sequence ID" value="KAJ3201597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXU1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="119" mass="12821" checksum="E78C554281BB16E3" modified="2024-05-29" version="1" fragment="single">INGALGRSCAGQVSQNPSRNRIGFNKNIAVFLSASTEEYSDDWYCSHNVGDMLMSAGFTVIYVSFGEIASVLENNKVEMYVQPGGFGTAADIYNEFTSSDVEAVKHFVSNGGNYLGNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYG9</accession>
    <name>A0AAD5TYG9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphopyruvate hydratase</fullName>
            <ecNumber evidence="3">4.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ENO1</name>
        <name evidence="13" type="ORF">HK099_005969</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Mg(2+) is required for catalysis and for stabilizing the dimer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000490">
        <property type="protein sequence ID" value="KAJ3216227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYG9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.10:FF:000001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000002">
        <property type="entry name" value="Enolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="12">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="11">
        <location>
            <begin position="143"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="372"/>
            <end position="375"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3216227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="437" mass="47088" checksum="017CB0E32E2BCB5A" modified="2024-05-29" version="1">MAIHKVFARQIFDSRGNPTVEVEVTTDKGIFRAAVPSGASTGVHEALELRDNDTSAYMGKGVQTACANVNNIVAPALVKENLDVTNQEAVDQFLLDLDGTKNKAKLGANAILGVSMAVCRAGAAEKNVPLYQHIGDLSGNSSPFVLPVPAFNVINGGSHAGNKLAMQEFMILPTGASNFSEAMKIGSEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQDNKEGLDLLVAAISKAGYTDKVKIGMDVAASEFYKEGKYDLNFKDANSDKSKWLSGEALADLYKSFVKDYPIVSIEDPFDQDDFDSYNKLTKAVSIQIVGDDLTVTNPERIQMAIDQKACNGLLLKVNQIGTVTESIKAAKLSQSDGWGVMVSHRSGETEDTFIADLVVGLKTGQIKTGAPCRSERLAKYNQLLRIEEELGSKSVYAGVHFRNPSKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYV9</accession>
    <name>A0AAD5TYV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001252">
        <property type="protein sequence ID" value="KAJ3204924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYV9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="23176" checksum="9BE063955A21E319" modified="2024-05-29" version="1" fragment="single">MQVQKEEILKNISKYFDKQIALTSVLVILTTGGLYLVYRSKMQAKRLPPVYKNSVPIFGMFFEFLKYSSIKKTYLVFGNMNKEEPIVSWSTFGMNGVTTNSAEASKLVLAKHLDYCRNEFAQNVFEDIAKYALFIIPTTNGGQQWKKHRKMLQPAFGPTHLKHGLEVGLEVCKSLSDSWKAMGETGRKNINIHKHFNCLTVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U012</accession>
    <name>A0AAD5U012_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spp2/MOS2 G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004759</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000346">
        <property type="protein sequence ID" value="KAJ3219241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U012"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045166">
        <property type="entry name" value="Spp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026822">
        <property type="entry name" value="Spp2/MOS2_G-patch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818">
        <property type="entry name" value="G PATCH AND KOW-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818:SF2">
        <property type="entry name" value="G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12656">
        <property type="entry name" value="G-patch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spp2/MOS2 G-patch" evidence="5">
        <location>
            <begin position="100"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="144" mass="16218" checksum="81BD6A3836653A45" modified="2024-05-29" version="1">MKRNNVFQDSDGGSSSDDSSSTAKKKSKKLVIPLIKKNNYNMSIEEKELVEKIVKDSTEAFSEENTNLKNIPLIQQNKIPNIDGVENEKDKLKLDLSHRPEQSTLEEYEDVSVEEFGLALMRGMGWKDGMSVELNVNSKIVVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U052</accession>
    <name>A0AAD5U052_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006241</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000526">
        <property type="protein sequence ID" value="KAJ3215688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006150">
        <property type="entry name" value="Cys_repeat_1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00289">
        <property type="entry name" value="WR1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1832" mass="192065" checksum="0F24A3363117F64A" modified="2024-05-29" version="1">MTCSKASGNISVKQACGSDETCSNGKCNCKEVGSTKCTSQSIVATCSTGSGWTSQNCPTGTTCSGNDATSGLGGKCKCTKSVCTANGSLQTCSNGVLNAATTCEAGKTCITASDGSGSCKCTENTCDSNGNFVPCKEDGTFGPATPCDKDFTCTLSGGKRATCNCVPNKRRCSKSGNAVEGCRADGSYFDSTSCELAWVFGFKLQNTGGPAAFWAQIYVDGKLFDETGKVGNKFLLSETEPANKWNTDPNYDPQLELQKPTWTSGLTNLNGCPVTPVNKDLSWGAYQAQWYMNGKVVAPPAGIWLQDCKETSYNSYYNWARYILTASALNKISAGSHEIILNVAADNIFTIYLPDGTSETKSNWVNVYTYQVTLDPSTSSASCNNGICQSGCSPAGGSKCTDSTHVSTCAVGNVNWSPPSLCPTGTQCIGGDAKTGLGGTCKCTKNFCVNGQLQMCNSDGSFGALSSCGEKNCVASGNDASDQCKCVNPKCNESGQLIQCNSDGNFGTAKSCDAGFTCSIKSSKPAACLCDPSAKPKCDGNTVLTCKSDGTGYEKKPCSPSWVFAIEAYNYIYPQNSAGNPGAFWARIYVDDVLVDETGKVGNNFLVTNVQPDSTWKTDPTFSTVNWKSGLNAQNGCPVSSNPVTLPWGKSQDQWYDTKGAKVASPAGEFVLSSVAAGTHKVDIMLSVDNYYTIYLPNGKTYSKYADLAGATKYNWQIIDTYTMYIDAAASKSTCSDGSCICGGTLTCIAESTKCNPDKSDSLLTCQNGNSWITSDCPVGNTCKEGKCVCKTPGDSCSEDNSSVVSCDNNTGKLTKKQCGSDQTCSNGKCVCSPAGYKCKDDFSSVSCDGKAESWSAPKTCDTGKVCDSTTPLAGQCKCKTNQCEGQKIRTCNSDGTFSTAVACPTSGDTCQGGNNALIPGKCRCAEGATKCGGDGVTVLRCSCDGIWETSKTCSSGYTCTSGQCTCSGGSKCVNGESTKEYSCVAGIDLDWKPKDCSVGTTCLGNGSNGLGGSCKCTHDQCVGDKLQRCNKSSGVFETASTCPNHSDNTPVKCSGGDSSTDAVCKCAPVGTKCDTGGASWTTSTCPSGKKCSGDINGLGGNCDGGVCTQDTCDGENALTSRSLPQKYVLTTLSVKEVVQQQIRQNANVQRIVKSVEACKSDGTAWVVASEQCAADQTCNLGSCVCSPAGSTRCNSNTEVGTCVAGNVNWGKTACDDGKKCITTDLGGSCKCVQDKCDASGKIVKCQGDGNYGTAMSCEAGFSCKGDGTANNPATCKCTAGATRCDVTNKIVETCNSAGNAFVSTSCNADQLCSKGVCVCDKEGSKCINLETQAVCKSGKSNWESQKCKIGEQCTGDSNGYGGKCNCTKDKCLGVKIQVCTIDVSGIGSIGEPKECGPYLQCTSTADGDRCRCNPGETHCYNGYQYTCDASGLISNPVNCPTGTSCLTNDVNTGFGSCKCTKNFCDGSGKLHVCNSDGTLSITSCADDKVCQNEIDGSGTCKCTKDKCVQNGGAVAKCNSGGDFDQPSECAVGFACAYDPSHPATCKCKPGDKRCAYDNSEKCDADGNRFSVTSCPKSWLFAFELFNEENVAAFWAQIYVDDVLLDYTGNKGSKFGITATKPEDSWMKDPSFSTASWHYGLYNLENCPKSPIDPSQPWGSNQDAWGTNSPPPGIWYPSCTYDAKYTQNWARYLLTTDQISSGDHEVKLKVSVDNHYKLYLPDGTVQIKPSDKGLLKYNWQIVDTYIINVHNGNDAGSPPLCENGNCLSASTVSCISGKTKCSPDVIDGVMTCSNQNVWVASSTCPAGKKCDNGKCVCKNPGKSCVTSGIIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U097</accession>
    <name>A0AAD5U097_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SRP54-type proteins GTP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_006150</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000512">
        <property type="protein sequence ID" value="KAJ3215905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U097"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17876">
        <property type="entry name" value="SRalpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000188">
        <property type="entry name" value="signal recognition particle receptor subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF1">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="9">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="141"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="567" mass="63239" checksum="52926C89594FD085" modified="2024-05-29" version="1">MIDSCTILANGGKVLFEYKSGLNVPDLINDFVEFTLTNQSTNAKNSQINLKNNVLMYRQNNKFNYTIILSHQNIISIPYSNSLLAEFDRIVEVNIENLNQSILSSTFLNLVRKFEDTDLESKRNKAPRSFKETDKYLKSQLVSKESEEKRVMKGYSPKSKSDAEKSPKTAKKSTKQARTWSGDNMKDNNKSIKALDYSKDSTVDRNDEAIDANSLIDQNGIGKFNSEGLYEASELETPLMNSEESESSGFLSYFQNLTSQRVLKEEDLAPVLETLRNHLIDRNVAVDITGVLSESILKALVGKKIGTFSRVHTIVSTQMEQSIKKILTPSTATDVLRDINFVNKTENRPYSLVFVGVNGVGKSTNLSKVCFWLLQNKKKILVAACDTFRSGAVEQLRVHVRNLTSLCENLNLVGKVELFEKGYGKDSATIARDAISFAKNNEFDVVLVDTAGRMQDNEPLMRALAKLVTMNDPDKIVFVGEALVGNEAVDQLSKFNRALKDFSGLERPRQIDGIILTKFDTVDEKVGAALSMTYVTGKPVLFVGTGQTYTDLKKLNIKSIVCSLLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0B6</accession>
    <name>A0AAD5U0B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000345">
        <property type="protein sequence ID" value="KAJ3219252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0B6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF3">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042256047" description="Thioredoxin domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="48"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3219252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="30172" checksum="4DCB91328A13375A" modified="2024-05-29" version="1">MKLPTLTTLLFCSFVFSKQSKNVDALTRELLSIEADKEIQFIPTNSQAIDEFVEYGLKIIFFGANHCQFTQRFTPKFLETVKILEKENISNSALYYFDMRKVECSINFEVCEKLKIVGFPTTLIYVNGELKEEYPFEDEIRPFVKYIKKEIKEFKLAGLKNEIKYQVNSTLHQAPPPIIDYVDTDAVNQNSANNKLVEQVTIDKQIVDEQKGNEENKIMTERLNKAFFSVESTHAETENHVHHVDEQEEFSIYTLKTGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0H0</accession>
    <name>A0AAD5U0H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004241</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000296">
        <property type="protein sequence ID" value="KAJ3220503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0H0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051453">
        <property type="entry name" value="MBL_Glyoxalase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46233">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE GLOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46233:SF3">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE GLOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="5"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="197"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3220503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="428" mass="48142" checksum="FA5D35261981906A" modified="2024-05-29" version="1">MISEVEAYKAKGNLAFQAGKFEQAVAEYTKGIEFLKSNKRPTSIMNTMYNFISLQENIEKSIPPPSVKNQLLAVLYSNRSAANLSKKSLIEASLDAQQAINLNPSEVKYIYRLAEVKFQQNLYHESLKLFIQCSELMPKDHISYSNIIEKITLINFTLKDMDSGLKILQISPGKDICFKTLLAPIQSAIFDYAIQMKNFIYFISHRASKQALIVDACWDIDGILKFATENDVEIVGAILTHYHVDHAGGIPPPPFDKYGIRVDGLAKLLKKLPHIKVFINEHEIPQVIAGNPDISQKQIVPTTDGFEVSLPLEIKPKNHRHSFSPMIRQNTATRRNTLNSPLNFQQRIPIKFIHTPGHSRGSQCILVNNNRLFTGDTMFIGSCGRVVLPGHAYGGKFTTIQWERESGILSIEAFGVQLIIRGPNSYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0H8</accession>
    <name>A0AAD5U0H8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006247</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000528">
        <property type="protein sequence ID" value="KAJ3215659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0H8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.70:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_eL21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="18222" checksum="57AB2AC4FE6AD445" modified="2024-05-29" version="1">MPHSFGLRARTRHLFSRNFREKGSIPLSTYLKTYKVGDIVDIKVNGAIHKGMPHKYYQGKTGVIYNVTKSSVGVIFHKVVGNRYLEKRVNVRIEHIKHSKCRENFVKRVKENAEKKRDAKAKGVSINVKRQPLGPRPAHYVSTKNNLPTTVSPVAYEALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Y5</accession>
    <name>A0AAD5U0Y5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycine-rich RNA-binding protein 4, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RBG4</name>
        <name evidence="5" type="ORF">HK099_004063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000279">
        <property type="protein sequence ID" value="KAJ3220713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Y5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="3"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="133" mass="14666" checksum="9F92F97F28C554B4" modified="2024-05-29" version="1">MTSKVFVGNLSWNTNEESLRSHFSQYGDVTDAVVLTDRETGRSRGFGFVTFSSSEEAEKAVQEMNEQELDGRQIRVNLANERSDRGDRNDGNRDGSRGRGGFNGGARGGRGGSYGGGRGGYNNNRDNNRDRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U118</accession>
    <name>A0AAD5U118_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004129</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000284">
        <property type="protein sequence ID" value="KAJ3220649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U118"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF91">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="642"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="136"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="669" mass="75901" checksum="B4A049958E24E088" modified="2024-05-29" version="1">MSNDQTNWKKLSRGDLYVLFSQRISLFSPKEDMNQKFANQVITVLLTMNNMNGFYFGGFIFCILVDFIIFVLYFIRRGYEKKKSRQIKKKNFSFSSSKECKIKKTEELDYDELKNDATLVDLFVKESNNVKICMKFDFENLYFERKGKTILNNITGSIRPARLTAIMGPSGAGKTTFMDVLMGKLNRTKGNLYLNSLETEIYHYRKLIGFVPQEDIMLRELTVYENILHSARVRLPSSWKNNEIEKQVKKVIQSLELEQITHQKIGCDESSSGISGGQRKRVNIAMELAAIPFSLFLDEPTSGLDSTSALNICQILKKLTGYGQTILCVIHQFPLHINPADVLIDALSKGAANNEMLVEKWNEFYTVESKKEKELSSEDNERVKIENELFYSCVGKILSKRGAHWIQQFLWCVKRCILQQYRSISSLIFEVIVALSAGTLIVLKTGISATSANGELYKGIYVDPYTVISPAPAQTALPLYGLLTGFAVALSSSPAGVKVFSEEKPLFWRETASGHNSLAYYLGKTIGCSPRFILSSLHYSAFYQYFAAPTFPNFGMGYMIVLMTFFGVYGMCAFVSSLVNKKNANLSEASKWGLLFMWEISFNKWGTEALFSSSVTPMSSVYKVDDIADFFGYSLNQEYTDLGMMLLIGVVFRVFSYFGLIFINRNKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1C9</accession>
    <name>A0AAD5U1C9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000707">
        <property type="protein sequence ID" value="KAJ3213461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1C9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="289" mass="33414" checksum="6DB2BED30582CC97" modified="2024-05-29" version="1">MTIYCVWIYNNSAEDELPSYCLREGFYNNRYVSQAWLILSFGIPLFSTFLGVSIIFFVLKIQKIKKFFLNTQFQKKSNINNFKLQKKIKYDLACFLLIWLTLSWSGGFLLSLNQLNGVYFSYSQNLMSSHYIYLVIQEFSFFFTTTEFFFFFLFLEKIKLLVNLGVGLLECSKMEATPNSYYTDPYSPATTSSNKKLSIDSIKSLESFKVKKPFNLSFKIVHNGLFEEEDIEVGESSLMDINRHIKMKCVSNEHLGSFASSLNQDSKNNDLSSSYHLASDENLLNSNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1M5</accession>
    <name>A0AAD5U1M5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Telomerase reverse transcriptase</fullName>
            <ecNumber evidence="2 13">2.7.7.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Telomerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_007127</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.49"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Chromosome</location>
            <location evidence="13">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the reverse transcriptase family. Telomerase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="2 13"/>
    <dbReference type="EMBL" id="JADGJW010000667">
        <property type="protein sequence ID" value="KAJ3213899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1M5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000333">
        <property type="term" value="C:telomerase catalytic core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003720">
        <property type="term" value="F:telomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021891">
        <property type="entry name" value="Telomerase_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003545">
        <property type="entry name" value="Telomerase_RT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049915">
        <property type="entry name" value="TERT_TEN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066:SF0">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12009">
        <property type="entry name" value="Telomerase_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11474">
        <property type="entry name" value="TEN_TERT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00975">
        <property type="entry name" value="Telomerase_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="9 13" id="KW-0779">Telomere</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="14">
        <location>
            <begin position="390"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3213899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="579" mass="67744" checksum="3344057BDBF0A2F8" modified="2024-05-29" version="1">MYFEKTWTLLDFLTNCPVSASQPSNVCLKSKFYSENDDPKYIYFLKTTIVGINDTSKFEFPNLSLDVHYKQKEIVDKVIGILQNERVDNYVHNMLGVENVAPSSIVNLVKSKLWELLLSRIGQAAMIFLLTKVYLFIAVENGCFLQVTGTALYELKDGEAKEASVGNMETDILNKPPAEILSFVFSSSVEKKKKLRAKWRFKKSLKLINDIVSLKKKCHFRAILDFHCPKLYTHVEEQSEMLKFQTPYHQVWMFLKSVLDHLVPKEFWGSKENKMLVLESVKKFIKMTKFESISINQLLCGIKISNCSWVFPSKKNHISTSNFEKGREMMGSFLFFLFDSIILPLIKGHFYVTESSSHKHRLFYFRNDVWELLLQPTVEKLTRFNLKLIGKKNNFTNVPEVEPSNIRFLPKEKGFRPIINLGRKVVDNRNNNEFLMGASCLGLTDIYKKFQEFKAKRNSLQKFDEKFYFVKIDVKQAFDSINQNLLLKIVYDIIKEEEYVIQRYAMLYKNGERVHRNFMKKALPTIEQKPFSIMAKQLAQKLKNAILIDQIFYKYEKSGNIKEILSSHIERNLVKVHHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1P3</accession>
    <name>A0AAD5U1P3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rhomboid-type serine protease</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_003431</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010000225">
        <property type="protein sequence ID" value="KAJ3221519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1P3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="393"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="591"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="492"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3221519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="618" mass="68685" checksum="174017A987903946" modified="2024-05-29" version="1">MNYPAEKKVGDKALSTSTEDWLNSSNSTVPLNKSMPVNSNSRNQISCKTDDAKDFQNNNTSLKNLSNSINNCESRSNTSSSNLPFIPSTIPSKVNPQNLPTVQKKFKFEKQGNVECSKNTSNITTTPSVHNWKLEVSNPLNNINASDNELIQDSKKNYFIVNLAEGTENSNKMVNFVASDANAERDNSLLISVKAENSSPIEINMLSQDPARSLVPNIINKSVSKASDISMIGKKPFDTKKSAISVHSSRRSSAANSRRSSMGGKRRTVLNAPEGISLIYSEGVNGANDENVQNREDIENLDYYFYSNPNSVYDLLDTSEEGNLLPKNHETSIVVENDACEDIESAIKKRVTINRVEPLGGKRDIIDEKNKEFGKSALKKPKNRTKKNKIAKLPWFLIITTVVQVFVLGFSLYINYRNTGYVFEKIEKNYLIGPSTGALVQLGSRFSPCIKPLDGLDINEKIECFYGMYKFNETCSIEEICGLNGFNGGPPNQFWRFFTAIYLHGGLIHLLFNLGLQINVGFQLERIMGWWRMAILYWTCGVCVNIGGFIFSGIFTGISPAVGCSGSLYGLIACVLLELFQNWQIAVKPWLKFFITIVQILVALLIGMFPGGNSKCDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1R5</accession>
    <name>A0AAD5U1R5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ARPC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000413">
        <property type="protein sequence ID" value="KAJ3217730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1R5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3217730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="16630" checksum="E86134758DFE8D50" modified="2024-05-29" version="1">MNSGLRKKNVEIENSDDEEELRKSVGANNLELENQLRERQNKVQSSLSRGDLSQALKHVLENPPLGNCDLSLKEKNLSLVLSVLTTAKPSDIPIDSNWDLETLAKYIYKGMEHPDKFNPQNLLLWHEKVTEIGGVGLLGRVLTDIRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U281</accession>
    <name>A0AAD5U281_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000325">
        <property type="protein sequence ID" value="KAJ3219813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U281"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="94" mass="10876" checksum="7EF351D10FEBC984" modified="2024-05-29" version="1" fragment="single">IKTLITEIVIKLNLQLFSIPIGLQEEERQQLIWEREVIKKNLKETAKVVRSAQSITRKPSNRGSRSCGALLGYAPRKNQCERHTLRYNHSTIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2A7</accession>
    <name>A0AAD5U2A7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000212">
        <property type="protein sequence ID" value="KAJ3221736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="28"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="279" mass="31506" checksum="8AE62A9980079A1E" modified="2024-05-29" version="1">MAALFKLFFVRPNGTSVGSYDFSAKNPVSLNHVKIEMSAKTGYAHITNLSSSVGTLLNNTSLEVKTLLKNEDVFSLSGKNFRFEYTIESLEMQSKTKNPLTSTNTKKRKYHFDLVSSPKRLRSASRIKPTLVEVDKENTCPLPIQKSSGEKRNVRGKKKVHFSRYVEVKVFHSATLEDLSPTEVYRKSLKQTTLVELAPPITQKNSKKRKLVKEGREPAKDVLVATKAGLKRGRSQVKVDVKERTNTKVEQQRSEELKKVSTGTESCFSVNGRVLRKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2H4</accession>
    <name>A0AAD5U2H4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006421</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000551">
        <property type="protein sequence ID" value="KAJ3215332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2H4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="4">
        <location>
            <begin position="140"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="177"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="465" mass="54592" checksum="0F6B1315D351D5EC" modified="2024-05-29" version="1">MLPIANNFKNNLSNRQFKKFATLLFKCILILTVFSSVFNFFSNYASNKNKSKLSFQRIAFINGHQGTSDDITYLSQQLKFKFSEFNSRLTGGYGQTLQKANELNKQKLGDFFCSSFDYIIIGDTIPDARFLLQRLVMDIDRPCGDGDTGNSFCSGGQCCSKFGWCGDTIAHCSIKNCLNGCNMNELEFNVSPKCGTKKIIFLVTNRFDFAIPDKREYFNLILKTKKYFPEKIHWISNNPYENKYLEAFKERKELKYEAFQFLLIRPFGHSTLPETEIFPLEDRLKPVLIHQEHTENFTKILDEHQINYKLLPKKYGGPTALNQFKCFITIPYQVSTMKLYENINNGVVMLIPSRKYLIELMNLKPPMFDFSMLPQNLQSAEDKIFNFIDYYNDDLKKFFFYFDSIEDLKNILKNEMVSQNFEKGQRFDYGNLNLMNFPKIKDFEKFEWKKSRLESLEKWKKVLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2I3</accession>
    <name>A0AAD5U2I3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000178">
        <property type="protein sequence ID" value="KAJ3222381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2I3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052807">
        <property type="entry name" value="Mito_transl_resp_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46406">
        <property type="entry name" value="NITRIC OXIDE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46406:SF1">
        <property type="entry name" value="NITRIC OXIDE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="12"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="764" mass="88812" checksum="E94D1D99CB76D914" modified="2024-05-29" version="1">MNNYDVDLKKKKLSILNLPNEIIFLFAKHLDWKSVINFKSAGKKFYSIIELTNSQILDTLVHFQAVELWNCEKLDKQLRFFVSKLNWMDPHITVGLNLIPIVSKFGSIAGLTRIVTTHEHIQIPKAEWDPDDTNENALHLIIKLGYFDLLKILDFCEIINYYYQTIHLDIAAKFKKFDVFKYLYSRFNMSTSQIISPLLFDYDPIFLNYRLNFSVEDLDTTELLWACSEGYFEIVKVLLRDGTIDPSRNDNKAINRANNSNQFAIVKLLLSDIRCGSNFQSFNEMNPGFIDIAILEKKKKMLAENNENLNDLTTLTKPQLNKILKKKTELICKRCHSLKNDNSNRLFFKQSIPLKNIKIFEELQVTNKPLLYVYIVDALDFPSSFIKNISQTFNFNNNNSRLLIVFNKMDLVQFESKRNLRETKTTGFDKRYFINLLKMEEKFSNNFDYLKDVTFVSAKTGEGLFELIEKINEKIIFKDENENFLGCDVYFVGKTNVGKSNLLNALKKIGTGKEENTITTSNLPGTTVNVLKTPAIKFGNLFKSSKKGNKNFQANFYDTPGIKNEVSLTKFLVSKELKYLEPRQTLRPIGIRNFKETVFLGGLIRLDLLEAEYENQKFQSEFELLKNKKYYERVNHLNLIFFGSNLLKLNVCKTFKAEENYKNLVTENLVPPLNFGKSKEDRLKLLPDMNLVKEFEIKQTTTEEKEKEKLLSTDIHIANVGWICLYGNFSSAKFRLFSLGGIGCGLRKSYYLPKWDMKNQRYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2L6</accession>
    <name>A0AAD5U2L6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ACAA1</name>
        <name evidence="16" type="ORF">HK099_006318</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010000538">
        <property type="protein sequence ID" value="KAJ3215503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2L6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000010">
        <property type="entry name" value="Acetyl-CoA acetyltransferase (Thiolase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF8">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="14">
        <location>
            <begin position="26"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="15">
        <location>
            <begin position="289"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3215503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="411" mass="43015" checksum="00755A9B407E3D6D" modified="2024-05-29" version="1">MSNRVNQVAGHLAAHHQVGQKHPDDVVIVSALRTPMTRGKRGGFKDTHPEFLLAAVLKATVERTGIDPALIDDIQVGNVLPASGGATQARMAQLYAGFPETSSISTVNRQCSSGLQAVHYIASAIQNGTIDIGIGAGVESMTLSYGPSAMPPSYDDDISAFPAAADCLLPMGITSENVAKKFGVSREKQDSFSALSHKKAANAWKNGWFNEEVIPVTVTQVDKEGNEKKVTVKADDGIRPETTPESLAKLKPAFSKDGFTTAGNASQVSDGAAAVLLMKRSTAKKLNLPILGKFTAFATAGVPPNIMGVGPAYAIPKVLKKVGLNINQVDIYEINEAFASQAVYSVEKLGIDINKVNPKGGAIAMGHPLGATGARQVATLLTELRRTGKKIGVISMCIGSGMGAAAVLEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2W6</accession>
    <name>A0AAD5U2W6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006104</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000505">
        <property type="protein sequence ID" value="KAJ3215994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2W6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026243">
        <property type="entry name" value="HAUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31570:SF1">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25762">
        <property type="entry name" value="HAUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="82"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3215994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="28474" checksum="60202DCB83E0CE9F" modified="2024-05-29" version="1">MEEIVYKYKKEYETSTKQFEEELLLTEHFKKEENIFTDKILQTSDFSTKTDGQVLKTLIKIQSLLKLKDHTDTSFICALTRLESSEFKNKKELKRLAKLENNLDKSLAEMQDNLNLLKRTVSDCKGTKFEQESRMEEFEKNIEVLEQKKIEYREKLEFFENMLEDGELNKNRIANLQELELQLNNLNSLVNIREEKLKSFFDLKPDFNLSKIKFEEKVREFNSLVEKKDILIQNLSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U373</accession>
    <name>A0AAD5U373_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucosidase II subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_002056</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; N-glycan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000165">
        <property type="protein sequence ID" value="KAJ3222651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U373"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090599">
        <property type="term" value="F:alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06603">
        <property type="entry name" value="GH31_GANC_GANAB_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000039">
        <property type="entry name" value="Glucosidase, alpha neutral C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF54">
        <property type="entry name" value="BCDNA.GH04962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="12">
        <location>
            <begin position="73"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="11">
        <location>
            <begin position="352"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="13">
        <location>
            <begin position="688"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3222651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="927" mass="107878" checksum="6F5BBF660D673376" modified="2024-05-29" version="1">MLPAGYFTVKEHEFKKCRQSGFCVRQRAYSDLVDLKKEPTPYKILRETVSVQKDNGVLTCEVLNQLSNIKYNFKLEALENQTVRIRLEEKDPKKKQYASVGNFSLVEEPKSTPFKTYVKAKSETEFSILEFGKNAKMLLQENPLLLTLKVNEVSVFTFNEKGYLHYEHHREKATVKNSEEPALKNEDSPGMEEVLAEELSEKEKLEKELKEKLEFGMWEESFEGNTDSKKYGIPEHASSFNLKNTRGNDVAYSEPYRLYNFDVFEYILDSPMGLYGSIPFMMGHKKGNTVGMFWMNSAEMWVDIEREVELKTRAKQTVTHWSAESGILDLFVMLGPTPREVSSQYTSLTGKPALPQLFAIAYHQCRWNYNDEADVKEVNAKFDEYEIPYDVLWLDIEHTDGKKYFTWDEVKFPTPQEMQNNLAKTGRKMVTIIDPHLKKDDNYYVSKEAKALDLFVKNKDGGDFEGWCWPGNSQWLDYTDPKARKFWAEQFKFESYKGSTSSLYTWNDMNEPSVFSGPETTMPKDNIHYEGWEHRDVHNVYGMLQQRATFEGHLLRSSNLDRPFVLSRAFFLGTQRYGAIWTGDNFAKWDHMEASVPMLLTIGVSGVTFSGADVGGFFGNPDPLLLLRWYQLAAFQPFFRAHAHIDTKRREPWIFGEPYTTLIRNAIRSRYRILPYLYTLNFEANLHGWPVMRPMMYEFPEDYFVYDMGDQYMLGDTILVKAVVNETSPSVKVYLPQGKWYDYTEFNAIDRPKDGLINYDTPTDKIPIFLRGGSILTRRERMRRSSSLMKRDPYTFYIALDDLELASGKIYTDDGHTFNHLKGSYIYSEFEFKINGNSGKLSSKNLLVKEFGASKVTKNYFKNQDVDFGGRLERIVIFGFKKPNFKLVEVKVENKILSFKKEKNEVFVIKDPAVFIGEEWEISFKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3X0</accession>
    <name>A0AAD5U3X0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000196">
        <property type="protein sequence ID" value="KAJ3222017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3X0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10175">
        <property type="entry name" value="MPP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="167" mass="19722" checksum="F8DD80C5EF6105F4" modified="2024-05-29" version="1">MSDNTRDVHVKKLSSKIKSMKFMHKQEERLIRQRLEEDQKKEALEAEWVLFLPDNQLDKKFEFSKIVEIILLFVLSDFKVEYDTSFMSFSTSDISIGGRKSYRNFNKDIQKLNANTESNFKQTISRLRESADEVSNLNTTDFVKKRRNEKEEAINKNKKQKITTSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U446</accession>
    <name>A0AAD5U446_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002518</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000184">
        <property type="protein sequence ID" value="KAJ3222243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U446"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="290" mass="32851" checksum="45F98001C2AD75E1" modified="2024-05-29" version="1">MKSGSLANGWNFQKGTTNNQESTTEIFYKTSTSPQKGSLECECIIEEIGSNFEGGSLQGCTFKLTGLKGGFLFFNVNDLDQLFPLSNPYYNLKKSKISILKEFYLKLCTKSFLSSEIKCEKFDVTSTYFGNFNLPYQFFNFKFEEFNTKIDEFKEEIIRKNKFDEEQLDILPILPELNFSEDIAKAEGKGLLNWIFGTILDTKKEKPANGLNWPYWTSSDGKVTDLGILIKAKNDNNFKLNFKAITIDKFLGSNVCGGSVKKIGETVEENCKKVDIPCHNFGEIIALQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U463</accession>
    <name>A0AAD5U463_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Exosome complex component RRP45</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EXOSC9</name>
        <name evidence="9" type="ORF">HK099_000843</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U463"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11368">
        <property type="entry name" value="RNase_PH_RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033100">
        <property type="entry name" value="Rrp45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF14">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="30"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="183"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="271" mass="30225" checksum="0678299F5CA6249F" modified="2024-05-29" version="1">MNHQQKFINLALSESIRIDNRAVYDYRKVQFLFSENVSGQVQVNLGNTKILAKVSGEISRPTASNPHEGILQFNIDFSQMSDQKFESKFTERELNITMLLEKALKKSKAVDVEGLCLVAGKKVWSIRVDLRVLDNDGNITDCACIAAITSLLHFKRPEVTVQGDELTIHSTEDKHPIPLSIHHIPICTTFGFFDDGQYLVVDPCLVEEQTMESEMTVVMNVHREVCTISKSGGVPLEIDQILRCCQIGSIKAGEVTNLIRNAIHGVSPDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4C4</accession>
    <name>A0AAD5U4C4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Guanine nucleotide-binding protein alpha-16 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GPA1_7</name>
        <name evidence="13" type="ORF">HK099_003549</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. In the 1-cell embryo, probably together with goa-1, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisons, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000232">
        <property type="protein sequence ID" value="KAJ3221402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4C4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002307">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000002">
        <property type="entry name" value="guanine nucleotide-binding protein G(Q) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="170"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="195"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="264"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00059820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3221402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="348" mass="39373" checksum="9F31B89A976B35C5" modified="2024-05-29" version="1">MGCCLSAEEKEKKKRNDDIENQLKQEKLAEAKEVKMLLLGAGESGKSTILKQMKLIHDSGYSNEEKEAFKEIIFSNTVQSMRVILEAMGTMGIPLGNPSNESHQQVILDLPSQIEAEVFPAEVAAAVKSLWVDTGVQVCFNRAREYQLNDSATVDRIALPDYVPTDQDVLRSRVKTTGITESSFHIGDLTYKLYDVGGQRSERKKWIHCFENVTAIVFLVAISEYDQVLVEDETVNRMQESLTLFDSICNSRWFVKTSMILFLNKIDLFKIKLTKSPMGKYFPDYTGSDDFESASEYILNRFVALNQSDKKQVYTHFTCATDTSQIKFVMAAVNDIIIQSNLRDCGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4J5</accession>
    <name>A0AAD5U4J5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000105">
        <property type="protein sequence ID" value="KAJ3224097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4J5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020339">
        <property type="entry name" value="C20orf85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31909">
        <property type="entry name" value="CHROMOSOME 20 ORF85 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31909:SF3">
        <property type="entry name" value="SIMILAR TO PROTEIN C20ORF85 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14945">
        <property type="entry name" value="LLC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="194" mass="22276" checksum="D833E0D81211DFA7" modified="2024-05-29" version="1">MAEGGGIKHEKRIHNVVHDDAIWRQTINYELNTAKNWDKSWGFVCDAYKTHLDIPEKNSRLPPLKNKNYSQQPNASGLPSKLCPGLTKDANSLISDWLLTYDTPRIVNYRFPASKYTYPATTSNEVGWPWGRNSQYGNEEPAKKKIDNNDNQFQSKPTKNNFPPLYYTLERFGNHARGKQENLKWFGGSLEGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4L1</accession>
    <name>A0AAD5U4L1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">MCM7</name>
        <name evidence="14" type="ORF">HK099_003295</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000218">
        <property type="protein sequence ID" value="KAJ3221639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4L1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000004">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000288">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24901">
        <property type="entry name" value="WHD_MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="332"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3221639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="731" mass="82237" checksum="7F5AEB7A4F7A4885" modified="2024-05-29" version="1">MSFLHINYDEECAKIGRFIETFHDDQKKPKYVDYMKRVSKGKQDSILIELDDIKKFFPDDSIVESIEKNTRRYHTLFCRIIDPLIPESRNVINDESSPVEVMIAVRKQLDLDRENSGQTNDADNQQFPPELTRKYVLNFKPLSTQKPISVRNMLPSMLGGLVTLKGMVTRVSNVKPLATVLAMSCERCGSEMFQGVSSSSVMPLFDCQSNDCKRNNTRGKLVMQTRGSKFLKFQEVKVQELTEQVPMGHIPRSMSVHLYENLARSVNPGDSVTISGIFLPIPYVGFKAIRAGLLTDTFLEAHHIVRVKEQYNSMVITSDMRTKIEELARKDMYQKLSKSIAPEIWGHDDVKKALLLQLIGGSSKETHDGMKIRGDLNICLMGDPGVAKSQLLKHICKIAPRSAYTTGRGSSGVGLTASVIKDPVTDELVLEGGALVLADNGIACIDEFDKMDENDRTAIHEVMEQQTISISKAGITTTLNARTSILAAANPLYGRYNTDKKATENINLPAALLSRFDLLFLILDKPSIENDLRLAKHVSYVHIHNTHPPLDEANEDIVDIPLLKHCISLARTFSPVLPPEVGEYLVHTYIMMRERFEETSDFQYTSARTLLSIIRISTALARLRFSNFVAMADVDEAIRLNDVSKASLLNQGGAKKSDPMSIIYDTILQMSKNNVDGKFRLELKYGEILEKVKIKGFSEENLLDCIRENEENEIWILTGQGSKLKWLLIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4L5</accession>
    <name>A0AAD5U4L5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NEK8</name>
        <name evidence="10" type="ORF">HK099_003688</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000244">
        <property type="protein sequence ID" value="KAJ3221211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4L5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08215">
        <property type="entry name" value="STKc_Nek"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000262">
        <property type="entry name" value="Serine/threonine-protein kinase Nek8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="248" mass="27988" checksum="BDF6B9F030F64BDE" modified="2024-05-29" version="1">MTDEDRTTSVSEIQVLSMLRHPNIIAYYDSFIAKEGLEQKGSLHGTLMIVMEYADAGTLDDFIKLQKKSLPEEEILNMFSQICLGLHHVHSQNTLHRDLKTSNILISGTGRSKVLKIGDFGISKVMTNSVAKSLVGTPSYLSPELCEGKPYDDKSDIWALGCILYEMTMLRKIFEGTNLPSLVLKIMKGVYDPIPAHYSQDLRELIGWMCRLDPEKRPQMRDLVATSQLQQHLIEAQISIGRVDSMWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U503</accession>
    <name>A0AAD5U503_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Threonine/serine exporter-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004526</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000320">
        <property type="protein sequence ID" value="KAJ3219960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U503"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="3">
        <location>
            <begin position="48"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3219960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="439" mass="49170" checksum="FB853A94E8C08EE8" modified="2024-05-29" version="1" fragment="single">MADFLHSGKLSKRIISNSVVNNVEEIELAEVSFDDEDKSEERRILKQDFIVRLAKCLLRFGNTLYQAERKLRKVCLSLKIKAEFAGLPDLFLISFGSPHLTTVHTNNQTFLLFQRQGYDFGKLTEVTKLCHNLCKKVENSYDHEVKLTFPEAIKTLDDIELSKGSFDNKIFQTLSFGLGSAAVAQLAFSGSIIDICIAFFCGTFVGLFSLFVSVFLTEYSYLFELIASFFVTFFVTLFQTLFPTMCINFSCIFLSSLIVQLPGLPFTLAIMELCNRSTVTGTVKLAHSMIITLLLAVGVTMAKSIPFLLHDTSETCTLNFWSPGVPFYFLSLPLSSFTINYLLKVAYVDWIPMLVVNSSGFFSFYICINHYQMKVEPSSAITAFTIGLLGNLYGRFSKDRLAITFLSGVKGSLAILNDGDYAKGAIFTSQMLLNSIWIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5E9</accession>
    <name>A0AAD5U5E9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-activated protein kinase glycogen-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007443</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CRP1/MDG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000072">
        <property type="protein sequence ID" value="KAJ3225068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5E9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF81">
        <property type="entry name" value="CRUCIFORM DNA-RECOGNIZING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-activated protein kinase glycogen-binding" evidence="3">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="262" mass="29535" checksum="F72F16B3FF09F67A" modified="2024-05-29" version="1">MLIKYYDLSKSANEVIVTGSFDNWAKTVAMNYIGDHLFTANLTRLENGSKLLFKFVVDGKWTVANEYPTESDGQGNFNNTLIVSDRENENLTENKILKETSPLVDSFTPSTEGLSTCNLSAEKKEVNDDKVISKKDEMKEILKNVEGIKSAEVTQSDDSVKQPNKLLNKDSTKTLNKDNEVVEEKPKFFQKLTLKKSNRNLGAKKNLDANHVNKVENGEVLLVNNVEEHSDEKNGKRTGKSGPFWKNIFKKNKGEDLLNENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5L3</accession>
    <name>A0AAD5U5L3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Gamma-aminobutyric acid type B receptor subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GABBR2_2</name>
        <name evidence="13" type="ORF">HK099_007201</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000068">
        <property type="protein sequence ID" value="KAJ3225189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22673">
        <property type="entry name" value="MCP-like_PDC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="983"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1017"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1051"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1090"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1140"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1172"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1208"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="981"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1358"/>
            <end position="1380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3225189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1380" mass="156008" checksum="781EEB7065643566" modified="2024-05-29" version="1">MLNESKFLKESFSLSTISSELLEKLFNLTKKNMKEIYDNTNDSKWIDNEKWREFKEENPLYLCIFDKDDNNKLVAFCYYQITYEEDEKVIYCYELQVVKRYQNEGLGKFLMSELEKLSKELKLNIVLTVFKNNFVALNFYKSLGFEIHHSCPTMFRIPIMIMVIMQTFLVSLLILIIPLILSLISINESNSTGIRTSEEISRNLAQQLQSKQMDNALLNIDKYFLGVETFVTIVNITFLASETEFDNYDVLYRTFLKMHEKFAPIQAVYFAQESDKNFIGIKCLNYTDPLKNLVYMQSFTSSPTKPCRTCKPFNETKSKVIGYYPIDVFGTGYPTITNISTTSERIYDAFGRKWFINSSKYSKFNASLLWTDVYRSTSGELDITVSYPFFNKFGNLSGVFGVDITLDELSHSIRNMVGTPNGFVYILSQNGELIVSSGLEPIYNSFNNKSIRPSEMKNSYLKTTGLFLENLITGGNTSAVINYNLLNLEDNNTAIFEVNDIFFQVKKVPKRIPIMYLVNGGPREDYVGEIDTIQTKLENELQFSEMQTSCIVMIRNFAQLLDSKKFGVMGSGIGNSDKLSYQIGGSSSNGGVQPDKSQSYSEVGVHEALKLAVEDINKHLSDFNLAEVNFTLKYFNTNYSSAISVKQALAMKKEETAASPIIGVVGGFYSSHSKALSFATQSLYYILLSLLLFNDFRNLLQCSGSSTSPELKDKGTYSNFFRTVPNDNFQSVAMANYVYNNNWRRVAIINAQVFQATASELGITVVTQYIYSQAKPNYAEMAKAIKFSGARIIMMFAYEDLILYFREARKLGLLGPDYGKNTKYKLIITILVYIGSDGTWDMLEYLQLGKLAPPEGYVAEDWENLNGFFGFSPKDYSDTAVFNDVEPSDLSTPKMTLSNLFDKKFTSMSGEFSLDKNGEPIQTEYQVENYVGNLTRVIVSSIDGRTGILVPTDVKPLYFGGSDKVPLDSAGEMKVSLGDAGPLIIFIYFMLNLAITFASICYLIYKRDDPLVKRLSLPFLIVISIGLMLVWVSIFGYSGKMTETVCNFQTWSMWLAFSIVMGALLIKVYRIWKIFDNVKMERRNLSNTKMLLNTFLIVLIESVILICWQAIDPPIPQKIMKADFYYYDCLSSNKDNQLNFNVALIVYNGLLLLIVTYVAFKTRNIDSVYRESAWIAQLSMNITLCSSITVVIMFISENSLVSKFYIRMIAIGFSTSVTYFCLIGRIVLVLMMSNKGITVAKNTQSLINTGTTFKKSNVDKKGYQFENSVIIKEEGILTTWKKGQLFVHTGLPRMISIVSQTKKCGFTLILKDAIIENGAVEDSIKILCGRNFLIQCKDADQCNTLLAQLKDDTVGKDVEPRASAGQTGVASFGKASDAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5S8</accession>
    <name>A0AAD5U5S8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Potassium channel tetramerisation-type BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000061">
        <property type="protein sequence ID" value="KAJ3225447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5S8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499:SF136">
        <property type="entry name" value="GH08630P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499">
        <property type="entry name" value="POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Potassium channel tetramerisation-type BTB" evidence="2">
        <location>
            <begin position="323"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="474" mass="52489" checksum="64796EB37045E813" modified="2024-05-29" version="1">MSTISALPVEESSSSSQSNSAKPKTNKKSWLTWSQEVLTDSLVETAILLKKSPIPSAVTLAGEATNEGYRKLDEAADINSKLQGIGSSVIKQGIIATGVVGSALLKAGVAYQRAPGYSDDKEDEIHYSSVNRVKWVKLNPFPGGFPKPDMLDMATQTVEEEQIGEEQPGGIRGYVAKAALLAGNYTHSYLAPTSSTNFNRSLKSKESADLLVNKQSSEQLKTKPSLEQVLSAPSSLTEQQKLKHKASKLSMRKMASVDSMSSFTSASTQIPNNINHNNNLKNLCTICGAKSLIYNNQLSDLEDELFFPSFESISSPFVDKILVHLNVGGLYIDTTLETLTCVKDSLLYDMFNGIAIKERDDLYEENSIGISNDIQDNMNEFENFNSKTPPIGPDGRFFLDRDGSLFHHILNNLRNTNQNNDDTLETLPTSKKALWSLVSEAKYFKLKNFEIQVRKKIIKIRFEENFVFPLADFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5V6</accession>
    <name>A0AAD5U5V6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription elongation factor Eaf N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000059">
        <property type="protein sequence ID" value="KAJ3225506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5V6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019194">
        <property type="entry name" value="Tscrpt_elong_fac_Eaf_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09816">
        <property type="entry name" value="EAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription elongation factor Eaf N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="318" mass="36151" checksum="9A5DE7BB310111E9" modified="2024-05-29" version="1">MELKASQNYELKIGSSFEKNSETEESLSYHTFNYKVRPDSFLSNLKDGDLNSPKNNDYYNLRLNDPDGNFLESLRNQVECVLIFDQKTETFTLERVSSVFKLQQQNKQTKRLKSFSIPAKETKEVVEEGSYEENIEEKFTPEEENKPTPEEMVEDDEELDLDKLLDGILTESENENDATTVLSEEPSTQKLVEDEEATVAENAEKETEVEVDADGDDMGFLDDDLDFEIPVEDSNQNEKNSEKEEVADNMQETRRKDSFNDSMEEDFEVSSAVRSPAPNDNKIEDKPLSPPKKKKPITLGALLGDKSESESDSGSESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U606</accession>
    <name>A0AAD5U606_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KIF24</name>
        <name evidence="10" type="ORF">HK099_006338</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-13 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U606"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01367">
        <property type="entry name" value="KISc_KIF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000012">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF20">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="226"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="44"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="519"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="611"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="524"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="316"/>
            <end position="323"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3225725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="740" mass="83483" checksum="0976205E98999EBB" modified="2024-05-29" version="1">MFLKISSCLSGYGVNSVEKLINLTMQDYSAVGIVSMEDRKRDYPGLGEHQYKQPDSKSFLPKPTTLFGKSQYQPQQQNLSSQQQQSISIPSLSDQLSRVEVSERSLKNQSQYSYNNNSSEDSLDLSHTEQPQQQFQNTSVSIKQKNKPRSQNHANTTTTPQVQSQQEQEKLFKQNSFPDIVDETLINKKQFNNKRTAVLNAYGIPLANTSNQPVSKGKSQRDLMDRIRVCVRKRPLSKKELKRNETDIATVHSRRSLTINEPKVKVDLTKFIEQHNFVFDEVFDCNCTNEDVYKRTALPLVEYIFTGGKATCFAYGQTGSGKTFTMLDTTHGLYAMAGRDIFALLAQPENKNLAAWVSFYEIYQGHLYDLLNSRKRLFAREDGNKQVQISGLQEVEVTSEKELIKVFDTGSGTRSTGVTGANADSSRSHAIFQIVLKNKTGKSKIKGKFSFIDLAGSERGADRGESDRQTRMEGSEINKSLLALKECIRALDLDSKHTPFRQSKLTQVLKDSFIGVKELKSDDQENEENDDVLSDSHYCEENDEQDDGDADEVFSDPDDLLQEYPPESLASIGDDFVSNTSEDEDDNLDLLEPIVADTILKPKLFSTGSSPKLNKASNISNSKQGMERSGSFNKKKHISPKLNNPKNLSKDDVSLNIDNAIDELVKTHKLLIKEFENFSRKEKNMLVEFATQVEVGSGCLSESNYDGIKEYLNNVNFILDEKSLKIDKMKLAIEKIKEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6E4</accession>
    <name>A0AAD5U6E4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Basic helix-loop-helix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CBF1</name>
        <name evidence="4" type="ORF">HK099_005416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6E4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787:SF1">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="98"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="214" mass="24718" checksum="EEED24C094728BB1" modified="2024-05-29" version="1">MYSEQHLTVPSSIQTFIDSKTLLLDLMDSFQVVSEGMYASNSEFPSFYNQQRPTNTYSQQNDTSTHSTNSSNSISQLQSTILPTTQKLTVGSEEWLKVRRENHKQVERRRRETINEGISELAKLLPEGNKADTERNKGRVLQRTVEYINNLKEQVIQTQQRLELEKLLCEQAVQELVNQLATLKKENLVLLQERQEREQVDKSGTEDSNIDEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6H3</accession>
    <name>A0AAD5U6H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007978</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NEMF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000083">
        <property type="protein sequence ID" value="KAJ3224729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6H3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.310.10:FF:000001">
        <property type="entry name" value="Nuclear export mediator factor Nemf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.310.10">
        <property type="entry name" value="ibrinogen binding protein from staphylococcus aureus domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021846">
        <property type="entry name" value="NFACT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11923">
        <property type="entry name" value="NFACT-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="8">
        <location>
            <begin position="571"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="NFACT protein C-terminal" evidence="9">
        <location>
            <begin position="1047"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="723"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="786"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="844"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="980"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="723"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="738"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="793"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="874"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="927"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="980"/>
            <end position="1003"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1201" mass="137924" checksum="6BCC0316CF9EE3E7" modified="2024-05-29" version="1">MKNRFSSIDTTSISSTLKQNLVGLRLQNVYDINLKTYLFKFNSQNDKQILLVEAGIRIHTTIFTRDKNNTPSQFCQKLRKHLKNKRLDNVNQIGQDRIIDFTFGTGDNAYHLIFEFYSSGNIILTDHDYKIMAVLRIVELEYKDSSQKKYTGTTKFQIGEMYNLALAQKHQGITMEKLIETLNYKPPIKESIEDELVITKNPKKHKKFRTNVEDIKKLQPLRKFLRQAFGPSYGNPIVEHCLLKSDLDANLLYPEQFNLDCDSDYMHSLLVLLKNADKLIEEISQNPKTKGYVFYKLKENKNEPSGDINEINPLPLSEEALAVSTNYIYTDFQPFLFEQLKELPYLEFNSFDEAVDDYYSKNESQKQLLQAEQAQLQAQKKLNQVRQGHENQVSSFDEVKRKRELQAQAILDNLENVDSLILTIKGLLSQGMDWVDLSELIKEEQRNGNKIAQLVVKLKLEAGQVTIKLRTSEPNEANFDINSESDDDAEEETENNYAEVDIDIFQTAYANASKLFQDKKIASMKQAKTMQTSKKVVKLAEKKILANLDKADHKKNSSTISKNRKPYWFEKFLWFISTENYLVLGGRDTAQNEILIKKYLSKGDIFVYADLEGAAPVIVKNIITSNNELNLQPPPSTPEQPVPPQTLLQAGTMSICQSKAWDSKIITSAWWVKDDQVTRESSVGDSILNGSFAVRGKKNWLPPVSLIYGFGILFKVDEESAARHHTERRPWARDIEQDTMSENKSSSILDLESGGELSFNSGVEENEEKEISVKSFDKCEKKEEIADFNSEKEDVEEGSEEDFSDDEDFEYPDTKISMTKEIFDSKSISSSLATSTADKYNLDEIEPEDKKNSEILNSLMEKPTSKTLTKKVLSAKERRDLKKAQKKSGLNVVEKETKSETANVTMPKEKKEEENSILKQRPPTAVRGKKGKQKKIKEKYGEQDEEEKNLMMEIFSPNKGPQPKGKKEKKLLKEALLKQEEEKKKAQRIEDSKNKKIQEEKSKNLSTSHDGDDNGENDEINEEKNRELKNKLLLEEQEKIDQEINDTFTALNTLTGQPHFEDTIHFAIPVCAPWQSLQKFKYKVKLLPGSLKKGKAAKTAQHFFLNEFLYEKDISNNKKNINIIKKNNILEKINNNNNNNTDDDNEKIEEFEASDIYYNSQKREIEMIKLITDNEFIIQILGKVKVVGGNNVIENKKKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6R0</accession>
    <name>A0AAD5U6R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 9A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PDE9A_3</name>
        <name evidence="5" type="ORF">HK099_007390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000071">
        <property type="protein sequence ID" value="KAJ3225103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6R0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="4">
        <location>
            <begin position="267"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="85"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="435" mass="50328" checksum="99FC0526977B9AAB" modified="2024-05-29" version="1">MSKVIYIKVENNEELQSVLIPTGAREDEIKESFLALADLNNFNSKNVVLRLFQKEGGLIAIGPNLPQNTQQSSYNLEVEKMVDVNRLIEDENFNYDEEAEAVEKQLEVVMKKPVNFADVKEIRDSVINLKNQILELENAGILNSKFLPHNTFASKEKKNLVKKHFSTEVKYIFTEETKENLKRPQFDNWQWEENEIMSLLEFIFTDLGLMEDFNIDRKVLKRFLCAVKDNYHENMYGIINVTGLVHRLKPIDKLILTVSCIGHAMLFTILKLNETNILKNVPDSVYRDVRKGIIKCILSTDMVKHGEIMGQFKKIVDNFNYDDVEHKTMLLQMITKCADISNEEPWVDCLLEEFFTQSDREKAEGLPSAPFMDREKVTKSSAQIGFIGFVMIPLFEMVGKLLPLLDDNVILPIRRSLAYYKEMQEKMSNMNSTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7S1</accession>
    <name>A0AAD5U7S1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">adenine phosphoribosyltransferase</fullName>
            <ecNumber evidence="6">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">APT1</name>
        <name evidence="12" type="ORF">HK099_008288</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7S1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002055">
        <property type="term" value="F:adenine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000021">
        <property type="entry name" value="Adenine phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002634">
        <property type="entry name" value="PRK02304.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002636">
        <property type="entry name" value="PRK02304.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF3">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="11">
        <location>
            <begin position="39"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3227878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="179" mass="19418" checksum="B60D1DCD8CFFF50F" modified="2024-05-29" version="1">MSSQKDIELIKSKIKIIPDFPQKGIMFQDIFPVFKDPLAVEALVTHITSHILSTQLKKVDAIVGLDARGFLIGPIIAMRLGCAFVPVRKRGKLPGGTVQVAYQKEYGTDYFEMQDDAISAGQNVIILDDLIATGGSAKAAGDLVGKMGGSVLEYIFFIELTFLNGAKLLNAPVYSLIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U846</accession>
    <name>A0AAD5U846_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U846"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1480.30">
        <property type="entry name" value="Designed four-helix bundle protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052993">
        <property type="entry name" value="CFA-57"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="8"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="273" mass="32219" checksum="B36802084B5204E1" modified="2024-05-29" version="1">MHERDELIQDKEKRVYDLKKKNQELEKYKFVLDYNIKYLKQQVEPRENHIAEMTNHIQDINQDLESLNKSKSFSELKIEKLNEKLKKTKQDYTKKHQKVQDLFHYLKGFKTDFQDLMKYIQEPAMLKKATENLNKKYCSEMKGFKNNLLDPDVKKENLRHQELLKSKIQDLSVNSDSILLTFRADDIHTMTTNQSLLNEINELRNINKHKPLYKNKIIKLKNKLSEVESEENQGSNYRPSSSNVGKLPLIRGMSSPLPPVPTFQRSKIQLGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U873</accession>
    <name>A0AAD5U873_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anaphase-promoting complex subunit Hcn1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HCN1_1</name>
        <name evidence="2" type="ORF">HK099_005256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U873"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="34"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="671" mass="75842" checksum="42CC11152D987823" modified="2024-05-29" version="1">MEILRSDSNQKLPEYQEPNSIMTELVELLKEVMVFQTLGRESSEFIDYIKELVHFRYYKLGDTVCREGESAKAMFFIIRGQVSVISEAEDITFAELNAPGFFGEIGAIFNVNRTATVRASTKCVLAVLLAEHLEATSQKYPEIHQAIKEQAETRFKDLFCEMNKSGRKLKNDTEERYVEMKRDISSGSLKEFKIARGSSRRNSELMLPPSPVDDHFKVGFTSNSLESICESGKLSKSEDILQIYSSKGALTDKHFDGLSYSVPSSPLCSFPSSATWDANNDVEISEQDDKLHKQLIQHPPQLQPNNTMKTLLKHGGLGPRRASVAVWSDDKLTQFAQNIQNKIKKESNLSTASTKLEETTLTTEIESNEMQVLKLVLKILPFQIVLHLRLISKAINNHIQLIPIYDLELSSFHKKINDTTLSSILTSFGTNLKKLNLKGCWSVTDKGLQAIANNCKDLQLLNLHSCWDCTDLGLVTLTNSCNNLVQVDLSNCRKLTDAGVLNLLSKCFNLREIELSYCKNLTQKIFDHQSWTRMKKINLQRCTAISDQAFERWNKLVEGKESSIDEISVSEENKEPEIRYHFDLNDLNLSDCSFLTDVAIEKFSNICPNLITINLSFCCGLTEKSVSHLINFCLKIKNFDLSFCGNACTDEILLAISKSLIFLERLAIRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9M4</accession>
    <name>A0AAD5U9M4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras protein-specific guanine nucleotide-releasing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RASGRF1</name>
        <name evidence="6" type="ORF">HK099_007088</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000066">
        <property type="protein sequence ID" value="KAJ3225262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9M4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF362">
        <property type="entry name" value="RAS GUANINE NUCLEOTIDE EXCHANGE FACTOR E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="313"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="679"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="187"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="604"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="609"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="885" mass="99517" checksum="5A3F940B16634DD6" modified="2024-05-29" version="1">MRIKLPIPIKSEKDELKSYSLVSAKEKSPSVEGFSPNLHPNTLSKEMKQMSASEPDVSMEKRELIHLEFEENSMDSVGALGQMKAVKRSSYKVSQIKSLDNFEATHENFISDSQLHSRVGSAVSFSQTNFFKPGAYKTDNSFHERSNSTLSAEEELGSCTFNFTPLLNVVDESPTFNAPTSRALMKSLRSDSCSSTKEIEPTPISKKQSNSSNFSIGSVSSFDESTPRNLFATNKENNKTLNTNKGDVYKQLKFAKKPLGTIYLKDEQFKDMKSRVMNLLFVALDLKEDSSSADISGYRWLSYNNAVCETVNGKKLIKAASLPCLIHILISGISLDHDFLSDFLRTYRYAGESLDVARLLILTYIDAKNAAAVDLDSTFEKKVNESNIQMTLEERCNNIQMKILNILKKWIGEHSCDFERDTVLCALMKTFLNAKVQTDPKKAPFAVRMLEQLQAFNTNTQKIPYFTTKSSSEVSNADYQKPSMELRLSKTEINLDIPLLTSRDSIIELENNKVKSPRRIKISTKPVESSSINLNSYHLDPKPPISENSSVLSDNLFKQTSLLSFSNSENQNFVEDDEATYKESKNISLNMAVLNRNLSETPASDSLFSPVSQSTSYTSSSAPTSPTRSSVGSYIQPQLFPKAERPKTIGGYHGLKFIIMGTAYELQPKLNKISILDFDSEDLAKQITLIEHKLFREIPLHEFYCQSWNDKTYLKSPNLVKLINWFNHMSLGFASEVVRQHDLKKRVGVLKKLIFTAHCCVNWVCCEGSYRTYRSSLSTLKAASGSAPMLPYIGISLSDLTFTEDGNPTFVTEGGENNSLSVINFSKLRMISQILSTISEQLRSPHYQFTCQSNVQDWLLEEMHIMTESELYTQSKLCEPKGVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA95</accession>
    <name>A0AAD5UA95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Long-chain-fatty-acid--CoA ligase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ACSL1</name>
        <name evidence="4" type="ORF">HK099_002920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA95"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="107"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="743" mass="83835" checksum="089DD590E9605A85" modified="2024-05-29" version="1">MLAALIVTFLAIAIVIGIFYLKNVQKFIVSDVPKKSLELQAILSPTKNDGESHILRNSKTPFGKPLVQSIDENSRTVYDMFQAGLKRNPEADYLGKRINDGPFVFESYRTVAKRVINFGSGAKALFNLDTQSKFGIFFKNTPEWAIIDHSCSSYSLVSVPMYETYDEESLKYIVNNSSISVVATAVSGIDKVFAIKSNTEVLKFVVIVDQDEIPEALSQRADELNLKLFTLKQVEKYGEKDILPVVPPKDSDVYTICYTSGTTGAPKGVMQTHRYFAAAVAAILELIPADKIPSSKDRHISYLPLAHVFERSISLMATYFGCKIGYYRGDILKLFDDIEQLKPTIFPSVPRLLSRLYDKIVLSVSNSSFIKKQIFNFAFQQKLKLLRNGIVTKNSVWDKLVFGKIQKKLGGEVRFMITGAAPIAADVMDYLRVLFGCNILEAYGQTEALGFYSSWGDYQWPYGSHVGTPFSSSEAKLIDVPSMNYYSTDKPNPRGEILIRGNVCMKGYFNDSEKTRETLDAEGWVHTGDVGELLPNLTLKIVDRVKNIFKLSQGEYIIPEKIEMKIKSPEILQSFVYGNSLMSHLVAIIIPDSETIFSFAKKHGIECSKLSELCQSEQLKKIILNQINVDGLKNGLHKFEIPKAIYLHSEQFSVENGLLTPTFKLKRKVVQDKFQKELDMLYSDNLKNGKAFMQQNIFNQVLLELIKVHGSLRCKNENCKRMVNEELVGRLWNRDDVASNMKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAR3</accession>
    <name>A0AAD5UAR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase plk4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PLK4</name>
        <name evidence="9" type="ORF">HK099_004520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.30">
        <property type="entry name" value="POLO box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036947">
        <property type="entry name" value="POLO_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="488" mass="54386" checksum="BCD7BD5D4DC78940" modified="2024-05-29" version="1">MGNTTINDFIVNSELGRGAFGIVYSAIRKSDGRKVAIKKIDKEKMRRNNVLNRGPITEKQLRPLLKDLIDGLLYLHSKNIIHRDLKLSNLLLTKNHLKIADFGLAVKLSQQEQKTLCGTPNYISPEIVKRQPYGLASDAWSLGCMIVTLLTGSPPFEDPVKRPKMSWLLQHQFFDTSLLNSELVANGLPRVDSAVGSLARSSQSCHLNKKVVEIKDFKRTANNLTNNENMKFYNNASLKGAHHTTSKVSNESGNVHEYAGCNILENLRNVSILFAPSQINSSIEISTAPLDNEKDGAKFTMNLSEKNADIPSFLIPLFKHSQDCLTQCLEIENIASKDPNTLYPLILKSHNTINQSATMDLGSKPMSVFQRSLSTMATQKGNNPILKETINTCSSRTRVASVLNAPTNSLHQQPVFLNDVGWCIKLSSDEEDLYCMLFLDGVNVTLECKQQTLLYRNSKGDQSIDKSLPSFAKEKLGFFPKFLGLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBH9</accession>
    <name>A0AAD5UBH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="469" mass="54125" checksum="69F2BA40CE4C8B51" modified="2024-05-29" version="1">MNVLLLFTSMAGISLYMPFCWLIGDIFSITGAVLNLSIFTVILQSVLFFLLDGLFLSQHFYYGRKNKRVESAGDIESIIHLHNNDSKSAKSVDSPKKVNENPLETSFHGSYLFYQGPQFHESVYGSFKSLRSNSKVSRNSSLSIRSIETVDITLPSPSMQSVPSMCEHRPSMYGSPLFSPPLSPELHYMSRRLNLSFNSAQNNKLNPKPSFKTTRSLYIIGIMVFFSTSLTNFWHQNLLSESNQSRIFSRGSNLMESSDVNTESGFKDRQLLAEIFGYISMILYSFGGRIPQIYLNFRRKSVNGLNFKMFFFSLIANFLSIMSILFYSVQFYYLFHNLPWILMSSFAIIFDAFIVFQFYLYRNDKKLSKIKVLPYHETTIETEERNINLEIITQNEQYEIVSERTEILSTVKYKEKENNNHTTHSSTGQDEIEKQINENKFQNCIDSYLGRQCSDISEASKETNLEKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRT7</accession>
    <name>A0AAD5XRT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003001</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002031">
        <property type="protein sequence ID" value="KAJ3199817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRT7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3199817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="33427" checksum="787EE738E96B00CD" modified="2024-05-29" version="1" fragment="single">MSHLSKRFIGRIFWRLRGVHPSQIKQDTDDIKNVIAKVIEQKKSRQSAATSLKEKAGGNFKMDVLDRLMEDGYKNTSKESAFTEEELKDEIFAFFLALLQISKNPNNNVIFTSFSGHETTANTMTFVVLELAKHPKILEKVRAEVTEVLKLGNGTLTYENLGHLKYVEAVIKESQRLYPVVPFLSRSSQKDQTLLNYSIPKGSRVMVNIIGLHKNPLYWKNPNEFLPERWIEEGFAPVSGSYIPFGDGPTNCIGQKLAMIEMKTVISMLFYEYEIALVEGQDLEPVSTGTMGLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRV2</accession>
    <name>A0AAD5XRV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002826</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001975">
        <property type="protein sequence ID" value="KAJ3200077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRV2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000033">
        <property type="term" value="F:alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392:SF1">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3200077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="345" mass="40251" checksum="82F79CD3B930B333" modified="2024-05-29" version="1" fragment="single">LDSDPKDFTLLGEHLRMYKKYYNGMKIPHKDPNSFKLISKVYSNLENKLFPWLKSSSYQTVFELENSIKDEQGIVMCVGDKYATMTFATIKIIREVFKSNLPFELFYFGESDLTIENRAKFSAMDGVVVKDLKSYINDDELQLSGIHYTNEGAYFFHDRTWPEITLSRMMVKFLKTVLPENIPKLVSDLHLMQLTTFHEMESGVVLMDKSRHLIGLLAACSLISKKERKPFNYDHYGDKELFWIGLAVVRENFTFSKYESTGVLGVSTYHRGLYTMCNLQILHLDEEDNPLWFNGGLFENKKVEQKFGLNNRLAELTEYLVEPGYWEKEGFCLVKEEEPIKFNDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS58</accession>
    <name>A0AAD5XS58_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BROMI C-terminal Rab TBC-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001649">
        <property type="protein sequence ID" value="KAJ3201931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS58"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055392">
        <property type="entry name" value="BROMI_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23440">
        <property type="entry name" value="BROMI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BROMI C-terminal Rab TBC-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="290" mass="33504" checksum="83AF359D52020333" modified="2024-05-29" version="1" fragment="single">YIIDDNTLLRNLIIISTSSVGGYSEKETENYDFENFVTTLNLKIFDNKQCLSDIKLPDISMEFEADSYTFDKIIDISEDSLTKIEKIKNYFFGKELWQNFESNLTLDFVSFILKYSLDTASKFSTENAKKLGWECIQNRKNKKSNEVKVFTEFEELGLDLAINYASRILKIKELSVIKKKLKEVLNAVNFEKAMDEEFSGFDWFTVIIFIIFNGNTNETIEFLTKFENYLPSLYLWPTCSLNVTKRNSGITLLFSTSIHLVEAIMEEELPLVSSAFILSGCTPSQVKRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSH7</accession>
    <name>A0AAD5XSH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001184">
        <property type="protein sequence ID" value="KAJ3205704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSH7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3205704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="345" mass="38279" checksum="54F9CA1F8AAA986B" modified="2024-05-29" version="1" fragment="single">MNKLPNSSSDPPANQLLPVVLTKPNLNHKPINSLFSKPKKQKNHNAKLLYKHSKSATNSQFSRPAPDTPLLHSLNKSLSSLPTNQTDSVFKPSNLVISLSSNSPTDHATASNNNIPSPHISDEIYYESILDRTLRTNPKVSFECNSTKDTANVSFADSASQTSEDFNRSSFLYRVQPSSDYKPNHQQQLEDEINKIQWSNLSKNPMSTSYNFPLASTPVNIRPSINTDEFFKNYKDSHEDSQVILSTSPLSNFSHELTLEPPNNCIKPSPKKSHSSTFQWNFNAVAGQERFNCGSSDGGGSVTSSASSFSTLPSNLSSPGPERIYYNNFDKSQLPWSSVNLNYRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTQ9</accession>
    <name>A0AAD5XTQ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="6">5.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">INO1</name>
        <name evidence="17" type="ORF">HK099_007425</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10716"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="5.5.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000719">
        <property type="protein sequence ID" value="KAJ3213358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTQ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000069">
        <property type="entry name" value="Inositol-3-phosphate synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000204">
        <property type="entry name" value="Inositol-3-phosphate synthase 1-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000055">
        <property type="entry name" value="Putative myo-inositol-1-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11510">
        <property type="entry name" value="MYO-INOSITOL-1 PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07994">
        <property type="entry name" value="NAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0398">Inositol biosynthesis</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myo-inositol-1-phosphate synthase GAPDH-like" evidence="15">
        <location>
            <begin position="311"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="16">
        <location>
            <begin position="605"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3213358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1095" mass="123395" checksum="4B90AA2DA46797C9" modified="2024-05-29" version="1">MNNNTSSHFKVNSKNVTYTKDHIVSNYWYKNSKVETSGHGEITVTPTEKFFQFRTQLKVPKVGLMMVGWGGNNGSTLTASIIANRQNISWETKEGTQQPNYYGSLTQASTLSIGKDNNQNEVFIPFNKILPMVHPNDLVLGGWDISSLNLADAMKRAKVLDYDLQRQVSKEMEQFSPLPSVYSPDFIAGNQADRADNLIKGTMQEQMEQIRKDIKNFKQLHDLDTVIVLWTANTERYADIIPGVNETMEELLESIKKGHEEVSPSTLFAVASILEGSPFINGSPQNTFVPGCIQLANAKKVYIGGDDFKSGQTKMKSVLVDFLVNAGIKPLSITSYNHLGNNDGKNLNEQKQFRSKEISKSSVVDDMVAANGILYKKDEHPDHIVVIKYCPSVGDSKRALDEYVSEIFMGGRNTISMFNVCEDSLLASPLILDLVILTELMQRIEYRNSSEEEFRPFNSVLSILSYMLKAPLVPEGTPVINALSKQRSALENIFRACIGLDPINDMMLECQDIFDNAKITDIPDKIHYHGPYLKYSGSGSLEKWEGSVLIASQASVPPVLTITQVGNPSFKKLVKGLHLAHHLETLKHIFFWRFDLSLPFGNGHETIQYTYNINGEVEKSFTFHVAGKEDRNWNWSFYSCNGLSQDVTPEEKLKIGGVTPLWKDLMEKHSKKPFHTMIGGGDQVYADPFWFELQSIKDWLALKGKQTKHDHPWSDQFETEVSFFFFNLYTQSWAEQYMKEAFATIPQVNMLDDHDIWDGFGTYPVFLNESNVFQGCKRIAVTMYLLFQHHTTFELACTKDGYFGHQNKSYSCVRQFGPETTIIAIDARNERTLEQIITPESFTILERKLEELTPPSSKHLVVVTGVPVIHPRLEFAEKANTTFGELKTSTNKFANDVKATLPFLGGAIDGLKKSIGKTGLFKNLINQFGLPELADDLQDHWTHEAHAAERLRLVEILQKYSERRRIRVTFIAGDVHLALFGKFYNGSDPESLDHHLMFQVTSSAIGNIPPPGPVVSSVASNGKNIHELNSHTKEAMIKLFDKDVNGKDLDECCIGRRNYATISHEGQNLIFTTLVEPIEKDQPCVPYSLTVPPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUA5</accession>
    <name>A0AAD5XUA5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003438</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002251">
        <property type="protein sequence ID" value="KAJ3198838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUA5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="5">
        <location>
            <begin position="44"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3198838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="21507" checksum="582284EC7F8AC828" modified="2024-05-29" version="1">MSTNQFSYILLPKDVQKDSILYSWANGITLNADGEAEMGKSQMIRPGNCLQLKDIPVGTTIHNIALRDGGPAKLCRSAGTYGQVLFTAPTGHAQVRLSSKEVRLLPVNAIATIGIVGNLDHHNRQLGKAGVARRMGRRPIVRGIAQSPYNHPHGGGRKSKGNKAPRSPWGWKTKGWKTVRRKKWYIVTPKRLARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUC3</accession>
    <name>A0AAD5XUC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apoptotic chromatin condensation inducer in the nucleus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ACIN1</name>
        <name evidence="5" type="ORF">HK099_006429</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000553">
        <property type="protein sequence ID" value="KAJ3215301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUC3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12432">
        <property type="entry name" value="RRM_ACINU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034257">
        <property type="entry name" value="Acinus_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031">
        <property type="entry name" value="SAP DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031:SF3">
        <property type="entry name" value="SAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAP" evidence="4">
        <location>
            <begin position="7"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="304"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="253"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="405"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="585"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="632"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="656" mass="73787" checksum="2E480DECC64B868D" modified="2024-05-29" version="1">MESSNEFSKMNVNELKAELAKHKLPVKGRKSELLTRLTAYTEEKKSLKGDIENANEDTAVSKQPLNVGKPSNNVENSPVRKTKKKSLSPEKDKLSSPAKATDEEPAEKIKIVGDLDILLNKEEKNDIVEKTVLKRDRSNSPSRVEKNTISASENVNFSVEKKLKLDNETKSSTSVMVADTKITSHYEERIINTATKILSPKRDSPNRNSNINKNISKNDAGEESCTLKEEHILHTKKESSLVSSDVTRSTVVPKEKFDDANSTKKTEQINTEKISEGNQEATKTSGVKSPVHVNESSEENHNSEIVYVKNLTRPLREIDFRAFVSEYGEVTSLWMDSLKSMAIITYSNSVQAMQAKNGLHGLTYPDVNKKTLETSFLLPTEVDSIQSQNAKRRSIVQETRQRAIEKQIMGSSANSSVRNKDDGRHRRKEEELLSFKKNREEEEKQKSKVSVQKGKDMEKSDTPDFIIPELPLYNSLNISEKTKFKKTKSLPEIYYLPRIESENLKKKDLNEKIQGEENGSTVNSVKRKAESDEHPDIKEKRSRSRSLNRDKSSKATKQNVSSLTTTETEAVEPIANKSIEKRNKSSSPKHLSKNEGGSASPTKIKKKDLKDHVDTHNDSVNLKSKVSNEISEAEKSNVDVETNKKLSEVSSKSSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVY3</accession>
    <name>A0AAD5XVY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000270">
        <property type="protein sequence ID" value="KAJ3220830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVY3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054498">
        <property type="entry name" value="2H-SAK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052732">
        <property type="entry name" value="Cell-binding_unc_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057023">
        <property type="entry name" value="PTP-SAK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021122">
        <property type="entry name" value="RNA_ligase_dom_REL/Rnl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43883:SF1">
        <property type="entry name" value="GLUCONOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43883">
        <property type="entry name" value="SLR0207 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22547">
        <property type="entry name" value="2H-SAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22784">
        <property type="entry name" value="PTP-SAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09414">
        <property type="entry name" value="RNA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="288"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="3">
        <location>
            <begin position="431"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="965" mass="111177" checksum="2DB2FAA192499416" modified="2024-05-29" version="1">MLKINKGTLAIFLDDFNNLNIPTDLVAEIHQNYQQKRDNSVRHLTVLTPSESTKYNIQEVEKYLQLNAPKFYYLGLGKLKKNATSFIVVGCPQIQLARHQVGLHFKDLHITVGFDFKDTHDENAEKGASSLYDTKIELSFGSPQEILDCLKEHWKLLYFQKENLKKCMLQFSIDLSTFGLNLIEKKPNSEENVAVQVKILNIRSLAFFHARNFEKSMSDAMESNLIAKGNFNESILRLADSSFKLKLYEISAICYWKLFLSYNISSDENSQKLGSHCLKILNKLWSLNKVILETLMFSKENFDFLTASKLFLNEEEHKQYLDYRMDIMSPSEDIEEILDATSDRVMMRNYLKASSYLLPRRFSWIVPLLLAGMSIPRSKEDIVALKEMGVSAVISLTEEKPLDESWFIETDVKLYFWPLTDYFPPSIAHVDKFMEIVLQHFTEKKGSILVHCMGGIGRTGSFLACYLFRFGLKSPPELCDRCKLNPAIFCDDSFCALGYHPVMSATDAISLLRSIRPRSVQTEQQERFIALYSCEIYKRIHLKRRIFNVVVEEMNEKTNGVINFVGEKTANWQLMILCGLPGSGKSYFSKLLAKKKKNCIRISQDEAGNKSICENLVSNYSKTLGKNQLIIDKCNPTPQDRLHWFNLANCSIKDCIVIYFSASPEICLKRCEQRLSHETVKPNSAKNVVESFHKQFVVPDIKKEKFNALYTVSSFADANLLLKEFGVNVDTQENDFVFIKYPRTRHLYDLGSATRDDLVLAETDSEAFLNMANKQFSLTIEEKIDGANLGFRLNEKGEIVCQNRSHYVNTASHYQFQNLNSWIFQNKEALLKILSQKIILFGEWMFAKHSIFYDNLPDVFIAFDAYSIIDKKFFSRRRFLKLLEGSGINSVPIVDHPQILDKDNILKLIYLPSNFSQSAQREGLVLRRDDKDWLHDKAKIVRPGFISGSEHWTKGIIQKNIFNYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVZ1</accession>
    <name>A0AAD5XVZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cleavage and polyadenylation specificity factor subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cleavage and polyadenylation specificity factor 100 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CPSF2</name>
        <name evidence="9" type="ORF">HK099_003936</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000267">
        <property type="protein sequence ID" value="KAJ3220872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16293">
        <property type="entry name" value="CPSF2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000008">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027075">
        <property type="entry name" value="CPSF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025069">
        <property type="entry name" value="Cpsf2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035639">
        <property type="entry name" value="CPSF2_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922:SF1">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13299">
        <property type="entry name" value="CPSF100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="17"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="8">
        <location>
            <begin position="248"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3220872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="827" mass="94653" checksum="B41455284FEEB50A" modified="2024-05-29" version="1">MSYIKFTSYSGAVGDEGPLCYLLEIDEAKILLDCGSSESFKNDEIFDNLKKIVPKIDAVLLSHPDLKHLGAFPLLHKFGLKCPCYATIPVHNQGSMALVEAYQSLINYEEFELFNLSDIDNSFDKIIQLRYSQPVILQGRNVKGITVTAHPAGHTIGGTVWKIVKDTDQIVYAVDYNHKKEQHLNGTILHLDNGILSRPSILITDSYNNLVQQPGRKERDKLLLDSILNNLTTTTSTILLPIETTTRILEVAYLLEQHWATHQLSHPIIWLAYTSDKSLNYAKSTLEWMSERINTQFSEKRDNPFELRNVKCVQNIKELSKFSQMGRIVLTSMASPVKSMDHGFSHILLQQLGTDPDTLVILTDRGSPDSLCRSLYKKWESELENNEVKGEIKLNMEVDFVQKEKIPLQGAELENYKRAEIEKNIIEDLMKKKEEVDELDSDSDLEEEILKENLKFLNNNQNNPEFSNFGDFQQNQYDIHLKDNKKKNQFGSVNASNVIGTSFFKHSNRIFKMFPVVEKRLKYDDYGEIFDPTIYMTGEFQSVIAQKLIDEEELQDEENFKKKEVFVPSKYTKLDISIKLVCKLIYIDFEGLTDGVSIRNILPQVNPRKLILIHGNAQSTTSLKEHLVNLNNFTKEIFCPAKYECINVSSARNIYQVKLTDSLFSSLRMSKVDDYDLSYIQGIIKFPEIEKNVKIEGETIKTETESQNDEIKNLVKQETKEDEIFSIIPHLDIIPFRKRPFRKPVLVGEIKLSSFNKILQQNGFQTKFKNGILTVNNKLTLRKKDESVSRNDGTSASAGTGGLILEGACDKNFYLVRKLLYNQMAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWA9</accession>
    <name>A0AAD5XWA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000750">
        <property type="protein sequence ID" value="KAJ3213063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="200" mass="23157" checksum="576FED54AC3B763E" modified="2024-05-29" version="1" fragment="single">IKIDIKTKYYRKMNKVNTNRFSASFRIKKERLSVLTQAELEQEQLKTIHFDAVIKNGETTRISLHNDEKNDLLQNNNIITSPIFEIPFSTAQDSKKNRSSLMKRNNKKSKIQSISVVLTDTWKQVVKSLKQGEKTTIKPEEKERDTLVDLNTIDKVVENSFTDSLCEITVRSREDYLSRQDSISDTSTLTIVQEEGHYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWN1</accession>
    <name>A0AAD5XWN1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001722">
        <property type="protein sequence ID" value="KAJ3201468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWN1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2730">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="60" mass="6506" checksum="10EEAB54D5C31589" modified="2024-05-29" version="1" fragment="single">APSEVDVEALRHENEQLKKKVDELQSQLDELNSSKKDGVVDPSVAADTLVATSTNEEVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWR8</accession>
    <name>A0AAD5XWR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_006855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000619">
        <property type="protein sequence ID" value="KAJ3214453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWR8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042220667" evidence="9">
        <location>
            <begin position="18"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="301"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3214453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="474" mass="52719" checksum="00FDB8953D06AABD" modified="2024-05-29" version="1">MVQKLLFASFICTPVLSWGLEGHFSVAGVAEKYLNEKTKSFVKYFTENDAPFINGSIWADSVKYNDKVPGIPFYPWSKNLHFADTFDDPTTGNCTYDDHAVHEEFKEEYIIPLHVCGDQIGGNGRKVFLYNGKSNSTFTNDAGKTFNSFLNLHHIWDVEIVVQRMQEVIKSEYEPLNRNYVASMEPINEFVDYLYNKLEEGKGDFANKENWVKTLDSDWDKVNEVGHWVTPIEWAVDSNGFNCKYVYPDYLKDIKADLATNGYYETVKTAIDIQIAKGGFRLANVLNRAFASCELPLTTATPQASTVSTATPHASTASTATPQASTASTAAPYTSTVVGSTTVGVTYQTASLVKNNGGNPSATPYNPYGSIKYHSEKPYVAPSPTKAEPVYPSYPAAKVVDEKAYKGYPAAKVDEGKEEKAYKGYPAAKVVEEKQEKGYKGYLENKALPTKKVSKEEYPSTSNVAKVHKQKCHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWY9</accession>
    <name>A0AAD5XWY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Cytochrome c oxidase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">COX3</name>
        <name evidence="11" type="ORF">HK099_002071</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000166">
        <property type="protein sequence ID" value="KAJ3222632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWY9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="entry name" value="Cytochrome c oxidase, subunit III, four-helix bundle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403:SF7">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="Cytochrome c oxidase subunit III-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Heme-copper oxidase subunit III family profile" evidence="10">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3222632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="107" mass="11929" checksum="8C8FFFB7B99A9BB2" modified="2024-05-29" version="1">MSRQVHPYHLVDGSPWPILMAFALLGFAVSIIGILIISIQWWRDVIREAKGGYHTITITEIMLFGSFFWSFFHASLSPAIDLGSTWPPMGINAVNTWAIPLLGTCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX94</accession>
    <name>A0AAD5XX94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cullin-4A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CUL4A</name>
        <name evidence="1" type="ORF">HK099_005939</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000488">
        <property type="protein sequence ID" value="KAJ3216257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX94"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00719">
        <property type="entry name" value="GIY-YIG_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="274" mass="31420" checksum="98A11759BB8D5059" modified="2024-05-29" version="1">MIYVLLLEQGKFYVGYTARPTGERFLEHFNSHGSKWTTKYRPLQVLEFREGGQHDENFVTLQIMEKYGWWNVRGGNWCNVEMTNCPPALLKHQKLVLPDELKRANINSSRGGNSVKSANMITNCNFCIRCGRRSHSINSCYASTDIDGFSLNESSSNDSSMEESSASEAEEEFGDNSCYRCGRLGHFSVEDLALSFEKSLKENGIIAVHSKTTMGDPSLRFIYEHDTLTAQQLNFLTDLLKNFRNVDGFYVDVSYSSNEKWQNERMKFGWKKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXA2</accession>
    <name>A0AAD5XXA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000123">
        <property type="protein sequence ID" value="KAJ3223614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXA2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="224" mass="25397" checksum="AE16B39CB4215584" modified="2024-05-29" version="1">MGGVHMDSVTFDEEFLQTIKMSLSSLKCLLKRSFVSLNESFSKSLFHKSLDVFFGDPLSKTGPALIAILCDHCYDLIKLLEYINTVLTTRHEFGNAKIRLSRSEVTNEDLMSIYLYSLTINKKAVDESSSEDCSSSSDTTNAEVEGLISSLNIYDPIADELRKYQQTAKQSHHWVEEARIRLSVFSKHGITQFLAGSRYDIDILSDAWSKLLYMRISLKMVLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXM8</accession>
    <name>A0AAD5XXM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phenylalanine 4-monooxygenase</fullName>
            <ecNumber evidence="4">1.14.16.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phe-4-monooxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_007271</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.16.1" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000693">
        <property type="protein sequence ID" value="KAJ3213622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004505">
        <property type="term" value="F:phenylalanine 4-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04880">
        <property type="entry name" value="ACT_AAAH-PDT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03347">
        <property type="entry name" value="eu_PheOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.800.10:FF:000004">
        <property type="entry name" value="Tyrosine 3-monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.800.10">
        <property type="entry name" value="Aromatic amino acid hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001273">
        <property type="entry name" value="ArAA_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018301">
        <property type="entry name" value="ArAA_hydroxylase_Fe/CU_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036951">
        <property type="entry name" value="ArAA_hydroxylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036329">
        <property type="entry name" value="Aro-AA_hydroxylase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019774">
        <property type="entry name" value="Aromatic-AA_hydroxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041912">
        <property type="entry name" value="Euk_PheOH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019773">
        <property type="entry name" value="Tyrosine_3-monooxygenase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11473">
        <property type="entry name" value="AROMATIC AMINO ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11473:SF24">
        <property type="entry name" value="PHENYLALANINE-4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00351">
        <property type="entry name" value="Biopterin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000336">
        <property type="entry name" value="TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00372">
        <property type="entry name" value="FYWHYDRXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56534">
        <property type="entry name" value="Aromatic aminoacid monoxygenases, catalytic and oligomerization domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00367">
        <property type="entry name" value="BH4_AAA_HYDROXYL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51410">
        <property type="entry name" value="BH4_AAA_HYDROXYL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0408">Iron</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="79"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Biopterin-dependent aromatic amino acid hydroxylase family profile" evidence="13">
        <location>
            <begin position="152"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000336-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601273-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3213622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="482" mass="55029" checksum="703A878199DB7831" modified="2024-05-29" version="1">MNFKTLLKSNYKSTAYFCNLKTNRRLLHSFQISRNVPTLFSKNSSVRLHSNKSTNNPYTFSYVSKENESALVNSVIKTTIHFSITDKVGALDEVLSAIKALHVSLCRIESRPSRTKGSYDFFIDFETTEHSKVVDTLSVMSKLVKDIKIVSSGEKDTDDDLHSVPWFPRKIQDLDSFAEKVLSYGADLDADHPGFTDAVYRKRRADITEKAKVYKHGNPLPHVEYTPAEIKTWGIVFNELVELFKTHACREHQYVFPLLVQNCGYREDNIPQLEDVSRFLKDCTGWTIRPVMGLLSSRDFLNGLAFRVFHSTQYIRHHSRPLYTPEPDVCHELLGHVPLYADPDFADFSHEIGIASLGATDEDIEKLATIYWFTVEFGLCKEGNNIKAFGAGLLSSFGELEYALSDKPIKKPFDPAVTALQKFPITEYQPIYFVAQSFKEMKEQVIDYASELKRPFTVRYNGLTQSIEVLDTKEKLMRYANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXP8</accession>
    <name>A0AAD5XXP8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_008208</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXP8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000014">
        <property type="entry name" value="Protein hob3, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BAR" evidence="12">
        <location>
            <begin position="17"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="266"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3224599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1098" mass="124930" checksum="EDDAF8250AA69412" modified="2024-05-29" version="1">MSWKGFKKVVDRATTSVMMQTGYIDKTTDKQFDDQEKRFKSYEAKVEKLHTEAKGYLDAVRAMTLSQTRIAETVDGFYEDGTQLGDAAIKYKDIVKSLDEKDRDELDKTFRETVLDPIGKLAATFPEFNETIKKRQKKLLDYDKTRSAVKRLVDKPSDDKSRLPQAEEENQQAKELYDRLNNTLLEEIPKVIDLRVLYLNPCFESLVLSQLEFNKQAFLKFDGLKRHFQTDDSNIGLIEDQIENVLGQMRELTFGRSNGQQMFGPYYLFNTIGEGEFGKVKLAKHKDFMQRDVCVKLIKKENVNNASKRTKLTREISILQSLDHPFIVKLLEVIETQQYIGMVMEIASGGELFEHILARKYLKEKEACRYFVQLISGLQYLHAHKYVHRDLKLENLLLDGNRNIIITDFGFANKSDGKDSLFNTSCGSPCYAAPELVISDGYVGEAADIWSCGVILFAMLCGYLPYDDDPANPDGDNINLLYKYILETELVMPDYLSEDAKHLLKRMLVPDPKYRAKMDEIVKHSWLKPYREILEESMNYMEITMSEQLQVVPDRKSTISMKNETEELTVSVMDITDISGEGEEPSVDVQFTSTTTISKTEVNSRESIEILNLQPIETVKVVDNTFELNKLNGNGEDYVANTTDEETDSEAEQIPAEVATIKIVPFPHPVENAVSTNLLADPQQVLKKASDSSHMSIDMEIPSGEGLMLEIMSQVNYTRQVDADELSSATVKKIILHKTSKSTIKRVPSVALPNNISRNELLQAVSRNSIKDSSHNFKEKIVTEKRKSVLGKSSNVILPESSCFQGNNAKVYFPTLSSEPVIVEPTRYTKSMDVWRIDRYNLNGEKSKFSSNRDEFSQMMQFPTASEKKSTSARTVVKSKKNKYYHTKLNTPVLNEEHGESLSTFATSTLKYSKLRYHSGPIDQRALTNRTPIHLLDDIFNLLLKLGMLVSYSKSDGSSFKLKVLRPQHLSHIEKNDNSDNGDKLNREVNLKDGNIENSDSGSANCIEHPPQLNEPNHGRSNISKLFISSFPLSLMKRIKYMATHGQNWNKGFDGREEYSCKKENMFSSTSDSTLSEFGEVKFHIEIQKIKNLKGITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXQ1</accession>
    <name>A0AAD5XXQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000676">
        <property type="protein sequence ID" value="KAJ3213794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXQ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="333" mass="38207" checksum="699562B8ABD70568" modified="2024-05-29" version="1">MVITNKPNNQISLLPHDNEETMSTSFHVTFLNNSNKTNPHLSLNSLQLVGSSASTILDNVSEFENFSLSENGFSDKIDSEDGLSFGSTVDDIMDEKRFSDLSASERVLSLEKQNEEIGNRLKMRDSYLQETILDTSKTLNSLKEQLAKAEDRNMELERELEILTIEREQFEENIKILHKKLDEFSLPNTNYEFGDATTPYSFSNKNTLNNITPTFFRQQNSTLKSSLLEFISPVQSVVEKKEIGLNTDIKRQKDFKEIGLNTDIKKPTDYKEIGLNTNISWESELLKLKEEKDEVWNFFLFTKAKQKNQETQTASTSFNSILFESDEISKETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXU2</accession>
    <name>A0AAD5XXU2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_008196</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXU2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23649">
        <property type="entry name" value="Khc_CBD_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01369">
        <property type="entry name" value="KISc_KHC_KIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000031">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059182">
        <property type="entry name" value="Khc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 9 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="13">
        <location>
            <begin position="4"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="523"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="909"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="420"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="605"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="807"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="538"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="86"/>
            <end position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3224587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="960" mass="108019" checksum="D7E4279C4FBA906B" modified="2024-05-29" version="1">MSNNIKVVCRFRPQNKREIAEGGVPITLFNDDMDTVKLDSKEFPGSYTFDKVFDWKTSQSQLFDYTSAATIADVMKGYNGTIFAYGQTGSGKTHTMMGDMENPEMQGLTPRLVQTIFDTILKAPDTLEFTVKVSFMEIYMEKVKDLLNPVNDNLPIHEEKSKGVYVKGLLEVFVGSVEEVYDAMKRGQENRVVAFTKMNAESSRSHSIFVLHVSQKNLTDGSTRVGKLSLVDLAGSEKIGKTGATGQTLEEAKKINKSLSALGMVINALTDGKSAHIPYRDSKLTRILQESLGGNSKTTLIINCSPSSFNEAETVGTLRFGMRAKTIANKAKVNAELSAGELKVMLKKAKIEISSLRDYAGSLEGELASWRTGASVSQSDWVPLQDHKKIASSKSTEIVESVEVAAKATVAATSLTNDEREEFLKRENELSDLLAEKEAELKKKSSDYLNLKEELTELKEKDGETSTENKALSTEVNDAKLQLEKALFDFKESSITIDSLKESNNELYKEIENLKKYISELESRPEYPTPSASPQPQQDKEQKKQERMAQMMAEFDPSNIILDKEQQMRETLSKLASMDDNTQPPTEAADIEQQHRDLHLIRIQLAQSQQHIQELTLKVKEHEEKSHHLAESKLELEEKLIGLESEYEQLLDRTIIEDEQHASVEMSTAIQDIKSKLEAQFNNKREVQEKEIEELHIALDKKEEENALEALNNANGTSVDGFKKDEEIDKLRKTMAQQLSEFDVMKKKLMRDLQDRCEKIVELELSLDETREQYTSLSSDPERFSKLESSLEETRKKYNTILSNSNSKAQQQKLAFMERNLEQLTNIQKQFVEQNSSLKKELSVSERKLAARNERIQNLETLLHEAQKKIEVQSAKFESQVSQLKSKLDVARSQTPSTSSWLYSSSKIAKPLRGGGATPLSGEDDVNSGSSEVEPLSAIKKNLSASTGKRSSWYVNLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY86</accession>
    <name>A0AAD5XY86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EXOSC7</name>
        <name evidence="9" type="ORF">HK099_007813</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000799">
        <property type="protein sequence ID" value="KAJ3212028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY86"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11367">
        <property type="entry name" value="RNase_PH_RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="191"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3212028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="285" mass="31922" checksum="418AF00C4253448F" modified="2024-05-29" version="1" fragment="single">ETNLINQASGSCRVLLDQTDILVGIKVEIGQIEPDNVNDEEDETNLEEDDLSRHNNIVSTEDEDVFGERNKGRIVCNIDCSPSVAKFFEFKKIEEICIEYSQYMNRLLNGKQGGIDLQSLCILKNSTCWIIYIDALVLNYGGNLLDAIFVATRGALQNTRIPKCRVEESQGIFDFEIGDEETEIIEGWREMPVCVTVNKIGNSFILDSTPLEDNCSEARLMVSINRKGQICSVQKDGTGAIEPTLLTEMIRSAQTKGKLILNNLDLVLSNEEKRIENLIECVGFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYP0</accession>
    <name>A0AAD5XYP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005407</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the E(R) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYP0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046452">
        <property type="term" value="P:dihydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2260.10">
        <property type="entry name" value="Enhancer of rudimentary"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035912">
        <property type="entry name" value="EHR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000781">
        <property type="entry name" value="ERH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069:SF3">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01133">
        <property type="entry name" value="ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00070">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143875">
        <property type="entry name" value="ERH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="9">
        <location>
            <begin position="102"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3226181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="304" mass="35529" checksum="AB3E6E3E19EF2DF2" modified="2024-05-29" version="1">MSQHTILLLQKTKDKKSRTYMDCNNVSLMIDQVINLYEVKLKESNINRREINYTASDLLNYIDNVGDLACMVLDVNSGTYIPHDREWIKQMNHTGDLMEGISLNIIVAKTAKNGIGLNNILPWKIKRDMKLFKSLTTSNNKHQGDSDFQNIVIMGRNTWDSIPNKFKPLKDRLNIVLSRNTAFQQLVPPKVQVFQSLEASLNFIKKKSFQNKNIWIIGGSQIYKEVLELNITKKIFLTHIYNEVECNTYIDLKLDKFRLIKDAEEIGIVLKNYFLDGEEQDEFKFNHVFEEDGYKFEFLLFNRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ53</accession>
    <name>A0AAD5XZ53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coatomer subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Beta-coat protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">SEC26</name>
        <name evidence="19" type="ORF">HK099_005116</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000388">
        <property type="protein sequence ID" value="KAJ3218287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ53"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000444">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011710">
        <property type="entry name" value="Coatomer_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016460">
        <property type="entry name" value="COPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029446">
        <property type="entry name" value="COPB1_appendage_platform_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635:SF0">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07718">
        <property type="entry name" value="Coatamer_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14806">
        <property type="entry name" value="Coatomer_b_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="16">
        <location>
            <begin position="212"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit C-terminal" evidence="17">
        <location>
            <begin position="870"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit appendage platform" evidence="18">
        <location>
            <begin position="1011"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="688"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="696"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF07718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF14806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3218287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1146" mass="129531" checksum="71609ECE18FB084C" modified="2024-05-29" version="1" fragment="single">MFSGNNILLDQQQSLAGFQTANQVNILSPNQPSEENPIKFETLKDMKFPYPLESKSNFLTVLNQLIKINDGKNFNLLNNFYLMLSLNHATELLLSFFDQPFIVFDYVVKTLKDKNTYDNVTFFKLKSRMVENNAANVNSRIESMGESCSPNNDINVKQCSNCFQYSNFKLDFLKEFFEVENLKGGPEGSNKILLGIGYYNEIAESYNKDQPTVQDIKSQLESPRDEVKIATMKKLLLLMLNGDPLPQVLMHVIRFIMPSKNKQLKKLLLIYWEICPKLNSDGKLKQEMILMCNALRNDLQHPNEFIRGMTLRFVCKLKEAELLEPTIPTVKACLEHRHPFVRKNAILAISTIYKNFEFLIPDAPELIKKFLHTETDPNAKRNAFLMLMNTNQQSTVEYLDSVWSLITTSFDENLQLAAIELIRKDCKSPGADKAKYIQCIFSLLNSTSHSVKYEAANTLVALSPHSTAVKAAASCYIELVLKESDNNVKLIVLKRLNELREKHDRILDDLIMDILRVLTSPDIEVRRMCLSIAMDMVSNRNVDECVSFLKKELVKTHDQSEYEKNSEYKQLLIHSIHQCAIKFSEVAANVVHVLMEFVGDSGSSSAVDVISFVREVMEKFPHLRSGIIDRLCENFNEMKTSRVFRGALWIIGEYAVEGNSIVESMKQIRNALGEIPILASEQRALEAHDAPEVSAESPSAKTSTTPKRVLADGTYATETSFSANRRGSTKAVSVKPPLRALLLNGDFFLGSVLSTALTKLVSRFEKLSQASSPELKAKANELKAEAMLIMTSIIRIGKSDFPISKIDEDSHERILTCLRVLSIKKSENSNFMNEIFLEDCRNAYKNLVLTDQLKKDEKLKKDKKIIKVHADDLIGFRHLKSKRVLGGTDEYDLDLNMATGNTEKGDKMKNKLSRVIQLTGYSDPVYAEAYVNVHQYDILLDVLIVNQTNETMQNLTLEFSTLGDLKLVERPTPYTLAPHGFHSIKANIKVSSTETGVIFGNIVYDGSSALDMNCVILNDIHIDIMDYINPAYCTESQFRNMWMEFEWENKVNVNTNLTNLREYLDHILKCTNMACLTPENSLQGDCGILAGNLYAKSIFGEDALANICLEWNEGGNISGHIRIRSKTQGIALSLGDKITVSQKGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ85</accession>
    <name>A0AAD5XZ85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002169</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000017">
        <property type="protein sequence ID" value="KAJ3227418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ85"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="2"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Septin-type G" evidence="6">
        <location>
            <begin position="176"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="49288" checksum="E23799392B42A145" modified="2024-05-29" version="1">MSTEIKYEAVCEYTPTHADEIELNVGDIIQILHNYDDGWCLSKNEVTKAVGLLPRNFLVQVGLKANNLTTSNVQSEDEKKKQRASQRQSSLHLNESQLKNLSSLDRKNFIKSPAANSDRISWGLLEDLNSIEMLTGKLDAINVEKKEKIKPKVDPREKIESINEWKKNRVRKIPANIGTLKIMVVGDTGIGKTTLINALLDSKEIVEMNPETLSIKGLMHYECSTIPADQIYMGEEKYNITLVDSLGYSNSTDSASQIRPSVEYLVGQFQQTDKVFSKSIPTNNLIKFLNGGTGGHGFVDVCIYTILHRLKPIDVEYMRVLSPFTNVIPVLIKSDSLQKEEIFELKNSILQQLHNKNDINLFKFGLSSEELIEVSNDVGSIPFAVSLTQENSKNVINELETLKEYLFYYYIDDIRQKTAEKFAAWRSAQSQKLTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZA9</accession>
    <name>A0AAD5XZA9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">4-hydroxyphenylpyruvate dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_004910</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="10">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the 4HPPD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000362">
        <property type="protein sequence ID" value="KAJ3218834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000001">
        <property type="entry name" value="4-hydroxyphenylpyruvate dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959:SF1">
        <property type="entry name" value="4-HYDROXYPHENYLPYRUVATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="VOC" evidence="11">
        <location>
            <begin position="23"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="11">
        <location>
            <begin position="185"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3218834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="386" mass="43511" checksum="9192F28F49E6422B" modified="2024-05-29" version="1">MAESNRALNFPKGPAPTAGRYHGFDHLTFWVGNAKQAATYYITRFGFSPCGYKGLETGSRDVVSHCVSQNGIKFVFQSPLNPGNKYFGDHLVTHGDAVKDVAFTVDNCVAIYEKAVARGAKSIREPWVEEDKHGKVIMATVATYGDVEHTFVERKNYTGNFLPSYTSTLVADPLEAFLPQTNLLYVDHIVGNQPDLEMVKACEFYEKCLDFHRFWSVDDKQIHTEFSALRSIVMADYDEVVKMPINEPAAGKKKSQIQEYVDYHGGAGVQHIALRSENIIDSVSSLRKRGVQFLSVPPSYYENLKLRLDSSNIKVAEDLKKLEELHILVDYDESGYLLQIFTKPLEDRPTLFIEIIQRRGNSGFGAGNFKALFESIEQEQEKRGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZM0</accession>
    <name>A0AAD5XZM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000417">
        <property type="protein sequence ID" value="KAJ3217636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZM0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF13">
        <property type="entry name" value="NADH DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="32"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3217636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="349" mass="38864" checksum="E8F73B2743E8674C" modified="2024-05-29" version="1">MITLKQDLMFKKNLKLSRIFRSITSLGKPKGRIVILGSGWGGYKVLSGLDTKYHEVIVVSPRNHFVFTPLLASTAVGTLEFRAITEPVRRFRDKGITYYSSWCDKIDLNKKEVTCTTALVSKNETFKISFDKLIIAVGAYANTFNIPGVAENSYFLKEISEPNTSEQETINALNFAVVGGGPTGIEFSSELYDFVKEDLSRLYPNLMSKVQITVYDVADTILGGFQKELQEYTSKKFFREGIKIKTKTVIAKVEKNHLILKDGLCVPYGLLVWATGITATPLVRTLDLMEDKASRIITNNMLQVLDQNGKVLDNVFALGDCAAIKDNPLPATAQVGIKSSRRKIDNNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y067</accession>
    <name>A0AAD5Y067_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron hydrogenase large subunit C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008708</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000099">
        <property type="protein sequence ID" value="KAJ3224252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y067"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron hydrogenase large subunit C-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="270" mass="31174" checksum="21FEC6E83F781346" modified="2024-05-29" version="1">MPCYDKKLEASRDDFFNDVLKTRDVDCVLTTNEVQQLFEEYKVDFKICEMEEISSMFTKAGLNSSLNTILYNSKGSTSGGYLLFVMRYAAKVIFNIELTEEEIEFGSEKISIEPGRNNDQKSVSLLGKNGEVLLKFGYAYGFRNIQNLVRKIGEKKRSFRRKTEVNDFNFVEIMACPSGCINGGGQLKPFFITGGVENSSSTPASKEWICLTEKYYFNKNIYFQSPETNSSIHELYKHWLHDDKNRIKEKLHTSYHVIEKLEENGLTVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0S5</accession>
    <name>A0AAD5Y0S5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RFX-type winged-helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000243">
        <property type="protein sequence ID" value="KAJ3221227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0S5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003150">
        <property type="entry name" value="DNA-bd_RFX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039779">
        <property type="entry name" value="RFX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057321">
        <property type="entry name" value="RFX1-4/6/8-like_BCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619">
        <property type="entry name" value="RFX TRANSCRIPTION FACTOR FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR RFX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25340">
        <property type="entry name" value="BCD_RFX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02257">
        <property type="entry name" value="RFX_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51526">
        <property type="entry name" value="RFX_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RFX-type winged-helix" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="316" mass="36797" checksum="581E4501D9ACBE88" modified="2024-05-29" version="1">MEELFFSLYYTKSSDHSESVIRTELYQHYTDYCSENNFKPINVFAFGKKVTEIFPEIKVRRLGKRGDQKYHYAGLAKKTKLNNQSESSKQPKKLRTTEVNPVINAIDFSDVNVSGNQNSSVCNNSITQTKEHQILLDKYNIYCNKMVALVKALQFDEAINLIEEFYSGLKEVEQQLLKLPVINGALKKYDIQLVDILLNLLLPDLFLEYPIEFLSLIRNFTKNFMLALMNFLSDTHRLKENNQILVSTFEQIQYTTHSSSTLDFLDDSGWILNCSKAYFKEIFEKIMLLLKNDSEVEDWLCFVEEKLLENILPNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0W5</accession>
    <name>A0AAD5Y0W5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 12-like conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002228</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000172">
        <property type="protein sequence ID" value="KAJ3222520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012978">
        <property type="entry name" value="HEAT_RRP12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057860">
        <property type="entry name" value="HEAT_RRP12_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052087">
        <property type="entry name" value="RRP12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48287">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48287:SF1">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25772">
        <property type="entry name" value="HEAT_RRP12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08161">
        <property type="entry name" value="RRP12_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRP12 N-terminal HEAT" evidence="6">
        <location>
            <begin position="18"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="RRP12 HEAT" evidence="5">
        <location>
            <begin position="387"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1189"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1324"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1409"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1331"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1375"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1409"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1444"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1470"/>
            <end position="1482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1482" mass="165870" checksum="FD53A0FA5513BB5A" modified="2024-05-29" version="1">MDIFKSTRALATSKLSNQKDAYDTLKAVEEVIIENNEEKCPLAYFSILITMIEQQKEISLNDAKRESLLIASLYLLATVFPHVPSQILKIKFSTIAETLLSTMQLHHKQAPLVRSILNCLEVLLFSQDSKTWNNNLLCNKIFQVVLSHSTDPRPKVRKRAHEAIKRILSNPPPPSIHHPASSCVIDFAVSFIHNSLSMSNPNKEVKAEKESQSMHLLAFLRLTLPIIIRQSANNAKILEKLRSLSVELLKLPIKTSSTGNVMLTQSAFSVLTCFFGRPMELTSSQDDENFPDDFNEIDLNLMLTIINTLLELRPNQNDAVLTPSWVKLIGLGIFKYSDTIKIATANLKDNEVLDETLQDLYKHENENLPELLSLFFSRNFETLLSTSTKEVVIMTASKSFSQLCRNCLTETMIQKANQGSVVEESRSILLDIINLVDHSLEDIRFKDAWGGILLISAALFQRLGRHSPSLVKKILLKAVAFRDDEAYHAVFPYKVELESAIVSASEAMGYEQFLEYIPLNVESGDPKRPYLLSMFVNSKINSNVHTVSNFGSHSLMFFAKVLAPLSSRLFGRSATLTKSQRDREAKLFETLGSQIWDILPKICASTPTDVGSTGFNAISSVLGNILQASDGKCPLPADLVNKKFEIPSTSPDLRPIIYSSLHILLENYIALSKKDLKDDEKNMVESGITVLKQFSTRFLATLCNNFTAPSYDLIENLINQNLISHQNKSQQKTISQSGLISSSKNLVLQALHEKENQKCELAIKSFLKIADQQAMDSYFMNLVKSLLTAQTDARRKKEKSDAMEEEKSPAAILQVQVRTYTMIDLLLLLLPHLSSSKSLSEDGQDLLLGNSPIFLFYKVLVGQLRDEDVTLQKRTYKALNDVVDILMPLSETSSVNRIIRVLPLIDDLATKLIDPEVLVAAGSGSKKARIDLIGKVVKSVPLGVLPAEHNSASVGDALLLNFVPVALSEVMLSTKEASEKARTASFETLAIMANKMLQAGKLYSAVEKVEFREISEEMDIVDNEDSKNAEDTVANDTPEVVRSKLNFGEFLMMIIAGLGGSTSNMQSAAISCVARMLFEFRDEMSDKLIDDLINIVMSMLQSPNREVIKAGLGFVKVVVLTVEQELLTDQLENIITSILNHSRSHTSHFKAKVRHLFERLIRKFSYEAVEGFVPENDKKLVQNIKKRRERLKRKKDDESTGVKTNNAELGSISKQKAFEDVLASDESDLNSDDENISDDDIEDYLPEELKTGVKKGSKARTRIKEDQLESEDVLDFLNSNIISKVTTNSTLKRKKEPLSKESGEFEFSSHGKLMIYDSDEEEKRLKKAGKKNSTIPGEQSNGGNHYIDSLKSESALKRMPNGKVKLANKRKRNDDEMELDEEEENLPKNHGNMNEDKAVDKMLGREFRSKNARGDVKKGAVDPYAYIPLNAKIGSSNGRKRSKTQGSFKSIIKASQSGNDISKPKERRNQKGFKKGNKKHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1L2</accession>
    <name>A0AAD5Y1L2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_002421</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAPRE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1L2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035372">
        <property type="term" value="P:protein localization to microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000028">
        <property type="entry name" value="RP/EB family microtubule-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027328">
        <property type="entry name" value="MAPRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10623">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="11">
        <location>
            <begin position="2"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="109"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="259"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="147"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3227355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="448" mass="51026" checksum="A3DB419067071366" modified="2024-05-29" version="1">MNESKAELISWVNTLLKLDYKKIEELGTGAAYCQIIDSIYGNVAMNKVKFKCYMEHDFLFNYKILQSSFNANNIEKEIFIEQLAKCRQNENYQLLSWLKKYWDTHYGGTQYDPEGRRREKPKSASLIKGKRIEKSNQNLEPVDPENKQVNLKSSLSSTPTGKQKSVKICDAPNLKLPKLPTIKAILNPYIPIPASISKSCPIHSRSSMNAVVSQVPPNSADGKSLNSRPSTGTSEVVSAYSSRSRTGIKDGNYNLKKGLEKYKIRVNDMQRKIDELNLNKSKNESELNNYRLQIEEMKQIMEWKNRDNINEVFEQLNSDHCSYIHQCKDTVLRSSDLKYKIACYNTEKQICGPKPFTKIDGKNLYVKCVSGFKVVDCLKSDYKAWVEKKLKSVVTGEKSVIPAESSSCDLDRCSSSQNNECLVLHQWLPDYFSKVDECCSAGRYEPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y217</accession>
    <name>A0AAD5Y217_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kinetochore-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KNTC1_1</name>
        <name evidence="3" type="ORF">HK099_007986</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000083">
        <property type="protein sequence ID" value="KAJ3224737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y217"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005828">
        <property type="term" value="C:kinetochore microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903394">
        <property type="term" value="P:protein localization to kinetochore involved in kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052802">
        <property type="entry name" value="KNTC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019527">
        <property type="entry name" value="RZZ-complex_KNTC1/ROD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15688">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15688:SF1">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10493">
        <property type="entry name" value="Rod_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RZZ complex subunit KNTC1/ROD C-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="652" mass="75864" checksum="B853FAC2E00E184B" modified="2024-05-29" version="1">MSTFRFPFHALSAEDQSALLVELNESSLPQLYALYRPLNLAQDWFYIKVVEKMILQLKIEIDNSETIPITSHSNLTCNNLKFSDFKPLLIKIKDSNQALQLSVKLAEQFSNAVESINTYKLALNLAERALAKTNEQEEKLINQLENAIDIVQGLLWKKETEYQLLSNNCGDLMEFLTEPTNLITQFYLQKSELGLEEKEDFDLHGIVDEIAARYNLDVQHIRESLIKSWLMQNIEINENEKKKFLPSMQLQSQRSFIFESEKHIENRIIYLLKSQSTQKSTQLLMQVALSENSKVSKLARVRSLNILLRVSSFQEIAAVNKKFPGSTGVRNYLQQLLYLADFEELRIIQDRKDFVDCDKGALVRSLWINHGDEDQRVTHLICNICMDYEIYDQPLWEKCLLQLQNWESYEYLLCLLEHISSKSELSQLSCLPSIWNEVLLNSLLKLNHKNTDAFEQIIALIHKCPFVPELKIELFVEYFANIYNNVKFSNSKESYLMAIRGLSALSSPLIVNKIQQILSVLKTTELSDLLDLLFPERDSDNWLFDMSVSRNVVSNLILRKILSDKLYKNFLNSRHLQRIATFAIENQEFFSELLIDANNFDAKIAEELIFQYFKHHPEKLIEIKKTVGYSEDEELKDKSILLQVLQIITLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTY8</accession>
    <name>A0AAD5TTY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001297">
        <property type="protein sequence ID" value="KAJ3204467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTY8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237:SF9">
        <property type="entry name" value="NEUROGUIDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13237">
        <property type="entry name" value="SOMETHING ABOUT SILENCING PROTEIN 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="211" mass="24363" checksum="0B7064C14DC0BB66" modified="2024-05-29" version="1">MNQKLNISCFFIINSKSLPTEHGVTLLEIKNHNLLSYITNLSYYLLLKLNGKKVEDENVISKLIELRVVLEKCKPLEAKLKYQLDKLIKMATMKEDLSLVHNYDGVIDEEEETQFKPNPLGLMKEVEKKSSAEFNDDKKAEIYKPPRIAPMHYNPDERDRTKLSQKMKQKAASSRLINELRKQYDSRPEEESAEGTGYGTKEKGNKLDGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUF0</accession>
    <name>A0AAD5TUF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arsenate reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001276</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001342">
        <property type="protein sequence ID" value="KAJ3204091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUF0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="ARSENATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041:SF4">
        <property type="entry name" value="ARSENATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13987" checksum="80F7C0EFE43D41D2" modified="2024-05-29" version="1">MNQLKYTLYFIPECSKCRGSLNLLEKFDENLLKKINYVENPPNEEELKKISSIIDGGFTSLLREDSLKNLQKENTEINLNRVLKLILNDPKSNLQRPIFINWEKNLAVVARPVEKINDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUT2</accession>
    <name>A0AAD5TUT2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-keto-steroid reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002072">
        <property type="protein sequence ID" value="KAJ3199623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUT2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000253">
        <property type="term" value="F:3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052834">
        <property type="entry name" value="3KSR/17beta-HSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44442">
        <property type="entry name" value="3-KETO-STEROID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44442:SF1">
        <property type="entry name" value="3-KETO-STEROID REDUCTASE_17-BETA-HYDROXYSTEROID DEHYDROGENASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="23074" checksum="B9E0CB92E51A7C2E" modified="2024-05-29" version="1">MQSVGDLNKHKLGATFCSNTFGHFIIFKEFENLLSPNSKVLWTSSTSADKEKFNRDDYQAIHTRYSYESSKRLVDLIALGNSVKYNQSTPVYTTSPGCVASNILQGLIPLWLHIFVLLVMRVFFGIKEINLEKSNSCSALMYLINSDKINNQELKYLSGSSRLGKGFVYLEHIEEKERDEAVKTLNLMEELYFEQKKHLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUZ8</accession>
    <name>A0AAD5TUZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Polysaccharide biosynthesis domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000763</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001193">
        <property type="protein sequence ID" value="KAJ3205575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUZ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045492">
        <property type="term" value="P:xylan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006514">
        <property type="entry name" value="IRX15/GXM/AGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31444">
        <property type="entry name" value="OS11G0490100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21729">
        <property type="entry name" value="IRX15_IRX15L_GXM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3205575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="24540" checksum="D5E2821F8FCA63EF" modified="2024-05-29" version="1">MLGFEIISETRKRNHQLMVVTEADSHNAQKVAFSYEIRRRKKNSLTDNQMLAIFTILKIYEYGKIDSGPKLLVFGLGHDALFWYKQYFMEPWLMDVPAEIKSECFDVVVIDGPTGNTMVDPGKMESAFFAVETAKNCILDNKLDFVYIFMHDCQRMTEKMIIDEYFWEGELIVKVHGDIGDLYGWKFDKKSIFDKTNSLKKQEKMKLNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVI8</accession>
    <name>A0AAD5TVI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000899">
        <property type="protein sequence ID" value="KAJ3210268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="485" mass="55247" checksum="BAAC3F5278CA5BA9" modified="2024-05-29" version="1">MNENVRESNFTEKDQNKYGLLKRANVIKKWKKLTNDDDDFKKPIEEATDYLIPNKNLKDENTILQTPNDYSNDKLNIENFLVPKINVTNTESKILRRSTERGRSRNNDFLEIKIKKKSRSRSKSNHRHHDISHNNGPPGYCLIKKKTELKSNLLKNDEPLVSALVELLKNDDMDSFNYKNILNLSEVQNIKKHDTLKRTKTLTKQKTTTLRQQDADESDKEYFNQNSISLEKQFTLKKQISVKHNRTLKKISTQRDLINPFQESSEDDDSEFFDARENLNNFTLKKKTTVKKNFRKQTRFLKDMDEKGCSLNSHLSNANIDAKLNIPTGQMKKSSDFDFSRRVTTIKKKITPLVIRKNNTIYRKVSILAMGDRLGKTTSGKVLSQGFGAVLESGIIAGGISVLASSIAVSASNLNPELQQKLLENMYIKGSLEYAEHIGNLKTYLPSSLQALAEAAGTIATVSGGLDAVEMEISEDDGDEDWDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVL1</accession>
    <name>A0AAD5TVL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Elongation complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001499</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ELP1/IKA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001423">
        <property type="protein sequence ID" value="KAJ3203479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVL1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056167">
        <property type="entry name" value="A-sol_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056164">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056165">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006849">
        <property type="entry name" value="Elp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23925">
        <property type="entry name" value="A-sol_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04762">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23797">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ELP1 first N-terminal beta-propeller" evidence="6">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 N-terminal second beta-propeller" evidence="7">
        <location>
            <begin position="256"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="8">
        <location>
            <begin position="549"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3203479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="696" mass="80298" checksum="A3ACBD4B84B87185" modified="2024-05-29" version="1" fragment="single">LEVVGTVDAGIEAMKWSPDLELNVILTKEKHLLLMTNDFNLINEVILVADVEGEDTPVVLGWGKKETQFHGSLGKQAAVEKQSKIHLSQNDDNLSRISWRGDGNFFCVNTILDEKRQVLIFNRDGVLQSKSEFVNEMEGVVSWKPSGNLIASCQKVGKRHDIIFFEKNGLRHGEFQLQEPETSKIREILWNSDSTILSILVERSGLKRSTVVLLYTTKNYHWYLSKEIQADKEGLLLDVFWDPENPLKLHLLTSTSVLLTPFKYKNTPPPMSHFKLQFPCNITHVSFFGSKEGDDLSILDCEQNLHLFKSAYPKEHLRLGSINLTADVANGDYIIRQCFLYEKNIIVAVCNSFEGDFFIFFYINFIEKDTKKIEIKGFEKVDFGLEIMNCFYIINHGFFFQGSDLNIYKVEKTDVYENILKAKFSEICDTFNVIELNYLNGEKELVILGLYRNKLFANGELLSTECISYFVHNDYVVLTTLTHTAKFISVVGLENFSKFKLEDSPSDITKYNENHRRIERGSKIVLATPCDISLIFQMPRGNLETVYPRAFVLSAVRNFLDQVDYKNAFALCRKHRIDMNLIFDYNPKQFFEVVDKGGFIQGGIDDPEYLNLFLSSLRNEDVTISMYRLSLLKHEKYKQKNKNLTKVDEICFAIRKNLQKLDKKNQIKFRTSILTTYVKQDLKDLESSLTMIKSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVL4</accession>
    <name>A0AAD5TVL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001684">
        <property type="protein sequence ID" value="KAJ3201709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="565" mass="65384" checksum="D9A32097718F8DFA" modified="2024-05-29" version="1">MENISNPAANIEVNDNTSELHTNNVSENSEGHTSISKRGILYESEEFKQVGILKRLNLGINEVHNFLIDVENNYILHFSHRDGFKSFIYKRLSKIMEKKKAEVFQEVLTTLNEVVQANTIGTFDDSGLQLLLPSANGNVQISVGVNNYDLVKPIAGLKIYNGFQCTICCNISRDTQKKPFYSENVKLMRIHIKTVHKRSDVQYSLCKVQKAFSNNKTPFKNICNSYFGVKVSGPEVSTNTPVARYSNFELMEILEKSGGFGIFTESQSNITAMHLNSKFFERSKFQNLFDSWPHKDLFRFVDKDDLEGHKFLIEKSVASYYNKVDTILKDTSLSHQFTSDLMILSKRQSMTNFRSLQNDSTKKVYQKYFAFFIMFCVRIQKKKHEELGNFFFCTLDVNTQQTLESFVLKLKDVQEKIAENNVDGNLFFQTPFGKNALKMLVSEVHKLHLSIMKQQFNKYESTFKKSIHCLFLMCRCIKVTIRNERGAEPYYFIKHDIDITNKIAILQHIMRMTLVFEIYEKQSMNEENIQYEFFLSLVNMQSEGINGVSKTSFSFLHELMKLATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVN1</accession>
    <name>A0AAD5TVN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002023">
        <property type="protein sequence ID" value="KAJ3199850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVN1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008506">
        <property type="term" value="F:sucrose:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432:SF26">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19432">
        <property type="entry name" value="SUGAR TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3199850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="166" mass="17991" checksum="E7C9C0D8735FD53E" modified="2024-05-29" version="1" fragment="single">MVTVDSSSSKFSIYLYCALLALPWIGVQTIWNTEFAVLSPTLKEFGLSDAISTLAWIAGPITGFFTAPFVGSYSDRSTFKFGRRRPFIILGLALTILFSLLFAFANNFGTAARLPVAFISFVCLDVTINIIQTPLRALGSDLAPQGYQETVQLFASVFQGLGGIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWS2</accession>
    <name>A0AAD5TWS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000781">
        <property type="protein sequence ID" value="KAJ3212370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWS2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="19071" checksum="322677489AE4C649" modified="2024-05-29" version="1">MVTKGSDFNNQLDLKLVILNSIVLFFDTIVFFMIIFNNFYASAWIMWNFFIHLSYYICTIIFFLFSLLNAINVAKNHVRLPPATSQTIVNFDGTTSTFTDITPIPEPLTLTMEQLLSLILVPFVPMVLDLIIIIVLMVYRKKLIRDNKPEVEKRQKEGNYSFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWU5</accession>
    <name>A0AAD5TWU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleolar complex protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NOC3L</name>
        <name evidence="7" type="ORF">HK099_007419</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000717">
        <property type="protein sequence ID" value="KAJ3213380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWU5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="6">
        <location>
            <begin position="42"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="615"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="615"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="625"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3213380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="826" mass="94621" checksum="4E34DF56F79E89E3" modified="2024-05-29" version="1" fragment="single">MSDSNSNYTTSKPIQVNSATGSNPLLTSNPGSNSSSTPGTPSKKSNRCAGDGCNERAVKIVGECKYCSLKYCGRHRLPEAHFCSNLGNCRQDSLEKLQNKLLKEKTVSERVQFLRNAEKVLRNPMRNSNLNLNANIEEEEEVHLSEDDFDIIKEYGSSLSFLSNLTEENLKKKTENLQPPLKQKKPVIETNIFGQENTDEEDELPNLTDSQSDDETSEESNNSTNNLKRKLDSILKSFSEDSESEFEKLDTIVSDADTEEELEDVDFEKHTYLPSKKKRKQNVESDEEIDVEAMAIKKDKWTKKVNSRLPIIDDEGNVLKVNQPLIVDRVEGDELIYIKEKEKKNLKQKQERLKKKFGKDFKIEDEETEKSEDEKMKVDLKNPVIQDNLKNLSNLEKQERLAEIASIISSDPEKNINLLKTLREFTKDNSNTIKKFAYITQLAVYKDIIPGYRIRQLSAKESTIAVSKEVKILRQYEESLLSNYQAYLQSIDKCIAENTKKNSKKENYKVDESLLIVAVRCLTELLQSVSHFNFRINILMAIVDRMSLKTPPEVSILCCNSISNLFDNDITGESSLEAVKLISKMLKQKNFNVTDEVLKTFLHLRLQSELHVEKNTEAEKQDKKTKNKNFNKKKKSPHISNSIRKVMKDYKEIEDEMKEAEAVVNKDEKKKLHLETLKLVFVTYFRILKHAKFSPLLPAVLEGLARFAHLISVDFFEDLLNVLKSISKQQLDDYLSNEVVVAKDKTFYDARSAFHSIVASFQLLSGQGESLNIDLKDFCEALYVQLLRLPCIAGESIIQKKNVEDNNELEYKKIKNRKSALDLAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXW1</accession>
    <name>A0AAD5TXW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000604">
        <property type="protein sequence ID" value="KAJ3214630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXW1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="entry name" value="CofD-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240:SF0">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="CofD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="713" mass="79684" checksum="A6292183899A1DF6" modified="2024-05-29" version="1" fragment="single">MNSPKPSVIVFSGGTAWNNFVGTLNSITSNVTYVLPISDDGTSLSSSSFYTSFLGGSTSEIVRMFGGPGIGDLRSRLIRLSRNKSSEDKAVLELLSHRLPQTQAEAIAEWEDILHCKHKLWRGITGFEKPFKHTILAFLLNFQKELTAKMTDTKEYQQNLNFNSQKINSVTQNKNSALSSKLYLFEDAMSDSTSLVPTYHAKFDFRHGSIGNFLLTGCRLFFKSLDSALFQIARILRCPNKTKVVPVISNVAQKRIRTTGIKTHIFILARRKSEPICDFDPENPSFGMPLLDSSITIIAASLRNGEKIVGQCEISHPGSAASENASDKRRASLAGMSPVGYMAEFEPGSRNSTTSKSSMSIKTSTSPATSLPNIDEQIENITTTLTDSGFDHGSCYRSPLLINIDQNTHSYSRDILISPVTNSQISPEKVTNDNLLYTTTTLTKNTNSASNLTSTTTSANLFFNKNKIAALNSPIRRVYYVNRKSQETLPKLNSLLPEHFEEKKSIIYACGSLYTSLLPSLIVEGIGSRIANDYEEEKVKILILNGTWDRETFGYTALDFILAITDALNYSCWAEEKLKSSSDDDTQSSPSCSSKYSPLRQSHIDLFDEKESFENNKSSSENFSQTSSIFVEDSPWDNLNEEFKKNENFENFESESGRTYVCFPYRPNRFITHLVYLDQGDIKVNVHRIEYLGITCIKISNSSKFYDESSLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXZ8</accession>
    <name>A0AAD5TXZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial import inner membrane translocase subunit TIM16</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial import inner membrane translocase subunit tim16</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">Presequence translocated-associated motor subunit PAM16</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PAM16</name>
        <name evidence="14" type="ORF">HK099_006392</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIM16/PAM16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000548">
        <property type="protein sequence ID" value="KAJ3215382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXZ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000006">
        <property type="entry name" value="Import inner membrane translocase subunit TIM16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005341">
        <property type="entry name" value="Tim16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12388">
        <property type="entry name" value="MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12388:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03656">
        <property type="entry name" value="Pam16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041978612" description="Mitochondrial import inner membrane translocase subunit TIM16" evidence="13">
        <location>
            <begin position="24"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3215382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="132" mass="14640" checksum="678B123222D58650" modified="2024-05-29" version="1">MTLPRVILQVVVVGTQIFAKAFAESYQAAVANSAKNAAQYAANKSADSATRKTGMTIDEAFQILNVQKTENPKDIDKDEIVKKYEILFKQNDPSTGGSFYLQSKIVRARERLELELNKGKEELNNNTSGEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY22</accession>
    <name>A0AAD5TY22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000891">
        <property type="protein sequence ID" value="KAJ3210428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY22"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="679" mass="80791" checksum="6086E6D577164492" modified="2024-05-29" version="1">MIKNHNNAPEYKKHSVKLTEEQYLLKLRKFSETVNLFSVGGAIALLDEMSFHNIPITDIHYNLLFKACLLNNDTLNTRNIFRKVLEQEKGTSNLQNNFKLQILNNDSLICLTQIFIKSFDYDYPYFGICLGLLMLRGVCESFISSSLLKHYQQQQLWEKYDQLENKIYFNPLFYYERDNEVLNYLTFSLGKRGEFFKIESLFEKLKAIHRMKISPELFNTYFLHLVRRKSKNYCLNVYNQYLSEGGEINSEIADSLMHLYGRSRDVDAMFSLFYTVDAKKMKVTDSLISTFLRYYTNIGGISKTLECFFGLVANNTFQPNDNTFKFLFEFLRLDQNINLTFDLFKYMKKIRYIPSWDIFNSLKHLVPKNKFEQQKLNYIFSSLQRINGSKNGGEFFFHLYPSINYSEHELKFVNFDSANQCDMKELTNNSVSNIPINNFSFAKKGYTYNLSTLEYDFVKFEDFEGSNALTFLEELKKPELYRSDIPIKLHKRLLILSESLTNQKNRNDIIYLLDTGKLRLTNSHQVRILLNIFLQDDSFDDAVRLLDILHKLNLTFSFREFDKLFKKLLYLKEFDTIKMVLRMQLKADLEGFSFTIFSTLFEVFNIDFINLKEVLDLFAFKVDLRFFEMGLDFYLRKALMEKDFEFTEFMLFWKFMFIEESIIPSPKCLLYLFKAWKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYF1</accession>
    <name>A0AAD5TYF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000489">
        <property type="protein sequence ID" value="KAJ3216233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYF1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="707" mass="78277" checksum="0C8903EF6F25AA34" modified="2024-05-29" version="1">MVQRRMSEEERIINIKSGNVFVWDEAESGIKRWTDGRSWSPSRSSGQFLVYKETEPRQRAVSVISDGHSDSGQTANSSPNANAAAGSEFVVKEDGLIKKTIKVETTLGRRQHLISYFTKSDYDKNAFITPSKTPHLSNSPLNLNIYSQFSEIDIGQNLNFTEPRAENNSITGSNFNNQKKIDFIPNSTHSNNLKQTTVNFSTNSYQPLSASQNSTPITPYTTSTRSIDQLPTKRSLLVVRMLEGQQEASSTDYDENIQNHSSENLETVGWASSQFLTPTNISNKKRKVFDDRNNRDIYKETATRSFNYEAESPLTYTNDSPLHRTDGYFNNKISITNSLLQNKTITPTAKFNRTLNEEFSNFNGLPSMSLSPSSLPSNSPQVSKMNAAKLNSGKGVSEKQGSSPNVGNPSSPYRTPVSAIHRQNLFMEDKGFSNLHPVERSYLPYNERETHPKTSSSLRFGMGSPILDQSSTTSKTEFSNPSSTVSERKSSIDVDSILRKDRVGSLSSVPEMLRRPSEHIDVRRRVSGLSPLILPESFSRKGSEKSVHRLSIVNTAFSTPIESATSAALQPVLEEGFLGIPQSTVKNNQTVINNWNSTKTNPSSFFTTATATNITEGNKTFANVISQQHEISSDLFIEKSASPDDKSVREILSTPALITPPTTLTPSTACSQILTPSNHSPNEVMSNSKKISVVNLIHKGEVNPMKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZC2</accession>
    <name>A0AAD5TZC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000413">
        <property type="protein sequence ID" value="KAJ3217729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZC2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="510" mass="55630" checksum="2EDD0A29A13FA470" modified="2024-05-29" version="1">MTRQHIAAHEWVCFDEENLRCEKPEKVNLAKGSKFYYAKLTCTDGKQLFGCQESKPASLPPKSEIKPSPGSPTSPTIPTIPTIPTIPTIPTIPTSPTSPTSPTSPTATLQGPPTTSLVTQYSPKTTAESTAAETYAPTEPYNLTCYVGESYDPTTIGAYTNFGQNQACLTAVSIFENKIYYSYDLVDSSSCELYANNMFYKNATCCESDFCNKIISTGDNEGTVSDNSTVPVGISCYVGSSNNLTAVSKVVTYENDGPNSCFTARRDNNTIFSYFSTTECNNYLNGAFEYYKDVTCCSEDGCNYPDGNYNIEPVSTITCFVGTDADLFFEALVTSYDEQTYSCVSAFDLKNKFWYYSYDLTSNCANYETGGSLSAYLANATCCDTDRCNDPSNNEPNSVVTTTVSSSVIPTVNDTSATTPTSIVSSLNPLPTQDPNSLTCYVGESRTESLYKYTKYGRNQSCLLATSLEMGVYYFSYDLIQTSECSSYAADSFYVSAKCCEIDLCNGLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZE5</accession>
    <name>A0AAD5TZE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SPARC- modular calcium-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SMAP2</name>
        <name evidence="4" type="ORF">HK099_007112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000663">
        <property type="protein sequence ID" value="KAJ3213944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZE5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF1">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="3">
        <location>
            <begin position="30"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="431" mass="46901" checksum="18435B0EA0692955" modified="2024-05-29" version="1">MSTRTTREAAKSTNEKHTQILKKLMQRPDNKNMGTHISKVKSADLDTWTPEQIENMVRWGNGKANYYWEHDLPKDFKLSESKVEQFIKNKYDRKQFALKGPLPDPDTIPLPDGVDQVNVATATKSISQNFTVPKINSSQKQEPSIQPAPNKPTTAVDDLFDAFQSAPPTTKPQEPANSKSSILSLYGNQNNGSPNSFGNFNLVNSQQTQQGFANFNQSLQNNQNFGNFNAMGNSMTPQSTSQQNFGDFNKTMQQTSQHQSVFGNLQFNSPSPTVGNNLNQQQLSGSMNNGNNPQQMGFGNTATSNIPVNTFSAFSSHISSSATPTKSAFDDLGDLFSSMKTSNSNNGNINNKAVNNFGTNVSAGIAASNGGANTQDMGFFQTLTPNQSITAQPVTQSNNNILDFSDFSGFSSSSASSKPVVTTSNDWGDFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZI7</accession>
    <name>A0AAD5TZI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peroxidase</fullName>
            <ecNumber evidence="12">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_005121</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="9 12">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="9">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the peroxidase family. Ligninase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000388">
        <property type="protein sequence ID" value="KAJ3218292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZI7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001621">
        <property type="entry name" value="Ligninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF66">
        <property type="entry name" value="CATALASE-PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00462">
        <property type="entry name" value="LIGNINASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 12" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="13">
        <location>
            <begin position="98"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="36"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601621-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3218292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="305" mass="33616" checksum="A3BE30F0DA70C9D4" modified="2024-05-29" version="1" fragment="single">KSKFPNIPGLKIEGKCDVNKWQKIKKQMVFLFDNECGELARSSVRLAFHDAANGEGGADGSILNFPLDPLNELTSGKNQNFNFINVTLVSIRKSFPEVSMADIIQFAGVLGTVLCPGGPRIPFVTNRIDATQKNDPSLLPGPSDSIATILAKNERAGLTKRELVALLGSHSCGKRFGASFIPDNNSAGLPFDSSPKSFDTKFYKEVLLPSPVVGTQRLPSDRLVATDESTKQDWLEFSENLTTFQKEFSDAFFKMGLLGQLHNTLADCTEILPKALNAGGNKDHWIPEKRKREFKGVFGDSWHKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZN2</accession>
    <name>A0AAD5TZN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004918</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000363">
        <property type="protein sequence ID" value="KAJ3218828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZN2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF6">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3218828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="308" mass="34311" checksum="854D617F39026195" modified="2024-05-29" version="1">MVYGLIFDNFPIFKKHDKPYMILSVVISTLGFLGLRFEFFSDTPASTALCFWLALMGMAMSDVIADSMVVKQARDAGLDGGANLQTFCWIMSSVGSIIGALLGGLYTFTGIINLVASFFFQEMKGDVTWSMSRVNEQIIKLLRAILLNKTVLVPMLWIILSAAAVPDVSSAMNFWKMMSLSNTGGSLSAFWGGHLMNALHIVKLPVDNNNTSALLMEEEYDFSQLPTALWIRVVGMIIPAFLALIMLPNTNVMEAYEEKNNAEFVELRNILFSEDLDNDSTLFDVKTSLEIIDEFDEIPLLSCKRQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZS3</accession>
    <name>A0AAD5TZS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006602</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000580">
        <property type="protein sequence ID" value="KAJ3214957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZS3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="244" mass="29235" checksum="72AF93840B4BD74E" modified="2024-05-29" version="1">MIIPIEIFDIIINYSDDIAIHIDFNRKYKTLKPWNMKFLKTIDDKMIEGDIEYIMKLNKARILVSLTNMIYYKLPFIIKFRCSKLLGINLIDSNTRCVLKYDTLMYYDRHDVINKLSMSAKDYVKTSDYHIYWKFEWNSEESCKAYRDYDYFMDYVQHTQGTYDYGFGYEPYEYSNIILLSNSIIFDDIEPFTFGCTGLKPSLIAKDSYNINDDDYYTGSHEDWIEEKINDEADCVKYCSRPYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZZ1</accession>
    <name>A0AAD5TZZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Subtilisin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_004953</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000368">
        <property type="protein sequence ID" value="KAJ3218706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042235940" description="Subtilisin" evidence="8">
        <location>
            <begin position="27"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="10">
        <location>
            <begin position="37"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="186"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="128"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3218706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="43816" checksum="63ADAAD61B5328C8" modified="2024-05-29" version="1">MLRRGFRQMNFLKPASLLLLLSTALAAPSATTGVENQYIIKLRSEVAALSGDVLDSHLSWLDEVLLKHADANSLLPGTKSAVLHKYGNLGSGFTGYALKASNAVLEEIRQNSQVEYVEADAIATAIGWPTPKPTTTSTATATSTKPASSTVTSTPTPGPSDVTWGLDRVDQRNLPLNSQYNPSGNGAGITVYVVDTGITAGHPQFEGRASEGAYFVENDAKDGNGHGTHCAGSVASKDYGVAKAAKVVGVKVLGANGSGSYSGVIAGINWVAQQATAGKSVASMSLGGGKSQAVDDAVNAAVAKNIPFAVAAGNSNGVDACNASPAGASGAFTVAASDKNDKKASFSDIGPCVEIVAPGVDITSTWINNGLKTISGTSMATPHVAGGFAALLSQQSFSSAQAAYDALLAKSTPGKITGLPANTANKLLYVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U014</accession>
    <name>A0AAD5U014_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000365">
        <property type="protein sequence ID" value="KAJ3218772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U014"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="278" mass="32385" checksum="1CC5B568B6B979D0" modified="2024-05-29" version="1">MSKQQLNKFLDKLMNCYTEEELASYQDGKGAQLKPELTHSGNNKSKEPKLEEFHEEKVKQPDLSVEQRLILLSVRENEMQNDWTKVKVPKYREWLEDYFKVYEAADTYRAILLKSSTKQTQSASQFYAYLFTTAATRFITILRTWHSSLSFPALRSIVQTFYQWPEEKSTILEKRTGMGSYTKFTEWMRAVNRKFVARPQTNAVASSRYPTSEHLKNLGRLTRYDPVFRSGVLSSRHDAAQWLIDNNVCLFHRILLSDCDAAGLAHSRYDFISATALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0H3</accession>
    <name>A0AAD5U0H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000485">
        <property type="protein sequence ID" value="KAJ3216300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0H3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="113" mass="14447" checksum="47CFED1E2D4147C4" modified="2024-05-29" version="1" fragment="single">KQYALMEWLERMVFQFVFYYLHRNLNKKEMYHELKREKNQKFEYFQDNLEDLHSNKVYIDPNKRDYTQMQRRKESELKRSRKIRERYQVATEEVVNYEITKKTLDKTKWNDYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Y3</accession>
    <name>A0AAD5U0Y3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mediator complex subunit 15 KIX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006624</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000586">
        <property type="protein sequence ID" value="KAJ3214873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Y3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.20">
        <property type="entry name" value="Coactivator CBP, KIX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036529">
        <property type="entry name" value="KIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036546">
        <property type="entry name" value="MED15_KIX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16987">
        <property type="entry name" value="KIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47040">
        <property type="entry name" value="Kix domain of CBP (creb binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mediator complex subunit 15 KIX" evidence="5">
        <location>
            <begin position="135"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3214873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="814" mass="90361" checksum="7F28B92B7C0CAF94" modified="2024-05-29" version="1">MNNNQNAQKTAQAMRLYQQQQLLNQQQGQFNLLSQQGQNAGGLTAQHVALLTLLQQQQNNNNANQLNFKNQNQQQTSAAQQQQLLQAIKQQQAQVHAQQSGSVNAFNNLQQTVDNQTQPTSNSNNNEVKQIELGITAQDRESVIARFVAVVNRVASQVDSSDRIQNLAKNVEKVLFEKATSKAMYTELVRQKHDSIQKKMSVNASQPNTQDNAAPLLNSGLNPTLNPTLNTSAGLNVLNSNLIANNPALANTLAMQPNSQFVFNGMQPNVAFRGNFTPEQTQLIQQFTPQQMLAFQTVLQQNPSNAQAALLRLAAQNQQNNQNSNQSATNFTIGQSSQPQMNQPHPAFPMQTQAQAVQPPACNFIQEIIPLLPKIETAIELIKNSGIDDKQDVKRRLAAIIASLGKMFKYAESCSNNSSALQTIANNSSNLGATNANFLNTPAAGFSVNLNYLQKQQQMQQQQQQLLILQQQQQQQQLAAQQQLAAQQQVLQLQSNNTSLPATTNVHPITQSLSSMANQQKKLKTEAIDLTSDNDADVSLKEVEKGEDSPQTPQDPSFQTLLTKAQINSLNTILGSLRPEDVDVVENCTGYSWTRDNTDFLVLGEDYNTEPLASCSDVPLDIIPDYFGDNDDSELFPEFEESQKSKSSENLNDMFSPLKKQFSESTFLNMETALNVDLEIQNLEKKFEGLKVTIEDLGKDEFFFETLEDGNNLPISVNFEFKTGEIIKLYLGTKKEYNFGLQNVTGIKFDMQEESAGFRGVQNIEVFGTVNKSSRFAEIAKKLQDNFHFNGSVLGFIKMTDVLNLIIKDSLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U120</accession>
    <name>A0AAD5U120_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Calnexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005822</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the calreticulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000471">
        <property type="protein sequence ID" value="KAJ3216565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U120"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.250.10:FF:000001">
        <property type="entry name" value="Calnexin homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000011">
        <property type="entry name" value="Probable calnexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073:SF1">
        <property type="entry name" value="CALNEXIN 14D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073">
        <property type="entry name" value="CALRETICULIN AND CALNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00803">
        <property type="entry name" value="CALRETICULIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00804">
        <property type="entry name" value="CALRETICULIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00805">
        <property type="entry name" value="CALRETICULIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041776883" description="Calnexin" evidence="9">
        <location>
            <begin position="19"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="255"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="545"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="331"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="572"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="157"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601580-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3216565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="67655" checksum="B51EB1962FD63C3B" modified="2024-05-29" version="1">MKLLVLLTALASTATVFAHEGQDHSHDVEDVDELDMDEDTIVAPPIEEDEVVQPLYKPSKVNGLFVEQFDGDTSRWVTSETKKIVDGVEDEDLLRYRGTWNVEEPVEWPGIRNDKALVVKTPAAHHAISAKFATPLDPKGKTLVVQYEVKFQKTHDCGGAYMKLLTHDPGFDATKFDDKSPFTIMFGPDKCGSNNKVHFIFRHKNPITGEYEEKHMNSPPQAKIEKKTGLYTLIVKPDNTFDLLINNEKVKSGNLLEDFTPPVNPPKQIDDPEDSKPSDWVDEEKIPDENAKKPDDWDEDAPMEIPDEDATKPSDWLDNEPSSIPDPDAEKPEDWDDEEDGDWQAPAVPNPKCESVGCGEWVRPTIKNPKYKGKWSVPFVDNPKYKGVWAPRKIDNPKYFEDKFPANFNKIGAIGYELWTMSDGISFDNIYVGYSVEDARKLSEEQWKVKYEVEKKFENKEKPVSQDSKNADSSENPYLTKLKDFIHQVQAEFEVIKQKWESEGPLETLKTFKYAFAGAFLVAYFLLSSFFKLIFGSSASPAGTEIKKLNKKNTKKEKDSDGEEEEEEEEVDEKKPEVVKKKPDSLNKRKKNTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U136</accession>
    <name>A0AAD5U136_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YdbS-like PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000420">
        <property type="protein sequence ID" value="KAJ3217593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U136"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="YdbS-like_PH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YdbS-like PH" evidence="2">
        <location>
            <begin position="63"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="204" mass="22399" checksum="0473F7DDC9A9251B" modified="2024-05-29" version="1">MSTNKVVEPAYNKFDNAYEIEFDHSKGSSKVGCSLCVGLCCTGLCIPCSPFGYFWGKKLMQNQTCTVDDYRINLKQGYFNKEDKMIPLDRIQDVNIKASWYSRLFGVSQIAIQTAGGMNPDGTPEGLLESVKDPKRVRDIIIGKRDKLVHEGAPGSSSSNGNGLDGGTFVNKQPSKTSDPSVLKELIAIKDVLHRMENNKNGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U169</accession>
    <name>A0AAD5U169_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tropomodulin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TMOD2</name>
        <name evidence="5" type="ORF">HK099_003803</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000254">
        <property type="protein sequence ID" value="KAJ3221065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U169"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005523">
        <property type="term" value="F:tropomyosin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051694">
        <property type="term" value="P:pointed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004934">
        <property type="entry name" value="TMOD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10901">
        <property type="entry name" value="TROPOMODULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10901:SF6">
        <property type="entry name" value="TROPOMODULIN, ISOFORM N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="422" mass="47053" checksum="A3909FFB912AEB87" modified="2024-05-29" version="1">MSIENQQNTETTTIETDNSDVLKVTIETVMDDTPNDVNIEKIVPVSDAAITHDLPEEEKMIDVAGEINFVQVDEIQSSKINGADVDNEKFVEKIDHAPEPTSKSNGADVNSEKVSEMESNKSTETIPLMESSEEKIGSHGEDFVEKIPNTLTAEEKVEPVSRIPVSKEKVNRRQTFQTLPKDTKFEYTEKAAPATLEDNRFLSKKFSFLRKNNHLPKEINIKKPLERTAADGPVVSQNEITAPVRATNPLLEEVLHAIDLLEQNDESLIELDLKDCPVFTEKIGTAIATALLKNDKLKKLNLANTGFNTLNSQQLAEALRENKGIEILNLEGNQIAPVGIRALADMLAYNNTLMELKLNQQRSPAGTDAEQSFAKALAKNETFIKLSLVIRDVASRNQIDRFISRNKDIARKKRNALKKLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1D9</accession>
    <name>A0AAD5U1D9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Transcriptional repressor general negative regulator of transcription subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">NOT4</name>
        <name evidence="17" type="ORF">HK099_003659</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000241">
        <property type="protein sequence ID" value="KAJ3221251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1D9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016071">
        <property type="term" value="P:mRNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010557">
        <property type="term" value="P:positive regulation of macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051254">
        <property type="term" value="P:positive regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16618">
        <property type="entry name" value="mRING-HC-C4C4_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12438">
        <property type="entry name" value="RRM_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000257">
        <property type="entry name" value="CCR4-NOT core complex subunit Not4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034261">
        <property type="entry name" value="CNOT4_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039780">
        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039515">
        <property type="entry name" value="NOT4_mRING-HC-C4C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14570">
        <property type="entry name" value="zf-RING_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="13"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="108"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="16">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="12">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="284"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="439"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="607"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="746"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="294"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="487"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="631"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="748"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="787"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3221251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1237" mass="138651" checksum="7CE7A08B87C5B8FC" modified="2024-05-29" version="1">MSEESEYDEEEDCPLCLEEFDETDKFFKPCPCGYQICRFCWNHINQDLNGLCPACRRPYSDEMIEFKPLTTEELFKIKAAKKKKNREKKEQELNNRKQLSNVRVVQKTLVYVLGLSPKVATEEVLRQHDYFGQYGKINKIVINRRGGNANAPMTALNNGVYITFARKEDAARAIDAVDGSVCDGRMIRATFGTTKYCSFFLKGQPCQNPGCQYLHEPGEEADTFLKDDGGKAIRNTAAKPSAFPVLGGGKRDDKEESALPATASWAKPTHQISHYVGVSAGSAVTSEERPTVLGGTNSASGESYENLPTDTEDSSAVVNSESTTDNNYSKANQGNYQISSATSTAAQINRTDEVEDYSTDANRTHITDPPVSVDDTENTLSLSEMGYNLVMKYNGLLNPFENIDFLNERNFLSNNNNFSGLSADSENNRWNDQYRQMQQMQQQQSNNKLRPSTTVNNYQANPRPMGREFMQEKGGQLLGRDFIEKMQQQQQQQQQQQQQQQQLYAQQPGMRINNMVSQPLQPSNQEEFLTQLLRSNLRGNPQAQLNSSTNEVTFGDPAIMSAKMGGNDIAGRVNFQNRAFQAGGEYAGFNGEWNEYEFADDANIATASTSSKATTSPNKKDIKELTKGGAPKSTTTKSSDTPPNLSLTNFPDLNSNININIKGHSNNLLWTNKNLNENYNNSHTTTNTNSIQQQIQKLQQIHEKEQLQLKEQKFQLKSEAEDSDNSVLLIHKDKKEEKLLKKIKAGSKVNTEKSIPQQNTTTTKDDKLNLASSKAAVSILQKETNEKNPTSKVDTDSGSPRLKKKSKSKLKTEKVKEGQPALVQEKNVPLDITGDLNVIESDFKESPPIFGKKLKKKKKGSGADLMATGIAATQVNSNSAPQRIAVKQLPQITEPAAVDIIEKRKEVNLATLENNLEVLLTILENFCVDENLEIFYSSIESSQLKSLLSSQVFGTREEFIDAALSNLVEIASKIYENIGETNIMEVNFCGNELESISSGLKVNMEKVIEKIINLEQFTNKYCKKDHNVNLEDFDIEECDPYTDDFVDVGRKEIEEFEENFNSNNVDFEQQLREQTMLQQYNSELMLEHEAAETDVTFDDADLTGVEINGEASTLEDRKLISNVDNLIAQLRQKKKIFKFGQNLNDAASSSDEECYEDFVDVLAVYNPEISLKFESLPQNTDDIATLERELRENQKKEKMLEKQFCQFAIANKTGISNNFILASGGELSQSTSSKNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1K9</accession>
    <name>A0AAD5U1K9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF885 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000227">
        <property type="protein sequence ID" value="KAJ3221491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1K9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361:SF2">
        <property type="entry name" value="DUF885 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="GLR0591 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="636" mass="72779" checksum="2A3768ED94C37F3A" modified="2024-05-29" version="1">MGFLKKIFGCTNSSENQKVKVLEKNITSHSVLSNNEVHPEKSTGDEILAEKSTNHEILSANQLSLVKDAQINSSPSLASSQLLLAIQDEFVDLKIKSDPVIGPVFGIKKYEDDIFNSSKEYLLKMQQFYLDLKFRLLNLDATTLSEAEVADLQFTKNAIITELLELEAYTYEIPSSHQHGPLDSIALEFEYYQPLESRQDIENYKKRLEKFLPRFNDIIDGFKEGVKNKITLPKESIDILIESVIKNVTENVSDSPFNRKEKALELTGDEKFLEETIEKYVNPAFKAVDTYLRTEYVHHARKYPGIYGLRDSEAVYQKLISIYTSVDYKPDELHQIGLAEVDRINKLKAVTQQEILPNSTIEEFQKAINNKELYPQLYFDDNNKIVGAYKSLLDKIDSITPKYFRSFPKFRQCAIEAVPENMEAGAPLAFYQAGTATKCGSFKANMLLHKDHPVLLMTAITLHEANPGHHHQLSLALETEGEHLIKKLVMVTSFVEGWGLYCEYLGEEMGLYEDKLQYYGRLELEMFRALRLVIDTGLHAKGWSVEKCLDFMKQYIITMSEAELLSEIKRYSSIPGQALAYKVGEIKIKEIRKFAESELGSKFNIIEFHEKLLSYGNIPLAALEMMMKKWVEDLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1R8</accession>
    <name>A0AAD5U1R8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003293</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000218">
        <property type="protein sequence ID" value="KAJ3221637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1R8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006626">
        <property type="term" value="P:protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14270">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051982">
        <property type="entry name" value="CiliaryAsmbly_MitoImport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45984">
        <property type="entry name" value="RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45984:SF1">
        <property type="entry name" value="SPAG1 AXONEMAL DYNEIN ASSEMBLY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="UBA" evidence="6">
        <location>
            <begin position="307"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="76"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="449"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="462"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="894" mass="101363" checksum="C761DB101E992726" modified="2024-05-29" version="1">MSSVNNDPFASLSSFNKKPQQQQQLNQLLTNKSDPNVSAKLANNVENKQHFIVMENSQTNTKTYAHLNVNSSLNNFNKSYSTNSPTSSTIQQQQQSNNNTYTQQPLSSFTYNSNSTVTSQPRNHFNANIVNNFGGNIPQIQQNKQVNSDLFFNQKQTQNLSQFSNLVNNNGGQLSNNHTNFNNSFLINENSHSIKNLSLNNSLMDHNPNQSNNWDLDYLSMNDNGLKTEAPFFNQAQMNKTNDNPEFDLLGDLSKPVSQFSKPDVAQKPDPNLIQEHSFNNASDSNLAEFGTTSTSVKKKPSVEIKENDRNLDKNLANLISMGFSRKEAVLALESTDYDIEKAVAILISQQNLLKSAIKPPNSPVSFRNRRVSFDSNSATKDYYQETTEKILTTATSFGKKLFSGAKVALETTKQKISTFTEDNSNNNFNEFGNISNFVEYENSTSRERFRDYSDDDSSFEETEKPAFVRRRFDDGSPSTYNHPGVEATSSSINPVRSPPQKPPSSRTVALNSEDLQEKKESAKKSLPQLEISTRQLSMLLNYKETGNKFFKNGNYASAEVSYTTGIQTLLSQFQNLENFQHTIVSQLFLNRASSRLKNGDYSGCVEDCTFIFNCFKEGGYSIEEQKKLLLKRSEALEKLEKFQQALEDYRSLISVGVNSNVVNDGLRRCLKSLDLKKVQEVSFSNIKQDSFDPFFSATSNNNNIFKNNFGIQQQSQQNPYVNSNSYDANFENNPFFVNDKNNSTVNVNTNNNIYQNQTQKPAMSKFVANKVNEAVQIHRQKNLEKENLEDLKLALKDAIDQRVDNWKKGKEDNLRALLSSLEMILWKDLNFLKINLNEIILPNQVKIKYMKSVAKIHPDKLSVDCTVEEKMIAERVFSALNFAWDKFKVQNGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1W7</accession>
    <name>A0AAD5U1W7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000210">
        <property type="protein sequence ID" value="KAJ3221761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1W7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070131">
        <property type="term" value="P:positive regulation of mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF1">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF155" evidence="2">
        <location>
            <begin position="55"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="279" mass="32016" checksum="C8EA996AD429CD16" modified="2024-05-29" version="1">MGELLSCLQKIFIILPFITDDVFHVRLSDPIDSSNTSNMELDSTKDNSVNFAEAFIFDNGTFATWGASHQEIEKLLKVVKQVEVNRYSSVETEWFSYCVDLSQPGGLIGDLLVIGHDLPQHQSKLAFSAGLTRSVKLASLEEQLDKHLNKHKHIPEILLKGKKLPLSRSKVLQNLGELFSLRGQVNLHSELLDSPDFCWSTTKMEDYFDRISRNLDVRPRIAICNKKLDYANELAEVLRNHLHEEHSIRLEWIIIILISVEIVFNVIEYCERHFNNKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1X2</accession>
    <name>A0AAD5U1X2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TATA element modulatory factor 1 TATA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000220">
        <property type="protein sequence ID" value="KAJ3221599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1X2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052602">
        <property type="entry name" value="Growth_transcription_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022091">
        <property type="entry name" value="TMF_TATA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46515:SF1">
        <property type="entry name" value="TATA ELEMENT MODULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46515">
        <property type="entry name" value="TATA ELEMENT MODULATORY FACTOR TMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12325">
        <property type="entry name" value="TMF_TATA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA element modulatory factor 1 TATA binding" evidence="2">
        <location>
            <begin position="865"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="493"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="764"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="870"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1079" mass="124056" checksum="628E62BC735F02E8" modified="2024-05-29" version="1">MSNWFNSGTADSWNSLLKQAVSTVESSIDKVLDIHNEKDASNTSLADALFGVSISEDLAISKQILSQQKIESDVECISTKILGKIVETKPLDFQPNEISNLTSKLNDVTGNFFGGLLTSECSSEDIVTQNGNNNLEKTKKSQSKFWMDIVLEPSSQKLLKRDETIEINENKKKQISLVNDEKDGFVDICMSLEVDMKNKTEAEKICALSQNNNQVIEENPIIDAEALFFNTADHHCDSKSGFFPTVLLNHMNQVDSSCEMSACEEKLTFDDVVANNKENFENAEDFAATEVTSPQIAGDSQSLKEVENLMEATNIFVNISESKNQHTMDSIHFNEKFDIYDNDIAINSNLYSAQLSENESLKKVICNLKKELFESEENLKKSLTLNQTLEIENINLKDSVGSFDNKIKKLENLESDANERVKDEFLKELHEKELVIINLKQSLSNSFVVTEEKTNQVAELLLEGDLNIRRNSFTNISKILLGENLSKQELKSREALKKQKLKLNEAETELKAMTLKFNNLQNEYSEVSKSLLEYKEKEKVNLASMKKFTEITDTHAKEISDLEKKCLLQKEKELQLQTTLDNVNNEFADAKIKFEETIAVAKREALDKEAESSTEIHKRLEDFQKNSENIISSLRREIIEVRSKLTRVEDESGWKEDMLRKELSSLQWKLQSSESRNEDMASSANDSTKPLLRQLESLQNQHNLAQKNWEAVEYRLSKKFAESETEKNETFSKYKLLKEKFNELNIAFNSNESILSEEKLRNYKVNLELKAVEEKLKIVELKNSELKLNFENLNIKHEAEIKQLIEMHQKNLKDRFEEEKKKKKTSKELSIKEKKIEENILEVEKKVVENTSEFNFIEKNFNKFEMEPAVQRYKSQISQLKTQLKMAIQTRDELADEIGTISNQIEEMKAKVYFLETEAKENSALKKRYLLSLEILGEKTEQVEELKNDILDIKNIFKLQINSLCVISGNEKSVLLLTKEGNLLSFSSEDRQPQSADNHLYHLHNANYLKEKEAKMNGIKISNLYYSNKDKLENSRNSEGLFFTYENGEKFFLMKIEKNLLLCIIGNNNSQFGMLSMKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U201</accession>
    <name>A0AAD5U201_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000305">
        <property type="protein sequence ID" value="KAJ3220424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U201"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="183" mass="21325" checksum="1FE8B7AE2D0996E5" modified="2024-05-29" version="1">MFRKTKKVCSKKKKKRSSGNRRSRIKDKSSKIKESNTELAQFLEEHSLTLSIKGRTGDRTVYDVYIYLKDAELFGVRTSHIHIIVKYNIIQNKTNRGMKIQVKGCITSSTVTLRIREDGERSVRDATRPECVPFNEQLDIAHFQEQVDVGKTTHIFWENVETFLAMIQNESESLLLNFKQRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2I9</accession>
    <name>A0AAD5U2I9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ras GEF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004338</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000300">
        <property type="protein sequence ID" value="KAJ3220461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2I9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019804">
        <property type="entry name" value="Ras_G-nucl-exch_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF356">
        <property type="entry name" value="FI05912P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00720">
        <property type="entry name" value="RASGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="499"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="696"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="986" mass="113293" checksum="F962D8ABF46E944A" modified="2024-05-29" version="1">MSNNTYLSIDANGMSKLESNSIYITENYETKTPPRRESTKDWLTRKMSLNTTKLSISSISNSSPTINESKSKKVDAGAYASSDELQPHQRKNTIPLSSSQHVRRPSSKPSTLILEEEDTLSLSSAPEMRPRSSSCSTNGKHKTVVDSKLTGSSKVTTPTEVKVEIEEMDYVEFLNGPTPKKAELSFIEFLKMEPPPDNKGNNNTSLPNLPQKDNISLSALKKKMSFSGSLKLDLNEKTNINPGNSASSINQLGGSNPSLSIFPSNMVNSPTASTVNFTAIKFKMSNLKYEKKSGLFVKIVLTVDNGVLSVSEEEEDSIDEVENNNQNLKQILKLQLGSLVSLINENDTENFGFIVVSADSKVYKFQAINEELMIKTVCVINTANSNEAYTKSLQVTNDQTKQYQSMNEFFKLINYCSLIDLEVYRNECKTLLERLGIKNLAEFTEDSSIEQEYQEFQQRFLIDETELISKMDQKFSNTEALIKSPSTNDIIRYEIGDKEKFLVCGATIEKLVERLSDEHGPDEEFCNIFLNTFRHFTSSEAFFDSLLNRLQTVNKEDNTDIEKENYQFRWRSIFKLRLILVFEKWLKNYWEVDFGFDFDEKNFMKNKKLAYQISKFLHLISVNPTDCTNKKYSQQDLMIFIPDLKFLKKSLKILILKFLRCDYKKSQESLEDLQTTLINLPPPKDEYNPLIFLEFESETVGKHLTLIQFNRLSQIKLIDILLNLWGDKSDLKIIKETSNLNDAINGFNIFSYWVPTTICTQPDIKIRVKVIEKFIKIAKSLQMMRNYETSFAIFSGLNVSSVTRLKNTWEIVDSKKKKTLNELEIFYNPQMNYRSYRQALEQIYLENEETLANTNESAGNGAVTIQPFIPIISVFLKDLTFMNDGNKKYLQENNQNKQQCMINFYKLKLIYQNCLKFLEFQSNNSVFNNNGNTSSNEINKILFDFCNNLRSLSNKEQVLHKYSLICEPKHDTQSSLALKWEEEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2X7</accession>
    <name>A0AAD5U2X7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002337</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000177">
        <property type="protein sequence ID" value="KAJ3222393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2X7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051186">
        <property type="entry name" value="RRM_HNRPC/RALY_subfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13968">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13968:SF26">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="150"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="302"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="661" mass="74020" checksum="B58C96ED48EC8707" modified="2024-05-29" version="1">MNSSFDLNKNQSSYIFNQQGQLETTCNYSLIPPIAPSAEKTSTSVMYQQNYQEQPQQQYAQDSNLNTSYYAFQNSLQNMSSQIGTGNEQAYYNEHAAYDANMYNEGIAPPHNNNYGQITKKPSSTKHYGKNSSRNDFNHKKSFPVYPPNSRLFIGNLNVESTSKEELQSIFSKYGTITEISLQSTFGFVQFETIESCDKAIQFEQGKKVGSSVWDLKYSKAKSRPYELRMAARDKASRGGNSDDREKKDWTRKDGDHDRSVRGGDRYRDEDRDSYKSRRRSRSPPPRKRSRSPDYHSSSHYKSSKKSSRSPPRRRSRSPAASQQSVRLYSLANSNVLNNFQNTMMKSIHLNGQIKAQEDLILPRKVGNQVADAQIICFSVDNFETSFLSQRFNPKSLVKQRMSEGVKAVFYLDRKGQRAKTVDFQIFHIDSTITEMSGITIEKSVRALERERDFQRAERQLPQLQNPMPTQNPFPVNSQNYQYPNSVAPNIQSSAPVDLLSLLNVLQSQQSGGFTGIPTSAGSSPMVGGSDLTSALLGLNRAHGSLQQQQLQQVPLTSNFSQSSGQLLQSSSTNLNSTSDSNQSVSDLLKRLQSVAGVVGNNNFSNSNSSPQLSQLNNYPSNPSHVLHNSAPSTTATVPNVASSMQQNNLLNLLQNFNSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U369</accession>
    <name>A0AAD5U369_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_001823</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000156">
        <property type="protein sequence ID" value="KAJ3222859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U369"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006862">
        <property type="term" value="P:nucleotide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044712">
        <property type="entry name" value="SLC25A32-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45683">
        <property type="entry name" value="MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="5"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="167"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="258" mass="28856" checksum="1046C760D15C667F" modified="2024-05-29" version="1">MVLISNAVDQAISGFIASFISTGILHPLDLIKTRFQVNESGRMKTYSTFMNIKQTEGLKTLYRGLSANLAGGTISWGLYFLLYEKFKENSKGVRQKNLNPTQHLICSAQAGALTSLFQIRKFEGTKGLYKGIVPGLFGVSHGAIQFMVYEELKILRKESYGKSTTKLSTLEYITFAASSKVFATVCTYPYQVIRARMQNEKSNTSHYNGLVKTVVRIFKNESFVGFYKGLGPNIIRVLPGTCITFGVYENCSKYFNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3D8</accession>
    <name>A0AAD5U3D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003588</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000236">
        <property type="protein sequence ID" value="KAJ3221328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3D8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="20143" checksum="6E821E9778374571" modified="2024-05-29" version="1">MIVIGGFGYLIPLVYIPTYAQFYLNVSKSHGALAISLFNFASTIGRILAGIFADKFFGRFNSFMGSFILSGISIIVLWGNSTSFAILIAFSITFGIIVGGVISLLPVVVADLFGLDVLANMMGICFSGYFFGNVLGPPIGGYFLDKFQNNGAINWLPTIALSASLMMLAGVMGIGIKIIEKKKKLNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3P3</accession>
    <name>A0AAD5U3P3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004036</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000276">
        <property type="protein sequence ID" value="KAJ3220746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3P3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="8"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="267" mass="30430" checksum="3B6803ECA689D0F0" modified="2024-05-29" version="1">MLSCSRYDISKSPLAAGTFSEVFKAKNKDTKEEVVIKSVLNDADSIKQAKNEIYLLNKLNHKNIVRLLDTFSHEDEKKILLVLEYTIGGDLFELISSKKLKSIEQKNIFKQLAEAVHYLHSSQIVHRDLKVENVLLSRKDIESHDAEDLVKVCDFGLAQEINEVNPRRGSVEYLAPELLLQKEDPSELDLYKTDTWALGVILFALLTGELPFNGSGNKMFLQIALGKYQLPESVVDEDVKDLLKKLLNTNPRERLSCHQILSHKWLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3P5</accession>
    <name>A0AAD5U3P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Intersectin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ITSN2_1</name>
        <name evidence="7" type="ORF">HK099_003098</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000208">
        <property type="protein sequence ID" value="KAJ3221804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035025">
        <property type="term" value="P:positive regulation of Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00029">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051480">
        <property type="entry name" value="Endocytic_GEF_Adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46006:SF6">
        <property type="entry name" value="INTERSECTIN-2 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46006">
        <property type="entry name" value="RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="6">
        <location>
            <begin position="459"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="DH" evidence="5">
        <location>
            <begin position="749"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1100"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1169"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1289"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1325"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="535"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1169"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1199"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1217"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1244"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1289"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1332"/>
            <end position="1355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1355" mass="154006" checksum="7C34DAEA93223178" modified="2024-05-29" version="1">MSIPNTTRQRVPSLKDNALMSQSFQPPTLGFNNVGSMESVQGSTQSLSYINEAGIDRSLPSKTRPYSLAMDHFKKMANSHEYLSFSTQREQNNRPISNLDYGSKQNLISDQFLTSPQPTLAINEFWQSIVRSKSSFSLKALTKFDNSNSNVKIQLKKESPMEKKLMRNASTRSRNSIGNNNFSDTAGFLKYIESSGFSGIWNHPVTRCYFIMFLIWAGFPSLFFFRQDVANYRQEFSKQSANSRKTAAFKIFNTYFGKKSSLLLILGRKCQTENLKFGIEAIKLNLENPDAHIFDDVALIVLKDLNEIYDSGICADFWMGDSIDSLPSSLSPDIPKFKLSAFYQMMQHDLRGTKHLTSVQYRRAAERLMDMPMDYIKDELISEKVSFYLESIGVDCENLNARFDANLKKDSRQGSNSKSTTENLPSSTKVIEIVKENGNLKDWKRMSSMQLQNIASITTHTFVQCNDLNICEYCYLQETKDSLYRCEVCGYISHKLCRSGVKVSCVMPSISFENDEEQLAISLNPEIENDPLTKIQYHNEKIRRVQEKINAIQKELDIELRISDGLNKIVSAKGNLKKGKKNAVDNDTVLQMESSVKKMEVLKHELQKCQVQLSSLHSSSPSEPELPLQIQTKVDDTDPSLNKDDVVKVVTIDPKTKSECTKAFFITSTTSVRCIITKALEKFVLKGTEEDYLLTYKCLEDEVPLRLEDLLMALSIDFSQVTLYLTQKDPAMMLTSSALQKDDPILIKKQLDVIAEIVETEFGYLDYLRFVVTSFYEPLVASGLLTKELSNKLFSNTVKILALHEKIVKKIMVGGKDDVTNIMTIYETEIDEFDIYKEYCANQSTSRRVLNKLKTDQLFSRALAQCESDPKLRKLSLSDLLVKPMHRITRYPLLIKRLLSYTRSNNYEYKVINNVINLFEEKVTEINETVRKTESCARINLIDENLDFNNICEKFKLVDGHRELLSEKNLTYIKKSTAGTIEVVVMLFTDLVLITRMKKQDQYQLLKLPLPFESVVFLDKLNSEQKKVFQIIHLQQEIHSLHAATAYDKNSWLQEAESLREKYCELCHDYELTRGYRYENCVSKLESKIPNSTRKLNGSNKGLSLIMDNSPGGSPKVMRRSYSSQFKSSKLEQEHSRVTASCDVNTFETGTQQVTPPLSKKNLWETSLEGTTHSHTSQGCGTETGFSLSDPYLSDDEQNSLGKFSNKTNSKVGFRYSGEHWETEKNSPKKNCSRDVFTNSISPQTNNSPLSVSSSVGSQTSPKSQTSIGSLENIPLGGKQKISIFRNRTTASDQSKPLAHSKSNSLGTNHLREWSGKHLQMVRKKIKNGGNNEEHANSVKESHLDRKSKSENELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Y6</accession>
    <name>A0AAD5U3Y6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_003824</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000257">
        <property type="protein sequence ID" value="KAJ3221018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Y6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000065">
        <property type="entry name" value="B-cell CLL/lymphoma 6, member B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF70">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3221018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="469" mass="51557" checksum="835D2978D444DE57" modified="2024-05-29" version="1">MSTCQCLCCWGDGCTPISIGSFISASESQCYVNACSANFAACNSSDDFTAWVIATFVPDTSGAYGAGGAGVLVIIGLLLYYFYRKNKQKTQNAVVPDVEAAAVPETEGEYFFYETDVNKDVIPIKVEVDDNGTPIKPTEAPSKPPSYSVSNGAPHMIFLKLTMIASVQDIHGYNTSSQPSNNLHHQSKSQQLQLPNNSQQLDTAASGLLSLSQHHKDNHTSNNLNGSSLQHQSNDQNVAADANAAAFALYYPQAQAALEIMARTNFSNIQAQASQQVQEHLQGQSQQKQKVHQVSPAPNNDINFENAITTVVDGKERYLCPTCNRAFSRMYNLKSHIRTHQNHKPFVCETCNLRFTRNHDLNRHSKIHSREKPHVCADCGRHFARRDALKRHERIDPEGKKLHCNPLATAAALSQGNQAQELSQYSDAVLGQAVQQIQQQMQAQLEAAAAQKLNLIVQADDLNCESNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Z3</accession>
    <name>A0AAD5U3Z3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000286">
        <property type="protein sequence ID" value="KAJ3220624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Z3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF57">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="5">
        <location>
            <begin position="26"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="226" mass="25981" checksum="2FCA7A28D00431E8" modified="2024-05-29" version="1">MAILKRAASGNIDPISIGVDPTTNSNSMIEVSTKLGYKTIASPSDFWYLDCGPQVPWCADKFDNNKPVWHSWKKMYDFNPTKSITNKEKVIGGEAALWSEAIKENSLDYVIWPRLAAVAERLWSKEEVILNERTEARLNRFRSSLINEIYINASITSNFEGKLDNYYRVEWCDFNLNSDSQKAIDSGYPGIVKNDSKEYYDYCETAKNYKTNSLKYSVPNRVEYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U465</accession>
    <name>A0AAD5U465_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000518</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000112">
        <property type="protein sequence ID" value="KAJ3223922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U465"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="74"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="485" mass="53903" checksum="8C574ACA828058C2" modified="2024-05-29" version="1">MDSSSSVTSSTKNSPNDNQIPILRKKQSLNRTSSISRVNCDSLASPAASFLSQIYDDTSQETYNFGPGDEIGAYVLHKEIGVGTFGTVFEARRESICNSATSPSVAVKVISRNSTSGSLSSSYSNSYNSKVVPNYDAMKLPSEEEIQNLVFQETFIWKQLSHPNILNLHDVVEADDNVFVISEIAKGGSLFHYLQKHPGGIPEKDAARLFRELVYALKYIHDLGIVHRDIKAENILLVDKLDESDNNSSISRGFDMNPVKKSVRSTVLHDAFNSPSSTIPSLTQQSSSSNPKGIWIANKENNNNNFPSSMNSSTPSSAISLTEPFQFEQTTDFLHNTDIEKFEVNFLETKRKSFAQDLDLNSYVCKLADFGLSAYIDDKDKKNSVVGSIHYCSPEEMRQQCFGQPSSDIWSLGVVLFAMVTGSLPFNDDYLPRLQQSIVNGRYDKSKLSKLSKNLQNLVASMLTVSREKRATMNDLLQDLWVLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4D5</accession>
    <name>A0AAD5U4D5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000292</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4D5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase subunit H/Rpb5 C-terminal" evidence="9">
        <location>
            <begin position="28"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="11">
        <location>
            <begin position="398"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="8">
        <location>
            <begin position="568"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="8">
        <location>
            <begin position="720"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="10">
        <location>
            <begin position="861"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1120" mass="129096" checksum="A10595A5E3B19342" modified="2024-05-29" version="1">MYAQSVSWSKIPPENHRKIILDKDPILIKHKLFKKHEKMSIEEFDTLGLDKSKLPKIYTNDLAARYCYAGVGDVVKIYRSDNKNDNRSYMSHIYILNYFTTPQVLHIITVVSPSSVDRSWTLTINALLLLHFIHISLLSIDLVNISSLRRLGCINFSLASGKCCNIFSMIDEFLLQFFHEYDVLGNIDKVYDNVPGMTSQCTFIQDDLEKNIFLVEVRLRSMHYKKDNRCSITFPKARYPLIVELSDNTFHVVTSPYKKSIPREQKTVRLSTLHADFLKIKEYIISAKYATIQEFETIETLLVSDLVGTGESIVDVHAIISKHVFGDKITKRVYIISLFVLCHQIYFRQNTDRDSYEYVEWMTPGKFALDYDERTFEILLKTGKITINNSVCEGISSVLSKRNGIDRLSSIRKIVIPIDENTDNLAIRSIHTSQKGYVCFSEISEGKTAGLSKHMAITCLVSPVFDSSELKYYLPLSSEPTSLIFIDGMCSTQFRSICRSQLKKIWKFIGVYYKDNSWYIRTTEGRPVRPMLHIETNEVHLVDPGEYIYHRHEYREINDQYIFGISSGLLPYVNHNQSARVVFASGMQKHMLPSISPKGYFNDYQQSLQTDIPIVTTQVHRTLMEYFGNNFGCYGRNCIVALTTFEGYNQEDAVVVNKKSVENGLFASIKYKRIIRDPTSIIYYDHKITGDIEKTAEKLLKDFRKNVQLIYHEDTGMHMEYRMLQIGDKIASRHAQKSIVGAIVDEGRLPYAIINGRKVVPDILINPHAIPSRMTIGQLMESNMSTNPRDGTAFRRHEPNTNNTYEMYNGETGIKIQRKITMGYVYYGALRQQVEDKYFARSGGPINYLSRQPLSGRSIGGGLRIGEMEIDALISHKAYNILNDVIEQSDKTTVRICTDCKRIVYGKSCKKDNHSTVEETVPTSYLISEQVISCLGVGQTKIINKYMTSMNGPSEYIFEYLYSTTKNYMEVNMLIDDILRRAKGYYISCKYCKRIARYEDQTCSMHSKTYQNDNIKKCDRPTLSGRPCQRKIAVDKVSCSQHMTSQEKYNDKLPEDNVPSQRTMFMLKKLQEKIDRGRPYYDPQNEVKKEKKKVECTPMPVDVDRLKSLITAYYDKYVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4J0</accession>
    <name>A0AAD5U4J0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000321</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probable zinc protease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000107">
        <property type="protein sequence ID" value="KAJ3224043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4J0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.70.10:FF:000003">
        <property type="entry name" value="Disintegrin and metalloproteinase domain-containing protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13574">
        <property type="entry name" value="Reprolysin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="620"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="8">
        <location>
            <begin position="213"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="7">
        <location>
            <begin position="431"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="657"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="663"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00056552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00074021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="723" mass="78356" checksum="8DC3DBF914DD330D" modified="2024-05-29" version="1">MFELERNEQLIIHDSTLHLHDNLTNQKKLYPIIAYPYKGSVKNSESKTLGKARILFHQNPLVETNSQLLYEGSFTNLDGTYHISLVRNYRNSRRPGLDINLASPYERESQHKNAHLILFKDSINESSHKPTALFPPSELSQQYGCGFEPSNVNEVATNEFRGSPELYSHILRKRQSSSNASSCKLTSKKVLPMGVAADCTYTAGKPKLALNNIISNWNQVSEVYESNFNIQLAIIEVKIMQSCGDGKDGEKLPWNIPCSLNFTINQRLSAFSSWRGLKTGDIAGLWHLMTRCNTGPSVGVAWLSTVCLNKTQSQFENGEKMTVSGTGVSSSVPVEWKVVAHEIGHNFGAIHDCMAETCPSNCPENSFSTQCSCCSCSPTCDCNGNFLMHPTDDTASNSFSPCSLRYMCANLDIPSHQKCLVNPGELKTIAAGICGNGVVEGNEECDCGSGCATDNCCDETTCKFKNGATCDQLNDDCCSNCQIKEAGGVCRSSNDFCTKEQTCDGKSATCGTSVVVPDGTPCSTKGNETGTTCASGICTSRNLQCQSLGTSGFKTVGPCPGQDDACSLLCATSKGVCLMVNGNFIDGTPCSGGGFCKNGACIGGNFIDQSMDYFKTQPTLAYPIAIAIGLVALAIIWSILRSLFGCLKNCTRRSSTASRGRTVNNRQSNNQPVGRNDSVTNWVDPSLYNGFSSEPPADIYISSIHSRQQYQQPQHSPNHIPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U549</accession>
    <name>A0AAD5U549_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Pre-mRNA-processing factor 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001323</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000136">
        <property type="protein sequence ID" value="KAJ3223282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U549"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000256">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013875">
        <property type="entry name" value="Pam17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010491">
        <property type="entry name" value="PRP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08566">
        <property type="entry name" value="Pam17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06424">
        <property type="entry name" value="PRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PRP1 splicing factor N-terminal" evidence="10">
        <location>
            <begin position="161"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Suppressor of forked" evidence="9">
        <location>
            <begin position="467"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="967"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="163"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="242"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1069" mass="121185" checksum="CE8757C13C751B09" modified="2024-05-29" version="1">MSHALKGKLLPWKEYFRLKKNVKNAERTLGIIGGGTALISSSYYFGAVADFDPVEKVFGMIDPQVAFPIATLAIGSMGWMFGKVLGGSIWRLCQNRHVLKCIDAMDTDFYHRIQHHRPKNINTSLQIVPDYYGEKINSVQDYRSWLKKQKEWHRDWLTKQAPPNYVAGLGRGANGFTTRSDIGPAREQEATPGLPAAPEAPLPLPEKDNKDDGEDDDERFQDPDNETGLFNSLPYDDDDNEADSIYKQIDDAMDERRRARREEREKEELQRFRKERPKIQSQFSDLKRQLGDMTSEDWANIPEVGDLVRKKGKSNKNNKNNDRFTPVPDSVLLSAQRQNQQYANTIDANAGVDTPMDGTTTSTDFAEFGQARDKVLSLKLDQIKDSVSSSTVDPKGYLTDLNSVIIKTDAEISDIKKARSLLRSVILTNPKHAPGWIAAARLEEVAGKIVQARELIAKGCEECTKSEDIWLEAARLNTLENARIILANAVRSLPQSVNIWIKAAELESETNRKKQVTRRALEFIPNSVKIWKAAISLEDDPEDAKVLLSRATECVPLSIELWLALAKLETYQNARRILNKARGINQTSHEIWIAAARLEEKHGDPDKVDMIIKTGVKTLVGLGSKLDREQWIKEAENCEKNDSLITCQAIIKATIGIGVENEDRESTWMEDAESCAKRQMFATARAIYAFAISNFPKEESVWMQAAFFERAHGTRESLETILQKAVQNCPHAETLWLMGAKEKWLSGDINGARGILEEAYSANQSSEDIWLAVIKLEVETGNFKEGREFLEKAREKTNSRKVWMKSAMLERQLGNFDVALKLLDEALVKFPSFEKLWMIKGQIQDIELNDLASARQTYANAVKQCPRCITLWILSSRLEEKAGVLIKGRAILEKSRLINKNEPELWLEAIHLELRGKHPSMAKALLAKALQDCPNSGKLWAEAILLEARVQRKAKATDAIRGREEDPYIILTIARLFWAERKIDKARSWFQRAVKSDPNIGDHWAWYIKFEIQHGDDQKRKAALEQFKNADPKHGEKWQAVRKDLKNFGQTLEKSLDIVVGMLDDKLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5A1</accession>
    <name>A0AAD5U5A1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase epsilon subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">DNA polymerase II subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007907</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5A1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008623">
        <property type="term" value="C:CHRAC"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22928">
        <property type="entry name" value="HFD_POLE3_DPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051377">
        <property type="entry name" value="DNA_Pol-Epsilon_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172:SF1">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="6">
        <location>
            <begin position="63"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="146"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="210" mass="24119" checksum="C0522D66FFF27FA4" modified="2024-05-29" version="1">MTETNVERQKSKKQKKGKLGSSTTTNAKKKGQTTNKKNQKKVDLEPPSHEEEYQCVGLDDLDMPKNIINKILKNGDTVTAMTKVCTVFINYLTATANDISRQSNQKTLMVQHLKKALEILELEELIPKIDENFQKFKEFSLLKKSKKKNKEVNDSENKDKTEESKHSEDGEDPNGVDLKRKREKEEEEVDDDKDSVDDEVKSLLDKMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5G8</accession>
    <name>A0AAD5U5G8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dipeptidase</fullName>
            <ecNumber evidence="1">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000127">
        <property type="protein sequence ID" value="KAJ3223503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5G8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041782926" description="Dipeptidase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="509" mass="56857" checksum="E499B88DF7E48DD1" modified="2024-05-29" version="1">MIFISSIIVVSAALCQISSAPANSPLLSGFADLHVHQMAEFAFRRAWFAKGANGGYSHKGKIEDALHQCNGGFNEQHAGTIFGPLIDKEIGPDAGLHLEKRWGVPDNDCDRGKPNWYQKLLGLCKVDKNLSGFPIYTTYTHQQVWEGYLKTAHDSGLTLMVMSAVNYKPLCKIMATSGIDNDPTLACDGMVSIKRQFDEAKIFCTERKWCQVVYSPEDARNVIAAGRMAVLLSIELSHIFEDSHDAIGAQVDYWYDQGMRVVQIAHEEDNIFAGVNPTNPIFKFFQAVEAITHINPSKWPEVGEDGLNKKGLTEKGVALVNKLMEKGIIIDVAHLSFRSTEDIFQIGVEKSYYPFIQSHGSFGHNDYSEERYLTDWMSLYLKKSGGMLGSMTRNVIKNYEYSFQLGINIAFGSDLNGFAKQLAPNATFQDKELREKGFAHMGLYPGLKKEIEYVSLDKGGSILHRSTENVVQLWERCLNNKRKMLSTEGFNPSNKFSASPRGVFNASQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5N1</accession>
    <name>A0AAD5U5N1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007344</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000070">
        <property type="protein sequence ID" value="KAJ3225139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5N1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="281" mass="31352" checksum="F100A822C92CD2A0" modified="2024-05-29" version="1">MKEIYTLGNLLAEYTKGLSLGFGLALILTTALFHRNSNRYTKLLAYVIGFSVALQAIWSISYDVLLLPACNLKVKVCCVLLYCEAVAYWLLQLKAAHGLNKKMPKIKVILGTAFLIRFGIMISTLNAYSGILQPNGTCATYLPLTFGIIDQTAEMLYSLLMTGLFLLSVNKYRNVGKSENVKIGIIECKKCNNKNRTEKIENILVLLSEQEIVLVFSLLFNILYDLFVFTQNDSLRISIGHNIVNKKKISTDTMTSSQKSYGCSSKSTTSASLKYEEDSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Y1</accession>
    <name>A0AAD5U5Y1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002132</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000169">
        <property type="protein sequence ID" value="KAJ3222578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Y1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="198" mass="22620" checksum="7E2BE41C94D1E05F" modified="2024-05-29" version="1">MEFVFLDAPHVVTKKVASKFYRDLVGEDIYTKDIEEQLIPCGRIMRSWLNSDWDVQESLIYLKKVLEKEEVFDGVLGFSQGTIIGTLLIAILENPSINLNLKNINDCKPIKFSIMVCGLKKIDSFCTNIYSNAIHCQSLHLIAKDDNVVSNKYSVKLLNCYKNSATHYFDFGHAIPSDEKTLNVIKHFVDSFYIKSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6I4</accession>
    <name>A0AAD5U6I4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein tyrosine phosphatase, non-receptor type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PTPN12</name>
        <name evidence="5" type="ORF">HK099_005337</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6I4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF449">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="174"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="626"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="591"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="483"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="714" mass="81662" checksum="15CC7B5F6AD2CA07" modified="2024-05-29" version="1">MGNKLDKLTRTVSGRSLQNENHSEEETKIENSNPHQKNTVENTKIRSSSAFNDNLSSIDTENAIKTQKINRNLQPSINVTNNNQSSSPINATGMFIQRQSIQNRRASDHKKLLSPRNTLKLDTTPFLSPTSVSPISPSLSKNIYLIAEKINLSTLPKWLYRIIHLSNNQTLSQLYSEVKNAQKHRIMSPQLSYLYSTSVALQPKNLKKNRYTDILPFDKNRVILDTSRFPISPNDSNRTDYINASYINSGNDCRYIATQGPLENTVADFWQMIWQENSRVIVMLASEYESGKHKVFKYWPSQKGDLILRVFTIEYLKGSAMERRRVWHIHFLGWPDYKKTSSRNLLTAINLMNYLNFRVEIEEELNIPSGSLEFLKIQRFGRQGRSLNLRSFLKEVSDESFHDLKIKFGEGVFNLISKKSIEMLLLDDSEQECTKNSAADNFSANGLSSEHSSPSTVEFSNLNKKTNYTSNLRFTSDRHIDPSSKSNDSFAPNSPPVNFEIYSTPMELETFKTPVAANNFMSMNSSNTNISNKSGIENFHSCENTLDYKNNNMEVDDTSYQQDCQQNNISLSNSEAINGLGLEFEKKELRMEPKKQRSQLFQNNASDDEEEQLNRSRNMAKIGPPVIHCSAGCGRTGTLITIDTIETLLTSQAPGAEINRSGNQDMILEIVDLLREQRVNMVQSFEQFCFCYEAILERILEWQESDKSFEWQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U708</accession>
    <name>A0AAD5U708_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000030">
        <property type="protein sequence ID" value="KAJ3226709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U708"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1024" mass="118687" checksum="964FF1E54D08203B" modified="2024-05-29" version="1">MNAHSHVQLSPICYTHTEVNSIDKFSVTKNYELSNNERGVKGKRLTFTENTSPDLKEEFKYMDSFIGKNQQKKKLVSILSRANNRKLEKLTTEVDTGNSEQNLSLKEVHAETNNLPPAAESSEFSITKAANKKLFDNGVVSLIFDYSIYTNLNVDQHVIRLPTEVAYISSTIKHIHKCSELFREGKLGYIKLSEISKDSFNEIINFLRYTNDKSCAIPIDENLPLNESFKLSCPTKELIQLVKHADYLNLPNLVELCTQEIKSNFTDYSLLADIPEEILLKILEKMTIPNLFITECSMLENLKLDEALKRNFFKVNCDRIWEKNFQKICMAKLKTIDRKYGYCSKIKEITFDTLKNSKLQCLEFYFNQLFNCKVKISNFDLEKAIFKIFDLILIYFKESFKITRLKLNLNFFNSFFVNEKRSELELEKVLNLITNLLNFKMITENFIFIFAHTTDGLNNNLQYLKIFENSKFLKILELRNVNFVFEIKHHPFENEIKQICLNLNDGKDLSFEQVFFPLVEEIGNVTFNQFSDIPFTMDCLPKEIGKRTATHKLNSRLITTNNLLEPIEKNFNEKVKVLKFSNTKNKVNSKEGLKMNEVLYLLKTVFSEKIAIDSLNLNSFGLPWANIYLSKILRHKRQLVAKKSSSLNSNCYINLKLLNISRSYFGGKGLSGLIKSLSTFNLLNLCKLDLSFSILCKDIGSNELCHSLKDFLKTTENLEFLNLSGNYFTTYGFNLILDGIVVNSSLLNLDFSFLDLRTTYERLSVVLSQRKIKRTFCREAINGLKSLILRDCQLLPRMITIFVANLFENDFPLHKSNCISKKSDFQEALGIPNEGKISRIDKFDLSCNNFDGTVAASFRRSLVNVTIREFLMEGSEDKIKLGDDSGCEMLMILKNLNSLKKINLNNQSLGKKCWNILPYILYETKDLTEFKLKKNHFSEQDLSNLKRNLKNASVKMKDNFKDISLFKQKGEFFFDFGMFHKRNEHKVFYPGEDTFNTGSAEYRFELWKADKINYEDSNGYGYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U752</accession>
    <name>A0AAD5U752_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001262</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000134">
        <property type="protein sequence ID" value="KAJ3223340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U752"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046956">
        <property type="entry name" value="RLP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48063">
        <property type="entry name" value="LRR RECEPTOR-LIKE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48063:SF90">
        <property type="entry name" value="OS11G0565920 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="298" mass="32831" checksum="4EAA0FE5C635ACA7" modified="2024-05-29" version="1">MEWQPQLFNRTEDCCFRKPKYNDTVAIGCDFERRISTLNIGTLYSPLPRVRAIPTTKAFLNVEVPQFLGEFDKLTTLYMAGLNLRGQFPNSIKNLTNLQFVSFKSNLLTGVLDDDLFLNMKNLVSLDLGENKLSGNIPSSLSGLTNLHSLGLNSNLFTGPLPDLTKIPNLGVGQVDRASGGFNSFCYLNGLGPMQGINQGICLQDDGVIPATCTAPRLPYCSGKLPGTNNGTTTEPRKKVIIIRKKGLDFFSIAGIVIGISTFAALIIFFSIFYFCINKNNIKNVTNKDIEISQEKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U764</accession>
    <name>A0AAD5U764_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000025">
        <property type="protein sequence ID" value="KAJ3226964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U764"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="352" mass="40398" checksum="9A4B81455611049D" modified="2024-05-29" version="1">MKDRLSDSSFNSSTSSASSQPWIPCGKIHHEPHPVDTVPILKSSSSLNHTNNINTNSKVWLPTSKVVETNKPLFLINDGCKNVKEKGSKNYNNENIRYEEVEIIEEIIEYEEVPDVLNWTEGVKPEVNATANYIDNHILSVKGFDRAHALVSYFLHREEMRQLFADRPLAGIFAQDVDLTPDPWGQSERPKQTVEPLIHHLRDQIKAIKNGGFGTMSFHEKKENSLTDVVDFETLGEQLNLFTKKETHKLIQEVLSPKFEGKSVIICWYLNLKVILNYLNRAHQELPKLARFLGATEDLSVPQKWGKRFDVTWVLMHNRDGVKFLQYPQRLLFGDKNSVIGEDESDEFSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7D1</accession>
    <name>A0AAD5U7D1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD repeat-containing protein 27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">WDR27</name>
        <name evidence="1" type="ORF">HK099_002918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7D1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042411">
        <property type="entry name" value="WDR27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44525">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44525:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="990" mass="110763" checksum="8CFDC7CB6A7EC2C7" modified="2024-05-29" version="1">MSSNNNSSFALEIGPQFSANKAFTCKGDWILLLSQKKSIQFFNLTNNISIEFDINASQKSRLIQFGNKFNPFTLILCTKDSVTSYKFKQAFDFDLELVEERLIASDIGKVSFIALDQNDCFVAVSVLNKVYIFDLINNFTTILEGHGGNVTVWDIMKKTCIYQSSIISAHPFTAIDIDPRQDRNKFCLGSEDGYLRFYDYSQKTSINSSIEPRLLTVISDLEVQISKEPSIQSSVNIINSVSSWRQSEQQQKSIKKLNENKDVCMNVNHSPSVLTLHYTPSRNNCRLIVGFSKKLLVLNVDNYQILFRFEFGEQTKTVALAAEPLNFEIKREEIIENNFNMLPLVGTFGFSFSEKNENVLYIATKSCLSKEVNILKLTESFVLGDKSNFLPSISYNEKLLIPCKGESLSHYLERLISTQVKGNWAENILKDCLLKLNSFNINSITAIRNNSDFLNVLNKIEGLPSFVLKNLENICLGGENVTFDSKFSKTKVDFITALDMPLNTESPLHYVKNKPNIRSSKAVMTKCGFVSKKQLGSLNQPITFRSKVKSSGYSASPAVNKLFTKPKISKRASQTSISPASFSESNLVHKYELLNTDTRLILSEFNVQPHAAPVVCLKYHSLGNFFASSSVDKTARTYLTRKNSSVKTFIGHSSGVTEVAVGERCIKNLGYPILTLEGGNSLVRFWGTEKSDPLILIGAKPKPVKPKPKTENTFYRIQGIKFFNHDELLVFARGPILQFATYNIHKPDPGSIQPNMNSLYNSCKVVGQYSTEADNILSKPSITSIACMNTVNSHLVIYATSDKKLSLFDVNAGKNISYLENAMKRAINNIALADYYSISNYFHPEMEREGSDEEIESLSVELNNNFKIGLGVGNSGFHNMFSTSAISDSIKLWDLRNFQPVLHLHGHINRLGSVGASLSPCGRFVLTGSEDNQAYIYDIRKASVLCKLSGGHNDIVSAVDFNPINAEVITGVSVFNYYVKLNDVGTRWKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7M4</accession>
    <name>A0AAD5U7M4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002156</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000017">
        <property type="protein sequence ID" value="KAJ3227405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7M4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038:SF1">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="95"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="203" mass="23660" checksum="48A0C9806DD96F7A" modified="2024-05-29" version="1">MALFVGKVPDKFSRSDLEDIFTKYGKIHRCDVKRGPASNYGFVEFDDKRDAEDAMEGVDGKTIDGSRLVVEWAKGAAKKSDNKCFNCGREGHWARDCRESRRDGRDRYNSRRSRSRSRSPYRRRRDYSRSRSRSPRRRSRSRTPPRRRDSRSPPPRRRDSRSPPPRRRDSRSPPPRKSSVSPRKDSRSPPPKASSRSPRGRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Q9</accession>
    <name>A0AAD5U7Q9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Q9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="689" mass="79366" checksum="EE1EF27D15EFD6D6" modified="2024-05-29" version="1">MQKNICRCLWESCYASFETENDAFEHTIKSHAILGKQVCCWIANPSLGRCNLTIKHKGHFKDHLVTHFSLLLRPFVCVHCSKLLRNRQQLSRHTRIFCEAVKPHVIKSESKKCEQIVSHDKLTNATPILIRKDLPFSLPQEVPYRVTADLRFNVTKEVPLNVVNEVNCKISQEKTFQISQDPSFRLMSCDDSSNTSSDVVTSDISLSRTSNISMSNEPEDDFDVSDFQPLTDNSTVHEVDNRMEATFYLEDQECFIEESHNCYQNTCYHSTDVKKNLNFPKTEMSDDVVYQSSSNVNQTPVNVVEGVYQTINVNENLFQKTINVDEVANNNNSNENQMVVMKGKEVETHSEPTTSVLPVTISPNDIFYQVNSLERLCKTFLRNSGNAILRFTTVPCPQGWNVGIICNSFANEFNIEIPEEYKEVVAKTHKFTATANEPTYIDVKYVVDLANRIGRLNLTEVAVNKYIENQHHCKIKSKYGFLIERLVNTLSFQLDAKLKILSKEGLLMEQNIKKNFLPVIKKISSVRRLLLIITKVIRLTIMKYISNVDQIDILEPTPSNQFFRNCYDCTGSALIIHYNIKLTMNPLMLKLRKSSFKNLADIFKLEINNLVKDLIYGKYREDCLKLCCFGLLCQNNIEIKNATRFNLNYFEDDTRFYFLLRLGNDLSFIFKEPNFANCVNELNLRNVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8D9</accession>
    <name>A0AAD5U8D9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="1252"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1151"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1443"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1154"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1443"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1480"/>
            <end position="1499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1542" mass="171312" checksum="91263FE84295D37A" modified="2024-05-29" version="1">MSKVSSLKKLFEEKAKADSVKLENRNLSNTPSYYSLKSNSKSIDSMKSTSSLESTQSGKKEVSQCGNNTTVVDFKNANGLNEEKTSTNLLTEEAAMSSTATLVNEIEDLIKIEENVLIQRLENGNSMVDAVLETAEPSPYLFNEKQFSNTANNNDYNDIPLSMNSLSEIVIQEGNKSAFNECSKVEYDTQEKKFSDDTEVMSKNCTNDDIGNDLSREASIIQCDNFIDSPTGVNGISETYYHEESDNRNLQCNTFIVKGNDDDNSTKINELLETTIPDENNSESERSIVKINVIQENVIESKETCFIQSETDFVQCDKSLNQSTIKAGTGKDEDLLNNANINYVQDEVSNLEATVAENSIKGIDSSFSEPLNNIIIVSDCKLSSDFHSPENTQEETVEKLFHTNESTAELLEVRNVEKEDCIVKNFDKSIENKQDAENCLNSNEIYANATQDDFHFAKKVDILNNQPDVVKGFSKLPESVRLVENIERITDVDQENMEQCTKIFDNEDANVMESELPENSKGFENDELPLTNTLFRVDADLQKNKNLEVIARECHTKLIENKLEEVNGYMENEVSKTENNVVNAADESQALLCDIEISKTDTVDLDAADDTLPLAVDEISKTEIVAVNAADDSQALVSDIEVSKTENGGLEAADDSKTLSSDVGNVDLCTVDDQLPQTLDEFSKIGNASDDNATLQNSENNLTLCSADGNEVNAEIWYSTLKSVIATVDLEKIEISKDSIPPSVVEPNRKIEILNEHKLLEDSSKSTLKLNTEVCYEPVDLFSEYCSENEEDEEKFSPKSEVGTFGPKSAVILNEISEFVACIEEETENVDSISIVDSEESTGYDILGNYMNTGYEEYEENEENAEKIISKKSSTAEMDKEGFEVPKKKLSNPSLINKENIEKLKSTLTDIKALKGIRLDTKYDSGLEHIPFSDEEEEFDPPSLPPPNVPLPSIPNERPTAISDIQVSESLLEIYNTQSFEEKSINHSIYLGYNNDSTENFFSSYEKDLDEFDPENLEKVGVENILLDELDDCMDKLLLDFAELEVEVNSESNSLKNDSDSIKKEDISSDKALKTLGIKDDDALVNTVHTTFSQNRIESIPKALRTLGVIPSNLVKSQHLVNDDSDSSSLVNRRNTSSTKALKTLGIIATPMRSPLTSPSSPISPLATPSPRDRKGKGSNAKALKMLGITDSLPSSASPSRVSTYSYDASVGFLKEDSNSSPRNSIVSTTGSTDLQLTSSTKVVKLGSLKEIILMTGFLSIFNSTLLLKKWKLRYFILTANKLYFFKNNNLEALSVGSFHINSETEVNIVKSGFKKKFVLEVKNYQKERSIFLLCEDSEELGNINSKFISIHSSFLANWVRALKSAITRDKFSHTALPPPPPSSSDSYLSSFDLYSNNQSSNRLQLQPSGFDETKFAGENTVYEASGESPKLVSTRYVGSRPLTVNTKTFSPPQRPQKNPKRNPDRLQSMPLPQIASFPVSPNNNQGTRYFSSSPTRMSNNSLDHFSVSKMKVDSIHSSNSAFPFESQLAALNKLEAKEQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8L0</accession>
    <name>A0AAD5U8L0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_000003</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8L0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="661"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="695"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="768"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="817"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="860"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="886"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="11">
        <location>
            <begin position="617"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="12">
        <location>
            <begin position="659"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="634"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3228448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1062" mass="116842" checksum="323E31515A5D0BB7" modified="2024-05-29" version="1">MVTHGDWFDGGFWSSAYRGITAVDQYLKLNITGLYPNQLSQQAIADIIYDSAFGNNSYNHIGVTVSSDTVANAVRNVSSHVPVIAYNAGIELAASSSVLGIETFVGQPEYEAGLKAGKIFLEKGCKSVLGLMHEPNQLNSKSRFKGFRTGFVMENSSNVFSELFVDLKQMSSVEAKIKNALDTLTPSVDCIIFQNTALTASVYSELQSRNKTGVIYFAGWDLSPLTVEMLEKGYQLFAIDQQEFVQVYIPPLLFLSKYYSYTKVTSPILFSGPAFVTPETIQLKKCQIDATLPNCDSFFTNRTLNVIFLTHGALGNDPFWTDAYNGANFAAKIFNLTLSTLSETDRKGYDLKKVDAVLESLIDEPGQKDAIVLSLPNTAEFSKSLAKAKAKNITIISYGAGYLQSQNFGSSIHVGANEREVGEKAGKNFILLGAKNTVVINHEYGNKDLEERINAFTLAVIEGGGKIKENKEGKLNFFEMSSSVLDYTAIQIQKLLEEDSSIDSIIYFNPSIAKAITMALKNVPRKNFIVGGVGLSKFVLEAIKSGSIAFTFDEQGFLQSYLALSLIRLQKQYGYELQNDLISTGPTLINLSNVEKFISDCRGDTSIINGEECLACPVDGCGSGVCMDDGSCVCNHGWSGETCSILLETDPIYVKYSTGPIVLMSIAAFGNLLCFVFIVFFYVKREAPPIKSSSPIFIVLMLIGSMLIFSTIFLEVGIPTVETCTLEMWFFAIGIGLLLGNLLAKTYRIHKIFNRTLSTTAVRGIKNTFVLAFSGCILIIEVIITGILTILDPPHKFLLDNGKGNRIFICLPRSGSALPAIIVLIIFNGSLMLFATYLAIRVRGVATAYNESKHILISVYNLNFAVIILLVLVFTSSSVIGVEPKFFLNSIVILITNLSIILNLFVPKIISVYQKTDQTKTQFSSSKSNEPNNLSGIVSSTVKGSSYNKSAADFTNIQAVWTKGSVVSNITAEWEIMNFSFIVLKERNFLWVQSQNSNSIAKSFMLDLNLTTGIRKKDGTPVLIIREKKSNSELKIRFNSQQEYDIFVDLLPPEVYHKSTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8Y7</accession>
    <name>A0AAD5U8Y7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Myosin type-2 heavy chain 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MYO2_1</name>
        <name evidence="13" type="ORF">HK099_000436</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01380">
        <property type="entry name" value="MYSc_Myo5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036103">
        <property type="entry name" value="MYSc_Myo5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 8" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="12">
        <location>
            <begin position="78"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Dilute" evidence="11">
        <location>
            <begin position="1278"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="8">
        <location>
            <begin position="662"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1090"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1023"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1090"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1127"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1139"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="171"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3227763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1542" mass="178431" checksum="2F2C2B62D7B1F8E1" modified="2024-05-29" version="1">MEQLNSYHIGIKAWFPDSTEGWIMGHLISKNVTDLDYSFLFTIPERDNTQIVVKSTIENLISDKFTLPPLVNPPFLLVNNDDLANLSYLHEPSVLHSIKDRYEKEFIYTYSGIVLIAMNPFTKLDIYNPATMRIYSGKARDESDPHLFAIAEQAYRAMIRDGKNQSIVVSGESGAGKTISATFIMRYFAVVDDLHRDASITVNKASAVEDAVLSTNPILESFGNSKTTRNDNSSRFGKYIELMFSKPNSDTQSTKIVGAKLRTYLLERSRLVFQPESERNYHIFYQLCSALPLAERKEWGLETWDKYEYLKQGKTGVSPGMDDVIEYANTQKALSTVGISLTSQLDIFKVCVALLHMGNIKITGEKDESNIDENDPGLTMSSKLLGLNKFEFKKWMTNKNLVINRESTDKKIGLQSALVARDSVAKFIYSMLFDHLVNVINSNLCKDEENVGSFIGVLDIYGFEHFQKNSFEQFCINYANEKLQQEFNRHVFRLEQEEYVAEKIKWSFIDFSDNQACIDMIERKVGIIDLLNEESNLATGTDEQFAQKLYNKFSDTNIHKFFLKPRFGTSQFTIKHYACEVTYDVERFIEKNKDTVSDKQMEVLVQSDFDFLREIIKIPEEIPGNASTNTSTITKAVGTLGRNATGSRGKKPTLGTIFKNSLIELMKTMRLTECHYIRCIKPNQAKKRFLFEPQMVLQQLRACGVLETIKISCAGYPTKMPYDYFANRYYMLTKSNEWDLNDSKNWSSIIVKKNILSEDKYQIGLTKIFFRAGQLAYLEKLRTEKLRCIFDLFQKNVKRYRERKKYLEIKSSVLTIQRVFRGWVARKFVQTLRRNVAATKIQKVVRGYLARKDYKKKRDAVIKIQSGIKMFLAVRRYKNRVREIAAKKIQLCFRRKILRLWLKSRIKKIVTIQNLWRKKKARRELIELRKAARDVGKVKEKYFALENKLIELSQAVKTRDEEKLILLEKIEKLEKLAEKWKGIAKNLESRSKSVNEYLDEAKSSTKATFKDVELERRASEKEKNSLNYSLKKKDEEIENLTAELKLVKDWNRNLKERVLNASNVNGSEEIMMLRKEVAYYKSQLSEQSSESLRLRSNSVLRSRSRNRTPTNMSPTPDKSFVEESKGTKLSTPPSSFTRKTTKVKRKGSKLSHDTKFKTAPLQNGTASYEQLNSEKLLHVLKSTELKLELSQNLILDLTLPNFESNLSMKEIFFPSHILGQVLEKLFQNKLYPTAQDLMEGLMHSVDFITQFIEEKEQLRYNRGLSESPTTQSSLYGSESLDCLRTIRNNFENLVNKIFNGWTSKLYKAFVILVEPCIIECESLPEYVSNGKSSFWSNWGGKTKRDFKELIDHFKELNRMMDGYYLDQYLKNDILTLLLTLIGSEGFNILLTKKNFFSFRRGYQILYNVTRLKEFLAAIELNSNLKQFVMLQEASKLLSLLDGIDEDGAEMVFDLCPNLNKTQVMKLLSNYAPEEFDNQERFFEFFKAVEYLDFNDDNDTALLLSCELSEFTLPDVEAVEQVYAFIPSWMDVPNIGLALGFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSG2</accession>
    <name>A0AAD5XSG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peroxiredoxin family. Prx6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001339">
        <property type="protein sequence ID" value="KAJ3204113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSG2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03016">
        <property type="entry name" value="PRX_1cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1020.10:FF:000001">
        <property type="entry name" value="1-Cys peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000011">
        <property type="entry name" value="Peroxiredoxin PRX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1020.10">
        <property type="entry name" value="Antioxidant, Horf6, Chain A, domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045020">
        <property type="entry name" value="PRX_1cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009668">
        <property type="entry name" value="PRK13189.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF121">
        <property type="entry name" value="ALKYL HYDROPEROXIDE REDUCTASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="40"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="7">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3204113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="256" mass="28712" checksum="B86B823E75149CAA" modified="2024-05-29" version="1">MGLFSACVNCSEEVEDKKSRTAPIPTLTPEAQLETTHKSLRLGDTVPNFSAETTNGNIDFHTYKEGKWAILFSHPEDFTPVCTTELGAVAKLSNEWEKRDTKVIGLSCNTLESHERWIADINETQNADVKFPIIADANRKVAQLFDMLDFQDETNVDKKGMPLTVRSVFIIAPNNIIRLIITYPASCGRNFDEVLRVLDSLQLGDKHKIATPVNWKNGDDVIIPPSIKNEEADKLFPGYKVIKPYLRTVNVGVLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSS3</accession>
    <name>A0AAD5XSS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Multidrug resistance-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ABCC1_1</name>
        <name evidence="15" type="ORF">HK099_000601</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001141">
        <property type="protein sequence ID" value="KAJ3206205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSS3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="379"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="151"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="464"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3206205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="695" mass="78025" checksum="866FD31F0C4C41A1" modified="2024-05-29" version="1" fragment="single">DEKVGRKIFKNVLSKDNLALLSNSTVVLVTNNISLIMEDTESQIIYMDKGEIVERGTYRELKELRGQAAIMFDISRDSMSNSNLDSTSSSESDETETILEEDVSEFKSATNEKKETEEKKKVQIEESRESGKVSRKILARYLKYWGKSGVILASVLLILHLGFLILPSLWLATISKNNQNSSFLMSFGLYAIFVLISGFMLALCFFILIGYLSIRPSTKISASTIKSVIFTKMSFFDKTPAAQIINRFSSDIKMVDSVIPTTLANVLISIMEFLQFLILTCIATQSLIFLVPLIGVIYYYLQKYFLKTSVPLSRLAQISKSDLYQNFNEGVSGSTVIRAFQAEEFYKKKFKKNLDYNNIFLILNNVSFFWMVFHSSLLASVFLIAIVTTIILIPTTDSAFAALAFVSVSGITDGIRDILNHSSEFENTIVSVERLLEYTDLKAEEKLKVDDTKLLSNWPMMGKIEFKNYSAKYDTSDLVLKDFNFTVNAGERLGIVGRTGAGKSSITMGLFRIINPASGSIVIDDVDISTITLQTLRSRMTIIPQEPFLFPSSLRSNIDQYSSKTDVDIWQVLEKVGMKEYVTSNMPDGLDTVIEDNGSSLSIGQRQLICLARAILKDDKILVFDEATASIDVITERSIQHVLNSELKNCTVLTIAHRLNTVMNSDRILVLDQGRVVQLDKPENLKKDLDGYFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSW2</accession>
    <name>A0AAD5XSW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000167</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001022">
        <property type="protein sequence ID" value="KAJ3207932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSW2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="457"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3207932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="571" mass="64646" checksum="FA666863F041BDF0" modified="2024-05-29" version="1">MDHCFVLDKANYCGPAFENVLISKNDAFFDQASFEHYLTLEINNYGSSIIQFNCSDSQKTLELWEKRAFQASFECSKYAYQSFYICSTQAFSNTTIPSSFETVVPESLKLCNSQCQLSKYSFIDNFLSNDEVCPVLSEINSDRNSLIMQFEEFCNIFTGVNNGCYPGSPSESSNCGFISPSAALIGCRSHINSQDPCCISLVSKFPVTSAENSKFKPSTTSFISKTKMFNPPTTETLEVSINSIENTLVETLIEADQEGGTLEKVNRASAKEELPHNNMLPGVIATFVILAMTIVVTCFIFRKKNLKKKKTLSLNMDRLKSELTEKRLNYRENFPSPSLKVEYIKAIKNVSKIPLKTYSMNGDIDLTEKINFKKIKSDEDSFFKNTEDHCILNSKNTRIQILKHNVSKNNTSEQKALFSETQTPNKYERINVSMRTSSSSIGNLLLSPKTKNFILDSKAKKMIVLVEYKSSQSDEVDLRFGEEIYVVEKFEDGWGLGIKVTDGLSGAFPLCCVCDSYKFKKEQELLIHETLRQNSSSNISGRTEIEWVENIPIKKGLKRVTESQLYDEYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSZ5</accession>
    <name>A0AAD5XSZ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001013">
        <property type="protein sequence ID" value="KAJ3208091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSZ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.780">
        <property type="entry name" value="Vps16, C-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016534">
        <property type="entry name" value="VPS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006925">
        <property type="entry name" value="Vps16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038132">
        <property type="entry name" value="Vps16_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006926">
        <property type="entry name" value="Vps16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04840">
        <property type="entry name" value="Vps16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04841">
        <property type="entry name" value="Vps16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007949">
        <property type="entry name" value="VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps16 N-terminal" evidence="3">
        <location>
            <begin position="4"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 C-terminal" evidence="2">
        <location>
            <begin position="499"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3208091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="76753" checksum="88670A0059880692" modified="2024-05-29" version="1" fragment="single">MNATTNWTLLKEQYYVKNVVYELNWNIKDISKFIVTVSKCGGAIATIRNDKVMFQLNSQPTVPILNIYSASGKTLTQIKWDKGRIVGFGWVKSEKLCCVLEYGSVRLYNLHGEYTQFSLGQIAKDFGVLDCRVWEDGLVVLTGNFKFIFVSNINETRPKLMSDPGLTEIPHSWEIIKPEFSSSGHLEILVSVNSTVLTVDPISYLDQLLNDGPYTKISVSASGKFIALFTVHGKLLVKSKDFQKTLAEFKTNSSSVPMQLEWCGTDSVILHWENFLLMVGPGGDWVKYQYDGYVFLSPEDDGIRIFGPKKSEFLQKVPEPNEKIFKFGSTDPGAILFDAYDHFEKKSPKADENIRSIKTELTEAVDTCIAAAGNEIDIQLQKTLLKVSSFGKCFLDYYNSERFVTVCQYIRILNAVRDDEVGIHLTYSQFLSLTPELLVKRLVNRNLHLLALRISEYLKLNTNKVLIHWACAKIKNSANNEESISKLILDTLGRSKSGISYAEVANAAYKQGHHRLATKLLNFEPQAANQVPLLLTMEEDKIALQKATESGNTDLVYLVLLHVKRKLPIADLFLILNGNPLATNLLISYCKQMDPLLLKNFYYQEDKKGESAKIIVKDNASILDVNEKITQLKMAYKLFNDDRDYIFEAKATDEQIRLLQSQIQLERDTGHTFSNLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSZ9</accession>
    <name>A0AAD5XSZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Copine-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CPNE8</name>
        <name evidence="6" type="ORF">HK099_000106</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001007">
        <property type="protein sequence ID" value="KAJ3208205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04048">
        <property type="entry name" value="C2A_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04047">
        <property type="entry name" value="C2B_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037768">
        <property type="entry name" value="C2B_Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="94"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="270"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="558"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="561"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3208205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="596" mass="67465" checksum="43B8817C49829F4E" modified="2024-05-29" version="1" fragment="single">MIVLYTKSLLISDDWVEIGRTEVVKDNLNPHFQKPFVVEYVFEEEQKLKFIVADVNGDVKPSEKESLGFIETTLAKIVCTRGQIFKKNLIHPYRQQQGSIKIVSEEVIDEQTKLTFHFEAKNLEKKDFFGKSDPFYQISRIQEDQSYTLVHRSEPIMKTLSPIWPQLDINLGVVCGSDVNRKLLVEVYDWNKSGAHELIGSFETTFKKLTAKIGGEFELSNEKNEKSKKILKAGQSEELPKICGIFIVKKFQSLKMPSFLDYVNDGMQLNFTVAIDFTSSNGDPLKEDSLHYCNPYKANDYQQAIMSIGSILEDYDSDKTFPVYGFGAQIQGELSHCFPLTRAEGESTEGMEGLLKAYNYFMRDVNLSEPTHYAPLINSIATKASNDLQKTGVGIFYSVLLIITDGEVNDMEQTIKEIINASTLPFAIIIIGVGKADFSKMIFLDSDNKTLATKDGKKRAARDIVQFVPFRDYIGVRSHKLAKAVLAEIPDQIIEYMTTHGVFPKGKKPKESESVMSLIDQCEETKELTLLDMLEEEKDKDDIEDRVSSVLNNFSFSNTESEDKKINSNDDTSDENRKSTSKVPRLSTGTRSFKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTB3</accession>
    <name>A0AAD5XTB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_008128</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000860">
        <property type="protein sequence ID" value="KAJ3211016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTB3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="14"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="536"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="547"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3211016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="673" mass="76947" checksum="43948D0CD029B17E" modified="2024-05-29" version="1">MVEKVWGESKLEDFRLMSKLGEGTFSVVLKVKHKKTGSAFAMKRFRKTFQSFEDVEGLREIQALRRLNPHPHIISLEDIIFEPKHGILSLNFELMDCNLYELISKKSPSVTEEKAKLYMWHICKALEYIHGNGIFHRDIKPENILVRDGHLKIADFGSCRGIHSKQPFTEYIATRWYRSPECLLCDGMYNYKMDMWSAGCVLFEIVSRDPLFPGTDELDQLHKIHGVLGTPSQKVLRHMLGNRVSSVKYNFPTKEGTGLKCLVPTASPECLELMEFLLAYNPDERYSSKEALRHNYFAEMQYKENGKIPEETVHPVKKKKSQLLLESMPTTIQNSLTQAANAYLKPALQHEVTGKSNINLESVANVSVSNKENQIIKEDHSEIAQNSLSEKQALNAKKEQLLETTIKKDTMPSTWEITKTEDYTNNINKDSKLADQNEPKKQISQISLKNNNAPKTEATTLQKKMQSFHQVSDGKDNTPQLPSVNLMYQNSVINQHQVQHQTQEKIENLKLPDLTNSNNYYDVKDINENVKKVNRDLQEGGQQHPIVQRRTRRRHDSPKGPRYPGGKRRLIGNDTSSTRNQGNLGIIGKHAQVTVPKLPSLSNQYQINHNPQKISKMNNSNVNNTLPSLNVEQQKYKTEVATKENLPNLPVIFQNETMNGLKNINTLPSIKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTI8</accession>
    <name>A0AAD5XTI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisome assembly protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PEX12</name>
        <name evidence="18" type="ORF">HK099_007762</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000785">
        <property type="protein sequence ID" value="KAJ3212321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16451">
        <property type="entry name" value="mRING_PEX12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038074">
        <property type="entry name" value="Peroxisome_assembly_p12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="247"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3212321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="289" mass="34159" checksum="C0E1EBB5C5EFD85E" modified="2024-05-29" version="1" fragment="single">MEFLNDFSQNESPSFFELTLSSQLNDLIPQAMQYSLANLTQRYPSLLLKILNKSDEIFDASFSENFYGLKRINNAGTYRLQNFERYASLIELVFFPYLNSKVEQISEQDQHLIINTTSNAQKKRFIKLKLQLKKSLMLYDTKNFEVAANNLKKMQQSRLNKEFFFKHPIKFIKNLTDYVIFENFDHLKTILPLTIFIYKFFDWWYKSEFHNKGNNFVIPPPPKPTKEMELSYVENDGLEIPTDSNICPICLDARVNPTVIETGYVFCYSCIYEYIEKYEKCPITLKRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV57</accession>
    <name>A0AAD5XV57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD repeat-containing protein 87</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">WDR87</name>
        <name evidence="4" type="ORF">HK099_005096</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000384">
        <property type="protein sequence ID" value="KAJ3218354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45532">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45532:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="293"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="563"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="708"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1039"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1170"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1280"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1053"/>
            <end position="1073"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1893" mass="216785" checksum="147547AF34DC2AEF" modified="2024-05-29" version="1">MLTDLCSKIACPERSKIDLYEEDLKYNEDGEIESQITEKTLIPDYTPNLPILPWNDTRSLVKNLTNSKNISDCLAGKGNLIIPITIPYGFQLQKTLAHPNSTLRSVIYIQQSTSAELFVSLDRHNVHVWRGLTRIKKIGTLGQGSSYRDENIKVTDEAIKKGVHGINKWKYIEKYRIYVVASNQLQLRILDSHFAEIFTTSSVKPVLSLVYVSKSEEIITGEVGYIRIWKLEYKSVRTQDEYKLLQRMLVELEEDEWAGFVSYDAIQNRIIAAVDNSVHMYCFLTGKKLGTLKEIHDMSITFIVYYDPLEYLITAAKDGEVKVWNSQNCLVWSFQEHFSQISGLELLEKGCQAAPKSMPLILTGSVNGKIRLLNFESGKCVYRLDTQHECLGLQFIKNDTFFHFSKKSIFVWKLNRYHSTFSFLRSQPMILKRISYANNSARILTTTSDGSIKLISPVTGNCLITGFPVHKDVSLIDVAYDIQNEKIYALNSSGDIAIYDCKANPCKVLNIWEFSQKDEKLNCITGVNLKNYNNSSNFFLMCGSKNGQFLSINLNDGKQEVLVQAHIAEVTMLIFDEKSSCLASVGKDMTIKFWKLRYMDVSPTSSLGTNITADNTANLGKQKQLNSLKSSLTSENKNLSKQKTNTTLNMMFELDVVINISHLNTIPKVVALNPFEKIVSIPFQNNIIMCSYEKNCTLEVPHKEKDKEKSSTGNITSISYLQSFDIWATSGTDGTIKIWKRENDGEALVIREIQFNEPIQAVCFCNKPGDLLVGLQDQISLVRLQDYFPVKLLRQSEKLKFIDDIIETPLMFDTQLDFWEFVYDNDLKKHGKIDFWHLQKKLKVEHKNDNSLNNEQVEYTLQNKQDLVKKRKNRRIFLETEHDLYKKQLNRLKGIVKDSPTRKEVLENNFLEETYDKSSNDMYLSLKASSNINLLPTGYLNLKSPTSTTYGSDSDDENRFVKEKKKTVVKSHFTGVKNEVTHHHYHTPKLHKFNGIPAFLLKPKAKVMEEVDKKTQEEKKKQLRRQLRMMGALPNSSVANQTIAPQRPKSNKKTNFTNRVQGSEGFSNNTVGNGKSGLGKDPKLSMNVIEALQKLRLKNAAFKAKDKNSKSDSMGSVYSVIEDEQDCFDESARPSSVEKTLAEKEFELPPINKGELETEIIEVLVGTNTGENENENKSNTEKVIAAEVKREEEDESERNSTSSIDEESEDLETLMSSTGPKRKTTILEFVPVNPKVISVCLNLNNKVKDFPSNSHTMTKFIAAADVHSSAFGGCQNDTRRKSVNLNFKKMNEKIRNQKRNQKNGLSEKKVYNNEMEEENSLLQNEEVNRVEFFLEPMVEINYETASKYIWDLIRCEKTASLYEAIFKLAYHHSNCNSENFEVTLKSLIKVLKSVIINGGEQEKCEAIKANLYLHRVFQRDIADPYNTLLEHQLVLMNDSSWKVRAQITSCILGYGVYSPEVIVAVICRLADQNRIVRKIALQNLTYFGVTTKLSLKNTMIMVGLLTANDDSKYSSTYLDRLLAQLKEARKWEIKSQLQQVKYWLGGLNMKTDAELLREAGYSDHLAELYSTLNEKEFHGEKSNIVDIVGGVFSEKKGFNSSTSNSHGKNYSLFLKKNQLLKNSKYMEFVDQLKNSPYRNGNSVKKKNSYKKGENVKSEIKRQVVQVNLTKELKKLRPFTAGSISAAGKNRPQSAIVADLIIPRARIIRTRGRRHHAKLNVMSFKDKSSLRYTSQIKEEPQVDSWMEDRLIIKDLLKQLQLKDEQLKKLKFNEKSPPPLTQSLNKNVLKMVDNLAEKIPFIETKFKTIDVFIHLEKFDRYITTATNYDCYHDELCLMASYDKLADVHQVQCQLHFDVTSDWSMIQVPAYRSWLVSVMNRSFEKILAFFRRIQIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVJ0</accession>
    <name>A0AAD5XVJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Katanin p60 ATPase-containing subunit A-like 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KATNAL2</name>
        <name evidence="10" type="ORF">HK099_002485</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle pole</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001821">
        <property type="protein sequence ID" value="KAJ3200872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVJ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19509">
        <property type="entry name" value="RecA-like_VPS4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000434">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03025">
        <property type="entry name" value="Katanin_p60_AL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027497">
        <property type="entry name" value="Katanin_p60_AL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF78">
        <property type="entry name" value="KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="230"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="49"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3200872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="484" mass="54973" checksum="555E418BA5855E20" modified="2024-05-29" version="1" fragment="single">SLESESNVSLKKYCVADNLDLTTILQEYENYYAIKFNRQPKITRHLTKAEQPKFNSSSNKPKLRPIQSEPNLNFFNNDEKKPIMTTTSPSPSIKKSEKINNNSLANTKKEQLNEPKLDPENGVIIHGNSVNNNSNKKKLSSNAELKIQDNQVQVVEDDLYENKMLKPIPNWGGNLELKELATVITREIFSKNPNVSFDDISGLEKSKKLLKEAIVFPIKYPELFTGILTPWKGLLLFGPPGTGKTMLAKAVATECKTTFFNISASTIVSKWRGDSEKLVRVLFDLARYHAPSTIFLDELESIMGSRGEGTEHEGSKRMKTELLIQMDGLSKTNDHVFLLAASNLPWELDSAMLRRLEKRILIDLPDFESRKNLFKIFLPTDMKDGYGNKMVMENLDYERLSILTKGYSGSDIKIVCKEAAMRPLRKIFKLLDLKDDPVEEDETVFQRDLISQSDLEKAIKTTKPSCDLSLTEKYTKWQEGFGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW03</accession>
    <name>A0AAD5XW03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">PDZ domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PDZD8</name>
        <name evidence="12" type="ORF">HK099_003826</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000257">
        <property type="protein sequence ID" value="KAJ3221020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF0">
        <property type="entry name" value="SMP-LTD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="157"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="614"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="845"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="951"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1048"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="847"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="968"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1063"/>
            <end position="1073"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1347" mass="151067" checksum="1CAD9C797F1A9146" modified="2024-05-29" version="1">MAVGHRNVSLICTQMAKICSHNFVSYPISSFNVICNDPPILNVSYEFSTFTVAFYGIILTLVVEIIILYIFLAKLFNFDQSKAKVKIPDRDGFQGTLKVESEPKVPHTHTQPYPTSVTEFLKANLSDKFRDTSANVTPISNTSWGIGDPNCTFTTSDTEKCNYLNIVLNRYFIELRASEYFKWKTKTKLNEKFSAKLEGSSFVTSCFIKDIVLGDTAPCIEGVRILHGITEDIAVVFEADISYGGGCYIIIEVTLTGGLVLPVKIALEKLAGKMRGRVPSPSFTDMISIAFAEDPGAQFTVDSPITLQKNEKLREFVNKLLGKLVRRLFLDLWVLPNWRNFFLPCMEPNTEEVESRELAKVVTTSSPPRRPTTTTTITDRATSFLRWGGKSQETLPTASPIENLPTILPEFQIAGTMTSFNVNTTLINKSDILQLANELESKLLPNFLRLAKEGFIENMVLDPNSAWKLLKSRNDISVFRKKVNTIFGVIEVFRSIIKIYCEADKVYSVLSNPAHFQHIDDGYLGSSVLKEIDSSRSVRQSTYQFNKNVLREYKVFEVKRKLAEEELENIEHGSNNISECSSSADPVNEAKVNGEEGIERAINNYIVVSRSIGNLIDGDSESPTNTKEKEEKKLTHKSSSELNVEHDSTNSSMEHSFSADEIYTLDTKNLSEEFPKHLNEINPEQQHLEAPERLQSITIKPRNFTEPISGSEVSNAIKSIPEKLNNKVFINGYLIESNGTEKSCTVTILSQLSSDLNRLEINFTNSKKIKDFIEELETLTSSISSDQLDLQNIADQQNTLRRRKTTNGAETDSNVPPRIEKIKSYISNTANNWIKNRKRIASHPEDFSSSFNATANSPISDESKKIESATPSEYKSQELPLYSSEVEQLEQQSVLPPITPQTLSLTGIEEKSALMPASAQGNFIDDSDTGNSPPEPQSTIQERVSFESAVSNTADSNLEIPPRESSLVEESTQKPTVVTSAEYQPLDLMSDKPYIESNIVSKEFAKYEIAYDCKSGPVNLEWNFFAHNKQPIMFGLYYKQKAPAIERKEDNDGTSAENDEFLSEDKKNSSDYTRKELGGTNLLKLFVENTADKSERVLVPLSLINGSAHPSLGLMSLDSFPSGTFVFIWHNNQILRKTVSYKVDLMLKSEDEYRTNLSFDISVPRKLSFKLPVLYDFKGDTHGKSPFLCYEFTTGGYELMFGISFWEFEYDDDGPESIKLVSGSEDSNLEDEKGNCLDNNPVDQRKSLLSSRLANVVNQNLGNSIDFSGISSSEDNNEICKKEVLSLKKYNSQRGLIQGKINIGKTAEGEGDANNSDRFGVYNLCFDNSLSPVLNKHCTIKVWIIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW82</accession>
    <name>A0AAD5XW82_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglycerate mutase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001255">
        <property type="protein sequence ID" value="KAJ3204889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW82"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07040">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="30668" checksum="21BC7654A1BA36E0" modified="2024-05-29" version="1">MENAVNDVLLEVYLFRHAERIDFADENWILCKENEPFLYNPPITKSGIEKTKLLASKIKLNGQPIVYTSPFDRCIQTALAFINGNPCKCTKSNHHCSVNSKNQILPLPTPQKNLKIEYGFSEFFTPTYFKKKPDIPTLSEIKKKHFSQQNNNSTCSKQYLDLTYDTFMDIPRIFPESYNGMISRINQTFFNLVQSILSIRNNNLENVENNFSVQKVPILLFLHADGINSILNYFVKEDDYQIPYLFCCKLTLKKGKSKFYMEIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWD9</accession>
    <name>A0AAD5XWD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000219">
        <property type="protein sequence ID" value="KAJ3221620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWD9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42858:SF1">
        <property type="entry name" value="LD15494P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="1">
        <location>
            <begin position="57"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="459" mass="51994" checksum="C73875F425BF6B10" modified="2024-05-29" version="1">MENLINGKYTYGDKTLFPTNDPDFISFEYGTPENKLLPSDIITVATKHKFESPFAFTTLQYGPSLGDLEFREVLSTFLTEEYNDGVPVLPQHLSISNGASQSLFNIISLFTDRETKFLIEDPTYFLAIKIFEDLGVNIEKDLHSVLTDEGGIVIENLDSKLKELTKLNPNLLNLKKFSKTDSKKKKFKFFLYLVPTFSNPTGSTLNLQRRLQLLKLAKQFDLLIFCDDVYNFLSFDENFKIPKRLIALELENFNAEVEFGNVISNCSFSKIFAPGFRLGWVEASSFKSSFRIITKILNAFSGILYSGGCPNHFATGLMTSIIQLGFLKTYIENLKSCDVCCDALLKYLPAGCSFVKPKGGFFIWLSLPNFVDTTQLFLDLKNASLNNIEIFNFKLKCEIEGNIDKLVKFEKVSFAPANTFSVSKKFGNCLRLSFAFYSEDQLLLGIVRLCNLLKCIIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWS4</accession>
    <name>A0AAD5XWS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002464</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000181">
        <property type="protein sequence ID" value="KAJ3222314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045182">
        <property type="entry name" value="JINGUBANG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22844">
        <property type="entry name" value="F-BOX AND WD40 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22844:SF387">
        <property type="entry name" value="F3I6.5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042003099" evidence="4">
        <location>
            <begin position="18"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="404"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="444"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="484"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="524"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="594" mass="64999" checksum="4BC879CB50B32F97" modified="2024-05-29" version="1">MKFWSPFVLIILQQVLASDSSASKVATLQSSSATVCTSPVSSCLQKCLKNLNIFQNGNATSLVPAEVADCSCETYDGKYNSVGAYGKFGDNDGVWGIKKSSGVLSLSFKNGNICKTAYGVQVADAETNRRLQEENSLQKRDVTCTDKCPPSYMLNNEATQCCSCCDWYDFYCSKKYYLDCKYIGQNEWGPWTSGSCYAAYTPTNGVRDVYRSCSTTSAHFKDCDKGSSSYKTQSCSYSLPTETSYVTTTRFSTVTSTSTTTSTSYATSYATSYATSYSTSYSTKTLTTTITQPTTVTQPTTTTVTQSITSTITINQCSANFNKNFTESGPAVNAILTDNGYLYSAHTGVIKRWDLKTGEVVNTYSTPNIIVNVLQIEKSSLFAACSDNTIKSWNISTSSTIGLFTGHTDSVVSLVVKDGVMYSGSKDKKIKEWDIATGKNTRTFAKHTGAVYSLLVSNGYLYSGSSDKTLRQWSIALGTNTKSFVNHQNVINTLLINNGLLYSGSYDKTIREWDLETTKNTRTFVGHTSFILTLAVNKNSLYSGSEDQTVKEWNLNTGVNVKDFNLASAVNAISIYNNVLYSGYSNGAIKQWQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX29</accession>
    <name>A0AAD5XX29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000866">
        <property type="protein sequence ID" value="KAJ3210912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX29"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3210912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="75" mass="8728" checksum="5AB2A2E553BA86AF" modified="2024-05-29" version="1">MNLPKNKVIGFDIKSATSNHGPFNLCSKEYLNHVKDVYIKETMTIPEVFFILDDPEMFDENFWGKEMTTYENFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX74</accession>
    <name>A0AAD5XX74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Choline kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000142">
        <property type="protein sequence ID" value="KAJ3223146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX74"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004103">
        <property type="term" value="F:choline kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF93">
        <property type="entry name" value="RE24176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="52403" checksum="D430F5EB68F8AACB" modified="2024-05-29" version="1">MNSETTFFLPLLTESSPQSSNASLETYRDSLSPTASKVLHFEHPFDGSIVDSHETLTRSWIFTYLAHYNIPTSDHTISLKELGNHGFLLKSKILEVLQKLLPRQWRNITDPNVITLTRITGAMTNMIYKLEANINFKKFSCLLRVYGIGVEQFVERDRELLCACRLSEQGCAPKLLGVFNNGRFEEFIDSITLVKENLREPKISEIIAKELAKLHKSIFAMEKEEKNVELWDKLWDLFDLASVSNLELKSKGGNLSKTTGFDLSKIKEEILHLKKFSAKIDSPVVFAHNDLQYGNILQLNSDKNKLMLVDFEYAAANYRGYDFGNHFCEWAADYHSANPHLLDYTKYPSKNEQFLFFQSYLKEFNCEKMNYQVTVEELNEIYKETEFYSLLSHIFWGLWGEVFATLVKFKVSFYFYIGVIQASKSSIDFNYSSYAEQRFTQYFLTKKRLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX77</accession>
    <name>A0AAD5XX77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CFA20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000140">
        <property type="protein sequence ID" value="KAJ3223186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX77"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040441">
        <property type="entry name" value="CFA20/CFAP20DC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007714">
        <property type="entry name" value="CFA20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12458">
        <property type="entry name" value="ORF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05018">
        <property type="entry name" value="CFA20_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFA20" evidence="2">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="861"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="915"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="638"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="801"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="874"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="887"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="932"/>
            <end position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="969" mass="110390" checksum="6BA211C1433AB8C5" modified="2024-05-29" version="1">MFRNSYQGGISNEIFSAQGSASTIMNWKLSAHNSIKRLYEKDAKGYCYNSSKTGKFTFPKDEKQSAYLINQFLILQVFIPLGEHVLIELSITDLNNNKRRFIVSSWNKETKLTALHVMLPMNLIKRSVWLNLCFDLVSFVTEFFRGQTFRSLDNIQLSGAFKLRKIFMMKDKPADTTGEWDFSNSITTTEQIPKNLNFNFGVEYLTQVMTAERFLTENPLNRPSNELEISRIQSGCVSHKIAFGRRTDINLPPIDKSATRISTTSSSKRYTPHEMLVVNTTPKKEMKKVLKKSSSKLEILKNINTEITKTDNDCKTQLDYNPQIYQEEVDENTQLQDTFEVHKISRSRKPSSNSLNLNRSRKTSTTSPEIIKTPLLNHSRQHSFDSNSTAEIRAKTPLLADYNAQDYDSYDALNDEITNILNKGCSMEEIALPSAAEDYTENLMQSKEVHASDKVLGDLEVSMSSPHQYQPVDEENNNIASNFTENNNEPSEFINMENGTGCSQQTEGFDYISNSLFSTKSCVVNIQKNLLNQGIDQRPQTGLLTEGSASVKKAKDFSSNMGCDSDTKILKEFKEDILEQSYVNNDSGIIALERCENVGFQMINTRSRLHNEDTKEGDKASPTVSNVEAENFDISRPSSSRSQKNRLSSVEKSEKFVLMENCMKKDDNELLSALVDEKREVINSIPPIAKLERVRPKSSHVRKQSKHKEVRTYAASTPSSPFIRRSRTENFLVRNIVKENDAKGCSVMSNKISATCSKVEKELNLADGEEISTEKELTNIPHPPQTLNSIAKTRPPSRLPRRSESSLKQSKESDKNSLPLKMSQEYLKEASVVEDKRNEMILEAILKDSLNELKLISDNLEKERKSSESETDLSEYSNNKQLTNQKFPEKKDKIMDSPKNEGFLRNATIENIKENSMIEHDNSGEKMIEDGKDVDEEDEEDEDDVELVFDEKLQLFQDIKTLKYYTKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX86</accession>
    <name>A0AAD5XX86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase S59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001071</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin GLFG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000128">
        <property type="protein sequence ID" value="KAJ3223488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX86"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034398">
        <property type="term" value="P:telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2360:FF:000001">
        <property type="entry name" value="Nuclear pore complex protein Nup98-Nup96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.10">
        <property type="entry name" value="Peptidase S59, nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007230">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036903">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04096">
        <property type="entry name" value="Nucleoporin2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21240">
        <property type="entry name" value="Nup98_GLEBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82215">
        <property type="entry name" value="C-terminal autoproteolytic domain of nucleoporin nup98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51434">
        <property type="entry name" value="NUP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase S59" evidence="10">
        <location>
            <begin position="727"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="79"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="534"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="572"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="79"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="549"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="576"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="877" mass="90865" checksum="E3AE072CF5086404" modified="2024-05-29" version="1">MFGSFGQQQQQPQQSMFGQSNNAFGQPPASGGGLFGQPSNNAFGQPQQQSSLFGGGSSASSNAFGNTSKPAFGFNNTSSGFGFGSQPQQSTGSSLFSSQPSSGFGASSNATTPTNNQGTGNPAYSPLQEKEGSTISTTCYYQTISCMPAYKNFSLEELRFQDYSLGKKFSSGTSGAPAAFGMNSGFGGTSTPASTTSFGAFGQPATTTAGTSLFGQTQPSFGSGFGQNTTAPTTGFGFGSSNTTSAFGQPASSTGGMFGQSSAPSAFGTSNTSGLGAFGSTNNTTTSAFGAPASTPSPFAFGTAATNNAPSAFGAASSTTPAFGFGAPATQQPATGTGFGFGATSQPATGGGLFGNSTTPATGGLFGNTNTSNTGGLFGAKPAGSGLFGAGSTTSTSLFGNPPATTTASNLFAAPAPLNFGATQPATSTTGLFGNTSQPSSGFGATSTNLFKPTGTFSGFGGGTATNTFAPTTSTSNFGGFSGNSFSSTTPNLFGQSTQQQQAQSVNLTASINRNPYGNIPLFNEPKRNFGSSVFATPAGSSSEDKLKNSSIHPSFSNKLTPKSISKMKLRGFDLSSPSKNSSTPTSLFDGSNRDDQVLGLDPRFQPRVSVKKLIIEEPEPTRKEIVSEASNVFDADLEERASNVYEEYKRNANSSTYYEEESITINSTPIKANTNIGKSLPGMQSTIAKQRIVKEPSSSNFSQPKNASPVSPEKTIVLPKRAANLPENYVISPSLADILKKSEDELTEVPNFVVELPGVGKIEFLEPVDIINSTPSKEKSEIKKIFGNLIYFEGFAAVVYDEKYAIKIPPRGSGFNVKSRVTLYGLWPKDSQGNIITNPNDPKHKNQISKMKKVADTKFVSFNNTDGSWCFEVEHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXN8</accession>
    <name>A0AAD5XXN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005323</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000409">
        <property type="protein sequence ID" value="KAJ3217793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXN8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035329">
        <property type="term" value="P:hippo signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00083">
        <property type="entry name" value="bHLH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051583">
        <property type="entry name" value="YAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17616:SF8">
        <property type="entry name" value="TRANSCRIPTIONAL COACTIVATOR YORKIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17616">
        <property type="entry name" value="YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="92"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="7">
        <location>
            <begin position="301"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="98"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3217793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="339" mass="39005" checksum="8F1041529D1C6540" modified="2024-05-29" version="1">MDSSLQIFNQEPINEVKQYIDIPNSKYPPSYDTCSQSQQFTSNKDNGSISSNKTSDTTYSAYSFNSSFDDSSERDLDEEMTENLSNLDRDEYNRILKMEKSRSSREKIKESLNELKETIPNLEKKTRISTPQLIKETVKHILSLNSALKNSKEAQISQLAEIEELKKNLLEKKFLLFQSEQKISNFIQKKQQEFCMNNPNLPDMEKTLQLLILNQNLQLALYGTLQGINLNGIYNNANVVTGNSGIPANFSTTMPTFTSPMNSLFLNSMTSIPMPQQEQQSSLQFSTQQFPLHQKLESSQKQLPEGWEEFTDNFGRKFFVNHIDKTTTWLDPRRIVSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY53</accession>
    <name>A0AAD5XY53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Myeloid lymphoid or mixed-lineage leukemia 5 (Trithorax, )</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MLL5_2</name>
        <name evidence="6" type="ORF">HK099_006569</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000578">
        <property type="protein sequence ID" value="KAJ3214990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY53"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462:SF3">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20826">
        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="33"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3214990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="78" mass="8962" checksum="778C0A64EE332704" modified="2024-05-29" version="1">MASKRKANTKVPVLKKLDLGSESELDFAEDITRCICLKTHTTGLMIQCEGCEVWQHCECIGLKKKNIPKKYWCERCTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY82</accession>
    <name>A0AAD5XY82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000806">
        <property type="protein sequence ID" value="KAJ3211920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY82"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="812"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3211920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="860" mass="98955" checksum="97CE902179778074" modified="2024-05-29" version="1">MNTTFNLLQQLKEQKSLPIEFDLLNSKHQKTEMSELSELPEYSNLLNALSHMNDTELISTLENIRESVQHDMTENQKEIDNEESGNVCNGLEKQQFLLNKEQEEASAIKYLDMIRLKHSEGAKKLALLESYRETQLAEKLKMQQKIEALDEATKELKLMEELVGALKDLKEDHVEGKSNLILSVDQLQLLKSSSNEEGSNDFNNLTKSLDMLAGIQLKDKKIEELKAKIDNLENCKTALISKRDSFLDLIKDPVAQQPVQVLEQQTSQILELTKSEISNLEKKQTLLTILSGSDLNFNLSDDEGVNNNEEEIVDNLMKRLTAASTTTDHAETEKVLLTKENEVVIDGVTDNVKNSESSEVGNKEEVIYEEEELTTDESLVSTADKMKETLVKIRAGIEQIMANLSEMDKFVPESESEKENVELLRQGLHRQLNEMHDIEDQILNYIQVIEEVPSNIKEVMQSESEDNDAVGDEETIICKHGNRSVVGKEDLIPSEGPSVSKDQYKIKNVLQLDKFTNPLVEITGEEWKESAEINELEYENEDVDEDTNLKGLFDLNKDKVYKGAANMISHHEKDPYFLLQVFKEVSKLNTGYLKQKFLLLLDEINNVPPFVEGDEEYFSENITEQDDCYGKGKEFVDFVKNSAENSQICGGVILNQSRQRIKKNENKLQQHGVEDRYSKVPVVKKFLPEETTIDELTAIKLNLKKYVENLNTKRFTKAQVLELKEIFLNLLFKDAIKSTLSATNKNIKQQVLLKEKKKLLKLTEKQFDYLLEKYFNRSISKQKEKLFREMDTFASEVFFELKNFYNFEYEEEKLNEESDSETTDDEDDNDYDSSADEEVDEIKLTFERAKAWREFGLPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYG6</accession>
    <name>A0AAD5XYG6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cilia- and flagella-associated protein 69 ARM repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006344</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYG6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902093">
        <property type="term" value="P:positive regulation of flagellated sperm motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048732">
        <property type="entry name" value="CFA69"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048733">
        <property type="entry name" value="CFA69_ARM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14716">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14716:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21049">
        <property type="entry name" value="CFA69_ARM_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cilia- and flagella-associated protein 69 ARM repeats" evidence="2">
        <location>
            <begin position="80"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="401" mass="46413" checksum="8A9C2881CDF2F4E8" modified="2024-05-29" version="1">MSMISNLHQHPLQPKSGNAKGKKFRNLMPIFTAAINKNFNNKVNFNEFEENQLQSAKQKLLKSQEKIKSENNPSVNKKIDYEKIFKLFNGKQTTFLFERHCSILEKLSKVYENGFPVDELKEITDLLKLTKKKIKTGGKELMKPLLKLIRICGMNFIKSNPYAEYSDEELNDIVNLITESSSMIEFNNTEILSCVTDNLFDSSQPSEIYKLEKTQVTNILLDYLNNYVNDSTQLEMILRVFSKFTAHSEIICHQIIDSNGLEIICKAVNNSDDMGIVTLFVDCIWNVVDSQYGKTASKILCQHDNLKIFSKIFENFSLNSNRTLKKQLRNEIGILILEISQKILISDFKIFKSEVEYNDEVEENNLIMNFKDVGLYDLIFKFLKSVEINNLSLNHYHFTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYI3</accession>
    <name>A0AAD5XYI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">U3 small nucleolar ribonucleoprotein protein IMP3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">U3 small nucleolar ribonucleoprotein protein imp3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">HK099_006015</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIAS family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000498">
        <property type="protein sequence ID" value="KAJ3216101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYI3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16650">
        <property type="entry name" value="SP-RING_PIAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000006">
        <property type="entry name" value="U3 small nucleolar ribonucleoprotein IMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.780">
        <property type="entry name" value="PINIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023321">
        <property type="entry name" value="PINIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038654">
        <property type="entry name" value="PINIT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14324">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51466">
        <property type="entry name" value="PINIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="12 17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PINIT" evidence="21">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="SP-RING-type" evidence="20">
        <location>
            <begin position="137"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="237"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00069727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00072223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3216101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="671" mass="75869" checksum="0A6A26BA171EBAC9" modified="2024-05-29" version="1">MHSNKTNVNCFLYVGELKKNPITLVSIIPEKPIAVQFHPSFQIFVNSQHIPANKYLTVKKKRMIYQPLNITSYLHLRENANNRVEIRFNAESSKYVMKVALVKKISTSEQSERLKNSNFVSKEILVKALQQKALEHQDDDLIATSNIISLRDPITMSKIVTPARSKECNHDQCFDLETYLMYHDSAQEYNCPVCSKTLSWQNIFVDGLFLEILNSVDDEVDTVDLLPDGTWSFPKSVESGNSSNILKGDNGETKIKTEAEDSDEDDVVKKNEKNSSINREETSVNEEDRYAVIIPTTKSNTEIIDLTLDSDDEVIPNPSEATTAPPLGKVLPTTTSSTLLPSTNLHFPTPPSNPSTYIPPLKKQKTQGAITMPSFTTTNIKPTNSSQWLPPPNPNNSAHNILPLEQSGVFNQQHQQHIYKRVVFGNSNGPPLNFPNYLNQNTSNSLQQFYNSGSGMISSFQPLPVTFSPLAANPQINTFGVSGLSAVQNPATYNNTAQSNNTSNQNFKWKNNQTLNEIKVMRRYHLQKRDEYMKYNRIVGQITKLTNKISLLDPKDSFRDETSEMLLEKLFNLGIISQKNTLSQCSKITVSSFCRRRLPVIMVRLKMAETVKEAVTLVEQGQLRVGPHVITDPAYLVSRNYEDFVTWVDTSKIKRKIMKYNDKLDDYDLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYY6</accession>
    <name>A0AAD5XYY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminopeptidase P N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003221</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000214">
        <property type="protein sequence ID" value="KAJ3221698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYY6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000002">
        <property type="entry name" value="Xaa-Pro aminopeptidase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF1">
        <property type="entry name" value="XAA-PRO DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="7">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="432" mass="48934" checksum="EC5356FDE36E6F49" modified="2024-05-29" version="1">MTLLQYTPLTPAHRNNVFSKMVQHSGLVYLRGGVTQERLNTDTEINFRQESMFFYLTGVQVAGYELILDLSTKKSLLFIPRTDADHEVWCGKSPTLQDCKEKYLVDEVYYVDEIEAFLEKASEIHFSIAITESRVIKSEGEIAILREAARISGEAHIALMKKVKPGLNTERQLHALFEYECFRQGAQYQAYTPIVASGKAGATLHYTKNDANLTPNKDDMLLVDAGCELYCYASDITRTYPVGGKYNGDWKTTYEIVLETQKVVLNALKPGVKWEDMHRLSYRTICIGLQMAGILVGDTEELIENHIPALFYPHGLGHFLGIDVHDCGGYQPGVERIQEPGIRYLRMRRTLEANMVVTVEPGCYFVDALLDPAVKDPNVSKYFNLEVLERFRKNVGGVRIEDDVVITENGIDNLTGWIPKTIEDVEKIMKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ48</accession>
    <name>A0AAD5XZ48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex non-core subunit NAF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002776</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000195">
        <property type="protein sequence ID" value="KAJ3222038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ48"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040309">
        <property type="entry name" value="Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633">
        <property type="entry name" value="H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31633:SF1">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="232"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="450"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="632"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="237"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="512"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="633"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="650"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="758" mass="86037" checksum="AF5D2812122D00C5" modified="2024-05-29" version="1">MVTEKLMEDLDLTLDDDKTLNLTEESFKFVTNTAEKSPAFEKQRLKLPNDNLKGNELYSEEIIDVALNPFSLPENLDIQDFPLKDDIITDSVLLPDIKTNVSIKDFKNIDKVEISVNNVNLDNNCSVSTLFSDTKDIISVNDESANEVVNLLETTKTESNSATISDAVELGIPQNPINNHINTPADVYAENIPLKKESEEGEFVNSTVKVTNDPGNVMANVVDDTIGYLEIKKKEADSEDDDDEEGEEEGEIVSEVELSSDDDESKESDDDLVIKSSRVVREKLLIDADDEESVNILKTKNEIEKLPPVQKITMDISPDVALACIGEYQNYVDDLLIIQSHNHINEEAVADVDTVVFREDRSAVGQIFDVFGPVIKPLYSIRFNSKEEILNLNLSKSEKFFIVKDISKFVPVNNLKKLKGSDASNLHDEEVKEEELEFSDDEMEAEFKKQLKSKKKGGKLHINSEGGNERNEFTDNEEMFDEAEISDNKRRGRDRDVGRMEDSERKRKNFKKKIDNYTKRSNGFKEENFRVENQREGRDGNNGRGGRGGRGRGAYNNNRNQFSKGTRKNFNSSDIRQHITNNSHVIQTHYQQEQKFGQAPQGQLPGEVKFMQYPNQYQLQSIQTRPVPQFHSQPHLQNVNQGQQQPFQDRYQQSPPFSQLPQGNGMQSQYQYQISQQLPLQRQQLPGQSYLMPQPFQNHGQYNLYQQPQVFVQNNGYSVTNSGYSNTVSNGINNGYPVSGTNILDILDSIQKSGVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ99</accession>
    <name>A0AAD5XZ99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000506">
        <property type="protein sequence ID" value="KAJ3215986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ99"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026612">
        <property type="entry name" value="STRA6-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14752">
        <property type="entry name" value="RBP_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042006530" evidence="2">
        <location>
            <begin position="19"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="450"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="677"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="734"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="771"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="831"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1002" mass="116216" checksum="DE875536E696655C" modified="2024-05-29" version="1">MLPYSIFFAFHILLFTVAQDVNNSTAIQEESNPDVFSEITGDDIKDAVDHVESEFIDSLTLPDQSRIDASTRGIEEVNITRSIQTLLENINSLQDLHYTDLNKFSLSSCMDNLDRKESDFVINDPNFHNYKPNQTGSGDWIAQPSELWELTRFQAVFDAFCFVPIVNATNDDQPVVRTQSLTQVVNFPENLVSKIKTGSMQVNFRIGYYSLNGANVDLYFDFYYKNGSRVEIAENAFIGMSFEDSLNGRVWSNPVPVGAATMKIQIYGESSDLCIQYFGASLNKYRHEYEEEVLMSFVFAGMCCIIFILLTPFILFIQQCVKKEKKSIRMVDFVKRQGGTFFTMIFFAILALWLYRLNISFSVIMNYILKEKYQDAPINKFDPLKVYSGFVRVTFFLIGALLYLPILISFAHMTKNNRIAAILCFLNSCCFSVQRITFEYVSTSPRISAVDLAIVIGPEFAGLFYLIFMSFWGLAAPNSFERLFEFKANKDEKYVHDLLHENLHYFDVKKIQDGFFHSVKNRNSNGLLRKMKFWQKDSSIEEEVLKEERKFIRGDGPKKINSIRRQQIAFYNFDTPFPMKLIVLMTLAFTYQTLYTAVFGLHEINAQATCFQALAVGSSNKAYNLFFKTFLNIFGDIAEAISSGPLETIILDTLDIFYNEIRSLGEFVKRMVSIRSGSIYAAVVIVFLLISWNVWDLLVRFQFNLTRLRKGDYSWVKNGRNNPNLHMGNSIRYLGYQIGMSFISIRWTFFVFQMISYFIGYFIGFRWFREFVWAYIFGHGVLLIAIISSIVFRIIQKQIVCRFFLVEYEKPINLSTNFWLKRIYSYNLVEYLFLIINFVSGLAGFLGKLIKIFLVSGMFAFRNDYNFEYGFLDIFDDSSIYQSWVIEVHHYTNPILHQFLTICSSTVKETKNFNNNFTNPASLEVQQPRALNYGVNKQKLNNTGKRNSRARTRWFLLYTLVQNPGLVKYRSHTIKDTLLKNAEREYQKGLAAFKKNNLKMKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZD1</accession>
    <name>A0AAD5XZD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZD1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="26108" checksum="44ABDF75FE635472" modified="2024-05-29" version="1">MLKVNSYPTPKTEYLNYLPHKNKIQSRQPIHRSYSNPVDTTTFPKTIAKKTSNLRQQQHRKFCEVIQYSIFRILKKRKPNSQKDLSTLSLNLQSIFLNHYNIRFDREILGLSLLYFYRLIYTKNNEIDLFANFDLNKLFLICLSLSLKFLRDEKVENKFFLIYKIINNIEEMRFLELIVLNQLHFTLHCKRSEWLNWCNILNALELECEEFNIFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZW8</accession>
    <name>A0AAD5XZW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">PABS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_004004</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000272">
        <property type="protein sequence ID" value="KAJ3220805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZW8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017716">
        <property type="entry name" value="S-AdoMet_deCOase_pro-enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03330">
        <property type="entry name" value="SAM_DCase_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042011539" description="PABS domain-containing protein" evidence="12">
        <location>
            <begin position="21"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="13">
        <location>
            <begin position="237"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3220805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="499" mass="56606" checksum="0E7BB81FE582765A" modified="2024-05-29" version="1">MNILLWVLVVLYFFKYPTHANINPAVDTQRTNWVPPVSTKCSAQVPGEHQPLGKHYLVDLFDVDPIALAFLETDQAQLTVAEFIKQAGMTLLTSSAHRFPCGGITAVWLLSESHVSIHTWPENRFIALDVYTCGAVDPSQIVESFRKLLNPDRMVKTFVSRGSKHSIASGQVSKHDLQITRHKDIVKVNKESLDAISTPSVPKKKNFSEEKASKLGYQRDYTIKHGVDDKGNTIADICINGDDLVDDCIMLKNTVLLIDQNSPFQRIEVIDTNNWGRCMLLDRVTQYCENDNLIYTTELIERPFENFLEGAVSKGSQIKKLNVHMIGGGDGWVPSAILDHYSHLVDSITAVDIDPLVSEITQNFFQPVGKTDAFKDKRVQWIYQDAGKWMKTNAKENSMDIIIIDCTDHTAEAAKVLYTQEFYDLVFKMLKPGGKVSQQMNTNSPDYKDFFLEAEETWIKSGFRNLEKWQKYIPSFLGESVFWMAEKPDFNGEDSEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y036</accession>
    <name>A0AAD5Y036_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y036"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="30943" checksum="D2CB6D408215197B" modified="2024-05-29" version="1">MFECIAKDKRFSDLVRQIFNNYALSDGQILEELSAPLYTAIQKVHVSKVAHPGNPKKRTFFTQEMSPTEESIKLYEKVYDSLDADALKYDQRSTTCISDVKVMIYRYGKYDEFINELCPNHGYDSVSQSSVTEIAKHSCLVYLRTYDILLYYDRHDIINKLSKTIHEDCNNILLYSYGKYLEYMDDHYICHMHRYSDHPYIRDICHMIEYHMFEDILGKNLDTFRKNIIFSTENEEDYYYYDHEDWIGEKDEMRSAYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y089</accession>
    <name>A0AAD5Y089_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000230">
        <property type="protein sequence ID" value="KAJ3221437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y089"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="236" mass="26670" checksum="882517823594E589" modified="2024-05-29" version="1">MSIAPNAILCLHGYLQNANTMEHLCSKLSSTNNDVEFIHVDAPFTITSEEVNEFVNAFALKNGINDEESKKTLLRAWKPEVGDAKTWWKMDEYSFNYAGFEETILYLKSVLENQGPFVGILGFSQGATLASLVTSILENPDLFVTKINHPKLKFSLLFSGLKSRDQKHLKFYQNTIQSPSLHVLGNFDSTVDNSQSMDLTKCYQYPEILRFDGGHEIPDSTDALFSIQKFINENLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0F2</accession>
    <name>A0AAD5Y0F2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0538 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000289">
        <property type="protein sequence ID" value="KAJ3220589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0F2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018794">
        <property type="entry name" value="UPF0538"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18444">
        <property type="entry name" value="UPF0538 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18444:SF9">
        <property type="entry name" value="UPF0538 PROTEIN C2ORF76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10209">
        <property type="entry name" value="DUF2340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="156" mass="18154" checksum="4273B6CE5D2BD301" modified="2024-05-29" version="1">MSLQADNKVLPFNPIFSETERILDFNKVNLTTATITVRLIKSFEFRTVKNIILKDLNLNTLTLKGLKTLIFEKIKTTSGLKPYLNVNFDTLKIYTKAHGSKTQNLVINFEEDSKLYLKSENDDCNLIDLMIENETELSFFTLSDYEKYKLNPETKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y105</accession>
    <name>A0AAD5Y105_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">WNK3</name>
        <name evidence="14" type="ORF">HK099_005800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000047">
        <property type="protein sequence ID" value="KAJ3225975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13983">
        <property type="entry name" value="STKc_WNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001565">
        <property type="entry name" value="WNK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024678">
        <property type="entry name" value="Kinase_OSR1/WNK_CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050588">
        <property type="entry name" value="WNK_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13902">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12202">
        <property type="entry name" value="OSR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRH" evidence="13">
        <location>
            <begin position="66"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="533"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1057"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1127"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1057"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1097"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1134"/>
            <end position="1148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1435" mass="164677" checksum="ABA5026E85ABDD45" modified="2024-05-29" version="1">MKSFQNKLKYESNELMLLNKNMTCYINNNFYTYKNSKGSETKLNNQLEHKILSYSLNVLNKHFKNKDCLSFEKHFWQYEYCHNRYIRQWLEVKGVIYGEYYLGYYDNEESNEKILKKDEMDDSENGRFLKKRFFDGTYCPDIGKNRSAQVVFKCCTHDHIADVREFSVCSYVIEIHSPAMCSKLKESKDVEINEIECILNEVVVEHAENKKNEVLSGALNSDEVFSVVDFSKYCIKDNSFDHYCVKKQNEIVNGNHELSAFSKSKDKKLPIFNELTVEEDELVVYDKLLTVLGKKKLALQKKINDLSGKDAMDSVKDYDIFNKASYSTKKKNIKQSIQNYVSDMKFDSSKQNKELGDFFFNEDVLIEIETNLKNGKLAFENNYSMNLIENQIFKVADPNSLKLIELFKKILKRDKIKTKFSEEEYRIIKLELKNLKYLIKNESKKLKFNEEYLLKTKQQLLSKKKEDALIFEIYSFVGRNLEFNELNLKKLMSLFKLLKESSNDFQRSGTFDEEEDSDDENRVVETSPDGRFERYNICLGKGAYKEVFKAFDQENGFEVAWNHLRLDNFSKRDQTRILSEIRILESLRNDSIINLFSSWIAKGKDGKEKVIFITELMTSGTLKNYIKKTKGQIKPKILRSWSRQILNGLLYLHTRDPPIIHRDLKCENIFINGHNGQAKIGDMGLAAIKYRDHMSSVLGTPEFMAPELYEENYDEKVDVYAFGMVVLEMVTREYPYKECTNQAQIYKKVSSNIKPQALQKIADEKTRSFIELCILFDKNVRPSVEELLNHEFLADTGLCSLSGSTGSLTLISPIFSPKDTPKDTPVNSTSNLMENFSSFPFGDNNSSSISNISAANSPRFFSPILSSPMQNMEEILYTNTPAHITASFDVVDSDTHTFHITKHIDKENMENLLPDGMQDGILIEVIGEPSLNEVILQMVYCPKSSHSETIKFPFNLDEDTATDVISEMVQENLIHEQDEQLARRKLEAVIRKVLLGRRNNISNGPQYFQQDSNNFLVSDEKKTTDINLLPYNRHIFSNDFTHNKGLVNENIYQNASSPIRSPSTQVNNDVTDSRLLPPRLPVSQTSYSIPHKEKINSPPSINRNIFPTSPRRTATFNTLNSPINVGRNKRNFSDESSVSSTYSRPTTPNGGGYVINPLTGQLIFVHGEDPYLQPQIHQSNYPYNGLFTPYKLSDIKHHHPGGAGEQFPYLRGVSSSSNNSAKSSISSSESIIIPNGNGEFFEYVRSGRPVIPNPVVVTGEQFGGYSQHFNRQYIPLQQHIPQYPSEEAYFRQAQQPAYKPDEVNLEKFSKQQQFAENLSISTEEGCSVEKIKDIHNFINSERQSNKSSLTVDNLNVATNTTFSNIPIELENEFNSCLIKKDDFDESEKENFNLSALKKEMNEFIEVDNCEEILSGIVGMNCSTSGIEEVKGLGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1C8</accession>
    <name>A0AAD5Y1C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000182">
        <property type="protein sequence ID" value="KAJ3222289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1C8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF159">
        <property type="entry name" value="LD03170P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="1">
        <location>
            <begin position="151"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1260" mass="144964" checksum="08B59F32ECCE465A" modified="2024-05-29" version="1">MAQETPKAKNHMIQLDWAGAAFGQYLRTIYKEFNEDSELYGKNFSTAINLDFLGDDKEIDAISKFFIENCQEINSELVQDIKALECSPLREVLCILCFVLIRIFQSVGSYIVDVVFDESALEFSAESSYQVREFATKSNPVYQADIVCDKIKELMTSEAKYIRKMKLLENKYYCHLRKEAFKDESYSKSKNIMRCFPSMKLLIGQNERFLKELTSVDTIFFDGVEIPILKRVCEVFIEQVATFQTVYRSHFEDLDTSETYLRDCPDENFHLRLKEIENKCIKECENEEPEATAPTLNDLRIQAVQRLPRYLMLLSDISRYIPKEHENFDAFTKAIESVKTLLFNVDQQNALEKTKKLVAVLSKTFENEENKNLAYPMSIKYLLSELLVEGSCLTFFFDKKKKFFAENRTFLIQLFNDRLVFLVKTRELSDIKDENLKRFSDNNSEFELYGYIELSGVEVWLSRSFESPNEGGFTCIEFLLKILVTGFTIATSSKVHKNFEEVFKRNVNLQTLQRRKTIKNIFSAVKNPAFGKVAFGRNDYLPKNCERYDFFLPKCRNDSSSDIDNFIEFIEKIKVAIKRFEYLKDESNDSLKIYDFNKQQSLYYSFKNTRINFNNKRSKFLLIFINSINPIEAELEINSIKQKIVAENGEFNLTYSFVGWICQSTEGKFRLSIQSKMDMSRFYISTQHWYDETQFPSVCYHNISRCLKQIDTLVPQYLLPEFQTRQECDVNFFCSKFYQPQKVQPIYKKFEDSETALKANKDSSVTNISVKSNSSVLAAIKNFVSGRSRKVTEEKKLTREQSFASISRISRVNSTSSISADILVEAIVSEEFCVAVPDALATGNQKSPHQSGYSNIGSDNRRKVLGRQRYQSGVNFRNTTDPLQYRLVDSIEKFCNVEEAIEAMCEMEEELDLLSFLFSSIELAGPSIYEELSIFDDEEKLAAEISIRQYQCGFRTQNKFFYIVERLNCYQKLVLLKVLITKFSLSGKILNDADCTRFAWIDKIEYDNAVEIFSKLIDAFKVKKTKLASPTMQRKAQDFKNYEPRPSDFFLGKVKRNQSLLSIKEVDEGDRVIGSLSIAKTVKDLGTQDAPKLVSALFEHKNQIKNAEATETDCKIPGGTKVLSCCSISTSTKVDSSIHYSPRLKLLEDIVCDPFSVNVLIDADQEGNCILNNENCCEKKNGQVDLSTQFSTTSLDTFVNDELAEIAKSADCIKVEKTCQGSKIDEMNQKLIILIENGKKELTNSVATLTGGDEVKINFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1G2</accession>
    <name>A0AAD5Y1G2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000175">
        <property type="protein sequence ID" value="KAJ3222453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1G2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004771">
        <property type="term" value="F:sterol ester esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025:SF3">
        <property type="entry name" value="HORMONE-SENSITIVE LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="1">
        <location>
            <begin position="107"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="1">
        <location>
            <begin position="332"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="548" mass="62538" checksum="EF39209CC16D9CD7" modified="2024-05-29" version="1">MDAGFLTAMHIKPKFLKDFLSIVFTAFYLIYADKADEKVRKYRAVATFHMMRISWEKSDNPYLRMLTVFDRGSPTSFPDDQLNDIKARIYFHGSKEELVTASKLIFHVPGGGFVTMSPRCHDDYVSNWARKTKVPIISINYGKAPEHPYPCYDAYRAIVESNGKVIGFQGWVGKDGKKVSPLKIIVTGDSAGGNLATGLTLRTLEPTSVLPATPCPAGLLLIYPCLSLEISCWMPQEQMHMIRAESVKSMTNIKSLLQAKDHFITNEEDSPLAVPEAPKKIDVLTDKVDRDDTGITGWMKRRRASKMKEKNFEPCHSTPIIRSSLSMTSRMSYFQDRILAPEMMRAMALLYLNGSPIPYNIQEDIYLSPINTPNDILERFPQTFFITGEKDPFVDDTVVFAAKLRQAKERKKNRIKGGFGIKRVEQKQKKSKKTLEEFGVRVKILEGISHAFFNMMAFLPETRQAITLTSEWFLEMLGVNVENEEEFTSSSFNGHLSEELLYNSSDDGFDESIDMERELSIVKEKKLMQRRREQLSEQHLQEGNSDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1M7</accession>
    <name>A0AAD5Y1M7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000451</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000110">
        <property type="protein sequence ID" value="KAJ3223967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1M7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041965898" description="alpha-amylase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="11">
        <location>
            <begin position="285"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3223967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="744" mass="83397" checksum="1CEE5AE3637B126D" modified="2024-05-29" version="1">MNKVIIFIHILLFCLTASAPTTIVLNSPVFQNAQNVFLAGDYNEWSTNKNRMTFNEKWTVTVEMNREIKQQYKFIVDGKWTLDDFAPKENDGRGNVNNWLAPLQKETSSSSLTTTTSLIASSTTTSFTTSIPSSSSTNPGTNPTELPGCQNYNGKDSCQGQQTEYDISVEERRWQTPSRNSSDYVSSYQDYSDLTGYASFEYSNDRKSAVVTVKAFTRDPNAVVLVSFNGGAATTTNTFQATSDMKEDLTIKLTIANTVQSLTLDPLNFLWQNNVVNSNFDGTKGAIVELLGWPYKDIAQECVFLGKAGYTGVRIWPANEHIQTDKWLGENNEINNWYYVYQPVSYRLHSRMGTRDELRSMIQICRSHGVRIYADAAFNQMTGGGNDVLDHRNQKGNFCETWGGKEATAGSPYYTPNWTYKINQNTGKRAALEFPAVPYGPSDFHCERAMTAWQDPFQLQFGWLSGLADLNTGKPYVQERIADFLVDLLSIGFSGFRIDAAKHIGPNHLAKIFSILKRKLGGSDLPSDFIAWLEVLIGGEKDLLCCNPGPYNWYTGNDELMKKAGLSDNDIYKVKMWSADYPKEMPICGNWILPPSRFLVQNDDHDQMFGGSPRDMQSFGSVLATAKDVNSHRNFEVNLFNRRDHDWKFRAILSGFSFTEKGAKGFPDGKSDCKIYKGNQSSCNSVPRAQAFVAESCGYFNGGVFKSNSYSRVHRDLKIVNAMRNWMGLNSVGPSELGLPSHCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1R3</accession>
    <name>A0AAD5Y1R3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000103">
        <property type="protein sequence ID" value="KAJ3224133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050872">
        <property type="entry name" value="PPR_P_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128:SF329">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR DMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="230"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="438"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="794"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="896"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="931"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="1046"/>
            <end position="1080"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1404" mass="162427" checksum="6CDD5B687E426D3B" modified="2024-05-29" version="1">MICSSKSTVKVLNFIRTAGSLINNDIKTQKIPTTGKFVRTFSDLKEAEEKGNNNNCYSCNLNKVSESHYITKDNNGDRNIPATDNVIDISTKCFPDCKAVKPITKKEKSYPNLSFLENFQRNPDVNKFSLTKNPSIFDFEKAFIFFSGTKDIHSMRLYFRLLHQCNLKPTKLIYHCIMEAENDVAMKEKYYREMILTQTTPDEFTFDILINGFENAGNFTSAEVYLKKLDVITYTNLISWYAEARNLAKVRFYYNQMISHFIVPKMSTVDFLVSAYLDNNDLENSATVLKQLLQVLEQSKSIDLFKNGKDYLKFYNTLNALNIKFPTTLLEKVFNALRQFEDLSPFNKLVEIIEGEIFNGFSNEHNLLLKNLILLGDLSKLEKLLTTKHLETVLFQNFSFIEMLKEMIRFKSTNANSFKVNSLNDIVLCLIKFFGELDLHLTEMLVNYFCENRMMEEAWFHYERMLSNNVSPSYEIYISLFHGFTASNDIENAVKIKSLLKSIGFNLNLEGFNRILQLAVDVSRLDLIKTFKEEMKVLGYEPNCTVANSMSKIYFETGDLESQIDLFNAYQTWKVVMEPEFFLYCGIAAINSLNWTLTSEVIKKLQIEYPGHDYLIKIVKIYEDNFSLFNCYKKMDISGTWKIYNNFRKQNRHPTPKLHTLILTRSIRSSSIDDIESVLDCLRDLLECQDAKLSIFDYEILIKKLILHDNVDLVIKTMLLYSKHDVNMTSIQNNKTLSYLIKRKKTQEAELLFGCMLNVDTVTFNTMLSCFKNRPIFLLENYVNVLKKKKVKLDTYSYTELMDSFFCAGEYSKVTELFNEMQKNGLQPAMPTFGVLVKSQLAENNIAGGLKIYRTAQSQDTNSTVISLELMKYFLKMQDYNMVKFIFESIPESDLNVQLFTKMIDSRAKLGDATAAENYFDAMVSKGFSPDLFTYNTLLSVYCEVGNEFKAVKLVQKIQSHFGLQAITVNLVLLLYVKKVDSISALKWIKERKIEGFTEDVLTYLTLMKLYASLGDLKNLKIYHKLASEKMKSAEDAVKYHNHFNAIYINSMFLNCYAKSNSTKEAIELFESLEKKSLTPTVGMCTSLIEAVGSSFKFDLLQIWTEKIIAKQKVQLDLQFFNTLSSQFSKLHKIDVGIKKIFEFFNIKDFDLSEFKFFGSPTGNKFNEIMKLNARSRILENSITGKSYKFRNVMLEATVFNPFLSYYADSANVYNMYRVLILMKKLNLKPNVTTWAILIKGLALAKKHNLSFDIFKALTAKESQFLPNFPILIEPTVVNELLIINVLDSLKFGRLFSEAKIIFMDCVNNENLSLGPNFLTTYLELLCFAQKYEEAFDVCASFLHFNKNSNEYLKDKKPDFFNFNNVPRIKPDLKTLKNLEALLEKSQKHLELVNIVKMWKKSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1R7</accession>
    <name>A0AAD5Y1R7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001617</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000148">
        <property type="protein sequence ID" value="KAJ3223002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1R7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057939">
        <property type="entry name" value="TRF2_HOY1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24818">
        <property type="entry name" value="PH_TRF2_HOY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="172"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="174"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="629"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="629"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="691" mass="77043" checksum="CA3D314BB5F36A10" modified="2024-05-29" version="1">MDHQVIINTRAEDHVRVSYDLILIKKTLKDPIPKDGLRKRRQKQALAVRLAKSKKSTQRKIKIKNFYFSRVKTFRMDSSSTSTTSTANPTPIPSANSTPTASLASSNNSSVNHLDNLANTNSIESFFKPSSPLTNECSNFLINLQQKDNKSDNEQQIDDQRKKSISVDSIDTANQKKRTRASPDQLAILEDTFLQNTSPNAKMREMLAEKLSMNERSIQIWFQNRRAKVKLLQKRAQSTNGATNQRMFQPNFAFPNQPPFNSQRSNSIDFNNYSGIRNGLSQKPPNAIISGSLLLSTDTLSIGTWRRVALTNDDLLCSVSLSESLIRWQIVESSNRFKLEFPISSIISISLETVDPTQLQGQLSVDLLQAPQFFMEVNNGQGIVWTQCRDFTEGHQATSIFQHVLTGPLNSLKTELLSLMNADQYFKHIIHINTPISSGSLNSVSSLKRPSLSSGSPIDELTAFNMQRRGSCPATIFDVNSPSFKLRRGSILDHPSPLTEATNLDFDSPIMGSPLNLPLTLSPSNPSMMFSPNLDAAFNQLHMLEDFNLDHNFNSPNSNFKNKQHQNFNNIQQHLVSNSNTVSNTTNCKNNEMNSNNNFNINLHSVNNNNNNNNFQGMLDVNIGLNNNVSGNPQQVHPAQQDGQQTKKEVNADGTTSAGNGALPNTDFLFDIAQFLDSTSEMGFNDNLISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1Y9</accession>
    <name>A0AAD5Y1Y9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008234</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. Reversibly leaves the enzyme after glucose depletion, causing the catalytic subcomplex V1 to detach from the V0 section.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the V-ATPase C subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000089">
        <property type="protein sequence ID" value="KAJ3224553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1Y9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14785">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1460.10">
        <property type="entry name" value="subunit c (vma5p) of the yeast v-atpase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1180">
        <property type="entry name" value="Vacuolar atp synthase subunit c, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004907">
        <property type="entry name" value="ATPase_V1-cplx_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036132">
        <property type="entry name" value="Vac_ATP_synth_c_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03223">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118203">
        <property type="entry name" value="Vacuolar ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3224553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="385" mass="44011" checksum="8D49393FC8013007" modified="2024-05-29" version="1">MSSLYWFISAPGSPTKKDTLNKVKEKLESSSSDLGEVLPINLPDFKVGTLDTLYVLSDELQKHDASVESIALKIAENFKGLLQNNIDAWKNSLTVGDKSVDQFLKTFQWNTMKYRVDKSLKDLTDVILQEVNSIDALMKNKIQAYTQMKGQLQSLQRKQTGNLAVRSLNDVVKREYFVLDSEYLTTILVAVPKSLVDDWKAKYESLTQMVVPRSSQCIAEDEEYALYTVTLFQRVVEEFTIKARENKYVFIVRDYKWNEEQMQKEKKELSEAGASEKEQSATLQRLCKTNFGEIFSCWIHLKAIRVFVESILRHGLPPNSQAMMIKVKPKHARKARDALNALFAYLDVGGNAKDKGYEGMEESLTMLIGDKDYAPFVLFKIDTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y204</accession>
    <name>A0AAD5Y204_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein 135 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y204"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF6">
        <property type="entry name" value="GB|AAD46013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="436" mass="49975" checksum="873A6105FE882E4A" modified="2024-05-29" version="1">MKETEKNPKTKNADTIEVFIRPKVQSAKEIFPHALRVALKASGFGSFFSSFTFLWKFTDDLLRFLRKKDDKYNGFIAGAVAGVSLLCEKQDRRVTIAQQILVRGLQSVYNGLKSRELFHFHHGDSLIFILGSAQIMYGYAMQPASLPKSFYNFMVKTAPIPEMILGLNRKIVRKIPIENNLEVLNSLQEKFKFTKKHLASMETLDLNKVTALPCAVLHPGMDSCNKFSFGVVKKVFFQILPVYLSLNFAPMIALKFKSFIQNPMKLATKSFGNACRSSIFLGAFVAGYMYMCCVHRNFINKTGLHFENKLLYFLFGVCCSSSIFLEHKNRRSELALYVLPKALDSLYRVMYNRRWMVNIPHFETAMFSLGMGFVISFFQSEPGAMSTMIYRLLYRINILIEDNEYKRTVVKKVRSHHIVASDEEFESGDCKPLLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2B9</accession>
    <name>A0AAD5Y2B9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007094</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000066">
        <property type="protein sequence ID" value="KAJ3225268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2B9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060628">
        <property type="term" value="P:regulation of ER to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007528">
        <property type="entry name" value="RINT1_Tip20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520:SF0">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1 RINT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04437">
        <property type="entry name" value="RINT1_TIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51386">
        <property type="entry name" value="RINT1_TIP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="226" mass="26391" checksum="8BC7538649894741" modified="2024-05-29" version="1">MEMSELNSAGDIFDEFITDYESVCEQLIEFIASECFEKFVESSWKYLKNCGSVWISVSNEEVEEITKELVEPLEYIKKFSDEYFLKLPRKINLNVNLQILKKLDEFLFENLLLLNKFSISGIRQFSFDLNYGFNNFSGFFIGGVSQNLFKIENYFRKCREGLTVLEANKNSILNILSELKRVEQEDEAKESKFVVPKKSMMGLENIGFYKLSKSELLNLVDNRTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2W6</accession>
    <name>A0AAD5Y2W6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="2">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_006923</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000063">
        <property type="protein sequence ID" value="KAJ3225382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2W6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:proton-translocating NAD(P)+ transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05304">
        <property type="entry name" value="Rubrum_tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000028">
        <property type="entry name" value="NAD(P) transhydrogenase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026255">
        <property type="entry name" value="NADP_transhyd_a"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00561">
        <property type="entry name" value="pntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006942">
        <property type="entry name" value="PRK09424.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160">
        <property type="entry name" value="NAD(P) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160:SF19">
        <property type="entry name" value="PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="12">
        <location>
            <begin position="4"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="11">
        <location>
            <begin position="123"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3225382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="303" mass="32891" checksum="225FB140AB7427E6" modified="2024-05-29" version="1">MYSVKEVLIQKNAGYLAGWNDEVYKRAGAKIVDKEVWESDIVLKVRPPLVESEINETEFFKSGSTLISFFHPSQNQDKIKLLQKRKMNLFAMDQIPRISRAQSFDALSSMANIAGYKAVIEAANVFGRFFTGQITAAGKVPPCKILVIGAGVAGLSAVGTARRMGAIVKAFDTRAAAKEQVESMGAEFLQVEIKEDGSTVGGYSKEMSPEFIKAEMALFLEQCKICDIVITTALIPGKPAPKLISKEMINAMRPGSVIVDMAAEAGGNVELTKPGKLFVTENGINIIGYTDFPSRLPVQSSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3A4</accession>
    <name>A0AAD5Y3A4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005327</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3A4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="3">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="335"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="466" mass="52445" checksum="812510700D573F56" modified="2024-05-29" version="1">MSTYTVKSSFKESVRKFIVEEVGDFKTFEAKIKGVHDIPLQKKVTLSYLDEDNDVIETVEVSRESIEEEDYFEIKYPEVDIPYNETSIPLNEVSITDPFVTISEGGNVHPVEEKIEKGKEKEVFFETIMDSNDIKKVEEVNESTSTGKPIVINFTSGSNTENPETLDRNNEKYSASSESENKYHENSSHQPKQEYYKNSAEEFASNLESLINQLSTELPPILTTFAQQMQKIIELGISSAVNVSAGATEQAKKEGSRYYEQGCKSFSSGKESCEEVRKEAWKMSKEAQKEALRMAREAEKEAHKAAKESHRAIKEAHKAARKNFSKLGNSFGTDFPFTHSPGSHHHQFPGQFPPPVPQSGPSYFFSPPPAPEAPPAPEAPFPPSTPFHTSTSFGSHWHINGDKTRPFFPDVTETETKNPEMVKIDDYEKQNKTLLAMGFGNSKLNQILLKEFKGNMETVIDMLSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3C7</accession>
    <name>A0AAD5Y3C7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005054</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a heterodimer with SLX4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SLX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000038">
        <property type="protein sequence ID" value="KAJ3226346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110085">
        <property type="term" value="C:mitotic actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033557">
        <property type="term" value="C:Slx1-Slx4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903479">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21206">
        <property type="entry name" value="CH_IQGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10455">
        <property type="entry name" value="GIY-YIG_SLX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03100">
        <property type="entry name" value="Endonuc_su_Slx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027520">
        <property type="entry name" value="Slx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF14">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="GIY-YIG endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="10">
        <location>
            <begin position="44"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="9">
        <location>
            <begin position="516"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="GIY-YIG" evidence="11">
        <location>
            <begin position="1197"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="616"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1043"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3226346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1557" mass="178079" checksum="08D2BEA89D1C4E26" modified="2024-05-29" version="1">MNETLNEATDVTGLHGRKKLEKGTAKDSNWMDAERKNLQAYEYLCHIGEAKEWIEACTKETIASIETLEEELRNGIVLAKLARSFNSKSVGKIFEDRSKLQFRHSDNINFLLTAMRATGLPEVFIFETLDLYEKKNIPKVIYCIHALSHLLARLGLAPHIKNLVGKLKFTDEQLDATNKSLEQAGVAMPAFSNIATALEKELPPLTEEEMRRQYLEQNMAKILKCQAFAKGQQAKKKLAELRQINMQKRKAEADYQKKVVICQAEVRMHQARKAFLTRQKYWQQNKKAVIYTQAAWRGLVARRAYKERIERFKAGEGAIIKAQAIYRGKKARQAYNQRKQFYKDHLESIIKIQSMWKARHMEKAYKSISSLNNPPVSILQEFLHLLDDSDNDFEEELELEKLRQLVVKMIRDNIQTDSEVGELDVKISLLVKNRISLEEVVHSTTKKKKQALSEIALNENQSNPFSLKGGDKETRQKLEFYGQLFYLIQTQPVYLAKLLFSMNKKSGGTVTKLLENIVLALYGYAQNNREEYLFLNLIKECIHIEIEDISNIGEFWRANPLFIKLLLHYTRGAKERQFLRDLLQPLVKIVLHNSTLELETDVMLIYKALIRDEESQTGEKSKRSPDVTPQQAAQDPEVQKIQSAHFAKLQEITDQYLEAIIASLPKLPYGLRCIGMVLKETLKKKFPGNDDEINKIVGNLIYYRYLNPAIIAPEAFDVIEANISPIQRRNLADVAKTIHQISVNKLFPQDGTHMDQMNSYLAKSSKKLSNFFKDVSSNVLTAEEQFCTDGTIDVGSGQKLSIYISPNEILQVHRHILDNLDDLTKDKNDPFRQILNDLGTPPPAELDRPHGGEINLVLTNRINNLTDEDKNVRVKTRLNETKRLVLAIIRIQSGKNLQDILETPTTSREEDLFTELQNRETQRQQEKKEIIEKRQILDGIAASSVSLNTSPLGGVAKSDVDLNPKQLSKSDGMFKSENALSSSSNNTLYRGGDGTSLTFAQLKKKAKENLVLLEEDGAVKKSTHYQDLLNLIARDMLNKHRRRSQRSREISTLKNTLKNLEEKKGYLEDQKKSYHDYINACISQLGNKKGKGKKTPLPFTRQYYHMRELQKTGKVPKFGSFKWTADQLQKKGVLISVDDYGPRQYKQITLTISSDEAGVFKVGASFLGISLPEQMELRLEDLLQSQYNGVQVMTLFDMAKVNLLLSDFNKRSTYIGSTPNPVRRIRQHNGELKGGAYKTSKNRPWKMILVVYGFQNKIQALQFEWAWQNPNLSRSSSNDNLPTNLQIKKAHPKPTKSARYGLKNNIAALCHLLKSERFNRLPLKVNFFESELEKIFDLHYFSPIQSDIMSDSSSDFESSEDEDGKKFPLHLWKGYLNDLTELPIKTKSEISNNGSGSCGICSKSFENSSVVLRCFDANEDAQLNERKSRCCSFKSHLICLAELFLKKEEENLNFLHSKIRHKKKLKNLNFYKSDQLLPSRGECPICSKNLIWGDLMKQSNLQKQVDIDGCSSDEERVEFSNFDPNDYFSTSLQVSSQLEAVNNVLDDLSLKSIDQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSE8</accession>
    <name>A0AAD5TSE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002119">
        <property type="protein sequence ID" value="KAJ3199417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSE8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007246">
        <property type="entry name" value="Gaa1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04114">
        <property type="entry name" value="Gaa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="153" mass="17425" checksum="998886EEF8366674" modified="2024-05-29" version="1" fragment="single">MYICTFLFLKGISDWLRSNSSDKIKPVSKTPQQLPEELVKAINATSDEPDFQKKKYFIYSEIDQPFSTESRPFFFPIVIFLLSHLIGCGIMLLPWKGSYFVFASIFTTIIGTKLVVPLIIQLIETTTSAKQRRQELSLLKSFICTELSLALSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT53</accession>
    <name>A0AAD5TT53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001692">
        <property type="protein sequence ID" value="KAJ3201657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT53"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="22134" checksum="6F9D600D21454795" modified="2024-05-29" version="1" fragment="single">MSVLLNSDFPNSSKSEQLSFKIHDRTKSFGYFFQTFKKEKVTVVFNGEYVSSKVLKRIIENFADISHTAKYNSKNSSLREFYLTNLEAIIKVKNGNFKEHVTQLISSSITRLQISRYGDDVLRSELADACKECDELKLEKEVVISVVSMVKSVKSKIEGKLHDREVTVNLQKEYDAAILEQDDVLQTTGEYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT57</accession>
    <name>A0AAD5TT57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001885">
        <property type="protein sequence ID" value="KAJ3200530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT57"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="141" mass="16475" checksum="D22378165796436F" modified="2024-05-29" version="1">MSSTSTQTLVLSESSQNSTDTLQIQKISKRLSKQLLTHQKQGEIPYITEYLVANINNEVTEIFETWSGSEYDRKEYQAQGFPTMPTSFFGAKEAWFRIKSKYNDYKETQETKKIEKKNKKRMSMEIKQKNQQDGLKRSLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTB2</accession>
    <name>A0AAD5TTB2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001588">
        <property type="protein sequence ID" value="KAJ3202323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTB2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="85"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="302" mass="34745" checksum="CD67C221CE67B2D9" modified="2024-05-29" version="1" fragment="single">MRCDINQNSMLPSLLLPALKPKNKVDIDRKFELEKINNTVVVKKASTIRKPVVYKSPEEEKLVKSSTIKIQELPPLQKELHVGEWHLGAVLGKGASGIVRCGVNYITGEKAAIKIIKRPQIDHGKNRHEEEERVQRQEMYLIREVFIAYSLRHQNINRLRAFCDAGLFQLYVKFLKDNTTSAKTALFIVTGIVNIITSKENTVGPYIYPSNGTTGNTFVQSLINTRLIYELFNILLQQEQQLEVAKLELINLKEEDIEIDSNDIEDTYQKTSALKNDKKKNDENNFNKINKDLFLNFENRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTF6</accession>
    <name>A0AAD5TTF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Vacuolar protease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PEP2_5</name>
        <name evidence="13" type="ORF">HK099_001949</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001601">
        <property type="protein sequence ID" value="KAJ3202242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTF6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000008">
        <property type="entry name" value="Cathepsin D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000002">
        <property type="entry name" value="Vacuolar aspartic proteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042171843" evidence="11">
        <location>
            <begin position="19"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="12">
        <location>
            <begin position="111"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="343"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3202242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="558" mass="61035" checksum="9F4BE9EB9538DF63" modified="2024-05-29" version="1">MKLKILLICSIFIDAFSAATINNNKRKCYIPHAQKPSHNENYITLNLHTTSNEHLKPLTKLEFEHFVVTNKLVSLKKFNLLDDEQIEVKKRELNLEKRQNLALVDFKELLYYASIKIGGQNFNVQIDTGSANLWVTSSKCGNCGTTNEYDSSKSVTYKPNGEKFIISYGSGQVMGFLSSDTFEVGHYSLLDNTFGEATSETSEFSNLFIDGIFGLAFPEYAVNKVLPPFQKMLQDGLIKQNLFAIYFGGLGFGNESTITLGGVDESKYTGEITYSPVTRKRYWEIELQGFKISSTNLPVEGRTAAIDSGTSLIIVPVTDFKIINEALGGQYSTFFGGSYQFDCSKIQVLPVISFIFGEKEFSLKPEDYVARFETPSFKLCSSPFMSSGSSKSMWIVGDSFLRSYFSIYDFENSRVGFATAATKGSFATPTNSAFTTASNIATASIVIPTSTPTSSTAISSIATSDKPTPSAITSSLVASSVITLATSPASQVTSLSSTTTASPVGEVCLHDLCTLGKKLSRTCDPCVPLVCKKKVLCCRTDWSIECINFAKSECGLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTK7</accession>
    <name>A0AAD5TTK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001533">
        <property type="protein sequence ID" value="KAJ3202696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTK7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="17694" checksum="C2111F4A7A8BBDDD" modified="2024-05-29" version="1">MDMKTPQIKMDETEKEIKNIKLLLEKKNDELDKKKKDVNVKKKEIEDYIEEKQTPSKLLFSTGDRWFLRLDDELKCLQIDYDKLLSVIIEKEKQLTLLMEKEFANPNENLPKRVKKDNQEVVPPHDKPAPLLKNRSFEIGDDGTVENLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU22</accession>
    <name>A0AAD5TU22_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001270">
        <property type="protein sequence ID" value="KAJ3204736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU22"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01838">
        <property type="entry name" value="Isoamyl_acetate_hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045136">
        <property type="entry name" value="Iah1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14209:SF19">
        <property type="entry name" value="ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="182" mass="21077" checksum="40A8149BC457FA26" modified="2024-05-29" version="1">MANYYVRKQDVLNRGFAGYTTDDTLQILNSILIKDSQELSLITIFLGANDAVIDPPNSNSHFVELDEYIDNIRYMIHKIKDSNSQTRIILIAPPPVDERKEHYRKNSSTINYRNACLDLSKDLNVPIVDTWDLFKGKDENLLYTDGLHLNKLGNDLVFEGLKSVIKQNWPDFQPKMLKNLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUI2</accession>
    <name>A0AAD5TUI2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002099">
        <property type="protein sequence ID" value="KAJ3199503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUI2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="194" mass="21869" checksum="B1C8B5C44FE8BB35" modified="2024-05-29" version="1" fragment="single">MLFKRKGGSSSSSSSGGRSSSSTGRSTSSSTTFRGTGIASLKNPIKPGGFKRASSKGYSSTTSRSNLFGYPFWIYYYDEPQRNVHQCVDSNRDRHCFIQSKSNNSRYYGIVTDGWIDSEKVIPKTFLNFGFNVNETISDNCRWYRTNEIYDQDDDLIETIYIKDFNSNLTANSLYVNNPEVEQIQNILLNISSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV99</accession>
    <name>A0AAD5TV99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001823">
        <property type="protein sequence ID" value="KAJ3200859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV99"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964:SF113">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="48"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3200859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="22521" checksum="D060691315A3E485" modified="2024-05-29" version="1">MNTSIQPNQSKSFLRKGYKSVPPPIEKSDSLHLHEQVDHNELHDNPSRIICIAVDESDSSQYSFKWALENFICKETDQVFLLHVRPYVSVPTYLSPVPMLEDKETEYELDQCNRNFSHELIRDFAKDLLNENIKCRGFALRGDPREEIVHKVNELNADVLIIGSRGMSTFKRMFIGSVSDYCVHHCHCTVIVPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVB7</accession>
    <name>A0AAD5TVB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003422</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002240">
        <property type="protein sequence ID" value="KAJ3198884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVB7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="146" mass="16726" checksum="A454E22DE62AAC74" modified="2024-05-29" version="1" fragment="single">MHNSGFYFHSLDLDVNTIDSDIHISPSVLTEENNYIKSIGVDDTDITFLNTQEPALKKVLTSFAKVFEQPPHTDHIPKRPHFDQQINLQTNFKFPHYGPLRPMNEKHLAALKVELEKLLANGRIRPSTSTHRSHVMLVPKKDGGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVD8</accession>
    <name>A0AAD5TVD8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000172</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001024">
        <property type="protein sequence ID" value="KAJ3207887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVD8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959:SF0">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3207887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="29664" checksum="13F83B21FC17DE08" modified="2024-05-29" version="1">MPDLTTLYYEILDPSISTKKDDSNLKQKQTVAKSNTQNTVEPYLSEANQILNQIENLNTYLINTRISYLNLHSLVGNNNFVKVLNEREKDEIDTQTKLIINGCFERIEKLATVAGWDADFDSLLSETRKNIVFQDGLDTEEESEDDLNLTQQEKLMFESENEQIFSELQSTLDVVRVTTQSIQEISNLQNQLVKLLQLQSEKIELIYEDSYKSVGQIEDGNKRLLNAEKNFGQAKKWLLFFLIFSTLIILFLDWFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVF4</accession>
    <name>A0AAD5TVF4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Anti-silencing function protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RPS5_3</name>
        <name evidence="15" type="ORF">HK099_008355</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ASF1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000905">
        <property type="protein sequence ID" value="KAJ3210149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVF4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1490">
        <property type="entry name" value="Histone chaperone ASF1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006818">
        <property type="entry name" value="ASF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036747">
        <property type="entry name" value="ASF1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003106">
        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04729">
        <property type="entry name" value="ASF1_hist_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101546">
        <property type="entry name" value="ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 11 15" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="14">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="13">
        <location>
            <begin position="732"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3210149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="891" mass="102300" checksum="62165E7EF9AA2F7D" modified="2024-05-29" version="1">MTVNAIPSQVDYFSYNFDLFDLHTSWKYSTRHKDSIVNGRRLENASWRKFFQTKYKLQQIHPYELNWQKESDVIWLYGPFHTYDPLPILEAQYAATEENSSCTEKSIKSEKIPICKENLKPVLKKRSDEDDFLQMLREIYLENKRLKVRNTNLKCTDVFDENSDADLSPTTLMLSIQKVESKTKLCKKHSMNSRDDASDSPTERPFFYTNSKSLPQIYKRGKRVERINTSADSSQPTYENCDSSRSPTYSKQIRFSKNVEKRLYVGEDDIKIPKIHNFRPHKIKIPMKRSLSPSNSTSNLLDLVVKCTKEGNNDNGAEEDIGSIKTKCGDKDSISSPKSPYKIDSPTGRGVKLNFLLDESDDSDDETSTLEDDGKSDDEVNFQVLPKGVDKDVWEKIIPKRNVVRNESTKSLNFLNSRNYLNSNSNLIALQKFENNNQMPVPEPTAQKNTTTTLRTNMRDTHRSRNPTGLMTQQQLDEYYAALHHDNDANNLEVGEGYTRRLMDVGANAIELGGWLARSAVRSVGVTFQNIEVLNNPAKFTDELSFNITFELNSPLKDDVEFKLTYVGSPNSEAYDQTANAPIPEKIPHDDVLGITAILLTCSYQENEFIRIGYYVNNEYENPELNETPPLKHDYQQIIRNILVDKPRVTKYRIQWDDVIDDKAEFQKDEKLNNENIQEDDVAMAMDNENDLDEEEEDDEDYDEMDNGANKWTYEDVEVKDPALTDYLQIRHPVYLPHTAGRYQQKRFRKSQCPIVERLTNSLMMHGRNNGKKLMTARIVKHAFEIVHLLTDANPVQILVDAIINTGPREDSTRIGSQGTVRRQAVDVSPLRRVNQSLWLLTTGAREAAFRNVKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVS7</accession>
    <name>A0AAD5TVS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Guanine nucleotide-binding protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GPA1_5</name>
        <name evidence="7" type="ORF">HK099_002743</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001936">
        <property type="protein sequence ID" value="KAJ3200277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVS7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="37"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="107"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3200277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="22602" checksum="51D0E9B8D4A4507D" modified="2024-05-29" version="1">MEKYKPSDQDILCCRRVTKSITETKIVVGKQKLRIFDFGGQKHLRNFWAPYFDDKNNSIIFVTAISSFDQKMEEDEENNRFEDSLKLFEILINKDVLQKVEFILFFNKMDLLIEKLKVKKIKDYITDFEGDQNDLKVTKRFFRKKFESVSQKPLKYVHFTSCTDSKLMKKIIKDVLEIIISGCLDDIGLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVY0</accession>
    <name>A0AAD5TVY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008271</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BUB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000897">
        <property type="protein sequence ID" value="KAJ3210316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVY0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990334">
        <property type="term" value="C:Bfa1-Bub2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010948">
        <property type="term" value="P:negative regulation of cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000035">
        <property type="entry name" value="Cell cycle arrest protein BUB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000026">
        <property type="entry name" value="Mitotic check point protein (Bub2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF263">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BUB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="7">
        <location>
            <begin position="230"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3210316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="500" mass="56948" checksum="FF1ACCACBD47A54A" modified="2024-05-29" version="1">MLRASKSSSSTNSLCGDSPLDRKKKLLASPQRPAWNSSTSKHQLNSKIPYKLQKSQTIEQTKVIKKAPGKVPTTPKCTNQTNKYFLNIDIPKEAVREENLISSIKTSQSHEELKKIPIKYYGGDQNFTRLPVTPKRRVFSLASSSVSSHSTTFSPLNCLNSCNTASEQIIFASFSNPVPSATSLVLAQKYESVLTKRNLSDRELKDSLKIIRKMILQDGIPTLLMEKENMAVCTLRGKIWKILLGVYKVNAKEYTDLVEKKESENFDKIKNDCFRTLKTDKNFLFKVDFDMISRVLNAFVWKTKNQPVSRLINLKYSYVQGMNVLAAPFLYVMPELDAFYSFTNFIQSNCPLYVQPALEGVHCGLKLLDKCLKVVDLELYKYLKNKKLNASIYAFPSIMTFSACTSPLSEVLKIWDFLLAYGFHLNILCVISQLILIRDKILVSDSPMKILRTLPDLNAKLILRVTLNLIPQLSEDLYDMLVRHLFDPMIYDVIINDSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW37</accession>
    <name>A0AAD5TW37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000932">
        <property type="protein sequence ID" value="KAJ3209592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW37"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3209592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="98" mass="11691" checksum="5A8B5AFB5C4E1FC4" modified="2024-05-29" version="1">MPKLQIKINKEIDEVNEEQKENGIELLESEIISEKQFRNFEKDPEFLKLVRDPILQQTILTLEKDSNKEILYSTLMKTNKTFVDFTDYILQHLDEQCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWT2</accession>
    <name>A0AAD5TWT2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000744">
        <property type="protein sequence ID" value="KAJ3213108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWT2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990431">
        <property type="term" value="P:priRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990432">
        <property type="term" value="P:siRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02325">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF22">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="598" mass="69420" checksum="44A8AB06FE21755A" modified="2024-05-29" version="1" fragment="single">MYDNEEKQFEKFSENTFAKNVDRFNFEETLQEIEQNINKANFISIDTEMTGLSSGLSNNLELYDSMESRYEKIKDSATKFQVLQYGLGLFFFNSLTKRYEVQAYNFYTFQNFHKNLGNEFKSAKNLIEKRHCFLSQAGSISFLSEQNFDFNRCFSRGINFLNKTEVNLVKQEVLGKERCDSPLLIIEEEDVRFVNKATEEISNWLQNSNSKSLQIDAPSSYHRRLLHEQVKLKYNGYCATEGKEGCVIVKKLTKEEKKNSLNNDLKFEVTLRQLIGFSQVIDLVVKSKKPVVGHNLYLDLCHTLHHFLEDLPSNFSEFKILVSKYFPLIFDTKFICTDPAVMEFFSNSNLGEASAAVRKSPFLNPLIESPFGEEGELHDASYDAYITGYLFLKLFGKILKFGLDEDGSREVDYNLEAVKTYNGKLFLMKSDYDCLNLFGEDDIPDRSNVFHLYDSPQKLNYSDLNKKFKNFGKIYFRPEQNQNKIFENGSSCNSVAHEVENKYNCFFKLRDTTKINSFKKSFGLCENGDDTDRLRNDEGELVEFDFKIETYESYLNRSRELSGCGERPKKRKRNLSLVIEDDLISETSETGKNDNCTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWX9</accession>
    <name>A0AAD5TWX9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">trimethyllysine dioxygenase</fullName>
            <ecNumber evidence="5">1.14.11.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Epsilon-trimethyllysine 2-oxoglutarate dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">TML hydroxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">TML-alpha-ketoglutarate dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_007423</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:14181"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:58100"/>
            <dbReference type="ChEBI" id="CHEBI:141499"/>
            <dbReference type="EC" id="1.14.11.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; carnitine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.8" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000718">
        <property type="protein sequence ID" value="KAJ3213364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWX9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050353">
        <property type="term" value="F:trimethyllysine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045329">
        <property type="term" value="P:carnitine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2020.30:FF:000002">
        <property type="entry name" value="Putative gamma-butyrobetaine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF51">
        <property type="entry name" value="TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0124">Carnitine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="17">
        <location>
            <begin position="36"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="16">
        <location>
            <begin position="219"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3213364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="396" mass="46608" checksum="F0823245A1C391DD" modified="2024-05-29" version="1">MRNLDVPRHSICRSFTSTSKNVDLKKKIKIDSEKIENNLITLKFSDNFLANYQYFWLRDHCQCEICYHTVTKQRLLNTFKIPLDITPKTVGVHNDGVTIIWNNDNHESNYSIDWLRKHSYSPKLPLVMKQNTSIFDQKLIYWDSRFKIPSVSYQEVMETDEGVLKWLNNIRSTAEDLLKHPFILSCETNFDKNLLKKSLEYRLKKNDKKVEVVTKRKFWDFTADLSHEDTAYTNLALSAHTDTTYFTDPIGVQIFHLLRHDGNGGKSLYVDGFHCANILKKKFPMHYETLSTLKINGKIGNFNAFQNFSIFEHDKNNNDKLTMDNLVRIKFNNDDRDITDFNEADTEKFYLALREWMKIVYNENNELWINLKPGTVIAMNNWRVFHGRSSFDGIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXC0</accession>
    <name>A0AAD5TXC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">OTU1</name>
        <name evidence="8" type="ORF">HK099_000862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010001213">
        <property type="protein sequence ID" value="KAJ3205338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXC0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22745">
        <property type="entry name" value="OTU_OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048857">
        <property type="entry name" value="OTU1_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21403">
        <property type="entry name" value="OTU1_UBXL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="7">
        <location>
            <begin position="123"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3205338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="294" mass="33474" checksum="C97117E99BE530E5" modified="2024-05-29" version="1">MRLKANFNSTSFIIGEQLTLQSTLNELISDIKQKFNISASTLLEIKAGFPPKVIKSENENVILKDVNIVNGDQLFISEKPISNAINYNNNEKNMSLINNENFTTNKTNSTNADDCVPLEEGFLVVREMEDDNSCLFRSIGYVIEKNFEKKNLTRLRNIISEEIKKDPIEFNELVLGQPILKYCDWIKKETSWGGAIELKIFSEYFQTEINSIDVQTLRVDKFGEGKFGQRVFILYSGIHYDAIAFTPLKNVSADFDQTSFATPNGKVTVDTVLQSARKLGEIWKKKKKVIISFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXJ3</accession>
    <name>A0AAD5TXJ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006769</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the actin-binding proteins ADF family. Coactosin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000602">
        <property type="protein sequence ID" value="KAJ3214658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXJ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000018">
        <property type="entry name" value="Coactosin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF56">
        <property type="entry name" value="ADF-H DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3214658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="200" mass="21952" checksum="5B76FC9657F63CA9" modified="2024-05-29" version="1">MYAMINPLPTGKDLHVICVVLLIDAARLLLGYSDDKKDELNLVGSGSGGLEELKSHLKPDQANFGYLRVTIGNDELSQRAKFVLVSWCGSEVKVMRKAKLSVHISDVKNVLKAFAVEIAASDMDDLDSKKVDLLVKKAMGQIANWLILETEPGNGGLLVALEGNQNLFTYGEILQVYLLPEIKAARKNFGIDMVFGVYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXL5</accession>
    <name>A0AAD5TXL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007014</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000647">
        <property type="protein sequence ID" value="KAJ3214139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXL5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05288">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11385">
        <property type="entry name" value="RagC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001086">
        <property type="entry name" value="GTP-binding protein GTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039400">
        <property type="entry name" value="RagC/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF2">
        <property type="entry name" value="GH16429P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="10">
        <location>
            <begin position="18"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3214139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="665" mass="74618" checksum="8A5BBF53D89D0484" modified="2024-05-29" version="1">MPTLTNTKILFVKRPTGQLIPNETFRITKEEFDTNIPDGHLLIRSVYLSLDPAMRGWMNDARSYIEPVKINDVMRGAVVGEVILSKNSKFKKGDYVQGTLGWQKYAISNGKDVSIFSFPEGTTLLQSQGCLGMTGMTAYFGLLDIGKPKAGETVVISGCAGATGSIAAQIAKAVGCRVVGIAGSEEKCEWLKEIGCDEALNYKDKDFAKNLSKATPKFIDVYFDNVGGDILNLCLRRLAFKGRVVLCGAISQYNEKEPKGNFFLFIILNFLGPSAYMTLISMRAKMEGFIVFDYAKRYSEARKQILEWLNSGKIQQKETIVEGLENAPNSLLHLFEGKNIGKLLVKVSEEHEEDIVKMKNDIHDEVSLTSPLSASSFSQKSLNTPTALNSAKILLMGLRRSGKSSIQQVVFRKLNANDTLYMESTDIINKFEFNSFEEFQIWDFPGQVDLSENNENLEEIFLNCGALVYVIDAQDDYLEALHFLFSTITAAYKINPKISFEVLIHKVDGLSDDHKIETQRDIHQRMTEELEDYGLDVVRVSFYLTSIYDYSIYEAFSKIVQKLMTELPTLENLLNIFCSNSGIEKAFLFDVFSKIYIATDASPVDIQSYELCSDVIDVFLDISSIYDASEDPNDGIYGKKRHDAQSHSLIKLNNGMVLYSRAINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXU7</accession>
    <name>A0AAD5TXU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ferroxidase fet3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FET3_2</name>
        <name evidence="5" type="ORF">HK099_006432</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000553">
        <property type="protein sequence ID" value="KAJ3215304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXU7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042042739" evidence="3">
        <location>
            <begin position="17"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="23"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="92" mass="9979" checksum="A382D1CE54105EB0" modified="2024-05-29" version="1" fragment="single">MKYTFILLALLAVINAVTYNWEITYVNVNPAGTPRRAIGVNGVWPPPPLEVNLNDTLIVNVKNSLDVPTALHSHGLFQNGTSFFDGATGVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXY1</accession>
    <name>A0AAD5TXY1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000617">
        <property type="protein sequence ID" value="KAJ3214476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXY1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="702" mass="80164" checksum="D96FACB07B15E120" modified="2024-05-29" version="1">MTSLPNTSYMTHKYRQQIQNLSLSNQTSPTTTLENNLQHSPQTPIQSSTKTIHVAYNFRQTDRGELFLTFRKYPGFDLIGFYDRFCFVRFKNNESSLNAIINFLPPFGVTTYENANKFYEVPYPQPDDDHRLPCKILHITHLPANYTKIEVEKIFGLFEGFSEAHFYGKYGYAYFDTEQNASLARLTLRQETNLVVSFAKSAPKPTLTEASHLSNGQILVTTLNDNNTNNNQSNKSSNRQHNDNMDLNPKISIVGDHNKKISNLMLLQRDPNKLNVADSSTIQQQQPLPPQQQKQPGVVGAGTPKLNQERKTSVSPIPIPIKNNNNYFHHQQQQQFQTSTQQSQFQFNQSNVQQHHLQQQQQQQFLSNQQLYLQQQQQQQQQQQQQQQQQQQQQQQPFQQSKRNYFNSNSHSLKQSQSLVEQNFFQSFNQNQKEFKHSSSFDNQSPNSSTSTSSNFFENSPNSNAGANLLKFDRTPGAGRPGNIQNFLSLPPPPSTSNSFTQESLKNKDKVLDKNSAVDNLNKNFFAKPSTSLPIQAEFENLKLNSSVNARDIFLKKEKILLKEKDLIQDHNSKGGNSQVTNSSKEEQTEKYEKKNSNNNIDIFVKAKPVEINSNNRYQKNNIINTRDIWGNNNNGEMNANGFFISNPLDDLKNKSKSSSGADVNYNMNTTSTTNTTSTAATTNSKSIKVNNNNIWNPFTNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY36</accession>
    <name>A0AAD5TY36_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001571">
        <property type="protein sequence ID" value="KAJ3202436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY36"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019170">
        <property type="entry name" value="Meckelin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21274">
        <property type="entry name" value="MECKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21274:SF0">
        <property type="entry name" value="MECKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09773">
        <property type="entry name" value="Meckelin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="488" mass="55945" checksum="C5BB96A1C44B618E" modified="2024-05-29" version="1" fragment="single">TPYHQKISDILKSQKLNKLLSDLLKFEASRENRHLNAQDDKVFLFKEKINYKLAGAAGFPAHQDAPAFMQLGEPMHVSMMIAVDEATKENGCLEVVRGSHLSNILPQMEDGSIHEDWCKDKLWEPVTCKPGDCLIFGSYLAHRSGPNNSSKNRSAFYFTFNDQNSGDLRESYYNEKREKFPPMIDRIDGKDYSNDLRQSNGKLFPVPVRIQNFLQEGVYVNLQKSEISSTPMDNSIASALFTDFGDDRLTRRFFLVDTLSGVQDGKLMVLRVATKIKVWITKSPRADGQIYSPIVDIYYSERHAPELALNDNSLFSSLVFNFEVIYRMDQSYFWSIMLIIFVILSLVATFLAFYEAKKFSSFNLEPQDVNQCRIDIFFMDWEKSKGKVIHHLQHDASETTLNTSSVRDVPISIWRTIFVANQWNALQSFRRINVTFTLVLMFSLMYGIKLRYLATPQPDATNLSVDKTNPILLFSINTVIWGALCTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYP2</accession>
    <name>A0AAD5TYP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Asparaginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_008477</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000933">
        <property type="protein sequence ID" value="KAJ3209562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYP2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000040">
        <property type="entry name" value="Asparagine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1910.20">
        <property type="entry name" value="asparaginyl-tRNA synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048952">
        <property type="entry name" value="AsnRS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF16">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20917">
        <property type="entry name" value="AsnRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="201"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="55"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3209562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="501" mass="56982" checksum="F63900D4AF7CF858" modified="2024-05-29" version="1" fragment="single">MGTQYVCLISGNDEKGDGSESKPFKTALKAIEVLQGSSEIKIRKELDSPFDDIAKAQLKKVKKLYEEKLKKLQKLSQNSEKNLQEEKKKEEEDLKRLENAKSIVLVQDSSLPKAKNCHTYDAITLTLESTVKVYGVINELPEGKSAPDGHELLVDYWEIIGKAPGGDEAITNKVTDDAVNKEQLYDQRHLVLRGETVSNVLKVRSITVKAFRDFFSERHITEVTPPLMVQTSVEGGSTLFAFDYYGDTAYLTQSSQLYLETCLPALGDVFCITESFRAEKSSTRRHLSEFTHCEAEFSFIDFNDLLNFMEDMVVSVVEKVFADPEGKKLMSVLHPEFVLPKKPFKRMDYGDAIKWLKENNVTKDDGSFYEFGEDIPEAPERKMTDTIGVPILLCRFPAEIKSFYMKKDKKDQRLTESVDLLMPNVGEIVGGSMRISDLSELMAGYKREGIEPSPYYWFTDQRKYGTAVSGGFGLGVERFLAWLMNRYTVKDVCLYPRFIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYT3</accession>
    <name>A0AAD5TYT3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000921">
        <property type="protein sequence ID" value="KAJ3209826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYT3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042118645" description="DOMON domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="18632" checksum="56F921B9F2B9BCB7" modified="2024-05-29" version="1" fragment="single">MQLLVLFLVLKCILSNGTTSETVLKSTSPTDLLLFSNSFKLTSLSNSGWFTFSWNLLNPNTDNETLHMYISLTDVDMVHGWASIGFGQDMRNSEFIVVHQLNDGAFVNEHRGTQYEYGPPLVIQQPFLINVINCGYFNKTLFAEISRPTKGDAFHIPIDTNAQYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ15</accession>
    <name>A0AAD5TZ15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000438">
        <property type="protein sequence ID" value="KAJ3217216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ15"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="96" mass="11604" checksum="3944AE8C70511666" modified="2024-05-29" version="1">MAFCSLPWKSAEVSDQRFKYYIDHFKHYWPMDRLKPILRTLIYNILNPNPVERFTIKNIIEDGWFKEIVICHDESLSEEENAKIRINHNHNCVKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ47</accession>
    <name>A0AAD5TZ47_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000868">
        <property type="protein sequence ID" value="KAJ3210878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ47"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024624">
        <property type="entry name" value="Pyridox_Oxase_Alr4036_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243">
        <property type="entry name" value="AGL049CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28243:SF1">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE ALR4036 FAMILY FMN-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12766">
        <property type="entry name" value="Pyridox_oxase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding" evidence="2">
        <location>
            <begin position="20"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3210878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="280" mass="31607" checksum="F8A0DCBC0993A3B7" modified="2024-05-29" version="1">MTLIQSLNNNPPSHLHINHPPWKPHFQNALNSNNKFSTNVIVTAVNSQTGKPVSKNLTFTGFHSGLHTKKNPSAPGNPNVVGKIKLEGLMQFAVDTRGIKDWFGIPKHNDNERFVDVSWFFGQTQQQFRCSGKVFLVATPNSFDPPSSIPPWAPKDIDWEEERKYLWKTLPQKRKFSNVFPEDELNKNNGKLFNLGGITIPINSQHSETLKSSSLTATDDSLEEIDVPDNFGLLLVDIDYVDEMSLEEPTSKTVYQVKVPLRTYGRVSGCEWEEKVEVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZP8</accession>
    <name>A0AAD5TZP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001023">
        <property type="protein sequence ID" value="KAJ3207906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZP8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="100" mass="11589" checksum="D646E51977A70490" modified="2024-05-29" version="1" fragment="single">MSLKVDTNTLPTFLQKEKVKFLRCCGVDVEKQLVLNFVYMILNISSSVGIVMSNKWIFHHHKFEFGTTLTVVHFFVTFVMLEFCSKLGLFKKTVLPLKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U002</accession>
    <name>A0AAD5U002_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Intraflagellar transport protein 80</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IFT80</name>
        <name evidence="7" type="ORF">HK099_006381</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000545">
        <property type="protein sequence ID" value="KAJ3215413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U002"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000007">
        <property type="entry name" value="Intraflagellar transport 80 homolog (Chlamydomonas)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000463">
        <property type="entry name" value="intraflagellar transport protein 80 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056456">
        <property type="entry name" value="Beta-prop_IFT80_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056157">
        <property type="entry name" value="TPR_IFT80_172_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24098">
        <property type="entry name" value="OUTER SEGMENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24098:SF0">
        <property type="entry name" value="OUTER SEGMENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23335">
        <property type="entry name" value="Beta-prop_IFT80_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23387">
        <property type="entry name" value="TPR_IFT80_172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="194"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="IFT80 second beta-propeller" evidence="5">
        <location>
            <begin position="311"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="IFT80/172/WDR35 TPR" evidence="6">
        <location>
            <begin position="634"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="785" mass="88197" checksum="CC412D70F2F42232" modified="2024-05-29" version="1">MSKLSKIKINSYIKHTECTTSIGWSGNSELYSVGDDQKILKWSSDGELLAPFQTSLFDKSGDPNSPSLFLTELHWFPATPGKSQTNSEIFVVGGSDGKFYLLARSGRVEKKVEAHKGAILALKWSYEGSALLTAGEDGQIKIWSRAGMLRSCLTQSAFPVYSAVWSPENDQILYSSGKNLVIKPIQPSTKPTQWKAHEGIVLKVDWNLANNLIVSGGEDRRYKVWDTYGRQLYSSILHDQPITSVAWNPSGDMFAIGSFNCLRICDKLGWSYALTEPDSGSIFNISWTPDGTQLACAGGNGAVVMGHLINRRLEWKNYEVTILDDKKVLVYDISIAATETLEFRDRIIKASIAFNHLIVCTPSQCYIYSDKNWNTPAITDLNPGGRVVCIKQCAEYFVIVDTIVGMHVYTYEGRPVSQIKYLGLRPEYVTQHSISISGDTLAIKDRTDEKSIYLFDVTTGTPLASVSGGGPFRHSIEVMELALNQSSLIGATSGINGRQLVIVDKNRDMWITGLIKVNFKKLGTMVDTFSWNDEIDIIAAMVDGKFTVWYYPNAVFIDQDIAHLTKIERDGSTFGRDAQFVSFSGTQCTLRKSDGSLVTVSFISPFPSLLHEQTKKKQWEDAIRLCRYAKMNELWACLAVMAVAGQDLNTAEVAYASIQELAKVQYICYIRDIPSAEARTAELALLRRQPKEAENILISANLIYRALKMWMNLYQWDRALELAVKFKSHVDTVLYCRKKYLKSMDKTEFNKRFLQFNNDPGFEIVEEKILEKISFEEGKERNGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U028</accession>
    <name>A0AAD5U028_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000536">
        <property type="protein sequence ID" value="KAJ3215542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U028"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="313" mass="36494" checksum="B679C2EC6211708C" modified="2024-05-29" version="1">MWGQYNRYHETHLQNVSGKYRDGSSNSAKKFFINGNNIKYQPKTKAQNFKTSTSAGNINQDNFSNSKKLYDAEVDDSTSVFSDTSNESSIKSDVYQSTVELSNCLLEKAELEVYDYSKILSTESVVNSRNLFNQTIDMVVRSHLNYAKNFPEDVLEDMRERAVKNKVFNPVLGLKSYRQHQDFFSETSRFASLDGMIPFLNPKEQLLVLKVKEKILLVERWKNLWEEVRPPKQNWYESKGMDFAYESKKCKNLASNREYQILAADSRKKEIDDMLFDDTVHARSDTAVHILIDYPIKGLSEKRKERRKNFYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U046</accession>
    <name>A0AAD5U046_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000359">
        <property type="protein sequence ID" value="KAJ3218941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U046"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="330"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="498" mass="55721" checksum="46B4B3B3CE2009D3" modified="2024-05-29" version="1">MNKDTTATESSSDQEVINDNTNAEVNDQHAISKTASSTSVAKVDAEIFNQNIEVQAESDENSFPIVAAVDGAEAGEHVVDNNDTVDNEGSCSTENSGFNEINALSKELENTIIIGSETEKNSFDTTETNESSSFFKTLSANSIKEAAIGEMENAMEKPDGDKTADVARENLQSKIEDADKVNEDTVDCSNSKPEAPGSSVRHSKRSSVKNSTRGSVTNSNCSSVVFSNRSSINKPNINFENELKVEANESTLSEIPDNLENSKDYTDETILDENVEKQQNQDKEVLEIDDQHNYNEDFESTSNENISVQEECSEKSDQYSLTEISKDGKITNITQILEEKENYIKQMEEKLLAATFNIEDIRVNSAKETGELRKIIKELKENEEKIEKDSEAAIKLKEEVKQFKEIMKSQKCEISKLKEEKVTKNGARKLNSAKMVESKNQILEIHEDLKVLNQNLKVKNLEVKLQLKNSEKILNNLKLSNREFLSPREKRMANSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U064</accession>
    <name>A0AAD5U064_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000695">
        <property type="protein sequence ID" value="KAJ3213599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U064"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1450">
        <property type="entry name" value="LAG1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036358">
        <property type="entry name" value="BTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040159">
        <property type="entry name" value="CLS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015351">
        <property type="entry name" value="RBP-J/Cbf11/Cbf12_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037095">
        <property type="entry name" value="RBP-J/Cbf11_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038007">
        <property type="entry name" value="RBP-Jkappa_IPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10665">
        <property type="entry name" value="RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09271">
        <property type="entry name" value="LAG1-DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20144">
        <property type="entry name" value="TIG_SUH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110217">
        <property type="entry name" value="DNA-binding protein LAG-1 (CSL)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RBP-J/Cbf11/Cbf12 DNA binding" evidence="2">
        <location>
            <begin position="309"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="RBP-Jkappa IPT" evidence="3">
        <location>
            <begin position="889"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="987" mass="112108" checksum="6EDB7220C22294E7" modified="2024-05-29" version="1">MDFNDSNIMLFPYVADIENDQSGGIFKKNKTDFFSDLLSKSCGQSQKSSDLTIKEKEICRSNYFSNLFNKFCDQNRLPIDFGTEYEKIFGSLPKFNQNKASFHERGVEYISTKCNNIESAFPETQQSYNMFNYLKNTSEGKIMSPDEFLKIDEEMNEVLAQSFSQHSFPVSASSSCLSITLPSSSPFCSTPSCSSPNCCLSIFSITSCSSPTCSSLSCPSPICSSASFAPSTPTFAPAFKPNTSTTAGESINYKSERKKKRSTPFTSLTSEKSVIPQNFSGEVGLKSLIPIFNEIVEEYLRDTNLEKTVILSYPKVVQKSYTNDCKAERRFISPPPLCIVTKPQRNNRKRDQIGNKIEVIIQTSPIKVVHDNLETEPIFKSSETFENLQKKRKLTEKKETATETDFKSQNEFSSKKNNMLEAWYVGEMDHLYKRMDGLSNTSSVNDQVSYAVNGVSRFPRPVAQSVFKTLHTTEINSFSLHIKLFQDEIQFFKLLTDPIKVLSKPPADLRAVKHEIAIFSGKTVCLSNRSQSLKTKYLSTTNDGRNLSMTDADWEHFRIFKYNKRILPDINIPFKFNQSDIPLSIASLASRSHLDGLRSWGINELNTLKLDTLKESEINSDVIFQQPSILSDARVEGDFKNISLSNYMDICGVGPAKPSQSDDTTILQSTSPEDSKSSTFKVPDEDLSVHLSTDVEEQDPIFFGDVVYLQSVSSGLRSKPFILRKIVKSEKKKFALVEPLENRLVPGLQRPLCQLQKLAFESLQKPGFYLTNVLNNIMLFQTERSIHKLNKKDIDRHTKKRPKTSDSIKEAYFKDGINEFGIWTIVETEKAEVTFFNSQDLKEEFECAGGKTVLHKKSKTQLKNAENAILLQKSNESEEKNLNLLKNFPILKKIIKKGLNEIYLVGNFFENVDADLKFWIYIGNYPCENLVFLNKNVIICELPIFQLRNGRNFTNCQHNNENVLNMPILFLREDGILFRTGHYHSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0W7</accession>
    <name>A0AAD5U0W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000282">
        <property type="protein sequence ID" value="KAJ3220666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0W7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="66" mass="7799" checksum="EBE22EF056EDFE65" modified="2024-05-29" version="1">MVVIEDQRGKKPDNSPHKIKRNIMKPGHRKEAKENLAIKDEILRFEEEEEEKNLLKQEESNASNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1M8</accession>
    <name>A0AAD5U1M8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Saccharopine dehydrogenase (NAD(+), L-glutamate-forming)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_003437</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 1/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000225">
        <property type="protein sequence ID" value="KAJ3221525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1M8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004753">
        <property type="term" value="F:saccharopine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12189">
        <property type="entry name" value="LKR_SDH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000087">
        <property type="entry name" value="alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000072">
        <property type="entry name" value="Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1870.10">
        <property type="entry name" value="Domain 3, Saccharopine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="9">
        <location>
            <begin position="5"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="8">
        <location>
            <begin position="183"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="918" mass="103598" checksum="AD1E08DF7D9C520B" modified="2024-05-29" version="1">MLSLGIRREGKNRWERRVPLSPDAVKEIISTLNCKVYIQPSEKRIFEDYKYEHAGAVLQDDLSKADVIIGVKEVPEDELIPNKTYLYFSHTHKGQSYNMTSLRAILEKKIQLLDYELLTNESNQRLVYFSVYAGYTGTIDILHGLGQRLLVKGFGTPFLNVGMSYQYSSLEEAKLDITKVGKIIKENGLPKTLGPLVFTFTGSDGNVCKGALEIFQCLPHEFVSIDVVKNMIETNNFKSDRVYGVKLMVEDFLYKKDSNSSKDIDRYHYFGNSDEYNSNFAEKFAPFTSVLINGILWNSKSPRLLTNQQTKELADANNLRLISISDISCDPYGSLEFMSKVTTIDEPFFYYNPKTQKNSSDITSEGIQILSVDNLPTELPLESSWHFSSTLLPWIKELLKGNLENTFTLRNARLTTSDGKLVERFHHLYDSLEKFGKTKKVLLLGAGYVAEPLVDYLLRNPNLKITIANRTIEKAKLLASKKNKNVSFASLNLDDKESFSKLVAEHDCVVSFVTANHHPVVAEQCIKHKKNMLTSSYISPAMAALDSKAKEAGITILNELGLDPGIDHLTAMRFFENVPKGGKLISFVSWCGGLPAPENSDNPLGYKFSWSPRGKNYSDCIILIFHEGVLLAGLNNALYKWDNQIYKVPGEQLFKTSRKVQINKGLALEGLPNRDSLSYIEKYKLGHIDELKTMFRGTLRYVGYSELMAGFNDLGFFSVKENPSINGMTWPDLLKKILNLTNLENLQKTLYIKLKEINSSINLVQKGFEVSEELALRIYETIKWLKMLETSTIVSISAGTPPSVLDAFCALLQLNMLYEKNEKDAVYMHHEFEVEYAEGKIETHTSTLVAYGEVGGYSAMAKTVGLPAAMGVEMLLNGELNHRKGVIAPMTRQVKSDIYEPLIKKLEEEGIKFVEKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U272</accession>
    <name>A0AAD5U272_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein dennd6a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DENND6A</name>
        <name evidence="4" type="ORF">HK099_002753</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DENND6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000194">
        <property type="protein sequence ID" value="KAJ3222052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U272"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024224">
        <property type="entry name" value="DENND6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13677">
        <property type="entry name" value="LD41638P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13677:SF0">
        <property type="entry name" value="LD41638P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="212"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="642"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1070" mass="120651" checksum="9575B2C864C5D197" modified="2024-05-29" version="1">MDLSDLNNINKLKDVDVRCKSLDLDRNRSVHSMSSHNIQSQNKNFIVQSNYTTIPLNDIKVTPRKKTIVRSDSAAHISDNLTFRSSITSNFKSEVPNSLLNSIVSDASDCSLHSKMHKTNSSPSLVLQDSPRETNLAELDKYSCKSTIPEATKNNKNQSLIADLQLNTNDLQPKPIEKDTSMLSNQYNLESKTEKNFVGNEKKLSAFWQWALCFCVVNFDLEVGQALECVYPKVYLTDTEQKNISFSAFPDSNSSAHVGDSNFSFRMRNGPYSNYLYKQSQPEMNTSPQTSPKFTFARSESAAQPILFESKEKSCTIPIDSDGYCYGYVFFRQQSNSEIRRGFFQKSLVILSPHPWRGLFLLIVKLLGAKVMDCLIADRNSYSKKHSECSSEQNLGGSCLPGTTSYELLVKACNEIAAWPSPPSQASPYPGYSPIAMQLPFFNVKKSFLFPPSPSFPLFHEIPKSRNPSNSVVNPLKKNVANFSTVKEHNSVQNNFSLSSTPPLRENSPDIGKVVKGSKISLLPSTLCCPSRLYELFARSLEIMWLCWELMVIGEPILVIADTPKGASDAVLAFVELIKPIPFGGDFRPYFTIQDSDFKNIANRNRPAPSSTILGVTNPVFVKLLEHWPHVIRVTKVINRSSNTRNDDPKINSLRPSSPPSSMKSLKQALRGASPTPAEMKPNQVINPAEPSVIQGLQRLTFINTLAPKISFILAPQLNNMLRHHFVELTDRFLQPLNRYFEGLVVGNQMSMTLTTLRGRPEIRPFKQETFLKSIETSTPALSVSLKRSASELYRAFLMSPNFASWLQQKTSEVFREWRRRYLEVICEANILEWARHDTPDPRSEVECVDLLLRIRDELNRYFPYYTLNGDLIEYSNPSTPFNSNDQQWIIRSPSPPRPVPAAIIDRELEQTQLNRPNNFSNAALMSNSGNQSAVNFSASVVNISPKPFSPVQSCFENKHFSNSTSLTCNIENSNKHLNFLRNKLKELKAIQHLNETRKLNNIENTSSSLLNSNKKNILADSSIKSKEGSMGIFIPTVKQYESLLIQFEKLLNLLPQDLRTSVLGHEIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2L0</accession>
    <name>A0AAD5U2L0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002773</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000195">
        <property type="protein sequence ID" value="KAJ3222035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2L0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="5">
        <location>
            <begin position="77"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Velvet" evidence="5">
        <location>
            <begin position="440"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="605" mass="69138" checksum="AAE0304EFC5D24DA" modified="2024-05-29" version="1">MQSRNEFEDDYHNNSFCNQDYLNSEITNNSYCTLTCLDKILLDSNEVIKSSNGFLKDQNEELVESTKRKRTEGSYSNKEKEYTVIWRQKPVHARMSGNGAKERRTIDPPPILELMEYVNGNLMPIIEENCFTHMRAALYSPDGTISLEELQRGMLKNKATLVESSAQPNFDFPEKSAHEIHEISNQRGDLTASIDSTTDLSIETIPSKIKEIKKNRKYKIIWRQRPIHGRMSGNVGTERRTIPIIELLELKENGEFMPITEENIFTSMRASLYDAEGKTCLNNAQTNVSKDFPNILGDTVECSVILYDEFDRLGTFFVFKDLSVRSPGNYTIKFTLYDLESDVAPYGQLASKKSLINVLLAPITIYKPKDFPGTLNSSALTKAFKKQDQFFSNNDRHCVSTAQQHPQYQSNANNASEINEQNSVLVQSSRRKMNEGLIPERKKKYAVIWRQKPVHARMSGNGAKERRTIDPPPILELLELNLFSSVQDNCFTHMRAALYTADGKKSLESLPRERSKNQAILVGDLIEYSRVLFDDLRRTGTFFQKRSDTHRGQLASKKPFQFQIFSPPVKVLSPKDFPGMLESSNISRVFNNQGLKLTIKNKENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2M3</accession>
    <name>A0AAD5U2M3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Homing endonuclease LAGLIDADG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000343">
        <property type="protein sequence ID" value="KAJ3219328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2M3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051289">
        <property type="entry name" value="LAGLIDADG_Endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181">
        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181:SF2">
        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00961">
        <property type="entry name" value="LAGLIDADG_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="1">
        <location>
            <begin position="39"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="1">
        <location>
            <begin position="103"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="174" mass="20169" checksum="9039177DFF90F44C" modified="2024-05-29" version="1">MNWLVPVMVGAPDGKYHNIVTSNSVSNTHKYTHLCGHYIAGLWEGDGHIWISKTSKSTPHFCITFHEKEYPIVFKLKQILGGNIRHKRKEHAYVSDLINNHWLAGFIDADGSFDASIRKIKDNSRIIIRFRLEQRMFDSKTSIPYEPILRQISKEFKLNLGQSIHADAYLKKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2M6</accession>
    <name>A0AAD5U2M6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000408">
        <property type="protein sequence ID" value="KAJ3217836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2M6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="537" mass="62614" checksum="130C9D4207BB86BB" modified="2024-05-29" version="1">MLTLTLNHALYYKYSTLNPQQFSVKHYLFHPKLILNKVVTLFWCVKRVKPKKISVLQMSNLNFPAYGLRTPLTKGFPTNGKKIILRVLLISIAGKARQTTAPKRNDNRNSAAPNTRVEDERSPQNDQMDQRQNRQNVHAQSHNGPSAMDLSSQTAPLNDSIKNLKYKYIELQETHKKESKKLEEQLAQLKTEFNFQTITLQNVEKERQELIEANKQIKEHNTAEKDKIYGEALSFRKKLQTSQSDLSRMELQYQRINTERQKFQTENGSLKEESQIEDVHATYSTFDLDAHKARIGELQLVIKELRSQVQIAETRQQQEEHLRMRAMEDCSELVRANVGLKTELEDVQRRLRKVLIDEFEQREEKLRHKQEKIKDVEIAREEVSRLKDDLTMLKISTDAKDNKIYELLSKNKSVEALDTQRVLEDRIIDLENRIRIGEGEVIQLGQDKSLLIDDVAELRNSTEINSNKVKTLVREKQELQVELAKYQREMSARKEFSSMLQNLEASGENYLGLMRNMKCFIKGDTEIDNQNTESSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2T7</accession>
    <name>A0AAD5U2T7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphodiesterase</fullName>
            <ecNumber evidence="5">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PDE9A_1</name>
        <name evidence="8" type="ORF">HK099_002586</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000187">
        <property type="protein sequence ID" value="KAJ3222187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2T7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="418"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3222187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="515" mass="58933" checksum="7F5878EC883D2617" modified="2024-05-29" version="1">MSFTVKQRSIINQTMNQFLNGSLTGALGMHFNVWDWNLYQLYGIILATFVKLGLVKDDLTLQMLLDFVIDVKKGYPDNPYHSFLHAVDVEYMMYYILIDLNVKDKVGFSTLECTSLLISALTHDIKHPGKNNLFQVNAQTELAKKYCNESVLEAYSCDILDELLSKHKFLNRLDFGILPDLVDQSGNKLDKICFLKETMREAIINTDMCYHFLLLEQLNIFDNNSSTCNNNNDTDDSTISSLHKQIDSNNSCIKEKKLVKCNNKLDASTKSKFLAEKNCIIIPKKLRERRKMVNILLHAADISNAARPFKICKKWSDMIVEEFFLQGECELRLNLPVSPSMDSTKTNQIKIAIQFEDLIARPFFEALSSVLIPLECYLETLISNRVEWLELLHFKKDKEKNDVNKHVDTEKFDFVDQNLPSSSNNANNSGNKSSEGFNLGRRLSTAAGTIEIPANNIFGQRSPNVRYKRHSFSHSSETSANRLNFSNTANILEDYHGVRNSRIVDEDEVMEEVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U384</accession>
    <name>A0AAD5U384_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="7">4.2.1.93</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002003</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6S)-NADHX + ATP = ADP + phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19017"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(6S)-NADPHX + ATP = ADP + phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32231"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.93" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000163">
        <property type="protein sequence ID" value="KAJ3222693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U384"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047453">
        <property type="term" value="F:ATP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110051">
        <property type="term" value="P:metabolite repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592:SF0">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF C-terminal" evidence="9">
        <location>
            <begin position="353"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="43"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="118"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="521"/>
            <end position="527"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="556"/>
            <end position="560"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="646" mass="72195" checksum="3437E1DB1FE2194E" modified="2024-05-29" version="1">MENSAPFNAEAQNNDTMNNITDNIDPVEFKNSKRTRARFEKVGDIEVEKSETGNDQIAIPPEGSVSQKRKSDSGNSTFCSDTNVENNTEDQDDQDDEQMENENGNIDETVQLIPLQNFQQQAASRKRGRPVGWRKQQNGDHPSPSQSPSSQKRILPLQVLQNNAEQNDQKRGRGRPRKSEFNSIEGTPVQTDRVWSWEEDDILLRYLEQDSNYDTWKLSKRDDSKLYKKSKDLAIEISLLLNGLNSWEISGDDYLKRIHEFEKSLKKGWNFLLSQGKFEDSLEVKLRDPKIKEKLDIKCPLFERLYALMGSLQSESPVNTTLNDNLNYSPVKLELGTTDYIQSLSTESAQNILDIQCQHIIPRLTEDSVKGESGRICVIGGSESYTGAPFLSAISALRLGADICHIICEKSAAMPIKSYSPEIIVHPLLRDSDSIGCEEGKIDGQIDAVYSKIAPLLKRIDCLVIGPGLGRDHVTLKLVAKIIIEAKSMDLPMIIDADGLIIIQNDPDIIKGYANAILTPNVREYERLLNALIPESDHNKPEELSKILGNITVVRKGSADCITLGSDVCKVLNGSPRRCGGQGDILSGVLGVFFCWAKLQEKKKTEENETLVSDTPIQILAAYAGCLIVRKCSLSAYEEVYFFSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3M5</accession>
    <name>A0AAD5U3M5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytoplasmic FMR1-interacting protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CYFIP2</name>
        <name evidence="5" type="ORF">HK099_003148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000210">
        <property type="protein sequence ID" value="KAJ3221758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12418">
        <property type="entry name" value="RRM_Aly_REF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009828">
        <property type="entry name" value="CYRIA/CYRIB_Rac1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008081">
        <property type="entry name" value="Cytoplasmic_FMR1-int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12195">
        <property type="entry name" value="CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07159">
        <property type="entry name" value="CYRIA-B_Rac1-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05994">
        <property type="entry name" value="FragX_IP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008153">
        <property type="entry name" value="FMR1_interacting"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01698">
        <property type="entry name" value="CYTOFMRPINTP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="1190"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1143"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1271"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1151"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1278"/>
            <end position="1294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1343" mass="152490" checksum="8307F1BB70EF9520" modified="2024-05-29" version="1">MDSSSIIYLNFSDSQIYDADQFYSDPGKSDFKPYKYFLKELGHIATLNDLLSDGKNLVSRLYSYRSCIRGIPQSNAQNNESKEELALQIFEVMKPEISKMKDFMIFRDHAVQCISDVLTSIIPDIKEKDVFSSTEFLLTLATVLDLFVVLDAMKNIKGSMNNDLSIYRRNATQLPRKLAEDDAAQIHKLIIFLGSQDQFSLELKKALAAIPQSDDVLVEVVNACADCLENKRYILSEKKHAYLKAVAFGLYLLDGDIDEKDINKKKKIKLDRLGKLMKSTPIVPLYADSPISLSHIFSKAPHIGQGKWDLTEIEDKGSLQKSYSLSTYSEEFRAIYVEYVANFTQTTICLEAKYLNCASYSNDDSYLIYQLILEGVKFLANCTTKSAFKYANPISIESNLPMLENAIPYELAVKYNYSLEDKRALIEFLSIIKNLSDLILNLDAKVYEALNSYMYREIQDFAQVNISEFICHATKKKRGIVRVAQEISSDIFLEEKLSNSTTSATKKKFTSELKQRKSPFSLTQLHFLKTYLDYGFSDKSKGMKGGLMKEKDFKDYQVAEVQKFFDFCLYFPCMMDLKGAVEKCVDVSDLWYKEFYLEISKQIQFPISMSLPWILAEYCLDSFNPEMFSNIFVIFDIYNDVAKSTMYNLNSQYIYDEVVAEVNLCFDVLIFKISQRIFSHFKKHASFKLLSADQIEELKNSSDVSKENMLSCFDVILKKKSFDLLGRSINVSEVISQMMNQYIRKSIDIAITRFEGSSLNNIMELHTLLKSTKMTHEMLSELLTLDSFADILAEVDERLALHSNGGRIAQHIIQEFIDDFIPNSAFNSTTNRCAVEFVEPLIRPAQIKFPPMYSFGSKSLTVAFHAQHQISETLSDYIYAIQKGTPTTLKLPIFEYGAAGAFEYFNAHFKPLIHYKDLKSEVLQTFREIGNSILVVRALQNVANMDCSYKKVRTDSLFNNTSSLSSFMSLKQKYLPDNDLKHLQKDNTLLNQFLKKLKTTLNELNKIWLNPPQLPNSAESENSKNPGSLVDNPRAFYKTWSALQFAFCYTGSDGCVTNRCTILHCLDQVKLFNTFDYNNHVISVHKAEKKSTNVLNQPVVSMQNPQINSSTNAEFNQFLEVAFFIKDQNEEILDFLEKQDPLNPTSLNKSKSARRGGRGGNHGRSRNSAPYQRPQRDNRPPLTTASSGPTKILVSNLGFHVTSEDAKELFSQIGAVKQVILNFNEQGRSTGTATVIYQNGKDAARAVSEYHNRTLDGRAMKIELLVNPDSVASLGRDNSSRPRRDDSRTGEKRGGRGGFRGGRFRRGGSFGGDRKAKPTKTAGELDAEMESYMKDEEMVDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U401</accession>
    <name>A0AAD5U401_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U401"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="26"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="121" mass="13653" checksum="138118A6ED1B4F24" modified="2024-05-29" version="1">MFRRLVTPTIRLQSRHFQTSLKSFEKTLFVRNLAWSVTDNDLNSLFSQQGQVLSARVISDRETGRSRGFGFVEMDDEAALKAVKELNGYELSGRPIAVTESDPNAKRGGFGNNQTRGGERW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U406</accession>
    <name>A0AAD5U406_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000254">
        <property type="protein sequence ID" value="KAJ3221067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U406"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="414" mass="47641" checksum="040D2D282E826BF7" modified="2024-05-29" version="1">MLIKLRETKSDIMDSMEPRDFIPPSSYDVLLSDVKHNDLIGPIAERLGIVYLKEVATRTDSSTKGILYGKNAKPMVNLTIASTKHKRFINVIFLVDTGSPYLYICEKAMNALGFSDHCPETFDITFRDMTFEAVVSPLKQPNGEDGHYKDINLIGASFLSKVRAKFIVDYKINEVKYIDQIALYQASKIFTNIAVNIQEHFVPKIKKFISNLIIQNQESLLPEKMLKKDWIKVLQARSRLVQKIILENIMDISEYELTILNLLRSILPETIEKNSVFMIHIRFDTNILIKVVLGLGGKITKGTLNVEDNLEDIWNKLFNLKKKPFKPRNGKVFSGSIETDGVSITGLEEQNECLPKQNVYGKNGLRNQNIPIPSRKLLDPIAFRIYLKDYLYRFTQLELHYKKLIFRNNFIAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U467</accession>
    <name>A0AAD5U467_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytosol aminopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002454</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000181">
        <property type="protein sequence ID" value="KAJ3222304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U467"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF23">
        <property type="entry name" value="CYTOSOL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="235" mass="24897" checksum="6413810740895A36" modified="2024-05-29" version="1">MALMKGDMGGAAVVLATMSALEKLDLPINVVASIPLTENMPSGSATKPGDVVTAMNGKTIEIDNTDAEAFVGRLILADAIYYTCITHKPKFLIEFSTLTGAMQVALGNVFAGVFTNSAELYQLLEKSGKESGDEFWKMPLDLKYLKAIKSNVADLKNVGDGNGAGSSTAAIFLSEFVPEKDGVEGVDKLSNKITEFAHVDIAGVMHNKGTVGYLGSGMTGRPTRSILELLCNLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4B2</accession>
    <name>A0AAD5U4B2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000262">
        <property type="protein sequence ID" value="KAJ3220934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4B2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="758" mass="86975" checksum="6B1BD7CD4B1DAF21" modified="2024-05-29" version="1">MIVDNDDTCLFCGLSKSGQFIGRRQGADEARVLIKCSCVSDDEVSKMIYDSEEFAYSVTSVSDPLAEELMIRNNSDSDRLQDRTFDMSSHTLYNEIEITLSPSLSSICFNRIEDYAEMIIFEAGHPGTNINGDLMLSSNVRFRIAAHTTHNGENSTNSQLNSFSHKSVTCNVKNVVSKFSCAPDITYKSSYEFDVIDWKPFLDNHLCKQSYSIMFIERICIIGDWLCRARKYSPDGVYSCEFEYIKSSKPSDEDVLCILDIIHSRFIHETNYGKYLRQEYIDILRHSARPTKDIKHIPGSKNSYRIKVDGEYAWVFDAGSIWYICRNDPKLTVVGYIMKQFISVFKALHTVIRVEQMVDGTLVLIDVLCLNGKVRDITRRYDDATTALKNGAIFPPNMIIRHEYNTMEEAQRARLTSDIPSDGIIIIEKNTSITYRIKNPTIDLLCTGKNLVTINENKRMSKVMDSLEGMQKNVIYECNIELCDNDKLKIIKAMPRYDKVVPNRPQVLKDIISVLKSDNMIDYTLIDRVSNYSFFVRKYMYSWANNRMRDNKLIIDVGSGRIQSISCIKENPNYSYLLCDPKLRIPNNIDSSKWLDATNYDDKSKLNLLERLHKGKDKMAYYRGSIESFFTSYNILSFVIDNRCMLIYCFSLSYMITFFNDMASRGAKQIGSCYIYDNIKEDSTLVDIGGIRLQAEDESRKNAIATFGNKVEYKEPLINSNDIRAREVDLAVNLPLTISDIEHDVRMVVSNIIVAKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4D8</accession>
    <name>A0AAD5U4D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphoglycerate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4D8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047545">
        <property type="term" value="F:(S)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12176">
        <property type="entry name" value="PGDH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000041">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050418">
        <property type="entry name" value="D-iso_2-hydroxyacid_DH_PdxB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008759">
        <property type="entry name" value="PRK11790.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="6">
        <location>
            <begin position="12"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="7">
        <location>
            <begin position="116"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3222465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="44693" checksum="36E6548D7B79DED7" modified="2024-05-29" version="1">MPSPTTSSPTKILLLEGVSLNALNSLTKQGFEVEYHKKALPKDILLQKIPNFHAIGIRSKTQITREILDAATNLQTIGCFCIGTNQVDLDAATQKGIVVFNSPFSNSRSVAELVLGEIIALSRQLGDRNSELHNGIWNKVSNNSKEIRGKTLGIVGYGHIGTQLSVLADAMGMKVNFYDSLSLMPLGTAKPLASLQELLMQSDYITLHVPETPETKNMISEKELSLMKKGSILINASRGSVVDIPALAKFLKNGHLAGCAVDVYPHEPFANGPNFHTELQGCPNTILTPHIGGSTEEAQFSIGVEVSNALSKFLTSGCSMGAVNLPEIDLKKPVGKNTVRIVNFHNNVPGVLKQINKILSDFNIEKQTLDSKGPVSYLMADLSLEDLREEELSQLHSDLNSINENILTRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4T7</accession>
    <name>A0AAD5U4T7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008625</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fmt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000097">
        <property type="protein sequence ID" value="KAJ3224302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4T7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138:SF5">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="FMT C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="5">
        <location>
            <begin position="59"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl transferase C-terminal" evidence="6">
        <location>
            <begin position="203"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="319" mass="36503" checksum="35B9A302CBB244F7" modified="2024-05-29" version="1">MLKNQILKKYNILFFGSDEFSIITLKRLLNSDIVQNLQVVTTKSVPLFNFSKTFLHLHIPPQHTLKSWEAPKLNGQDFDLAVVVSFGYFLPPNLINKFSVGALNVHPSLLPKYRGAAPIQHQILNDEKISGVSIIELDKKKFDAGKILKQSSLKVCNFPFYKVLHDELAILGGNDLVETIKNIDSFKKQAIVQDESLVTQAPKILKEMGRIDFNCMNNYEIFKLHRAIGFKIPLYAQFRKKRIQLFDLKLATLNFSTVDNFSAGSLLFDKQQKKLFVKCFHGWLEILKLKVQDKKLLSADDFHNGYTITESDHLKSCDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Y8</accession>
    <name>A0AAD5U4Y8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c oxidase assembly protein COX20, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004550</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000324">
        <property type="protein sequence ID" value="KAJ3219870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4Y8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022533">
        <property type="entry name" value="Cox20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586">
        <property type="entry name" value="CYTOCHROME C OXIDASE PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12597">
        <property type="entry name" value="Cox20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02049">
        <property type="entry name" value="PROTEINF36A"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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            <end position="54"/>
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            <dbReference type="ARBA" id="ARBA00023128"/>
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        <source>
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        <source>
            <dbReference type="EMBL" id="KAJ3219870.1"/>
        </source>
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        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
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    <sequence length="99" mass="11178" checksum="2674682AE610CF7A" modified="2024-05-29" version="1">MSDKKLSSDPKDVIKDIHAADFKPSNFLSMPCSKKALLYGVAAGSSIGLIRFYVSQRLRSAGHFAVFTFAGVSILSWEYCRYQRRLVQIELDKMGQQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U516</accession>
    <name>A0AAD5U516_9FUNG</name>
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        <submittedName>
            <fullName evidence="6">Adenylate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AKD1_2</name>
        <name evidence="6" type="ORF">HK099_002956</name>
    </gene>
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        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
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        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
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                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
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        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
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    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
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            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="284"/>
            <end position="316"/>
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            <begin position="287"/>
            <end position="314"/>
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            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
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    <sequence length="665" mass="75250" checksum="5D11F01C601B7A2F" modified="2024-05-29" version="1">MHTEGKVNAKIKDEDNITKFIEKIPAENAIKKVSKPLFILVGKSGSGKSTVANKLAEQLGSKVVSAQTVLNKEVHLIDDEIHDRLCLHLYSGKEVATSKILEAMEAAPKKDSLKFSGIILDDIPSSSATIVEPSKPNTGERPVLKKIKKRVTKSASSSATYTQPDLTTTSTNVQSCNNTAPNTPTSEIASKFSSNTITEFSLIDRLTSPQCDRPASTRSRPGSRASKLETIPDFIPVVIQLNIEDSSLKRRRKAQKIDPLTGMIYSAQRIKATLEAQLASKNKFLNEEDENQEEAVENEEENDEMEEENEEDEESKIVDEEYLNFNVLDNMNEEENVDLKNKTKKKGKLNINELKKVKLSNKQNYEPISDEIFKRLLRRSEDFEENIDRELLYWSQSVEPYLKQLKVKSTRQKTSNYNFHYIEINGSQHPDVIIKDVMHRIDTLGLGLNLKTIFPKILVPLDVKGKSEEDIVKIYSTLDLEPDEPPRELGNWGKYCAVSFVNDKILVNASMTYVVAYAGFIHFFANQKALNQFMENPNKFLTCPTQIPSLKICILGGPFSGKSTQGTLLAKIYKLKYLNLDQILSKWDKNPDQTNLIATNQIYKRVRNRLRSGKTISAAMEVEIFKFVLNQMDEDEEFEESAVGESSWLLDGFPRTVDQVTQYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5D4</accession>
    <name>A0AAD5U5D4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Plastin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PLS3</name>
        <name evidence="6" type="ORF">HK099_002690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
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            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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        <property type="entry name" value="FI19014P1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAJ3222111.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2363" mass="268210" checksum="390640233EFB29D0" modified="2024-05-29" version="1">MGETSASTKAPNKMTLNSNENTHHFWSEAETAAYVDWINLQLADHSDLSGILPISKQGTALFEACHDGILLAKLVNSSVEGTVDEKSLTRNCKIPIHKSQNLIKVLDGCRAIGVQVHNIGPEDIMRATPHLCLGIVWQIIKFGLLANVELSGSMEICNFGSVDSVNSDSSKPSAPLSHSRSKSTRVYSSEKALLTWLNYCVEKTGYTGRVTNFGNDLSDSMVLAHLVSYLTPAENEVLSVDSVQAEEDLLNRAEMVLAAADSFGCRQFASPTDIVEGSKNLNMAFVAVLYNNRAAATEAEIKARKLELELQNLEKLASEKLESEREKAKQNNDLLERDFKEKLENSEQVKKSIEYTNAQLHTKIDELLVKISILETESSTTRQTLEISLKSEHDTRELLQAANNEVAFTKNQLSAIEMKSHDNLRNLQEKLNYVSDELETAKESSFNASEESKELAAEIEVLRADYLLKQEESSKLVKELESQLAIAREENNNLKNELGESKKENEDKNEEIQNLQKRLADAEKEFGEKAENLAELRKEKSELENQLDELSEKLNSSQQTSFEESEKLRNALEITKARVSEIEKECDDIKTESGNKLDSVLHDLSILETKLSEANSDLGQQNKTHQNAVEVLTNEMRSLENYYAEKEIAFKEQLNNAIKDVESACKVAKEAKDHEEKALETLHQLEKEIETFKACVPADSNEEITTRSASCSPSENLDRFKDILDRLELQTQARKDASEVAAKESEERAKLQEELLEATNRLASLVPEVKELREKIENFEKETNSGTAQHSELVKASQNVVNNTQVTHHLVQNVHNVHNHHSVHNVQNVQNVLNVHNVHNLPSTSVHNVVHSHTVVNNVHNVKNVLHINNVQVQYAESSVKHTEMISDTRPLQLEYNVSTEPIQCESENQVVADREITAPESAEDYERRYNQLVVDYHWLISHHSEKPEADIISKIKDQIENMKEYTTRTNVHTETHTNVEVFKTVEINSGLEEKDTEDILEELQDKVAELETLKKEKDDAIESAQIERDVSSKLQKQLSHANSKLSTLTSDLDIVVQRSNSSVVPFKEVSRQQSLANAFSSLKEVKSKLELLESTPSKPENEQFFMDEITKLREKLHETTTTVWELSSLVHNLSVQDQINELTKSLSDRDYEISDLKKEIFEMNNDKRNLLVQNEKAVERELSKICSLPSESRFASHAEAEPVEEVERGVSHYSSGPRQKKFQKANSQFPETEFERAASQYSSGPRNVIAKNPSQFYDANNGAQSQYSAVQRQASKPAELVKKGTQYFEAPITSNNSEAPPNRVLERENSRAQQPVEAHHSSHSTGKFVHTHTTLENVHNIQTNTHSEITKVVYVHSKEELNKVRHNLEVALAQADHLKAELSTLQSSSHQYEDELLEEIARLQKQLRETDTKIWELNQIINNLAVQDQINLLSRLVSEREAQIDDLKNDISCLIDQNESVTNREVAQETKLEEEKSIVEKQFSNVEQLIEKELRTTITSTEQTRHFVITGQELKDREALLTKLQAVINLMKEYHVQRNLALESAKVEHQDNVQLQKLLNAANQRISDLNEELSQVKNRLIRKEPSALPDLAEFENILASEMDNLTKKEITVNVTETTKTVVVEGEGMNPEVYVNRDVEISGDLDQILQQLRTRILELEAEVQLLNGTEHAPALSLKDKLKASSAKLLELEEKFSNEQPSSSELENLKKLLQIKTQENKQQSLARLVATEVAGEERMKRLASEQKASDLLTEIKVLKDCLSELDQEKLDLQQKLIRSEELRAELNEENLYLTKLSNDEIAEKDARIKGLKEKMEQAEITVVRKITTMEHVISSESNKHKNLLRQMSVAEQNAKGVDNELESLKERCENISKEREELSEKVLELEKEIEEIKGEGGKKVIIEKEKLTEKEATIYNLTIKIDALRKQNTDNNLLAINSDEATVQQKLNETELKLSEAIGEIETLNNRLEQLIKEKDEIIDAFKHNKLKALDQKQKSDVNFWKAEDGLKEKETKLANAEEKLEKLEEQLAQSIFESAKLEEEHNQQNLAQNEELAILRCRTEDQKAEIESLREAIKHLAIDNKRLANRNSSIEKAEKCIRAEAEAQLKRSLDDIAGRDEQIRSMKERLDAASRVEIARKIAVEAAAMESYDNAQLREKLLQAVQQAEDADEIARELTEKIKKSEEQSEFLKEKLNELEEESTALKRDNYNLLKSSLNSLEDKDKQINNMEDKVKDLAIQNKARQKAIETAATEQIERIKLQNQLDSTLRKYEEAARLAEFLNLEISKIKSGEEMAELQEEYCHKREKDHEKNSLQMNKNSSKSKESVATSSNKNLAGSTKSLDVKKSKSRQGSAAPNTSSRSIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5H4</accession>
    <name>A0AAD5U5H4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007389</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000071">
        <property type="protein sequence ID" value="KAJ3225102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5H4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03193">
        <property type="entry name" value="GST_C_Metaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026928">
        <property type="entry name" value="FAX/IsoI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01180">
        <property type="entry name" value="SUF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01200">
        <property type="entry name" value="SUF1.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like fold" evidence="4">
        <location>
            <begin position="74"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="3">
        <location>
            <begin position="229"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="324" mass="37356" checksum="5399DD853483ED0A" modified="2024-05-29" version="1">MNSITPYLIVIVIFASLILIFVTKKVLVNQRKKHFSRNFPPETKEAAIGEERDPSLIYLHIPNLMKWGNPNASPYSLKLETWLRLNHIDYVVVRDFDLKSAPKGKIPWIEYEGKKIGDSELIINYLSEKLNIKEFASVDGDTSTFNLNEKIAVSHFITTLVSEHTVAGILGYQRNYEYFEETLKAYTGMDKLPFYLKFLASRIKKGTFNKLKLRGLAIHSRDEIYFNIGKKDLQMLSLFLGNKKFFFGDGVSRVDASVFSILASLAWIPLVNSPIKLMILNDPEFLNLKNYLIRVKDLVWKDSKIPWYIGEDCVVRSNTIPFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5H5</accession>
    <name>A0AAD5U5H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphatidylserine decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.65</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PSD1</name>
        <name evidence="12" type="ORF">HK099_000678</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism; phosphatidylethanolamine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000117">
        <property type="protein sequence ID" value="KAJ3223785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5H5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF6">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3223785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="283" mass="32519" checksum="EBC8112BEC1EA4A8" modified="2024-05-29" version="1">MSNLAEAKEEDLTKYENLAAFFFRELKEYARKVEYGSLLTSPSDGYVLYRGLIENGKIEHIKGFTYDMNALIGVEEQNSNLFKKGRLLRNNTIEDVDVEIEKMKSSVNDEVPIIYNNEYKKKDNLFYCVIYLAPGDYHRFHSPCDWKIEKRRHFTGELYSVSPKIVNTITNLFVLNERVVLSGKWEHGLFSFIPVGATNVGSIIINFDEELKTNLPDRHILDPPGTYNEKLLSKDVQQGEELGGFKLGSTIVLLFEAPKNNFKFDIVPGEHVKMGQRIAHLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U609</accession>
    <name>A0AAD5U609_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCA7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U609"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904802">
        <property type="term" value="P:RITS complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013243">
        <property type="entry name" value="SCA7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037804">
        <property type="entry name" value="SGF73"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805:SF1">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08313">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51505">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCA7" evidence="2">
        <location>
            <begin position="178"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="312" mass="35170" checksum="5530953E8BA434A1" modified="2024-05-29" version="1">MDKSWQEMKKELGFNDDSDSLSQMQKAVGFTLKETLTTVICNLCSKPIIQAQLINHLENCKKCKQQEKKKLKKPNIMNEFPKIVSSDTNTPTVLNSEDPSVPPVKKKRKYTKQQSDASEKKIKLSELSEYANQLNLKNSQVGGKTLGFGSVNKSGTTFTINAKKYNDTSMTKEKKEPKKKEKGPIDLDKNCGVETETGKCPRSITCKIHPISAKKAVVGRSHPFETLMSMRERDKQLGQAQKQIVQPVFSHNLNNFDSISAEEEALKLILSIKTFQPKPIAIFPSNGNFPSLKVWLEKKMQFDLENSLKESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U633</accession>
    <name>A0AAD5U633_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Microsomal glutathione S-transferase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001967</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000161">
        <property type="protein sequence ID" value="KAJ3222752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U633"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF22">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="18235" checksum="5BC2F961D6129384" modified="2024-05-29" version="1">MSTFTTITFDSSYGYVLFTIVLTQLQCMIAGISVAGQRKKHGVKYPDMGCGIHAMKLKEKDWEEFNNYQRVHYNYLEDLSLITIVTLISSLKFPILSAQLNFAYVIGRYFYGRGYKKSGASGRLFGVLILDVAKLSLICVALYNCYTISGLKYSEIFYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U667</accession>
    <name>A0AAD5U667_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U667"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF14">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3225903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="463" mass="52336" checksum="9E3BC5F39BE540C1" modified="2024-05-29" version="1">MGKKEKNSREVNYDTKPIGTNKNRGCTDLPFLILFIVFWVGMYIIAGVAVETGDPKKLITPRDSRGQYCGVDNSKMPHQNENSNMDLTSKPAFTSKPLSVQICVEECPTSTRLVTVDDVYCNYDVPPITDEVDLLIYISDNRCNWFFYESKPILGRCVLSNFTIPEIPPKVSEALGLNLDELINSGGVLANSKETTMKVMTDIINAKWFIVGGTVVGFVICFVYLILMRLIGKLLIWVTLLATNALLVSCSVWLYFYWQEYRLWYEQLTPEVKTDADLYELYGITAGFFTCAAITAIILLISIFLRKRINIAIEVIKEAAKAIAAMPLIVFFPLWNFALTIGLFAYFCYVYVHIITPVENVSVTSFGYSWTDSKVSFYLEWYHIFGCLWGLAFLSGVNQVTFSGAIASYYWTLDKSKLPLAPIISAFYRTVRYHLGSICVGSLMLAIVQVIRLFLYSFQKQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6C2</accession>
    <name>A0AAD5U6C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Ribosomal RNA-processing protein 8</fullName>
            <ecNumber evidence="9">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RRP8</name>
        <name evidence="10" type="ORF">HK099_005490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6C2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016433">
        <property type="term" value="F:rRNA (adenine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2150:FF:000001">
        <property type="entry name" value="Ribosomal RNA-processing protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2150">
        <property type="entry name" value="Ribosomal RNA-processing protein 8, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007823">
        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05148">
        <property type="entry name" value="Methyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00076672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3226137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="329" mass="38011" checksum="96410D57E13C3530" modified="2024-05-29" version="1">MKIEKSKLRNLLRKKKPYKNEVSLSNLPKESEDSLDYQKKKLEKKLKLHNVEKNPNNTTKSITTSSSKKNLTSLQLKMETKLKGAKFRWLNETLYTTESSESLKIFTEDPELFTIYHNGFRSQVQKWPVNPLSIFIKNLEKRRSFHGELVIADMGCGDAMISQTFKDQKNFKIHSFDLIAVNDSVTSCDIKHVPLKPSSVDIVVFCLSLMGTNFFDFIKEARRILKVGGEILIAEVESRFPKKRKFQEKDSLLSKSNNTKFFSEESENGIELFLKNLQIFGFELKKPVDFTYKVFILFHLVLKEKKTGSNGAKAIDGKSMLKPCLYKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6J6</accession>
    <name>A0AAD5U6J6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000206">
        <property type="protein sequence ID" value="KAJ3221833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000016">
        <property type="entry name" value="Adenylate/guanylate cyclase domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050697">
        <property type="entry name" value="Adenylyl/Guanylyl_Cyclase_3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="6">
        <location>
            <begin position="1064"/>
            <end position="1196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1310" mass="145623" checksum="4D9936128D6918A9" modified="2024-05-29" version="1">MPKTSNEKGLSEFELKNEYQAEFKGSFRKSKIRSQSSGLINFQNSVCCEQAKKGTKILPLSYDTTLGEIALGAAVEQEKKIIKKYVYSTFQSMKCNPSAAVSKIKINRNAIESQAENYKRLYTTNPTAPPSAGAVVHHSIQKHLSSPGIKRPISAKLRPKSAPASSLKQEVYEKEAGKPNSDKLNSIAGRLNETYQTYPPSLPGQIPPRIHQTTQIQIVRQRKSNIKNILNKNDPNNSQKLANSTSASIAVTAKKPISETLNSLTESIKENSNEIKKDKNILDETKKSKPSWAVAKEKIFGGEKSKYSQFRKVETALKHLSILTDTDVGEDEIRNSLEELIEASRFDSKFTSTTLYDSGAVNILLDLLPRISNNWELQYRASELLKLLADSNELTYFTIHKKNGIASLLQTIEVLGKGNEKRKIIIKTYICKKNSQVAIDNTQSKKSSPWAKVTQLANIVRLKQGSLLENKSAATSVVALNQNLSNKVPIISITEEEEDFEKIKNDYSVFHDPSSLVHGLLNNYFDPEFTQNLDRMDRNHKTQVINHLLSLFEKVDKILAATMYVSLEVDLIQAMEQIQWDATELVQAQSVKVYLLDEETKELYFPQEKENSSRSEEIRFLANTGIAGWSANNDETINIKSDASENELFDPEVDLFDNKGIEANSILCVPIKHPSGKVLGVLEAINKINSISTGVLAEKASTVNGEEENNNFFSEEDENLLKILSKQSGLVINNAHIYESMLQTQKKVQVLLDTTKSLGSTLNIDELIRMIMDSAKNLLTADRCSLFLADGPDNKSLLAHVQGPDSIQDIRINSNQGIAGYVFTSGESVNIPDAYSDSRFNPAIDKQTGYLTRNILCMPIKNVSGVSIGVTQMINKHSGPFGHEDESILGSFSAQAAVAIEKSYLFKQTEDIRNYLESILSSITSCVITLNESLQLMTINRDWVLNALNVGQDFMRANSILNWLGDSNPVFLDDINKVLNTNIPIYSAEYSLQSTTDKKTTKFVNYQIMPLIGNVTKGLVLVLEDISSEKRAIMTLGRYMSPALAKQVMEEDGSQLGGKRKKVAILFSDIRSFTSLTESMEPHMVVELLNHHFSDAVNAILAEQGILDKYIGDAVMAVFGVPFVNPDDSIHACNAALRMRASLKIANEFRVSNGLNPIKIGIGINTGMVLSGNIGSEKRMEFSCIGDAVNLASRIEGLTKNYNTSILITEYTKNETGDMFWTREIDTVVVTGRSNPVKIYELIGRKPSSLNASNTNFSLENVINTPHEEVLHQLPMNLEIAMSYYAKGLELYRSAMFMEAAENFNLAIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6U8</accession>
    <name>A0AAD5U6U8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribonucleases P/MRP protein subunit pop1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">POP1</name>
        <name evidence="7" type="ORF">HK099_004711</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000034">
        <property type="protein sequence ID" value="KAJ3226535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6U8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039182">
        <property type="entry name" value="Pop1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055079">
        <property type="entry name" value="POP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009723">
        <property type="entry name" value="Pop1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012590">
        <property type="entry name" value="POPLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731:SF3">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22770">
        <property type="entry name" value="POP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06978">
        <property type="entry name" value="POP1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08170">
        <property type="entry name" value="POPLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pop1 N-terminal" evidence="4">
        <location>
            <begin position="43"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Pop1 N-terminal" evidence="4">
        <location>
            <begin position="129"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="POPLD" evidence="5">
        <location>
            <begin position="461"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="6">
        <location>
            <begin position="676"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3226535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="763" mass="88445" checksum="A154E5777725751F" modified="2024-05-29" version="1">MSNSKGIRDKKRQKQQMFTMDASLKKQNNPITVKNYSLNVTDFAEARAFEIKSMENALKHQTEFYGNQRIFQRIPRYMRRRAASHNVKRLPTKLRIKALHQMSLDSPRKEVKKSSRRSKRRTAVIAEEFGLRQTNKIWLDTHIWHAKRFKMCEKWGFALPITPNDKSDRSLYKANKYQATLNDQSYKRIFVFKGMESNLIFYFQKVFDPLLSSIKSEKYISGKRFGSQILYNIESFPKHTICPVEFLWKQESDVNFKEIRTLWVFIHPAAFIEAVDVFSLLSKMALKDEKNFNFEILEPSEVSVFDISGPRSHAILSAVFKLAKKGYDDVYINDDAHNMWNNLKHLGSPSSLSEGVVLSLTIQDPRLSFPPKVPARKFEPIFTPSKLDSVLTNIWPTPEQGKCLAISSIFSKETLNKVESSKLNNAKLNALKGESLIPGSFSNQENVSTAIPILIIQIYDGWKIVIPNSFGRSLFHSLVFSGARVFGLADLRRLKYYESNLKPSFPEDWCGTKSYQNYQNSLTEEKKKKYYNLPPAKRGFSLEKWPTKSFGVDFNYILQDSTELDDDSMVVDPKNIFCINSPVLINIMNETFFFNKKNQNFKIELQALRNNSDYIKESFSVKIKHLNTAKQFNIFSFFESIMRVKIILEGEGTLKDDSLIYFLDSKFYNGYYLKQKLFNKLIDEKVIELDNFPSENLIVGFVGYGRFSYSKGKCTGLGGIGFKKYYKNFFEKENLKKDDADLNLVLVRSFGSRVARFGRIMFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U734</accession>
    <name>A0AAD5U734_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U734"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436:SF3">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="POLYKETIDE CYCLASE SNOAL-LIKE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="454" mass="49840" checksum="9B6193FE54F5F9A2" modified="2024-05-29" version="1">MSSLETLLNFRQSCQQNLGSNQIPEVNSFFKENPTLLYVPTGVSANTTSDVLRLIKEWCNVKDLIKDELIVSRTTSFSHIVEETVVTIIHDEVVPWLLPNVKPTNRRLVVPLVTVYNFDSNFKIISQHVYWDQASVLKQIGLLPNSLFCKANNSETVLPICGIKIADPLLLGAKSSNSSISVQNIIKENQQSEQNTEKMTQAPVKLSKKSSVADVFSGEKPQEETYHSSTRVFHPPGGISNIFNSETPTPSQSHVSKKKTNLSSLGDVPAAAEAAELTAGNKRFSTAGIRSQIAFGVDEDVPFTTHRKMSSVPSTQSHFSLDGSVEEGNLVHSQKKHNPDANRSHFSLAGDVDGKEELHFSKKMSDKNAYDTHFSIGNDDNVQNGANEFIPSKKLGLGSQFESHFALNGGKGDNTNENVRKSCIRDHNAASIQINQRPSSRVLGPPGGKSQIQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7B3</accession>
    <name>A0AAD5U7B3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multisubstrate pseudouridine synthase 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PUS7</name>
        <name evidence="5" type="ORF">HK099_003352</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7B3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02576">
        <property type="entry name" value="PseudoU_synth_ScPUS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="entry name" value="TruD, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00094">
        <property type="entry name" value="tRNA_TruD_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326:SF21">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE PUS7L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="4">
        <location>
            <begin position="288"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="584" mass="66525" checksum="6020F20F931693BE" modified="2024-05-29" version="1">MEELKRKFLPSDPDLKPSTLKKSVRFGITCFVSQSKKPCALLKQSYQDFIVNEIHNGVVERLTDLNPPTSKFSSLSKEAFVEKLSMLIPKEEANTISNLKGSETHNISVILEEKSKRQQVHDLIKTFPPLASKTKEDKSIEIFFSKKQRINWKDLGGDYLEFLLYKENKDTADAINHISRLIGCSTKIFSFSGNKDRRAITLQKVTAYHVTAENLAQAVNKEGWLVPNDKRRGCIRVGNFSYCKNSLNLGDLDGNHFAITLSIRRVELGSESPEVFIREACESLQNNGFINYFGLQRFGVLDVSTHEIGVQILNGNYENAVNLIMKKKENEREDFTIAREHWEKNKNPKEALNLFPYSCVAERSILSYYIKVEDAFRTPMKALSNHMVSLRIKTYGMKLVVGDLVLIKEKSLHSSTTGGRNPQNVLILNEENLQKYSIKDLVLPLPGYDIIYPTNSIREEYKNFMAKDNIDYKGMKREERDFSLPGNYRYVFASVQNLKVTALSLNEMDIKNGLKVPDSEIGFLVSDLYINAFNLGGSKLAVVLEFDLNAACYATMVLREIAQCEELDKTEVYEGNDKKKPKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7J0</accession>
    <name>A0AAD5U7J0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7J0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042183674" description="Ricin B lectin domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="281"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="528"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="652"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="773" mass="87448" checksum="A686B1FF214A19E7" modified="2024-05-29" version="1">MRFLLLLSVVSSTVNQYYWDSVAPGTTFGTNNKLLYNGPGNVIFQLQTDGSYGITYNGFINEPFKREPGVGSTTPHYTFTLDSDGHFTLVKSEDQGDTPIDLANAQGPTNSPFKIFVGGDRRVRMIDARQSTIWTYPRDDVVVTRDRIESNMASRPNFLRNNERLTSSNKNWYLSMNSVGMLYTNTGYTFNPSNGDGIDVDYRSIVLNEDATLSYHLIDGTVIPVTDENDGSRSPPSTPSQISKYRMFITDEGIIRIQDIRGVVLWNFNIASTGQPVGLSYWPIILAKTGQCITAMSDKSISLQACSVTSENQYFTYHSDYLRVKSDPTKCITISDGNKLVIDKCSTKSLFNNVEQDFTIRTLDRKKCFHAANIVELLPCDLTDNDELFTWDMKYVPLKDTDFEAIFTMNLDYRIGSSEDEIELKPYNNKQTGKWAFKDGKLRWNISPNYCMDDGGNTVVLKDCSTASTWTKLITGQIQSTKSTNCITYDYKTLTLSLEYCNTNNNMQRLYFSRTDSIDDVVKNEPAKNIILISEATGLCLSTSDNNIRQEKCNSANNQLWNYRLDGKIMSVGSKKCVNNIDINHIGMGDCNSERTTIFKNIGKENYMFETKDNMCLDIGGLDPSMTWLYSCMSTNGNQLFTSNIIYSSIDYGVIQLTNQDKVIKLNEDKSIVLSDKKIWEPSQQFYLTAENKLKNSNNGCISYKNAEDGVKLFLDYCYLAKKFVFSNDRLQSLTDHQFCIDNSGGELGNGNPLQIWYCITGQPNQLWKMVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7K7</accession>
    <name>A0AAD5U7K7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PHD type zinc finger protein with BAH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SNT2</name>
        <name evidence="8" type="ORF">HK099_001427</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000014">
        <property type="protein sequence ID" value="KAJ3227578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7K7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048189">
        <property type="term" value="C:Lid2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036205">
        <property type="term" value="P:histone catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029617">
        <property type="entry name" value="Snt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BAH" evidence="5">
        <location>
            <begin position="93"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="6">
        <location>
            <begin position="508"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="834"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="597"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="606"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1118" mass="129473" checksum="8122B30D51CE1EC5" modified="2024-05-29" version="1">MCERCVFPSSRCVQNLQNGVTDTSTEKLTTHFQNCLPSEEWSITFNCLPDFECKNFGAYAKCDWMKGHPLANAINSLQEITMMIEQITLSNGIHYRKDDFVYVEQGENESLPYLICRIISFKNINDKTFFLANWFYRPNETYYRTNRKTEQNLLIASMHSDLCPVSSIRGLCNVVHSHYIENLESFKQCVDSFYYEQLHDRYTKKLYDVVPLDFVNLPKEYKQVLKNYQFILVAEGDSGKFTTDRYCKLCRKWTDPSTSVNCIKCSGCHHLTCVKLEKKNLTKGYAWQCSRCLRDYFKKNEEKFFCNGTVRKLDDEIDKLDGNGEKNMEEVNSNLADELAKRNEFGLVSLLGDEKGFPKSASRIGIKYQAEVPDFTSVAGNLNNGALIEDDVFPDSASTTRSATPTSVKNLIKKDTKKKKTYLKQDSIIERGGKSETVFSSSSLTNFDLEKLDEYFENVYSFVSNTQFPPRNCDIFDKALEQLSTDNYEFDIALEKMKLMPLESLNIKKWTLDDVSDFESGVTKYGHDLEAIHKEMKRKTMKDLVPFFYTWKRTKRYEHVYSKYCKVHRPQKTFKKLITSENQVNSRKTLFETLDNLPIPRSNSQDDLEDSISDSDEEDDTFGKKVKKKRGRPEKKQKLEKKIKLKKTSEKPLSLNFECCNCWNEESLQWYNKPISLIDDQNDALFQNQVLCEECYVFWLKHASLKILSKAVREKAVKKRKLEFSDNKKPKITKKPRNDNSENEEEFFGNDEDVEDIVSGDINTEVPSYVEKKTGCAVCNALFSVAENLLVECSQCLLKVHQKCYGIASSFLSDKGQFDCDKCVNEKNREVSIIYECVLCTRVFPDRHQALKRTIGSNWCHVQCAVFIPGVIFGDFENFNSVENRITCQICDIPNKGATIKCYEKNCSRYCHITCGQEKLWEFVILEKNVKKKNLMKNNIRNNIFGVGYCFEHRKNKPRQSVGTQSRLNYLDDVAKNQSNLLKEYVKAKSAVDNEENQFVNKICKGEKRSISWQLKNSCSCHIHEEDVKETPKNINSKGVYSTKVYTTALTALTKNPAQEDEKEDDESQDDYCCDRCEIDVSAFWWEIDDLELDSTFGGIVNKIIVCQKCFWENKNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Z6</accession>
    <name>A0AAD5U7Z6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPI inositol-deacylase</fullName>
            <ecNumber evidence="10">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">BST1</name>
        <name evidence="12" type="ORF">HK099_007324</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Z6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050185">
        <property type="term" value="F:phosphatidylinositol deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006505">
        <property type="term" value="P:GPI anchor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039529">
        <property type="entry name" value="PGAP1/BST1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495:SF7">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495">
        <property type="entry name" value="NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="11">
        <location>
            <begin position="8"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3228043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="465" mass="52986" checksum="025A81B053B6B0F7" modified="2024-05-29" version="1">MNLYHPNNEEFSAFHSQGIEDQAIYANAVIKYILGSYKSSGFAKPRSVIVIAHSMGGIVVRQMMTLPEYMPGSVSTIFTFATPHLSPPLSINLGIDLLYNRLRYFFSNGISVKNLVFVSIASGNHDFLVQSDKSDIESIIPEEIGFTVYSNNIPEVWSAADHKSILWCKQLCVVLSKALYDLVDAKNPQQLLEQSARLQKLKQRFLGPTDNNNFNAELKLKDFSSKKISLYKDENVVYKAISLNVSIFEVQPKNSLIIFTNIDSSALTIKLCIKQEFVVESLQLQCIDSHLNYFKIIPHFSPIPLEKVSQEHERDLKAKNLYYNFNKHIVGMDGESLKFYYVLSVNEVLKNKDVFLIGRIVEKSFGGEFVVKQTNPVTAFKLRLLQTDLFKYNLYLFSGCEDEKKKENLTSVLTIEIFNSKLCSKDFKIKFSIDWRGSFGQLLRNYLPAFATLPFGYLSSADFFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8B6</accession>
    <name>A0AAD5U8B6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chromosome transmission fidelity protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CHTF8</name>
        <name evidence="1" type="ORF">HK099_002896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8B6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018607">
        <property type="entry name" value="Ctf8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47475">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47475:SF2">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09696">
        <property type="entry name" value="Ctf8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="124" mass="14581" checksum="59E7CD27E518113E" modified="2024-05-29" version="1">MILTLNNTINQIVSGKENQDDQEEFILIDLQGSIQFNKQNDKSVADLHFVESTPYLTIGHHKLKGEKVILKKPLGVLKKKNVNNEDQETNKETPHIQLDMIYVLKYKYLFKERPEYLNYNNNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8G5</accession>
    <name>A0AAD5U8G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor IIIA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GTF3A</name>
        <name evidence="8" type="ORF">HK099_002914</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8G5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF139">
        <property type="entry name" value="PAIR-RULE PROTEIN ODD-PAIRED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="257"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="324" mass="37237" checksum="CBF532C7ACC0E272" modified="2024-05-29" version="1">MNSLPAPSSPKWPDTFTFPSSSSPEPVYSPSDSSYYSDQLDHFQLSNHPSNSLYFHDDFPSDINHPSDDVVDVLSDFNNNSQHYEVSKLLTENSLNNFNYVNKISVIPKIVVSKPSDFDVVAKKNNQKYFNFQESQYIENLENLSKLNLITESKSISLPKKKKNSLKTRTYSSKSATAKKNILKKRESQSFINEKIPDAIKITCPETISKSNLRTCSNGERRKILYKCPKEKCEKLYTERFNLRSHYISDHLSLRPYACSFEDCSMTFVRKHDKNRHEKLHIKDSKTLNICLKCDKTFSRTSTLKHHQTPGADGKPSPCETQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8H6</accession>
    <name>A0AAD5U8H6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8H6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="203"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="368"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="44705" checksum="8966B2561B30C4A3" modified="2024-05-29" version="1">MAVDIKLWAFGLINQFLIDNNLLETAQKLSTEAADIMEDLPNMILPEHSVNRSLLSILETYQCMNLSNSLQNVKLEKALDVEVLVKPNGAFPKKQEKIFDLIHNGNVLCCKIFKVPLATFPDQSSDDIPQFSTFKVLVTSGTDKLIKFTNLTSGKLIIFFNHHSGSCLDFDQHPVNLNLILTCGMDGTHHLLDLTTCQVRKSWSDHKKYVTGVKFSLEGNNFATASYDKSVNIYREDGTADYSLVHKLNFGGMVERDNCLHQITMGGNYSHSKTNMNENQDDWVSFTPMHLEGAPSGNHILVYTDSQAGMLTLVRKNGGQVCSFYGTSVDGFSQPRCCFDKSGAYIFATSDDKIFVYEVFSGTCVYKLSGHKGLIRNIFYDIESGALVSCSFDGTVRLWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8L5</accession>
    <name>A0AAD5U8L5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8L5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="848"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="919"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="850"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="923"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="981"/>
            <end position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1006" mass="114975" checksum="8879EB81FD0DBCAC" modified="2024-05-29" version="1">MLRDMKEMEMEFNDAPRIIKGLREEATALKLKEYFGHLTSDTRQLRGLNKEVRNLKEQNYHYQQLINEKGLDEREVLKRDLDESKLNLERQIKFTSELQHRTDLIEKNLNLENKNFRIKIKNIKEENYVYKNKTDNLENLLKEKDKEIASLSIYRFKAVHNKSSKDQICKVCDKREKDEQEKQKLKLLIDRLPKVNLKPLENQSPTEIELILNFDFKPLINFEWDAIFVRCFEDSKNIKLLKEFKLNYKEFVNSSEVKEAINFSNTSNSQQTMTKVNVKFSNLKNGAYYYFDCFSAFQGVRGEAFKIESGILADILPEKPNKPSVSIKIRNEAPEIELLIDSVLSRIGESKIRKYHVYHSNFPDMSDKFLIAEIPSDTFDPEEEVTVDDREKTLFSETKNEVDSNVVSENILTMETEIIEDHGNEEQDIKNPLSANALIESDNNSHDSFKEKNDVIETSAESTSVNCEVDCGEKNLILAVKDTAEYKVDINAINMMLPQEKKSCETSKVKFCYTDPTLLTEHYFSVTAINGSGEGPHSDTTDCIKIDVKPNTPSKPIVERISTHCVKISCTVEKNLGSEVTSYKLKLFKSQKKGYNSNDLNISNKSKKKEIIVEKKTNTEIYEEEEKIKENNLIEEEILIAVRGNEKKFQEHYSGNNVDDFNMEEKGSSENVNFISCTKFTYVLDNLNLGYNFKVKVLAMNDYGFSDESYFSDEIDLEHMIPTPKILPNFKIISTTSVLFEFRDNLKICENNLQLSNLQKADEESPFNSHVIGRKIYSSFEHDMHGAVVEVPFIDLKEKFLCLENLNKAQQYYFAFSYISETKSEGSLSNSMFIPLAAAIQLPPSPIERLTSNLSGTEDKPTSATSNQLSQQHPLVHSQRQSLSLLGNKARTSKYLNEISTSNLSLNQKLVNMHNGYPAHSEINLSQDHSNSDDSNIQGHLPPDSVVNPSQQTVISHEPHGNAAKDSSSNVAISPKEKKSVGNSSNLGRHASRISNISVSRTLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8Y9</accession>
    <name>A0AAD5U8Y9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="5 16">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">DGA1_2</name>
        <name evidence="17" type="ORF">HK099_007652</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Endoplasmic reticulum membrane</location>
            <topology evidence="1 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="5 16"/>
    <dbReference type="EMBL" id="JADGJW010000076">
        <property type="protein sequence ID" value="KAJ3224932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8Y9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3224932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="303" mass="34747" checksum="ECFAC1156E191BBF" modified="2024-05-29" version="1">MVKTFTLFANSKMAKKPLVKRIKEVISSAHKPSKGGNKKSFKTIRFVDDLIGMKHFCDYMDLDLIKEEDLIDGPSYLFCLHPHGVLGYSHYANFMSTYSKFYSLFPKISLRTCTINLNFKVPFARESFVLRGFISADKESINFSLNKKNNDASKINAVAIVIGGAKESELAIPNRNTLVLKNRKGFVKIAIQNGSSLVPVYSFQENNLYKQIENKTIKKIQNLFQKYTTFRPVLVYGRFGTLIPFRTKIVTVVGKPIKVAKNPNPTEEEINKYHKQYILGVREIFDKYKDLYAKDRTEDLIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9I1</accession>
    <name>A0AAD5U9I1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_006749</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000060">
        <property type="protein sequence ID" value="KAJ3225476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9I1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="13">
        <location>
            <begin position="159"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="424" mass="49391" checksum="4E3A06A0C4426B86" modified="2024-05-29" version="1">MQRIFLNVAIIFIITSTLLLFLYPKGNYRENLDSVLDLKFAAKKFPDEQKTMNSKNKAAILEQKIYKLIKENANYELSEEKKDKLRNSNAVQIEKTDSTELEEFEALDKIFLMKEKQVEEVIKEEDVKEVEEQFMDSTIGQEEAVSKEKSEIYETTLITETDVLFVVLTKEEEQETRIPAILETYGSNNNSNFYFFSRSELKIRSDLENFIILPDLYPLKLHTQKKLFWDALKYTYEKVQPDVKAKWVIVVTDKTFVNIKGVLDFINFKEKNGISWFSPHILGKCLATTLNGSKLIYTDGGTGNILSSKLLDVLNENGYYEENKDFLQKSDEYHLNTEASLGLFLKDIFGDKTFSKYLAKNSVHSCGFQENELFHKKCYHSKVFNMKASSLKCKDIDCASFSNCNSEEMNFWFNYYQQKYAYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9M7</accession>
    <name>A0AAD5U9M7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_000041</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9M7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.320:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000004">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="12">
        <location>
            <begin position="449"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="141"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="270"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="550"/>
            <end position="552"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3228486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="596" mass="67946" checksum="A1367ADA0A47E807" modified="2024-05-29" version="1">MTVPISKTDPSSFSNNDEIKVLHVHLDLAVDFSTKKLHGSVLHSCSVVSEKANKIVFDTSFLNIKDIFLIDGEKSTELQYTLAKREGFLGSPLTVQLDHDFLKNEDVRIKINYETTDKCTAIQWLEPSQTVGKVHPYLFTQCQAIHARSMLPCQDTPNLKITYSANITCPPSFRALMSAIPSKEETVDEQKTYSFVQNTTIPSYLIALAVGNIEGKKVGPRTTVWSEPEVVEAAAWEFEGTETFIATGESLLTPYSWGIYDLLLLPASFPYGGMENPCLTFVTPSLLAGDRSLVDVVAHEIAHSWAGNLVTSANWEHFWLNEGFTVFIERKIVEKLHGKKASHFSAILGYYHLKESVDVMMENNTPNYTCLRPNLKGIDPDDVFSSVPYAHFVHFAHKSITTQNFKDYLYQFMESNYGKEKVDILNSVDWEGWFTDVGMPKEKNDFDQTLSNACKALALKWKDEKDLTVLSKLDPSDVTDFTPTQKMNFLDILNNYEKFEVEKIVLMKELYKFGEYKNMEILSRWQGLCLKAEYEPIFPAVVDFITKIGRMKYVRPLFRALYKCKNGKQLARETFLKHKSFYHPICQDAVTKDLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9U7</accession>
    <name>A0AAD5U9U7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SGTA homodimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004422</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SGT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9U7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.420:FF:000005">
        <property type="entry name" value="Hsc70 cochaperone (SGT), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000207">
        <property type="entry name" value="Small glutamine-rich tetratricopeptide repeat-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.420">
        <property type="entry name" value="Immunoglobulin FC, subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032374">
        <property type="entry name" value="SGTA_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF2">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16546">
        <property type="entry name" value="SGTA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="SGTA homodimerisation" evidence="6">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3226678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="302" mass="32712" checksum="00D7580A69941380" modified="2024-05-29" version="1">MSNNSALETRKKLAYSICDFLNQSIKNNTIEDDHKEGIEVAVQCIAEAFSFDLEKDQGNYSIKPATLLGVFEVFQKTQKNLENSNTNSNQQSAESDLEKKKKSELLKSKGNKKMAEKNYKEAIDFYTQAIEVDNQNAVFYANRAAAHSQNGDHANAVVDSKLAIEVDPDYSKAYSRMGHAQFCMGDYKEAVQSYESGLALDPENQTMKQSLASAKAKLNEKSSTTKGEQKSTNPLEALGLGLPGGAGAGGMPGGMDFASMMSNPALMNMAQQMMSNPNMAGLLNNPAVSSMAQNLMSNPGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAW3</accession>
    <name>A0AAD5UAW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_000784</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="74"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="329"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3227679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="383" mass="43655" checksum="2577A955BD155B94" modified="2024-05-29" version="1">MLVKTENLNNIKSDLHSFRSIVENKPKISFKDLTIEEIANLKISNQPLHAKPGETENHFSLCSKSHLSYSLSDFTVLRTLGTGSFGRVHLVKLNCSGVYYAMKALKKSEIVRLKQVEHTLNEKKILAQVSMPFTVNLFCTFQDSVHLFLVLEYVSGGELFSYLRKAGRFPAEVAKFYAAEVVLAFEHLHERDIIYRDLKPENLLVDSKGNIKITDFGFAKFVPDQTWTLCGTPDYLAPEIIQSKGYGKAVDWWALGILIYEMIAGHPPFFDDDHFKLYEKIVSCKLQFPSFFDPIAKDLVKKLLTPDLSKRFGNLKNGVEDIKLHKWFVGVNWDALLKRNIPAPFIPKLLHPGDASNFDVYVEDYEPYGLPGADLHSELFLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBU3</accession>
    <name>A0AAD5UBU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EF-hand calcium-binding domain-containing protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EFCAB9</name>
        <name evidence="3" type="ORF">HK099_002883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBU3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061891">
        <property type="term" value="F:calcium ion sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042798">
        <property type="entry name" value="EFCAB9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47065">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47065:SF1">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="136" mass="15558" checksum="DBE4A7A079553276" modified="2024-05-29" version="1">MLDWKGEGSLDDIQFLTFMETVTDLNRNGSLSVFDIFDLDRSGSVEFDEFYLLICILVAVSNGTGKQFMFQHWRTCFELLDEDGSKASKNILTLLYLNKMGIVSKKEFETLGFLFNFSSKAVDQIYKEFDLNGNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSN1</accession>
    <name>A0AAD5XSN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase M43 pregnancy-associated plasma-A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_000605</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M43B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001144">
        <property type="protein sequence ID" value="KAJ3206179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSN1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042000773" description="Peptidase M43 pregnancy-associated plasma-A domain-containing protein" evidence="9">
        <location>
            <begin position="16"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M43 pregnancy-associated plasma-A" evidence="10">
        <location>
            <begin position="144"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3206179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="273" mass="29880" checksum="ED74DAAD8199750D" modified="2024-05-29" version="1">MKFTILTSILALIAAAPQHNNQWCGTRSHNSAKDLTVSQDFGIRNHFIANQVTVIDVYFHVLMDGADGNLSDQQIQSQINVLNNAYSSSGFQFRLVSTDRTDNKNWYHIPPDSTVEDEFKPALRKGSAKDLNFYTANLGGGLLGWATFPNDYASNPSKDGVVCSVTTLPNGSQSNFNEGDTATHEVGHWLGLYHTFQGGCDEQGGDFVLDTPAEASPAGGCPVGRNTCTGDQFPGNDPVTNFMDYTYDSCMNSFTPGQNARMAALWSQYRHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTZ6</accession>
    <name>A0AAD5XTZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000632">
        <property type="protein sequence ID" value="KAJ3214323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTZ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="19222" checksum="DFE809ACD75F96F3" modified="2024-05-29" version="1">MKTFISYFGRLDLIEILYKEEPNLFTLDNSMLKIAAISNNVHIVNFIIKNIPQVKRDKSIIDAACSFGCFDVLKFLHENNYESCSNSALESAAFKGLFNICEYLLRNKMCEVTSQSLDFACNRGHIDIVRLLFHADKKFGYMAYTENSLYNAVENNHVKVFEFLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUD6</accession>
    <name>A0AAD5XUD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPPP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002105">
        <property type="protein sequence ID" value="KAJ3199475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUD6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001578">
        <property type="term" value="P:microtubule bundle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032273">
        <property type="term" value="P:positive regulation of protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932">
        <property type="entry name" value="P25 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932:SF9">
        <property type="entry name" value="TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="252"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="338" mass="37743" checksum="ECE7E01DAEB45A30" modified="2024-05-29" version="1">MSTSTTEEDFSFSNLKSKFKDSLVLDSTNVVSNENGVKERKNSTSSSNSKTSVSNQILKESNDNNSLRNNAHHTEEKKKISTKKTSINQEMNQLYNLYISFCQFGLTKSQLEGSKSNSTLMSSQSFSKFSKDCSVLQKNVISTIDIDIIFNKVKVDKSKRKINFNEFLVAIGLLADLKFKDIEKNERFGRLITFVLDKGPVSKVNGIFDRLTDTSLYTGTHKLRFDENGNGLGLDGRDSGIDGNTLDRMVNRASSSKARARSLSQSRTNSTSPKKIFENQRSPSPIRNSMPSVFDRLTDTSTFKGTHKHRFNPDGTGRGRDGRVGDEGTKPLSSLIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV82</accession>
    <name>A0AAD5XV82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">rRNA-processing protein las1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">LAS1</name>
        <name evidence="1" type="ORF">HK099_003364</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002204">
        <property type="protein sequence ID" value="KAJ3199033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV82"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090730">
        <property type="term" value="C:Las1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007174">
        <property type="entry name" value="Las1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002:SF0">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04031">
        <property type="entry name" value="Las1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="22498" checksum="AA789E1E24EE8320" modified="2024-05-29" version="1" fragment="single">MSYQPRIVPFQNQAEFELIYKNLYSNSEVNKTFAVSRINVWRTRGRLPHSIDSTSYLTESLLSLKDGNLSKNQKCLQLSMSFIRFLNGLVDSKQKSFFAQSLSSIANEIGLPSWFVELRHTATHDKLPNLEILKNGCESALNWLDLNYWKLQFFEEYDVEGELEFKNLLIVNLKRYKDLRKVEVESGMEMLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVC1</accession>
    <name>A0AAD5XVC1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_000774</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010001199">
        <property type="protein sequence ID" value="KAJ3205493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVC1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004868">
        <property type="entry name" value="DNA-dir_DNA_pol_B_mt/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03175">
        <property type="entry name" value="DNA_pol_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B mitochondria/virus" evidence="10">
        <location>
            <begin position="475"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3205493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1013" mass="118967" checksum="151E1F36D36B7CB7" modified="2024-05-29" version="1">MQRIRRVSESIFGVDRLDYTQNISYDVWMRATPRQRELAIFEAYDKLVDISPILRVDYLPDNSDSIQQIFFLSESMNSLRIEQQKQNVLLESIANRQERSTEYGGWSPNETFENVIPDVHGDGFTMFVLEEEAFYTRYAFEPTFGDEQGYFDSLNSLFNSNIFDPQSFDSINVIFQVYNPDTNRNESYTFSSKMGVEYMMEQLYRLFCEENEGSDRYIFIRKNMFRVIITTIKIPSGGGKNSYVELCYKLYKPRLNTKLEDICFYTCIKIILKDIIGASHKGRYENLKRRMYPDDHSDNYSVPLNDLNIAAKVFDISFIVFENVEPEIICNNGTYTHMWKLYYPCEKLYASDIAIESISNDAGYIVINGQRYYMILYHNNHYDIIQKLMYRHCCSVCGSLEHVTGKCSSLEETTYLIAKQKVFYIFFDFETFVVGEQYPYMVAYIVTDISFSVVEQDVIEGYDCHYKFINKILNKYRNDMKYLIGYNNSGFDNYIIFKPLVKYNIDDDISDKNSIKHNNRLLRIVVKNLVIWDLYMFTRSSLKEACVNYRINIAKQYIDHAYISKMFEKFEHTTDIFRSDEYKSLDIKNYCMNDVHLTVQLFRKIYNELYNITKLNILNYSTLSSLVYKHAKLSFVKLPEWTSEIFNSIPGGRTQAFTKGVLKGKYNMLDINSCYPYICITNVFGTGECYYTKEYSGKSLYLCNCDVDQSSLKIKLIGYKRDKLTPLSWTENFCYNVWLQPEEIYALEANNCPIQVHGYIVWEKYNYILKDVMENYRNHRFQGAKELNVVKEKIAKLMGNSLAGKCMEKNHDDVWCVTKYQSKIKSYIEKYGDTVDIYKVSNKRFLVSGKKQPRNVLDKPRHIGSRILSLARLELWKYLSILENPIYCDTDGFIVSDTELEKFQMTDDKSYGLLKLETSSQETIIISPKSYYMSLDKKSLKGYHDGNIWEAKDNGKVVKTGNTRSKDLYECLLDSELTVTTNFDMITKRFILNKDNKYTLTVLKTIHTEKILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVW0</accession>
    <name>A0AAD5XVW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_001658</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001499">
        <property type="protein sequence ID" value="KAJ3202937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVW0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000094">
        <property type="entry name" value="Zinc finger protein 605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="420"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="486"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="375"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3202937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="567" mass="63821" checksum="A510AEDC3DED303C" modified="2024-05-29" version="1">MITSVENEFSVKTLEQNYNLANYQNYNQNDNFKSTQIKKGSELLNITSTNPTMNENQNIVDITTEFLLNQFLSSPQTGLTDTWTGINESALQQTNQRDPLYATLNKPLPVNFKPVQEAQTMKEQNVLFSPPKSLLNQPSKSCVGFTQIRQSVNSSPATNLINSPCQQVSPYFSTPTQQQQGFESLARSPQFPIDPRMRRNSVNMSVNNLVHNFNQNLQVRTPQQNLLLSPVRPLIVNGSSPLIGTAGNLFSPPQQPLYSPFIQYMNTPEIFAIPSPSPFLQALSSPNFNVNTNGGVGGINVEEDSLQGLFDFIMEDNTDDTSGVDILKDFQNESHHKNSFDANSFGIDFNPSNNITYNSEISDISNLNTCLQQKQKKPSKVKVKAPKNSNNYTTARSSMPPPIKMENAPGPDGVIREVLYACPHADCKDGNGKYIKTFTRPYNLKSHYKSAHTLERPYECEECGQTFVRKHDLKRHSNLHQGERPFKCPVCFKSFARADALTRHRKSVEGKMSLCDIKYDGKESDDCNIDLGQFFFNENPNVGLEFNQGGEFELEELFNVKQEFEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWG0</accession>
    <name>A0AAD5XWG0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001957">
        <property type="protein sequence ID" value="KAJ3200173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWG0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031537">
        <property type="entry name" value="DUF5092"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17010">
        <property type="entry name" value="DUF5092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="110" mass="12890" checksum="A4FF19152E8EF501" modified="2024-05-29" version="1" fragment="single">LKKKANYQEDNNSSSPKKSTNIKKNNPEVEEVVDLLDANNEDPFTLETLESLISLHWEKEKDFLLSRVTTVDPNNEEKFYRSYYAAHHINKVLFRTQPSEGLLHRMRAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWP3</accession>
    <name>A0AAD5XWP3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000182">
        <property type="protein sequence ID" value="KAJ3222285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWP3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041993797" evidence="2">
        <location>
            <begin position="19"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="180" mass="21187" checksum="8C6E76DCD1F11F05" modified="2024-05-29" version="1">MKLLFVLTLLIALAMVASRSYGHKHRHHKKHYKKHYANPEEVEADEVATLNAGEIEVNPAVNDDKLNEQNVQAFDDDDDDDDDDDDDEDDDSGAYGVQASYGYGHKRKHYGYKKHHHKHHKYGYKKKHYKSYLDAENADEDDDDDEGGDDEQELQSQGASYDKYKRKKYKYKYKKRKDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWX7</accession>
    <name>A0AAD5XWX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Radial spoke head protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RSPH3</name>
        <name evidence="11" type="ORF">HK099_001969</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flagellar radial spoke RSP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000161">
        <property type="protein sequence ID" value="KAJ3222754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWX7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009290">
        <property type="entry name" value="Radial_spoke_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21648">
        <property type="entry name" value="FLAGELLAR RADIAL SPOKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21648:SF0">
        <property type="entry name" value="RADIAL SPOKE HEAD PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06098">
        <property type="entry name" value="Radial_spoke_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="223"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3222754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="355" mass="41356" checksum="E125131940DF66BB" modified="2024-05-29" version="1">MLQYQNPPLPIQKSQTQVETNTHYDPNQTQHTGAENYTFSSEPRPLQENLNSSQKKKLYRDPIGYQNAENENEVGKNPPVNIMYDRRIHRGNTYASPILPLHAQQDPIALQSQQTQKRRQKAKRKADQSRRLLTPEPVEGRKHIDIQTDLYLEELSDKIPEAIAATQTDAFLDRAPSPLYIPQKSGVDVFTQVYEGELFDFDVEVQPILEVLVGKTVEQALMEVMEEEELDMLKRRQAEYEERRNAELAEVQRLEDAERRRTEEKERRLAEQVRILREKQELQEKITSRAFAISYLQKLVPSVFESLTTNGYFYDLVEKEVETLFLPWLTSEVELKLEKLIISQKVVDGMLKISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX36</accession>
    <name>A0AAD5XX36_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001514</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000143">
        <property type="protein sequence ID" value="KAJ3223113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX36"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="143" mass="16572" checksum="0771BBD5C56E9EA4" modified="2024-05-29" version="1">MLAQFGRHKIIREVLFTTDLNPTAENCSAMLLSTGSEETSKLLLQDERINPMEIGAELRKFKAETLKLLLMDERVDPSMNNNLLFQESCRFGNLQICKLLLQNENVDPSAHNNWALKVAKKFHRYRIEELLLTDQRVLDRITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX76</accession>
    <name>A0AAD5XX76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000497">
        <property type="protein sequence ID" value="KAJ3216126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX76"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="175" mass="20093" checksum="D30442555209EE76" modified="2024-05-29" version="1" fragment="single">NMAEIITHRGSSLNAEATQQMYHPLGMAITKLVTGELERWDEFLQQALFTLRRTTSRASFSSLSEKEFEEQRLQRNAQTFEELGHQRQRSKAQAVKMKDVHDNKHDSCNTNFAEGDWVKLIITVKVSWSKNRSFGTIPVPAPKNTFQIKVPGRELSVSKSFEDKTQSRELLLKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX85</accession>
    <name>A0AAD5XX85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 8">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_007919</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 8"/>
    <dbReference type="EMBL" id="JADGJW010000812">
        <property type="protein sequence ID" value="KAJ3211816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX85"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00883">
        <property type="entry name" value="beta_CA_cladeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF76">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601765-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3211816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="333" mass="37842" checksum="48F6DD6B5AE7A31C" modified="2024-05-29" version="1" fragment="single">MSDTEKIKEKSKKVNIELTKKVTHDLDELVLDDSEMSLEHLKGTLTAQDLWELKNNVIISKSHGDLPSTETDKDEISNEDAEYRKLKFGKSEGNISKRKSFAFEWLQKQNEVTPLSTPIDLTHSDNNLNESMSEKKYTGLSTFKNLKNLLAKNKLWAEAMVTADANFFKRLSLQQIPKLLWIGCADSRVAANQIVSLQPGEIFVHRNIANVVLNSDVNCLAVLQYAIEVLKVEHIMVICIYLLKLRTICKVVGHYGCGGVQYSMNSCLDLSVIDIWLRTLRDLYDDHKESFESLKTQEEKRDLLCELNVSNSVLAVCRSSIAQKAWKQGQKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXH9</accession>
    <name>A0AAD5XXH9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000182</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000103">
        <property type="protein sequence ID" value="KAJ3224132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="17"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="485" mass="53328" checksum="A796B7F811FE17B1" modified="2024-05-29" version="1">MLPENDSASTSFYLYLCTFVSLLVGFQFGFNSGVINQPRKAITKCTQPDSGIFVNCIPMDDLFNGVIGGLIGGFLAAKYGRKAVLIYNNLFFIIGGLFLSLGNEVVWLCVGRVLLGIGSGIGTVVLPTYISELAPNAYRGMFGTFNQLSIVVGVFTSLTIGIPLSTPEYWRILFSLTLVPSLFQILLMPYCTETPKWLASRGRIYDAREALVALRGSNDIEEELEEILLISGNVLESPSQHFEEGIFANDNNNNITSPIRSQINNTGIQWPLSTLEMFQCKALRRVLISAFSLQFAQQFSGINVATFYSTTIFENSYSPETAIKLTPLLSIIIMIGTIISLFLIEKLGRKSLLITSMTGMSISSFLIALPVEQLPSLIVCYFIVFTFFFALGLGSIPWLILPELIPVYALGPASGIATAINWGGSFIIALFSPVLISVMGYQLFFIFTVILVLMIVLTYFVIPETKGKTAEELVGYYVPVDEGHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXP2</accession>
    <name>A0AAD5XXP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000406">
        <property type="protein sequence ID" value="KAJ3217880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXP2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF13">
        <property type="entry name" value="OS03G0201400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="68906" checksum="5CA4D5B0DE6246F0" modified="2024-05-29" version="1">MLDEGCFEIQNWKLVEEYYETLLAMGSKISPSYNDFENYNEMILKAWCNLNKLDKAVEYVQNLPTQQQGLTTDQIVFLVNLLSKELLEKGETEKAVKLCEHFKSNAEFKPHPETVLVMIKSYCESDNITTALATIVDFSLRYSTGKKSMEILKMESEMYKFLFMSACKKLDGAFIDEILISMKRDDILVTSEILNILIEYYIKQDLIDDALKVYLSFKFESQERLREATADLDNAHNIQSLKQELKIPVSVYNYILAGLASHFRMLEFRELWNELKDLNLATSGTYLLVLESYLHVADVSSAFEVCQHLMDDITLEKPNVKLILKLLDATITSGKHKETAQVIRWIRLVSKKSEEEQINLEAVKNLKTKVLPITQLMEKFILEGLPEKFTNTKPLVETNDKLRTALDIYEELLKLDVSLPYSLYTAFIKHYHLRVKDMVGVARTWTSAVKQSKLQGQHALPAELVASFLHASKDLCLKQTASHVLKFVYTENIVLNKISYEHILFIASKFGWLDIVTDFLEKMENDGIKVDSNIFDFCFKNLKNFHSDANSTGKKKAIINQSKLFEKYMEKNFPEAIGSWYDISDNQLINEMKRLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY02</accession>
    <name>A0AAD5XY02_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008276</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000899">
        <property type="protein sequence ID" value="KAJ3210267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY02"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3210267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="60897" checksum="70B7DA32C47F3E45" modified="2024-05-29" version="1">MENLLIRANIKSSKLIEILCSKSYLKLSLLSFTSIYFLTKLLNFTKEKIRLRNKKLPPVKKGNFLTKNFFEARKYVMEDNFHLFIKNLNEEHSITRFEVPVFVKGVSVSDASAAKDILCDTNRFNRAEVLGDQVFEGLIKKALFMLNGNLHKKHRKMLQPGFSPSHLKIAFETSKECCHRLFKAFKMKNIKEIDVYDYFKYISIDVIGKTVFSYDFQLTKDLDIETSKYDSLRQLEKMNVALQKRALPRFLWRYYGITVSQMEKEAKGIQDTVTKVIEHKKEKLQNREPSSIVGKWGMDVLDRLLENSSEIGEDKEKPFTTEELRDEVLGFYFAGLGTTTDSLSLAVLDIFSNPRVVKKLREEVDEAFNKKDGFTYENLNNMKYIDCVIKECQRLHPIALLLLKQAVSDTELHGYFIKKNTLMVINVISMHTDVKYWGADAEEFKPERWRNGFVPVPGSYIPFSDGGMNCIAQKLAIIEMKVVLAEMIRTYDINLVPEQDLRCVVIDGRVGPRNGIKIYFEERNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY93</accession>
    <name>A0AAD5XY93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000550">
        <property type="protein sequence ID" value="KAJ3215355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY93"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="228" mass="26420" checksum="5D952B5099AE6CA5" modified="2024-05-29" version="1">MSSIDQVLSTTIDLIHLKNTKNIMVSTDINNLNSKIAKEIDYYNRKIEKLKTEKEKIELDGGTVLNDLDKLILTLNDLIKIKPKVLAEKKKELLNKEPKNKNNVLKNKGDKYEAENENGYKENFYYNLSNKSIYIKEISQEEFNTLPLTLSKYNFHFSKLTNLIGKMGLERVNNGVRKLTKGLVRFQRCLEELKEDEDGRKVYQGSAVYAEEGAFYVRKEDLLGKCQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYF6</accession>
    <name>A0AAD5XYF6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Large ribosomal subunit protein uL10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">60S acidic ribosomal protein P0</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RPP0</name>
        <name evidence="14" type="ORF">HK099_006398</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000055">
        <property type="protein sequence ID" value="KAJ3225677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYF6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 14" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="735"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="778"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="831"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="864"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="899"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="928"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="13">
        <location>
            <begin position="108"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="648"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1049"/>
            <end position="1069"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00035444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1069" mass="118730" checksum="03978791C0A6EA29" modified="2024-05-29" version="1">MSKGEKKAAYFTKLESYLQEYSTIFIVNVDNVGSNQMHQIRQKLRGTGVILMGKNTMVRKVLRGLVAENPQYEKLMPVVKGNVGFVFTKGDLKTVRKTITENRVRAPAKSGALAPIDVMVPAGNTGQPPDKTSFFQALGVPTKISRGTIEIVNDVHLIKAGTKVGSSEAALLNMLNISPFTYGLSIRHVYDDGAVFDPVVLDVEESTMVENLMTGIKTVAAISLALGFPTVAMVPHSLINGYKKVLGFALGSENYSFPLADKLKDLLSNPEALAALSAAAAAPAAGAGDAKKEEAKVEEEEEDSDEGICFYLSDGHGEVSTIPVSLRMTRVWRGSKGENFMNLIKKVLPRLVLWGKIYFCNIGDSSMTMFNDMNDKPLKIWKKGGQSEYNHCSFEDTLANFPKSLREGQTMESVKLDFETLEKYLKKSLLPNLKVPSYRVVSNRSMYGLGMTNTIGNLNHKGSLVGENGLGRTTIYEFDDKLFEGNGDELLILFCSDGVKDVLDSTDFASLINNLEKGLISLAKKYSTEEIDEFEPMEDILKKISTNGSEFEKEKYMNEEIEKYDELNLDKFSLESLNLIMEMVLSNEEKKNWSSLKEICQVFVNLAVLKNSFDDLTCFLLKIKKCDLIFTAEDPSEFNFCDVSFFNGYLMEKIFWKVIGFTWYESLLIAACCAPTDPILANSIVNGRFAELHIHPRVRQLLSAESASNDGCVFPLFQLAYFLMKFSMAEAFLHWSYATILYEIIGAAILGAIIGYVSRISLRSSEKNNWIDKKNFLVFELALAMFTSGTVTMLGMSSFVAVLVTGTVFAWDGWFAEETHDAHVQEVLDMLVNIVFIPFQNEVFFIFFGSIIPWNAYGTAELPYWILITAAVLILIVRRLPAVLLMMRFMTPLLSFSEAFFVGWFGPVGVGALWYQTRGSILFPDNKLFGPVVAFIVFSSVICHGIMVPFVHLTIVGIRYTSTQSRTLSQTSRGRGIAPTWPTGVAMSAGVISSPEPLVRTADGRYIPASSICLKNTESLVLFEKEFQNKETDLEPKLIPFNEQSSEEIQVGASDSTLDGIADSQNDLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYL7</accession>
    <name>A0AAD5XYL7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome b5 domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CYB5D1</name>
        <name evidence="11" type="ORF">HK099_005728</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Radial spoke stalk protein that binds heme under oxidizing conditions. Required for the coordinated beating of multiple cilia maybe by functioning in a redox signaling pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYL7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052320">
        <property type="entry name" value="Cytochrome_b5_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21281">
        <property type="entry name" value="CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21281:SF0">
        <property type="entry name" value="CYTOCHROME B5 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="10">
        <location>
            <begin position="57"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3226022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="270" mass="30801" checksum="9CCF5486169ECD35" modified="2024-05-29" version="1">MPPNDDREVHTAESNKSCISENSKLLQQFPEKASAVTSTSARNYKSLVAKKDIKVNEIFYSRNEVALHNSPDDLWLSWLGYVYDLTELSQEYNDDPLLTPILRNAGTDISHWFNPLTGDLKTHINPLTGCECPYTPEGRFLHVPPPLPRSDWNSSELDQTPWWLEKSYCIGTLSKKTRFLKIINTLTKDEHTIEVCSEEKITAIQDRYTSLNAHAKGYMWKRLGVLLDMNATLEQNGVVDSSNVFEEIGLSEDDWYPAIHLFFSDDLTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ27</accession>
    <name>A0AAD5XZ27_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000400">
        <property type="protein sequence ID" value="KAJ3218009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ27"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="580" mass="67433" checksum="0A5E8294BB16528F" modified="2024-05-29" version="1">MNNVNKENLPYIIIGSTVLLISTLFIGNHVINKPKRKRNTIHIDFDLSKPKLNSFQIPFELNPDIVRKVCQNIINSNLIESDVEDSEEEEEEEGKYKKVVKNIDEIKDESLLKIENKILKNKNLKNFFKIEEKNKKFNNNENSIKFLPEFPEQVAHLLEDFRLSKMERRVLLLEGAPGIGKGTALQQWVELESKERIAKYLRLSTLFGLKHGQSSQENLDDEKEDKEKWRKALENSLGFDKKYFKKKKNDNENNENEDNFNNFEKFGGKSEFINSSFAYISQALTILRENLQRPPLLVIDDVQLLFKKHSVLEEKYNDISETFQWLLNCQIKDLLDVVLCSSEKSVLTALRNIRGFEYNLKFKAVESVDDEVIIKYLLTKVNPLLEKKTPQNLSTGNKFTIDTARLFVSTFDGNMQELENYCKSGKSIQEYINFREDEIFLQLSNSENSLLPEGVTESELKETILDMILRNGVLNVSKLSLNQLKVIELLVEGNFFRWRNGKVKKREALNKAGAGGGAEELLKKEVQEIKKNQRKLRVVSSIEELEFSNPLAMFNREEAELVWYNPLLGRVFEKWWNLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZJ8</accession>
    <name>A0AAD5XZJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001796</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000155">
        <property type="protein sequence ID" value="KAJ3222872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZJ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF2">
        <property type="entry name" value="MANNOSYLTRANSFERASE KTR5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR018153-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="404" mass="48681" checksum="CA3FF01A31CD7EF1" modified="2024-05-29" version="1">MLLSRRRMLMRLTFYICIILFFYQLYEKIPVGKQEKISLSEILKNERCKKRTCVKCPLRPTTVPSFRVNAAITILCRNEDLEGIKRSLDSFDRNINENLNYPYIFINNVNFSETFKNGVQNHLLMLREKSLNIPIVEYSLIDEKDWGYPEFIDKKKAENVRKSFKSRFISYGRLESYSGPFFMNKDLLKYDYYWRVEPDVDFYCKIDYDPFSLMKEKKFKYGFNMMVKEEMGTIPTLFKTTMDFLKFNNIKPKSLFKMFMVKKNFFLRLFSKEKFYYNGHHFWSNFEIGDFKFFRSKPYQDYFNYLDKSGGFFYERWGDAPVHSLAVGAFLDKNEVHHFSDIGYRHDIAENCPIFPPGKDCGLKCNCVQRPNWMLPFGKGIYSSYWNKIYTWYDFVDEEEELHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZP8</accession>
    <name>A0AAD5XZP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Gamma-tubulin complex component 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TUBGCP3</name>
        <name evidence="10" type="ORF">HK099_004266</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BLOC1S2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000299">
        <property type="protein sequence ID" value="KAJ3220475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZP8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019269">
        <property type="entry name" value="BLOC1_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF14">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10046">
        <property type="entry name" value="BLOC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="9">
        <location>
            <begin position="163"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="8">
        <location>
            <begin position="429"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="866"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="904" mass="105087" checksum="4391826D2B0AEF88" modified="2024-05-29" version="1">MMGDEVENNKIFLDLEEQNSILVQRLLELHSKTNSENFTKYCIRLLNSRFLPKNINFEDFKISISNINKSLLNLVSKLDKSSVNVLTFLLSLSKVDKSIANTPNFYFLNSLNKQTKINDVLKPLKRNESQNGVQNEVTDCKHNKATISTPFHNQLPSSEIISAMLYSFIGVDSSKIKENNIIGDLSTPVKLVICDLLQMSTTYKILKNFCDSKTENEGIIYQSLKAQISSQLNEYYRLIAVLEQNNKTEELSLRRLLVWTKQPLLRLQILLNYCDLIKTHRGGAFLSKLYRHRLHGNPVVSELSLIVLDNVSKPFFEMIKSWMYHGVVDDSNEEFFISVDLTLGVEEFWKNRDCVRNNMVPCFFSESLVKKSLNFIRYVCSDKTFSIQTLKNDAVFSYGKLLELTVFVEKVYKKTNKRLLELIYGKYKLFENLLALKKYLLLGQGDFIQHLLVDLESNLSKSAKLLFRHNLTGTLESAIRSSNAQYEDPDILSKLDIELSVMKSPVESGWDSFCLKYQLDSPLNTIITKSCMKVYTKLFLFLWKVKRVELSLNKSWCLNMRNRRSSNIEVEKHLHKCKLVCSEMIHFVYQLQYYFQCEVIESSWLELKTLMSRNVNGDYDYDYSMLIKIHSEVYLKSLVEKGLQGNKHRDILKKLKIIFDCILEFKIAHENLYHWCSEQVENGMEIEKFEYMNTLTSKFDSQIKENEHKMDNLNNSQENHSILKLSLISKQFRNEIHGLLNLLAIDQDINLREQRMNHSHQIDSNEDIFSSFPSLSPTPSLSSLITSENLNRKVALDLATDAIQLVNRNTKLSVSNSLKDLVTLENLTINSKEKLSSLNEKATEFIECANELNEIYNETEVFIHDITELEKQVTNLEQVAKEVDNYSKTLEDYFKRNMELKKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y147</accession>
    <name>A0AAD5Y147_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000151">
        <property type="protein sequence ID" value="KAJ3222957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y147"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF95">
        <property type="entry name" value="F-BOX PROTEIN YLR352W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="636" mass="71848" checksum="53F4D9959AA7D01B" modified="2024-05-29" version="1">MSRNNVRGPTSALSSFLKERGITSSTVNYRTSNPLRRINSTDPPADAVEASADGETTNAGPSTSTSEQTTENGTTENLVQIPVRVPNKKKKRQIDSDDDEAFEKPIGRSNYSKRLKQKFDGEGVRFCKKCNRRYFNEDVAIEKCDACCLITNSNGGVEVKPRKKKKKEVGLLVERKEYGVKSLKDLCLQVVADYIEDVEDFGSYLTNESKVKISKIISRNRSLNNRTFKLFIGPDEDEVELFDCTRLDESALINIAQFCPMLVNLKLKLCGRITDKVIFEYAKSFRHLTSFTLSGCYLVSDTAFQNFFEHLGKNLNNVNIEDAAKITKKSVQVLLDNQMPQHNLRKLVFKRCCYIGEDAMQLAVFKIQECGGGLGANARTTFKERKLKLRKNIHEDEAGSNEDDDLKDEEVNGDEAETEQEAEASVENSQKENDNLKKAQQRSITGDDQPSDDTIIKILEANGNTLTELSLEGFIFMEDKVLLEGILKFCPNLLKLSLARNENLTSEGLKTFFQEYQKPIGNLVELNLKKLLSVNDDTLNCIVNIHQQSLVRLNLYGVEELTGDSLKSLANLLKLKDLDLSWCRNIDDEMFKDICGGMNYLKIVKIFGCHLLSESLLDREWKNSEGFLKILGSEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1L4</accession>
    <name>A0AAD5Y1L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000112">
        <property type="protein sequence ID" value="KAJ3223917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1L4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="841"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="847"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1048" mass="119009" checksum="2D1F8260074CC589" modified="2024-05-29" version="1">MSSYRCKCLWKDCTESFQTEMETYEHCYKSHALNGKQSCLWISNINRGPCLIKITHKGQVKDHLITHFSSELKPIQCLICSKRLRNRQELNKHKKINHNSASSIHTSLHTDSNITLCSFNYNSSSENTLDIVEYESPTNLSPSISLSTFDPNKTITFNNQENSRLDLLVKSSSSTFNKINFNTTDNNTSWLIGPCCGIFYEIIDLVANRFNIKIPDTLKLSVLTTYKIGGVNGRIPPNCKLDFQNLLFNANFTLGEVISYGSSILPMAVSKFIIPEFKTTLFQELNLELEKLYQESSNTNVSTYFSDNNLKTPPLKRILNVIVKVFKTAIEENLSNEDNFFFFEPTKKSKLFLSPSDCSGSTVILKRSKVSILTTKTMEKMSYTFLGDIFNTEINNILRLIFVKEVNFRNLCCFGLICRGEIKFNSNFFDFQDEKNFSQVGAFFRLGVNDDFVYRMGEVAVDSSLFGTSTPVSLLRNTKCFKYVIDSVTKSGQAKALLIDPLNSNNNGSTNASIKNLFFYSFSTAVSIPFVLSGITLNSSSLSISAGAYYRSFINSCAEGWNSIFSELSFLIENNIDLIFILDSDKLSIQKKATYFQRHKKERKLLRRIKNLEKSKKCKRKALISIKKLETLLSKFKSVDKNKIKEAFPKDAPLNCSLQVADFEADVWIGHKGKKDNQRIVISNDSDLLVYENTKILIRPMAAEFFIINKESFLEKLDLTIKKFIWVCSLCGNDYSKNVYKKGIATVIKTVKKCNSFNEAVSDLTRGAENAEDLTNNFQSAHEIFTLGNEIEFDLKTMTKNPKLKKKKDTVPNIIYESRGFTYLQDAISNENPVAIQRPINIPQRKRLSDRAHQPGRKERKKVVVAENRADSAGPSTQPPLRKKSESTAQLNELKKKHPYFTITTGLRSSLKRAFPGDNESYKSFEYGIKTAISALHQATIRCNIAVGLLIKHYTENNNPDPLKTLIYGSTATANGTLFFQQMLKAVWSGKKIENMLPEVQKGFELLVENMPGETFRPLETKLTNMRRLIEIRAKELDTELSNLDGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y229</accession>
    <name>A0AAD5Y229_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000080">
        <property type="protein sequence ID" value="KAJ3224813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y229"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="43919" checksum="DAB32276F5784C25" modified="2024-05-29" version="1">MASRPFDNENEVTEHYYPELYMPQQKNQKQAGAYQQYYTNQIYSNYNHHPFFVSEQPFSSNFQPLLKPSFGNEQIYLPTPLSYSNNSGNSKYANNRYQALEHSAAANYIVRPVNYLDDVNKRKRSDASDIELINQKSRLKNGKLRIGKLQKKTTNRYCCGCFGHRRSCCCFWLWFLIAILAGLGAAVFLLFPRLPDIQVNTPYINTNEPENFKTSGSVLDTSPDTPFTFTFKLYLDISVKSANYIDWDLKKVDVEGKLQNLDDSVNKNIVGKGTKENVKIKKFSTTNLTMPIEISYFFNEKITNALNDPGMQLILSNCAFIPGTEKKDFKLSYQVLIDFPLVSWTGYTPTISGITNFPCPISETDFTSRFGPLIGMVFNDKNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2F0</accession>
    <name>A0AAD5Y2F0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Aminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_008505</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000094">
        <property type="protein sequence ID" value="KAJ3224400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2F0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09603">
        <property type="entry name" value="M1_APN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF299">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="10">
        <location>
            <begin position="43"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="9">
        <location>
            <begin position="280"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="903"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="903"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3224400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="945" mass="108766" checksum="23A4EF781FA22065" modified="2024-05-29" version="1">MVKLLENGGCFCKHNLLQSKSIFSGNFCGDGKAHYAPNIIIQPIHMELHLDFSEIKNCTVKGKNFITFTHEISTNFFLPQQKDLTTVYLDAISFNDLTVKGEGTRYYYDGRKLTICWDSPFEVNENRKVEIDYTVIHPIAGIYFNIPNEQYPMRVMHCITDHEPERCRYWIPLVDSPTVRTTLEFLITAPTDLMAIANGRQTMKKKIDNDLSLTKWVLDTDRCPSYLICVAIGDFLYVEDNDPELNIPISYLGPKGKFSKLDFSILFTGKQKAEDLKRTFGKTASMIKWIQKKLDYPFPWKKYYQIVSPQVRGAMENISFVAWNDFYCIDETLSKEKQLLVDQTNVHEISHTYFGNLLVVRHFDHTWLKESWATYMEAVWIEEHLDADHFRYEMLDCKHLYVQEAARYVRPLVKRVWESPWEMFDSHAYPGGGLRLHMLRMLLGEHAFWAGVRNYVKTFAGKVVETEDFRKCLERSSGLNLVKFFDQWIFGKGYPKLKLKFDYNFEKNIVQIKLEQTQSSKDTGVVKIFEINFEIEVEDINGYVYSLNLEFSDSTVSSAQVALMDTSTAIKIIRLDPLGKLIFDVETEGSVPEVVLINTCKSAKDICNRIWAYEELINMGTTNGMRKVQENILIEPFWGVRVQVANALSKAKTHLCVLTLAAMLENEKDFRAMYGLASACNIRDPIIHNALRKFLNNDNNPYRATAAALENLGKQNCPADLEYLINFANDDTKIGQHGILRSGVFEGLANHSSKGSYVYLEQQTRVSLFPALRKESEKSLKFQPEKTLPALISGLATAALKQVCNASQNHVISLLTDLLRDHRHFVKKEAILALCEFGNVESIPAILGTKPTFADQVLLDWMFIRRMLSSLKENRGESKIKDLVRNLEDVEGRLRKMEWNWTDDKDSKQRDEEEAENVKKETDLGGSIRNINNNTRERIYECTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3A2</accession>
    <name>A0AAD5Y3A2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002923</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3A2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="279" mass="31327" checksum="CC87754A54EA7FD0" modified="2024-05-29" version="1">MKSNYFKGFTLFNTSKKKSKNSILSDVETMNDAKENMTKESEMPIATHAVFKRSAGSMTCDEFAKACGIVVLEEENEDLVDDLTSECSDPNALTSTSSNFYNTTSNLSFSNTDTQLSPRRRRPSLGSILNADIFVPPNNSIPSSNNSSILLDQNEISTIPEQVDVLPISEQTDFTSNKSFTQRLFSRKTDATLAVSNDQQQLETVVEKKGRFLVTNLNKSALSKRKFSIINYLPSSSFENTNGFQKPLSSETDTFNLNREKLKYRKVPIIKINSKDVFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3E3</accession>
    <name>A0AAD5Y3E3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001926</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3E3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009851">
        <property type="entry name" value="Mod_r"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678:SF2">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07200">
        <property type="entry name" value="Mod_r"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="UBC core" evidence="7">
        <location>
            <begin position="39"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="VPS37 C-terminal" evidence="8">
        <location>
            <begin position="131"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="162"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="281" mass="32602" checksum="2EBF711ABA8EC04B" modified="2024-05-29" version="1">MANSSPFLELKNKQISTLFKEIPTLEQIELNSSYKVKLKNSHFYLVISLPTNFPQSSPILSLNPSQTAFHEMIDQCGHIKSQKLNNGWRQHYSLGKTCAEILTLLNQNPPTLNISLQQQIAIETNNPANNSIEELEELILDDNAFKVYFNDITQVKNLKFSRDEIQIQNETLSKENLEKEENLTRIKNNMLSLMEEYSIARAEYASVFDELLKAQERFSNDSMISILKKHIETYESSSELLQAKYFELKDSNLNADDFLKSFLEDRKNFHLYTSKLDNFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSK1</accession>
    <name>A0AAD5TSK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002081">
        <property type="protein sequence ID" value="KAJ3199588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSK1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="272" mass="32075" checksum="0A5A23F9F6D13ED7" modified="2024-05-29" version="1" fragment="single">MESFKPLPEDLLDTDTACKYCGISYLLLNKYEKTKLHVENLELKLSQLQEFANERPTMLSRMEILNEQQKTQSLTINDLNLQLTNNKSLLQENLKTLQNSETFYNNYKSETEIKIVNLKKNKNLLESKLNFLNKNLQKIFNQLRFERLSIDQCNKAFLLEIQNTKSSFKQVELDIKKQVEKHFILKKSESNLNLQNQINLTLDKESKKFKLIEKEKLDLNLTLNKKIDDLNLKLLQSTEITKVDIMKEKETSNNLKKEVKSMDIKILKLKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTF9</accession>
    <name>A0AAD5TTF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001613">
        <property type="protein sequence ID" value="KAJ3202159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTF9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="117" mass="13490" checksum="D9F4695CC687C321" modified="2024-05-29" version="1" fragment="single">MFLKVIYQKKCFDIQRPVGVINCRNAKMDNENEFFTNLQKPGESKYLTLPSSGGPDISYSYFQCDVKNTSAAESTIKKFMKSKECEKNLDSLNPNACYENWPPSKRNCEEILKEIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTI8</accession>
    <name>A0AAD5TTI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002372</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001780">
        <property type="protein sequence ID" value="KAJ3201117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF27">
        <property type="entry name" value="TRANSCRIPTION FACTOR AP-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="190"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="144"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3201117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="266" mass="29484" checksum="D346FFB8D98150F0" modified="2024-05-29" version="1">MIFDSDGDEFFKTGIFSDCEISEFDSFLNTVSNESLASNSETSPPFQTTGTCNSLSMLNDSLSVLGDSPPSVKDSPTHFSDCSVVSSDSISHSDSGLESPYSSITYLPSPPSEFLQYTPMFLPTKDTHLTMSSVVSLDATHSLYSTRPNTTSSTKRKRSNSMKSANDLQPQQYPRLKILKPPKDLLTEKQKKSNHIVSEKKRRSNIKAGFDQLTDLVPELSNGVHRSEAEILKICAEYIEELLEQQQDLNLQLASNSIIKMTALKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTS4</accession>
    <name>A0AAD5TTS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001424">
        <property type="protein sequence ID" value="KAJ3203469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="138" mass="16053" checksum="753C7A528C9FB0DC" modified="2024-05-29" version="1" fragment="single">SFENSISEYFLTKTDIKSNKDTESTIYSIPEEISIPTLSHQNQIEEEKKIIQENDDNFFKLNNIEKINSIKSFISEWYLNSEALKVDVKQDLVKNTFESQDSLGNLSETSDIQFDIQIAEHRRTKYNSVYSDISISKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU24</accession>
    <name>A0AAD5TU24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001408">
        <property type="protein sequence ID" value="KAJ3203589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU24"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02989">
        <property type="entry name" value="Phd_like_TxnDC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21148">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="65"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="22738" checksum="B761053072CD038C" modified="2024-05-29" version="1">MAAIDEEEEAILRELELEDDDFSSKFRENRAKELKTSIDSYKEMKLNKFGVLSEPDNEGELIKLTSKSKYALISFYHEEFRRCHIMNGHLEELAKKYFNTKFMKFQVKNAPFLVEKLKIQVLPCVVMFIDGQTVDKIIGFEELGETDNFKIDVLEKRLIKSNAIQDDTIKDGNRPNTIFGFADTKRNDESDEDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUD4</accession>
    <name>A0AAD5TUD4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADP-ribosylation factor-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARL1</name>
        <name evidence="10" type="ORF">HK099_000829</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001205">
        <property type="protein sequence ID" value="KAJ3205423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUD4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04151">
        <property type="entry name" value="Arl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000306">
        <property type="entry name" value="ADP-ribosylation factor-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3205423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="173" mass="19432" checksum="C0132102255B81B9" modified="2024-05-29" version="1" fragment="single">MGLIFSKLFSSLFGQKEVRILILGLDGAGKTTILYRLQIGEVVTTIPTIGFNVETVTYKNIKFQVWDLGGQTSIRPYWRCYFANTDAIIYVVDSSDHDRLSTSGDELKAMLEEEELKDAILLVLANKQDMEGAMSHTEISEKMGLTELRNRQWTINKCSAKTGDGLNEGLDWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUP4</accession>
    <name>A0AAD5TUP4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001282">
        <property type="protein sequence ID" value="KAJ3204613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUP4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="287" mass="31949" checksum="89B0FEEAC54896CE" modified="2024-05-29" version="1" fragment="single">AFINCVSYWIAINKPPSEDPSSTTSIIFNAGIGVIWIIMVITSYWFLKNRFALLNVNGRSQLKILNAVFVVLLLVVFYTMPALMLNILGLRSAVETKWDEVVEVLICCICETVLAITFLVELSKQKSGNNLAKQTTVQIQRSVYLMLMLDLFAPIILFSLGPFYCYQMKTFSYGVKARLEMQLYDLIKKLFANRETLVGTSQLSSIEEKNFANTSALALKKYPGFTCNNCGKVHDDQDIAFSRQPLATSQASSGLGSVILGSKCSYLPPSSILNYSTSPLGENMHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUR3</accession>
    <name>A0AAD5TUR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000367</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001084">
        <property type="protein sequence ID" value="KAJ3207023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="240"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3207023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="329" mass="37655" checksum="E9504404A417D682" modified="2024-05-29" version="1">MPTSNLNNCNLDLQRILMPTNFANNLCFNFVFEQPTLDLNFELLIDSISQKSSPTDTVPSLLHVDTNFDLLRSSSLSPDIYDLTLPDTPFQTELSWQETLIESELSSSPESLLQSDLSSSPETLLQSKASFLPKTQLQSDLASLPETLLLTNLSQFTCLQQLPFNSAITSTFNVNLDPNIQNSQPSIPITIFPTNPSSFIDYEKNNQENLTLNHSPTVPSTNLTVKMNKLKSKRDLKSVYQCLHKNCGKVFKRKSNLKSHAVIHTQEKNFTCNFCHLKFLRKYDLKRHHSNIHFTYHLYSCSLCYNNFDSEKLYTDHYIDCSKINCKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV32</accession>
    <name>A0AAD5TV32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001107">
        <property type="protein sequence ID" value="KAJ3206686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV32"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="222"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3206686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="38396" checksum="E7EC7E46A62E5B19" modified="2024-05-29" version="1">MEKFEKMKLKESKVKVNLNNEIVELENSLNKLKDDLANLKGEEDRFDELPPDETILSSLQSLSAGASTANSLGQHHFINHLKASVQSPAQQKNSFHENILKQAEFQAVKSSSANSFDYKAVSNDRLPSSSINNKEGASEASAVDVNNAIKDGVKRQKSLKSENLDEETDDDDDQDAVDNNEKLKKENLKFFLPARPVEFSGLFDFSSIIRGEKVINEEVKKTYGPGYGNHEDDDIQDVDSTDESEDDNDSDSEDGDLQKFYFEDFNYDNGYDFKSEKEENKRYNHKNKYNGNKKHNRYSKNYYNHHNRYEHKNQKYNRKKENNRQKYSDYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV84</accession>
    <name>A0AAD5TV84_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002074</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001662">
        <property type="protein sequence ID" value="KAJ3201850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV84"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="423"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3201850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="529" mass="61333" checksum="BAE1998E5C7DC2A7" modified="2024-05-29" version="1" fragment="single">MQTSQFSPQQLVDHLQLTQSELNSFLDLLSSNKNLNNSEINKSIINLNLLFFQIHQMIKADKNNFTNFAKTKLNSINRSFNLFLSKESNLKNKSGISSYFDFFFNLKKFLTLFFDEKIKCKFENNLFNENLDFKNKKKFNLNFDQVETFKKKLNSKDNSDFSNFKKAVSFENDDHDDKNENFDFFFDKNFSFDHKSDFDIKDNSTTSTAPIIIPLSPDLDLISFENFNDLHESSIFFNDLNNNEILDMDFNNNNKLDQYLTPPEGETLLSKEIQQFLNASSQQLSPPVSIPSSPQEPLNFFSVDDLNLLTPSSSPQLLPENLFNNIEPMLIINDTTIENILNLDYNDNNIPNLDTSILDNNKNDTAITTTKKKTTTLNNFFNLNGELLNSKKIEKKIIKLKSKLFTKEKLALKKILKATKTTPTFTSSTTTPSKDLIQHEKESKNKTDGYDENSFVEIIKFSLENGKFNYACPICKSEEGDYSKVFTRPFNLKSHYISQHTDKREYGCSICNLKFVRRHDLQRHLKLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVL3</accession>
    <name>A0AAD5TVL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000966">
        <property type="protein sequence ID" value="KAJ3208985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="113"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3208985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="256" mass="28783" checksum="F7112C21EC741C24" modified="2024-05-29" version="1">MDLKSVTTSLQSGLKVLSSTKKRASKRSSLIRGHVPLTENIDHAKNTKASVATQGLLNARQKVKELVNTISKECRTKNVKFRDCDFDLQKDLNCIFSFDEEVDSAKFPAGVSRVTKIFDNPTFYRDGINHMDIKQGADGDCWFLSALAIASNIPRIIENLCVARDEEVGVYGFIFFRDNNWLPVIIDDQLYVGINSLESAPPILKAVFRGKDDMYQKVVGGSNTLHFSKCRDPNETWLPLLEKAFAKANGDYKYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW23</accession>
    <name>A0AAD5TW23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001253">
        <property type="protein sequence ID" value="KAJ3204912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW23"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="127" mass="14720" checksum="55BAB3AF9415A1C0" modified="2024-05-29" version="1" fragment="single">MLSTNLPDINFTSDIVFALELLNKLTNDVETFKSENQQLKETDNENFKFELSNLIQNQKILIKELISKVLKDIDEASKTISNLKCLDEGLTNLDENCKKKARDLKVKKNALERYRDVHAKKFDVMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWL3</accession>
    <name>A0AAD5TWL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Microfibrillar-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MFAP1</name>
        <name evidence="3" type="ORF">HK099_001192</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001311">
        <property type="protein sequence ID" value="KAJ3204346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033194">
        <property type="entry name" value="MFAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009730">
        <property type="entry name" value="MFAP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15327">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06991">
        <property type="entry name" value="MFAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Micro-fibrillar-associated protein 1 C-terminal" evidence="2">
        <location>
            <begin position="150"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="352" mass="42045" checksum="3D462366CFA27F99" modified="2024-05-29" version="1" fragment="single">MSNRKQRYWAGKVIAESESESEDSDSNASTKGVEEEERNVEKNTKSLENIKITNNNKPVKTPQSNNQKNEVLKKNTQNYTSSNKEVEEKNDNFLKVQDVEEEEVERRRRLKLRQMQKKREEEEQALKNQAAEESSEESEEETEDESEEESEEEEAPKALLKPVFISKAKREALAEQKKKELQNNDFEGEEAKRQKEILVRKKLSHRMVEDEIRREQADAEVKIAFEVDDTDGLNEEEELEQWRLREFTRIKRDRNEAQLREQERLDTERRRKMTDQEIMEENERLHGPVKEKQTLQFMQRYYHKGAFFMDDESEVLKKSYDQPTLEDKFNKELLPEVMQVKVSYIFANKRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWQ9</accession>
    <name>A0AAD5TWQ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="16">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">DUS4L</name>
        <name evidence="20" type="ORF">HK099_007518</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(20a) in tRNA + NAD(+) = uridine(20a) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53348"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.90"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53350"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>5,6-dihydrouridine(20a) in tRNA + NADP(+) = uridine(20a) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53344"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.90"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:53346"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(20b) in tRNA + NAD(+) = uridine(20b) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53352"/>
            <dbReference type="Rhea" id="RHEA-COMP:13537"/>
            <dbReference type="Rhea" id="RHEA-COMP:13538"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.90"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53354"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(20b) in tRNA + NADP(+) = uridine(20b) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53356"/>
            <dbReference type="Rhea" id="RHEA-COMP:13537"/>
            <dbReference type="Rhea" id="RHEA-COMP:13538"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.90"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53358"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="9">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 18">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the Dus family. Dus4 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="16"/>
    <dbReference type="EMBL" id="JADGJW010000734">
        <property type="protein sequence ID" value="KAJ3213211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWQ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102266">
        <property type="term" value="F:tRNA-dihydrouridine20a synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102267">
        <property type="term" value="F:tRNA-dihydrouridine20b synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000159">
        <property type="entry name" value="tRNA-dihydrouridine synthase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF31">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20A_20B) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 16 18" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="19">
        <location>
            <begin position="30"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="17">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="32"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="248"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00051779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00060741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3213211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="328" mass="36771" checksum="061DFC778A891B61" modified="2024-05-29" version="1">MDNNQTENEWAKRFSPLDLLTNTKSSLNICAPMVRYSKLPFRELVKQYGVDVLYTPMILADVFKNSAISREVDFQTSINDSPVIVQFGAANSKDLADASELVAKYCSGVDINCGCPQKWAISEGIGCHLMERPDLVADMISQTKRRTSILNFQSNSGTGFPCSVKIRKHNDLRRTVDFAQKAEAAGADWITVHGRTRRQRSHEPCDFDAIKLIKESVSIPVFANGDVFNLSDKEEILKKTGCDGVMAARGLLENPALFAGYEKTPVECVKKFVELSLGLGSHHFIFHHHLMYMLEKSMSRAEKKHFNTISSIAGCIDYLTDHYGLEFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWR0</accession>
    <name>A0AAD5TWR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000668">
        <property type="protein sequence ID" value="KAJ3213878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWR0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="243"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="300" mass="34651" checksum="156A56A653DB079B" modified="2024-05-29" version="1">MKIIGPSCTHSSQKQNKREQFNTAANNSVLGCKNCLKHNTQYSLGSKELKTDTDTVQITDSFKITKNSIQSRNINSLQKKEDFLNFIPIKHNDKDNNLNFSNTANKVNDNFSIVNHLDFQKFNTYSENMLFKENNNVISLDDLKIEENEVDQEEREGKIKLNKNSNVFSTYYDDFRKRSANKNSIKNENRRKRDAVTEELSSAYLNIKSDYDNDMTDSEDSDTVLEDNSKKKIKSDAAKLKVFRCSFPKCVKSFKKIESLKTHATIHNKENRYALFAIPPLEEIQIWPDITDVFMALVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWU6</accession>
    <name>A0AAD5TWU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001226">
        <property type="protein sequence ID" value="KAJ3205190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWU6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="350" mass="40730" checksum="C767F04669ECA577" modified="2024-05-29" version="1">MLEELQDIPNSIYSKISTNEIYPSPRSTKNKSPKRQFSKNGYFEATLKSLKKPIKLFESVQSINQSKKQTNEKQQQVEKKKMNKIDQVFDNKINNLDVVGFDKIVDNNKKFFFENPQFDLDRWNNGFQKNEDLIETEYLEDDFKIDVPQNEDQNEEASLMESSEKFMERDHQFENDNIVNIKETPEEFFFHKPDLTKTPKKGIQKNSSLVGDNSLSDQENLDNIMKNSPFKKKTKNPFFFNADVSKNNIKNFEGNNDGVEAILFFNENVLFDDEIEDGKNKGFFKKNEENLDGSRKENTTDNGQSVVGSDNYRFENADIKNSLFDGVGFKSKLVEIENEFTGSEKSWFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWV4</accession>
    <name>A0AAD5TWV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000652">
        <property type="protein sequence ID" value="KAJ3214071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWV4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="15258" checksum="8CAF5A9AAE797F98" modified="2024-05-29" version="1">MLLFLDFVQFKLDSKSKTPMLETAEKVLDNEIKVKSSEEVDLENNTAGERKQDDNPIKRYSILRVINTEVEEESAAFSVFLPTGTNSVEEIYEISFLRASGSPSEECNLFKQVNQSQSSHPKLLTVKNFTDFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWY3</accession>
    <name>A0AAD5TWY3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homocysteine S-methyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HMT-1_2</name>
        <name evidence="7" type="ORF">HK099_003457</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002260">
        <property type="protein sequence ID" value="KAJ3198805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWY3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008898">
        <property type="term" value="F:S-adenosylmethionine-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033528">
        <property type="term" value="P:S-methylmethionine cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="entry name" value="Homocysteine-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051486">
        <property type="entry name" value="Hcy_S-methyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46015:SF1">
        <property type="entry name" value="HOMOCYSTEINE S-METHYLTRANSFERASE-LIKE ISOFORM 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46015">
        <property type="entry name" value="ZGC:172121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="Homocysteine S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3198805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="16168" checksum="38E2B82806E913E9" modified="2024-05-29" version="1" fragment="single">GGEILFDKEKCKIVKDVHLQYLISGADIITTATYQISLPAAILLANEARNEFLEKNKTKRKPLIALSLGCYGAFLANGSEYTGNYGNVTEDEVYNFHLERLKTFLNFENFNDFIDILAFETIPNAFEVKVLKNLFQNFDLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX39</accession>
    <name>A0AAD5TX39_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol-3,4, 5-trisphosphate-dependent Rac exchanger 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PREX1_2</name>
        <name evidence="2" type="ORF">HK099_006879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000621">
        <property type="protein sequence ID" value="KAJ3214421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX39"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF159">
        <property type="entry name" value="LD03170P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="1">
        <location>
            <begin position="8"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="900" mass="103214" checksum="19D560D065869B1A" modified="2024-05-29" version="1">MTDSSHRRYLSLQKELIQTEEVYIQKLTILVSSFPLSLLSLTLTIKSLLSFQIKFYNSLLQEGDNLAYAFLNMCEGEFSIYNEYCSKHDNSLKLLRELEKKSDFMKFIKEFNTLSKEKLEIRDYLILPIQRICRYPLFLNELFKLTSPSSDQYEPLQAALNMMKKVISSIDWSKWYAETLEKTDKLFSRIMENNCDDLEAKEMFGTGLQGIQTNRLICGGEMLLGSTKKSSSYILQHAIKIDSICKVQTLYNQSQFPSAFRVICFDSFATLQVYDFSCSSDTQMLIWVQMLEKLTKEFSLEDIAGEMTAMFDKSLNNLFVNERVEFLSMEEKKPLIPTIPTKLDLEVQNMVEETWKSTRFRIELENEFDDTSGKIGAIADKSTVFPKRITSLKRNVNSTAVHLTRRRGTQISTEHTIENHSNIVMCQEPKSIVRSSSVSSRRSLSKLLEETETFNCSNNLSKKKETRNSFPTFATFLNFIPSEEPVKRSQSTTSLQLYKQASANLVNKKKPPVFKRPHSLYIPAFTNSTQQYNRSFLVDDLSEESGTPSSAATELETLIFNKDVSFNLQKVNRRLSVDTKLGDVLSAVNTTGVGSMSKLNVDEMVAWSSGRLSKINKYMATPLNRSDTTASEKLTDSSSITEVLLVNSTEESNAVEKINVFSENIRNTEIQVKSKDCLLKKKKRTVEFQLFSEDENSLEDEDDIPLKLFTKNLCAINKSNKAALVNNNLLQEKVEISSTIKTSATTEKKRKKFNFKSFIRDTGKQQPSPQKENLKVSYLHPKKTSNSRLQTLNGSLGLTEMDNACPELRYSISFDEATYLRSKPQNCNMNNSARNGELFSHKPTRRCSEEILTVKKFNFKSFKEKSYSCNEVDNQEYNLKKNYFFSSWFKNFGKRDKVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX42</accession>
    <name>A0AAD5TX42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NDT80 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002134">
        <property type="protein sequence ID" value="KAJ3199339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX42"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="3">
        <location>
            <begin position="131"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="131"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3199339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="283" mass="31783" checksum="86BFA7D8913E2E91" modified="2024-05-29" version="1" fragment="single">MNSFQPRSQNDKIFPNKPTNNLNLTISTSNLKNGHEIENIPFNFLNPEKELNLNSTSSLNSDTNFNLNSGVNLNSNINLSPNNNVNSDSSNSPLAKKITNLQEFSNPNLITNKVASSVSNFTESAALQYSNNPISLSTGTFDINSTIPSNLIYKSNDSESESPNSVNVSPNTSEIPFFKPTKQYLNIFSYDKRKIYTVSLIPKIDRGFFLFDDHWTCYRRNYFQVSAAFRANDAQGNDVKFPALLEFDNKLFTMIGFSINISAKNLLDEKPIGLVQHTPKRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXE5</accession>
    <name>A0AAD5TXE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002744</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001936">
        <property type="protein sequence ID" value="KAJ3200278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXE5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3200278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="120" mass="13711" checksum="DF060094296FDC07" modified="2024-05-29" version="1">MKSSSNLLVLGSGDSGKSTFIRQMRLTKSNGFTQEESAFFKLSIFQNICEILEALLNAIPKLNLEYEDTLKYTETLKEISQKNLNNKENEMIVKEFLNSKVVKECLNRKTEVPELQDTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXE7</accession>
    <name>A0AAD5TXE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3533 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000621">
        <property type="protein sequence ID" value="KAJ3214422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXE7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022703">
        <property type="entry name" value="DUF3533"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12051">
        <property type="entry name" value="DUF3533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3533" evidence="2">
        <location>
            <begin position="148"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="384" mass="43349" checksum="C1A31B7F3B5F3BBC" modified="2024-05-29" version="1">MTNKIETNYTIEFGSTNQETANAENFDTKQTDVDINNDFLQKNNISECTDLESNHKIANENRNLNTTFVYLLKKRLLAYCNIFIQALFSGFLTSFFVWAYIGMSWDIDTKALNVAVSMERMFKTIIKKCNKLMKNKKEFTNPVHVAIVNATFLQATPALFEVYSVATTSTHQSREHLIKDIESNKIWSAFWIPTAYGDNINEKTNVAKIEYIHSGAKQWNTDKAVTQGMKTFEAKWRIAVGNALMEKLNKENNSTTPLSNFFIDGPVGLEYTDLHPIDKEGQNFSSFIGPIVLWVAALFGVTISCKVKQHDSKFKEGVARVICVILITGVNAACVAIVPMILPGGQFIGDTRLMSWMWLFYIGLCFSSIISCLMCVFGKIFGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXQ1</accession>
    <name>A0AAD5TXQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-6-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PMI1_2</name>
        <name evidence="2" type="ORF">HK099_006557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000574">
        <property type="protein sequence ID" value="KAJ3215030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXQ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309:SF0">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20511">
        <property type="entry name" value="PMI_typeI_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphomannose isomerase type I catalytic" evidence="1">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="93" mass="10538" checksum="A39A377593E0103F" modified="2024-05-29" version="1" fragment="single">MSYEWGKVGLESKVANLIQHSNQVDIHKPYAELWMGTHPNAPSKLKNGELLSSILTKDILGEKVFEKFEKKLPFLLKILSIKKALSIQAHPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXS3</accession>
    <name>A0AAD5TXS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000859">
        <property type="protein sequence ID" value="KAJ3211028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXS3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="310" mass="35054" checksum="F5AD949EB4A10BD3" modified="2024-05-29" version="1">MQIKIPVSMADTLGSRRDSASVTLANLNTEVVTKINLFIVNEKVNTNSNIEDSVSDGVDIEADNDSTEVPINNLPENTEEDNSITNQGIIYESEEFKQVGIFKRLNLGINELYHFLIDVEKNTILQFTSLKRFKAFIYKRATLINEQRKKAEIYREVLATLSENVHLNTIGGINNSGLQLLLPSENGNFEIAVGVNNYDLVKPIAGLLVYDGFQCMLCSDISNDTHLKPFYARSVKMMKKHLILVHGTTKLPYSLCKVQKAFSNNKTPYKYINNRFFGVKVEIVQDCGDDEITEYSENELLEILERVIPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY74</accession>
    <name>A0AAD5TY74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MORN repeat-containing protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MORN5</name>
        <name evidence="7" type="ORF">HK099_006173</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000517">
        <property type="protein sequence ID" value="KAJ3215829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY74"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042814">
        <property type="entry name" value="Morn5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46437">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46437:SF1">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="106" mass="12202" checksum="4EF340BCA6B564B2" modified="2024-05-29" version="1">MAFYGSPFLAEQKNERIEGKGKYTFPSGNIYVGEFKDGKFHGKGIIHFKTGGQYEAEWINGIAQEGQYTFKDGLIYEAENWDYCTKEDRRFFAERVNGFSAGIKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYT2</accession>
    <name>A0AAD5TYT2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">VPS41</name>
        <name evidence="6" type="ORF">HK099_005778</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000466">
        <property type="protein sequence ID" value="KAJ3216670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYT2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057780">
        <property type="entry name" value="Beta-prop_Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23411">
        <property type="entry name" value="Beta-prop_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23556">
        <property type="entry name" value="TPR_Vps41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23413">
        <property type="entry name" value="zf_RING_Vps8_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="CHCR" evidence="3">
        <location>
            <begin position="615"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="838"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="994" mass="112938" checksum="7A5790122201923F" modified="2024-05-29" version="1">MKTLNEESQSEDPSAEKSDELLSEPEKESTSQEESSDEECDEEPKLKYQRLPNVSSAITNDTISTMGVSDRFLALGTHSGKLKILDFDGNDVKKFDAHSATINQISIDTNGEYVCSSSDDGKIAINSLYSSDSYIFNYKRPVKACALEPDYSKKSTKQYCSGGMAEYLTLSGKGWFGNTNVVIHSGEGPIYTIQWRGIFIAWANEAGVKIYDTVSQQKFAYLNRPPGSPRADLFKCNLCWKSDEELLIGWADSVKIGRVKERSKIDIASGMPKHSFEITFKTDYVVSGIAPLNDDLIVLLVFLANAASESQNVNIIGQPSLRKKSKPPEIHVVDYMGNLIANDVLSLTGYEKYNANDYKLEYLPAINSTENSFYLISPKDIIIAKPRDIDDHIQWLVERKEYKEAMRVAEEEEMKIAATGITSILSNKVKNIVEIGQKWLTSLIYEGRFEEAASNCPNILRKDCKLWEKWFFSFAEAKQLPSLHATIKSWPADIYNLRIVINAVEDALQRYPNNESLMETLFDLYARSYLLRKPNVLALIRQFNLYQFLCDSQTVNTNLHLIPKIPLLFDYIEWNAELSWKARIEEMDQKGKEKYKEKVSAYIWKIRKATEDEGVNILVEGVDRIPVSVVVEKLKKHQKYLHIYLDALFKKEIQDGLDYHNLQTKLYAEYDYPRLMDFLRTSSSYSIQEAFEICESRDLVPEMVFLLGKMGNNRKALMLIIDRLGDVNRAMEFCKDQNDEELWEDLLRYAMDKPRFIIGMLENLGAFVNPVRLVKRIPNGLEIPGLKEALIKVISDYSIQISLREGCEKILVNDTLQLLEQLYKSQKKALSLTGDEKCSICEGYVSFDGLQLDDVSILVFFCKHAFHSNCLKVNNLGSQNSIVSFSDLSNFSVAKKFENAIKVNYSSKPQFNLSDFKSLHSGKNEEVLKADISNSVKKEDVNYHSSKEGENTLDVTEKIKGKSLFCPICGDGKKKYDPSANSDTLLLKKKGLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZK6</accession>
    <name>A0AAD5TZK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000382">
        <property type="protein sequence ID" value="KAJ3218393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZK6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="234"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="498"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="593" mass="69216" checksum="93BC44E65F63EA44" modified="2024-05-29" version="1">MSDRSSAPVTKSNAFRPFDEPERPVSQPVMQPQRPMQQRPMYAAPQFRPSAQYNHPSQNYRPNSGFQGPSGQYRPGNPYGNQLPQQNYRPGFPNMQGPYQPPPGNRPPGNQINNTQFPQPPYHQRPISGELMRHNTNSSQYSQSSLTRPTGSPQPQSDLEERLRDLHNENKQLMAQLHKYREDDRRLVLLQQKQNKTLSQLDEELNVGILEISRLTSINAHYEEQLKNIAIDNDREYKSQIEALTLELESLKKENLILEEKLEELPETERILKLTQEELRKKENEQRETLTELELFSKEIVELKANLESKIEINERLTKEFAHDKERRIQLENQIANQLGTSADLVSDIEGRLESAEMKSSQFEKENTRLSGELAASKHALDVMTKKNLDLEAHCDEAEKVYDQMAQIINSEREKMSAMDFQLEQFQQNYQRMEEEKNLKINDLEYKLEEKTLETEGFFESLKNSEGGVDQFLYEQTLSLRQQITNWQQKELDFNTKINELRAEKDEMHKRLQEVLEGKLSEGNNQVEVEISLRNSNEELKAMIDELKLNLQNLEELKNFEFQDLKSQFDELVSKNFELNEIIATNNGNVRTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U042</accession>
    <name>A0AAD5U042_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000702">
        <property type="protein sequence ID" value="KAJ3213507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U042"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042104087" evidence="1">
        <location>
            <begin position="18"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="15719" checksum="BADB1AA8E21200E4" modified="2024-05-29" version="1">MQFKVLIALAVASLVACAPKPPVQSTCLVARDSTCLVARSTAPIKDCDQCHCLVESAGICLLARSEIPIKTDSTCLVARDSTCLTARSMIPSSEGMLVASGEIPEESTCLVARDSTCLVARSDIPIKEDSTCLVAIDSTCLVARGDDEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U043</accession>
    <name>A0AAD5U043_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD repeat-containing protein 5B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">WDR5B</name>
        <name evidence="6" type="ORF">HK099_006253</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000529">
        <property type="protein sequence ID" value="KAJ3215652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U043"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000228">
        <property type="entry name" value="COMPASS-like H3K4 histone methylase component WDR5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059122">
        <property type="entry name" value="Beta-prop_WDR5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25175">
        <property type="entry name" value="Beta-prop_WDR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002394">
        <property type="entry name" value="GN-bd_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR5-like beta-propeller" evidence="5">
        <location>
            <begin position="81"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="82"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="124"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="208"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="251"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3215652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="377" mass="41597" checksum="8FE66B04A6774C61" modified="2024-05-29" version="1">MESRKSPKIGAKSPSKSISKTISKTVATKRLPPLENDDENNDNINENISQQATKKPKQTNESNSSLQQADKKLPNYKIKYTLIGHKKSVSAVKFSPDGKWLASSSADKTVRIWNAIDGRHELTMTGHKLGISDVAWSSDSLFLCTASDDKTIRVWSVTSSESIRTLKGHTGYVFCVNYNPQSNLIVSGSFDESVRIWDVNKGKCVRVLPAHSDPVSAACFNRDGTLIVSCGIDGLIRIWDTATGQCLKTLIDDDNPPVSFVKFSPNGKYILASTYDSTLRLWSYSTGKCLKTYLGHENTKFCVISSFSVTGGKWIVSGSEDKKIYIWNLQTKEIVQVLEGHKDVVLSVACHPTINCIASASIDGDKTVKIWIDDTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0P6</accession>
    <name>A0AAD5U0P6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Phosphomannomutase</fullName>
            <ecNumber evidence="5 13">5.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SEC53</name>
        <name evidence="14" type="ORF">HK099_004097</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 13">
            <text>alpha-D-mannose 1-phosphate = D-mannose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11140"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="EC" id="5.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the eukaryotic PMM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="5 13"/>
    <dbReference type="EMBL" id="JADGJW010000280">
        <property type="protein sequence ID" value="KAJ3220696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0P6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02585">
        <property type="entry name" value="HAD_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1240.20:FF:000001">
        <property type="entry name" value="Phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005002">
        <property type="entry name" value="PMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043169">
        <property type="entry name" value="PMM_cap"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466:SF0">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03332">
        <property type="entry name" value="PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00445">
        <property type="entry name" value="alpha-phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01143">
        <property type="entry name" value="C2.B.3:_Phosphomannomutase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01140">
        <property type="entry name" value="C2.B:_Phosphomannomutase_and_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3220696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="241" mass="27521" checksum="B3B4418AED649534" modified="2024-05-29" version="1">MSNWSTKQHPNILVLFDVDGPLTPARKVVSKEMLDLLSKLRTKVVTGFVGGSDLSKQQEQLGDNVVELFDYSFPQNGLTPYKLGKPLSSQSFINFLGEKKYQKLANFILRYIADLDIPVKTGTFLEFRAGLINVSPVGRNCSHQQRDEYEKYDLEHQIRPKFIEAIKKEFPDYGLTYSIGGQISFDVFPIGWDKTYCLNHLKGEKFDKIHFFGDKTFKGGNDYEIFTHPDVTGHSVKEIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0S8</accession>
    <name>A0AAD5U0S8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Flap endonuclease 1</fullName>
            <shortName evidence="15">FEN-1</shortName>
            <ecNumber evidence="15">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Flap structure-specific endonuclease 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">FEN1</name>
        <name evidence="19" type="ORF">HK099_004429</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Nucleus</location>
            <location evidence="15">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Nucleus</location>
            <location evidence="15">Nucleoplasm</location>
        </subcellularLocation>
        <text evidence="15">Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14 15">Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="15"/>
    <dbReference type="EMBL" id="JADGJW010000310">
        <property type="protein sequence ID" value="KAJ3220227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0S8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09907">
        <property type="entry name" value="H3TH_FEN1-Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09867">
        <property type="entry name" value="PIN_FEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000009">
        <property type="entry name" value="Flap endonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000003">
        <property type="entry name" value="Flap endonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00614">
        <property type="entry name" value="Fen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023426">
        <property type="entry name" value="Flap_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 15" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 15" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 15" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 15" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 15" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="18">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="17">
        <location>
            <begin position="147"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="340"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="352"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3220227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="391" mass="44397" checksum="A4A1023924C7C515" modified="2024-05-29" version="1">MGIKDLTKLIRAHAPDAIKENLIKNYFGRKIAIDASMSIYQFLIAVRQTEGKQLTDDSGETTSHLMGTFYRTIRMVENGIKPVYVFDGKPPTLKSGELEKRKGRREENEASLKEAVEEGNLENQEKFEKRTVKATKEHNDECRRLLKLMGIPFIIAPCEAEAQCAALARAGKVYASGSEDMDTLCFSTPILLRKLTFSEAKKEPIMEIYLDKVLEGLGVTMDEFIDLCILLGCDYCDSIKGIGPHRAFNLIKEHKSIEKVLINLDKKKHPVSEDWPFAEARELFRKPEILEDDNIDIKWTDPDEEGVVDFLVKEKNFNEERVRKGVQKLKKNRKTVVQGRLDGFFTTAPKDSTSESEKPLKLGKRKTEDKKGGVKKKVDTKKSGSKGKPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0U4</accession>
    <name>A0AAD5U0U4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Geranylgeranyl transferase type-1 subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PGGT1B</name>
        <name evidence="9" type="ORF">HK099_004381</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000306">
        <property type="protein sequence ID" value="KAJ3220327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0U4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF4">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="8">
        <location>
            <begin position="9"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3220327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="337" mass="37925" checksum="951EDD98ACE61A10" modified="2024-05-29" version="1">MLAEVDQKLVLACLKMIPQQYISADTSRLTLTLFALGQLDLTKNLKEIEISRANWIDWIYAHQYLTENNQNGGFRGGLFSGHKFDKNGNYKKDEYDLPHIAMTYAALLSLLILGDDLGRVNKTGVINGLKLLQSENGSFKPCEDSREFDLRFVFCACAISYILNDFSGLNVNKVLEFIVKCQAYDYGFAQNLNLESHGGSTYCALASLKLLNKLDLIDKKATLLWLLKRQEDGFRGRINKPPDTCYTFWIGASISMLEGTKFVDTVPLKTFLECCKTKYGGFGKSENCHPDLLHSYMTIAGLSIFGIEEGLDDLNCELNLSKNSFETLKNSCNWNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0X1</accession>
    <name>A0AAD5U0X1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000777">
        <property type="protein sequence ID" value="KAJ3212478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0X1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042039282" evidence="2">
        <location>
            <begin position="17"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3212478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="15495" checksum="A19C51E423F4A6C6" modified="2024-05-29" version="1">MKLSFFIATLLAFTTALPTPQEQVVAVDSAAGQNVEQAAESVSVLTPETTNPDAQGQAEAAAKAEAEKVDVVGACSDDITIPCSNDNQVVSINSIGGQNVEQAAESESVLTANTVSPDKNQQAQAEAKAEQDKQEVQNCVADDSVPCASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Y2</accession>
    <name>A0AAD5U0Y2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000481">
        <property type="protein sequence ID" value="KAJ3216373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Y2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="176"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="442"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="506" mass="56528" checksum="C848911EA649D092" modified="2024-05-29" version="1">MKDEIMVDNPKDTGPSTFPYPSLNLLPNHLQLQQLQQSYNSFNGDFDKSSFVSAASILSNNPNNAIKTSVSSKDNFDMKLPPTYDVIQNENKLKGLINTAVKQTENGKKKAFISKFNILTGKDNGSISSSSTTNSNSSALSAYSFQSSLKFGDEVSDKGQDEEMMEASSTLGQDEINRLLKIERSRNARVKTKDSLTELKEYIPTLQGKLRVPTPQLIKETVKHIMALGRLLQSSQDYQTKQQQEIDQLKAQILEHQVLINQSQNLIQIYIQKQQQEFLMNNANLSEIEKSLPLFLLTQKLQQELCLNNNGTFNFNNSVSTNGNLCGNSNLGMNSIDLSNFQLPTVSSSIPVATSASASSTSSPVSNTSMFSPVLLQQQLLPSQFFQPSEVLQQPLQQLPLQQQFTLQQQLRIPQNQSLQVKCPPKETPKIKSVSQPSVNSNPLPQGWEELTDNFQRKFYVNHANKTTTWLDPRRAKNIDRPPSISNSISSISSKLSWPFGSKNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Z1</accession>
    <name>A0AAD5U0Z1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rab3 GTPase-activating protein non-catalytic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RAB3GAP2</name>
        <name evidence="7" type="ORF">HK099_004234</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rab3-GAP regulatory subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000295">
        <property type="protein sequence ID" value="KAJ3220515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Z1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026059">
        <property type="entry name" value="Rab3GAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029257">
        <property type="entry name" value="RAB3GAP2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032839">
        <property type="entry name" value="RAB3GAP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12472:SF0">
        <property type="entry name" value="RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12472">
        <property type="entry name" value="RAB3-GAP REGULATORY DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14656">
        <property type="entry name" value="RAB3GAP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14655">
        <property type="entry name" value="RAB3GAP2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab3-GAP regulatory subunit N-terminal" evidence="5">
        <location>
            <begin position="10"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Rab3GAP regulatory subunit C-terminal" evidence="6">
        <location>
            <begin position="796"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3220515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1109" mass="128514" checksum="FEA9B07931222B52" modified="2024-05-29" version="1">MISDFNSNVDSLLQKTQLLQFKKYLFNFQEEINDIVSLGYGSFNFLYRYDNPTNPKLFTSRFLSVGSFPMLSLNCTTENNSALSKVSNVISSAVLTFAKSLWNSPATTPNSSPKNLAEINSKDSTAKSTILAEESSKEQQQLMEQQAKVIPSVFYLDDPDRQVLTISLSPRSPLSLNSSFAALVDNLGRVSVLDLQSGEIVMILKGVRNAQVGWIQTYNKAYIQGNTLGFKKSFEGNTRFKLLLCVYLQRGAVEIYEVRSGKKISAFQTRTNLILCQNSSVTVGPQKFNSEIQMASLSNLSLEELQKNSTNFDDDVVQFSNGRRYRLANCFLVSKNGSIEMIDVNIELIRYLDNGYEQYVKLENFLANYDSFLGNDQQSEEGNNKRMEFLIRASTLYGDIHYVKFQERGWKILLQSLKIDEFDFILRTLEYNYKEINENERLKIYKKIYLQGECYRKLLCANVKNPAYPALDAICEAEVDCDALAEESLTELNIFLDNTKPDEERIKSHAEKEDSNYGSLSNYSLPFEEYYGFFEVNTDIDEENNDETDDLTYYTAELLTINRKFRENELYLLNISIFLFEKVIFEKIEFDHWCNKVYKCVRLKSIDWITLLLIFLSNYTPNSKFNFFDNSNFNLKLILKIFIKIIDGCYSKFNFKVEKENISSIQREKILNFESVLKLENFICDYLFKNLERVDICLLMCSAMKTLFKKYNFKTILYEKILRNLIDLKFLRKLTNDTFFFNLHINAKNFGQMESLSIHKILASYYVAECMHSDGTVEPELNELQSKINSESKMTVWICFSQFILPDLLMAYTSFEFGEKFVSNNYSTKYLKLSIQSCSKIVSPAMRNITISGLWSKYLSQKLKTILQVIEKGRKSPNEKMCLKLIGMNVDTCKIFLLLLMEVLSMLDLSEKKYLISVDLISYLNGIFDLHFEKFFYERINKSFNKCTLNNVTKECENRNSRLSTDNVDVNKEEENFGFENVKYFDSLLGGSFFDLLENKVGLLEPQRIKTFNWLIECCFFIFEKEIKSVRPLRMVDVNKIFYNDNYGLFTFNDTNIINPHFAPKEVNSTKKISVFSERDSFLAKLSASLGVNGVEMITKLSSKMAEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1K8</accession>
    <name>A0AAD5U1K8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000674">
        <property type="protein sequence ID" value="KAJ3213805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1K8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="170" mass="20051" checksum="3BE76E802B591E6D" modified="2024-05-29" version="1">MWHPNIVTRFQHIDHNAQEKEYYIPYNALLNTIFKLEDGYFVAPQLYRIDGGKPIMFLEMKKTRDIHNISKRVDADEQMRERYTLLSKDVDIPILYGISAFGTRIAVYQFHKSSREVLPRELIPTDPSIVTDIAPIDGWKDDIIDEEGYNNFMIMVNEVKRMVIDTYSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1L9</accession>
    <name>A0AAD5U1L9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="1">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glyoxalase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000226">
        <property type="protein sequence ID" value="KAJ3221505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1L9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935">
        <property type="entry name" value="BETA LACTAMASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935:SF94">
        <property type="entry name" value="TENZING NORGAY, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxyacylglutathione hydrolase C-terminal" evidence="7">
        <location>
            <begin position="251"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="389" mass="44933" checksum="AE89EB35850B147D" modified="2024-05-29" version="1">MKNLLTYIKTTAMGYIMNSTLIYYYFRLKSTPLLFKYEKPVNFQGRNPHCKIFKGNTFISEDFEIIPVPYFEDNYSYLIFDLKFLTCVVVDPGDPQLILNMLVQENWDHSAGNLSLLNGLKLFQKHFEGIKVYGGLKDFSGFFTKWYTGVKNFVNDKDEIYVGRLCFKVFETNWHTSGHSMYLFDPIKSLNLKENNDELALSYPCSLFCGDSFFSGGIGMFFEGSSVDLHNFFTTSFQKIPTTTLLWPGHEYAFTNFQFAKEVEPNNLAIQFRLKDVKHLKYINSSSVPTTLAQESQFNPFLRIHGQAAKIVAAKRGTLISDYGGGGPEEIYSSVKNLLSERVKKIEEELKDELKKKWKRVEIREDELLEILVLQCLRVLKSEFIPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U245</accession>
    <name>A0AAD5U245_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000601">
        <property type="protein sequence ID" value="KAJ3214663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U245"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3214663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="620" mass="70698" checksum="4302DE471BDD5B5B" modified="2024-05-29" version="1">MESRSFILTSKLNVFNSKSSGGSQEGTFENNEFSETKILLNYVPKLVALLISIGVSYSSDVKGERALHISIPIFLSAVGFSMLSFVEDATSRFTFLFIIEPSFYLSYPLILSYALDNVHGETVRALVSAGLVCFLPFNSALIHLFFPDVETYTYPQFLEESAFGSNFFPIDFHLYILPAVFMLFSGIFVMIFYWMNRREEETLWSKTPGLRRLMTDNEETQAWDINDSEFDIYSSSKKSKKGKEKEVIETVKTSKIKGEEAFEMTSIYDEKEDEEDLSSSAGSTKKIFAYTGLNDKKKEKSKKDAFFVDDDDDRTLNNITINVSLLSQGSYQIESVVNKKKTVVTRTQHEVERLYNVLQLELKNHIIPSFPTCSMDLKFLLEKLTNFFNNLLNINDCLTNVNFLSFLESEFLFNPVVGNSINPGLEKSIGNNKSFFNFFGGGSNTQDNDVYFENALKLTNQIDIGIIEIGKLCEKLARSEKSYSIHCSDLVTKFGVLAEETSPVESYQMLSLLSEYEQQCKVTQKKIQNLEKLKSSSSIKTDKVDVASNELFEVKKTETEVKDTLTSTSETIKREYDDFKFLQDYELGAELDKFVGKQLQVNKNLLKVWDNILKDLESLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U250</accession>
    <name>A0AAD5U250_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000206">
        <property type="protein sequence ID" value="KAJ3221829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U250"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="14604" checksum="18CE6C1647D62D2D" modified="2024-05-29" version="1">MLAINKRQLLGILDDGISCNIGRLKAASGTSAGLDSISELEDALPANAPAALKNQVKSCKENMQKASDAIGRIKDALLSGDAPNEADRDETEAGLKGATADIAKIVTNPTITGDADLQEVAEEAQSKIAKAGEGGTQVLEEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2B8</accession>
    <name>A0AAD5U2B8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">rRNA methyltransferase 2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FTSJ2</name>
        <name evidence="10" type="ORF">HK099_004920</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000363">
        <property type="protein sequence ID" value="KAJ3218830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2B8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF18">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="9">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3218830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="816" mass="90400" checksum="C8360614CF6AD480" modified="2024-05-29" version="1" fragment="single">DIYDEETWKKVEEVTNTKQVDVIITDMAHPFTQSKEANAARVFDLCFKAIDLVDLKLKTGGNFCCKFFQGVEQEQLHLKLKDRFEKVSYFKPLSSRKESAEASPTKILVNNENSFDQLGLYSYVGCYEIKEDEVREQFSRVNPFLGLYAVEDCAKLCLLSGYEFSALAAAGGTEAKRAQVDHTFQSCQCFSEVRNQQEVSRDYCNFSCLLTSKALAEANVEPIFVSSEATWNNIVQKSINGCGGYTVSNNKENTTDTSSTDDVALGKIFDDKNSTLNTPAITLFASFFTLSAKQSIFAVNNVLPTGIVQVQFQKPSSIVGGEDPSTTVMTTVPSSSSSSFSLRTISLPSVSSTNINTLSFPPNPTLVSSTESQPFIWDDPSENVFTTVGSNVFSLTTTTVAIEWPQPTSDDGPVTSQVPTSKSETNNDNFPFYISIVLGFLAFGLFVGWQRRQKKRVPKTPTKMQTLPELQMLPSASVLDSNTVSSPSSLTFNIPTPPNTVNSSSASVVKPIDREFLESKSLDYPQPPPNTPLNLIKNQLKLKSSFSSFPSITPPQPTLNSIKGSLISTRPPSTTEIPITEKNSVGENDYFSSELRLNSQESSIYQRSILEFENSLPYSYPKTPPNSFELSTATAANPIDIKELLKSLALLKSEFDELESITNSFSSLSRISGSNKMDNEEKRFSLDKNELSEKLYSFVNENPFDSEVLKSALQELKNQKSSSTIDILEEKEKITKVQYKNNNDAMVNAFDLASRLETLANESDFSVELDSKLSVHSQLKFSDSSEKNYVESSDSIADDDYLEYCFSDSDSIESPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2E6</accession>
    <name>A0AAD5U2E6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kynurenine formamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BNA7</name>
        <name evidence="3" type="ORF">HK099_002711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000192">
        <property type="protein sequence ID" value="KAJ3222096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2E6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="2">
        <location>
            <begin position="18"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="275" mass="31476" checksum="6EA7590D25AB6FDF" modified="2024-05-29" version="1">MQFYNIPYNNNENKKESLDLYIANKSDPNLIIFFHGGAWRSGDKSDFKFMGEIFLNFGYNICILTYNLSNKNGEGPYHPSHTLDCSKALHWLKFNSSLYLDNVENLYLIGHSAGAQISGMIALNPETFLFPLDNGLELFNAIKGVIGVEGIFSVPQLLKTHGHIPLYRDFIRQAFTEDMKLLENGSPQLLPLSKKKNFKLAPYLILHSKNDSLLNLDQPEAFMTTLNGLFDLNNDIKKDFKPEFDFDTLTEDHDEVLKSPQFFCAVINFLKKIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2G7</accession>
    <name>A0AAD5U2G7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bacterial surface antigen (D15) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006442</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAM50/omp85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000555">
        <property type="protein sequence ID" value="KAJ3215273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2G7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF18">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="6">
        <location>
            <begin position="168"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="494" mass="56670" checksum="09033040A1658EF5" modified="2024-05-29" version="1">MFNNNKKRKSEKEYEESLSFDMYEIKEYHFHVYFMQNDKQQVTHAKLLFEKLKAISTNEKQKKIKVSQLTIDTTESKLNITNKLLFDFQNSILKSKSFEQLILNYNNQIKLLTDLNIIKDAKIIIDGNTKDNLKTTVLFTPSKTILAKTGTNFGNSESEAYAQVSLNNISGTGDKLAANFMWNLYSDDLFKNDINFTGDLRRKFLGSYSRPLFYDPNLILNFKIKHQNNPYTLFSSFNERLNSLQVDLDFLHSPKSKHSIGYNLDWRENHTLNKEASLTVRNDAGSSVKSSLFHEFKFYSKKNFGFNFALPQETGYYFNLKNELAGFLPDYNIGDVNFFKSTVNSTFNLNFWKDFNLMTSFRAGLLYPLSSKINDKFFLGGPTSIRGFPHHTLGPKDGQDSVGGDLFWAVGTSLITPLPYIREAPLKGHFFFNSGKLSRFEKIEELKKPNLSVGLGLLCKFSFLRVEVNYCLPVVGESILHKGSIQFGVGTEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2H2</accession>
    <name>A0AAD5U2H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000201">
        <property type="protein sequence ID" value="KAJ3221924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2H2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="718" mass="82889" checksum="9E61F7DE5B513432" modified="2024-05-29" version="1">MATKFSLAPVVENNYSDSLESRPSSTEKKQTFSNRNSDVKKIPIDNNHRVSVAISEQINQPITQSSLTTNSLDVTLPPLLKGESAKSISNSSKNLLNVNSFSAYDKNNSRNSSQNYLNNKGNHQDLQNLETKIQHLEEPPNYAKLFGEESFSCSAKKKKFSISSLGYGTLKNSNASNPDQLQSVNSHQINIQQQQLQQSGNFNNNNNSIIAWWVGNKLSNATRKENEQLDTLLKKLNSNYLKEKIDKRFVTEEFDSDMGEAGSGLKGVSIFDKNFNEIQKLLEKIKNLDDKNHQNIANLQLQQQQNLNDKKKGNEKSEQQENQVAMAAATAFLDGNGGAMGNILGRSNSGTGLMRKPLRLIYIELNKRIENLKNSQSEWDAFQNKITAYKLEDNCEKTKYVTDIIQSNKVFDAYYPSKKLQLLSINKQKHDDRIKTVLENHRLLKSEKVKKVLMQIKKKDLVNNEKMKEQPKEKLGKTQLLQKKWFIAITLASKLNAIRDFLILRHQEREISLLETHSAIIIQKAWKKYKAAIQYEKVKTSLAIISRVFHKYIIYRREEEKHKASNLIRQFFRDVHDVSKLMKIVKKYRFSVVKAQQISRAFLNARNMRTLCICKHWESLVPQWWNLRKPNAISDDTSKKKKDKNQKPGKEKEKVKVIVEVPEHIKLQVIKEDYVERRKAYRKAMREYEMLKHNKPIKINSGKPDDIPELVKPVFKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2T2</accession>
    <name>A0AAD5U2T2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004639</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000333">
        <property type="protein sequence ID" value="KAJ3219595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2T2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3219595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="253" mass="27327" checksum="CAF8D58955DE2575" modified="2024-05-29" version="1">MKVENKVAIITGASSGFGSALAWRISGKGGKVVLADVVEAAGGKLEKEINKKYGDNTALFVKCDVASVSDTKNLIQKTLDKFQRFEIMINNAGIGEKVNFNEDINDNWFKVVEIDLIGVILGTRFAITHFINTKTKGVILNTASLAGLYPQPLQPVYAAAKGGVVHFTRSLANLNDMHGIRVNAICPSFSPTPLIKSGSAAEMLQGVPLVSVDQVVDAFMLAIEDDSVYGKSIRITPQLGIDFYEFRKSKSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2X1</accession>
    <name>A0AAD5U2X1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylthioribulose-1-phosphate dehydratase</fullName>
            <shortName evidence="7">MTRu-1-P dehydratase</shortName>
            <ecNumber evidence="7">4.2.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MDE1</name>
        <name evidence="10" type="ORF">HK099_005075</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15549"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="4.2.1.109"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aldolase class II family. MtnB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.109" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000380">
        <property type="protein sequence ID" value="KAJ3218437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2X1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046570">
        <property type="term" value="F:methylthioribulose 1-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000003">
        <property type="entry name" value="Methylthioribulose-1-phosphate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03116">
        <property type="entry name" value="Salvage_MtnB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017714">
        <property type="entry name" value="MethylthioRu-1-P_deHdtase_MtnB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027514">
        <property type="entry name" value="Salvage_MtnB_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03328">
        <property type="entry name" value="salvage_mtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640:SF7">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="9">
        <location>
            <begin position="39"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3218437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="253" mass="29098" checksum="FCF6ABE482C3952B" modified="2024-05-29" version="1">MQQTLKKRKHEENDVQNNATEGNDSNLSVLSSDPEHASNLIPELCKLFYNNGWVTGTGGGMTIRQHDHYYIAPSGVQKERMQPSDLFILNKNQEIISLPHNKSLKMSQCTPLFFNAYNLRNCGACIHTHSQNAVLATLLFSGSHFTITHQEMIKGIRRGDSKDYYKYYDTLTVPIIENTAEERDLKERMEKAILDNPDTNAVLVRRHGVYVWGETWEKAKCMTECYDYLFEIAVKMKKLNLDPTEVPKDSEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U313</accession>
    <name>A0AAD5U313_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">STUB1</name>
        <name evidence="9" type="ORF">HK099_002320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000176">
        <property type="protein sequence ID" value="KAJ3222417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U313"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045862">
        <property type="term" value="P:positive regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041312">
        <property type="entry name" value="CHIP_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18391">
        <property type="entry name" value="CHIP_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="CHIP N-terminal tetratricopeptide repeat" evidence="8">
        <location>
            <begin position="126"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="7">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="249" mass="28970" checksum="B3C8B52CE903649E" modified="2024-05-29" version="1">MNFQTSSEEFRKKGNDFFHQGLYEEAIKQYTTAIIKNPNNPLCYTNRALSYLKLNKFENVIQDCEKGLDLDPNSVKAHYLLGQALTHTSRLNESISHLKKAYALGVSQNVNYTADILAASRKVKTLKWEQMDLKRRETESDLYRYLTGLIERDRRRMLQEINEADSEYVDITNYEHDQRRSQVELLFSQADENGKKREIPDYVCGKISFELMSDPVIKPSFSRKPLLEKDLIPNLAMKEVVDTFIEKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U382</accession>
    <name>A0AAD5U382_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL11m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001741</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000152">
        <property type="protein sequence ID" value="KAJ3222935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U382"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000003">
        <property type="entry name" value="Mitochondrial ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="7">
        <location>
            <begin position="15"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="6">
        <location>
            <begin position="65"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3222935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="137" mass="14932" checksum="1AB34E1B14F4883F" modified="2024-05-29" version="1">MQKSNKIQFVRLLVPAVGPALGSKGVKAIDFCKLFNEKTKHFTKEIPIPTQIFVKPDRTFTFTTKTPATSWLLKKAAGIEKGSSRAGEVIAGEVSLKHIYEIGLIKQNDPGFAGTSLRDVCARVFGQCKSLGIKVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3P1</accession>
    <name>A0AAD5U3P1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 58 central coiled coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003289</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000218">
        <property type="protein sequence ID" value="KAJ3221633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3P1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049270">
        <property type="entry name" value="CFAP58_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083:SF0">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21771">
        <property type="entry name" value="CFAP58_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cilia- and flagella-associated protein 58 central coiled coil" evidence="4">
        <location>
            <begin position="537"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="376"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1041"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="316"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="645"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="813"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="966"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1046"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1067"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1088" mass="127236" checksum="B7F3391F3A078148" modified="2024-05-29" version="1">MSDINSNDMEEEDINKMVNEAMEPTSRRSTKLRLQQSSKENLADNTRQNAEEEITEKKDSLNEQIQHENSQLIDNKDGEEDIESQEVGMTGNVEESEEEEEDELDESERNIEEQKSTKINEPEEASVIENGKETEDTSNDKEKISEVEEELEEDEQDQIMLEDLKNTLQFFNQQSELPQATTDINFIRLNEEYDKIHKLFMQSRTNEKKLVKRCKELTTELNSNAAKVQAALKLSQNDRSTITGLKKEIRKAWKMVEAGSEKEARSKEAISSMKAEIESLHRGDDMASRGTVASPVSTGFSRQRNLEYQIGQEESIKELIQIKESLQSQLETALSESKQSKHEITELEGKLYTLTTERGALDYEVLTLKDLLATKKSESDRDGRAREKLEIQNRQNNEELKKKDQEFSQKILECKQLKEQNLKNDLALKEEKTRYEKFEKENDILSLKLTKMLQEYDEQVLTISSLVNENQNQNRNLKNMEEEVSKYKDELRNCTRVRDSLAKRIKVMEEAKEEAEFEKDALKGINHGILHDLDLGKKELSAFHKNIEALKRERDIAQKNFVRATGATQKQLTVVKLAEQTKRNLEQEIMGYKDEASKMRKLIYVLEKERDRHINDSCKAEQNLNASIEEVKMKEMHIFDSKKKITEMEKKLKEQQSMYENVRAERNLYSKNYIESQDEITEMKRKLKIMGHQIEQLKEEIANKESALGKEKFEHQQIEKEKESLSIQIGKLSIQHEDAQKMIRNQQAEENKLRHIITETDAERLRQNKEYEAVVQERDILGTQLIRRNDELSLLYEKIKIQTSTLNKGEIQYRERLEDIRVLRLEIKKLRREKAILQTETQNVEGLRNEIFKLQREVLRERTRVKVLEEELESPMNIHRWRKLSGSDPSTFELITKIQTLQKRLISKTEEVVEKELIICQKEKLYKEVKEVLQRQPGPEIAEELRIVKEAVKVKMRECKSLASELNMYHSQVNEYKYEIEKLTKELQTLKKKFYESKKKEKSNQDLQQRQEAQQKISLNRQEVNLQNCLQKNIPSGPKFAGGGFNLSTGPHQTVNFHAPPIANAPNKEEKVEDITSKPLEHDLATLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3X4</accession>
    <name>A0AAD5U3X4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">U4/U6 small nuclear ribonucleoprotein Prp4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PRPF4</name>
        <name evidence="5" type="ORF">HK099_003876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000260">
        <property type="protein sequence ID" value="KAJ3220966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3X4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001211">
        <property type="entry name" value="CBN-PRP-4 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="4">
        <location>
            <begin position="93"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="316"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="358"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="400"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="565" mass="64763" checksum="34B259C7B75050A1" modified="2024-05-29" version="1">MSDSEDENFLTSLNFNKPRIHFGSLEEEDKQKKLINEKSFLVKKIIKKGLILEDLSSNSNHLTTDSIPVDQAQLDLLESFEQKKKKSKFNLPTDDKKVRSKLQSLGEPQFLFGEDNGERRDRLRSVFEDFQNKWDFNDFHTIVNEFEEVDKQEVEDFEEEQEFLYPGDPELLECRRFLTAYSLPRAKERLELQSAELELMIPERKKIRHELYTHLKSLATFSSQFGDDRPLSYCTFAPNSKILATGSWSGPVKLWSVPESELLFTLKGHKDRVSGIDFHPLSTISQKRSELNLVSSGTDGKIHGWAFNNEFPICEFEGHEQRVSRLCFHPSGKYLASSSFDLTWRLWDVETQHELLLQEGHSREVFGIGFQCDGSLIATGGKDSIGRVWDLRTGRSIMVLQGHVKSILSLDWSPNGYQLATGSEDHTIRIWDLRGKGSGCISTIPAHTNLVSQVKYFKAGKGFLKKKERIEEAFNFNDDVSYDAMETEAEKEENVLKKQLLNGSYLVSSSYDNTCKVWTEGDFKSIKVLSGMDSKLMCCDVSSDCNYICTAGYDRNFKLYCPEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Q8</accession>
    <name>A0AAD5U4Q8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tetratricopeptide repeat protein 21B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TTC21B</name>
        <name evidence="10" type="ORF">HK099_000116</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTC21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000101">
        <property type="protein sequence ID" value="KAJ3224194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4Q8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000197">
        <property type="entry name" value="Tetratricopeptide repeat domain 21B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000219">
        <property type="entry name" value="Tetratricopeptide repeat domain 21B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056832">
        <property type="entry name" value="ARM_TT21_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056836">
        <property type="entry name" value="ARM_TT21_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056835">
        <property type="entry name" value="ARM_TT21_5th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056834">
        <property type="entry name" value="ARM_TT21_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056833">
        <property type="entry name" value="ARM_TT21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040364">
        <property type="entry name" value="TTC21A/TTC21B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14699">
        <property type="entry name" value="STI2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14699:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 21 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25058">
        <property type="entry name" value="ARM_TT21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25060">
        <property type="entry name" value="ARM_TT21_2nd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25068">
        <property type="entry name" value="ARM_TT21_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25064">
        <property type="entry name" value="ARM_TT21_5th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25063">
        <property type="entry name" value="ARM_TT21_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25062">
        <property type="entry name" value="ARM_TT21_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B N-terminal ARM repeat" evidence="6">
        <location>
            <begin position="13"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B second ARM" evidence="5">
        <location>
            <begin position="285"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B second ARM" evidence="5">
        <location>
            <begin position="376"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="662"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B fourth ARM" evidence="9">
        <location>
            <begin position="698"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B fifth ARM repeats" evidence="8">
        <location>
            <begin position="905"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="905"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B C-terminal ARM" evidence="7">
        <location>
            <begin position="1052"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="1178"/>
            <end position="1211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1266" mass="144579" checksum="01D727D5A168A967" modified="2024-05-29" version="1">MSLISAEEDLSTINYYLDLKYYNHCVLYCDGALNVKVGDPVLQFWKIFGVIMLQKGRQTEALRELQTLQEKRDLVLACPTAMIFIHERLQPVDYDAIEELQAKLVINSTSKNLSEKALITVALLHWRINQIDEAKTYFKQILSDVNANSSTARCFLGAVEAKNNKEYSFKSVLEANPRDLEGLMAKLEENKKKKKNESLCIDITSQIIVNNPNYVPAYIERMKLYLQSGNWELTLDAAQRLNGVSPNSIDALAVMTLHELCKEGDSKLATTYLSNLYDVIFITIMRVLEQCSRFLETALKLNPNKSECRSELAYVRLLQGNINVAKQLYEQSANEDADDIRSQEGLMHCQLLLGEYEHAEEHLDLFHHMSTNNSAKARIRFDYFIAVNPEYIAELLNDLSEFLPSTPRKDGEDIHQIIVLMLELVQLYCKIQPGSCNALYYLAKLKYLSNDQQSSQLHCSDCLKLDPTFLKAHILMAQIHLTNNHSKLATQSLEMGMSYNFEVRNIPMFHIIKAKALKMEGLYEEALNSLNFAISLPGIKESSESRSGNNTSLSERVSLYLECVEVHSKLNQTHEAAKIMEDTIRAFSTTEEEGRIIIANADLSIARGEIDLALQILSTITSSNNYFIEAKSRMADVYKIYKNDQRAYARCYSEMVDKNPSVKSWLLLGDAYMNIQEPQKAIAVYERALEVNPTAIVLAMKIGKALIKTHDYKKATQYYEHALTTPNSSLSLHCDLADLYRKLKQYDKAERTISKALDHPKSICIGKLIFKIFLGEDLTTDVKLYMLLAKVNEATNNFDKSINALIKARDMQIHILSRDSGQIENRENKVLASDICFQLAELLKKYLKDNEKGISYFNEALQFDTTSKKVVKALVALANLHMELNDLTSAQNVCATMLRMEVGVEEATIIMAEIMFKNNNYTAAIFHFQQLLEKSPNNYAALNKLIEMLKQSGNLDEAQKFFDMCEKGSEKCLLHPGYHFCKGLYYWYINNSNAALSEFNLSRKDGEWNIKATHNMIEIFLNPDNDTVGGDALESEEKPDEKTDSELLSLLTVEKLLKELPQKPPCLKTKTLEYYAIMGTKQKADIERALGKFMDFLNTERDYVPALLGTAVCHMLLKQPPRARNQLKRISKMDWTPEFAPEFEKSWLLLSDIYINGGKYDLATSLLKDVLKYNKSCAKAWEYLGYIMEKESSYKDAAIHYENAWKLQKQNNPVMGFKLAFNYLKAQRFVDAIDISQKVLSEYPEYPKIKKDILDKARSCLRMPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4W8</accession>
    <name>A0AAD5U4W8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U2 small nuclear ribonucleoprotein A'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LRRC49</name>
        <name evidence="8" type="ORF">HK099_008466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the U2 small nuclear ribonucleoprotein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4W8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044640">
        <property type="entry name" value="RU2A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552:SF6">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3224446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="347" mass="40236" checksum="E67F329BB1F020B0" modified="2024-05-29" version="1">MDGNTVANEELYRPIMITFVRPLKILDRKRILEEERRNFIKVIKREEEKRKEQEKQIIQSEKKCKAVAKIKNNWNLHKTTTIFSGTEKDNIEINCIDVEKDGFKKSGNWTKKTGFYTENTGDTAVENKDTYVDVNGGVLSIFGPGLGVLEKVMNNIEIIEFNYIEFEEIEQHLAKISKNYPALQAMRFTSNNLNHLYQLESLKVLKLNELSFSDEGNSIVSLGIFRKYLIYIFKNLPLEILNGIQIETCERIEAEKFFAGIKKIQNQQYQLFSTLNSFVSQTLDTMGNPSSIQDDASNIKKNLKPAHSLKSESKAYVKALIKERIEFNTKIKIFDEFWTNLVKEMCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4X3</accession>
    <name>A0AAD5U4X3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein casc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CASC1</name>
        <name evidence="4" type="ORF">HK099_008453</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNAI7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4X3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031826">
        <property type="entry name" value="IC97/Casc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023247">
        <property type="entry name" value="IC97/Dnai7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20929:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20929">
        <property type="entry name" value="LUNG ADENOMA SUSCEPTIBILITY 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15927">
        <property type="entry name" value="Casc1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02043">
        <property type="entry name" value="CANCERSCCP1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IC97/Casc1 N-terminal" evidence="3">
        <location>
            <begin position="14"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="636" mass="73695" checksum="57DDE1C47108C6A0" modified="2024-05-29" version="1">MNTFEEKKEAEENRLRLEEEQRLAEIRAKKEKELRDIREKEALEAIFKQEQERFQEEEIDIIRLENEKLAALAILLEERQLEADWIQHLDCSVLPDPKIEKDMNTFLSLLAQDNLIKENEPSLKNLFHLLPNVKILSLELEKQMCIAEDNQKTKEYARLHSHLVKLNEIINEKWDVLTADILQHIDYFTREPNENFQLTESGSDFNVGIWGNVTKNPRFKVIEFTDQNMSASLPKPLALSSVGIRMLYQLDSTVNTIYQENLIEGKLHMSPVCGILLLDIVEFPELPKIVDNWNIRQILSPNGKLKKLAYPFKKVVAEEEATDEKEEEAIDSISWPTLVSYQIQENCFIDKNSAKVMYFKEETKSWEDDNISDVEIDVEKGLVKFRTTHFKPTAVVQHTYSEYPYRSWQMYPIGKDKAIISIQGKNNLLELEVYKGECKLLSPSNNYIKNNLQDKYMSPRLLLKKISMLGLNFTAPESLIGLELEEDFILKNPVGDEMCSLGISLCAQSFCFRQSPSNRKISSSKCTFQFKEFKEGDIASSTEENDLIWNSVLFDVKYKLNDELFKVGFVVPGTTVTNETKFDFETQQSSIIHSSVYHMIKPYAIDPVNISRLETSSALFTRTIYQILKATKLISW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U514</accession>
    <name>A0AAD5U514_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000086">
        <property type="protein sequence ID" value="KAJ3224640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33667:SF7">
        <property type="entry name" value="RIKEN CDNA 1810020O05 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33667">
        <property type="entry name" value="SI:DKEY-57N24.6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="458"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="709"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="715"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1524" mass="175301" checksum="4EF8EC4018C03A6E" modified="2024-05-29" version="1">MHLDEEKDEAENLREACALGNYRAAKYYLEKHPALVNTQNKMNKWTALHWASSRGHLNICALLVDNGALKTLKNIKDQTPLDIAKSDEVKTFLSGIQVISSVNNKEENLEPFIPNYLKNPDLAKTWTIPVIDNPLLQLKNLDVTKDTITFNDSAKDKVLTKKEINSDTSESAMKILFAYHRVNAKFFTLGEFHFSSEEVRCMSLKDITRKLLSESDSSFSEDCNFFKVDRQYLIENYSLQGNTTISSTLNYTYLNKKQFHLKAFDFFRNNDYDNNNPINIKRTRKQKEKEFKQFFISYKIGNNFNGATEILQFDSTNLCVVNDFVVDAEFILGLYEKAIEVVIWEFKLEEDEPLVTKSQFKSFLMRNKELTNGLNENAEINIKKSELLSGYKKTVAKVERVAEMLSGFKETPKVKNDAVETECCVANNIEFEKFKGNKKKSKEKGMENFDKWLAFKGRSTKDDQDNQESNFPEKGEVKRTSTKPQVPVHNTEDVFQLSLELDGPNSHFSTCHQTKLENILKLKGKEKEKKIEPLSIPETRMPIKSTNLNSHGNALRVLAQITAQTLAANLLKNYGNATETLGQIKGKKTGPSPHHFDLPEKHVMGSKYNLYRSKSALSLVHSTPMTYVRQEPSPHHCEHPFTMLQRGSKANSVAGKSYISKNSKKSVVVKKIQKKEPNTRKKVFGKYLVKETEEKELNEEDKDIYIATKKKHMKGSGPSKSSTNNSKTLNKNKNKKKYSVKEISGVDDEENSTYVNDKKIVENLEKQWKEDKLNLLDSLENFKNAELIKPKTAKSEILPRSTEPVDDILKKKKKALRKNEYDNVLKRIDFNDINKKHHPLIKKKRLLNAVEVGRVIIDVTDFFLGEIDVQSDSGGVEGIESLKVNVGLDTPLFSDDQIELLNPMCIYVNSIDGMPNTPISYEELDKKCAPPYSSFKFFDEFFEYISKPEVPSRKPVINFYSKHVVLPGLMEEETLYNLFLNRKLEFKIHDRDIKIDDELINNSIGDVNIDKKNSFGVASFSLAEMILGATDLNLSIPILPPRNNDGPYHLPPGNWLEAHSSLNIRVKIKKPLFQNLKLSAKKPLENPEEFNDLIQNNIIPVTKSLENLKNAKNNSLVLQQHPLSRMFLFLSVKDNEMFNLIQNFVSENNCKALFQNESEFNLLSYYRLSPEQRMSNSLDILTGYDINDEDYRIMLIEGIREKGVEVLSKFITGLIASRPDNPLIDKPMLFFDPLNLEKKRNWIGLLPNLIHIKLKSNLHSLMSKSSTYLKKNLSKDCFDCLNILHQLVLAATKKNHLLTNYEGKLLANGQHCPTNSMINALLFQFGELVDSSHFQEIVSSEKSPNDIGNFSEINISGTENTRQVKKVEDLSKFNPERKETKKILAVLNKNKLKIFKKVDDKNLKFVQKIKYTHGLVQPNFIEIYNSKFNKFEKKENFYKRSKSYNKIHNYSIQELSSTCEQMHQLRHKISKDPRHFYAYGDRFFSQTVAPVDVIEEEKRQEMMSRSKWQTVHGFKRNTNLNSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U571</accession>
    <name>A0AAD5U571_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferroxidase</fullName>
            <ecNumber evidence="3">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_002755</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 15">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the frataxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000194">
        <property type="protein sequence ID" value="KAJ3222054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U571"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034986">
        <property type="term" value="F:iron chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017789">
        <property type="entry name" value="Frataxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03422">
        <property type="entry name" value="mito_frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00904">
        <property type="entry name" value="FRATAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3222054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="116" mass="13295" checksum="B5F5C035244CA763" modified="2024-05-29" version="1">MSEDDFFHQNADKTLESIQDNLDALDENYDIEGFDLLFSSGVLTVKFGMKGTYVLNKQPPNKQIWLSSPVSGPRRFNFNTKNNNWISSREEDNQLVLETHLSNEISKLLGVEDLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U586</accession>
    <name>A0AAD5U586_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000079">
        <property type="protein sequence ID" value="KAJ3224843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U586"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026680">
        <property type="entry name" value="CCDC137"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21838">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21838:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="275" mass="32707" checksum="BCFAFDE58B9F86E8" modified="2024-05-29" version="1">MGKNKKKENNDIPRKFLDILKFKQEYVHKSKNSKDKISNKPKLLPGENFKQFAKRIDDETRTLINKASQQNNKSRQKKIEYLKLKKVSKVKIKDVNKSEKNMFYEKVGKKGRGNEEGLVEKIPFGFQAQEPPKFSTLPKKRKEYVPKKHQLDLKEMEGDKNSQQKGDNKRDYELNPLLPPPPGRKQKLKNLNPNERLKILSERKKVIDIYRNLKIKKKKEILERNYAENAIGSNNNYLTDYENKQYIKKNEEVSFYQEEFEGLDGEDMFRKFEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5I5</accession>
    <name>A0AAD5U5I5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fructose-1,6-bisphosphatase</fullName>
            <ecNumber evidence="5">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">FBP1</name>
        <name evidence="16" type="ORF">HK099_000978</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5I5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000001">
        <property type="entry name" value="Fructose-1,6-bisphosphatase class 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF1">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="14">
        <location>
            <begin position="16"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="15">
        <location>
            <begin position="192"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3223557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="325" mass="35944" checksum="B7F625243DEA1A03" modified="2024-05-29" version="1">MSQRKEHGETKTDIVTITNHILMQQQQHAGATGDLSIVINAVTASCKWISNCVRKAELMNVIGLTGGKNVQQESVQKLDILSNEIMINMLKSSGRTAVLVSEEDDQAIFVEDNQRGHYCLAFDPLDGSSNIDCGVSIGTIFGIYHVLDTERKGELKDILRSGKDMVAAGYCITLDPNIGEFLLTHPKMRIGKKKIYSVNEGNAHTFDPAVKSYVHSLKFPPPNFEGKFTPYSARYVGSMVSDVHRTLLYGGVFMYPGGKLRMLYECFPMALIIEAAGGKASNGRQRMLDLLPPSIHARSGIFLGNKEEVEKIEELYRKLDAGELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5I8</accession>
    <name>A0AAD5U5I8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">mitochondrial processing peptidase</fullName>
            <ecNumber evidence="5">3.4.24.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Beta-MPP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">UQCRC1_1</name>
        <name evidence="18" type="ORF">HK099_002523</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.</text>
            <dbReference type="EC" id="3.4.24.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000184">
        <property type="protein sequence ID" value="KAJ3222248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5I8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000002">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000001">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="16">
        <location>
            <begin position="48"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="17">
        <location>
            <begin position="200"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3222248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="472" mass="52748" checksum="59A13B255A047B2E" modified="2024-05-29" version="1">MNRLLSRRFISNITTPTPASTSISYTYQKSLGNLPETRISRLSNGFTVATETNPNLQTATVGVWIDAGSRFENKKNNGTAHFLEHMFFKGTKTRTQVDLETQIENMGGHLNAYTSREQTVYYAKSLSKDVPKAVDILSDILLSSNFSKDAIERERDVIIRESQEVDKNKEEVVFDHLHAIAFQGTGLGMTILGPIENIKSIQQEDLLEYVKENYTSDRMVLAAAGGVDHDQLVKLAEKHFGGLRPGNVRAKLAKAHFTGSDLRARYDNHPTAHIALAVEGVSWTNQDYWPLLVAQSVIGSWDRSLGAASHVSSQLAQKLTEQPFKSLGYLANSFMSFNTSYTDTGLFGVYAVSDNFTHLDDLVHHIQREWHRLALNVTEIEVFRAKNQLKTSLLLSLDGSTPICEDIGRQVLTYGKRLTPWEIDGLIERVTAKDVMKVAAEYIYDREVAVVGYGPVDGLQDYNRIRAAMSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Q9</accession>
    <name>A0AAD5U5Q9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">DNA topoisomerase 2</fullName>
            <ecNumber evidence="5 16">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">TOP2_1</name>
        <name evidence="20" type="ORF">HK099_002321</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 16">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="16">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5 16"/>
    <dbReference type="EMBL" id="JADGJW010000176">
        <property type="protein sequence ID" value="KAJ3222418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16930">
        <property type="entry name" value="HATPase_TopII-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03481">
        <property type="entry name" value="TopoIIA_Trans_ScTopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03365">
        <property type="entry name" value="TOPRIM_TopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000003">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.30:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000008">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000004">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.670:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.199.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034157">
        <property type="entry name" value="TOPRIM_TopoII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15 16" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13 15 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15 16" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="18">
        <location>
            <begin position="395"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="19">
        <location>
            <begin position="641"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1125"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1358"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1371"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1404"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="15">
        <location>
            <position position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00053943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3222418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1428" mass="162989" checksum="09FE2BD0584184F8" modified="2024-05-29" version="1">MHARVFENEKLVYRNVNYVPGLYKIFDEILVNAADNKTRDSKMDTLKINIDKENNKISVYNNGRGIPIEVHKEEGIYVPELIFGHLLTSSNYDDNQKKITGGRNGYGAKLCTEFIIETADSNSEKKFKQIFSDNMSVKSKAVITENKKKENYTKITFSPDLTKFGMDSLNDDLEALFKKRAYDLAGCLNGVNVYLNDQKLKIKDFKQYVELYISSSKGSTDGATSRPGVFYQRFNDRWEIAVTISDGQFQQVSFVNSICTSKGGTHVNYVSDQIVATLLETIKKKDKKSVTLKPFQCKSHLSIFINCLIENPAFDSQTKENMTLKSSAFGSKCTIDDDFMKKVLKSGILETIMSFAQFKQQQALKKTDGKKNSRITGIAKLDDANNAGSRNGSQCTLILTEGDSAKTLAVSGLGVIGRDNYGVFPLRGKLLNVREANHSQIMNNAEISAIKQIMGLKTGQVYTDTSTLRYGHIMIMTDQDHDGSHIKGLIINLLDHFWPSLLKVPNFLLEFITPIVKVTKKNQERTFFTIPEYEEWKSNNMDAKGWHVKYYKGLGTSSTQDAKKYFSNLHTHMKEFRTCSENDRNLINMAFNKKKADERKEWLRNIEPGTFMDHSQQQIPLNDFINKELILFSMADNIRSIPSMVDGLKPGQRKILFCCFKRNLVNEIKVAQFAGYVSEHSSYHHGEQSLCTTIVGLAQNFVGSNNLPLLEPLGQFGTRLQGGKDSASPRYIFTKLNSLARAVYHPADDAILKYLNDDGQNIEPEWYIPILPMILMNGCDGIGTGWSTSMPNYNPRDIVENIFLLMEGKEPKPMCPYYRGFKGTIEKQDKGNYKATGIIRKLSDTTVEITELPLKTWTQSYKEQLEEWLVGTPKVPAWISDYKEYHTDSMVHFVVTLTEENLAKAEAEGLEKKFKLTTSLAISNMVCFDAEGRIQKYDTTESILKEFFSLRLQFYQRRKAYMLEQLAQEWTKLDNKVRFVLEIIEGTLIISNRKKADIISELKKKKYTAILKVKDLQKDAPEDLESQGDNGYDYLLSMPIWSLTLEKVQKLIDEKNQKDTEVLLLTKQTPQDLWRTDLDHFLQKWEVFEEEMYELETKEVTGVSKLKAGISSKKIKKKLYDTEEDDSDEFTAEKKPKSVAKKPAAKNHERKVDEITASVANIKLEKQTVKKRTVKKNNIDEKDTTTENKDTTKVENSVPEIEVKKPNGRNKRTANIKILSEDSNLSDTTDDEFNMKSEKIDVKFIKEVKRPTKKILSKPLLENKSKNLDKKSKIEFAEEEVVDSESKENGLDFKKKNPANTLKTVYKSKKKILDSEDDDVFENFLEVKEEKNEKKGHSNKQNTTVNKKIVTKIILSDDDEPPMKITKKPSKIITSPPSTSSESVKETNVVKRGRNKKPVNFTFDDSEEEDVISSEDDFKVDDFDMTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U691</accession>
    <name>A0AAD5U691_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal protein bL31m N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000091">
        <property type="protein sequence ID" value="KAJ3224503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U691"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034600">
        <property type="entry name" value="Ribosomal_bL31m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048874">
        <property type="entry name" value="Ribosomal_bL31m_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28174">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L36, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28174:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL31M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21492">
        <property type="entry name" value="bL31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein bL31m N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="121" mass="13938" checksum="EE19202A74296B60" modified="2024-05-29" version="1">MFQFYQTIVHTDGSTFTLKTTTPRPLLKLTKDTRTHPLWNPERNLELDKQSKELKRFNERFGTLDENFGITTEATTNSERATDSTADENLFGFALGKTKEKKKVEVKVEEVKVGKKGKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6S7</accession>
    <name>A0AAD5U6S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000069">
        <property type="protein sequence ID" value="KAJ3225170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6S7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="250" mass="28083" checksum="187E3463B6FCA04E" modified="2024-05-29" version="1">MSIIKKENGKFICVDTVNLNPELKAEIDSLTSNGSLIEAVIATHPYHTLAFPDFYLNYPNAKYFGTPRHLKIFDNTVIPWDSELLCENSLRQFEPDLYLRIPDGAEFVNPLPPTTNHFSNIFVFHAKSKTLHNNDTIMVFENPGFLLSFFAKHGDVKFHRSITGPGLYPTKEAPFQFKNWLEKLILDWDFDNICSAHNGNLIGGAKVALKNTLEKFTPTLQKISDTNAAGGVVTNEGAWTDKPNHPTECG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Y1</accession>
    <name>A0AAD5U6Y1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004187</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Y1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000014">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049898">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF41">
        <property type="entry name" value="BRAHMA ASSOCIATED PROTEIN 155 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52032">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="9">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="7">
        <location>
            <begin position="566"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="818"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="8">
        <location>
            <begin position="824"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="294"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3226769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1073" mass="122943" checksum="2F00C4D5FF5F23A5" modified="2024-05-29" version="1">MDLKKNILEISEYYNLPATISNFENIRLKLLKDFPTYTPPSQILTATIASLVQFQNKLLVKPKKILPFYKDSIKKRRLLPIPSKIFKNQNTIYLVLNHILKTEKKCPDFSDESNTDHFFNLLRSLWTMLETHIDQKTLKPTLTLPNIAFSEEIEEFILNNPALNIRKNGPGRVSKKMKMEEAERRKYEIKEVAENLGATIVPLTSNEVTHILMPSKDDNTYLFSSNRPDELANVYYRTLDKASGYSCLHYWYTPDSSDIWVADNPEILKPENEEDYEVDMTLFKLNNKKNEKINKAPVVSNVKKGKNKKDSDEESEMLNESGSETSNSKGRKKSTRKPIKKPAIVSSSDDESNFGQGSPKSEDSDVFVEDVDSGSAFEGSAASVDSEDSVDEDIDPKIAALDEEVDEEDRFIPDDDVILRPFERRRRESDDEDDGLMEPVPEEAPIEVIPVIELVDLDKKIVARAKKNEFEPLSGAILKNISITNPSCGWMNHYIQNEGSLPSVHELVTAQQSKSEDASNDIKMENSNMESKSIVTQEFNGQSIHPAILSSSLNNSNLDTFTWSKEIESLKPTWFNFNLVHIYEMRVFPDFFLDDEYYAEGENIHREQRHPLKTPEFYQNVRNVIVCAYQKDLVQYMSCLACLPFVSNISQKMFNQSYELSFEDLIRLHSFFEQSGLINNAVLNLDNFREIGTFVEIKESIKTRAALLEDKTLEKRENSRGRNLKQWEVFVEDLTADSSVTKKLTEVVSLEEALNVPSKIQGVEYQCFVCSQFAYNLRYRGIYPKTLVLCPDCYKEGIFPSCMKGSEFVRVEGPVGITDPYKRPDWNDDELLALLEGIEIHDENWRKISDYVGTRTVEECIVKFLKIPIGETEKWDSLLRKRPKLEAVNFTINNELEKEENLQNNIALSDNTLTLAAEAGLEKEFKELEYNGDNNESKVTSMDIENLKKLPGLEELYEIFAASENPLTSFLSIISTCLNPAFASSSSRVVLNFITSYFAEESNLSFKGEKYDLRKLNKDLLTYAILGALRESIICCEGEEERIKKYMKLCLELQLQLVEERISCLEKINETLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U710</accession>
    <name>A0AAD5U710_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein unc-45 homolog B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_004171</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
            <location evidence="1">Sarcomere</location>
            <location evidence="1">A band</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Myofibril</location>
            <location evidence="2">Sarcomere</location>
            <location evidence="2">Z line</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Perinuclear region</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U710"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024660">
        <property type="entry name" value="UCS_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994:SF1">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11701">
        <property type="entry name" value="UNC45-central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="8" id="KW-0221">Differentiation</keyword>
    <keyword evidence="7" id="KW-0517">Myogenesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="UNC-45/Cro1/She4 central" evidence="14">
        <location>
            <begin position="302"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="11">
        <location>
            <begin position="585"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="536"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF11701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3226753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="879" mass="98851" checksum="1BFCD2E3C738DD12" modified="2024-05-29" version="1">MLNIDADLDPEILKLTKDLETLEVNPETLLKRAAKYKNLNKFDKALNDVKTALSLDKSNLEAKNFMFSLLKETQQLKEVEASKNSVKSLLETISIENAPLEDRVESARKLLYLINQNEVEVSRNITQSGGITPLINSYMKDLESNGISEACFQNCLLTIILLSSKHNELNLKDFLTTLNRSNLNLLFFGSSEKKENFVYSIASTKHFKMVIEVLSLLCNFKFFNLPTNETTLLMNVQGIILENCLHVIKLIFKNKKSEELTNDSQDLELKKITLSGLMKILSQRSVCLNFIESKDLNFVLSLSKIEPVKNLIPLVLSRLFEQFESEENGNKILEGRLSSILNSWYKAGNSQDTSTALLALSAIFQAKPLVGSKILQSPGMIEEIADALEFAKEAVQLATLEALTSSCTDKSCRTLILTHLEVVLKNLSKSNSNALKTLASSILIKASTDNIAMQKHILENENALKNFIESVIKNASNSNKSERFLSSIESLAYLSIHTQIKEKLCFDKRFLESIFSLSSQNDNTLRYGIAMILTNISAYKKRLSGEEEQVKKLRELAKDKEVEIEDPKNSDKFVEKRCEFLTKSGVVTCLVKLSKTTSTNIKDIVAQIFLNLTTNKANRGLVVQQGGVRTLLNLSKECSSEFIPIAAQSLAKIVITTDPNVAFKGELKIELIKPLLDLCNGNDQLQQFEGTMGLTNLASTEDRIREIIVSLKGLQTFEMLQFSDNEMIQRAATEMICNMLFNEKVFKHYSERSDSQKLKIFIALSDSENFETQRAASGCLAILSSNEYCCRFIGESEKNIEIIIRLCEVGVNFELVHRGVEILKNFCYYEDLGKKLLKLGVVDLFRRLMKCEVKEIAVIAIEGITLLKERFATAPSLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U712</accession>
    <name>A0AAD5U712_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation factor 1 alpha-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HBS1L_1</name>
        <name evidence="13" type="ORF">HK099_003863</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Dom34-Hbs1 complex, also named Pelota-HBS1L complex, composed of dom34 and hbs1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U712"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990533">
        <property type="term" value="C:Dom34-Hbs1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002184">
        <property type="term" value="P:cytoplasmic translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16267">
        <property type="entry name" value="HBS1-like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04093">
        <property type="entry name" value="HBS1_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000020">
        <property type="entry name" value="Translation elongation factor EF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000204">
        <property type="entry name" value="Translation elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="259"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="180"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00063537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00074866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3226911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="699" mass="77528" checksum="BAE5A272369B1660" modified="2024-05-29" version="1">MSRHRNVRNMIEDDFYDDYDDNSDFGTSYEEYGASFEGHEYLYNRNQSDIQHNSAEEKDYDDNPEGSEILSKVREITGNQFSDQEIKSALCKFDYDINKTVDHCDAEEKQNRGPTSTNDVQISNFNEQKKPKVKKKPVSGAINSTILPKSNAEIDMESLGFSLEKEGILATKILPQPQSMKKSSSLSSLLQQKDNLSSAPTMERSLSKNGSRTGINNSLTSLQQSSSSPKPFKKLINVEKELEVLKKSGVKASLNLVVVGHVDAVFSHIFAKGKSTTMGHLLYLLGEVNERVLKKYEKEAEKMKKGSFSFAWVLDSTQEERERGVTIDVAINTFQTKNLKFTLLDAPGHKDFIPNMISGAAQADCAILVVDSSTGEFESGFELGGQTREHALLLRSLGVVQIIVAVNKLDMMDWSQNRFEHIKTKLLQFLVSTGFHKSKINFVPISGYQGENLVKLSNPLLKSWYKGLTLCDQIDKFTVPERAIKKSFRMSVTDFFKGGLGVGGSGSVSVRGRIEAGTIQIGERVLVRPVNVYGIVKGIEVGDDNPKWAVAGDSITMSLTNCDETHFTTGSVLCDPATPIPVTSYFRAQIVTFDLTRPLIGDDLILIQGSLKEECRISKLVSILNKSTGEVIKQNPRFLQKHQTAVVEIKVINKAICLDVFKESKELGRIMLRLGCNSVAAGIILDILEFQKGGEPETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U773</accession>
    <name>A0AAD5U773_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Dynein heavy chain 6, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">DNAH6_3</name>
        <name evidence="20" type="ORF">HK099_003871</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000005">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000006">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000362">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF68">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="8 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="16">
        <location>
            <begin position="2"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="15">
        <location>
            <begin position="267"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="17">
        <location>
            <begin position="626"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="14">
        <location>
            <begin position="1094"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="18">
        <location>
            <begin position="1244"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="19">
        <location>
            <begin position="1389"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="479"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3226919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="3600" mass="410581" checksum="5F02A2EF14E1A543" modified="2024-05-29" version="1">MDAQQHVTRISRIIRQPRGNALLVGVGGTGKQSLTRLACHMSDYQCHQIELTRTYGEIEWKEDIRKLYRAAGLEGKNIVFLMSDTQIKHEVFLEDINSILNSGEVPNLFEFDERERILGELRQVCREKGIADDRDSVYQFFINRVRDNLHIVFATSPVGDTFRNRCRMFPSLVNCCTIDWFDEWPDDALLSVSQRFLKYVDLGSDDMRDRIAEVCVNIHASVGETAKKFYAELRRRYYTTPTSYLELINLYISMLGEKRAELGGSRDRLRNGLNKLTETNELVAKMQIELEQLGPELKVKAQDVEVLMVKIAKDQETADGVRKIVSEEEIIVRAKAIETEAIALEAQKDLDEALPALQSAYKALDALEKKDIAELKVFSKPPDAVLMVLESVCILFKVKPDWDNSKKILSDPQLMKKMTEFDKDNIPESVSKKLRKYMENPNFTPEAVEKVSKACKSICMWVIAMDIYSRVFKEVQPKRKRLEEAQATLEVTMAKLKEKTDSLQEVEDQLEKLKSTYDSSVASKKQLSDKMEETTRRLSRASKLTSALADEQIRWTESVESLNFQIEALVGNIFLSAACVAYFGAFTTVYRKYLVDSWIQRCLDIGIPVSQNFSLYELLGDPTVVRDWNIQGLPADQLSTENGLLVTRGRRWPLMIDPQGQANRWIKAMEGTNLKIIKLTEAKFLRSLENAIRTGQSVLLEDVGEQLDPAIEPLLLKQTIRQGGRLLIKLGDTLVEYDRNFKLFITTKLANPHYLPEVCIKVTIINFTVTSEGLEGQLLADVVKLERPELEEQRNSLIMNIANDKKQLKDIEEKILKLLFHSHGNILDDEELINTLNQSKVTSAAIKERVVLAEQTERDINIAREKYRPVALRGSILYFVIANLAEIDPMYQFSLKYFKILFNNTIIESEKSDDFQTRLDILCKNTTFNIFSNVSRGLFEQHKMIYALMICCEILKEQSLILNNEWAFFLRGGNSIRESKETHKPQHRWLPDNMWKNCVDLSATIPEYSYILEHISSYPTEWEQIIESELPFMEPIPGDTTGQLTDFQRLLLIKVLREEKFTSAATEFVKRNLGAEFIDIPPLDLAKAYKDTTCRSPLIFILSPGSDPISSLMKFASSKEISMQERLHMISLGQGQGPIAEELMKNAIHSGDWVFLQNCHLAASWMNRMETLVKEYSSTETEINSNFRLFLSSMPSKVFPTSVLQESVKVTNEPPKGLRSNLARSFADVSKDLFDEHPPQGVKFRKLLFGVCFFNAVIQERKKFGPLGWNICYDWSNSDLEVSIIILRNMLADQTKIPWDALVYLTGEITFGGRVTDDWDRRTLNSILNKYYTPEILEDNYYLSPSGIYVAPADGDLSSFKSYIDSLPFEEEPSVFGMHENANISFQLQETRRLVRTVLDVQPRLATAGVGATSEELVEATASAILEEWPEPIDLDISDRPNSAGSNNEGKNINVLAELFKKDETGRMVNSLSTVLSQEVYRFNQLLSIVKICLETLVKAVKGLVIMSAELELVFKSLLINEVPASWANAAYPSMKPLASWVKDLHERVAFMHDWSLNGQPSSFWLSGFFFPQGKIKKKSCTFNSPQLGFLTGVLQNHSRKHNVPIDSLTFNFTVTDISSEANFSEKSGSGDNISSISNNLDPEVDGVYIKGLFMEGARWDFEKYVLQDSFPMEMYSVMPMIRFIPTQVVEFDNETQYKCPLYKTAARAGTLSTTGQSTNYVLAVYIPTNKGSDYWIMKGVALLVECIEVFEFNLKFGKYFCTREIWMDLKLKCLHRPIQHQAVSDLSFHEITIIWSTLENSSDPFLMFAICKKILTFVKHASISCEVLFEILKVCVFQELSTDVDSELFFCKYANTEHYNTALVRQHPLVVLILERPDAWPYVIHQLRDFFYVRYPVEDPRNYKFNLFGFRMLLPFFNFLFLFKKEEVDNLNLTVGKNSVLQILSRDIFYEIHNVENYMFRDFSKVVLDFFMLIVRLNPPTKNVCVYSQLYVETLSSCLMLIANKIDSFLFYEGFFVIMSYVLESKLQHLYIGNLLRALDNLSTAMRIFQIDTNELWLLCNSVAYLLLDVMDCDEERGFILKLLNNVIDIVISQSEVENNTPSVILSLCVIPLLQILSDGGDVKQLEVASNTLSKIEEYVLGGSKHNMETKNFEIRSPINSSWPLQCIAQFLSLTVKSVSKKPCEILLSRLSLVNSSLTLINLSPFLFHSKVEHQLETLIFLNKNSNNFPPYSLFSVYLYLSKKSQNPHLQHLIFTKLLPNLASTSDVFPTGSVLQIVMRLLQADSRKQDCELFKLGALSLLQLFIKQPRIWVRLKEILMKWILKKSSINFGHTKNFETDLTMLGILRVISKRAEYGQELFSIYVSYIEVMLTATLGSECFEFIDASLYLIFQGVRNIIVNMVIDVRADTETYIQFRQDALISIISTLDVSKTIDTELPYSLPYFKLNGGGCLPFIFRAASCFPASDLYPFFSCPVKLVSVVTTNLSSNTRFTKEETADFNRELILTPVIGSAELLAKLISSEIKSMRKSVFKGVASNSWTANKGTVKEEKDNSQEAVLKAIGELSVSINETLDSGKLFPGLKATAKGGFAAVALNIRYPSSVNVTKSFLQKGGIPVLIYRRLELLIKDLPTWSITDSLFTRLYNINSWSNFWENSIFFQISNLQVDGKRADAKIIAEEWFLIFYNYLFEHRLESSKTPGQIFNTLLGISGLIAGSSIELIEKFLLEFNRVSNPISDRSIFGDFFANEEVKIGMLVAIYSAACALHVTDHILLKKVVRFFIDLNKEEHDDELSWLNFFSRYGLSLILKNLIILVHPSLDEVGGMILENFEDEILDLNSNQPSTQFGSIFGIELIFNLLLNQENMETAFKNNMESFFKKIIEFLVDKFYNFEVKELIFRSFKDKVFIISCLWLLPCVINTEFLHKNSNDVFETWRFKLSFLEDMLKKSKNLIDIEVIHEFVLVSKSKLLRANDADLFNQFICDTTEEILSGVGVNHTKYSTLAVFPYLLGIDPLTSHYITNNSFELVLKAFHCISSFLIGNDPKLSRLCGTIIGIIISSLTDFQESLLARGEGSFVNNGLTNNTVTNLQLENSSLNSSIAKKDPSNLKRLNISISYLRATFDELSSEHLAVTGAELLMKTLLLINIPFPLTNWSFTLHSLKKKSFDLSVLTFVFSSNHSSIEEARSLTDFFVHALGSTLTSATRRQTQFSAPADFFWDLQAENSESQYIKDIIVSTVGIGKLLKLAGLRTCSMERNDLFPNVLSASTVLNIFEDYLYWLFSSDFANEKLQINFFATLLPFLFWENRTLDSNSLRADLIKLIFQIFMKLPDTASSELITSIVLILPSDESSCNGLMEYLGDMDVVKSDKGCISLMAVASMIMKHGGCSSLLITLSWTTVLKKPRDKCDLTNFNEIGNSLILHILKERLRHSNLRFSTILRFLDVICGLDEKDAESGIKTDEKCKIKWIINILDIIIYHSAKTISLKSENCQLLAVEFEWNVLLPCLANVWWGSCRKQSRLILWNLLQKGTKTKMCNEDFGAILHNFNFIMFNEFGKELKVADRNMIAKRLQKIIDNLTSFNKDSSKKLIDSINLSYIKFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7H3</accession>
    <name>A0AAD5U7H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">39kDa subunit of ndufa9, NADH:ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NDUFA9</name>
        <name evidence="2" type="ORF">HK099_000840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7H3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="314" mass="35327" checksum="746D1927C869DB3F" modified="2024-05-29" version="1">MIILKRFKSTLSKKHLNPILQREGTGGRSSISGHTTTVFGSTGFLGRYLVNNLGKRGSHVVVPFRGTEDEKRHLKLMGDLGQIVPLSFDLRNDERIIECIRHSDVVYNLIGKDFQTKNFNFQKVHVDGARTLAKLAKQCGVSKFIHVSALNADPDSKSLFLKTKGLGEKAVLEEFPEATIVRPGYMYGHEDRFWNRFGFYTKWSPIGMPLINKGKTIIRPVYVGDVAAVLAQLEEVTFSNKLVELAGFLAGVAERLMFNPVATADEVERYFVSDSLQNGSLKFEDFGIKPHTVEETISRFVRMYQSEDHIGIQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Z2</accession>
    <name>A0AAD5U7Z2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquinone biosynthesis monooxygenase COQ7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004888</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000036">
        <property type="protein sequence ID" value="KAJ3226435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Z2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008682">
        <property type="term" value="F:3-demethoxyubiquinol 3-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01042">
        <property type="entry name" value="DMQH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011566">
        <property type="entry name" value="Ubq_synth_Coq7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237:SF4">
        <property type="entry name" value="5-DEMETHOXYUBIQUINONE HYDROXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237">
        <property type="entry name" value="COENZYME Q10 BIOSYNTHESIS PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03232">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3226435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="18150" checksum="24CF0A7C58EE1A7A" modified="2024-05-29" version="1">MNKKLTPKQIEMIHSMLRVDQAGEIGADSIYKGQHYILKNNQTLGPLIQHMWDQEKHHLSTMNKLVAEHRVRPSLLEPVWKTAGFALGTMSALLGKESAMALTEAVETVIGEHYNDQIRELLLIEGVEEIDELREIIKKFRDEELEHLNLAVDNDSKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U820</accession>
    <name>A0AAD5U820_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RNF14</name>
        <name evidence="15" type="ORF">HK099_006023</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the RBR family. RNF14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U820"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20341">
        <property type="entry name" value="BRcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23820">
        <property type="entry name" value="RWD_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000416">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RWD" evidence="13">
        <location>
            <begin position="3"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="162"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="166"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3228143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="438" mass="51220" checksum="7B644A46C36F5ABD" modified="2024-05-29" version="1">MDDELLAMKAVFEEDFTFEISQKEDSLATGTFTVHSDRLENDLILKLGNIVAGNEYRVNYLPPITIVFEIPANYPQNEPLKFYCSSTWVPNLTLLKIKKKLLNVWKNLKDYCLFEYSEYLKRDFLENLDICDNILCVNGSEGLFENIILYNKERQQKLFDEDWFNCGVCGEEKKGIFCIMLAKCKHVFCKECLNEYFTLLITEGSIENVTCPDFECKRIASKRQHKFLSDIVDFDMKQIVEKDLFSRFKNLQEKKKLEGLNIIYCPRIFCQSPIIRESTDEKLCICSNCKFSFCVHCSKSWHGYTNYCQIRNLESLVNSYLSENSEEKALIEKQYGKKNIEKIVFRYQEELKNKEWYSENSQCCPSCKAAIQKSEGCNHMTCSKCNTHFCYRCGNLINQLSPYAHFNDKNSPCYGKLFDFNSEGNEEWALGEFDAEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8M9</accession>
    <name>A0AAD5U8M9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8M9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="27825" checksum="B449B4EB7BE21289" modified="2024-05-29" version="1">MNPLSEINNSKQLPFLLKVLLKIWVCSAPLMTLLGVLFGNKILELKNFDQLFKIYDFLYFQLFKNKFADYEQSPMSFVKEKYFEFKSSPDNLEKKDKDLKYVNYDMKKINKNMKNNDFKTKDLKKRNINFFNIKVNDELKYLTPEKIKNFNLNNIYKITANETEINSTSKIKLNNFQSDGTKLKVKLLDTNVEEMKFSSCIKDSIQDSAKDFESELQIIDDGNSDMSSVALAAENIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U989</accession>
    <name>A0AAD5U989_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein fam49a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FAM49A</name>
        <name evidence="6" type="ORF">HK099_005884</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CYRI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U989"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039789">
        <property type="entry name" value="CYRI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009828">
        <property type="entry name" value="CYRIA/CYRIB_Rac1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12422">
        <property type="entry name" value="GH09096P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07159">
        <property type="entry name" value="CYRIA-B_Rac1-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYRIA/CYRIB Rac1 binding" evidence="5">
        <location>
            <begin position="24"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="315" mass="35136" checksum="837C8BFD7A7CC53D" modified="2024-05-29" version="1">MGNFLTLLKGGSSQSLEEPPYQLEVDLDAASPTPEETNFYNYISDVIRPCQANLESLRTYPGCGDYIRKAISSPSRESENEAWEVVLPAVAKLRQFYEMALKLDEAFVKAIQFFAQGSVLENLEKYQATAKKLSEILYICAQFDEIKISNPNIQNDFSYYRRTLSKMRMVNPSPQNLVVNDELANRMSLFYAHSTPLTKSLIDSAQGLGSKGVPNGEICDLFAILAAVCYFTVQKNPQAPADYFLRTMVMSIILYDHVNPQGAFIKTSTINMKASVKVIQTRGGSISDSLLGSLKYTTIHLNDETTPKQTKALFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAL8</accession>
    <name>A0AAD5UAL8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coiled-coil domain-containing protein 87</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CCDC87_2</name>
        <name evidence="2" type="ORF">HK099_004797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000035">
        <property type="protein sequence ID" value="KAJ3226487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAL8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037383">
        <property type="entry name" value="CCDC87"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16078">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16078:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="984"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="984"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1058" mass="125023" checksum="6339A675D5833B20" modified="2024-05-29" version="1">MSVENQNEWLCESESKQMAKILLAELATKFTRIKDFTVKTFTPTQNRIFILTVFGKISFIKDEVLKICQKKKEKMQKNGIFDEENNNSRIRSIFQLELSKRIKKDLLINESLQEVKYRIKNKFLNSEEDVVTEKSDVEMFKDTFQKMIKVTNPTVEDKYNYSDIQKEKQDIKERYVLDDTEEPDALKLFPNFTAKFNKFANEILKDKNKENCALHSIRKAKKKLKNFEVCNLDNSHQNSLKDWEAMDSEFYKDDVLEISNEEKPKNSFYNFTDPLLSAHLENPLATLNRSSRRVKEVNSVCFSNNKRYLIPNPEITEKIKKMKLDIFDIQQEDEDFNDKLFFDDYLANESFKNLPSKRKLKHGIELDLSFFLEKNLPGTTICDKENFDELVKKSNELEDIYEMVLGTMDTDIIFREEALNEIVVCPTAPSDPEVLINNLYSGFAENFDRRNNILDVKPADNDANYKLPPIRNKNQYKKQFSLNINKNNKKENDDNSEKPSLNNSIRLLTRKKGHVTVKADEFGDDRNKAMEKIISSKYGVLKYNYGGFIPKNVMPSSKLAKKNEDRKDVNFKEYLNYLRVRLTDFIFDYYIDKEEEDNRRKKMEIERKMMLKDEEEKNEYEKIKKEKIDKRKNMLRYQDGFWNAGYLQYMEEIHNRDIKMGQVKVDKEILKDLEFEKLKDTKVIQHKLMHDIKNKQQTVYSNEKDESECEGEITDNSKYIEENSIGRATECAIGLSNSAFFNSYSQELRQTNSASISLYSEDTEKCETLSNKEENLTTHERKPENNVVNIDKFLHSSNEESQDSYANELEKPKSPLRHSESLQDVDFIQKQLEKIWKILKMPLDQKMDMVVKYSSPKFAKDVKEALESWKSASRCIIKREILLKKIEKFEEKYCDPSRLFEKGGDLFNASKLIRIEECKNREHLLKELHTLDYQTENEIITIKNHLKETVTYCGVPYLLKMKKDYQEILADLCEKRAQAKEKSERRLEAKTSVGKDKKKIGLSKSTQQMEEEYLEFEKEDFKKKDSDGALRPKGEYHDINLSEFYLHREKNNYYENLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC40</accession>
    <name>A0AAD5UC40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC40"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="40807" checksum="3EB01C896BBB912E" modified="2024-05-29" version="1">MSSTQSQISFSESEYSLNLANTTSHLSIGHNIPETIHETLSPEEHEFLDSKFTRTQYLNCNQQVINNAKKKWFTLLGETDFDILSLYAVSKARTTMESQIYLKLLHRRLPVNHYHKETKVCGTCKVSDETIRHAIFECKSSLEFWNKISQIIPTILNLNKEQKSFFQEVSLADVVYLFPKLRPLLNKDQLHVLNVIHSVALWTIWRSRTNNYYCNKMGIDLNWESFTMRLKVRVELEYQALLTAENLNAGSHSFTYDHPLTSAPMSFDSNSSSPTNLCNLSVISDLEGLLSKSFEFSPLEPSNFSFSLKYSSLEELSECSSGNSKELKSVNSEFSKRWTNNVTFEENGRLIFSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC70</accession>
    <name>A0AAD5UC70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">THO complex subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">THOC5</name>
        <name evidence="5" type="ORF">HK099_004285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC70"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019163">
        <property type="entry name" value="THO_Thoc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375">
        <property type="entry name" value="FMS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13375:SF3">
        <property type="entry name" value="THO COMPLEX SUBUNIT 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09766">
        <property type="entry name" value="FmiP_Thoc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3228292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="553" mass="64161" checksum="37EFDA3D1F30696F" modified="2024-05-29" version="1">MVSNNINVEQRLDQAANYDTHQHSFQLVKDIQDAIINNNFVEADSLIIELVQLQRNLTMKNKYKKDETVELKNKNQIHLSELENIRYRAKFLQHELTETLNFETKYHLIKLLPLEEYLSISDDKETNQHRLMINRLNYELESRKKLREKEIKNKLIDNNLKTSKKVLQDKLEKIDAQIEQFIKATEDLQDTFGLKITKKHVLKKKGKFLPNKLSTMFLSLVDFDDKNEKVISIEIEGDQTEARSISNILKKKKEEKKINENVEKMDIDEITGGNDDVEDEEEEDETEINITKIHPLQVIVTLLKTGVKLVFSFLTESEAILVKPILTSNLEFIPSSYILDFDNSWGVYKKFTGNLEKISQNFVSEDGSPYLWAQQWTGDVSILPNCSNSEIFKVNTKTFDLINSRYLTLRMLDDQLKQLKAGNPKLQVPKSGNKFETTLNLQQNYPKVSPIWKIINFTSGQTSQNLHAMKNEALHFKKIEFEINIKIDKFKDIFDNFSLDLLLGYQLVKMSTCFENFIKHFFDGAGTNTSGDGGAGNDEADIEEEISKMYRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRR3</accession>
    <name>A0AAD5XRR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002123">
        <property type="protein sequence ID" value="KAJ3199398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052405">
        <property type="entry name" value="Mito_Transl_Release_Factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203:SF1">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203">
        <property type="entry name" value="PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="66" mass="8061" checksum="9BD7AE878C413DA7" modified="2024-05-29" version="1" fragment="single">GVITYRFREQDLNRIEARKLLKIKLDEFYNKENSISSIKIKKMQLKKKRKEKRSKEKYGANQKDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS65</accession>
    <name>A0AAD5XS65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_001981</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001618">
        <property type="protein sequence ID" value="KAJ3202132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS65"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="390"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="210"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="273"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3202132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="520" mass="56430" checksum="07F44FE2B85CD13C" modified="2024-05-29" version="1" fragment="single">MGDNSTTPSQCFILDSNSYCGPEYVGYPVLVSSFQNQDLLSTYLQADFVDAEKLSLLFSTNFGCSGKNLLQQVNNRRFHTSFQCSQIVNDAILQNCQFDSTKFPSVGPVLCENQCNLAVSSLKSIIENPEVCPLNETVIDARAQLVGQFTNYCATAKNSSASQGNLCVQGTPIENTKCGFINDAVALTGCTANPTDPCCISFLKTVPTSSADTNNNSTTSSDLSESSSKNANNGNPSSNGAGPGVIIGVVVGVLILLLFVVFFILRKKKNRQAKSISSAEQPLKGSSELNFRSTPSPAPSFNQNQQAINHASPPLPLPTPTQRSAADENPFNTIQQQPHNLQMPQIPLQQQQQQQQNLQQVSNNFNEQYGSFPPNNDQYGAFPTDAPKRKSTEMMVVVHPYYATLADELQLEVGADLILISSFDDGWALGMNPITGQQGAFPLVCVSKPDELIAKGFDRQSLSNKRNSTFVTEPTISNRNSSQIFDKQGLAGRQSGYSPPLPIQSSAKNPTVSQFYGEYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVS8</accession>
    <name>A0AAD5XVS8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaphase promoting complex subunit cdc16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CDC16</name>
        <name evidence="9" type="ORF">HK099_001867</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001579">
        <property type="protein sequence ID" value="KAJ3202383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVS8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="7">
        <location>
            <begin position="371"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3202383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="487" mass="56558" checksum="B7135CA1A9160691" modified="2024-05-29" version="1" fragment="single">MKSNLDRKKNSSSVSHTNMNVNMNNSTLFSKQQTKLTTKKFSHIEVNQQTDIKLQQQQQPNKNNNPNVLNQSHQPLNNLTNYSNKNILMILRKWRNDATELNLLSAASFWGNKLMTITEDPIDYFFQAKTYFQQQEFLRAKNLIVSENLSFKNLQFQYLTALCYSKLLKWDKVIEVLSKTVKGNFDNSEITENGIKIESAILYLKGRAFFLRNNQEQAKFNFKESLKVDVKNFDSLQQIIENNMLTGLEEKLLIESLDFSQVGEQSLFVKSLYLSMLKKYDQKENLDAVLTNLEIEHKLLKNVDIQFARADMFHSLCKYSKCYEITQDIIGVDFSNFQVLPIHISCLIELNLKNKLFYLAHQLADHFPSNAISWFAVGSYYMLIKKYTESRRYFHKATSIDPSYGPAWIGYGHSFSYEGEHDQAVMAYGTANKIMRGTHQPSMYIGMQQFCLKNIPLAQNFLETAYKICQTDPLLLNELGVLWYKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVX2</accession>
    <name>A0AAD5XVX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008264</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000895">
        <property type="protein sequence ID" value="KAJ3210364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVX2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3210364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="74" mass="8490" checksum="EFA7273D69508586" modified="2024-05-29" version="1">MRLKAEGIKNSVVVVGHKHPDPKHHTWQEVEDDTIDKHPVVRGTGGTDLVPFLKQMRDETLLAKCEVKKNYFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW01</accession>
    <name>A0AAD5XW01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-alpha-acetyltransferase 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NAA30</name>
        <name evidence="5" type="ORF">HK099_001406</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. MAK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001394">
        <property type="protein sequence ID" value="KAJ3203679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW01"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044542">
        <property type="entry name" value="NAA30-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="18"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3203679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="17103" checksum="52530FFA1AF1069B" modified="2024-05-29" version="1">MSEETVTKLTIGEKKEIKIVRYKDETQLNAIINLIENDLSEPYSIYTYRYFIHLWPELCFLAMYNDECYIAMLAVDKRYRKKGIGSNLIETVCITIAKAGGDEVVLETEVTNKGSLSLYSHLGFIKDKRLARYYLNGVDAIRLKLFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW38</accession>
    <name>A0AAD5XW38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000823">
        <property type="protein sequence ID" value="KAJ3211628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW38"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="28116" checksum="8210B637A4D88C1B" modified="2024-05-29" version="1">MYLVHIGFAYVIAFSGLACFITRIIPSIKWLHVWFGRCYIISMLGGTFTSLLIFNSGLPSGTIVSFIIVFFGLTFGWLFIKFHQSTLESNTLKQVEKVILNNPENFLDSLSLKNNGLDHIIYTEKLRLLRQKTFIQIVFSYKTAHALLMAASWYNIAGRIFVTRPSYEKFHCHTYPAYKFSPTGSNETVLLPASVPEVYNKLPWANNELGWFFLSSLGPMSFGLIVCVVYTFFRLKFSNKPISEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWJ9</accession>
    <name>A0AAD5XWJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002774</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000195">
        <property type="protein sequence ID" value="KAJ3222036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005078">
        <property type="term" value="F:MAP-kinase scaffold activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022018">
        <property type="entry name" value="GIT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039892">
        <property type="entry name" value="Spa2/Sph1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056439">
        <property type="entry name" value="VBS_C3G9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601:SF0">
        <property type="entry name" value="PROTEIN SPA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601">
        <property type="entry name" value="SPA2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12205">
        <property type="entry name" value="GIT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23742">
        <property type="entry name" value="VBS_C3G9"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C3G9 VBS-like" evidence="4">
        <location>
            <begin position="459"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="C3G9 VBS-like" evidence="4">
        <location>
            <begin position="607"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="C3G9 VBS-like" evidence="4">
        <location>
            <begin position="736"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="C3G9 VBS-like" evidence="4">
        <location>
            <begin position="860"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="domain" description="C3G9 VBS-like" evidence="4">
        <location>
            <begin position="1021"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="domain" description="ARF GTPase-activating protein GIT1 C-terminal" evidence="3">
        <location>
            <begin position="1174"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="568"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="266"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="576"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1290" mass="144230" checksum="F7AA95D05E1A3757" modified="2024-05-29" version="1">MSTSSNIFTMEQATELATKHYEGYRKYLQNHVSSSTSARRAAQMEKMTRMSNQELIVMSINVFDEMNRRVRTPQLLKLPPREDLSQKKNEERESLSVIHEKGFMQLTSDIKAQLEHRFPAVIQKFNVKYGIADDSQSKYTTRQSTPISVQNSARQSVSVNDKYRQSQIRANSNPISPPGSPMSPRRNVLNANENRGRSSTPINENYYPVEDTSLVPSQRGTSFSGRNRSTDRDRYIPQSPKTLNSRITTSASSNQMKQDFQDAQQNETFDKQKNEYEQMIDELKEKVNYLQLNNDKIIGLEDKILQQLREKQELNLIIDRLTQENDNFNDEIQNQMVLENDLRNEINSLVDELNSISNLNEELHGENSKLSNLNDELTKKNTTLNKLNQELTLEINQISKLNQELKTKLSKVSSDAVDSSKSLEREEKEEVDEGALSPAVSEKNRKASLALPSFQETAKDKIDEYFTSMNNFLNVLNTGSNKAILLPMKPVMIACRELLLASENFEKQYNVNSTEVNSAKESLSFSLGELVNQAKSYATSESPDKISVEVNATKLNSSVSNLSAAHGKQELNLSSNDHDGKNSEDNTEGTDDKTTEGKVNIIVREPQVIISDQKISEYNKVIASLLNLARSDNNKSVVVAVKQVMITCRQITQDLEGGNFVDSEDVNSLKGIFSLKLANLVEACKKHATTNESQLPVIEEITLGLNDTILKLAAFANGTEYHPNSSSEKMDSNVVIISDESVDLYQKGITKLLSLADENSKNVLVVMKEIMLACRSITEESHHFEQTLPTENEEIKLCKDKFSEALSVLAVSAKNHATSTNSPVALLKDACDSLTLSVKDFARVVNSVANLPENLIAVSSTVINQSTLGSYQAALRKLIHCTTLENRKNVLVAMKDVIIICRTITQEAENLTSDDEELSISKTNFSNSLANLVAILKVHATSQEEVKTKEIEEATENLTKAVFQLAHVLNGGKSNFYYEPVKRIVSMQVNNQNLVKDGNLDQNNELQHEEKDLPKQTFELVITQERVDNYQSSLLHLLKTARGSENKEVLNAAKRLMNSCKDMLLDCENYENSKDVEELDLTDLKERFSHALSTLVSAVKTHTVLSTPMNVLEAHASALTTSVFDLVDYLNYQGDYEEGDATFEGEAANSNLEGLEASAGQSLTIEQLAAHLSTHIDLVVQAVQTLLTVVRRNQSFEDPSELKDSVIGITSIVEDISQVTRQTLLNNVTSELKVKGEQILVDLSETSLTLIKLGTIDQVPQEDVKRLKQELATLSYDILKLVKALLNLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWL3</accession>
    <name>A0AAD5XWL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl hydrolase family 13 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007066</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000657">
        <property type="protein sequence ID" value="KAJ3214003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042283219" description="Glycosyl hydrolase family 13 catalytic domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="3">
        <location>
            <begin position="345"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3214003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="609" mass="68102" checksum="2DBDF67CD1B0AB68" modified="2024-05-29" version="1">MLSGPLFFILVSVKLVSALQTTISLANPRNVNAKNVFLVGTFNNWQSSANPCTFNNNIWTATLDLDRSLDHQYKFIVDGSWVLDLDAQKVNDGKGNLNNILPSIPTPPPQPQPGTSVISLDTPRSENANKVFVVGDFNNWSATSSPMTKVNNKWTATINLDTSKNYQYKFIIDGQWTVDSRAAQINDGKGNINNLLNATTFPQSLPGCQTWDGFEYCVWDRQTNLPDSVLERKWQTPAKNSSSYVNTYQSYRDLTGFASIKYAPNHLSAVVTVNTFTRDPNAVLLVSFNNQQPTASKTISLDSSFKTSLPIKIVIANTETTLVLEPLNFFWQNTPVKSNYNGQKGAIVELLGWPYKDIAKECVFLGKAGYMGVKIWPVNEHVFNDKSFERGKTEFNNWYYVYQPVSYRLHNRFGTREELREMVQTCRENGIRIHTDAVLNHMTEGYNSINPHRDPGRQCSKTVPFSATAGSPFFTHANTFELNESTGKRPANEYPAVPYGPEHFHCERENDWVTGFGLQFGGIEGLGGLVDLDTGSPYVQGRIADFLVDLFSIGISGFRCDMAKTIGPNDMANIFAQVKIRMGGNLPGDFITWLEINMGNEKDLLACNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWP4</accession>
    <name>A0AAD5XWP4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006948</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000635">
        <property type="protein sequence ID" value="KAJ3214274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.240">
        <property type="entry name" value="Transglutaminase elicitor, body domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032048">
        <property type="entry name" value="TGase_elicitor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16683">
        <property type="entry name" value="TGase_elicitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042125705" evidence="3">
        <location>
            <begin position="19"/>
            <end position="1748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="708"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="786"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1016"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1107"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1527"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="796"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1018"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1129"/>
            <end position="1154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3214274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1748" mass="197412" checksum="2F83FA14D5862B14" modified="2024-05-29" version="1">MKLVPLIASLSFTSQLLSSPTSLQDVLKNIKKNLDVAKTDKSAPFPGRGFSDNAGDDIDGELDLTWQEGVKLLQDVIDTPFELNPDKLPKKGSCENLPWPSDFFPVMRDGINSHFNDKNNISATVKYARAFDMNEKELEDIVSAAAGIDRQVTLGRTCKEDSDCTEYKDLSVCAKRFDSETGRNETLGECIPFWFGLCHAWTPSSIMEPEPQCPVTLNGTEFGIMDIKALLIQSYDATNFSTVFTGRRCMDTSGIKGAPALDEFGRFNDSDCKDMSPHFFHLAMSNMVGIHGKSFIIDITADIQVWNQPIAGYEILSEKSLTKQEALDAVFPGIPMEETGFNENATSFTQFEMKFEYITEATSSKPLVSTGLVNQFMVPLTVNYVLSTDKDGDIVGSEWIGSSKVNHPDFLWLPTSAPAEDSKSAGIQYSNVKLLSQMSQECLELFDETETLLRPSTTPNKSLRNVNLSSVAIDSPLEYKIPDLNSIKNNGFEFPLYCQENFENQENFSFDIETKDNHFNKEESFSSDLQLDTPPIRKSPRLLNNSQKFENDNKKVLKLKNSRDSMRSPSVSKEVTHISQFAKSPRKQVKPGRDSIAPFFEMKSPISPTRSSLRYISSNMTNLANNDDEDDEDMSLTQSTNENVSLLEPSIDFGSVFGDFDQIVDGTSKKLSDLVVKDNVEESEEDDAMDLTDVFIRTRLSTSKSKKRISLFSESKESESDMDLTDSNINVNVPGEYNLTKLEDDGSSSNEDDDKQSTDTFDGKKFKNILKDCVLVNQNISKEVEEEAEEAEEFTQRSNSQGNSFSNSQQTTTNSNNSQHTYSQVSSVDLLGETSISTEYLNGEINIELNMEANKEIIKKNIEINSNTATYNDQNSECGPSPKRIKINNNLQTIINATVDEELVIDITFDDQNPANKNSHSAGTRMEDLKWNIENENVTPKKKIIPKEKLLLIAPPIINLKPPTPGRLLQNSVTKRRTTINPGPRLTNFLSQQQELKTNRRNTLGSNEKKIKLEMDPTTASLSEGSNNEVDYEKTTPRKQMVNIPKSEITPEVNGNNEETLFTPKSVKDSNSKFNFTPTKKLSSKFFSPSKIPSPVKKISSNSRDIKLTPKNSHLRKEVEFSPLQKSTAKKEKTKDVVTAKGKNDQKKKPEKSNISKMLAEGDSVDKYLDQCTKIVNNSGRLNDAAEVFDINQADSPFKKSTLTKRDIDPYNSSNQINDNESLNDVISPFENSKIAKLNPINGESSLINPKKFGYYNSALSSNIENDELNFSPFKKSTLIKRDDSFVISSQCKINSSEGTPRKQPNSLQCKVGQTIGQDSEINDDLMDEKPINLHFDDDEMVYTSIIDEAKELHDIEEFNKYTGIIFEIDNFPVPEIKTVDKLNKANYSKEDKLKALMILAPEAELYELQSLKYTKDFNLLFSEKLSLQWCIGSLKELIDRFNSNLEFIFKVSIKYSEWLNSNGIKNEKDAVLVESRLNELSKLKETVEISISEYSNCNKAAKETYESEVAEKNSTISELTIFSAKNAKLEEDLRLVEIQNLQLESDILELREKRQNIVLEIENSEKICESNILLDSKQIAEYQEYSKRIGMCENGNDIRRVLKQTQNLWYQMKLIHSEVEKLSEDILIEYIGPEKPLKNATNSSWQKEKPVFGVEVQFNNYSLKSRFKLKIWLIIIKYNDEIILSLTNSAASPQSELKVLFPYQDLKFSFENCFGKFTFENVSKLFKSVKKEYGVIENICKGLSSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWR2</accession>
    <name>A0AAD5XWR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GCN3</name>
        <name evidence="10" type="ORF">HK099_002020</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001632">
        <property type="protein sequence ID" value="KAJ3202038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWR2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1070">
        <property type="entry name" value="Translation initiation factor eIF-2B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051501">
        <property type="entry name" value="eIF2B_alpha/beta/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042528">
        <property type="entry name" value="elF-2B_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3202038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="222" mass="24673" checksum="ED44B173CA21EC30" modified="2024-05-29" version="1" fragment="single">MKKTKNPIAVQAGCDFFLRFATRIQLQNEENLDNMQGHKEQLTAISSLFVKNSFLRRDAISEYALKFITDDATILVHSYSRVVMQLLLKAAKANIRFQVLVTETRPSSSGKRAVDELKHNGIPATMILDSAVGYFIGKVDMVLVGAEGIAENGGLINQIGTYQIAVVSKAANKPFYVVTESHKFVKLFPLNQYDLHGSTPKTSVAPLRRKRSHHIDVDLING</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWW1</accession>
    <name>A0AAD5XWW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001496">
        <property type="protein sequence ID" value="KAJ3202953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWW1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="662" mass="76959" checksum="2268A6206CC74062" modified="2024-05-29" version="1">MQIEETELMVSKVTTIHNKFDKSKYELSFPFFDLNDENEIALLERDDILLNINEEFQYRFKSPKYVPFIISTSRGMGKTFLLKKIGMQKVNRELQNEDILEATKCGRILSFDFAKYKDAISDTKDVFSFFTRLMVYFLCRLFHGSKVDGINFHIIEFRNILSYNATQNEFKLWLKNFLSVAAEEMMDEYIRLTNLAFGINSNVAPVFLLDEIQTLAFTSTRVVSTISSKGVSTYHTQLTLLLTQLAGKHRPLCICSGTNNGNIISITEKSKIVPQLLRLKPLVTSSMEYWKQRSEYWGKTFEIFESDMALIDSLICGTYQIPRFLSIAHDVWYTSKLNSYITNREFVTLTFEQKVTKYYDEIPNMLMSNEYTPEDLFHIFIACGVHWEVKDEYSYVPGTQIQWKTLIQNSLIFPYTRNCYLIPFKLIWNPHLSNLDLKEITVRKDDIIRYGMSKLTDFNLENLFLEYDKLSKYNLYNFGMAYEYLLAASLAVKYYLVSITRKNLESKITFSSIYDFSSNFDFKEFDVYINFSKGIISSKKEVFVDEKDLSNAIYHNNLNHNAHHDLILPAKKDEVRFNVAVSVKSSAVRPKRSDLKSQCLEKNSKKAVDILYWFYLGEEGPLSEKVNGAKVIYLDGRGCCNGLAIDMLVFSKKLKQLNNSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXI7</accession>
    <name>A0AAD5XXI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000399</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001093">
        <property type="protein sequence ID" value="KAJ3206883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXI7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000074">
        <property type="entry name" value="Angio-associated migratory cell protein-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="704"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="747"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="796"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="828"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="917"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="958"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="1000"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1026"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3206883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1026" mass="116699" checksum="CB8C2733212D201A" modified="2024-05-29" version="1" fragment="single">MITANDYKNLLNPNGNQDNNIEDAQEYDTNELDFKFLNECNDIKKLKSLLHVLQTKEIGFDALETSFKKKIAKLEGWNEERDEKKESFLDLFSFAEEQKKKEKLLIEESKKKKDLKKVEIKTKKKNFSTIAPAINKIKEETPKQKVDEVNEAASSEEGKKMKETKKSKKKKSYREWDLFNVEEEIEKNENIKFEENSGLNFDANPMSIPKLSKEYKVQVELESLSTEEKIKGNDSFRSKDYEDALAHYTRGIEYFPQPTLYSNRAQTHLLLKNYKKCEEDCNVIFSNFNIEEIDKKILLKTYLRRGRSYYCRGEYNKSLEDAKSGQEFNLKHFNGLNADLNQLKIDSEKKIKDLYLNVKTDNYNQHNLKEEDSDPSKLFNLFGKEDETTKKKSKKFLIEEIDEIEDYEEENIFAADSNDHKVEEKNILSQGEKECQNFLNYETNFNNTNASFIEEIVVEVEKKVKTVAAEVFCEVNESGENSESNFAKVIKTIQTAQEKEYPVEVEVNAERKHFSLESKDENFMETTKEAITHDINDIKKNCYDEIYLLGAVIDLSSNTLKTDNITESDGSSTFNNNNKIESKIEENLNDKKFTENTNLELNVKPTQQIVNEGIFNYKESIALQSKIVDEINISLFNENTEKNNNENEEEFVDETDVLEEVPVDTHETHMEEADDMEANEVEENDEVRNEGENVQFEDDSVQGFFDHHEPVYSLDIHPTQQNVICSGGGDDKAYLWRLDNGEKIFELTAHSDSVVSVAFSVDGQYVATGGMDGKVNISTSVSGKFIGTLDGPDEIVKWHPKGNVLVAGSADGSIWMWSIPNGTMMHVFIGHGGPVTNVQFTPDGKTLVSSSEDATIISWDPKTGSLIHKFTTSIGRFHTQPITTFAIHSDSQLLVTGGVDSVAVQCQLGTGKIIGPLQAHTESVESVDFCDVMPLVATGSVDGLINIWDFQTLRIRHTFRHSEAITQIKFIKNTTKLISTSADKTASLWDARSGEILKTWKGHQDAVLCFTNTSDGQYVITGSDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXU0</accession>
    <name>A0AAD5XXU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000380">
        <property type="protein sequence ID" value="KAJ3218430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXU0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="312" mass="35311" checksum="BFA14F4F4DAB8357" modified="2024-05-29" version="1">MPPVSLWQVRLMIVWYKKKRERVGPNRIIIDWQDPDWQATMRVCICAFLSSALYTIGLTIHMNWLACYIYHYPFMLVVGLDVFFYSELQIVRILKIINKPQYLSTVRFMAVFLAVALTLGIGAEQIIYVVDGRCHFAHGYYSSAIYAAVIAVIDGATTLFFAYLLWKSQVSKKEKSSSLNNLILVNFIISLVYIGTSFFCFFGSYATQSEMILVNYDLVYDSFVGLLANALRIGQIFGYQAKKKKKLETSMGMSDTPSETDKGWISGSTNNEKSQGLNSEKSSRIQSTKATSEMFGSECENSSNYDAGMEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY01</accession>
    <name>A0AAD5XY01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MAF1</name>
        <name evidence="7" type="ORF">HK099_004807</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000351">
        <property type="protein sequence ID" value="KAJ3219113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY01"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000994">
        <property type="term" value="F:RNA polymerase III core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.50">
        <property type="entry name" value="Repressor of RNA polymerase III transcription Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015257">
        <property type="entry name" value="Maf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038564">
        <property type="entry name" value="Maf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504:SF0">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09174">
        <property type="entry name" value="Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3219113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="38595" checksum="51FA55ACF9D629E0" modified="2024-05-29" version="1" fragment="single">GVVFGTWQAIKWKQSELNMTYTFVPALIVGVVSYYITAIFLSVYDSAIDTIFMCFLEDDERNDGSLEKPYYYSDNLKKITGHKNAEEANFRFQQMKYLECSQLEALNSALNCIDTGDLRMFGRIECYSCKNTYDDKKLFSYFNKKYEKEESTFEVKSLSSHSPELFNHLSTSDGLNLVNFAIPRKNLFFLLATLNAAFPDYDFSDVKPDAFITIPKLGLVVNNVNTTLFNMGNEKFAKIAGTSIWDSINEIINLDECEIYSFIPSLEIEPDAEEGNVWSFYYFFFNKILKRMIFFTCRAVSFMAQLQDGENPDLINDLIEDDELSLKRQDSQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY19</accession>
    <name>A0AAD5XY19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000074">
        <property type="protein sequence ID" value="KAJ3224987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY19"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035251">
        <property type="term" value="F:UDP-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48047">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48047:SF235">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="49271" checksum="79455597E66189CD" modified="2024-05-29" version="1">MFEVIDKANAKKVLLLVPPTYGHVYPMIELGNYLIQLGLKVTIGVSSCYIPLLKEKAGSLLDQFLLLGFQDTYTVEVGFNDDTINELCDSVENFFYHSENFFDLVIVESFLSATISTTKKFTKILCLLVTTSGQRFIKLKSNQSYPDFIKKVKFHLIDELENKKNLNYVLISSFEGLEKNFFETYKSQLDCYNCPFKFIGPLGAYSRQMQNVKPSNNLQPPYTQLGQYLDSKKDKSVIYISFGSCGYISEKQVREIALALLEFKCCFVWSCKTELLSNLTEEIRISLNNLGLCLEWAPQVTAHSQSLTPKKLFILSHKAIAFYLTHTGWNSTCEALEKGIPMLCWPLEADQHENADLLVNLKVAHLIPGTRDASTMKGPDGEGDGRLVPHEELAAKFKYMFDELEVYSAEARKYIKLSQEAASNGKEFLLSVVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYG4</accession>
    <name>A0AAD5XYG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007477</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000728">
        <property type="protein sequence ID" value="KAJ3213281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYG4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019170">
        <property type="entry name" value="Meckelin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09773">
        <property type="entry name" value="Meckelin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="90" mass="10470" checksum="75C7BE5D58F85B5B" modified="2024-05-29" version="1">MRGKLESFKKKEEPMFVPESSAVEAHLGMNRFLCSFFDKNLKEFQYQMKEKSYFQKYFGVASSDLRDDAFHSTSVGSTLFHGIIKKNKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYH7</accession>
    <name>A0AAD5XYH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000501">
        <property type="protein sequence ID" value="KAJ3216057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYH7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="121" mass="14048" checksum="38B66EE8ED411810" modified="2024-05-29" version="1">MQAMSKLGQKNSHNPLKISSNSIHTYPAIVTSDLPLQTIDDLCIIFEENDVRYIQLTEEHLETEAILISPKVYLDDTLNCWFDTKSFGDYYSQEVLESAMVDIQEENERDSESDWEFNNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ40</accession>
    <name>A0AAD5XZ40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UBC2_1</name>
        <name evidence="9" type="ORF">HK099_006418</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000550">
        <property type="protein sequence ID" value="KAJ3215358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ40"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000004">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="152" mass="17500" checksum="C15D0B6249844C3B" modified="2024-05-29" version="1">MSTPSRRRLMRDFKRITNDPVEGISGCPLPDNVLMWNAVIFGPEDTPFEDGTFRLTLEFDESYPTKAPKVKFVSRMFHPNVYANGDLCLDILQNRWSPTFDVTTILTSIQSLLHDPNPSSPANVEAARLFQENKKEYNKRVKETVEESWDCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ73</accession>
    <name>A0AAD5XZ73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyruvate kinase</fullName>
            <ecNumber evidence="4">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_006244</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000527">
        <property type="protein sequence ID" value="KAJ3215685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ73"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="15">
        <location>
            <begin position="76"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="15">
        <location>
            <begin position="233"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="16">
        <location>
            <begin position="386"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="652"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="672"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3215685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="729" mass="81053" checksum="85A1CA275D7E229F" modified="2024-05-29" version="1">MTQPEFEPVLQKPHESIRKTKIVATLGFKTLNLTKFEKFFSGPASIPKLRELILAGVNCFRLNFSCNDFGPDLPSIPLKKGQIVSIKIAPEDNLNLPGDLNTIMVQIPEIVYQLQVGHRVLLDDGSLRLKVVNKFPDYLECEVMVGGNLKPKKGINTPDIKLNIPALTDKDKMDCAFIYKMRIVYVALSFVQKAQDVQDLLDFFQAEKEKELAKIPDLENTDPNYSDIEENWRPHIISKIETPHAMVEIDAIIEKSDGIMVARGDLGVEVSFERVPVLQKLLIAKANAAEKSVITATQMLESMINSPVPTRAEVSDVANAVLDGTDAVMLSAESAVGSYPIEAVTMMGAICKTAEEKYLSYGHKISNLELSSMQNFKRSVPSTFCHSIADAAISAAKESKAKALIVFTTSSDMAFFVSKQRPICPIIAITPTLSISKRMMLLYGVVPLTTKVLKVNYSMSFSGSTEEPGSLKYKNTPILDSHNTDYILAETEKDIINYEASVSKLFSNSDLHDNFVKFLPNIKFGDTVVFTAGYHAPFPGLSNTLKISAFGDACKSQKAKKNWNFALDRTIKSFVYSKMLTIEAPNQLNLNFSVDDDDEENDNYNKYQFYSENDNGLVSHLNNSPQRKLQILSDQSIDESGISKSNDISQINNSQSVKQSPNSQDSFHSDKSGSTQKKSQQSVSSRSQDLSSNQLPSSDVDIVSKSRVELLAAQQRLIEKMNEFTREFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZF1</accession>
    <name>A0AAD5XZF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS6_2</name>
        <name evidence="6" type="ORF">HK099_004730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000342">
        <property type="protein sequence ID" value="KAJ3219333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZF1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014401">
        <property type="entry name" value="Ribosomal_eS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002129">
        <property type="entry name" value="Ribosom_S6_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="192"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="247" mass="28412" checksum="B9EBA7ED25AAE3C7" modified="2024-05-29" version="1">MHLHGEFNELNISYPATGANKSIDIEDERKLHALYEKRMASEVKGDALGDEFKGYVFKIAGGNDKQGFPMKQGVLVPSRVRLLLSKGSSCYRPRRTGERKRKSVRGCIVNHDLAALSLVITKQGEQDIPGLTDVQLPKRLGPKRATKIRKMFNLTKEDDVRKYVIRREIVREGKKNYSKAPKIQRLVTPVTLQRKRHLAAKKKQAIEKAREQKAEYAKLLSLRIKERKEKVKEQRRLSSVRRSQTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0L4</accession>
    <name>A0AAD5Y0L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000072">
        <property type="protein sequence ID" value="KAJ3225065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0L4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2720:FF:000001">
        <property type="entry name" value="Oxysterol-binding OBPalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="44344" checksum="6E76C9189D2FE081" modified="2024-05-29" version="1">MSQEKEDLSSEVLDESQGSILLGLISQLRKGSDLHKVTLPTFVLEPRSMLERITDFVSHPDLILETAKKEDPVIRFIDVVRYFISIWHVRPKGVKKPYNPVLGELFRCKWEFENNTEGYYVAEQVSHHPPISCYVFASPENNIIITGEVRPTSKFLGNSAATIMGGGSKIQFLNRPGEEYFVSTPNIYARGILFGTMFMELGDIVTIKCPKTNISCEIEFKVKGFFTGSYNAIAGKVKDDASGETLFNLSGKWSEVIYYQKTNWPNKEVLFDVSTSKIHKKIVAPEEEMNEFESRLLWTKVTKAMFAKDLDTATEEKSKIEDQQRRVVKNRTGNGTKWENQFFELNNDEWKFKCPISDDLLLAKEEIKSFIFSKPRLPMYEKFWTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0U5</accession>
    <name>A0AAD5Y0U5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Golgi apparatus membrane protein TVP23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FAM18A</name>
        <name evidence="10" type="ORF">HK099_002304</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Golgi membrane protein involved in vesicular trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TVP23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000175">
        <property type="protein sequence ID" value="KAJ3222450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0U5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008564">
        <property type="entry name" value="TVP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019:SF7">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05832">
        <property type="entry name" value="DUF846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="215" mass="24298" checksum="1F2AD9A3653F0288" modified="2024-05-29" version="1">MNSDREGLITNAAPFGESSTTIPSNTIDQQQRERSILEQSRTLALLIYLFVNWFITANYIALFVTVVLVLLLAFDFWTVKNVTGRLLVGLRWWNEIKDDGTNVWMFESREGRKNNPLDARMFWISMYAYPVIWGFLAFSALISFKFEYLLIHVLAITLNVANVVGYTKCEKDAKKQMNSYITGASNSMFQSAVGNLISNKVSNFFGGGASTTARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0V2</accession>
    <name>A0AAD5Y0V2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HDA1</name>
        <name evidence="11" type="ORF">HK099_002279</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0V2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="10">
        <location>
            <begin position="24"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Histone deacetylase" evidence="10">
        <location>
            <begin position="289"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3222473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="414" mass="46524" checksum="176382140FCEC66D" modified="2024-05-29" version="1">MKLGTGLFYDVRMLHHINLFQEEHPECPERIKLTFNSLKEKDILSRCTRIHLTPTPGLFSERNKTEMELITSAHSEDHYNRIRATTIENFSELKETTHIDHKDDVYFCRETFLSAKISVLGVITLCEAVWNNTVENGIAIVRYLNITSEFVINICLTRPPGHHAEYNEVATRVMQKKYGIKKILIVDWDIHHGNGTQAEFYEDPSVLYISIHRYDNGEFYPHSPNASLRNIGEGAGVGRNINIPWNGNGYGDADYINAFNKIVLPVSAEFDPELIIGKKNKGFIMLTERLLLVSAGFDAAMGDTLGGCNVSPEGFAEMTLMLKQLAGGKIVLALEGGYCIEALIESIAACTLVLLGDTLEKPNVSLGANDEAVDVVEQVIEEISPYWRCMQQLKVYEDMDVVSEVISEEFNENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1E7</accession>
    <name>A0AAD5Y1E7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003868</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1E7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="446" mass="50075" checksum="67DC9121523DC009" modified="2024-05-29" version="1">MQIPITNRPASINVPLQQWLGTEYDLYQWQINALYSLYRGRGLAFALSVNLSCARIATALNDNISPWISTISVPLVGMFLFECLFPNSFDNAGWVGFSIAFLSFLSGIALIYVDNSENRTIYGIVKDNFDKKLNFEKYKFDDQEAAHLLSNEASQADEDRNVAKLLLNKGNSFDEKEKKKRVRIISKPEYFNEDLENSQYCSDGPSSSVSEIVNEMVIYDYDEEDENVDPLHHSIPDIVSAVGSPICGFLVDKVGKRVSMLIISSILVLATHVWPCVPLLVSNHQVATAYGIVTVALNASLFGFPLIVVTVLILSMYLYYLNKMYNGTLEESISEDIVTSLEENSVNDDTTLSRRRSDDWLVTKVVAEGLLVFAPRTVVHHNHSSSELISSPTSPIRRGRSTCLCHSDHIMQENAECNNEISHVLRRNKSRSKTPVRNANLDNETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y266</accession>
    <name>A0AAD5Y266_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000110">
        <property type="protein sequence ID" value="KAJ3223970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y266"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025183">
        <property type="entry name" value="DUF4110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052588">
        <property type="entry name" value="Kelch_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13422">
        <property type="entry name" value="DUF4110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4110" evidence="2">
        <location>
            <begin position="499"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="605" mass="71131" checksum="9AA4812D5BFE2220" modified="2024-05-29" version="1">MGKGRDKKKNKNKDKTNAKSKEKEELKAKKKNQKKNQDNEEISKEEDIDYILNSLRLKQELECKVTKETISELPTRRVNGSLFSNPLNSNELILFGGEYFDGKKIYLYNELFKYNIAKNEWTKITSPNSPGPRSGHQMIAVSSGKAFLFGGEFVSPNETNFFHYKDFWSLNLENFSWEKLEIKRPTPRSGHRLTIWKNFIILFGGFYDVGVKIQYMDDCWIFDTCNLFKLMQYFKAIYLLVTYEWKKLDLKEPKPGPRSGFQFFTHGDSAFLCGGYYKKQIKGEKSEGVVYDDIWVLKMNPDLEQIRWEKKKKPSGLQPSKRSGCTMIYNRGKGYLFGGVEDLIDTEENLESKCLNDMYSYNCDSNRWFPQTLRTLKNNKSKKDDDKTKLAADEIQSDENSIVESEMDSKLSEEYCLLDSNNDFQPVMFPWPRMVEWNNIVFDKIDGSEWFGEDSQSEESDAEDEDEDSEEEGDERDNEAEEKLKQIELKQKEFLKQQEENESVPLPGEKLGDYFNRTIGYWQLRSLEYVESINTNKFRELSSDDVNYDKGLRRNAFVWAKYHWKEWQPKLEKLKCFLEENEVKLDDGKGVSQTETDNKESRNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y272</accession>
    <name>A0AAD5Y272_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MSOX/MTOX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000073">
        <property type="protein sequence ID" value="KAJ3225022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y272"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008115">
        <property type="term" value="F:sarcosine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045170">
        <property type="entry name" value="MTOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10961:SF46">
        <property type="entry name" value="PEROXISOMAL SARCOSINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="476" mass="53768" checksum="D864379C9BBFC7AB" modified="2024-05-29" version="1">MKILIIGSGVFGVSSAIQLRKYGFEVSIIDRSPIPALDAASTDISKVLRTDYGVDKVYTRLCLKAKKKFLEFNKDSKVKLYHESGVAMLAKESNQCDLDSISTIKSLSDDVNGINLLNDSQVRLEFLKSKPGFKKFFDIYKNGYFNNASGWVNAEESINFFIKKAREIGVNFFCGNGYGFRNFVYEDIKTKEKILGVETTDSTYFDCELVLVAAGSWTPSILPELKGCLTSTGHPVLLIKVPPELRDKYSYPNFSVWSADVTKTGFYGFPLNEDNILKIAIHGSGYVTSTDSPLTVLDNKNLQIPIQDLEKIRNFCIKHFPDLFESENDSEVFNTRICWYCDSFDSDFFITSVPSLSKNLVIATGGSGHAFKFLPVLGELVLPVVLKTLNDFQQTNFKTELKIEPKFLFRSPTNHKFSIYNTDEYEKNKNLLGKESMRLVEDIVPLSLEDQIFSTRVEFNNFFKAKDNSAVLNSML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2S8</accession>
    <name>A0AAD5Y2S8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Structure-specific endonuclease subunit SLX4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2S8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033557">
        <property type="term" value="C:Slx1-Slx4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018574">
        <property type="entry name" value="Structure-sp_endonuc_su_Slx4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09494">
        <property type="entry name" value="Slx4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="606"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="612"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="771" mass="88395" checksum="3FB6970D4156FBE8" modified="2024-05-29" version="1">MNMCLDGTLSPLNKNEQVLEHEKILIESDGEDFIQTDNINKGSKKINNNFSQKKLQKKEIKKLEKNDPELQLGLTLSKSLKGIKSRSKKRKIGDPFFDGSNLLCREEVDKILLTKDRIDNILDGVVAGKSPEEDLNENTIFPENETKLDFTLWEKQAGRATDEAFYNVDIMKGISETEEGGITKHISELKAEYSKTVKKEENLLFDKINALKAEFNEKLLQLKENRDLKIKTLISEHNIKMKNSKILINTKPIQADKEEEILNIGGDFKENSIKQNVGTDSKTDGVKIEQLENRNVNSQIKSCQLEIVEETIENIDPLIGEGDINIDDHDCKDDKNSVSEHANIYENFSDYHSDVTYDLTKEELLKDISKKTENNNNALKKKRIISPVKEIKENFTIRKISKNKSSKIIPKEFNLNFDVSPLSLPTISPVNKQSWNSQFNSQMLRKEQLSEYPKFNEKEETFYSLNDASVCNIYTNDNCLDVPDDFNDDYYNFSDYDLLTNASKFENAEGSTVIHIGEDDELDFVNTQKGTEEPEKKEKKTFLHLRESSLLKKKEGVKKVKEKGTVEKDITEVYKVIKKKPGNISEKIMELSADGCLNKKKTVKVAKKPKEKKNDNASNHEELADVRENTREFPSVENPGCPEYHKMSLTELKNIAGRVGIKPGTKIQLIKELKKIWFELNQTNYVSNEEELKIEENLIVLQKKLLNFFKSDLGLYEKILTYQPVDVDLILPKIINSGVKLSKKQLTSFFDSRGVTFICSNNNKDGKKKHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3K0</accession>
    <name>A0AAD5Y3K0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SNF1</name>
        <name evidence="14" type="ORF">HK099_000078</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3K0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12122">
        <property type="entry name" value="AMPKA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000407">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032270">
        <property type="entry name" value="AMPK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013896">
        <property type="entry name" value="SNF1_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16579">
        <property type="entry name" value="AdenylateSensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08587">
        <property type="entry name" value="UBA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3227824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="444" mass="50455" checksum="2DBF34E74BDAF716" modified="2024-05-29" version="1">MVMEYAGNELFNYIVERGRMTEDDARRFFQQIISAIEYCHRHNVVHRDIKPENILLDEFNNVKIADFGLSNLMTDGDFLKTSCGSPNYAAPEVISGKLYAGAEVDVWSCGVILYVMLCGRLPFDDDYIPALFKKINGGIFTLPSYLSHDTKSILSSMLVVDPLKRATIADLRNTSWFNVNLPDYLKPLPEYKEAPTSEADKAVVEELTKKMGYSHDTILFALAEKDNNQIKVAYQLLIDRNKLVEASLSREFKGNVRLTSNVSREATNSTRKMEFAQAQNDIDESSSGKNSNQNSLLAVPAKNTEITILSSSLPKNNLDIPPNQKKSKNKSKWHFGIRSRSPPLDIMLELYRALQNIGMQWKTIDAYHVKCKYKTIKNTEVFFDMQLFRVESNNYLVDFRNTTPPYEQHLKGQKEDTPIELVNLSAFAFFDACSKMITELAISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSW7</accession>
    <name>A0AAD5TSW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bulb-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001830">
        <property type="protein sequence ID" value="KAJ3200815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSW7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="entry name" value="Bulb-type lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01453">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bulb-type lectin" evidence="1">
        <location>
            <begin position="10"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="121" mass="13893" checksum="F8EC0CD494402199" modified="2024-05-29" version="1" fragment="single">EILRRRRTVDSTLKENERLKFGDVKKSQNGKFELKFLEDGNLVLYNNNHQPMWAAHTKNRQNTNYAILKNDGNFCVFSQTNDKLWETGVRGKPSQAPFHLQVLDDCGLAIKGADNSIIWTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTN0</accession>
    <name>A0AAD5TTN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001996</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001624">
        <property type="protein sequence ID" value="KAJ3202090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTN0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="557"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="383"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="516"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="383"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="401"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3202090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="614" mass="69893" checksum="25292A08E412234B" modified="2024-05-29" version="1" fragment="single">MSPITNIQLIQTGPNAVFNDFIIEAGWGKAVSLTGKILLTIRKPLKDAKITAIFIGTSSTKWIGNRPPESEDKKIPLTYSKNFFESFTSIRDPRILKKNKFSTELSPLKNIEDSSLIPLDIPFSIDLPASTDFPQSTKDSRASVLYNLKVVVNWQNNAFKKNFLETSCEVIMLLPDWARKKLISQDLPLSHHLPFTMGKCDVILDIPKRILSPKEYLSADVLIRSIPAGKSLRYVDVSLRSTLELKGPHGIGSIVNFTRPLSEERDIPYSQPDGKRLSITGEWKKNFKLMVDETLAKPTINSLLFSVKTVFRVEIVLDDNPIPNVVFEIPVTILSLQENNSFIFSNTEEEEGSTSATINSKTLSLDSSVASLRNLFTQKIPSRRSTFSMRSRSSSPTKTSGNRYSQNYSNDSLPSSLNEGSLYSPRNSLDYPLSPRDSSPSTPVNLYEIMEEEYFEDNLVEYNRERRPSLAEQKLDELMSEILPYRRKSVDMAYKPSFNYQELNSKFCQQKKKNSLIFLDNQLKELEEFVAENEREINEKLKRFEYHPRQSSSINAESLKKYRVVYPYQPKKNDELELKLGDIVAVKKIYPDGWALGYNLTSMMEGAVPVVNMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUF9</accession>
    <name>A0AAD5TUF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001180">
        <property type="protein sequence ID" value="KAJ3205732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUF9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="131" mass="14579" checksum="E83DF49ABBFC5FFF" modified="2024-05-29" version="1">MAPSTYEPSAQVYARSLAFVSSFALFNGGLYTFLWSWQTIPDLLPPSIYGPLPYTGVLALLSSFIIYALESFPDSFRSIQFWPKIVFYFLLGIIVFFTLTLVIASTCLFVTSIVLTIGAMNSTPPSEKLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUI1</accession>
    <name>A0AAD5TUI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ran-binding protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RANBP9</name>
        <name evidence="3" type="ORF">HK099_001193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001311">
        <property type="protein sequence ID" value="KAJ3204347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUI1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12909">
        <property type="entry name" value="SPRY_RanBP9_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035782">
        <property type="entry name" value="SPRY_RanBP9/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="1">
        <location>
            <begin position="29"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="CTLH" evidence="2">
        <location>
            <begin position="290"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="469" mass="53240" checksum="99AE9CE60B684F0D" modified="2024-05-29" version="1" fragment="single">IPDYLNETPVKLNLLKRNFSNVQENSLLLKNNDKNKEEKIQKNIYQIPTCYNQKDKINTLELSKQNSRVTYKGQGKSDSDAASVRANFPIPNQCGIFYWETEIISKGRDGYIGIGFCTEKVNLQRLPGWDQNSWGYHGDDGHSFQCCGTGKNFGPTFTTGDIIGCGINFYEKCCFFTKNGVFLGIAFKNLDTSLKLFPTVGLRTPGEIVETNFGLKKFSFDINHCFGEEKFKIMQTINQDTKLDFDLNEVICSYLYHNGFVETAHQFFGDTQLEKKRLDLDVNMESDNSNLISRRAIIHYIIGGNMQAAEAEIEKEFPNLLNTNKYLRFQLQSLNFIEMVKISHREPMGPDGTFSKANNVNAFGDIIKFGRHLQENFGGDSIFEEALLEIFSLIAYNDPFTSPHSYLFEEYTREGVADAINRILLTASNNSPTSSVEELFKQLNVVLEEMVNSGIGAASFLNIEKEFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUL3</accession>
    <name>A0AAD5TUL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002027">
        <property type="protein sequence ID" value="KAJ3199830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="225" mass="26664" checksum="4F8AE4B8130BBF00" modified="2024-05-29" version="1">MSASPKEMDSDTINKIIQQSEFNRDIHKYGNLEAMYNYHNNLFSMPFIPSTRYEFDNLYRSYNEEQYLAWESWMLESKLAKLVENQKNESLIASPFYETICNSVFVSDKRTLYFIKWLVGERQCTIFMDSIDKRFSFTMYDCIIFEISYVIIHSVQHFLELNDKLELKKEGEKSLDPNLVEIIYDSNFNIIAYDENTGSTLAEGINNCIAKKKLEKMRIFLDQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUT9</accession>
    <name>A0AAD5TUT9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001890">
        <property type="protein sequence ID" value="KAJ3200510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUT9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="105" mass="11887" checksum="A0FD8102C40A7519" modified="2024-05-29" version="1" fragment="single">IIKENHLKEITLVKFNLNVNINKDLDVSNLVATIGSNQLNVYDNEHCGDHLDIMSNFQLKPEETLKAMCWINIEEDCLMAVSSSNIIRLLSLARSMEVFTLNGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV13</accession>
    <name>A0AAD5TV13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001194">
        <property type="protein sequence ID" value="KAJ3205561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV13"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="78" mass="8897" checksum="E0EAA38507755D7C" modified="2024-05-29" version="1" fragment="single">LNEEAGRLLLEDYDSYASHARMITKIHAMTGVTMEVPHQSEKEVLNPMMLNSNKSNNLNNMNEKLGKDKKVKKGLKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV22</accession>
    <name>A0AAD5TV22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Actin- protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ACTR3</name>
        <name evidence="8" type="ORF">HK099_000690</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001170">
        <property type="protein sequence ID" value="KAJ3205871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV22"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10221">
        <property type="entry name" value="ASKHA_NBD_Arp3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000029">
        <property type="entry name" value="Actin-related protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000006">
        <property type="entry name" value="Actin-related protein 3 (ARP3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3205871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="386" mass="43827" checksum="B9B04DA988F3F77C" modified="2024-05-29" version="1">MGYAGNETPQFIIPTTIATRETSAGSTISKSSGQNFSNLSSKRGIEDLDFFIGDEALLNSKTYQNSWPIKHGQVENWDLMEKYHQACLFQYLRCEPEDHFFLLTEPPLNAPENREFTAEIFFESFGVKGLYIAVQAVLALAASWTHKESQRTLTGTVIDSGDGVTHVIPVAEGYVIGSSIKHIPIAGRDLTYFVQQLLRERENSIPPEDSLEVAKKIKEMYSYVCPDIVKEFKKYESEGDKWFKRHEFIHSVTQKPYTIDVGFERFLGPEIFFNPEIASSEFLTPLPDVVDGVIQSCPIDTRRGLYKNIVLSGGSTMFKDFSRKLQKELKKTVDARVRMSETISQQNMDTMAQIRSKEVEVKVLSHKRQRYAVWYGGSLLADTVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV30</accession>
    <name>A0AAD5TV30_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ACT1</name>
        <name evidence="4" type="ORF">HK099_002703</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001917">
        <property type="protein sequence ID" value="KAJ3200384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV30"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3200384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="373" mass="41387" checksum="9C3DD159E62ACD30" modified="2024-05-29" version="1" fragment="single">MTDDVAAIVIDNGSGMCKAGFGGEDAPRAVYPSIVGRPKYHSMMAGMGQKDSYIGDEAQSKRGMLSLRYPIEHGIVTNWDDMEKIWHHTYYNELRVAPEEHPALLTEAPLNPKSNREKMTQIMFETFNVPAFFVQIQAVLSLYSAGRTTGVVMDSGDGVTHVVPVYEGFALPHAIQRINMAGRDLTSYLGTLLMQRGTTLSTSAEMEIVRDIKEKLCYVSLDYQNELKAALLSSAIEKQYELPDGQVITVGNERFRCPEALFDPSVLGMESCGVAETTYNAIKKCDMDIRKDLYSNVVLSGGTTMYPGLAERMHKELAALAPPSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEMGSSIVHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVP5</accession>
    <name>A0AAD5TVP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">UDP-N-acetylglucosamine transferase subunit ALG13</fullName>
            <ecNumber evidence="4 12">2.4.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Asparagine-linked glycosylation protein 13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ALG13</name>
        <name evidence="14" type="ORF">HK099_008568</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 12">Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UDP-N-acetyl-alpha-D-glucosamine = an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23380"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19510"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57269"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.4.1.141"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Heterodimer with ALG14 to form a functional enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.141" evidence="4 12"/>
    <dbReference type="EMBL" id="JADGJW010000958">
        <property type="protein sequence ID" value="KAJ3209138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVP5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039042">
        <property type="entry name" value="Alg13-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12867">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12867:SF6">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYLDIPHOSPHODOLICHOL N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 28 C-terminal" evidence="13">
        <location>
            <begin position="4"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3209138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="158" mass="17736" checksum="29203CA809C1A275" modified="2024-05-29" version="1">MVRSTRFDKLIELISSESFVELLHELKFTSVTVQHGGSPFTLKTIKNIVLKAFSYSDEIGKYFEKADLIVSHAGSGSILEALELNKPLLVVVNDGLMNNHQSELAEILNRQGVLLKTNIQDFFEKFKLINDEGFKFTAMESSDPDLFVKALKNLVGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWA2</accession>
    <name>A0AAD5TWA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008149</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000867">
        <property type="protein sequence ID" value="KAJ3210908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWA2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF3">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042225887" description="Thioredoxin domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="65"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="165"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="352"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3210908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="540" mass="62164" checksum="F0DB44C3E05559CE" modified="2024-05-29" version="1">MKFLQFFLFLSLSLFVFSQISETRNSEDPKTTNEKKKLTREEMLELASKLDKELFHLSHEDFAKKRLIPKWHKLQKKVFENLSSEYKFKVAKVDCTQDEEFCGKYGVDAYPTIILYIYGFKVVANVKKSQHVKNREAGVFFHPKFLRGRKDLLPEIRRKVTVKKKPSQIKTKLANNTNSYNSPTVPNSSNSFNSPTVVSNPNSLSVLNNSVNMDLLSPITHQVQIRNQNYTPSVNGDFENHHLNTPNAIQNQNLYTQHSNLLMPLPKKNNYNTVISQQNILRNEFQLNNNPMHNDQINDNFFSSNNQTQASSIPYVSSGISFNHQTYGSPPASPMVSSPDVVGYVKNLNMQQQSPANVTTPPLSGSYDSHRRSNPIPIGPISSSYNENKRSAPYNRRRSSYLSTVVGSPIFNLSPDPSSMDLNVSSSYPIQHNDNYREEFLNYFDILNNNQHQNHNNNHLQQQQQSLQQPFDLKNHHQSFSFNEACNDMYNKFNVNHPNQQQQSNYRFSQQVSPPTNNNSEQQILTMFGKESFDSTYNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWI6</accession>
    <name>A0AAD5TWI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor U2AF subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">U2 snRNP auxiliary factor large subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007363</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for the splicing of pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the splicing factor SR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000704">
        <property type="protein sequence ID" value="KAJ3213484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWI6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12230">
        <property type="entry name" value="RRM1_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12231">
        <property type="entry name" value="RRM2_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000097">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000676">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006529">
        <property type="entry name" value="U2AF_lg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01642">
        <property type="entry name" value="U2AF_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="171"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="279"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="400"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3213484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="499" mass="56598" checksum="20EB6A10A8CE94A2" modified="2024-05-29" version="1">MEETLKRDIEEGSNRREERYEKSSSKNEERNDRHRRSDKDTHSRRSSGRHREDERPRHDYDDRDKRDYEDRERRERRRERDKERVKERSISPINLRKPKLKNWDLPPPGYDGMNVAQVKATGHFPLPGQPSRTGASAVVPLPFIHHKLQDGTASAATIPIALNPTIAKQSRRLYVGGIPDNANEMHIMEFFNDAMINLNFAKDGGKSVVGVQINQEKSYAFVEFRSNEEATSAMAFDGITYMDKTVKVRRPKDYIPPAEPEAPVLLPGVISTNVLDSPHKIFIGGLPATLNEEQVVELLKAFGELKAFNMVKDIQTGISKGFAFCEYIDSSITDIVCQGLNGMELGDKRLMVQRASIGQKIDSLLIEAGNRANDPHVMSLNDQMFSFTKNVDGTQTQPSTVILLMNMVFNEDIMNEEEYEDIITDIKQECIKFGEVTNVFIPKPKEEDDALAAAKVYVKFSNIEESGAALKMLSGREFGGRTVITSYYSEEAFFKGEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWL4</accession>
    <name>A0AAD5TWL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Heme haloperoxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_007933</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000817">
        <property type="protein sequence ID" value="KAJ3211709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF9">
        <property type="entry name" value="PEROXIDASE STCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="8">
        <location>
            <begin position="8"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3211709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="190" mass="20993" checksum="542CF8DA941D074F" modified="2024-05-29" version="1">MLFTQAVTIPEWHPRFPNDLRAPCPLLNTLANHAILPHSGRDISQADLVSALKIIGISETIAEKISQEAVHKFGIADKSGVLRIHLDSLSKHNVIEHDSSLSRPDAHFGDQSTFTALLNGAAGEACTLFLLLNRDGKLYKEDLDLFFKKEKFPDVLNEVSSWSLASSMLQFNAQKIFYGYGGNDVTNSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWV9</accession>
    <name>A0AAD5TWV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000780">
        <property type="protein sequence ID" value="KAJ3212405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWV9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="467" mass="54062" checksum="393C482C81FE3B5F" modified="2024-05-29" version="1">MTDVKCLWHNCSKCFQTELDCFNHLQQFHSKPGKVLCHWNSSFPYRLKLCNTILNHKLSFQSHIITHFSKDLKPFKCLNCLFVHRSRQELRKHEAIVHNIQHNAGRKKSKQFSNQETSETDIVTAKSSSENSLVCYFKHGENFVNVSTINNENAESVNVNVFQYFRSPLICGPSIAPCNYGTNIFPLIEAFKFINTNFKLNLSLNQEWNSKFSFIMKNGGYMLPIMLTEFHNFIVSSSKLDVDKFIEVMTLCFEMKLSQVANILYLSLFVTIKNFKDAVINKVKQNQKKVTPLTPAYNNTYKDLLFLILNHLIFHMKIIVNSDDVKIVELKNNSKFFQVKNNCSKSQLGLLLTINTYGNEIALELRKRSNSKFFINKNNYKTSNFVLRETLQQLFDNLVWGEEGDIIRNQCCLGLICKPKSLRERSFVSVNSININSDQILIWFKIGIDLSWVNSPPPTPDEPFVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWX5</accession>
    <name>A0AAD5TWX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001346">
        <property type="protein sequence ID" value="KAJ3204060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWX5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="187" mass="21751" checksum="E4DE94ED022588F3" modified="2024-05-29" version="1">MEFEAFVMKVGFDCIWEFEEIGEDGSIGGGNEVADESIEVLFVQEIQDLNAAVVAVERNAVEEKKNFVIEEKRNFVIDEKRNFVIDEKRNFVIDEKRNFVIDGEEVLDFIKELTPKMRDHHLIEAHIRDFSLIKLFFLVDRKKMKDEDNIFWRQVLSTIRKSGSQASVSTSDQWASSKKRGGWSLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX17</accession>
    <name>A0AAD5TX17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DPH5</name>
        <name evidence="11" type="ORF">HK099_006930</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000631">
        <property type="protein sequence ID" value="KAJ3214328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX17"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141133">
        <property type="term" value="F:diphthine methyl ester synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000004">
        <property type="entry name" value="Diphthine synthase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000004">
        <property type="entry name" value="Putative diphthine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01084">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036432-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3214328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="281" mass="31863" checksum="23EFEF5E12CC89BF" modified="2024-05-29" version="1">MLYVIGLGLSDEQDITVKGLNAVKSCERIYLEAYTSILMVQKEKLEEFYGKKIILADREMVEQKSDEILKDADKINVAFLVVGDPFGATTHTDLILRAKQLNIKVKPIHNASIMNAIGSSGLQLYNFGQTISIVFFHENWRPYSFYDKLKINVNLELHTLLLLDIKVKEQSWENMARGKLIYEPPRYMTVNQALDQLLEVENAKKDNVINSNSICCGIARVGSDDEKIVSGTIEELLEIDFGAPLHSLILCGKMHFLEADYLKTFAVNVETFNKYASIFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXD5</accession>
    <name>A0AAD5TXD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000652">
        <property type="protein sequence ID" value="KAJ3214074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXD5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="16809" checksum="B906A5C214E3AF74" modified="2024-05-29" version="1">MVSGGSNELHLRIDLATAISNSSTVFVRDLNEDSRKNLNLNSFNSCKLSKSNATLLNLEYLFKLMKNNAAIFILLEQGYAQNEVEEITTNLKLAGFVNPALNNNEHYIEAKKPVYEVGKVTRLVRKKKVTPETGDSRITFISYIVLAARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXM1</accession>
    <name>A0AAD5TXM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-activated protein kinase glycogen-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007058</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000654">
        <property type="protein sequence ID" value="KAJ3214050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-activated protein kinase glycogen-binding" evidence="3">
        <location>
            <begin position="947"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="762"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1066"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1215"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1778"/>
            <end position="1805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2339"/>
            <end position="2361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2497"/>
            <end position="2521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2555"/>
            <end position="2575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2590"/>
            <end position="2609"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1073"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2348"/>
            <end position="2361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2510"/>
            <end position="2521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2555"/>
            <end position="2574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2595"/>
            <end position="2609"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="3114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3214050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="3114" mass="345842" checksum="6AA2E55C9AA8447F" modified="2024-05-29" version="1" fragment="single">MEKDRARKQKLLDMESSNEKLKERVEKLTNNKLNWNGSTKSKWFSTKSTENLREQRLVQSKTMELQKSNLNTSLCQNADLNSSTVSNLGENSTNSTSPIEIISSPNDKNFKPVSPKRSFSVNVKRDLEESKKWPKVRDIVGRFDQAAAELEATGQSSSPPTLDSTLRSPVRSFSSPLNTNSTALTSTMKNPPQILISPSITSTKSESTLKSPTQTLTQDTNPTSILPLSVTSTEISNSSNYDSKSLMNKNNLHSTSFSNLLMKKSSLILKSSPPNFSFSNPMFSEKVADYDEKLFSEEDVSSIDGIEDEVSEDPDILSTSVSNSIFTSTSEDDAFEIIDVNNNVNNMDNTFTFEKENINFPEIRQKSSVSSLTELILNQEVESDVKSTTSLTSYNVNKIPIDDLSSASTNRNAPAITTALGSSEPILDAIADSTILKEKNAKLNIKTEINIERNEETSPEFVLPKRQSSLPVFNQLKSKEPVFSTHKNEPSKNSQISTNIATENKVKKSVSFSAKDEFFVINEDENTKDTVIGNENSFFTSPNNQLHSVTNNVKNIVDKKEMTDKEDLSVAQRVDIPVCSSPDSERYVEKNTASQFDEKMKNPPSININQNVTGGKDDYRRSPSPSSSFIEEIIISKVVSPDVAGVTVNLKNTASKDDVKADHVLKRPRSIIIIEERINSKIDNVTEAAEVKPVTADVDNITPASEKFMELNPKTTEMESEDNATKSIPDSENNQLNLVTESDPCDDFTTMIDSVNAAKSIQHSMETQNSSTSPKTVPLQNAESLESQEQNAAEVVSESRRISVSDAVNEINDGLELVSEVQVKRVAEVSEEPLKIVTDLVSETSVKSFPDVVSEETVKSVASVVSEEPLKSVLDVVSEGLVKSVAEDSEELLKSVAEVVSEEPVKVVADLVAEELDMNIITNSSKVKPEFVRFNVSFSPAHHNPKTTVVFTGTFDSWSQSLKLTRVHNTWVGSILLNIYKDYQYKFVVDGLWMVDTSCEMKEDDFGNVNNYISSNALKELKRIKDLTKDALQKVSQPETEVVGEEASEKDDNQHFTTEAVEVEVTKNEESSSKPTIMSQKVSQPETEVVGEEACEKDDNQHFTTEAVVVEVTKNEESSSKPITIVGSLFPTVEKNIGVLYDAIQLTPEIQTKKPPIHKPKHTVSSDALTKLKSKTLNRRSWHNEFESSGNDLAEPVIKKIGDFDEFGIQFVENNGYDSDSSDEGTTIPLPRDVKNNDVVPVEEINLSDIIGEEVRYQVASDNTSVRKLSNAGLGKKISLTDLQSTANETSQNIAKKGLLDEAGRVIYPDGYDPSRRIILKKSFSDQNGRITKRKSADLKNLKKRVSWLDQLETKESSTLRRKSSQVLKKKPSWVLGEGEDALIVTEELVETDPSDEESPLFETENWKTWKPNLPLPRSSNEAEKLMVESSEEIQFTDTKTVGCNRNSNNKAEHKIPDLITFDDTVISHIETENDIKENIQQLKVLCEKNHNFSHEDAILPQITEFSLFDELSSVMTNKKSIETFLNHSSPNNEPFETGDIKAAEKADTTEVETDLLKELAGYTLRNPEIKNDSSSAESSDAYIDALLKQSVEEFLPETEDSLVRKELAEYKFPVEQEPFKFQSESDKFIENLIAETVEELVPKSPITEAKMYNSCDSEVNIPNVQDDASSIMNLPAAAKSSAKEESKLEVFKDMSLFKFPQEDSTSAEFLTGFKFPSFTVDKFDTNDLYEKEKALEKTDSSKFSQSTSKVSNTETFNNDKYIDNLLNDSLLEFSEKLESTKTTEESSNSVTAQPVTPSTVPDGLESEKLADGLSFTAEVVNYHFFVKEVVSESLSVALNAIEVTGDAVQMKNDTIEGAKLIIEKEALMENGFSNNSHLNNTLSHSRSTSLPVSIENSVKITEPTQKVQPKKSFLSNLFSFMKEKPTEKVAIKPTEEKVAIEPMEEKADSSPSNLVKSSKVHLESEAQDLPKVKSLEKFNLLPLEVKQEYEEPTIKSHTFENDDKECEDAAIKPLSIIQDMEGTDTNSEIAGKDEEESLVEPSKIYQYVNEGADSKNEINGVDHKVDKLEEDSINRKEYTSECKEDIVNLNKNATECEELIVEVNEIAPECKEDIVEVDEVAPECKEGIVEVGEIALECKEDIVQVDETVSECKEDVLEQEKKISECKEDCHVVNDVVGISDKSENSNSIYIVKTLTDVKTSNVAASDFLQLNTFLKSLVGPTLLTDVENVTIEESILPDCMSTEVQTIEESSNTLELTTQVALLSSDESNPDSILATSQLKTLIGAEDVKIRDEESLSSSNAAALKTREIESNSERGNVDNGRISERLLKLFHQTNSDMESPSRDFSVNLESPNNSNVSSVSGIVEEEQNLVVTAEHNNENLSTAVTDYVDSVESSVKDVSVFKEAAMKLPNKATDVIDKVPDDSAIFANVIEEIEGVSILNEEIASDVVSIENAIEHFSALPVEKDSINSQNTESAKNLSDIADLNVAENAQNALPEVTEDVSNSSKKPLETTKKEKKETKVGFLSERLSRLFNLTKADDPVELTPLNYTDEKAKLSNSKESKLSKNSKEQPLHTPLSLEIPIANKPNASPIKAEESPIRPNVKSDDNRDAIDVDKNHMQTVEDVTTLDSKSLMVSEKCSTKDDAVAEKTVDVNPLAFDDKDEDAAVEQAYEMQVNTPIISKDDDAAVEQAYEMQVNTPIISKDDTSLLAFDNTAEWAKEPFTIEKCVRTINEVSGEDESQHMDDSGRQAEANDLNDIQPTSLQEEVLFTALDTSAADEMPLALEVQIFPDSNTNTPEIMTNKSLYVAEASFSKDNLIASVANNDFIVTSEMNYLADIFSYINDKSDTKPVPKQEVLSQLPTEPPQHTNSLELGEKPAIIEKDTLDEEQIMILPASDTDEKKSTVSELEAEFIKGILVEIIDKMNYLGREEKGEDQKSNTTDEDVHNLMRDIVFEVVDNVEIVSGKGKDFDAKITRFDSGLLTEAEVDCYDVQLSRDISTDREVDQSHKEVEKELCEADIERDAAFVLAEENPDALSRNSQFNIEKNEVDTVVNAIVDTILKEALQEIKEGNQPKVTRSVEIKQTFQEISMSEVKKIMSDLSALSLPELITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYI4</accession>
    <name>A0AAD5TYI4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">XRRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006217</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000522">
        <property type="protein sequence ID" value="KAJ3215753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYI4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014886">
        <property type="entry name" value="La_xRRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08777">
        <property type="entry name" value="RRM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51939">
        <property type="entry name" value="XRRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="XRRM" evidence="4">
        <location>
            <begin position="61"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="174"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="219" mass="26411" checksum="9C561898FE247813" modified="2024-05-29" version="1">MKANFLYNFELDTETTWNNANIMKMEEWLKRMKEYEVLLHERKLLLEEAINPKLKKRKYPKMERGCIVKFFGGIHPKTNRLTLKKLFSVAGEVCFVDYKSGENEGLLRYKSSHAAKLSLSYFENKKIKQISDADTCLKLNLDYEPYTTKCSFEKEDYIKLQLVEDEEEKDYWKMIKQERKKKKEEERLENDRMRIEEGKEEQLRKKSHVVFADDFEDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYK5</accession>
    <name>A0AAD5TYK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Mitochondrial chaperone BCS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_008572</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000959">
        <property type="protein sequence ID" value="KAJ3209116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYK5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19510">
        <property type="entry name" value="RecA-like_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000768">
        <property type="entry name" value="Probable mitochondrial chaperone bcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="BCS1 N-terminal" evidence="15">
        <location>
            <begin position="21"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="239"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3209116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="440" mass="50063" checksum="41C079EED658566C" modified="2024-05-29" version="1">MEFAKKLIESNPLFNAGIGLGVLGFGAAIFRKGMSQTYKILQKKYIISMEIPSKDPSFPWVLDFLSKNELKNKMLKKNKSNFLFKLKPLPPNKLSVNTDFIKRENGSTSHSFNLNPGIGSYFSQYNGKYFFVERTREAKMIDLKNGSPWETLTLTTLSMDKDIFLNILEDAKKEASLNETGKLVLYTSWGVDWKQFGLPKRKRNFDSVVLDNNIAENLLMDVKNFLKNGSWYFKRGIPYRRGYLLHGPPGSGKTSFIQALAGELDYNICLLNLSERGMTDDKLAHLLNQVPPRSFVLLEDIDAAFPARSEATENTTPKSMHPPLLTLSGLLNALDGVQSSEERIIFMTTNHLSKLDAALIRPGRVDVKQLIDNVTDYQIKKLFLKFFENEEEKSKIFLSKIKEIMLKCNKTLSAAQLQGHFVLFKDNVDEVIENVDKLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYY0</accession>
    <name>A0AAD5TYY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Maleylacetoacetate isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008259</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. Zeta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000893">
        <property type="protein sequence ID" value="KAJ3210393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYY0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016034">
        <property type="term" value="F:maleylacetoacetate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03191">
        <property type="entry name" value="GST_C_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03042">
        <property type="entry name" value="GST_N_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000010">
        <property type="entry name" value="Maleylacetoacetate isomerase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005955">
        <property type="entry name" value="GST_Zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034330">
        <property type="entry name" value="GST_Zeta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034333">
        <property type="entry name" value="GST_Zeta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01262">
        <property type="entry name" value="maiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF4">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="91"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3210393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="24605" checksum="CB5586A8316E451A" modified="2024-05-29" version="1">MDNELQLYTYFRSSASWRVRICLNLKKLKYKSNYVNLLKQEQKSEEYKKINPNQVVPTLKLPDGQILSQSIAILEYLEEKFKLEYQLLPDDAIKKAQIRSVVQLIASDIHPIQNLRVLKEVGEDKKAEWAKKWITDGFKTLEILLKETAGKYCFGDQISFADIVLVPQVYNAIRWKVDMSEFPIIVRVEKNLSLLDEFVNAHPDNQGDCPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ73</accession>
    <name>A0AAD5TZ73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tethering factor for nuclear proteasome STS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">STS1</name>
        <name evidence="5" type="ORF">HK099_007241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Binds the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the cut8/STS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000689">
        <property type="protein sequence ID" value="KAJ3213663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ73"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071630">
        <property type="term" value="P:nuclear protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031144">
        <property type="term" value="P:proteasome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1590">
        <property type="entry name" value="Tethering factor for nuclear proteasome Cut8/Sts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013868">
        <property type="entry name" value="Cut8/Sts1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038422">
        <property type="entry name" value="Cut8/Sts1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032:SF1">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08559">
        <property type="entry name" value="Cut8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3213663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="303" mass="34884" checksum="764B2DCD966E6B6C" modified="2024-05-29" version="1">MNKRRLEEENDEDNTYQQRSNKVAAKRYRRDGHNASQEHSQQQSDSGHSISLSMFHLEKILPTLEKDQLLSIVKTLIQNFPQLNTQLQTLIPKPSLSNVTSLLQNLEKKLQNSFPYSKNGTDRSDYSFNRTRPILTEITETIVNYLPFFTVSSSYSPEKDHEFPNNSVEYLHLATNAIHRLPVWSNEKNNVEIKHVMYMMLAKSWRQVISEIGRRVVEEGKVFPSRGVNEWARYIHFHNNEVNGHFGFNAVLSEFNQKLGWILGSSSFHQQSAPWQMQAGGITTGLQASQTPSRLTAPFTFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZC7</accession>
    <name>A0AAD5TZC7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000641">
        <property type="protein sequence ID" value="KAJ3214200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZC7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF16">
        <property type="entry name" value="MULTIPLE EGF-LIKE-DOMAINS 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35202" checksum="6E16AD69A0F0CE4E" modified="2024-05-29" version="1" fragment="single">MQLELLPCSTKLACEVFNKAVHFQDPSYISGGCNTLVEQTVGSVLDTVKTRVKIGVLPVNVAQGYHRGIQATSNGTWREFDVFGIVNALKGHTFTKIINNKMLIYGGVTSSGIISNFLYELNYDNTTLTAQFGVGSVQPPPLMSHSAVFRKSTNELYILFGTTDGVVFNNLIYTYNIQLNIWSVIRPTGVIPENRTLQAVDIVDDNIYVFGGLYKDSVLKDFWIYSCREQTWTQQFHPLSPLSAFGSSLVAVSQNKTLILFGGTNGESKMNLQLWMYSINSSNWMMLNPFGIPPKGFSQGSGVLLDSRRILYTGGVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZJ1</accession>
    <name>A0AAD5TZJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000372">
        <property type="protein sequence ID" value="KAJ3218616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZJ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="14845" checksum="CFF9D954F3579A0F" modified="2024-05-29" version="1">MAEKDNNAQVDTGAAALCFPSVLIGFVKGKLDGSGFSVPACLCGGVAAYRLRRDTQKMFNIKESEDASMCAVGLCGICALYQDVHELQKQGKLSVGGNVVSVQPTQTPAMKEKEAEAVGPAANNPAPPYDKPAEAVVEEAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZL4</accession>
    <name>A0AAD5TZL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005285</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000401">
        <property type="protein sequence ID" value="KAJ3217975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="154"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="369"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="580"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="590"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="619"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="638"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="671"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="683"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3217975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="760" mass="86585" checksum="78907B3CEFB48BE3" modified="2024-05-29" version="1">MPKKNSYIKINPLACRIYLKFNALDIKAEVRFYHWENYMMSLKLKKLPISFIQKPSVNSLSSRALSSFTKQHSVESFPFKYVNKNLTLVTKNNLIYHFSRLSTFAEATLEKSNAEISKSIPDTFSSLNLMEPIQHSIKKVFKYEKMTGCQGPVLSRLPTSKDMLVKAKTGTGKTIAFLIAALEKIKSKDENAWNEILAGKQQTSIIIISPTRELAFQTLTETQKMCKFLPLKSVLICGGEDRRQQLLKLMRERCDIIVATPGRLLDFLDNSRNISEVFSKTKVLVLDEADTLLEMGFREDIEKIVNYLPKERETLMFSATISKETKLIAAQALRKDFLHIDCVPANDVESHFAIRQSYITSTFSQQLPLILDILQRHKESTPNGKIIVFFPTASMVAFFSQVFLRISELNIIEIHSKLSQGKRVRASNFFRRSTNGILFTTDVSARGVDYPDVTLVLQVGIPSTRDLYIHRIGRTGRAGKDGEAILILSPFEKEFLREIRNLNIKEDVRYNSIMASAKKENVDKIKKILQNAPEEEALDCFFTWVGHMRGVFGKYRLRNDNLDIAASEFGKQMLAIESPPRIRVQESKRSNYSGGSQRRSNFERNDMQGVGRGLSGYQNRYNSYNNDSNDFNAGNGKKRYDYKSGRNGGKVDERSSYDRGNRYDSRGDFNGSKNTSRGSRNSSFERRGDRDGARGSRNNNISSDFYSRGNKESGYVKKGQFRTYSNLARLTINDEGSLECFRTISATEAKLVCRNESEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZN3</accession>
    <name>A0AAD5TZN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000396">
        <property type="protein sequence ID" value="KAJ3218109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZN3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="213" mass="25112" checksum="0D4192C7F3D1A40C" modified="2024-05-29" version="1">MPLEEEEKDYVDYYGFILDLSSEVWLQLTFPFISVYTFVVILVFDIVVIIIEGLWRLSSYQTWVITQLSPQQSSSIYELLKILVLKTNANRKRPKSHKQMEKNLGLKEREAPKIKITTVANEIINIDYLSQEIEWIYKAQKSYFIKIWAYFNGQLIFLNLLILQNLFKNGEFLPWIYKYESNDDSITFKDNILLNIGNFNSTKLHGKEVGFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZN8</accession>
    <name>A0AAD5TZN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclic nucleotide-binding domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CNBD2_1</name>
        <name evidence="3" type="ORF">HK099_005115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000387">
        <property type="protein sequence ID" value="KAJ3218298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZN8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011:SF28">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="262"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="390"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="539"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="806" mass="92909" checksum="E8F062F65647F3A9" modified="2024-05-29" version="1" fragment="single">MIDAVPAPKESLKHSKKSSNILPDIKVEMEEEHQNYIRKETNAKTSTFPKLKKNCHFNGNIFSRIAENTPKLAKANLGIQKGYTWLPKTPCSGNHEKSYSYVHKEIKELVANASGFNSNPFYDTVKVLEKTYESSINTLLEISRPKPSAEKITEMLSKSELTTERRERAKQNWKIGIISVIKFMRATKVFHYPEKYNIKNKKIISSTNFSETSMKYLLKCCQTRSDILFNTKVQMFLRKNPEDRTLREMVELERLLTTRLSGFSKFLPTQRLQLCYQLMYISVGAGRSIIKEGHEPKNGIYIILSGQVEITQELNEHTLLRLNVLNKGETFGEIALESFLSKMRTATVSTVTQTELLHVSKEEFRAILVGEDNELSTNFRSELVRNACLFKSKVVETVLQQLISKSDVKVFEQGAVILKQGADNDKLHFIIGGSVSVRKSISLRNVFHTKKRDKYRYENKTVCLEIGKLIAGQSFPEIIIPEWLISDELNLNLDSNLFFEIHHRLQVNGFSYPSYSTVTAESAVRLIQISRVDLFKYYSKENKMIYLLGLQRLRWLGSSLMFIYLSATCQSKKVYLRPYLDAFLYNCSKKFEIAVWTTTNKRNTVTLTNLLVLDIFKPLFVWSEDECDTVGFGKTKETFKDLQRVFEKYPQFNKNNTIVLDDSVYKASLNEDFNSLHLPSFTVCDPCFNPLDDAALLSVLKYFNVMFFKKTKDVTEFISSNRFVEIQSEADESAGYKAPSHALVKHNEPTFVILPMWKLTSNEITLFVGKTDRLRPEYSPELILKYSDDNIDSKVIYIWNDVNFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZQ1</accession>
    <name>A0AAD5TZQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000627">
        <property type="protein sequence ID" value="KAJ3214371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZQ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="113" mass="12824" checksum="8FBD5CA7ACCBCD83" modified="2024-05-29" version="1" fragment="single">TCLKKLRNRQELRRHSKTHCSSSKIVISDSIPNSPPAFLIPPSSGSILLPQVMPTSSKSISSDAENYYIIPPNNIFDEELLPYQKRLEKLAKSINSSHDNVFFTGTTIKFFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZY4</accession>
    <name>A0AAD5TZY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000458">
        <property type="protein sequence ID" value="KAJ3216837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="253" mass="28807" checksum="8ADAB05B0C7A31B2" modified="2024-05-29" version="1">MQFLDLPPPLEDCTELLKKRKKAKSKNQQKFEKIQENPKFNASVDSSLLDIKEDSNILNFSNKPLEKKPAVSQSNNSGQFGGLKKGFFDSKPKEKVKNKITEKNLENVSFNPNKGSSLVIEEVQENLKSENSPSNITSQLLNQINLSPSLMKAFEDPEFALAAEEISKNPTRETMEKFKKLRPELFKAFLEFLNLMGQEVEKKEKKEEKVKVVDKEVENLLKADGIKELLLDFEVQEIVESLRQGKADVNGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1J3</accession>
    <name>A0AAD5U1J3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005483</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000429">
        <property type="protein sequence ID" value="KAJ3217389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1J3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22753:SF14">
        <property type="entry name" value="MONOACYLGLYCEROL_DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22753">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="3">
        <location>
            <begin position="103"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="507" mass="57716" checksum="41366DD04199CB49" modified="2024-05-29" version="1">MATSKPLTSKPKPAKKTHLSNWIVYYILYIATAWTWRYLEELNYTLILFALLLILSPNRPLQKAVKAFMDYPYIALTERKAPPRGLVNFCQNIFKLFFPIVGRGYENIPKHGKVIFIGNHQLLGLDLAALTPEIYLQTGLFVRALADSSHQYLPIFKHVTEYFGACEASRANCQALMDDSQPILIFPGAANEVFKDERHMKYELQWRKRVGFAKMAIENGYTIVPFSSVGLEDLVTVKFSISSAWFWTLIGDKKRAAKNSYAHPESTRFPIPLPSFRYSKLYLNFGKPIDAKDYFSTEESIWDLREQVRIQVENLVQESLQFREKESNFKPSPKTVKPSISNTKESFLAIPSPADSSVGSIATNMNDTLVNDETGNKSISDEKTLDDSANKSILVQLETAIDSTLAKDTTSEIIQSEANLYIANKEFFISDKEKVQKRQLSESNTYLKVRDEKNEEKMSLTTSDYSFSEEELSASTVSQNFSTSPEKKKKKKSLFGIKIGKKKEIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1P9</accession>
    <name>A0AAD5U1P9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial aspartate-glutamate transporter AGC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Aspartate-glutamate carrier 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">AGC1_2</name>
        <name evidence="17" type="ORF">HK099_003698</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Calcium-dependent mitochondrial aspartate and glutamate carrier. Transport of glutamate in mitochondria is required for mitochondrial transamination reactions and ornithine synthesis. Plays also a role in malate-aspartate NADH shuttle, which is critical for growth on acetate and fatty acids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer (via N-terminus).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000245">
        <property type="protein sequence ID" value="KAJ3221193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1P9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015183">
        <property type="term" value="F:L-aspartate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043490">
        <property type="term" value="P:malate-aspartate shuttle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000004">
        <property type="entry name" value="Calcium-binding mitochondrial carrier protein Aralar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="89"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="342"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="441"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="539"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00059916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00082232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3221193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="685" mass="77178" checksum="45D642F19CF69FC1" modified="2024-05-29" version="1">MNLLRLDTPKDITQISTDIFNLYASEEVENKKYLNRNDFINAIKPIDLELNLNFDQNLYSILFKLADKNKSGLIDLDQFVDFEKNIFLKPDNESKILFKLLDEKNKGHINVKDLKNSLQFYQHKEASKIDFTHGPLASYLRDEKKNLSFNEFTEFLTTFRRERFYQEFNSLDYYKTSVISLSEFKGLIKRLSGHKLSDQLENTFDSTFPLGKISFAAAQGIFKILENLDALRFSLEINANPIEKNKIITSDFFKYCLKNKVFTTLELDLIFKLVGETNLIDEIESDEEEFMKNNVKNFIDLSKFEKIFLPSYGKNLKNVEQRLAVKKMTETKYEPTGLMQALFSTYNFVLGSIAGALGASAVYPIDLVKTRMQNQRSSKFIGQILYKNSLDCFRKVFKNEGIRGFYSGLIPQLVGVAPEKAIKLTMNDLVRSKFKTKDGSIPVFAEILAGAAAGGSQVVFTNPLEIVKIRLQVQGEAAKATGAATQSAMQIVRGLGLFGLYKGVGACLLRDVPFSAIYFPTYAHLKSSLFNEGKDGKKLAGWELLVAGAGAGVPAAYLVTPADVIKTRLQVAARSGETTYNGLVDCFTKIMKEEGPRAFFKGGVARIFRSSPQFGVTLFCYEKLHGIIPFTLIDPKFVDHSLATTSTHKGVVEKTVSTSFEKELDSYKRNSLRTTLDILPRFGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U213</accession>
    <name>A0AAD5U213_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD repeat-containing protein 92</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002993</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000203">
        <property type="protein sequence ID" value="KAJ3221887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U213"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="100"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="37821" checksum="EF7488FA6A7E4977" modified="2024-05-29" version="1">MNGIDKPQIITHITKSLSYTPYCVKWIPCSAKFVVLGALQVYELTEGDAKLIIDVEKPSSFKCGTFSHSAISNRTLATGDFDGRLQVYDIENPDISVYSVKAHEKIVNCIDGAGSNFGAPELVTGSSDGIVKIWDLRQRDKPVAKIVPESGEVRDTWSVAFGNSYNDEERVVAAGYENGDIKMFDLKNMKLIFETNAKNGVVALEFDRKDIKMNKLVATCLESNFNVYDLRTYHPKKKFPAVNQKAKDNTTIWTVRHLPQNRDIFITSGGGPGGGNYPPQRTVKSEDDNLEGVPGTLQAIQTVNAAEQPVSSFDWSPDKQGLCVFSAFDQQVRVGIVTKLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2U1</accession>
    <name>A0AAD5U2U1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Vacuolar protein-sorting-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ESCRT-II complex subunit VPS36</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS36</name>
        <name evidence="7" type="ORF">HK099_002283</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the VPS36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2U1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000416">
        <property type="entry name" value="Vacuolar protein-sorting-associated protein 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037855">
        <property type="entry name" value="Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128:SF12">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="350" mass="39020" checksum="5C3A35055CD56DF5" modified="2024-05-29" version="1">MYLHLIFVNSITYVSDASSTVTYLKVTCNICSTTNFSLQNCSNCGVKPTSIACPNCTYRNHFPLTVQQCEICTGNLYHTSSLSLPHPQYLQIQNLLQSKLENSLKSLENFKSPTPAGLTSIFNSIQLENDQTETYLNNAFTDLDTLIKNADEMVKLAEVISSKLANTSNQYNDDDVTKFKSYLVNLGISQPVTKESAGDSFSAQLANELSEFLSKLSKGKGNSKFNGMISLTDIYCLINRARGVALISPQDLYKSCLVLEKSGIYKLRTFESGLIVIHDKNFDEDQICLRIQSLVKNRKKLTPSIFAIEYNVSVLVAKEMLIIAESVGIIARDDSIEGLAYYENLFLTEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2V2</accession>
    <name>A0AAD5U2V2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BD-FAE-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000173">
        <property type="protein sequence ID" value="KAJ3222501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2V2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="2">
        <location>
            <begin position="57"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="38452" checksum="6A715EF78F49E047" modified="2024-05-29" version="1">MKKLMESRKLKDKVLIENIVYKKNKKNEDLLLDVHVAEKKFNVLESLDIQDSFVNIKPVIIFVYGGAWSTGNKRMYIPLAQTLRKKGYNVVVPNYTLFPKGKVEDMVHDIGDCIRWVYENIHKYEGDNKHIYLMGHSAGAHLCSLTVISNALTILQKMEDKADNMGHSRRKFIYSSPQLVLPQYWNQDFLEVLPKNGDRADSQECLMHIDSYPKFEINKQKLAAVSELEIKKVIKKRKENLKIFLPKNWWLVHGKKDLTVPSVASLNFQATLIKLGLDNVHCTEYENVDHSRPVLELFLNESEYTVKFLNDFETFEKTCLNSGLENARTNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2V4</accession>
    <name>A0AAD5U2V4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000254">
        <property type="protein sequence ID" value="KAJ3221062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2V4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006986">
        <property type="term" value="P:response to unfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044280">
        <property type="entry name" value="Hac1/HY5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46714">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46714:SF6">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0834">Unfolded protein response</keyword>
    <feature type="domain" description="BZIP" evidence="10">
        <location>
            <begin position="183"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="627" mass="71100" checksum="24809156E9F78CB6" modified="2024-05-29" version="1">MISNSAASTQPTDELDLLQLDPHFNQIFGDPFLPQRNLSYDNIDSFMLDEPIFASPNPNVPSSPESIFNSPPQQQLPNHFDLTAFNPNNASSLTNLMTTFTGNSMLPSLASLATNFSTSNLVSKLSNSNNFNLEINSTNSTDAVNSISSPLLMKFNNSNNINKKVEKKKKSDKRKKLTAEEREAKIQERILRNRQAAQESRDKKKEYVSNLEVTNENLSTQNVQLVELVKQSETQNQNLLSLVQSLSQELDRLKRNQSGLPPSPSPEAENLLGYGDVSSLTLPEPLNSTAHVIRNPAHSHRTAPYTLPSNNNYLSLIGSESSNKAGSCFVAVKKEPGLLTEIKTEPVSPPTSPESWTSLIERSPPPPSPSLINKEIASDAVITTLLTSLSFMALRPNSGLFARNLWSESEYGFKRNNWKKEKESLGISPRFHSILSPLKEERPLLRKRNRKNTEDLTGTLSNRRQTFYYLIALGELCKFLWKDDFKEQTAGWRYWRQRALDLRNIRDELCHNPSMSFGNPNNIYPLETDVRKNLTVLCVEKANALEELKIYLERDFLMGDTGGGNFFDKKKQVETIVGRDLRRRGLDKLIDNQEQEEKRNIIKFDSDLKTKRLKKKQREEGKKKTRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U386</accession>
    <name>A0AAD5U386_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000169">
        <property type="protein sequence ID" value="KAJ3222577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U386"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="358" mass="42645" checksum="3F5A68F536132713" modified="2024-05-29" version="1">MTNYVNETSIDTLVRAKRGLLRLEQIGQKNNIKVTDSDTFNFCRCLSLFDSEDRLNFSMPAKYDQIWQFAITDTEHYDAICYYTSSDFNKKSTRFIPYDPLSDLFHLKEKRQTFLQYFLEKFKVDLMDELSVNSQHSLAKTEQLNEEEPNPQQQIMQQQQNIQQQQNIQQQQNIQQQQNIQQQQNIQQQQHIQQHQKIQQQQTILQQQPSQQHQQQLQQQIHQNQHIRQNHQQSQQAQMHFQQNPVQHHHQQQQYQQQQAIDVDEQQVSTKPLQNLNDLMFDIPASSWNAQISNPSTPGDSMDNNSMYPFIKNSLDDIDEPNDIFSCSFEGCEKVFDKKWKLKYHLGVKYKIFILIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3A4</accession>
    <name>A0AAD5U3A4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">enoyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="8">1.3.1.104</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005744</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22564"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.104"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.104" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000462">
        <property type="protein sequence ID" value="KAJ3216758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3A4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141148">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08290">
        <property type="entry name" value="ETR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051034">
        <property type="entry name" value="Mito_Enoyl-ACP_Reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43981">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43981:SF2">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="411"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="11">
        <location>
            <begin position="22"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3216758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="436" mass="48411" checksum="159F56022BBBEFA5" modified="2024-05-29" version="1" fragment="single">MKIQKISRSCYSTHALVFEKYGSLDQLRLKSLNLKKPSSNEVKVDFIASPMNPADINQIQGVYPILPNFIETEHGKLAIGGNEGFAKVTEVGDEVKNLKVGSYIFPNVNSFGTWRESAICKESDLISLNIKEDSVFDPLLAAALTVNPCTAYRMLLDFVTLEKGDVILQNGATSGVGQAVIQLAKIWGIKSVNVIRNRFILFDMLESPKFLLKKDKQSDCLKVLKNLSDYNDVKIDLKLEDLLNPSIAADSQLNTEEFKFDDLRPLFSKDLRTTTILVFLIWSTSSLAYSMFYSFLPKFLISIPNYFGPELDLIVISLSGIPGSVIASKLVETELGRKGTLFFSTIFTSLSIFFFMKVKTTIFLLICNCTGAFFSNLMYGVIYSYTPEVFPTSVRGSGCGIASSLNRVMGIIGPLLSGYLISFGCELSMYICVIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3G7</accession>
    <name>A0AAD5U3G7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase C39-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000140">
        <property type="protein sequence ID" value="KAJ3223189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3G7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042209190" description="Peptidase C39-like domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="47312" checksum="D51E6494D29EF42C" modified="2024-05-29" version="1">MKLLHNLIVTLIFTVSYTNSRTIPKRAISPATCSQAAADKVLPTTRIYSFESKIQPFYQWMNNYGYCAEASLLQAGLMNGQFSSQYNMRSIGTPFNPIYSQTGKKKGIDIYSQLVMDDGIEDAKPGLSNNLGVAASNYLLTYDSFDSFNQKGGQEGYEDYMIWIKKKFVQGDTVIIGALETNSPPYSHVVTVLKIESDYPLDDGKYHADDVIWFDDHGLITKASNDIKSDWISNPSIPPAPGGQNEGYTFDDLKKSYGDEKTYQIPVPQSGFLTKNYAYAINGIEDSTKATLPITLTISSKQNSKNTDKPVDSIAGNNYEHPMIGKSDDGNSKTNEAPASADILDFNGVVHKLVKGQKYNLYKYDINQYPLIGKLKKIPVENFNLNRDMADAYISFTAKSDTFKFKFTTNSFTTVVFRAVLQSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3H2</accession>
    <name>A0AAD5U3H2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001824</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000156">
        <property type="protein sequence ID" value="KAJ3222860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3H2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041992024" description="DOMON domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="41173" checksum="26907312AAF887AF" modified="2024-05-29" version="1">MKLLTVIISTFLATFATSQTGFNSEVTEWASAILEADGQPSFRIQVRAVPNSPGLADISLIGAASLGWIGIGTGSKMDGSKLDICWPTSDGTSASLVSKLGQGHNVIPLEETLTLNTVESKVHQPMENVTDFPIFVCRYTHQLPEVLPTEFMWAIGPQVPASADAIGAHDMGKYGPFSAKQLFSIAAGKQIVVPEESQAKPVASTLTASTTTAPTTSPSATTEWGDVWLFEYRLKQFKQNHTLSRYIWMICIIGTAGGAALRLAELHKSFKVAGKKKSGITSILMMLVRSVGMRLFFITASIILRLACEFQGTELSIQINNIFINFDTSINSFTLFDLLLSKIEKADLKTKRLNCSNITTPSTNSGFSSFNNTNSESVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3H9</accession>
    <name>A0AAD5U3H9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000330">
        <property type="protein sequence ID" value="KAJ3219725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3H9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="24"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="77" mass="8908" checksum="9B37876C130B4EEF" modified="2024-05-29" version="1" fragment="single">MPYCKTSTNLKLHYELRGSGSVKILYIMGINGTLNSWHFQSMHFANERYQICLFDNRGVGFSELGKNERMTTKQMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3W8</accession>
    <name>A0AAD5U3W8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Myocyte enhancer factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MEF2A</name>
        <name evidence="10" type="ORF">HK099_005388</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000416">
        <property type="protein sequence ID" value="KAJ3217643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3W8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="9">
        <location>
            <begin position="333"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="553"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="620"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="779"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="565"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="634"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="779"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3217643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1040" mass="118228" checksum="3918ED36834AA0B4" modified="2024-05-29" version="1">MGRKKIKIKPISDERSRQVTFMKRKFGLMKKAFELSILCDCEIALIITSGNKMAQYTSSDMDKILLAYTDYQGTPELRTNADFLHLVDKADNDDDHFSDEITPTLGTFKSPKSPASTGSASKKSQQQLSPVSDSEIITSFDYTLSYPNTFQNTKLQSPIDNLPSVNHESNTINSKKNSLSHGNENVSLNVSPHSTAMNTVSFKQGNMFYSAQDDFWMDPSTTANNFNLPQTYFNLTPRINRPNYIPQMGTSQTTSENLNIFSNNVEFLKTSTIHNYNKQVNGSHTNKRKSSKSKVFNNLNNIQSTKNFLSEMTRIPSSNINYDNIKPSCFTSSLLIDKELNATITNLIKDYINTWYFDISQDLEFQKELLSLTASIVGRLETRLRAFDWTTFCYIQLPSIFRQHIQDYRNCKKKVGTVYSGLKNISEMFHGCQPHFALENEENQREYLRNLSEFLIETFLPVEESGEMVKYLLREILTNVVLINLVEKLSDPDYLNQLIVDALKAPESGDPPSQSAASNNFGRQITERNGSFLFNNTQIPVLDVQDFETPKQQSFNKMKAHKFSHSSTSHQKTKSSLSTPGSDNNIFTSNLNLGETVTSGMNKITGGLTKITTGLKQLVHNKESSTSPSIATSEKQEKLDKNERKKKKWKEKNNTPNFGDHPKLKSSSVLTLDVEKKKKMHKSYDDLDFCSSPQEINKSSAIFGNTSEKLAGFHNVPTFNSMENCSGSSKEGEHYMRCKVNSDNDIDQFKINCDSFNHNTSESEGSPWSDVSPNIFLSSPSPIPNDTNFSEGYSTNEENDLLRPSSTSNTSIRLHQKLIKESGKGFLNGSVNCDTSSNYSTESEKVLKDPNVETKIDEIKVKRVIGEFVTISDQAMFDKQKDFNCFNLKENISAVKNFYLKYIKENEEVELTLLKYNLDIRFCVMKINELITEEKICFYLEKFRLSFWPDVADTSGYDNSLRTSEEKLQTKLEAVESVKRLLPQVLSYWLGCDVVENSILEILEIFQDQYINKHLIFVLIDSIAVQFVPEIVEDEIFDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U413</accession>
    <name>A0AAD5U413_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000756</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000119">
        <property type="protein sequence ID" value="KAJ3223736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U413"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05379">
        <property type="entry name" value="CAP_bacterial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157:SF1">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042181931" description="SCP domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="53"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="355" mass="40271" checksum="1C732BEEAE8DF8C8" modified="2024-05-29" version="1">MLSKISIVVLALTVSANQQGTRDRPSGNYKPISGSSYGAQAPETQICDLLIGVNNFRARNGLSPLIGDVRLDQAARRQCNAMAEYNNLDHSADGSKLGDRIEQAGYNWGGVAENIYNESGYGGVDQQRALEGWINSSGHRENLLGDYTSIGHAYCETGNTVYWSQDFGSGDVDPQNSYSCNPSDYEYEASPEEEIEYVHSEREPSYEAEQVESEREPRYRNQEVESEREPRYRNQEVEKPRYRNQEVESEREPRYRNQEVESEKEPKYKTKDIKDEYISIELPDNEVESNYKLDTYAQSEVSPINASYPESETLPIKYGKHGRPCKATSYGKKSKTSNNFLKGAKVDVSHAHHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U475</accession>
    <name>A0AAD5U475_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase arih2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARIH2</name>
        <name evidence="10" type="ORF">HK099_003951</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000269">
        <property type="protein sequence ID" value="KAJ3220839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U475"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="18"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="22"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="388" mass="44898" checksum="47A073FBD89A6F2B" modified="2024-05-29" version="1">MQIYSADLEQDYENLDYLYSRCSICFDEAHDFCLSRCRDQFCEGCFQRYVRETVKSSWGHATKLITCPVCNDVLTGPEWKCFLDDETIELYELYNQPYRAITRHCGECMIELKIAQKPIESPKERQSQFSEIYELISNLFKESKYKNKDSCLARFQADFCNEFSGGGNGSKSILDIYTNIMIGLGKLVGIRCSESGAFKEGAVLTLKPELLAKITLISTMFIPLETVESKWKKLQFLHISNFPKVLCPNCEDSLCFSCGESPFHENIGCSKYMKHIIIKNQDTEKVANFKWKLENSKRCPQCKIMINRDEGCNKVDCTYCGYIFCWSCEGKFENGNCSFYRCELDRTRSRVQKAEEKEKFSTSPSKTKAFTELGVPNIFQIEEKFLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4D4</accession>
    <name>A0AAD5U4D4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000104">
        <property type="protein sequence ID" value="KAJ3224114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4D4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22710">
        <property type="entry name" value="X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1 XRRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22710:SF2">
        <property type="entry name" value="X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="312"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="706"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="719"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="912" mass="105501" checksum="1A67CC317A17404F" modified="2024-05-29" version="1">MRFTKLFVVDEIFPGKYSNREIQLMEEKSKEEKLISTEEPEEKEIVLNEIKVSLKESNENSSIKDENKNSSILLNKISSQPRKEILRLGEEKTSSRFNYKNNITQKDLNEKKNFIPIKEFLMTEQLDLKKYQNENSRNLIDLKKLEKFKKSKIKKNGVEFDKYFEVKNLLDGFLILNHGCTDYPEEVYTVDLTGLDLESIIEEDLELFTKLHSFKAGDNKLNFEKLGAFPNLRTLILPLNNIDYLDFYVSLKFPLLEHLDLSYNKLYVTSISVLASLPNLITLDLTANNLKYLPDDISDMREWWKNATENEQLPLDDNSNGKHERSLSLALSDQDDEIDEKKGTTIEEEQSSEENSTINKSAEKISSQKKSESKNSFGMESIDKYGDNSILNTCGSFSEFNNDIYEQRKESQKKMHRYQGFPRLEELRLANNLIATLEDLMGLVALPSLQRVYLEGNTVMDPRKRIGLQKDYNIVHDLSLSYGIEVCDGIYQKEKLGSIDENYYKLVQTNINFNKILDPVSENKSLKQIKIIKKKDLKKNFIGHMLTKNKAGTILHSLFKKGVKLFPHNVQNFETLKDQKSKNLINGGRNTRRKYKYTDDDIAKMIQIGRIFTLKELNSLTEEEDCNIQKNPTAEQQKDSDLLNNDNICDTTEVSQSEMHIDNQNNEIECEVQAIDENEAQNFSKEYDVMYDSKQVDETFITGVHITGGNEGAKPLEEPNNDFSDDSEDDLEEEEETYDTSDLPVTIQASLKALRHALNNPVSYERVKEASYVQPTFAYKRKLRDVQSRYRYNKKLTLPILLKANLLFSFSLPESLRKPDNFSHKIPLPPQTLPPIPPKLHNVRDVIPSNYFRPNSKFNKNPNFNNISNNCSSGTYKNRTLDEFEDMKNLLSNVDEKLDIIETKLGKQENFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4P2</accession>
    <name>A0AAD5U4P2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_008507</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the VPS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000094">
        <property type="protein sequence ID" value="KAJ3224402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4P2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1130:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="10">
        <location>
            <begin position="754"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="9">
        <location>
            <begin position="886"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="575"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="621"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="639"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3224402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="989" mass="113599" checksum="1D555C3D221886B3" modified="2024-05-29" version="1">MLIKTYVEIDPRVKPLIMTVKHWAKSRKLNDAVKGGTLSSYCWVMMTLNFLQTRTPPILPSLQEIYSSQLKSNPDSVQPTIVDGVDCSFYEDLESLQTFGNKNFESLGSLLHGFFRHYAYEFDYTTQVVSVKHGSLLTKNEKGWDKDVERLYRFLCVEEPFNNQRNLSNSADAISVIGIRNEFRRAANLLASTGDLNIVCEEYIFNSNFNSYYYNHHGNVGNFYARTQWKKFGNQDHYFSRHNDGRRPYSSTFFQTYPPEQHTEFRSKENFKDMNNENLGAYVYYNNLPKLQSYQISPFPVGSDIKSEKTIKPRSLNQDAKNNNSKKFSNFTPQFNPSIHNIYWNLKNINTQQLPHEDNQYSRLQDNLLNHHYVGGDLSTTTNRNFNGSLYKKRITNYNRNYEISKTKDDFNVGDTTIREYTGNGYGYSTISSNSNRKDEHQRLNQQHKVQPKVKPLLQQQRPQPQIISTQPGADLINIKNIDENKISSTDNKYNLIELSKDDQNLKHSINAALNSNGNFFLTNNGNAKLEKKRTSTKGMLLWANRSQRHSPANNPELESVQTMFQGLFNLKKSEQKNNCSSTKKTKSHLKNGSISNVNFINDVKNPKHTSNKNSNNAVNDSKKNKEDKFNQQNDKNSKNTNNHENNFNTDFNNKKFTDNSKNLPKNSTINSFFVQPLNRSRSNSLPSVFSNNSLMNSNSLWAKEEYQQVARPSSAMMIKNEHMINNDLLCEESNSSDDDENYVINNHAEVIEENKTAVSISEEAALVSSEQDSDRIVSVAPPPMSYRDAAALEREIVENQAELYSLVLAIEHLEKAYIRASVTPKEYTEQCLHLISQFKTISQLLNVENLPLFLSSLNSTPLAALKRLQIGVPATFEHKTEVNKNSAKHVAETVQVFITLMDSLKLNLIAVDQIHPLLSDLILSLNKVDTLDGKYDEEKEKIKNWLIELNKMKASEELDDDQVRQLLFDLERIYGTSAHTEFHRQLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4P7</accession>
    <name>A0AAD5U4P7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003594</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000237">
        <property type="protein sequence ID" value="KAJ3221311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4P7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="7">
        <location>
            <begin position="112"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="621" mass="69360" checksum="8072F063603B8A1F" modified="2024-05-29" version="1">MAIKFSLNSTDIPTGVSCPANCGNGTCALPLQCICNEGYTRDVTLFQNKQLDCTVPVCQTPCGYGECISPNVCKCQKNYYGQDCSMYSLELQTPGITYQIYNGIIGVTNVVLAVGAVVAFIGLKYSSFTKVKKFGLDLLQFTILGSVIGHAGVVTGMIFPSIATCTLKYILYIIGLTLILSSLFIRSWRVYYIFERPTSVSSSTIITFKKLMMIMLFFVAISTIGLIISILSDIPSTKTMTDIDMEYFYLACTIPTQVGGIMGLIIIALNAQLSKSVPADFRESKAFIISYLIFFILVCQTVAEYLKYSETIKTAIFGMLSALLFSVPTFFIVIPKLYLVLSSKSRKSTDPNKSSQSIGTVSTSFASLTLTPIKKLGNEVVMGNFAHLTPGLLGKWTRKVAYYDRKTNLFTLIPMVSLEIEERVLSCFQINGKNSKLVYKPTKKVEDKVGNMNFNNETLKKLEPNKNNVNEKGFAAHSDDESLFKETVEFMIICGGESHRVLLVDEDKEQIKLWKSLAEELSKSSNRAAEQPRTDILMDGQTFFFQVDLELFMEQNEKKMEKNCLTYTLKEVSQTIKEKVTGTQKKKNINYNIAQVDEDDEQIKLWKSLVEELSKAATEPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4U5</accession>
    <name>A0AAD5U4U5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_008583</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRN7/TAF1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000096">
        <property type="protein sequence ID" value="KAJ3224339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4U5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070860">
        <property type="term" value="C:RNA polymerase I core factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042790">
        <property type="term" value="P:nucleolar large rRNA transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048538">
        <property type="entry name" value="Rrn7_cyclin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048540">
        <property type="entry name" value="Rrn7_cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033599">
        <property type="entry name" value="TAF1B/Rrn7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31576:SF2">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20645">
        <property type="entry name" value="Rrn7_cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20644">
        <property type="entry name" value="Rrn7_cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Rrn7/TAF1B N-terminal cyclin" evidence="10">
        <location>
            <begin position="195"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Rrn7/TAF1B C-terminal cyclin" evidence="11">
        <location>
            <begin position="318"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="604" mass="70410" checksum="7748C1CEAD2D1FC8" modified="2024-05-29" version="1">MDQNSKNYNKKICLTCRSKKFKKAEDHFVCSNGHILHSYLEIDDELDVGSQSVNLRKIKLKKLSKNLYESENDSDLNSVNKNLQNSSENQKVPKHLILEVFAYALKTQVKGLIKNNNFPEILEVSTISSFFNEFLVIGDGFIFTIEIKTFGETETQDYTYEDILFNEEGEQFLKSDLESIISNKSDIKKTSALISQELFDDNDIEEHTLHEKRKKSIQEPFLTKKINELEVFMFGRHVSTELNNLDKCHLHPTYAPAIIYLACSWLRIPVLLSDVFRWIGDGTIPFFSSFTKLPRYLLDALLNESVYIYKLRRVEQQLPTLEHLKRVTIALGKFYNQNYEIKLPSPLNKPLFRIRLIVELGLPEMHEGFKCPDYSEADSFSAVSEHFVEKEFSLIGCSIIAVCIIVYGMDGTLRYDLESYPFLANIPKFNDWMEQLIREKKYTKGFASWSQNDFHLSESETIQKYLNFCEDELFWANGKNKGLQEAFLSLVEKRKQQKKDEKCVRKSQKRNTFKPIEREYFMGGKPVKALGEDFIGFPPKKHFQYDQFDKVGELHQSLEYLLSYLIEIGGIDRARLELVFYNFIKTLEIESLFNLDAILNNHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5S9</accession>
    <name>A0AAD5U5S9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SPCS2</name>
        <name evidence="10" type="ORF">HK099_006918</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPCS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000063">
        <property type="protein sequence ID" value="KAJ3225377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5S9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009582">
        <property type="entry name" value="Spc2/SPCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13085">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13085:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06703">
        <property type="entry name" value="SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3225377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="199" mass="23018" checksum="F0E5BF94451582F5" modified="2024-05-29" version="1">MSKSLSSKNKMNSTTSSKFLQLYETTPVTAEKWCHGDYKRGVDEAIKNLLTLDLGYTQDNFLKDAYLALGYIACSFALYGTYICYYVQMPFQESKPTLYVCVSGYFFFSFLMQLFSWFVEKNIIFQGFNKELNEKIVIESKSSKFSDKITFTITRNKSIMTTTSFGKWFDKNGVFSAADFKDDFGIYVTMDETKNKKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6C9</accession>
    <name>A0AAD5U6C9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biotin holocarboxylase synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BPL1</name>
        <name evidence="4" type="ORF">HK099_005960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6C9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin--[biotin carboxyl-carrier protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03144">
        <property type="entry name" value="GATase1_ScBLP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019197">
        <property type="entry name" value="Biotin-prot_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835">
        <property type="entry name" value="BIOTIN PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835:SF5">
        <property type="entry name" value="BIOTIN--PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09825">
        <property type="entry name" value="BPL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="434"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="722" mass="80913" checksum="E1D17667FED42D97" modified="2024-05-29" version="1">MNVLLYTGNGAAKGAIYHTSLMLKSLLSKNYDIMEVDANTIINEPWQSTTALLVFPGGRDLPYLNDLSQKGQNYIREYVKTGGNYLGICAGAYFGSSRCEFEINRPHYEVVGERDLSFSKSVAKGSVTANFVYGSESGSKAMAVQIDKNMLGLDLNEQFSSEIINLYVNGGPYFEYSSEAKNERILAYYLIPTPNSEPKRLPAIIESNFGKGKAILSGPHLEYSPNVITQTGYRSSLNSNTSSTLSDHVHLLTLLPSLISTEKSRLIFLRSILSLFSLKLNPEEVFDEVLNEKLFPKITAMSLTGLSSYGDTDVKNLLSYLNENSQLSQIFENNEGKTKATECLFFQDEFKFLFLNKSNANNITESEINTTLKNSNLINDEELRNNLLIKIYYENFTGDENELNNKLDNAKISEKVDEKSLTHFNPNYYIEKLKNLQKTSGKISFGTPILYGEVVGSTQTLLEKNFKLLRNLNDGFVCVGSHQIAGRGRGRNSWISQTGCLQFSFVLKHENAGSVIFIQYLVGLALVESLKAMKGMEDLPVRLKWPNDIYAFSPLAPNKNLTDLRNYKKIGGILVNSNFIDGKFILVIGLGLNVNNPEPTLSVNDLRKWFCPDIFPLSQEEVLANFFCKFEEIYRVFNKPDFPPFANMELSNQIVTLSADSIRENAILYTNKINQEVKVKITGIESSTGLLKAVGLNDNQTYLLQPDGNSFDFLQGLIKRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6J2</accession>
    <name>A0AAD5U6J2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sn-1-specific diacylglycerol lipase</fullName>
            <ecNumber evidence="14">3.1.1.116</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_005261</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:33276"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="14"/>
    <dbReference type="EMBL" id="JADGJW010000040">
        <property type="protein sequence ID" value="KAJ3226264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6J2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046340">
        <property type="term" value="P:diacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF8">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041953219" description="sn-1-specific diacylglycerol lipase" evidence="16">
        <location>
            <begin position="20"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="17">
        <location>
            <begin position="363"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3226264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="730" mass="83728" checksum="BFA7F0F988F3ADD4" modified="2024-05-29" version="1">MLTSIILLCVLVPMELLTAILSMSGTIASKGPRKYVAPLIHGHIILLFAELILHSFGFYAIYGTNSLYTVKDDNCKVSAKSQLNLLYLVVYFSFITLFLWLTVLMGLLYLSRKKNKVANFHKFQELWKNRLRWLVYYCKKFTGFDANLTANSNDVISDVAGVLADYFLDVDWTPSDIAAGLILLKRKQKSKAEELYERTRMEAMKAGIAEKRANTILEKLFDEKANLSAETLNITEAGSGVYKVERNTSEVTLNNEQSVEEKVSFTGTDVYMQDDEISIVPDKNFLNVPLENTKVPLYVTKTENSILHKEDIPDIIHFSKYMEMMYSPTAPKEADHVLHFNDKNDVFQSPYLVALDHDWETIVVAIRGTFSLADLLVDLKIEVMEYKIPELGENVPTQYTHSGFFKVASTIMADINKENLLKDLRDENSKYSHYKIVVTGHSLGAAAGALLTYMLRSNGFLEAICYAYDPPGMLLTYESSVYFEEFVISIVNGDDFVSRLSLHSMELLKLDIARVLNNCDEHKWEVLGSSFMNFYFGRNRKFRPKFPQLGRKSSSVEKAENNDAFSVPYSNRESFEVSDEVKSPFDVQSSVDVLSIPKLYMPGRLLYLEKCRMWDDGKDDLSFFSTRHFKKNSNQLSKIFPWLKDSFKDCNNDCDNLPFYFHAKTKTNEPISFRPSIKGKYAYCPRWSDREEFSKVLISKSMFSDHWCLPILLEMGKFKIGEDIKVQIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6P3</accession>
    <name>A0AAD5U6P3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA repair protein rad50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RAD50_1</name>
        <name evidence="12" type="ORF">HK099_007430</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000072">
        <property type="protein sequence ID" value="KAJ3225055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6P3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="11">
        <location>
            <begin position="17"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="177"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="332"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="409"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="515"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3225055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="700" mass="80282" checksum="998A96E9B4E35400" modified="2024-05-29" version="1">MLIRGIRSFDPNDTNVIGDLPPNSKNGAFIHDPKIAHETEVLAQIKLRFRNINGQEMVVTRSMSLTQKKGGVTQKTLEGLLVHKDDRGGTSSFSSKCGELDAELSNNLGVSKAILENVIFCHQEDSLWPLSEPSVLKKKFDEIFASTRYTKVLDNIKSIRKEQNIQFKIDEASLVHLKSDKEKAAKIRNQCKRTNSQIKVARERIEKLEEVGIDEVQKQMSEIFEAQQTFGQLKNRKVELENEIERVQKNIENITAYLDGKESDESDEILQKKLDASYQNMNENTSKISNLDSQNKKISAEISSCEEKLSEKRLHEGKLLAEKEVYAEFITVDDFEKFMERLKAEIKDKSEAHESITRQMKEAENKLLEELQKLKSNYAKFEESKKNNKKFIDISKQKTNEYTLKIKKIQVTQHDIDDMEQKLAQEERNLQLFMESFSQFDNEAKSKKLQNELVEIEWKSNEISGRLGLLNLQVESRAKINLKKAERDGKESNLKRSLQDAENEFVALLGHMPSLNEIERELELKLREKEAFLKREEDALHIANKELSGYETRISMAKSNLQKSRATLIERKSLISQNCEDGDYLAAKAKASKEVDEKKDSHATDVSNSNVSQIFDEIRRNMLKNILASIPANIKISELALETAVEKNKTIGGLQTAWDDIERILIEITETEKRLIDNEASKALKENCILDVSSLRYFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U789</accession>
    <name>A0AAD5U789_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000059">
        <property type="protein sequence ID" value="KAJ3225507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U789"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="126" mass="14314" checksum="39970361F16FE434" modified="2024-05-29" version="1">MQLLEVHAITGLLGVLIESAFNAKKITNPDENFSLLLGFNEINWIINESFIVAYSYMKLETAVFNESLKKALRITLGFIFVPFAKLRINIGVLRVQFNVTNNEQISFAHSLAFIPWGFAEVRKATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7I4</accession>
    <name>A0AAD5U7I4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000161">
        <property type="protein sequence ID" value="KAJ3222749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7I4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="197" mass="22100" checksum="B2DBE5D71AC8A4F1" modified="2024-05-29" version="1">MNSSDPIAKDRAVQEIWHQINLGWEVTKLLEIVIIPYETKMVWLMQAISAAIMRILELVVNFKIVNGLNSKQQVFNKSLLVVTVLSAIGVLGGRIYDVLYFQILEASEIRLGMALVSISGLLQAIVCLFHIVKTLRQLDRKHSKVFCILQLQAMRSVFIQFIDLAYKKEDFQNEFSGPVADTGASGVNAIKTKSFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7P0</accession>
    <name>A0AAD5U7P0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Dynein heavy chain 7, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">DNAH7_1</name>
        <name evidence="20" type="ORF">HK099_000787</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000002">
        <property type="entry name" value="Dynein axonemal heavy chain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000003">
        <property type="entry name" value="Dynein heavy chain 12, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000002">
        <property type="entry name" value="Dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000223">
        <property type="entry name" value="Dynein heavy chain 3, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000044">
        <property type="entry name" value="Dynein heavy chain 5, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001328">
        <property type="entry name" value="Dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000006">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000362">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF70">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 2, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="12 17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0243">Dynein</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="14" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="19">
        <location>
            <begin position="2241"/>
            <end position="2276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="693"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="2816"/>
            <end position="2878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3227682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="4016" mass="458526" checksum="3E67A96A8768F7BA" modified="2024-05-29" version="1">MSEPKKKSVSSLSKAWDSSLSYLPKDLEEGTPLALFQTYQSQFIHNSNKSIPPNLTLPDNSLFQNGNRLQPKLQMQKKLQSLTNPPQSQRNFEKGSKKGRETFRTTMVNVVMHNTAHEKFVSADQLPAISTNRPVTAQDKDMTQRYYYYITNGIDTQHVAEMKNEWLKNVLDLLPDNLKNQHEDALQILSSEMREDYHMSVKKAIVDFVLKDPRDKNSLDDKKKPTQEDFLNIRSSAPTWQNDYKVSLQHIKDNLFINPTITAIVDVWYKFHDLRLFDLDAILLKNGSFELRTFKTMVSQKLEKAHEKLMTTWYPTILNIFYQGSKKNEWSAISADRMQVFFRMISFLLADQLRSMIRRSLIDFVAIFDGNVVTTALMLEGSQPLSFIVRVVLDDTNIHLDPTNNEVQATIEAFIDQILVALDHIPKIETQLFSNMANISHIANTSNQPATKGNAIGQNLKPENCINVCFKKTFPNFVEELRQKLKKNLIRQLEAPTNYLKEFERHKRLIDKSVYQEVHDFLHSEDITQEKMMEDVIKWKHIANNMIANAYPHFVQFSLIELYCEDFLKDLSDRAQYQAHLILEKLSIDNKTTNLGVCKTFDKISEKILTLPTNVEDMVNLQKFIDKVRHTEMRSLENEVEEAKKRLNFLILYSELKREDYDVNTTLFQWPQKIPLAISEGENLLLRSRLSNQEELKGRREKLSGELEGYTRQIDEYYQFGDFAEINKYLKSAQKLQSRLELINEKIMCFNREEELFGWETTKFSTLQESITALAPYLSLYQTSVEFQKCYHAWMSGPFLKLDPEVVETEVTNMWRNIYKLVLQFENEACPLEVAEITKDQIERFKVHLPLISTICNPGLRERHWKEISAVVGFRFQPDESTSLEAVLERNLADHMPNLEVISGAATKEYSFEKALQKMYVEWQNIEFVTIEYRDTGTHILSSVEDIQTLLDDHIVKTQTMRGSPFIKAFEEETHIWEEKLITMQEILDEWLKVQSTWLYLEPIFSSEDIMRQMPVEGKRFASVNKTWRDIMAHCNSDKHVLKVCSMPDILTKLKESNIELELIQKGLNQYLEIKRLYFPRFFFLSNDEMLEILSETRDPTRVQPHLKKCFEGINSLEFEENLDISGMYSAQKEFIKFIHPISTVDACGAVEKWLYSVEKSMVTALRDVLAKGYHSFPNFTREEWVLNWPGQIVLAVTQIYWTREVEAAFAEGKRESLKAFADVNTERLSKIVELVRGNLSRLTRTSLEALVVIDVHARDTVAMLEEGDTKSVNDFAWLSQLRYYFEKDSGCIVKMINSVQKYGYEYLGNSGRLVITPLTDRCYRTLFGALQLNLGGAPEGPAGTGKTETVKDLAKALAMFCVVYNCSDGLDYIAMGKFFKGLASAGAWACFDEFNRIDLEVLSVVAQQILTIQRAKAAKLDTFMFEGTELTMNPTMNPGYAGRSELPDNLKALFRPVAMMVPDYTLIAEISLYSFGFVQARILAVKITATYRLCSEQLSSQDHYGMNCKHFINFIFIDYGMRAVKSVLNACGALKLKYPSENENVLVLRSIIDVNLPKFLSHDVPLFKGITADLFPGTTLPTPDYQELTKSIEGACNKMNLQCIPEFLEKILQVYEMMLVRHGFMLVGEPFAGKTSSYRVLQAALTDMNKNDINKEAKVQVGVLNPKSITMGQLYGQFDPITHEWSDGVLALTFRNFASAQTPDRKWIIFDGPVDAIWIENMNTVLDDNKKLCLNSGEIIQLSSTMSLIFEVRDLAVASPATVSRCGMIYMEPVKIGWRNTLLVSWLKKDLFSEEEKKLIIGHFDWLVAPCLTFIRRNCTEIVDSLDSNLVSSLINIFESFYKEPFTETSDERTLTKYLQGIFLFSLVWSIAATINETSRNKFDNFLKAAIAGTPEVPQPTQFSVSTAFPNESTIYDYIFDKSNCKWKLWTQTIPPDFTIAQKAKYDDIMVPTLDTARYSYLLKMLIRNNHQVLFVGPTGTGKSTYIRDTIMNGLNKEIYIPVFINFSAQTTANQTQDIIESKLDKRKKGVFGPPMGKKSVIFIDDLNMPAREVYGAQPPIELVRQWMDHDGWYNLLENSTQEFIDIQFVGAMGPPGGGRNTVTPRLLRHFNILTITSFDDATLNRIFETVLEWHFTTKNFSADIKAISSSIIAATRGIYRGAMANLLPTPRKSHYTFNLRDFARVVQGVLLATAENVDNVNKAVRLWLHEIYRVFYDRLIDDEDRDWFFNFSKETIKNNFNLDFNKVFSHYDANADGIVTNDDIRSLIFGTFMSQKEIIKSYNEILDIEELTLLMDKNLVEFNQLSKKPMDLVMFRFAIEHLSRINRVLQQPRGNILLVGVGGSGRQSLTRLAAYVSDYQIFQVEISRGYNYQNWHDDLKKIFKMAGGQGKPTIFLFSDSQIQQEAFLEDINNILNSGEVPNLYAADEKQELFELVRNDARMSGRVPDGNPTALFAYFVERCRENLHIVLCMSPVGEAFRVRLRKFPSLINCCTIDWFKDWPNDALELVAKKFLKDIEMTDEVRQSVVEMCKHFHDSTIKQSANFWSSLRRHNYVTPTSYLELIKAFKTLLHQKRTAVSKLKYRYVNGLEKLNFAQSAVQKMQIDLGELQPQLLIAKDETDKVMAQIEIETVGVQETRGIVQVDEEIASKKAAEAKAIKDDCESELKEALPALAAAVSALDTLKANDITVMKSMKSPPAGVKLVMEAICIMKDIKPVKIPDPAGSGKKIEDYWGPSKNLLSDMKFLENLKLYDKDNIAPAIMKVIRAKYMDNPEFDPEKVKSASSAAEGLCRWVRALECYDRVAKVVAPKKEELAKAESALAEVMKSLNEKRATLKAVEDKMAALDDKFKSMVAKKEQLENQVDSVSKQLIRAEKLIGSLGDERDRWTETAASLDIKFTCLTGDVLVSAGIVAYLGAFTKLYRDECVTEWTFLCKEKKIPCSEDIKLTNILGEPVKVRAWILAGLPNDSFSIDNAIVISNASRWPLLIDPQGQANRWIKNMEKAKSLQIVKLTDSDYLRTLENAVQFGTPVLLENVGEELDPVLEPLLLKQTFKQGGITCIRLGDSTVEYSPEFRFYITTKLRNPHYLPELSTKVTLLNFMITPEGLEDQLLGIVIAKERPELEEMKIQLLLQSAENKKQLQEIEDKILEVLSSSEGNILEDETAIQVLSSSKILANTISEKQATAEKTEIKIDEIRVGYKPIAEHSSVLFFCIADLANIEPMYQYSLTCSIEQSEKNSDLEVRLSNLRVHFTEALYCNVCRSLFEKDKLVFSFLLCAAIMKAENELNTDEWRFLLTGGIGVGGTTLENPDTTWISDKMWNEMDRLSELANIKSFSLQFTAHVEEWKHIFDSGDPQDMAFPGHWQSDLTPFERLCVLRCIRPDKMTAAIQKFILEKMGKRFVEAPPFDLASSYSDSNSCAPLIFVLSPGADPMTGLLLFAESRKMGGSRLQSISLGQGQGPIAANMISTGAQEGNWVVLQNCHLAISWMSTLEKICEELNPETTHKDFRLWLTSYPSDKFPVTLLQNGVKMTNEPPKGLKNNLLKSYNSDPISDKSFHEGCKKQEVFEKMLFGLCFFHAVIQERIKFGPIGWNIPYEFTDSDLRISARQLRNFLNEYKDTPYDALSYLTGQCNYGGRVTDDKDRRTLMTLLQLYYTPEIENTSQYSFSPSKIYHIPESASYKDMLEYIPVLPIQAKPEVFSLHDNADISRNQLETDTFFKAILSTQARAESGGGKSTEEIIMEVGSGMLAKLPPPIDTAFISSKFPTSYTESMNTVLLQEMIRYKTLVEIVRSSLVNIQKAVKGLVVMSSDLEDVSSSMLNGSIPKLWAGKSYPSMKPLGGYFQDLLQRLAFFKKWMDDGPPIVFWISGFFFTQSFLTGCLQNYARKYTIPIDLLAFEYQIQTTKTAGVRPEDGQYIYGIYLEGARWNGELHSIAESHPRILTDQLPVIWLKPGDRTKLKFSDTYDCPVYKTSARRGTLSTTGTNYVMSMRIPTSVPEEHWIRRGVAALLALND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7W5</accession>
    <name>A0AAD5U7W5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000091">
        <property type="protein sequence ID" value="KAJ3224509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7W5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="65" mass="7910" checksum="CB20A4C9CBD6471B" modified="2024-05-29" version="1" fragment="single">MSYIYITGNVEDLEFTKAEMLGNYLSYNLDNFCIKVEPIKSELWPEHRKKIHKENNWEKRPAYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U806</accession>
    <name>A0AAD5U806_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U806"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="102" mass="11300" checksum="44AF0A151B813E52" modified="2024-05-29" version="1">MAVEIDFTRAASADGPRQNPIKRTDSLPLKTCLKGSKFNQEELTIFSPIPRKPTACFASTNALDLINQFDKLEDLSFNDAVREFLYVLNSPPASPVGEVIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8A2</accession>
    <name>A0AAD5U8A2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cullin family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001011</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000126">
        <property type="protein sequence ID" value="KAJ3223533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8A2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000001">
        <property type="entry name" value="Cullin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000006">
        <property type="entry name" value="Cullin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000002">
        <property type="entry name" value="cullin-3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="7">
        <location>
            <begin position="415"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="790" mass="92132" checksum="397449FC64EA4B37" modified="2024-05-29" version="1">MISSKGKIRGPKASRSSSNSESDFQEAWGKLEPAINQIYGKNASNLSFEELYRCAYNLIHKKKGERLYEGVKKVISSHLSNIEERLRVFCDTSDHFLKTLTGFWDDHTTCLMMLKDILMYMDRIYVPNANVSVVYDLGLELFRDINIKSVKNLLINTLLEKILSERKGCTIDHFLMKKTIEMLLALDISREKFTNRSWYHVEFEPHFLSASESYYELEGLEYLKECDCSEYLKRVEQRLKEEKDRIDRYLSHSTETKIIKIVENNLIKTHVTSLIEMENSGLVSLITNNKLSDLNLMFKLFGRVENGHLEMRQQIQLHVQKLIREINELHSGNFKTKLSNSNHSLNIPPITVLDSPIPPLQPPTNMQPNPIKWVQEVLNIKDKFDKILETCFERDKLFLNEFNVAFELVVNENPKFPEFVSIFIDESLKKSIKGKSEDEVDTLLDKTIVLFRYIAEKDVFERYYGQHLAKRLMHGKSQSEDAERNVISRLKVECGFHFTTKLEGMFKDMSTSHDLLQNFKEQTSQHASQVDISVIVMTSTFWPISFNSKSTLILPEECQKIIKKFEGFYLTKHTGRKLTWLTNLGTFDIRGEINMSPFAMSIIMMAFNSNKNSTAEEEEYIEYEKIKNLTDMQDNDLKKGLQSLSLGKYKILIRERRNPKKKDIISTDRFKLDVNFSSALNKIKIVNIQSSVVTGDMNFEKGSMENETDRNKTLERVENERKHQVEAAVVRVMKSNKKMEHNSLIGDVMKMLRIRFKPTVALVKKTIESLIERDYLMRDKNDRKIYHYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8G0</accession>
    <name>A0AAD5U8G0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000074">
        <property type="protein sequence ID" value="KAJ3224997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8G0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072:SF10">
        <property type="entry name" value="ACETAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46072">
        <property type="entry name" value="AMIDASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="50"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="673" mass="74505" checksum="41010CC541EEFD6E" modified="2024-05-29" version="1">MKKGEKRLKLTLEKIDINYPNPQKSNLILASKTISDLLKGITDRLFTASEILKVYTKTAIQLHYKFNFITEILYDDACSQADLVDLHFNTNKTLIGSLHAVPIVLKDDIDIKGYDSSLGCRCGTFRPKYMDSTIITILKLQGAIPFIKTNVSFHLLMAESNNTVFGQSINPLYQYISTGGSSGGLASCLSSFGSTSLVGVGSDRVGGLRIPSQNCGLYSLKPTSLRFPSATINNRSLCWATLPAVLGPVAQNLKDLKIIFQTLINSNPEFIDPSVTPIKFDDTSYKNIQEKKLRIGYFSHDGFFRSTPPCSRAVAKVVTELRAAGHECVEISIPNFTDAILLLCQLLTINLSAGCTSLTDLQELDLSQPIIPIIMLLKAPRRVIGKFFEKILDDQTAAKIIRSIGLGPGFSGSKDASFTNKIFFWWWYALKWFFGLGDRKDTRDGIDILKLISEKEDYQKNFNEIWSENGDIDAIVCPVHALPPLPSTSFPYICSGASYSMLFSFLDYPVGIIPNVTHVTPDDRIEDTLSYVHGRDVDESSSVFQHDASTNVFPLRPKHVPSHILPEGVNLMHDDLESNNISGTYTTPPIPPLPQEFFSNQNPVGEEQEPNTNFSVKTSFNLLGILGIEEYNSALQSGVLNGVGVGVQVVCRRYQEEKVLGVMKVIEKLKGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9D8</accession>
    <name>A0AAD5U9D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9D8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="716" mass="81274" checksum="4107B18FEF0D3A67" modified="2024-05-29" version="1">MSNATSEEVILPLKEFIKTLDNLNVDNSEETYSISTFFKKVVSFGSGNLDDLGVAAPMTLLEPESGLKMWVKRNVNPFIEIGGDDPIERMISVLKFQVANLAFIAHKMKKPLNPLISETYFSTFKAKNDEIPSVVYIAEQVSHHPPISAIYMSTANGNVQLHSTTFPKFTVGKGMHLLIKEQGSSIINIHSWDEVYEFGIPNIIVQPRATFFYDATVDLYFDGCLTITCKKSNLHVKINFAAKTFLRNPGTGITGEIYYDDDSGPHHDVLYTIGGDWKKLIWLKKVGTKKEIIIADNRKCPRDIGLVLTLPEKLDDSHSERVWSKVIEAMQKKDYKTASKLKKSLEQWQRSYFLYLKKNNLDHHPEYFKKNAVELDSNKSWIFKTEDFELVKDNANLYYKKIEKTSGISESMDGKTTASENTHLTSKSNKSEEFENFKAEEEISYAAHSELKEELSPSTSDIINSRSDAHDEIKAAETSEEFSLVSAVESYTEDFISLQILMILKDERKNHSKSINNSVNLEECQVQVAELFVKNDISDVSLPTEIERKNDCSTIKTIEPCRKLADEEEKFDLVLAFDEANIFVEANSVCSEPKELKSPSEEVVDCNSLQNVRKKEEGESEEVLVFNSTEEVDVEVIKNRKIFSRLENNKEVECRHLSNSSDANESISVKKLLKTFNGENFTLNCETESLMKGEIEAIEGKKVLSKVVRKLYVDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9V9</accession>
    <name>A0AAD5U9V9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIF subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">TFIIF medium subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">TFIIF-beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_004173</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIF beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9V9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005674">
        <property type="term" value="C:transcription factor TFIIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07980">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000035">
        <property type="entry name" value="General transcription factor IIF subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003196">
        <property type="entry name" value="TFIIF_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040450">
        <property type="entry name" value="TFIIF_beta_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040504">
        <property type="entry name" value="TFIIF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011039">
        <property type="entry name" value="TFIIF_interaction"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10445:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02270">
        <property type="entry name" value="TFIIF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17683">
        <property type="entry name" value="TFIIF_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50916">
        <property type="entry name" value="Rap30/74 interaction domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIF beta subunit N-terminal" evidence="12">
        <location>
            <begin position="36"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIF beta subunit HTH" evidence="11">
        <location>
            <begin position="201"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00081473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00081863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3226755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="32258" checksum="F4079CA9996218E7" modified="2024-05-29" version="1">MDLATKVEPKSEPVSELEEKKSVQPKKKIKMDKTEDKVWLVKIPKTLAEKWEAFSDAGHQLATMKHKAAIGEKPEEITLHIPNATWSEDIPKNYQLKVSNKGTKNSYVFTENEQGEAEEIFGTVFHEAQCTPIMDKEYRDFLKKKSKINEVKQKPVRTVKKMDEKEERKILFIGGSLKSQKETTNFSTAKKKIKTQDKNERMDRDDLINILFQLFSEEDYFSFKSLVERTKQPQQFLKEVLNDICILNKRGPYKQEYGLKPEFKSKKVEAEEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAS1</accession>
    <name>A0AAD5UAS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">R3H domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">R3HDM2</name>
        <name evidence="4" type="ORF">HK099_004419</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAS1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02642">
        <property type="entry name" value="R3H_encore_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051937">
        <property type="entry name" value="R3H_domain_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15672">
        <property type="entry name" value="CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15672:SF8">
        <property type="entry name" value="PROTEIN ENCORE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="3">
        <location>
            <begin position="72"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="377"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="511" mass="57968" checksum="ACA935A14F05AD2A" modified="2024-05-29" version="1">MVTEFENELQESIGASETFNIESNSQQLQQQPSLPTCSNDTKPSVPSPSVKLDPETGIDTFLVSTVKNQKDRLFVLKIDVDLEAYALDSHRTKMEFPGMNSYQRLIIHRIAHQYGMAHVVDASRRAVIIYKTNATSVPPLLLRNIPLSEDTKTEKSHGIQESSSKSSFTLSKPLPNGNLKIMQRGHLNHRNNQRQSKMNNYHRDYHGRFLEEKVIACNELRAEIFQDNDNIMSHTFENSDNVERTGSQKLSHVTRKNFGNHSRPRVPSYCGNHTSPAQRPFDTYGNFHPSAIPQYHNNPVRQNNSFMRLPMHPSYFYGSNPLYAGPEVYRNCDSDIEGCQLLPTNSFHHSPIFVPPYADPRYPPFIPFQYYAAPNTSSLSSQSSQNGEYDINTDSGENDGDTTSSPATDILHYEMMPPGYPNYNSDFGDMLPSGYMAPGYSYYPMMYQYPRPPQSYFGYPFPVHHETTSNYINSQGSLSNQDQIDAKIKSNENNNNSLENLIGGVEKLKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB58</accession>
    <name>A0AAD5UB58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cilia- and flagella-associated protein 57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">WDR65_2</name>
        <name evidence="7" type="ORF">HK099_007827</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB58"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000271">
        <property type="entry name" value="cilia- and flagella-associated protein 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052993">
        <property type="entry name" value="CFA-57"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="516"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="EML-like second beta-propeller" evidence="6">
        <location>
            <begin position="524"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="639"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="959"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1089" mass="123538" checksum="F7B0093C5E036832" modified="2024-05-29" version="1">MATRGKKSSYQFRQNLSFQADTPNFLKKLQNAEDEKKVTKPKEEANPNVNDELPSIEIGKSGISETEAKLFLELQHGADPEKRGLKRKELEDFKNLRKDEEIDLKKNQICEIGSNSKIKKAKNAKQPDKNISSKKIKNSNLLSFGDEEEAQVFGLKQDIKDNLYTVDDETILYPAGSNVLITQKGHRKFISVTEKGDSISSLTVSPDRHFLAIGEKGSRPSINVFDITSIRKRRTLYACSETISAKEFISLGFSSDSKYMAAQLCGPEWILHYYAWDKGKLIATINSHSDNPESTVLQVSVNPSDGTVIFVLGDNFVKQYRYTEGELLKIEVDVPKNVSNSIFKTHSWLNGDFVAIGTEDGKVLILNPGGSITQEIQINSTFLSKISLPASNNPSVMNQNICSSTHQMQQNLGASQSNSNFSIESIVVTNTGLIAGSKNGNIVCFDNSTDIETGNRKYIPNKKFLVPDGGVVRTMAIASTEAHLLVELESNQILKIPLIIKQEEQFDEIKFEAISEAFHHGQILGLDLCCRKPLLVTCSNDKSIRLWNYVTGQCELIKYYPEEAYSVSLHPSGLYLLVGFSDKLRFLNVLMDDFRFFKEFSIRGCKECKFSNGGHIFAAVHGNTIQVYSTWTFENICVLKGHNGKVKSLYWSPDDNFIVSAGADGAIYTWNIRDLKRESEYILKTCAFSSAICTPNGKVVYAVGSDKMVKEITESQVTCEFDGGIVATQICLSHSGKMLFVGTANGSIRSIKFPFTSDPDSFQEHFAHSGAITNLRMSFDDQYLFSASEDGCIYSFRVSEKEERGIKRERILLFADEILITKSDLEEKNVLMTEMQSTFNELKLEHEYQLRLKDLSFTDKLKELTETYSQEIEGLKILTSVLRTVKDKEEVKHEEEVMHVKATHGQELHEIESKYNSQLMAEYDKFQEAQTLMAMHQEDWLGQVKEFEFITQKMLQDTQAEYENKLKLKSAEISRLQEEMRQDSNEFAEMIRQNEEDIDIEIANLINKYEKKLRIEKDEGARLKGENGIMRKKFNTLTKDIDDNKSEIEKMRDDEKKLNFVISTLEKEILGLKKEVNSKNTVYFKLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB94</accession>
    <name>A0AAD5UB94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_002175</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="JADGJW010000017">
        <property type="protein sequence ID" value="KAJ3227424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB94"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000008">
        <property type="entry name" value="L-threonine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="entry name" value="Biosynthetic Threonine Deaminase, Domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF11">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="13">
        <location>
            <begin position="60"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="14">
        <location>
            <begin position="361"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3227424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="520" mass="57818" checksum="2A39EE2F27F61A84" modified="2024-05-29" version="1">MEENLKKVKNEKNTDQTLKKNASKTLMSINKDPLFLSTTKLVSIYRNRFKTNKANVYDVAKETPLTVASNLSDKLSRNVFLKREDLQPAFSFKLRGAYNRMQQLNEIEQKNGVIACSAGNHAQGLKATIVMPLETPSLKVKNVIKLGGKVVLFGKDFDEAKQECKRLSLLEGLTIIHPFDDPYVIAGQGTIAPEIFRQHDPKDISAIFVCIGGGGLICGIAAYTKKVFPHIKIIGVEAFDAAGMTSSLEVGKIVNLSTVGLFADGAAVRSVGNLNFLIAKDLIDGTVLVSTDEICAAIKDVFEDTRSIVEPAGALAVAGLKKYIQHLNLNNENLLEVGKNSLVAICSGANMNFDRLKFVAERADLGEDLEVLISVVIPEKPGTFVQLYKAISPRKITEFVYRYENTEKANVILSFKVNQKNVTREEDVETVFRDLNNLGFFARDLSYNEMAKAHARYFGGGRKKVPSERHYRYFGGDTGTICLGIQVLEETRVEFESFIQEFPFHSKEETNNEVYQDFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBQ3</accession>
    <name>A0AAD5UBQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PSA2</name>
        <name evidence="7" type="ORF">HK099_000424</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBQ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="6">
        <location>
            <begin position="282"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="409" mass="46030" checksum="2C6DCA701BCB8237" modified="2024-05-29" version="1">MTLPKPLFPIAGFPMIYHHVAALSKIPGMKEILLIGFFEPKIFESFLNDVKNEYNNINIRYLREYQALGTAGCLFHFRDEILRGNPSKFFVMNADICSSFPLNKMLEFHTAYPGALSTLLSTRVDKKDVHKYGCVVTDPNSPHQVLHFVEKPETFISDLISCGVYLFDSKIFDVIKLVIEEKRLKAVENGQESKEEKVRLEQDIVSYLGTQGQLITFTINPDTDFWNQIKTGSSVIPANRSYLQRFKKHESRRLSVSSPNAKVLEDLLKKQPSTLSQEPQLIQPVIIHPTATIHPGTKIGPNVMIGPNATVCKGTRIKDSIILDSVEISHDSCIINSVVGWGSKIGCWSRVEGSPEDAHHLNATYKGLKIPSATILGKEVNVSDEIVIRNCIVLPHKELKYSYHNEILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRW3</accession>
    <name>A0AAD5XRW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001553">
        <property type="protein sequence ID" value="KAJ3202560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="101" mass="11425" checksum="33E2C742933A22C8" modified="2024-05-29" version="1" fragment="single">MASLSKGNPVNIPELGFGYLYGNVNELGNVSRGPGKSYLFFLTNYHPEIGLSRDRVKCWEKRSNFVVSGALLMILENPRERIIFKPSRTHNRSRSPRLTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS34</accession>
    <name>A0AAD5XS34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex protein EXO70</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">EXOC7</name>
        <name evidence="6" type="ORF">HK099_001384</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Bud</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Bud neck</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the EXO70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001384">
        <property type="protein sequence ID" value="KAJ3203751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS34"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.170">
        <property type="entry name" value="Exocyst complex component Exo70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004140">
        <property type="entry name" value="Exo70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046364">
        <property type="entry name" value="Exo70_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12542:SF41">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12542">
        <property type="entry name" value="EXOCYST COMPLEX PROTEIN EXO70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03081">
        <property type="entry name" value="Exo70_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex subunit Exo70 C-terminal" evidence="5">
        <location>
            <begin position="226"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3203751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="438" mass="50794" checksum="D18D278C5F6CE0BE" modified="2024-05-29" version="1" fragment="single">MKKKELLLKATHQLDEVFKFKLMTACSNETSQDLVIPDQTVQSLQVFTNQLNSSTQLLAECNVDFNKKPLLAGNTSSGNGLAEEQLGHLQPQGPLHIRTYVEIRSHHLLTLCPQLFEKYAPIHNNSVGGYEKGSSTFITYSRNLFKVMKNERELIQKLFLKGQALQAYQQSIVLLVDKYIENTEVLMGKFRRRWSVEKIDSLFHLLDMLECITALIKDHDGLLVGDTSKISLLSVDGTVHEITSKAFNTCRRLLDYNKIIDQILSDNWGAMNGFPMQNFQSFLMEILDNLLINLEQRSKLYSTKLKQPTLGIMFLLNNYQYIHKIFFKEKILADTFGKDAIDNVEKLLKAQRDAYLNSWKPLYDHLFDNTYVKSGQLAKTLNKSEREVVKEKFKGFNADFEEFYRQQKNWAVPDQDLRNYLLKEIKAVLLVLYQRFYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSU6</accession>
    <name>A0AAD5XSU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000237</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001043">
        <property type="protein sequence ID" value="KAJ3207626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3207626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1434" mass="164535" checksum="001D14025AD3F624" modified="2024-05-29" version="1">MSGIKNDFSCEKGFLKNKNRKTDIETKNTSKNEGVSRKKIHKKSLATRVMDNFNSDIITGNRLTLKHDRGKIGIFNNGKKSCSFNASGNLSSIAFNEKKFFSDGEIDEKNSWEKKKIKTQKIPTRSSYFMEANKESLTRATDQVEHKKKLNSSISSKKSHSVASTLEISSQSDDSLNKPVNISIKRINKKVSPEQIEDAHKNALKIAIPPINSKRKKKEEVTDACDSVKKSKIMDSTFSQKKLETQLGELNSMGAREELDCDNSVVANVVESQFEFKNIDNSVEKLESEGGRNANFSSPLIFAQKSEINSELEQITNKQENFNSTYDTEEQKINNLLDKEIIKFTELSELNNEVEDFDQFNDEEFWELVIQQHKNDVERKSFLTNVNNDASQYSLNEPMNNSQNLQNNASVGNETMNQDTLMIPSDILSGEYQNTFQCNNTKPYIPNNISEENQLIHRQHLLPNSSCVKNFSYNFPLEDVDESITSGEFLSPHIGVDARVIVAKDEDLRFKNRSSNIDTDTNNFVSILELIMDFQDLYNSSQSLTSHIVSTNFPSIDRGIDQIEQQSRKLFSKTTREGSRNIDTRTAYLLANKGYDAEKVAETLEQIDFAGTFESLNPIQDTDVESYLQHQHEIIVLSAVEDGRKQCVDDFEINFEKNLTRDWEISRKRIFEELGQRKALKRASPRTSHEFFRQSRHQYTYLPKTTLNPKMKNFSKVVMSLNDARLKEEDFGLIASFTKVVKQNEKGGDVTEKQLSDCWKLLSNILMEKNVENGVFKRNSLSALHYKELFDSQIQDNKFTVNNFQKIIVEGGKEFLSQHFWQFMEDSISHNRSATLGMPSVNTVVDAFVKLKFTKYGNFTKSYIEVYDIGDSKKAIWVHLFYLVRANRTNEAVSYIEEHHSYFSSSDSNFSNYFKTWVSGGLDKQLRNMLLQHWNNYIKDSLKVGNRGIIEGDPFKYALYKLIGRCELNRKVVPGNDVLPSTQDYLWFQLMLIQEGTKSEESTQDRFTLRDMAKSMKRFGCEHFCPHGKQLTNWAFVLFICGEFEQAIDFLFSIPDLQVDAVHFGIALAYYGVLRIFESPHLGNAGIKVLDYKTISTPAGEYQISSINFSNILESYSKSFSTSSTVEALHYVFVIGLFGSEIEDVDSQFFSNQKKPGAQEYTNILHQFIVDIILENLDKIDLLLGSVRDDCVRLPGFLEKYMKLLHIKSTEAFLNIITKTAATKCDERGNYDDTIVLYDLAGEYDEVFSILNKRLGEKISQRTYVGPLQPAPVSFKLQDQKISLIATEILDKYENHAQIFNKVKRSKLDGCKILISLMEFFNLIDQKKYKESITITDTLKIFPTIEDPKLAKKKALDLEILDENVLKVLDGVLIFLMYSYRQLNNSFKRFGNFEELHEINTRMKALILFCSNVRYKLPQDVYGQLVKLHNGEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT29</accession>
    <name>A0AAD5XT29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">DBP10</name>
        <name evidence="17" type="ORF">HK099_008475</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000932">
        <property type="protein sequence ID" value="KAJ3209593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT29"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17959">
        <property type="entry name" value="DEADc_DDX54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000865">
        <property type="entry name" value="ATP-dependent RNA helicase DDX54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012541">
        <property type="entry name" value="DBP10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033517">
        <property type="entry name" value="DDX54/DBP10_DEAD-box_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF8">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08147">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01123">
        <property type="entry name" value="DBP10CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="16">
        <location>
            <begin position="142"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="173"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="379"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="921"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="142"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="921"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="946"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="978"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3209593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="987" mass="111687" checksum="FB845C1702C140C2" modified="2024-05-29" version="1" fragment="single">MKIKNSKLKGKSSISNTTKKNFKNNLNRTDFKSSLPKVKRNNKLNDAKGQFKKKKLRNNNFPEKNSKQENTEEDYSGEEFEADDDFETVPQVEKIVNFDDLSDKETFSDDEVDEVVEKKIQKELKDMKLKIQQVNKKAAKQGGFQSMGLCAPLFKAIQHKGYKIPTPIQRKSIPVIMEGGDVVAMARTGSGKTAAFLIPLIERLKSHSAKVGCRGLVLSPSRELALQTLKFVKELSKYTDLRAVMLVGGESIEEQFNAIAGNPDIIIATPGRMMHLTVEMNLNLKTVEYIVFDEADRLFELGFAEHLREILFKLPENRQTLLFSATLPKTLVEFARAGLNDPALIRLDTDQKISKDLQMVFLSIKHEEKDSALIYTLSNLVGNGEQLVMIFAPTRHHVDYLHELLKAAGIENTYIYGALDQSARKIHLAKFRAGKVKIMIVTDVAARGIDIPLLDYVINYEFPGSPKVFIHRVGRVARAGRSGTAISFVSSEELPYLLDLQLFLGRPLILGSVYENQEKNYEKNKDIIYEPDYTSEVIFGTVPPGVLGMDMEVVRGIIESNATVKAMQEASLNGFKLYLKTRIAASAESYTRAKEILSSYIGMHPIIVEKSGKEEVEKQNMLRNLSLFRPAETIFEVGKRGNKAKEAVMMNKRRKLLTELITSSNVLRVENETEMKKKQLGAIKNRLGIALDNNNNNEEESIIQDKLIELAEEKDILDAFPNSKKRKLDFGDTDFKDTEFYMSHYQKDEFSERGYSMKSKPMTFAEQVKSATMDLNGDDQASMLRGKNAKKGLLWDKSKHKFVRPTVGSDNKKMIKTESGALINASYKSDRFEDWQKKKRIVLPRAGENELSDAKNYQRGFQEKRYRYNTFTAPTENSKSSIRKQFKRKGQELASGISASKNTEELVKYKKGNKLKLVKHKTEGLKTNSKQELKNSEQIIRERKEKDRRRAKTGRHAPGHHAARGKSSIYKSGGSGKSKGKFGKSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTK8</accession>
    <name>A0AAD5XTK8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Selenoprotein O</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007676</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000766">
        <property type="protein sequence ID" value="KAJ3212711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTK8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070733">
        <property type="term" value="F:AMPylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057:SF14">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3212711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="492" mass="56235" checksum="FC88AF128993AE2E" modified="2024-05-29" version="1">MFNLNFTSKLTSTLIPDAATPTTANNFSILQRMVKDAHFSYVKCETFPNPKLISVSENCLKEILGCNERTIENIKADSKTKEEFVKYFTGEIPLYEKQNPWALAYAGHQFGSYAGQLGDGRAISLAQFYDPNGKIQELQLKGAGLTPYSRFADGYAVLRSSIREYLCSEAMYHLNIPTSRALCLIGTDKIVYRETPETGAVVCRVAPSWIRFGSFELPFYRKEVKLLKILADYTIENFFSKLANHEKKYEPDYICNHSDEAGVYSFENQPNAAYFNMAKFATALVPLVLEEEGNDKQKTGNVLTEILQSFVNEMKEKHLLEMHKKLGFSTKTEESMELVKLLLVALPPAKVDYTIFFRELSEFKTKCNTDEELVLPPTIFIEKAKESNVGSSKDNLKLLKDWFKSYNNYLIKENMNDEARHLRMKSVNPKYILRNNLVQDCITLAEKGNYSLLEKYFKVLQKPFDEGTAEDYQLFGGLVPNEKRRIRCSCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTS1</accession>
    <name>A0AAD5XTS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000689">
        <property type="protein sequence ID" value="KAJ3213665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTS1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="510"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3213665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="65249" checksum="A97E21E718F2B7ED" modified="2024-05-29" version="1">MNYTSNSKIFLTASDILVKSSKYVNVTNVITFFLSLGTISFLYLHFKLRRNVRLFKKLTNNEIPVKTQYFDFLAYPVLNAMIPEFLRGSKKNWKYQENCYEPYANTKHETICLVTPFSFFLDTANPSFIKQVTSNSVDFPKPVHIYQAINVYGPNIVGTEGSEYKRHRKIAAPQFSESNNMLVHKVTNDTLLQMFASWEKTVDANSESRVKVSHNMSKLTLSVFSAAGFGKVLDWEKFEELIPKNHTTSYSTAVTNVAKNLILFVITPKFLLKSWIPLFKSVKENLDEFSLYMKDLIQEANFTLKSEKIRDSESKKNDNNLLKRFVAASEQIDLNSGEEAYKDKYMSVDELKKATPLTEAELVSDLFVLVFAGFDTTAGTLNATFTILAEHPDIQENIHKEATALFGNGLPSYDLLSSLHYTNAVIHEILRMYPPVAEIPKWSTKEQPLGPVTIPENTIITIHTMALQRSPKLWENPEKFNPARFLNEDGTFNNKMENTLTVFSKGQRACLGKQFAKVEMLFTLALISQRYTWRLPDDLDKNINIKEISQELTHKFKHTVDLMFKKRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTV2</accession>
    <name>A0AAD5XTV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA-ATPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000665">
        <property type="protein sequence ID" value="KAJ3213918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTV2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018631">
        <property type="entry name" value="AAA-ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012547">
        <property type="entry name" value="PDDEXK_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825:SF1">
        <property type="entry name" value="AAA-ATPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825">
        <property type="entry name" value="CONSERVED PROTEIN, WITH A WEAK D-GALACTARATE DEHYDRATASE/ALTRONATE HYDROLASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09820">
        <property type="entry name" value="AAA-ATPase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08011">
        <property type="entry name" value="PDDEXK_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA-ATPase-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="530" mass="61395" checksum="10A1449965F96F2A" modified="2024-05-29" version="1" fragment="single">MSVVGEEFIIGTSDFDEIIEKNALFVDKTLLIKEFIEGSAEVVNILRPHRFGKSTNLSMLRSFLSIGSDPNRFQRYLIFKEEKFMDQHCGKYPVVFLDLKDIKGDNWDEMLCKISLYVGKLVNTFSTVLNSKRSHSDQLDFDAFTSLTADKGLLTTSLSFLIKQLCKIYQRRVIVLIDEYDSPLNNAFQKGFYDNASSFFTTFFSSALKGNSALEKACLVGVVGIGSGPDLTGLNNVVFYNIAREKYSTFFGFTTEEIRFFISDEKTLDEVLNWYSGYWIGSKQLLNPWSFLLWLKKKEFKSHWVEMANIENLFTFLHGHKQLFIEILHIVFSGDPLDVSGLRSVVDYSKNAWGRKDGILHFLVHAGYLTYRKGVNQRGEVFIPNNELHLLWKVDIFPFIKKEMNSEFILPLQKAFTAKTFCATALQNLMRNLVEYPSFQNTTSEINYQKFFYCLFLGVLQDKESVQVESNKENGYDIKLDFLNLKRIFIFEFKKSENEASLEREAKKALEQIIEKEHYHSFTNRECILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU80</accession>
    <name>A0AAD5XU80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Meiotic recombination protein W68</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MEI-W68</name>
        <name evidence="2" type="ORF">HK099_006616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000584">
        <property type="protein sequence ID" value="KAJ3214898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU80"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF0">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="1">
        <location>
            <begin position="76"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="1">
        <location>
            <begin position="369"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="484" mass="56589" checksum="B46BAD3A6B21777A" modified="2024-05-29" version="1" fragment="single">MENLLLDNINKILDQIANKVKEAEENFVAASKGMVAGCLKLFLKDGSIIDCENCGTQGIVIPPMSQVERFETCANFVLVVEKEATFRSFVADQWWKETFEHKNQIYSRKCILITGKGYPDVASRVLLNKLSKLTTNNANESRFFSFDEEDNSLNTNDVNKIVHSVEQSEFFFNNDFDPEDLKNHENEEMNFYENEEIHKVFDNNPSKQNNYLNSLMETALLNNPEEILFKNEHLIKPSNGSEQLVPLFNENWEREFIVEDCDELMFDFENEDTNVEEINDFEMNFENNFEMENFSSPKIQHNILKRESLNLFNQPENHLNRSSVEIPTAFVEEDFDFNNEFENEVEILNNDMSYFKNEYDNWNEDVNLLPCYCLADGDPHGIDIVLTYKFGSQAMAHDALNLCCKNLIWLGISYDDIKLKLHQERRSENFLLNENSFSKNLIKLSDTDIKKCFQMLAKLKENKFWRAQISKILHFGYKAEIQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUA2</accession>
    <name>A0AAD5XUA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Histone methyltransferase set2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SET2</name>
        <name evidence="11" type="ORF">HK099_006503</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000566">
        <property type="protein sequence ID" value="KAJ3215126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUA2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046975">
        <property type="term" value="F:histone H3K36 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19172">
        <property type="entry name" value="SET_SETD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044437">
        <property type="entry name" value="SETD2/Set2_SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042294">
        <property type="entry name" value="SETD2_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46711">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46711:SF1">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17907">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00570">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51215">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AWS" evidence="10">
        <location>
            <begin position="116"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="8">
        <location>
            <begin position="173"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="9">
        <location>
            <begin position="297"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3215126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="417" mass="47301" checksum="3F127983B5F1B56F" modified="2024-05-29" version="1" fragment="single">MMEVLLDTTAFNEISIKKETCLHIKVASSNNSNNSDSTLDTTISPCDIERKDDIVDTPFDDALNSPTEEICSQPVLNEEIFNKKIEISPVYAEALTTFTPIQENEYKRGASGKLPKDFMPCCCKFDEGKDDAGLACGEESDCINRALLIECTDDDCPLRSACQNRRFQNKEYAPIEVIKTEKKGYGIRAMENLRSNEFVIEYCGEVIPQSNFVKRTKEYSKSGVKHFYFMSLNGDDLIDAQKKGNISRFLNHSCAPNCMIQKWVVNSRMRMGIFTLRKIAAGEELTFDYKFDRYGKEAQPCYCGEPNCNGFIGGGNKTADSDDDEEEDVVEMDAKKPKRPKKEAKVKALENIEHVKTLVKKMLYSTKLPSQVTKLLRRLEVTDNLAMRKCFVKFHGLLVLKSCLTLYSRTDLSLCYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUE0</accession>
    <name>A0AAD5XUE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000528">
        <property type="protein sequence ID" value="KAJ3215661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUE0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="44209" checksum="0AE636EDAC4DAFDE" modified="2024-05-29" version="1">MTGHLTKKNQLQAYKRVPPKIPEKVIVGYANWHQCDEKILEAVENGVNVLMWFSIDLTADSITGKPLISRGPDLGCVAHMVQRIRKLNLITIHFIAIGGWNSVHPDTRNDASTIYAEFDRWNREDVANPELEWYGFDGFDWDLEGNDDILHPNNEFTLEVLNVMGEMSVLGKKDGYLVSMAPCESYLDFSTSNFSRSARLTNPEWQQLHPEFTYHSANVYSYVLVKFGLENFDFVFLQFYETFSHLLYKVLIENIKPADALIKAIEDITTGWFVDFTTDDLTKDLSKVQLKIPFEKLIVGLGNFNYKSERSLYIPSEDCRFTYEHFLRLNGKSIRGFGFWDIADEGNILYKEKKLYLATELNKFLKIRTVREEERNVFDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUU9</accession>
    <name>A0AAD5XUU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000439">
        <property type="protein sequence ID" value="KAJ3217182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUU9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="491" mass="56353" checksum="74D002C7CEA07F2B" modified="2024-05-29" version="1">MKEGRIFRGDYKSSLETLDTHIVLISIWECLVTENSKITLFETMYLNDEILFELLSLVGYKDCRHYDKDLLNQVTKDLKDHFKKLNIDQNTLQEFVEASSSSSSKEKKGKSRKMKVHEKRKLSTADSSKINSSNTNVLGNNDVSTILKREEAAFEGYKVSHKDSTSRKLKNSTFFELDTKKHVNEVYEQELRSSKSTASNSLKISDDLRRDFDMTKKNLNEIIDLNDLYKKIEKQKKNGYDINKNVKKDDVYVGSSASDVNGDKFIEDNELNSILYVADDEKEEIESEIDYHSGDMLCRDNGNDLSTFTSSTSTNLLTEISDDDVDVAELNEEDSYLSSSSRESFKPKNNSSLNSLSKTSTECPFHTNQFASVIKCSNNPTNKRKKIDPVTRYHKFNNVWKNDNFLKRNEDMQQKFCKIKNLSFHSGGGSSKYLSGKGNFKPAFGFQKGENGPKLPRHNYSSMRIDYVVPTSKLRKDLVWETRNRMAKVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUW1</accession>
    <name>A0AAD5XUW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001537">
        <property type="protein sequence ID" value="KAJ3202659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUW1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="74" mass="8482" checksum="8824B0204662F6F4" modified="2024-05-29" version="1" fragment="single">RELPKTVYNNVDTENIKVTKQNNSNWDSWDLQLYGAALRDDSVFLLEANEEQPVKSSATQVEINKLGKEKQTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVB6</accession>
    <name>A0AAD5XVB6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_004843</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000356">
        <property type="protein sequence ID" value="KAJ3218994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVB6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF31">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="21"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="117"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="228"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3218994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="303" mass="33633" checksum="8814DF1B3D951B7B" modified="2024-05-29" version="1" fragment="single">MTFQTAHHSTTFSFHNLLKKDSTSADLIFGSIGGFGGRLIEHPFDTVKVRLQTTNDFLNARDCFKKTFQSQGINGFYKGLSSPLYGSIFENAVIFASYTFFQNQINNFYNQPKESDLTLKQLCLAGALSGATISFIMTPVELIKCNLQVQDLAKVNQGKLKYSGPMGVIFSTIKYKGFTGLFQGQVGTLMREAVGNAAWFGAYETACTGFIKRKQSLTNNLNFSKKNLSNIELMTAGALAGMSYQAAFFPADVVKSRQQTQEVLTGLNRNFWDITKDLYKEQGIRGFFRGFNLTILRSAPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVV0</accession>
    <name>A0AAD5XVV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Low temperature viability protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001526">
        <property type="protein sequence ID" value="KAJ3202749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVV0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007307">
        <property type="entry name" value="Ltv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531">
        <property type="entry name" value="LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531:SF0">
        <property type="entry name" value="PROTEIN LTV1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04180">
        <property type="entry name" value="LTV"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="469"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="64144" checksum="4C13F29FD64A49EA" modified="2024-05-29" version="1">MAKKKFIDKNKSSTFQVVHRSQRDPRIADETASKLVLKPVLPSKNLVRKGNYDQQSNFVPDEHFDDGVFEDQTDSDEEYYSDINSQQDEDLETIDVNKMNKKDDPSLHGIFFKDNEEYDYLKHLKYMGDDPSAVFMEKKNVAKPTILKTGIQFVDEDAKNSMEESTSTQTSRKVKFNLSDEVFASNNEEEIGMLNRGSGIISGFGLDLDHDTRQTLIALEDEAFIDENLDEDFFAALDGDVLPDDYVEEELNVIEDEEDWMKEYRKFSKAEVPDEQYINSDSDEDFKDYEEEREEIKSTTSKARSARSKKSGTTNFSMTSSAIFRNSNLTLLDDRFDRLLDAEYGSDEDDDFDSRDFESLMNDDIVKSGAEIGGRNLEKIFDDFLELDLKGKRLIPKLTPLGQIEEIRETLKDVLPKDLEKYELDRANEVEEEIPMPIEKQRDNWDCETVLRAMAAFKEMRREKLFGKKEVESTSDQENLEEEDEIAVNKGERRPKNETKEEKKLRKEAIKNERKNRRLQKKDTQSQFKQETEKQGKQLKQLKENKKLHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWJ0</accession>
    <name>A0AAD5XWJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_007185</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000676">
        <property type="protein sequence ID" value="KAJ3213795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWJ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF3">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="8">
        <location>
            <begin position="114"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3213795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="353" mass="39269" checksum="0C0410A4D2136352" modified="2024-05-29" version="1">MISFLDSSNWFAFGLGSEMNSAELAQPSKNQVLLSRRAAIGHDLPNKVKNQDFQVTESFSNETYSFVVFTRPKVASSAQGVERKLISGETPLIWAVGLVENGNIGFHTDFNIAAANLFSPKSAFNGQLPPPPMDNSSEERNNKRFLLMKIHGWVLFVAWGILAPLGIGVARYSKDYIPERWFNIHVSVLFGGSFILTIVGFILVFIAVDVGGYTHLDYTNFDFSGGVHILLGIGIVVLTFLQVISGFVIDKLFDANRTEIPWWDKAHHWVGRLLVTGSVINIPLGILLFDLVSHSINSVWLALYGGFIFSVLVTFGFLQYKIGGTEHKKLETSESQESLVESYGTFHENEETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWP7</accession>
    <name>A0AAD5XWP7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001015">
        <property type="protein sequence ID" value="KAJ3208062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWP7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Apple" evidence="1">
        <location>
            <begin position="5"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="81"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="116" mass="12053" checksum="2CE67CA7D675AC92" modified="2024-05-29" version="1" fragment="single">MPDSGDKCGSACAGEDQCSHFTWNAGTCFLKNGGSNQGNAVNSGVNSVCGWKDGNNGNNGNNGNNNGPINWNGNNWALGCDFPGHDFKQVSMPDSGDKCGSVCAGEDQCSHFTWNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWX2</accession>
    <name>A0AAD5XWX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Striatin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001985</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat striatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000162">
        <property type="protein sequence ID" value="KAJ3222719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWX2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013258">
        <property type="entry name" value="Striatin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051488">
        <property type="entry name" value="WD_repeat_striatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653:SF0">
        <property type="entry name" value="CONNECTOR OF KINASE TO AP-1, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15653">
        <property type="entry name" value="STRIATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08232">
        <property type="entry name" value="Striatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Striatin N-terminal" evidence="8">
        <location>
            <begin position="13"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="281"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="331"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="473"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="25"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="558" mass="63877" checksum="C91B6653F7A61005" modified="2024-05-29" version="1">MEVIDQNSNNEINLQSCLLYLQKEHRRYEMDRNEWEIEKATLKNRVAFLEGEKLAAENIKQDLLRRIKMLEYSLIKLKEDNDDKSPIHNQTAKDIKKKNRESGNSILSVESSNLLNFSKGFGHMRSTELLKSYLKQVGYLMLNEQNDQPLLDPNENILPKVLLQKKNSNLNTTNKETETVPGSVQNINNIPENNQISDELRNLSITSKDKEQDSDLNNDKLLWKPVATLKSHFDSIRHFEFSSTENTLITASEDHTAKLFNLSNVKKHYQATNEIDPVFTFRGHTGPLTSMQYTRNELYTSSVDSTIRCWKVPDKNQDKYESFDSGLTRTLVGHTDIVWSIKLNKNQNLLASSSADSTVKIWDINSYTLKQTLKNTDCNENLSTFRPTVVDFFDNENKIFIGTREGTISLIDIEYGKVLLKFENVNSVNEKNDTYFENQVNCLDFKNGLLISGTENHKLNVFDINSGNLITEVLAHSNSISTINFSFLEENVVASGDHDCSIRWWDIKNLSSINCLQEITTHRKKNDSGVFCCRYSKFNNGLFGSAGADGLVKLYLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX01</accession>
    <name>A0AAD5XX01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">tRNA methyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TRMT2A</name>
        <name evidence="6" type="ORF">HK099_001780</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000154">
        <property type="protein sequence ID" value="KAJ3222895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX01"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045850">
        <property type="entry name" value="TRM2_met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45904">
        <property type="entry name" value="TRNA (URACIL-5-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45904:SF2">
        <property type="entry name" value="TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="444"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="575"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="547"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="625" mass="71261" checksum="07A7B0BB08DC9280" modified="2024-05-29" version="1">MEDTKNGIIVDNTNVSNVNSSSELENLAERENKRIKLAEAADEEVSNDENNLTYKLKITNLNYKSTAKTFKKHLASQKCVDNIKIKKAPKWNHAILTFDNIDDLNDTKSKLEGTKVKDLEIHCTEVIEKLHNSRVQHDKINVIPIEESKKSPEDIAKLLNNQVTPLWEKPYDQQIVIIEREVRKVLAAFRKRLNESRKNKDLTQAQQEMVNWIDDPKYNDFGLLPCIRSPEINNYRTKCEFSFGKDSSGIKNLGFLMGLYKNGCTEVVSIETTVNVSEAAKKLVFHIQDYVRKNALDVYDRVQNVGFWRSCQIRTHSNGEVLAVIQINPNDLSAEKIEEEKQNIKNFLLEKKKENLIELKTLLFQNSNDLFNGITDKDTFEISFGDGTISETLLDTKFKISPNSFFQINTKVAELLYSSLRELCKEFKNEKNLEGNLKSELPVVLLDLCCGTGTIGQILSPEVDSVIGVDIIEDAINDARNNASINSKLTFISCLSSRIIFRFEKCRIHYWKSGGFDKKYISVIQKHVYQGAKESGGKKKRAIAILDPPRAGSHPNVIKSVREFSAIETVIFVSCDANLAKDNFFDLCRPTTGKFHGTPFKLIRVQAFDMFPHTKNFELVLVFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXK2</accession>
    <name>A0AAD5XXK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Plasma membrane ATPase</fullName>
            <ecNumber evidence="13">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_000331</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010001071">
        <property type="protein sequence ID" value="KAJ3207223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXK2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000042">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000211">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="664"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="693"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="727"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="799"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="825"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="14">
        <location>
            <begin position="16"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3207223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="930" mass="101498" checksum="A95628374785AE5F" modified="2024-05-29" version="1" fragment="single">IKKEKAKINEADVPQDDHHVEVTEALDAELEKLLLTPPNTGLTTAQVEERLLQFGKNEIPENKTNPWLKFLSYFLGAISFLLEFAAVITAILQSWADFIILVSVLIINACIGFFEEARAESALDALKNTLALKSRTWRNGELIEVDSALLVPGDIIAIRLGDIIPADCRLLGIGVTGEETEGALQIDQAALTGESLPVSKKKGDTAYSSSICKQGQMLAVVVKTGVNTYIGRAANLISITNEQGHFQIIINRIGNFLVLITVVMALVILFVSIFAQKMTFLHALEQVVVLTIAAIPVGLPTVMSVTMAVGASQLAKKKVIVKRLTAIEELASVSILCSDKTGTLTENKLSFDEPYLANKGSTPSDIIGTGERYTAEDILLDAYFSSEPGAQDPIESAIRKAAESGVALLRDRPAGSAHNIPGYKVDSFTPFNPNSKYTEAKVTDLSTGKKFRVIKGAPQVIVRLCGGHSEATAAVVELAKRGLRALGVARTVDENMEEFELVGMVSLLDPPRPDSGETIRRCMALGVAVKMITGDQAIIAKEVAYRLGMQRTILDATSLTDPSLDVEQLTERCVKADGFAQVIPEHKYRVVELLQDKGLLVAMTGDGVNDAPALKKADVGIAVEGCTDAARSAADIVLLDSGLSTIVDGIETSRAIFQRMRSYALYRIASTIHFLLFFFFSILIFQFTLPNKLILLIAVLNDAATLVISIDNARINKRPDKWRLGQLISLSFVLGVLLCIISYAHFFVAKDIFNLPVNSKHDTRLHTIMYLQISSCPHFVIFSTRLSDPFYKNMPSIPFIVAIAGTQVFAMFMSIYGFPAFDAQAIGWGWGLAVMGISTVSFMLLDVVKVLVIKNWSFEVTAKLWPVKSRRSELSRRKGQALIDSRVRSNIKKVRAASKTILAVSAFQDKTEKKLEPSTSTDNVDTVIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXM7</accession>
    <name>A0AAD5XXM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000091">
        <property type="protein sequence ID" value="KAJ3224496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="621"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1621"/>
            <end position="1702"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="696"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="862"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1122"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="230"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="667"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="679"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1627"/>
            <end position="1650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1670"/>
            <end position="1685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1730" mass="198157" checksum="0925FDC069DD9E84" modified="2024-05-29" version="1">MEEITEFEADLEKERLLKVARKKSSEIDLPESTAISDQPASIADSVDDLEFENRVQNPTKVDTTNKKPPRTLVQGFFTAFNSIINESENLPNTLKERILMTTGGDLPPPKKTPESGFPGQNDSQCENSMLSQTYSSNDYPLSEQINNDSSNVFTNIEQSDNYLPESTVEEHNDFVEQYHVPTISGFSDNNNIVPNFSSNSTNITSKSRLSKFGPSVLNVDSNIYALNTNYERPSSPPRNINANPKNFPNSELANSSLISPPSDFGDCGSVSKRGQTPPLSNSLFSNPEKPSSLDFFNSATLNEGMQNVIFDNDKKTSYWESESRGRSPTQRMPINDTKTSKSPSPKKTGASNNLEARDTYLGNYNYPETGNLNAASRSQSPKINSISVSNTYDALTQEKKVNNISHLISHRSKSNSPETSNSPGSFNFPQENNSIKKDDVNISDQSDLAENKLNNNSEAFPTTTKAANDLLDFNESSDDTVQMNGKDNIFQNVSSTLSNSVETSYTATTLNAMEFKKYTPVATNYPFKTSPAINLNPTETSNIGNKNAGNDQIKTAASLFGSFSSSPQNFSHQLNANVNNFFQPTIPKNQNINAVSTEVKTVTNSQPKKSTASLEICTSETSFKPKPASPPLTLPLKTPLSPDRSNVSSISKLEIDTVHNSKTSYQSSPKTPLSPLKSRNSPTSPSRQLNSESSQVASLQSKIQVLETMLEQTQNNLKSLKKERDDLKFSLENEYEEKLKMLDLRESDVATGELNVKDSLQLYKKIESSANGIEKILEIKRGELEEEYRIKYERLEERESLFFKKSSIFEEELKKVEIEKNNFQNNKLKFHKEFEEFIIEKDNFFKLKEGNESDGYKKLRFFEEEESRLKDYESKINNFYEEVNLKDFKLKKTLEEVDKKQVVLEKERTEIEKLRLESVALKKAVELESKEFQNRLTLLEEQENLFKKNQSKFEKDCKSKEDSFEKKNANLMEEITMLEEVREKTLNDRNLVENEKKELHSRESALKKLSSELEENKELLNKEKAELQKNSLKLEEDFKNFKLHYDNFLKERDSFQDERNRILELQKSLLDEAKVYKDLKASFEKDKAILLEKESASQRISQQLIDDKSSEAAKLSSFQKKLDQEKRLIEFQRISLNEKEEKQKEMLKNIEAKELEVKEEQHKMVKVHENLQITSENLNKKESHLKNLMQEYESKNSKLNKILNDNSKLKIELEKEKLSLNTRENQLKDEKLKIENEKNSILNSLKQTQKLVGEKFQTLEEEKERINLVKENLEQDKKKLKFEQDELQLSKLELENQSCKLNEQFTWIEKEKGAINELRMKLDQDRIDFERSKLESGGKIAKKKAEKVTGEADSVSSILEEINAESIFKSSANTKPASSPSSSINKGDALVNRNYETELNYFKERIMNLESSNRIFQEKIVTLNDKLASQKAEENITKNITPTSEEEKIKKLLEDFNNDEAAKDESTETDKLLKVILALTSKNQTLNKKVEHLQAYENPRQLSSHNSYSSLPYSPVESSAQSNWKFESEQRHRRVYQNNLKIKAAQEEYDSSQRYDRPLSRLSLSERRLEDSRKSLSNSNTDYKLMSPKVRENFGNIAQPTSLSQRRIDLEKRNSKVLSGFDYRTMNRNQESSSSLYSQNQNSSNYNQQQPEMERRNSFTSQHSIRSEYNPRNNYTGSRYSTSGNTKKRLSRGESIVSTGNSENLKNFFDQNDVDAFSETTKKILFGDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXM9</accession>
    <name>A0AAD5XXM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000415">
        <property type="protein sequence ID" value="KAJ3217685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXM9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="236" mass="26751" checksum="3237810A8BCB6AE9" modified="2024-05-29" version="1">MVAKNTFTKVTKILRSTSCEANFEPGLYNIVVKIKYEPNGSPSIKEILQDTSAKDIRKFTSTASSFEFSRSKASNYIPFNIVGVGRNMIENKGLHLEKSKIVKGRKSGNVTLPYNSKKTNSTDNSPTSKQPTDKEEVKELAEEEYGDELAYDDEEELIEELFGKPTVVIGLRVYSKDKNMELTGLYNEECEDFEVLEHANVPDAEEIHLFGLFMSKEPKEKNLEFIPDKVDNLEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXW5</accession>
    <name>A0AAD5XXW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_006947</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000635">
        <property type="protein sequence ID" value="KAJ3214273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="117"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="228"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3214273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="322" mass="35039" checksum="4AD39C8A0A064C64" modified="2024-05-29" version="1">MSLNKTLNDSIPQNTSIIKEITCGGCANAVSTTILNVFDVTKVRLQIQHARGGELMYESISQAIKKIYVEEGFKGLTLPGLPASIIRELTYSGLRFGLYTPLKNAISNLISTETKETPFIVKFFSGMLTGIIGSSLANPTDLVKIRMQAEAGLLKNGVFVTGLNKGLIPSYNNTLHCFYKIWKEEGGSRALYKGVSATALRAGCVSGGQLASYDHTKSTMKKYGIFKEGVGLHVFASVVAGLVATTLAAPADLIKTRLLGQRCDSSIKYNGIFDCAVKTVTLEGPFGLFRGWLPSYFRIAPHFIITLPLFEFFRKLMGLNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXW6</accession>
    <name>A0AAD5XXW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="3">4.1.99.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MOCS1</name>
        <name evidence="15" type="ORF">HK099_007547</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000074">
        <property type="protein sequence ID" value="KAJ3224999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXW6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21117">
        <property type="entry name" value="Twitch_MoaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040064">
        <property type="entry name" value="MoaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="MoaA_twitch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050105">
        <property type="entry name" value="MoCo_biosynth_MoaA/MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960:SF0">
        <property type="entry name" value="MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22960">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01383">
        <property type="entry name" value="cyclic_pyranopterin_phosphate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01386">
        <property type="entry name" value="main_SPASM_domain-containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01067">
        <property type="entry name" value="SPASM/twitch_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="14">
        <location>
            <begin position="58"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3224999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="385" mass="43876" checksum="7E102758E5356388" modified="2024-05-29" version="1">MQKVNKKLFILKRYSSYLINEDVSSSSKIQRIKSNARVKIATIENSNPNLKKEFLTDNFNRKHNYLRISLTEKCNLRCTYCMPEEGVPLSPNGALLTKNEILKLASIFVKQGVTKIRLTGGEPTVRKDLFDIIAGLNDLKLIGLESIGITTNGIALERKLPKLKELGLDNINISLDTLDKFKFELLTRRKGFEMVLRNIDKSLELGFNQVKINTVIINKLNNEDVEKFIYLTKEKKVYVRFIEYMPFDGNKWNTEKFISYKDLLTEIKKTFPDVVKMGDDPNDTSKAYMVPGFQGKFGFITSMSEHFCGTCNRLRILADGNMKVCLFGNTEVNLRDMIRNGATDLELLDVISAAGKIFQISCINLINIVPLTYSWKKKEAACGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXX3</accession>
    <name>A0AAD5XXX3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pre-mRNA-processing protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRP45</name>
        <name evidence="6" type="ORF">HK099_007988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SNW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000083">
        <property type="protein sequence ID" value="KAJ3224739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXX3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="5">
        <location>
            <begin position="174"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="324"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="366"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="602" mass="67531" checksum="6C625C0642CE5183" modified="2024-05-29" version="1">MKNILPKPKAIQSKWEESDSDDQTTKISLKNKIPPYLKRKNYKPVAIEDYGDGGAFPELKFAQYPLDMGRKTAKSNAIPLQTDENGEVRYDLLLNQKQNKDKVIHSSLHDFKEKDLSDEIYERPDDDLINETSEKTRLALEKIVDGNHFLVNYLAKIKANNPKQQNKGQVAGPTYVRYTPQIQNTSSQANSRIIKMVSAPVDPMEPARFGHKKIPRQAPSPPPPVLHSPPRKVTAEEQKNWVIPPCISNWKNAKGYTIPLDKRLAADGRGVQEITINDNFAKLSEALFVADRHAREEVKIRAEMQAKLFAKEKKDKEEKLRVLAQRAREERSGISSTVKEKEEKSDEESGDSSDSDESSDEEVLDENQKKLLKERDELRREKEKQRQREIRLSHMGSETKAKVLGRSGDRDISEKIALGVAQPTMSKEGMYDQRLFNQSSGIGSGFGDDDSYNVYDKPLFSGATAASIYRPKTTAHEGYGQTGIREGDFDKLLGESNKPHKGFSGTDGEAVARDGPVQFEKEVEVDPFGLDQFMTSARGGKAENRERGSMHASCIAGQQEKKKITIVEVVKVGKWNSNPAVVARKVEETKSMQTCLLIVSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY11</accession>
    <name>A0AAD5XY11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SAT4_3</name>
        <name evidence="12" type="ORF">HK099_004770</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000347">
        <property type="protein sequence ID" value="KAJ3219237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY11"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF558">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="498"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="195"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="256"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="466"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="529"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3219237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="822" mass="92959" checksum="EFA575B66D686ABD" modified="2024-05-29" version="1">MDFKAAPAQREEVSNSYSLSLIAEMCSEKLKFEEPISAVKVELNFNPISCELEILENRENLIEVLKLSNPKLPLKELTSTALTKKAATTVRNGSSSEPDSLKEVKREISPSTERKSMEDTENVLEAKNADVVLPLKIVFSPLLTATEETISAEPKPLEKIVRKFEVNSTLDITENKENIKGLKKSTSNLYFERVSSSAQLTKERSEPENKNPRKRSSTLANVPRIKTENISTPNTKNNIFHWSKKVDNEEPKGFLSKSNNGSKTNLGSSLKRSASNSINFSSSKNLSPLLDLGLPNRKSSSLIHRLFQFTNHDSNSTSNDNYKIKTNLGAETEVLHFPGFSIADPITPDHNNLNKSEALYASRTNSTLSKFFHFNVSNTTPTSPALTASPRGSADNLQDTMLLLSTGASSSVTPIQSVPSTKIHEEENILTPIIQKFNVLKSHKFHNLEENTFFKDVLTSLHIKANHKDKEKDKDEESKNNTGISLSRSVSMEKLNYGIRDEVLGKGANATVKLAHQKIMNIEKLYAVKEFRKRRKEETEREYVKKVIGEFCISLHHENVIVVIDLIQDEKDRWCQIMEYLAGGDLYGRISKRTLTDKVEINCYFKQLMCGVQYLHSVGVAHRDLKPENLLLDETGRILKITDFGCAKVFKTCFEKTSRTVKGKCGSDPYIAPEEFDDDAEYESLKVDIWACGIILFAMYQKTVPWHLAKQDDHNYAAYTKKRHYEGYGFLSFDKLPEGPRSIIYKLLEPNPKLRPSTAEIFENYWFNAICYCHLVKTDELNNSCNKSFFAKSGSQLEDFNNEKSNPVLNEVNHTHLKLGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY20</accession>
    <name>A0AAD5XY20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000876">
        <property type="protein sequence ID" value="KAJ3210718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY20"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3210718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="37115" checksum="726B24721F784346" modified="2024-05-29" version="1">MGRKNANQEKRSDQEKQLQKSGSEANNENQASTEQEKIIENDKKPSKFAVTFRYVNALRAVATAGYSIYLSVLGFQNSLFIEYQAQGMLYATIVSLSLDVIFTIIRAFPSLQQKLKFKKTTKASRVGAWSVIAGKKSINRKVVVPSPIVSMVSNSVVNLPLHYYYLKMTKGEADEENKEKVKNTNDFGEEDNFFKKAVYQTFNKYSVGIFGLYGIWSCFAMYFTLTQLDLISAETLIQESISAVEGRPSKIIILLVWINVALNYALGVACTGIFLVYTIVDNMFVRPVRKIHSARTGSAKPKKSAALNEESEEKNNADLSNKVSNVAISNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYL6</accession>
    <name>A0AAD5XYL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000683">
        <property type="protein sequence ID" value="KAJ3213704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYL6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="204" mass="23347" checksum="4830B6937C018ED7" modified="2024-05-29" version="1" fragment="single">MKIHKKVSSTSIDVPEDFSNLEDSFEYFTAEDTFTDSSQKSINTKTTSLDYHASLFPIELSLQKQTKFQQFNDKKIAQKTEIKSKTEKTNENSAADHISLSQPDFSTISEIFHIDSNPPILPHIHHSNDSFFLSKVTEFNFAKYQVKDLSLKYQHDLNRILKNEKNHAETTHATNQILPFPLLKNSSNYFAQTASILPTVTKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ63</accession>
    <name>A0AAD5XZ63_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein Tax-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RIBC2</name>
        <name evidence="10" type="ORF">HK099_002694</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Microtubule inner protein component of sperm flagellar doublet microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RIB43A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000191">
        <property type="protein sequence ID" value="KAJ3222115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ63"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008805">
        <property type="entry name" value="RIB43A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14517:SF6">
        <property type="entry name" value="RE41410P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14517">
        <property type="entry name" value="RIB43A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05914">
        <property type="entry name" value="RIB43A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="353" mass="42495" checksum="6EC7A501A6C12576" modified="2024-05-29" version="1">MYRVEIASDKLQQAAVDRRRRLDEERKNRLFDPKARIIGIDVKALEDQIKIKNEIKDWEKLRDDSFNNQMSDTNKLLMHLDHQMANQHRNNSKNLEDFRAEKQKVHERRDFDLYDPNALKKDLPGRVGDFDERLKHQSNLQKFEGEDLKSTERSLEQKQQMKTWSIQGMYERELKKKQEEKEKKEFEEYKEIVAAKSRALQRAMDKQKADTAKNDFLFNQKLSEEKRKKEEEFKLNETEKNFQEIIGQVNGEILTENPDSFNIGGGHKVRVDVFKGFNNYQKHEVLVVQDYQRREVEARRQHEREVELEWAYKQEVLNRASILMEQDSEKKRRELAIKIRKENELKAKEEKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ94</accession>
    <name>A0AAD5XZ94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000368">
        <property type="protein sequence ID" value="KAJ3218708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ94"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="127" mass="14346" checksum="9CFC7BC187E91DF0" modified="2024-05-29" version="1">MHLLHSKLNGIVPVVAEVTNLIFKVILPVLTKSFPNPIILIYLKRKLESQKLTSLLALFIQHMPPLTQLKEVVSLPQTRGASVLYYKIIRPYGIKQEKGLDDAINEIKKSAADTMQEVKAEAEKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ95</accession>
    <name>A0AAD5XZ95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras- protein Rab-1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAB1A</name>
        <name evidence="6" type="ORF">HK099_006143</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000510">
        <property type="protein sequence ID" value="KAJ3215920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ95"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01869">
        <property type="entry name" value="Rab1_Ypt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057289">
        <property type="entry name" value="Rab1/Ypt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3215920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="196" mass="21671" checksum="34D38322D0711706" modified="2024-05-29" version="1">MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFVSKTVKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQETFNNVKQWLQEIDRYANEGVNKLLVGNKSDLVNKKVVEYNAAKEFADSLTIPFLETSAKNATNVEQAFLTMAKHIKDRMGANTTTGAGGKKEPLKIGSPVKTEAAGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZV6</accession>
    <name>A0AAD5XZV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">poly(A)-specific ribonuclease</fullName>
            <ecNumber evidence="5">3.1.13.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">CNOT7</name>
        <name evidence="18" type="ORF">HK099_000935</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZV6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000005">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039637">
        <property type="entry name" value="CNOT7/CNOT8/Pop2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10797">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0678">Repressor</keyword>
    <keyword evidence="13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="15" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="16" id="KW-0804">Transcription</keyword>
    <keyword evidence="14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="12" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3223585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="30089" checksum="9D68803E27092BF1" modified="2024-05-29" version="1">MSRESNLQEEFLILQDIVEKFPYVAMDTEFPGVVARPIGHFKTSSDYHYQTLRCNVDLLNIIQLGISFCDENGNPPPGCSTWQFNFKFNLSDDMYAQDSIDLLQKSGIDFKKHQDFGIDLLHFGELMTSSGLVLLKEVKWVSFHSGYDFGYLLKVLTCKLLPKEEESFFELLRLYFPCIYDIKYLMKSCKNLKGGLQEVADDLQIKRVGPQHQAGSDSLLTCKTFFKMRQTFFENKIDDLKYLGFLYGLSSSFPYQQQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y082</accession>
    <name>A0AAD5Y082_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ubiquinone biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COQ6</name>
        <name evidence="8" type="ORF">HK099_003552</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000232">
        <property type="protein sequence ID" value="KAJ3221405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y082"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051205">
        <property type="entry name" value="UbiH/COQ6_monooxygenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="17"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="382"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="507" mass="56882" checksum="5EBD720F0A63F33A" modified="2024-05-29" version="1">MHKLLTRRLSTAVDKTYDICIVGAGPVGLSLAAKIGNSHYTNGNKICLIESSDVLKSLEENDTFSNRVVSVTPKSRLFLEEIGCWNNIPEEKVYPYNKIQVFDSNFKGSINFNSRYDEETEVSKASTAPKECTPSSSYDPVAYIIENNVIRSSLIKTLKNLNNEIEIFNNTKVNEIILDKGSFNDEWPIIKLDSGKVIQARLLIGADGQNSPVRMAANIESIGWDYDQSGIVGTLKVSGCSTVAFQRFLPTGPIALLPLKDKYMSLVWTLPKNISNLLFNLKKLNLKNDKMIFKEILNTALKNPKEDLLYFFSELEKLNDGKINFQNISEADKLKIELELNAIDFKFEREWGIKRLDSEQGGISVHDTIPVVEDIVKNSVAGFPLRLRNCRTYIGNRIALIGDAAHSIHPLAGQGLNLGLADSEALGRVLIKAIKNGDDFGLDYILEEYNSERYIKNLLMISSCDILEKVFVKVPSQFRIFEDLISFGLNSLNKMDVLKETLKKYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y113</accession>
    <name>A0AAD5Y113_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GAR transformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001970</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-10-formyltetrahydrofolate = N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GART family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000161">
        <property type="protein sequence ID" value="KAJ3222755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y113"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.170:FF:000009">
        <property type="entry name" value="Phosphoribosylglycinamide formyltransferase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.170">
        <property type="entry name" value="Formyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369:SF2">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3222755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="207" mass="23406" checksum="DFAE331783450645" modified="2024-05-29" version="1">MSDNNLKSIVVFISGNGSNLQSIIDNIKNNTIKNAKIDLVVSNRSKAYGLTRAKENNIPTKILTLKKYKDENKTRLEYDLDLANLVLNNIKPDLIVLAGFMHILSSEFLDKFPNTNLINLHPALPGQFDGAEAIPRAFNAFKKGEIKHTGVMVHKVIKDVDRGEVICFEEVEIKNDDKLEHLEDRIHEVEHKLLITGINLILEDKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1D4</accession>
    <name>A0AAD5Y1D4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PBP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001098</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000129">
        <property type="protein sequence ID" value="KAJ3223453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050962">
        <property type="entry name" value="Phosphate-bind_PstS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42996">
        <property type="entry name" value="PHOSPHATE-BINDING PROTEIN PSTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42996:SF1">
        <property type="entry name" value="PHOSPHATE-BINDING PROTEIN PSTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="OsmC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="679"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="722"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="772"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="836"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="865"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="902"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="domain" description="PBP" evidence="4">
        <location>
            <begin position="148"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="969"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1126"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="969"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1048"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1080"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1140"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1162"/>
            <end position="1189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1303" mass="147040" checksum="7773C10696F61C64" modified="2024-05-29" version="1">MKLLLISLGGCSSLSVSSILKKQKQEISNFQVEVKGTREGDYPKPFKFIEMRFLVEGKNLDKAKVKNAFQLGINKYCGVHASLNAKISFEVEIKEEPLDFSKKSMVKIDILVEGGVSFIFILAIIASILLPIYVNESGNLSKIVKEYSIKSSGSAFPAAIYKNLFEGYEKLYSNVQYFNSYDINENFTEVQLELLNGDIIFASRESKLTNTVTPNDLNSETSANLGELTFPAFGTAIAIVYNLPFLKDVTLNLTSDVLGEIFSGNILFWNDKKITDLNKNANLTSESLIPVVSPKHKCNQAFFKYLSTHSKNFSSTLSDDWPNDFLNVQDELRVMLAVETLSNAIGFVTTNTLTALATSNHEFMVAAIQRTALEDPTLPSLENIKKAMEVHFTSENSSNIRIIDSVNKGSYPISFLQFAFTRNHYLFNNPKLLNQDEIKNQCEIVLEMVKFWNFTLQSKEASVILNSYGMVQIESSLRNNSLEAISLITCNRINLYKGLQKSIEQASYYIKNPLMLTWKKSTDFWSNLTIVFQEAILGGFLYVLMYGLLFFSTTACFLYHLKIYNDSLKEKKNKAVAKNFAQRLQKEQKEKSEDITEEEKFEEILAKKGPKSLKLLGTSDQKTKQARLSTQNLFAVISSLLTCLQLMHLSLSGSQLDLEYYPVYQFVSYGSLLFDKNIVYFWALTIGVFTWLFGMIFIISVRPYLQEFYPILMEKYEFLNKWLALFLPNYAAIFFTPTIEVLAKAFECRYTPNHVFISSFDPRAVDITCYSGVHWVMIIASLLFMNCFTIAVIRFSTILKAFRQIFDLKDEPWLIIYEPYIKCILVIAYYNVPHVAYFISSIILMSLTVALLYQFKPNAHRWFDVLRATLYGFNCVICVILLIIEVAVPENNFQVKSLIREIFSTVVLAITCAGVLFILYFVNKKFKPIISAEDAKKRRNEIDKLFKAISDGDAMGHWDSIEMLNNNGGSRKASNLLETPGLSNRRNRESFKSSFSEASPEAPGNDNFKPRSSRSYDANKPPRDILKNSVDVSEQDEEDSTPGQGDLEEAKRNEVSKFVDSSSLERKQSIVPPSFGPSINFISPSPSRKSSLAGGTTSSNGRRRSIMQSVISYGLGEPESLISSNLLTPNAKENRRRSYADNTNKPALFNPSLSGNKLIPNTVGNGRRTSYAPSDANTSNSQLTTGNNNLKNNYSVSKVSVAPSLSNFPWNDFRDLVVKAKLSGIISTDLSLSLLEEIENEDLFIVLLFKRSEGNFQKFIYLMNKKVSDIIGTKRYGNAAMRSSNSMLASSSNKGILMEEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y262</accession>
    <name>A0AAD5Y262_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000483</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000111">
        <property type="protein sequence ID" value="KAJ3223943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y262"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="34078" checksum="1DDA787B3DE3D7CA" modified="2024-05-29" version="1">MTLLQLGLGDQLNKLWDYSNPIETEKKFTELLLNTNFKDFEKSEIFTQIARCQGLQKEFQKAEETLCKTQNLFTDSDEFNCAKVRFLLEKGRILRSSKLPKESLKYFLEAYETSLNFPELSYFTVDALHMLGLAENETEKKVYWNLEAIKVAEGSSDVATKNWLGSIYNNLGWIYHDEIKFEQALRYFQSAYLFFLDLIKVDVNEDAKLKSKLKIAKWTVGRCLRSLNKIDEALEIQLSLNDGTDGYVNEELSYLYDLKGNIELRSVNAKMTLNCLTEEDLGEERYKKILSFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y407</accession>
    <name>A0AAD5Y407_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL43_2</name>
        <name evidence="5" type="ORF">HK099_008280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y407"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000002">
        <property type="entry name" value="60S ribosomal protein L37a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00327">
        <property type="entry name" value="Ribosomal_eL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050522">
        <property type="entry name" value="Ribosomal_protein_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00280">
        <property type="entry name" value="eL43_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003058">
        <property type="entry name" value="PRK03976.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="92" mass="10162" checksum="1746DA57E7B2AE4B" modified="2024-05-29" version="1">MTKRTKKVGVTGKYGVRYGASLRKQVKKMEITQHAKYTCTFCGKDSVKRSNVGIWNCKACKKVMAGGAYTISTPAAATVRSSVRRLRELVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSE3</accession>
    <name>A0AAD5TSE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002197">
        <property type="protein sequence ID" value="KAJ3199068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSE3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="75" mass="8329" checksum="2E1A6D540A60AD2F" modified="2024-05-29" version="1" fragment="single">ISINQPRKNRQKDPALVPEINPVVESTVEQVLQIFTVPSETSITDLNNAITEILPTNTTSTSTHSTDSPTYHNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU81</accession>
    <name>A0AAD5TU81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000917</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001230">
        <property type="protein sequence ID" value="KAJ3205137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU81"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="32"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="93"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3205137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="168" mass="19621" checksum="CD4ADE93542E58E9" modified="2024-05-29" version="1" fragment="single">KIKKKHNMSNSGKRCFIGKYLKKKFKAGNKRGLSWDTDDSALRGFFEKFGAVADAKVIVDRDSGRSKGFGFVTFETTEEANRAIDEKDLELDGRSINVQMAQERSAREDRGDRSRGGNRSRGGDYYRGSDSYRGDRRDDRRDDRRENRRDDRRESSPRRERSPRRERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUP5</accession>
    <name>A0AAD5TUP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DBP9</name>
        <name evidence="13" type="ORF">HK099_000709</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010001179">
        <property type="protein sequence ID" value="KAJ3205744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUP5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17961">
        <property type="entry name" value="DEADc_DDX56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF21">
        <property type="entry name" value="DEAD-BOX HELICASE 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="107"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="288"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3205744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="654" mass="74553" checksum="B0D571C94A8A5CC8" modified="2024-05-29" version="1" fragment="single">KKISNNVYDNLNTESDNLNKKKDEVQQIIEEPKELIAEDSTNEHSIKENVNIIEEDVSKEEKKSIESVLPKNTFTVSFEEMELDDRLKRACARLKYKKPTLVQQTSIPLALMGKDIVARAKTGSGKTAAFCLPILQKILQNNTNLSITSEHALRALVLVPSKELANQVYDVLKSLSFYCQNVVRLLNACDCDGSLKSENPDIVVATPTKFLQLIDSQDTLESLVIDEADLILSFGYEEDLNKLVNFFPKALQTFLFSATLSCDVDRLKVLLVRNPAIIKLEDADEEDLLTQYSLRCTEQEKFLITYFLLKLKVHPFGTGKSLIFVNDIDRGYRLKLFLEQFAIKSCVLNSELPFKSRHHIVQEFNRGLYDYLIATDEVKNDEIDLENEKKVKKKGDKEFGVARGIDFINVQSVINFDFPGNFRGYLHRIGRTARGVGNKGYALSLIEKKKIIPGDNSKKVDLSPTKEEATLLKIQKKQQKIGREILDFNLDMTQVNGFRYRIEDALRIVTKTSVRDARLKEIRNEILNSEKLKAHFEDNPRDLEALRHDKQIHPQKILNHMKHIPTYLAPTKKTSIISKNISSSNEPVVTQTIANDSVSQQKSNGKKRNIEKVKEEDVGIVKFDATKQGTRKNKNYNVNKKLKVDSLKSFSVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUW6</accession>
    <name>A0AAD5TUW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001123">
        <property type="protein sequence ID" value="KAJ3206455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUW6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3206455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="333" mass="37847" checksum="74DE798792AD15E7" modified="2024-05-29" version="1" fragment="single">VEKLSFNYGDDVSLVTVGDIPLNIHNVGLFVRNMFDYDVDYFDKLKNAHQFQVLTESNKTSLSHRKGIYLTNVEKDDNNICKFNLLRCSTNLDGPTETFKKVDLEIVSKVNGIANLYFENPYTLNHALAQIYENSKTFGANEKAKDNKARIKSHSDKTKDMPSNGLIAFCTFYSAELFERAVKNSRDDFHDYMYKNGSVLTKLSFKLKKTVEEQTGLKKQFTITLYPNSLFLIPLSTNRMYTHEIVPSGLPVDKIPTRLGYVIRCSKTKAIHKNGNAYICEGKDCVLLKRPTEKDVADIKALYFEENTTDNVINYGAVNFSLNNGDYQPPNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV63</accession>
    <name>A0AAD5TV63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">IQ calmodulin-binding motif family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001088">
        <property type="protein sequence ID" value="KAJ3206962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV63"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33504">
        <property type="entry name" value="NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33504:SF2">
        <property type="entry name" value="PROTEIN MFI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3206962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="69333" checksum="FC07B7E6AE3A9E6B" modified="2024-05-29" version="1">MSKIEPKKNDTIQLLGFNPLELIEEIEFPNDRYEETIRRSKSARIRAIRRLPFKEVGVYSVVNVDHPTIIAPKPITAPRFKSDPIVDSNKTDELNRHELEELESKVKYQLSRMAAIITIQAFWKTILTRRKYLEVVCFGMTRKSIATTSHTMPGFDNLSDALSVQEKLLKKYHFYCQIYDRMNRLPPTYSFFCATLIQSYFRMWRLHQAYRNYRDAVALREAGLMLDELKRIGGNELVEKDEAEVAVRKVQKLWKSYYYRKIYKFFRDLIKFRQSGDPKKMLKFINPTESNLIDNATGLHIKFRLGGYTFPPTIFYKIFVHNSLIDMNAFSPRDYTQECNKLRNPRVKFNKVDIDGLNDESKSSHDGWYQRTENNGWRPVSEKIYQEELESFEFSKSAAFNQISFEKEEKKINFHRDKLIRKEDVEKKRKEKKLKWLKKLYEDGKEGMGTKVVMENLDLKTVNEDFKSFEKDKGNCKTLTKEELEDFGINFENEEEDFKLLSNWSKKLDFEQYFDDWKVLATSSFTTTIPNLPKNSTGIFKKVVENDFVLQDSILESFKKHEIINNYDKNYYEHKKKIKESLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVH0</accession>
    <name>A0AAD5TVH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycerophosphocholine phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GDE1_2</name>
        <name evidence="4" type="ORF">HK099_008262</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000894">
        <property type="protein sequence ID" value="KAJ3210381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVH0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047389">
        <property type="term" value="F:glycerophosphocholine phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051578">
        <property type="entry name" value="GDPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="3">
        <location>
            <begin position="580"/>
            <end position="941"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3210381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="942" mass="107332" checksum="A580B2F83C318BE2" modified="2024-05-29" version="1">MAVKKVLQKFDLYFGKFSDNFDEVTAEAISKNMQTAESLQIKLKDSSLRLQNYILKQRKLTDFQANIELEQILKSDDKIQLKQFLEDLLESNTTPEEESTFDFFKFLILNLILKFNSIQCLNLIFNDPAWINILNFKPKISNYTVLHRLASHTLTSNEKVIEKLLSLKDWNTDFFESKDILGNTPLLYTISKHKESSFKNSFQILDHFLKVQLPVTFFDEDVITSAIYNGNAKALEKMLFLDNGEPRKDSFFSNGNFNQAVRFACSKGYDDVVEICIKRCDALRIDFDECNKNYSFLHLACRYGNYKCIEMLLKKINTDNMLSVNHSGIYGYTPLIYAAIFGDALIINLLLSNGANIEQADVFGWRAVEHAIYRGHLQLKTLLTPERSFEAPSFNFLLASLKCNELLTSTTTTTVILYKGSIDHRKNLPFYKLHEKNIPEHLRAPSYSISFRIESPSCGIKSEVLTVDLRNGNPNKPQVAIPFVFKFDIFKQSSIEDLVLFVQLKTSLADSILGSGLIEMTNGTSLWKERSSFGGTFKGKIFYLNAEGFSVILEVFFDVTIIFNKYDPMEYTKKPEFHGTRIIGHRGLGKDLPLINGKQVLELGENTITSFLTAGRLGADLVEFDVQLTNDFTPVIYHDWTMGKKGNNFPVHSVSLRNFLSSHPDINPALGSLFNETIQRSPVGRLSRREQLGDNRFGECSLGIEIEERGRNRTRGLPVSRTLSEITEFRLKFSSFENEKWPSKGNYDGTIQEAYPTLEDMFKKIPKNIGFNVEIKYPKVDEAEKDNLCMSELNFYLDTILNVTQNNLLVEPNMIPSDTTEREIFFSTFHPDSALGIRLKQKKHSVFFLTDGGIDISPDHRCNSLRQALKFCQLWNLQGIVTNVDAIIGNSMPIIKKFNNNGLKVSSYGFKNNDVQHCKEQVDSGINNIICDSVNKIKSGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVJ1</accession>
    <name>A0AAD5TVJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001045">
        <property type="protein sequence ID" value="KAJ3207599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVJ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3207599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="336" mass="37328" checksum="6DF677A4E2611299" modified="2024-05-29" version="1">MENKTDLPSYKERLSTVNSFNEFNEDSVSPEKILIDDTLDDHIFGNDKRDTVDSFDNPELSRLAGIYTTWLTPSLFPFFAFECMKRYLQCQGIMHGNLFVLTLAAPFCFFLQWLLVWKFSLGFIGSSIGLTISYCLLPILLLIYIYFFTSCESWGGFDSSEAFNLRLILQFLKLGFSGVASGWIGEAELAAQSIVLSSCVCLELISLGIAIGATTRWLWTNEQSVVSIVASIMPVAAIFQFCDGFNVVGAGILRGCGHQDVGALLNIVAFYVVGVPVAMLTAFKLNWGLFGLWAGLGSGLVIVSIFQIYWILKIDWKLEAQKAQYGECNESSIETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVK1</accession>
    <name>A0AAD5TVK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000983">
        <property type="protein sequence ID" value="KAJ3208652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVK1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="700"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="828"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="495"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="451"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="828"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="854"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="864"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="875"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="982" mass="112808" checksum="DEDBD2CD6852129C" modified="2024-05-29" version="1" fragment="single">RQRSGSPLGGTAVAHYSEPSHAPVPAHTRHSVYNERNYDDRPYSYDQTFNRQQSLNREAYHLQSRSHEPHYPHSIVPQPLLLQKQLKQEQNQLYFTEKPSSLKQLPITERPLSLHHQSITDRHHPFEQRSNISDQRRFTEHQTLDQISHYENRQSSSSENKHLHFQKTMVPYTTQKPPTNNKSNISESKSHYDYSTKEFPGSSKITEFPVKSFHADNYHRNYTNNVQTKNFEFKTQNSQSHNIPVQQKKKFDPFDEKIKKHLVYSSSPASSNNSSFSLHNLYDNQKKIYSPQLAFQQQTHSTFTVNDNSRLKKSSAFNLDSLVEIKSTHTINTNIPQQSKLNDISLTKNAQSFGMEFLLATPKLTTSTTTTTIRPPTPTETAVSVTSSKKRKTITNKPVVKKVLSEGDEETEEEDEDDDDDSDKYDYKKRSGNAKRGRRSPTRFAPKRNKNSTNSKSSTGSKKNLTSIVPPVKHNPLPSLLHNLDNTTSYRFTRRRNEEKLLQEKLLKKREEEKENLKKLNGLVDEKKVLVFDKSRAATIPDLNLDSIIDFSVPQSDGECTRLVTDSVAELRTAVKVAKEWSDEQISRLAQGLKKFGRDFGIIRRYEIVTDKVMLFEEKKNNNLEEEESIKMEEGDKLEVSLLENETKLDAPKEKIGENNAELIKVEEEQKNFNLKKEEELVKEENNLIKVENLEKKNTQHLLSNKPSLLREATPNSSSSLENDESESEVNNGTTKSLMGSEGELKTEKLKKKKKCLENKNLTINKSVKEIVEYYYLFGNKFKKNNKIISAKFQFRQKKAREKEAKKFQVIFEEEVVLCRNKENKKIENSHEDLNSDKNNDEKDDGGSDSSNDESEKKFKINENVENVVQNDSPETLKKNKKKDQDNFSKLLEVAEEETGSSTSFNNCSNPVTPTSTPTIVMEDGSKFQDLSSLPIQSSIDILNKQNFQLEIEKKSNNNNSNNFGGLKEGFLNQNKIASFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVX5</accession>
    <name>A0AAD5TVX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001296">
        <property type="protein sequence ID" value="KAJ3204479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVX5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1040:FF:000003">
        <property type="entry name" value="N-terminal acetyltransferase A, auxiliary subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1010">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021183">
        <property type="entry name" value="NatA_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF2">
        <property type="entry name" value="N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12569">
        <property type="entry name" value="NatA_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000422">
        <property type="entry name" value="N-terminal-AcTrfase-A_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="571"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3204479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="842" mass="99289" checksum="5BFAC204C9C1D486" modified="2024-05-29" version="1">MKGLFLSHLEKRAEAHEFIRKGLKQDLTSHICWHVYGLLHRGEKNYEEAIKCYSHALKYDKENMHIIRDYSLLQVQMRNFEGYTDTRYQLLQLKPNNKLYWIGLAVAHHLNNDHASALHVLDTFETSLNELPVNYLDYEHSEMLLYKNLILEEMGDLKVALTHLERIKKNVLDLTSWKESKARILMKLKNFELASIIFSELFESNSDSLEYLKGLEECRGLNRGQPNENVNKVIAFYENLKNMYPKSHIVQSVPLFYTKEENFSNALSEYLKPSLLKGVPSLFVTLKDLYNEEWRIELIYQLLIKFYDNLVNIQKFEESEEELAAPTATLWTAYFIAQHFDYLRDSDKALEWIDVAIDHSPTLADACMIKAKILKHAGDKKSAAEAMNEARELDLQDRFINTKCTKYMLRNNEDLKAKETIGLFTKADVDTIEDLKEMQCMWYFIELGKCYSSQYNFEKSLKTFKFVDKVFVDIFDDQFDFHSYCLRKMTLTDYGKLLKTEDTIKKNKFFVKSSLGALNCYEKILDKKLGKDSNIFNGESDESKLSVSEQKKLARKQRKIEEKLLKEKFEQESKNKENTKTNREKTDEKKSNADTKKIEDDDPEGKKILELDIDIILKEAIKTFLEPLLEFSPSLIEGWCFGIEFYTRQEKYLLAWKCLKTGVKLSKFDPEIIKKSVKFLHHFYENFDNVNATVSEIFFSELMEIDPFELNLQDEAKNKELIKTTLDKLMSKLENFNTTLHQFVLLELHLELFNKDSQEAFINFQNYFKGKKVQTIRGWECKRFGWEAEFKLNEEKDDKIVLIGMDMAKKILTYIRNIKEFDDKNEILEFFKNFFVKFDALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW60</accession>
    <name>A0AAD5TW60_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000903</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001229">
        <property type="protein sequence ID" value="KAJ3205146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW60"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3205146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="35687" checksum="5050D6E988011267" modified="2024-05-29" version="1">MNKFIQSFSNKSAFTTFKRNFQTSLNLLENKILILKFQPPALRTDLEFILKTYNPIKFVYPHGMNRRTKFVFVELSEDNSFKAIDEIHLKKRFNGVLLQLQYSNKEHRIAELVLINVSYKVTKEELAKYFDKKKYGVLSIRLLTKKNKRNHEVGTAFVKLNSDFVDDFIMDYNNAVLKCMKIAVLSNEDFNKELHRQRVLRFTSNRLSDKVKHIREMMNLVKEQQNASFAEIKKKNEMENACFELGTADIVLESPEKYPVKENILDKKDIDEKEIFLKGEEDEVAKVASKSWKGSGNHWKDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX89</accession>
    <name>A0AAD5TX89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000674">
        <property type="protein sequence ID" value="KAJ3213803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX89"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1095" mass="125823" checksum="D7EE1D93F7C02BF4" modified="2024-05-29" version="1">MSSQKEKDDQTTVFSIKNEIITEHERMEEFSKTFEELNSKQPETEFDEFNHVNKATTNPRPSLVTLEGSDKQLQLDFEREFNRISECVDKNLTANLNYLNFSDSLQKESVSSVSETQEKLKNCVFDNSSNSYSFERYIPNFFPSLSADFVSNEKLDELLNFYDNQSNKESKVKESINSAAPKNLETILDSTMKLFEPLQNINDKEFLQRSVANEIDNAALEEAKQDPRSQGEDALNNGSNSIETINKKKKKKKRKSNLTKSTVDSNVIGRLPSNESFIEDEIDTTSVEKLVPFSRNDSKFDVENCYQNESIKEVNVSNINNISKTPETETLINKDLAIDESLISNSKEIKINEKLKSATPEKNYSNKNATAVQNGKDKSNIFEEQAFDRFIIVLPSFIPNYFYPGIIEEILKTESYCLEYIERKPVQNHYTKFYYGEILRIGITVNPTKMAAFNNLKLGDRISIIKEIFHNYFETLIKNPTLNKELKDNLLKNQSNLLKVFKDIRLGESSGANEESNDSPSLLSNEEKFSSCKFFYTNPELPQIVMIAAITEFAIPLLKIILEQDNINPSNAKSSNTFNTINKYDLVGLKYLDKFSEKQARILTPYPVGQFKYQNSLESISRECEKGWIVMVVKNINAHKDIAEIVDNFFKVECMNNEESINNKYELSKKELQQLNILVSQSPELAYNQINTFFKDSELFFGSESACENKFLPQDYLTQHINKTLLSPAPPVSTICLIPKNLFGILGTVIQRLIEESFDITGLKLCEKSEIIKQNFFLFASQTENKTVHQNDFLELVAKEPFLILCASRVNAVKKMLELIEMLTCLSLNHQNNQKTLPNGYFVNQFGFASVSNGFNNNMIFISSSLKWSCKHKSMFFPEGQAYEVISTTLYGELRRQLLPFWSHVPTVFKEFKETEASEMYMENKIEDSEKNYIPEINKDSELCFILYLSTFDTTIENFERWGKMINLILNLESKEKNTVTPVNIRKISYKESVLNSKVEDRLIKEPKLTLVGLKLLMCSTGIINDFKNFLEEKDFSKFEKMNKGPCLAMVVEGKSALEEVNVVLKRLSKEMVLVSKNLEMAGKQWPLFMESLCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXS0</accession>
    <name>A0AAD5TXS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">14-3-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BMH1</name>
        <name evidence="3" type="ORF">HK099_006639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000589">
        <property type="protein sequence ID" value="KAJ3214819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXS0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08774">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="2">
        <location>
            <begin position="325"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="542" mass="61384" checksum="8C0FF937DE92CCD0" modified="2024-05-29" version="1" fragment="single">MHNVSLRKPALCNQSLFLLKASHAKRAQKHPATDIVLRTIEDHVISHEDNCTKFRLTCALLLQLSGYSVTIYTKASPDSWSTDEKYTSPKAVASLNEYRNQEWDQISFDTFKKLVDDKEVGLMLVPALEYSKNTIENLWYENFVPDFQEIKAKDLPVGQNYGFKFQTYCINVPKYLQWVLNQFKLNGGKIKHKTFKSIHELNIDNPDVVLNCSGLQAQSLNGVNDKLVYATRGQTVIVKAPKVYYTVTAGDAEDLQANDFTYVVMNDLQPCTKTADAIIERCVKLCPELLNEDGKVDIIGHKVGLRPSRIGGVRLEGKVERGNSREKNLYLAKLAEQGGRYNDMQEFITALFKDLAVSNEAPTVEERELFAIASKNVVGDLRETWYTIELIVKRLRESESDEEKLQTALDYQNKLKDEITLYCNLVVDLIDKNLIPSTKKDVAALIFFHKMKADYLRYLAEISTEEKKEQLAVLAKLSYTTAADIASTELPPTHPTRLGLVLNYSVFHYDILNSVEAASIIAKQGFDDALAEIDALEEHSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXY0</accession>
    <name>A0AAD5TXY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001625">
        <property type="protein sequence ID" value="KAJ3202080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXY0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF108">
        <property type="entry name" value="PROTEIN CNPPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="346"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="630" mass="72980" checksum="A4E0CF8EE03E1149" modified="2024-05-29" version="1">MNSTNYQINPTSTVLPYGSNYNIPPAAESSFSQLHQQVNNKIKTNENPTQIVSNNSNSEILLHDKRNLNNFNIPNQNVSSVQQQLQHKDSFYSDQFLEVGLLPQHHQQPQQYPVSNTGFNQTAVAIKPANFDDYQSSNTEQIIYKQNVKKIQIQQQQLQHQNFFLSSHQEHVNFKSIKMDKGVYQLNSLPSSEVGKVENSTRNLTANCTDALHNNDLEGSKKNISAMITSSPTTSEQCFSLPISQLDNQKLLLKKFWLKNNIKVQNLNSNFDFPKIFTLITANGFKKKFYINLINKVVNIESHNQLKDDLIEYTEHFLSKTFPYIPDPQQTNIRGSQDQQMKMVVNKKKILPTLQQFLRVIFNKTKLSLSTLATAIFFLKKLKLNHPNCKGSEGSGHRLILASIIVASKYNYDDTFDNKAWQTVGNGLFSLEDLNKMESEFLLYLNYKIFVKWEDWMVFCSELELDIKEYFFHVDGSVERLWNGPLVFELKVWDEVDELGSSQQYSRNINDIFNTSSVVYQNNAVFWKSYSALAQQHNPVVLNSDNSNPSSSYYGDYLPTENYDEDSLILHQQLHNPMQNHFQKEQLILQSFGNTGLLRATHHQNFVADQIFQKKFEYDHNFQKNNIRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY47</accession>
    <name>A0AAD5TY47_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AFG1-like ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000879">
        <property type="protein sequence ID" value="KAJ3210645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY47"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040713">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF6">
        <property type="entry name" value="AFG1-LIKE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3210645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="51758" checksum="EDD3E890AC88C13B" modified="2024-05-29" version="1" fragment="single">MPQDCLHVDICAKRFSTSNLIQSPFQKGPRMHYQSMLESKKLRPDYHQMETVEKLQNLYEKLLNYKPKNKEDGFSWKSLFGFGKKPVLDNGFPKGLYMYGDSELVANSQFDVTGFSDILYNSTSIPKKRRVHFHNFMQDIHVRIHELKKVDPKNPDPISKIADDLVEQAWFLCFDELQVTDISDAMILRRLFTELFNRGVIIVVTSNRHPDELYKNGIQRESFIPAIQLLKERLDVHTLDSGIDYRKEKRETYKVYFCPIDTYNQNRIKKIWAGLLKGNAATPSEIKFLGRSLQLSETYKKNCKVTFKEICENPLSSVDYLEFVKYYDTVVLTDVPKLTLSQKNEARRFITLIDALYENKVKLIMSTEVPIDQLFTGDEEDFNGRFNNIPKAYGNWIMAPEKLKSAVFSSEEEIFAFQRAVSRLTEMQSTDYLGKELKFVLENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYE8</accession>
    <name>A0AAD5TYE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007932</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000817">
        <property type="protein sequence ID" value="KAJ3211708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYE8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000952">
        <property type="entry name" value="Replication factor C subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000028">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF9">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="83"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3211708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="356" mass="40579" checksum="F197887329D09B5D" modified="2024-05-29" version="1" fragment="single">MTKNLDGSMHELKESDDLMELDHDDETISNLMRLKNKGKETLRVGMASDNLPWVEKYRPKGLDELISHNNIIETITRFIDENRLPHLLLYGPPGTGKTSTILACARKIYGSNFKSMILEVLLFLNSTSYTNTIFCQLNASDDRGLDVVRDQIKTFASSKTMFQDVGFKMIILDESDNMTQAAQNALRRVIEKYTKNVRFCLICNYVNKIIPAIQSRCTKFRFAPLKEDQIQIRLNTIILDEKVNVDNSGKEALLRLSKGDMRRALNILQSTCAAFDEVTALNVYKCVGCPLPEDIESIVNWLMESDYNSAYFSILKLKTIKGLALADIITEIFEQLTTIELPENVRCYIYDKLADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYI3</accession>
    <name>A0AAD5TYI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="2 6">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005929</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the DTD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="2 6"/>
    <dbReference type="EMBL" id="JADGJW010000486">
        <property type="protein sequence ID" value="KAJ3216298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYI3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051500">
        <property type="term" value="F:D-tyrosyl-tRNA(Tyr) deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.80.10:FF:000001">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="entry name" value="D-tyrosyl-tRNA(Tyr) deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00256">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472:SF5">
        <property type="entry name" value="D-AMINOACYL-TRNA DEACYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="D-TYROSYL-TRNA TYR DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="DTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="151" mass="17159" checksum="FB04C75C3EB3B60B" modified="2024-05-29" version="1">MRVVLQRVTESSVKVNEKIVGAINKGICALVGICNDDTEVDQDYIVNKLISLRLWDFEGKSWNKSVVEKQYEILLVSQFTLYAKTTKGSKPDFHNAMKSERSQEFFNTFVDKLKVKYDPSKIQEGEFGAMMEVSIVNDGPVTIVLDSKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYS4</accession>
    <name>A0AAD5TYS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000927">
        <property type="protein sequence ID" value="KAJ3209690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019049">
        <property type="entry name" value="Nucleoporin_prot_Ndc1/Nup"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09531">
        <property type="entry name" value="Ndc1_Nup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3209690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="285" mass="33594" checksum="C0E08DED75A301F6" modified="2024-05-29" version="1">MNVIVEESVRLRMFNIEFFFKCLVGCSVNILCWEFQLFLFHTVFTKPLNLFAKSNQLEALIIGLSSGERQKNSKEEFLQYLAFFELWNISKFEYKKKQIIFDSATQKFNYWAGITEACLKVLSNLEEDLSLELKSSSEVKKVYNVTSNNEPFKVGFSNKDSNFSFTKQSNLTKRNVYSDTVVVTEIKPHNKIAEEKMENHKKDVLLKRVPILRNDLFKEKKNAGMDDVILSNKNQFLIKKKFLIFLQNFMGEKKFNYMFQNLLVYKVLNIFSRCQLQIWACQCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZG5</accession>
    <name>A0AAD5TZG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001082">
        <property type="protein sequence ID" value="KAJ3207059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZG5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019026">
        <property type="entry name" value="Peptidase_M64_IgA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09471">
        <property type="entry name" value="Peptidase_M64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042209895" evidence="1">
        <location>
            <begin position="16"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="588" mass="67310" checksum="D43BC8569FD1D4EF" modified="2024-05-29" version="1">MYLLTFTFLIGFIYALQIPVNFQKVDLQLDGFVGAKIEYTPSNNRCTLLEKYPVQNMRTLNFDNQYEVYRKKLDQDKYKSVTEKEVIEINALNEKSFFQALYSVCKFGLDIEDDEFFVQNFNNFVDDEEVLKIIDSGASENRVDVVFMGDGYTSAEKSKFFDDIKRLTKDMWTGVTFRSVKPLMNVWAVFKPSVESGIGVSGKPKNTPFGLYRDGTELRGIYCSKPQQARRSCKVTGSYACDFPSLIANDDYYGGLGGEFTISTKSILSGTIVLRHELGHNFISVGEEYDGGDVYSGVNAAPTSTLNNLKWKHWLSEPNNVKEEKEVLLLQAYPWYDLAKGEIALQFKSEGVLKRWMLQISASGVESKGSLVVTLDGKELPWTPRGDFDREFYRWEGNEGFSSGSHSLIIKQGFPAVEGSPIRQLCNVEIHEFADEPLFHLNNTFVGAYPTFNSRKQKTYRPTNEACLMRNMKSTSFCPICQEGLWLNFLNRVNLIDEVKVECKDNEGVIKSRFVPLGHLRPENEQIDGEELSIKWFHNGVEELHLHNLNEFKSKNGDWEVEVKFKSLEIRKDEKNLTFDKKSFKVEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZS7</accession>
    <name>A0AAD5TZS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CBK1</name>
        <name evidence="16" type="ORF">HK099_004810</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000351">
        <property type="protein sequence ID" value="KAJ3219116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZS7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000024">
        <property type="entry name" value="Probable serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000192">
        <property type="entry name" value="Serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF76">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_135, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="85"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="15">
        <location>
            <begin position="381"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3219116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="456" mass="52182" checksum="B813581C50D24D98" modified="2024-05-29" version="1">MSFSSSKLNDVEMSEGSMSNQASHDSLAFDRSTGGISQFTIDRATAAKYRLEFFYKQSLAETVDREARESEFLRLRRVKLGVDDFQTIKVIGKGAFGEVRLVQKKDTGKIFAMKSLRKTEMVKKDQLAHVKAERDLLAESVNCEWVVQLYYSFQDAEYLYLIMEFLAGGDLMTMLIKYDTFSEDVTRFYIAQCVAAICSVHDLGFVHRDIKPDNLLIDSRGHIKLTDFGLATGFHKTHDSSYYQKLLNQNTSKESKFSDIGTAKNIDLTLSRQDKIATWKKNRRTLAYSTVGTPDYIAPEVFSQQGYGAECDFWSLGAIMFECLVENAHDTYRKIINWKEFLSIPDDIHLSREAEDLIFRLLCDSGSRLKSQEIKSHPFFMGVDWENLRKINSPFVPQLLSITDTSYFPTEELNGMMQDVNQDLGGLDNSFSSNPKKDLAFVGYTFKRWETIRSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0D3</accession>
    <name>A0AAD5U0D3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000304">
        <property type="protein sequence ID" value="KAJ3220428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0D3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="85" mass="10193" checksum="333156B4C00F51F3" modified="2024-05-29" version="1" fragment="single">SYKTINTDDLKAINLTFFNEIERLKNLKPYKNNFQDDKNQHVFTIFWVVKDSKTFGFIFSFNLDPTFLKDFDDNLDFINLINENT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0N8</accession>
    <name>A0AAD5U0N8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000510">
        <property type="protein sequence ID" value="KAJ3215914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0N8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="89" mass="10241" checksum="4B3135F021147BB8" modified="2024-05-29" version="1" fragment="single">MLLVEQAALSSIDKLRHSFIVAVYSKTTMGDPALHFVVEQEELNGEQLCCLVELLKKFRNVDGFYVDVSYGSEVDWKNEKVKFGWKQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0P8</accession>
    <name>A0AAD5U0P8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4</fullName>
            <ecNumber evidence="6">3.1.13.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Carbon catabolite repressor protein 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Cytoplasmic deadenylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="22">Glucose-repressible alcohol dehydrogenase transcriptional effector</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="primary">CCR4</name>
        <name evidence="25" type="ORF">HK099_004427</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CCR4/nocturin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000310">
        <property type="protein sequence ID" value="KAJ3220225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0P8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09097">
        <property type="entry name" value="Deadenylase_CCR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000037">
        <property type="entry name" value="Glucose-repressible alcohol dehydrogenase transcriptional effector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF100">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="17" id="KW-0804">Transcription</keyword>
    <keyword evidence="16" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="24">
        <location>
            <begin position="278"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00030493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00031469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00033317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAJ3220225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="620" mass="71144" checksum="18F7A4FCE0750831" modified="2024-05-29" version="1">MENQQHFTAGTTTFYSQPGVSFNSPKITPNSPQQHSYSPQQQRQYLSQFKATLYPTSNSPVPSTLNLQNNFQKQLDKQILSRSSNSPHHHARLAIATARQNQNVEEEQQQLENAKASDWTAIDLGGMQIRNLSFEIFKYEFLTTLYLNHNNLTRISPECHKLRNLKVLDLSGNKLASIPPELGMLTNLVELLLFDNELTVLPHEFGALFQLDILGLEGNPLSEPIVSLSQKDGAVGVIQYLRDSCPVGPQPPEREWISLEEDVSSASNQIDNFTLLCYNALCDKYATPGTYPYTPSWVLNWEYRKDLLLQEILNYNADIVCLQEVESLQYDEYFREQMSQHGDYDGIFYPKSRARTMDEYSRKSVDGCATFWKSSKFSLIEKQLIEFQQIAMQRPELRKTEDIFNRVMVKDNIAVVTLLEAKDTSSRLLVANAHLHWDPQYKDVKLVQTAMLMEELQHITHAFCNLPSRHPQHKYLQQNPLRLPTILCGDFNSLPQSGVYEFLSRSTCSQDHEDFGQYKYGRYTSEGLKHKFNLRSAYSHINELEFTNFTPSFKGCIDFIWYSTSSLVVTGLLANVDETYLEKCVGFPNWHHPSDHIPLLSSFSMKNINVGNNKNTNNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U137</accession>
    <name>A0AAD5U137_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000261">
        <property type="protein sequence ID" value="KAJ3220956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U137"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="110"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="310" mass="35871" checksum="1A0AE6FFA1C935C6" modified="2024-05-29" version="1" fragment="single">MEKLNLDNLDEAKQQECIKEFRILLGDESQNFKDHVLLRFLIARKLNVVESYKMLLKNIQWRKENDIDNKIKVPLIHPGNIPIPNNVRGFDSVPDSTYYPPLDSNVKEEWKEFFPYFGGGCYHSRDKDGFPIYIERIGKLIPGKLVEVCSVETLMDFHLHNVEFLHKILFKECSEKSGRDISMHTIIFDLEGISFSHLKAMHLLQSLSEIDNDNYPETMRRLFVVNAPSLFSYGWKMIKGWLDERTIDKVHIIGTSKSEIAETLLNYIDIKTLPTLYGGNCECSHMVGGCCPILSHPDFKHLLKNNKIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U143</accession>
    <name>A0AAD5U143_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L26A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL26A</name>
        <name evidence="6" type="ORF">HK099_005385</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000416">
        <property type="protein sequence ID" value="KAJ3217640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U143"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_A">
        <property type="entry name" value="Ribosomal_uL24_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3217640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="126" mass="14633" checksum="0069C885D33C4DE1" modified="2024-05-29" version="1">MKYSTDVSSSRRKSRKAHFSAPSSEKRHIMSSNLSKELREKYNARSIPIRKDDVVKIVRGKYKGREGKVTQVYRRRWCIHVEKIQKEKANGATVLIPIHPSNVAITTLKLDKDRKDLLDRKNSSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U175</accession>
    <name>A0AAD5U175_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000253">
        <property type="protein sequence ID" value="KAJ3221078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U175"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041918922" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="388" mass="42428" checksum="099F35DE16B37899" modified="2024-05-29" version="1">MHLTQALLGILALSFAAALPQEPVETETTLLPSESSTVQSQTSQASIPPETFSTSTLPPSETNTLAPSTTSEAISEPTTGGETLRCSGRTARKEVRQMKQDGDWDAFIGAYMSLVSDGTLASYVNQHVQSWGFAHFNAHFLPYHRIFLKKFEEDLQSRGARYLPYWDSSADSQDLLNSQILTAEFFGKLASDGTIQDGPFSRGNYSTPVDGLPLTRGYKEGDTLYAFPLIQNAINNPSFSGMSEDIEYGQHAVVHSIIGGASGSMSVQTSPNDPLFFLHHCYVDYIFYKWQLQNPGSPFEADNYNLGRMTPNEIIAPWNVPVRNAWTVDQACVGYEDPDPNVVKVAGNGTIRPPSNATAWLNNAGANKTVAKTVAKKATENVKKVKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1E2</accession>
    <name>A0AAD5U1E2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Late embryogenesis abundant protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000702">
        <property type="protein sequence ID" value="KAJ3213508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1E2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.700">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10418" checksum="59FC19481BF9B5D9" modified="2024-05-29" version="1">MMKAANNGMQYTKEQANNGAQYTKELANDGLEKSKDAINRGVQITKETADNGMQYSKEIANDGMQYSKELASDLLKKFEDALNNGREYTETKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1G5</accession>
    <name>A0AAD5U1G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000237">
        <property type="protein sequence ID" value="KAJ3221313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1G5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042173485" evidence="1">
        <location>
            <begin position="21"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="36101" checksum="7E2AFE101112F183" modified="2024-05-29" version="1">MKFPSILQLALTVTLAFCVASELGTCTPNIQKCSEKKFLLAWEMTNIGSISAGNPAALWARVYVDGVLIAQTGVPGNTFEITNVAPSGTAWRTDPNFVGGPNWHTNQFNLPGCPTASNNQPWQASSANSPTNPSVWGTADKPYGVWYPSCTGGANSNWARFVFSVSATTEPHQIKVKTSVDNTFTLYFPATSTSHSFSDWTTLKEYTFVADNSHPAASPPECKCTPDSIGGVWCNHGSPYFYQCAEDVSPPAPSAPGWRQKICSHGTVCDAGIASQNYYADGRSYFDQFCKYPAETGVGEYGNTAIYVSDPKGNTNNENKYLKRRKRSEDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1J8</accession>
    <name>A0AAD5U1J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Monothiol glutaredoxin-5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GRX5</name>
        <name evidence="9" type="ORF">HK099_003660</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000241">
        <property type="protein sequence ID" value="KAJ3221252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1J8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019357">
        <property type="entry name" value="SCOC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF16">
        <property type="entry name" value="GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10224">
        <property type="entry name" value="DUF2205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="8">
        <location>
            <begin position="145"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3221252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="28031" checksum="9C107C2036C8BE03" modified="2024-05-29" version="1">MEFDDELTKDPWASSVSSNAKVYSSPKLSPPQIPLTNFVEQNVSNSGKHSRKATENDPEKQSLINLITELQDMLIASLQKIDSAKEEYQKNLNENQILLKYINNLMEAAGTNQQQLFKPVQRRWTRLISEQVKSNIEKKIASSDVVVFMKGNKNEPRCGFSKTVVQILKLNDITKFSDFNVLEDEELRSGIKEYSSWPTIPQVYVKGEFIGGCDILIDMHKNGELEKLFIDKGILVESTETEEKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1W8</accession>
    <name>A0AAD5U1W8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000633">
        <property type="protein sequence ID" value="KAJ3214300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1W8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="167" mass="16980" checksum="C03D1FBA22CA0290" modified="2024-05-29" version="1">MSDDLCVSTSLTLAPPFLAACGLKEEEYEYNSITVNKFCTPGPCNAAWSKLFNAQKAACLVSEDNKHWTPESCCANKQACIDASSQNGSNEPTFTALIGTGLTDPVPTGSTTSVSATASAGSSATGGSASSTATSTAASGDAKSSAKALNKSIFSLAVIVVFSLFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U216</accession>
    <name>A0AAD5U216_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome biogenesis protein brx1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BRX1</name>
        <name evidence="7" type="ORF">HK099_003180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BRX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000212">
        <property type="protein sequence ID" value="KAJ3221728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U216"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026532">
        <property type="entry name" value="BRX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="101"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="366" mass="42235" checksum="E728F444677EB49C" modified="2024-05-29" version="1">MKYSEKKEESPRNTKKELIFADDGGGGGDSGDEGFDSEDEDDCSESEYDSNDEQKPEKSVNVSQMGKKSFLFNNTEINMIRKPASKGDTKSDKKNLIKNRQRMLILSSRGIIHRYRHLMNDLNLLMPHSKKESKLDTKSKLYVLNELAELNNCNNAIFFEVRKHQDLYLWLAKTPNGPSIKFHVQNVHTMDELKMTGNCLKGSRPILSFDNAFELALQDPNAREEYAHLPLIKELLIHAFATPKTSRKIKPFIDHVMLFSLCDGRIWYRNYQIIEKDSIANPKEKDISLVEIGPRFVLNVIRIFDGAFGGRTLFENQDFISPNSIRREQRLSKSDSYIKRTDQSKVRNERMKDASQLPEDPTDFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U239</accession>
    <name>A0AAD5U239_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002836</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000198">
        <property type="protein sequence ID" value="KAJ3221973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U239"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF53">
        <property type="entry name" value="TMEM14 PROTEIN HOMOLOG YJR085C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="219"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="47264" checksum="47EC55521FB9E4D2" modified="2024-05-29" version="1">MSHHIAYTMAGLISAGGLIGFAKKGSKASLIAGCAVGGLYATSGYLISENRDNGIELALSASVLLSSAFLPKAIRTQKVMPVFIATLGVLTTCYYGKKLYENIYGISNETADATALKEFEVDNIEDEIFKSLPRRNLKGGSHVNRASIYTLGEFNTSAYPDNYDYYDSSSSHTSKSNELKKINENPYIKSEHSDISSSEEDADGEEVEKYTFIESWKHNAKEKKNSRPQPEKNSTNMNRTFTINDGYTRNDNKINDQKSFKRSQSLNHINQHLMEPVSKESFKDSTVFGDNKSNVKTYATDSKFSVNSDIIRNRNANEFNDGVRYKRYDLTHNKTPILSKESAPNYSSHSLKNLDALIETLNMTADGSDFQENSSINYESAVPEIKYQEYSSKDVSKMFEAIVSELGQVWEIRLKTIEENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2G1</accession>
    <name>A0AAD5U2G1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000275">
        <property type="protein sequence ID" value="KAJ3220763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2G1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="346" mass="39270" checksum="5FA62E78F1D08A6E" modified="2024-05-29" version="1">MKRSKVVFVESRYKTQVKVSSKQPAANNVNSSNLGTQKASSSTTPTSKSKTVNKSLKSTKQLSTVTLKESSKLNATSVATISLKNSENFKATPVKESEKENINEENFATNKNEKNFLPLCSKSALASSSAKSPTVSKEDEIFISKVKLLQVHYLKLKLKKNLDEKIQKEILNLKKYISELLIKKKKKVSTLSLNLNKKKFLFNQVQKFDLIFSSGLLEENIEEDFTSSQTAAMFSLYEALFQLVKNFVFKFELIDVSVVDIALFRDTMYSAAVEIQKLLNASGIDEFMIFSVQFKQFLKVMEEKLGVIEDCLNVKEKLQHLNVIQENFNIEKYFSQRNSTIISELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Z6</accession>
    <name>A0AAD5U2Z6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM227 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000372">
        <property type="protein sequence ID" value="KAJ3218614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Z6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029417">
        <property type="entry name" value="FAM227"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33560:SF1">
        <property type="entry name" value="PROTEIN FAM227A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33560">
        <property type="entry name" value="PROTEIN FAM227B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14922">
        <property type="entry name" value="FWWh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="505" mass="58601" checksum="27BB1FB245957D21" modified="2024-05-29" version="1">MSLSSPINVEELLAELSNERSQPEYSGGAASYSSQYKDYNLELNEKFQGEGEDDEIWALSPNTWPHVYSELVSKVAISLVRLDDLRQHICQFTTKLRLDDGMNVTLAYEEEFANQRLEIKKKVLDNSLLDEVKAEHPDKTFLTGVKLNPLVEDSSRDIDASQLMNCINFPLMIESAKFPESIDETISLPNNLLPQNLLSETLQSKNLSPGIYRRWKRKITSKCSLNLTTFSFWYCLRQNWKRLTESSPQLILRNNVDMTKDEEEQFKFNLMCSISKCYVTLLKETSTGADKDDFFQSLNLFTEKLQKSLSESITELICGIKPYKNFKNWSMNKLIIESKELENQELEKQALDIIKSERQQEKPKIAKKIPSMVCGPNFLTQRILFDVYGNSPVVSHYLRNISGSKIERKRLTIHRKEVLKDYLEDENLVTYKSLVAESLKNSKKLLKKYTQREAEISRERNKIIMEQNLEARRNEKIYKRQLSLKPLTKDTLSEQLVSKKVTIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U322</accession>
    <name>A0AAD5U322_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000258">
        <property type="protein sequence ID" value="KAJ3221003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U322"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="78" mass="8475" checksum="9778AC1DEE7C3917" modified="2024-05-29" version="1">MIGATIAQQQCSYVTTSTLHCTTPTGTPHAPTCLGRCQTFAYCKSCCDGLKRFCQTNPTATGCEEWEMQACVPDCRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U389</accession>
    <name>A0AAD5U389_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000246">
        <property type="protein sequence ID" value="KAJ3221180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U389"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="270" mass="30357" checksum="217126D588E32226" modified="2024-05-29" version="1">MISDISGSVKGALIFVENSWLLMFLHSIYVPYTFKKIAEAHPTSYAFRTLRNRNHFQLFFVNIILALGGGTMVSFLSGEPVSWIVNNKIIPTYAIGYYLVHSVPAVFQFLSSFAPFSDMILDCIVDGSMRAVIISANVDKIRRKISTNAYVAQLLLGVLSVTGGGIIYNVSFEDFKFSNDVYICAISNIFYIIGADENLKKIIYQICPIFFDYIYKTLGKPLGFSPKFLRDDAKALGAIIITTGFLLRFKEFKSVKTSNEKLKIHKEKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U394</accession>
    <name>A0AAD5U394_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DEAD-box ATP-dependent RNA helicase 3, chloroplastic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RH3</name>
        <name evidence="9" type="ORF">HK099_002111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000168">
        <property type="protein sequence ID" value="KAJ3222599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U394"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00637">
        <property type="entry name" value="7tm_classA_rhodopsin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="8">
        <location>
            <begin position="35"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="462" mass="52336" checksum="EF5052EF70B83A4A" modified="2024-05-29" version="1">MSLSEISGFIPYNTAYPQKQVALIYGLLYVVGLIANFIIVVASFIEFSSLTSPRLLLLSLCLSDVIFSLVVSSTNLYNYSQGGFAVGQLGCKVFAYFSIFSCGSSLLSCLGLTYDRYSLIVKEQNLNRARAIKYIIYVWIFVTLLASLPFLTFSSDYVYALEPALTTCIVAWESKKPLALGFTIICFIVIGLPLIFIGYAYSKVYIKVRKHAKSLSEVFSSNKKYSGGALDFSSNSSLEAQQACSHAKKAKSLGKRVKLNVEEEHHEDIFKLSRKVTWDYENYKDNFKKMEEGDLAIFIVYLVDSKWEELLTEYENKSGLKNTLLNVDGDVISEEVDIRKEFKKFSFEGNYYRPVGTVGVFLNSSEYIEYGLSEDAFANKKLKIASPGLLVVFSCFQGNKFGSRSVDFAEFYIKNVKNFEISALCTETDNVQNMRMYQNKNYIRICELKLDWGMATFFKKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3D5</accession>
    <name>A0AAD5U3D5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_001564</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000145">
        <property type="protein sequence ID" value="KAJ3223083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3D5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="580"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="633"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="719"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="819"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="845"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="66"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="329"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="598"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="911"/>
            <end position="1144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1162" mass="131172" checksum="AEF28C611B4CD954" modified="2024-05-29" version="1">MEPQISHPKQQIKQSPEENANFLSILTFGWITPLFKLGYKRPLQFEDLYPPTSILNTNFTVGNFEQYWNEAIAALIYRKSLRLSSAARTDFNSGKVINVVSTDCQRIQQMITTANNLWIAPIQIIATIVMMCYSIGYSALPGIAVILIVTPFNGALFNQVKKIRRTVAPITDRRVKLMGEVLAGIRLEKIESIRNLELKQIFKRALFFAAFGSIVFAIPIIGSSISFIVFSLQGPLDAAKIFPVLTWFQQLRFPLMILPNLLLSIAEYKIAINRVTSLLLTDEVEKQPDYVKDSDFAIQVTNGEFIWETSEIDKKAVPLKKLSKEKSDATIVDTSKEEKINIEDEPKKEINHLRNINFKIKHGSLVAIVGRVGSGKSSLLNALIGEMKKISGDVKISGKLSYAPQQAFIQNCSLKENILFGQEYQKDRYLKTISDCALERDLEILPDGDSTEIGEKAHVGKYLFETCIQENLKGKTRILVTHQLHFLSAADHIIYLSDGEIKEQGAYQELLENGGEFCNLMTSYGGVEESSTTSETETDVVIDEKKVLIEDKKEMLNFMNQIKTNELMSKEERNVGNVKFSIYLAWMKAAGGTVTMTFLGLILIFSTGMDLGQNFWLTLWSEKKFPFLSLNNYIIIFCAWGIANILTTFSTNLVFAVLSVRATRKLHYLASHRIFRSPVSFFDSTPLGRIMNRFSRDQDSVDNSLSDVLRMFCNTTLRAISYFFLIIYATPYFIIALIPLLCIYYVMQKVYRATSRELKRLDSIMRSPFYSHFGESLQGIATIRAYKEQSRFIAVLDERLNNTNSPYYLLVTSSQWLSVRLQLIGAFLVFFASLCGVLSRYTISAAVFGLAISYALQVTQTLFWCVNQFVNTEIAMNAVERIDYYGTKIEVEADFHKNTPAPPNWPRTGLIKFENVDVRYKPELPLVLKNVTFSIEDKEKIAIVGRTGSGKSTLMNSLFRIMEASSGKIIIDGIDISQIGLLELRKGLSIIPQDPILFSGTFRTNLDPFNEHDENQLWDCLARANLKEKVIESGGLDSVVQEGGDNLSVGQKQLICLARSMLKRPRILVMDEATSNVDYETDTFIQKALREDFKDATILTIAHRLNTIIDYDKVLVFEAGELVEIGSPSELLEKPSGIFLGMVEETGSVNAELLKNTVFDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3I6</accession>
    <name>A0AAD5U3I6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acyl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003253</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000216">
        <property type="protein sequence ID" value="KAJ3221662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3I6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF13">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="10">
        <location>
            <begin position="55"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="9">
        <location>
            <begin position="141"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="8">
        <location>
            <begin position="258"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="48931" checksum="D31BD437FD533887" modified="2024-05-29" version="1">MFVFSEKFLNLKQILTEFVELECIPAEKTFFLQMGKVGTPERWRVSLMIIPEVLEELKAKAKTLGLWNLFLAKEYGQYGAGLTNLEYAVLCETLGKSFIAPEACNCSAPDTGNMEVLAKYGNEAQKEKWLKPLLDGKIRSAFAMTEPRVASSDATNIETYITKDPKNPDYYLISGRKWWISGAGDPRCKIYLLMGKNDANNKDKHRQQSVIIIPADTPGITVLRPLTVFGYDDAPHGHCEILFENVRVHKENMILGEGRGFEIVQGRLGPGRIHHCMRQIGFAERALEYHILRVTDSSRKTFGKFLFQHGDVATTIAQSRMEIEGARMLVLAAASQIDKGGAKSAMKQIAMAKVICPNMTLRVIDRSIQAHGGAGVSQDFPLAYMYAGSRTLRIADGPDEVHMMQIARSELKKAKDLSSHYEKQQKIAADFKVKHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3I9</accession>
    <name>A0AAD5U3I9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000152">
        <property type="protein sequence ID" value="KAJ3222927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3I9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="31566" checksum="90038FFCC8A8AE11" modified="2024-05-29" version="1">MQRKLKKIFSKNSIANEEPATTLEGNLTDLLKVEQNQLDYIDSLLEDNLNLTYENIGALRSVTQSKSNYEFNSEESNNDYIGQRSKSVPIDLNNEIKDNVSSSYKSTYIMIRDRNDKIQQSNSTNTNSVTRNLSNAKIMPNLSQNRTNPVMTNVSQNSQNYSATADVRRYQKLENNTRPRQSINGMNVNADNHMIVSNSRNEHFSSYITPHQETPTQRQQFSPPLLENPFSDMYSIESLSSLPRGSDIQTQEFAVEIHPPSYDDIIGFNPPQYIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3L8</accession>
    <name>A0AAD5U3L8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003182</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000212">
        <property type="protein sequence ID" value="KAJ3221730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3L8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044043">
        <property type="entry name" value="VanA_C_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF32">
        <property type="entry name" value="CHOLESTEROL 7-DESATURASE NVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19112">
        <property type="entry name" value="VanA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Rieske" evidence="10">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="319" mass="36839" checksum="1BFBB652F377F9F9" modified="2024-05-29" version="1">MINKGDAVVLYRDPLTNDPIALADKCAHRSVPLSAGKIMDGRLECLYHGWQYDAEGKCIHIPTILPEKKIPANAKVRKYSTFEVDNWIWIHPGTPEQVEKSPLPKFKFGWNEVKKDQLTGYLDLDIDHSLLCENFLDPAHINFTHTSTFGNRDNATAMNVLCKFYNDRIESFNSTPLKELPVKAIATFYPPSCVTLRFQDSANPNTRNDLNFYSIPTTKGNSRFIWIQRAKFHPPILEYIPGFNWFFDFTTRRFIKKVILEDYVMLKGQQEILAFGASAMNSPVSADLMIKVYRNWWRKAMKKKPWFSGYGDIEDIILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Q9</accession>
    <name>A0AAD5U3Q9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cilia- and flagella-associated protein 251</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">WDR66</name>
        <name evidence="8" type="ORF">HK099_001470</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000141">
        <property type="protein sequence ID" value="KAJ3223168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Q9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF13">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="520"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="877"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="878"/>
            <end position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1242" mass="138603" checksum="F60EE94ECF203221" modified="2024-05-29" version="1">MSAVDLNSVPDEKLGKTENLPNALDQIWSYGMTSNSFGSVHNISDSYRKVLILMEISHSYFILKGIFYASANTGIIFEHQTGKQHLLQGHCNAITATTVTSNKRWLVTADTGVNCMLIVWDTLPGLTTPVTTKKEGSSVALSTSASLNPLPIKTLFDPHPGGVLACVFTADNKYLITLGSNEPQTLSIWDWTQESDENVCTCTIQGSLQVINTLDLILVSIEINPRNEGELMTTGPDAVNFFVWSKENGIKQHIPTLNSKDFKNNELEFTYSIFLPEVDEAISGTKDGDVVVWANKSLNNLSQTLETGKRATIKCVKLHTGAINFITSVSKKYILTGGEDGFVKVYDNHLRLLLWFERLKAGPIVSISFNNNNTSPDHDLPSQENILSDLDIPEFVVSTKHGKVLKLLKQNSTGSSVAAANLIQQALIKKSLSKGNSQNGTKTGAKAGLKKNKEEFTWNKEVNNGLNSEIEHTNIGSLGILHDGMISRELANTGNNENKTTSTKTTPNSASNTPSVKVLLEVQYEKITCLSCHPKKPVFITGGHSGLIQLWNYETKKLLGSRKFEEVKKVNKSKENGAKPNKEKKASEYNDIYESLSISCLAYSDSGSIIGVGFSNGFVKILDSRTLNDYYEILSTTNAPPQPPFPYPSKHEQKLNAEASKVKSYNGQKLSEAEKKNNLIQISKNAIIFLTFDVTEEYLAAGDDGFGVSIIHREPVVGELNTQEQSHNNSLDNTNLKKKSLNTSFSLSENNTDSFKKKEDIKMQWVLYGRNQAHFQNIVALMFIPKSDPSDEPVLISVSYDRNVAEYDVKNASISGGFALKSLNRIEQTAHPLAATFHPNFNREDEKVSASVPASAKAKLVEEKNINATTLNANSITETKDAQVKNEEENLNSQKLENEEALKKNRINTENFLLISSTDYKFKVYNATTKFCRKTVLGPLYGSPLTNICMIPPETHAKYFAFSTSEKVVGITKLPLDGNPNKFMGVIAHPNEVNETPTFDGEYLLTVGDATVNQWKIQKSSIEIQLSFQAAQSVLEPYLNLVDNTNLGKESPFYKEMEDYFYYAQLRSQGENSTTKRKILDRVQLDQVPYIFQAMGFYPTKIEIENLLNEVKFSLVEKNFNGLVNSVNFEDLIKLYVNHKPAKNYTEEELFRALDDCLEPGKKKNVVFGDEVGKVKVSKENEEITRDGLSALIELYGESFTEEEFKDSFAEILKSRRKYKGLMPDVFTKKEFVEKMLFLEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3T8</accession>
    <name>A0AAD5U3T8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit OST2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DAD1</name>
        <name evidence="9" type="ORF">HK099_003931</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000267">
        <property type="protein sequence ID" value="KAJ3220867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3T8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3220867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="91" mass="10025" checksum="761C20E1E1AB174C" modified="2024-05-29" version="1" fragment="single">AKPTPPPSKKSTVTSSKKEGFSELVSKGFENYQNETPQLLKILDSYLVFCVLTGVLQFLYMIIVGTYPYNAFLAGFICSVGSFVLTGENIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Y5</accession>
    <name>A0AAD5U3Y5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000288">
        <property type="protein sequence ID" value="KAJ3220599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Y5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052741">
        <property type="entry name" value="Mitochondrial_HTD2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152:SF1">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="15491" checksum="14A77E250D27777E" modified="2024-05-29" version="1">MSSELSSDGYLPTFAPPSPPFKKRMWVGSNLTFHKDLKSDLQIYNKELFVENVKFKESEKKDILFVEEKRLISDELGIAITDTRTIGYIHEKEKPVVYSALTYNSHLIHYDSDYARNVENYPAILGLIQLVMET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U427</accession>
    <name>A0AAD5U427_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005213</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000399">
        <property type="protein sequence ID" value="KAJ3218020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U427"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032469">
        <property type="term" value="P:endoplasmic reticulum calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012879">
        <property type="entry name" value="CCDC47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883">
        <property type="entry name" value="ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07946">
        <property type="entry name" value="CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041996992" description="SCP domain-containing protein" evidence="7">
        <location>
            <begin position="18"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="8">
        <location>
            <begin position="54"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="544"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3218020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="587" mass="67576" checksum="AA23A43E5C8CE7E7" modified="2024-05-29" version="1">MLLKISVLIALISNIQSVAVIEQTNVIGSPLIKSTAVEDSAIVEVFTTADTSPEASDEWETTHNNLRKQFGVPAVRQIPYLRDEAQIGANSMASTCDLNNIGNGYHAGMNRFWSTYKPAPADVVKNYFSGSKYWSNGDCRGNGNQKSSCMSFTAAAWKTTAYIGCASAQCKGSNNWVSMCVYNRPDNSEDSHDELEEEEKLESQKKLQQKDKKFSEFQTDLKNPLSNSKSNNFLEHFKGEDFFIEGTVVAFLVVYLALYLYGRFVNSVRANAWSDATRSIWEDQFSKIGVNDQMLLQDSPKDFLFFATGRNYVKDVYGYITCKPRHDLYSVLYDFFRSGYTHDFVTLNFNIDCECDNFIFALLPKLNSHLIVKSRYDLYEFTKAREVNSKFPKDQYQLYSDNQEFINHLFNDTQVLEVLWNSCGLDLDGNGSEYLSPLIESIIFTDQPKEKPEQPIDLEKPVSKVLQFKFRFPVIKQDSEKFKELMQKLTLLSLDVVDYIGQFGKLSFEIRDRVKRIRIAANSKIIKELEWIRKEELEKIKFKGKKEKQNAVSKLSPEEQQKFEEKERKKDSKKLEKKRLKKGKLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U461</accession>
    <name>A0AAD5U461_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="2">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">NDE1</name>
        <name evidence="12" type="ORF">HK099_002729</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000193">
        <property type="protein sequence ID" value="KAJ3222075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U461"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="10">
        <location>
            <begin position="15"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="11">
        <location>
            <begin position="341"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="421" mass="46910" checksum="35E14482A7F7C58E" modified="2024-05-29" version="1">MQPIRYITRKKTRECMFVEGDCIDIDPVGKTVVVEDNSELKGDVSKQTLKYDYLIVACGAENATFGIPGVREHSCFLKEIWDARKIRTKLMDCLETAAFPGQTESEVDRLLNMVVVGGGPTVSIEITEFVTNLPIFLNAQGVEYAAELHDFLVEDLTRWYPDMAGKIKITLIEATNNVLPMFSKQLIEYTEKTFAENKVTILNNTMVKEVKDKEITVLNKDKKLETIPYGLLVWATGNTARPVVSNLIKKLNPALQTQRRGLVVDEYLKVKGADDIYCLGDASATKFAPTAQVAAKQGKYLSDRFNRIGYLEADKDNMERSGVKFSDAVSLLPPFSFDNMGMLAYIGSDKAIADFPGGIQFGGMMTYYFWRSAYLSNLFSMRNSPLTSVEAKETKATAAVNLTIFVECFGIPLDAKVVAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U496</accession>
    <name>A0AAD5U496_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005037</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000379">
        <property type="protein sequence ID" value="KAJ3218464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U496"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000004">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF8">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="7">
        <location>
            <begin position="577"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3218464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="875" mass="98803" checksum="68E07B9AAF560404" modified="2024-05-29" version="1">MIMAVQLAQRPSVLFCQNVPQEPVLTSLQTENSNLNTSKPFLSSLLNSTPFATLFNPVAIDSVKTTERKRSSTTDLLLDNSNSDVSVTSATTNGNNNDAAISDSIGSLGLKMLNSLKFKTKSFMDLPSLWSSSDFSKDNTYSSTALPSSPMLHSGTANSSPINSVPTSPTSSRKLSNLRQSSTSCVEESDENGQELSLKYLTYPLLKIAVENFKNSLKETEANVEVKVMTDQDTDNPSLFVDRDKLNDSTFLINTLRSTFSSSEALNNSFMYPSKDSDKFDHTSNPFGIDIQAVRDSYDLILELSSHETVLMTFVNAQEILLAKLQLNLKRLQYGDPKMLRQLIILLENPLLQDKSYQESLLKKLCIVIGGLKSKSRAVLKSWLTAYDQDGLGRIVKIFQQYFDDHYYAGPNSDEALIASVKVLSLLYHANEASKPKLLKINCFYSDSLCRKLNFKDEYKIWKRTQQPPKTGHIPRSHSMPNINGFPEFSYFNFPFLFDPVAKTRILHIDAMTQMSLEFEDAFVHQALVIHAHKFLQDSASVATIEQELERKTNPYLLLEVRRSKLVDDVLDQITRKQADLKKPLKVKFVGEEGQDAGGVQKEFFQNLIGYLMSPTYGMFVYDEDTRFVWINGASLESERQYELIGTVLGLALYNGVILGINFPMIVYKKLLDEEIDLEDLKQGFPVLGRGLQQLLDWDDGDVADVFFRSFEISYDVYGHVKTFPLVANGSDIPVTNENRKKFVKLYINHFVNESTKRQFSAFRRGFHKVCGGPALKMCRPEELELLICGTTTTNMDFKLLEEATKYEEFSPDDKLIVGFWKIVHEDFDLEMKKKLLNFVTSSDRVPLKGLGNLTFKIQKNGGDTDRLPTSAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4N1</accession>
    <name>A0AAD5U4N1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003663</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000241">
        <property type="protein sequence ID" value="KAJ3221255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4N1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19120">
        <property type="entry name" value="AKR_AKR3C2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044494">
        <property type="entry name" value="AKR3C2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="297" mass="33951" checksum="49642733A69E932C" modified="2024-05-29" version="1">MKKFTLNNGTQIPAIAFGIGTKFFRGQDQNHAPDDLDFKITEAVKTALKTGYTHLDNAEVYGNELEVGLALHDPNVKRSDLYITSKLLKNIKDPKNALNESLQRLNTSYLDLYLIHAPFFSEESHGISLEDAWKQLEGLVDAGVVKSIGVSNFRIRDLERILKICRIKPTVNQIEYHAYLQSRELVQFCKENQILVAAYGPLTPIFRKPDGPLGAVLEKLSKKYSVKPEIILLRWVYQQGILVVTTSSNPERQKEVLSYFQENKDKQEFALSTEDMDEISTVGATHNYRHFWKNEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4P5</accession>
    <name>A0AAD5U4P5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001940</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000160">
        <property type="protein sequence ID" value="KAJ3222772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042150659" description="ABC transporter domain-containing protein" evidence="9">
        <location>
            <begin position="22"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="701"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="734"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="814"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="842"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="363"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3222772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="871" mass="94287" checksum="1C0DC81BFCF42468" modified="2024-05-29" version="1">MMITYFGPLVTLFILQNFILSQIISNSTDVVSPTLNENNATIAVPTIPQTCPVCPNLFSCTDDLKCNAFGHCSGNKCTCQPGWTGEACLQLSCGSPNSEPHQRKAREGNSCEGQCEPGFVGENCNVCTQDDVCKAGAFGSKQICNKQTVVWKDSANMYCEIDEITLNGFFPGKKNSYFARNITDGSTRASLFYDGVEQFNCRTSGCTQELDFEGKVTWKCEKSECRCIEGSEMCTGAGGILGKIFKNLEDSGASIAFPTEESADIVAKKNPAIFFLTHPDFVALLPNGVKLGPCRVGECVDPADRIYLDKSKKPSEFTTQAIASISFGCAVFLLCIIGFAFAFKKQHKLRKIPVPATRTGVSLSFNNISYSVNEKDILQGISGMASSGRLMAILGPSGAGKSTFLDILAGKNKSGTISGDILVNGKTMPANKLRSICGFVDQEDILISTLTVKETLQFSANLRLPEAYTKAEKEKIVDETLETLGLSHIANSYIGGNGVRGISGGEKRRVSIGVELVTSPSILFLDEPTSGLDSYNAMMVIKTLHDLANANGGKTIIFTIHQPRSDVYKLFDDVLILAKGSVMYIGEGKEAASSVAASGAPCPSDYNIADHLLDLAMAHSLADQPIGGVGIAMEPYVNVGGLYNRKKKSIENITDISFDSNPTSMDLHNNKHAGEHFTVSFLTQFQQLSIRSARVLYRQKTLLLAHVGVALLLGIIIGGFYFRITNTFAGFQNHLGSALIILALIGFSSISAIGVFTTERLIFLRERSNGFYGAFPFFLTKIIFDVVPLRILPAIVMGTVSFYMIQLNGDYFKFILPLILFSAQCGMYSLALASAIKDFGTATLVTSILQLFQMLMAGFLINACKKSIILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U585</accession>
    <name>A0AAD5U585_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HORMA domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HORMAD1</name>
        <name evidence="7" type="ORF">HK099_001185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000131">
        <property type="protein sequence ID" value="KAJ3223412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U585"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051294">
        <property type="entry name" value="HORMA_MeioticProgression"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225">
        <property type="entry name" value="HORMA DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225:SF7">
        <property type="entry name" value="MEIOSIS-SPECIFIC PROTEIN HOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="328" mass="37384" checksum="7BE0D2C52708858F" modified="2024-05-29" version="1">MKLYYYEENTPANYEPPCFSAGDGDKLFYFGRDAETITLGSLKTGFHSVDLCVETAANISCDKDDENIKDLNISQDTVLLNSGQIVEATTFKSSSYSAQQSESTQELVNLLCEKEHRLNVMEGVEQEIIVLQEESKSIEKNVCCPCEVNNQVDHDMIHCSSCNTWGHLFCFGFKNSEDFRIPEKHNCYNCLNTLYAADKENNNQKKHSCFDLKKQSDISKYRRAIGYIWVEGFESTEKFCGTSLNATQKLFNNLVNDGFLALSKKIRTKGKVYYVPKNKKTRELYEFYFSSKSNCFVNSANEKKMKQVKSSSTEKKKVSVVSTKLRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5F2</accession>
    <name>A0AAD5U5F2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021861">
        <property type="entry name" value="THO_THOC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265:SF0">
        <property type="entry name" value="HPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13265">
        <property type="entry name" value="THO COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11957">
        <property type="entry name" value="efThoc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="838"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="613"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="839"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1536" mass="178683" checksum="EC5A17BB531BACD5" modified="2024-05-29" version="1">MNREQKYYTVNRSRLPKPTTSQNSNIYKIGRLPPVDTSYNFEIHRNDNCQRSLLNSPGKVKNFFNDNRNRPLGIDNPTIGQLFNKQVIVPSIGKKQLNQSDNIIKVVPVKYSHNENLNQFPSDSKHDLRSVFVEPTSTGQYTINSHRNKYNSIPQLQNSQENNEIRINCQQHLYRHPETSNFQTQYPHIMVESENQHFYSPKVKHVMVDTQKNYPQTNQILVESQNDNSYIQKTRHIQVETKNSSHRPKTFDNCRNSTQRPITRQILLESQNHPGYPSHQQIILESQLQRPQTRQIILEPQNPQTHIRIDTQNTLHKPGSRLIKVENQNQTQHYIPNSSKVKVELQNNKSAKQFKVKSQHQCNRQYTREVEVKASLTRPHTQEIQVKTEMQQNPPTFEINYKSQPVNKSRTRQITVEMENQNQHFSEGREYNLESNKRNFPVEPNLENKEQLLVQEIGRPHCKSASVSISNVDRNPPRKRSVSFATDKSCQINFSEFNQRPKTSSLPVFVTENQKRDRIIENCTPHFSHDRKNSNHINISFELPPHLFNKSILPESPPLIPSDQSRMPRIDDNHFTQNPPVIQLVLPSENMQKNKKENIFVLNKVSSESSCSSEENRKVVEMIELNLKKAEKERKSKKKKKLKKTKKMAKAYLNKRLLNRGYSMDSTSSNTTASTDFFSMSNGAFFNNSSTEDEFEYFYKNKRYRSCNCKKKKKVNDSIIIVKNDNGNKENIVYLEKDDMMPKQKFEIKQDNNNYNDYAVATQKPPLESINKTLGEYSFSFNNGINDQKNKEKSSILKSVNRNRSESNQPVTHTVFDVQEVQNNFQRCIPESTKKISKFDSTTSSSSTSSSSTSSASSSNSESVNLINKKIDQILNELNKEDFENWEDILQVTKKQSLNTIIDTFDPSLVSDIISNCLKSKLFALAKISNTEEKSFFYKLYKLLDVSLWCVINYENVDQTLTFSLIADSIDILTIKGGEKIFDYIDFRLEKLTDNKKKMEANKGKGLNLLRLCNEMVKRLSKAGEALFCGVNHLGDFNLDNVTFFEREKVEDNMETGETIKKDKPLEDKKFFNIFWDLQQYYSNPMKLLTESNDIFKSFQSNLEIVLSRFEKLNPKKDEKTRNYDDYRRRKDEQMVLENNSSLNKQHFFPKYLTGANLLFNHELEDPFFRKQILVQILIILQFLLFSTENEKVKLQKFFEENSVIQNKKSKFYSSFTFSSDQASWLSKIRRDFMVTLENIPPFGKQFQRTLTTGIEKKFNHYILFYLIVISHEANWIRWKNLGAKPFEKESIKVEKGIKRFKKKTTKAIQREGEPAYMGTAELTTIWADVPDMNSALMDMADSIAESVKPLDKYLKILDLQLDSNLNPEEGQEEEYLCYNEDKTYDWCAYRIARSSDFKLFASVPNTPGPVKPVGSKTLLGKWREENRIREEKKNDVALIEKKIEEGEIENGELIEDDEGFSIEKKENFIEVIDLTDEPTTVMVRTLLDAVYVSAKQFQTGLKFPKVALAEWLTRWPAKPLFSECTGSNPVGDDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5X4</accession>
    <name>A0AAD5U5X4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Pyruvate kinase</fullName>
            <ecNumber evidence="6 17">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">PYK1</name>
        <name evidence="22" type="ORF">HK099_006523</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 17">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="6 17"/>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5X4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000025">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14 17" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 17 22" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 22" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="21">
        <location>
            <begin position="15"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="21">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="19">
        <location>
            <begin position="140"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="18">
        <location>
            <begin position="455"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="20">
        <location>
            <begin position="805"/>
            <end position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3225583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="947" mass="105886" checksum="D75B26CA1460D554" modified="2024-05-29" version="1">MHLIALGHKVILITHQYGNRQGVRYLTSGLKVYYLPHFLVWDQVSFPTVRETVAFSSMCHEAILHARTLGLKAIFTDHSLFGFEDLSSILTNKLLKFTLSDINHVICVSHTSRENTVLRASLNPYHVSVIPNSIVSADFQPDTNKRNKNFITIVVTSRLVYRKGIDLLIDVIPRVCKNFDNVRFFIVGDGPKMVDLQQMREYYVLQDKVKLFGSVQNNKIRDILVEGDIFLNTSLTEAFCIAIIEAASCGLLVVSTKVGGIPEVLPSDMIIFSDPDGISILEALKNAIQILNCGDIDSEHNHTRVKLMYSWDNVALRTAQVYKNVIDMPDISIADRFFLFYTTGSWAGKLSVLIVAFNYIILKLLEIFFPVDEIELSLDFKIDQVKKIFRLNMSNNPNLGNLMSSKNFSSYDKLCASYAQNSDIPLLQRAYLDWKTEVIIKEEDLFVSRVYKSYVRLNFSHGTHEYHGSVIKNVRESFLHQKGRPVAIALDTKGPEIRTGMMLNDGFAFKTGHKLIFTTEEKYKDNGNPEKVYIDYKNLTKVMSPGKFIYVDDGTLTFKVVKVNEDNVEVESMNSGTFLSKKGVNLPGTNVDLPAVSEKDKLDLKFAVEHGVDMIFASFIRQAEDIHTIRLLLGEAGRNGSIKIISKIENHQGLDNFDEILKASDGIMVARGDLGTEIPSWKVFIAQKSMIAKCNIAGKPVICATQMQSMTSCPKPTRAEASDVANAVLDGADCVMLSYFQSKIIIKITNLKFFTVRAETASGQYPLESVSTMARICLEAEAVNTYYPHFNEIRSLTPKPLFTSETIAVATVNASLEEEAKVIVVLSQSGTTARLIAKYRPKAAIVVVTRDATVARQSHLFRGTYPMVYKEKQNIDTDELPPSPVIGAMHWKAAADWQIDVDARIDFGITEAKKLGVICGGETFIAVQGWKPGSGQTNCLRILMTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U694</accession>
    <name>A0AAD5U694_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">INTS8 TPR repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000152">
        <property type="protein sequence ID" value="KAJ3222928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U694"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057980">
        <property type="entry name" value="TPR_INTS8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25756">
        <property type="entry name" value="TPR_INTS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTS8 TPR repeats" evidence="1">
        <location>
            <begin position="697"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="848" mass="97876" checksum="62B3BC21B5EB0E5B" modified="2024-05-29" version="1">MEAEYHNYEKEITKISYNPISISDYILNPQKLEEVSAIQQKEVINLLFERGDKNRLNDPYINLLSSFCSNWDLDKIEEYFWDNSKIPQLLIAIAKFKVKNSENKPDFINFWRHHIRICSKLCNECNKSAIYYLNNALDEYSMGDIYGSSNVDVESLKEIAFDLANYYFCLKDYTNADKYLKTAKEFNFDSERKLERLTAILLQDQKPISSNLPIQIQVSKIVTSKKFMEIIPILAVDVESIKVGSIVRNNLARIAFKSGQIEAAGLIWVSLAIAFVECNAAKNLTLKYTAKFKLEDENKTNHSAKSKLEEKEKLIYININKFLEKICLFFDNVEIWNEIYLIGDLSCRKGVELYKTKVSKPKIPESALPIYDAHQFKQNLLTSITSNDSEVLLQEINATLISPTVSIPFLSAQANYYYQKVGIIPSPFSFHINLKGEYDKSTLIFDCVTKIFKFSGLPGRDEIKVLAFQVAFSQALDTMMKEVLEKKKNYNIPMDRLIGYFDISNTLYNYKKVLTFLLIDFLKNPTNSTGKSLLLSRISKGQNSLGESSHLHIHFLSACLATAVITMDKFAEKLLIPFGDVYVQHKQIDTNFDFKLFHSISVILANFLGDSNLKNVEEIQDAFIDILINLEDFRLSWFTGGILAACLSLNLSKSEQIDHANFGIMSQIFLNWPADPNQPIEKFNQKKKTLLIKFLIKLYTKILQKLNSDKLDMVQNTLYTVKVLNCLGDLNYLNYDFRASLKNYFSVISLESNFFCEGNMREYFAAKSRYSSRIIDCCVKLEDFFSASVFLQFMEKVEYQEIFNFIKSLMDTKDDQFLETRIVYYFDVSVLEFLTKKKQYQNAGKIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6C1</accession>
    <name>A0AAD5U6C1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glucose receptor Git3-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008201</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6C1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023041">
        <property type="entry name" value="Glucose_rcpt_Git3-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11710">
        <property type="entry name" value="Git3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose receptor Git3-like N-terminal" evidence="6">
        <location>
            <begin position="3"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="44913" checksum="75AC65B70E50B9CD" modified="2024-05-29" version="1">MLIGIFILYFTKNLKKGYFTGRIKLIISLLIAGCINSGNNAISTAAITIYETPLSGSSCIANGFIGQWTVQAGDFSTLSIALVTSYVSLHKSPNYALNVVEKWLSTMLFTIWGTSLSTAVTGHFVVGYKWTGTWCWFSATPLPLSTYVRYFLTHGPRIVIFVLIIVAYTYLYCFFRVKLKFAGLKKDHSVNRTVNQILIYPVFYVLLWSGGMANRFLDATTGSTEVTRFLQSFTQLIPFADSMLFIASNFVKMYLNKFPHLKKKVTEEVAEISVANNTCIKSSDIHFDDEKGDPPVGWIQTSEDRPHVMNLKLALEGIGEDGFSLDGPSENVEFDDLELSSKSNSHFEEKNFIFGCGLPKIQVEDFTDHNDFNTKNNLFDLNKRSVTPLPRTSMPPMVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6D0</accession>
    <name>A0AAD5U6D0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">YABBY protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YABBY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000165">
        <property type="protein sequence ID" value="KAJ3222646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6D0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006780">
        <property type="entry name" value="YABBY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056775">
        <property type="entry name" value="YABBY_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31675">
        <property type="entry name" value="PROTEIN YABBY 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04690">
        <property type="entry name" value="YABBY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="YABBY protein C-terminal" evidence="6">
        <location>
            <begin position="36"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="82" mass="8954" checksum="09BEF94F84B67D6D" modified="2024-05-29" version="1">MASEEEVEAPKGRGRPKMDPSEKKTPAAKKAGAGTKSKSPYNVFLKTEIPKLKEENASLSHREAFKLAAKNWATSDANPKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6H0</accession>
    <name>A0AAD5U6H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007939</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000082">
        <property type="protein sequence ID" value="KAJ3224754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6H0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002344">
        <property type="entry name" value="Lupus_La"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF140">
        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00302">
        <property type="entry name" value="LUPUSLA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="79"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3224754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="31103" checksum="EBD9F03142F27E30" modified="2024-05-29" version="1">MSKKVQEYCLFLLGEIAKNENGFVSLDTLLSFNRLKSISEDKDLIKEALKDSEFLEVDDEKNMVKRTTQIQKTILNWNHGVYVSGFPEDLKDIVGTAKEIFNQFGNVNFVKILRNKDKLFKGDVLIDFNAEEPAAKALEKKTLEYNGSTLKIIKKNTFYEEIKNKEYGTRKKDRYEEFPQLSYLPKLVVNEQEIKNKFKANKNKSKGDKKSVKKASEKVEKKDQKVDENEKKKIEENGKAAQKQDLTGKRKAEETNDSEELKKVKVGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6I7</accession>
    <name>A0AAD5U6I7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Dynein heavy chain 2, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">DNAH2_2</name>
        <name evidence="16" type="ORF">HK099_007863</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000080">
        <property type="protein sequence ID" value="KAJ3224819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000002">
        <property type="entry name" value="Dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000006">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056759">
        <property type="entry name" value="DYH2-5-8_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL HEAVY CHAIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25007">
        <property type="entry name" value="DYH2-5-8_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain tail" evidence="13">
        <location>
            <begin position="281"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein axonemal heavy chain 2/5/8 coiled-coil" evidence="15">
        <location>
            <begin position="1164"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain linker" evidence="14">
        <location>
            <begin position="1352"/>
            <end position="1702"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1630"/>
            <end position="1657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF25007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3224819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1705" mass="196715" checksum="083F23C75F818A5F" modified="2024-05-29" version="1">MLEADPNINEGKAVEVNITIAGDQNAEEKIEDQKAAYPKEPKVPVSRMVSMSNLQSRGSSTIIPAAKGGGLIEDPVFEKIENKEDEISLTESQINLNLESSRMESTLNMLSKHLSILITLSDFSLDMWTAAHNAAVKDFFVGSGRRRLLAFVEVNSAGNKEFFIQSILPSKNVQQLMYFIVDNTHEFVESIADFEKKVQFGTIEGSLMESLLRLMQGVYVPFFVENQNWPDSVKKEFVSQLHKFMAVLTDTTYQGVGHTVLYVPNEDLSVIDKAAKTKDLVQRLESLLVHWTRQIKEVVNNQHTSETTENSGPLEEIQFWRSRCDDLSGISQQINRQEVQQIIFVLEVAKSSYLEQFLRLSNLIQDGMLQAQDNLRFLSTLNSSCEELSQSEPKNIPSILPKLLNCVRIIWANSKYYDTKERLTSLLRKVSNEIIRRCCVKISLDEIFHGDVQMSMISLQDSINCGESWKSIYKKTCQHVFKYTKVSASIQQKVSWDFDQSSIFAQIDAFVQRCRDLLEVCEGQIQFARKISNGEKATVPFFGGSKGPEIAKSLEDIEVAFEKNLSILWNMRKHILDVKATRWHDDYNNFKHGVKDLEIMMQNVIVSAFEGATSVENSVELLEIFHHLAKREAIKRTVEKKTTDVYMLFLQELNAVKVEFEIHRKAPDILRFHPDFAGSAYWARSLHRRIAHSYSILDAAYYLPQTGMSEECKSQFQSLVAALEDYIGKTHTEWIASIDKDLALKLESKLMARKAQNLLEIKFDKDILRVFSEIHYWQKLKMDIPFHIQEIFSKREELRVLRENVLLVVRDYNSILETLAAEGESKLFKERIKFLDRKMNPGLLSLTWGSKGITEYFVKECRRHSHDVQNIVSEFVESNATIQRTMKIMSETILWKIENKKVYDLEELEKAQAEYRIIAQDKLQTSYENIKNILCSMFEGFKNDGREVYSHWVKYVDKIDKGVEEALRMTMKRSLQEISKAINGEGKNRDGAVEVHPLFKVNVVLEMQKVDLNPTLQKLEEVVNKVSRDMISIIKVIPRLSELLTPESNKFSTKIYDLVSSEEDIMKIFVSIQTGMTNNAVKCQAYIRNWDSYREIWEINKDAFIRRYAKLKPALSTFDADINRYNEVANNTQKEETLTNINFIRLDCSPLKHTLVSHCSAWQNKLTTLLNTNAINDLKNLHDMFTNKTAKLKTPPKDLDQLCESLSLLQQLQSDSASIEAQFGPINEQYQILEKYEVPVKEDEKVLLEALQPAWQNFKISLEESEKELQDYKFKFKADILSAVDEFTRSVVLIKEDFTSKGPFTAEFGVDRALKSIEDYRASLDAAIISEKNLKKGLAVFKIDQAPNKDIETLTNQLENLNQIWILTQEWNVIWESWKTQTFLSLVDSEMEDTVQKFLKRIAKMGKDVRDKDIFHVVKDRINQTKRSIPLLLELKNPAMRDRHWSKLMEEIGKTFDPKSEDFTLEKIFDLGLDQYGESINTVSGAATKELSIEQGLTEIETAWNAMDLDIVPYKEDKGYFKLKSSDAIFELLENNQVALSAMKTSKFFLAFEKQVDHWERTLSKIVEVVEILLTVQRQWMYLENIFVGAEDIRKQLPKESAVFDGVNVTWKSIMVKMTEDKNALRATHVNKLNETLNDMNLKLEKVQKSLDMYLETKRMSFPRFYFLSNDDLLEILGQAKDPNAVQSHLKKCFDNIYKLGMRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6K8</accession>
    <name>A0AAD5U6K8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001577</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000146">
        <property type="protein sequence ID" value="KAJ3223050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6K8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038:SF1">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="24"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="415" mass="48328" checksum="3A4A10F8D85DAA81" modified="2024-05-29" version="1">MLLRSKPQVRFFQIFGKILNNRNKQLYVGKLPNSLNSADLEDMFSKYGRLVQVELKPGGFGFVEFEDPRDAEDAIYALDNRLIEGQRILVEFSKASKTLQTRTQNDGDENYSSHNNPSHLQNSQGNCFLCGSAEHWAKDCPDNKEKGADIRSGKCFSCGEVGHLSRYCQVGKEKLGDSKDGQKIIPNSISAGACCFNCRQPGHIAKYCREGCFRGDRGRAINRSSEHYRRFDYSRSRSRSPFHSRARERYISPVRGQRSISPFNDSGYGRKSPHNERRISPPPFRNTGDRSPVYNRHRSPYYDRRSPLLARGRSPLYERTRTPLYDRSRSPMFERPTRSPFYGRSRSPVYERRRSPLYDRPRSPLYDRPRSPIFSRPRSPFFDKPVSPLFEKRSLRDMSYPRDYSKLREDFSRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Q2</accession>
    <name>A0AAD5U6Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000072">
        <property type="protein sequence ID" value="KAJ3225070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Q2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="706" mass="79529" checksum="BD3EB770D03EF1AA" modified="2024-05-29" version="1">MSNNNLEDMLNRLEAIKPARPINNDYIFVEQNFQTTPSQHQNSELEKLLNLACFHNSKQKEKKEESVNINTIPVSTASKKFCEMLKEFEKFNKVDLELELNNLNVNFQNEFNDEMFLNLLKNLMVKQDELESYFYRKRLKLIESQEKEDEELYIEEIVNGRNLERENEREYEKVNDLLQFDLNFQNEIMKLIQWQQKTLYNFGFLAFKPTNEENLIQIQHSILIKLISHLKELKYSNSNSKPNTKKVSSPSRSQTLKTKSMNEPKKSSTTSNEDNTETSKGDAEEVSHKSSTNRLKESNTNTNENNSATSRPDNAVEEVSSKKSPNPAPTTPTSSDNANDPEDTSNENLPNSAPVSTTGNSAEISSRSSQNAVTTTKPETGEDTSNPNSLNSLTSKVEETFKSTLVPSSEISTHMTTNKFSTTDEVTSSSSDDLSTIKTTRTTDPDNISFTKTKLDTQTITTFSRPVSSPVTVIKVDTKVITYKDAKNDVTKTKIIKYETRIENSHTRIITIDSSKNDSLRIQSSYSVIPASETADLSTQLKKPSGSLTSSQTVAISLTAIGIVLAIIGVLNIRNFTKPRRRRGEGGVTLQMSESDNPSCGNESPYRSQSQRHTLDLSNLNIYRSNQYDTLPNRNHSLVYCHSTLPLTDYSNHSPYSTMVRFNPTNEYVSDDGETHSAPIQSTYEIDDTSVDTDVPLNQGSLQVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7D6</accession>
    <name>A0AAD5U7D6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integrator complex subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">INTS7</name>
        <name evidence="3" type="ORF">HK099_002933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Integrator subunit 7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7D6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033060">
        <property type="entry name" value="INTS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056516">
        <property type="entry name" value="INTS7_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13322">
        <property type="entry name" value="C1ORF73 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13322:SF2">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24436">
        <property type="entry name" value="INTS7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrator complex subunit 7 N-terminal" evidence="2">
        <location>
            <begin position="14"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="874" mass="101868" checksum="ADD529D82E428B23" modified="2024-05-29" version="1">MISDEKLEKGLQHLLEFDREFRSIKVEDSNMAVLKFITFFEEYKDIKTLINSAFSKLAEYWRTSNNFTRESLLIVFKNVLSHFKNTTNYAEQLRSVGLVLESNDPVARSLTLRLLGYLHEISSDRIEIYHLIHEYLDSKYDFEVKAAIFITNKFCSKSLTFSIDVSEKLINLINDPKINNYNRLSLVNIFKNMTFNPSIANQSYNALIKFYKKTQFSQDYYTVDLAIVILKTTTELAKYCIFHEQDHVELLFSILTKSWKSELLCFGALNCLQMLSNKTSLFSESNFLILLNIFENTNSALNKNSAITLLNLLLSDKLYKFKLKSFFLLKKKEFKDYEANFFKLLTNEILQSNDLKIFFTIIDIILKFFEEKEKYEEVLQQLLKSIVSNSCAEKIDLLVSRYISLSKYQPDVTASYIKNLISELSKVSPDAILPETIIKVLNHRLFQFQSDSEFLNVAENMTQFGLKHGVKPSVYAFICLNSRSALTLTSFSKILMEKIQDSPSYYWDLYKIAEKLICEGNFQLSNSLFVTCLDQTETECSYFWLSTLIQISAIESSINQLENLNNIESCLQDLILEYDYVILNLQAFKPQIATRGNVQVKPKDAIILQLEKQQLESSFQLQFSKIRKEFLFFFKVSFSFFNTIISEEDFLLFFKRVEFLITEIEKLSSSFLFMGSQSNRVLDNLIISLLILLQILQKFKGINNEKIAIKLMDMFPSKKSVKDFKESLSKLNQNKLFELSSSLVEENINLEKTLFELLKIQFSIPRYFFVIEQDHYFKLNISSSTNQSRFDTKIILNCKCSLHCKIKIKRVFKVEVKVIDEEGVVNQIKTYNLDKNCTFETIIMLDKGNKKISFGLLDDSASRIIYTQNYFVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7R1</accession>
    <name>A0AAD5U7R1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_001692</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000150">
        <property type="protein sequence ID" value="KAJ3222974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7R1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000060">
        <property type="entry name" value="Sensor protein FixL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052162">
        <property type="entry name" value="Sensor_kinase/Photoreceptor"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304:SF1">
        <property type="entry name" value="PAC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304">
        <property type="entry name" value="PHYTOCHROME-LIKE PROTEIN CPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="710"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="830"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="902"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="952"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="1026"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="551"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="233"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="334"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="551"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="568"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="595"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1184" mass="134691" checksum="19679E79E17F8E7E" modified="2024-05-29" version="1">MDSQTSNSDTANNLSVNPIDKVAEAINAATNPVESLAAAVNINIKSTEQLEQSIENSQKSVGQIGSRNIKISSNGAKPTFLIDPHQQTLTEDTNTSKKINADKENNSTLSSSNIALILENETIKNEVSGVNQKETTLNDCADSKVRARKTSTTAVKKSTATAEPVNTKNSAAVETLTSEESIKKSETIQKTTLPNPVAEEIVQTVVLNDSYSDDKEKRLADFVEKLGSGDGEKNEQKKKIDSLVKDLQAESQKVEEQILAGQNEIFHKNEEAFFRVEDEHETLSLKILHLEDLKALKAVKEQCVQDVVKRKEAKRFQRQQQREVKSLHNKTHEQEMAYKKIEEVKKKLAEHRERTEKLVDHIEERHLKQVKQFNACEARRIADQKLLVEIKCTHLSEEQKIAAVKENLSKISHQKALDKKKLDQIREQQRRELRHFKDRIDLETRMMEEFSNMHSQHAAEENEMINKHKNDYLTEKEKITATQVSIKVIKLQTENQIEITKLISLQKTQLRQLKRAQKNRQAKRFKHWSAIVQRDLTKKVGSGAQSLATSNFQSADGSQSSSVGSHSLPESKTLTRQGSEKNLKAVVPNKKLDLLGEEDEDETDESSLSLDTQHQKSEEKLQKMLSNLTELKKSQDEELDKLRRKIKEEQTAKEEEFQKLLTELDWQQDVNLKDLKKADEAEINEALLNQERELELERHIIGAEIKALMERKVLKNLLDTVVDGVISIDPRGYIQRFNSAAEKMFGYPSSYAIGKNIKELMPQHHRENHDDYLYKYLTTGVKKLIGLGKTLRGQRRDGTTFPIHISVTEVVDDGFHLFTAIVRDLTEMEAKEETKKAEDDCLPQMIWKTDPTGKAINLNKNFLNYSGVSEDKISTINVFSQELIHPEDFKRSSKVFSKALKDNKEFEVTRRIKGANGEFRWFLSRGTPMFDADNKIQFWCGSCTDIDKVENFKLELQQLPEAVPTIIWKVNTDGDVVFANKRLQDLTGVDYTKSPVNMFSTDIVHMDDADKSRSAFVQASKKKIFFETTRRLQGINGRYTWVLTMGSPVFNAEGDVAFFVGTCTDVSESKALQDEMLVLPESYPQMVWKSDAKGNVLFSNKKFTSYVGEENKVNIFSEAFVHSDDLRAGRDGLARALKEKGAFEIRRRLKSSEGSYKVHFTKATPALNNLGDVESWYGSDTVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U876</accession>
    <name>A0AAD5U876_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein SNF8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">VPS22</name>
        <name evidence="2" type="ORF">HK099_004302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U876"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000085">
        <property type="entry name" value="Vacuolar-sorting protein SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016689">
        <property type="entry name" value="ESCRT-2_cplx_Snf8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806">
        <property type="entry name" value="EAP30 SUBUNIT OF ELL COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806:SF0">
        <property type="entry name" value="VACUOLAR-SORTING PROTEIN SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="194" mass="21854" checksum="8232D49CA9778F4C" modified="2024-05-29" version="1">MRRGAGISGIQKKQQTKTNFNKVAKSIQDNQIQLLQTQLSQFQINLEKFAAKHKNDIKKDPVFRAHFQQMCSKIGVDPLASNKGFWAEFLGVGDFYYELAVQVIQVCLATKASNGGLIEINELRSSVEKMRGNHLQSISNDDIIRSIKTLSPLVGKGCYTLIDVGDKTLIQSLPREFNMDYLKCLEVAEVQKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U993</accession>
    <name>A0AAD5U993_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000067">
        <property type="protein sequence ID" value="KAJ3225235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U993"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070813">
        <property type="term" value="P:hydrogen sulfide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051682">
        <property type="entry name" value="Mito_Persulfide_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084:SF1">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="272"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="359" mass="40455" checksum="99E712B74A26F86E" modified="2024-05-29" version="1">MSRFVKIRSFSSARSLYSNLTSKQLNFKQCKTYVLQDNLQKEALLLDPIKENIPFYLSYLGYHGLKLKYIVDSHSHADHFSASFKLKDLTGAKYVMHRSAPAPRVDHHVVDGDILEIGDNKIQVIHTPGHTPDSISLYTGSELFPGDTLLIGGCGRTDFSGGDPTQSYESITKKLFTLPDSTRVYPSHDYRFNEVTTIGHEKKTNPRLANKSKNEFVEIMENLGLPLPEKIMEAIQINSSTVLEDQIKLPTYSQLNEVKLISPETLKELKKDKESVLVLDVREPEEFEDEKLKGLKDTVNIPLRSLVTNVHQFEDYKNKTIVCLCRSGMRSATAASVLSGYGFENVLNLKGGLLNYYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9E9</accession>
    <name>A0AAD5U9E9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9E9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37314">
        <property type="entry name" value="SLR0142 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37314:SF4">
        <property type="entry name" value="UPF0700 TRANSMEMBRANE PROTEIN YOAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="362" mass="39688" checksum="B7051C2C84099552" modified="2024-05-29" version="1">MNNFAAKEFWSIVVGGSVLSLNAGFINVVTLAGVFTITVSHVTGNVTRIAITVFQGDWATLALVVSIMFSFMFGAFVSGVFVGDNKFRLGRTYGYALLLESTALFLSYYFLKKELILGEWCAAFACGLQNALATSYSGAVVRTTHMTGIVTDIGNILGQACRTDTNAELWRLKVHVPLLLSYIFGGLLGQAAYLGLHENSLLLPCFFTGAIGMVYLFLPFMNQATEILKESTKQMRLDGFRPIVEVRAIGDPRKVDKFQSVVGKDVDLEIKNFEKEMAIVNVAKMSSEKTLNIAKDNELQKSVEIKGISNDSNKSNNVGEEKSFVLQLKNLKNKDGSRIGGSKFDEGFLNDSSEVLVSKENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA66</accession>
    <name>A0AAD5UA66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA66"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="118" mass="13714" checksum="5E11ACA4091E0667" modified="2024-05-29" version="1">MIQRGTYSFKSEEENEFNLEGYEFIVKLSSVDNTIARLYLVNQNKVQVDVPANISLRNFDENTAPNHFQNSFFIAWVNSYALLIWSKNSEHRTYINGVLIPPKKRRAAVVVEVEDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAJ9</accession>
    <name>A0AAD5UAJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAJ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="304" mass="36114" checksum="BC5041C92110855F" modified="2024-05-29" version="1">MKKISIPQSNANMVKKFLKSSRFNFLKESELTSPIPKILFDGKSTFLTFPWLLSTSKKRFKPTFWNTFKQKLVFAFTMNRIQKKHLKKPHFDFPTHFYDDVEEIIEKLFQHDLSNISNCTSMVKCLQNIFNKEYIDLRKRELTVDFKFENLQKKPEFDIQITEISFIYGPHPIPPNYVVQNWPIHKLIIPQSDKVGKNHQHQEQIFRNAMNEGCCIKIYTRVTFKQNLQFIVKDGAGKILIEDYRNNFDIQFCTPNFKPTDNIYEMTSPKKKHLKFDWKISDIDYLIYGTILESSASDTFNNYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAR9</accession>
    <name>A0AAD5UAR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tuftelin-interacting protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TFIP11</name>
        <name evidence="4" type="ORF">HK099_001671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFP11/STIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071008">
        <property type="term" value="C:U2-type post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022783">
        <property type="entry name" value="GCFC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045211">
        <property type="entry name" value="TFP11/STIP/Ntr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329:SF1">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07842">
        <property type="entry name" value="GCFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="3">
        <location>
            <begin position="206"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1221" mass="141989" checksum="45CBDDFDC30C3C1F" modified="2024-05-29" version="1">MGKKKNQFLYDDADSSDQGDSDQEELYGKKRKHNKQDALYGVFGEDDYEDNNNISFMDDYKKPQKVDFVKKAETDSSNEEDEVASDGDAMSIDVKSDNDEEEPDLRHEITEEELEEEEHFGIGLGGLGSRTGLGLDPAITSSFNNQSTLNVNLTKKTLEKNITKTVQIEATKKVFANPLKTSNQLLTTKITPRPVDKNFASFTKATTGFGLKMMQKMGYKKGEGLGSDGSGIVNPIDVKVRQGKIGVGGMDERTNAIKEEQRIKKEALGLKEEEVKPVLVKHDGWKKSKKKIKKKYVSAADLIKEQEILEGEALPQKIVDMTGKQAREVSHLSELSTSKQVVLNIQTRLPELKHNLLLIVDIASNDLIDHTKAMISEKRNVEDKSTQIKKLDYKLREQNYKKGRVDEVIVMCKEFQQRALNLDIPHSLKENLDDINNNNSELRLEWIIKNFEDLFLKFENHYFQEYLQLKLDEVVFTVLAKFFQNFFHKWNVLSQPTSGQKTFFKLKKLFCYDRYISDKKEAKNEPKLNFYGEEIEEDILPQPELLMTCYENMLYKHWLPKVRSAINNEWNIREPEAIVELLKLWHPKKEFDEDIDADVTSYASKECVLPYWLYLNVLDQLILPKLKMELNNWNPKFDVDLVHTWIHPWLLIFDEETLEKEIFENLRFKLGLYLKDWHPRDKLASEILEPWKDVFSEKVMEGFIFKHILPKLVQCLQTELNLNPTESNLKPLEYFLRFKNLLTNDTIENVFEKEFFPVWHKVLFIWFNQPNFNKKEIGDWYKNWKEIFKENNIENLTQMKIGLKIGLDMISLGTKGMLNSIPKSYNKNEEKKVKVDKLKKTFGRDFGLTFKDLVEKTLNENGLILSPLRKPHPVNGKALFQVSEDGLVSEDNLSITIYFDEGVLFYEDISDKGTRWFPTGVQKCLWCSREKLCNLTLRHKGDIKSHAVVHFNDIRPIKCPFCSERMKNRQSLHRHKSVCKNTGGIRSDDMVETCKNDVVCSVMENKTDMDAVRTTPPRYNSVQEHDIKLIQELYSILASSDQNFNDNFKENDTENSWIQELDSLTSSTTFKNDENSHLEKNIYIPSTASLQKGILNSTFFINKRKNVPNRSLRNLDYTNFLQFCNNPALETNNLIIPKTANNRIMPNPALIALKEEINFLEELDIRHSNCNNYDQTQGCSFNKPEYRNKDYMINEFNTSIVSNTEYSDVLPFIDQFMLMEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAX7</accession>
    <name>A0AAD5UAX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MEP2_1</name>
        <name evidence="14" type="ORF">HK099_003861</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAX7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041777839" description="Extracellular metalloproteinase" evidence="12">
        <location>
            <begin position="24"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="294"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3226909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="701" mass="75645" checksum="5F7F78E8E1ED7F1B" modified="2024-05-29" version="1">MKSSSILSIASIVLSVATSPLTGNPTATKEMLPGYFNPEASFEVYDVGNNAARTPKSAEQKQQLAHDHLVGVVSGRFAKGQAPDVVLTSTVESIGDVTTFHYAPAVDGIQVVNAAANVNIDNSGNVIGTGASWLKTGLTVKKGDKFSAIDALKSLLTKLGLTFDPTKFVETKTAEGTKISGLNDFGDVIISVKYYRTEDTLEKVFDIALPLKDHYYNGFVEMNEGKVIGLNDWMVHEHDVEFRHDAGRAPGKSFLKKRVDYKYNVVGFPHEDLSEGRVILTNPADKVASPLGWHNNGSGDQPTTIGNNVQAQDTQQNTPRRVTKPDYNFDYPIDETKDAKTYWEAGLVNTFYVTNAVHDITYQYGFDEKSGNFQTNNFDKGGKGNDHIIGNSQDGGGTNNANFATPPDGQSGRMNMYLFTQSTPNRDGDLDNCVVTHEIMHGISNRLTGGPSNVNCLGTTQAGGMGEGWSDVNSYVLTAKATDTRDTDRAVGAYVMNKPTGVRQYAYSTDKSRNPLLYSSIKSSSAVHFIGTVWGTILFEVYWNMVDKSGFSTDILHDAASGKGNTDFFQFLLNGMKLQPCSPTFITARDAFILADKNAGGKYHCDIWKGFAKRGLGANAANMVDNYDLPEACGGPQPSPSPTTTTSPGACAHDKCTTGSALVATCDTCVGKICDADPYCCSNSWDSICVKAVKSVCNITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB18</accession>
    <name>A0AAD5UB18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">VASt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_008284</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB18"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140268">
        <property type="term" value="C:endoplasmic reticulum-plasma membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120015">
        <property type="term" value="F:sterol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13220">
        <property type="entry name" value="PH-GRAM_GRAMDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="611"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="8">
        <location>
            <begin position="330"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="664" mass="75312" checksum="C9DDCEF85D0057C1" modified="2024-05-29" version="1">MPANETESADRLKPFYSNQGHSVSTPNLLLSSSEVDTKTLEPVDNSTYPSSDVDSNSKLREDLEFHKLFPNIKLSDHLVTHYSCALAKDMLIQGRLWISDHHVCFRGWKDEPLQIPFYNITHIEKKSVAFVIPNAIEIETEHNKYFFASLLKRDDTFYILEKLWDKHVPKTSHFRKHPLNEGVVQCTCGGLGTCHACFKAYSSNNEFDSTNKNQTDVDNMIKVTDENGNPAAGSIILSVEKEQLLKDSSNVEITPILPISNFTEGGKLDQHGSNGLLVKSKEGDLVSVLSPTEDESMQSSLLSKKKKHHRKRRNRVSMNSKSCNCDINEKERVLLLDKIYNTDLNTLFQLLYSNGENVNQVYTESFNGRIIVSRKNNNIQCSEWTPPEEKDSLVLKNAEETCYKIASLDQIKKGSIRKMEYITPISNPMANKTRCIIEETIHDLKEDHFVCIFTDTKTPDVPHGNYFSVSIKTHLTHAGPNKTRLCAAYKINWTKSSWLKSAIEKGVSGGVKTSYAELDEKIEEHLINLPLSMDEEDECSDDQAKAKEPATVKVKPSINRKSATQPLLERQPPVVKQPAVVAQLNPVLAEEKSNVLHTFFKELNNFGTSTFALILFVNLLLLMVFNIIIIWRVSLVLERYDERLDILQKLVFTKVLGKDFEGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC43</accession>
    <name>A0AAD5UC43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC43"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="855" mass="95586" checksum="4BC97BD9BDC4E07D" modified="2024-05-29" version="1">MENKAEEKSLNEALTSLSSKFLIQSGRMEVDDAAMTSSFLKKKPENSEEVESLAVVQNEEVDEVLAELLSMGFTFEHSEIALSFCKENRENGKSLLESCLNWCLAVQTDNGSDNYPQIKDKTVATLKTGNLESPPPKIIVKSSIMEEATTEGVTIDYSTQDTIATILQNSFFTLNNAATNLFSTVSGVAAINNNSTKENEISQPAESVAVSNYTETFSHKLFKNPFTLSENKSMDSLTDSLNNFQAKIIKFHSFDEDFKNSSKMIAQQGKIIEDKNFTNYFESTNVVNENEDSFFNGSDNLLNTTTSDKLSTIRGSTQKLTTCIHAKSAKSVGNTQYPDFLLEQYNFYVEKCQELNEIPIEKLFLQVKSLIDTDLSLNLTSLDLKNIPINSNNVASLSHLLLCLKFLSSANLENTSLEDFGLKSILSSILTSCCPFTWLSLANNGKIKFSGIKFIAMFIKKVKWELSKQLKFLDLTGLPIDRKGMSYISYSLGAILKNDMNKKSNKPASLEILKLDNSKLGCSNEKESIVEIFSKGLCKSNLNSLSLSCCSILKNDAKYLFESLRFFKDVEKNLFQESKIVSIDLTGNLIKEGVSIIAEALPNNQALKNLILKNNQINSEGLKILADGLKINTVLEKLDVSCNPLYSNENPEGIHALKDALYYNSTLLNLSLTNIQLTSEGAIALAESLPSVKSLRFMDISSNPINVAGVLAISISLKFNQSITSLEILPFLNPPLPLQSSFFQKFVTKQPQVFPKKNFEEEEEIAKYLNDIVIYCQRNFEIRRQKTREMSNLVLDENCYFQEQNKIESSVATPDVEQIILEGESTLQLFNDIVKEFNDTGKCTQDELLHVRKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS26</accession>
    <name>A0AAD5XS26_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001738">
        <property type="protein sequence ID" value="KAJ3201367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS26"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="30737" checksum="09A0657519C930C2" modified="2024-05-29" version="1" fragment="single">EDEGNLASHIKRMRKNGVFGGNMEVCAFAREYNVDIVLHQVNSPVWVVRGDESNDNLKKIHLIYHSWEHYSSVRNKDGTLNVLQPKPDELEGEEKIVNQSLEISECYNEDPILNFELESNEIELHEDCLLGIAKKDSLREEELLLSTRNINIDTDDSELEKKKMPLEEEEVLLEANGNLPEQNLKAKIVKEECKFEILPSNQNVEKITNNVNEIKVKKKTKREKKIEQKVRSKQNRLNKLNKDFHVNSEATLNNQNVFEKSVVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTP8</accession>
    <name>A0AAD5XTP8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copper type II ascorbate-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000706">
        <property type="protein sequence ID" value="KAJ3213478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTP8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.310">
        <property type="entry name" value="Copper type II, ascorbate-dependent monooxygenase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014784">
        <property type="entry name" value="Cu2_ascorb_mOase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000323">
        <property type="entry name" value="Cu2_ascorb_mOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036939">
        <property type="entry name" value="Cu2_ascorb_mOase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024548">
        <property type="entry name" value="Cu2_monoox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008977">
        <property type="entry name" value="PHM/PNGase_F_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF23">
        <property type="entry name" value="MOXD1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03712">
        <property type="entry name" value="Cu2_monoox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01082">
        <property type="entry name" value="Cu2_monooxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49742">
        <property type="entry name" value="PHM/PNGase F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042041262" description="DOMON domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="5">
        <location>
            <begin position="45"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3213478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="525" mass="58214" checksum="921863853BC320A1" modified="2024-05-29" version="1" fragment="single">MFTKLFLTLCILILPTVFAVSAPQWVPFKTDAYSGHQTLTTSSNKSIELFWSVDVAANQVEFGVASKNGATWLALGLSESGSMQGADIWLGYTDPTIGKFVLEDRFSPSVGAPILDKKQDVTLLQSFQTAELTAFTFKRSLTPCDLSQDSKIETEVPNHFIFAFGTDNNFNKHLPGRNGIKEIELIGNYFTNINISEADQKNSTIFNMVTKKIEIPANDTTYCYTLYDLSDMDKSHIIKEVPVVNSPLLHHLVGYLCDTIPANITTTEPICNVIDPITQLSDSDFQNTCWRTYLLWGKGGEGRTYPATAGKPLGRSAYGTQYLLLESHYANPELLTGQVDVGSGLELTLTKNLRPHDVGILFAGRDQDVILLEPGNSSQSIYGRCGLQCTEKGIPDEGLTITATFFHMHKRGISGETQWIRNGIELPPLTTRRYYDFNFQISQNAPLSQEKLMPGDTLITRCTYDTSKDTKPVRGGFTSDNEMCINFIEYYPVAPLFHCTDTIDIPAQLNSTVKDGLFCGITKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUH5</accession>
    <name>A0AAD5XUH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000507">
        <property type="protein sequence ID" value="KAJ3215956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUH5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="98" mass="10852" checksum="26F03D3528A9A718" modified="2024-05-29" version="1" fragment="single">MTQQQLGTDTFTYDSNISHESDTKTSIFNNTIVSPVGNSEADFQQPASFTNVINNDTNGWDTLSLPSSEYDHFAEPGMKGNHKSNAHATHKQMDDIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUL9</accession>
    <name>A0AAD5XUL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Golgi pH regulator B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPR89B</name>
        <name evidence="3" type="ORF">HK099_005888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000480">
        <property type="protein sequence ID" value="KAJ3216401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUL9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="2">
        <location>
            <begin position="116"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="298" mass="34249" checksum="E67805E881DF4E57" modified="2024-05-29" version="1">MFMFLKNVTNADVHSAEKKLLQNMDILLSKKKKLCLKLYQRKEKQKLAYNSSLGEKSNLNVFGYFKKVYDEVQDNFSSGNESIKFLENEILALQNVNKQLFLDLDDLNMELDRIEFSKTLKGKYYNLLGYVFSFYCVWKIFTSTINILFNRSGGVDPVTHGLNIASHYLGISIDLEFWVQHLSFLFVGIMVVGSIRGLLIQFMKVFARFSNFISPNNIVLFLAHIMGIYFLSTVLMMRMSVPPQFSDNLTATTDNGLTVLKNITKENFKSYQGGAKQLSQREHNVQQYVAKFGTPSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVS3</accession>
    <name>A0AAD5XVS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004228</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000293">
        <property type="protein sequence ID" value="KAJ3220538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVS3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042154062" description="SH3 domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="320"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="43802" checksum="5F4DC9CA0EC71C90" modified="2024-05-29" version="1" fragment="single">MKKLIFYNSLLIINVWSLWSQNLLLNGDAERGSEGWTVECGTVVTPLYTDFRNTFSLLSNAKNEEFGKHLFSGKNDSKIYQNIVLDQFSRYLNLTGWITNSFNGKDFVSLEVYFLDKDSKVGEGAEIKSRKSADKFGFKFQQLLLEIPNNTDSVRLTVHFYSAQNFDFVLGNNNNNFTQSFIDNLSFQTYEGDEVFEEVNNVGIQKSITSVKNTTVNDSKKNEPIVFFKEDVKLNWNHFLAIISSVLFFVTLTTYFSIRFFKGKKIEKGTNFLVLDDVDVIYEETYLPTFPQKVLTRKESRKLYRDREDPMEVGRQMLLSRFTIYRVFNSYYPSSTDELELEIGNLIHVEKIYKDGWALGFNTTTQKRGMLPVSCVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW04</accession>
    <name>A0AAD5XW04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TRS31</name>
        <name evidence="8" type="ORF">HK099_003909</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000263">
        <property type="protein sequence ID" value="KAJ3220924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW04"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000002">
        <property type="entry name" value="Trafficking protein particle complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="199" mass="23103" checksum="66337C05F01AECF6" modified="2024-05-29" version="1">MNRPKQQQSIFDRPLNKTRNYEVFPHVIKIMIKLKNYQTHSEMLQYSQKSVNGIQELEKKLSDFGYKVGLRELELTAWREKNTRRETKVLGILSFVHSTIWKSLFGKVADALEKSSENEDEYMLSDNDPLVSKYISIPRELALFNSGAFIGGIVEAILDGSNFPCRVTAHSTANDQFPLRTTFLIKFDKTVMQREKEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW29</accession>
    <name>A0AAD5XW29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="2">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">GUA1</name>
        <name evidence="16" type="ORF">HK099_008001</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000833">
        <property type="protein sequence ID" value="KAJ3211449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW29"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000002">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000848">
        <property type="entry name" value="PRK00074.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="15">
        <location>
            <begin position="203"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="231"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3211449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="536" mass="59696" checksum="4C9661BD115A68FE" modified="2024-05-29" version="1">MDKLEEISQLYDTILILDFGSQLTHLIARRVRELGVYCELLACNINITDLKFKPKGVILSGSPYSVYEKGSPHVDPEVWKLNVPILGICYGLQEIAFTHGGAVECHDKKEFGHADIKIVEESKLFEGISTSMQVWMSHGDQITKLPTDFRVVANTDTAPFAAVENVTEKIYGIQFHPEVTHTALGKVLLKNFVVGICGAKGNWTMESFVDKEIERIRVMVGPTAQVIGAVSGGVDSTIAASIMSKAIGSRFHAVLVDNGVMRLNECNEVKKRLTEKLGINLTVIDAADLFLGRLKGVSDPEKKRKIIGNTFIEVFEKEGERIELEIEEDIKKGTSGNRGKIEFLLQGTLYPDVIESVSFKGPSATIKTHHNVGGLLENMKLKLIEPLRELFKDEVRAIGTLMNIDEELVWRHPFPGPGIAIRVLGEVTPTQVEIARKADYIYIEEIRKAGLYRQISQAYAALLPVKAVGVMGDARTYEQVIALRAVTTTDFMTADWFPMPYEILKKISNRIINEVRGVNRVVYDISSKPPATIEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWI9</accession>
    <name>A0AAD5XWI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001858">
        <property type="protein sequence ID" value="KAJ3200658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWI9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="467" mass="54178" checksum="44149E4267334038" modified="2024-05-29" version="1">MKLRNRQQLNAHKKIPCRLNEFEENENNIESAPIFNNLESKIPPKKKLLMLDTNKNEIDNSNLLDFNEKKEFSKLKMLNSSSSSSSSFESFDNFYTPDQEIFSLKNNKKIKLNDEFFLITPNTSSSPRRKYLTAVDFVTVDKEDIYFERDRLENLCESFAELKLNSISQSLCSASLIGVNVLFYWGLCSSLTESLNIDIPDNIKYSFIKVYKYSGVIGKVSPTVQFEFSMKINSLKIDKNFNKKISNALTDYKIKKVYGNFIYNIVLNISKNLGQISQEILQYYNFSSSFQKTSVIPLYNKMSPLKQFLIAIVKVIKQSIIDDICNEDEMIFLEAIENTQLYRSPLDCTGQSLVLKILPLFNFEKIEMEKKNCILQLVRILQLEVNEVCKKVLSNKNFEKAFKQTCCLGLICGFNNEVKFQMDYIVDIQSGQFGKFYFVFRLGCDVDFVFDKIIDINEFVLRPVDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX50</accession>
    <name>A0AAD5XX50_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Outer dynein arm-docking complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Tetratricopeptide repeat protein 25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TTC25_1</name>
        <name evidence="6" type="ORF">HK099_001114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001298">
        <property type="protein sequence ID" value="KAJ3204455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX50"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040111">
        <property type="entry name" value="ODAD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040:SF2">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="464"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3204455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="531" mass="60189" checksum="8A783D812E107F5E" modified="2024-05-29" version="1">MLKFDVKKESVQTSALKAPTKQKVLTKEQVSFQNSLFLSLASEGEALVRKENYSKAEVCFRKALAIKQKLIANDIGVISTFDRDRVNCLILRSHCRLSSGDAAGGLEDAERALLECSFSQTTATNYACALLARAEALYYSGDFEKALLDFHKGERERPEISQFKAGVQKSEEAISQAILEIDAGRIKEKRKIGLQKEEEKKKLLTSSQTKPSRQQHHPPSIQSFLNSKKKSSARNSTVHPHQTISKTVNSNPSSPNNSNAISASNHLHSAREEKLSIINEVSQHLLINPQESNQQYYQLEQQLQQPKHGHFSSVQKKSESKKKFLVGNQPVINTYKKKEPIDILEKVLLEEIFDDKIFLLELTQDSCFMKCGKEQIGKLVYNAIDYLNTRIEFWRQRNPTASATTGKGRPQSSKSIIKKVIPSRQSSAMSNRRPMTAKSCGLEYTQKLISKAPTKPLLAWGSDLTSSQQSLVKNEQNLKKIREENNKKLEMLKNLQLPKKSNSKVEFNFDEKLSMEKRFEKVQKIYKTVHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXF2</accession>
    <name>A0AAD5XXF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005691</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000456">
        <property type="protein sequence ID" value="KAJ3216874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXF2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="5">
        <location>
            <begin position="10"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="136" mass="15290" checksum="D7E2FD09F0A2FF35" modified="2024-05-29" version="1">MHVAPIAISAQFAHPLAGPTICGSHILTMWAWMCIALLSTVNSHSDFDFPFLHRGSTRFHDFHHEKFNYCYGTLGFLDWLHGTDTAFVERYGASCLTIGLKSDQEKPKGGLVKKKKLRDSSVDLSYDSKEKSVKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXP7</accession>
    <name>A0AAD5XXP7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">MARK3</name>
        <name evidence="19" type="ORF">HK099_005299</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000404">
        <property type="protein sequence ID" value="KAJ3217928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXP7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12121">
        <property type="entry name" value="MARK_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.80:FF:000011">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000156">
        <property type="entry name" value="Serine/threonine-protein kinase SIK3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="29"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="18">
        <location>
            <begin position="677"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="373"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="454"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="513"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="581"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="464"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="546"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="597"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3217928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="727" mass="81223" checksum="79033A4B5394A42D" modified="2024-05-29" version="1">MSSSKPSTSSKKKEDPVNPDTNLQGIGNYVFQKTVGEGNFAKVKLAKHKLTGAEVAVKMIDKTTLDEKKLNKLYREVRIMKLLHHPHIVKLYEVIETKNTLFLVMEYSSGGELYDYLVVHGKMKEKEARAKFRQILSAVSYCHKKRVIHRDLKAENLLLDPNLDIKIADFGFSNYFDPDSKLDTFCGSPPYAAPELFQGRRYTGPEVDIWSLGVILYVLTTGCLPFDGKNLQEMRESVCRGKYRIPFYLSDTCEKLLRKFLIRDPYKRGSLEMLIDDPWINEGYDCSPIQIDQGTTLVHDESIVKLIEQRFKVDRSTIMQSLNDNQYDDIAACYYLMYYDAQTKGKIESEVQQMSPGHTSLLLPSPTTVVAPELNDGNSKKTGTTTLKKVGEDMEEKGEEEKISELPSSKQMKKEQPRRRRVTVGGADAEFNKVENDDQDATNVLKKIQNNINSKPPQKAQELAVNSSTPVQATNEVTKKGNDGKAVSTISEVAVQKPATPVQAVATVEITSPPLTAPSSLSAEKEDPQVRKRNNTIVGILRSTIRRPSTNEGGATSQSPSNDKGALDFPQQSAVVANLPASPPLSISHHQPTPPGTTNSQQKVNQQVSQQGEDDSMEVSDKPGEPRSLRFTFNSNSTSSKPPDDIVLEVIQACKKHSIQQKVASKFLIECQTNTVLVEGQEQLKFEIEICKLPRLKNLHGLRFKRLSGQSNEYKIVCEKILATVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXU4</accession>
    <name>A0AAD5XXU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000973">
        <property type="protein sequence ID" value="KAJ3208843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXU4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="606"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3208843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="710" mass="79591" checksum="0CC22035C971F483" modified="2024-05-29" version="1">MKDWERNLESVEEIKFVGGVKIINEHSVSDSNYFIITNSTFVGCLDVASGQEIWNYKQEEILKVLKKINSVIVVKGKKNQKVESIKVLDGKILWSYTIPFDLEKYYTEEKVPKKNIKKITDVAFFEVRDYEDRLIRLDVILISGGVVLSRINGETGESLFETKNEAGIIFHTIYVTQKIIYFLGTNSNMFLNDKPHAVIHGYDQEKLPKLTYKNSFVLSYNNNNFLLFGETLKSLGTPAEKFTLWKADLGAKGKEILIGSFSKDLLKPLGLFDMKFTGANKENLRISDCLDLNLIDVYNSENIYSNKFMLECLTDQVNNKKHWILTLAVNGLNENPEITAFSLPQLNNTLLEDSSEVFSFSDVTSDSNVGIRIYETTDYDLQIAMKLVHVSDSSISLGETSSNLTKHQLTPQHSPIQRRKKFVPSSPGNFTEGLGSFIYAPQEKLDLTIKSDRARHKAFNNESKIFDPPTPITPNSPKDLKGTGSSIESKVRPVGSGKKFIKREDGSYNNIFGANGDQETQNNSSSKRLNSGIIPNGEEISTVPSRRLHPSAIKATKIIFEEEDSINNKNEVEKKKQSTKKIFKHSKNSSNIFFSSNDEKKSENATINNSSTYNKNKSSIRFGDDHSSCEINDEGSQPGENSINSASNFFNEKSNVKKSTKRFIPPPGGNGFSSMADYCGLHVEDKVEKKIDPADIEVAAGSITGVYGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY21</accession>
    <name>A0AAD5XY21_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tubulin-specific chaperone D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004731</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000342">
        <property type="protein sequence ID" value="KAJ3219334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY21"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058033">
        <property type="entry name" value="ARM_TBCD_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033162">
        <property type="entry name" value="TBCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022577">
        <property type="entry name" value="TBCD_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658">
        <property type="entry name" value="BETA-TUBULIN COFACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23579">
        <property type="entry name" value="ARM_TBCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25767">
        <property type="entry name" value="ARM_TBCD_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12612">
        <property type="entry name" value="TFCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin-folding cofactor D ARM repeats" evidence="4">
        <location>
            <begin position="282"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="355"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin-folding cofactor D C-terminal" evidence="3">
        <location>
            <begin position="918"/>
            <end position="1114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3219334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1207" mass="138986" checksum="4A2C1F85D8CA6FCF" modified="2024-05-29" version="1">MDQFLIQIRCNTLKLLQCDKSNEGDSCAYISSQLSLQKDLDYFQEQPTLLDRYLEELITFTMGNIKEIINEKFLQSDDDLFKLSADITFNNKFKLIYYFCKVRGYKTILKFFPNEVGIFEPMFRYLSLLSTKDFQLWEQRYVLLLWLSLLSIVPFDLKDIDSSSRADTLVNDIVNLCKSFLEKAGKEQEAAALVLARILTRKDTVHIKLKEYIEWVLDQLSNNITLNVFKICGVLNSLCTIFKFGPREILNEEINRIVQTKILNSFFTENLDFNEDFQLNSLVRKCIVKIAQRLGLSYLKPCKVLSWRYTRGNRHLEENLGFHDSQKLNKFSGRNNQLVDAEQEEADVPEEMESLIGILLQGLKDKDTIVRWSSAKGVGRLTERLPKAYSQEIIASVLQLFEEDFYNDDLSFVSDCTWHGACLCIAELSRRGLLLPENLVSVVPQIAKALLFDVKRGSHSIGSHVRDAACYACWSFARAYSAEDMLPFSRAIGDVLICNSVLDREVNIRRANSAAFQESVGRLGVFPHGIAVVTTADYFNIGNRSNSYLKVATEISNFEEYKLPLIKHLVSRSVPHWDMEIRELASKALGKVTHNAKEFVVSEVLPELVSRVNSADLNVRHGSLLSAGEVIVALSEMYDKSLDCWICSTNTQKQLIENITLVVVNYPQKFLESFGWELTRVALLNFISCLCLANWPTTQDDKFKKFSHNKLERFVNISGNNDGHSPLLDLSEQIWNFLQLCLECKEEKVQVKSCLALKDFSEWVYTENNKNLCPFFEYYITYALDQLKSDRMNTKHIKRGVALSFKFLHFKGLQYRFDEIVDQLILNTMEKREYLYDAEIKRNIIIALETLLINSEDIVNINQYDKILQCMIGCLDDYSTDLRGDVGSWVREEGIKGLKYCMVVGNSKHFLLKSKAVEVMALIFRQGCEKIDRVRETAGKALFDLIWIDYWNFDFEYLRTYFRKDLDINWLNPSEVFPFMTQFLNYSIFQIEILTGIIVSVGGLTESLVRFSSASLVNFLLNVPTCNSTTQKVEITMSLQNFFSILNEIFSRNLKIDRISIPLLETLDVLSNAEVFQNLFQVDMMEQLTYSVNIIERLIELVLKVLFKSKDTKKLIIGIKVLSSFIGLTNLKLLDLDEEEVGDDDLKTNLSRCHYKVVKKVVSYLCHPYPKIRRVAAEQLYIVVSVGAILSSNNIEEVETLLLEENW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY45</accession>
    <name>A0AAD5XY45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000843">
        <property type="protein sequence ID" value="KAJ3211309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY45"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF1">
        <property type="entry name" value="REDUCED VIABILITY UPON STARVATION PROTEIN 167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="4">
        <location>
            <begin position="15"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="3">
        <location>
            <begin position="349"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3211309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="424" mass="49202" checksum="E7D7A0731C0B7EE9" modified="2024-05-29" version="1">MSWKGFTKGLARFPQSIGAGSNSVTIDQEFNHYNEEFNILDKLSVKLYDDSKKLHDSLTAMLKHQASFHATLVDIFSPLNLSKLGSNDSIENFQDESPVSRELEIALNQTKESSQRMDEIKDRLLPELENLERRVVLPTNDLISLLSNVKLKIKKRGNKLLDYDRYRDQVQKLKDRTDRTVSDEKKLGQLETQLDQSTREYFEINSLLLKELPVLLKLRIDFVDPCFRILYWYQLKVYSTLSSAFTEIIKRQFSSSAGAKPIEIYRKNEAAMLEALANLSLNKRPISYNKEPVSLEELKRRKSYEDSRAFQSPTKERLPSFAELHKNTNTFKGSSGVTLNNRSSFEGAKKIEFVVALYDYTSDTKGDLQFSRDDRIEVLERNESGWWKGNLFLKSIVDFLFFRKVQGRSGNVSRKLCYRYIILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYA9</accession>
    <name>A0AAD5XYA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005813</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000047">
        <property type="protein sequence ID" value="KAJ3225988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="258"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="336" mass="38531" checksum="12214823F9F1D03B" modified="2024-05-29" version="1">MSISNFNRIGAIIEKKATVAHCTLEKVDYHSNSPIKNGFKVSAEENCAEEDSVQSDQKLSKDIPSCPVNIINGTNPKFVLLKNLETYLNFNDIQHQEEKGELKKSLLELKNFFTKNLEDLYNDFKDGLNVAKSEAINDMKKKLSNLETELETAKEKTNEQLNKIKVNATSTLSDIEKECVELIKKCKIEHVNINKKLQNECIKVFNFKDDLINSEKQFSAESEALRTRLYSLETFASQTKSKLIDHSNKVNNLENFSFEKENLDLAKLEEKVEDLTKQLNLKRKRIEEDVDLLNTLERRILKKNRVDILQASNFLREGVKFTFLTAISIASAVFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYC9</accession>
    <name>A0AAD5XYC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">A4LEA</name>
        <name evidence="14" type="ORF">HK099_005493</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endomembrane system</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Golgi apparatus</location>
            <location evidence="12">Golgi stack membrane</location>
            <topology evidence="12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYC9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11660:FF:000002">
        <property type="entry name" value="Alpha-(1,3)-fucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929">
        <property type="entry name" value="ALPHA- 1,3 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929:SF194">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="172"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3226140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="350" mass="40916" checksum="851B4819ADC7473C" modified="2024-05-29" version="1">MIVVEVKKKDTWLRRSENLKQYYCYLNEESGIETVSENELRSKNNNKFLSFENFENSGGLLGNDYSRLCSIKLTEKTTLGATAVMWVDDHPSLEIDPDIINDKDPGHLRIYFSMESRTNRKVHNPSGDFLIQNYFYDILMTYEMNSTIPLNYLNLNMESELYLNNEIENYKKSKKFKVAYFASNCGDHTGRDKFVAELSNYIEVHSFGKCRHNADPSILFPSCKSCNFAKECILKNFYFTLALENSYDIDYVTEKFYEPLKVGSIPIYRGAPNVAKFSPHEDSYINTNDFQNVKSLADYLHNIIEDDELHFQKTIGWRSERLKNAQFRNLTKFGFDSSICRLCFHIKENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYS5</accession>
    <name>A0AAD5XYS5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000235">
        <property type="protein sequence ID" value="KAJ3221350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYS5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="261" mass="29970" checksum="02C688ACBD28E378" modified="2024-05-29" version="1">MDLTKVVTEEKSLLSTNQSEVEKKNGSIISDEPTLNENNYNVAEPREQSQNGRGFMGGMMRTGFGNGVRPPQDETDFMVPNEPKIFGLVNTKQFLIFYNLFNVLLYILSIILFFVEPNQILDVDGNYFSFTPITLFTHINSTKNNRSDFNFTDLSLNFKIYLVLTVITILIHISLSVSLVVCETGYSIRKLIYILPIPWVVICLFYNTWSSGGLFAFGSSIFPFVVLVMLSWHFWNYARFLDEKKEKELLLEMSEVQISTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYU8</accession>
    <name>A0AAD5XYU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">T-complex protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004596</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYU8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010737">
        <property type="term" value="P:protein kinase A signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="440"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="91"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="440"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="944" mass="106956" checksum="DD0C97ECB87283B6" modified="2024-05-29" version="1">MEQTESGFYVINVLPLKKSAGKPKHLEARLASREKSVSHYYKSVARRKEFLENRKAKLHDRGIHVQKIVENHKFKSSGENNAKLTKIADSINAAEKKRTSILQDLANVNARKVAHAKSVALEHQKKYLSYIEEKKAKIEAKEQLVSNRRQRLLLVPRSRLLDLQDWSLEELQNLKSTLEESAQTIQNWWTIVKLSPLIKSMNLAGVTFQEAKNLPFDNLIKKMQDKSLIEASHNLIDYVKKTSPTPVKWRNASRVFLSAYMIASHPQDAMPVMGDDEKVGLFILFFLLTKFLQVVQIAAISAIEDYEKLSLHITRDAVFQFFNSLSKYYLAFEDWKKTDTKKIVDGMIAHWLELEKLWLSVRHTQIDAEVNWKPKITFQQKSIQSKLAQFGVSAIHKLKKEQKKMREGMQIEVEVQPDTTDDDTSAYESEGNAATELFSTSPQQFPTSGFKNSFDSVKMSRKGSSASSSPVPPLNFDKQEILPKELPTPTTSSTDLFASETTSEFGAYLSNEQLAHEIVRNPDYELKPVKKSKLEEQVTAMAKKAFFDAVRQDFSAGIYLNYVPSLLEDIKKQLLSMLSEKGKLATEIKEHLDIDLIKQQITRNVFDSQQCIFYIVSKLLQLCAPVRDQTIRNITNLNDVAAMFEACLNVLEEMKLDLINYKLKSLAPVLKNQAVEYEKSKFKAAVDFGAVKLVNTEIWLRNAFESLNAVAIARNPEKISNPENQIRFEDVYNEALMNVIFSNAAVNSETLPETLRLDANYLFQLQNTAQLITIVAALVMLAKNASPELRRKNQLLLNLRNRLFSMLKSADDGTESTITIDNLVLEIIKSCNEALCQSRTANDNGKDMCLSAENENLIKAVVTRTLSSKDKLYSLLSRRVQNCVRGQLSTGSFKSVTGASLASVGLDIVEKELVEFSKKVYLLGSHNKLVHSEWYDGLLKSIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYV2</accession>
    <name>A0AAD5XYV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000439">
        <property type="protein sequence ID" value="KAJ3217183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYV2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23528">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23528:SF1">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="44974" checksum="EC72F2488CD68E3F" modified="2024-05-29" version="1">MNNHKEANTSSLNDSNSLSSSPPNYSAVDVNSRSPNTGEATENEPLLSANGTPFSSFLFANIVIPGHVLQIVGKSKVGSGLATVNVSSGIVHLLSVMLIGELNDCFTSKYGKRSPFVVFAAIFFIFSYFIFMWPVYPLSVYALGNCFLILAATMGTIPFNAFMTEITPESQRSLVSSVLGINTIVGCLCAAGLGIFFEQLQTTGIYIVMAVVVLATAFVTSQQEELEINYSSHIKFEHLDFLQYWILDCTSSDIGGEQGVSLALIPLLLLSPFGAYLIPKSRRKIVVYFSATLMCISTLFMMLARTYWVTFFISAIFGIGYGPFISVEFAMLMDVMNDMPATSAAKNIAIWHSASVLPQLTGQPLSGIVRDFFQAYGNDLNIDCLGYEVVFGMTITYLLLGVLCTYLMRGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYV9</accession>
    <name>A0AAD5XYV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYV9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="223" mass="25237" checksum="9603702FB4FAC171" modified="2024-05-29" version="1">MKTELALSGAMESSSSIISTADELAKNDVEEGSHPKQSAVLEEQKCENSNIEDVTSKKSNDSSKTNFTAKFSLERNIICAYFLLVFSFSIFLLANVHNLNNELAKIVYVIVWAIRLPVALLAIFIVKILSKPKVTEIFFYAVTIFFVAVFAIDVYFNVVAANRLNGYIPLETSLTILEFFCSVLFYSIVRNDTGFFWSRKEPSNEKDDSFYEDDENELRNEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZK0</accession>
    <name>A0AAD5XZK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein fantom</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RPGRIP1L</name>
        <name evidence="9" type="ORF">HK099_005507</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RPGRIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000430">
        <property type="protein sequence ID" value="KAJ3217378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021656">
        <property type="entry name" value="C2-C2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031139">
        <property type="entry name" value="RPGRIP1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14240:SF1">
        <property type="entry name" value="PROTEIN FANTOM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14240">
        <property type="entry name" value="RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11618">
        <property type="entry name" value="C2-C2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="636"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="923"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="982"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1136"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="49"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="143"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="455"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="923"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="950"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="988"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1014"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1049"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1068"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1095"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1141"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1152"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1177"/>
            <end position="1187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3217378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1325" mass="152177" checksum="FE60DB62CD371571" modified="2024-05-29" version="1">MNSSRNRGGLLGIGNHHVGKISADEDALYTLKDDNLNLKKKLNSQDDKTKKLLTKVQRLSEDLRKAQSTSVKDSTKGVSSKKEEIENEYAITDLKSKMHEISKQNNQLRNKVQYFKSLHEAEVRKRAPYDHIPPRIHTVYLNYVEVEETDTALNEDIQKLEDLVYVLRGKLIEVEQELEETKTALGSVQEENTNVQKRQDIDRLGLQRDLVEKNKKIQNLTRDNDMLEEKYKAISETHQDALMTVENLTLELKEERQRVLDLDSQLRDFENEREKNFELMEMLKDIKAEKDLLENEYNNLLNNQFSKEREKEFRIELEKLKSENISLEREIQQYINEKATMLNKLKDMTENLKQCQNDKEFCEKRMLELQSQLEALQDKVRHLTLDGEIDLNELDEALAVVRLRRQKGVPLEFLIQVDELIDDKKLLQELRLQHAECIQELEKTHKLLMLQERINKDYKGEVEVLNKKLEAMRNEYELKLEENSRLLDLRSNKIAHLEAQLREILYSTVKVPSEAVDANKDEEEIELEHGQNLMEIHIEGALISSEGLSMIKKLGFEVIESGSNSKNFTTFIHFDFFEFETQITPLGIGSKPHFNHTSRYKKTIIGKVDFSLRMRIPMAQAICAFKERVVALNLLSVGDNNQKTDISKKFGNRAKVNELIVHVKQCQGLIPPLSNLPAVYCSYELYQYENIISDTVKGTTSPNFNFMKILQVPMTTDLDRYLRTSHVYILILDDNDVDNKDYMYGVAKVPLVSLVFNQKVDSIFELQDEYGFKRGSISVSIEWSEPYKLDVNPITRQIEDIQEKTKDGSTLKKFNTILDKKDANKYSSSEIMRQVVMKHNNGINLRDTEGGHKNNPQELAATLDSKNFHDTLFNKSTAKNRYVVSDKILEDNIAEKSNKRMGSTGEVDNEFEENLNLKSSNISVDSMNSHKNSGPGGKYVNTGSDEKYKQSGSSLNSSQLSLKEKKNKSISKKLLTSLHNAENDYHSRSSSCSSSQTPSSQTPSSRQSKKIYNPQINVKNLRSFSNIDMKNSEDGNISQNDESHPSYDVVSRSNSVESSSHSLKYGHTKSSLSSTTSEVLQTETLYAKRKKKNSKSSTNSEKSLKQSLSDDSLKNKHGQYDARNFHDAHEFLQVKSSTSENEVREPHEHPFSNSDSASHSSFENEKKSNSDLLEANDGNSNFDSYQNLPLETNLQSSNFGCDSEQNERSDISSQEIDRFQYLKDKTSEYSDDLNAHNSQWSRSNSNEKIFLENDNKSQITNTSENSECQSQSKDFLKIIVDNLNFDQILQEIQNSFGCTESLIHDADPPIQLLVLSTSFPKKEHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0A8</accession>
    <name>A0AAD5Y0A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YCK1_3</name>
        <name evidence="8" type="ORF">HK099_004398</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000308">
        <property type="protein sequence ID" value="KAJ3220314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0A8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="29"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="357"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="496" mass="56578" checksum="5BA39749C034D83A" modified="2024-05-29" version="1" fragment="single">MSRNSPQQHQSSRQSKSSLNFPNVVGIHYRVLKKIGEGSFGVIYEGSNLVTQSPCAIKFESRKCDAPQLSNEYRTYKLLSGIPGVPAVHYFGQDGLHNILCIDLLGQNVETMFDLCGRKFSVKTVAMVAKRMLSLVQSVHEKNLIYRDIKPDNFLIGRTPRNNDLQYNIVLSIQDFIANHSANTPHPTSQIFIVDFGMAKTYRDPHTKIHIPYKEKKSLSGTARYMSINTHLGREQSRRDDLESLGHVFLYFLRGSLPWQGLKAATNKQKYEKIGEKKQSTTIKELCDGFPEEFGHYLSYARNLKFDEEPDYEYLKRLFDRVLHKIGDTDDGVFDWMIEMQRQLKERAKRRLDRELQYTSRTPTSENSAMKSERAVHQLDTNQLKATASNQTLDTSVNIANFGSSLGLGKDVNKLTLSPTSSSRYLGNLRDKESTGEVDVKIDSICQTAQNSQVTLQNMNNLNNNSLRQHIKSERNTKINQQQNQVNNGKIKKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0C4</accession>
    <name>A0AAD5Y0C4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_008250</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000089">
        <property type="protein sequence ID" value="KAJ3224569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0C4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140567">
        <property type="term" value="F:membrane protein dislocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140570">
        <property type="term" value="P:extraction of mislocalized protein from mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11054">
        <property type="entry name" value="CYP24A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19520">
        <property type="entry name" value="RecA-like_ATAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000538">
        <property type="entry name" value="ATPase family AAA domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF3">
        <property type="entry name" value="FI08533P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="563"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="818" mass="92848" checksum="63C44F58D4C6C5C6" modified="2024-05-29" version="1">MIRLINSLPKAVHLLKNPKFCYSTASSSIAQETLKSFDEIPSLPKDNQNSSTQYFIESGGFDKYPQTMLKLHEKHGPIFRFNFAPGGSTAAPDQISITDTNVTAEIYRNEVEGQVPHRPLLQAFKRYREYKGLPQSLVNTNDDKEWRTQRQVINERLFSPAIAKTYIPRLDFIAKDFVSRISLRNPKDENYAKDINNDIFGFSLEAISSIVFGKRLGTLSADPNEVRDPKIQKFITSVNGLFTTSVPLLFYPPSFPDEQFYKLPEFQEHVKHTDYILELTEDLLKSNNGRESLFEFYLSKEEINPLLARLMATDIFAAGVDTTSRLIQWLFHNLADNPLEIQLRLREEIIKYSGKEGKIDEKMLNKMSYLKDCLKESLRLYPIAASNARILTADQVLLGYKIPAGTQVAMETYSMSRDPKTFTDPELFNPSRWKEEFKQNKSKNKSFSVLPFGFGQRMCPGRRVAENEVQLLIANLIRDFNISYSEGSRKPEPVFNLLMLKKDLQLTEHEEVIATEVIHPDDINVSFKDIGGLEDVIESLQENVIYPLKFPDLYSSVSVLLGAPKGVLLYGPPGCGKTMLAKALAKESGATFINLHVSTLTDKWFGESQKLVHALFTLALKLQPSIIFIDEIDSFLRERNSSDHEASSMMKAEFMSLWDGLSGGDQTKVLVLGATNRPNDIDKAILRRMPRRFPIALPNAVQRKNIFNLLLSTMKLHPSFDMEELVERTKGFSGSDIKEMCRNAVMVPVRESIRKLVDIQNKLDNNNKKDKFNNSSLSEVNIKDVKVRLIVLEDFFAHGDGGVTLGKDKTLTGYVDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0U1</accession>
    <name>A0AAD5Y0U1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit J</fullName>
            <shortName evidence="4">eIF3j</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 30 kDa subunit homolog</fullName>
            <shortName evidence="4">eIF-3 30 kDa subunit homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">EIF3J</name>
        <name evidence="4" type="synonym">HCR1</name>
        <name evidence="7" type="ORF">HK099_002324</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit J family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000176">
        <property type="protein sequence ID" value="KAJ3222421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0U1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.60">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03009">
        <property type="entry name" value="eIF3j"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023194">
        <property type="entry name" value="eIF3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013906">
        <property type="entry name" value="eIF3j"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21681:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08597">
        <property type="entry name" value="eIF3_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="490"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="530" mass="59284" checksum="D1D51AD3BBCA36A5" modified="2024-05-29" version="1">MSLIVATAASCSQKFVRSCINFKIQANKCLQVLATENFPRCTLGCDENISCNFAQKKFCVEKVTLEDNTNVNEILFKYYQYDTSLRKNNEALDCSNLNLHSSSLSCQKPLEPCTFDEHLLNFTKFNTDFPSVSHTHIATFTNDGPQGTSISNDSNISVSFFIYLIVPFIALAILIPCIAMKIRACYKGRKAKPVITYANPTEIAYQERLVPDPVHNEILNNPDFNTTRMSLLSNNNVRPDSPIGLPMTSTRDSYQIDIQSLNPSGSGSIRIIAPILNSSIENNFLQSASASPGNLSIIGWDSESESDKEVKVTLPISAKAKKWEDEDIEEVEDDWDAEENPVKKVEVASPKTTKKKGLKAKLAEKEALGKKDAKVIKHEIEETELERKNRIKREMEASDLENAKDLFGDATLNNNNSTSGLDSMNPKTRTEFDQFLKALSDKFSTFENSVSYPYFVENLVRNITISLSLDDSKKVSSSLTALISEKQKMQAAEKKGKKKKGPTANLKFNEKDTTNYGNEDLYAGEYDDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0Z2</accession>
    <name>A0AAD5Y0Z2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000219">
        <property type="protein sequence ID" value="KAJ3221621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0Z2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="577" mass="63691" checksum="4FCA145ED94644E8" modified="2024-05-29" version="1" fragment="single">VQNFSDGVDNTKLYISTFFNDTLWESSKELNSAIDLCIINAQNLQLSIDSLVKNADNTQNSNLKLESSAKLLQTRSDQFFPKITDINKPQSGPGFGFRLLPAFRLNASNSTLKGIFSAKVENVSQLFDFLRPGQFSDILGYSKSAAINLTLAKSKTSQKVTNFNTNVETTLTSKIPNLSNSVSSGQNSINNSLMVCSNYIDRQEKPFSATTSNEINDILDDYHYVLNSCKSGVSLLEISESFGIFPKGECNLTAIGENVTSTINWDDMLTFVNNDSSDLVPNSVDHQIAPIHDSTYQAKVSAIMNMVELNPSKTVILSQADLDYVNEILIYINNARTKFNATEWYTYLPVGQNTASNIAFVNTTFYNQIDDLEKFINAVFSTGNSSSILNDFNKGRTDVLTQATGLNSDISNLNLQSTVLKDSFDIANSVGNVFVIDSQKKVVKETPNFKISTIQNGASADSSLRNSFSCLPLSRDALSLQNSVCGVFLQGLAANVLAFTAVENDDYDKKNEKEKLENKHKKKKSDTSDFKQESRQPYDDDDQDVAKTTPGGENGNDDDSNGSEQHTVKMPPREVNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y129</accession>
    <name>A0AAD5Y129_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003094</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the THOC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000208">
        <property type="protein sequence ID" value="KAJ3221800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y129"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040132">
        <property type="entry name" value="Tex1/THOC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3 THO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="257"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="59"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="41390" checksum="E737E36DCD68E76D" modified="2024-05-29" version="1">MKLLYIGAGLYSLSVTCAPINNQLNDIPKYRPNVYLQSLNHLNFNNLIDETSDNYQSRWASSLSTDSSSNNFNQQNKPDIEKEELDENPEEIEVDYSLKDNLLSKPEEQTTNTTENDEDYVDLFNSMPMLILNDSDEDLVDINVINDNNSISEDENSSDESKEIFDEWNSEDIENKEGEKIEDPNFYSFKMISDTLYKSSRLSNFSKAKPIDLVNNKNVASTLAWNANGTYLATGSLQTIRLFSCGKTSFTQSPQEITVHTNKVQAVCWHTTNPDRLSSGSKDKTVKLFDLKISFRNHTNDINMGGEVINLKWHPTRSEIVACGLVKEKEDYISFLDLRGGTTSNSEEHNNFTYKKLAADSDEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y148</accession>
    <name>A0AAD5Y148_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc finger Mcm10/DnaG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y148"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="42443" checksum="B4A22D66FDA2F677" modified="2024-05-29" version="1">MKRGCPTNNTLIAKRKVLINEFDLKLKVSKLKERVKETQVFLNKTKSTKTRKLMDETSNKTIPEHSKLSFSERLKLGRNKLKEIESKKEERSKMNTFRVGDIYCFLNLEVILGIEHNYPVALVVDNFGKILKIGETSDIGYCQKEVKNAKCDIVLNNRKSKFCNEHAKKEIELMRRKRQFLVDSVVLIGEPSQRSRSENKPDLNSSYFIPDGRLVSINKNEIKISVPWASKKRYANNQNRHLTKYEEKALKIEEKEDELIANFLSQKNTAGGKQLRASRNIKLIQTAIMINFNVNKMLERVPVFSVEDVKRMGFNPSTNELYREDIPERKKKDEKIEVVKETTNSNSETLEKEKSYIIFSDSENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1M1</accession>
    <name>A0AAD5Y1M1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Triose-phosphate Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CAS42</name>
        <name evidence="7" type="ORF">HK099_001989</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000162">
        <property type="protein sequence ID" value="KAJ3222723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1M1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="72"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="421" mass="47414" checksum="33D3D05AF688AD89" modified="2024-05-29" version="1">MSRRSSIFKMEEDTDFSFLPQDHAGNTTEFFHELDDLSEIQLQTPINSPQNQFTIPKVSFTKTYKKTAVTAFLLMISWFTSSLGLSVYNKWLFSKNHFNFPYPLFTTCSHNIIQFCLSWFVLQIFLPNLKPTAKLSFKEYLKNVFPAGLATGLDIGFSNASFRFITLTFYTMVKSGAPVFVLLFAFLFKLEKINCKLIICIGVICFGVLLMVTDKTNFNINGYLLVQAATILSGLRWALIQILLKNSDLGMTNPFATNLYLTPIMAVTLLISSIMAEGLYTIFSSHFFQSITSILTILGVIFFGGVLAFIMLLVEYQLISTTSVVTFSIAGILKEVLTISTSHIVFQDSFSFTAAVGLIVSIVGIAAYNYIRINDLYQKHQSEVIELEENQAFISTNNFLTNDITPAGEEEEELLIYKTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1X5</accession>
    <name>A0AAD5Y1X5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dethiobiotin synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000132">
        <property type="protein sequence ID" value="KAJ3223384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1X5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00347">
        <property type="entry name" value="bioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684:SF3">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="760" mass="85512" checksum="26E492FFC44838C7" modified="2024-05-29" version="1">MFSETLPIYLIFGANTDVGKTICTTSIVNSASINGYNPAYIKPVQTGYPLDSDAEFVRRYTNASVQTLYSYSTPASPHLTALEENRVISDEDLLIKIEEKILETMKLKTSKLLLLETAGGVNSPTMSGTLQSDVFRKFRFPVILIGDSKLGGISTTISSYESLKIRGYDVPILIFFENKKYLNHEIIKQHVSSETTIFLLTTPPKNENLHNNNGNKDLVKYFEDSAKTAELILKKLAALHKARFERLKELNDDGEKKVWWPFTQHRAFSQGKRAMVIDSAYNDDFTIFKPDEAQYSSDRLFDGCASWWTQGLGHGNPHMAKEAAYAAGRYGHVISPEAIHEPAQALAEEILSSAGKDWASRVFYSDNGSTAIEVALKMAFTKTSLESQKKMLIDKPSNEIIQWNVIGLEGSYHGDTIGAMDISDPSVYNAKVHWYTGKGFWFNPPTYYEKNKRFYLNISDSIVSSVELDTEEIEFNSMAEIFSVKRNKSYLRKVYNKYIVNGLKKFLQNNLNVKKKFGALVIEPLILGAGGMLFIDPLFQKELIFCARNPELWDASSPPLPVVFDEIFVGMYRLGVNLPSVASLFTCDDDFSYLPDIACYAKCLTGGLLPLSVTVTTDEIFKVFDGDSKLEALLHGHSYTAHPIGCQVALYSLKEYKKISLNKKFEWTIWDAQLLTTISCSEKVARVNSFGTILVVELNSQMKGYLSNKESLKLVENLKSSKGIFCRPLGNLVYFMASQRSLRKDLDLILNNIWKAIQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y241</accession>
    <name>A0AAD5Y241_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">serine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SES1</name>
        <name evidence="13" type="ORF">HK099_007735</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y241"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000026">
        <property type="entry name" value="Seryl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="159"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="49"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="290"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="306"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="377"/>
            <end position="380"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for serine binding" evidence="9">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3224870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="480" mass="54498" checksum="667220B5B1C2E32C" modified="2024-05-29" version="1">MLDINLFREDKGFNPEVVRESQRKRGASVEVVDEIIDLDNEWKKARFNANETNKKINGINKQIATLMKQKKKDETKDLVSEKANLQKEKELLENIAAEKEKILNSKLMTVGNLVHKSVPVSMDEKDNVIVMKHWPEGRNEDSEKLRRCKLIKADGKGVDGLMSHHELLEKIGGYDSARGANVAGHRGYFLTGPGVDLNLAIIRYGLDFLEKKDYLKIYTPFFMRKEVMAKTAQLEEFDEALYKVEGGGDNDKYLIATSEQPISAYHAGEWFANPETDLPKKYAGQSTCFRKEAGKHGHDTWGIFRVHQFEKIEQFVLTDTEKSWDMHEEMLNIAKEFNESLGLPYQVVAIVSGALNNAAAKKYDLECWFPFQGEYKELVSCSNCTDYQSRRLDIRVGPKKLNDSTKKFAHALNCTLAATGRTICCILENYQTEKGVKIPEVLVPYMNGKTFLPFVADRKRSGSAKKAEKDVADAVNHIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2X3</accession>
    <name>A0AAD5Y2X3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004882</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000036">
        <property type="protein sequence ID" value="KAJ3226429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051571">
        <property type="entry name" value="N-CoR_corepressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992">
        <property type="entry name" value="NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992:SF39">
        <property type="entry name" value="SMRTER, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SANT" evidence="3">
        <location>
            <begin position="570"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="3">
        <location>
            <begin position="742"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="897"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="3">
        <location>
            <begin position="897"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="897"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1167"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1358"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1167"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1239"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1263"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1358"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1380"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1428"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1443"/>
            <end position="1459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1566" mass="178538" checksum="126F544C97A47BB5" modified="2024-05-29" version="1">MNPNNPTNSLNLGNSIDRVKQHQNSYRQQQQHSISPGQSSGLNQASISSWDSKGQNFNRTGNSSQQRQIINQTNRQTYNNHSQLNVRGRDTVNNRYQRNSSNYPDYNRNQIYPPEHFTGGSNLKRNSPIRQSQQLFTNNNSNKINMSRSSKINQHGLLNNSRFYNRNYQNNRYNNDIKPPGQRSSLIQKDYSLAKPREFMLSKEDKEDENTNISEEKEEDPPEESESEEEGLDIIECLDEMEKIDAEITLNENKLKQRRAQIKLKEQLALEQVVLTEDNLLEEKILDISDSKMETEDPNLNLGNDELKLNHFTFKKDVDGMEVFVGVISDVDLLKLNDQGEAETGLIEQHTDLINKIYRENRANVKKNCMSLTKYQQKLSLKPLFSSSFEDLPFFKTNIEKFQIIKPYIFQSIRRRILGVQKKKIKLLNQYKNYFNEWKVRAKKLELKQSQNYHKFMKKQRGLHGNLRQGNSIQNNFLPGGSEFLPNYYQQNNRGSRRGGLNTTDAVRSEAELESVLAMLAKENIDGDNERIAKNIPMAIDIYEKQALSYKDYNNLLPDTEGELNEYNSNAMIKWSKYEKELFLQKFLEFGKRFPKIAQYLPNKTSSDCIEYYYREKMNIGLKQLAKKHQQSQNKVGRRKGSQKKTKPVLLEHTSFPEEDVEEDVEEEDSTKKKKKEKNLASKTLGKYKSKADAEESEEDEGRGETAFDKSAGRQSLSVSDPKSLGKRTPRQVASIKSTNTETIANWSGDEKVKVCQAFELYGKNYETIAKVIGNGKKGEDIRLFYNKYKKTLNLQENVRKFDAKRKLEIVDNAIDGLGLKDTEKKIKRVKLDQNDLKDETAQDASIDVDESFIKNIAVGNEVNVTPISSTSEFFNQSQTLFPQPDSSQVRKTVSYWSVEEKKQFLLEFTKYGKNWDEISKHITAKSAIQIRNYYQNHKDEIGFDKYFVNSNNSLTGDDENQTDEVVDSRANITNTVEKVKRQYVQRKKRGSVHQTAFTHQQQHLLQQQQNTISTTSSVVGTVSASSTPAREEYGGWSNTFSPSPHHVNQQHIQQVSQVQHSKVNSNTFPPTFPPSSMTKSYYPKSEPSVNLFHQQQAPPQIQQQNPSIQQQIAAQPDYQSVTSSMPVSTPAITQNYYSGNYPTYRPAQNYKEFNSSSNTVNINSAVSSSSTRVQPSATNYFSTSDRRNSASSLNAKKDQVPAWRSGGFSYFTREEAAPRMTQDEFNMNHRLNEEFPKSTPNSNYYTASGSLFTPSTNESYRQHQVQSQQQQQTQSLQQRESQQQWGADYSYPQQQQKLAPIHNFVQQQFQQHTVRTPTPENVNISQNYASHSQQPVRMHTVDPSFQLAPISQLKQIISTRRDSTSSPKLPSSMILEKMSNGSSSPKLPNLSVLNKDNNSSPLHYSVEQQGIHGQMSGSSSPVKRLNNRGDETNFDRYPHLDSSASQNNPSAPGSQSNIMLLGGGLGAPGGLGSFDSSGFIKPEINNNLKSNSTLNSISLPSLSNMDYTTSSSSNPQQIVLPSLQNLLNLSKSGENGGGRGNSMNVVREQEVTKEDRYYSTYYVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSY7</accession>
    <name>A0AAD5TSY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ras- protein Rab-18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RAB18</name>
        <name evidence="3" type="ORF">HK099_002532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001843">
        <property type="protein sequence ID" value="KAJ3200749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSY7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001329">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3200749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="220" mass="25522" checksum="3A6FC8DE53098170" modified="2024-05-29" version="1" fragment="single">MDENIVASFKILLIGDTGVGKSSILLRFVDNKWSETMQPTLGVDYKIKLFTIENENYKLKLWDTAGQERFRSLTSSYYRNTQGVVLVFDVTNKQSLLNLESWRKEVEYYNSGVVTMIIANKIDQPERQVSREEGEMMAYNFGALYIETSAKTNQGIIDSFKELTEKIVERPSLWKNDNDWRRLTKQMSTNNLKSNKTAMPSLDRYNDSVNLKYGTEFSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT14</accession>
    <name>A0AAD5TT14_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002493</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001828">
        <property type="protein sequence ID" value="KAJ3200829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT14"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="385"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="413"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="151"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3200829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="452" mass="49542" checksum="DF6E65E8FAE907FB" modified="2024-05-29" version="1" fragment="single">MINLKPLQVSSNILNHDSVKLNDFSTSNSDKTSNLNHQTNDNFESLLPTTLLSPFFPNNNYNQKDLFFTSSLDNSLSPIQTPLTPISHSDDFSLSSDELKAHISTNDVLNYYDLLVNDMLRISTPALSPPPPISISTDNLNQVLNTSNSFHSPSTTTSFSSTPTSTTPFTSTSFSTATSSTPPFTSTLYSPIPTSTLYSPIPTSTLYSPIPTSTLSSQFSSISTSPPFSSAPTSPPIVDNSQSILRTTTPTNFYNANQNDFFSSNFTSTSDIMQDAILSSQTLEQQQQNFPPSNPIYPLRISPPLNTAISKAQSSSSLSPEEFLGNIFTNDISDPPSPSSSSLSETLMVIPTNTSNNNSKSDPASNNDLKKIKKNKKVINTNLPHKCPRCIATFATEYQLITHSIKHAEVRPFGCKNCSKTFSRHHDALRHVKNVHKVSREEAKNFTTDDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU54</accession>
    <name>A0AAD5TU54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001324">
        <property type="protein sequence ID" value="KAJ3204227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU54"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="97" mass="10946" checksum="8CC996F6D1E2DD24" modified="2024-05-29" version="1" fragment="single">NALENDDSVLFTLPTNDSNVNLNPHPTLPNFMFAVEDEEGETRDWNVISGNKTLKIMLLSYVGFGIVFVKYIVPDAYAYIVAFMMIFSVCLGLLLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU74</accession>
    <name>A0AAD5TU74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycerophosphocholine acyltransferase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_001307</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001354">
        <property type="protein sequence ID" value="KAJ3203981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU74"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021261">
        <property type="entry name" value="GPCAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31201">
        <property type="entry name" value="OS01G0585100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10998">
        <property type="entry name" value="DUF2838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3203981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="454" mass="52771" checksum="153B393B2E91118C" modified="2024-05-29" version="1">MTAHDCSNSSGTVIEDTSVSPVLSVRSNYSPALSPTLSAASYDEFLDFDDLSLDYDEDFLHLLFGISIRKRFQLLKDKARGKHAALKTNLIVKKSSLKKKLQQQKTVKLRDKFAFVLGVSNLWITPVLITSYPNFVPFYYAMITIPLIVLRFLLYRSKKWHYFTADLCYVVNFLTVLCLYAFPSSNFMFIATFCLAHGPVAWAIYAWRNSMVFHSVDKMTSIWIHYMLKELKYSHFAYNPKNELGTMEVSFIKSLLYSMAIYLFWQVAYYYFILVRKADKVFKGERATSFTWMLADYMKNKPDSPLTKLMVKVGEKYHVFCFMSLNFIYAILTTIPTFIFYKNFILHTTFLIIMLMMSIFNGADYYIEVFSKRYGIELTQLGSLNEEETLLEATFGCTSSRGKALKTEKPHKLKEENVDSNDIMDKILDKETFNISDVQRRLSVKDFSEEKKNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUI3</accession>
    <name>A0AAD5TUI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Peroxin-10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">PEX10</name>
        <name evidence="22" type="ORF">HK099_000638</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010001159">
        <property type="protein sequence ID" value="KAJ3206014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUI3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16527">
        <property type="entry name" value="RING-HC_PEX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23350:SF0">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="21">
        <location>
            <begin position="270"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3206014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="322" mass="37541" checksum="C79603C8DF1DF783" modified="2024-05-29" version="1">MSTFAEKVIDFDVTSEHETDDNHPSQLPNPLQTVSKDQAKKDLSSSENSANRIDILLNNFQRDQKFYRTRENRNLNTVKSTETRIFWFAVGESFLMILMACFQKVMQKSNFPIAPQPEVLRANQKDLYQISTLNSKISDLGKSLIGTRLYQSYNAYFNFLSNLLYYLLTTIPGNQTIGEEYCEIMQIENKNFQPVSLKIFTRKLQEIEESNSYEFLGFLILIQLMFNFNKLILGIFFPEKNLVETSMNDYKNENNLTDDDDDFTKESEKCNLCLSKRVNSTVTDCGHIFCWDCICEWSKTKRECPLCRQAINPSHFFLALNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV86</accession>
    <name>A0AAD5TV86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000495</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001112">
        <property type="protein sequence ID" value="KAJ3206607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV86"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008126">
        <property type="term" value="F:acetylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051792">
        <property type="term" value="P:medium-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051793">
        <property type="term" value="P:medium-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050960">
        <property type="entry name" value="AB_hydrolase_4_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794">
        <property type="entry name" value="ABHYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10794:SF63">
        <property type="entry name" value="ALPHA_BETA HYDROLASE 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="83"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="2">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005211-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3206607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="486" mass="54907" checksum="0BC1B3DEB944A08A" modified="2024-05-29" version="1" fragment="single">INNKLISIEDYVNKYCPNLTNSTFYPTIWLLGGHLQTFWAAFVGDNSKDRVKYEREILTAADGGTISIDWTPRLNELFSDESPILIVSHGLTGGSHETYVHDLLYEALFHEVPAHKRPDLENFENHPLTAKFRCVVVNFRGCANTKLTSPLLYCGAYTDDLRLVVKHIHAKFPKAKLCGVGFSLGANIMTKYVGEEGVNCLFSAFVSVANPYDLISGALAMHRTWIGRNIYSAKMNANLKRVLYTHKQILESNKYDIDAIAKSKTITDFDAALTSIAFDYLNVTDYYRKASSNAYINHIRVPTLLLTAFDDPVAHFETIPWYEVNHNGYVVLGVTKGGGHIGWFSGGNMFLSYLGPLIGYVKKEMNMKGAPQRWFTKSVVEFVNGIVNGVDESQFNKEESKTQDSKVKNPYTSQKLEFLPSPMSSTSSRIKRHLVDNDQLSHKKLKKSDNEENKKNLMDLEKEIISSNDFDLDNKENNNKKNLKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVC5</accession>
    <name>A0AAD5TVC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">thioredoxin-disulfide reductase (NADPH)</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TRR1_1</name>
        <name evidence="11" type="ORF">HK099_001885</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010001586">
        <property type="protein sequence ID" value="KAJ3202333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVC5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000064">
        <property type="entry name" value="Thioredoxin reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="10">
        <location>
            <begin position="22"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3202333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="247" mass="27071" checksum="FB5EC6391FC19539" modified="2024-05-29" version="1" fragment="single">TKIISETISRVDFSSNPLKLWREGSDEKDEDAILSKSVIIATGATAKRLNIAGEETYWQAGISACAVCDGAVPIFRNKPLVVVGGGDSASEEATYLTKYASEVIVLVRRDKLRASKVMADRLLNHPKCKVLWNKIPIEAKGDGRLLNQLRIKDTVTGVEEDLNVNGLFYAIGHKPNTDFLKDSNITTDELGYIKTFPNQGVPSCYTNIPGVFACGDVQDRTYRQAVTAAGNGCMASLDCERWLESQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVL2</accession>
    <name>A0AAD5TVL2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001701">
        <property type="protein sequence ID" value="KAJ3201606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVL2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="219" mass="24999" checksum="EC1A826EB9354739" modified="2024-05-29" version="1">MYTLLENLKLDNLKKETYEELKNKVDLLSLVIDEKGPFVSKAASKVKQVLSKNAVLDKPEIESLIQAERILKFQKIAQEEMRFELFHSPAKEIALNSTFMEEGAFTPTSLQTPMSATTARQQGVVKHSSTSSLDYITGGLRNKNNSQKAELIGFNNSTNDDDVIEEREIDVNESKMLLEHNKILQEELTDELSRLTYKLKSNAENMKNFLEKDKEVQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWV6</accession>
    <name>A0AAD5TWV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ANAPC2</name>
        <name evidence="8" type="ORF">HK099_000299</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001062">
        <property type="protein sequence ID" value="KAJ3207328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWV6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044554">
        <property type="entry name" value="ANAPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014786">
        <property type="entry name" value="ANAPC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057975">
        <property type="entry name" value="TPR_ANAPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45957">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45957:SF1">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08672">
        <property type="entry name" value="ANAPC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25773">
        <property type="entry name" value="TPR_ANAPC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01013">
        <property type="entry name" value="APC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cullin family profile" evidence="7">
        <location>
            <begin position="294"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3207328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="643" mass="75737" checksum="F06F552CD4670680" modified="2024-05-29" version="1">MDSYVFLNSLEDIIECKNLNYVEMIKNLNSLKSTLSNNNMWLGFIIQNETLKKKTLTFLLESYENEDLMFNESLIQQLQNVIAPILFQATSFVVNKKLSENKDVLLEEMRVTLNLKLLPFMKIINGEKKFNKSSQVRFESLMYKNIFQDRIEKIFDLIVDFPDSKSQLEDLKTVLEKVDGIEHFYDSLFSSTEKRLLHQGASTNSIIQQYLNTIKVLKFLNFDENLIEKLTSKIKIYILSRKDSCNLILNLILEGDGENLFQYEVETINKDNNKEIVIKELSDYIINIFDVHDFVEEFQKYISTRFLMSGNFNATTEIELFEILKLKVLRNKEIDDVHGINNIEVMIKDLGNSRRLHKMISEDQSIKFNHPFSTLVLSRLYWPKLQFENFNIDPLIKIDMETFEEKFKLIKAARKLQFLPSLGLVKLDLTFEDGRIENISCSPVQARVIMLFQNRDSMTRDELLSYTGLSENLLDATIFFWLKNQILINPDEDNFNLFKVNEYKSNNKQKKLYIDLADYLKTKEQKKNEKLSSTKKGKLRNLEEFIKFEKNYFQFIKGMLKNLGETKIEKIHSMLKIFFSKNNQEAEKFEKSIQELKPFLDYFCEEKISFLGGDETSVTEDHKEGESRLIFLDGKYKLNPNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXK8</accession>
    <name>A0AAD5TXK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000651">
        <property type="protein sequence ID" value="KAJ3214091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXK8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="127" mass="14991" checksum="9C06996E91007D25" modified="2024-05-29" version="1">MKLHDYKFEQYNHQLWHLNENFYKIISASNEQSENIYNKSDHSSFEEYCGNLPILPEMELIVLSKSIEKDQEIFNYSKKEFLVNLENILFHKLNAEKPLSTSLSAVPFFSELRRRVSNSNSSKKPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXY3</accession>
    <name>A0AAD5TXY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome maturation factor UMP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the POMP/UMP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000557">
        <property type="protein sequence ID" value="KAJ3215236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXY3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008012">
        <property type="entry name" value="Ump1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828:SF3">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05348">
        <property type="entry name" value="UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="15275" checksum="76EE66203A9237BC" modified="2024-05-29" version="1">MHLTSTEKQAQPTLTLGSATTFGVNDTMRYGLVTASDKLMKQHPLKMHLQQAASKKSELQIMRNIYGLHAPLRLKMERAILNQPHRIPVMKNSNFGLNTLNGSYMDINFEDFLGDQEYCTDSLDVHAAMEHTLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY13</accession>
    <name>A0AAD5TY13_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006365</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000541">
        <property type="protein sequence ID" value="KAJ3215468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY13"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000003">
        <property type="entry name" value="membrane-associated progesterone receptor component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018298">
        <property type="entry name" value="Adrenodoxin_Fe-S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426:SF65">
        <property type="entry name" value="FERREDOXIN-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="FERREDOXIN/ADRENODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00355">
        <property type="entry name" value="ADRENODOXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00814">
        <property type="entry name" value="ADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="248" mass="28052" checksum="CCF838765F64F09D" modified="2024-05-29" version="1">MDIAHANDIDLEGACEGSLACSTCHVIVEENFYDKLEEPNDEENDMLDLAFGLTETSRLGCQVEMDEELDGIIVKIPALKAKIQKKKMSQAEFYAKQLSENPLNWILLTVAVYVSMSLFSVNSHSHRKIVELKHPETILIRNFTRKELEEFNGENGKKIYMAVAGKVFDVTSGKSFYGPGGMYGNFAGRDASRGLAKNSFDKEMIKSLSEPIDNLNDLEKDEIESLKEWAAFFEQKYIHIGFLFEDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYD5</accession>
    <name>A0AAD5TYD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Kinase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007672</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000765">
        <property type="protein sequence ID" value="KAJ3212715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYD5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004703">
        <property type="term" value="F:G protein-coupled receptor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000354">
        <property type="entry name" value="AGC/YANK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000469">
        <property type="entry name" value="Serine/threonine-protein kinase 32B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355:SF30">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 32B ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="284"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3212715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="49128" checksum="39FFA770C5627DA2" modified="2024-05-29" version="1">MGQNCCKEEEINFDGEVELMHFNLLRSVGKGAFGKVRVVQHRKSNSIYALKYINKAQCIKMKAVENIIQERRLLEEISCAFVCNLRYAFQDEENMFMVIDLMLGGDLRFHLDRQGQMKEEQVCFYMAELSYGLSILHSRKIVHRDLKPDNVLLDDAGHAHLTDFNIAVHFREDKPLTAVAGSMAYMAPEILAKKGYLSTIDWWSLGVMMYELIFGNRPFRAKTNEALTNAILGDDVYIPSQATSICSQECIDCINAYLTRDITKRLGVKEMGGYEGIKAHPFFKKINWVELEAKKATPPFVPDAKRANFDATHELEELLLEDNPLKNKPKKKKNGELVPTKLSDDPVIAKAMQTMYEKFTVYDYTKNDMNLGIAVDLKDEKSLAAPQMRKVKPGVPGEESMLSIHKDVMEGRDEEVNNVGLESHLSNVKSAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYQ7</accession>
    <name>A0AAD5TYQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL19_2</name>
        <name evidence="6" type="ORF">HK099_006518</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000569">
        <property type="protein sequence ID" value="KAJ3215093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYQ7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="5">
        <location>
            <begin position="14"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3215093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="225" mass="25891" checksum="FC0316702E95EB4E" modified="2024-05-29" version="1">MSMGRAEPCSGVVNLTTQKRLAAAVMKCGKRKVWLDPNEINEIASANSRQNIRKLKKDGLIIKRQDKATSRFRVREKLAAKRKGRHMGIGNRHGSADARMPEQVLWMRRQRVLRRLLRKYRESGKIDKHLYHQLYLKSKGNVFKNKRVLMEYIHKAKAEKARSKTLADQAEAHRNKARAVRERRAARLQAKKDELFGVAEVKPTETKVVTAEVPTTKSSKKTSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYU4</accession>
    <name>A0AAD5TYU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000454">
        <property type="protein sequence ID" value="KAJ3216907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYU4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042165782" evidence="2">
        <location>
            <begin position="20"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="139" mass="15877" checksum="43159146358F9CAC" modified="2024-05-29" version="1">MKFTQLIVLVATLSNFSSSLFIPQLEARQSNLQGFHSPAAGHKVETVERRQLGRLGFFIPPKGIHNDENPDKKKRDTDVDLEIGIEKRQLGNLNIFFNPGKGGDEEPVDKKKRSFPEDYENLKDFKFEEFMDGNVRVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYY2</accession>
    <name>A0AAD5TYY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005592</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000442">
        <property type="protein sequence ID" value="KAJ3217136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYY2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="319" mass="37207" checksum="7838F6D2D050B1D2" modified="2024-05-29" version="1">MANNEKSYKQIDILDELLSSPEIENKKFSELVNPLRIAYINGHYALRILNSQILDARFLLQKIDTNPNTCQLKKLIMLTTNRFDFGLDGTDKADYYALIGRLNANQPKRVIWVQNNPWENRYMLLKMGPNTVPKPLLVRPFGFSSLQVTNSLPYNAASSACMYSHPFIEKFHEKAAKAGVNLVKLGWQYGGPTVLSKFKVFVDLPYQTSTMKMYENMAHGVVTMVPTPRFIRENLIPDTATVNFVNLYDTLKVGDDWFKYIEYFNDDFKEYFPYQFDSLEDLKFKIENFNDTFNIREKLPLAWKQENAKSLKLWKEVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZA0</accession>
    <name>A0AAD5TZA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000677">
        <property type="protein sequence ID" value="KAJ3213773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZA0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="100" mass="12109" checksum="B5E71FCC7EF13BB4" modified="2024-05-29" version="1" fragment="single">LNEIEGIKGELEKDDLIKIFKSEIKFSEKKKNVQDIFYKLNLLEKNLWQQKNLILNLNNKYVGYLDNYNEMINNVSELFIFYHKLLNDIEKEVIRLENKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZH3</accession>
    <name>A0AAD5TZH3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exosome component 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">EXOSC5</name>
        <name evidence="7" type="ORF">HK099_000340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001076">
        <property type="protein sequence ID" value="KAJ3207152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZH3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3207152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="139" mass="15575" checksum="C74010DCE26FC41B" modified="2024-05-29" version="1">MEKILVDICEYLILSTLNPRTLIQVVIQPIQDQGSILSASVNAMVLALINAGIPICSIVSSLTCCIDQEGELLVDPDNSEIENAQSVHFFTFDCKTDEIVVSDSYGSTAAEEMFVNWVVKKFNYLLEWQLKKDYYTNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0F2</accession>
    <name>A0AAD5U0F2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Anaphase-promoting complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">APC1</name>
        <name evidence="9" type="ORF">HK099_007095</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000660">
        <property type="protein sequence ID" value="KAJ3213973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048971">
        <property type="entry name" value="Apc1_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041221">
        <property type="entry name" value="APC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046794">
        <property type="entry name" value="Apc1_MidN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21282">
        <property type="entry name" value="APC1_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18122">
        <property type="entry name" value="APC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20518">
        <property type="entry name" value="Apc1_MidN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 middle" evidence="7">
        <location>
            <begin position="757"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 beta-sandwich" evidence="8">
        <location>
            <begin position="1500"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 C-terminal" evidence="6">
        <location>
            <begin position="1632"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3213973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1811" mass="206574" checksum="77A7836CBF1864DD" modified="2024-05-29" version="1" fragment="single">LENNSLKKLKNQKILFITESLGESGVGFNLIITYDYVALKHKFWLVEYSEDFLRKFKGSGFHSKKSTILESNNDQEIQLKVFNEEFFNNDYLILSDTPNSSNFSTFSKTKKSAQDKENILDSALNEENDSDDEMEFKSKIFNQSRTIFNLLWEQDLNKTEFFPMCEAADKVVIGDSSKGSKIIWFFKKSSKVAYSLKLSKKLNKIEEGGEFEVGNISSEMKDDYNVHFFCKKSCLDLISINSTRKLLKDVLFLLPDSTLHLWAGDEKICLFDNEEPYFDQLFLTVELPENFPNINYNQKFQSFNRKRNFTSDLKFNTLEETTSNLFVSPSKISRLVGFSDSVENHLNFQFSDGKVFRAQLSFFPLSNLVQTCMEVFDVILPSEVGFQFKSRFLKYQFGGSGIRDGSKDLKNEDDVQFDNFRKENNEFDNFIITLFSFFHQKPTIKKSNLYNCSSNSENPSDHDFQTLMTSDLHEKFRIDPSLKFLNAELNSFKKEKHNSKYINFEKTRMRNFFEISKELNLKYLIKKSFNRNSLTNSEDASSGFLPAADSRKFEVKNYFQIIFFGLHLVYEDLKLNLVSQKDLKSLGNFLIFFSKRFKYRGEGNGATKNGNFVFDNFFKAYLFDGLKFVDEDFSFEVADSHIALPESILRNPPNIYKGLLFLINGKINKDNDSCNAPVEKVASTDKHLDLAYFDIKAFGLNLNRIYKSYLNEKSDVLNLDAVANTTALQNTNLILHFFGIKFKCYPEDEKKKIEVDAQLVNAMVKIGFKLKDIDCLPFGVALPLRESIKECRNNPPQFWNVEEYTMIGRDDLAQQFCGKMQSSPYSPVISAEIRLEKPVEVGALIENILISTNTTPVVDAEEKNISNNKLVKLIFSKNNVIKEALNLFDIEKIISLEQEVTPDISEQGLIDAQQAVLLNLSKRSFAMALGKAMINFSSVTPLLTESIPISDILIQAKLPPLNSVVQLDMTNLQSDLMDWPLFHQGVAESLKIPLSKSGFKIKGSWIFFNQDSPDSCKHAGFLYAVGLLGHLKTMEEWRKFLYLVPKHKPTAIGLILGLAASYVGTANESVSKLLNIHIPALLPPSSSELNTSILIQTSAIFGIGLNFLGTSNKKMVEVMLNEIGQRKIEDFDDSKIHEITSHEGYSLAAGFALGFITVGIADKDPHLADVQIVNRLVRMISGGHFEPCVVTYDALLKKNMEKNLPSNFQQQQHAQSQSQEHSQCSKNEYKLLNVDVSSPGATVALSLMYLRSNNQMIADKLNIPTSQVLLDYCRPDFLLLRVIGRNLIMFDQMEPSINWIRSLIPSFIYNSVSFQFTQEFENIEETKKRTECDDDSVEHAICNIIAGACLSLGLKYAGTAHKAAFEILLKWVDFFIKHASKPAVTFSEKFKRTILRTCLDISLVSLGVVMAGTGNSKVFERACQLNARLSSDITYGNHLATSMTIGFLFLGGGRLTLSTSDKSIACLFCALYPKFPISATDNDFHMQAFRHLWVLSVSDRCLVTRDVYTQEPCCVPVVLEIRYPGSRGSLLKKSERISLVTPCTLPEISSIVSIEIDSCRYWPLKYSMKFNKDLFVKVLKFKQLFVKRKMGYLDYMQDPKGQKSVLASPFPNLFSTSEFNSENVYAQKDMEEFIKSFSQDPITLSFANNFCCLPRKNLTLKSYDMAAFCTSVLYDCLTQDKPEIIQTYLSIYQTVLQVLEEQGHGFREDDNQGQVLSIWNLKLVFENYANNFQASERFDNFEENISRKKLPLIQGLFLNNIKYNIDFKILEGKKDKQSLMVKNLENYIRNEECAQLSILFLIDYIFNCTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0F9</accession>
    <name>A0AAD5U0F9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleolar protein 58</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MGM1</name>
        <name evidence="16" type="ORF">HK099_006299</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for pre-18S rRNA processing. May bind microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000534">
        <property type="protein sequence ID" value="KAJ3215565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000003">
        <property type="entry name" value="Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000001">
        <property type="entry name" value="Probable Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056495">
        <property type="entry name" value="LIS_MGM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24550">
        <property type="entry name" value="LIS_MGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="13">
        <location>
            <begin position="285"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Dynamin-type G" evidence="15">
        <location>
            <begin position="667"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="14">
        <location>
            <begin position="1209"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="405"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="594"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1108"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="610"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3215565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1301" mass="146662" checksum="901A6C1BA461F3F9" modified="2024-05-29" version="1">MLVLFETPAGYALFKVLDSKQIKDADKIEKHFETPEGANKLLKLKAFQKFENTTDALSAVTGLVEGKISKNLKGFLDSELTDKDLLDKLAVADTKLGSAIQKKFTLKVVSDAATFELMRGIRSQLDSLIGDGLSQTDMNQMVLGLSHSLSRYKLKFSPDKVDTMIIQAINLLDDLDKELNTYSMRAKEWYGWHFPEMTKIIVDNIAYAKCVKAIGFRTNTASTDLSSILPEDLESELKQAAEISMGTEISDQDIENIVFLCDQVVSISEYRAQLYDYLKNRMAAIAPNLTAVVGEIVGAKLIAHAGSLLTLAKYPASTVQILGAEKALFRALKTKHDTPKYGLIYHASLVGQAAPKLKGKIARTVATKAAISIRVDALGETENANTGIEQRAKVEMRLRQLEGKAVTKTNAASTKNQTKMKKFEKNPTSSYNESSDVVLVKKVKQTEITEEIEEVEKPKKKKEKKEKKEKKEITETVEITSHVGKKRKADDDNVEKKKKKKKSKSENVFSFTRIIFSVTRLPLFLGVTGASAVGFISYKIEEFKEDYIPEWLKNSVHDTTEYIKNFEFPELPELPTLPELPSFPFFKLPHHDTDPSSTSNFFSDDEENKSNVTARQPPAEQQVTMNKSEGYNGNSQISAPDHELMVLTKKLIEVRNLLKDVNIQNETLKLPSIVVIGSQSSGKSSVLESIVGHEFLPKGKNMVTRRPIELTLIHSPETKEDFGEFPQLGLGKIFDFSHIQKTLTDLNLAVTDEECVSKDPIELFIHSANVPDLTLIDLPGYIQIHNRHQPAELKKKISDLCETYITEPNIILAVCAADVDLANSPALQASRKVDPKGSRTIGVVTKMDLVDPDDGLRILKNKEFPLQLGYVGVSCKPNTSVSLLRRTESLSSVYAKSNVKVGTETLRTTLMQVLESHMGKSLTGIVEAVQAELDDARYHLKVEYNDRRISAESYVAGVLDTLKTKFKEYENSFGKPQVREHLRDMLEKQIFTILDDIYYSNPEEIQQIFKTCTNEKIYWEHKLDLASAALTKSGLGRGSTQLVVDILMKKMEELTNVEPFIHHADARKKILATSNDIIKSKFHTTVDQVENTIKPYKFDVESTEAEWADGLRRAITMLEKKLKESQNEIQEIRGTLGRRKLRQALAHLEKKEKDQKFSPQKLPPATTAEEEELFPKNILLKAKKFLTLNQQQQILQLRISNLKSRQCRKSNKGCCPEAYLSMVSEKLTYTAVMFINVELLSEFFFTMPRELESKLYYGVRGNDVIKFAEENLVVKNHLHSLKRREILEEVMGKLKELNKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0N3</accession>
    <name>A0AAD5U0N3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein RED C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000316">
        <property type="protein sequence ID" value="KAJ3220060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0N3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039896">
        <property type="entry name" value="Red-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012492">
        <property type="entry name" value="RED_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12765">
        <property type="entry name" value="RED PROTEIN IK FACTOR CYTOKINE IK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07807">
        <property type="entry name" value="RED_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein RED C-terminal" evidence="2">
        <location>
            <begin position="92"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="192" mass="21997" checksum="4F3EF3CACFE8FA5E" modified="2024-05-29" version="1">MRIIFADVGRDYELSKPSAEKEVAKIKSDSYFDSMDIEEEEKKIDLKETFNQAGISGDLFVSNPAVLGKGVKRTRRIQEDTYGYGEEYGESFGFNDDEEDELEEEEEEAVALVDQGTKKNRIKQKTRFDFETEEEFAAYKEKQIHLPKAAFNFGVKVKDGRKNVTSGKSGKKIDTKDKQNNEFQKISKMMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0P5</accession>
    <name>A0AAD5U0P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000465">
        <property type="protein sequence ID" value="KAJ3216681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="90" mass="9919" checksum="53C2B3E25065D259" modified="2024-05-29" version="1">MELFTSKGRLYNNTPPSSVLVQQDTNFDDLKGLIKVEYSNNLSHIDAGQLEIYESVDNLAKVPIALDTPVTGLGTTLATRLWVVVPLPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0U3</accession>
    <name>A0AAD5U0U3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007809</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000797">
        <property type="protein sequence ID" value="KAJ3212068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0U3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3212068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="286" mass="32895" checksum="884FB45175159787" modified="2024-05-29" version="1">MNSTNFLDNFVNKKLICSTCYANCSSGFSDLIKKNPLPFNNLRSSFKDCFCRDMLNVILGNSTVCGKQYVTSTDNCIKNLEGYPIPDVELHYESCTLTPIPDEFFVHYRIKLATNESLTEPYMPEEQKKNFDYRPFLFLFIFALLLAVLVRWKFNAVLMRPPPNINPTIPSNVVIPLNERSLYYYQEEFGDEQLPKYTKDASDFDYQPFNENISLQPLHSSSNTTTTIPPLPTFEESQFSTQRNVERGEISIETQQNVDSEITERNETSVSIPLTSYEQIANSDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U152</accession>
    <name>A0AAD5U152_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003844</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000258">
        <property type="protein sequence ID" value="KAJ3221007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U152"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052427">
        <property type="entry name" value="Glycosyltrans_GT2/GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844:SF1">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47844">
        <property type="entry name" value="SYNTHASE CPS1, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G02500)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13641">
        <property type="entry name" value="Glyco_tranf_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3221007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="354" mass="41791" checksum="34C8070BDC030905" modified="2024-05-29" version="1" fragment="single">RVIPLNKNFTIWEILASYRLSLRNIEITASTYIDGGVCCLSGRTAAYRTLILRDPDFQTKFANEYWLGKYHCHSGDDKFLTRWLHSHEWKTYIQACPEAELASTFKDNWRFLKQLLRWTRNTWRSDLKSLIVERKIWRRYPFVAFSMLDKFFNPISLLAGPITVGYLCSMPNGYLPTWVVLTSYFIWLILTRLIKYIPHFINRPQDVFTLPIWIVFNIYFALLKIYCLFTLHIVDWGTRVGADDQGEKEEDDSEIFLVKNEIVDKSKKINLKSEEDEIKKITEKEKVKTKELKKEKILRLNREMDIERGLNNAIEIEEKLILNSNYVDNSTHLSLSRSKTSIQVNDKIVENGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U174</accession>
    <name>A0AAD5U174_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000278">
        <property type="protein sequence ID" value="KAJ3220724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U174"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15840">
        <property type="entry name" value="SNARE_Qa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000059">
        <property type="entry name" value="Related to syntaxin 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF38">
        <property type="entry name" value="LD27581P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14523">
        <property type="entry name" value="Syntaxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="176"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="214"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="377" mass="42790" checksum="1457F362CD54D25E" modified="2024-05-29" version="1">MSFNNPLGVNSSADSTSTIDSAFQFDKCSKALFTISNNIQQLVQTSQSINTPKDSHSTRESLLALQEETKELIKLTSEDLKVVLSLDSDEISIKTKKKKLEKDFKNIAKRFQQVSKVVTEKCRDSLKTAKEINELTLSRVELEEEENEGVPLLAESNSKKKLVELKQMDNQIDYNENLIQEREQDLRQIESSMLEVNEIFRDLGTLVHEQGHMLDNIENNVDSVAINMENATGELRTANEYHKKARRRAFCLTVVLAIIGFVKHMDKDITAPLIPRKVGKPVAFENLTVSAVQKTKATFANLSSFLSKRVETEAKYSKLKVSFDDTVNRINLINVVDRKGTSPSILTKAEIEEFKFFLVQMRLGNTIEREKKVSKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1I8</accession>
    <name>A0AAD5U1I8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="7 11">3.13.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SAH1</name>
        <name evidence="14" type="ORF">HK099_003681</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.13.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="10 11">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.13.2.1" evidence="7 11"/>
    <dbReference type="EMBL" id="JADGJW010000243">
        <property type="protein sequence ID" value="KAJ3221229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1I8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033353">
        <property type="term" value="P:S-adenosylmethionine cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1480:FF:000004">
        <property type="entry name" value="Adenosylhomocysteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000004">
        <property type="entry name" value="Adenosylhomocysteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004005">
        <property type="entry name" value="PRK05476.2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420:SF0">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10 11" id="KW-0520">NAD</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S-adenosyl-L-homocysteine hydrolase NAD binding" evidence="13">
        <location>
            <begin position="192"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="158"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="223"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="300"/>
            <end position="302"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3221229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="433" mass="47166" checksum="9C7F69053B678567" modified="2024-05-29" version="1">MTSHKYKVADITLADFGRKEIEIAENEMPGLMNLRAKYGPSQPLKGARIAGCLHMTIQTAVLIETLTALGAEVTWSSCNIFSTQDHAAAAIAASGVSVFAWKGETDEEYNWCIDQQLKAFKDGKSLNLILDDGGDLTTWVHEKYPEALTGVLGLSEETTTGVHHLYKMLKDGKLKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVSVVAGYGDVGKGCAAALRGMGSRVIVTEIDPINALQAAMEGFEVTTFDKAVAEGNIFVTTTGCRDIIVGRHFEAMKDDAIVCNIGHFDCEIDVAWLKANAKSVSNIKPQVDRFTMKSGRRIILLAEGRLVNLGCGTGHPSFVMSNSFCNQVLAQIALYTRPKEFPLGVHLLPKKLDEEVAAAHLDKLGIHLTKLSDVQSEYLSLPVDGPFKPDHYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1T9</accession>
    <name>A0AAD5U1T9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_003432</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000225">
        <property type="protein sequence ID" value="KAJ3221520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1T9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF3">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="8"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="96"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="275" mass="30799" checksum="926C487B4065FC05" modified="2024-05-29" version="1">MSKSVDDIVFFRELKAAIFSAIAARTLTHPLDTIKTRVQNNSINLSNSWSSLYRGLSVALCFSVPAVSGYLVGYDYVKSFLSNKLLHSDNNHSIFRLLLVHSTSACFAEAWSGLLWTPMEVVKQKMQVGKSPSSSTLQMMNKIYKREGIRGFYNGYFVSLGVFVPYTVMYFVTYEQLKIRAFKFFNKDESRGEKLSPIVYPIAAAVSGALSAAVSNALDIVKTRIQVGVTDSKLKNDLNQSNLKTFLLIRHMWTNEGGLRAFARGMPQRVAYLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Z9</accession>
    <name>A0AAD5U1Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">BCAT1</name>
        <name evidence="12" type="ORF">HK099_004760</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="JADGJW010000346">
        <property type="protein sequence ID" value="KAJ3219242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Z9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004084">
        <property type="term" value="F:branched-chain-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000005">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF44">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3219242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="405" mass="45457" checksum="F99A9869329E445D" modified="2024-05-29" version="1">MIVTKSRLLTSILKPQSKIAFPSTLLNVRLKSSTALPDIDSSKLKVTMNSELKKKPLNKDLLFGHSFTDHMLTVEWTATKGWEAPKILPYGKLSLDPSAVVFHYAIECFEGMKAYIDKQGKIRLFRPDMNMNRLASSCKRLTLPAFDRKQFLECVKELLKIDKSWIPKEKGYSLYIRPTAIGTQNSLGVGPSNKALMFVICSPVGPYYKTGFSAVSLYATRDYVRAWPGGTGDAKLGSNYASGIRPQIEVAKDGYQQILWMFGKEDYVTEVGTMNFFCYWINEQGEKELCTPPLDGTILPGVTRNSILSLARDWKEFKVVEKNITLPEIKKASTENRLLELFGAGTAAIVSPIKNIRYNDFDIKVPLDPKDPKAQAGPLTTRFAETIMGIQYGDINHKDWSVVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2C4</accession>
    <name>A0AAD5U2C4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004094</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000280">
        <property type="protein sequence ID" value="KAJ3220693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2C4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="202" mass="23172" checksum="7538D7E985748D4E" modified="2024-05-29" version="1">MFDICYIKLFNEEQQPHNSIKNSLIISNELNQLNFGKQNAIFQADSSEDNFMNEMKNDSLSANNVCGTSKKLPGNLHLSDIYTEYGYSPVPVNSLLPYSNQALLSNSRTSSPTQQKQSIFSSGEIIDLKIQGDPTTEEEIRNSIHACLDCSKTFRRLQDLRRHKANIHERIILNTCKHCAKKFTRSDALFRHINKKRCKEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2F0</accession>
    <name>A0AAD5U2F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002727</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000193">
        <property type="protein sequence ID" value="KAJ3222073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2F0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="168" mass="19810" checksum="4B685E1ABD0616EC" modified="2024-05-29" version="1" fragment="single">THLSNVLSKQTQELLSTTTPDQYIRVLHKQLQDMLTALHDCLDALAEETRNTERWRLKYEKYQKFVEKNYELKFKSASSFNNLSDINNQIDLQKRNKILSCLKFPSVNESVHKNILKLSKIKNNNKFGFLNDDDFNLEKESEKNFSRPKYIPESERNIVKEALVIKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2P1</accession>
    <name>A0AAD5U2P1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000289">
        <property type="protein sequence ID" value="KAJ3220592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2P1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="173" mass="20129" checksum="175377143620D698" modified="2024-05-29" version="1">MNESFVYDNEAPTYGRSFEGQRILRPRKRHGESWTFFLAILLNGLVHNPLISTENAREENFLDYVRNTLVPHPQEGEVVLWDRFEAMVLIVSKGARIIFLPPQVKFFNPVKLVFGTVKLTFEIHTNYTIARTEVEVRSIVKESCDKITETAIEGYFRERGGGREFKRLYSDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2W9</accession>
    <name>A0AAD5U2W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NPC2_1</name>
        <name evidence="4" type="ORF">HK099_002204</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000171">
        <property type="protein sequence ID" value="KAJ3222531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2W9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042292416" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="3">
        <location>
            <begin position="30"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="158" mass="16979" checksum="4348DC1C6FCAC32C" modified="2024-05-29" version="1">MFVKSVVSALIIAVASSKVIYDVASPDSQFKFCGTANDALDLKKVEMNPYPPVPGQNVRVTATGTLKRVIQDGAKEAQVNVLGKKGIFKIDRIVKTCTAESELKCPIPATLPGEPDLVQSYDYLVPAIPSFIKDIELTVSAVNGDESPVTCFKGPVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U365</accession>
    <name>A0AAD5U365_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Dihydropteridine reductase</fullName>
            <ecNumber evidence="14">1.5.1.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Quinoid dihydropteridine reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">HK099_001799</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.34" evidence="14"/>
    <dbReference type="EMBL" id="JADGJW010000155">
        <property type="protein sequence ID" value="KAJ3222875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004155">
        <property type="term" value="F:6,7-dihydropteridine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd05334">
        <property type="entry name" value="DHPR_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000157">
        <property type="entry name" value="Quinoid dihydropteridine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022226">
        <property type="entry name" value="DUF3752"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF11">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12572">
        <property type="entry name" value="DUF3752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0783">Tetrahydrobiopterin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="93"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="244"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="395"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="18">
        <location>
            <begin position="552"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="19">
        <location>
            <begin position="824"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1567"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1684"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1567"/>
            <end position="1615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00039153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00039520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00041348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3222875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1713" mass="193094" checksum="9197EF640057939E" modified="2024-05-29" version="1">MVAVKRFLLFKTKKITAQPSKLSKSTTVLSHYVNDKPVLDTTDSDLSTLESSTAEPDIELKKVNFVNVKSEHHETILRNGGDSIKVFLKEHVLFKGLDEEFIELLSTSMQIRVYNDMDYVIKKGEVGRAMFFIKKGIIEVISEDGEMVINVMKEGFFFGEIGVLFSVPRTATCRSNGRSIALILTKEKFAKAMAACPQAARVISLLAQERFSSYIKQQESKVEIDFGDELNMAVTKDDLQNVPLFRDCQVGFLHMMAMSLKPVQYKQGDYIIKKGDIASEIYFVARGTAQIINEETGQSFADFQPGSFFGEVGILFEVNRTASIVCSSSIINVFKLTKVDMDKLLDLFPEVAEKIKLEAKTRFERHKNTLASLSKNQEFNVEIEVMRERLKLVPIFSDGSVGFLHQLALTLRLRKYKKDEIIIQKDTIGSSMFFIFDGTAVVINDTGNEIYAELSNGSSFGEVALFYDIARTATVKAFNDISLFELAKESFHLVLDAHPKFAKTLNSIAAENYNLFLERQKAVKQLTRRSNSKKAVAYDVEATAARLKAVPLFSNCDSHFLHSLALNTTIQSFVKNDIIIQKGTKSSSMFFIVEGESLVVSDDLTQTYDVVKEGGFFGEVGLVKGILRTATVKVSSDICVVLILLEQSLQNVMLSSKESYQAIVLESARRYDLFEKRNNDTFALPEETTESMLKKRSLLNNSAFRTLKKVLTDIPSKTKSSNFVFETSTSKLKGINKYFSFKDSSSNDLQNNSELRMKKSSDSLEKGRILVPSSISSTDNEKAFLPMPELRCAQSVSSSTTKSTIKSDKFFFKVSEHKFNRQQQASILHLDSYILYLIYNNLKFLDQLKLRSICKQWKEEFSAGPYWEKLIFNSMYRTLTKQILKHFCEISGSSLCSLELKNCFRITDTELKGLSLTCRNINDLSLLNCWTITDKGVRHIAKNLTKLKSLDLSYCSQIIGVGFYNHQWTGLKKVDLSFCKLIGDNELEILLSKATEMKQISLRRCSKITDFGLFLIVRYCRVISSIDISDCNQLAEKSLKIITSGCSLLTSLNLTFCTKISSAGIFEVVLASKNLTNLTLNHCTQLTENSIISFLSKATKVKYLSIRGCKTMTDAGVIRLIRCSNGLKEINCTACPDLTQDLIVAVKNINPCIKLTMDKPAPKNIGKKKAGAKKIAEIPLSERFTNLPRKNLNKNVKALDKNKVDLYNIGIKSNLSLKKVAYTQWSRHVLVYGGCGNLGRTIVSKFISNKWMVTSVDFKDNSDATNNVILTSTPTFEEAGDYVMEKVRSFPKFDAVINVAGGWAGGSVNDKDIYNNVILMHNQSVFSSVIAAKLAASYLNEGGLLTLTGAAAATNGTPDMVAYGMAKAAVHHLVKSLALPKSELPNDSHVNAILPVILDTPMNRKFMPEADTTTWTPMDEVAQKLFSWASDKSLRPAKNGSLVKIVTVDGKTNFSEFNVQNKFDADISQLPLNQYQDLSDTNDNQFGPLLPPGFKKKKKVIKVVEESKKVKGPEIPDHLKKKFSEEVDDDEEDDIFGPILPKNYSKEQAEIDAYQQKLNKIEDRIANKKTENGGSENLKKLKRVGDTRSRQFQRHAKEIITDRSDWTDSPEEKLKKLQNPLKKEKKKKEEYLDIEQKKKQDNFLEQYNSERKSLVEEYTSNYLKDKKFEADEVKKRGFDREKDMTSFRLNPEKKQKMLNESKLLDSKFKKSYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3L0</accession>
    <name>A0AAD5U3L0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rad21/Rec8-like protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000135">
        <property type="protein sequence ID" value="KAJ3223323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3L0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="368" mass="41717" checksum="7D060D20EAB06793" modified="2024-05-29" version="1">MHQTSAIFPNPSLSIVWLMATVGRKSISKKQTESISVSKVLISRILIKSLCVHLCKLKVCQIITKDDKIQLRVKSSLLLGVSKVLLNQYQFILNDIVKLHSSLKQPQLQINLISPTEHQLKNLLLPYQNEIEKEFIFNFKSSKLNSFSKEFTSMSSLTSSPITGFNPKDGQLSKKNLNLTSGTGSQNLKLLDNTVVSCSVSAFDSNSSANLGQQDFFDMVSVEHEVNPDISRSEGMAIHTSWELDLGVENSQRNIEIEEMTGQPEDLIREFLKQPHQDKSLDSEEQPSILTDFYESIPEDETKNENIKTVKVTKKKKNLSLIDEKIELSREEMMIPTLFLPDLGVKLFRSPVLQLFQSERFKSERPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Q6</accession>
    <name>A0AAD5U3Q6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_001157</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Q6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="235"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="110"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="260"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="138"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3223433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="380" mass="44043" checksum="38E7147BD49A970B" modified="2024-05-29" version="1">MAQARLERINLMQSPSPVAFNQINKKNSMDNNQISQSEQYSQIQHFHPSPITPPLTQLHDSPQFHHETTQYLSDNSPQFNTENPIIPENFTIVNEREYEAAVFRSQTPIYHHDTPRFQPDFRSYSPANSDIQHHHQQQHQQQHQQNSLFNSTPSSILNTSNNNNSSNNISNNFRSDNNISPINSPIKKVKKSPPLQTSDPNRSRNYECDGCSKKFFRTQDLKRHKVTHNKDIRPFACTSCTSTFTRADALQRHIKKSRCRINSQHRSAKAVQQQQLQPSPQSQQLQLQQELPHQQDRYNQSFHSQASMQQQQQPMAQQEFINLKADYSSLQQSQSSTSQNNNEHHSYRPSIVQQNDQIYHPISQQDSNVMSLNNIQNILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3W2</accession>
    <name>A0AAD5U3W2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear envelope morphology protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NEM1</name>
        <name evidence="3" type="ORF">HK099_000939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3W2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000093">
        <property type="entry name" value="NLI interacting factor-like phosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="67"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="241" mass="27798" checksum="408E60C1BFC80B4E" modified="2024-05-29" version="1">MSSLLSSSFEDSSPISSYSNNLKKVIKKKKSNLSKLKENEQHYQTNSDSGTESSSTNNNLIKRYKKPSFKLKTLVLDLDETLIHSTSRMASRKHDHMVEVLIDKHICMYYVYKRPHVDYFLQKVSEWYKVVIFTASMAEYADPVIDWLDKSKTLISSRYFRQSCTLMRGVFLKDLTVIDQDLSNVCLIDNSSASFSLQMDNAIPIESWLSDKNDVALLDLLPFLEALRFCHDVRSILSLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U482</accession>
    <name>A0AAD5U482_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Phosphoacetylglucosamine mutase</fullName>
            <shortName evidence="14">PAGM</shortName>
            <ecNumber evidence="4 14">5.4.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">Acetylglucosamine phosphomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 14">N-acetylglucosamine-phosphate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">PGM3</name>
        <name evidence="21" type="ORF">HK099_000681</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23804"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="5.4.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14 17">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="4 14"/>
    <dbReference type="EMBL" id="JADGJW010000117">
        <property type="protein sequence ID" value="KAJ3223788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U482"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004610">
        <property type="term" value="F:phosphoacetylglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03086">
        <property type="entry name" value="PGM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000003">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000013">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000023">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049023">
        <property type="entry name" value="AMG1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016657">
        <property type="entry name" value="PAGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21405">
        <property type="entry name" value="AMG1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016408">
        <property type="entry name" value="PAGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 14 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 14 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="20">
        <location>
            <begin position="184"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="19">
        <location>
            <begin position="301"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="18">
        <location>
            <begin position="469"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="15">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="17">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="379"/>
            <end position="381"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="513"/>
            <end position="517"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR016408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF21405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3223788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="663" mass="73741" checksum="02597AA135621E03" modified="2024-05-29" version="1">MDFTSVNQLNQKYQKHDSTNFVYGTAGFRTLASTLCPVLFRLGMLANLRSRKLNSKIIGGMITASHNPFPDNGIKLVEPLGEMLTFSWEEYATKMANAMTAEKLISVIKEIVTLENIDVNCTANVVVARDTRPSGLKLAEAFIEGVKVLHGNVKDYGVLTTPQLHYLVRCLNTSDSASFYGSPTEDGYYQKLSDAFKTIVDGQKKISPLYVDAANGVGAKALSSLSKVIGSQHFDCYIANAEISKPEKLNFQCGADYVKLEQTGPFGLEIKPNMRCCSLDGDADRIVYFYVNNDNVFKLLDGDKIATLSAWFLIDLIKKSGVKINGRELKIGLVQTAYANGSATQYATKSLKVPVVFTETGVKHLHHEALKYDIGIYFEANGHGTVLFSESAIKAFRDEKGEYHFSSIKSKNESQIKALRILVSFSQLINQAVGDALSDMLLVEAILTLTQTTLESWDSAYKNLPNLQVKVKVTDKNIFKAIKADTELAEPAEVQKFINNQVKNYSRARCFVRPSGTEDVVRIYSEALTQPENEKLSKAVCEYIRLQFGNIESESFEKSDGAVSITRNVSNVQHRGLKIKYNGKLLNSCNQIGVWVQINNRSTGTKTKSIINGETEIFSPSDDPLDEYLVGKDKNEKWDVQLAFVDINGNWDSKLGQNYHFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4M0</accession>
    <name>A0AAD5U4M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Anthranilate phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TRP4</name>
        <name evidence="5" type="ORF">HK099_008590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000096">
        <property type="protein sequence ID" value="KAJ3224346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4M0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.970.10">
        <property type="entry name" value="Transferase, Pyrimidine Nucleoside Phosphorylase, Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285:SF2">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 3 N-terminal" evidence="4">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 3" evidence="3">
        <location>
            <begin position="96"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="356" mass="37919" checksum="6186CF290D67C6F2" modified="2024-05-29" version="1">MTVELMKTGLKKLTTDSKNFTAEDAACLTTIIMNGNATPAQVASFLTALKLTGKETEPNFVAAAKSVNEILVAASMRNASVHIPYVGPSGMIDGQMVVDIVGTGGDGQDTFNVSTASSLVAAGAGIKVAKHGNRASSSQCGSADVLEYLGCNLNSVEPPHVLQQLKYNNFCFLFAQKFHPSMKNVALPRKELGPLSNPAVPKRMVVGVHSKEIGLMMAESLKLSGIERGLVVCGDEGLDEISPEGVTNTWSFDSSSNDIKFKKIYPEADFGLKSHPLSTCKGGNVKFNAEIMLKLLRNELPPGSPLLNFVLINSAALIFTAGKAETFKEGVELARRSLADLKAFEAFDGFLKATNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4M3</accession>
    <name>A0AAD5U4M3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Actin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ACTIN2</name>
        <name evidence="7" type="ORF">HK099_003684</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000243">
        <property type="protein sequence ID" value="KAJ3221232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4M3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000015">
        <property type="entry name" value="Actin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000502">
        <property type="entry name" value="Actin-Related Proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="369" mass="41319" checksum="21E060A69230B1EC" modified="2024-05-29" version="1" fragment="single">MNDLNSVLLNQPVVIDNGSGIIKVEIETENKKNKHVGRPKHVRIMAGAIEGDCFIGKKAQELRGLLKIRYPMEHGIVTDWDDMERIWQHIYSEELKTLSEEHPILLTTAPLNPKKNREKAAQILFETFNAPSLFMSIQAILALYASGRTTGIVLDSGDGVTHSVPVFEGFAVPHAIRRVDVAGRDVTEHLQLLLRKAGLHFHTSAEKEIVRLVKEKSCYIALNPSKEEKESSSKEVDFVLPDGNVIKLGAERFRAPEILFNPEIIGLEYPGIHQVVVDSINKADLDLRKSLFSNIVLSGGTTLCKGFGDRLLNDVKKLALRDLKVRIFAPPDRKYATWIGGSILASLSTFKKMWVSAEEYQEDPDIIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4M8</accession>
    <name>A0AAD5U4M8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FKH2</name>
        <name evidence="10" type="ORF">HK099_002012</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000163">
        <property type="protein sequence ID" value="KAJ3222702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4M8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22701">
        <property type="entry name" value="FHA_FKH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF1">
        <property type="entry name" value="FORK HEAD PROTEIN HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="9">
        <location>
            <begin position="204"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="204"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="429"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="439"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="571" mass="64584" checksum="71EB679FB92BEB5E" modified="2024-05-29" version="1">MTSQAYAKLEGTGSWIYFITKLTIKIGRNSVNEKVDLDLGIQKTISRLHATISYNFLSRKWLLLVQGRNGLKVGNVQYKVSSNPIVLENGNTIEIGGIKFTFNLPTTPPTVNNSKNPTIRNSQPSSKQSPQNDPQKGNSPNTTDMLNVTESEELKDRLSKDSKVQLTISDSTDENGKQSSTIENSKSDFKNNSLANNITNSYLKPKISFVDLIKEAILNDKGKKLTLIGIFNYIRLQYPYYKYLEEVNKNILLVGDQDWKNSIKIILNKNSSFKKVNKNLERIYWAVNTSDNFIYDTLKRNLLEEEDVEHINDLKKIKYSASETSTATQYSEQVNAITKSSSALGSSKGKQIPTSSIESMFSKNDIHQKFFDPNFWSKEVSSPFISKELFQKELIDLTLKNNFPTNGNVLKKQPSSFVEKDIVTETLSENDSKNKADDFNNSNIVRKNNRGFSEKSQNIESAESSSVKKTDAVISSSSKMLPMEEVKVKASPTTNFSFNNRGRYNASNRSGSVVDLNKIIFHKNSNLIHLNEVKLKVPTPESIMKGFPVYFYEFKKLSNFNLISKDSVFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4T1</accession>
    <name>A0AAD5U4T1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000094">
        <property type="protein sequence ID" value="KAJ3224392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4T1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="77" mass="8964" checksum="56F6531AE9090838" modified="2024-05-29" version="1">MQIGNLENLNSGVDYIVNKDENIIDRGVTASEDKNSEIKVHYYDNLLNEPKVPVEMIDAKLNNIKKKHRFQLRSKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4U4</accession>
    <name>A0AAD5U4U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008459</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TBCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4U4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01789">
        <property type="entry name" value="Ubl_TBCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.190:FF:000013">
        <property type="entry name" value="Tubulin-folding cofactor B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045172">
        <property type="entry name" value="TBCB_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF85">
        <property type="entry name" value="TUBULIN-FOLDING COFACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14560">
        <property type="entry name" value="Ubiquitin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="5">
        <location>
            <begin position="177"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="241" mass="27536" checksum="C7BDFB5F513F7FE3" modified="2024-05-29" version="1">MVNEVSLPGPSLLTLFITSESSSSERRFEKSITIGTLKEKLEFITGVPCATCKLILYTKENNQVAVLDDDTKMLGFYPVYDFMRIEAVDTNPHRIHSQYTDLSKVKKFEISQEEYEKKTDSVRAFKERNKIGRFSEKEAEPTNIETFEEEAKALKIGARCEVDTDGYKKRGEVRFIGSTTFKPGFWVGVKYDEPVGIHNGTVDGVKYFECQNKFGAMVRPNKVKVGDFPEENLFEDDDDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Z1</accession>
    <name>A0AAD5U4Z1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_008198</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14014">
        <property type="entry name" value="STKc_PknB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="9">
        <location>
            <begin position="1787"/>
            <end position="2111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1747"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2142"/>
            <end position="2230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2176"/>
            <end position="2207"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="1862"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="1862"/>
            <end position="1866"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1866"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1903"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1904"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1904"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1904"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="2015"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="2015"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="2066"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2256" mass="255414" checksum="0B5B2815D7358FF9" modified="2024-05-29" version="1">MAGLLLIPEYSDYELLHYNPNNSLIVQRARCKENPQQSVICKGLTNFDQYENEKLKMEFEILNSIHEKLEQYERQKNDLNSLSLDDLCYSVKDVRRGSQELRRFQSLKCGTNIQNPSWRIVKPKGLKMYNDNCYLILEDFGGQPLRQYLSSNIANGCNIGNNATAPHSSINIEEFLLIAHQLSEALDIIHSMEIIHKDINPDNIVIKKIINEYGKLKTYIQLIDFNLAKVNRHDNEQGEFFQGTLAYMSPEQTGRTEQTLDHRTDFYSMGIMLWEFLIGKTPYDYEADDVAEYIHSHLALELDAPEEVDSTIPHIISELVMKLASKLPEDRYQSASGLRFDIEAMLAHIKNYKEACGLNIDEYLDNSRMLECFTDLDMVLGLKDLSDKLYIPDLIFGRELEYKKLVEAYQRVSMGIQSREVCFVSGPFGLGKSSLVNKLHRHINDNSGCFVSGKYDAYTKGGTYSGILEAMRNAINSFLALSHEEFNEWSEILKNSVSKENLQILAELLPDLTFLTGIQQGNQAALSESDKISVNKREADEDSIEFIKEVLVDNTVSHLLILLTCRTKNSIENNILSDIVNSVHNNPNTPVITQIPLSPITASHVLEMLEKVFFPLASNHGDLNALASLIQAKTLGNPYHIKEFLKHADRMGFVYLNRHQEGWSWDLQAIEQMAMADNVVDFMLLRMKDLPEETLHLLKIAACYGNKFDFRSLSTISEINTHLVSNHLWIAMKEGFLISSSDSKFSKVPIRLSRSSSNLSPPLISSCPKLFSKPSEKHSVIVERILSKSGNQSHSPLDLEFCHERIQKAAYAMLKETENKTIHLKIAQLIQKKFYDSECIDENVFELVEHFNEAEDLLYEPGILVYGAKLNYIGAVRAKKTYANLKAKQLFQQGLKFFKKLDTLNFDFENNCIENDFEGNNFDLNDLKIKLIKGLILTHEIEDEMDEAEVLCKELLAISKSTVNRISATQILIGIHSSQYRYKDMLELALKELTNSGVDISTNKPSLHHALVDEFQKFDNFISNNNLLELQCKPVLDEAQQLIQNLLQSAFDAAEKIGCNELGDLLVLMGCNSILKNGFGKKSALFFASVTRIYFEQPTSQFPDMQKLKLITEFTSKLIQNSVTEDKIKALFNQFNYGQAYVLTQRRQIEGLLRSTFMLSKEIANQKFAMHAASQLLTFQLHQGQPTALLRETSKLMQTTAYKNLSPASNTWSMIVMCLDALCFNSEIATYTSLPVTLKNTLDAINFMYLVIYEHSEAAAMCKSLAANIVAHKPYVRNITISVLSVRVLCMEYTNCEKGNLKSVKSQIDKRLDEDSYKKEILQLINEKISWLKNFTSDLGNEQHCKYLIAIAERDRITGNIWSAVHNYESAIEHAHKNGFIMWEAYATELMAKCFVEQQNRRLSKVCMSTAYSLWKNWGSEGKMKQLISLYSEYLPEQLSSSLRQSGYKGPTGSNFRASINSSASTTANNLDVTTMLKVTQSITNESNLEELLAKVIKYVMVNACARKAVLALNEGGKLFVKAHAVTMEGDEQTKVLKDSIPIEKIGLHGEGSLPLSIILFVYRSREFIVLQDAVSDQMYGKDTYIRQYVPRSILCIPIVHQNAVSGVLYLENDTQLGVFNADRVELIKSLMASTSIAIENAKLTKRNNELIIALKHTQKDVNSLNAGPKYNIDAPIKKTIDVLSAMKSSLSIDDPTIQQIDYVMKMLTSSDLFSSNIDDINDEQGRGIDQDTKTWIENSLLQKYTRKPGVDREESEDSMMFGSDQNEESTPRSPSKLTVFRGASELSPLNYPEILALLELSSTQEFDVFKLQEATHGRPLYFLGCHLLEKYGLIKHFNLSESTVRKFFETIEANYHNIPFHNSSHGSDVLQTVNLLLLSDAKMASYFSKLEILAALIASAVHDVDHPGLNNNFLVQSNQKIAVLYNDVSVLEFHHASKAFQIASNPESNIFTGMAKDQFRDVRKLIISMVVATDMAQHFQYINKLKGKIVTSSLRLEDAVDRTLVLEMAIKCADLNNPSKPTEQCTKWVYNLMKEFFVQGDLERKMGIPVTMFMDRNDMNIPKCQIGFIDILVTPLFDSWSQCIKTDFSRYCMENLVKNRAYWESLLCNPDAVPKFPPEENEYFDMDYLNERFFGSQAFGSITPPQPITSQQQSNKDKILRSPTKSPVARGSMKRTVSNGAQKSPSTASPQYNLNSSNIQPTSTKNRPMIKIASVPPLPGANRLQTLPDLPNKVVQYALSTNSNLNPSQKSNSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U536</accession>
    <name>A0AAD5U536_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HTS1</name>
        <name evidence="11" type="ORF">HK099_003368</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000221">
        <property type="protein sequence ID" value="KAJ3221581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U536"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000012">
        <property type="entry name" value="Histidine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000021">
        <property type="entry name" value="Probable histidine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476:SF7">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="33"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="102"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="304"/>
            <end position="305"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001549-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="473" mass="53074" checksum="9543C6218CE89D11" modified="2024-05-29" version="1">MSTTTANKENISEKKKDDKKVDVKKFTLKTPKGTRDFNDKEMAVREKLISTVTKIFKKHGAVTIDTPVFELKEILSGKYGEDSKLIYDLQDQGGELSSLRYDLTVPFARFIAMNGSKYQNIKRYHIAKVYRRDQPAVAKGRMREFYQCDFDIAGVYEPMIPDSEALVVMWEILKEVDIGDFIIKLNNRKILDGMFQVCGVPEEKIRPISSAVDKLDKATWEEVKKEMVTEKGLEEEVADKIGEYVKLKGSKELVDILEKDLNFSSNLKVKEGLSEMRTLLNYLEVMGVLPSVSFDLSLARGLDYYTGVIYEAILVKSSVDTSGVGSVASGGRYDDLVGMFSGGAKIPCVGMSIGLERIFAILLKKTKPESIRATETQVYVCGIADGTLLDRMKICSELWDAGISATFQYKDKVKLGQQFKICERDQIPLAVIIGSGEIEQGVVNLKLQYEGSKQVEVDRKDMVTEIKKLLNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U595</accession>
    <name>A0AAD5U595_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ZZ-type zinc finger-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ZZZ3</name>
        <name evidence="4" type="ORF">HK099_007739</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U595"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037830">
        <property type="entry name" value="ZZZ3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22705">
        <property type="entry name" value="ZINC FINGER, ZZ DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22705:SF0">
        <property type="entry name" value="ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="264"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="478" mass="54228" checksum="75B53FCE177AD1F2" modified="2024-05-29" version="1">MDLSSKSMSDTSNNKDIISDAASEDTKVSENVTNELDNENYKLIMSAITVLQNQLNIARSNLETLEKMKQEALNNPYEFVQQIKFKRYKPTPKLQKIISIPSPEGFFNSESKNFQKLPLQSKNILRNDSYMSYATKIQKKLNNAQSLVQQQQQIPPPLQSSNLTYLTNYVKNKIGSSTINQLTADHHKYSTPSSPTSSSSPANSPVNSPLNINSVGNRQKSLLRLEEFNYSLNDNIEDEDSVSNIELEPKKKKMKIASSASSTFGALWSREEQDLLDKLLEKYPDDGTNKRDRLDKIANEFGTRTKKQIYSRLQKIKNTGTSEVKKKVISGAQYMYAPTVKMTNEDLDELMADSDISSVHSGSDAEIDEKLLGTEDYKELKKLQNLVKANKGKKYGLKPVHHGFKCDLCETEPILGVKNYERFELKFFRKGIHVKTVLKGLRLTCAVNVLINSTPMHFKAAPFNKFYEKADEYSYLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5J0</accession>
    <name>A0AAD5U5J0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NPC2_3</name>
        <name evidence="10" type="ORF">HK099_007490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000073">
        <property type="protein sequence ID" value="KAJ3225017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5J0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042000011" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="8">
        <location>
            <begin position="18"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="9">
        <location>
            <begin position="23"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3225017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="15784" checksum="BF60936DB3448BC9" modified="2024-05-29" version="1">MKISLLLLVVLVTFVVAQLPDGFKSCGTAQDNFTLQKLIVNPLNPVIGKEVQITAHGNVNFEDIVEGATVKVVAKVGNIITVLDKVFNLCEQAATANITCPIKVGPNEFGVKLLVPSNTPSIKVTVKATITNANGNAVGCFTGPLQIVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5X9</accession>
    <name>A0AAD5U5X9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5X9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088:SF27">
        <property type="entry name" value="DEAMINATED GLUTATHIONE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088">
        <property type="entry name" value="NITRILASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="383"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="659" mass="75111" checksum="67E286696A55802E" modified="2024-05-29" version="1">MIRINPLYNSFHSLPCHDEVYILKKRLEISDLLARFEHFKLIPDGFGKFYYNNHMFTLASEISAKLNKKSLPETLREKVFKPAKMNETIMWEEVEDKSNLNMFTAAVLDIDPLSDSRIPDKFSALPISVNDDLFTVGSGCGGVLSHSVDMARYMQFLMSRAAGSLIKEKEFSEFVKPHINSQNPEKVNHYGLGIEVTEYEGNLSWDHDGQVFGYLAKMQILPEKELGVFVATNGYAHGPLMSITNVILDTLLEIPFEKKKNHPEYYAEEYKEEWKGKLRKFDEIVENKTMHQMDLSKYVGEFYNAGYGTFTLAFDAISKKIEGKLLDTTFFDFNHFDKEEFKCKSIYPNVNWAATTYYDKKSCWFDVENEEIVSVRLELEPGLKEGIIFLRFTGTSLKQKNKALCLDLIKKAKSSNAAMIFFPEVSDFFAENAQQASEYSELLSGDFVTSIKDGAKLNKIFVSIGIHEKFENKFYNSHIVINDKGDLISKYRKLHLFDVDIENGPKLLESDSTIKGNSIASPVETAVGRVGLGICYDLRFPEFSTLQRKKGAELLTFPSAFTVKTGISHWFPLLQARAIENQCYVVASAQIGKHNANRESFGHACVIDPWGSIIAQCPNVTYPCIALAEINLGYLKKIRLEMPVFEHRRMDIYSLTENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U637</accession>
    <name>A0AAD5U637_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000051">
        <property type="protein sequence ID" value="KAJ3225832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U637"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="180"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="293" mass="35122" checksum="FB27C7990BD11636" modified="2024-05-29" version="1">MDDHSSSVSDIVPDTPFHLSELNRDIADTDSSFEKNSIQKHSEIYSEQFSPQSSKSSDLQKYNSDFVDEEIDIALLIKKFKEIDSKVNDDAFKNWKRNKFNSSSNSISKEAEKKNCVEKTRATNSAVVKEKPKRNFNEIVSNLKLHQEELKFFAVDELESKVKNLIKNEENFKLWKDKKNKEEQRARELKLLELENLKKEQHLQELKRLEKSYREQEAIKKWKMEKLKIEKSKELKEQEEKKKKLELLRIREEKGKEVFKRWLKEKKSKSKIPEEKFYYKHEKEFQVDIENIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U640</accession>
    <name>A0AAD5U640_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000232">
        <property type="protein sequence ID" value="KAJ3221399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U640"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="80"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="281" mass="31724" checksum="63D8A20253556C4F" modified="2024-05-29" version="1">MIQKTLLGTLDELIADIDNFLIHNENPLPALPNSHLLQNNSKHLSIAPSITSSKSSNAFTSTMNNSSTLDGTLRYVSSLSDSFGGWVYKRSQKKKYIILANHTLYIYNSDAFPSATYEDYLPITSVATCQMSKKKLNCLEFKTQFTTKLNKLDDGVAEEELNYLVNKKLEFQFSKTEEMQVWLSCFNEAINEVKNEKNMNPDSIPYSPTSITDSSTLRYNNSSPPTSPRSTLLSPNLSFDDRSSYSDSIIPLSRSKSWGGYRTSRKLSATQTERDILHLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U659</accession>
    <name>A0AAD5U659_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histone-lysine N-methyltransferase, H3 lysine-4 specific</fullName>
            <ecNumber evidence="2">2.1.1.354</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">SET domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="primary">SET1</name>
        <name evidence="24" type="ORF">HK099_005966</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60260"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.354"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60272"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60268"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="Rhea" id="RHEA-COMP:15543"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.354" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19169">
        <property type="entry name" value="SET_SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024657">
        <property type="entry name" value="COMPASS_Set1_N-SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044570">
        <property type="entry name" value="Set1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037841">
        <property type="entry name" value="SET_SETD1A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11764">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 24" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 19" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="146"/>
            <end position="176"/>
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    <feature type="domain" description="SET" evidence="22">
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            <begin position="1208"/>
            <end position="1325"/>
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            <begin position="1331"/>
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            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
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    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="PROSITE" id="PS50199"/>
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    <sequence length="1347" mass="153814" checksum="B332CBD97BED0BE6" modified="2024-05-29" version="1">MGDDIYFPVSETKKITAVNDLLKHDAFSKGIPPPSQVLVKNLSFGFNHEKFLQYFNRFGKVSLFETSKSFEFNFEIAKLTYDNRSDKISSGNSARAAVFKSQTFKKIEPSFAIEFDPIGQKFNSFKEKNNLSSKVSLSNLSTKILKESKEWICPSCKYHNLPNSSACDICQTINDTPSKMKISSNLQNHPYTEKKIYSTNTPLRTQSDPTAYLKIKSDPRKYPTSNSQFINIPKATSKELKNRTGSRRSDSSDSNLSGSSKSYSSSSESKSSSLEKRGRSVSVSDSRSATSRSLYKTRQGSEVSSSSQNRYLGFSGRDPFIPYHLREDPYYDKNVTRDPYAPKYRRSEESASTYSRDYDYSLRSNRDSLYNSSRGDDFIPENSDFIPRYPGSGEKRVSQLPKFTDDLTVNKYPGPGVNKYPGSGETKIRGALDSRKSLYDTRPSSYDEFDKYPKRDLYEHYPSRRYSNNRSSRSRSRSASIGYSRRSSKSPKRYSNVRSPNSYLGGAEKTPEPFKKNVVNSKTNKQSFKTEDNSDIKRINGNNENSPEPFRRKTGNNETTPEPFIRRTKTNTASPEPFVRSNNTNKSSPEPFLRKNVSSSSVAKLSESKPLLGKLPTTGQVAKYPLCRFTPNCTKSNCQYFHPPSKDVSKNLTKSEIEKSEILTEKVLKLLRTELSVIFMRDLKSRFVLPMVTDLLTKSIEVHNKQVQQENLRIENTKLLESVHTNANSGNINEGENDSAQEEDSILQRMLPRGFLSKKLPSFKKRIQISSSKDESTNNSVRKKLQKKIYTSSSSSYSSSEEDFTPPPRRKKIVSKTHQRVGSKTVPESEEESDEAKQDLALSVLSDKSMKGSVPESPMDNSFHKDSLENTVSLDTAKGDLNEVLTPPVDIMEDDFEDLDDFDDFDDFFLEKRKKKSKLAKKSRKIKKSAEEVVKISSQPPTKALKGKMKKKGWIRDVDVEYNDKSESVTPHLSPGAIDAKDFILSSSEEESMDEFVKQLSPDFNWKTKYDEIYMYNVWEYLKCGIIEEKWEDEIYFKVMDKKNEREEYSGEEVIFDEIYFPVKNNVKEFEDLKGKEFYSKTHGTLIFSLDSHKLNLFPDYSEPHKTGSARTEGYYKIHSKSNSAGKPSQVDDIREDNLTEKLPTDNFGRNATSKISSRTTRVHQRRLAFGLETQKKENVNMFNSGNANTTENHIDSLKFNQLKARKKRLKFARSKIHDWGLFALEKIDANDMVIEYIGEIIRQKIADHREKIYEKMGIGSSYLFRMDEDSIIDATKIGNLARFINHCCDPNCNAKIISVEGHKKIVIYAKNDIEEGEEITYDYKFPLEDDKIPCHCGGPNCRGSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U662</accession>
    <name>A0AAD5U662_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Myoadenylate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AMD1_1</name>
        <name evidence="14" type="ORF">HK099_006276</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="4"/>
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        <property type="protein sequence ID" value="KAJ3225776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.800.20:FF:000001">
        <property type="entry name" value="AMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000035">
        <property type="entry name" value="Probable amp deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
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    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="956"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1048"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1071"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1111"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
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            <begin position="1171"/>
            <end position="1191"/>
        </location>
    </feature>
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        <location>
            <begin position="1250"/>
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        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="13">
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            <begin position="885"/>
            <end position="1262"/>
        </location>
    </feature>
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            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
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        <location>
            <begin position="195"/>
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        </location>
    </feature>
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        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
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        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00004955"/>
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            <dbReference type="ARBA" id="ARBA00006676"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072037"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00078830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1371" mass="159088" checksum="AC03ACC775A3A9A3" modified="2024-05-29" version="1">MSNLKKEIKLNQLKPDNSRGDLDIVKSRSTSSTSPSNPASLSQYGSQQFTDPMELVNTVTTQGSPFFDYNNEKSMQQEDTKYWAHRIGKLSGYGQAYLPEENDSLSRISRASSFSEASLSTRSMSLAERMADAHGIPVTHESVAMFAKDTEAHDNKDNILSAELQHIFSTWRKCLQLRHKYIDCSLQNFGANPKDQDDWEIYPKPPPPSYKPSGKLDSDSIAEVKSDMESFNMEDCKIPDSHSYSFRMCSDGVYRVFKLPCTLENRENNNPLYNVPTLKEYFTDLEFVLNIISDGPTKSFAYRRLRYLESKFHMYILLNEYQEMADSKRVPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKMKKSPNDLVIFRDEKYLTLNQVFESLNLTAYDLSIDTLDMHAHKDSFHRFDKFNLKYNPIGESRLREIFLKTDNFIKGRYLAELTKEVISDLESSKYQLPEYRISIYGRSKKEWDLLADWIVDNKLFSTNVRWLIQIPRLYSVYKASNLVKNFEEVISNIFEPLFKVTLDPKSNPKLHVFLQRVIGFDSVDDESIAEKRTYKKYPFPKDWNISLNPPYSYYIYYMYANMTQLNQWRKERGFNTFVLRPHAGEAGDTDHLTSAFLTSQSISHGILLRKVPALQYLYYLDQIGIAMSPLSNNALFLAYDRNPILNFFHRGLNVSLSTDDPLQFHFTKEPLIEEYSVAAQIFKLSGTDLCELARHSVLQSGYEMKLKKRWLGDKCHMAGPVGNDIEKTNVPNIRLAYRYQTLMEERFMVIGLNGDFSGFDDGNAIRESNERGEKDALNSSVLMSSKINPADEKKFVAPPEPLLTGSSPGLKASVNQKEYSAALSPTLGTKFLSDDDPNLELLELSPPGFAALQVLHTHYPDFKYWILYNGSPSPQNYYQTLLGELLAGTSPFAVTIFFVLSGRVMANGILKNPKVEVLFSAIFRRFFRLLIPLLGSYSIYYIFLSSGIAKPDREALELAKGTRFGAMFWIYGYYDWAINQMHWYGPLFWTLNLLNNGFGYNVFPMGIWYNAWTIPHEIYQSLVVFFTAFLVVPLNTRQKAFVYFIMTFFFFWINSWGCAFMIGLIIAEFSKNSFFQRLNKNKFWFLFHIIFAIFPILYWCRFLKKDPANNFIDNFEIKYRNNIWGTKGIGNDSQFNASSMWAYPSAGTLAFSFSFMMLLELNSIIQWIFSLRIMKFLGKISFGMYLSHPMFLVSLYPKLVKYILQHPDTFKSYSPFQQHLLVYLVVLMFLAVYSLLFYYVFDKGSIYIGRSMHSLFKNGIKNFKIKASFKPLSFLNKMIVSISNFPHYILNLVFALYKNIIQFPSEVKFKLLYAKDCFFPLFKNESTYSEIQDIEETTKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6A5</accession>
    <name>A0AAD5U6A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000050">
        <property type="protein sequence ID" value="KAJ3225857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6A5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="883" mass="103785" checksum="171E87BE4204CC46" modified="2024-05-29" version="1">MASVSDVINHSVNSVNYVNSVNSLNFTQTTTNSEVRVTSNQRSDEVLIKDKYSSQIYLLSWIEILVATWFHAKEVNIGYLTILEDEVTEGSRLLDNYNQSFQGTSTDIHCEKLESDKKMELNIDIDMIEHSLILPYTKEFIYSGLSLDNAFLYLEEENIFCLRKSFKLFWDFDLNAIEFDLNCLSDYYTDWDVKFQTSCSIAEKLKKAGVLIFYFVYLQFHVVQYLFTNDSYYLASLMEQMNIAHESISKLKNLHNGLKENNLNPKILPTILTGQYLFEQKSDSDSTIINYWSHLELQLYEAESLFFKGLFNVYNEKVVKGGTNLMTSFNILLDIKLKIVNDMNSNLNLFNQNSLTLKFDVYNIKHRVFENFYFLMGCYFLLSIWNKSLVLSTILKSIVYIPHEPFQHWNPKLAGVKFLTIVGNGDGLRAPVSVFALTVWFSTKSSKDLTSELFHVADPIFSASFCADAYSEISNELKVDLYSSCYEKVIILDLDLISSYYNELIFSIVSITNQYYLSKRNSPVFKYCLYKVYRSIGELELSDKILFQLLHEYYDFDFESFYTTILFEYGKILLIKAQFAFSFEIFKFIWESTFFNFTEKDSAHSVQAETIALVGLILVGLKRFLNLDELRNLEVNLKRFCYVNNILSKNIFFKFSLILFMQEKKKKEVDNTLIYHILMNLNEFKSFKLKNFNDLNNCNVFDTHIELLKTCLNETIDYDIEIKEKKQLDLIIQNNLILTLITHLELENLLNFLQFNNNLSSKNSSLKKKKLEVFIKLKDTYNLLLRNIENQFFNLAKKKIFFLEYLELNHYIYVKILLNFILLKKIEKDSEAEEKLKLKLKNYLFHKAITNENGNQKVINFKKNENFDNFDLSCLWEEYNLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6D5</accession>
    <name>A0AAD5U6D5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000050">
        <property type="protein sequence ID" value="KAJ3225862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6D5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="605" mass="71909" checksum="675F81D9CD72CDDC" modified="2024-05-29" version="1">MKNIKLNFDMKILKQLDQHKIHISNKNSNTSLLDLANHLDQLIKEEFNISTVNFLVDYFKLGDEQFSGPLWHLNEYVITLLKNYVKDFEDEDFTNQLFFLCKEFMERQKKGYKISQYIDTTIGHQILIQLVANSFNGIFTLKNKKNKQNVLERLANFYSSQKLPEAVGHALIWILEQPRLIFAVSHSQKRVFHHPDLVEFCFEHMLTLLFPKSEKNSNAPKKKNLNSFQSNSLDFINQLLNEFNEFYILFQSLQKTETNSIFRKPQISINSFLYLLDVLKQTKSNFCNSTIENALIVDIYTTLRKCILEIQSIEINNSKEQFLKILNTFSNERDIWIRNELKAFIAGLFTLEYYKIQGNEQYEVWLMHLNAHPLETQEILDYLLQEAKKNSVTWKKNVSLVCYENKSDDYNRILRVTTVLFNTKIEYKDILNFVFPFFIAIKKEDQQKAFNFQIFLEVSCNDSDSCDTTEFCSLDDIAAEPIPCLWKSEFYLKNEEYFHHALPTLQYNFNNFKNNLVQTFNKNFNQFDKKVGINSHKYIKNANSTLHKQILPQYYIIKKDILKFYNHNAYPAFEFVRNSWIYRELFNMVEELDSHLHKFAKVIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Y3</accession>
    <name>A0AAD5U6Y3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000030">
        <property type="protein sequence ID" value="KAJ3226710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Y3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="673" mass="76256" checksum="CE3678A7C861B52D" modified="2024-05-29" version="1">MTTVMTEYNISSELKKEQQQADANEEEVFCKNPPYQSPKSVAEEEMLIEYMDDDDDELLVTDASKTTAVVSELVVYDDAEEGFAANEDVQQDEEAVLDESKSAEGLNNLEGKLSSDFFDNETTYLSEVGEPSQVNIVFGNCEEEDLEKVVDVMTNNTEAEENFCLVDAEKMNETTDFGENGDLNNLEETNIDMMQEVESEALKISESIVDVLVDNIPAFNENVKEEQSNTEIVEKNDENVSSEEFIENTSTAQNVDVLEDKEEYLEFYTEGDSKVGEDDKLIGEIEVKNSLKQENIDNFEDVNVVEQMDLVEQVDDSDDVSAQSFTNFDENKVESVDENLNSGDTSVQENDTYNPNSFEEIFDFSQFNSKYLAPVLLEFNGVKYHIFPKIENSEYNSAEESFNLPNHILSNINFTEKEEIKNLTSSESDINQLENFESIYLIDENFLDSEFYFEKLTNLFLGIKSLLQIENDLIIEFPQLQLSFHELYYTSNEVSLSELFGLFCDLEPVKSYNEPFKMLLSEAANSHIERLQFLRSLQCNSSIEDLENKSTTTHSFNDFIDQTEIFETSPDVEEVIDEAIDEAIEKSSHISSEMKSELAPEEDVSPTLNSTEDTGFSPEITKGDNEGSSIVAEISGVTEIDDTQSMSIVDSEEKLKRKADENLEGQAKFLKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7K3</accession>
    <name>A0AAD5U7K3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">WD repeat-containing protein 82</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">WDR82</name>
        <name evidence="11" type="ORF">HK099_001130</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat SWD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7K3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006384">
        <property type="entry name" value="HAD_hydro_PyrdxlP_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016965">
        <property type="entry name" value="Pase_PHOSPHO-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037867">
        <property type="entry name" value="Swd2/WDR82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01489">
        <property type="entry name" value="DKMTPPase-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861">
        <property type="entry name" value="WD40 REPEAT PROTEIN SWD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06888">
        <property type="entry name" value="Put_Phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="97"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="255"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="520" mass="59222" checksum="7461352073F30F3A" modified="2024-05-29" version="1">MSLLLSHELGEFQIGKIFNDNKKTITSLDFDDTGEFCLTTSKDESLRIYNCLDGNKKYGCNLARFTHKSTNVIHSSTKEDDQIRYLSFHDNKYIRYFKGHTKRVVNLQVSPVEDLFLSSSLDGTIRLWDLRQSSSVGLLTIPTNFSKNQTKSCVAFDPSGLVFAVGHDSRCVRLYDCRNFDAGPFLTDDISQQSNYTLSSTEIFEWHSLEFSKDSEKLLISTNGNNSIVLNGENLDFEYIVNGYNNNAGMELEASFTPDCKYILCGSQDGLINFWDINDGRHICALPGTFTEEDSDEFAFTKIGSKVLLETIQTERSKYNCFTDHVANFLQHLHREGVTKEIMSEKFKELKVHYALPKLLELAKTDNADIIILSDSNTFYIETILKSNSLESYIKCIVTNPGAFDENGCLIVNRRTTIDNPHNCKNCQLNICKGTELLTIIKDCSYEKVFYFGDGKNDYCPSTKLSAADVTFVREGYALEKMLESEELSKLVKAEVVKWKDMNDLVFYFERLNGINKERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7R5</accession>
    <name>A0AAD5U7R5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7R5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="76" mass="8786" checksum="34966B4B878F78FA" modified="2024-05-29" version="1">MIFNQQTLATTTMAKKFSKDLNKEVSTKMHHNHAVPSTYNEKQTSFEKKDMITQTQQNDNPIKVFNVPIKFAQSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7T1</accession>
    <name>A0AAD5U7T1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Suppressor of loss of ypt1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SLY41</name>
        <name evidence="7" type="ORF">HK099_000790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7T1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="3"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="98"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="302" mass="34625" checksum="A0CD8764D80E5A1D" modified="2024-05-29" version="1">MVALAPLFTVLIYRIFWQVIYSRRIYLSLVPLTVGVMLVCSSNVKFHSIGFFCSLMSTLIFATQNIFSKKLFLHARHANLEQIQTKLNKNNQNNSLNSPINTTAQNIGNKVADLKLDKLNLLFYSAFLAFILMFPIWMYTEGIQFFTDYSILPSMKVSFLFLLNGVTNFTQNMFAFTILSLVSPVTYSIASLVKRIFVITASIIWFGDSVSKLQGFGIFLTFLGLWMYDQARMDVAKSEARLNLTESTTLTLPTTNILNKNRDEEEKSRSWNKDSIPRSNSFNKNINLNEIYSRGSYLKEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7U5</accession>
    <name>A0AAD5U7U5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008282</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7U5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42871">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42871:SF1">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="8225" checksum="0CCAE03414DA0073" modified="2024-05-29" version="1">MLNHQIKVTDHRTGKSYNLPVEDGTIDSSFFSQIGLSIHDNGYTNTAVCRSAITYIDGDKGILRYRGYDIEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7V0</accession>
    <name>A0AAD5U7V0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MOB kinase activator 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MOB1B</name>
        <name evidence="3" type="ORF">HK099_008297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7V0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="133" mass="15269" checksum="DC56833E44ED8004" modified="2024-05-29" version="1">MNFLGNLRGNNRTFKPKKNLPEGSKQYQLKKYAEATLGTGNLRTAVELPEGEDINEWLAVNTVDFFNQINMLYGTITEFCTPNECPIMSAGPKYEYHWCDGVQYKKPVKVSAPEYVDFLMTWVKKKAEVDSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U874</accession>
    <name>A0AAD5U874_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <shortName evidence="14">ETF-QO</shortName>
            <ecNumber evidence="14">1.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_007312</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 14">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + oxidized [electron-transfer flavoprotein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="14"/>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U874"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000012">
        <property type="entry name" value="Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049398">
        <property type="entry name" value="ETF-QO/FixC_UQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007859">
        <property type="entry name" value="ETF-QO/FixX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617:SF107">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21162">
        <property type="entry name" value="ETFQO_UQ-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05187">
        <property type="entry name" value="Fer4_ETF_QO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 14" id="KW-0274">FAD</keyword>
    <keyword evidence="5 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <keyword evidence="12 14" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="15">
        <location>
            <begin position="574"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00052682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3228031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="614" mass="69010" checksum="A457D75FE66C1712" modified="2024-05-29" version="1">MFRNTLLNFSKRTKLNLSNYNYRKSVICRFEQLRLFSKFSHLRDVQEKLKEDRHEADVCIVGGGPSGLSAAIRFLQLAAENEQELRVIVVEKGGEIGAHILSGAVLEPRALNELIPDWKDKNAPLLQPALKDKMYFFTKKWAIPLPHPPQMSNKGNFIVSLNNFTRWLGEQAEEAGAEIYPGYAASEVLYNEDGSVKGIATNDVGINKAGAPMDTFERGMEIHAKVTLFAEGCHGSLSKQVIKKFKLREEGKFQTYGIGLKEVWELDPSKHEPGLVSHSVGWPMDYQTYGGAFSIILVLKKIINFLLVYHLQDNLCAIGYVVALDYKNPNLSPYREFQRYKHHPFIKKYLEGGKIISYGARALNEGGIQSLPKLNFPGGALIGCSAGFMNVPKIKGTHTAMKSGMLAAEAAFEAITKEDTSNLPIDLVSYQNNLKESWVWKELNEVRNVRPSFHSALGVFGGLIYSGIDTLLLKGKVPWTFQHPKPDHEMLRPAKEYKPIDYPKPDGVISFELLDNVSRTGTNHRDNQPVHLQLQRGPKEQLERNLEIFGGPEQKFCPAGVYEYVDDEENPGKKRFQINSQNCIHCKTCDIKDPSQNINWTTPEGGDGPKYVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8B8</accession>
    <name>A0AAD5U8B8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3227014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8B8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="509" mass="59839" checksum="0596AC3CF7834A09" modified="2024-05-29" version="1">MDFSEISKIKRSLRQVRSKLAVYNNEVKRESRKYSRPKTYKDKISNILSFTHAPIKQIRSFSDFLDDLIERILESDEFESFEVRKLSKLSSFTLATNITKVNKDEDYDLEQQGYEEIPPIFRSIECPFLMESLTETFMSKFKLPHQAWCFFIKLNKIKKAVTVSDYHCFYLESKMLKRESDWLNFILNESKLEQLKNKNFSHFRKLHLKDNVNFEYKFYIKVIERSVAEYSSVNKNRNKLILKLTNEFNFVEGFHEKSTSVFATDGDLLLKGNLSILNLLSLLTKVDNKTTANINFDAVCFKKSNPESFEEAIKKCIEIDWYNLLNENYFNYEKYMIEKYLGDNCNELTIEKIHDAENVDPCENDKPEGKGWTFENALNVWYKRKTDKNMVPKNFVSLSNSSDLEPSLSKPNYVDSDESSGFDESISDVKAKWRKKRDFEDISPKKTYPLKNNFNLVEKNFYKKDIYILGKKILLKEADKEVSIGSLHQCGSKIIGDILPLNYECDDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8E6</accession>
    <name>A0AAD5U8E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CCT-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CCT2</name>
        <name evidence="11" type="ORF">HK099_002891</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8E6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03336">
        <property type="entry name" value="TCP1_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000025">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012716">
        <property type="entry name" value="Chap_CCT_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02341">
        <property type="entry name" value="chap_CCT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3228386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="528" mass="57142" checksum="3465A86222758274" modified="2024-05-29" version="1">MSGISPVQIFQDNATEERAENARLSSFVGAIAVGDLVKSTLGPKGMDKILQSLSTGEIMVTNDGATILKSIALDNAAAKILVNISKVQDDEVGDGTTSVCVLAAELLREGEKLVNQKIHPQTIVEGYRLASAAAYNALEAAAIDNSKNPSAFRQDLINIAKTTLSSKVLSQDKEHFAKLAVDAVLRLKGSTNLDNIQIIKKAGGRLIDSYLDEGFILDKKIGVNQPKRIENARILVANTPMDTDKIKIFGARVRVDATGKLAELERAERNKMKEKVEKIKAHGINCFVNRQLIYNWPEQLFADSGMMSIEHADFDGIERLALVTGGEIASTFDHPELVKLGHCDLIEEIIIGEDRLIKFSGVAAGEACTIVLRGATTHLLDEAERSLHDALCVLSQTVAEPRTLLGGGCAEMIMSKAVDEVAKVTPGKQAVACESFAKALRELPTILANNAGYDSSDLVAKLRAAHYSGNNTAGLDMYNGSIADMRTLGIVESFKLKKQVLMSASEATEMILRVDDIIRCAPRERTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9M2</accession>
    <name>A0AAD5U9M2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArfGAP with FG repeats 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AGFG1</name>
        <name evidence="2" type="ORF">HK099_004879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000036">
        <property type="protein sequence ID" value="KAJ3226426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9M2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="500" mass="54842" checksum="DFDCDF66CA1F1E93" modified="2024-05-29" version="1">MKAAAKIWLATWTPENYPFPDVGDTRKIKEFMRLKYNDMKWFRATTHPPIESPVTKSTGHPKFETISISPSKENGGSLINFLGDNGEKKVVNNIQNNSSKSVAVDLLALDDLFSPTKNSPINAVSPNNNKTFSNNNLNFSNNHFEGNKSKHQVSFTNNAAPLQSFSKPSYSNLEGLFVDTPTTVSTTESKPFSSFPGFTSPTSSVAPFNISLHQKDSTERTNKNNFGNNFGNFSNLPSSSQSNSNLANITDLFSLDIVPSHNPSLKPAEFIGTQQSSILTSPQTIANHSNFATNINSSMSKQQDFFGAQPQAVVSAEKNFALSKEVNKFGSPQSSNNNITSAPHFAVDYSAFNEIKFEEEKKPINSTGGFPEKPKAPSLRDLSNNSSNSNSPQTEKKSLTDSNNNHSRFNNNNAYSITSPDMKNMHFTATNFANFPEEKVGFGIELPNKEVDFGDFNSSFSSGLKIQSPSKNLNADISEFGAFSAFHSTNGTDFDSNPWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAL3</accession>
    <name>A0AAD5UAL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinase</fullName>
            <ecNumber evidence="4">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004503</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000824">
        <property type="term" value="F:inositol-1,4,5,6-tetrakisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008440">
        <property type="term" value="F:inositol-1,4,5-trisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF108">
        <property type="entry name" value="KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="268" mass="30635" checksum="5CE473EF258C14FC" modified="2024-05-29" version="1">MEDKLDANNWKLLDNQVGGHKDSIFVLESGLIAKPCLKTEVNFYTTLYNQYKEYQLIKHIPKYYGTTVITQDNVEKECVVLENLLKNYSHPCIIDIKIGTRLYGEAASEEKKQRMEYQAQSTTSRETGMRICGLKVVDPQSNTSFKAGKELGRSLSASTISEGFKPFFINQDKVLINKSILNQFKSKISNLIEVLKVEEYRLYSSSVLLIYDGNFAFTEVKERTEFLTDVKLIDFAHSHFCRGEGPDEGAVFGLKNLLDIIESYIRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAT6</accession>
    <name>A0AAD5UAT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000030">
        <property type="protein sequence ID" value="KAJ3226714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAT6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="249" mass="28206" checksum="A67C0B2EB115FFF4" modified="2024-05-29" version="1">MNNDAATNVIWTAVNQGWEVVKLLEFVIIPYGYFLLRPNRIAKLLFYSTIIAFIHNLLAFTAIYIEVLHVEINTFPIWFTQAMSAGIIRCIELYVNYILVNIIINSKAKKVQTMLQLVTVVAMIGVLAGRLYDSLGVEIFSFGKVRVGMAIVSLFGLLQEFWIFDNLDNSRTLLLFMDLVFTRLVANTEKAVESKTEKNKKNSIQHCPTNTSGDSYEVPELCTSEVTNSTPVFNPRVIRNTEVRKAVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBR2</accession>
    <name>A0AAD5UBR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004272</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBR2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="544"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="645"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="220"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="273"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="323"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1019"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="63"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="220"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1020"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1034"/>
            <end position="1045"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAJ3228280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1045" mass="118645" checksum="AAB90568A405B69D" modified="2024-05-29" version="1">MNTKRTSWHQSSQPSSNINNGWNSSLTPPQSPNTNQDWNAFKTELINNNPIIRNYWGSSNLEPASSHLNQTPPRSQQVDQSFNTNSWKQQSSFRGSVTPDRKSMATNSNNSWLNKPTSPNVQLSDLKMYPSEQFQINESWRQMPTCPPPVQCPNESQLSRGRHMNVIPNWTSSSSAVAAEQSNWLKQGEPSSCTSNKWTDKNYCPTETREDSWKKFDGETLNSENSTGWETQCGWTSASPTSTVTESPDWRNNLHKRRSSVDVKCRDRLFSASINAKGTRSEPSSPQQPQTSNGWNNFNLSSEISNSRQGINCELQWKPASNLNSSWNTPPVNNSVGLQSNRKLGQTRHSRSESWHGPNYTNENITNWDNSFTNSNPSWEVSPPTSVYAHNTGLPTAKVAAGWGNPIVHTNLNKRMSLQQLKSNCWNSNSSFSNENPRERVGSTIPELECEEEYDNDNFCVNSSFTRQRQNTLPESNLRRSNSSASFFDSSKKTLASGRRERFPSNQSEEIDLTFGKETSPLFKNRRKSLNYGTIENNSVVSNPRLYIYGLPNWVRVRELTDVFCDFGSVLNVGILSSEVPPFAFVEYEDSNSTLEAVFKLQHRCFFNMNQPLEIHHEQKIVPCVGSSVNGNSNGEAVDANAESTTIHVGNIPQNIQRCEVEKLFSKYGTLKRVQIVNRQKENRAFAFIGYKDHESAERAITALRNSKSLHFNMSEPLKMEYSKIEKRKLSEKSSNSSLKDAAFKEEVKLAQCKKERPFQANINNSVYAKVPKDVEDEKFLEKFKECGSVKYYFFVDRNPSSASPSNLKDLNASRLTSDAKRFAIIIYSKDADALAAVESNRFNCSFLNLKNLRLFNLNIETENMEMETLKIRNMILENLKNEENFFLKITNLNRDFKSCELEFKSAESCFNILMLILEYPENFDFKVDYGNDIQCSEIQNLSKKGKMNESSNQENDNVDAMENVRTTEVKQKNGQNENGIIAQTINDSKLDLNSSKEGLDIATEKLSLNELNLDNIPSEDLKKGKEFSKDNEYNSSSVELISVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBV0</accession>
    <name>A0AAD5UBV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NF-kappa-B-activating protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008316</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NKAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBV0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
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        <property type="entry name" value="NKAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009269">
        <property type="entry name" value="NKAP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087">
        <property type="entry name" value="NF-KAPPA B ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087:SF0">
        <property type="entry name" value="NFKB ACTIVATING PROTEIN LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06047">
        <property type="entry name" value="Nkap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="236"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="1"/>
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            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009313"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF06047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="345" mass="39782" checksum="6A2C2528318BD932" modified="2024-05-29" version="1">MVELDYNSHKNSREERNRSPLPPNDKLNGRRPYREDEKISRRRNDSYHDYENKNRESRRDYASGEMPNDAYFSERQKERESSRKSIWERSPSRSPSFDIDEPVSKSSKRKNEAKHKSRKKSRKSKSNKKKSKKSKRYSSEEESSSSSSVSSDEQEIRKKVSKNTISNREESSEEEYQEMKPEFVKPLPLKTKPKVDLDESDLITVNDFKKGGTSVVEEEDDFGPAPPLEFVVKSTGYGGDMLDGEGSAMAAYLQSGKRIPRRGEIGLTSDDITKYEEVGFVMSGSRHQMMNSVRVRKENQVISAEEKKSLLVFSQQERMRKEAEIIGGFKELVSNTFARLEKGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRH3</accession>
    <name>A0AAD5XRH3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001947">
        <property type="protein sequence ID" value="KAJ3200221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRH3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="539" mass="54210" checksum="2E5DC3D46349267B" modified="2024-05-29" version="1" fragment="single">TVASTTAKVVSTHDTSSTNAVVSSHSAESTEKETVALTSTKTVSTQDSDSTNSIVSTHTAESTAKETIVASTTAKTVSTHDVSSTNTVVSTQTAENTGKETVASTSTKTVSTQDSNSTNSIVSTHEAESTGKGTTVASTTAKAVSTQDVSSTNTVVSSHAAESTAKETVVASTTAKVVSTQDTSSTNSVVSSHAAESTEKETVASTSTKTVSTQDSNSINSIVSTHEAESTGKGTTVASTTVKAVSTHDNNSTNTVVSTHVAESTGKETVASTSTKTVSTQESNATNSIVSTHEAESTGKGTTVASTTAKAVSTQDVSSTNAVVSSHAAESNAKETVVASTTAKTVSTHDVSSTNTVVSADTAESTEKETVASTTAKTVSTQDSNSTNNIVSTHEAESTGKGTTVALTTAKTVSTHDVSSTNTVVSTHTAESTEKETVASTTAKAVSTHDVSSTNSIVSTHTAESTAKETIVASTTAKVVSTHDTSSTNTVVSSHVAESTGKETIVASTTTKAVSTKDSNSTSTSVSTHTAESTGKETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS31</accession>
    <name>A0AAD5XS31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001722">
        <property type="protein sequence ID" value="KAJ3201467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS31"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="38472" checksum="D1E739E6404C940E" modified="2024-05-29" version="1" fragment="single">EASEYNLTEAESEEDSNSLLKEGETGLGESSTSSGSSSSSVSSSSEESLTESEDEEEKEVNLDFFENFNKHFGLTRLEKTNLKENFEKFQQKVNLYQDLNTLMVAEVSKASDDCLKNLLSKKEISDKEKKKNSTGRRVDDVADCWPCPLSNGVVPGPPRPLMYTKDIDDDDDIEKQAFTFVRECNPLLEEDADSEHDEEYSEPLKRELDFVIRKINFSENLKKKKDSNEIDVFENIPEAKLNLIRNKTISFVKDLFDISFKKNKKLKSYEKINFDSILEDCNEIEDFPESVILNSEKRIKRLYPVLTKDITELNKIWEKPRKRGQRKRRRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTR1</accession>
    <name>A0AAD5XTR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000697">
        <property type="protein sequence ID" value="KAJ3213570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTR1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="298" mass="34591" checksum="E3644F1EB17C1222" modified="2024-05-29" version="1">MRLKMLSGYSILRNDIKTGDNDLIFPGHQSNAMILAEFESVIYTCSYDDTTLIKWNSTDATILYQYKIDAKEIESFNDKLYASVLSPDTREYYISEIDINSNNIVRNYTGQFFERLYDMRFTETSLYSLSNKFVISWNRMTGEQTNRVETAGIIYGLNIVGDNIYISYHDLTFIEKWSLDFTNKETVNNVTPNGTLWTCRQNSTIVFGSRHNYVTVFDTIKGTIKKLDYDLSKIGKPRNVYLQDDILYIEANGYVEQYNINKATTSLSNKNDNKISAGFRLENFKLLFLCIIMLKFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU96</accession>
    <name>A0AAD5XU96_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006443</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000556">
        <property type="protein sequence ID" value="KAJ3215263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU96"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053044">
        <property type="entry name" value="Metallo-hydrolase/TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345:SF1">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="38613" checksum="F404F0AAE9412BA5" modified="2024-05-29" version="1">MNWKKTIDAHSHLPESDLNVLKNSLTDLKINKFVIMGTSPKDWPIVEELAKTFPNKIIPSFGVHPWSSEQLPENWFTELESYVDRHPNCLIGEIGLDKVAKNRETNVKYDFKIQEEIFEKQLVQCQGKMLEILQKKIKQVEIDKEEKKKFGKINFMMHSFNGSNDILSSLLRLKKNDLFNFYFSVSKIVNGRREEEKWREAIKLIPDERILGETDLGGVIGVLEKALTDSYEMIAKSKGWTLEKTCDILHQNCERFLNKSIECEKCGLKFRRLPDMYRHKRSVHDGGKPHNCENCGKAFARADGLKNHLLTKGNSKKCSAIKTFNSSYIPNSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUG5</accession>
    <name>A0AAD5XUG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Gag1-like clamp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RER1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000514">
        <property type="protein sequence ID" value="KAJ3215884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUG5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025124">
        <property type="entry name" value="Gag1-like_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004932">
        <property type="entry name" value="Rer1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743:SF0">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13259">
        <property type="entry name" value="clamp_Gag1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03248">
        <property type="entry name" value="Rer1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="624"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Gag1-like clamp" evidence="8">
        <location>
            <begin position="746"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="870" mass="100164" checksum="68473F6DB600E1A1" modified="2024-05-29" version="1" fragment="single">GTLAGVRGFQDPNVQMKKNKNSIFLQADKNSPDKVNNETILMPWLLSTYEGQCLTGGSNQRYETVMAWNSSNENTVEILGVNSMSYFDRSGIPFYYSLADNYLIGDNYKESVMANTCPNRVVYMAGTTMPERDYNGKNIPVESNSVQNKPYMDWETFPEHLEKHNITWRIWQNSLDLYDSNALSWFEQYQPKNNNTALIEKALTFFSLAEFQKACANGTLPQISWVISEQQLSEHPPWLPNSGEYFISQVSKAIITGKHANSTAAIINYDESGGFFDHVDPEVPAFGTPYTWVLKDRLFKNQPAPVGPGPRVPFFIISPYTKGKVVFSENSDHTSTLLFLEQWVLAKFQINITFPLISKWHREHMSDLVNAFDFTETNLTMNLLPTVKKPQQNVFTKVFVSSELCLTSQHFNGIPTPPYKNQTFPSVEAGFRTVRGYPLQGRFFTLESGKFSLTTYKYEVQLRPTIIKRNDPQQLFIFLETYGEKNRFKIKSLKVKNETGKSYCLNFDLNLVKCAIAPIWDFKMSEEVENNQGYEITFQNKYFLLGISLLMQNPTINLQPSTPISPSGVDSSTTTAAQIQRQAQWTQMRYQSLLDYLTPLTTFRWTTTVALFFLYFLRVFTAQGWYIITYALGIYLLNLFLAFLTPKIDPSLELDTDPNDEGMSLPTKGNDEFKPFIRRLPEFKFWHACTRAVTLALLCTTTRATDIPVFWPILLMNSTNQSFWEELIEKQGSSINADKDNKTEKNFEETKSNFELPTFDEDNIGIKYWERIRTNWTANHEPFNPILHRHSTMSLPSSPKKQSDLLDSSNLKSNFNLNSNNDRKKLLQHIKKDHYDLIYKNIISQRSFSEPVPLDFLVKVLVHGWEKEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUH4</accession>
    <name>A0AAD5XUH4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001959">
        <property type="protein sequence ID" value="KAJ3200160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUH4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3200160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="50408" checksum="D8A485DD15B99DD0" modified="2024-05-29" version="1" fragment="single">NRYFIEDSKKKMSNLSTFVTIIGSASTFQESSSTLINQLETLQPTIFQESSIFLSTSLFSIATISSTETVTTTFTKSKTSHSTTNSNPLGDVIVPKWDPINTTETPIISKQIVTNNRDLIIYSVVGFTLLLIVFGIFLCIRKKNNKKKELFLQSKEALKAEFMDYDDTFEKSLQSYTMKDAKGTQDNNEPPSLQNASGDESKDVKENSFFPATTSVNSNFRKLNDKHYKNFENMQFENFENQDNFQNINYETVSLSASASFSQFQDQGLSSTHMNPNFGNTMNKNIVIANSVISHNSSSTNFVNLSASTDINEIKYFNTSPSDFNVTNFNANELELFPQQSTSIVNSTSHFPLCDLKAELPNLGCSPLLVTNRLSQVLELDNVELAERTSRQDSLDREKQPNSFIDNPQHDPEVRILTVFAPYEAKNFDEITLIVGDEIILEKSFQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUW3</accession>
    <name>A0AAD5XUW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Autophagy protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ATG18_1</name>
        <name evidence="4" type="ORF">HK099_005511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000431">
        <property type="protein sequence ID" value="KAJ3217346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="240" mass="26909" checksum="964A518047A96CD6" modified="2024-05-29" version="1">MSNMSQIEIIECRYSENAPFALSPSSNNCYIAYVENGKVNNGLVHIHDLLQQINVKVIEAHLSPISYLSFSFDGTLLATSSDKGTVIRVFSIPSGTRLFQFRRGTYVAKIYSISFSPDNNYLCCSSDTDTVHIFKLDSVNNSDTFDLKTNTIEKNLTPVNALIPTSVGSLWELKRDFAFCKLPFSQKTLNVKPNLPVFNVCSMSADQCVSVANFDGRFYKFKLNTIFGGECFLLREEILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV13</accession>
    <name>A0AAD5XV13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001402">
        <property type="protein sequence ID" value="KAJ3203628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV13"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="175" mass="20444" checksum="559FCA49802C3D3E" modified="2024-05-29" version="1">MNPFKYLGSEIGLMKNEVAPKNAHLIDDDKYYVRDPIFIAPKIYGYKTLDDKEIIKCKGVSKDMNMIFYDLKALYNELKKSYWDAITDPGYDSDQDCNIENKTIMLKIVNFTGDPSKYNFIKTQEVASIEEETKAENNESFTENWTYIDLYNDISSLNNYINYAPNIYYYKTAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV60</accession>
    <name>A0AAD5XV60_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001116</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001299">
        <property type="protein sequence ID" value="KAJ3204444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV60"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106300">
        <property type="term" value="P:protein-DNA covalent cross-linking repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="entry name" value="SOS response associated peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604:SF0">
        <property type="entry name" value="ABASIC SITE PROCESSING PROTEIN HMCES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="DC12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="BB1717-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="157"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3204444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="23450" checksum="6D50BA5567F269A6" modified="2024-05-29" version="1" fragment="single">MREICGVFPKIQKVANGFFEWKTEGKLKIPHYISKEIKDEKDEDTLLYFAGLYDDSNKEAPTYTIVTVNSSKYLSFLHERMPCILDKSDIDLWLDENKKFDSDIEGFYPVSNAVSKRVNEPENIVEIKREAEKPKSNKNKNQIDFYFKKKPEIKKEKKLDGKDINDTNEAKNADAEKEIKEETQKRKVDDDNDEKVKLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVJ6</accession>
    <name>A0AAD5XVJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000332</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001072">
        <property type="protein sequence ID" value="KAJ3207205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVJ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF8">
        <property type="entry name" value="NAD-DEPENDENT HISTONE DEACETYLASE HST3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="6">
        <location>
            <begin position="174"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3207205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="422" mass="48138" checksum="80988D58C5D4DEBC" modified="2024-05-29" version="1" fragment="single">MSDIKFGKYRQIYINNLQYSPQELESLIINLQNDIKSSSLTHYENIEKNYLNSKKNFTANCNLCGVIFHNRKRFKMHFITTLHQKKLGVPVIYMPIIEVMEDLLNRSLLWHDFKEIGYFQGRTCEPKIKEHQKYKETQAGENSKKSTDAAVESSEKLTHAVKAVNNRMEIEGCIKEDNRAIHSFTMAIKTAKKIIVVVGAGISESSGIPAFRNKSGRYTFQNPLSKLKGKQTMDALCVFGSEKYFHGYINQMAEIWELSKNAELSSVHVFIKQLNEENKLLRCYSQNIDTLEKRFLGDNKLTLLHGDLDSLICIKCRITVPFTQRLCEDFKNSRVAECQNCKKYSKQCERKGTLDAISSDAKNVDMLVVTGTSLSVPGIKHLVKHFCASVTAHAGKSFYINYSKPPSDIKFDFHISADANEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVU3</accession>
    <name>A0AAD5XVU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000936">
        <property type="protein sequence ID" value="KAJ3209516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVU3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3209516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="545" mass="61991" checksum="68DDBBD20DFED607" modified="2024-05-29" version="1">MLFVGCAKVFDHEAQTYEHCLQAHSLAGKQLCQWVSNHNFAGCGYKMNHKGQLRDHLIMHFSTDFRPLQCSICLKNIRSRQELNRHVKSHFKASDNENSCESAAKSEISVNDSENITNQTSTEIENKNLNKKNDGTAMDLDEDPIIFNDNNNNTSLVDDEAQQTELSDNLKDLINESLNSHLLFVENLYTIISNQNNERTKNNEHTQNISLKNQKHTDFAIASLFTKNLEVGNNGSPKIHVEQIMEHLKYSLSRHSLLLPINPSSSCVVGTNLGIFWTNYDKVLEKLQIAYTDDIKVSLTDSYIKDGAMGRIGQPSKKYFLDALVSSPNYSQNECINCLVEIVPNSIKLLYTPFFINLSRALLGEIKNIFKDGLTIKGDTSFLKPTYNPNFPFKRLLMTIGETIKSCLEGYLTNEDTLNFYEPTVDSPLYRHPSDCTAAALLMNYKQAFPSVAKYNKIFLQSLKQVLKLGVDEIVKKLIYSDSQIGKICRKTCCFGFLCSGAVRFNWDIFCFEDESFIWFRLGVDENFILSPIKDLDLNFESVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVX3</accession>
    <name>A0AAD5XVX3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">HIS1</name>
        <name evidence="16" type="ORF">HK099_003957</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000269">
        <property type="protein sequence ID" value="KAJ3220845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVX3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000082">
        <property type="entry name" value="ATP phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403:SF8">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE ATP-PRTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="14">
        <location>
            <begin position="70"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="14">
        <location>
            <begin position="109"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine biosynthesis HisG C-terminal" evidence="15">
        <location>
            <begin position="218"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3220845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="286" mass="31010" checksum="6C55E950B0A2C838" modified="2024-05-29" version="1">MESSESIDASANLLKKDAANNLLFAVPKKGRIFNKTMDLLKGADIKYVRKSRFDIAYSSNLPITLVFLPAKDIARFVGDGNVDLGITGQDMIQESGLSEAVDPLLDLIGKRIVTSFVEITKKLFMELETVAVPENLTTKISYVSGSVEAACALGLADGIVDLVESGETMRAANLKAIHTITSTQSVLICNRKKHSQKNSARSILIEKIFKRIRGVIEAQQFVLVNYNISQNDLAKAVAITPGKKAPSVSKLDEGGSYAGWNAVSAMVQKEVVVDVMDKLELAVSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVX4</accession>
    <name>A0AAD5XVX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000274">
        <property type="protein sequence ID" value="KAJ3220778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVX4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="173" mass="19257" checksum="A57C11E145638DA4" modified="2024-05-29" version="1">MGKCQCYCCDARNCSAVLVGSFSATYQFECMSSSCMAKFSSCSVPNDVNVNGKVQANFVGSTEYFYISWPFMFVISGAVILLLCSITACIKSKTRQNQLLVQTITPEMTPEMTYPPPNYYYSGQQRYNQPYRDPFNNNMPNRAAGPADEHNACQYQTGGQNYFQTGRLNGGTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW15</accession>
    <name>A0AAD5XW15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003845</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
            <orientation evidence="1 6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the clathrin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000259">
        <property type="protein sequence ID" value="KAJ3220976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW15"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00581">
        <property type="entry name" value="CLATHRIN_LIGHT_CHN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="79"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="84"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3220976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="135" mass="15680" checksum="B972450749C514E8" modified="2024-05-29" version="1">MWRIEFEETIQARDSKSKARRDNTLKEAKESLERFYAEYNDKKEKNLARNKSLEKNAEPESTNVWERIVQNIDVKTSTAALSSRDQKLKDKLQGKEKKTDEKKKAPATKGKDRERMKQLLISLKKDPKAPGVTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWE1</accession>
    <name>A0AAD5XWE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000719">
        <property type="protein sequence ID" value="KAJ3213357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWE1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="22039" checksum="E01363E1EA0B611B" modified="2024-05-29" version="1">MNPFSTTTTKRFQDFTLLTPSRSEEEDANREEEDYLKYGLDRYFSPAPTDSNCEFKLNDNYFNNNLNFKSCKEFSSNLEEVPLEENDLELEEEIYFKENKTPQDYKKCKEHIKPKVREAFAELNIVDFEEHKKNIGKYYVDEYEVFLVKSVRSRLPTVNTTPSLKKSVRSRKIFNPKIKIATKKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWL7</accession>
    <name>A0AAD5XWL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001772">
        <property type="protein sequence ID" value="KAJ3201165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWL7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="56" mass="6374" checksum="5D7926F8F1B2A57B" modified="2024-05-29" version="1" fragment="single">NESTSQQTAILTKKLNTVISNQLVQGIVLKKLEQQLMMPCRNYCEELSKFYVKGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWQ0</accession>
    <name>A0AAD5XWQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2 9">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RPO41_1</name>
        <name evidence="13" type="ORF">HK099_002606</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 9"/>
    <dbReference type="EMBL" id="JADGJW010000188">
        <property type="protein sequence ID" value="KAJ3222173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001018">
        <property type="term" value="F:mitochondrial promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024075">
        <property type="entry name" value="DNA-dir_RNA_pol_helix_hairp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046950">
        <property type="entry name" value="DNA-dir_Rpol_C_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 9 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="PPR" evidence="8">
        <location>
            <begin position="730"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="12">
        <location>
            <begin position="882"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="172"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3222173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1890" mass="218309" checksum="E7F914034858AF17" modified="2024-05-29" version="1">MVKRKSKKTNSTESVEVKSNESTGTDVLKQNSNLNTSKRKKRKSEDLELVEEDDVFNLNFENKKKQKNLINSSNKESSNKESSNKEKTKKVASKQSETKKAKKSTSKEKTKVTETVSVLQVAALEEETDLSTSMSAKTPKVLEETSKEMPKNEDNLLNTSKSIKDLLSVQMQQDLTLQVSNLQEAFNNLSKKVFCNQEQEEAVLKGRNAYQNYVKSTELKFEEYEKLISSLQVENEILNKNVSSLKKELSEEKLQFQNELETTLNKFKAKEETLQKDILEKEEEVVVFENELKKYENFVLEKILKNQKDNTVKGNQHDNVANETTDYSDVDFMATLEDSFALMESEILDLKKKKNQDQKKESEVGEEKMIFGKSNLKLADAVKFYETCTGMKIQSITEEVTEPNGEVLSNNMNKNEEKITKCKIYKILHESQNRVLRYTLSGPNFENNYFYKPNLTIDSSLTRINAGDDNSNNVSNIPLYLNEEIIFQDLNKFFEKCLNWVMMGSEKKNQNFNFEESMIRIYRYLTSKNSASKLKSSKNNCLLFEKYFTSTPIFSQEQHQQQNSNNITILPTLFPKLYNDISNDSKILSSTTYQGSVADKDGYWTDYKKPLPYEILQDKYSLMFILIEHGELMKAEMIFHKIYRSNFYDLQKSDTHTQLFNAFIDGFLKNVEKFKTQEDVKSELNELLDSQSAEVEDATTSTELSAKQKQNLNQALEWYDKIIRFKFKPNSETFILFLEAFCKLRDLEKVEEFIIKMQEHQLNPCDVLLDDRFSDNNEVSVIFEAALRKLGHNIDTYQPESDFLLSIVEEEQERNLRTESTTAFSPNQNKISSEGKSINLAKKTLEGMKVVKSTRSEGIQLLSAALKKLLQQSDDNPLTKYDQQTWLEEECRRISLIQNQSTSHNMPEFQVRSKLLFKWKMDMIRGVAEYIARARADESDEDYIYQYLLRVEPERYSLITLKAFLKVPTRKGENDEATFGDLNFTNVLNEIGRAVEQEIRIDYLKKKRNREKIKNDYNIYISHKKGKFFNPTFRKVASKITNDIDKKNSEKIWLPEMTTRTQILIGNILASILLDVAKVEVMNPETSEITLEPAFQHYIATKYNRQEGRIRAHPKVLEDIVAGDSFNSTPSALPMIVMPKPWLNVCNGGYFTEDRKIKLVKTNSRLQKNLLRDADRKIKLQKIFHSLDVLGSTPWRINKKTLEVILTCWNEGGAWPGIPSVAKLPPVEKPTDYKTNPASARVYRNELKKRNDAEKGRYSQRCDSNYKVLIAKAFENETIYFPHHIDFRGRAYPLPVHLNHIGNDLCRGLLLFDEAKPLGVNGLKWLKIQVANLYGNDKISFMDRVTFVEENIENGRRWWLGADDPWQCLATCMELVDALRSPDPTKFMSRMPIHQDGTCNGLQHYAALGGDVAGAQQVNLIPSDKPSDVYTGIADKVNEFVIRDAKSGVEEAILLQGKINRKIVKQTVMTNTYGVTFIGARDQVRNRLKEANDKNKLTEVQLEKCSLYVTKRIFESFGEVFKGASAIQKWLSQTAKLISECYNKTSLTQYELEEMTVLESLGAEIKSTYLGNLDEEKSQASRKKKSNSEEVEEDVISLNELINSAKLDNINVFNNDNNFVQVDSDFQDRLEGKKFRATSVVWTNPLGLPISQPYRNVKKVSVGTTDDKLRNKNQKSTTITDIDGEEKYAINHLKQASAFPPNFIHSLDASHMMMTAIKCKKDDITFASVHDSYWCHAKDVDHMSLLLRESFVDLHKVNLMKLLRREFLYRGKNLVHKVTYKLPMDKIEEWKKYIEKRNKEIVKNNSILKLDEEEDDFFNFNIEDFDSENSPSENNESTKKVNKPRVFFSSKFEKTGEVESYAEFKKLVTKLPNRGDFDINMVKDSKYFFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX65</accession>
    <name>A0AAD5XX65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000134">
        <property type="protein sequence ID" value="KAJ3223346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX65"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331:SF1">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="230" mass="26502" checksum="6285B361D957F981" modified="2024-05-29" version="1">MKLYFLKSRSNSNFAVSVIKSPVLKNQLLGYAPKINEIDHKTFVENKSFRKIINDTISKNIHNDVVLQGWAYQQKNGYLNIQDERCYVPWGRVPDPEDIFGTVLLSQGKIGKCWLLFRYINFNNALVEGSFEQMPTHRMVSANGMFKLSEYLESRLIEEVTTTGCCKESKIKHSRKRIKRHKNDNNSNLEGHVILITPDLITSQHANENVIINHINSNIVDKPPPAYEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX98</accession>
    <name>A0AAD5XX98_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA mismatch repair protein MSH3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 8">DNA mismatch repair protein MSH3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MSH4</name>
        <name evidence="12" type="ORF">HK099_000890</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001222">
        <property type="protein sequence ID" value="KAJ3205231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX98"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000003">
        <property type="entry name" value="mutS protein homolog 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000870">
        <property type="entry name" value="MutS protein homolog 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF21">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein MutS core" evidence="10">
        <location>
            <begin position="211"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="11">
        <location>
            <begin position="528"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00073774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3205231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="788" mass="89385" checksum="726EB15D6EC32362" modified="2024-05-29" version="1">MLSRSSSGGRSTGRKSSSRKSRPTTSLSSSRRNEGIESCFVMAIVEGRGVQSEVGFAAMDIRTSECILCQFADSQSYVKTLHKLYLLNPVEIIFPNTTIEHNNSKLVKLIEENFPEIDIIPFNRKYFNETQGLNFIKNYGITPNSSILQNLKNKFFSVTCTAALINYFEIVESLNFSNFTIKFKYQTIDGLMMIDSLTAKNLELVSNISDYKGPTLFSTLNHCMTPMGPRLLRMNILQPLNDEATIEARLDAVTELLKEENFYDVKNNIKSFKDIDFIISSKHTIKLIEPLRTCLSHSDSILLKSIHNVLSDKRISFIEERIDEVINEDVTYQKTSLGLRNQRCYAVQAGFNGLLDVARQTYKETTNDVYDLHSSLVDKYDLPLLKVAYNPTAGFHLSLPVSCVTEEMPAEFINVNKKSKQYNFTTLKILSLNDRIQESLNEVYLMSDKIISELILEIRKNIQILYKVSESISLLDLLMSFSIYCTQISECVRPEFTDTLVLKKSVHPIRDFLGQEMISNDVYASEAENFLLVTGPNMSGKSTFLRQIALITILSQIGCYVPCEYASVRLADSVFSRIGNDDALEANASTFMVEMREMAFILDNVNNKSLVIIELGRGTSNADGIGITLAICEELIKKKAFFFFATHFSELTTAMSIYPNCINLHLEVDIVGGNNKAFNFLYKVKSGESQEKHYGLKLASLAGFPKSLISRANTISNFFENRNEELKKSNQRSKKEKLLSLKIKLIERLVQVKKSSNLNEDDLNDYLKLVQQDYFNDLQVINNEKELC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXX0</accession>
    <name>A0AAD5XXX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004923</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000364">
        <property type="protein sequence ID" value="KAJ3218817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXX0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041936370" description="SHSP domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="47"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3218817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="158" mass="17550" checksum="5C62E3F4E3087310" modified="2024-05-29" version="1">MLGFLIKLGITVFVLKKVFNYKDTKKRICQKDHLLNRSIPVIQGWAKELSEAAHGLHIVESETSYLVSIDAPGIRSTDLKIVIEDDLNKVKVTGTTLNPPQAERRVDTTVTLPANVDLKSLAAHFSDGVLTLEGNKLISGRQLEVKATNNDDIQYQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY91</accession>
    <name>A0AAD5XY91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000050">
        <property type="protein sequence ID" value="KAJ3225866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY91"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="268" mass="31346" checksum="BF8FD98A0CEACC42" modified="2024-05-29" version="1">MATAKELVPSPDSLKMNWEASKNKDFMERKSYKKFSSSTTSQKQKEKEYSPSLFIKKNTKNCANKYESISNLRDKSCVQEMLNRNQNLVDNKTFMNSLSDKGAKLLKKNEELRSILDKILKYEKEVVLFDDLEKNFRKVTIKDNKISSKQENSTIKKEGKIKVIPLEESIKLQNARQAEIRNFFFNSKSLVAQNNQNHSQSSFEFIERSNYKELMKEGKGFEKYRNINDSSTEDEDDDEWEEDGYDDDLIEEEWESDEVIVVEGTVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYL9</accession>
    <name>A0AAD5XYL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000478">
        <property type="protein sequence ID" value="KAJ3216443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYL9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="204" mass="23480" checksum="764B1C5A34BC307F" modified="2024-05-29" version="1" fragment="single">MRQTRVEQYWIQTITTLPAEIVPTDSLYFTADGWVQPYKVGGAEFYFPTTLSIKKNEVIKDEDDDADTETTKYLAKGRNKIRNKDVKRKSNILPKKNTKEAGQLNLGDIILAKITESEKQDKKNKLENMQNEIKKEAKSNSVQIETEVRAESRICLERECVSEKAGAENYLKFLKSSSLNKNCVDRQYCQIKDTCPFFHPTKPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYQ5</accession>
    <name>A0AAD5XYQ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007048</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000652">
        <property type="protein sequence ID" value="KAJ3214070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYQ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042295310" description="Thioredoxin domain-containing protein" evidence="6">
        <location>
            <begin position="17"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="539"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="8"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3214070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="576" mass="65749" checksum="CE071A14B879937E" modified="2024-05-29" version="1">MSKLLVVILLILKLFARQVTFAEYKIADAQIDFIESKDFNTAIEKGNWFIFFGASWCGHCQAATPEWLDLQTIYGNSFKEHGVLIKKVECTRNQDLCESQNLDGFPSFNNGKKITEFEVGSGIEKTPTLDTLYKFCLQTLRGLNSGQHFEISKSVKKNDVNLEKIYDELKEMSIRDSKPKNNVNPDGRVVYLTDASFDKLSPVMDSLAPETKNYVNIAKVDCTVEKATCNRFDIRGFPTLKFFQDGEFTSNYNGARTLEELKKFSLGFLKDPAFTPLKSKDVVNVLNENEVSFFFIYTPDDDGKHKDQLETIYKAAKKIGQKHKVFVSPEENIIKLLNINLEQNKNSALVVLKENGKSKFQFESDVSSSNLSKVLEWMNRYKNPLIPVMDSENSEALLGGDHILLLSILDFTNKNENIQKELKTFLKSIDTSLAKNPKLIKFAMLNGKQFEKYVRNTFKFELNDLPKFVILDNSNEKYYDVDKNNKHFEYKVNDLMQALNDFNEGNLVGKYTNGYFAYLMKSLSNILRPYLNFIVNHPIISGILGAGLIAAFFYWLISEDTSVTNYQPVKTGSKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZC1</accession>
    <name>A0AAD5XZC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45532">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45532:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="289"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="571"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="675"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1209"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1401"/>
            <end position="1428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3228090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1714" mass="195131" checksum="745642328838EFAD" modified="2024-05-29" version="1">MPDLKLGSSELFNKKIKDFDSAEDLHNNYDDSLSIIPWISVKKCISSSLPKSLLPVIPVNVDATPKSRTLIVKKDTQTHAQSITLPHGFQLQKQIFNVSHDHTLSNIIFWDTAIVDTFSTLDSRNCSVIRGSTKVLNFLISNESQQQKADDKNNGCTGLNNWIYCSKWKCLIASTTHLELKILDCNMKVLTSTSSFKPVLSLEFANGCEELIAGCVNSIRIYRFKRLAVRGRYIQTFANTRLVIDDFGGDECWVTKTLLHEPTGKLYASVENHLYIFDFNTGEKLNCMKNIHVLSITSLLYCEGVQYLVTGSKDGCIKVWNNNGYLVHTLKDQLSITSLLHQPDISNKKSIKLLQLQQQQQNFILSSSLDGSVCLWDIDSGALLNKMESANECVGMGKLKKDFFFYFSKSSIYIYNITKAWQTFSTLRSSGIQITRCYNGSGAARLLVVAIDGSLRLISPLSGSILMTGLPVMEDFEPVTAVYNINFDKIWLLLKNGNVAMYDCSSNPMSISGQWLNLNNTGDKCTQLVLYEHTSTAMRTLKLMDTYTIFGATEAGQIVAFENDGKQHLLVQAHTAKISSLILDKKRNQLISSSCDNSIKIWSIKCQEVSHASHQPFILRLVLVIPLLDSPTRMALNNISDFSNLLAIVTDTYKTLMIKINSDNSYSTFKDHTNDENHIREVTCVAGNNVLNIFVTSSYDGTIKVWDGLENVLIREVQFNEIVWSVEFANPRGDIVAGVGDEIVLIKVQDYLPYHIQQYILNLEFEDDLLEMSLMFDPSLDFWDLYRKLLQEAGIEVENWHIDICENKKNSVSSNLLSKEELEKRIHVINQRRNKRLFLENERMHFETAKDFECTTKFSDNILELSDDHREKASCDLELEERQKRIDVYKARARRKLHDKRTITFKDLMMDDDVVQILNDSSQPSPELEENQQNSVGTKKKECEFKFIDERVSNRFLNGFKTDLTRKASIKFEQTSVSSTENDGVLKNTKIKSIPVTRKPLLAHAESFVFDINTVLPPIVASDADPNGFNYDMLDYKGGLILDKPAGLKMNGSEVQDLLNAENIRAQKLLQVSAKETQKKIVQKLMSTGSMPNSNRIKDVNEELLNSGERKRKSKLSEKFKGALKFDNQKEELNRPKTLSKALYERIQQKKRELALKETDEGHSYVEEDLTNFSTSFKDSMLKKETIDNNVVFSGPPFSVEKKLVELPVKNQDDQPDSPDMKEIENNDNNSEEGYVSDKSEPHVIKSKMVPVLKVSKKVAIKKRKRAPGTEYILTSSDSDTDSTLDSVESEEEIISNHSSEHNQVLGLAEKNLLLAQYREQERRKLEKIKKRNKESKVKEKLIKPMIKQVDKMEDGNLMKNTSSETKNAKSLEQTNFTNRNDNLDNSFNGADNRESLFFEKEEFSGNRSAARENLESLERSKNSLEVSCGKVGRSLPKEYLEAEKESWQFLKTIAVEKMKGLRQLTNETVFKEVYKEIEKKAWFPGLGDKEVNLENIVEVLFKVLDTGFWKEKIEASNAIHSIYCTFKEDFCNAESKILRPLIEHTMDDSPKVRANICCQIGKIAIYDECAIAALISRLKDKEKLVRESAKAALECFGIFGKLQLKETMMGLNILKSDKKFDTHSDWLDILLKKLKKKEREDIKFQNSACYGWRRNFTEYDFGSERPTTNQITLNFLPSLVANTSSKVIKKCSSEEDLSLPKIAKSYLAMKDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZN7</accession>
    <name>A0AAD5XZN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000304">
        <property type="protein sequence ID" value="KAJ3220433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZN7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="376"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="473" mass="54627" checksum="E9918EB886C75527" modified="2024-05-29" version="1">MAKYSPSQLVSFASKGKLLQNRQAEQAKFDICGDLPLNSYLTSNSFNSTKVLKNSKWKKFSSIDYKPENRGFKLNIPIDIKEDLNYENPTPSSSKFDESNNRTIKDEKDLRYEKNLKLYESLKHRNARRNRENDTDTSKTQCKSFARKRDKKPIFIKKEIKEQKKVKLSDNNLSLKSPEDLPHMLKKAKYEIIVDLGCSTLIENNVAKSTSILPSLMASDKLIYETNLKKFELILKNRKNFLKLKKGICVNKKMLCESEKDNNLKKELNAVIKSEFIFNGSACGSVKNFFKKEMSNIDEMEQNGNLTSKEVDQKQQLDSVKLDNLNGAKYQENLKIFETFMSRHVLNKSNSNSFTNNNAAIKCKENSLKNCKIVFNHDLKKEKEASEIDMENLENKKKKLQENLKETALKGLILKETIAVYQENSKMFGNTLQKIQVKSINDVKKNFFGVGPRVEKDHLYNISNFSKGMHRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZQ8</accession>
    <name>A0AAD5XZQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000395">
        <property type="protein sequence ID" value="KAJ3218115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZQ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="422" mass="48444" checksum="2125524FBD8F65AD" modified="2024-05-29" version="1">MNLLYILLFALILILLPIVVYIYFSKYWKKTNSIPDLESNAVNEKENLQEKYHNDIIKQHQKNNSTLVYKVQLYKNSDEISNSLNLKSLQFIPPTLDNITPKIDTCDKLELNIGTDTSANSPTSSTTSSSNSLTLENYSLHSMEDLKNSSVESSESYFSEFGKGEKGDSLDLGLDSEVEPLNNSQIKNLEFENVFDALEDNTFDDLNLSKQVDFTRNYLSLEDSKIFNLEEQKFNSSFDFEFLNEFSNNGNHDKCSDPDENIDYFDVNFNFEKSLSSKGGDTFLVSPQQSIQSENLNVNVEVENVPPPIPPKPTVLFQDSSNNMACELQLPSYHEIFHISPLSPNYNKYLLEHKRYKKYYGPRNTLKVAVIIRNATKLTWKHHKFNYGESNNYNFDEEEDDCGYYSSDSDNDSNDDDSSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y144</accession>
    <name>A0AAD5Y144_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y144"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="166" mass="17509" checksum="B2DD7B986ECDD2A1" modified="2024-05-29" version="1">MYVENYYSWPEKVQDIITTITKAYEGRIGLPDFAPVPMGGLPYGMPRPPLPFGVIPPNFRPPMGPGGFGMRPPFPPPPGFRPQMGFPPGPMPPPPGAFGPPGAMPPGMAGPPGMQGPPGMQGPPGVPAPSGMPGPPNIPGRMPPNLQNGKRAGEDTNFDSKRMRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y165</accession>
    <name>A0AAD5Y165_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000197">
        <property type="protein sequence ID" value="KAJ3221993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041093">
        <property type="entry name" value="Dis3l2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17877">
        <property type="entry name" value="Dis3l2_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="3">
        <location>
            <begin position="981"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="489"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1485"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="530"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="571"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1587" mass="182702" checksum="DE164AAC0B3C7B3A" modified="2024-05-29" version="1" fragment="single">MEQDFFITSSLPSGLTITKKCKADEVNHSTEIDTPGKLYTQANKKQPQNKNKQKLAASDDSNVSSSYLTVEYVKKKTDTPYDPVTKIYTPSKFKVIREKKIIGNNCEAVTDNSVEVDNKSETSLTKNKNVENTLTEAIPFSTSKHHSEHQSKSSVQFFLKKLEPNEKQLIRTSNSNNKFDDRLKKCFKELSNPELVSTAELIRRRAQKFEEEKQRLRKEVGEKEEQKKQPEEYKRRKEKGDKLQTERDNKKLHRKQSNQKMDDGIKEPNDKQHKEDETLQLGSQIKKEIKFNPGIQRVERLNSNTGIQDDKLQPALQHIKESKFNPGIQRVERLNSKSGIQHKEDKLQPALQHIKESKFNPGIQRVERLNSNPATQDDKLQPGSQIKKEIKFNPGIQRVERLNSNPGIQDDKLQPALQHIKESKFNPDKLQPALQHIKESKFNPGIQRVERVDLNPGIQHKEDKLQSGLQQKKEIKFNPGIQRVERVDFNPGIQHKDNKLQSGLQQKNESKFKPGIQRVEVISFKSSIQHTEEKMQPGKQHNEEDKLEMSEQHKEKDEVQHRSKQASLKQQKKEDLMQTGAELKKEENKMQTDVKQHNEEDKLQKSKQHKEKESECQNKSLSTSLNLEEVLTIPDSNIFPLAKSQQIKDGVERNFTKNKFDKYPQEEKIKNAKEETSADLRNTQYVNTSGGRGADADSWNRKSPELKTRRFSSQNYYADYWDDDAIAQGIMDGTVFRGILRINKTSTQESYCTSKNLNDDVFINGIKNRNRALEGDEVYVAIISGEELEKEKKFTEERNEKKTEIDIRRQKKCDFFDLPSDTLIIDEVAEERRANMAYGKVVKIISKIKSREFTGLIGTTYSFEEEDSKPSTARYFWFRPSDKRVPQINVASAYIPKEYVQNPKLLKNLLFRVAIKHWGPSSMCPQGLYRGKLGVMGEIGIETEAALINAGITWDERFPSAVMRCLPKTPWTIPESEVSSRLDLRNLTIFTIDPSSAKDLDDAVHFRHLSDGNYEVGVHIADVSYFIEPGSAIDVEAKFRATTIYLVQKAIPMLPRLLSENLNSLNPGVDRLAFSVIWKLDKAGLIIREPWFGKTIIRSRAKLSYEHAQAFIEGFSSWKEARAAGKQLNEVEISDGVKEEELKKVTLDLYALSVRLRERRFSNGALSLQNIKLWFSLNEEGNPVDCGAYELKEANRLIEEFMLLANISVAKRILLSYKSISLLRQHSPPSATSINNFIVHANNLGFFQFKSGETSSTDLQSAFDSIADDIKQKVLQLLCVKPMQRAKYYCSGDKELEVTDMSHYALNVPYYTHFTSPIRRYCDLMVHRLLYGAIKFKKGRGSGYKFIEGRSIVDDLTFKDEDFLVDPKKDEIKSLYQVENIAEVAKHCNIRKFSSKDVQDASQNLYLCAFLTKNFGGLNGRLDKETKLIEMAVVYKVGNRSFDVLVTKFGIEKRVWVEDLIDRELIKGSEYDQSEGSLKIYWKAFQSEEEKLEMKNNNNNKKEKNVDQQLDSIENISNKFQRLSIDYESSESLVQAEEEDFIQEVKVFDQIPVKVEVNMKGLKIFLYLNHPNDPDNNLNHDINEERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1F1</accession>
    <name>A0AAD5Y1F1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000177">
        <property type="protein sequence ID" value="KAJ3222398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1F1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="89"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="235"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="410" mass="47947" checksum="F0100FADA03D25C4" modified="2024-05-29" version="1">MTLSIISDLSCSSMEERRRDDRDDREDRRRDDRKDRHRDNGNDRHRDDRDDRHRDNGNDRHRDDRDDRRRDDRDNDNDSRRERRRRADHNDILSILKEDERFTKIAKIVEKSDVLSDSLRDRDVTFFAPTNMAINRFLELAKNIGGDSNEKHLEEIVKYHIVAKKVPLHEMYEGLLLETELTVEDLGKKHERQKIVVGKILGSVALNRLARVDELGLVSSNGLVHPIDWILVPPKKLTEQLFRFPFKCSTFVSAIQACDLVDVMSKKGLTCLVPLDSAWKQMNMNDLFYLFSPLGRHDLKKILEYHICDELWYAEKILENINEPIELHSMLKKEKIKIEVKSCIERKKRVKPEECMMVINDGEAIIKITDCVAENGTAHCISNVLIPEVVIKNLPSKRESTMRSFAELDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1F5</accession>
    <name>A0AAD5Y1F5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Photolyase/cryptochrome alpha/beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000934</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="6">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1F5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.579.10:FF:000003">
        <property type="entry name" value="Deoxyribodipyrimidine photo-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="8">
        <location>
            <begin position="12"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="268"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="310"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="408"/>
            <end position="410"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="395"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="502" mass="58473" checksum="971921001E44F0E0" modified="2024-05-29" version="1">MPLSKKNKLSSQTVVHWFRVDLRTSDNAALHLASLKAKRERMPLIGLYIISAKDWKRHDASNWKVNFILKNLSTLKVDLETKFSIPLIIKVAENIKDVYEILKNVVEKLDTKYLYFNQEYEVHENQRDEMVQAILDSVEVKRIHDQCIVMPGSVLTQEGNIPKVFTPFKRSWIKFVYQSPVKTFPSPEKSEVELQPLAEDYIRSNSTIPFPNHDNFLNDFVLSTEKADFFKTYYPIGEDSGLARLTEFVEKKIEKYKVTRDYPALEGTSNLSPYITNGIISSRTAFLAAFKKNNERLESGNENITTWISEIIWREFYKHILVGYPRVSKNKPFKLETDNIQWNYDEKLFKAWCDGKTGYPFVDAGMRELNTTGRMHNRLRMVVSNFLTKDLLIDWRLGERYFMQNLIDGDLSSNNGGWQWSASTGTDSQPYFRLFNPILQSKKFDKDGVYIKKYVKELRNCSGSSLHTLTAQLQSFGYPKPIVDHSTARELCLTEFKRIYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1U9</accession>
    <name>A0AAD5Y1U9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008627</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000097">
        <property type="protein sequence ID" value="KAJ3224304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1U9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="44674" checksum="10839E5E5909DE10" modified="2024-05-29" version="1">MEMKKKNFPAELMKEIIRVLIPPHKDGSILGENMTQYSSNTKELQKVLLAISQRYNSTCLAYNSLSVLDLSHLPNISSNDFKNLSDCISHVNTIETVNLRNLKLITDSSFLYFLERNTNVTNLSLETNLKLTEFGLANLKNKLINLEVLFIKNLSFFNEEIFFDLIQNLKNLKNLSLVDLKYLKEVYPFCFSSGDRSKPNLEYLRFTGQFNVQLFSALKCIGNSFSETLVGLRLNFDKSQEFKQEFRLIQKNLKNLKELWIDDTYYKEFIKLLDLKDYFVPLDNSNQLKLTLNMSINWLSINEIWNFLDYFNLNLNNLNFLIIKKKFYFNKFVFGENFFNHKETDNFLGEGFWNNYVKNVCEKENFGFKIHYQEYDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2A7</accession>
    <name>A0AAD5Y2A7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CASTOR ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000102">
        <property type="protein sequence ID" value="KAJ3224166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016540">
        <property type="entry name" value="UCP008459"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008459">
        <property type="entry name" value="UCP008459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASTOR ACT" evidence="1">
        <location>
            <begin position="46"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="118" mass="13113" checksum="A3CC8D81CB3CE204" modified="2024-05-29" version="1">MIPTANVSTIFESISSAKFFNLTQTSDEISVVVPATVNLLEYSAVEFNFRCFKVHGPLDFSLIGILSFISTCLADQKVSIFAVSTYDTDYVMVNEEKVDLAVDTFKKKGIKVIEDAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2U7</accession>
    <name>A0AAD5Y2U7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein PBN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005132</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PIGX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2U7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013233">
        <property type="entry name" value="PIG-X/PBN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040039">
        <property type="entry name" value="PIGX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28650">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28650:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08320">
        <property type="entry name" value="PIG-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00780">
        <property type="entry name" value="PIG-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 10" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3226301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="184" mass="20972" checksum="B27292B88FF0556C" modified="2024-05-29" version="1">MHPNFLIPAEVTNGADELILLILNLTTSAFVDKYQINNLNSVISLVSNKTDLEAPEFMADSNFNCFFMDLNSKFHKNGTLIPFHLRYHKPSFAGKYEEVKLNLPELYLIKKPTGKLSCNMNDFEVKKHFNQLESNFMKGEDNGLIFKVPIGVKGDIAWVSTLTIIFSTFGTFYLCYQLLSLPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSZ1</accession>
    <name>A0AAD5TSZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl phosphatidyl inositol protein transamidase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GAA1</name>
        <name evidence="1" type="ORF">HK099_002971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002019">
        <property type="protein sequence ID" value="KAJ3199874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007246">
        <property type="entry name" value="Gaa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304:SF0">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04114">
        <property type="entry name" value="Gaa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="117" mass="12939" checksum="12521F712ED5F656" modified="2024-05-29" version="1">MGLDTSTQKFEAIVDGNNITGINSYGILRAPRSDGTEAVLFSAPWKGINGDFNTQGSALLLSFAAFVTKFSHWSKDVIFLLPDHSLIGTQAFLQAYHGETPYSSQNLKYESLKYHVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTS9</accession>
    <name>A0AAD5TTS9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chromatin-remodeling ATPase INO80</fullName>
            <ecNumber evidence="5">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">INO80_1</name>
        <name evidence="7" type="ORF">HK099_002063</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the INO80 chromatin-remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The DBINO region is involved in binding to DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010001653">
        <property type="protein sequence ID" value="KAJ3201898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTS9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF2">
        <property type="entry name" value="CHROMATIN-REMODELING ATPASE INO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="98"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3201898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="27793" checksum="A24309D1D5E6A514" modified="2024-05-29" version="1">MDNSLNYQFYIYNPSRIGNLMFIQELSLISFLNRIEKAYIPAIIASPINVCCRDIRFSKIQQENLFSSELRKLFFFGNSTLINQTITSLITQSGKIQVLEKMLPLLKAENHRILMYFQMTKMIDLMEEYLTFRKYSYLRLDGSVQISDRKDLVMDWQSRPDLFIFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLITAGTIEERIMLRAKQKDQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTW2</accession>
    <name>A0AAD5TTW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">COG2_1</name>
        <name evidence="10" type="ORF">HK099_001958</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001608">
        <property type="protein sequence ID" value="KAJ3202188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTW2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009316">
        <property type="entry name" value="COG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024602">
        <property type="entry name" value="COG_su2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06148">
        <property type="entry name" value="COG2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 2 N-terminal" evidence="9">
        <location>
            <begin position="7"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3202188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="305" mass="34906" checksum="5ABF9B3E2318B7BF" modified="2024-05-29" version="1" fragment="single">PTTTPISFNRSEFLSTEFPSSIFLAARRNIPLKIVKSELNQTAKLLKLELVDLINKDYADFIHLSTRLVGLDKILTNINQPLGNFNSDIKSVEGDFYCLATVLERKLEERKQISKKMKILNLFVGVNESVTKVEDLIENCGKVRDSLIDSKLIERVAVEYIQLQYLFSDGKEYPFVKNREWRSNKIKDTVSNSLFNALKSAFIMVSLNANDQTALDSVNQLLRTYLLVDQVKHAEEVFSEVLVLPFVEKLFAKESFQTDKSDPSKNPPSKLELVYKNFIDYTEKSLYKVINCSRKSLRATSLISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU47</accession>
    <name>A0AAD5TU47_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001254">
        <property type="protein sequence ID" value="KAJ3204901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU47"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.700">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372">
        <property type="entry name" value="DAUER UP-REGULATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372:SF11">
        <property type="entry name" value="RE19971P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="278" mass="30294" checksum="F6883A29E612876E" modified="2024-05-29" version="1" fragment="single">KMTQTITEQISEKASEAYNAVHDTVFPPKTAGDKLDEGISAAKDNYDSAKNKANRGVDNTKAKVNDGVENTREAANSTLQNAKEQVDQTLQNTKEAANNGMQYTKEAANNGMQYTKEQAKNGLQYTKEQANNGAQYTKELANDGLEKSKDAINRGVQITKETADNGMQYSKELANDGMQYSKELASDGLKKSKDALNNGMEYTAEATNNGVQYVKKQANDSLQNTKQAANNGMEYTKETASNGADYVKEKVDNGELNAKKIVSDKSDKANNKVQSVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUG2</accession>
    <name>A0AAD5TUG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001259">
        <property type="protein sequence ID" value="KAJ3204850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUG2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF25">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="451"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="721"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="803" mass="91422" checksum="DB416F83CD530763" modified="2024-05-29" version="1">MQKIDNSPVLKSKLPISIILESHPVIKVLKDQPLKFKEIRDLLSSANGKYILFLPTQDACESEQFTLSFFENHVFVKNPENESQLISLKGLRGLLTNDHLIIVGPTPSEEELISLWDLNEEKTIQKEEKNVSKSLWDTYKDDNLLLQLFSPTIDFPQIPIHLNIPTKFLLDKNNNEEVYIEVILIKRMISDEDQEKINFQYSDPLINNKSSSSEPASKAVKSLLNAYNHKTNDTKIIKPASPLSPNPVNLFNYIPNIFSAANQPAKKNLSHSNSKSDVTSNVPTTLLPKVAPTTTTAPRLSSNISSLDVKLNFIEDLKDDENYNKFYSKFKNDSNLSFLLPQINDFIQKINEENYLKSTNSNLDKIGLESIEYKESENLKNFFESIKIKIKSINSKNNVFNKNVNKPNLSSDISTMEIEETLLQDVIDGLESFVLYSVYQSTFTNILRNTEKQDLNFQHKISCLNVLDIDFEYLISTENKNETSSSHSRVSSPDLSEKEVVDHRILKDILKSGGLEILKVENFFTPKKKIDTIVNFHQEILKRSGNIFKGKPTNKKSELKTKEVESSDDPLNLTKTKKTIYVNTVEKNENTGGNSADFLLPLLIYIIIRTNPPRFISNLTYITKFLQPKLCDGYRSYCLTNLLAVTSYIESTDFSTFDFPLELMKGPTIHQYNNTYLNLQQSLISSPTSIEEAGGNVLKGLGVIGSNIFGYIPSFRKNSVSEDVNGVPPPIPKRRSSMNKSNEDLDKTKSSRNSKVNNQTIIKEKFIEKELISFENNINLKQKATFEEENLVKKEDFIHDTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUQ5</accession>
    <name>A0AAD5TUQ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alginate lyase 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001100">
        <property type="protein sequence ID" value="KAJ3206769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUQ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042104721" description="Alginate lyase 2 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase 2" evidence="2">
        <location>
            <begin position="291"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3206769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="518" mass="57670" checksum="7EE941995E5CEA27" modified="2024-05-29" version="1">MLLKSFLVFATVINFISSSAIIRRDDECDGFAVPGSKLKCKFTTPSSEKGNYLRIYKNGDVDATADRSVRCPSENGEVSLTTTESDSGLWTVDLVNMDTWTVPATQTVELTKTPLIGKLQTLQVINVALGFGLKCDASVESGYNINYATAVRNVRCPLDGTAVSLVTEKTDNGTWTIDMVNIDTWTVPVNTIVSVTPRRWKLQCTSSGNGYEINCSYETRGAPNNNYIRIHQNHEFEKTEDRNVRCVEISGVVKINVGGLTGGTWIVEMVNLGSGVAVFGTTYTIPVTTSVDLKGWNLHLPVATSVGKITVIEEGVLYSKNFSYPPYFQVDTTYTLRTPVWFDGAASSSVSNVTGTELTEIRRWTPQIRRFLSFTGSINHTSEKGVVVAQIVGKYNGKDTPVIYVTLQPNAFNSLKWDLLAFVDEYDENNVKFNTITYILKRNYVFGATFQLKLNMVVGKLEIFYNGVLQNKDYNFQFEAYVYDKLHFRVGVQNLREASLDANVNKQVSEVTIYSLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV33</accession>
    <name>A0AAD5TV33_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001012">
        <property type="protein sequence ID" value="KAJ3208111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV33"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3208111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="66" mass="7429" checksum="0993D3DCDE0210D8" modified="2024-05-29" version="1">MAKYSPSQLTSFAAKGKLLDNESAEIAKMEIDDLSFGTFLTTDSALSRKTLQSTSKWHKLTKFFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV74</accession>
    <name>A0AAD5TV74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_002549</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48096"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11991"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61897"/>
            <dbReference type="EC" id="2.1.1.319"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010001851">
        <property type="protein sequence ID" value="KAJ3200701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV74"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070611">
        <property type="term" value="F:histone H3R2 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF10">
        <property type="entry name" value="HISTONE-ARGININE METHYLTRANSFERASE CARMER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="14">
        <location>
            <begin position="152"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3200701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="368" mass="42427" checksum="CA6A01DBADAC2548" modified="2024-05-29" version="1" fragment="single">MESVKEDFPKNDDGARDPSYFGYYAQFVHQQNMLSDIVRTQSYQRAILSNAQKHFKNKQVMDVGAGSGILSYFAVQAGAEKLILSNEKNLWLHDKIEVFQEKIERPLNIPKVDTIISEPIGVLLIHERMLESYLHARDHYLNPGGIMIPSTGTIFLAPFSDAGLWSQTMNKVRFWEQDNFYGVDFSPLAEDAKSEIFGQPIVGYFDYRLLMAPSVSYMVDFQTISSSQLKDFTIPIDWKFPFTGLVHGIAGWFDIDLGGVILSTAPSAERTHWQQVRFLFQEPLAVNAYENIHGWMRLIVNDNRSYHIYAEVTKNSNSLSEPSECLNNFQNLNLKRLEVENFRRGIWNLHEQTYHYETSPMDLSRPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVP8</accession>
    <name>A0AAD5TVP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001010">
        <property type="protein sequence ID" value="KAJ3208142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVP8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3208142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="75" mass="8477" checksum="306C8B80E0FFD9FB" modified="2024-05-29" version="1" fragment="single">DNYVLKTRQTIELIISSSIIQFRYNDLMVEKTIDLSSMEGLQKGIFKVGAYPCVNKADSESDSAEVMLFNVSIMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWH1</accession>
    <name>A0AAD5TWH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cilia- and flagella-associated protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BUG22</name>
        <name evidence="2" type="ORF">HK099_001789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001545">
        <property type="protein sequence ID" value="KAJ3202614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWH1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040441">
        <property type="entry name" value="CFA20/CFAP20DC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007714">
        <property type="entry name" value="CFA20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12458">
        <property type="entry name" value="ORF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05018">
        <property type="entry name" value="CFA20_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFA20" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="22629" checksum="075903383697D125" modified="2024-05-29" version="1">MFRNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSSVLEIIGTNVSTNFITCPAQQNRTLGIKLPFLVMIIKNLKKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDDGWNQIQFNLSDFTRRAYGTNYIETLRVQIHANCRIRRIYFSDRLYSEEELPPEFKLFLPIQKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWK2</accession>
    <name>A0AAD5TWK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFAP298 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000788">
        <property type="protein sequence ID" value="KAJ3212242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWK2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003352">
        <property type="term" value="P:regulation of cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021298">
        <property type="entry name" value="CFAP298"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13238:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13238">
        <property type="entry name" value="PROTEIN C21ORF59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11069">
        <property type="entry name" value="CFAP298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="407" mass="47018" checksum="5A654924488BA44C" modified="2024-05-29" version="1">MVFLVVKKLEQTLFLHESKTSEKISHLIPTIVQIQNERSRLGRLISAVEDLILYGPLKPEQEFGYDEDQLESLSKEKEQNFEKVLKVDEKGKSYLFNPDPTGRRNGHAPTEEQALILEKTLLNGKSLLSEDLIKANKVLDLLELKDVFENIKGALIIVFPEGLPQWETCLECLENREELAGSAASKDVLNLEEVSLWWASKELLPEKILSDYIGKNEKTKIIVKIQKKGQGAPVKEAPLSEQAQKEMMAYYYKKQEEHKKLIENDDDDYVNSAWANNRSLKSAFSGVSNGVKWKYITLIFNKKVKFLNGTTAKKDIEKFNVQKYVLNNHNFNSRRFFNKSKELQKIFCQEFHPIEIENSVLANITQLDFHISVLLKNDIVSDSILTKGGWEMTEVNKFLRIFKWRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWV3</accession>
    <name>A0AAD5TWV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001218">
        <property type="protein sequence ID" value="KAJ3205281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWV3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3205281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="62" mass="6903" checksum="05FF475E3CF7EA33" modified="2024-05-29" version="1">MKKMTTFTQSLSRKVTAINPNATGYEINNLIYTQKTISKDLSATAIDMQKANTILATWGKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWW2</accession>
    <name>A0AAD5TWW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-lactate dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010001210">
        <property type="protein sequence ID" value="KAJ3205372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWW2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903189">
        <property type="term" value="P:glyoxal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010646">
        <property type="term" value="P:regulation of cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0023051">
        <property type="term" value="P:regulation of signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03135">
        <property type="entry name" value="GATase1_DJ-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000022">
        <property type="entry name" value="protein deglycase DJ-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006287">
        <property type="entry name" value="DJ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01383">
        <property type="entry name" value="not_thiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF12">
        <property type="entry name" value="PARKINSON DISEASE PROTEIN 7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="5">
        <location>
            <begin position="8"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3205372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="20772" checksum="156A91EC5C474B59" modified="2024-05-29" version="1" fragment="single">METKTETKALVVVAEGSEEMETVVVVDMLRRANITVTLAALTVNPNHDYVTFSRNVKIVPDRYLEEIMDQTDFDVFILPGGINGAKAFKTSKLIQNLLETYLKDETKLVALLCAAPIALTPLTLQILAGKKITSHPSVKNQFDLNYYDYSEDRVVHDGNLITSRGPGTSCEFSLKIIETLIGKHAAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWW8</accession>
    <name>A0AAD5TWW8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001356">
        <property type="protein sequence ID" value="KAJ3203961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWW8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="156" mass="18047" checksum="CEED9C74951F949D" modified="2024-05-29" version="1">MDTKLLTKEELAVLTDYLIKGSSEKKNPYLDENVDPLYFTANLQVENSPQYLSDIYINQLLTDDWGRFNKLQKASFLLALPAYTKKFQTQKWTALALQLTERAKVDSNEEYVRIVGYIVEAALKNSKTVDYEQVKSNCPNFEKNCLDFENEGENKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX88</accession>
    <name>A0AAD5TX88_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010002040">
        <property type="protein sequence ID" value="KAJ3199771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX88"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF84">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="237" mass="26944" checksum="FC5D68DB3DD35DC1" modified="2024-05-29" version="1" fragment="single">MMDEFDLENDPEPLLSPKEVLWKCYNKVKELERNDGLVGSTTSLICQLKYDELSVVNLGDCGLMVIRDNKTLFRSEEQQHSFNFPFQLGTGSRDNPEQAQEFTLKLKENDIVLIASDGIFDNVFDDDILDIVKKCFFEFGNNINYNNPNTAGSNIQLDPKLFEKNLNKKIKHIFNTIDPKIISDAILLNARLIAEDNRANSPFSSKAIQEGIYFQGGKMDDMTCIVGFVRLDEDSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXI4</accession>
    <name>A0AAD5TXI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AN1-type zinc finger protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ZFAND5</name>
        <name evidence="8" type="ORF">HK099_006786</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000606">
        <property type="protein sequence ID" value="KAJ3214610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXI4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053061">
        <property type="entry name" value="AN1-type_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46728">
        <property type="entry name" value="AN1-TYPE ZINC FINGER PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46728:SF1">
        <property type="entry name" value="AN1-TYPE ZINC FINGER PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="183"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="7">
        <location>
            <begin position="656"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="359"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="505"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="505"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="534"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="554"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="586"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3214610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="722" mass="81127" checksum="B056460318A47C2F" modified="2024-05-29" version="1">MSTEKIKEIKFSFLLMAEPSNNIPNNVPRPPSTPLKGPLTNATRTIITRQKSEAVEAILQNGNLTNNSFKEGKRKISSQKLELDTNLITNSVTESQKDNRKIDFKTDLSSKVILEENNFLSKKSVSTLIEKKTLKASSKSSSSSSFNNLILNNEKNKKKILLQQNKIKEQKKNNKVEKEKKFGQVTVKTILGTNFQIKVDFFNIKFTVQDLKLLISEQEDLAVESIILVFGEKVLKDDKETLYNLKIQDGSTLKLVIQMAGGPGPPTRIKNPIKEDDSIVLLLCKQNEELYMLELHMKNAKQRRAAASQFFKLASLRPSSSTCQLLSEISGLTKEELCGNKSFEDFEDSEDNFDAEEVEEDYDFEDDSHSNNNFDTFGTKKSRPKSTQSSISTGTFLSMIGASSISAFNSRPGSAESITEEELFKDFYNSGSLFLRSAPMSAKSARADLACDCSKKNYKSAPNTGFEKKKLKLRPATAICLMRLPDLDTMPFVIIPSKNRITKSNESLIQSNTRPTSSKTNVDVEDSWHKKDITFQSKDTNNKTSKNENFLPKILSNNNSLSNSTISSTEDENKRDNDTQYKMKGNQDSSENFTTSNNPISTRKIKSSSSNMSCTSKKSSNTRISFIKTPLKKLKRLQTAVIKNNNSNKKPEEKSNIIKLKCEHCKKKLGLANNFKCKCGKSFCALHRYSDRHDCAYDYKAASKSALIKDNPLIISEKVLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXJ0</accession>
    <name>A0AAD5TXJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000669">
        <property type="protein sequence ID" value="KAJ3213871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXJ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="320" mass="36103" checksum="D76130906D17A11F" modified="2024-05-29" version="1">MNTSDFFTSTTTVTSFPISSDITSTSLSSIINSTSPTTSTITTPAIITTTTNDISTTKHQNNSYTSTSLVLPTSTITESISSTQSQFTLQPTMIPSDNNYNIKFFSPEIIIGTTIALLIVLIAFCLFIKRTNNSKERRLSTSKNIKTCEPTIDGYSSNISNEINYENTVDPKLKPNAHVEKYECFHKQHTSPHDQLPLFLSSNVPTSLYNEKQHYVENFNQQQHYIENSQYNEMTAQSSTGQEIVFIDKPTQYPNFYDSNGWDYISDSANPGSNWDYIIDNAEPDSTVYYKEPKLNYPSLYTVDKQEENSNAVENIYAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXW4</accession>
    <name>A0AAD5TXW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA-ATPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000568">
        <property type="protein sequence ID" value="KAJ3215117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXW4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018631">
        <property type="entry name" value="AAA-ATPase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012547">
        <property type="entry name" value="PDDEXK_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825:SF1">
        <property type="entry name" value="AAA-ATPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825">
        <property type="entry name" value="CONSERVED PROTEIN, WITH A WEAK D-GALACTARATE DEHYDRATASE/ALTRONATE HYDROLASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09820">
        <property type="entry name" value="AAA-ATPase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08011">
        <property type="entry name" value="PDDEXK_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA-ATPase-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="586" mass="66999" checksum="8BB30C7E9D485DB6" modified="2024-05-29" version="1">MNQIHVVKGNKLPIGIDSFRCLIANKYSFVDKTLLIHEFIKSSSLVSLILRPRRFGKSLNLSMLRYFFEKVPAETPSTINRRGLFSGLLIEQNHIQLFDTHFAKYPCIYLSLKGCKANSWKHMLRKLRNLISDIYSKHIYLESFLDDYEFQRFKSVLNCFPDFTESSLMFLSKILTKYHGSRCVVLIDEYDAPMEWAYNNNSENSNHEGYDFLNNAKSFFELLFSNLLKSNDSNIHQALMVGVVRVARSGFLSGFDNYCVYPMFSDRFSNHFGFREEETQTLLQYHPIPPAFNEIKQWYNSFHAGNNISLYNPWSIVNICEKKTLKSYSVETGGTKSIESLFELVNDDFKLNIASLINGNIVPRNIQKDVYYETLQSSPEESLWPLLYYAGYLTANSNGVKIPNLEVRLEWEGWFSRILTSKFPSLSPSSLLDLIINGHSETFVSKFPIVLQSCLTYFDVGGSDSGKKAEYFYHAFCLGLFVHARDKSFNVSSELPAGTGRFDVTITPPSAKDYAAILEFKVVKGGESIDVKSQEALDQIDLKSYRASIPPHVNKLMEIGIAFKGNSSHVVVRKLEKDGNDIWNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY89</accession>
    <name>A0AAD5TY89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000515">
        <property type="protein sequence ID" value="KAJ3215860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY89"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000964">
        <property type="term" value="P:mitochondrial RNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013943">
        <property type="entry name" value="Pet127"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31014">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION SYSTEM COMPONENT PET127-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31014:SF0">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION SYSTEM COMPONENT PET127-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08634">
        <property type="entry name" value="Pet127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="821"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="853" mass="97364" checksum="7FF57C52E1893258" modified="2024-05-29" version="1">MHEKKFLLHNPLKLLLENRNLKGNIFNLATSNFILKSIKKADETKIPFLKHDLHKCINSRHRFFYAKKAKLTSNIAQPDNFHYDRLPPYVTASKDETLLNEAVAAGASYYSSTSSITNLLVKMFILITPKKYVLFQAKNEKLPLKMPLTPVIRRPTSSIIHWRSPTLRAIDVERSTIEASNILMELGKSMEKMMVLSEKDYSYYLKDKEIPSTNVIEEDCFNYTKVGDFLIRSQIDCKYESEKSKARKKTLIFDLKTRAIRNIRLDVHNYKRYVTYKIRKIFGPRLTWESEYCDMLRSVFVKWKFQGKLGLMDGMFVFHHSTKKALGFQYISMKKIDRALCGSVAFGDFMFKMSMQLLNALLNALVKRYPTHNLRLTVDSSPVQHVILFVEPIPHTEKFVADEIETTKNDIIMFNVFAQLKNNSSKSSLTETEINNLKKNKHLSLDYSIVEITDISREKVLDLWSQTRKRCSNLNIEKTKKEPSLADNLQQLSKITTAVRSTNVEDISSANMQNASDLKDLKSEIDPKVVPEEEDTRNVRKNHIIQSVATGEKPISIQGDIISFISEFVKGAGHFFKRVWEPLKSSMPQSKIDNSLNEVKQKADGIKQKSAEDLQHNFKNNQNNDLSSGNSTVIEDSKVKDNAVFKDDSIKAEISALKNTTILKDDSKKSENSALKNTTILNDDLTIKDDSQKTANCLEKKKLRYPFNQFVESKADNIKPAKKKPHVGRKVIEDVAGNAVEREQSYLLQSVKIAGLHSKTVLSRGKTKTSNMIDEEKNEKTRKKVQCVSFLGDNISADPTSQHGRSKNSEKDALPNEHQKSQRTKVNSKKKLIVSNLESTGSGVNIGDEHFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYB9</accession>
    <name>A0AAD5TYB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000173</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001024">
        <property type="protein sequence ID" value="KAJ3207888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYB9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2030">
        <property type="entry name" value="DNA/RNA-binding protein Kin17, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056767">
        <property type="entry name" value="C2H2-Znf_KIN17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019447">
        <property type="entry name" value="DNA/RNA-bd_Kin17_WH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037321">
        <property type="entry name" value="KIN17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038254">
        <property type="entry name" value="KIN17_WH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805:SF0">
        <property type="entry name" value="DNA_RNA-BINDING PROTEIN KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805">
        <property type="entry name" value="KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25095">
        <property type="entry name" value="C2H2-zf_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10357">
        <property type="entry name" value="WH_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01253">
        <property type="entry name" value="Kin17_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="180"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3207888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="38505" checksum="CFAA74A50638D038" modified="2024-05-29" version="1">MRNSVERIKAMTLKVKEMIKRAAMVTSVKSDADFFSADSKQIKSKGLQRLRWYCQSCNKQMRDENGFKCHIATEGHQRQMQLFSENSGAYIESYSSQFLSAFTRLISSRYSQKPVLMNTIYQEYIQDKQHMHMNATRWSSFRDLANYMKKKGLCDYEDSDRGIIITWIDNSPHALERRAAMEKKEKSERSEEERAQLMLEEQMEKAKKNLVNEKETVREKKKIEKENSEEKIQIKTTFIKPLKKFEIKKKNNVFSLKKATTTTTSDTPNINNTKKNVENNISKTEFKSSDNTTSSSFSSKMSGINSIISRDLENNKRKAEGLDKNIKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYF9</accession>
    <name>A0AAD5TYF9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000812">
        <property type="protein sequence ID" value="KAJ3211813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYF9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="208"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="147"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3211813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="31162" checksum="4AEDBD56EA851555" modified="2024-05-29" version="1" fragment="single">MSIPIPARKLQLGIPIQEVPLPTPGFFLRECADLKLTGAEDVESNNPFESSFTTTNTNIKSEGSDAVSAHTGPEGSVAGSDTTIACIDNSELNHSPTIDYRPYFVSNNISHNTSNEYQMYYQNDSAPSTHNSLCEEPQKFLNEKNSLNLPLTSNSNSPNPSHSNNKVVPSNLNTNSCNDNVNNNSGKKRRASMKRKLTTESEEPENAEEKRRRMLERNREAAIKSREKKKIWFIELEKSYNDDLEKNRKLKQVILKQKENLTFLKNQILLHTNCDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYL2</accession>
    <name>A0AAD5TYL2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000471">
        <property type="protein sequence ID" value="KAJ3216563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYL2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF3">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="270"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="545" mass="63685" checksum="4F5FFCF04AC66D16" modified="2024-05-29" version="1">MSDAYMNATHILKVAGFSKPKRTKILEKEVLQGQHEKIQGGYGKYQGTWIPFDVSRKLARRYDVECILNPLFDFDPQKDKIGVKPVVVKQKKDDQVKVKKKSSNSISQNPAVSRNLTNDIGKKAQLEMQESVSKNHLEDTIKEHFHDLQSSKQNCVTPTRNKADFVSSNFSDDRTLVEQENFSDTTISNQQSPLLLDPTDEYMDLSKPLHSRGFLSPSVARMQVIENLPYSHRQKEVLLRIFKDRDYCSILNLLRTSSYQFDINLILDLEGNTSLHWASALAKVDLIKQLIYHGANKSMRNRFGVNPLIKSVQYGKNFELQTFDKTLELFKDVVFEVDFNKKSLLHHIILRFSHLEKNFTNTNNPANYADLNIELEEKICFYYFKVLIKFIKENFPYEITNEKKDATTDIKLEKKIHSRNKNFIMHFFELKDHNGNTCLNLASKYKLYFILEELLKFGCDKNSIDLKFYKNDLNLRMILNEEFPDNVYFEKDILPKDLHQNVDLFSKFANANKTSNWKDDNYHDKFQNVSNLIQYLENNREEGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYS2</accession>
    <name>A0AAD5TYS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005522</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000433">
        <property type="protein sequence ID" value="KAJ3217309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYS2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050367">
        <property type="entry name" value="APC_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770">
        <property type="entry name" value="AMINO ACID TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770:SF7">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="502"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3217309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="527" mass="57018" checksum="716895815C307CF0" modified="2024-05-29" version="1">MGKEKLEIDKEYLNKRKLCSPAATSFSIWAIIVGCVISGEFSGYNVGLAYGLGSMIVAHVIGTYNISCELGTAFPFASGCASYAAAAFGPVAACLIGYSYTLEMILINTQVTTFVGQIISDTTQTASQLKPLWWSLSIIFCGLINMKPKIFFRVITVFSTISVLILLVVLAISIPHLNFVKAWETILPDGSISTAFLPFGIAGVIKSIPYSLYLLICFEVLPCCAEETVDVGKNLHRGMGLGMLTLILCSWPTLILTAAFPTTTGISSAPSPMGAVLQAVFKSDSISLAAVGIPAIVTSQLAIFYAGTRFVYGLARGGYLPTKLALTTKADGAPYVSIIVNLVLILTLSLVISNVDATSRFAEIFLNAGTMFAFCAYIFEPIVFIKLRYSLPTLPRTFKSPLGVAGAVLNFSLALFAIVGQLIYVNLYRYLLATVACVFLLSVPFFFLVVKKNLQVSPEKIFISHQLKERYAEKINSINKESSRTNITKSDLELNAITQATSTQPQTPSSPWSLKKLPTTDNKSSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYT8</accession>
    <name>A0AAD5TYT8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000703">
        <property type="protein sequence ID" value="KAJ3213504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYT8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03114">
        <property type="entry name" value="MMAA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006958">
        <property type="entry name" value="PRK09435.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408:SF3">
        <property type="entry name" value="METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408">
        <property type="entry name" value="METHYLMALONYL-COA MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03308">
        <property type="entry name" value="MeaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="11"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="190"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="321"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="995" mass="115287" checksum="EF9D846660C90D14" modified="2024-05-29" version="1">MDASQAVIDKLRVALSLVETLKNENDAYKDNFEHLKANYDSINESYKALSEEYEISQREKVASEQQHVEQQQKLKNLLELKSQEFELVKSKVKTTKDLEIMKLKILEEFERGSKKTKSLLESEAEKFRSQFFKLKKECDFLKADRERYKNDVENHILDLKTSHQEELNILESKLISLKTSLDDIQDIEKLRSLQRENSDYDAKVVSLIQELEELRAEKETLKVNFEQQERLNQRRILDETANSKQIAADRDSLKSKANILEQEVKDWQIRNDRIVEENNHTLKEFQQLKLKLDEYSHKFNVETSDLKLQFLKEKGDFNNIINDLKKKLNEQKSAFKSATEQNADLKQRLANTEKEYVEKLRICREEEWQKQSRLECEKADLERSLSSQNQLCQEQLNQKEKIKSESNVEIQNLKKIIKKLESEFQFENEKIKEIKEKKESYEVELEFLKKNFFEVEKINANIKNELEIKSKNEGNLKEKITMLEATTKNLKEELSLAGVNFEQEFKSLEHNFERQIQVLVAERNNLFQTLENNKNEIETIVQGNIELADSLEKQQVVFKQKLNSLKIKAKDYKSETLKLRESLKNESLKSTENFNLRKKREMEFLTLLKSENLVSVVVAGVFAAVGGGIFMLGHFATSDPTIVLSKKKENPYPYVHLEQSKNIKLYAVNQKFEGKAREHFMDVESTRQDHKEEAQELLSMLIQENKKKKFSQQIKAPRFKSTFRIGLSGAPGVGKSSFIESFGVFLLSKDPSSSRTGGSILGDKTRMPELTVHPRAYVRPSPSRGTLGGVARNTNEAVILCEAAGYDIILIETVGVGQSETMVADMVDMFVLLVAPGAGDELQGLKKGIVELSDLILVNKADGLLEVPARMAQIEYTSALKFVTPTFPLWKPTVLSVSSQEKKGFDKIWEKMKKMHTILETSNELESKRGRQRKKWMWQRISDELLWRLRNDKNVKDTIDCLEDKTYKGDITPGRAGDIILDKFIFDQHNKEKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ12</accession>
    <name>A0AAD5TZ12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005617</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000446">
        <property type="protein sequence ID" value="KAJ3217061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ12"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="228" mass="25387" checksum="7CAB7872CED180C2" modified="2024-05-29" version="1">MTLILSKPSTTGLVVIADTRGSNPVTGEEIQSTSKLILISNGAIFGISGGVAYRKDGIFNITEDLASKLNSLQYFQLTERNIGRLLRIVTCALTSDVNRPGFVFCIWKNTKKYERIIFEVSTDGNLNVNINGSTSENQQHTAFGNTVVVNALASPLPNDSWSMLTNDEQMSMRTLRSSWHLQVDRGETVEYLKRCISLGNTISERLNFDWIGNNATTFWYDQTSGFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ24</accession>
    <name>A0AAD5TZ24_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000712">
        <property type="protein sequence ID" value="KAJ3213435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ24"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="264" mass="30511" checksum="AEA41A8B9D0B7749" modified="2024-05-29" version="1">MNPLRSEQKKRTNTNSKEGNMKEPTWSSFFSPIPQIPNTSSKSSRQSSAVASQLSHQLGRDKTGSNSKLQHNDHRRLQKPEDFEEATTIGRNKNDNGYESSLIITKLNSNNNLKIQNFNDTISKKLVKVDSVSSGSSKLFYKIGIHQYYPSEVSKLWTKLHQKPKLMVRNPDLNEEERRIHLGKLRFESENYRSLNGSHGLLLQFIGLLLFFSFLFIFLDAIAKEFSNYNGLIEIFSETQEVLMKNLNQFNIQDVKNELEKFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZD6</accession>
    <name>A0AAD5TZD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000387">
        <property type="protein sequence ID" value="KAJ3218297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZD6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041090">
        <property type="entry name" value="DUF5578"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34258">
        <property type="entry name" value="ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34258:SF1">
        <property type="entry name" value="ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17741">
        <property type="entry name" value="DUF5578"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="207" mass="23686" checksum="D0845E12E72E7AD1" modified="2024-05-29" version="1">MIYSEDNSNPYLPTLRNCYSKYGEMGISLPPIRNLKPNTELNLRILAQTKGKFTNSILRISRTWDQGNKKSREKILEEFITNNQNKTGPQLELELANGASLFLTRITTWLRLTDNRRCINGIRDFGPTTSERSNISYLKPKFITKYPKCHKAEALRLLISIANSGRTFKEFICESYGVKSVSDCLSRTKSDIVGDYCRNLLHQLGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZX7</accession>
    <name>A0AAD5TZX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000971">
        <property type="protein sequence ID" value="KAJ3208894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZX7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3208894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="21913" checksum="1F4433BA0C760096" modified="2024-05-29" version="1">MIRTATFHDVPFIVSNIYNNLVLTSKAIPEIKATTSTAKQQQWFPLDKKRDPRYPLTVFTVNDNIVGFAILEKFHPRSAYSITAELSIFEMQGYPTYQVTESLLKDVIIRAKILDFFSIIGKEKNKHFEFSLLMQKKFLFHHLVHVFDDDDKTLNIYKNHGFEIKGKLTKCLEKLGTPYNVHFLQLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U024</accession>
    <name>A0AAD5U024_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004908</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000362">
        <property type="protein sequence ID" value="KAJ3218832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U024"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058570">
        <property type="entry name" value="HROB_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15072">
        <property type="entry name" value="HROB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="2">
        <location>
            <begin position="73"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Homologous recombination OB-fold protein OB-fold" evidence="3">
        <location>
            <begin position="480"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="70685" checksum="98BDD50F487E0E43" modified="2024-05-29" version="1">MAEISQVPKLTEQVQELALVETIQDSVSEPTQNPALTEQMIQDFQSFIGTNHTVNIDKTGMNSLVHIVKNLSTNKQYALKHPLSSYSINSIKQEVTILKALENAKINFNQISVPTILQVANDNSLMNLLPGKNGFVVFEGLNNEDKLKMCREYGKCLKIIHSWKADEIKPLRADQNEKNLVLNNNSRDWLDVHLNFADVKLKDKIKRLEEKADLTAEEKQKNDKLIEENLQFFEEMKKILQDDSKWNESEMVLLHGDAMIQNFLFNEDLQATGALDWGDAGYGDKRFDLGPCLWSIQYLLKKADEGVTEETIREHKNAFLQAYGTQYQIEDVEQWLDLYDIYDFYQKTKRKYNFNETEVIPSGPSPLLEIPILPEPQTNYTDIPIPGPAGLLTDSIRNMEKGKKSITHSSSVNKKVKETCNYDDEEKERISKKIKISTQNKFQFKNFFENSMSKLDQSEINFIDINFILDKNNQNNFEKNKIANILLCIKDVKVYSDFDIGLVLVDCDGSEIDAFVNKEAIDLLQFNVGCILHLSDVSIFKPNELSLYLNITLRTIKAFFTSHGEKIELEIHQQKIKENVKNIASSISVLKTKEVENCDFLNADFDFGNMSDFSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U071</accession>
    <name>A0AAD5U071_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000521">
        <property type="protein sequence ID" value="KAJ3215761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U071"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051189">
        <property type="entry name" value="Splicing_assoc_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14195">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="286"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="333" mass="38235" checksum="65D02DCC012B01BE" modified="2024-05-29" version="1">MDEIKLKQVQVDEIIENVNIQALKSEDTIFQKDDSDSICLKDLNVYPITQIESSEHLINSKNDEALIEESCLKEKQDKTNLSKTQLRKVNKKNKKEKNREKKEFRAELIERSQRVQKTLIRAQAKGFASEFQIMENWLLSENETIKSFVADANLLETMIGPFGQKMRRLALKLCRRYNIVCKTHGHRKEKFLKLIKTNTTNIPTNNMILVQNLIQEFTNEKLELRDRRVERLEKQLNVFDEDGIPAIWYRKLEKAGKADPQFRGKVVHSSPHYENVVGETAKSISEACVGYKMLLKGGWTPGSGLGVDGNGNKDGIKVKIRGKRTGLGIEESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0E8</accession>
    <name>A0AAD5U0E8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Branchpoint-bridging protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">BBP1</name>
        <name evidence="16" type="ORF">HK099_008180</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the BBP/SF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000874">
        <property type="protein sequence ID" value="KAJ3210762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0E8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045131">
        <property type="term" value="F:pre-mRNA branch point binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02395">
        <property type="entry name" value="KH-I_BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032570">
        <property type="entry name" value="SF1-HH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047086">
        <property type="entry name" value="SF1-HH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF45">
        <property type="entry name" value="SPLICING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16275">
        <property type="entry name" value="SF1-HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9 13" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="13" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="15">
        <location>
            <begin position="270"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="15">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="394"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3210762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="435" mass="46887" checksum="AECE08DCEE552A6F" modified="2024-05-29" version="1">MNNPNNPNLVPLVPRKRANQGNNDNQLTEVKKRKSRWGDSEKKTIMPGLPTTIPTGLTSEQYDAYVMKVRIEEITCKLRTGDVLPVEIEGRPRSISPEPIYGPDGKRVNMRTQRYAKKLEDERHKLVEMASKKIPGFLPPSDYKKPTKTSERLYIPANDFPEINFIGLLIGPRGNTLKKLEADSGAKISIRGKGSVKEGKSGVTPGEDEELHCLIMADSEVKVKKAIAAVNKIIETAASVPEGQNELKRLQLRELASLNGTLRDEDALLCTNCGDAGHRSFDCPETSNVTINVVCKICGGAGHIASDCLEKNNPEALRAAEQRNLEMDTKYATLMNQIGEEQAATAPGSAAAPWASAGASAAPWATTSVGALPPGISFTQSQVPFNAMPGIPFPPPMPFGGGVPGFVPPPPPPSFDAAPQPLPPDEDVPPPPEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0M5</accession>
    <name>A0AAD5U0M5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF659 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000633">
        <property type="protein sequence ID" value="KAJ3214299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0M5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="59681" checksum="C91FF574D26F903A" modified="2024-05-29" version="1">MPSPPTLGEAVSSEPSIPSHSLKRKQLNSSAPFLWCLKPFSQETIRKYHELLAKAFIEGSKSFRLLDNPNFQKSQKLLASGRSITLLNRKSIVSRVIPTILQGYISEKEEYLSKNENFTLSVDGWKDVSGNIYACLLLVTKWCLKDNDCRIQEIISSNMALVNYFSESSYYAEVLKKWREENRFNHGLQTYSESRWYSFSKVFKSVEAHEEGFKHCKLLNDDANVNIPPLPPKILDILKDSGCYWTTNKDNSNIGDILPQFLIIVRQIDLVAVPLTLQNYKISVLSRIQKHAKKYLQPLYLVALFLCTKYRRIATSIKFSTWELKQVELGLFRLSLNQALPSTDNTMYLKEFALHIFHFVIIIEEWKVYVLQCVILKAKLEIEWAKVTIHLMLKFHQKRMERTQNSELDNTSELEMLEAFDNLLLEDECEEFEDGLNEGTRNDEENSETKDSRAVILQDALNEIFDFSFFAAKTKQFNIYIQGEKKKFSIGCFTNIINTEINSILSDFQNRNAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0N7</accession>
    <name>A0AAD5U0N7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004103</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000281">
        <property type="protein sequence ID" value="KAJ3220678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0N7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042227208" evidence="3">
        <location>
            <begin position="22"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="121" mass="13828" checksum="E6024F4571ECB6AA" modified="2024-05-29" version="1">MFKFNIFLLLNLLFSSALTQAVEQPAQNGLSREIIIVIIVLAIVLFFVTFFAFLVFLKKKRNANEPKGVEKEPKSVLSKKDSIREHRRELDEWKDELHNVTLNRNKSLQKSKAATGSVANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0R1</accession>
    <name>A0AAD5U0R1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CHS2_3</name>
        <name evidence="14" type="ORF">HK099_004230</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="JADGJW010000294">
        <property type="protein sequence ID" value="KAJ3220523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0R1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="620"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="651"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="752"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="13">
        <location>
            <begin position="132"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3220523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="795" mass="90972" checksum="9732B4107ED73228" modified="2024-05-29" version="1">MSSRQNNQRPNQLNYQRQNSNSNLRERSPNRTRNNSETSNEYSYQNNNRSYAPSTNSGRNDHYQNNVQQPQRTQPQQLPYNNQYDNRPYEHQPLVQQTYVPIPQSYHQQHPLMNPAPSQLSSSSNPQPRKKAIKHIQLTPQGNLVIDIPVPEKVLNQGKFRQGDEFTHMRYTAATCDPNDFARSGFSLRQQEYGRQTEIFIVVTMYNEDDFLFNKTMTAIMKNIAHLTTRSKSKVWGSGAWQKIVVCIVSDGRKKINPRVLNILGVMGVYQDGIMKNSVNGKDVQGHIFEYTTQMCVDTLNQVRGHDKDSVPVQLLFCLKENNQKKINSHRWFFNAFGPLLNPNVCILLDVGTKPTNASVYHLWKAFDRDPKVGGACGEIYAELGTGCSKLLNPLVAAQNFEYKISNILDKPLESVFGYISVLPGAFSAYRFKALQGRPLECYFKGESMHDGADIFAANMYLAEDRILCFELCTKKDEAWILKYVKSAKAETDVPDGVPEFISQRRRWLNGSFFAGVHSLTHWYYILRSNHSTLRKIRSVQEKNQPTDPFFGNRIIITEVLKEAYLLAIITIFVISLGNRPQDLTGNRTDINGNPDFSQTNISFGELTKTLFGRPAFRDLVVSTVATYGMYFICSFAYFEPFHMFTSMIQYLLLLPSFVNILNVYAFCNLHDISWGTKGDNTASDLGSVKGVIGKDGKETVEIDFPSDRKEINYNYETFLQGMQKPLEKTPQKRDAKTKQEDYFKNFRTKTLLAWIFSNAFLIVVLTNQTLINKFAAFAKITLDGDFNRKKNKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0U8</accession>
    <name>A0AAD5U0U8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000792">
        <property type="protein sequence ID" value="KAJ3212161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0U8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="199" mass="23503" checksum="E368049CD2BEC2AF" modified="2024-05-29" version="1">MSSYEIQRELNLKKNNQKLKELGLLDLKFNKPEIKPVQTKKKKNIRRRQFRVEEKLKEKRVSKRLSGAAPEFTFYEANLKLDNLSRLHQLEDDDKSKSVDEKENIFVVRKDDYFSPFITQKVVDLEEFNSCDEKIELKENGTLIEFPVQLESTNCKYVHPYPVGFKSKKLQFGDWWYQSVLEGDTGPVFEVSTYNLVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U157</accession>
    <name>A0AAD5U157_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000363">
        <property type="protein sequence ID" value="KAJ3218825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U157"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="115" mass="13052" checksum="C657B052C870E2CE" modified="2024-05-29" version="1" fragment="single">MKLINDLKEEKIAKSPELKKAQELKNKKSNLDEKYIIEPEDLERVELEKKKNRIEQNDGDAVLTSDELNLINKTVFKTVKVKALPEHCVAAALDMTRGDITEGKPVVGLRRAKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1C8</accession>
    <name>A0AAD5U1C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000392">
        <property type="protein sequence ID" value="KAJ3218169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1C8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="657" mass="75475" checksum="722D4D4F993F647C" modified="2024-05-29" version="1" fragment="single">MSKSNFNSSNVKSSSINSGSFSSARFPDPSKNTWSCLWQNCTAKFDTDIDTYNHLFTAHAKKGRQVCLWEANSKKKEPCNTTITHKGDFKHHAVVHFSHDFKPLTCPFCPKKIRNRQELHLHKKTHQIFNSKIDTNIPRTIDNTPTSSSPQSTLIQSTDSQVFASPAEFLSQLSLPDSLPQDTNNFEFRNNSGETSFSTYSNETEAAHQKLSSLLLPHQLLDNNQYTPFLQYNNPDTHYTNSNVINSPTNLFERLKFIDRSDVASSASDTFELTDLSNREAPLHQLHALNDRNVMCNNPVLASPIENQWTYDSLQPQSELLEPYNNPLPSMNYSDLMASAYSRTDNSLNFMSPSESNFFLTTTNALLISTLKEMDSPFSSGSSSSQSFQPRVNTTRRYSTSTLAQENNTDEEKQDEVIINNMVILPSYHVFDEKTSFSKIIIISEKNFNFFDKIISEELPSNSKEKLKNNYNTTFTDEYTPIAAQDLKKINIDTIHTLKNTKIPSKFFIVNREMRVSYNIGYNVCIFWNSVEMLSKQLKRPIPIEFRDKVIEIFQRDGIFGRLPPNFVLRLQGLFFRSSSDLAIIKKREMAKKSMSERLNYMITFLNNSIENTLIKEINFELDNLNQQGKFLEKNETFFPMFYENPPVKIILLLISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1N4</accession>
    <name>A0AAD5U1N4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Myotubularin phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003718</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000247">
        <property type="protein sequence ID" value="KAJ3221166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1N4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004438">
        <property type="term" value="F:phosphatidylinositol-3-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030564">
        <property type="entry name" value="Myotubularin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010569">
        <property type="entry name" value="Myotubularin-like_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807">
        <property type="entry name" value="MYOTUBULARIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807:SF128">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06602">
        <property type="entry name" value="Myotub-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51339">
        <property type="entry name" value="PPASE_MYOTUBULARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myotubularin phosphatase" evidence="3">
        <location>
            <begin position="54"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="1">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="207"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="269"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR630564-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR630564-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1249" mass="143409" checksum="B77D839293F3E4D4" modified="2024-05-29" version="1">MFYNENEQIELHQRLQNLINIESVQQLYAFSYAPEDVSITNEGLLSSTSSSFSGWDVYDPIKEFKRMNLPNNWRISNINKNYEFVPTYPEIIAVPSKISDTVLRHIGSFRSKGRIPALSYLHRTNNCSITRCSQPMVGLKQNRNIQDEKLVENIFSASQKVPKNNSHNFIIDARPLANAMGQMALGAGTENTDYYRGCKLFYSGIDNIHVVRDAQNKLIEALQTIVDGPVSKAQLDKSGWLKHIRHILTATLQIVQGVHLNDSSVLVHCSDGWDRTAQLSSLAQICLDPYFRTIEGFEVLIEKEWLSFGFKFSDRCGHLSRPTGGQSGENTASHPSFLSQLETGGNKVGKFFSLGLKSFMSQLNSSASDPELNLSVSSHKSASEFNQNKKKLETLEFTRQNSLTPKEISPIFTQFLDCLYQLFIQFPQEFEFNEQFLIDLNDNLYSGKFGTFLFNSEKERMQFTLGENNLKIQNLTKSFWEYVHVNKKNYLNQIFILEQEMKLKNFKGKNKETNSYLELNSDALNSEIGKAGSIDKIYNVLFPTTDNLKYWSGLFFRLDFNLDKCESDEDLTDFCKTDIIKNSTVSNKEKNLKLLIDENENEEMQKSLALGLKDQFGFVASGVLKGLNGLVTAMEYNLDDEDYQTSDPSKDLSTEFISDEVIGEETIIKKLEMFDLNSLIEDEYSSPASQFNSTSLKISANERMDSSKICASSISDPLHDTDDRFKLIDSTDALNELDEIQKKLQKKNEVNSLNDENNLIDAFPSPLNHYTLCDEDIMRQNSELQEKNNKGEINTRIEVNLINDNPWNTVNVGDTLNNSNLFKFLTKTLSVIEKHVVESHEDCRDFDEILMETPKLLLDLFSSNVKNRQFVTLDKKSVNLPTLPTEIITKIIKFAIADGNQNYLLEFALVNKRWSNLSRELLFHLIIIDNENIIPLIIGLESNNNYKKYNTNWFFPNTKKICLSDSLNYTSWLPFCELTAHLATSSSFFSNITSFESYISLPISSILTVTYNCSNLNSLLLNFIDFSEFNARDLNVKNLTVFKNLKNFRFYDVIGDALKFFNLAALENLEELNITLTSMKMAKIFSKYMEKMKVLKIVFTHEETSESYFLEILSFYEKILNIEELSLSGRFQERLIINCLIKRNLKHLKKILIWKKIKFKENFNLILRNFKNLAYIQADFDEELDDFILEEFCYSLNLIEFRGKFHSSNNLTSAAVNTLCLTLSNLKVFLGTKFNPEIASVFKKFKVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1W6</accession>
    <name>A0AAD5U1W6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ornithine cyclodeaminase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000314">
        <property type="protein sequence ID" value="KAJ3220134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1W6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="entry name" value="ornithine cyclodeaminase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001439">
        <property type="entry name" value="CryM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="29729" checksum="25947800DB5BFAE9" modified="2024-05-29" version="1">MPEGSLIKTPASTFLFDKVSGLLKGVINSNDLTTYRTAAGSALATALFSNPQSKVVVIFGTGPQALVHLKFMLFVRKTLEKVYIFTKRSINDLDVETLAKFKDIFQLVEFVFINSNNNAIGDLLQKADIICTCTNSKVPVFNGNLVNKGTHINAIGSYTLDTAELDDALMKKLTKVLVDSKVEAKKEAGELKSLLQQEKNNKETKNKIIFELVNINLENLENGSNNVNLWDNDNLTLFKSVGVPLQDLFIADFIYGKALEKELGTSINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Y3</accession>
    <name>A0AAD5U1Y3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Guanine nucleotide-binding protein subunit beta-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat EIPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000396">
        <property type="protein sequence ID" value="KAJ3218108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Y3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040323">
        <property type="entry name" value="EIPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14205:SF15">
        <property type="entry name" value="EARP AND GARP COMPLEX-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14205">
        <property type="entry name" value="WD-REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="2">
        <location>
            <begin position="269"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1068" mass="120814" checksum="11775D664A79DB0E" modified="2024-05-29" version="1">MTKSRSSHSQIGIRSPSENFNFQINPNDNWRKGCLPLTFKRQQKSVMHYSNLEIPDNQKNTTCIAALNAVPFLVVGSAAKSNNLFIIENLKKEPNQSQLMLKSAFTAPHSIYHMSLSGDKLATAGPQGCVQLFQIDSNEINQKGKGLDHLLECPLGESHLEHLQISPPGTHIKQVRIQHIEFSPNNFNDSTSSDSFLALQSKRLFIWDLEASKVVVDEFISNDMLTSATWSTFDPLIAATSNDKNLYVLDARLLGKSQSNKTGLVWKVDEAHLGSVTCAKFNPFIPYWLATSGESGDVKIWDLRFLRHPAARIDGHYESVNSLCWSNVRCDHISTASSDRSFKTFNLNPDLNSRKIFKNYSNFFFNLPDTGFRMEEYTSKEDLIVGSELVCESDFKSFNAPLLNICTSPTHSDSYYTISSIGELGCFTIKSDLLEKFAPHRYDSLHQHLEHEIETSVYLRDMTAAYSNVTSLSKLSRKKGRVISEFEIELIELCTAKPLIQPDSWTIAPFDSDSIRSGGFEMTERFRDDLRKFGYFLPPGFANLANFIKVKEEKEEAEFKLVVFRLNLLVDISKENFESLINAEGDIIAGMERDPTFLDAETLQLLLETIIINDYLKGLKMGIRLLEIIEDQPNKNFQDFFSTVYMLVYPTVFDQISVQPEIHMESSTDLKFKDTLLPLQQRSAHVKLQKLKHFIDGRRRRNLKLDESLNFISTKSNTLKNSEDVVPKNKINVNENNNLSFEFNKYKLENEQKVIIEKYLNDSKLALNMVRLELAMQKLLIKISPTVDEDIVKLMASIIGPKNNAKNSATLDLSPSNLKPFLNEITISSHVNRIFLDALLNLGRFDEYFSNALEFTIIFQNVDFMLLTFKHAEMIAVPKLKLFVDDVFKKASSRLVTAIHAGQKTALPPKDLPAMDAANPVLTDSLIFSIKCFKDGFVMLVKIGVGMASCVETRDSTKEKVVLNFVQKIISILNEHVNQLMSSLSKLLEMIEGLLGKIPTAIPRNSMLFVKDGISEAFKGWPKSFLKSNSKDPSYLERLKTVQPLQEAILIVMEKIAGFASKVADVQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U202</accession>
    <name>A0AAD5U202_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Alkaline phosphatase</fullName>
            <ecNumber evidence="2 11">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_003500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="JADGJW010000229">
        <property type="protein sequence ID" value="KAJ3221457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U202"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF5">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="25012" checksum="AB7AA60DF18DE825" modified="2024-05-29" version="1">MSALTGESTPLVSNQANFDADFDSEESSKISTSNKKNVIMMVSDGFGPASETMARNYYTYVNKLPFDYQLPLDTILVGSSRTRSSDSFVTDSAAGATAFSCGMKTYNAAIGVDPKKAPCGTVLESAHLMGYKTGLVVTSRITHATPASFVAHVVHRDMENEIADQIIGNTTIGRTADLLFGGGLCHFLPNSLPHSCRFDNRNLIQEAVARGWTVGSDLKSFDWLTPENAQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U244</accession>
    <name>A0AAD5U244_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000221">
        <property type="protein sequence ID" value="KAJ3221584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U244"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="516" mass="59885" checksum="181AE630AD94FE3B" modified="2024-05-29" version="1">MSIYCFWDNCNAQPFQSEVDCYNHIVHSHAVVGKQVCQWNMLLATSVIIYDRLSVPIWLNCSHAFRNRQDLRRHQLKFHSGNLVISMGEASKKAELVQNNQKISTIQNQHTSHHAVFEKSEKSEKSEKPEKIHNTIGSSVYRYPQSYPQPYYSVQEGYPNHHEYYSQHRQYKQLYYHWQPSPAYEIPYSEVGLNIKFFKSYCEVLRDSGINLPPNIFEVINTINNRGGRVPPMIESELQEALVYGEHPQITLAGLLTIYSTAAGVLIYEQFIKNTLAEAAEIFKILLENKVEQTTKQFTTESKTERTNVRSTQMSENVLCVIPTKKNKIFSNNRTSPQNIATAADAKKLPTTTPDEHADMTDIIDDPKLVEKDIFKTEKLAISTVKKHLVDFLKIFWKNVCECFSNEDQSEFIEIPNPNTSEDETMVMLRIMILHELEKLSNTIRRRFYFEAVKNLQENLYKLFNFETTGSFFRTSLMDFDKTSLCLYCKFGSNEKWVYTKPPINTENSFPSGFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U298</accession>
    <name>A0AAD5U298_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_004523</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000320">
        <property type="protein sequence ID" value="KAJ3219957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031559">
        <property type="entry name" value="SMG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF71">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15785">
        <property type="entry name" value="SMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="1252"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="12">
        <location>
            <begin position="1774"/>
            <end position="2113"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="13">
        <location>
            <begin position="3001"/>
            <end position="3033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="167"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2958"/>
            <end position="2980"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1629"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="2727"/>
            <end position="2754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="2959"/>
            <end position="2968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2969"/>
            <end position="2980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3219957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="3033" mass="348729" checksum="B1365B7BE9FCD974" modified="2024-05-29" version="1">MSMIESKRLPPQSIQLILYKFQTYMDGMPLEDSHYLPQILDVFNLTADLYPMILSNSFQDIVDRIVGWLVDPKISQAVSSAILDTFKKFQPFWCQHLQFCIALLTQLIKDTQYENFVSDCEPRGTVRSVLLFKPTIGNTDRFPLKGIPLWKCSFSILKAIFHSVFPNSRSDSERGSLHSSSPSRRQNSNNSRKQSFTRSQSSRHSTERSLSVSKLSKQKANATNLIKTLKFTDFQPEYVTQLQHLSMWLVEIISKVGKKYRNPEWISLGSQLVRFLSKYYRATVPANLSISMLNFLTLELNWHIENFNTESSVKDVVGSIEKIFQTVECWSPSCSPLILDFFLDPFDSILLSKARFIGLKDSNSLILKTCCKVVGGLSFTNDQVGHKKSINNLMKEIEFIFEKVFKLPFEKNANIQKKKFVDLSKLKREEMCSLAMFNINLLTECAKWGIPLEKDLDCGEHIYRFFEEIFQLVEPIENLDQFSSRVKDTIFISIYAVCRSLLEQNHASSGMLMEETIIEYCLQSHRQMLEKKKVLRFDYKILILNFFKEFFFNFYLQIKNSNIEPQFSRSLKKKISDCLNELILVLATWVDPYLRNFLANILLFVFENFSSLNVFSEYKLLSSHIQTLLDRTKDADENVVKTVLKILASLNHSATKLLLREYLKNGEEAVVENLIMRSNSYLSFKQKHFDAFMSSLGFVEILPLNSDEKYNLKIEKQGESFKMELGWLLGIFHACQSATSIKKNFDILTLQEQDLDNLIDRVEFSSDSLRFWGIWCSCQYLINNKLRSTFGDPRQTLEAIEYVLLVLIDTVSQKLPSKIEISDKQIFLLLNKLRNILHFINNLELLIQNAVLGAGLSVPQAPKMSMIFFSHNKGVCQDWLARIRRHLIFGGKLVGIENGFIIFHSLKFLNETLYLIKRGGLSDFDMLIENFHLVLFHMVVAYIELGDADCIVGLYSWLENSFHPILIQQDKKTYLSYHLGFLKVAVLLVTERVEQALTKLSSLISNSDVTVPNICLPLIAEMVAHYYKELNDYKSLENWTIHVEEKNFFSPEKFSAFKAPIHLWLKTFANFDNSGKSVNFDTFRQNLNFGLKEAILKLADENISKLSLFSDGRCEELSSDSIEILNCMLTANFLKLPDYFSYLFPLQVEMTLQTSLENTANATIQLDLLSNLVNLSTKLDGYSTGNLNRLYNVGGIVLKNVTGELEVEGRLLMDNFALNIAKFARKKQNLKLSQKLLGIVESISENSSILNIRKFVENGNYLFSTKKYEAALEIFTKAIDILEKSNFADQESTRALINKTCLKISQFYNINKKFDLKFLNFSPVENDTETLKPVEVITCKYLQKASKVCPLNSKPWYILANLYYRKGRKLVEDITSGKRTEILLLKQKIFNQPSNQIPESEISKLISSLFLKEIGEVDIVTNFSESLTSRLTVTFPHILPELVNEVSNTFKILEKEILYFYGLAVEGYLKFLNLFEIFDVTAANGDKAKDSKLSIATFRLIRILGKYGTRLKPHFENLDVIPSTLWEPVVMQLFARIDHNDEFAAKTVSKLILRIAESSPHLVVFPTVVGSLSKFSDAESISSYNNIFQLLYNKGHTKYVQEVKKMVIEFQRVTILWEEIWYHKLQAIRSDITKRIERFNLELKRLQNNASISEEIRKEVQKTDYFAILDPVLIHLRNVCKITIDLEPTTPHEIWFMETYGIKIRESILSLESTENFSIEISWTPFKEFLLELSNLVNKPRTIDIASVSPYLFNVNNSSIPLPGKSDNIVKIKAFSSLLTLATKTKPKKLSLLGNDGKEYSYLLKGLEDLHLDERIMQFISTVNTFLTTDKQFSKKKLSAATYSIIPFGDHFGMTQWINETNSFFSFYKSWQVIAKSTRVDAEGKSTEEIIRPAVQFSSKIAAAFQQQKLPKTLPRAKWPVDILKNVFLELEAETPPNLISTELRCSSPNPTVWLEKVNNFTKSNAVISMIGYVLGLGDRHLDNILMDSKTGNVIHIDFNICFEKGRKLRIAECVPFRLTQNMVKGFGLFGVEGTFRKSCENTLLAMRQNSEVLYTLLEAFISDPLIDWKNDIKEEQSRFEFEFNSELKLFSARLLEVSGFLTLNLESVIATLARFAEKCGVLATENAANENAVKRDNKLLFKKLEELRGWKSLHIQTYQHLKNPLNSQKPSQNFMLMPLQEYAGDALFSNTLNDINYLFNELNLTRVDNFNFIFENIHFYQSLINGNIDMLLKQDFSLKLIQSFDILRSGVKSANLFDFEKLFLSKKSDIDYFELHLQSIVNKKTSDLSDLANFLQACPAHLKDDEAQLRNQNIVTSLFSTNRQHNFVSATILNKLVEMGLLMSSIITTRADKIKISNRKIVVLRNVAVKVRGTSSSLPDTIHLSHVLILWLLQYLMMPDIASIFDDQKSFSGFYDYLNLSNGIFTFQLNFFNFIVPFQKKTQEMGESHMLMLITALDSIVKPNVHSDLFSIEHLVYVKKKLQLYESLKNRIYEERSEAKEIMVALDSIFLNIQELLFKISNQNPDMGNINLLIKYQIIEVKFKILKLCVAFSALNTSDPSGEWQLIVDFDDTTFDANKLFSSALRDLISCVKSFNTFCNNHLIMRPCVKKIKMLINSIPEIPYTEISNENFFEISNKVAASSTPLDENYKSFQLQLEDVVLNILQHSFLREGIIRMRQLELKMHQRVLGLMRYQHLHIAGESLLSDVNIQNYEVFKRLHSTLDLLANREALISQAETKLQCLRDNMESSNQNDAIKSLSVVVDKGIQVLNGEKEENPIISELFEYFKVKKDSLLEAIDAIELMFVKINLFIDHLGKLSKHLSKKDSIEIQEKLKLFTIIQNMKYMVLKLIPSTKVAFEALSNSSEKDPNCITLLLSCKFSHLEALSNKIRTTVHYILNAFKKGSLHDLTEENSLDFSDEQDYNFEDIFIKKNFLSEKSDVGMEKISNFEKEADILSDPQNSENSSVDQKEVRNSQAHERNVYASNMLKTVRSKLEGDVGRLNITDQVSLVINQATSVDNLSMMYEGWMAWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2P2</accession>
    <name>A0AAD5U2P2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Proteasome activator complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005287</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BLM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000402">
        <property type="protein sequence ID" value="KAJ3217969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016504">
        <property type="term" value="F:peptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032430">
        <property type="entry name" value="Blm10_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055455">
        <property type="entry name" value="HEAT_PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035309">
        <property type="entry name" value="PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021843">
        <property type="entry name" value="PSME4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170:SF3">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23096">
        <property type="entry name" value="HEAT_PSME4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16507">
        <property type="entry name" value="HEAT_PSME4_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11919">
        <property type="entry name" value="PSME4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Proteasome activator Blm10 middle HEAT repeats region" evidence="10">
        <location>
            <begin position="201"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4-like HEAT repeat-like" evidence="11">
        <location>
            <begin position="1121"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4 C-terminal" evidence="9">
        <location>
            <begin position="1705"/>
            <end position="1791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3217969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1791" mass="205656" checksum="DBA390C581084C40" modified="2024-05-29" version="1">MSQPKLRDRNLPGTLRGVSFVSSFTKSVKNYFSPESTKEILEEFLPQINITSRSNISIQSWLLFFLSTKSPPPPLERLEDCNAPPFYWVPTLFSLWSLVGNSRVYDPNFFNIFAKLASDQMTTPENVCWTEDQVKVIFTAGMKALKVPVSGANIGISHSFSGFASKSQAENLAIFVVSTIYPTPKVVGDPKHPNLNSLKHLREMIRSLETYFHPSNHGSWTKPLTFFIETLSSEMLKRIYFESDENKENNNHFSPILKLTKEIKKEFVLMLKGVAFFAMYSKDSSAVSSAQKTLKNLSWIEPTLIFPELLDNVYISLQTLTETHRTLSSIGVLSVCAQPLISRKNFPEGAIHIPQLLNLVLPGIDINDPRKTYATFDFLNSVFMFIPVHDLSSLSTTTSGDKDAMEVVKEGVEKLSLFEENYNLKMSTGFFEEFLVAFLERIFKLVENLPQQYGTSTTHSAESSILSMALYTSHSLFQQLSPTMLNLAIKKFERYVTENITPNATKSIARLVSNLHGLYPDFAIKTFIPLCAEKIKTEILNGASSTPSTSLNSSSKSSTYPYGFASLSDSTFHWFQAILYSVCTQCDGKIFLDNKIRSTLTEAISITLESKSFRGYKWGSRLLKEVIMSLGKVYLLDTASFDREQFKNKDFMAESHMHWGTPPNRPLNLQWHVPSNDEIIFAIELIDLYSKLCLKNLDSLIEISQQKKEFCNEYCKWLTILNGVIGGINAISAESPDEFDMKRDKMKNELPNETPIFFNVGLPLSGTDSNSKIVREIRMDIGKALIKIGNFFAEKRDSDVESIQTLTKCIKNYGILYGSSGVKPDLIADIEKGYVNQKNSARIFGKLSKHTNNKIAKNSYDLLPRKILAKRVFLQHYLRLQENIRKQYFRKQTCEIINDLVKVLLRFSINNSFAEVRKSSQSCLSLFCKYHETLIENVIFPTVLSSLKVRDDHTSDKMKGALYILQRSSLIHFGLRNWNNVLLFVKTLLTAQHEDKPSVQNRVRKLLSEYMSKYTEIVVKFTAEGFDKSFPLFDKDVNVLDNTFKSNLEEMTSSVNADFEKNTACYSELITFLISHLDNQYLHWYYRVATLTCLELCLQDNYAIPSRLVKSSIAGSLSDLKAVRKISTALLVRIMLYIKNRSLKGKYSPLLNIKGIRDFSLVIGQEDGKKEYTRKFALSTKTELYSREEWNNMIFVDDANFGWYCFPKSAKMYFPAENLEEPYPEPMSSEAIQELRESFSKDEFWEAFFKFASQEGEKEIEQLSMDLIKFYKSIFQLFQDSFIELIIPYIDKYIGAVLEKNYQRCCCEILCGIVLGTKNWSYEKLKKLWDWIIPFFQRALLNCSPEMLSYWEFSLTLICRKRDIRRLQPLIKLVLSSSALDTDSHSFFTEARKLSLVKVLISTLNWRFTDVCTDIFTTYMKHVQHPYQLVRNNLGSSLNACGQVWWHPSAQDFYEILRYNLFNRSGGFAKIPLELTQDLPGDVPLLLDDNRRNDMETLVRNLENWRNTSKSGDRRSTEYANAGKTVLIWFQNAINNQQTSGLYPYIKYLLPIIPQLQEFDDQDLQALAGVILKSYPHFPHTPRLLNQVIDDLIKLVMSTDCGWRAKVNILPMIQILFFFNLPNLNQASENLVMETMSELLNNAQVEVRNLAAVTLSGLIQCSQRNSIEKILKEFRNKLKTFPNIRKRRKTEKKEDDVKVTSELIVQKHSLILGLSSIVMAFPYTIPQWMPELLVELALSISDPSPISVTIKNMFSEFKRTHQDTWHNDVLLFNDDQLLVLNDLLISPSYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2W4</accession>
    <name>A0AAD5U2W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000382">
        <property type="protein sequence ID" value="KAJ3218396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2W4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039341">
        <property type="entry name" value="CFAP99"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34649">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34649:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="385"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="515"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="694" mass="80990" checksum="0D47D8C044E1FA5C" modified="2024-05-29" version="1">MNYKSLIQHAQNLLGNHSLFGLKDSLQNKSKISVFNEEDILKKYIDENQCFTNDEKLFLQKVFFGSIRYHSIITPTLETFYTITGSKQLRSKYNFFVVICYICLIHLETISFENFSSIIHSCPATDVYPFLKMIFDVDLLNGGLKEEWEKVLDHNFVKDNVIDVITGYIPDSQLLLKNLSLKTDEGYLIKKTKKKPTEPAPFELTVPHPRRFSTPNLKISNVFKAAPIPKSFYEGTGEKTAIENAKLENKKKSQTEQQNTKQFQVSKRITADKEKYAKEHERIRLQENKPIPKFKYQPPPKLINKPQNLTKQNIASILREDAIVRRKKKNDDNILNQALVNLTDLTEYQKKVDQDIEKDNFEMQLKVEKRHLEIQLLHEDSYVARKEKERENREIVKELIEEKNTLKSLTVQTKQEEEAIKKKIVEEVHEIKENITKARRNVMDENLKKASDLALETQALKAQALAEAQIERERKVELIHQIRMLEKQMPGISSHQKVVDLTETSGFGLLNEMCIVELQERLLLARVRHQEMEEKKREEILENKTKRLSMIAKKLQDIDTEREERKNQRKDKEEESKLALDAALSLKRAVLKEDPILKTLFEKLEAKRLARKSLSSTGVRSIKTFSNSKSNNETCESGIKSTNLQKSRNFNLQDFENEYLKRKENILKKRQTLIDKLNENGKQEKDQSLNEISC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U393</accession>
    <name>A0AAD5U393_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Alkaline phosphatase</fullName>
            <ecNumber evidence="2 11">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_001717</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="JADGJW010000151">
        <property type="protein sequence ID" value="KAJ3222961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U393"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF5">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="589"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8">
        <location>
            <position position="713"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="764"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="766"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="904"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="909"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="913"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="951"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="952"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="1057"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3222961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1127" mass="129110" checksum="694CDD9730134FA7" modified="2024-05-29" version="1">MYAKACEKFPKSQEKMINWYMSTIRSEDLNSQHQVAVKLNKTFSKIESKYYFWSVMTVFLQGKKNPKPNVYFTLAERMMQKAIEEKKVTDYQMIYLYISILLEQKKFEEVVKTLNSDLSLTLFKIEDDRLRLLELIYTKSGLFKESYDISLQMLRKSPDSWLSYQSMFESLFHLDSPDLNFTETFISEQQQQVQYPTRGPFLAMIDFFDRISKSDLKHDSTRSYLDLLISYVERVGDVYCCFDDLKPYLFSLSFEDSKTFLQKVEEFIKKDDQKTELKTRIKNNNILVNYLKFERFFFTKFTLENTNERETIVLKNIEKLFNLYQNTLKFGAKNLDKENHFGDDFLILIVFYLIDLFEKDKESLPHYLFQAISILEYGLKRSLYNIQFKLLLIRLYYKAGVFVRPITNMVVELDIKQTLLESIGWVYIEGLEYLASGKKLIEASKTFNGTLAIYVSSEKETPDMILEAFQYGTYSKIEEFMEFRANLKNSLQKFIYETLIFKTKLRRIVTFTDPDNEDEVKFGNSEGVKKQTYENVLENFNDFIESRVDNRDKNIFLNWSSNAESIATVLNNGEVIPDDKAGEQLIKFARSLREKLTGFELKLKKLRDKLNSAKEIKIRTELFEEFTPCFSHDLEFIGENVAKHYKLSWLLSLNGLIFEIEQLISILNPASETFARNYHNYVNGYPKTQELPLDTILIGSSRTNSDDSFITDSASGATAFSCGFKTYNAAIAVKSDLSPCGTVLESAKLNGYLTGLVATSRITHATPAAWSAHVSERDDENRIAQHQIGNYTLGRVTDLMIGGGSRHFQHKSVKGSKRTDDRDLLAEAAAIGWDVGTDKASFDALTSDSKLPLMRLITQSHLSYMIDRDPTKEPTLKEMSDKALNILKSSTEKEDAKGFFLMIEGSRIDHAAHSNDARTHFEEILAYQETIELAKKFVDENPGTILISVSDHETGGLSVALQEGIEFPIFEWLPEALTKQKASTAVVSSVFEKKNKELSGDAKYAYFKKEIKSIFNINPTDEEIAFISAAPDAQTIDNFLGTAVSKRAKLGWSTHGHSAVDVNLYAYGAGTNALVGSNENVELGTFVETYLNLDLEAVTKILVENVASLEIQPLITKRSVSHHHQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3A0</accession>
    <name>A0AAD5U3A0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Chorismate synthase</fullName>
            <ecNumber evidence="3 7">4.2.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004762</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="7">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="3 7"/>
    <dbReference type="EMBL" id="JADGJW010000346">
        <property type="protein sequence ID" value="KAJ3219244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3A0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04519">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="entry name" value="Chorismate synthase AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003793">
        <property type="entry name" value="PRK05382.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085:SF0">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="Chorismate synthase, AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="9">
        <location>
            <begin position="66"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="291"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3219244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1141" mass="126687" checksum="04773EBBE14E7D89" modified="2024-05-29" version="1">MGTHRSIQSLSDGKVPSIEKRIGEVLLKNDGDLLALICQTNFVGNTAANVSVGVLALLRKQQKGTTERFLKRLLSSRVEEYFIKGRDLSDIIRDNSMPTMLLNTYANYEGVTYLSQCISKPLYESMSLIEHCEIDPQKMPENSDENSLKLNIENLQKATLLFVDAILHEKEQMPNTLKGMCKFLNSVMTDTNSLLTSYDLHNVSRQQLANVLKPYGLHSSMSSDLNDDMHSPTKSICSLDLSPMRTTASNETSHTPPLSPTKSGLGIVTDDFDHTGSPKFRFFGIKKREKSKQSITESSSKVLQRPRKNSNASSKSRDSFSERNIKSPIKGRTISQSSISSENEKEVHSNFEFLRKKQQTQLTDILSAEQVEENVKITESSNENLTVVLPKQVIGDGSLLHSNYTGTSSNSSPHRNQFSTLTICDKVVGSFLFLRFFVPAITSPESYGFLEKRITSTGRRGLILIGKILTALCNDVEFGNKEPYMICMNQFLKNNKDRITVSANHSVKSSEEEVFRSTTSDNGEDSGFRQHYEHFAKNRLGQKIQGKSKSILSASLPSLHTASSPALQQPVCRTRSVEFNEAENFFNFLGKSIIKIEGDICEKFSCKGNCNEARSPQNCQNFNHQTSQFSIQNTHNHHHHHYHNVSTTLIENFLELKKLIEQSVYAEPDVKKKPESLLSKLGKMRIKTLFHQSGNQKDKKSLNSSSLDDLSFRNIKTVPGSIPNDKGSANSLDFFIFSFGKLFTITTFGESHCKAVGVILDGCPPGIPLSEEDIQISLNRRRPGQSDLTTPRNEADTVTIMSGCEKGFTLGTPIAMLVNNKDQKPHDYGEMDYYPRPSHADYTYLEKYSIKASSGGGRVSAAAVAEKYLKLTEGIEIVAFVCSVGEINMDPTTSYTSKDSENWLKNWKSWWHTLNTINRSEVDANEVRCPNQETAAKMRKRIVQAKEEHNSIGGTVCCVIRNVPTGLGEPAFDKIEAKLAHAMLSIPATKGFEIGSGFSGTLIPGNIHNDPFYKKSCGKLGTKTNFSGGIQGGITNGEDIYFKVSFKSVATIGQSQNTSTYFGDDGVLAAKGRHDPCVLPRAVPIVEAMSALVVMDALLIQKSRSSAIEALPKDIEIPHILRGTLKNLDNNLNTKKRKIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U414</accession>
    <name>A0AAD5U414_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000119">
        <property type="protein sequence ID" value="KAJ3223735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U414"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808:SF2">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="1">
        <location>
            <begin position="198"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="435" mass="50658" checksum="1233C22F4058A636" modified="2024-05-29" version="1">MSLSYLVNEELIRHCGIDKEGKNILTFYLCKLPDPTKNDYNEILQLAFQKLDFFVEEEYVLLIFCSASNYSPSLSWLVNAYNALGRKYKKNIQHLYVIHPSTIAHMFFSAIGNLISPKFYKKIIWVKNLKSLENFGFTLKDIFIPSSVLNYDNQLQWSEENPVSTSETIVNTFWSYFSPSLTTDNNKLESRTLIFGMKNFDEYCLKYGQPKVLEKCYEYIEKEGLDTEGLFRIAPLKSLTDMIKERYNEGEEKVFLSNVHVACSLIKNFYFELKEPIIRKSFYETVKKMEEFESKLEKIDYLKKEILQRNDDEFSRYKYENFKMLFKLLHKVYLKREKNLMNSNNLAIVLCPNFVRSEDVVEDMKLCSGGLVAKLAEPITLKSSGGFGVKEGIGQEGANSPKMNRIALIYLPSYGLMWFLTGTSINNALQHQKCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U416</accession>
    <name>A0AAD5U416_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000189">
        <property type="protein sequence ID" value="KAJ3222155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U416"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="159" mass="18065" checksum="0D72D99289EB3EE7" modified="2024-05-29" version="1">MHQRANKFPADLFLKDQLTQGLIQELVSVENKNLILSIFKDYAKLDKSDTYSLENLSEKFNKSWSKEILEQVGLETIDSFFSGCWFEFSRIGLILLTNALENSAFNPGELPFLDKFMACVNVCEQVLSSCSNKLSYTIVAPKSNEKMTDMSLFKGLPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U424</accession>
    <name>A0AAD5U424_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UV-stimulated scaffold protein A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000117">
        <property type="protein sequence ID" value="KAJ3223782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U424"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018610">
        <property type="entry name" value="UVSSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049431">
        <property type="entry name" value="UVSSA_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28670">
        <property type="entry name" value="UV-STIMULATED SCAFFOLD PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28670:SF1">
        <property type="entry name" value="UV-STIMULATED SCAFFOLD PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09740">
        <property type="entry name" value="DUF2043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UV-stimulated scaffold protein A C-terminal" evidence="3">
        <location>
            <begin position="334"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="493" mass="56510" checksum="0074B18CC2D17686" modified="2024-05-29" version="1">MVKFITNSLFCEEYTLETIKNWYEKFGNHYKQLAAGCNYIVNELKIKFLNNHGIHFQLSNEQFNYIKSLNLKKLNNIVGDIYTLELNIKENLNSMISCFNILLPNIITRENSDRASNSAANVSSIQETIKSFGMGSHFYSIEIDISNSDLGIKENAENKIIFDTLRSSIIVLTKHLEKTKEMITKLSRLDLEADSEKIKENTVKKLIYFKNMLEANKAKYLELNINPGNLIINDEYTDDDSNEEDHIFEEVQTEGACSSTQQPSTFLERKSTSFSNLKYDRKILPLNAKVKKRADDNQKKNNISSQKIEFVRKPVSDDKGKVVGDIIIKGDYNGSSDEEEYILNNNGFEFSHHGWNRVGENPTVSSKTLKNIVRKYIKVTTLPPSNIQPCKVKSSKTGKLCERKDLVTCPIHGPIIPRDDTGRALDNIIAEKEEAQDKQEGKKQLWEILANDIETQTESFAENSAKRRRLVSKREKPTARDRLEKKFKLADKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4H4</accession>
    <name>A0AAD5U4H4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Armadillo-like helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000251">
        <property type="protein sequence ID" value="KAJ3221108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4H4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013636">
        <property type="entry name" value="ARMH3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448">
        <property type="entry name" value="ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448:SF0">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08427">
        <property type="entry name" value="ARMH3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Armadillo-like helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="509" mass="60123" checksum="7FE5AE9EC9DE0A31" modified="2024-05-29" version="1">MSYWKEAGLSYLQYSNIAAKALRNVLKEAPKLEALKREEQYARIAKWTNGKAGEYINIEYFFQNKSTNSLKVEIDDDDGSKKDYTIATMSLILSYFFSKNLRLKKYLNCDKNELLASNNCFSFFKIDFGTLNIILEVASECVIDLTCDFEEGSKKASSYSEYALSFIWKWKPNTVKSEEEELLEKMNTRKKNLPKEVLPIIFTDLFDVLSNITSEEKRQLKLDFLSYFQLYVNYFKCLLKNREKFKLSSLNLNYLKLFSYNLKYVTSEENILYLDSEDLEDDSLQLILKVEVEIINYNLMNFQVDLFKKDEEETETEKVTTDQVEDIVKKSEISSSNSINDISEEKVKKKFKCDKKFDFLVLKCFLMLNYFISFGDRFLSDPHHYDRLFYEIIRNADALKNLYNYIVKKMEQNLKENVNDNASFFSEQLKNFDNLNLIFNYFLPKLNDFQQEDLNETNILDMLKENYTNLNLIIFEDEDDCWSLYCEDVTASELDIIKNFGPVLSEFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U532</accession>
    <name>A0AAD5U532_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MEP5_1</name>
        <name evidence="13" type="ORF">HK099_001364</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000138">
        <property type="protein sequence ID" value="KAJ3223229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U532"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041769016" description="Extracellular metalloproteinase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="452"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="740" mass="80362" checksum="C7559B71A1F6833D" modified="2024-05-29" version="1">MRTSSILTSLALTLAVSTAPADTGAAILNLPKYQQPASEFVINDAPPPSLIQPTPKSFEQKQQIATDYLVNITGTPKEKISLTSSVESGGKVLNFHFAPTEEGKIVDNANGNVIVDDNGNVLSYGLAWLPKGNAAPLSLIKTATIDSNTALKNVAAALNLAYDEKALTIEEVDGVKKISNFGEQVKGVIRISEKFYRTTTTLEKCFNVVLQLSTSDYLTIFVSQNTGKIIAANNWLTRDSFQAPKKLSKRETNYKYNVVGFPKADLTEKRNILINPADKTASPLGWYVKEMNKKLILFPFRHNVGNGDVGTTIGNNVKAQEFQNQNSPKRPTSNTFNFDYPVNEASEPKTYWEAATVNTFYVTNVVHDIAYKYGFDEKSGNFQTNNFNKGGKANDAIIANVQSSVLVNGQNTDNANFGTPPDGYEGEMNMYWFTTTTPKRDGDFDNNVIAHELMHGITNRLTGGPANSNCLDTDEAGGMGEGWSDVNAFVLTTKATDTRLTDRTTGSYVVNNAAGIRSYPYSTNTQTNPYTYKDVKALDEVHATGEIWATFLFEVYWNMIDKSGFSNNLLDNASGKGNTDFYQILINGLKLQPCNPTFLSARNAIVLADKNLGSKYECEIWKGFAKRGMGTGATSSFVNNHEVPAACSSTPPSTTTTKTTTTTTTKVTTTTTKTSTSTATTSPTTAACAHNKCVAGIALKANCDPCVKKICDQDSFCCSSSGSWDTLCIKAVKSVCKLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U593</accession>
    <name>A0AAD5U593_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Regulator of telomere elongation helicase 1 homolog</fullName>
            <ecNumber evidence="16">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">HK099_003183</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="16"/>
    <dbReference type="EMBL" id="JADGJW010000212">
        <property type="protein sequence ID" value="KAJ3221731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U593"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904430">
        <property type="term" value="P:negative regulation of t-circle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010569">
        <property type="term" value="P:regulation of double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090657">
        <property type="term" value="P:telomeric loop disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000431">
        <property type="entry name" value="Regulator of telomere elongation helicase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012923">
        <property type="entry name" value="Csm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057498">
        <property type="entry name" value="Rtel1_ARCH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF34">
        <property type="entry name" value="REGULATOR OF TELOMERE ELONGATION HELICASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23109">
        <property type="entry name" value="ARCH_RTEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07962">
        <property type="entry name" value="Swi3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="21">
        <location>
            <begin position="13"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1051"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="264"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1057"/>
            <end position="1075"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00073810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3221731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1119" mass="127599" checksum="F47AC621550F2388" modified="2024-05-29" version="1">MISEIELPLSHKANISIKFPYRPYDLQINFMTKVIQCIENGGNALLESPTGTGKTLCLLCSALGWQENYKKLNPGWPKKKIYFASRTHSQLSQVIKELKFSGYNPIISVLGSREQTCINDEVKYSATGTALSSICENTVRKKNCMYYENSIGSNLQKDGKNKIMDIEELVKFGKEEKKCPYFLSRCNTDTSDLIFLPYNYIIDTISRKSQKIYVRDSILIFDEGHNLEVTCGDASSFELTTEDLNRALREISHCIQFAKEKCFRKELIESFENLKNAVEKFKLEILKINLKTTKTEFEALFIHQLFENIGVLPASSQELKLISNEIYKLLINEKLINYGNVGVKVLQEALNTVFKYPPISNHQECDKKNEFFSRSAASFWKAHRVHIISSTVLIKRQNSYTHQEVRTLSFWCFNSGVALTELMNEGARSIVVASGTLSPLESTALELGVTFDYRLENPHVINTSKQLFIGVLETSPAGVRLDSSFYNRENPAYLQQLGRSILNVSRISPGGLLVFFSSYEVMNNCIRNWEKLWVGNINSLWSSIDGVKKIFKEPVIKKDFGKVINDYYAAIKKGEGACFFAVCRGKASEGIDFSDSKARTVIICGVPYPASKDPKVLLKKKYLDKQKEINFKSLSGDEWYLQQASKAVNQAIGRVIRHRDDYGAILLFDASKQLLKLKTHDFVPLFLGFSSNIRHLPVWNRQSCKVYDKYNDIHSGISAFFKDKKEVVKVEENCESEPIPVQKKELKVNPAQNYTEGILQPISSIFSEKKLRKIEKKKNIAENKNHSNSKQQQINKSFVVKKKRVNVSKSVDTKLALLIQAKNVLSKADFEKLKDAFNVYSVKKQKDCLLNQVKDLLLNKENPTEYAALYEGSPSEINNNGLLKNKVNGTVQYKPSNSNLNQNTHSGETSVLQSNFEERTLNLNVDKNFEQLGTSKKIRTVRILSEKDLLAESGLPFLYEKGRKIKFKGKGYEVEDLAKLLNFYQMWMHNIDSGISFELATQKIERLCKKGSMKKYLNDIVIKERQRKSGIENKLTRNDNDDKIEANLEIIPEPSRPIQNQEIPTPEESPQQQNDTSDETVARIKANRAKALEKLAANKRLRENKEMFASDSDDDIPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5D8</accession>
    <name>A0AAD5U5D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004102</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000281">
        <property type="protein sequence ID" value="KAJ3220677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="794"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="667"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="745"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="667"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="745"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1382" mass="160375" checksum="24BB1109C204CD03" modified="2024-05-29" version="1">MAKTKEMINEEWLPENVKKLKNASKKPAAYTISSKDKSVIDSLDKSRNLLESRSDSKYEIETEEKFDEETPIQVIPSKLLRDTHKQPIFNFEIRENALELRYQIEFDETLNLLPLNVNLRKLQQKLFKYFLVKHYVSSEKLKLIIKFEIIEDKLAEKDDMLLKELNFYRTQYLKDKRLLNIPSHRSDFFFHEAFTQAQYLQRGKSATPYQRLNIKFQTELLLDSLNINSPHWSNHELVRDESFDIKNSVSSQNKICRKRFNDMEYLIYHFGQRFIDEDKKESSSIEERNLEPIYTVTSSNNFVIVTIFQKNLKSNQFKAIYKHKTLLVTFVDFTLKLLPIKLESLDFNINYDQSFVEINGENIAIHLYKTVGASKDPKNFVLKIKDQALREIKKEANANGISYEEPKKKKSKKKKSKKAVEKTNGTAAIPIKKEEVLLTVGMDDTNTAMCKTLGMDIHKDESQVNLNSYILVDQNSGLVETMRNTHTDQTNENEKNCNYINEEVGLLKSENSQKANPVEPLTYERCEYPEFGCNVNSELTKSLYNSCLNENSSSNKSKKRKKNKKCAKNDVEESSIKNLANSKNIVVGDVSFERNNNLNSSEFEHVSPQSTFVPKKIKKVIHQGEVPSLQEDEVVETSNNLVPTESMECGNTDSIVLKENKVKSSSKEFNSKIKCEDSRTSDNESFSHRPEVESPTSINSETQKKKRKKTNKKSVVENRHHLALKQKSNGTKVLTASCALDTENNADTLNENNNCSDDELHHNSPASLNAEVNHESTSVSGAEETKEDIVLFNVNEGFQSENSDIPIARKEFMSEDIDEKNFFLQEEGDECNESKSVVRNKVISGRCGLLNSGTVSNANPCNAVVKYSNLFDATMQHDSQEFLNWLLDNLHEDVNLIKTKPYVEMDDYDGSIKDEEVAKIFWDAHVKRNDSLIVDHFYGQYKSKMTCTVCRQISIKFDPFMNLTIEVPNLTVDTEVFFVRSDNSTTIKIRLNIDYDFSIRRVIQKLSANTGFPANEILFAVHKCGEYFFDYDTQKFLDSSWTQISLVSNYEFFFYHFIPNRAYIQLLHCVKNVEDSSRLIVDKNSFMSISAGTYSMSELKNVIHKNLEKHLITLEEPYMLEEILQKTMHFIDENDNIVTDDQFDLESGCITSFKVLWSSQIFDYESFITPKLIKKFNDTPSPTFVFLSDCIKKHLEVEIVDEYYCSKCKKHQKGEKKLDFWKLPSSLIIHLKRFFQFSHDSNWIKREVSVDFDLEGVSFEEFCLNKKEYQKYDLLSISNHYDTSHCKVGEKWCQFDDDEITEISNSDVINFRSRNGVHNLPFRYHTEEILFSTQCTNICTENLNVFFKFYVYLTPPLSEIMVLKKSLTKDRQDPFPFCEFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5N0</accession>
    <name>A0AAD5U5N0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5N0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="349" mass="40681" checksum="19A1CD7148FBF16B" modified="2024-05-29" version="1">MNHEGSDNIKRRSHSLDPENGLTRKLSDFQLGTAYLKFKFRNIFNKTEEAQYNTVTWKQLNSKPVSENWIASPPDLKQIPNTETTYSPLSEITVEEFIPVKKLVHENERSSNSFPIYETEVLLQKEENSFQPSFQPVLDSQYIPSASQVAGNIEISSNPAPDNSVLNYPFAEEQHDIPFPKKNLNSEIDIVSETLKRFNTHNNPEPNDNTSLMHEELENSNFKSILKHLSVFEEVQISPESLRRLELKKNLKLRKKLRFNEVTDIFETYSNFEYPRLSMPEKSFDTSDKEELQDLLEEEKEEKLTKYDSFKVKNVNSFTYDFSDSSAKKEKVGLISTWKNIFSRKKFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5X1</accession>
    <name>A0AAD5U5X1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HTA1_4</name>
        <name evidence="14" type="ORF">HK099_006594</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5X1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000008">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042171844" description="Histone H2A" evidence="12">
        <location>
            <begin position="26"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="54"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="234" mass="25643" checksum="A882D668B1FFB7C7" modified="2024-05-29" version="1">MQPTLSLFFVLLTNFLSIHVSKIAATIQNHRENVKILGTSPEQIDIAENRYKFSRLVDKIGVDQPLWKELTSFEEAKAFCEKVSFPVLVRPSYMLSGAAMNSGAVAEVEKSKSGSSSRSSRAGLQFPVGRIHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGNVTIAQGGVLPNIHQVLLPKKTDKEGGKKGEASQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6G7</accession>
    <name>A0AAD5U6G7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000045">
        <property type="protein sequence ID" value="KAJ3226062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6G7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF730">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="107"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="153"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="193"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="333"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="423" mass="47641" checksum="16EED30ECA502A0D" modified="2024-05-29" version="1">MISEKEVVMDDLNSLEINTTDFSANIGTDEGDFFQSDRDLELSKLKADKKKNFQESGNPIKLNSKILKFELVLDLITYSPPTKAYTAESGFVSKKIDLITGKTLRIFRGHTGPVTSVAIIYNSDGDDEFIITGSWDKTARKWCTKTGKTVKIFSGHTDFVKSVKCVKNFLLTASSDKSIIQWDINTGKELQVFKGHTRGVEDLVVDDSSSQFFYSCSSDTTIKKWSMITGKVVMELNGHLTSVYNLHLSDGMLWSTSADKFAKRWDLEAMVCDTNLEHPDFVKFIKTCGDYAITGSRDEEVRVWDINVTKFLNLFFKVVFISKKKSEKCVYTFQGHFDEVSCIQILSNNKFVSGSLDGTLRTWSLSGNINNLLLHNYLFSDISACKSVSKESEKKEFNTKAKKNSSTAMTAEEEAELNELLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U701</accession>
    <name>A0AAD5U701_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription elongation factor SPT6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Chromatin elongation factor SPT6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SPT6</name>
        <name evidence="15" type="ORF">HK099_007391</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Histone H3-H4 chaperone that plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression. Essential for viability.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SPT6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000071">
        <property type="protein sequence ID" value="KAJ3225104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09918">
        <property type="entry name" value="SH2_Nterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2740:FF:000002">
        <property type="entry name" value="Transcription elongation factor Spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2740">
        <property type="entry name" value="Spt6, Death-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.850">
        <property type="entry name" value="Spt6, helix-hairpin-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049540">
        <property type="entry name" value="Spt6-like_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028083">
        <property type="entry name" value="Spt6_acidic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042066">
        <property type="entry name" value="Spt6_death-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032706">
        <property type="entry name" value="Spt6_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028088">
        <property type="entry name" value="Spt6_HTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035420">
        <property type="entry name" value="Spt6_SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035019">
        <property type="entry name" value="Spt6_SH2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028231">
        <property type="entry name" value="Spt6_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055179">
        <property type="entry name" value="Tex-like_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017072">
        <property type="entry name" value="TF_Spt6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145:SF6">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14635">
        <property type="entry name" value="HHH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14641">
        <property type="entry name" value="HTH_44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14633">
        <property type="entry name" value="SH2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14632">
        <property type="entry name" value="SPT6_acidic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21710">
        <property type="entry name" value="Spt6_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22706">
        <property type="entry name" value="Tex_central_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14639">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158832">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="15" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="S1 motif" evidence="14">
        <location>
            <begin position="1118"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="13">
        <location>
            <begin position="1245"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1423"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1426"/>
            <end position="1436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00093389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3225104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1709" mass="197079" checksum="D1A281AE98A3C625" modified="2024-05-29" version="1">MSDIEEEIQRKSDDSGDEGEDVNKDNDNKVIFDSSEEDEDDEGELSESDLKFIADDDDEDNRKRRKKKQKRRSSENEEESEKEGDVENDDDESVEKKRRHKKKRRIMEEEDDLDDEDLELIGENTGIEQIEKKKFKRLKKKSDREETRESTSFNGSERNNHSNDLNNIFDDDEMDAGDNRGTEFDNDDDLHSSRRDVRSQKELFNMSEDDDDLDDFVIDDEEESGDEETKRQRREERKKIKMKERKLVKNMGMNLGISDEAWRDIEEIFGDGSDYSWAMNVGMDNLRIDEPINFDDADPYLHETKKDIKLSDLYEPSEIKSKMLTDADEAIRLRDIPERFQLVGDTMEKDEINDKDIQEEAEYITRIIYREFPGGALPDAKVVEKSVKTVLKLFKTHYEVPFIHTQRKDHINEVDWNQNGKVYEILDRSRLWRVYDLMLQFEAIKKKRTLVSEMILKLFTTMEDTSFNVDSKDIVLNFKQYLRSATTLEEINDVYVSLQSKFGDAVNDLELKKSEDSNSGKKIFKRPARRKIHEDAKRCNLSGLANLYGINTNDFISALCLKSVDLHIPVDPEQDPLVVAENFKHRAYPTPILALEGARHIIAHEISSDPKMRSYVRKIFDSDSDITIVPTNKGVAEIGPNHPYYAFKYLKAKPNYKFKDEQFLQILKAEEEGFVQVEVKISPQFVDECVKCITNDSFNQIARHWNDERKQVVDLVLNQFLFPGIVKGLKEKMAQKASDYVIESCIKNLMQDIDMTGHDIDNRRNRENIMAVSWGDGEKTSPTFAVVVDRFGKFVDYIKLDRMQDSRMEVKEGDLETLQNFHRQHKVDLVLVSGWSTNTKSRLFMEMERAFGNSVEMIDDQVARIIMNSKSSLSEFNSMDVDRDHVSMVAYCVSLCRRGLDPTMEFASLMNSNDDYNGVDINAAAAHKHKAHTLKFICGLGPRKAQGILNIIHRKLSGRIESRAQLIEKGCCATSIFMNCSSFIRIRSIHFQGRRDAQILDLLDDTRIHPEDYDLARKMAADSIEVDEDDDAVADDPSAHVQQMIDNQEEYKLDELDIRNFAEELMTSLNEPKYLCLLEIKAELKEFYRERRRRHCPPTDEKIFYMLTGETETSLHLGLVTACRITRVLEKMVKVAFGSGSGIEGVIFVNNLVDNGRVGQTCEDHGFKEDDVIKCKVIKIDFNMMQVELTCRPSEVENNLFESSIRKDEYFSEEAEKNDIKDREALTRKVQAKKIRKVNHPDFYNIDYRKAEEMMKDKPVGFYILRPSTKGINHLSVTWKVLDGICQHVDIVDFEENGVKGFMVNDQKFSELDELLIHYIEPMSRNVREITENIKFQKNKNLEETKAYIREQTKLIKRTVYGLIPVENRPGKFYFVYQHYGGNPIPKYEPISVRSEGFFFREKLFKRLEDLIVGFKKMEIEKAKNSQKSSTQQSRSGNERRAVDRASNPAGGYQSTLDRSLVAEDSLLDPPAIIVLQVKSFAQRIANGTGADCIIPDLYNGKSTLDQEEAAHLMNNLNWDDALQNLSGLVGDLRKKNEKRKIGSVGKVPHIFKISNFYKIGFCMGGALSLALASKLAATKNPLNATISFYGVPPMEKYNLASIPAKTPCNAYFGELDTNKGLSDLETAKKLSKLWKVDIKGLEYRKHGYYTEIANVFVLKNKGHAFMSDEPEYISKCKELGFAGPGDKELQGKVWKQVFEFFQHHLKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U739</accession>
    <name>A0AAD5U739_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">asparaginase</fullName>
            <ecNumber evidence="1">3.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003973</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U739"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006528">
        <property type="term" value="P:asparagine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08963">
        <property type="entry name" value="L-asparaginase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.40:FF:000001">
        <property type="entry name" value="L-asparaginase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="entry name" value="L-asparaginase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020827">
        <property type="entry name" value="Asparaginase/glutaminase_AS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041725">
        <property type="entry name" value="L-asparaginase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707:SF28">
        <property type="entry name" value="60 KDA LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500176">
        <property type="entry name" value="L_ASNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00057">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00144">
        <property type="entry name" value="ASN_GLN_ASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-asparaginase N-terminal" evidence="6">
        <location>
            <begin position="35"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase/glutaminase C-terminal" evidence="7">
        <location>
            <begin position="299"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="561"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="661"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3226861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="774" mass="85206" checksum="E8AD9E26BE665C5E" modified="2024-05-29" version="1">MDEENDHFYLNEEPLLSRYKSFEDIGEMVQTITSRVLIIYTGGTIGMKNTTNKGYAPAANYLPKVLSDMPMFHDKTYFCYEEENLTDLNSNLVNIPLNGDYIDNEIYSNLRKHAVINGTPVGRIRRPALVTPFSLYGKRTRYSILEDWSKIATDIEVNYQLFDAFIVLHGTDTMSYTASALSFMFEDLGKTVILTGSQVPLAEIRNDAVDNLLGALTIAGHFVIPEVGLFFSHRLYRGNRSSKVDAMNFHAFDSPNLKPLVTVGIDIDVDWPNVVIAIIVLRPTAISRFKAHKSLIGSVAALRLFPGITEATIKAFLAPPIKGVVLQSYGAGNAPNNRPDLLKALKEASDRGVVIVNCSQCIRAMVTGVYATGKALFDCGVVSGSDMTPECALTKLSYLLGKGYSAEECRQLMSMNIRGELTVFQKKKRFTYQFSTQNLITSVLNMLDDGSGTRIETLKKPATNLFQDTVKPNNSKILNDSLFSSSTPVSSPNIPVNNGKVSFDDTLSSMTANAVKDSKLPGIERTLVPMMLCYAARVGDVDGLQSVLSEFGTLVNVADYDGRTPLHVACSEGNLSTVEFLLNHGANIHIRDRYGHSPLWDGLKSRNSSIVKLLKKCGAHFSEELAGQVTSSLISYACAGDLEMVEAFVNCGADLNRTGIDNRTALHLAASEGKTEVVKFIVNLSITLKRNDKINEDNGDKMKFLPDILGGVKLERSLSVSTTNSIDILSKQCIWINLEPLDKFNRTPLNNAIENEFLDCAEIIRNGIKTLENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U744</accession>
    <name>A0AAD5U744_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M20 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003751</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000025">
        <property type="protein sequence ID" value="KAJ3226959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U744"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05672">
        <property type="entry name" value="M20_ACY1L2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000004">
        <property type="entry name" value="Peptidase M20 domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017144">
        <property type="entry name" value="Xaa-Arg_dipeptidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF0">
        <property type="entry name" value="XAA-ARG DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037226">
        <property type="entry name" value="Amidohydrolase_ACY1L2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="184"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="408" mass="45391" checksum="10E89A6323FCB4AD" modified="2024-05-29" version="1">MSAIDVQIFDFVKRKALEVSSELREISLAIHCNPEIGFEEKFAHNLLTSFLEKKGFDVTRSACGMETAFIAKYSPENIIKEKEKIITTGFLSEYDALPKIGHACGHNLICIAGIGSALIFKSVIDELGITNLQIKLFGSPAEEGEGGKIIFIENGAFKGIDFALMAHPGSLDIVYANFLALQHFTCEYFGKAAHASASPWNGTNALDAQILAYQNIACLRQQVLPYQRIHGIINYGGAAPNIIPDYTKSSWMCRSPTQVEVRILKDRLDKCFEASSNATGCKVELNTTSFFYEVKRNDSITSVFKKWQEKQGVLYTSREFQESVSRGSTDMGNVSYVVPSIHPVFSIVDEDDPKPFPDIHTEPFREVAKSLKAHSKTLTCIVSLVMSALEISFDKELLKKVKKEFLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7E4</accession>
    <name>A0AAD5U7E4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002644</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7E4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042015400" evidence="7">
        <location>
            <begin position="17"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="24"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="139"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="385" mass="38861" checksum="67A3A63FB6BAC13D" modified="2024-05-29" version="1">MKFLTTSSFLVLLGSAVTLNVENQYIVKLKAQNSFSSGGNNGLDTHLTWLDEVLAKQPKALVASDSNKVLHKYGNLGKWFTGYAVKASADVLEEIKKNNQVEYVEPDGVSTTLATTWGLDRVDQRALPLNGAFNPVGNGQGITVYVIDTGITAGHPQFEGRASEGAFFVESNAKDGNGHGTHCAGSIASKDYGVAKKARVVGVKVLSASGSGSNSGVIAGINWVASNATPGKSVASLSLGGGKSSAVDAAVNAAAAKNIPFAVAAGNSGGVDACNASPAGASGAYTVAASDKNDAKASFTDLGPCVDIVAPGVGITSTWLNNGVNTISGTSMATPHVAGGFAALLSQQSFSSASAAYSALTAKSTPGKITGLPSNTVNKLLYVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7I9</accession>
    <name>A0AAD5U7I9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000014">
        <property type="protein sequence ID" value="KAJ3227569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7I9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05162">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053063">
        <property type="entry name" value="PWWP_domain_containing_PDP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42851">
        <property type="entry name" value="ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42851:SF13">
        <property type="entry name" value="OS08G0477800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="33"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="477" mass="53891" checksum="E657AF5E4DA286D7" modified="2024-05-29" version="1">MTEEENNSLKNSQENDFKIGDLTWAKIKVYFTYFELLNFPSQGYPWWPGMIVSEDSLSSEVLKSKPKKDSICVHFFGSRDYGWFSQDEVKPLASHWDDFSNKNKTHQFLRALKEAKTPECLFEPPAPPEIKKRKSTNNEDGSKKKARKSVAQDETEDDEALESEHSSKKSKKKKPGNDSATKDRRRRSFVKKSDNEEEKESTEFYLSLEDTDALDRVMKMRIKLQKFLQLKEERDERSFEKAHECLLQVEMLPTTKLGKVLKKIPGIDFSEEADKYHIKARVNTILAKWKNCLEDSATAPAANDIDMAGNDARKSDIPDFVMKDESALSPKKENASSGNNIVEVSNKARSASPQKEMTSPTQKQRSISPAKEKVGSPKKDRSASPNKLKESSPMKQQGPAAEGDIDKSVENNKSPLRDVSPAKEVASKLKDRSTSPVKEKASSPTNDKIISPTREKPLSPIKLRGDSPLKSSKEIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8P4</accession>
    <name>A0AAD5U8P4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8P4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="32"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3228493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="583" mass="65961" checksum="AEE29F19CA99B06E" modified="2024-05-29" version="1">MLIKTFLGPALRTIYKRFFKESGSAVEGFLDAVKSVPNKTALIFTLTGEIWTYKKLNEDTNKLSNFLIENNLVESKQVVSIFLPNSPEFIKSWLGLWKLGQTCSFINTNLKGNSLLHALKVSNSRYIVTDENLLEEVLIIKENLMDLKVVVLSTAVNGEEKFGLLSKDVLLFNENMSDAIIEPHNFRKNVLSTDVALLIFTSGTTGLPKPATLTHEKFRILSNVPRFFGLGKNDRIYTALPLYHTAGATLGFGNSIYNCSTIIIAPKFSASKFFYDCKRFDATAFQYIGELARYLLTTPESTNDKNHSVRIAFGNGLRKDIWLNFKSRFNIMEIGEFYGSTEGNASMHNHQVGNDGIGAVGRAGPIASIVFCSVLIEYDQENDIHPRNAKGFCKQVPYGVEGELIGKIQTWHPTRNFAESRFRTGDLLRKERDQRYYFVDRVGDTFRWKGENVSTGEILGAISKFDIKIQEAVVYGVEVPYMDGKAGAVALKVDEDFKLNELYGFFKSEGLPSYAIPIWIRILKKVELTGTFKPIKHQLQVEGIDLKNFDKDDKIFWVKPGSNEYVEFTKSDYQDIIEKKVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U949</accession>
    <name>A0AAD5U949_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000090">
        <property type="protein sequence ID" value="KAJ3224538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U949"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1124" mass="129174" checksum="536D4D38ABCA9F69" modified="2024-05-29" version="1">MNKNLQLPPIYSNNLSNTQSTDSIDHNYLNINSTCLMYSTSKLNHHHPSLNGSNFRQFKIKPVSPTLPKINFPENSISNRNLIFDCNTVLTKSHFQDNDFDVDKKKIQIKNSHNLNNISKITPINTVDLININIADTKKNRRLGWWDGKEDNIENEKLKVTELLRMNNSSNCDDLSDNSINEPEDEKETSFSYGEAMTNENAVVVNFDNIVTECSNSETQAQPKDKSEIDEYSQLETKLKNNSTSETSEQITDENGIQCNIIKESNVEIKEFENKTILYNQVTNSEKNSSEKEEIIFAVAAPAAEKDFQCDNLEIQVKPPTIPKHPNKNSYRRPNSIEQSSSHNSARIQDCDSKTSTLKFDQVEKEKVFEEELNSKFGENYYFFNKMDLFHNEKYSNFKSLFEYIVLEKFENALDLVNQVYNKFRLIVNKEEDKQKIKKMHLAFEDLKYIITKFWLMNTIQSEEKRYSCSESILENSIKPIVEQEILRNYKVVDEQSGEKVLGSRGEWFRRDYSMLKALLLSYTESLPISSDNIYSTLNLNSDMNNFWFTFLNFSISNYNKKNNHQTQQDSCPLYAIALESYFPLPINGLVDKVDQIKSQQEILPNNFGKVAEYQKKVVKEFKIENLNSDKNTEFGGTNNYRCEEKSVAYTSSRKSKSRTSKLDNQQQILNDDFQSISSSVFSPTAEVEKLMPPPSKIVETSDFAISTVCGPVLTHIRALDVIGIPETGEIIAATAGGEDRSDKKISIWNCREGKLLRQLDNLNFKPIIILNFIKNKKNDSNFLVSIDMEFDLKIFDWKNNEILKVFKKIHTRIIYQSLIFGGGGDDLGPNSRIATCSADQTIKIFDFKEDKPAFQSVHANEPFTSFVVCGGNSNDVSGQTLVASLSYCLRVYKMRTLSLMHVIQMKQLKHNHPTYDNYILISCDNQLRLYDLSSETTLRTFSARTLTPGVRIEGKFSPCGTFVYSNSWDKRSFFYQKAQNNTQLQKNKKKNLHSNNANNNNENNFPEFSSKGVFIWKVQNSKLEKPEMKAMEEGCSRFSLKNQFSVSKSCIENNGLSDNDEDNIVNDGHEYGKILNLPVTCCKWILMENKSRFVNSSQNSNVNLSYRKVLVLTTLDRTIRTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9L1</accession>
    <name>A0AAD5U9L1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000067">
        <property type="protein sequence ID" value="KAJ3225221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9L1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="28481" checksum="52F4F442674C0E4C" modified="2024-05-29" version="1">MSADWEEITVEDVKNYNQENEISHSNDVVLTKCLVTKDMFLNEPLLFDDDDRLELANNYLFEDNLENSTNFIIGRFKTTLKRDNELKKYNYNWLKSKKKIIFNNFSKRLNSIAFSEVNKKKKTICKEGNAGCYFDRNNTEVLKYSSIDTTGDDEYFNISYRKQIHENQNRSYYNENNYQNLHNNTENENKRQKFSKQSNYSTGYYCEVEFDEVFSNCNEEGFYELFKEKFILSFSVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA03</accession>
    <name>A0AAD5UA03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP synthase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ATP5A1</name>
        <name evidence="16" type="ORF">HK099_005963</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA03"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18116">
        <property type="entry name" value="ATP-synt_F1_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1-ATPase_alpha_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.150.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002432">
        <property type="entry name" value="ATP synthase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="entry name" value="ATP synthase alpha/beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a_nt-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009884">
        <property type="entry name" value="PRK13343.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="15">
        <location>
            <begin position="57"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="13">
        <location>
            <begin position="179"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="409"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3225907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="539" mass="58506" checksum="767014FCFEE873F2" modified="2024-05-29" version="1">MFRQVTGLTLRSALSPLNRSFSVAAVARAAAKPGTAEVSSILEERILGSSSSIDIHETGRVLSIGDGIARVYGLRNVQAEEMVEFSSGLKGMALNLEADNVGIVVFGNDRLIKEGDIVKRTGAIVDVPTGEGLLGRVVDALGEPIDGKGPLQNVTRKRVQMKAPGIIPRQSVNEPMQTGIKCIDSMVPIGRGQRELIIGDRQTGKTAVALDTIINQKKWNSGTDEAKKLYCVYVAIGQKRSTVAQFVQTLEEQDALKYSCVVAATASDSAPLQFLAPYSGAAIGEYFRDNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNKTFGAGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFFKGVRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDASTQFLLNRGSRLTELLKQAQYKPLSVEHMVVIIYSGVKGYLDKIPVHKVTVFEAGLIPYVQANAPEIFDAIKKDNEIKPEIDAKIKKVLEDFVKQFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSH6</accession>
    <name>A0AAD5XSH6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001309">
        <property type="protein sequence ID" value="KAJ3204362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSH6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="71" mass="8602" checksum="28AE3E468A364439" modified="2024-05-29" version="1" fragment="single">MTKVTFQLCQDQIKHWKQEGFLLLTDFLTEDEKLIFLNAAKEISNWPEKKSSYMHYYEKKNGERILCRTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSS4</accession>
    <name>A0AAD5XSS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001073">
        <property type="protein sequence ID" value="KAJ3207186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050818">
        <property type="entry name" value="KCNH_animal-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217:SF435">
        <property type="entry name" value="POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10217">
        <property type="entry name" value="VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="6">
        <location>
            <begin position="86"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3207186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="495" mass="57523" checksum="1ABBFA71604E712C" modified="2024-05-29" version="1">MKNPTHGLPSCLVEEKDVETYRVIEDKDTSGWYNLIDPQSPFMRKWDNTTMILLLFTACVAPFEVAIPFRDTKTGMLVNEKGAIIAAYLKSWFFIDFVSIFPFEFIGWLARLLKLLRVLRASRKLQRFRVNSRISYPKIQLYTFMTILVFLIHWLACGFRLASDKNDPIIDRPGWVDRFATYNHVNVTTLTISEVYMLALYWSCSTVTLIGTSYPPLQADNIREWVFVLFANLCSYAIIIYFISNLTDLNVHANKDQREHELKIDKYLGMFYNFNLNPAIKYKVHEYLTDQNNLKAESEYQGLIKALPQQWSGIINLEIFLPFLARIPYLEPFLDKEPGLIIDLCKNIEMVAIPPNSFLFSGGLNGIYLIEKGIVAIDGTVYVRGDIIGKSCLRFKIKKNEGRALTNVVAQYIPKDTLETMLGKHKKMRYYSRRWTAWEILRKYLIAYKRLYLLAAKRGSLMSPPMISKRGNMDDVDFDDIDLAVMEHMEEYGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUA8</accession>
    <name>A0AAD5XUA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002224">
        <property type="protein sequence ID" value="KAJ3198940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUA8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="97" mass="10933" checksum="9F66314C0CF056C4" modified="2024-05-29" version="1" fragment="single">MQLDDGVTAQQQALYYFQGELVQQRLTTTFTSKNNGDYTVRDAFPLETTVWSSCKSKANLNINSQIRVAGPNNKQGLITIDSVDAKVTQIYSLQWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV44</accession>
    <name>A0AAD5XV44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000398">
        <property type="protein sequence ID" value="KAJ3218064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV44"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="26522" checksum="F650B39213B807CB" modified="2024-05-29" version="1">MKESLDREQKSSIKSEKNFKKKIKKKNQKVDVKSATDPPTLTYNEYFTTVETKEPTIIPTFTLPKEQTSLLSNDNTSISPLSTSHLIAILIPTLIILFFFFLLLLILFIYIKIIKKKQKKRQANSSSNLNLKKKPQDSFFTKTPKMFNVKEKKVFALLQPLGSTSGYSLTPSLSDSAAGTYDHRFSLERIIRKENPFTTETITEEKETEMVRNVDFIEILGSNDEVVNATQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVB3</accession>
    <name>A0AAD5XVB3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002069">
        <property type="protein sequence ID" value="KAJ3199640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVB3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="377" mass="43179" checksum="E8A64999B91AEC32" modified="2024-05-29" version="1" fragment="single">RSAVEYNETLHKRTPCSSGSPSHQWDLSINLRYPCTSPERKTTSPPSSCILTSNNVNALNSPYLIDLWGEGYTSSGGLVTGCKRCYNINKEIQLVSPSASNAGCYIPNRIPVSNYYNWDDTYFGQYIPNKSVRFFNQEGSPAKDYTANQVIQALRPGGLFFTFGMAESELQIIERAFRNPRWTLPIDRMISELKVHTGRPAVFFTFNWNLNNLKSVKCARSKQSLWNIYYQSREQSWETCETAYLPPIYHIDYNHDVVPLYCVKNILSGMDAFFMASDDNCPITKYHGRQYYKWTYDAKDTEGSCTNGLITQRVYGQYTWEESVYGSDGREHTMQQGDWSNSGCDVSIDFWKSLQVRYLNGVTYSVPDVQILFAQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVD9</accession>
    <name>A0AAD5XVD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ANKRD39</name>
        <name evidence="4" type="ORF">HK099_004777</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000349">
        <property type="protein sequence ID" value="KAJ3219179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVD9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="54"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3219179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="213" mass="24647" checksum="1378E097DBF56DD5" modified="2024-05-29" version="1">MNLCNNHNCETKFHSTNQSIDEVDFLRSIQYYAQIGDLQKLQTKVHLVNSVDSYGYTALHYAARSGHIDCCLFLLKNAADMNFQTSNLKTTALHRCCNGDKLNVFKLLLEYKADYKLKTVDSKNFLHVLFENNSTSILNFIFCNEFHTIIKKKLNDPQCLVDTLNLGNNVKFSMMELKTLLNEADVKNKKPLDYYNKQTSFIDMQLLEIFMNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVG1</accession>
    <name>A0AAD5XVG1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000340">
        <property type="protein sequence ID" value="KAJ3219405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVG1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47457:SF1">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47457">
        <property type="entry name" value="OS05G0345500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="643"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="725" mass="83228" checksum="5F70497F9A903B95" modified="2024-05-29" version="1">MFEPHIKKTSENLLSARRLSNNEAIERNNIKYLNLYGSPASVLTSTDVVTIEEKLIEVASSHHFLNLLKTGEFSDFTVIGPDNKTYKLHKFILSRSDFFNTLFRNENFVESKKQLVKLNFEDKENVFFWIVQWMYGEASKIEATKIFSVLVLSDLLQIQELVKIILNHITENLSNDVTDLLEIFKKICQHRLENNQTYFNPDGSFDSLNETNTLDKLDIYEKVYKKILKNLAKNFNLINEDYDLGFIHPTVLTELLDHNDLLAKNEYQVFKILANYCGRDRADYIKNIVSTCGCEENEQRQSTMQVTQQQQLQPQNLAQITKKKVSNFFKKESSKFINTEPLTQLHTSSNQQQYINSTYQCSQTLNDLNTLASLLHQEECIFRQDLNPTLVNVFFERIFFENMTENELKEASFNQIVPKEFVIRGLMEMVRKLKGQSSNVPLKTNSRRNSIITKKGGEFQYARNWDENGVLFYLGTQDSAHYRNPCTSGLVKVSITPTLKEGVPANILSRQPRCTYTKRSDIGKSCQLVIDLVSWELAVTHYTLRHGYSQDTAESLQSWTFSGSNDGGKTWRVISVHYNDDNLGGEYGTHTWPVGCEEWYSVFKIETMSQSGAILVISGIEFYGDLKPKSLLSMAIHTKRRSIPESEEQECENVSKSKKETITTSNNSTSKVNEVSNSLPISSNETVNDDSLHTFHPNFENFSVRKRSMSVPGNSTLKMDLSSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVH1</accession>
    <name>A0AAD5XVH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tafazzin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_004663</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine</text>
            <dbReference type="Rhea" id="RHEA:33731"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64743"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:33732"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:33733"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the taffazin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000336">
        <property type="protein sequence ID" value="KAJ3219521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVH1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047184">
        <property type="term" value="F:1-acylglycerophosphocholine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035965">
        <property type="term" value="P:cardiolipin acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000872">
        <property type="entry name" value="Tafazzin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497:SF0">
        <property type="entry name" value="TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497">
        <property type="entry name" value="TAZ PROTEIN TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00979">
        <property type="entry name" value="TAFAZZIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="13">
        <location>
            <begin position="50"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3219521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="244" mass="28148" checksum="429ACDEE82D69184" modified="2024-05-29" version="1">MQVSNFSRLSVTAFACIFTRVIGKLTRTSIETYNKEKFLNLILNRNDRGLITVSNHTATVDDAVVFSVLPLSVLLSTPSIFRWSLGAKEICFTNSLYNWFFSSGQILPIERGAGIFQDTMDRSIEKLNKKEWIHIFSEGRVNQSSEMLRFKWGISRLIMESKIPPLIIPFYHTGIDKLLPLKSYIPRMNNEVKIAFGNPIDSKILLKKVEGLNEKEARIFIANYLREKTIELQVNFKKYNFNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVR6</accession>
    <name>A0AAD5XVR6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001605">
        <property type="protein sequence ID" value="KAJ3202213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="226" mass="26051" checksum="055890E054E2702D" modified="2024-05-29" version="1" fragment="single">CVPETQVCLIQHRIRTLRDGRKVALAEKVHEFLDWAQRYFEISICSLGDQPYVDMVVQVLDPSRNMIRGLTYSARGEYLHIQQTPYPKKPPKDLAAIYAFYNVDDVDKPSISPIIIDDNISMWPQCQQDNIIVVRESKPSPVWNVNLIPIQALLQSIHGEFFKQVDNWELLDSESKLISRPVVVDCYKDLLRKDLSIRIASNAGVFFDEEKEVELLFDSNGIPYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWC0</accession>
    <name>A0AAD5XWC0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002122">
        <property type="protein sequence ID" value="KAJ3199404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWC0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="283" mass="32404" checksum="B7A7B28435D83A5B" modified="2024-05-29" version="1" fragment="single">MLDLKFYLDDVDVKIDQACDEVQTIISQHLSDFIDKIEIVADDLEWPGIFYALQYAKDVRTLVYSHAEKLVEHCQQIALNISLTTVAEVEKLSINCCEEDLKPEKEALNLILDEQNKEKNLFLLPEFNEFLDNSDKIGIVKEFGPATIIFTTGLLGFKGVFKNFFSSVGLNAPKTLFAGLAIAGTGMFLFALSDIRRVLLKKVVQKIRIHLNDLNYTSFNSEKILKVTRRSLTSCLYDFNTKFDRALKINQFNLAKREEKKNLVKSREIFFKNLENSSINLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWL4</accession>
    <name>A0AAD5XWL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002692</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor Fz/Smo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000191">
        <property type="protein sequence ID" value="KAJ3222113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000539">
        <property type="entry name" value="Frizzled/Smoothened_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053247">
        <property type="entry name" value="GPCR_GPR1/git3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01534">
        <property type="entry name" value="Frizzled"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042012522" description="G-protein coupled receptors family 2 profile 2 domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="9">
        <location>
            <begin position="96"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="560" mass="63872" checksum="0BBD81B5C71B50F8" modified="2024-05-29" version="1">MQKLSLLVFILIQLILSIYSFNTDQIHHVKIKSIVSNDIEKREFLPLKCPKNLIFVDFNTTLNSDTSSCLTLGQGYCCLPCPIMNFYYPSNQITAILSGITVVRLFSIFAGILVIVVYVLLPQKRIYPRNIILFLTIAMLLWQVVFVFTIGDEKYSTFCSNDFEMAQQSNVKCAFQSSIAVFASIACCFWAFFLVLNAHLQAVWSSEFVGKHPVIIHVISWGIPAIFSVAALASNSVAYNFGTVCSLKSNSLYYYLFIPTLCVVLPTCALHFLTTLSLMFKSNFIRRIFCFGSKNNGDVSLEESNRYRVIGIGFVQWRILLLTFGVVSSLSGYWTYQKIVVDKIMTLFKIGNSNDSANLDHLALFSRCDPSYVVSFKNNKEQCEKEYASFVPPLYLVVIFELLFSVAGFLSFLIVFVGTPTLKEFFTWIKEKKDKKSEEPILFKVEDIRLEKIRTNSLVTMREKSCKRNYDDFPFNITESNESILETATTKSEVCKENWLYGILQDNLTNQHSSTIHFWFRVVIHPDSTRATSLTDDFVTVNVKPVLPFANTPHCWINST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWT7</accession>
    <name>A0AAD5XWT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000172">
        <property type="protein sequence ID" value="KAJ3222519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWT7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="355" mass="40785" checksum="27F3CDBEED10B4D0" modified="2024-05-29" version="1">MLATLNKKKRGGKIFYSPRRRRQYATEILELQAEFLKKGNKNESQKKSRIKLPTEVLHLIFSAPVFNSTFALARFIIVITKNKALASFVQILDFSPSHPFRNMNLNYIKEKTVSPVYNPIRNTVSIRLHEPQCANMFSDFSLPNSRNLNVLQLQNIITENRNPVIGNNDIDSNSENFASSLDSSVSSANAGSTYRERFRSLQNHQNQNRRTFSHLETTPTSDLIIYSSFLMKLGQCCRNLKILNLANCSSIKDDRFIPELNEYASSLEYELQCDFSSTLISSVDAMQSLIKHCEYLIFLDFSNCNWVTDDLVSKICKSDLRYLKAISLKDCKLLSSKFDNLFFEKDNDSLLFQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX52</accession>
    <name>A0AAD5XX52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000513">
        <property type="protein sequence ID" value="KAJ3215886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX52"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47562:SF2">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="323" mass="37374" checksum="F5C248ACDFB77C56" modified="2024-05-29" version="1">MEILSKINFFDDKFSNETFFFVNVIESINLKIEHEVQEISNQRLNSKKFSKISPLKSLLFIIADSIKDLITEIFSAQDPQIQEVSTRDQLLYKDMFDCTAAILILNFCLPKFKPVQKNLNLKKSSFLFLLEDIRTKLDKIVQEKIYPDELRSKCTRLCCFNLICGEKKCRFNLNFVESGVDNLITECKFYLRFGFLPEVTAIVCLFPTDIHNANLSLNGDDTLKRVKELEGNGKEVLMIFGKQDDHIPEKGRSIIYHSLKSIDCSWVEVNARHAFTRDEFSKGRYDPAMKDIALSLTQELFHRRLILGLPSLKDILPQPQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXF6</accession>
    <name>A0AAD5XXF6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CAT4</name>
        <name evidence="12" type="ORF">HK099_007625</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000756">
        <property type="protein sequence ID" value="KAJ3212971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXF6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000012">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="11">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3212971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="16523" checksum="12B4FA06F473381E" modified="2024-05-29" version="1">MDFTKGYEVCLEEIVNDAVFDEDHDEMVVVRDIDIFSLCEHHLVPFFGKVHIAYIPDGKVIGLSKLARIAEVFSRRLSVQERLTKQIALAVEETLKPLGVAVVIEASHMCMVMRGVGKVGASTVTSCMIGAFRNDPKTRDEFLRLIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY50</accession>
    <name>A0AAD5XY50_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Triosephosphate isomerase</fullName>
            <ecNumber evidence="6 9">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TPI1</name>
        <name evidence="10" type="ORF">HK099_008014</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="6 9"/>
    <dbReference type="EMBL" id="JADGJW010000838">
        <property type="protein sequence ID" value="KAJ3211376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY50"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000025">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3211376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="237" mass="25935" checksum="F196F8C213807B6E" modified="2024-05-29" version="1">MNGNTKLVESLSTLLNDGKWAENTEVVVAPPAPYLALARSKFRSDIGVSAQNISEKDSGAFTGEISHLMLKDLGLVWTILGHSERREIYKESDELIALKTSVALKNGLKVIFCCGEKLEEREAGKTLEVVFRQLKALKSAISETSWGNVVIAYEPVWAIGTGKVATPQQAQDVHHDIRKWLSDNVSSKVAEETRILYGGSVNAGNCKTLQEEKDIDGFLVGGASLKEEFLQICLARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY99</accession>
    <name>A0AAD5XY99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alginate lyase 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004357</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000303">
        <property type="protein sequence ID" value="KAJ3220434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY99"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042281501" description="Alginate lyase 2 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase 2" evidence="3">
        <location>
            <begin position="178"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="424" mass="45834" checksum="A92EB72DBAED1614" modified="2024-05-29" version="1">MKFTSIIVSAFIAILLISFVNAVPFPKSDNSDKKEVSKTSKSTPTPALGSNKSDDEKKNKEDKKSKPTSTKASKETKTSKSSPSITEVTKTSKTEKTKEPKTKESKTEKTKTPKATKTKKPKDDAPAATGTDTSELDNSNGSSGGDSSVPTEDPTGTTGDVSQTSAPQEDSPKSNSKIDLSYWLLQVPNPKDQRGESGGFKHWVYPPKLDGTSVVKSPTKGYEIFKKTSNGLVLTMDISDEIGAAGGSAPRSELREYQKGSSNAQAAWDYRTGTHSMKASITINKVASGCSTNNIKGGGIIVGQVKTNSGEEIISLRYYSDYDTKVKDGKPFMKRLQLIFSNGGSKLIALPQDENYKLGTKIDIEFKFVDGKFTFYFNGKANGNLPFDSNDAYFKMGAYAQNTSGCKTTVNEMTIHSLSVTHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYG9</accession>
    <name>A0AAD5XYG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic nucleotide-binding domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CNBD2_3</name>
        <name evidence="2" type="ORF">HK099_007459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000723">
        <property type="protein sequence ID" value="KAJ3213313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYG9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011:SF28">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="361"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="486"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="684" mass="79166" checksum="E3E84A04CE803AC2" modified="2024-05-29" version="1">MLKFAEGIPLDDDVDNTATIKVSRQRFTFSAPPKVAKKNFSTILEKPLLERPKTAAMLSAKEKELLTENINLQKVKVDAQQIFLKLQEIRNEKKETASEKIREINAAMKGNGLVKEETDWKTESNHDEVEDETFNRQTLLDVVNTYTYRNKKPDLNLYLKRAYSAPIKRTPVKNEKLKLINRPKSAPFPINSDAFMKHWIIKQGGKLRAQKYTLNEKKENCHFEFLPEIPDLFREGPPTLADWKNIKKFEEKIWNPDAFSLKQYFHNYALQNEDKKKGIHIHITKTNEDHTKLGANTFKSFSKDSVTSNTSSNVKLSAENEEINLKKLEKLHVLQILKKACFSRTESELDKLGKYLKKFNAFQKISEFILQQLCSVMILNTFDAGRAIFRQGEMGAAWYIILTGTVSVQITKTGRIEDSIVVSKLHEGDGFGELSLINEAPRAATITSDFRTELIRVEKHDYIRIMKFNHEKELKEKIYFLLRVPIFGEWTEASVKAIAQFATWRRYKIGEFILKEGQQITELFFIRKGNCDVFRRIIYLGRKDTVLIGKHYPDEYFGEERIIMDDDSVRSACTIVASKSKPAKGAKKKKKLENGTEVVEVLVFPIFNIKDKLKTFLVPSKFSGIETSDVIELKINKIKKNEWRKVKAEQIGKFIKESKKDPNITIKKLNLEVAFKKNHPLWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYN9</accession>
    <name>A0AAD5XYN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003722</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000248">
        <property type="protein sequence ID" value="KAJ3221151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYN9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="527"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="608" mass="69609" checksum="4E76C170931E7BE3" modified="2024-05-29" version="1">MNLDSLNPDSNVQYFRNYKITKVIGSGAFGKVKLGKHVESGEKVALKYISNEIIRANVNYILLKREILVLKLLSHPHIAKFITSAREDREYVIVMEFVEGKDLFEYINTSSTRKDKLGLDENIARHFFRQLLSAVDYIHRNFIVHRDLKPENILIDNFMNLKIIDFGFANLFNPRYELNTVCGSTGYLPPEMIKGEGYIGPEVDIWCLGIILYAMLTGKPPFPTKDKGFRKTLSANFQVPSFVSQVTGYKNQPPRSYFPIREHIRNASMLDRVVLEKMKEYELNEFINISKICDPIPNPSSSLYHLIKEKLLRSLIQKKERLPPSTNAIHTSDRNDQCIQDKLQLQQMEVNSYIEREQIEAEFFSDIPEQKSRALQNQNELNEIVKSKRTENNTNMVRERRKTYDLGINLMKSKTKTRSSELESNESNTQHLKVPREGRRASADLGNLIKMYYSSKKNIDVEADSIQQSTEINDEEVAAEINKDIKNNSLLQINDNPVKIRPRKKSELGQMLKRLSMTDKTIVLEKPMVERPTEAEDSETSSAGSDLLGSTSFGTLQASNNGLNSANTSLDRKFNLPVADNRIKRGVKIESNNVFRRVFGLKGKGKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ29</accession>
    <name>A0AAD5XZ29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003519</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ29"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="587"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="426"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="479"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="683" mass="76362" checksum="F8E067F2AC316422" modified="2024-05-29" version="1">MFQVLIFQIGFAKFRSRSDAINAIDTLCGKKIDQDRGFYMKAEIAKKNLLITKRSISHDLTSPHNSSSIVASFNVRNASSTTSLMLNNAASTPTNNFKLRSSSVSSSSSTSPSPAFNQSHSHLPAHIPVYTELVLNTGNCESTAHNSQKSKKFSKPFDDVVHSSSITFSSNDSEVADIHCTELETNSTHLEHYKNDGYFQLPKDLLNGLDKLESSADSLDILTSNQTTSSTSSNFNSDIVSIDYSETSLNDNSLLSKKKSLDYNTDADVSSTTIHSTLPYTIIDDLASRFDAKMSVTDYNILKNSSIAAEVARNKSQASLPLWDSYCKNNSPLSTKAFSNTLKNNLSLNINIVNQVTQQQQVANCTKYFSAVHGRVNSESTFFNSSEFLLGDSATELNVPILYESGIVLPEENLKHQKPFESSCYMQPFTSTSNDRSRSNTPVTNGLISPPVTPVHSTFFGRSPNEVIYGQNSQIPAQQHLNQPQQQLQNLQPSPQQQQIQQHQALPQQQQHLQPIQQQLLQPTLQQQQIQLFQQQLQQQLKQQHIQQQQQQILQHFPLVTLPLQQQSLIPQSLISIIQRDQNPPCNTLYVGNLPIVANPEELEMLFSRCKGYKRLCFRMRPNGPMCFVEFEDVICAAQAMKDLYGVPLTTHNIGNGIRLSFSKNPLGVRLNTQRNNTQPSFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZA7</accession>
    <name>A0AAD5XZA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002386</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000179">
        <property type="protein sequence ID" value="KAJ3222349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZA7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051559">
        <property type="entry name" value="HIF_prolyl_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907">
        <property type="entry name" value="EGL NINE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907:SF26">
        <property type="entry name" value="HIF PROLYL HYDROXYLASE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="5">
        <location>
            <begin position="16"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="319" mass="37129" checksum="48642F3DC76631B7" modified="2024-05-29" version="1">MNFSLATAALKNLKSHGYVVVDNVLPEAVAYNYFNEILNVAEVNQKLLTKNSTILKYKEKTFFFDKPNIGEFDLSVEKVRAALPKIHSYLNDYSLMHLLNTLDLFPHSKNEFFSQTVKAQINFGNNGCFPIHLDADYLNLDDKRTVTSILYLNDLSDDGGGEIVLYPFPYKKIIVKPKFNRYENEFVTQLLIVTRMVLFSSKFCFHRVLKTKEPRICLTKWISTENPLKYDDASLELEDSLCLPQNRIYVSKVLLKDEWRLSLKESQLENCSTILIDNLKNDIKIIENKLQKIKNFQTVFKNFLSETKDESNNLKIKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZG3</accession>
    <name>A0AAD5XZG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH dehydrogenase (Ubiquinone) complex I, assembly factor 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NDUFAF6</name>
        <name evidence="1" type="ORF">HK099_004680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000338">
        <property type="protein sequence ID" value="KAJ3219461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZG3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="249" mass="28334" checksum="207929B4088A24F2" modified="2024-05-29" version="1">MNKKNLDICSNLVRTFDYENYLCALFSPKEVRSCFFAIRAFNVEVAGIREKISDPNIGLMKIQWWKDQISNTFKGKPPNHHVTLLLAESLETSNLSINWFNRILNERAENLNDPQYNTLEELENYAENTSSSLLYLQLEALGLKNVTTDHVASHIGKAVGISTIIRATPYHVRERRFYLPTQIAAKVRNDFKLSTESVFRTGPSSELSDVVFDVATCANDHLITARSQAPKLSKQAIPGLLNIVFFKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZL4</accession>
    <name>A0AAD5XZL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ferrochelatase</fullName>
            <ecNumber evidence="12">4.98.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_004460</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>heme b + 2 H(+) = protoporphyrin IX + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.98.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.98.1.1" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000315">
        <property type="protein sequence ID" value="KAJ3220126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1400:FF:000003">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108:SF1">
        <property type="entry name" value="FERROCHELATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 12" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3220126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="349" mass="39354" checksum="9742B4A43D040DBB" modified="2024-05-29" version="1">MITSNFKWLYPRNKTLKIFKRLSSTSNATAILLLNMGGPANSDQVHSFLLNLFSDNDLIPLPFQKYLGPLIAKRRTPSIIQQYNEIGGGSPIRMWTEKQGEALVKILDKINPETAPHTPYVAFRYAPPLTAETLQQMKKDGIKRAVAFSLYPQYSCSTTGSSLNELSRQLKIVDPENSIKWSVIDRWHSHPSLAQAFANKITEKLSEYNEQDRQDVTILFSAHSLPMTVVNRGDPYPAEVAATVQKVMENLKFSNPYRLIWQSQVGPQPWLGPQTGTVIENYGKQGKKNLLIVPIAFVSDHIETLFEIDLEYGEVAHKHGISGFKRAESMNDDPMFIKALGNLSLQLCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZL5</accession>
    <name>A0AAD5XZL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4281 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZL5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025461">
        <property type="entry name" value="ABA4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14108">
        <property type="entry name" value="ABA4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="17963" checksum="4BB90C606C80B97C" modified="2024-05-29" version="1">MSIIEENIHHIFRFASNVALPGWILLAVAPKWKYTKLFVKGSVIVNCSIYGILIVKAIDSKGMPDFSSWSGVLNLFRNGAEPGLLAAWVHYLAFDLLTGLLISNDAADNQISRVYTAPFLFSTLMFGPVGFGSYILLRPFLGATTPFKSFNYLSTDKSTKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZP5</accession>
    <name>A0AAD5XZP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005290</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000403">
        <property type="protein sequence ID" value="KAJ3217931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZP5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF295">
        <property type="entry name" value="AZ2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3217931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="433" mass="49793" checksum="741F53CAC5221A2E" modified="2024-05-29" version="1">MIQTDNEREISEVLSIYNTPPHSPNQTSQPSNSPFHNYEHPIFPVNKQLQIVNYDTLNARRRSLQPNSIHLNTNTNNFNNFKRRPSFVIETPYTNPTSGNEILTYNPFFLSSFNGTNNESGEKIPDQSCQPLSSDSYFNTKYPDLNLSNNDVDTNINSQSNNQSTILFNSFSSELPQNLNIKNNLQQQIFSASEENVIRRFQPDYYPVEQRRHSIQLIPNPQNANYFSILGDTSISNSSTSTFQNDFHQYDRRQSCIDFGSNQNLKYSSINEDSLNLKLEDFKVKNENFEEENTKAESTTDGDTEFIPLVQGFSKNSKNSKKIAKSYPCHICGRNFARKFNMVQHARVHEVDRVKDQLCPICSHGFYRAADLNRHVRTHTEKGQHVAPCGKSFSRPDAIERHIKKTKCMICTEFNKIQPSSQKVAKITVKNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZY0</accession>
    <name>A0AAD5XZY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000752</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000119">
        <property type="protein sequence ID" value="KAJ3223732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZY0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="298" mass="34646" checksum="8A596F00431AF1C3" modified="2024-05-29" version="1">MSLVKKTLEASETDSNFDFDSYLVDLIIKDAKSINNKNTNFSPSFNEVDEAYHLKPNIKPNKIFLENTIVNTTQHNNSLLKKLNITTRNDSAKFSSKSSNSKSTTHSITSKKRKNSELETSDWKRKYKTGAEDDSELNKPNNNTDKQQKGIAKGRGFMEEGADRLDKYFNKNYNPNLDADNFDDTNMDIYVENLIEFAEEKKKEKKEAKKKKKEENRKKKELEKEEKSRLKKLKKKSDKREEKEVVCVDSQSDSDDSKYRRKDTNSKSNFDDGKQKDADIFIPLDVKKPIRLDLPTKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0G2</accession>
    <name>A0AAD5Y0G2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0G2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="124" mass="13746" checksum="D4F46CFE9EC94010" modified="2024-05-29" version="1" fragment="single">MLKVEAETEVAAALSPINDPPPEYSSIVPSSTELSSAEQTMSDLTQQLFDTSINQFKASPDVENFSLTVKSFASTKTNSEKIILKTFNQDFLSVEVKHFGQPEIINNVRFKAICVDKNFNVVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0S8</accession>
    <name>A0AAD5Y0S8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sn-1-specific diacylglycerol lipase</fullName>
            <ecNumber evidence="14">3.1.1.116</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_006742</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:33276"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="14"/>
    <dbReference type="EMBL" id="JADGJW010000060">
        <property type="protein sequence ID" value="KAJ3225469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0S8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046340">
        <property type="term" value="P:diacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF7">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="15">
        <location>
            <begin position="687"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3225469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="983" mass="110058" checksum="BFDA7188B1DD7E19" modified="2024-05-29" version="1">MLGSNQVDNDIGNFNSFSSITNPQIIQLQELDENFIEENSIIGNRPFLLFEPIANLISYFSHTARLSLGAIGLVAHTAIDTASYATSLSLSLYRSFLIGALSSARNVHNSVSRSNETTSREVQLHNGGSQGLFHRVLDHYTNISIATVNHGFSLAELFTLATFHLTSKSVKLSISAATATVHTFDGIFGSTETSRAIASFVQLVRQEMAEEEREEQEKLGMIAKILHPISSTLNSILTMGSISKALTAYACLCHMTVHRTTNFQNRNLIPMYEGVCQDEQTLPKSKFKNKQLTDTDTSQNSLALMENLESNSFSEQNSSTGSKNLIMSMDDDDNESSVLIKWYEEEDDVTTIEIQEVANDPSSSIENILNDPVSIKKVEEVKVYAQKCRSEMEEIDDSNNLIVDAMTNDDKFLVLKSRSSPSTDNHETISTFSRDFSDTGLNWKKKNKTEKSGGIKSFLNGLKKTKNKERNNIEEFNPSENFDFFKNDCSEINVGSSSYYSGKFNSTIEANDSKLPKGLSMIFESTSNVSQTKDGLIKRKSTLKLKPDYNNSNDELMISSYNNLKKRSFLNLNFEKKQIVDENFKLAELAKKPKSHSLNKAKSYPDQSLIKNIDRYIKFSTGAYGRHFLRILGIGKIRELETEGAETILLHKNNTHTSTSSESGFESPRIKPVNSFICLDHEMNCLVLTFRGTLGLSDILVDLMCTYDDLVINNETYKVHAGMLRAAKSIAFSGVFFSIVRDTLIKYPNYGLILNGHSLGAGVASLLALIWSEKLPENTNNFTPHITSSKSKLPPGRPIHCYAYGVPCVASYELSLYSSGLITSVINGDDLVSTISIGLVRDLKAVSLHLLDEKNKGLSEKIIGKTLGFAMLDEKKEEDLEILLEQDEWFWKIMQELRNKSMSSLKLYPPGEVYWCSVANGVAIVEKESNKLEKRVYTKRVQMHKCVDVREMFSEPRFSKRMITDHSPGSYEETISSLLKISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0V3</accession>
    <name>A0AAD5Y0V3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase family 25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006528</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0V3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042137762" description="Glycosyl transferase family 25 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 25" evidence="3">
        <location>
            <begin position="94"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="327" mass="37534" checksum="87496FE2D72EF5DB" modified="2024-05-29" version="1">MALFTFVLFYLLSQSNGISLTDYKSPNFYTSSQMLKFQNERKSLFDYIKKVENSISEIESEIKRVEKSMQSGINSDGLTVDNEDEPANYFGLDHIYVINLDGRRDRLETMNKIFKKLNAKFTRVAGIDKHSDELKKKMKELNADSQKLDETGLAIKLSHLKALKHAEKHGYERFLVLEDDVDLDLMVGELLPLMLAKLPEDWGIYYLTYTKNASPYPKHNSLIYTLDKYVTGNLALVYNSSVLKKIQKFAIIDKTNTYDYMLGEMMSKKSEEYGIVGYASDFILAQHMGSTPENPSDNLDLNELLWSDKYVAEELLSSTYLSLSTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1A9</accession>
    <name>A0AAD5Y1A9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_004411</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1A9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase N-terminal" evidence="10">
        <location>
            <begin position="23"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="9">
        <location>
            <begin position="278"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3226667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="368" mass="41763" checksum="47DB36A273DE61EB" modified="2024-05-29" version="1">MTVGFTAKTLEQIKLFASLPQTPISLKKMTQFGRVPSPGTLIRASQFMRDELQIRLAHRVVELENLPHGLSEMNSVKKVKQWYTQSFHDLISFPHPSVSRVPADFVLQNNTELNGNEGQEYYDPLKTTALIPQSVLEYNQNFSKLLEKIKNRHDPVVSTIAQGVVDIKNVWKKSKKFSSTQQLPLEIQSFLDRFYMSRIGIRMLIGQHVAISKASFDHNSVPENYVGIICTKTPLMQVVQDAAENAKFICNDYYGLWGGPEVKFIGKENITQDFCYVPSHLHHMVFELLKNSLRAVVERYGIDCEDFPDIKIVFAEGKEDITIKISDEGGGIPRSGLPLIWSYMYTTAENPLLEEDFSKNDFKAPLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2J7</accession>
    <name>A0AAD5Y2J7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006479</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000056">
        <property type="protein sequence ID" value="KAJ3225646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2J7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="8">
        <location>
            <begin position="163"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="492"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="565"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="643" mass="71483" checksum="227D291DA9E64816" modified="2024-05-29" version="1">MNERYPNHTSTTNSINKSLKNSKSNLTENSRLEKPILASADYDSPSPSPIKLSMPLNDSSISQKSPLKIEKQRGLTLTTIQSVSSAQPISKSRELLIQISADSPTTQKSKLSGGIQKSLEQLTLHSKSKVKSISNNELLECLISTKNFTEPNTLNEKLLTVPIDLRSISAFNILHIKNSLNINIMPLLIRRLREKVLQDFHLEKHLTSKDSRDAIEHYREQYKSDLIKKVRVVVYDNEMPENTSDTEAWAFVEIIYSGILCNFLEGRLQENPLQRETKPVEVVYLKNGFSSFTSLPNSFEFLERKQDNFGSPMTIVSNNFSLVTDNELSTENISVQPPSNGNSQLNLNSSLNYSNSRFASISATNSPLPKTENVFSNSLKLSGNGNLNALTINSGSGGSEHSLAKKKRSLSILTTPPSPSPFTLKNNKIFNSKNSISENCGLNVGDTPKKGSYSLNLDSSLNTSSKLSIGENSNTFLSDYNSSPPMSAIFSAYTLIRPYLYLGSDVIPSSSNAIEELKDLKITHILNVAHDVILNPALEENFGFLWIPLKDNLEQEIYDDLKKACAFIDAAREKSQDSVIFVHCKAGKSRSATVVVAYLIWCEAMKQADAYEQVKQLRPEVCPNLSFVMELNRLALEKHGIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2N6</accession>
    <name>A0AAD5Y2N6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleolus and neural progenitor protein-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2N6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052835">
        <property type="entry name" value="Nepro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027951">
        <property type="entry name" value="Nepro_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34761">
        <property type="entry name" value="NUCLEOLUS AND NEURAL PROGENITOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34761:SF1">
        <property type="entry name" value="NUCLEOLUS AND NEURAL PROGENITOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14780">
        <property type="entry name" value="NEPRO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolus and neural progenitor protein-like N-terminal" evidence="2">
        <location>
            <begin position="35"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="374" mass="43589" checksum="388DE40025BAE8B6" modified="2024-05-29" version="1">MKDWNIKDPIKPTPEPYINLHELKEFTLLDLSEEDFVQKLHIYKRNLNPKELNVEIDILKRLKYKNKNQQKSSLHFKKFILVHKLLKNLKMVCIEELIGEILKGLVREKKSNSQTFVPKLPSKQFLYFILTRSTGMFVLLEKICKNSRVAYIEFRNLAKQTYFMPISITAMASLSKISLISKNIITHLEDFFNFIKKIFRVYPVIPTEESSATNLPVSLSAFLDSIKQKKATNKKQKKHSQNDNSEDNMNLEMEENFNAVNQSEVSELCDAFWGNLSSKKIENVSFEEIGASIKPENIKSELFEKKSDLVTEKEIIRPVQEKEVIANKNITIKETVSKSNKKKKKLHKQIINKDKSKKADQQKKDEIDEIFGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y384</accession>
    <name>A0AAD5Y384_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-alpha-acetyltransferase 38, NatC auxiliary subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">LSMD1</name>
        <name evidence="2" type="ORF">HK099_005565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000044">
        <property type="protein sequence ID" value="KAJ3226096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y384"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06168">
        <property type="entry name" value="LSMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034110">
        <property type="entry name" value="LSMD1_Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF5">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="1">
        <location>
            <begin position="8"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="83" mass="9412" checksum="6D15AB6F3ADB0D5E" modified="2024-05-29" version="1">MEKNPLAEFKTLIKSYMNQRTKVYITDGRTFEGLLMCTDRDCNLILSGTMEVKDGIERHIGLTMIPGKHITEVLSDADESIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3G1</accession>
    <name>A0AAD5Y3G1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3G1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="433" mass="51994" checksum="5753D583AFDB7469" modified="2024-05-29" version="1">MFKNNLNLLNFKFFGLEKEFFLFNNASDNATFTDEECLTDFELDGFGFMMISFPNIWCLNETFNNVEEVKNWEDYFFKGKGRHTDFIRKIGLNKENEKFKELIWNEYSIAHCAKIPKHFQMKEQKFLMRLDVLSLELEKRVLDYLLLKSEGNPHLRDDIKIFKFLNNKSSCTNEKKKKNEFNSRLILIYLLILSFFEEFQNFKIFFQNLFLINYELNFEDVYSCNEDNRDNIFASIFNWKESYKLEFLKILIAKNENDYYSATNINNRESVHLKKNFFVAVKKFLNLISRNSMLKKLSFEQKQNFDLIELQKISNKLKGGKQFLLDYVKLLLEGVLILANLNTIDDKFLKKFLNFNKLYETLILMCLDLTKKINVNVDVNYIKSNFLSLLSENEKMNYLPKDPTNEDDGCRCLDYKFRTYFYINEVLNWIEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3V8</accession>
    <name>A0AAD5Y3V8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)</fullName>
            <ecNumber evidence="6">1.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_002886</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.12" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3V8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18126">
        <property type="entry name" value="GAPDH_I_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000001">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000266">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836:SF76">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="16">
        <location>
            <begin position="464"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="15">
        <location>
            <begin position="699"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="180"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3228381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1020" mass="114117" checksum="7BE176949145DED3" modified="2024-05-29" version="1">MLQNSNSPQTEQSQNKTATKKSTTNNSISATTSKTKKEKLPKKVSKQKAASQSQIPSVTVFTENNVEWISFTYSVKGLVKEYKIRTDIDNVKLEDIPNEFKSNNCVYPRAFVNKLDYTGNRWDYETTVNTFGWKLCYVNPDSLCGKRGLIQRAVDSYRNRFPEMRSRRVVRQEKLINGTLRKRAERPSDLDSDSGIYESVNSSKLTDSGGNSSNSLQASQRSNNNSSNSLVIPTSQSSTSLQYDDNEEFFVEPPTKKAKFPKTITFETVLNSIPVKHRIRVDIETVQVDELLEDFKTINTVFPRVWKVEQKNYTFGPPSRRWEYETSMNDLGWRLAWLNSAKLSGRKCLLQRAMDTYRQRYLEDSWKPRPGRRVPFQLPTLSHSQELLAEMNPEEASQLEEAANGLLLVTQRYSQEDNSQNSNLFVEDEKKNSLSYPAITSESNTGNYIEEALSEVGDDNNANEETGMLKNEDEEAATLIDPVTPENAYKVIDKENVELVSILTTHHHQYALFLDHSGGNKTIFRKYPNISIFGGDDRIPALNFRVSHNDVVKVGNLSLRCLHTPCHTEGHICYYIEGEEEKAVFTGDTLFSGGCGRFFEGGENGGEKMYQNLIEKLGKLPLETKVYFGHEYTKSNLLFAKSIEVDNVDIKKKLEFCESNQCTVPSSIEEEYKINPFMRVNKLKAKFNSEDPVFIMDKLREASLEKPDQVRVTHINDPFITLDYMVYLTKYDSTHGKFKGQIEHKDGKLIVNGNAVSVSFCKNPEEIPWGTSGADYVVESTGVFTTNEKASLHLKGGAKKVIISAPSADAPMFVCGVNLDKYDSSMKVISNASCTTNCLAPLAKVVHDNFGIIEGLMTTVHSVTATQKTVDGPSGKNWRDGRGANQNIIPASTGAAKAVGKVIPELNGKITGMAFRVGTPDVSVVDLTVRLAKPAKYDDIVAAVTKASQGDMKGVLGITHDEVVSTDFTSDTHSSTFDVNAGIALNDTFVKLVAWYDNEYGYSHRVVDLINYVAKVDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSN0</accession>
    <name>A0AAD5TSN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002042">
        <property type="protein sequence ID" value="KAJ3199763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSN0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="298" mass="35109" checksum="0C35A15733D1AFE4" modified="2024-05-29" version="1" fragment="single">MNKLLRSGLNIGSSVQSLLKSLTVKSSNQIQVKPIPDSIAESKTPIITYPWLLSTSKMRQEEPTFWSTIKQRELLYPEIERVQTHHLKKPTYDFPYYFYDDIKEVIEELFLVDLVSGTSECNTMVKSLNNIFAFEFMELKKNNITLEFDFKTEDNIPEFNTRLVQVLCTYGAYPIPPGYVAQVWPTYTLVVPEEELLFKSYDYQKKLQKIAMDEGVYIKVDTQLTFTNGVEFILRDKNGTVFFRDYRKRIDVQFCTPHFTPWDEIYELDSEGNWQLRFKWRVSDIDYLISGVFLEEYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSS6</accession>
    <name>A0AAD5TSS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin carboxyl-terminal hydrolase MINDY-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FAM63A</name>
        <name evidence="3" type="ORF">HK099_003210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002132">
        <property type="protein sequence ID" value="KAJ3199353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016807">
        <property type="term" value="F:cysteine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007518">
        <property type="entry name" value="MINDY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033979">
        <property type="entry name" value="MINDY_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063">
        <property type="entry name" value="NF-E2 INDUCIBLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04424">
        <property type="entry name" value="MINDY_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MINDY deubiquitinase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="178" mass="20065" checksum="FBC2A46A42D7A26A" modified="2024-05-29" version="1" fragment="single">MNETNSNGIKLERNEDEIKEVVNQSETDSKNESNKKSVPFQQPLVDSNDVKDVNYLKPKKKILSQDIDSYQVKQISFFGQLFNIVLQNLNGPCPLIALINVLSLTKKINIPPIPTTSEKLLDKLNGYLLDGNLNLSESDLLKVLKELPNLKTGMIVSPRFDIPMSFVDSDQLLVFKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU55</accession>
    <name>A0AAD5TU55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001490">
        <property type="protein sequence ID" value="KAJ3203006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU55"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="91" mass="10225" checksum="329C7E10482B9F79" modified="2024-05-29" version="1" fragment="single">MTTLVVSLTQINLIPIWLGGTIIARDIGLIIGTAYYRYTTLPDPKTLKRYFDFSLVTAEIQPPLISKLNTLFQLSLMFSTIFIPAIFTGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUY4</accession>
    <name>A0AAD5TUY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000476</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001108">
        <property type="protein sequence ID" value="KAJ3206667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="58"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3206667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="468" mass="51202" checksum="515984E89F181B81" modified="2024-05-29" version="1">MSATLTISEEEKDQNNQKKGNLTGEQDFIENIHNDILSQPPTESELNDLKIKSEGSLKPWLVVLGSFITHFIILGILYSFGVFQQYFLSIKLSSASNVAIIGSIGLGILPFFGFFSGRLADTIGYRVTMNIGTTIIFLSLILASFSSELWHYIITQGFLLGLGSSLTYFPAVSAPAFWFEKQRGLATGIAVAGSGIGGFVFGIIIEKLLVSVGLQWTLRILAIIAFVSLVFSSGLIQVSKNQILENSKEKVVNSIFPRHLFKNPVFIFLFLMPFFASFGYTVPIVYIPTYVMEHLDLGSKEGALAVSLFNFASSVGRLLIGFGADKFFGRLNSYIGVYLISGLTTLLIWTFSESYAVLIFYSLSNGFFAGGIISLVPVCIPELFGMQSLASTIGLFFSAHSLGFVFGPIIAGKLLEQNINFNGGIDWMGAIYFAGGIQLVGTMFGVIAIVLYSKWRPLEKSKTDINKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV08</accession>
    <name>A0AAD5TV08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001201">
        <property type="protein sequence ID" value="KAJ3205466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV08"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017943">
        <property type="entry name" value="Bactericidal_perm-incr_a/b_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55394">
        <property type="entry name" value="Bactericidal permeability-increasing protein, BPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3205466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="264" mass="29013" checksum="1A423E78BFD234E3" modified="2024-05-29" version="1">MSHLLTNLQFTEGLNLAFEKVLLPNINNLLSNIIVNSKLDPILVLAEDKVSTSINFGLVEPNLNATYKLSNVKGLSKIKLTELQILECKMCEVQNDICILKCKGGMNKIDISSVEIKGNANTKVGLNLPEASLSGKVESLGITSNFLATAKLKTITGFLFNSYEITEVTIDSINCDFKNVNVYVDGLVGIFNPLVNWILTLIENVFKKSLTSVICFAFKNDIQKTISSLLPIPIEFQIPTINSAYNGALSAYHLINLARTVEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV16</accession>
    <name>A0AAD5TV16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ETFB lysine methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein N-lysine methyltransferase METTL20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. ETFBKMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001083">
        <property type="protein sequence ID" value="KAJ3207039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV16"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050078">
        <property type="entry name" value="Ribosomal_L11_MeTrfase_PrmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43648">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43648:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041945449" description="ETFB lysine methyltransferase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3207039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="234" mass="26637" checksum="E9C68D3C53B81ECF" modified="2024-05-29" version="1">MRGLWATNWISGFILTELMLRSNEFCNFSTEYPSLLELGCGNGMSSIAAAINGKFNVSTTDFDNNALTLSKENAALNNQTSINYFTLNWHNVPSNFPEFDMIIGADIIYMRNSLISISNLILNKLKPNGIAILIDPGRCYVEEFLEHLKAINENRILLLFNLITKTNFKNNFKFVKSLNVLILQKLDSVVDIERSNANFKVFYSHIDKILDQIHVNFTENRVSDNCNLEYGFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVD6</accession>
    <name>A0AAD5TVD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alginate lyase 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001088">
        <property type="protein sequence ID" value="KAJ3206963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVD6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042050380" description="Alginate lyase 2 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase 2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3206963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="25876" checksum="22384CA32D8B141D" modified="2024-05-29" version="1" fragment="single">MKINLLIALNLLATIEAFTVPFFRLHKREANPFDLSYWLLQVPSNTFDDWVYPPQLTLPESRTVNSPTYGYNNYLNKGTSVVLSADIRDLVGKAGGAGARTELREYTRSSTPDQALWTLSTGKHIIKGSLSINNVASGCDSSNGGSVTAGQVHGGPGEADLVSLKYYADNGPGGTQGGVTGKTKNGKPYLRGLNFIINRNGKISATSLDANYKLGTKFNFEYKFEDSTLTFTWMNATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVM7</accession>
    <name>A0AAD5TVM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000971">
        <property type="protein sequence ID" value="KAJ3208895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVM7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanovirin-N" evidence="1">
        <location>
            <begin position="38"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3208895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="158" mass="18133" checksum="69A7DEC557C964EC" modified="2024-05-29" version="1" fragment="single">NEDEIEIKAQIENCDKKNSSLKIKKKKGEENKTDLYKCFSKSGKNFELENDTILTCQLESSEGYVSAKLDLDTIFFNQNGRLRRGFGGFKQNSKNIKLEKVGDNEDLHLTADCERKDKTFRTNSWVNLDGYFGNKNGKIVYNKAINKKKFGKKVTKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVP7</accession>
    <name>A0AAD5TVP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Annexin B9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ANXB9</name>
        <name evidence="8" type="ORF">HK099_000193</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001030">
        <property type="protein sequence ID" value="KAJ3207821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVP7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000002">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0041">Annexin</keyword>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WW" evidence="7">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3207821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="544" mass="62368" checksum="1B317A9095409AE7" modified="2024-05-29" version="1">MSYPGSYGTKNNQKFPLQHCQQQIPPGWITQFDQKSKRNFYVDTRTGQSHWVLPNLVHHPQQYQQPAPQYQPPQQYQPPVIQQYQPPHYQSQIPQHYQQPMIPQNHRPANFQYQQSALSHNQIQQSLPNFHQNTVEPHQFNDVSLPKHNTFPSYKPQSLPNLHTFKRPGYQSPPSLDYQSPHTSHYLPATQVYENVASQSHPPARLQNPPPAQQATASPQYQYIKPSSMHRISWGKPLKHDDAVGQAKSLIVAFNDSEKARDEALISFLSTYSPIQIKQVDEIYSKLTSGKKIKEKICDKGDFGKLLEALLMYEEGEFDAFCIRDALTGGLLKDEDTLIEILVGRTNEDINSILIAYNNLYNIQLNTEIKKYFTGNFGDFMVKGVLQGRMNVNAEADIDCNTLYTLGENRKGCDEEAFINIFCSRTLEHLKEVFELYEKKYKKDIKTVIKKEFKGDIEKGFLAIVKSAIDNPKKIAASLRNAMKGFGTNDKQLIRLIVTNREPKRMGAIKRSFEESFGKSLFSYVKDDTSGTYRALLCRLIEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVU0</accession>
    <name>A0AAD5TVU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PRP5</name>
        <name evidence="14" type="ORF">HK099_007998</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000832">
        <property type="protein sequence ID" value="KAJ3211471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVU0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17953">
        <property type="entry name" value="DEADc_DDX46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056149">
        <property type="entry name" value="PRP5/DDX46/KHDC4_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23469">
        <property type="entry name" value="KH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="498"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="687"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="186"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="49"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3211471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1076" mass="122022" checksum="4FCCD9464AD01459" modified="2024-05-29" version="1">MSSQSHSTHSTSKKEPSKRERSPERVSSHKSSNRDKEEERHSHKKHHSSHTEKDSEKSSSKREKVSDRSSHRERDREADRSHRDRDYERSSRRDRDADRGRRDSDRGRDRDRGRERDREWERDRDSDRSRKSRKRGLDEKKESDEKRQKSDVIVNSVHTDSLNSAILPAVNVEEVKTGLPKIPVVVLTAEEEKRLKEEELAKAEEEKRRLRKEKLEKWKEEQKLKENTVLTETIPAPAEVIAPPKKNLQLKKTGLTILSFKKNKENTTTPKKNLFGKKLEAEKNTVKLNSFFNTQDDEEDNEGAKPKLPSLNLISSSDVNIPVVEEKEEIINGEEEEDALDTFMQNDINPEYEKVKAEDEIKQQQIQLKLASLKKEDFALDDDEVEENVEENIDEDDIMAAAYKLLAKKKDIIAVDHENIDYPEFKKNFYIEPREMAELTEAEVEQKRADLDGIKIRGIDCPKPIERWTLFGLPLTVNDVITKQLKYASPSPIQAQGIPAILSGRDVIGVARTGSGKTLAFLLPMFRHIKDQSPLAINDGPIAMIMTPTRELAVQIFRECKLFLKYLNLKAVCCYGGSPIKDQIADLKRGAEIVICTPGRMIDLLSANSGKVTNLSRITYLVLDEADRMFDLGFEPQVMKIIKNVRPDRQTLLFSATFTKQTEALARKILSKPLEITVGGRSVVCKDVTQIVEVIAEEKKFERLLFILGKHVHNDKNAKALIFVDRHEVADNMLRDLIKRGHVCQSLHGGKEQMDRDSTIADFKSGVTQIVIATSVAARGLDVKQLSLVVNYECPNHMEDYVHRVGRTGRAGNKGTAYTFLTHDQDAYAIDIAKALKNSGTEIPADLKALCENYMKKVKSGKVKLITNKGFGGKGLNRLEAERETARKIQRITMGGDEGDEPVEEAEENGDDAFSKALEKFAPSKETKEAVNLWDEALAKNPAVADKLENVSAVIKNIQEMLKKPKLDVNGEVIMANTFCEEIPINDVPKLARIKVTQKEQITIISEMTHASIITKGKYFVPGTTPNFNEKKLYLEIKGETQQIVDRAKSEIRKLLLEHTVTSLQGESSIGRYNIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVU1</accession>
    <name>A0AAD5TVU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008723</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000994">
        <property type="protein sequence ID" value="KAJ3208453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVU1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="527" mass="59633" checksum="5B80930569244ECC" modified="2024-05-29" version="1">MSEKLPIANGMEEFKSIANNNIDQNEKDSSLEVLLMPFNYNTNSTSRAKYVPPHQRLAINASNYHNNDLDSNMNRLSFTDNNNSHASYKFGSPKRDYNHLSFDHKSTKSESFSYNNTRTGNSYIARHNYGNEQFNSSSQDFKENSSLEYQNNTWNNHKVSLPYKNWRTENGEMREKLTYNNGVSVKGRYSQYKDSSLISNSYESVEYLPNRISGTSNTESRSMTSLNSHSRISNKTYHIGSPSMKSKNFNRKDSIVSNISRASSINQDDSSSSRGESKGNYSSLPTSLMEHSKFISDMLNQPTKSIQTLGGEQGITSQINILREQVDELKRKFSNVIDKEVIDSSITENTSNVGNNLNNHDNNSTQEENFRRGVPPLSPPLSNLGSPTKQKSVYPTTTNSPSSQSKQLLDFEVENIKIKNEKQNNQNSNTIATEEQNRMEFFNKTLTNLLSLSQELFDILDDSLDDGLSGDDVLSLRELCRVQLASIKMLIKVLSEIASDSKPKIENKNNNNLLDYSSSRKGKERAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVW6</accession>
    <name>A0AAD5TVW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HEAT repeat-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HEATR2</name>
        <name evidence="3" type="ORF">HK099_007929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000815">
        <property type="protein sequence ID" value="KAJ3211767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVW6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052623">
        <property type="entry name" value="DAAF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056497">
        <property type="entry name" value="HEAT_DAAF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057978">
        <property type="entry name" value="TPR_DAAF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 5, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216:SF2">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24573">
        <property type="entry name" value="HEAT_DAAF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25757">
        <property type="entry name" value="TPR_DNAAF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein axonemal assembly factor 5 TPR repeats" evidence="2">
        <location>
            <begin position="38"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein axonemal assembly factor 5 HEAT-repeat" evidence="1">
        <location>
            <begin position="324"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3211767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="903" mass="101713" checksum="86581D9B5D79109B" modified="2024-05-29" version="1">MMAQVEADQSLNQQETEFLEEITQKLQRDLNILQEKGTDRTSKRKALERVKKESEKVLPKPKVASSLLKSTLIKPLLILFFDKIEKCRDLSISTFFNLANVVPDPENFLAYIIPSLVDRLSGTEILEESEEIRLNLIVGLNDLVNKCQVKISPFIEEISKIVTKTLNDPFPEESCNLVQSMAKQSPQSFAFISASVSKALIPTLIHRHSGVRTVGLKALKDALIVDPAGLDDVLDTLWNLIHDKAPSVRQTLYTCIFEVQMKLMDRWSLAYKILPLLLAGCSDELPNLVDICQNYMIEVGKLYEVEWEDRVKEELQVVPLAGQQLDRPRIGSKHILRENTQKILNKLLELMQDWNVDVRLKSSRILNSFLWYVEECITGYVGTILPILCKICSNDDSAVVIAAIKIGQSLGKYVNPNVYLEQILFFAKNGSGGSTPYRVGSLKVLQSLIEGSSAEFFCSKTSENIRTNVVQLTETLNDKELGGSDNNIILTEVVGCLLATVSKLSEATKTEMEIVDVKSNKNDEEYHIFLLLIRLISIDGDEKYPEWSSICGKASKALELLANSLKLSSVTDVYTLFMNRILDWYALGVSNWSQYNSERKEFESVVKGCGPFIGKNPETLSTVIKIICCLTEPEKEVIVKERVMRLVLYLLQNSKETINSASLLYSFSFVLLKAILSNSVWRAGKKIATLRGISIDCLFALSKGDEEKEGYVGFVAISDLVQQLDENDTEKTFFRTQVIPNLINCLDDDLSSTRVATLNVISIFLNTKAFTSVAEYKILYPELVKRLDDAQDSIRILAADTLTNFVISLNKFTSLIQNQDLNLNNEKKYVELKLDDVHFESLIKSTTVHLDDMNNEVQNAVLKVLIALAKSVCCDNNLIKDHLELVGNKHRSQVYINQIKNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW47</accession>
    <name>A0AAD5TW47_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008346</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000902">
        <property type="protein sequence ID" value="KAJ3210219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW47"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="6">
        <location>
            <begin position="31"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3210219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="262" mass="29860" checksum="EAEB0D1D9863E0B1" modified="2024-05-29" version="1">MSLPILITNEISFFESTKNVAYVTLVVDAFNFLLAIVNLILSYKTLRKGSTKSVTTLVFATNICWLMFSVITIICDILSVNFNINVWNFPSAHPMWIVLIIRFFSYTLSLLFYQILTVKRFSTVVQSIHQTPIKLHYILYFIAIAFNVTAILPAMVDYFCCLLDPNWMLDNGEGVCNGLLVMLNFDSYSSYYSFEFTGGLLQVFGIPIFEGVLGLTLLMILSRLKSFKDSPIEKELRKEKVNNDIKAYLLLFVFTVFASGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW50</accession>
    <name>A0AAD5TW50_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001697</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001502">
        <property type="protein sequence ID" value="KAJ3202916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW50"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="248" mass="29229" checksum="ED0E4E084AF64595" modified="2024-05-29" version="1">MNLESTKKATEGMQNTFTEQLLNHQEELLFQSDLKAENILLSKKVQKISSETKNLMYYKNNCQLLQNLVRELIEVNELQKCTIMETTEQLELMRSENFYLKNSVYENITDMNEDNDEISIKKTMFGELEDYLVKEGYGSYENVKSEKLNYSVLSKIMTIFKTRVVESDMIKLNKNLIKKPFDIEKLTSISNDILTEIDLELTEMKNQLHLNEEKEISFFNFVFELLNDIIKLRLTLNNYALSYCEKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWK5</accession>
    <name>A0AAD5TWK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000768">
        <property type="protein sequence ID" value="KAJ3212664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWK5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="240" mass="27633" checksum="4B5B09CAA8E954BF" modified="2024-05-29" version="1">MPFGLTSYVFNSADLSFVLGMALALTLLIVLKSMKNLKRNTLLVYLTFIAAITQGMNLITMQMSSSHRWTNTECWCCAALIIRATIFNDKFTKYLKVFSWILLFCLTFCNTYAQFIHYELISEPDLMECYNNGKHAKQMHQSGGDEQSKVDGVQRNYKNFMMNLIVSDFGFIWVQFLVFCATLENLFLIYITQNISVMLSGCGYVIIPKKHLILGGKTLNTKVEKKEPTEERFTPYQYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX56</accession>
    <name>A0AAD5TX56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000657">
        <property type="protein sequence ID" value="KAJ3214007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX56"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="79" mass="9423" checksum="65FE0BF9A3F85B64" modified="2024-05-29" version="1" fragment="single">ANKKIFFDEGENYKNYDKQSLDTLLKDYNISKENFEIVSRYYNTVELGPVTSTQNNLRDAIWISNLHEENLKRYTDLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX90</accession>
    <name>A0AAD5TX90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alkyl transferase</fullName>
            <ecNumber evidence="3">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000602">
        <property type="protein sequence ID" value="KAJ3214657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX90"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3214657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="254" mass="29208" checksum="0FFE5C111B2BBD9F" modified="2024-05-29" version="1">MDGNRRFAKTSGMKTAEGHLAGFSTLEDTLNWSLKLGVKCVTVYAFSVENFKRPQEEVDNLMELAEEKFNAFAHNSDFIKKNEISVRVLGELELLPPKIRKAAINVTKSTSHHKNAIFNICFPYTSFLEIEDAALEIINGIKSNDINKDDVSEEFFNKLLYTGDCPPVDILIRTSGEIRFSDFLLWQCSDKCSVHFLDCYWPDFSFWDMLPIILQFQALFTPLKEESNPLPNAKITEFLEKIRLKKRLQGEELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXA0</accession>
    <name>A0AAD5TXA0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cofilin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Actin-depolymerizing factor 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COF1_2</name>
        <name evidence="7" type="ORF">HK099_007109</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000663">
        <property type="protein sequence ID" value="KAJ3213942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXA0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11286">
        <property type="entry name" value="ADF_cofilin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017904">
        <property type="entry name" value="ADF/Cofilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11913">
        <property type="entry name" value="COFILIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3213942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="140" mass="16053" checksum="8967D66F2F65BD15" modified="2024-05-29" version="1">MSSGVGVNDQAVSVFQDLKLKKKYKYIVYKIADNNTEIVVESTVEEASYDDFVKALPANECRYGVYDFQYEVPNEGQRNKILFYTWSPDTGKIKQKMLYAASKDALRKKLDGIYTEIQCTDLSELSHEAVYEKVILITCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXF5</accession>
    <name>A0AAD5TXF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40s ribosomal protein L44e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL44_1</name>
        <name evidence="5" type="ORF">HK099_000275</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001059">
        <property type="protein sequence ID" value="KAJ3207361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXF5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3207361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="105" mass="11982" checksum="9B9759223A075816" modified="2024-05-29" version="1" fragment="single">VNVPKTRNTFCKGSQCKKHTPHKVSQYKTGKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTVCKYKMQMSLKRCKHFELGGDKKTKGAALQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXG8</accession>
    <name>A0AAD5TXG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000580">
        <property type="protein sequence ID" value="KAJ3214955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXG8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="109" mass="12954" checksum="F5E340649965B849" modified="2024-05-29" version="1">MNELKNNNDRYFEKLITITKINELNNSKNTIPEPETDVQDISIGILLNKQIRIIREKDKEDLYKKKEKISSVILSYMYSIKLTYSIETTMKHDPSKYDPNKKEGKRTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXR9</accession>
    <name>A0AAD5TXR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007008</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000646">
        <property type="protein sequence ID" value="KAJ3214142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="180"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3214142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="187" mass="21918" checksum="886CF124D1B29411" modified="2024-05-29" version="1">MTCIMHTYIEDIDVNRTELYEIDGVNLMETLIFHPNKARRRSKQIANLIKKEVSENKVSKSVRVLVLGSGDSGKSTFVRQLRISHEKLFTLEELELLKYVIHNNIFSELLILINSLPRLSLKLKPNNEFLESAAIIKNYSQHTNYHFEKKLPSEVINTFIKIWNDPDIKECFCRRCELQDSFQETMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYA0</accession>
    <name>A0AAD5TYA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein HSP 90-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HSPC2</name>
        <name evidence="5" type="ORF">HK099_006149</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000512">
        <property type="protein sequence ID" value="KAJ3215904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYA0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="34"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="414" mass="48830" checksum="FE924B266E0B2240" modified="2024-05-29" version="1">MSILFHSPLNDAFSVDFFDDLLTSELKSTKKTKNSKQQFLPQLDVVENDKEYCIQVDLPGVSKDHIDLNMNDNNVLVIKGERKRTLEQSNTDKEHVCERKYGDFERRLQLPKDTSFEEVDAALENGVLTVYLAFFFLLVSIFEIYKVFKNTVETTHLEDNTGTDEIDEPQNQTLLMKLNDNIFNDKQYEYLSYYEKKSLVFQKEDQLLNPSDDEEEVEDSRNCKTDFCLLTKYMKFLKKYISPTKKLQDKLEEKNKNCSSNLKIFVYPFAPERNINLLKQNGWRYICKVHCISAQFSLDLISHKFFLKSCMRTFNPEEADFYYVPYYSHLDQPHTKSFTKTILDMIDTHGKNNTAAGYRNWEHFTKTDSYWWKTRGVSKHIFVNSIGGWVWGRYDYPVNIPGIWLTMEASHYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYA9</accession>
    <name>A0AAD5TYA9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase family 49 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000778">
        <property type="protein sequence ID" value="KAJ3212450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3212450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="36032" checksum="953EEB861211425D" modified="2024-05-29" version="1">MSDNYKIEKHTITVTTFITVDKLPLLLNCMKSYNGLFSVTLHLLSDENLTNNLLTVKTFLNETFPIVKDSLDMHLVIDAYPRQFNFYRNVARYFCRTDLILMLDADFIINKSFAHHMKNSTKVLEKLAKGDSVFILPAFEYRDITENKSIVDYPITKEEVKKRWVSNHIMIFQGNLNKAHVSTKYRSWMKKGVPFKIEPKTNQYEPYAIFNKNYIPWCDERFVGYGYNRAAWWYEIYLSGIEFYVLPYDFIFHQYHVHDNKIRIAEKKKNISKFRKFTREVCDKYTSVVDMVVEKKMKTCLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYC8</accession>
    <name>A0AAD5TYC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Histone chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_006676</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CHZ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000593">
        <property type="protein sequence ID" value="KAJ3214760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYC8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019098">
        <property type="entry name" value="Histone_chaperone_domain_CHZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09649">
        <property type="entry name" value="CHZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone chaperone" evidence="7">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3214760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="15465" checksum="8AB29F37903ECCFA" modified="2024-05-29" version="1">MQIEKKKVDPKSKEKKSVENKLESKNFKKRKPESDSEEDVEEEEVEEEEEEEESEEEVKPNKKEKKTSSSSKIDKKKKKKKRKDSDDESEEEGLSESGSEVSGDEGAVEKKNIIEGGRRTRGKKVNLLSQIFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYQ2</accession>
    <name>A0AAD5TYQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006564</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000577">
        <property type="protein sequence ID" value="KAJ3214998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYQ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="12"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="372" mass="41127" checksum="B8A8BF2D0F154587" modified="2024-05-29" version="1" fragment="single">MTEEETVAEQEVEALPLDSIFVCFSPKIEADVVAEFKESLKPLGGNVVGTVTKKCTHYIATADEWKQKTPNKSRMALDRKDVKIVSTEYLEISIKNKTPADESKYLLDTTRDEQENGSRSSVSRGGRERKPVSSYANEDSPSENENDYIDYPASKKGTPKRGKGTPRKRNSTSKKRKKAHDEDNETGSEEDNDVVRSPKAGTRTSKRTKKSVEESDKMDVASPEKETERGTSKSPEKSAAKEKSASPEKTGTKRKSMSPEKVSKALSKSPEKETPSSKKAKSPEKDITAKEKSKSPEKETTKTVRAKSKSPEKEVTNTTKAKSPEKNTPVMKKAKSKSPEKETQKVTSPQKEGTRANSKSPEKESTKVSMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ04</accession>
    <name>A0AAD5TZ04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proliferation-associated protein 2G4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PA2G4</name>
        <name evidence="3" type="ORF">HK099_005316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000408">
        <property type="protein sequence ID" value="KAJ3217832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ04"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01089">
        <property type="entry name" value="PA2G4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047113">
        <property type="entry name" value="PA2G4/ARX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804:SF11">
        <property type="entry name" value="PROLIFERATION-ASSOCIATED PROTEIN 2G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804">
        <property type="entry name" value="PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="2">
        <location>
            <begin position="24"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="425" mass="47255" checksum="8357AF8483A10E19" modified="2024-05-29" version="1">MNESYYTEDQMEKDNILSIDVITKYKTAADIANFVMKKVVHSTYAGQSISEICKLGDSLITEQVSNIFKKRGIEKGIAFPTCLNLNNIAQNYSPLSHSVHQILTANDVVKIELGVHVDGYIATLAHTVVVSEKDIEATSPLLDVFLGRAADAICAAYYGLEIASRMIKPGNKSVDVKNAIRKVAAAFKCQPCNDTDSRLMKRYILESDKHIPNVSFSKDFNPSSQYDASSHELIRSDMDYEEETFDDFEFKTNEVYSVNIVISSGSGQLRESLDEEFGILQRDVNQKYNLKLKSSKICLETAMKHFSVFPFSTRGLLDIDERLKLGLPECISHNLLCPLPVKEEGANKHSTIAQFKCTLLLMPNGKVERITAGEEMFGLPYVHSDFNVESSGMAEILKLNLKNVGEKLGLMLPSTSGDAMAMTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ30</accession>
    <name>A0AAD5TZ30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ARID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_000823</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001202">
        <property type="protein sequence ID" value="KAJ3205452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ30"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052406">
        <property type="entry name" value="Chromatin_Remodeling_Comp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970:SF14">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ARID" evidence="7">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="538"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="485"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="539"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3205452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="809" mass="93175" checksum="E734320CB8B41810" modified="2024-05-29" version="1">MQNRFLTDLADFLSTHFKVRLAEPVLGGKKLDIQKLYNWVTANGGYWEVISEKKWKRCADKELKLPETCTNSAFALRNIYSKYLYAFEQVNYFKKPLIDVIAEIEKNDNSSHEHDRITRRTVEKRKSIVDNTPMSAPKVYPLSPRRTELLYHQKHFVPINPDDDNRDEKYLWGRNQSRLLLAIESGLPNEIDWALSKLVKISYSCPETLCIESVVPGLIEALINIIQPFFDCLKLNTSKSNFLTTLNNDRLPKFEEIRMFNLTVDQEKELDVVLNVLQVIRNFSILPPNALNFSLQHEIIEILAKGIALDSTSAYNYIKQDCVSIVESLSPYITVRNENDFFLSCMRSFLFTNDRSLIIGGLKTLTNLCAQKNNREAFLNFEKRQPEDFLKRLFELLLVFGDQMLVSCVLDYLYQYSTLGIEPCKKMATLNMPQILNTVNLLIKFLNYENHQPRPILSNIQLEAASRLQTPKFDPKKFSSEKISKSSFNRNVSNINKNLSELEEVEVDVVDVEGDLESKKRRLNDDLSSTLNNTAAFTSLPNSNLSSPVLSKNTNSHSQSSSPLTKHNAVSDTYYNPLPPQIPFQNLGVQYPQQQNVEQHYTGNKCFWKAKGESNYCNLIFQKEEDLIKHVYENHLGVENEVFECHWKECKFFEEKLKKQQIKYQLQLQQQQQNSQLISPSTILPPSNNKSRIKCLTHFQTHFPLTSNTIKFNSNSGNLKNNKINVNNNNKMNISAPNLNSLPDLVGISLTCLLVLRNLAKFSSEGGYQELFFKIEGDLVLLSCDARYTKFISQILKEVGIDYNKNFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZJ0</accession>
    <name>A0AAD5TZJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004988</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000370">
        <property type="protein sequence ID" value="KAJ3218668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZJ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF472">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CPVL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3218668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="402" mass="45977" checksum="0BAE32CB5748659D" modified="2024-05-29" version="1">MLRQKREFFWYFPNKNESSPLIIWLQGGPGSSSMIGLFHELGPITLTANGLRKSMYSWNENFSLLFIDNPVGTGYSFVKNVERTETVKFKNDVYVNGTSIGSPDIKNIFKNLNWKTKDFKNCQGTLFLESVDDMDAVFDGGAKTLPLYNNGRVVCWKICANYIDEKNKEVNDKINLGGIIIGNGLTDPRSQILSHSPLAYALGLVSTSQAKELDRLAQQTVYWIDCKDYLKGSASRMELFSYFKNVTNDINFYDIRSYGGNDWSVMDNLLSNEQFKRAINVPKEVKFFKDPLVAATLAEDIMKSEVHKFPTLLDDAKIKILLYQGNFDYRDGVLSSTKWIEEGIRWSGSKEFSKAERKIRNRSWSRKYKNLNWWVINGAGHLAPKDQGEVVKIMIEEFIGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZJ2</accession>
    <name>A0AAD5TZJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005195</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000396">
        <property type="protein sequence ID" value="KAJ3218107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZJ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031398">
        <property type="term" value="P:positive regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22212">
        <property type="entry name" value="NDFIP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019325">
        <property type="entry name" value="NEDD4/Bsd2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396:SF5">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13396">
        <property type="entry name" value="NEDD4 FAMILY INTERACTING PROTEIN 1/2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10176">
        <property type="entry name" value="NEDD4_Bsd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="472" mass="53543" checksum="E78DBFE213C5D64F" modified="2024-05-29" version="1">MTVIHTTCSQQIINPEISLLSNSVENLNITNQSNNQKQLRETLYHQILTNGQDPPLYDSSKFHHPQTSVTYLVTRPKFFDNCDTIFKNQDGTPAFYIPDPFPCRNWNTQLLRGDKNGPPAINIDKISGIVNINFSNSINSNIRTVCTTSGVTTTKREFEGFDGVKYRWKNKRIKYLELKSYSNTNDDALKNCSKRQQKKNVKKEVIANFELNKSGIDSKLVIYEKEVMVKYEVVHNLSDLEEAPIADSRDLQQSTSSSSTTAAEHVYDIELNTNKTNPQQYTKYDQQQFNNSDGVFNNIPAKPDVYKDEPLPPAYDLPETEQVPPYFEATVSPAVLYGTDGDILIEGMEVGNTFSFIINVIMSMSFDFIGYMLTTMMALTHSARCGSKLGLGITLFRYGIFISTEEYSEEVNEYRYYDPDSDESGDNVTAQNATLSYILMILGFIVILQSSLEYYRISRLRAVILSTENSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZN4</accession>
    <name>A0AAD5TZN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000632">
        <property type="protein sequence ID" value="KAJ3214321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZN4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="277" mass="31758" checksum="BCF3D090B638FF4A" modified="2024-05-29" version="1">MDGEIAIEQARNNDKVLKNSTSNQTLVESDDKADSLNSNSLHENGPQKNKKSIKKIEKLKKLKDELATVKTENEIFKQSLFERDEIIKKLATEKEKYLKKISLMEESAEFQREEYLSMVSAENEPVENASTRKLSEALKTSDDEHQKNLHREEFNYVKNQLKDNLDLVKTLSSSSNELKSANANLEKELNLKNENESELQKRVVDLKSINLSIENENNDLKKQIENLIFRHNDDVNKQLTADSQNRKIIFGLKSTVARLEDLIKKNEKNIAGSGGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZS2</accession>
    <name>A0AAD5TZS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcription factor TFIIB cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_004929</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000365">
        <property type="protein sequence ID" value="KAJ3218764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZS2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3218764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="50573" checksum="F4EEAA59C541364E" modified="2024-05-29" version="1">MEVLHQNKSLCCSSKLVSLDDETGMVCSTCGEVDKQISCMNQFSMDHTEKEFDFNYNLSTNLQVRNRTKTKVNLTVNKINKIRQIISQQMSIAGYHNLVDIEARAQELCENALMIEEKEKKIQKKNLEHLILCCIYISLRENFFTITLHRLATVLNLKKYIFSLGKIFFKLKKIFKLTLVSLNSAQFFNVIFLKLKIHDEFLTKKCSEILNLMQNCGLDLGRRPELIAAACFTFAFGVKLRSTPKAITFLKVAASVEVKIDAMRERYKEVMNIMFEIGSKIAWIKGEFKKSDVFKYYPYILYYSDNLNTRKTESAKKSQLPIDVFSKKNYSDENSSLDSSDEYSEDDLNVETSNDGALNINTDIFLPPSFVKSKNRNLELTAKIQRARKRIKLMQEFFTSEGEEFLNLDEMDTIVEDLILQGQSDETILNKNWKKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZS9</accession>
    <name>A0AAD5TZS9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000351">
        <property type="protein sequence ID" value="KAJ3219122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZS9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042209188" evidence="1">
        <location>
            <begin position="18"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="113" mass="12139" checksum="3794046C9AE9C28C" modified="2024-05-29" version="1">MKISDIIAVVLIQLSYSMPIAVLENQTNNAALPTMGCTTVDNTLTDEISILKFNEHDINNSDNFRDSPTLSVSIKLPCIHTAAVSESTAAPNLAYGYDFINPNTGPAPEGIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0L5</accession>
    <name>A0AAD5U0L5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP-dependent RNA helicase DRS1</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP-dependent RNA helicase drs1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">DRS1</name>
        <name evidence="21" type="ORF">HK099_006955</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">ATP-binding RNA helicase involved in ribosome assembly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000637">
        <property type="protein sequence ID" value="KAJ3214247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0L5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17947">
        <property type="entry name" value="DEADc_DDX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000842">
        <property type="entry name" value="ATP-dependent RNA helicase DRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="20">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="235"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="420"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="114"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="637"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="15">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="637"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="744"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00043999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3214247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="755" mass="84605" checksum="4333AADBF1398D9F" modified="2024-05-29" version="1">MNVYSSVCKEAGELPGYQELALKNRNAVLRESNVSPPESKPTKDIVDQESDDSIADEDDHIVIDPSFSFEFSGGALQAKINSAWNFSQVKSSFETNNQSNSKFSTLDEKIEKKRNENKIPNLEDEDVDVVDGNVESESEETSAADEANKIEQNGSDGQELSSDEDISDEEELAEADNDLEDTVRDKKAAEFFAPEQEIIEEQVETFTEMRLSRPILKGVAGLGFVKPTPIQANTIPLAMKGTDICGAAVTGSGKTAAFIIPILERLLFRPKDVATTRVLVLVPTRELGAQCHSVASNLGKFTDIQFSLCVGGLSTKVQELELRKRPDVVIATPGRLIDHIHNSPSFNLDSIEILIIDEADRILDDGFAAELNEIIRNCPKGRQTMLFSATMTDNVDDLIKLSLNRPVRLFVNSSTALTSRLTQEFIRIRSSKEQHKSAILASLCSRTYKTECIVFFKSKADAHMMKLVFGLLGIKAAELHGNLNQLERLEALESFRDRKVDFLLATDLASRGLDIAGIRTVINYDMPTNYSLYVHRVGRTARAGQAGRAVSLVTEQDRKVLKLAVKNAGAQSHIKNRVIPSSVILKFQKKIQDLKEKVKEISKEEYEEKVFKKTEMEINKGLNSIKHQDEILSRPKKEWFQSQDEKLQQKELGVRNHGASKKEKNNEEDSKNKLKRSPLDGLSRKKKRQRSQFLEEEKEQLKSQKFSVRSAKTSTKPKKVKQFADKINSKPSNGQSTRKKKSGSRFDAEVKGKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0P2</accession>
    <name>A0AAD5U0P2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Intraflagellar transport protein 172 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005171</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IFT172 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000392">
        <property type="protein sequence ID" value="KAJ3218170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030990">
        <property type="term" value="C:intraciliary transport particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000008">
        <property type="entry name" value="Intraflagellar transport protein 172 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000012">
        <property type="entry name" value="intraflagellar transport protein 172 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000013">
        <property type="entry name" value="intraflagellar transport protein 172 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056168">
        <property type="entry name" value="TPR_IF140/IFT172/WDR19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056157">
        <property type="entry name" value="TPR_IFT80_172_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722">
        <property type="entry name" value="IFT140/172-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722:SF2">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24762">
        <property type="entry name" value="TPR_IF140-IFT172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23387">
        <property type="entry name" value="TPR_IFT80_172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50960">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3 10" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="11">
        <location>
            <begin position="1799"/>
            <end position="1845"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="1985"/>
            <end position="2024"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="2025"/>
            <end position="2064"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="2065"/>
            <end position="2104"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="2118"/>
            <end position="2157"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="2158"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="2198"/>
            <end position="2237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00073483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3218170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2283" mass="257077" checksum="B6BFFA37578DA509" modified="2024-05-29" version="1">MNAFNLEYLCYLRHLKTVIPASDAPNRVSAIGTSIQIFIIIILFKAWSPNNQKLAVVGADRVVQLFDETGERKDRFSTKPADPQKTSKPYTICGLAFSSDSTKLAIAQTDCVVFVYKLGLEWGEKKSICNKLIQSSEITSMTWPKEQPNALVFGLADGKVRVGNLKTNKAATLYQTESCVVSTASNLEGNAIISGHADGSVNRFFFDDAVQGAAQGKFVTHRCAPDALAWGESIVAAGCDKVVVFYDQNGKVVQQFDYSNDENVYDFTTAEFNPSGQSVVLGSFNRFHIYNYSVSSQQWSEAAIKIIDNFYTVTALAWKPDGSRLAAANMCGATEIFDCCLKRSRYKGKFEFTYVSPSQVIVKRLSTGSRIVLKSHYGYEITKVNIFQDQFLIANTNQTLLMGDLASCKLSEISWIGSGNEKFYFENPRACMVFNAGELSLVEYGVNEILGSCRTEHMNPHSISVRINDRKFQENVKKVAYLIDLQTINVLDLITGFTVGSVSHDSKIDWLELSGKGTNLLFRDKRNQLHLYDVAAQTRVTLLSYCTYVQWVPNSDVIVAQSRNNLCIWYSVAFPKRVTMFPIKGDIEDIERVDGKTEVIVDEGVNTVSYTLDESLIEFGTSLEDRDYERAVALLETLTLNSDTEAMWKTLSQMALKDDKLKMAERCFAALGDVATTQYLRNLNDVAEKINDEGIHDGIQHYAVKAKLAMLDKQFKIAENIYLEQGKVEDAMNMYQEMHKWNLSIKVAEMKNHPELETLKKNYYSWLIDSGQEDQAAETKEEEGDYTAAIHLYLKAGMPGRASQVLLQRGLTSNSELTERIAASLYKSSLYEKAGELYEKLGSNDRALDSYKKGKSFRAAIELARHVIVLEEQWGNYLVSVSQMDAAINHYIEAGKTHKAIEAAISAKQWRRAVGIIETLESPYSNKTHLLQIAKYFDENSDFSLAERYYVLAGRPQEAVDMYTKANKWEKAHTLATTYMTQDEVSFLYVSHARDMEAQGKMKEAEKLFLTVGEPDLAINMYKNHKQYDAMIRLVTAHHKDLLGETHLYLARTLEGEGNLRLSEHHYVEGKDWKSAINMYCANNMHEEAYRVAKTYGGVTSSKQVAYLWARSLGGESAVKLLTKFNLLDAAIDFATENGAFDFAFELTKFSEKGKLAEVHYKHAMFLEDEGKFKEAEAAFIIAGKPKEAILMYVHNENWESALAVAEAHDPANVAEVLIGQAKVSFEKKEYAKAESLLLRAQRPDVAINLYKGVRLWNEAIKFAKEYLPNKLAEIHEEREKYSLSQSNNGKDEILNAAKNLEKQKDYSRAIDMYLRLSPKMVDDLTLEQHWVHCVELASKFCGPERTRETILAVCTRLVEINKHESAAQVFVNAGGMYKEAIDCCIAASLWDKARQIGTLAPKYNDYIEHAYMTELKRSGHAEKLVNVDIAAGLDMLVQRGDWGKCLEKAATEGSDALNKYLLICCSNLIKESKYEQAVKYVVKHGVPANPNAFDTYIRITREVLHNGSNDGMALLREMLFKLVHGSTLLSQQGIPPNFNVYLMIAHLNTLKNYCSKKKELLYFGAKQSISLLRYIKDIPADKAFFEAGSAAKAAGMNNMAFVCWNRYLDMSEAIEEGDSSLLENADFEKTDVPYDVDLPPNNLPEAKREEVRDWILQVSLDQKINQELDHRDCEDCGTSIYDASLTCYNCSSKSEACVVTGYPVLRNKVKCTGCNRNANKEDWNKFVMIEKVNIACKHTNKSHTYSPGFITSTADKMLHNFHLFSEEEKEKIVLALISVAQPSTISKINKQLEKKLKIDFIGKLPIELSTYLLSFTDFITLGKIAQVNKYHKTVSEDNGVWRFLYKKNGWHINKLYLDNIISQNKDTSPTSICSSLISVKNYTITEVKEIDLEALDGDAITTGSLQRFVKTDDSKRVEHSIQSIENSSRNFGSENEQKCNLIDENSQLSEVSSVSKKASLSEISHQRKLLERNWKVGKYTMREFVGHKEAVYCLQFDDEKVVSGGRDKLIRIWNIKTGQVLNTLNGHLGSVLCLFYNNEYLISGSSDSKIIIWNFKTGALLKILEGHTESVTCLKIYESSIVSCSKDKSIKIWDFETGKRKFDYSAKIVLGRLMLTMLGHKVAVNSIEVKNGLVVSGSGDRTIKVWDFKTGKLIKTLMGHSRGVACIQFDGNLIASGSSDKSIKIWDLKTGKVLKTLSGHLDMVRTLQFQNNFLISGSYDTTIKVWDLNSGTNILTLSGGHPKKVFKLAFDCKRILSCSQDSKLICWDFGSGVEYKFFLGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1A8</accession>
    <name>A0AAD5U1A8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000454">
        <property type="protein sequence ID" value="KAJ3216909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1A8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="575" mass="66775" checksum="2D9258ECC627933D" modified="2024-05-29" version="1">MEKPHWIKYDQNIHKNKKKNLKMLGEPARTNNLTPKQRLRKFKDSKFQDNEDIHEDIPGRISNCLENLRMKDKKKLINLCNKLAAAELANEKIMSNLEFAATKNSDLEKQLDAIKLEAMEINKKYIEVVAKSEAEKHLLKNLKEKEELFDNSTKQQKIIEEYYQNFNSELSKLTCLTQKLEELNKRNILSEKKCTNDNAEEKKCNSPSPSFENNINISRYSENFDISNTSHLNHSSFDFLKNENISNNLLKKIIEKQNLLYADEKEILCDNEKPSKMFLKNKVKKILEISKRHSMQNENGTLFANQKILQMEHADKDFATSTTSSFKSDKIKIKKKTKRSKNKNIQCNRSEKYDFNHEVEDKSKNVQIKQGYLSNKQNENCNDLYNSSKHLHKKTNYTDEHFQHNHSHQQNYKSKEIKLNSKLIPHFICHLCTSGQLSNIHCTGVTNVKCNSVDKIDRSLEPNTVLPPKPHPKNDSFKYVNHGVVNFDEFEKSDLNNSSNKYMNNTNNLINRNKVDQSYLFLNESSMVKSLPDIVKELDDIIVDSGYNDPSRIDNVNIDNDLLDVISSLNGSAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1C4</accession>
    <name>A0AAD5U1C4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ATG2</name>
        <name evidence="12" type="ORF">HK099_003812</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000255">
        <property type="protein sequence ID" value="KAJ3221056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026849">
        <property type="entry name" value="ATG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13329">
        <property type="entry name" value="ATG2_CAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1814" mass="206564" checksum="9F7C75267800CC6C" modified="2024-05-29" version="1">MDFFTILQRKPLKFILKHLFGNYFENQIDIDYHSFSNGTILFKDLKLKKSLFNEILHDNQLHLHCANIGSLQITLNWRSLFYTSEKDSTSISIDIKDTTISVRKLDKFSDEYKDSKTYQNEKSKECGWISQNGYPCKRKIAIYKKACHFHIGRLLERSEALEKNLFLQDFESGATSQEELSVLLMKMLDKIISGLRATAYNTVIRFVHDSTYSFVKNTERKTQNHFHLDFNIPKMEYSAQNNPSETSEVGEESVYSLKLYGSQCTLSQLDTNLSYNVMNLQHSKPIISKENSSSSIYAFHSTLFANSSEIPQSLSVQFINKTSSASNGISNFFFLDAKVQMKNIVGFIVPVNPISNKPKINIDFSLESLNLLFCYQDLPPTETISKVYKLYFDMVDKGVKEGLTEVKLSPNFLPETLLYTQLNSNIDPSKFLDEIIAETLNFDHLKLGGEGLYGCVKQTTHGIDFSFYLNNLKISEWIKHLDNNCKKESLENLTEYIPVFRLKNENKSETKLVVEMYEKLKTKIFKPSHVRFIYEYKLKKELEEPRAKCIGCFNKNEKKSFIKFDFSEVNIFLDFGLINRLGNLLEYKNLVPHSDEEHLNYKENLDGSVIIDDLINHFSSTKISLDDSKVEYSVNCPLARVFIFCPNYESILENEIHDHYFIHKDIILIDVMKLELSSKLSSQSENREFFFKIGFNDVGFGVATPRNFTNSKTDVGGFKARSLWATKLDFNVIPIALIPSCEDMGSNIDIAIRNSKVFIDTALFKNHSGVKKSDEEIFTPNSTKSKSGDWLDVGNQTNDDEEFESIETFDEVEIRKNEGKDNDVIEKEKEKKEDKFNGFLKNYEKIVWLQRTINETAKQTKNEIMEKELNGEIKKDSKKEAELGNSEDLFTVFKSVPEMFEHKENEVSSDDDVEDFQSASGGSVFGLGSSIFQKTPLGVKFEQEQPYYSTYSYQQPKSPLSAISTGLNRDTSTSLGEKRDDVVIFNRFTISLFCDSVEGESSSSNTYQLNGDKFNTFLITYSQDLSSTSNLWLDFENVSITEVLTGTNFIEKTSCTSTPTVSLTYEVNHNLESFFRDATIGFYLNDSTIHYIPDSTISSHLTNFFSPPTLNYVDEMVTVLNVSVYGFDISLQHKFNKVPYNGILKFDKFKLSCNIVPESDSLDFKVNVSKFDLFVEEISSKNLSTATRIETDKDGNYLKIAVSNQKLYIDTCADSFDTILKLINSFAADELETCETETEATFPQQYVLHELIDVLGDMDEEAFRPRSPEAPFNLVHEDQSDAENSSSELFEEDYFAMPSKKINRNDLTPSQSKFLPTQDEIITVLDQSVRLVEDYLNSNLLNLNERHIQNNNQSSDILTSVRVCDFNVTWRIYDGFDWERNRDCMKRRELVNRPTFRGESGMPSTIKSNFHRSIEPKVEIRANMIKVEYDSFSADSVTSSRLLVLIKDFDIVDNVETSSWRKFLSFLTPSIGEQPRENGSNMINLELLNVRPDLKLNKEESRLKISILPLSLRIDQDTLSCLINFFTFDPTHGEINIEAIKKDSLQKKTKKDLFFQYILVEEIKLKIDYKPKHVDITSLSNGNFVEFMNFAMLTGASINLTEVQLSGVSGWSKISEALLAQWLPHMKLQVPQVISSISGLHSLVNIGGGLADLILLPVAQYKKDGKIIRGLRSGVESFASSTTMEAIKLTTKFAAGTQVFLEQADQLLSGGKKVESPSHFSKFSEQPSNLQEGVGMAYNSLKKNISTAANTVLAIPTEVYEKNNQGKVQAVIRAVPIAVLKPMIGTAEAVTKTLIGVQNSLDPSNKSLMEEKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1E3</accession>
    <name>A0AAD5U1E3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor BYE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003669</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negative regulator of transcription elongation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BYE1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000242">
        <property type="protein sequence ID" value="KAJ3221238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1E3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034088">
        <property type="term" value="P:maintenance of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21538">
        <property type="entry name" value="SPOC_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012921">
        <property type="entry name" value="SPOC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395:SF6">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07744">
        <property type="entry name" value="SPOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS central" evidence="10">
        <location>
            <begin position="187"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="614"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="618"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="669"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="684"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1165" mass="134227" checksum="9BD74E6FB947FF2B" modified="2024-05-29" version="1">MRQKQNGQNERGQKIYCLCRAVDDGNFMIMCETCSEWFHGDCVGITEEEGKEIETFECALCIDYQQNGGRNGESIEAKERIIYASDKLQTASEQSSRAKTRKGSDTVPSPIETKSNSLSTENLSTLCQDPCERDPVRRFSRKGFRETIETFFQEVLQFQMNKEEIKASLLDNDGQLEITAAKSESMIKDESLEWLESLDFNEIKVNLHDAEGYSSRMEDSLFKEFSEKNQLGNFECGPKYKSKFRSIQFNLKDKNNAKLRRRILYKDFEPEVLVTLTADQLANENIHSYAAQVRKQSYKSTVKPEGQDILIAKTHKGEVEIVLNKDVRVIQLDKTKSHQDMKLEEEKKILKQETLPFKKIESLDEILKGMNSYNEGKGVVEESSDGADCASPLLTGSPAMYLDSPPMDNYYLEEDKEQLDITMQLDEEDKNKLDGETIWEGKVSMPQVGKFNGTCQQVAGKKVGGVENWEDILPIGLNIDGRIPKKRVLEYLDQQKLSQSKEVVVLKFNPTVESQEDQVGYNTLFTYFKSRDKYAVIPHHYVSVKDMYIVPLGKDDELPEFLNWCDYKNKIFTIDDAEDEYKFLLEKNRKFDILLGVLVLHKNLVRREGEYNINESNNSHDLEKNKKRKEKEELSKKEKLERKKLRIDKDKSIFVSNSNSNSNQPSTSTDDKIQMKNISKDSPQDDGSFQNNVNNENSISTDNRTQENLQQQQQSLLNSLLRSGAGLNQFHISQQPSQQGLNFDFNLYNPQPLNNQHPFGVNSVDPALILNLLNQIQQGKNLEDYLLIELPVEFDIQNTKQLFIKGEKDDEAVICSDIDTFQIKQNFVSNSLLLTKKEVQPYDNEVVLSIKKILDSHLEVVKAKPRLHLIEKILEGSIYDGKSNEISINEDKHIIDFFEDEESMDTSSNSKGTKFYSLNDLIGIIQASEKEIVNRLDQISALNINGCYRIVSENHQEYLLKLIMNGLIINDCDISHFTFEDIKSVVNETDDEYEVVLHLILKNFCQPCDATHFRFSKRKVTRFFGKLLLANCENSFQHLNQPKKLSAFLTELEAAMPDTYFEVDLEHLKGLYFMEDEVISNIKCIRYFNKDDLVRRTFDNNEQISKKKRFADLFYNKAKWKLDEILPYIDDLVEGGAENRKGLNALLLKYARKSIVGKDEEYTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2U6</accession>
    <name>A0AAD5U2U6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,4-alpha-glucan-branching enzyme</fullName>
            <ecNumber evidence="4">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glycogen-branching enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GLC3</name>
        <name evidence="13" type="ORF">HK099_002256</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Glycogen-branching enzyme participates in the glycogen biosynthetic process along with glycogenin and glycogen synthase. Generates alpha-1,6-glucosidic branches from alpha-1,4-linked glucose chains, to increase solubility of the glycogen polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000173">
        <property type="protein sequence ID" value="KAJ3222502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2U6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11321">
        <property type="entry name" value="AmyAc_bac_euk_BE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02854">
        <property type="entry name" value="E_set_GBE_euk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000001">
        <property type="entry name" value="1,4-alpha-glucan branching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000250">
        <property type="entry name" value="1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000003">
        <property type="entry name" value="1,4-alpha-glucan-branching enzyme, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651:SF3">
        <property type="entry name" value="1,4-ALPHA-GLUCAN-BRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="12">
        <location>
            <begin position="193"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3222502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="674" mass="78083" checksum="BBC7CF46E31D96C6" modified="2024-05-29" version="1">MTKSLSVSQPLIDDDPYLTPFQPVIDQRIDKVNEWVHKINKYENGIDSFTKGYEKLGFTVKADGIYYKEWAPAVVEASLIGEFNNWNRETHKMKVNDFGVWEIFLPSVNNTPVIAHNTKVKISMVTRSGERIERIPAYIRRAVQDLSVSPVYEGVFWNPPQRHKFVNKSPKKPSSLIIYEAHVGIASPEGRVATYPEFIKNTLPRIAYLGYNTIQLMAIMEHPYYASFGYQVTNFFAPSSRYGTPEELKALVDAAHGYGITVLLDVVHSHSCKNVLDGLNMFDGSDHQYFHAGAKGRHELWDSRLFNYGNHEVMRFLLSNLRYWIEEYGFDGFRFDGVTSMLYTHHGIGTGFSGGYHEYFGHSVDDEALVYLMLANKIIKELHPNVITIAEDVSGMPTLCRKIDEGGIGFDYRLSMAVPDMWIKLLKEKDDSEWKMGDITFTLTNRRWKEPAIAYCESHDQALVGDKTLAFWLMDKEMYFNMSDLSPKTPIIERGMALHKMIRLISYALGGEGYLNFMGNEFGHPEWLDFPRAGNQSSFHYARRQYNLIDDDLLRYKYLNEFDRAMHLLHKDYKWCESPQYVSLKHEDDKLIAFERGNLLWIFNFHPHKSFTDYRIGTCWPGVIVLNSDDSKYFGHDRVSPTGEYFTSKGPWHDREFFIQVYIPSRTVLVLRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U331</accession>
    <name>A0AAD5U331_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA-processing protein EFG1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">rRNA-processing protein efg1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004538</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EFG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000322">
        <property type="protein sequence ID" value="KAJ3219892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U331"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019310">
        <property type="entry name" value="Efg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050786">
        <property type="entry name" value="EFG1_rRNA-proc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911:SF1">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10153">
        <property type="entry name" value="Efg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="48"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3219892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="213" mass="25117" checksum="6B74A2E0F09C3108" modified="2024-05-29" version="1">MPKSSKVRREKQLPVHELTASQLKKKERDTRRILAKQQKSERGNAAKKVELERRLEAITVQKETKKLQNTSKKLSEKYKYVKFVEQTKVERKIKQLEKKIKNKAEDNLQKNNNSSNEKEYEILKEYQKAILHLNYIKFFPSDLKYISILKLDNLTAKAKLLQDKIIEKVSFFMENKKTLHVFKKSDFIGVNKNDAATELEQEPVEAVEDDFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3C3</accession>
    <name>A0AAD5U3C3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000160">
        <property type="protein sequence ID" value="KAJ3222778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3C3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="513" mass="59679" checksum="E3B45439DF5330EB" modified="2024-05-29" version="1">MKLMNLRISIQNPVFIAFFFFVVIFFISVIKKSYINQTQHIHEIKEKYSTLNKKKNIFNKNFLLPDQKEFDDTVNNNNRIFYLEKYSKTSLLDFVEIGLIKEIHFNATKFVDQSNEFLPSASENSYISNSGTLVALSNHLTSNKQYYLHCSVVNYVTNSIIYDKFDVLLLNRLTIPLTFMHLTILDSNFQELPSDFEYQGQFYPKTIGINHDIGSIGPEDTRAIVDSDGNIIITFNMDDNEEFRLIWYYDLTSGVIRKLSHPFHKGPQSWVPFINQNDEVNFIYSWDPVIRPLRCGAEHPAKCFDYLVPKKSFSRNLDGLKRFQEKITLENENRTPGLSEFRGGSSLVKYKDFYVTLIRIRTANKAKPHQDPVFKVRLAILDPNLNLIYLSENLDFKGKLFLKPFFQFEDLNQFKLSCSHASILKSSALTQTTANDWVGEFSVNDQKNFVVVFKDLTLFIDAIIERYMDGGREPDQFNLLKDAVSEDKNSIQWCSDEEYNKFLKVGEMVKPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3F5</accession>
    <name>A0AAD5U3F5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="3">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NME1</name>
        <name evidence="13" type="ORF">HK099_004223</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000293">
        <property type="protein sequence ID" value="KAJ3220533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3F5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000002">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="12">
        <location>
            <begin position="109"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="9">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3220533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="571" mass="63534" checksum="0C96E0527C8F0BFC" modified="2024-05-29" version="1">MFKRVFTSAINKKFFSTSRSTIAENSNLKWKVLAVTSATLSAYLLTQNNTVYSDNRPKPWEKDFEKKAVSSHTSQTPPPKTDAFSSVGSGAVATNSVKTLNNSSVGKKRERTYIMIKPDGVARGLVGEIIARFEKKGYQLVGLKQMNASPELLKEHYSDLKNKPFFPRLIKYMNSGPVVCMIWEGNKAVKTGRKMLGETNPLESLPGTIRGDFCIEIGMNLCHGSDSVESAEHEIALWFPEGATEWNLARTTYTKSSSSDLDLLKRDSLPPHQVSADSSTLEILTNQVKEVEELTKRATFTLISNNILVFLSSSAAKYSAEWYCSTTVGDMLKSGGWNVIYAGFGQIASAIEKNKIVMYVQPGGNGDVNDLYKKFTSSDVNAIKKFVWNGGRICMGGFLATDLGLNMVGTSYYNEIKGYQNAMLVPATWKNNEIRNIFVKSAPQINSFNEVKGETKIYSRFTQNNYVNMFIKKFGNGYVGISAAHFEAVGDWVSKSQRNGFKKSWDIGLEFVNAILMRKLPKSFNLQHGNYGLSQPIAVHIFKEYGIRDKKIASQVSISKRFGHKQTGLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3G5</accession>
    <name>A0AAD5U3G5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Medium-chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_003540</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000231">
        <property type="protein sequence ID" value="KAJ3221418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3G5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000001">
        <property type="entry name" value="Acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000010">
        <property type="entry name" value="Medium-chain specific acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000011">
        <property type="entry name" value="Medium-chain specific acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016578">
        <property type="entry name" value="HsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="9">
        <location>
            <begin position="29"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="8">
        <location>
            <begin position="139"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="7">
        <location>
            <begin position="246"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="44547" checksum="745D74AAAE19E380" modified="2024-05-29" version="1">MFAIKCSPSLLRKATLANCKRFFSLELSSDQKQLKDLSEKFTLQEIIPKAAHHDRTGEYPTEILKKLHEVGLMNLHIPEKYGGAGMGVFDCAIVSEELSYGCSGIQTAAEANAPVIIAGNDAQKKKYLGRMVEEPLMCAYGVTEPVAGSDVAGIQTKAVKKGDSWVLSGQKMWITNSGHANWFFVLAKTSNDKPGKAFTGFIVDGNSPGITVGKKEINMGQRASDTRGVSFEDVVVPDENRLGQVGEGFKIAMGAFDVTRPLVGAGALGLARRALDEATKYSLERKTMGKHIADHQAISFMLADMAIGYEAAKGLVYKSAWLRDQNQRNTYWASIGKAFASEVANKNAADAVQIFGGNGFNSEYPVEKLMRDAKIFMIYEGTSQIQRSIISKLLIDSSKSGDPLYNKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3K6</accession>
    <name>A0AAD5U3K6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005631</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000449">
        <property type="protein sequence ID" value="KAJ3216991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3K6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="8">
        <location>
            <begin position="24"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3216991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="149" mass="15887" checksum="A7F277170F2120D2" modified="2024-05-29" version="1">MGALIIATATSTVVYDVADPNSLFKFCGNAETDGLGLRTVEMTPFPPVQGQNVTVTVNGHLKNVIQDGEKQALVNVKGQKGIFKIERQVLTCTPDSALPCPIQPTENLVQSYDYAVPTLPAFIKDIQLTVSGVNGDGSQLTCFTGKVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U412</accession>
    <name>A0AAD5U412_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Multidrug resistance-associated protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ABCC4_1</name>
        <name evidence="13" type="ORF">HK099_002942</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000200">
        <property type="protein sequence ID" value="KAJ3221938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000973">
        <property type="entry name" value="Multidrug resistance-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="762"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="800"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="885"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="993"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="114"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="453"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="765"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1084"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3221938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1338" mass="150538" checksum="968270BC8D35A896" modified="2024-05-29" version="1">MNKKKSDKAIQEIDLKKEEDESQFFKKQKYKAKKREDFTKASQFSFQYLNDLLKNGLKTKLDIDSFPEIDSFNMSNKLSGGIMKSWIKQKSDNKRKPSLLKAFLKVFGSDFYKASVCLLLETLLRIGQALIITLFLNFFSHPYNGSETTYAIGLGMALIITQVVIVTVHNVGFYILSKLGMQVRVSIIATIYEKLLSLNVSNTSSTGLIVNLMSNDVQRFEELCQVLCYLFIGPIELLLSVYFIYAQISYAAFVAVGLLFLLLPIQSFFSRIFTKLRGILVKFQDERVSSLSDMFSGIMIVKLYTWELPFCKQIQASREDEVRYLKKSAFAKSLNEAIFHSSSTLIASITFLSFFFLNGSLSPAQVFSTLTLLSNIRLSMTRFFPRCIQLGSECLISLRRIEDFLLLDDQTEKTVLISESTSTEKKIVQDLDEASDSNTESTFCNLKNASFNWKLNSFGKTVDEEDTIEILHNININIKSGNLYGVCGPVGCGKSSFAAALLGEMECKSGSFFRRKSIGNRKLKIAYSSQSAWIFSGSIRDNICYGSEFNQKWFDEVIKACAMEKDVYHFPDGVNTIVGGRGVTLSGGQRARIALARSVYSDADLYVLDDPLSAVDTKVGRHIFESCIQKLLMNVKYEGNYRRSPAAVVLITHQLQYIQLCDKVLVLNEGNVEAVGTFNQVIATSDKESSFTKKMKEFLDTEVEPEEPLLEDKSVDQITIASTLAASDDAIGRSELTIEDSSVGHVSLSTYLSFLTSGSSTILALLLLLYLVFGQFTVVFSSYWLSVWTNQNKVQQEQNYFYNVFILSGMVVLCLFINFTGAAAFFAVCLNSSKLMFDKMLSSVTRSPMDFFHQNPHGRLMNRFSKDINIVDEILPACFFDTLQLFLVLLGIFVMTAVIIPAILIIFPFLAGSLFYVRKYYINTSRQLRRYEAITRSPIYSEVPATLEGLSTIRAFATQKKSLFNFHKLLDYNTTMNFTFICITKWLSVRMDAVATLFLVVVVFSSILLKIYSNLSPGFCGLILTYSMQLVGLIQFAVRQSTEVENYMISAERVMEYTILPSEAAEVTELKPPENWPTQGNIRVHDYNLKYKGSDRKILDNISVDIAPGEKIGIVGRTGAGKSSFLQGLFRIVEPESGYIEIDDINTSLLGLKDLRSKISIIPQEPFCFKGTIRFNLDPFAVYSDEEIWKALDSVELKRAIEALPNKMESSVSEGGSNFSVGERQLICLARAILRNSRLIVMDEATSSIDLHTDSLIQNAIRTEFKHSTVLTIAHRLNTVIDYDKIIVLDYGKLVEFGSPAELLSKDSSSSDAWFKKMVEEMGEDAANTLIKIAFEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U455</accession>
    <name>A0AAD5U455_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">STI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_002500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000183">
        <property type="protein sequence ID" value="KAJ3222268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U455"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11713">
        <property type="entry name" value="GINS_A_psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000010">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000020">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000002">
        <property type="entry name" value="Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="4"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="10">
        <location>
            <begin position="134"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="245"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="320"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="10">
        <location>
            <begin position="517"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="196"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="207"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3222268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="662" mass="75152" checksum="45C41C14E672623D" modified="2024-05-29" version="1">MTTAEDYKSLGNKNFSAGEFEAAIENFTKAIELDQKNHVLYSNRSAAYASLKDYQKAFEDAEKTTTLKPDWAKGYSRKGSALHGLNKLEEAEKAYSEGLKLEPTNALLKKGLEDVQAASRQSSLPNNPFANIFSHDVFSKIASNPKLAPYLADADLVNKVKMCQQNPQLVSSYMSDPKMMQLIVGLLGIDASAFGGEDDKMDVDPTPPEKPKDTPAPTPKKEEPKVPEPELSPEEKEKKEKRTASDKEKEIGTGFYKQRKFDEALEHYNKAFELDQSNVAVLTNKSAVLFELEKWEECIKVCEKAVEIGREIFADFKIMARAYARMGNAFAKLKDYGSAVKFLEKSLSEQRTPDVLTKLREYEKLKKLADEEAYTDPKLADEAREKGNELFKKQNYPEAMTYYNEAIKRNNKDAKNYSNRAACYMKLMALPEADKDCDMALKLDPKFVKAYIRKAAILYTKKEYLQAIDVCNEGKVADVEKKHTQELDNQIHRCYAGINQNQSGENKEETMKRAMENPEVQQILGDPVMQSILQQMQTDPKAAQDGLVDMKEPSCFSQKVRDDLDASYIAVNLHSLCPNFYTFGAKMLNLIDDDELLNNLITTYKSRLLTISDYTQTSKLIIDRFTFVDSLDESEKDVYKKGYESEISIRNWMKKTTANKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U478</accession>
    <name>A0AAD5U478_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rhizopuspepsin</fullName>
            <ecNumber evidence="3">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PGA5</name>
        <name evidence="12" type="ORF">HK099_003667</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000241">
        <property type="protein sequence ID" value="KAJ3221259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U478"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase A1" evidence="11">
        <location>
            <begin position="65"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="301"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="374" mass="41200" checksum="6E7C676575023BC7" modified="2024-05-29" version="1">MFTIQLSKLKKSHSGISNIKKGLTLGKKYKQHNKKFHLNSQRRRGNLLQKRQTDIPLQNGENLEYSAEVSIGTPPQTFHLVMDTGSANLWIASTDGLTSNNFISSQSTTFEEEDSKPWTIQYGSGNASGIFGADIISIGGLQIKSTIGLATQLSEGFFSSNDDVSGIFGLGFSSMAAGKVLPPFYELFDQGLITQNLFGCYLGNDVRSNIDNFGGEITFGGIDTSRFTGEVYYSPLSSENSWQINLQGINVNNNLIPLIATDVLFDTGTSLIALGTSDFNTINEIIEAKFDINNSVFKVDCKKIPELPNFAFIINGYQYTLTPNQYITILEGEICISGFADLGMESSFIILGDVFLMSHYTVFDFEWVSQILVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4H9</accession>
    <name>A0AAD5U4H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin fusion degradation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UFD1</name>
        <name evidence="6" type="ORF">HK099_004904</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000361">
        <property type="protein sequence ID" value="KAJ3218880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4H9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="4">
        <location>
            <begin position="13"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="5">
        <location>
            <begin position="116"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="308" mass="34489" checksum="E720CEA8240753A3" modified="2024-05-29" version="1">MFHQFMGVQNNRFEKTYRCYSILCMQGNPKVLDIQNGGKIFLPPSALLAIQSMQVQFPLTFHLSNHKETNLKSTHAGVLEFNAEEGRVYVPQWLMVQLMLNEGDLIKVKYSALPLGTYVKIQAQSVDFLEIHDHRAVLEKAFRNYGTLTEGDIITINYNNRTYDILVMETKPKGAISIVETDLQTEFAAPLGYQEPTPIPKKLTKPSLEGSVENITQHVVKEEEGFSAFHGSGQKLSGKKLGEEIIRKKEYSKNKPPPALVLPAGRIFFGYKVVPLKGNESAEGSKENIFSGEGKTLRASRKGKGKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U576</accession>
    <name>A0AAD5U576_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_001299</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000135">
        <property type="protein sequence ID" value="KAJ3223325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U576"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015108">
        <property type="term" value="F:chloride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051280">
        <property type="entry name" value="Cl-channel/antiporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11689">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0129">CBS domain</keyword>
    <keyword evidence="9" id="KW-0868">Chloride</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="587"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="803" mass="90481" checksum="90E3EDA75EC5D29A" modified="2024-05-29" version="1">MTTILSSNYTQINKMDDSKNIIKRKKAKEKVLETVESALYQVDDTKNYREKIKFMKNKHVIYSKILDWFVTSLIAITVAFVGLAVQFTPMAHIGAAIGYLINQLLKKPRRKLENDPNYHPTRSGGKSMEADDRDAVAAGAGCGLTVIFNAPIGGSLFYVEETGSFLNISTIRRNFYSCFLTYGLVVYLQISNGTFSFLSEKPANPFCNERQIKTLDLFMFALIGILGGILGSLFNKCIKYTSKINWDNFGVYYVYLKLKKFYYKDPQPVKTNPAKLKWRRIEFTLILAILVSSTRVFLPLLFSCKNLDSDLFLLEQPSLCLGISHEKLMFSGISYLGNAQHNTSSIFNNHQDCKKFSRLNSVQSLQKLSWGYQEVEDEEDVLMIVPQYAIPTKPGITLDRVLPIPLPNAYPQKSGKSIPVDISTAVRYNCPAGQGGTQMPALVLGAVFGRMMGFIGTYISNKYCSNWLFLPPVLISEAERLAGLNSSQDCLKLCATASDPLLYAIVGAASMLGGVNRSPLYCAVVVSELFNDLDSLPSIAIGVFISVSVGNFFNRGLNHTLIDSKIPLYLNEEAPLNFESREISSVMTKEVICIKNFVQLSEIITILEDQSIKNLNAFPVYKEETDTKNGNKIFVGLVYRKKLDRLIKSLLKAEKVEEVAPTDVDFDKLEKNFNEKEIFLQQVNLDSEEDLDKLGFPEIGKLIKSNKIEDLEEEKVIKSENIASVDCENKVNKSYISLNLNVHVDLTNYMELSQFCVLETFSLGKAYRYFRTLGLRYIVVVDSFYCIKGIVTRKDLNSYKLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5M2</accession>
    <name>A0AAD5U5M2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_002440</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000180">
        <property type="protein sequence ID" value="KAJ3222338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18660">
        <property type="entry name" value="CD1_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18659">
        <property type="entry name" value="CD2_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056302">
        <property type="entry name" value="CHD1-2/Hrp3_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025260">
        <property type="entry name" value="CHD1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF14">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13907">
        <property type="entry name" value="CHD1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23588">
        <property type="entry name" value="HTH_CHD1_Hrp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01176">
        <property type="entry name" value="DUF4208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="14">
        <location>
            <begin position="236"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="14">
        <location>
            <begin position="324"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="437"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="738"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="60"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="168"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="931"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1002"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1308"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1451"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="103"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1015"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1049"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1470"/>
            <end position="1481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3222338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1481" mass="169811" checksum="00647485F79C92D4" modified="2024-05-29" version="1">MDFPSPTPLSNTNSPSIDANKKILSASINKKTNNENSEVTELPNTTIKIPMLSNKINSNLKQDQNYLNVEDSEQEEESNSEQGDEEDDSFVPKKSKYPKQPLSDDEDQYDDNEYPSDEQYNDQDPSDFDDDVDNSDESEYGSRKKKSKYKAKKKFNVIKVKKIKKVKFSSENDSSDSEQDYRPSMDDMSVSNYVNPHNRNDGLNYDESLIDEMLGLNDEENVIEYIYENADEPEADAIEIIIDNKKEGNDVKFLIKWKNKSHIHNTWEIAADLKGIKGYRKLENYQKKMQQEEEYRQQSDISKEEIEHLDINKEIERQTYEDYTKVERIVSVRECVSSIEDDDDEDTFNNSAKLEYFVKWKNLSYENCTWEPSHLLSNEYQNEIDSLLDRNSSEKVPHKSASVTKHRPVFKPFSVQPKYMKGGTLRSYQLEGVNWMAYLWHQNDNGILADEMGLGKTIQTISFLQYLFNTINLYGPFLVVVPLSTLSNWAREFNKWAPEINMLVYNGNGASRSVIREHEFYFEGTEKLKFNALLTTFELILKDKDELGQIKWMYLAVDEAHRLKNSESQLHEALKDFYTQNRLLITGTPLQNSIKELLSLTQFLMPDKFSEFEGFEIGVDNNEDEVQAENISKLQAKLKGYMLRRLKTDVEKSLPQKTERILRIELSPMQLTYYKNIYTKNFAQLNKSGGEKVSLMNIAMKLRMCSNHPYLFPNAEPLTKNKEERLRGLIMNSGKMVLLDKLLERLKADGNRVLIFSQFVMMLDVLTDYLIMKGYVFQRLDGSTGSDARKRSMEHFNAPDSTDFCFLLSTKAGGLGLNLETADTVIIFDSDWNPQNDLQAMARAHRIGQKKTVNIYRFVSKNTIEEEIIERAKRKMVIEYCIIKQMDTTGESMIYKNKKSKIDASGKLSREELELVLKFGAQNLFKQHDEENAAAAAASNEEDGSGAVPKNKLEEFNLDDILARAEHSDQIIEQAGGASDGGAAFVEQWKVADVGVGQMSWGEIIPESEQPKLSLSDEEKQLKEEYGGRKRTATMTYANEGRQDDEGRRKRKKVSTSLRKKRKSNDGNSPLDEKELRSLYTAMTKFGHPRLRLQQVIEDAELDGVEKEIILSAADKMIDVAYEAVSKGISSGSEKNGKLSESKKKEVEKYCSTFSVKTKVLYGDIYDFKQFNAVKLVCHVNLLKALTNRFDASTTEQQFKSFRISSKIKPVRQWGCSWGPKDDSLLMVGLFKHGLGIQSWEMIKNDPILGFKHKFNLDKKSGGGKEEDEGKDDKSTLPGTLHLYRRALSVLKVLCEDDELRDGLHKLNKRKKAKKDDSGSEEIFVRKPTKRQTMNSRESADMKSLPTFSNIKKRTSSNSKATEINGERVRELLEPIIENLRNLKDSLSSNSPTVALKENLFKVGDRVMFCCSEEKDSALEKKLWKYVKDFWPSQNVSWEQIRDIYIKFQDASGKDSKASSTTNLGVTGNDLKKEKEMKSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5N4</accession>
    <name>A0AAD5U5N4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007077</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000066">
        <property type="protein sequence ID" value="KAJ3225251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5N4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45926">
        <property type="entry name" value="OSJNBA0053K19.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Bromo" evidence="8">
        <location>
            <begin position="68"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="9">
        <location>
            <begin position="261"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="10">
        <location>
            <begin position="454"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3225251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="557" mass="64064" checksum="C4BA57BB504AC970" modified="2024-05-29" version="1">MILPNSPTSNNVTDSYLMSNSLSDQSSEVTNLYHPQSPPPSPIPYTKINHITPTVISKLKKLEQSTLKNLNFKTYFFNPVDPIGLDIPDYFEIIKNPICFKEITQSLNDNVYKVLNDYTDDINLMFSNSFLYNKNDPYFMDLAKLLYQEFISQFNLLFPDVYFYNLLMDEKRVKKREIRLSKFKNSDDEIDIDEKKWSLAKNKKRKYSKGKSMNINAAFKFENKKIKVNIEKATIKKTFLEKNKEIAKNSTIEEIPNAKVCHFCSTADTPMWRRGENNVILCNKCGVRWRSGKLGKLKKNVSKIETKMKNIKMNNSMDHSKPDNSIEKYENSSQNKEKLEKNLKRGEIKLKNNQNAVLNPFVETIIFNAQEEASSIDEMKKLQLLPQQFNISDLSFNPIPFDSIATKNTSNFSSFPDGDGISNSNVCGPYNFFVATPQVLPLLNINSLDINYNFSDIYNFGADLTIEEKLILSTKINLILKNKNEHKLEGIIKILKNNSASLNKKDDELIFDLNQLNSKTCFELKSFVESFDLEETNDEQVAVSCSDDEISGCESDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5V3</accession>
    <name>A0AAD5U5V3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Adenylate kinase isoenzyme 6 homolog</fullName>
            <shortName evidence="10">AK6</shortName>
            <ecNumber evidence="10">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Dual activity adenylate kinase/ATPase</fullName>
            <shortName evidence="10">AK/ATPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003781</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts with small ribosomal subunit protein uS11. Not a structural component of 43S pre-ribosomes, but transiently interacts with them by binding to uS11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate kinase family. AK6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010000251">
        <property type="protein sequence ID" value="KAJ3221109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5V3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000372">
        <property type="entry name" value="Adenylate kinase isoenzyme 6 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00039">
        <property type="entry name" value="Adenylate_kinase_AK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020618">
        <property type="entry name" value="Adenyl_kinase_AK6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595:SF0">
        <property type="entry name" value="ADENYLATE KINASE ISOENZYME 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595">
        <property type="entry name" value="POS9-ACTIVATING FACTOR FAP7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13238">
        <property type="entry name" value="AAA_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMPbind" evidence="10">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="10">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="175" mass="20289" checksum="ADDD402B667EA4A2" modified="2024-05-29" version="1">MTTRKLPNILITGTPGTGKTTTAELAADACTLKHIEVGKLVKELDLHDGYDKDFDSYYINEDKVCDELELLLKDGGCIVDYHGCDFFPERWFDLVVVLQTDNSVLYPRLQNRGYTDKKINENMECEIMQVIVEEARESYKEEIIVMLKSETVDDMESNVERLMEWCENWKTNNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U676</accession>
    <name>A0AAD5U676_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoribosylformylglycinamidine synthase</fullName>
            <ecNumber evidence="3">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Formylglycinamide ribonucleotide amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Formylglycinamide ribotide amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_003449</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000226">
        <property type="protein sequence ID" value="KAJ3221504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02204">
        <property type="entry name" value="PurL_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000002">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.10:FF:000005">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.650.10:FF:000024">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.750">
        <property type="entry name" value="Phosphoribosylformylglycinamidine synthase, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055181">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01735">
        <property type="entry name" value="FGAM_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003672">
        <property type="entry name" value="PRK05297.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10099:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22689">
        <property type="entry name" value="FGAR-AT_PurM_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13507">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01211">
        <property type="entry name" value="GATase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109736">
        <property type="entry name" value="FGAM synthase PurL, linker domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="PurS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase N-terminal" evidence="15">
        <location>
            <begin position="87"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosylformylglycinamidine synthase linker" evidence="14">
        <location>
            <begin position="263"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="13">
        <location>
            <begin position="535"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT PurM N-terminal-like" evidence="16">
        <location>
            <begin position="737"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="13">
        <location>
            <begin position="922"/>
            <end position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3221504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1415" mass="155458" checksum="CBC0840329AE142D" modified="2024-05-29" version="1">MFGIGRVSVTAVAADAADYGYRKSYRRPLKTYISTPQTSYQKNSAPNPFGYKFLTLLLGSKALTSFKQKSLLANIGDNNITHIDALYTHFVGSDFELDKTVLSQLDTLLKYGDFHNNDDLEYIKFYLKSYLSNDNSENNILKFDPLIKVLLVVPREGTITPWSSKATDIAKICGLSDSINRIERGLAYIIKSKTEITDISTIKNFLHDKMTQEVLIEVKNLDKLFSTGPPRSLKSVELLEEFNSSKKMGKSLENCFNDAKLVLEKANSDWGLALADDEIDYLVKAFLSNEDSPRNPTDVELMMFAQVNSEHCRHKIFGATWTINGSDQADSLFGMIKNTFKLHPQHILSAYSDNAAVLNGATALRFASGPESNFAYKTVLEEVHTVAKVETHNHPTAVSPFPGAATGSGGEIRDEGAVGQGSKPKAGLTGFTVSNLNIPGYIQPWEKNLENVGYPAHVAKSLDIMIQAPLGGAAFNNEFGRPNLCGYFRTYLENVPDHNGKESLRGYHKPIMIAGGVGSVRPMHVFKKKITPDWLGGGAASSMASGSSSAELDFASVQRDNPEMERRCQQVIDACTSLGNKNPIVAIHDVGAGGLSNALPELVHDSSLGGRFQLRDVPCDDPAMSPMEIWCNESQERYVLAVLPEDLKLFSSLAKRERCPFAIVGVATAEERLVLEDSLFNSRPIDLPMNTLFGKPPKMHRNTVTAENTLKPFSIPQSNLSIKDIADRVLRLPSVGSKSFLITIGDRTVTGLVARDQMVGPWQVPVADVSVVNLSYEGFNAQSMAMGERPILALINPAASARMAVAESLTNLAAADVPDLKTVRLSANWMSAANHDGEGAELYEAVTAVGLDLCPKLGLTIPVGKDSMSMKSKWKDSNGFEKTVTSPLSLIITAYGPVVDSRRTFTPVVEGGSALIFIDLGAGNKRMGGSAIAQVFNQVGNETPDVEVESFKAFWASLQALRSKNLVKAYHDRSDGGLFVTILEMLLAGHTGAVLDISHLGGVEFLFNEELGAVIEVSNEDLQEVTATFESHHFNCKHLHNFGKVKNKFEKDNEFLVILEEKITSLHQIWSETSFEIQKLRDNPILAKNEFDLLRDFSNPGLDEFLTFEMDEDEPLIIKQLKDKSIKPKVAILREQGVNGHVELAYAFHAAGFDTTDVHMSELIEGTVRLSNSDFRGLACPGGFSYGDVFGAGNGWAKSILMHEEVGRDVKLFFDRGDTFVIGGTTFLCYSLYKTNILVCNGCQMLSAISILIPGVGNVSTGKPKTKWPKFTYNASSQYESRLSLVKVLPSPCIFLKGMNGTIAPIAVAHGEGKTKFEDSDAELNMMELACIQYTTPAGEIASEENYPYNPNGSKNGLTGFTSPCGRFLAMMPHPERVILDVANTWKKSNRSRFGPWMKMFWNAREWCEENVIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6L3</accession>
    <name>A0AAD5U6L3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000044">
        <property type="protein sequence ID" value="KAJ3226103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6L3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16461">
        <property type="entry name" value="RING-H2_EL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46225">
        <property type="entry name" value="C3H4 TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46225:SF19">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="387"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="613"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="661" mass="73837" checksum="53C927A7CFC81375" modified="2024-05-29" version="1">MDASKPAIAPKPSKKAILEAKYNSKQNTSIYSNFQNNSNSNSYSITFDNNGDVPPQIAPKPKLYPKKSEFESDTLKDEKVIAPVKPERNRSVSNLPRSNSEKRPNPPPKPVRKPTLNLTSSGSFNSIMMQQKSGDELYNPATSSLTTSAPPLISKTSTNFIPNINLTQGSGNAIHEGKKYVYPPPRSNAVDIYNSETDRLSTGAVPMAPALMVNNPLTARVRRNWVSYFILNFGAISRGSKLILFLNLALTISQLASGITILILEWDAVCDQPLKKFLVVYLIRVFLAFPLVSYEHLQPEHQSLLDTNHRHRRNQTQTATSTDASNNIPENQHSVNISLGNRAAMSMISPWLNRLKITLDIFGTVWFVIGNYWLFTSTNCSVPLRYLSLVFVVLGYFVLLIPIIICGAVVFCLPCVLVGMRWLRVDYNTKGGQHLGASPDDIKDIPVFFYRKKGSSVALSPRQSQDINGRTLEVEKHHNLQAISTANNTNNISNTVSLTLTVPSPPPKPNKPSRIHAEAFDNSIELNEIVVANNNNNSNNWRGTSRRISISRVNSTQTQPNNSIPFNTIPISTSSLSSVTSSTNNNNANYSIEMNSVESENYEIELDDDDAVCVICLNRYIDKESLRRLYCMHHFHKKCVDEWLRMNKTCPLCVRSITNFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6L4</accession>
    <name>A0AAD5U6L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="16">1.3.8.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">2-methyl branched chain acyl-CoA dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">2-methylbutyryl-coenzyme A dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ORF">HK099_005145</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="31" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="31">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>(2R)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = ethylacryloyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65296"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156439"/>
            <dbReference type="ChEBI" id="CHEBI:156440"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:65297"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>(2S)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48256"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:88166"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:48257"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57336"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:43781"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:44180"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62500"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:44181"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24004"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:24005"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>hexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43464"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:43465"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>valproyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65344"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156457"/>
            <dbReference type="ChEBI" id="CHEBI:156458"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:65345"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 27">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid degradation; L-isoleucine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; mitochondrial fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 27">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="31">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.5" evidence="16"/>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6L4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003853">
        <property type="term" value="F:short-chain 2-methyl fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046395">
        <property type="term" value="P:carboxylic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01158">
        <property type="entry name" value="SCAD_SBCAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000012">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000001">
        <property type="entry name" value="Acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF1">
        <property type="entry name" value="SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8 27" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 27" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12 27" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="30">
        <location>
            <begin position="42"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="29">
        <location>
            <begin position="165"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="28">
        <location>
            <begin position="271"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00039850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00049096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00049552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00051903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="KAJ3226314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="505" mass="56189" checksum="E78580ACBBC572C4" modified="2024-05-29" version="1">MLFSKIKCNSLRSFSINQSKRLFTSSALQRSESKIASLHTFTEEEQMLRESVAKFAKEVVRPKVFEMDEKELLDKSVLSGLFNQGLMGIETPTDYNGSESSFTSAEVTICQLAIIAVEELAKVDPSVSVVCDVQNTLVNTLFRKYGTDAQKEKYLSKLATDTVGCFCLSEAGAGTDAFALTTKAEKKGDYYVLNGSKMWITNSYESDIFLVFANIDPSKGYKGITCFIAEKDMGVKIGKKEIKLGIRASSTCVVNFDEVKIPAANVLGEIGQGYKYAIEILNEGRIGIAAQMLGLAQGVFDETMPYLYERKCFGQHIGDFQGMQFQVAQVALDIEAARLLTYNAARLKEEGKTFVKEAAMAKLYASQVAERSASKCIEWMGGVGFTREYPVEKYFRDCKIGAIYEGTSNIQLQTIAKLLKPFTCTHLSLYLCTKTDEHFPHYPHLDSSSPKSLTVSDDNLDKPIKSSYIHLTSVYETFLSRYSSNKAKFAPCIYSKQDSLHFIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Q7</accession>
    <name>A0AAD5U6Q7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000040">
        <property type="protein sequence ID" value="KAJ3226261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Q7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027973">
        <property type="entry name" value="FSAF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053030">
        <property type="entry name" value="Ribosomal_biogenesis_FAF1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096:SF1">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15375">
        <property type="entry name" value="FSAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="329" mass="37543" checksum="591FCC771F490A2F" modified="2024-05-29" version="1">MSAILESKLESMLKSQFDFDSIDFTSEVKKTKNSKKKEKKDTLKRKRKLNEAEKLDLDESTKVEKNKDMEEIFKKTQNSTSKCKNEAGANQNKKDSKKNTVQVVVHTDFKAQNNTPGNISSNFRNFMSSKIKNVSGTKQKRQKLDDEDETEKEDRKNDRELKEMIANSKLIEEYTASELYGKDRRLYLKNKLAELGGRPETSHAKKAPTRIRLGMEKKILEDAKKKLQEAKDMGLYHEKTKHIYSDEVLKKGKGNIKRKSWGEGGLKQNFGTFSNGVLKISKKEIEMNTSKRGGSKGKKGEMGNKALRAIGIGTIKKNKVKKGGKNKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U721</accession>
    <name>A0AAD5U721_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">inosine/xanthosine triphosphatase</fullName>
            <ecNumber evidence="9">3.6.1.73</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_003968</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ITP + H2O = IDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28330"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58280"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.73"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>XTP + H2O = XDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28406"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59884"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.73"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.73" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U721"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103023">
        <property type="term" value="F:ITPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.950.10:FF:000002">
        <property type="entry name" value="Inosine/xanthosine triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00648">
        <property type="entry name" value="Non_canon_purine_NTPase_YjjX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002786">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026533">
        <property type="entry name" value="NTPase/PRRC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050299">
        <property type="entry name" value="YjjX_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00258">
        <property type="entry name" value="inosine/xanthosine triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34699">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34699:SF2">
        <property type="entry name" value="NON-CANONICAL PURINE NTP PHOSPHATASE_PRRC1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01931">
        <property type="entry name" value="NTPase_I-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-canonical purine NTP phosphatase/PRRC1" evidence="12">
        <location>
            <begin position="12"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3226856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="183" mass="19894" checksum="9418190457371830" modified="2024-05-29" version="1">MTEKKHLLVVLGSTNPSKILSVKNSLEKIMKNYSLEVIGVKAPSGVRDQPMSDEETLKGAENRAKSVLAQYPHADFAMGIEGGISKIGDVFLENGFVVVLSKNGEKGIGTSGSYQLSSKILNKINEGTELGDIVDELSGEESVKTKQGAMGLLTKNLITRDKAYETGIIFAFSKFYSDSVYWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U728</accession>
    <name>A0AAD5U728_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000176">
        <property type="protein sequence ID" value="KAJ3222415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U728"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21669">
        <property type="entry name" value="SMP_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="6">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="171" mass="19811" checksum="ADAAA7B18B1022A4" modified="2024-05-29" version="1" fragment="single">SDLAVVDIDFGEESPRIDNVRIIKQITDDMAIEIEMDFVYAANAFFSMDVQIFRGKCYKSIVTLTHIKGKLRIRLPSHKSPYKIDLTFKNNEDEKVCKFKVDVDSEKSSLVEESINRILSKIFKKLFQEKLVYPNVFSFNLPVLSKNLQKKTKEDLKDILKPEFNAVALEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U761</accession>
    <name>A0AAD5U761_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UTP11-like, U3 small nucleolar ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UTP11L</name>
        <name evidence="7" type="ORF">HK099_003982</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U761"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015952">
        <property type="entry name" value="U3snoRNP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3226870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="274" mass="32809" checksum="40CE30578F0A6405" modified="2024-05-29" version="1" fragment="single">NVVKKRKYKERSQLSSRSHLGLLEKKSDYKLRAKDFHKKQDTLKQLKEKATNRNPDEFYFEMINSKSVNGVHVKERKNNIDNDFLKLLRTQDKGYISLQRSVNLKKVEKFKETVHFLDREEEKEDAELEIIDSNSEDDGSFSGKEIVKNETKTKEVSHTIFVDDERQVEKFNPSQYFQTPESLISRKFNRPKFEQIKDFKLPKHITKEDLEYNQRLKEKKVIEINKRLHREAKLKKVQEEIELQKNLMGKGQRRKIGVKPDGTPLYKWRNERKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7F2</accession>
    <name>A0AAD5U7F2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial</fullName>
            <ecNumber evidence="13">7.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NDH51</name>
        <name evidence="15" type="ORF">HK099_006857</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Complex I is composed of about 40 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Mitochondrion inner membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
            <orientation evidence="13">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.2" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000062">
        <property type="protein sequence ID" value="KAJ3225399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7F2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.230:FF:000001">
        <property type="entry name" value="Mitochondrial NADH dehydrogenase flavoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.600:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11540:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050837">
        <property type="entry name" value="ComplexI_51kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011537">
        <property type="entry name" value="NADH-UbQ_OxRdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054765">
        <property type="entry name" value="SLBB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01959">
        <property type="entry name" value="nuoF_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010120">
        <property type="entry name" value="PRK13596.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11780">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22461">
        <property type="entry name" value="SLBB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="Nqo1 FMN-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142984">
        <property type="entry name" value="Nqo1 middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="Nqo1C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 13" id="KW-0288">FMN</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 51kDa subunit iron-sulphur binding" evidence="14">
        <location>
            <begin position="362"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00063883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3225399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="466" mass="51105" checksum="9532DED8E8AB9809" modified="2024-05-29" version="1">MLKSSLTSMKISQNLRSFGTAADPVRRNYGNLSDNDRIFTNLYGKYEFGLKGALKRGDWYKTKEIVLKGQDWIIKEIKASGLRGRGGAGFPTGLKWSFMNKPGVDPRPKYLVINADEGEPGTCKDREIMRHDPHKLVEGCLVAGRAMGACAAYIYIRGEFYNEASNLQVAINEAYKNNLIGKNACGSGYDFDVYIHRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGLFGCPTTVANVETVAVAPTICRRSGAWFAGLGRTRNEGTKLFCISGHVNNPCTVEEEMSIPLKELIEKHAGGVKGGWDNLLGVIPGGSSVPVLPKHICDDVLMDFDALKDVQSGLGTAGLIVMDKSFDIVKGISRLSAFYKHESCGQCTPCREGTTWLDNMMRRMVNGNARKPEIDMMDELTRQIEGHTICALGDAAAWPVQGLVRHFRPELERRIDAFQQNSGSKNEKESVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7I2</accession>
    <name>A0AAD5U7I2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 8">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1 8">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MPK1_3</name>
        <name evidence="11" type="ORF">HK099_002433</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1 8"/>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7I2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07834">
        <property type="entry name" value="STKc_MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018624">
        <property type="entry name" value="Sec66"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09802">
        <property type="entry name" value="Sec66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="524"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="528"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="540"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="574"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="591" mass="67365" checksum="13FB08A6AFD3E49E" modified="2024-05-29" version="1">MSNKSKTPEVNAPSILKKYSFKKEIGQGSYGTVWSAVDIKNQNEVAIKKVGARNFEEGILAKRALRELKLVMHLHGNENVASFVDVEINDPNNFCELYLVEGLMEADLNQIVKSNQPLTDQHYQYFLYQLLRGLKWIHSANVLHRDLKPGNLLVNSDCELRICDFGLARGMGTPQFVNTEYVATRYYRAPEVVLNPTNYSKAIDMWSVGCIFGELLNGKIMFKGKDYVDQLQKIFEVLGTPEDLLLGTLCSQRVLKYIQGWPKKSKQNFSKLFPNAEPLALDLLSKLLEFNPQKRLSAEEALAHPYLAAYHHEQDEPSHPQHFDFGFEKAQKISDIKKIIVDTVKEHKMMSANRSQPCSPTKKKPEPLLANSEEFHQIPRFDTEEGVRVAGSIEEELLKMNDLKVSEHLSKDIYLELSEQYSPEDVDGKKLLCAALLKRAVEDVRRIIKIKDEKGPLSQLVKSGCVGEDLLENIVAAEEELNLECEEVVFEADLLKPGWKNTIFQEASQIAQNQIQKEKEKALKTLESDDSSEDEENEESDKKNKNSKDTQDANEAERLKLERELLEEEEKENKSKKSSIKKPGKKPNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7L3</accession>
    <name>A0AAD5U7L3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000104">
        <property type="protein sequence ID" value="KAJ3224121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7L3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="71" mass="8351" checksum="1B990B68F5D6555E" modified="2024-05-29" version="1">MYFRKKPTFNIYLTVHLIRIYSVFVDKDDLEGHKFLIETSVAASYNKVDTILKDTTLSHSFTSDLMIFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7S4</accession>
    <name>A0AAD5U7S4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000146">
        <property type="protein sequence ID" value="KAJ3223047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7S4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1190" mass="135527" checksum="8ADCA3FA07F73125" modified="2024-05-29" version="1">MDIQCSLNYLRDASLHVPKVYGAASIKRIFENTVLWKFTEVFKLRFHCGDLRMLAGECYALDTSKDFERLHIPTQDVLNASANCTTEQLSPSSFETSNQHSSFFQVSTQSESPHVKLKIDVKDQLKNEEKKVKKSWSLQNFKNPLLYTENTKSKKLKKKFSLNLKNSILEQQQKLFEISNPIGVRSTLIRPKNNINTDSSDFPILLNLNFLDKEADFTENRQNSNPEITSDFDSFSRKTRNSNRNGFIDLQCRDDFSNYSSHTSNNSQYIPNENLQSDFNNCLSDESFQNSSVINRCSYEDGQAEVFSSVFLTGDDRVFLDHSKNSFNNSTSRYLTGSADEFEKPQNSNHIQFFNQNTDKNYDVDIVTDEANALNLTDRVFTLEKSVTLKSVQPNQIMSPITSLASNATSPLLETSSINTDSSYSDVIDVTVTKGLKSLRTVKSAVWSSRSDMHHPTPAITPEPASPNHFYPLLNICDGNVKTNDVRKNVTCADDKKNFSGDILHNKPSIVSPISQSKIQLDDSLDEVSTVTNSERNDFDHYNALEVLNTLIEDSENILRNEQDGSIDNFSDEKSSLSSSFLSKNDRYLKKDMVEVNVRKGECDRDYDLELKRHTNTTSDNEKKNMWKLLKAKLPFGAKVQNTQKLPKRSSFSLPNNFEDTNDVQEKVNKNLKFLEDSSPSLLDKETSHVKINYTSESDLIDDYEYPVSYSFNRSNTVGINRVLTGRSSIIHNWEFPVEEKIKNQNVAVDRTAEPFGSVNFIKSEAGVASTSSAKDETASANPSSPIFVAVDDNSHYDVVGNGRRSRNDSENLFSELQPPALNSQLHHSLYERSDFQIKENSNSNFLSHLPFPLPATRSKKTLKNYGSSTPPLFNNEMAQISHNPNENNFNIQYQPQQAYVQHIINNQHRSRTDFIHPHQQNFNNGPQYDITPVEPLYQINNQIQQLGKQIPSRQSVVDGQRRQRHQITQNENIRINKSFHTPIPLFPNRPSASPFFGNRNNDQPFNLQQQPFRENQKINNIDGLPKKIDWKSFNEKRHQTSSPDNSSQYSAVSLPGGCDRIASPNQSTTTVTPSVGSGEHYHLYQNNNENKIVYNGDSYYQKEEEENIEQIDKSLVMEKIRVSENCMKCGQSLCAGKYNYKKCTTCTRCFKSKQENCGFQRKLGKSSCRTTQSELNKILAYRFALGEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Y1</accession>
    <name>A0AAD5U7Y1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alanine racemase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005057</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000038">
        <property type="protein sequence ID" value="KAJ3226349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Y1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="4">
        <location>
            <begin position="8"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="198" mass="22084" checksum="B8F0B6D402D86946" modified="2024-05-29" version="1">MTTMLRSEELKINLEEIKKKIPNNVRLVAVSKTKPIEDILSIYNCGQRHFGENVQELVEKAEVLPKDINWHFIGTLQSNKAKALAAVPNLFLVETLGFLLIFSVVDISFTGSVKAANSLNKACEIRKEKLKVYIQVNTSGEESKSGINPNDAVQFAKHVITECHFLDLAGLMTIGFANPDLPNMKNPDFEVFFSFGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Y6</accession>
    <name>A0AAD5U7Y6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Small-subunit processome Utp21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001485</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000142">
        <property type="protein sequence ID" value="KAJ3223138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Y6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059157">
        <property type="entry name" value="WDR36-Utp21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007319">
        <property type="entry name" value="WDR36/Utp21_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840:SF12">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25171">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25168">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04192">
        <property type="entry name" value="Utp21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR36/Utp21 N-terminal" evidence="5">
        <location>
            <begin position="31"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="272"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="540"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="WDR36/Utp21 C-terminal" evidence="4">
        <location>
            <begin position="672"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="880" mass="99944" checksum="946409419384A554" modified="2024-05-29" version="1">MGIFTPFRALGYITIDVPFSISKRGTSHFLTTCIDHSFQIYDLDKMSLLFVGPKTELSITAIASHNDFTFAACGNSIIAFKRAKEEFTLRQNNYNDDKMDLDSRHSFSIYELKILGDLILAVCDDNVIRIWNHITREFHNQILFGSTFQVTTVIHPSTYLNKILVASQEGKMQLWNINSMRCIYEFEKSFSSPITYICQSPVLDIVAIGTLNGKIAIHNIKLDKELMSFSQEGKVTAISFRSDEHQHMCSANMNGDVAIWDLDSKTLFHVIKGAHDGLIMSAQFINGQPLLVTGGGDNAVKQWIFDAIDGIPRILKFRSGHHSPPTFIRHYGNEGHNILSSGSDHSLRVFSVIRDSQNVELSQACTKEKDWDNILTCHAHDSEARTWNFSRKSIGKHKFKASDNSNLKAVAVSVCGNFGFIGSSKGVIDMYNMQSGIYKKKFVGHNKSITALFTDNISRRLFSSSLDGNLYVTIYMIFFNSICYLQIWDVDSGKVVEKMDLNSPISLMQLHSESGLLAVSTDDFCVRIIDTETIRIVREFWGHRNRVLDMCFSDDSRWLISTSLDGTIRTWDLPSGNLIDCFKAERVCTSVSFSPNGDFLATSHVDHVGIYLWANKTQYSNISIKPVDDSEIFDYKLPSVGGVDDFDNDGSLSEKEEELSFEHLKLHNEEDMVEEMIRLSNIPKSKWQNLLNLEIIKKRNKPKEVPKAPALAPFFLPTIAGPTPKFFDNSVDTAEEKTNKSSKIVKINDMEVVTEFTRLLRDCGQNNDFSPFFAFLKTLTPSEFDFEMQQLSENNEFCDFILFIESLKAQLITFKDFELVEAYMAVFLKIHAETLIKDPLAVKCVQSLNDFLNEHLESWKKLESLMQNGICLVDFVRYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U833</accession>
    <name>A0AAD5U833_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RuvB-like helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RUVBL2_1</name>
        <name evidence="4" type="ORF">HK099_004416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U833"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TIP49 P-loop" evidence="3">
        <location>
            <begin position="19"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="91" mass="9539" checksum="4C9106D22315C5E6" modified="2024-05-29" version="1">MAATILTTPETKDLTRMERIGAHSHIRGLGLDDSLDPRTTSQGMVGQKNARRAAGVILQMIKDGKIAGRAILMAGAPGTGKTAIAMGMKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8G8</accession>
    <name>A0AAD5U8G8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8G8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="390" mass="45962" checksum="F0A31C81AF770E01" modified="2024-05-29" version="1">MPVQYALSYNKLRPTNDKCDKNLHIYATILKKETEKRRLQNLEKSTNEIKKRLLELNIKNSTRIVNNTHYNQTKRDTLKKESINCKNKIFGNVIEGTSTHQKVKKTSMGLDCKNFFSKKKLLTYKTNFNTITADNEKYNLDYLTKKNVFDDSESEEDVKIEAKSKKGYIYEKFLDKRVRVCKAVNVEIFEQGKFEQKMCFSENKLNNFLSNQKFDTDVNFDDAVYNRYLKKQQPLVTPVIEVTPDENTNFLNTSNNCDVKKPLLETLQQQEQEFKDVNYKENFDNICISGVSEDAEKESYKKDLNVTFNIEHSNEKNRIPLKYQQQELERNQYEQLLLENVTVDLSVPSTDTCFNSNNFKVKDSKTELSSNEPELKILELENYDFFEEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB89</accession>
    <name>A0AAD5UB89_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000017">
        <property type="protein sequence ID" value="KAJ3227409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB89"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033:SF1">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="6">
        <location>
            <begin position="168"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="97"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="698" mass="80984" checksum="65F19881CB95B2F2" modified="2024-05-29" version="1">MTDIKEKKFQKFQRLTYLISSSEEFTSFSNDSNNEKYLTYFKNCNYLQRENILNSLEQLEIEKNKTDQKLREFESPAHILKDANAILEHKKKEGVDMNVLQSKLKLIEKDNVAVKEEEVAVGRKLVAKKEEYQHLKDLETKIKNHRYDTKNLLKNILERLNICTKSEKIAVAVGGSKASFALCLLLKDLIGKDKFNAFVIDANIDERSSKIFTSTINSLAELDISYKILPINHTNQKAMNKIQCSDALKKKSFLSNFSTERNALLARMCEKEDITSLFFCQTLEDQLVSSIGRFFKGSGVYGLAGYKSVEKELNTAEFGSKFVKVVRPLLHIPQVKVDEIITFNNVNRCDLAPLKSPAISNIFFKVLETKLQNNELSDFFEKKSLVEDENPLSKKALSDFVLSMSLHKKYMTSNVKGIIEKNLKLTPEMGSCFLKIDASPNNYKTHWISNPFLGNKVLDYVVHWTDRFDKKRSPLSNVNEARLQIVREVNFDTHTITPTKKPRLVSLSRTIFHPPRSSNTGRFNWLVFTEPFKQKDIKDLNYKVKFNEINLWDKRFYLIIKNKMLETNNNKISSILYPHFNKFEFDQCDVFVKPFLQDDLQQIISVLKRLKKNEETSKIYSRLSHYARISPPQARGGLPCFYFHNTKTKAANEMQRIIIGIPSLKLNFFKDVFHLNLSYKKMSTFNRESLEKGYDSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTF2</accession>
    <name>A0AAD5XTF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007789</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000791">
        <property type="protein sequence ID" value="KAJ3212198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTF2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028433">
        <property type="entry name" value="Parvin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12114:SF4">
        <property type="entry name" value="GH23568P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12114">
        <property type="entry name" value="PARVIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3212198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="45759" checksum="7CADC745C29F2103" modified="2024-05-29" version="1">MSKKPTSRGVTSSFQTSQKATSLKYPVLHPSSASDHQLKTLKTNLIKWINNLIKPLHVKDITNDMADGQILACLIGIYERDHSSILKLLVNLSHVVGANLNLPSNVSIAVMKSITLDGVQKNKTTINEITADESLFRVEKTDLLDEFDVNDYYADDVFDELVNTPEKLEQVTVLLSEFVNDQLNPIKIQVNNLMEDLENGINLIILTGIVETINQLSLSNSLPIYYDILNKKSNNPNNEEFQPKFNSIFNKLSPENLNSNLTHQLASSLSNLENDKIFKSEIQALINFNNRLKGNLKSGDDENFGYHEEQDISGEDSYLLWDKKKSKKKNFLQKFFWYIKTDMTFRHGVQEKTEYFQDKLEELHSSEVNIDPIKRDLLYCLGGNGYELRYTQMQRKKKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTI3</accession>
    <name>A0AAD5XTI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="8">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PRPF19</name>
        <name evidence="12" type="ORF">HK099_007660</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000761">
        <property type="protein sequence ID" value="KAJ3212829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070534">
        <property type="term" value="P:protein K63-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="U-box" evidence="11">
        <location>
            <begin position="1385"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1171"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1243"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="343"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="481"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="983"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1171"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1199"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1252"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1264"/>
            <end position="1282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3212829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1883" mass="215980" checksum="5789AB7F8402E242" modified="2024-05-29" version="1">MSFSWAGIEERERIKKEAERKLKDFQLNQTEEIKKKLASRTLENIGYNLDGGLLGSTSNNLHHSSTSVLETQQRQPSNLTFNSNISQDDILMKLRYTEEQLIQERRSRSWLESELQSGKSVVSSLTAKVENLMECFRNENLILKDVQKQLEVQSRLNRELSQENCSKFERDQLKIHQMVAELAAKQRHFEQSNDDAETRNRTQLEEINNLRYRLEGFALRANEATTEVRATAHELDLEQQRAAENFRAIKDHDHALDVLHNSVESKSDALKRNMDLTAQDIRQRIDVESRNRVNFENNIKELYSDVRKVISNQERSLLDRIDSNRQITLQTVDKERQDRERSMAAVMENMRNWEKAVKETESQIIARVTEQLSNLEAKFNEDHNHRAKFEGSLRSDVEDGFRIIQQSLAKRGSELTENQNELKQRVVNAVKTLQESIILVEKTSEAKFNNYEQVLRAEIKSRMDIEIKMSQTVESLDEKLLEVQKAVIEQLDITSDELKAENKSIIEEISKTAEQLTQSKTRAVEDLESQIQQVSKRIKDDEFNTKETEKLINIKIESLQREYQEAIEASETKFETKLCGIKDEENDIRVKMSDTQIMFQDVKNSILDKFNIKSVQMDQTLEAFKEDLRLKLSIKDGDDLESRIKTQISSIFTSVGHLVQSNSNIKDELELRATKKELDEYDGKGKASISLINTKIVQINEDILKCNEDVATRATKKELLEVEDKQKLSTMELQVEDSKLLDLINELKEELSDRVFKKQLEEIEIRIKNQLSLLSDKENDLNVNIVNLRSELKTKASKEEVRSTETKITSNLDNVIESLNLTVDELKTNLEKQTKETYDQWGVAFGKLSSQVSTVELKADGLNTVTEGIKLKISDNEKILRSQIKEAMQSQESVLNAELLLLEKIKEETQNQIKEVNIKIEDIPRTLHYNDMQYAEFKRYIAELLQKEQEKTTYLLTELRESLQHKVSEQDFDKVQGELHGNIQKINSKIEIEELSIDQIRNRIQEIESQARERLREIRSFQERESGDMELKSRQERDLNVKKFEEIELKLKNIPKQIEISNNELRNLKFKFEENFLQVEFLNLKKDFINFKNELGSKITKKNFDDNIELFQSEMRRKFDTLNTRLNEIKNSQDIAKFNNIATSEKDLKELSPFYSTDDYKKKMEEKNTTNYSSSLVTSTSPQPQLIPGSFFKPTHLNLKKEEEPNVQKKEEMLLKKNSNTINESYEIKPESKSKEYFADNNAMYNIPKPPSNSQLNNSSITNSASPRPKSKPTTPKSLSTSDVAINSILNENNKNTFSMNPLNKSLDETKISSVNLSSSSKNLNKSLELNKSLTNLSKSSNELNKSVNNTSAKTGSKNKSNLSLELIEKLADLATNSDLKSTVIQLPVNSPKVSGEAATDPVITPSGNLYQRDLIEKYLLEFNKDPVTDAPLQKEDLIKVNLTSTPVKPKPPTATSIPSLLINFQQEWDALMLELFSVRKENLDLKRELSLSLYELDASKRVIARLLSEKSNEARVPEDTYQVNDQMDVDEENSNDKSSNTFENKLTSANKELAAARKKRKAPETLLKAPDVVALKKGKEISTTHNHGITTMDFLKIKSTTHNEEKASLFLTGSKDGKVTVRNALGEQLFTQKIHKKDVTKVLFNKFTQNSFFTAGKDGVVKQFEIHEDAKKGWNFTLKAEFGNLEENVGGVSSIALHPTGEYLGSSNFEGGWKLLELENFTVLHSEEGKGYLCLSFHPDALILGLGKSDGDIEIFDLIQKTVVQTFSQKNEAVKTLFFSENGYYLSSTGTKSLKFWDLRKLKLVKEIDAEEGEEFGEGKFDDFGSYFGIAVGNKIKVYLNKSFNELCAFDLEHHVSDFKFGEDCKYLFASSSDQGKILFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTP0</accession>
    <name>A0AAD5XTP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Chitin synthase</fullName>
            <ecNumber evidence="2 10">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CHS1_3</name>
        <name evidence="13" type="ORF">HK099_007524</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cell membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 10"/>
    <dbReference type="EMBL" id="JADGJW010000736">
        <property type="protein sequence ID" value="KAJ3213190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTP0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="602"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="635"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="681"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="716"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="823"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="862"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="12">
        <location>
            <begin position="175"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3213190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="883" mass="100773" checksum="E7167F490F32B010" modified="2024-05-29" version="1">MDNQYIPGAFPINSNLNNTFQNPVSSRHINHNSEPHEVINMQQRNLMPSPGRQEISTTNNLNSYQSMPSNSNDTIQIDGRTSDYTFLDSTQNDQSENDTTQIFASKPYYNPGYPPHLQALQGQQQWQSPLRQQLPPQNQQYQQYGRHMEPRVHAVNFGNYYNNQNMLPAPLFQFKTKKTIKLTKDGNFVVAIPIASRVLPEKNSKQGREFSTLKYAAVVGDPDEFVGRKYSLRAKEIGRVTELFIVITMYNEDEELFSRTWNSDGREKIQKKTLSYLGILGCYQDGVIKTSVTGQPVSAHVFEYTTQIGLDKDHNIKKEAQIPVQVIFCLKEKNAKKINSHRWFFNAFGAVLNPNVCILIDVGTKPTEPSLFNLWSTFNKNPYCGGACGEIFTETGHCGVKLLNPLVAAQNFEYKMSNILDKPLESCFGFISVLPGAFSAYRYAALQDGPLEKYFAGEKMNGDVNIATANMYLAEDRILCFELVTKKNQKWILRYVKGASAETDVPDSIDEFISQRRRWLNGSFFAGVYSLSCFYQIFRSNHSFGRKAALLIQSFYNFINLLFNWFAVANIYLIFYFLTANLTIGATAYLGPNSIFSFGPTVGIVLTILFNQVYFVAMFLIFLASLGNRPQGSKVIYGICFFLFSFIMTIMLFLSAWTIYLEVPKSQTEWNNIYGKLSEPYFFGLLISIFSTYGVYLLSSLIYGEPYHMFTSFVQYLLFLPSFTNILMVYAFCNLHGAFFFDVSWGTKGSTTENIDLAPVEVVQTDRGVIQATTDLPVNQNDIDNKFSDFLEQLKTKVDIKKKSIDPKTLQEDYFRLFRTRVVLFYVFTNTLLILVMITPYISNNFGITSVTDDRNLYMTFILWSIAALSIVRFIGSVTYLMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUF8</accession>
    <name>A0AAD5XUF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002015">
        <property type="protein sequence ID" value="KAJ3199891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUF8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041971769" evidence="2">
        <location>
            <begin position="24"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="171" mass="18609" checksum="8E54FACFAD69F94F" modified="2024-05-29" version="1" fragment="single">MARASPTVTLLLLGLSVISLVLAITQPLVSVAGYYDLHLFPDNDRFDYKVSNTHRASQAMHVLALVSLGTALLVLIVSHFTSWPDSTFRKMSAIQRTATVFGTAFYLAGVATLLKIAMDYKHIADDLPVAPNGSIEAGGILDIIGFASAFVSCMFVFFSTSRDNTDEYQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUR8</accession>
    <name>A0AAD5XUR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002079</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001667">
        <property type="protein sequence ID" value="KAJ3201821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUR8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF25">
        <property type="entry name" value="MICROBODY (PEROXISOME) PROLIFERATION PROTEIN PEROXIN 11C (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3201821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="141" mass="16354" checksum="009D0B437E0675FE" modified="2024-05-29" version="1" fragment="single">LNRLQNGANLLYYPLEHIYWLAAHEVIPLSEEMKNKIGMWSTRFWASYVVLYFAQLYIDNEELKTRECMLKSRALEKGKSDAGSTDITFTKDRLNLIEERRSLFLNFLVNLSYFPLTIQWSLENSTFPYIGVGICGTIAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV90</accession>
    <name>A0AAD5XV90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002165">
        <property type="protein sequence ID" value="KAJ3199205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV90"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="2">
        <location>
            <begin position="137"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="291" mass="34356" checksum="DAB8C2F453204A34" modified="2024-05-29" version="1" fragment="single">RKKIEAEYNLDLEKEERKILDEHIFEIYSSLEDEEDEEELDDDEIAEIKKKKKADGEDRELPKKEKKSKSQVKKEDDRSIDEDEEYAKKLQKEEELMSRKRSSRNGSTGGTTSVKKRKLKKAKKSNNDDNQEPRKNGFNKPLILSEPLSEFLGGISEESRPQVVKKIWAYINLQDPKDKRYICLDEKLGNVFKGYGTKIHMMSMNKYLVDHFIKPEEVLDYKSKKSKKVKDEEEEVKDEEEEVKEEEKEVNGEEREVKGEENNSNDDDNLFDEEGNFIKEENTIKKEEIYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVI7</accession>
    <name>A0AAD5XVI7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitrogen permease regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NPR2</name>
        <name evidence="2" type="ORF">HK099_004614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NPR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000330">
        <property type="protein sequence ID" value="KAJ3219719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVI7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009348">
        <property type="entry name" value="NPR2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991:SF10">
        <property type="entry name" value="GATOR COMPLEX PROTEIN NPRL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12991">
        <property type="entry name" value="NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06218">
        <property type="entry name" value="NPR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="333" mass="38453" checksum="929A0CB7F54021EF" modified="2024-05-29" version="1">MARTFRALEVESEFLSKSETKKELQNILEQLVEDLNYYSECQIPINDANTINLKLFPIYPDPPPVRDFQVPVCIIDLEMVMDKYCDLTMRRVVPRINGVNTIKKISELADVRVDLARSCVQHLLYYGCVKLVDIFQFSNVYAPKSHLNSMLNNIEAQNNCIDFVTLNGYPPVSFDRIFSLYCALKHELSVKDWIEDNEVWNHHIDVRINAIRRFFIYGVLKGYIFRIHKYPLIMQSSAVVEEELGYINGTIKEQKSYGGGMAGLVSSSVGKSVSSINYIPNNNFSISNIKRFLDGKHCFDELCTMFDCSSKELEELLKEKDKEKEICLRFLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW24</accession>
    <name>A0AAD5XW24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Small nuclear ribonucleoprotein Sm D2</fullName>
            <shortName evidence="10">Sm-D2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">snRNP core protein D2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SNRPD2</name>
        <name evidence="12" type="ORF">HK099_008018</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000839">
        <property type="protein sequence ID" value="KAJ3211360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW24"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030532">
        <property type="term" value="C:small nuclear ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01720">
        <property type="entry name" value="Sm_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000069">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027248">
        <property type="entry name" value="Sm_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12777">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="33"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3211360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="109" mass="12500" checksum="FB42C6EC51C79549" modified="2024-05-29" version="1" fragment="single">MLNPAKISDKPKSEMTMEELAQLEEHEFNTGPLSLLTQAVKNSSQVLINCRNNRKLLARVKAFDRHCNLLLENVKEMWTETPKSGKGKKRAKPVNKDRFISKMFLRGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWK1</accession>
    <name>A0AAD5XWK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001080">
        <property type="protein sequence ID" value="KAJ3207096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWK1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="516" mass="58888" checksum="0DB3B931E8DD0781" modified="2024-05-29" version="1" fragment="single">MALFYAFNNHRQILTPVVFNTIIKRGAALPRFLIQLVDKEYHRYERGLLERSATTLVSSGILISFLNRGYEIYKEDIEITSDDNASFERLLYSIPSPVEEIKTLILNYGFTPTRKLCSTPLQDLIYKLSKLDISLIDHLVKNGLDLIPINDAVMEKVFRDVTDQEVFVSYIKHGFKLTDQTIKKGLLIPQPAPLTFLRACIDSKHLEELAHECMVDLLGPATRIFRAESADHLLLSFNFPTSVMDKAVLVQSGVSFPNTRSYLKTYPYSVWRWILRTYGVNHRYTGKVFDDAISRAGIRFVGDPELHSLHDVFLDAGVKFKPHHVKILACRLLHRDMSANALHLINVLKVQVLSTARQDTFIPVDTIKLWIRSFKTEVIDNDDWNNRMRTIQLEGGTLGGVYRINRPPEDGLKFLNESRDIVDELSKCLVNFDRVLNSDEGLLKRRMSTGSMLQAPPQAAPIINTVEVVLDENVKHKRKFSLIKSNVENTIKNHHDSNENKISSIQSGEISIKESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWQ3</accession>
    <name>A0AAD5XWQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000108</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001008">
        <property type="protein sequence ID" value="KAJ3208180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWQ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052032">
        <property type="entry name" value="ATP-dep_AA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585:SF2">
        <property type="entry name" value="ATP-GRASP ENZYME FSQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43585">
        <property type="entry name" value="FUMIPYRROLE BIOSYNTHESIS PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="131"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3208180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="520" mass="59466" checksum="35D389BADC4C9971" modified="2024-05-29" version="1">MQLRTESEYSHVLILDDMGTPSVDSKISTFSKFLNENDKVKLMIISSVGCITEEDKQKSLAWLELDPYPTRNGLLEVHVLEMHSKYRIDKIYTHQEELVLRAAHLRELLGIEKDGLYSGDALCFRDKYVMKKIAHEGGFPCPKFKKIMTPSDIVAFTNCNGYPAIIKPSMGCASAGVHVLHCKEERDFYLKNEFYKALDELNGQLDHSGDLIIEKFVKGTMYHVNGFAKDGVIQYCWPFKYFNNNLDFTMGKTYGNLLISRSNYKWNILFDNAQKLLNVLPKSKNLFFHLELFDEDQEVGAYSCGEEKQMNLLMCEIAARKPGGSIGNLIDNFQIENNENWTSFTEFVFRVSIGLEPNQKITSLCDPQAKFDSFSVTPSIADLMIPLQKGRLTNIPFQETCPVKNVQYIPISKVGTCYQGYNINKVNTSSRFVCRLKSDLKNNFNDETESEMVLRLACKWFELEVKYSLSTANIEFDAETANGDVIDMKKFDVDNKIANVFNEKFGLNHQILKLEANQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWV0</accession>
    <name>A0AAD5XWV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002134</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000169">
        <property type="protein sequence ID" value="KAJ3222580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWV0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="206"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="319" mass="36827" checksum="C31D47040A98DE71" modified="2024-05-29" version="1">MARDRTKELHDFCNIQLKEIITVPSDSTLTDSQEVSSCSSFHILKEAELIESDFENIIEDLKILENLHSNILNEINRDKIPDIQTRIDIQVSNLISQLERSKNHIKNFSSASGNKFLFSEAELEIRSLQAKRLEKEIFKLVKNFYDLQKIFKIDKKKQIERQFKIIRPDATPEEVERILDPNIGDVKGFFKQEMLQSSLKGKKEQLRVCQERHSELQKIEKTISELLLVFNDLGSMLKEQDTKIEAIERTVEVATETLEVANVEIVKATKYVKSYRKKARIFCVITFFLVLIAGLATYFLLVKPALVNPISEVVRGLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWV5</accession>
    <name>A0AAD5XWV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000168">
        <property type="protein sequence ID" value="KAJ3222602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWV5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="16579" checksum="460B0919025B4A94" modified="2024-05-29" version="1">MYKLHIGTSTLLQNMKQVHQPTVALISSINTFLIKLSTIIPRIKRNSVVNDNRSSTRTALNASSNLSSNKALSEDANDILQKGCNRNDDRKKQTLSTQIETSKVILKISNDKLKQISIENFKRSGCVANLKKQVLIQNLIKNVDESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWW8</accession>
    <name>A0AAD5XWW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RPT1</name>
        <name evidence="13" type="ORF">HK099_002004</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000163">
        <property type="protein sequence ID" value="KAJ3222694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWW8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000005">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000037">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 13" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="208"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3222694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="433" mass="48390" checksum="88B0F034C88ADA2B" modified="2024-05-29" version="1">MPPKKDWEKYEAKLDQDETVIKVLDEGDIALLKTYGQGPYGKELKKIESDLKDMQKRVNEKMGVKESDTGLAPPNLWDIPADKQRMQEEQALQVARCTKIIDASEGDVAKYVINIKQIAKFVVGLGERVAPTDIEEGMRVGVDRHKYQIQIPLPPKIDASVTMMQVEEKPDVTYGDVGGCKEQIEKLREVVELPLLNPEKFVNLGIDPPKGVLLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAIGGARHDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFNLPDLEGRTGIMRIHARSMSVERDIRYELIARLCPNATGAELRSVCTEAGMFAIRSRRKVATEKDFLEAVNKVVKGYAKFSATPRYLLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXD8</accession>
    <name>A0AAD5XXD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000463">
        <property type="protein sequence ID" value="KAJ3216719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXD8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="315" mass="35682" checksum="DA3741AB140F2365" modified="2024-05-29" version="1">MTGALAQEIDLSTFSSCLLVVVTYITVENLIVFFKLFKRVTGLSVLALTMLMSAHVNCVSVWVAINKPPSNDPTSTVGIIYNMWVGIIWIIMVVTSFWFFKNRFAMLNVKGKLQAKILNLLFLVMILVVLYTIPVFMLYTLGLRSESDSKWDEISEVMLCYLCETVLGVTFLIELHKQSGNNLAKKTALHIKKSVYLMLVLDLFAPVVLFTMGPFFCYQTKTFSYGIKARLEMQMYDQIKTLVENRETLVSASDHSSVESYDNNRKVNKKDAGFTCKNCGSIQNDRGVIIEKSAYSEKVKTIERTGEGKKKKKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXW3</accession>
    <name>A0AAD5XXW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000084">
        <property type="protein sequence ID" value="KAJ3224701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="356" mass="41359" checksum="7C15E97ED140A442" modified="2024-05-29" version="1">MLIPLPESSNHKHLSLINSILNAFYKAEVVTVIPYLFPVINEVGDVAKAYVTGYQMDPTFKIKTNILSDIGQRQMQNLENLVGFCKGLKNREEEVEGGSNFYNFINESTVKNFFGKNYQLPSIHRNLEKIFSIDSCFKVEHWILTSCKAQKIGNRERVTDFEENFFFSFEQLFELDADMKNDCNEKEKSVEENIDLMKFDRDVESEDELSYLEEKKIGHELEGVFESFHSAENFEDNLSTSSPTTPTLNSFYLKNRVKSENEITEELMNKNAELIVESEKLLTKVCKEEKEGLQDELELMFESEEEVMKKESEKEVMRKENEEINLIKSAEVENSNEKSGKSVDYFDELSSRFKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYA0</accession>
    <name>A0AAD5XYA0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYA0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086:SF10">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="3"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="60"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="163" mass="18523" checksum="FA339C2C0871684A" modified="2024-05-29" version="1">MEKDAHIVFYCRSGARARQALFLAKNKGFYNIQNFTGGWLSWADRSVCSKQDVEAVVNNAAPNCHLIDVRDHTEVAHGVIPTAKHLPIKEMIEAFRLPASEFKERYGFEKFDPAENLIFYCKRGWRSEAACYIAKKFGYKNGRNYKGSWNEWTSTDSSSGAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYA1</accession>
    <name>A0AAD5XYA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_006373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000543">
        <property type="protein sequence ID" value="KAJ3215441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYA1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="88"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="201"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="337" mass="37609" checksum="E4AD430EE922C00E" modified="2024-05-29" version="1">MKEGATSIQSSIFDAMLCGGFSGGQLTTSTIRYYSLPHAFQTIVKEEGPRALFGGFTAACYGAFISHSAYFLSYEFLKRKLQHEYKVNETSSYLISGAVGDIIASLIYVPTEVLKTRLQLQGTFKNPSKYSQHHYKSTLDALKQVYSHNGFLSFYEGLGATFLRDIPMISFQFTFYETIQNAFLRNKIFTNYNNVTKLHELTVAHDMFAGAVAGTLAGAITTPLDVVKTYLQTQKQPPKLADTLTSVIPPSVSSEKISNSVPKPRAPAFYNGIISALVGIYKTEGLKGLYYGVGARSIYLGTQSMIMFVLYENLLRHLRVYRMESGMRNFDELNSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYE7</accession>
    <name>A0AAD5XYE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycosyl transferase family 25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYE7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06532">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002654">
        <property type="entry name" value="Glyco_trans_25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01755">
        <property type="entry name" value="Glyco_transf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl transferase family 25" evidence="1">
        <location>
            <begin position="54"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="307" mass="35818" checksum="3AF6AB028025A0DF" modified="2024-05-29" version="1">MFKENATLMKSCIVDNINVTKLEESYIRNGNHEFHDARKMIVSNAKPNYFGLDHIYILNVDHRIDRIATMQRIFEKLNANFTRISAFYKKNYEFLNLYNRVVAKGWKQTAAAYAIKMSHLKVLEDMESKGYETALILEDDVDLDLMIGSILPLLLKKLPVDWGYQYHFKLRFKCPQFLRIYYLSYLKSVTPYPKHNSLIYPMGNAVAGTQALIYRNFRDITHNKTVIQKIREFSEVDIDNPWDYMLAEMFIRDDSYSIKGYGSDFALAEHMGSTIANPSDNKDVPDATWKDEYTANELLSSTFFSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYL8</accession>
    <name>A0AAD5XYL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003808</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000255">
        <property type="protein sequence ID" value="KAJ3221052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12091">
        <property type="entry name" value="FANCM_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20075">
        <property type="entry name" value="XPF_nuclease_XPF_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1320.20">
        <property type="entry name" value="hef helicase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like_ID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025">
        <property type="entry name" value="FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="FANCONI ANEMIA GROUP M PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="193"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1735" mass="197794" checksum="C799C53D111EA7B7" modified="2024-05-29" version="1" fragment="single">MDEFEDDPFDNFDDDLLLAAVKEAENQYQMQQAQNLNKVLLQQEPNVNKNSFYHQQSLKVQQTPNFTQFKMHGVEKSFNQGKNNTINTFNQQKINKQSTIFQSFGYTNPPPQKVAIKSNKAIKEKQIVFPSKYHQINEKTQHEWIYPTNLPIRDYQLNIVKRCLFENTLVALPTGLGKTMIAAVAPTKPLVAQQIEACFKITGIPPNLTLEMTGSCPSDAISLLVIDEAHRATGNYAYCEVIRELSARNESFRVLALTATPGADAKTVQEIVTNLRISQIEIRTEESKDITPYTFEKKVEKIIIPPSENIIRITTDFSKIVQFYLNRLMKAKAFYMNDPTLVSSYALIMARTKFREKSSALTQAQSSFIEGDFGVAITLCQTFALLSQHGIRVFHSRLSHYIDESKQAGNKISNARRQLLNNPEFNRIMSYMNELIADINFISHPKIERLVGIVVQHFIENEEIKETEKRETRVMIFSQYRESVEEIKEVLSKHEPLIKIMSFVGQSSGKRSGKGFSQKEQLEVIAKFQSGNYNVLVSTSIGEEGLENNLDKSHNQYKLVQKIILEGKKLNMFPVNSMLPRGCKPICNKRLIEIPKNSVEIFGKKEVMRDTSSSSKVNTTNSSPFLTAEEFEIYSVKHPKTNFNIPLSLEKYTHWNTTVLTDGIISRSTASVALVKNLSLMEDLQEEKHKGKENTLDLPAWLYTKDVVEGDSYFIKSIKQFSIFNKKKNLQTPLDSKITSSTEEANQIVNSPLKDSKNILKTRKFCFSSDEEAASKSASEKIVKKPKLTKSTFDLGDQTIFFSSSEDEEIAKVKNLHVTNKSNEIKPSPFMTETVSDSNRSDPVQIGAGNDGSCINNNSIEKVDKIESKKSDSKNFANLCNSQISEFSDAFEINSPQLVGPEDFVTPKKKFMVEEKRIGDISNIEADFNLRNNRSTVEILEPTLDLKTNIPATRLFDKSNTCLEHVPEDLYFGTTPSELMKQLGICIPQEPEANNLSATIAEPVNNAIEVNQKIYEHSRIHEKFSEDYDTVIAELHEFSPRASKFDTSSAILNDELLQESTMKTDSVAIPFVYNLNNATPLKIPLKPINETPDSQPIVKNRRKKITFSNSPVLRNEINSISQLPLNEIVSEKKQYKRLQKINLTEVKRDLNCDDTNANFDVNNDLKIKKNLNPSLILEKINKKKKLPRRSPLIRRTPNLNQVKKVRTGNKKRLERKIKHDNPFLEYEAEESLSDGEGGVINSSVISEDEYFSDNPALDQDLEGFVISEEYYERTEQTQTAVYLQSLRSPEVDIVAVQSHAQKLRYVGGGVEDESEGSMKDFVVDDDIVDSPLESKKKFKCVNYENGKKFNEPVNYFVKDLIDDDDFEYTKKSDKYRDNNFLDIVSPKNYKNVSTGAKVVNKFEDPTKEQNFLEESATSIPQSPFLDINENCTKKHQQQQHHQNENQNKFQFNQFNNESFNKTITTFKPWQKSESQPNQLIKNKFLQAEEKTKDIFKPWQKKLENNNNILDNLKPWQKKHEPIDQAVKSTFFNAGNKTVNTESSIDSTFSQKYSKRKIQILVDTREMKTLICSHLRNKYGANIIIRQLVVGDFIISNRIGVERKTKSDLLGSFIGKRIFEQLNNLMAYFEFPVLIIEKDRKIESIPNHKEAQYEGILASLQNTKVKIISSDSCEHTAEILIELAKLEDQEEIQIPLTLPDKSNSFLQLLLSVPSLGDVTAMLIVNSGITTLGQLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYN8</accession>
    <name>A0AAD5XYN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003962</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYN8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="42948" checksum="DB04839C0DC99B70" modified="2024-05-29" version="1">MPCRNPMHFPTSISRNEYLELFFRAYSLISSRAFHIDEYYDDALVPLADLFNHNSFEDIFLDNNKDVCYNCGELHCFCETNQVQTKKTILSEKEKLQNLSARYLEVVTVQSIKPNSEIFNSFGKLPNSVLLTRYGFVEENNPFDVVHFSEKEFINFAKREKILGRFNENLLESRINLWKSCRSRIDLIEEGIDIQIENMASEILQTSMGEDFQMDIEDCEDTENPDLLDDPVSYNITNDEDAFEVVKSTDLTVDSEGVPDVGLLTLAVLLQKNVTSISLPGSYASVLKVPLHSKYSSIIPRVITAINPPHLSNYTNSASLHLHSSLNLNKKSSLLADLETEFNLEFNESSFFKQVKTVKDVCDFVINAEVKNSLGIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYU6</accession>
    <name>A0AAD5XYU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000227">
        <property type="protein sequence ID" value="KAJ3221488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYU6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="600" mass="68145" checksum="06CEEC1280A941A2" modified="2024-05-29" version="1">MEQKELNVPKEKKTELNEQKINSVDIDGTLKSLGLQVKDGEKKKLESLLETAKEMYAVMVFKKINSVFDQDEDDYANEEHKFNEAMDTYSEYLTTLHSAKRKNSLARDKPIPVLNVATSTPLTVNSVIEDSIIEIPENLDSNEDLSKKSVQNDFIENTKSLSKLSSASTISSIEKDKFSRKNTGSLSSVKVKINSVQNVAAEQPKLKKVNKKFANQKKKKTIINPPKLVSSTDDHGTDFVKKKVNNNTNLSQNIKRNLKPRLNQIKSNIPFKRKPFEIANKEISEAASEKNVGVDASNIPEKKEVEVEIKPPRTPLLDVKVPAILYQNTAAFNIQSSLPSDYLSLKGHIQLNIGVSAPLDAESLYSKKDKFSLDEKRILKDKFHSKKTIGDEDMYLNVKELNNAKSAYRRQHFNRDYFHGDINKGDEVNFEEYDTLNFTKTWMNTENTGKNYFVEQKVEIPKESKTDEDLGIVSGKVPEDVITIKNEVAVKNSTNSTLATTSAVKILEKNKPEKRFTDSFRDKKIDIVNNKKKLRLSSKFLVSPTSFELLARSKLGDRDNIGFSRDLKTHFCAFDFGSKTLLPKKRNDFLLPIVQLKKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYZ5</accession>
    <name>A0AAD5XYZ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005392</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000417">
        <property type="protein sequence ID" value="KAJ3217633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYZ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23165">
        <property type="entry name" value="Prefoldin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016661">
        <property type="entry name" value="PFDN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100:SF9">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="39"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="440"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3217633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="504" mass="58066" checksum="9F5FC31DF2DA338D" modified="2024-05-29" version="1">MNLEVAKEESDQELLWEDQQNINKFSKLSNKILEKNAELKVTLQEKEYLEDILQELELADEEEEIKYKVGGCFVSLSLEQVQQRLQDSLKEGEKKFELLTKEIKGIDDEMSKLKVLLYGKFGKLRRFHQFGIMGKTKDQLICPTWFTRRHDLERHFRTHTGDKPFKCPRQNLNCFASFSRKDLVLRHMRSIHKEDLVNSNAMLNNNKDDFVLFSENNDDCLNISLLNENSLIDENFFNLSSNILNTSVSNDNSFDGQIDNIFTNFSTNSNLNENLNFNFIQNDSFVNHGNSYSKFLHNAPGKAQANSAVDNSIIPEQDYKNLLSQLQQNHFSIPLDNNKHTKIPESNEKLRSSKAVDVVQVEKVSEIETVKKAITEEDNAGNGAKKENLNLVNFTLENLNNVKNLESVITNPLPPHLWKERFSEILKNEKISKNLSNLWRERYSNILNNADNVENNLENKKHLITNLKKNLGKLDNSLNNGLLIDLVLGNEETLPSGKSTRCFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y093</accession>
    <name>A0AAD5Y093_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000229">
        <property type="protein sequence ID" value="KAJ3221459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y093"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="581" mass="67635" checksum="A4250B1EE9C17015" modified="2024-05-29" version="1">MSASVNDLDALFTPDSTLTVSQSLNIPNIILRDLQIQVVNLKENLELATKTLNFLTNLISKDFPVFSESASKEGDYRTLNLIYKFLVSVNTEEQKQILSPVQITTNYKNLFNVYIKSLEFLILAKVLNIEKKFVTLGKFFSGHLTRFIKMNRILLLENLPMQENIDLIYSLMRVFSVGFKSTWEEADFLIHHLMNLIFAFLSTKNSKTSIHSSEEAYFKGLLLRRLETDITDEKAIVEFKNSKLFLLTTIITTDPDIKEQALFIEFGFSELFLHCLEKKYDFKSLLNDQNYFSRCVSGVLFFTSFLPQALWEKMELQLFKIFLELQESTSCNFLIECLSEISKYAPKTYLTNLLENILPNLLEENLKNYLTLKKISILYLKLLKNVEFSNDAEINRGKEIAPSKPKFIQKNEFFNFIVENHLEVEFKLKIWLNFFVCFNPNEIFLETITIWKNLTLLLSENQNNEESMLEAFSTLYLPLKVLALCFNFKTNGGTTELDDLEEILCMILILIQNSREVIEKAFHKCDIILMEKIKNTVEELLRFSGTFEKYLDISHSESITNYLLEWMESSIPLKNFPIIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0K8</accession>
    <name>A0AAD5Y0K8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000073">
        <property type="protein sequence ID" value="KAJ3225023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0K8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="320" mass="37536" checksum="836A3AF8C3A6FEC6" modified="2024-05-29" version="1">MKYLTVEKITYLILIDYYCDNAKSDQTLVISIEQQKSLTNLLLFLHDQVNCTKNLKHFKSLNDILVELNDISNKYTLTEVSLYLLFQLKKCTSSSEEFINLFKRIIDLIENPESSSPNDASVFPTLLIERNSPFGLFLRRCVLDFNNLLLENLVDFQNRFMIPYFKNLNLKLFQNLSREELNNLNSIKFLNNDGEEIEENIIEDVFPKLVVKSEVNPTDEFLVYDDCFKYVEKLVEMLEILFNENFLIFNFSQWIIVTFDQPLEGNYETLISAVVTPTFENDLFFLQDKGLNICFKKFGNDYFTLEWVTITANALFKALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y110</accession>
    <name>A0AAD5Y110_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y110"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031537">
        <property type="entry name" value="DUF5092"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382:SF69">
        <property type="entry name" value="FI18408P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17010">
        <property type="entry name" value="DUF5092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="669" mass="76163" checksum="2D979309D07FAD0E" modified="2024-05-29" version="1">MSIIEVLGKDGNNIDTLDSSYIDPFTLETIETQIQEHSAVNKNLILARVQTLSTLNNKQYFYYSAGQLNKVIFRKLSNPGGAHFLFRLQTLNPLTNTEILGEIEYFVFQNKKNSKANAFLKTKATSNKKLNSSLNTVSDSIIKEELLKNSVGSELRVAEIYCENKTQKILKNEEKNSDSKLKNFRSKSLGILRSITEDSYQNITDEENNLLEKKHFQSTENIKDKSLLNRSSFNRAKSLSIYKLTLRAKSLESQSSKITLRGNLSETILKDSKTNPLPTPLTNLLTENLSKMGLNSGNIEKCGYFSFLGTENDYIQSGTFRKYFKKNALNLEDAKLFELPSESLKSEGINMPAEFTWNEDTNMPQLLNEIFENRINQENYSLIEILINPRLHYRLLDDSSTTKTLCDVVLGKALWKSVVLPSKFKSMQSLNILMPYRTKFLVSFKKSDGIPLPPPMPGSIKHWSYLNTFFEIVLPNIKETILHLNVTELGANFTEANLRDFSSCSSLQSIDLSGSCLLKEDALLEFFISINLNEQSNLSRIFLTGVTFTTDSLLNSICNFKCLKMLSLSGCFQITDIGVAKILKSCLMLTFLDISFCFRLTDFSFHELGNNQVGYFLDSIYIHFCYLLTEESLNKIVRLPNLKKLNVQKITVRESFQFPNQILILTDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y209</accession>
    <name>A0AAD5Y209_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y209"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="8"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="329"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="773"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="857"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="687"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="977"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="687"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="708"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="996" mass="112418" checksum="1B98F8DD61F27C67" modified="2024-05-29" version="1">MECTLIIPEAHLKSILCVQYNHQYRYIYTGGEDANIKIWEAESGKLLQTLSEHTGWITSLLFCKELKILFSVSIDGCLIAWAQTGKLLQRIQTGSPIYSLAFNSRRNQILAGFNKKVRVFQFANSEEQNLNSNTNSQNNQKILETRSVACSEHTDVVSCMVSCEGRYYSGGYDKKIVIYDIPHHGDLKLQVSKVIRDAHDAAITCMIFGKDADNSCFDRVVKLWSLDGTLLQRFDGFSDTIVSLSYVLPTQTLWISANSSSPIIYDPRSGINVTDFTCVDEEKFNSQSSTSFWFKQMIYVAETSQVMGLTNKRSLVIWKYNPNAAVTILSGHTDSVECLTFTSKEPVLIFSGADDGVIRKWERLQLNTFMYSQEPLILPKEEQKLSAEDLKLLESKKYNIGNDLPEDRRRIQALRHRKVSEKLDTWKRATMTIDSLVHGKQVELISRHAQSTFRKATSKNIERGVGNSNIDSGLNNKSKFSGKIEKRKSFSESEIDVNCSANNILNNNNENCTYDKFNSCDSKSKNYQSLRKPSVLSLFYYDELDILCCGSEDSRIYVFGYNEEAVRSTASGNANNQQQQTEPKFSSTEENICEKGETNSENIYNHGEGRITGLKNDSVTNRVAGMTIKFCLKEHKDAVTGLFCFFKDGMHWLLSTGWDRRICLWDIKTGQLRDKFRNNSLPATLSNNMHNLTSKLNTPTATSTQKKSNVSSNSYSSNNSNNNTLEELAADDIVLGLDYSMERNEFCYCSADKLAYVRKFSPIASEMTLQVVLQGHEAEVTVVKWNKKNSTWITGSEDRTIRIWPAEGIPCLRVINNDSAITALCIDVLNGCLISGGQDHVIRVYDPAKNDEVVQKNFGHFDEVRSICHLSIRNQYVSGSWDNTVRVWNAYIKTGQRKGIIESTTPLRIGEDDPGFNLNALITPRLNQNFQIAAASEPATVNNANDAFSQNMEQIRLEDELKNTIIEIENVLKPERGRTPKVSTLPPIPSNPIHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2K3</accession>
    <name>A0AAD5Y2K3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription factor iws1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">IWS1</name>
        <name evidence="6" type="ORF">HK099_008035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IWS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000084">
        <property type="protein sequence ID" value="KAJ3224717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2K3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051037">
        <property type="entry name" value="RNAPII_TF_IWS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010:SF1">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="5">
        <location>
            <begin position="212"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="304"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00037992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="44539" checksum="5758602C51AE315A" modified="2024-05-29" version="1">MRSEDEDDEYDKKSQRQEHARGDDQQAQLKDLFGDTDDEDDLDDVDPNLFNDIDEEPKKKLQKTNDFSSESDEDQTYNRKLPKFKKKLGQSSGEGRKSKPKKQKPKEDEEERQRELTPESARREEVKKDIEAALNRIKSNQKVKKSELLDEAEMDEVMVRMVQKMKDAAENDQELNKKRQPAIAKLKLLPRINEQLTKTALAEQFLDNHLLEGMKAWLEPLPDASLPSLDIQRVMLSVLQTLPIRTDHLRESQLGRIVMFYTKCERILPEMRKMAQDLVDKWMRPIMNRSDNYRDRIVYEKDYDPRRRNETSGGGSGEIRDRRMPRPENLEKVQIPQRNVNFDYVPKSNLPNTYEPAKSDQAWKKLNNRLLNLKRKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2Q0</accession>
    <name>A0AAD5Y2Q0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000047">
        <property type="protein sequence ID" value="KAJ3225989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2Q0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="8014" checksum="D270B3CE8B5DC7B6" modified="2024-05-29" version="1" fragment="single">RMRPVVWRRKKHNNYYWGLMKHQVPTKGKGFREMFKKVGFDVFLCNEFLTSSICPVCKKRSLETFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y360</accession>
    <name>A0AAD5Y360_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MRH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003761</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000025">
        <property type="protein sequence ID" value="KAJ3226969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y360"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031606">
        <property type="entry name" value="Kch1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424:SF1">
        <property type="entry name" value="LOW AFFINITY K(+) TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16944">
        <property type="entry name" value="KCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="542"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="5">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="632"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="717"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="717"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="738"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="752" mass="86943" checksum="042AE0EC80727516" modified="2024-05-29" version="1">MKIRSHLSQIHVLNDVEKKELSLLTKQQQEIKKNENNFILGLYSDLPTKNAISEKNEKEIGPSSTEIVSYKNSEDGETSFIRQKWSGGTFCEIKMVPRTVEVEYHCLPNTEDHIAFFKETSLCNYKIIINTWRICDDIAFVPKQKENLINLICSPRGEFTDVDSKLNANEEHDNASGKYLSIMDLVKLVNYESIPVLPKFKPTPVNQQSATSQNNEVFNVFDSVVKLINQKISKDGKGLNEYSEEAKIKFIEDLNSEEVEMFVIDADGVKRKVKKHTPKRAEKKLTAKDYEEFKRKEDDMISEGKANSLEEVIKKKEELINLELLEFKKKYEEELKKLGLDFTEENNEENKEGNAELADNFNSGCNITEAGGDSFMNNPALCFKKGTVSKHLDYLPRVLIILGSVLISFVLLVIDWIKAKRIIKSKDISYSLTSNVTYRYYSIQSYAYFCFFQKVQNSRRTIDILAFYVFFTFKSWKKLFLAELPRQFLYGLFFVENLIQTFQDQKGLKANKMLSQFDLLLLSFKVYFQNISNNPSILAQQCLMLFTVLIWIFSFISFICAILIYFPLLAKIQGNLKEYCCHKIDKRIDGILRKQSKKRVEQARRHELEEIGNMKNGGINFNPDVYSDSDVTSDISNSTRGAKRVPPPLGLSVGPTIPQVREEDFLPHQYSQVPHYNQVQYSQQPLHYNVHGFQAQYHPSSNVNFSQHQPISQYSISSYNGSQQTSQYDRSNFDDRSLLSNPTRNYSKNQFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y364</accession>
    <name>A0AAD5Y364_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005802</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000047">
        <property type="protein sequence ID" value="KAJ3225977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="724"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="757"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="823"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="856"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="889"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="218"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="308"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="505"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="974"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1047"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1220"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1263"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="117"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="282"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="550"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="974"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="989"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1055"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1087"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1113"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1139"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1165"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1220"/>
            <end position="1236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1585" mass="178570" checksum="658D10E9CCED6C6E" modified="2024-05-29" version="1">METASIKLSLPFINNKNYSKNNHLNSNYTSSPTRNISKILNSFSENTAIEKITYNLNQSSHIIHSTQLKSKIIPVSEKMSETIGKPPLDLSYKQNNENFQPKKNSDAHSTSNAIDIVSREKDDRDRIRERDDRSRIYDNRRRGNDHSIDLPNGMDDFDRRPGSSDRFGRSRNPYLDSGRERNFYDRGDFRRHEPYLYDDLNYPSHDDYQRDRYNWERNNYDRNNSSYSRDAFQRPNRYNGPNHHPEHRRNYGNYNSNFRNRRGWVEPDRDLDRKGGMYRRSVSPDRFHERRRSSSFERFNDRRFEGDHSKRYSSVDSNSFSSDSSLGSSRSRRQKNSRSTSASSSGPSRGRSRTRKGDNRINDTKNASKNSSSSRSTPERSANLKKLKKSPSLSPAKDKGKLPLINSPEFNKVENTDTAVKDGNINTSSNNTQSQHPPNDSKIANYHGPKTINQEDCNSSIDIVRASSPLLKITVSPNKIGAILSISENSLPIKEIIPLEKNSKPADIFGESDISSEYGGDFSSDDDGEKKNRGSKTHTARSGSDEDCPSQKSAGSGQENSSDSDTEIAKDKLKKSLKTGSNLDSSKKRRGPGRPPGSKNKHTDDFLDLQQKKLKEYAKKTKSSSGQKILTKKIIRKVKSGDEYTRDETSPFKDRHLRKSPSLDVGKEEGVILLGRKRPLPFSMINDKDRSGRHRLFKHAANNDLESVKALINAGINIHQRDNADCTALHESCLNGHLEIVKCLVQAGADVNSVGDNKDTPLHDACANHHFEVVQFLLENGASTSLRNDDQETPYDVATDKRIIMYLKKWQESLKKVLTKDMNGLTPLHHACANGELGKVKEYINMGANVNGQDNAGWTPLHEASLNGHHEVVEYLLLHGASVDAAGLDGDTALMDAVTNCEYKTVEVLLEFGANVLLKNNAGNDSIQASLNSNNGSSKLRTKIMDLLKRDKSTWLPYRTAEFNPSVIPNEKSTTVDTESLMSRNSSVEIDREKKKKVFRADSVDSEENPRDLTTKGLATWWGASDTTKMSLREERKIQALIRNLEQSEGVSGSSERKRKDKFTDRKKDNSNEDLKYSDNDLTNEGKKKRGPGRPPRRRTDSLDEDDEIGFQKGRDSSPDRKRVKIEDEPALDSSSNIEIKKEHKEKEKITKKKLDVLENSEPNTSKKEGEHKVSSSLAVTIKSPQRKKRKISNLTGYANVNDSNISEKQSVETVKIEKSVVKTEKSEDVNTEKKGGSSSLKPSEKIDFNKVKALNVKNIVVGERKDTSSPSTSKPNIPAIETPSAPVPASVLKKKIKKKKDWTAPVDVKDGQELTASLLGRRDSVPDSLHVSSPTEIKSLESKLLETEEMKLLMLKRLKDVAIYAVSLPDNENVKKTSRYITDMQISLLWGYRKCPDFLEKHPNLIKKVAITSEKQRLERSPLSESVYNLMLLIGINPQYLRTSTNNEGKKGLVLSNYDIHFLKEEEVFKEIEVVYETYKNKLEGELKSFKDFLKIIPLNLENFGDLSDNAVPSTLNNSTVNSVLSKGNSNSSLISISSTVVTEAKSTETVTNIDSSASDGYIHKRFRKNLPPKKKFCQSTTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y394</accession>
    <name>A0AAD5Y394_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TRX2</name>
        <name evidence="6" type="ORF">HK099_005497</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y394"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000245">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="site" description="Deprotonates C-terminal active site Cys" evidence="3">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to redox potential value" evidence="3">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to redox potential value" evidence="3">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="104" mass="11821" checksum="4A598F17963917B2" modified="2024-05-29" version="1">MVQEIKDKEDFEKVLSEHKVVVVDFTATWCGPCKMVAPKFEEMSKKYPDAVFVKVDVDQCQDISQNAGIRAMPTFHIYKEKQRVTEIIGVNVTKLEADLQTALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3R4</accession>
    <name>A0AAD5Y3R4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00027">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="1311"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="221"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="403"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="717"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="896"/>
            <end position="1060"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1466" mass="167172" checksum="30D18352CD4FB753" modified="2024-05-29" version="1">MMNFLTSNSSEITEDDANEIFSPNLLNEEENDLKDNSKEGQADTILALEADLKSRDDSILDLQHLHSAKDENIQELKENLDNLQKYKIETENYLNDLKTKLNFSNDNLIAAKTHFESILSEKDAAIELMNTELIDLKRANYVYQSSEALHNEETAAHCEIINEKEQVIETLKQHHKMEVNNMKTLTEADAKTISELKQSVYALAKQSLEQRFESAALSKNLKCLQIKIQNSEKSIDFVTNERINLQNSVEFLENKVMEFDLINKNLDIEKSELEKKYNDFKTEKEKEVNLANVKETEFLLEKKIYQEEIEKLNAKCEKSQQLKVEAEKNLENSFAQIKELKEVLESQNITIEKLSEVESTLNCKTLEVKKLTCDLEVSNAELRSKSSDITILQEKYLDTEKCLELASKNMELLQNEYEEKHKTLSDEYKCLQSENVALKTTLEQKKNLDIALDEANLKILEGDCLKNTLQQEIENHCSTIKLLEKNLEKLEVDEIAKLISEKNELEKKFTALTESKNAFEASNAAIKTEYSLLQDAQQAAEKECCALQSSLSKISEELLASNCNSKNLLERFNDIQSQLMEVQAINEKNELQLINSSKEKSDLESANTEISEALKLKEIDYEKLLVELKKSTYELSSVKETCSEIDSLLNSEKFLVKKISDEFKNYKDFIGNTIRDLKLDATSLKLYMNTVAHEMKETLATCEEKLKNEAMLLSDINKAVTNEKKEITERLQIKEENLLLLNTKQEETSELLELSKQSLLSERSLLTESKQAFEKLMLETESLREAGNIAKKEILSLQEELKNALEINIKLEKQYLECNELLKGSSAQYDGAIMSKTSLEKENMSHLENLKIISDENITLKKELSEAMHEVAITRKSITECKDMLTTQEKLNINEMDNLKDLNRGLTQSLELAHEKFNNLLSESCKSKEAISQLELKLKDALGSISSFENEKITFLSEKDELQNNLRTKSESCEELNTKLNEAEKEAALSKITTDKDLEILKNEVERLNIEIGSSMKVVDDLNLLIQSKSSELEVKIKNIENLEEELQKFASHNSELITQNEKLIKSTKERKLIQTQQVLIQKEFESEARCIADISDDVNQINADSEKERNTGNVFEELQNTPKDDEIHLQSQEKKKETVSKQIGISKKIKHSATVSSQENSENSDFSCQATLTKSKNTEHANFTSNIKNDGDLTFAKSTPAIRTPFDSFKPPEIIHKKNVVDTSPSSVKQPLQTYTPDKKHNANFKAKPETICTPNQELNSNICVTSDNAVKRNVEALGKEKLDLKKRRKTVSGLLSNHADKATKIEYYICFSGFKEKTLFDSSLKKKLTKQISKLNNAEILPSTTEIDPRTTHLISPAGSRTLKTLSASLMQIWIIYDPEWINQSFINGNFLPENQYGIKNVSSPFQGKKYFLSQSFHNDNLASARKDVYMDYIQKLIVVIGKGEITSNLEDADIILKGSLDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3W4</accession>
    <name>A0AAD5Y3W4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trehalase</fullName>
            <ecNumber evidence="4">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002901</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3W4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF1">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3228396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="634" mass="74419" checksum="33957F5CDF677361" modified="2024-05-29" version="1">MDRVKNNRNFAKSLYQDSEILQLISSSKLYDEDFKSFVDKPLKTDEETVLKNFEELKSRTNNNITQSDLVLFLEENFKQCGHDFVDAELLDFRKNITLFNKIKNKMRNTDGKYEKVLYLSEVLHNSWAGLSRKFENEFNKDDILNYEHNNSSSIYVDHHFIIPGGRFRETYYWDTLFIIEGLLVSELYDTVKGMLLNFLSVIDTYGFFPNGLRIYYLNRSQPPVLCLMFEKYFEKKGYETEEDIALLKKALPILEKEYNWWMKNRSHEVKKGEFLNLYKAENLLPRPEMYPDDLSLIKKANVESEEEKINIFKNLASACESGWDFSSRWIYDYEEKKCSETSVPSEQTECLLSKLETDKILPVDLNTLMLINERIISKFYDILNNKVDPRKFNAVMESQQYKVKSSHFQEQSLLREKLILEFFFCLEDESYFDYHIIHKQLIKRFNLGSFWPLWAEIGFSEPNKDLRYKYMFAPFKNMEKFVASNPGGLPTTLTKDTAQQWDYPNAWPPLQYTTMLSMVSVINKITTSQSNADQANSLNNDQLFHFNDAELSMVDIKSSLRTSLKNLTQIYINSLYIGHRKSGFFHEKFNCEIAGESGGGGEYLPQVGFGWTNGIGLWVIDNFLDTLEDPDYNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTQ0</accession>
    <name>A0AAD5TTQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001389">
        <property type="protein sequence ID" value="KAJ3203715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTQ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="346" mass="38584" checksum="A24175423A631C7B" modified="2024-05-29" version="1">MVKNISNGSNPNDFILIQIINAVGNFFNSRINSTGQDVLVQYALMGIDEILRKKSRKRAEEARKAELEEIDKNNLRSNREFDDSRSNYTVSVKTSRSPSGRQTAPPMGLKIGPTLPNVRLSILPIPDLKLGNYYPENSVVSNANYQYQNYPAFNVGGVHNSFPVEEATLYSQNKNYQNLNALHDYESNFAVQRFGDDTSNNQKNNTYANSMQPQLINHSASLRSPGRSVPYHSVKSNLSDLEQNNYYSNSSQALLEKQQSFPSSSSSDVQKITPSPPKLNNSISSNYNTNNSSAVAFYGQNDYQQLHQFNYGNVKGNNKLKSGSSSSLNYNSNASLDDFHSLSGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTX5</accession>
    <name>A0AAD5TTX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uracil-regulated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">URG1</name>
        <name evidence="4" type="ORF">HK099_001312</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001358">
        <property type="protein sequence ID" value="KAJ3203950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTX5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="3">
        <location>
            <begin position="104"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="2">
        <location>
            <begin position="351"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3203950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="493" mass="54567" checksum="E3B6757BAF1E5BCA" modified="2024-05-29" version="1">MEQALLNLTKEIQGLKTNQTLLLEKVEAYQRETSHEIRQLKAKSSNPGLSQTYDSENESESSFKPSVLSTSPSQSSRFSTSYTGASSATAKRTENVEKQLYNHRIVLTTYPGQVGVSPIPMKWGSADPSIRGPIVVSRHPDSIKLRNAVGAHGGSYSVYRALSIAMRELDPDHKPDLYNTEPVFKFGPHKSWNDPNQIVSLDPFGADIGELFKGQLKKGLDIRPTIAITRAHMRLAEIEDEVKRGLLKVDGKIVCSDAGELMVTKGAIEPVWWLPGVARRFGVEESTLRRALFEDTGGMYPELITRPDLKVFLPPIGGLSIYIFGNPAFLSDPSKKLTVRVHDECNGSAQEGGVGLIVYFRKEGRALGEVTKYLVYNARKRAEGGDTAALYFKRTENVAGVKDMRFQGTMPDVLHYLGITKIDRMISMSNMKYDAIVGSGIKIIERIPIPDGMLPPDSQVEIDAKVASGYFSHNQVVLDLESVKGRAWEDVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUI9</accession>
    <name>A0AAD5TUI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein Sm D3</fullName>
            <shortName evidence="9">Sm-D3</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">snRNP core protein D3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SMD3</name>
        <name evidence="11" type="ORF">HK099_003487</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002281">
        <property type="protein sequence ID" value="KAJ3198719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUI9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01721">
        <property type="entry name" value="Sm_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000002">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034099">
        <property type="entry name" value="SmD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3198719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="97" mass="10735" checksum="218F289311E4B922" modified="2024-05-29" version="1" fragment="single">LLHESSGHIITLELKSGYSYRGKLLDAEDNMNVQLKDITVTSRDGKVSQLDQVYIRGSQVRFFVVPDMLKNAPMFHNKTGATRGRGVGLGKATVMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUW4</accession>
    <name>A0AAD5TUW4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001039">
        <property type="protein sequence ID" value="KAJ3207671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUW4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393:SF0">
        <property type="entry name" value="RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3207671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="267" mass="31662" checksum="6EF3EA828DD1C42E" modified="2024-05-29" version="1">MSDLSIETFELRIEVRPNCDYTFLIENYTSLKQFIKVTRKGLILDYKDKEAIREFTYAILWANFKLRIEIPLNSLCPTIPNRLTYLYWIQEVLLEKEYAKNNAIDIRKCLMGFKFDFLCCNPPFYESQEEILSSRTLKKNEPNAICMGVETEMITTGGEFEFILKLFEESLKFKSNIRWFTSLIGKRENFFCLQNILKNENEIKLLKFSNFKIGKTVRYMIAWSFLLKSEKLVPVKKKDLNPFLKNDLNTENESNTPLQKVKKQKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV60</accession>
    <name>A0AAD5TV60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_000575</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001134">
        <property type="protein sequence ID" value="KAJ3206287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV60"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044189">
        <property type="entry name" value="XPO4/7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596">
        <property type="entry name" value="EXPORTIN 4,7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596:SF2">
        <property type="entry name" value="EXPORTIN-7 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3206287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="220" mass="25775" checksum="A388E95059668D7A" modified="2024-05-29" version="1" fragment="single">MLRWSLVGKYVNFGVFSLYQDPAYDNVINMYFRLLISIPLSDLKTLPKLANSVFLLFQVFSSEQMQALPNIDEQVFSYMLKSSGECLTSSDQVIATQIAMSIESIFSFIVKQRLLKKQHYLVDQVENNINLVNEILVKLMELLFFMDHPSQWTMSRAFFPLVLVSKDFFDYCLRILLQNQLPENQEILASLLKNLMDGIEFNLLSKNRDRFTQQIVQFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVR6</accession>
    <name>A0AAD5TVR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Meiotic recombination protein dmc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DMC1</name>
        <name evidence="12" type="ORF">HK099_000136</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecA family. DMC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001015">
        <property type="protein sequence ID" value="KAJ3208060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000709">
        <property type="term" value="P:meiotic joint molecule formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19514">
        <property type="entry name" value="DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000239">
        <property type="entry name" value="Meiotic recombination protein DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011940">
        <property type="entry name" value="Dmc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02238">
        <property type="entry name" value="recomb_DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF30">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="10">
        <location>
            <begin position="100"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="11">
        <location>
            <begin position="277"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3208060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="340" mass="37325" checksum="91D15FD914185F57" modified="2024-05-29" version="1">MLFEQQVNDDQELELDEEELEIDFVELDKLQDLGINAADITKLKTSGITSVKAVIMTHSRSLMKIKGLSEAKIEKIKEAAGKLIKSDFITGLECAQRRKSVIKISTGSKEFDKLLGGGIQSSSITEAFGEFRTGKTQICHTLCVLAQLPSSMGGGKVAFIDTEGTFRPDRIRAIASRFGVDGETTLQNIAIARAGNSEHQMDLINLIAAKMAEEQNYKLLIIDSVIALFRVDFSGRGELSERQQKLNQMMSRLMKMAEEFNIAVVITNQMTADPGATMTFMADPKKPIGGHVLAHASTTRLYLKKGRAETRIAKLYDSPDVPEGEAVYQISEGGICDAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVS4</accession>
    <name>A0AAD5TVS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000843">
        <property type="protein sequence ID" value="KAJ3211310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051075">
        <property type="entry name" value="SCF_subunit_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872">
        <property type="entry name" value="UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872:SF9">
        <property type="entry name" value="UBIQUITIN-BINDING SDF UBIQUITIN LIGASE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="66"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="209"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="251"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="329"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3211310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="499" mass="57791" checksum="99092B7B368FCC13" modified="2024-05-29" version="1">MDLPIPTSLADDHLKLQQLFITNFENLQSNSLQIHSILKILLQKRNENDFTFLSQVFLNLKNLLKINFIDVLPIHLCVKILGYLDHKSLCRTAQLSKKWNLVSNDDSLWHRMCIQHIDKRCVRCGWCLPLLKRKRKLLDTDLRENDTESHKNKKICQQQTTNETKHTNNETNQHFVSNKKYLMPWKKVFSDRQRIESNWRSRKYVLKTLYGHSAPITCLKLDNDSNILISGSEDTTIRIWDLTKWSLRKVLTGHTDVVTCLQFDSTKLVSGSLDSTLRIWCLNKMECVKIFNHANKITCLHFVDKVLVSGSADFSVSVANLLTGRVFKLNGHTAAVTTVQLIESNRVISSSNDQTLKIWSLDTQEQLLNISSMNCITNFHFDNYKLITHSRFENNLKFFHIFNNKEENFKVLKFKNYILDFWIDKVRLLVLLDGFISVFQISGGSFESEPSSKNAINVEYQQVLELPDFGSKCCLLSDDKVVCGKNDVLIYDFGVNENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW64</accession>
    <name>A0AAD5TW64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008058</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000848">
        <property type="protein sequence ID" value="KAJ3211221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW64"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007740">
        <property type="entry name" value="Ribosomal_mL49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477">
        <property type="entry name" value="MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05046">
        <property type="entry name" value="Img2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3211221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="132" mass="15058" checksum="D63AE7E51BFEF6CF" modified="2024-05-29" version="1">MNNFLFQGKCLAQLKTQVRFKSVIGKVAKPRVVNPPLLTKDLKKIVDLAKAQYVVHRTAKGGWLPIYSEYKHGRTQLTTIIRRIEGNTEALVKDIATIIPGERIKVKENTNHVVIKGNYVEVLRDWFTVQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWD7</accession>
    <name>A0AAD5TWD7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA guanylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CEG1</name>
        <name evidence="13" type="ORF">HK099_007478</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:67012"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.7.7.50"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67013"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.50" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000728">
        <property type="protein sequence ID" value="KAJ3213282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWD7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013846">
        <property type="entry name" value="mRNA_cap_enzyme_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03919">
        <property type="entry name" value="mRNA_cap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01331">
        <property type="entry name" value="mRNA_cap_enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="mRNA capping enzyme adenylation" evidence="11">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA capping enzyme C-terminal" evidence="12">
        <location>
            <begin position="173"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3213282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="292" mass="34294" checksum="79BBFE982E32B330" modified="2024-05-29" version="1" fragment="single">ADGLRVLLFTNIIENQPETFLIDRRNDYYSVNFFLPSPEDIENKFLDNTLLDAEIVIDVEEDNKHTLRLLLFDCIIYESNNLSGKPYTSRLGRLTNFVIGPFKKKLEKDKDYARKLPFQMDLKKLHLSYGLAMVFEEIPKLKHKSDGIIFTSSVGPYVGGTCDKILKWKPSDENTVDFKVEIKGDPNNNPTYNILIWIGGRQHQFFQRLTVDKETQTLFLRKNPHNRVIECRYDPCWEGSWRFVRFRDDKDKANHISVYEKIMTSINDNIEKSDLLNHADIIKAKWKVRNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWK4</accession>
    <name>A0AAD5TWK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional polynucleotide phosphatase/kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001322">
        <property type="protein sequence ID" value="KAJ3204241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000737">
        <property type="entry name" value="Bifunctional polynucleotide phosphatase/kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006551">
        <property type="entry name" value="Polynucleotide_phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01664">
        <property type="entry name" value="DNA-3'-Pase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="47710" checksum="525134AC5005A8AA" modified="2024-05-29" version="1">MLKRKLFQINDSTISKKVKSPWTKKEGELLIGNFRNSESEVVTKTKIAAFDLDHTLTKTKGKHVFHKNADDWEFLYSNVPFKLKKLVEEGHEIVLFSNQTGLEKDGKETSKMKVFKDKVEKVAMALGVDFVIFASLGYGKYRKPLPGMFYEYQELFYNNPEPVDTTNSFFVGDAAGRSYGEIKGKAKKDFSDTDLKFALNLNMCFKTPEQFFLNKNFGKDTIVKEIFDFDPKQLVLDEKPLFLPSNTPLFSDQDILELVIFTGFPGSGKSNFFKKYFESRGYFHCNQDELKSKSKCLQECKRVLSLKQSCVVDNTNPEESTRKQYISIAKVLDIPVRCFYFNSSMELSQHNNIFRSINLNTPRVPTMVYHVFKNKFKEPTLDEGYQEIKVINFLPEFENDDLKKNWLLYHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWS0</accession>
    <name>A0AAD5TWS0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001091">
        <property type="protein sequence ID" value="KAJ3206922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWS0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3206922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="27135" checksum="AB747F5C39849C9A" modified="2024-05-29" version="1">MIIHVGSVCVVNVLVSIAAVYQQSYAIMNPFAAKEVTLSGFMLLPLCTSINIVTTFLVTHFTKDLIAPANNTTSETSTNFSKVSMSNCALLFLASIITAHKFLDDNSYKNKLWSDLNGKLFSCKDINLMERQFLSMLDYNLMVSQEEYDSLNSKLLSTFKLHQQKPLINSTFNIKTNDFYSCNSQNLILPPILSSNSFSRASSYDTLSSSLSSSNLDSDIDDLDELLDSISIGSNNTPNLSHFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWY2</accession>
    <name>A0AAD5TWY2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">E2F-associated phosphoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000687">
        <property type="protein sequence ID" value="KAJ3213684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWY2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019370">
        <property type="entry name" value="E2F-assoc_phosphoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15967">
        <property type="entry name" value="E2F-ASSOCIATED PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15967:SF0">
        <property type="entry name" value="E2F-ASSOCIATED PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10238">
        <property type="entry name" value="Eapp_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="23226" checksum="23B98CD45657D526" modified="2024-05-29" version="1">MIKNNKYKFEFSSEISDGDSYSSADLYSENETDSDCVELSDSSEEELDAKLSLQKTEKLYNSQVDKENETWLINKLKGHCNISGSKSSEKKSISSQKETSATHQSDAQLCCPKCFVTLCLDCQQHEIYKNQFRAMFVENCLIKEDEILKKKKTDNKKISIRTFEDAEEFEIYKPVVCENCELEVAVYDKYEIYHFFNVLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX16</accession>
    <name>A0AAD5TX16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000690">
        <property type="protein sequence ID" value="KAJ3213647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX16"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474:SF1">
        <property type="entry name" value="FUNGAL SPECIFIC TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="79" mass="9247" checksum="56FAA61F39069740" modified="2024-05-29" version="1">MDDITRIKPQLEYKLDEKEESTTELQNKITLDELGPMVVQSDGTMVRITDWQTKTPKEKEQIIRLISKRNKARLESLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXD1</accession>
    <name>A0AAD5TXD1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000697">
        <property type="protein sequence ID" value="KAJ3213569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXD1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031158">
        <property type="entry name" value="GH10_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00591">
        <property type="entry name" value="GH10_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="581" mass="67349" checksum="781C4720B8FFFB64" modified="2024-05-29" version="1">MITSFEDYLDVGSNNGCKKRIDPKSKTCIDIDKNLGSISAIRYSISYVGLENGTIKQYQLHSIKIECKDRGTNDVSFKMMDNKNKQEFKPETSKNLINTTPKLYYDHINGCVTIWNAVTGGLLNIRYDYKTVIRRYFYYKDYLSGACDDGTIRIWNSNVCKAIIKLSDSPVIEMIMMYDYIYVMCNNGYITEIDNKAAYPLLSNKNHPITRYILKNVMLSRMFDSSSVTFCCKCQNEDNCDLSVYLQDDKGLVSDIIYDNISKFIEDYFHKTIDMNYWVPSDSEAIYCGYSKLTLKTKSVLLTKLDDEFTGKKIFNGVRTIFMYIITVVVIDNKLIFESIYEDEPYKRMLNATEKFTYLFMSIIYDSNSNIGIDIKTDGNDLVFTGHKSYSSTMVEFENIIYTCSFEDTTYNINTRYLDKFGDKLYIRVIVADTKDNYITEIDINTNNVIKNYTHALYATSDKFIVSWERKTGEQIYKIGTIDSLYGLNIVNNNIYSNYNTAAFIEKWNMDFTNKEIIEGVTPNGTYWARRQDDLLIFGSHYNYITIFDTVKGTTKMLNYGLNDIVEQYDINRSSDITSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXF9</accession>
    <name>A0AAD5TXF9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1294 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000644">
        <property type="protein sequence ID" value="KAJ3214164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXF9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010718">
        <property type="entry name" value="DUF1294"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06961">
        <property type="entry name" value="DUF1294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="11899" checksum="4412AF2FDC6DE426" modified="2024-05-29" version="1">MILGGGYAVTVNAGSYALFGYDKMQAQAKKWRVPEKTLQFSALLGGWIGGIAAMKQFRHKTVKTEFQRPYYLAVALNVLCIAGGAVAYKFSAPFRLKVKSIMKTRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXK3</accession>
    <name>A0AAD5TXK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001149">
        <property type="protein sequence ID" value="KAJ3206135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXK3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3206135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="643" mass="72412" checksum="B7F5034EC5DFCCB2" modified="2024-05-29" version="1" fragment="single">QSFPQLKTIFSSSNYPRVSHSSSESTLPNFIATVIHSLTSIKTNKIPNRSLVEYIRFILSSTKVSASTIITSLKYLQRLSYQFKIVQGQEWKLYLTSLILSDSFLSDSPFELKCWIKLGGIKGSELAILKTFFLNSISFRLFVDDTEYFGWLSVLEMDLTKFNCNLGFIDNNNKWRAILRCVCCGLMIHYDSVQRNIQQGNARDEHLKNESVHFCTGKDPTKKCKDREALAKFAKTMNLIEVTPVLVSYSISPHQHKNQNPSEKVIKKRKADNTIIKVEEATKLCNVSYDFMRPKMNREGLEWLEEQRRLNLSILISFSLVNNMSSPDLSTHVTDTDSNSVSSPSSSTHYGSNYDALSETTHTSISIDQFLADTSDFYLPLQHNNNSIFNQPLSKNTRKNKMNESADSISLTEIKEEKLDSPVIKSEEDVGSSSSATPISIPVISFSSIDDIQNNVNNIHSNKDNQGETSNSSLTTPVFPFVKISRSASNTAESDHSHDNGLISIKRSSSLPSSYSEVIPDISNEVDLASELPPYVVDAPVMTAKENRISGKVISKDEELSKDSSSNIQFVKTKVNLEDDSELINITDGLKELKVGENEKQQQKKGEKGWKSVTDSLKNMFFSKESSVSLKKIFFFKNFIFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXR5</accession>
    <name>A0AAD5TXR5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000651">
        <property type="protein sequence ID" value="KAJ3214093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXR5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="419" mass="48671" checksum="BCD665CEFDAA30A6" modified="2024-05-29" version="1" fragment="single">MFISAQKNHSIFNKQVSDLKADYDFGVKTYFIESLSTYNDLKGLEKEKNLKKLDFEQFEIENFQENEYSIETDTVPEYRRNSMYPFSKDSSTNLGSINNFNQKEKNTSTSNFENEIIKINDSEVLNLKNYKMEEEIRIFDDEKIVEEKVEENEKLKEVEFKGHKFIPKNNNLKVQEMLMDRRVSSSLLPDINPNSWQSKMRSMSISVSDQGEDRVKGIIALMFAEKLISNDAQRGNEFLDGMKKALSIENSSTLLSSNNGFIFKEEPKLTLKENLIVEEEEEVMEKVNKVEINIQKISEDNPVNVVESVNLTTKNSRTSGVLKKMKKGVRGLAAFKLLNTVKVTNSSLTVGEEEFQIEVESANVEDNVNEETEEEINYIEQEDEETVNYPKARPITPLEKIDVKKNDFYRRRRNIKIWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYB5</accession>
    <name>A0AAD5TYB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001033">
        <property type="protein sequence ID" value="KAJ3207779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYB5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03999">
        <property type="entry name" value="MAP65_ASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="631"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="137"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="647"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="670"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3207779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="725" mass="85519" checksum="C1AE3526966C9F84" modified="2024-05-29" version="1">MLSPLKKSLVPVPSKESRKRTISLNESLVQNFSTNKDLSNSFEPSNQFILEENQNFNNFLDLDLKNNVNTKNNHLVLKDAVNFISNIKQKLNYLEDLYIERIHNDENNFIRLTPLEPVENAIDILIEHEIFQRKSILRLIEQLKKVITEDLLKLKNENNLLEEYYKILEKNVDEDSLNSDNGSTNFISCYRIKKELKNFSQNLKKTIFERSKIVDEFDKKINDALFYLYENPQLIDLNFNKTDEKHLSLENIEILKSKLVLLENEINIRITNISNNISEAYFLYKELKESPTSLQFELTLDFDQKSFVESKVFLSCSKGLADFFLEFEKIKEKNVDLKLIILKLLQVKISSKRNEKFFLNSITEEEMVKRFIQENESSKEENIFTLFLDNIKNFENRIILLNLEINFRKDLIKTIFEEIKLFWKQLKYENDIENEVKFDLEDLSQIIKMKTYADELRFEWKMKMESTVNNLLKVLKELWNKCHVLQSERDTFLTEIESNLYSPLTVNKLEAKIEFFESRFKVWEELFNQIEDRKQFLQKIKDFEVSASNPSRLKGSSIKLLEEEKFRKICLPTLLQKENFLKKNVLKMEMETGTPFIYQNERFLETLENEIENRYIDTSVFLIDNPVNFPAKMSNIPTQQKKRRSLSRTPISKSRSSSVDQSLNKDDKPSNTGSVFNNSSNANSIRKTKSNFNLKISNPSTPNSPSDETGKNTMLARGRTGFRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ20</accession>
    <name>A0AAD5TZ20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000442">
        <property type="protein sequence ID" value="KAJ3217137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ20"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="146"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="327" mass="36603" checksum="8CD0DF32AC40EFE5" modified="2024-05-29" version="1">MFLNVEPNKTASRSVNNLSLQNPSTTLLVPGSSLTASRLEANHSNIHLSATSGLGVDLRNSTIFHTSMRNLRPNSALGNRNLQKSNSGLAASSLRLANISLQNGNGSKLNLYKSSSKLSQMNTSTLDVSGTDNLNELKNNQESISENSYESGIEKEEEEMDILEEEYEALKKMIPDLTENNLFSAKLEKEINKLTNADPLIKIKAMIEIGMLVYVGVNQIDVILYQDRIVIEYIKNILFDEKECYALRLQAAQTISSIIESSVILLDLFRRQFELETILISIILYGNDNEVELLILKDFASNTTIWENWGSNDAKTLLTVFELYEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZB1</accession>
    <name>A0AAD5TZB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WAPL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WAPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000434">
        <property type="protein sequence ID" value="KAJ3217299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZB1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039874">
        <property type="entry name" value="WAPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022771">
        <property type="entry name" value="WAPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012502">
        <property type="entry name" value="WAPL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100:SF13">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07814">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51271">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WAPL" evidence="3">
        <location>
            <begin position="252"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="825" mass="94087" checksum="DA7FECA96BD0876E" modified="2024-05-29" version="1">MKRKTYGKSVKPTLKSFDTTRLAPPKEFLVFNSDEESTDLQVSKNRVKMKVKENSPSKRKSDGGKQPQSSPKRLKDNGSNFVPDNFNEKVENFFLTSPTTRKEISSNSYFDFEDDLAPPKKSCSLTSIDMKKHSKVSKMLKGSKPLDEILVTKKSVEVTLISNLIPEINNSASIPYQHQSFKSLEVVNKSAPHSFTSININPSSHSFRQATYSSSFQKDDDNELESPLEFKLSQESYGSQETYAAFAKRNKKEGLESSDEEKVEIKTIHEIREGGELKIFSDEVDYIFDGLDAQQAINIRRTSSLDLLKKMLKPAFLIKLRAHNFLVRIFLLLSHTNENEEPDSILVVIILLMMISLLNDSASFDHIRCELANWMEKLIEHSFSNNFQDPLINFERNGKFTKLEKRVLKELSNVIATVPQFADNSLIFQNQPSLILSLKVLASFLDYHNENVHIHSSILNNLFNFSENSLVVKYDGFSQQKWLKNCHIDNAMLIIVKKLSEKVHNVLQNWENQLNFNAELAVDLGELNDCFKVLGDLTLFSDDTTFLFASSEETNWWLESVADLVYYCYGISKLNDSCAKEATVTFEYGLRVLMNCTSIMNIECHPNKSFKKLIFSNNNRILKLLLKNIVSNDFFGASSNDQQLEVENVNEIPETLEMNSSRKSYLLCLGIVINVLESYPPKYALCKCVINDCNCPNKENITNLLIKNFKKMKTETVKNDHSVNSAYMAILLSSIINHSDKTYDSIVKDDKLILTVIKTLEEFVAVGELVLESNLERDLNSNVDGNKDQLLVKETAENNNYRTLRTCNEIKRIIACLQELLRPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZV3</accession>
    <name>A0AAD5TZV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000360">
        <property type="protein sequence ID" value="KAJ3218892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZV3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="160" mass="18252" checksum="5F7A0D57D9790115" modified="2024-05-29" version="1">MAVTNWNDPLDDASWNTSTQTTLLFGFLIMLDFLKEEADFAIKKKSCALFYLKVVASIFAIVRNIVAAYISGMWAFSVSDDRAYVAHRVLVMLTWFMTFYMLYFRLKITFIKVEKQVVIGGRVVLVFLFGIAIAECFGCLTMSTVTCWSIFDPAISMGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZX3</accession>
    <name>A0AAD5TZX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000460">
        <property type="protein sequence ID" value="KAJ3216800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZX3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="359" mass="39992" checksum="78E2943FD51D9526" modified="2024-05-29" version="1">MVEIIEEKSTSSTFGVENVKTSNGKSPSKSKGINEKKIGKTLKRIKTLVNPYFLNSPVSTIQISAGFVPSHKLLFHPRLALSPTFQVHRIGTSFLILGHSAYDVFQKSAGIIMWQMPLERAFNAPIKEKKKEESSFNEPANKSILDFKKIQKYLNKNKFLKAQLIAGGTLVTIDLLFYRNPVRINRYYSIFPYSLYPSLEFSMRWLWAATETATSLPVLGIIPVPPIYTPIIVCALGGFRQSEHLLKGLIGALAVGYIMDLRRSDGSRVVDWMKSLGTWWFNFITTKVRKVAGIKVEDSHVEKGDDDNKSDDGENLFSSQFGPIPMEFLSTGLSAIMQLGGIPNSTVFNNASGPSINFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZX9</accession>
    <name>A0AAD5TZX9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000365">
        <property type="protein sequence ID" value="KAJ3218770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZX9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="109" mass="13010" checksum="2EECC6133F1B0194" modified="2024-05-29" version="1">MNLPKNKFKGFDIESDTRNHAPFNLCTKVKSYIINNKEYLNHVKDVYIKETMAIPKVFFILDESKIFDENFWGREMTTFENFGGWDIDVTIGTKELWEEDSRTFWTKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U009</accession>
    <name>A0AAD5U009_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007457</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000722">
        <property type="protein sequence ID" value="KAJ3213331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF105">
        <property type="entry name" value="COPPER RADICAL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041934294" description="WSC domain-containing protein" evidence="3">
        <location>
            <begin position="16"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="36"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="146"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="296"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="405"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="550"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="672"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1130"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1140"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3213331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1541" mass="167934" checksum="8F71292F64C4DBAF" modified="2024-05-29" version="1" fragment="single">MKLTLLAIFSSGVLSSPTQTLQKNSQNLVRKDVSNEYISIGCYTEGKGGRALNGPYIANNAMTVETCQNFCSTAPNKFQFFGLEYGRECYCGSAVANSASETTKCTKPCSGNASQMCGGPSKLNLYSLSGIIPAPPNVIKDNLPSNWKYIGCFLDQSPKLLNTPIFLPKGTNSVKSCIQACSEKKFTFAGLEYGTECYCGNSLTSEQIKSFQKPDTDCSMTCSGNAQELCGAANRLTLYQLSSTSPQPPALTSQPTEIPTIPATSVVTDPAPTVSNPRPPVTEDPPLDPPVPAPNTFVAIGCYSEGNGGRSLTGSSTASDKMTVETCLAFCAGFKFAGLEYSRECFCGNGVSNGGKKQENGCNMKCAGNSNQICGGPSRLSLYSIGGAEPNLPHVVKDASELISGWNYAGCQVQPANGKLLKNVVLTGKTVTVKICIQKCVDLGYNAAGIEYGEECYCDKTTLSVNQWISYAVADTGCSMTCPGDSSQFCGAGNKLSAWVLGTVFEPSVVPTTISPSTLPPTSIATSVVPTSVPATDTVISTPTPEPPSAYTLVGCYTEIEGRAIRGSSLAQDSMTIQMCHSHCQKGKYLIAGLEYGRECYCGNVLYGTSKLTTPEKCAKPCGGDSTQICGNGGHLSLYTVGGVTPDYYKPPAVPTNLPEGWGYEGDLGNLNPTYKSIFEFTGSSGPYQNNNIKGMTVQKCIENCETFGFPYAGVQYGHQCFCGDAIDATAVKSDESQCNVPCTADPTTLCGGGKLSNVFHTKKQLYQWNTIEHPGHYEYLVTSPDIPIMAGLVPYSDKVIMTGRASGGPLNSTHTYEFDYKTLQFRELHEKTEIFCGAGVVLGDNLGRQLTVGGWSVVSLAGVRVFKPSGLKNELQTSDWQEDADILSLQRPRWYPTVVTLANGHIALVGGSISANNDAEPTIEMLPSLGKPPVFVQLLQDSTKLNLYPSAYILPSGLMHLFVGKRSALYETENWTVVRELPECPNHVSGSGGRSNPDTSGYAMLPLQGPDFKAEWIACGGSLGINQDAFETCARIFPEDPNAKWVVERMPMRRVMPNFVSLPDGTFLLLNGAEDGASGFSSARKPVLQAVIYDPSLPSHKRFSYGGKTTITRMYHSGATLLPDGRVLVHGQDPNADQSPEKDPERNFGPERRFEVYFPPYLDSGKTKPTLKLDGSRDLPLGKSFSVTVGKSYNGNVRFNLIRVDVVTHSVYVDQRFIWLDATPTSDTKYAVNVPANPNVAIPGWYLFHAVENGIPSDAIYVRVGGDPFNIHTFPNAFSANGNNQFFDQTNLGPEVNCKELSENEAEKEQQILNDQRIDELFKKKDEKIETIAKAILSILNEFETQKITDDEITININTTFNFKLLDDFIKDNVKDFYLVDAFRSLLINNSNGQETLSTVLNKLVSKYYFEIDDEEMNGQKLRTFSERTSIPKRPRDNLLETLITFNDKIEEIRKELNEVKAGLKSVKKWMAKPFLTTPLEITFKRKLNISSTNEDGLYDLLTNSTEEDVFRFSGIHKASWIQMMQFLSVQPNSRNDITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0J0</accession>
    <name>A0AAD5U0J0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glycosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000853">
        <property type="protein sequence ID" value="KAJ3211151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0J0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051999">
        <property type="term" value="P:mannosyl-inositol phosphorylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051706">
        <property type="entry name" value="Glycosyltransferase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385:SF15">
        <property type="entry name" value="INOSITOL PHOSPHOCERAMIDE MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385">
        <property type="entry name" value="MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3211151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="54353" checksum="A54007520A559C09" modified="2024-05-29" version="1">MIDWLVDKKQRFRHADKCFPDTVLDAWCLISYGERFLPLKTVVFCHKFRLEIFMKNWNISFPTLSTNVIKRYSLVLLILCVLLLIYFVKRKTLVSFNIPSKKNINSNSNQHFTKSSLLNLKEFHSVNNLHLSNSNYKEIGDNFKGSKSKKYKTPADNLNLHIKTQNKKILREEEDYYKRFKNFPNLEWYIARSYLENKYDEQNFFSSNNCASMINKFKEEKKKVEDTIPKIIHQIWITSEHDVDKPLPTFSQVENCKKINNDFKFMFWTNNNISQINLVNKAYFNIWRNTKDEIPGATDILRYEILYQFGGIYMDIDTICVKPFNDLVNKSFFIGYEMFNNTGSVDPTNPMIANGVIGSKKQNFFFYLIKQYFKSKTKKMETAWIETGPAFLTRFLKMFNEKFFKTHEQLEVLDYKKFYPFHHSEANSRIYDQGRELRYGSYCMPTQWGNVKVDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0M1</accession>
    <name>A0AAD5U0M1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_008008</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000836">
        <property type="protein sequence ID" value="KAJ3211412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
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    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1F"/>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="56"/>
            <end position="74"/>
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    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="80"/>
            <end position="99"/>
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    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="111"/>
            <end position="136"/>
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    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="444"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="899"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="941"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1010"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1039"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1122"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1156"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="223"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="593"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="899"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1220"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="831"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="560"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="833"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
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        <source>
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            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3211412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1449" mass="161842" checksum="B14FC8F602873098" modified="2024-05-29" version="1">MLLSLIAKLKSVSKLEKKTPASKPLYFLELLLCLGYSACHAVICVKTILSAQSSSIIISAAFSTLSGLTAFSTLHFQHLYFPGIPSLSTQIYMVLSILLSGNRIRSYMYYGLNISIPINFQMLISSISISAIILFLQHLPSRGYKMKKDETPENSAGLFSILTFFWYNQILYKGFRKGIDSESIWDLPKNLEVTNSYEAFKNKLAKNKSLIRIMFETVRFDYIMLGFCRVAMICFAYLQPLLVKGILSVLDNSPESIEDPQSRSSKALVYGFSLFSATIIFTILSNIYNFGVAKLHVKLHGDLGLMLYDKALLLSAAGKAPDSKILNVMSVDVENCVDCVKIIHDVWSAIAEGIVAIVLLYGELGNSTFSILSMIVLFGLVVLVAAPGIQRSQERYLKFMDKRVSSVSNLLTSILSTKLYSYEDLYLKEINKYRNEELNAHLSFVKYISVMIAFMKSLPELLSLICFLTYAALNPQGLSVSKIFTSMVILGLFKATIAALAGSLSEIISSKVSYERITAYLKVSEVDTSANSVERLPSNEDDDGANVIEFKNCTIKWPKKDNLLLEKEEEEKKKVEKENSKKSKKKIKNEEKIKKEDTTKEKKLEEEVVNFAPVLKNISFQVKKGEILVVLGKVGSGKSALVNAILGEMIMEAKEVAKVRGTTALSSQTPWLLNATIKENIVFGKKFDKNWYEKVISACSLTHDIEILNDGDETLVGDKGLLLSGGQKQRIGLARAVYSNSDIVVFDDPLSAVDVHVGQHIFDNIISNKPESLLKDKTRVFITNAVYHLPDLPSTTKIILLKDEKIYEQGTFADLMNLKGEVYSMYNAVGTGKKKDSDTELKKPEEKREKLTSQVTKLEKSESLLQEILEKKNFNEDSKSGSVSMHVYKFYFKPWKLDGAALSFFIFVLIIAADIASSFWITHYSIQHQKGEETPFGYYFGIYSLLTLLKPIVQYFYVMAIVGYLSRRSSKAILDKSLMGVVGSPMSFFDTTPTGQILNRFSSDAKSLDAQFPMSIINFVVLIGVFITQMSLSSLSNPLLLLGIPVLFTLYAMIQTYYLATSRELTRLESVSKSPIYQSFGETIDGLITIRAFQAESRFREINLSHVIKSQSTTYLTMVGSMWLGVWISFVASLPLLAVILLTVSVSNNTNSSTASFTGLALSVLLPLSSIMVNMVQMYCMLENVAVSVERLKQYTKLKPEGQEEDDKLIESSWPKSGEIVFDDYSVKYRDDSELVLQNLSFRISPGEKIGIIGRTGAGKSSITNALFRIIESASGKILVDNIDISKIPLKELRSRMTIIPQDPYIFPGTLRLNIDPETKYEDFEVWSVLEKIGLKDFVSNSKNKGGLEMELGEDVSLSLGQKQLICLARALLKKSKILILDEATASIDVETDELIQKSLRTELKDCTVLTIAHRLNTIANSDKILVLDKGRVVNFAPPNILKKDELLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Z0</accession>
    <name>A0AAD5U0Z0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PRMT3</name>
        <name evidence="14" type="ORF">HK099_005868</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48096"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11991"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61897"/>
            <dbReference type="EC" id="2.1.1.319"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:48097"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000479">
        <property type="protein sequence ID" value="KAJ3216439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Z0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000034">
        <property type="entry name" value="Protein arginine N-methyltransferase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="12">
        <location>
            <begin position="217"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="13">
        <location>
            <begin position="322"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3216439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="498" mass="57999" checksum="4FEEED35C0BEC14E" modified="2024-05-29" version="1">MIEDNENDSDLEWENEDDACSEEWNDNEMNETGTCSIDVIKNSKKQWVSDEKYLTPVLQDDPLLYCFDENFDKSDTNNVEFEEDEFNLILKKIENLTTESENALKNNDKLLSLELKIKIFEEKEILNQRQYNRLLNDFQDYKNFVKDTFFNTAEKRELKEAEKEEIVNEDGDWEMDSYFGSYAGNEIHEQMLKDVVRTESYRDFIYHNKDIFRDKIVLDVGCGTGILSMFAAKAGASKVFSVDNSTIIKKAKKIVKENNLDHIITFFQGKIEDVILPVQKVDIIISEWMGYFLLFEGMLDSVIYARDTWLAHDGFMAPSNSEILLCAVDDENWINDQYNFWNNVYGFKMNVMKEGFLEEAQVDFAEPSSVISNITSLKKIDMNLDTVKSLDFETNFKLKFDKKGKALALLGWFDIIFSHPKGEEIKFSTGPQTTRTHWKQTAFIFQKGIEVENGTSFEGTFRCVKHPKSNRGLFIEIKFKVYQNGLEKDTFSQNFNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1A7</accession>
    <name>A0AAD5U1A7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">COP9 signalosome complex subunit 3</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">HK099_005200</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000397">
        <property type="protein sequence ID" value="KAJ3218069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061982">
        <property type="term" value="P:meiosis I cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19491">
        <property type="entry name" value="XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000306">
        <property type="entry name" value="IKS protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055089">
        <property type="entry name" value="COP9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047348">
        <property type="entry name" value="XRCC3-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF1">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13481">
        <property type="entry name" value="AAA_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22788">
        <property type="entry name" value="COP9_hel_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="12" id="KW-0736">Signalosome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="180"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 1" evidence="19">
        <location>
            <begin position="436"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="PCI" evidence="20">
        <location>
            <begin position="928"/>
            <end position="1094"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3218069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1166" mass="132572" checksum="97DA559B5B5B548B" modified="2024-05-29" version="1">MSIIPFDNNWQVVLHNKGEVVLYNQIENSLLIKRVRSTNSNFTENPSPASGFNSICSQCGQTIPNPHHEANQSNSGSANSFFADRNYFLLLEGANSALNTAESRTTSNPNFSCSKNISITPISTSPKISEFVTVDEFFQETNLLNQGEGTSIDENIPIPIPIQSGFSNKTLNPGYYERFFIEKVKLGKGFRGSVFCCLHVLNGIVLGEFAIKKVPVGESKDWLVKMLREVKLLEKLRHPNIIEYKHAWVEDYQLTKFGPEIPTLFILMEQANGGNLEEFVELQWKGDTDDSNIIFKKFRGKNNAKGVYPNSASMGRLGGIGYQNVGSLKKVRYLNESEIFSFFLDICKGLVHLHEHGIIHRDLKPNNLLLHYDNDNRELIPKLLISDFGECAILNDIKNRSKNNFGEGLEDRSGTTGTLEFQAPELLIKTNMKYLNLHNASTDIWSLGMILYYLSFSRVPYTQGGFNLGQIYEVTGQSGVGKTQLAVQLCLTSQIPKSRNGLGASVVYMSTEGRFPFKRLESMYEASKKALFLNDFDHICENIILSQSNDFETQLHALKFRLPLLCQKVEIKLLIIDSITGLFRGDDERLLNERSRDLYDFQKELKKLCFTFNLSVIVLNQVTSSFSKNDGVYRNQEEKFYAENSQEKFAFHSNSEEKIIPSLGFIWSHFINNRIVLSKNYLKKEENLENSKKCQPNIIELNCEDYVFREFWLSFSCNLKVELNRRSRFKVEQKGLVIDMQLEALLKLSPTSLSKTLSLTQEESLCQLNANNIDPLQLLKPSEHSLLYLYILNARLKQSQQNPFYLLEAAGRFSENAEKGQLEGKISKVNEFAGTVTRFCSESFNHLAVGILRNLILLIAPSFETLTLIHPLFLRTCILSREFNVSESVIECGIEDLNPSKYQFTVKEFLEYTYYAGICYLGLKKYKEALEYFKMCLSSPAQVPSLIQIESYKKFTLTSLILNGKLEKIPKCTSTAVKNAHQYYNQIYTSLSTLFESKKLNNFKATSSKYEQEFKKDDNWGLVKLCYESLIKQSITRLTQTYLTLSLADIATSVGLGSDLDLTEKIITSMVEDGDIFASISEKEGDMVYFSDSPEKFKTITTTQFLHKDLNYIQELNMKMTTMDRKIALSKNYISKISKNEKSGSTNVSASGVGGFLDDDELYSYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1L5</accession>
    <name>A0AAD5U1L5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000228">
        <property type="protein sequence ID" value="KAJ3221475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1L5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="496"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="60893" checksum="AF908AABFB845F22" modified="2024-05-29" version="1">MKTSNAPTNNFNSVPFSLRNNIMKNAKAPPKSALNQQVALKVQNTPESKKEQNELNELKSKNKTQANEIEKLRSELSTIAQSRGKQDNQLHHMEQQLNARISIKAQQMQQLEQNKLRKQSQEVVLKKLEQEQALKKTKAQEIQTQQKPLVNLNNIKIRDLFHKDNEEHNLMEQNYNYNLFNVINEQIPPNFVAFKPQYGLTRYQNYTAQNLKAPKLTNRPLNASKSKPKGSTNMNVNIDCLPKNVLQNICSYLDSESIKNFSQINSVMRKAFKDLRIDQSKPNSLNINKPNSPNSKKSNSPNSKKLNSPNSKKPNSPSVADNTSSKKENSLNENKKSPKSDNKFWNKEPASNTEKSTFWAINHSSNSKKPEIKIKTNNATSPSTESTFWKTSQPPKSATPAGTPVKENLVVNNMYMYFDPKMFDLPLSYTKSLRPASPVRLFSKNQKLNENKLTSSDQKSGLRSRKSAKPIPEMKIIPHKNNPKAFSRRDGVEPELVLALFLVKIIYVAAFGYGVALAMGYDIGPMVNDFFFNFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1S3</accession>
    <name>A0AAD5U1S3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthamide biosynthesis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DPH3</name>
        <name evidence="9" type="ORF">HK099_005933</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 [3Fe-4S](0)-[protein] + 2 Fe(2+)-[Dph3] + NADH = 2 [4Fe-4S](1+)-[protein] + 2 [Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71239"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:17998"/>
            <dbReference type="Rhea" id="RHEA-COMP:18001"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[3Fe-4S](1+)-[protein] + Fe(2+)-[Dph3] = [3Fe-4S](0)-[protein] + Fe(3+)-[Dph3]</text>
            <dbReference type="Rhea" id="RHEA:71235"/>
            <dbReference type="Rhea" id="RHEA-COMP:17996"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33751"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DPH3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000487">
        <property type="protein sequence ID" value="KAJ3216264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1S3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.660.10:FF:000001">
        <property type="entry name" value="Diphthamide biosynthesis 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF31">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPH-type MB" evidence="8">
        <location>
            <begin position="4"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3216264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="85" mass="9893" checksum="EF6811E37FE8D142" modified="2024-05-29" version="1">MTSFYDEVEIEDMEWNEDLDAFTYPCPCGDKFVIQLDDLKEGEEIARCPSCSLIIRVIYDVEDYLDDDDEELELTNLTNLSIKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1S6</accession>
    <name>A0AAD5U1S6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000324">
        <property type="protein sequence ID" value="KAJ3219868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1S6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="79" mass="8802" checksum="4B5AE58B5FB7DC9C" modified="2024-05-29" version="1" fragment="single">DATAAFDMIHPLDIIENHLPSNFNLGPIDSTTLPAVIKKEVVITKRPPIDSVLNLFDMELIAKKVLTKEAWYNILLTCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1W2</accession>
    <name>A0AAD5U1W2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PHB1</name>
        <name evidence="5" type="ORF">HK099_003224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000214">
        <property type="protein sequence ID" value="KAJ3221701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1W2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041903179" description="Prohibitin" evidence="3">
        <location>
            <begin position="25"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Band 7" evidence="4">
        <location>
            <begin position="29"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="281" mass="31308" checksum="5BE645F10800D9A5" modified="2024-05-29" version="1">MTQHSMKGLELVARWALPLAVVFSGVQYSMYNVEGGKRAVIFDRFSGVSQKVIGEGTHFLVPWLQKPIIFDIRTKPRNISTTTASKDMQMVSLTLRVLSHPDYELLPAIFQKLGEDYEERVLPSIGNEILKGTIAQFTPEELITQRDFISLKIRDDLRKRASEFNIILEDVSITHLTFGKEFTSAVEQKQIAQQDAERARYVVEKAEQEKLAAIIRAEGESKAADLISQSLQKAGPGHIELRRIEAARDIATTLSKARNVTYLPSSTGSGGGSGMLFNLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Y0</accession>
    <name>A0AAD5U1Y0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone-lysine N-methyltransferase set9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SET9</name>
        <name evidence="10" type="ORF">HK099_003288</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000218">
        <property type="protein sequence ID" value="KAJ3221632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10524">
        <property type="entry name" value="SET_Suv4-20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1700">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041938">
        <property type="entry name" value="Hist-Lys_N-MTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="9">
        <location>
            <begin position="188"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1324" mass="152422" checksum="E9E28B5C1169AC8D" modified="2024-05-29" version="1">MFGGKKQTAWRKQSDDLDLENHYLLSLSDLSQYDDICCELLLDTLFLGFKTHKMKSIDSEEKYEIWFTAERQLLAEATIQVLKKRLVPTKELIQGEAQNYKKLEKLCVEDSMNCLLKLFTGEIPFDELEFTYNFNFIFRFTVPCETFIDQISQITHPFKNFLSSLNEKKTQDFKNHFEKYIKMYSPSAGFELARTYRYCNSDKVEACLIATKEWKKGDHMQFCSALGSICALTAEEEQDLENSDFSLIYSTKYNITSLFLGPARFTNHDCNPNFIPSDNGTIRFCVIADINVGEEILLSYGPNYFGYNNGECLCATCELHQKGAFANEFFNSPKRKTSCRTNNFNFRDNVLKVFKKPVVKKIEDGECYSCSVKLTQDQQDNPELLLPSSLFNIRRNQFKKCCSRCYRHFRIFNSLWPDHNQEAKVSLNPIHSLDLHHYVDIPLGVEISDVNIPQIVWVIPQVTNTLYWPAILIPREFCVHEKSLNRLVQKSEQNSIIVLFLSSPPTIGETIKEDIVEFDQSSELFKFFSKHFPSNFNSDVKIALDLINHCKFPTEKKWKTFMPVFDALVKQHPNFIDTSKLEAIPKGQEIGRMQYSEVPGLSVKGVNMFQLVWVNPHKKGIWWSALAVSDEICKKFKLETKEHTNLENSAGRVPLSEMKVFDQHSDPFKFFLNLDPTLINKKNLKNPMDLIQGNLKGKSWSSFQKIFDSYLVFNAAITAAQTCKSSEVEKSPLFSSSLSTVANILKNGESENFESELIKNDDKLVHVDDFENSNEIVVEDSNFDMLEAKTDAQELFCAVKEKTFYTKKIESFLSVPGRSVMNVSDPILVWVDSKKKKVWWPALLIPFDILKKFSVSKELPESAGGFVKLCDCKVFDANEEPFNFFTKIDKDLSKKKAILNVFAFLNGKFPKNNKMWKSYKPVIDYVYQQYFSHVEVDTLSSQNSSSFLQNKENELIEDNKPTDNSKKKKHLRIMDDHVSFPSKRTSDIVDFSERGQCIKNFPDKVSRLHSCIDGTAQEDTQIYNVIEVKETSNTSSNVNVKGIENPKKNPVFSETDMKNSTLNIISDNEEESQITEVSKNSRKRKFPIKETIVSSSKSVSVVPGEKIYDGIFVTFYILTKFNLGKVSQIVWVDSKDDGMWWPAVLITNTITKKYNLYKSSFDKSESKVTVVYLEYPSTGLVDLEDLREFHVDAEPLPYFLNIKPNLLNLPEIKNAIDLKNGKLPSKRMWASWTNIFKEALKSIVQAPIGKKCRTETTRNRLLFSNNNDNDFEKNKKSIEDFKKTDEHINNINLDNFSAKNNFTVNEGCNLEELENVKLALQNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U254</accession>
    <name>A0AAD5U254_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH:ubiquinone oxidoreductase intermediate-associated protein 30 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003312</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CIA30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000219">
        <property type="protein sequence ID" value="KAJ3221616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U254"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010257">
        <property type="term" value="P:NADH dehydrogenase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194:SF18">
        <property type="entry name" value="COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="5">
        <location>
            <begin position="44"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="347" mass="40851" checksum="6FB3646D8CF80C82" modified="2024-05-29" version="1">MSNLRFLTSYFQRSLNYVKDATMEAIRMDMSWKREMPLLSCNSIENLQEWVVGSDADIGGNSEAYWGLTKSKHGIFWGTLSQEIPKGSNIKHSGYAGFRSKERPITMFHRPRFDCERFRYLYMRLKGDNKQWFVNIQTDSLFPTYLYQHRLVFKTPGEWETIMIPFRDFVLTSEGFVQPRQIVMDRSKIRTFGFSVVRQDGDFCLEIDYLKAFNTPNTFGDRDILGAGEYIDEKGNICNIRERDGEEKFKRLYEFSQGENNQMEDINKKKKQIKVIDLESEFKKKIGAGIPFDKIYTGDENKDRLLKKGLPNELTSEIKNKGEDELEKLLQMVLNSKYLFPRYWESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U274</accession>
    <name>A0AAD5U274_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000205">
        <property type="protein sequence ID" value="KAJ3221851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U274"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042289861" evidence="1">
        <location>
            <begin position="19"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="123" mass="14133" checksum="0C8766B0C19252E8" modified="2024-05-29" version="1">MKLHFLILLASIVAIISAEEFTKEEVFCGSYKWKGVFYGVNYENYSEYGCYDIGVTSGKVYPKKMFRSNPKVDKCGVHATNQEDGPDIITTYEPCKGRTVDAHYMFKPKSHKKLGKRFKKDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U368</accession>
    <name>A0AAD5U368_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SANTA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000249">
        <property type="protein sequence ID" value="KAJ3221133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U368"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053090">
        <property type="entry name" value="Centromere_KNL-2_homolog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015216">
        <property type="entry name" value="SANTA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35311">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN KNL-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35311:SF1">
        <property type="entry name" value="PROTEIN EMBRYO DEFECTIVE 1674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09133">
        <property type="entry name" value="SANTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SANTA" evidence="2">
        <location>
            <begin position="40"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="197"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="270" mass="31340" checksum="72E2E6FEA41D551F" modified="2024-05-29" version="1">MNNREKDKTLVDWFLIKRQVKPDQIKPISDYPVKFWLVVCGQQSDGVLWNSSLISTRIDNFTLLTKSNSRYILKGTFNKEKTEKHGFSPEFAQLFCNGFPVNWKEELRKEILIMEGLSDTYDLSKVNTFEKLQTSDSKNQFLSVNKMDVENSTLVRNALTLIVETTRPEFQYTEGLGKVDSSSEAEECELATTPIKIKQKENLLQSLNRRKTKVLDKKKSKDPHRLIEKLESFQNSKIESLQNNLENEVETFETLVTKTFFPILSPKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3F4</accession>
    <name>A0AAD5U3F4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">26S proteasome regulatory subunit 6B homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">26S</name>
        <name evidence="13" type="ORF">HK099_004651</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000335">
        <property type="protein sequence ID" value="KAJ3219574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3F4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000018">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000046">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000033">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 13" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="184"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="16"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3219574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="404" mass="45690" checksum="9846346179775A1E" modified="2024-05-29" version="1">MEELGIKVQQTLVLSKEAQETKNHDLYTTLKTLEQQLEFLELQEEYIKDEQKNLKRELIRAQEEVKRIQSVPLVIGQFLEPIDHQTGIIGSTTGSSYVARILSTIDRELLKPSSSIALHRHSNAVVDVLPPEADSSISMLTDGERPDVSYSDIGGLDIQKQEIREAVELPLTHFDLYKQIGIDPPRGVLLYGPPGTGKTMLVKAVAHHTTASFIRVVGSEFVQKYLGEGPRMVRDVFRLARENSPSIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQTSNVKVIMATNRADTLDPALLRPGRLDRKIEFPTPDRRQKRLIFSTVTSKMNLSEEVDLEDFVSRPDKLSGAEIAAICQEAGMQAVRKNRYVILSKDIEKGYKNNVKKNETELEFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3W0</accession>
    <name>A0AAD5U3W0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">60S ribosomal protein L12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RPL12</name>
        <name evidence="9" type="ORF">HK099_000982</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3W0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06133">
        <property type="entry name" value="ERI-1_3'hExo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051274">
        <property type="entry name" value="3-5_Exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047201">
        <property type="entry name" value="ERI-1_3'hExo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044">
        <property type="entry name" value="3'-5' EXONUCLEASE ERI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044:SF61">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Exonuclease" evidence="8">
        <location>
            <begin position="192"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="401" mass="45313" checksum="358EC5D77AFEA48C" modified="2024-05-29" version="1">MPPKADPSEIKYVILRATGGEVAGGSALAPKIGPLGLSPKKVGEDIAKATKDWKGLRVTVRLVIQNRQATVEILPSASSLVIKALKEVPRDRKKEKNIKHNGNLTLDEVIEIARKMKFKSYARELSGVVREILGTCFSVGCTVDGESPQDISAKVASGNIPFPLASKDEDSSRTFFEDKKKSLKPYEQTYDYFMVLDFEATCCDRDKRFVNEIIEFPIVVLDGRNGVKVQQFREYVRPTKNKVLTEFCINLTGIQQETVDEAALFPQVFNSAKNFYNKFHNENPCSRSIFVTCGDWDLKSMLPRQAKNSNVKVPVYFQEWINIKTPFKLYLANSKIKNNKRLGMPTMLKTFGLPLIGRHHSGLDDCRNICNITYKLIQNGILLEKTGEWSQELKEELSEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Z2</accession>
    <name>A0AAD5U3Z2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Z2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="345" mass="36777" checksum="72704E9EDFA30391" modified="2024-05-29" version="1">MDKQNFDHKTHKLCINFSAKISLEVYLKPAVLAVEKSDPVNFFSFVKNFVICSKHLKPHSDSEAQNCTDFVETEYADFAEAATDYQTGLGKKCDFLLHKKFERIVVAAYLGSNSDFADKLLALVASVNKIFVVETVLDFEDVVGRADFAADGLIIVGTVHTFRILAHYSVDNAGSVVVADEWVVVAFADSDIAVNSVADGDCVNPPYLAAAGDDSEYFFALPVGNRVVLDVDFDFVDSDGTVDFDVVDAVVDFDVVVGFGDVVDVVVGFGDVVGVVVGFGDVVDVLVGQAVVVGFAVADFESVFDFGVGSAVVVDFVAVDFDVAVGFAVDFAVDIDVAAGFGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U431</accession>
    <name>A0AAD5U431_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U431"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="517"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="545"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="696" mass="78500" checksum="8E6FFEDAF7AA37FD" modified="2024-05-29" version="1" fragment="single">MNDADANNSTNLLFNCVTALEALYENLTKLEKYPNANISQLLDGGDFQNHLSYVTTRMHFLKKATSSQGANYSNNQYNWSEREVLKREYPVGPNDSSSFYKHNSSTSHCDLQQNSIGSEQDYAVRHPPCDTQEIEQIGNSSGQHTVNEMIIDDSLLQNIANKFPPNDTISQEIAPIRNNFMVIRDTMSESFGDNGPELELKIGDKIFADGWGDDKKNFGFGRNERTGAEGIFNLSYITFSNPVEATSSASSSPKLVADEDAPSDALTRLLQKKTERVTSTSSNLNVYPNYNSLSPPVPAKPIVKSDNSLMATLFSTFHSQEATDINTLKRTGQDIPFERQMNVVTQITETMKGIPTAERIAVAGENSNDDSIILNRRQTEPMAKENSPLPNPKRSDSDPVQLNKKDNEVYFALTELIEMEENFCRQLGYVIKHILDAPLPDSIQQYSFQIKSVFKGFKELHAHSSAITESFKLARDGHYAKMGGKELTGVYAVASVFAQFIFEFLIFPKYVADYLLPIRHVPRYPLILSRLRKISDKDHPHFKILDVAEQFVVQLANKMDQVEAEEDQMLKMFEICTKEITNCPQSIISHKRQFLATFKIVIREILLPQLADNNIDGHQKSLDNYYASNIDGHIANPRTAKVPSGSVSSPFFSKIYLFSDLIIFSNFIKETNKNIFSKRVDIGNFLKCEKVDTELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4C2</accession>
    <name>A0AAD5U4C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Manganese lipoxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002547</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000185">
        <property type="protein sequence ID" value="KAJ3222234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4C2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043651">
        <property type="term" value="P:linoleic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034440">
        <property type="term" value="P:lipid oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042248680" description="Manganese lipoxygenase" evidence="5">
        <location>
            <begin position="18"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoxygenase" evidence="6">
        <location>
            <begin position="157"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="562" mass="61560" checksum="F6298AE2572D9E7C" modified="2024-05-29" version="1">MIAKVAKLIFLIGLAASQIDTLSLPQNSPNVTARSENLAVLKGQIANGPRLHVIANDPTKVFQFSNGPVVNAFVGAMIQTEVADINSRSTKDTQNFIAGIILQGSASISTLDDLSNLFNTFSSKIRFPPSLVNWQLDSSFASDQLTWCGVGLQLSTNNEFALDDNLVRSITGLSMKTLLSRKKLFRVDYSNIKKYSKINVGQFTPGAIGLFYESSTEDFLPLAIKVIDNAIVYTPKDQADHWMFAKLAFGAAESNFLPTEHFITNHIAIEPIRVELMRHVSVEHPVSALLNHHFTNIFGVSAIGQKVLIQNGTTFDTIFGIGAKGGAQFMHDKSLNYNFQKQKIVQNFADLGVSRNPRNYKYRDDLLSIHSAVGKFVKTHIDNYYKSNKEIVNDAEIQAWAAATADPNQGGVKGFDAAFKTKDALIDTVANLITIVTAQHNILNGASTWDGQIFPAKPNALYGAVPKSKDEVINARSFLAPSKQLIAGEIALHSAFLVAVPESHLLGKSYASVDLGKFSAPAIASFQKDLNNISKFIQARESKSTRPFTVLDPIQLPFNVWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4F7</accession>
    <name>A0AAD5U4F7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_003801</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000254">
        <property type="protein sequence ID" value="KAJ3221063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18034">
        <property type="entry name" value="DEXHc_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000004">
        <property type="entry name" value="Endoribonuclease dicer-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="25"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="397"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="12">
        <location>
            <begin position="1340"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="12">
        <location>
            <begin position="1558"/>
            <end position="1711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00035116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3221063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1834" mass="208611" checksum="3865B7D72F23A028" modified="2024-05-29" version="1">MNEKELKEKEMVKKRETPRPYQIQLFEMAIGSNVIAYLDTGAGKTLVSILLMDHFSQPLIQIDMNEHFNSIRDKTNLNLIEINPDVLRQSLSQPQPKKIVFLVPTILLVSQQASKVKMNTNLEVGEYTSEEVSSVSSWDAVGWLNEFSKRNVFIMTPQIFLNLLRHGFIVLKRDISLLIFDECHHAFGNHPYNHIMQEFYHTLPTNQRPKVFGMTASPIYQNIVTHTDSKAKLTELQANLDSKIITVENRNSMKNFIAKPKEIIVEYEPSTCSVENLEAATSNNVSLSAKYFKYHRSLLLKRKAELEIITKNAPESKDETANKELMKIKKCILINEQIVVELGAFCGGLAAELYSKDFKLKSNIISNLVEDQTITENQAIVSCPSIHEILPDDLSPKLNLLFKLLRERDLRCESVSDFSGIVFVDRRITADIISKAINYFSAHLFSKVLSTSAVGGGNGKKREVHNFKNEKKKGLDDFREGKANLVVATRVAEEGVDVYDPACRLVVIFDLLRSSSGYVQSRGRARHLLGSEYIIMIRRDDSAALQSLSKARMAELMTRNISTSGELESISDSLKIRARDSEIISGLVGELKDSSDLVTKIGATAAPNSAGEFLARYFGAWNNFLTKKFQKLPSLCKITNCNWSPTKGNENFSFLVFQLKDSDEEAKESFVECTKMQKVIVDEEANHTEDNTSMADYGYVYCLLVPVTSSLQSFISTVKESVPKIVKEKLNCLSQTDVSFLPIFGSVRFTKKSAFQSASFEAIKLLYKLGALNEHLLIAFQPNSAADSEEKLYQKKGSTFSAKKIILANQDKLLFYLLKTSTNSDIADVPGEAKYKHQLSSVLTINTEWDQKYLYSVASPLSTKHLIPLYVTILSFGPEYEVYGRDCNPPVCPTYHLFNSPLFPTQLPEDWNNFYYFPTYSSFVSSTKEPRKSFAILSKKAIPSKDIPPFLIQLSEKVACKVKCLNWIETYDEEQGERDCYRPVEFSEDEFAKILNFQEKFWDFCLAPNKNLPKLDQNLKKKNIQQSPYFLLPMSGSPILFQKKNETVETFNADLLFSHLKAKETKTYTFEELLDPPFCHWYIDWETVNHTTSASRISLSKWVNEITAITVNLCDDYEAQKGRKRKIDVVLQDAVEDASLLHNRNQFNFEIEAQTEDDYQDLMSIDESSKIENSKTDFFSFYNRESSFTTLYNKILSTKEKNVYKLLKKKNINKNIIVKVDEILFQTLCIGKHNKIPYLLSKVLYDRHPTDTFSLKSENDKLISFVDYYKNKELEVKDLEASLIQARLCGYISNWNPKQPSPLNVKEVELVPEFFDVIPFSSELFHLSQAFPSILHEVEMYTLVDDFRLSMQLPLVTNSTLFTAFSATSAGNSSNYERLENLGDSFLKFAVTLDVYRKNPQASEGEMNVKRVAVISNSNLYNIAIKCGFEKILFVYPFNAKHFTPPGRKNLLIEEDSLLKIIGKKPLADCVEALIGAYYVDGGQDIALKFMHKIELVSDTVDEKVCTKEYAIDTHKDDSIKVKITDRVSEITMTTLTESVLPIKYNVSGSVYKFPFSLKTLEIILNYQFKNKNLAIEAFLHPSFQTGVSYQQLEFLGDAVLDWVLTRFLYNSNANSSPGDLSVLRQAIVCNESLAWLSISLGLNKLLLSKSQSLEQCISSFVTYHFQNENSATNDLEQEGEETMKDFELEAPKVLGDIFESCAGAVFVDCGYSLEIFWNVFKPLMINFITKFTDPKVLCKSPIRIFCEFVQKFGFSITRDLIFNFQISENKVFCEVRMFQSTINVLLGTGNGNTKHSAKKQACFNCLEDIKKNSSPLVTDIDKLVLELKKNIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4P3</accession>
    <name>A0AAD5U4P3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000170">
        <property type="protein sequence ID" value="KAJ3222558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4P3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043596">
        <property type="entry name" value="CFAP53/TCHP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31183:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31183">
        <property type="entry name" value="TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="77"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="408" mass="48345" checksum="328248AA9A1231CF" modified="2024-05-29" version="1">MKIKYNNLIEQRRKDDEKRGKIIETTNYYKISDNKSKFEVDTTNAIKRNHIRRRFRELKAEEEGKLIERRLKLRELLQRDEEQYRKELIVKEETKEERIERMRSRMVELKEKREAERKAVVEEQLLRKWRSECNELKQVESRLNEKRVAAARDIQLQEQELKKKLALEVRHLRKSHNELKPILSEQDLIKMRNGKTLQDLKTEQENFQLEENLDNCAATDTKTLFKLKIDHEKNNNINSTSIKTPPASPKVETFSSPTEFNYNGGLFDNEFVNLLDHNLLDFNFDQVLVDPNIKVNTSSYVRSLYPSPPIVSLQDFPKEKNIFDFEFTKNSTNNQQVYPFATKIPAATIINNNFEENKFAFDDNEFLNLGEFFPTSDVQFNELIVSDYYPPTPSWDTFLPSITNNDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4X9</accession>
    <name>A0AAD5U4X9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003542</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000231">
        <property type="protein sequence ID" value="KAJ3221420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4X9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF139">
        <property type="entry name" value="PAIR-RULE PROTEIN ODD-PAIRED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="226"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="29692" checksum="2BFA38F5472E04A9" modified="2024-05-29" version="1">MNSANTLILLQERENPFNMRNILSEELAVPKMSPSSPTPSNYSNSSFLSSSTLSQQEQFKEIKEKNTPYFINDMGMIEIFQTSEMRDPYKQKQQNSLKKNPSKTMIHDSVFQVLNQMKNCQDKGNVNVTITLGQLSQILKVGKNLNHKDQEELNNDGDTNDTNIDNKNVDIVKSLINLNPNVNQSVGGGKIKGGKLECQTCGRTFNRKFNLKVHEETHSTTRERKFCCPVEGCDKKFFRSHELMRHNQVHLKKEQKHASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U575</accession>
    <name>A0AAD5U575_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4614 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U575"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040120">
        <property type="entry name" value="C19orf44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027884">
        <property type="entry name" value="DUF4614"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22409">
        <property type="entry name" value="CHROMOSOME 19 OPEN READING FRAME 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22409:SF2">
        <property type="entry name" value="CHROMOSOME 19 OPEN READING FRAME 44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15391">
        <property type="entry name" value="DUF4614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4614" evidence="2">
        <location>
            <begin position="554"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="738" mass="83833" checksum="0699035400A6B94F" modified="2024-05-29" version="1">MKRFEFNNEIEDDVSSSDKKNTFLKKPSILDRAKSHLKGDNKWKENSVKRDTTNGSQKNFKSTSSVESDSDEELKQFLSKLGNREQNSSNVNSASSSPIKQQNSYLKTPSSSPVKKEVSPAKAASPYLKKTIDLTEGKSTENKIVNISPSLLQPKKSFTIIPKHDEDLNSSTASSRKKKTSAHLKNNKRFFTESKEDVDLSEESSDSSLGSDFEAFIKSKGVVDFNEKLVEKSTEYQLNDEIEKNVNTLKKSDAIHNIGEKKVELLINHETVSSAPKGKSKVDDTTIFNTQMEVCSNSDSEDEAIITKPALKKNNGFDLKNETKVKLLQNKILTISDLFPDSEEHTSNETLPKTAMQETPKKILFEAKQDSISENVLIEEKKQEAKGSPMKIDPDIDLKTNQREQPYNRVNQYSPIPDMHGTAQSCNVQPNFQLNPQPNFQPNFQQNFQPHLQCNNPSYNQPSTPNIQLNTPYSYPLAHTEQYSFKYPEVPQQLNYNDNYGQKAFNVPNQPQFFNPFQSPASNFLSQFQPPYLNLPQFPVPQQAWMQQSFKSPSESKKIETKSKKERNSRESEYECSDFEVDEISEILDFSSSNSNDLRNNSRDNERQGSSTIGSDFAPSISSGLKNVDNTILDSINPLSSVHNQQYLNTNIPLNDTLHKLTTIQNPNQLILNELFLGQIKLIEQFVEICKRLAVSESRNSRSNYKYIKLEDVQKYIRENKKATLTMDEALEQIRLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5K4</accession>
    <name>A0AAD5U5K4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000069">
        <property type="protein sequence ID" value="KAJ3225162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5K4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="258" mass="30209" checksum="3471C4DE7B9A5195" modified="2024-05-29" version="1">MNQPDSIFHSNFEELKLDLKNLRKIETYCLLGETLQTKAFFSLVNLCENLVDLTIPFPNWESIQILKKNLMKLENLNIVNGEENFAEEEEIHLHEQDENKNFEICLNLILKNSLNLKSFTLNSSKYLTEKNLKLFSEVNFKNLISLELLISNFGLEFKSFKTYLLKFVGGGLVRILLDLRNFLMNDEMLIDFSFYLPKIVHFEIWTSDASSVTLKGAKSLIEKCANLRRIHDCGFSEEVKSYFMKNRVDCRSFMMEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6A8</accession>
    <name>A0AAD5U6A8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GRX2</name>
        <name evidence="3" type="ORF">HK099_003369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000221">
        <property type="protein sequence ID" value="KAJ3221582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1074"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1324" mass="151011" checksum="D5E7E07A84BBD241" modified="2024-05-29" version="1">MFCCHWVGCGATNFETENTLYHHCLQNHIRQGKQVCMMKPYSSKPFCNAQLRHKGQALDHIVTHFSFNLKPIPCSFCEVHFRNRQDKKKHETLHHAQDLKPEEQDKNNAVTLKKLNSNVVENEVIKTQESAVFLEDIAEISSQESEIYTPQLKTQIYNIANAAIAKIPEFDKIDLEDTSETFLTKGVEVFDFMSFANVIYLATNTISDSTRWDKMFLFFRDKGGYIPHKIIEDFYFSTTKKNRFLEKKCYILAKNYFEFKCLGLRPLFVKSFLDTILKLTEKLTTEAQLKLGSFFIQSEQERLEDFQDRFLGGKLQNSFKELTIDIAIRIKKILHYFKNDSVMELVELKNENKDSFCGFFSIGIKISYALGDFYKEYQRLFLNNTVKICVVEFDKMVREMIWGEDGKMIRLLCCGGINCHVSDSSVSRGNIYLSSHEQADIIWIKSGVNAEQKASHEMNKTHHRKEREKKRLSVSTTSCALSTSQIKKLNSPTGSVSSQLSNVGVGRRGSSDTYMSRVSSNSIPYSSKSSKHNCLACQLKEQNQKSYLKQTASTITKTKKKWLPPGNVPPSQILIDTTLFTTSTKPSNTYIWKPFYRSKKEDVGYLQSKAEFNAKFKKVSKDSLKSNSNFKIHKNNNSNIYIQEVHEEIVEYCSIHQEKNESFKVNYIVEQNNSYDDLNSDVGSDSTFHDREIEEIVLNVGQLELLTTDAFEEKKEIKSSEQEELEGDNTSTFINQEHNCKAERLDSTFNLISGMDFESDDLMKTNYTHDIADDVVLSEVDEVQRNINLLLLSQEDCGEIELSKIATETTDGFLERIYSLEVGEVDDKISLKGTGIENERSISIVTQPSTENLQPQVDHIIDDEKFMELSNVSVPANEESSELQLHKKLSIPYLNSSDFKTENSYSNEVIFGDEKTLIDISAENSSSNSISSAIHNDAENNLIATNCETNHTNKNLNNELNDIDNIEQNIIDNKKEKNVPLQEDTLNPSPQLIFNKVTQSKQKQPSQFRNFMSRIVNFVDTVVKPEKVLETTNKETENNLSGTVESVFQKNCENILNTDKSDSGNNPDKKDFFKSQKNSSESQLIESSNIGSLYGKFGASFNQGERPILIRRKITIDPFGNESVVDTEEELTEEMNLSDGEFETVEVGGKVVSKIVRRVIFKQESTENLCEYKKLEAKSKELENSFVIKRRIIKRTVSVNEIGEEEVCETEHFDDDVNDSLVTKRRIIHVNESGKEIKISEEDSANGDFSSNGTNSMLKNFVHLEKIVELDQIEDGNEIQNYLASKTGQRSIPNNFISGKHVGGNDTLQILKDTGELQKLISKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6J4</accession>
    <name>A0AAD5U6J4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 79 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6J4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052974">
        <property type="entry name" value="GH79_Enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183">
        <property type="entry name" value="BETA-GLUCURONIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36183:SF2">
        <property type="entry name" value="BETA-GLUCURONIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041980028" description="Glycoside hydrolase family 79 protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="38410" checksum="A16F328E52FFD7AC" modified="2024-05-29" version="1">MKFSIYLFLIVSGLSQVIDLTLQIPSASISSFHQGFAIEWAGIKQFFMKKPSGVRSIDPEEATVDDLNLAAIQLVTNLANLTPENSEKTKLLIRWWIPSAAGPWEPALTKVVPIGPYSLKLLDLVANVTGVKFSIGLSMRSNNITNNYQPEFLNAIKDIITPSNIQSFELGNEPDLYAKNGFRSPSYTPQEFFKENQGYIDFVKSSYPNADFTGPSYAYPWDEIYLPQYIKTFAGQMSYFSFHHYELRGCATNVTLEQLMLEPIDATAYKFYSAAVQALKETGKPGKVIWNEGGTVSCSGEKGISDAFAAALWTLDSGYLSALLEVNHQLLAGINKYIKLLILFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6L9</accession>
    <name>A0AAD5U6L9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartokinase</fullName>
            <ecNumber evidence="7">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HOM3</name>
        <name evidence="9" type="ORF">HK099_007742</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-aspartate + ATP = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6L9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009090">
        <property type="term" value="P:homoserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04892">
        <property type="entry name" value="ACT_AK-like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2130.10:FF:000001">
        <property type="entry name" value="Bifunctional aspartokinase/homoserine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054352">
        <property type="entry name" value="ACT_Aspartokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21499">
        <property type="entry name" value="ASPARTATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21499:SF59">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22468">
        <property type="entry name" value="ACT_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="8">
        <location>
            <begin position="413"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="473" mass="51853" checksum="1809CE25CA6D5E4F" modified="2024-05-29" version="1">MQRELVIAKFGGTSVGTAERLLHVASIVQKQNEVSSIVIVLSAMSSSVKKLGTTQQLLSAAEHVLIPNSTQYIDIINDIERDHLNVVDCAIKNSDIKAGLSQRIKMDCEKLRGEKLSARIMAGVLMDKGVNSIYLSLENLIDRKLFNSNQIDQKFYDHIVDRLKSIFQSEEYDLKKPVVPVVTGFIGQVPGSLLTTIGRGYTDLTAALIAVALSAAELQIFKEVDGIFSADPRKVPLAKLLNTISPEEAAELTYYGSEVIHPFTMEQVIRAKIPIRIKNTFNPDGAGTLILPNKSLENAIPGTENNNPSKMIALHATAATIKDEITVLNIHSNKKSHSHGFFSNIFQTLDRYLEIKGTFFNNFFRFGIIVDLISTSEVHISMALSKPPIEEAQTALSKFGNLTIIKNCAIISLVGKDMLSMVGIASRMFKVLSTFGVNIEMISQGASEINISCVVEGDKGDLALRVVHDECCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6N0</accession>
    <name>A0AAD5U6N0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WIBG Mago-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6N0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903259">
        <property type="term" value="P:exon-exon junction complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039333">
        <property type="entry name" value="PYM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015362">
        <property type="entry name" value="WIBG_mago-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036348">
        <property type="entry name" value="WIBG_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959:SF0">
        <property type="entry name" value="PARTNER OF Y14 AND MAGO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959">
        <property type="entry name" value="PYM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09282">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01273">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101931">
        <property type="entry name" value="Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WIBG Mago-binding" evidence="2">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="210" mass="24322" checksum="F5842519376F2EAF" modified="2024-05-29" version="1">MIKNKQSASGIVELVNTPMGVERIIPPSYRPDGTIRKAQKVRPGFVPQEDIELYRPGARRQQKVISKETSKEDDQISSITQTLNATYISNNLVNTASNNEPKSKNQKRNEKKREKRLLDEVNNLLENKNDGQQRIIKGNENESKENTSVEYEKRIKALKKKLKQIQELELKITNNENYEIDLDQKEKLSKKSDFENELIEIEKLLKKITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7V7</accession>
    <name>A0AAD5U7V7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008423</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000092">
        <property type="protein sequence ID" value="KAJ3224473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7V7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040091">
        <property type="entry name" value="LRRC56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22708">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22708:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="437" mass="50734" checksum="FBCA0DA90557C499" modified="2024-05-29" version="1">MDFDEYFKERNPSLLTPQEELSKILQFHLSEKKLRQIVGEEDLDNVKNLKLKKIDCRYSSVSWLSLTIKNLRELQFKDGFIPNIREIGSGFKYLTTLKLIACELVELDGIGNISKLKEVHLPFNYIKELSPLAFLEDLEVLDLVGNLIEDIEEVENLTLCKNLKKLNLKENPITTNKKNVTSMSILNNLEKFKIYLNLELLESFDFEFNYDISNESRIEKKISDDGKISEVKQMEDAGRPSSARSSWHTRSRSNNYIPEKFSDTGSEFTFGTNQIMQGNPVLFLKHFKKKNSELLQTSKGHISQEKNIGVKNFVQDNYHQEKGEENSPKNLINSKRKLKKTSTINLKEDFEILNITKFEEKCYNPEKILFLNERPASSEFEEKKNVNNERIYFNRKKIFLKGNNKIDKTKEAIDVEDLNNSSCSSNSSIRVESCGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U810</accession>
    <name>A0AAD5U810_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007319</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12257">
        <property type="entry name" value="RRM1_RBM26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007557">
        <property type="entry name" value="PSP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045137">
        <property type="entry name" value="RBM26/27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041131">
        <property type="entry name" value="RicT_YaaT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398">
        <property type="entry name" value="RNA RECOGNITION RRM/RNP DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN SWM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04468">
        <property type="entry name" value="PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51411">
        <property type="entry name" value="PSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PSP1 C-terminal" evidence="6">
        <location>
            <begin position="588"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="1379"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="2">
        <location>
            <begin position="1379"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1096"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1196"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1868"/>
            <end position="1907"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="737"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1613"/>
            <end position="1671"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1697"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1196"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1220"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1233"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1272"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1304"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1890"/>
            <end position="1901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3228038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1907" mass="216969" checksum="B74F88BAB10DC90F" modified="2024-05-29" version="1">MLSPHLIYRIDRALLYSSKLLVERRYIENCSADPNEILELILKKKLFYKKNSNNLLELRKAESIVLKKSILSICSSFRLQNELNSRAATKYDPTNKSHEKKLLEFWDLIKPNEALRSKISEQWISIGFQGSDPSTDFRGMVPLTPPLSDQVPSSSASPANNTIAIPTEEKSSPTMKNVSLVDNWKAVGSPPRKLSIANVEDPVVEERTRRTPTPTASSTANTNPKHEEDANWNKMGMQWGNGGNSIWNDNSVATKALAPPAEDDDHKRRLSLKPESLIPGQQGARKFTLNTQSEEVEYEQLKEESDSYAKYVPPPKARSRSKSSSAIFGLLSQENIPSVSITDMHNDDANKNIWVHDGRRESMQSSMHRRSSTQPSGYNGMWENNVEDEDTLGIPGTHLNNFRLHERRFSHAPVLSNDYAQQLLSTSSDVGEDYPTSMDMRRRHSLAGPLYASGASGRYLADALENINIDDINDAPSYNDIDDYFENTEHRTRAWVEAGKNLQMQSFSQHWPLYVVEFKAGRHDYFFVEDPSMVVKKGDLAIVEADRGKDLGKVIYDNIQNMQQLQLYQANHIDLLAESQFGKDVHPKRIYRLAVPTEVALLVSKSQDEAKAMSICQVKIRQKKLPMEVVDAEYQWDRRKLTLYFVADRRIDFRELVRDLFKIYKTRIWMCAVNPLKIGSLSMSGPTGTGVNLNMGGFMEQKVVKLSGKKGTRMKSATSSSTIAKNSILTQATHFFKKNSLSKKLDKENQIKELQEKRKEHENLIKTLSSYCNEDFGSKYNTAKVYGNNNTPGEGDGCNGNFILMRSFSNHNASSILEYKIDSVILKKKEVSSNSKPLTNNCNNKGTIKKSENKNLSNLLGGLSLESSFLARNSIRSIENRESVVNSTETVSTTLNNSFNDSCVSSYKRVSILISWESNLDFSFKEEKVSDYKNSLGKKNKGITLNFLLKKIESQPLVDPFQELDEAKLKTLNFEELEDEEFKNLKEIDTLLEEKVNCNFKKKEIKSTVDILDPIHPLKKNFISNEKIEDLKLEIELIKCWRNPNYPNDYDYEKKESKFLKKEKRKLLIEMEMKNRIEKLKGPSYYNQPKEVGLSNVDSLEQREESEYSAGSNSKRLRADSHEEKVQEINLDLSGEEACDADPSVLAEYAIALLRHEKSISELKILCLNQLEDFLKHETENFVKELFQLLESDDNFNSSIRNNEDQNTLTIKAEEEDSKSSNNSRRASSPLGESRDREDDRFINENNRERDKDRKRKSHDDYVHSQKKSRNNTESSNGNQGSMNYNAGNKSGYRGNERGNFNSQKSQQHYNKQQQQQFFHQQQMQQQQIQQNFGNFPNQMGFHTTWNQNQVSRGMAVRSFMPNINPFQQMHGRPVTAGAGRQQRCRDYDEKGFCLRGDLCPYDHGADRIVVDNNPMMMGNVSFGMQGNQAAPKLAINAFGGTRTTLPLPGSYDPEAAGRPSLPTVSTMSNILGSNSSMQLTEKFKKKKNTQPPHLVIEKIPLPFCTLGKIHEYFKQFGQVKNIHLTPSMHRAIIEYQQLSEAQSCYNSPVAIFGNRFVKVYWYREEHSDISVSLAPTISLYPKGQEPTFEVTPEVKCPPDTKSITTTSSKPLNTEEKKKFELQEAQKKIAEQQKQQTLLLEKHLENQKFMLNQLKNSKNLTTSEKEEIKKKLAEFTNLSSEMLSSSFSETTTFAGNIKNLGKSKEELEKLKLEKETKTKLDRELENMVIDKGHNSNAENESADPALVAALDSLKKQAINLGMNPDVITSANNPTVTNTYSHFRGRGRGIHHRGRGTSFWRGGRGGIAVSPRSFKLDNRPAILFVKGAPFNSLEALKTHFEAMRLGRKFQDILLFLSWTRSFVEPVQGKMASGTTESEENNLEENLKNSDEGNDEEYDDEEEGRGWKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9C8</accession>
    <name>A0AAD5U9C8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Anoctamin-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ANO7_2</name>
        <name evidence="11" type="ORF">HK099_006048</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9C8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032394">
        <property type="entry name" value="Anoct_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16178">
        <property type="entry name" value="Anoct_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="511"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="624"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin dimerisation" evidence="10">
        <location>
            <begin position="151"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="9">
        <location>
            <begin position="335"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="253"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3228168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="746" mass="85917" checksum="E948DE6756FA0736" modified="2024-05-29" version="1">MSNISDSNVQLKFHQEPEESANLLNSSRSTILDETMQAINDPNLFNNSSVNIPLTNFSINLNSNYFNPCHSNIIVNSLGDSTFIHFYKKKDASLFEKISNFKKNKQNSSLSDALDKFIDYNKADVFCQLLYKNDTLLPAAVIKFALNKLPENSEKNKKKILDISDFEAELLKLGLICVFELASEAIAEEEVWYIKIFAPFSTLADEAEKVHLKLPTILKKADTIKSRLKEKSVLIKKNKILKRNSSLVEFNENAEIQTSNSKSDTDSDPEIQEDSQKSSALRRRTLRQRMLSLVLNKNPPKAYLPTFVEGPDGTFIGSLKYMFCIITDPQIPHTTFHNSYEMIFDNPLTAPYALFISLWALIFLEFWKRQEATLQVVWGITEMHKLKMYRPQWKGTDIRTSPITGLQEKYHPKRKRLTLKALSFLTLGVGILFIVFIQVLIIVYQALVKGERNGNKDLSKVYIASGLGAAFSLVNIIVFTPIYLRLATTLTDIENHKTEGGWENSFIAKEFVLNFVLTYTPLIFIGVIKVFIKDVWDSANPVYRSYLSELTIQMVIIFMGYQYFYQVVEILMAPLKNLIVKIWEYFSKTEEEKEMKKKKFIYYQDEKLQKYVQRYDFSTKIIQFGFLTLFSAAFPLAPFFALISNIFEIRLDTFKLLTQVQRPFALRQKDIGLCKWFDTKVNTYFDPNYVTGAAMSESTSSKVLAFKFAFWVINVLVPDCPEAIRNYIKHEAYCKKLESGEEADDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9Y7</accession>
    <name>A0AAD5U9Y7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003975</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the REI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9Y7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3226863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="407" mass="47115" checksum="D7674C03403F0C5C" modified="2024-05-29" version="1">MSVDNFNSTSNSNQHLFTCLTCHVAFKDSDIQRDHYKTDWHRYNLKRKVAELDPVNEEQFNLRLASQLNQKTESKISFECQPCKKQFSSQQSLENHFISKKHKESLKKFNPDAIDEEKKPVSASVLAKRENLAENQQWRQQLREAKTEEEVQDLIDIKVQQSVKLEETDCLFCPHQSQNFKANLEHMTVSHSFFIPDLEFLVDLNGLFSHLAEKISVGNICLYCNGKGKGFHTLESVRKHMTDKGHCKIFYQDGAEQEFYDYYVFEESDSEGAEWEDEDDEVNDSSSVVTANTTRIRSKDLAEHIANSANSTELILPSGRKAGHRTYAKYWSQKLKPDITNEAILINQLAGQYKSIGYFNQNQVSMVERRQRKLQGQITNKKALSLQTRLGVKANKFQKHFRPQVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA24</accession>
    <name>A0AAD5UA24_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fanconi anemia group D2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FANCD2</name>
        <name evidence="7" type="ORF">HK099_004070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Fanconi anemia protein FANCD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990918">
        <property type="term" value="P:double-strand break repair involved in meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007129">
        <property type="term" value="P:homologous chromosome pairing at meiosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029448">
        <property type="entry name" value="FANCD2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32086">
        <property type="entry name" value="FANCONI ANEMIA GROUP D2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32086:SF0">
        <property type="entry name" value="FANCONI ANEMIA GROUP D2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14631">
        <property type="entry name" value="FancD2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0832">Ubl conjugation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="612"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="828"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1165"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1177"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1193"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1204"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1244"/>
            <end position="1259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00093456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3226801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1525" mass="173987" checksum="9AB24AB6A70B02FD" modified="2024-05-29" version="1">MNEDYSIEVQNLRNETNKVIIQMNDKLRDEPDVKDLMELLVITILNYHDSNSVHSALENLSFSIQPLHHELLFKILYQNLTSSYIIPFLNVFASLHISNENLDDIHNHVLNILSSAELNQLPIMIRFLLQTIDSSKSRRILIKFRKNLDFENIYRTSSGDQTTLYPETLIIDLLSIIQEVKNQNEFLQFDIITLILITSISPANRRKSLNLLQELLIRNLISVELLLDTLRLHTKGLREYIKDILSIGDEFLRNSYNSGDNLAETFKGINEVIFNDGDTWHKQEIIGNLVTHIGSGIENEIESLISELTIFIRKQLTSHNEKYKRIGVVAALSMIQRLGAVLESRTEIINQSVEMLEMILRYCKQSAVRKREILSLFKNKSDEYLKLLEFQDLSRMRSTQEKSSSSQSWLPNSYLKIEKWMRLNEECSDEVDNSVNIFPLVTNAFSNSTHGIYEIGSTSSSASNNNVITWFNNAHFVSLLPSIFRLYQTLQKHDNDDLEDIDSILGASVVMFKNLDLSTLKATNGKEIKESMCSALFIAINWFRELINAFCYDLKNEDFVRKIMQRLRNIIILEKQLIELAESMHRWIPIGLTEDDLSALKLGGSTAKLVQHPSEKDDIDEEPLNQNHRNAKSNGLLGNNEKKKKFKGKAKISTEIGRFSSVGELRSIFREFEVNLFLLLELDIVDEENESENFEKLEFSTLKYLLEDLHLKIVEKFSLTKKNHKTSNSLSGSGFYSLNRISTSVFIEKVIILIPSMCKIFEKLFNQLSDLSADVTNKKLRKECFELLLKCFEVMLNWNGFKMEARHQLNLKATLQIFSNRYIMKKKRNNGDNNEADDTGDDQKQETRTEDQILNSFHYFSMFIVKKQNDMEETLNLANNLILLRLMDTITTFFDPHFITLKNFTSDDVIEDIEEIRKLYYMKSKLKLCAEAFLKQNWEDKKKSDQLSYLLQKFIGNIPEDEKKLDMIRYHVNTVLKSYAVGNEEVLRKNPFLFKDNFAVYYKILFVELNNVSVNLKVEENNENHLELMEQIVKTFVNLIDLIKIQSVNKLILNVALKKGKSFIDIFLKVLFPILKKNFKHFKDKSTTVLKACQIGTRILQTACNESKVARDTNLLSSVPGLKKSLEMLLYQVKIMLADQGFSSAWFMGNLKHKNLAGEAISSQIPNESEESEDSNDGSQSDDGVNDAYQNRENSDVQSRTEKEIEEDAEEVEHEENLPKKRKISTSAKSKERDIHSPNKAQLGYSSSGRKLSNSQINSSDDDEVNNDKQIVNDSSDSKEDNNISVIKAQLDTISQVITPASQTPVDSTISAPQPILPTSVETSIISIPASVETSFISIPTSSITAPINPPSSACIIGGKPNPSGFMFNFPINTDLSFYFAGTPFFISWSYDTSLPFSAPKNRIVLQYQKASLITTDSKWITINDTLRPNALFYNWTIPETGSGLFKLKIYGDEYSKEGTDVCFPQNFPAPSISPPFKISNVKSIIATTDKFPPNADARELLTLATNDGSTSSVSDLLAAVVSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAD3</accession>
    <name>A0AAD5UAD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD repeat-containing protein 60</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">WDR60</name>
        <name evidence="3" type="ORF">HK099_005155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAD3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042505">
        <property type="entry name" value="DYNC2I1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16022:SF0">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16022">
        <property type="entry name" value="WD REPEAT DOMAIN 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="512"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="889" mass="102784" checksum="6F91E1C6E0F152AB" modified="2024-05-29" version="1">MASRDHKKKDAVDRDAWLANNADILKKKKLDQQQNEKTSQKIESREQQKVKKSATQILDTTQKAKEISQMKNIPSPILETTSKPPNPLNKPKVSKRSNDPDQILEDIPKYDSNDNLNFNDNNNHSPSKKSNTDSAQEKLESNQHEILEEGDYGDDFEDYAEDFEEFVQDDFAEPELHKVIKTSLIQNEKSEMTFNLQKVQEAINVENKKIENDIKLKFEKNQNEKNSFNIKSGGSDSKLNNVSALPQRKILDLSAQQESKKTSLSEEKRLKRWKDLKNLIDLDIVEFQILDLQPLNEYELYIRSFGSSNSVQSATQWDADRLEKDTQCDDWEVEDKWTQAPAEGSKEVDNCFPDLPWLTENGLKEDYEEEERRIKKREALFKNTKIDSLRIVKFLRKSSQVMEFLLEENTVESGISGNFVKEAEISFAKGQIEITLPLFLKGRNVKSVTYSPVDPRIFLTLLSKPVNKNTSGVWDNKGLILMWRLTEPTHPLRILTCECEPMCCTFGTTKPNLIFAGTKDGSIQVWNLNDVEKLSETITIVKTIYIIQKPSYSTDALFFENTCHQGMIKSIVSLDQFEINQKKKKNSLLEGEEKFSQFCTIDEFGFVQFWNCVEIKNYGLEIDLDLGMNIGSSIRVIKDAGFNCVLPRIMNYVQVSTTEIKFRPSDKSKFLIGTDYGLILNQNKFYSEIKNNRNILSIKEYPSYFKQSPQTLKLDSANSINFNNFNKDLFLVGFDSGKISLFNIKYESEIQSWEIPNLTKNKEHTKNNSILKVLWSTQRPSVFFILLKTGLFFIFDLSLNNQTFIKNFNLLQDFKIKYKNCWDFNLSPGKKFETEEQLDDINAKETHLKTNNYHKHASIAFCLDELVLILIFDDEFCEAESLGLKKKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC02</accession>
    <name>A0AAD5UC02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein nedd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NEDD1</name>
        <name evidence="2" type="ORF">HK099_006725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC02"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052818">
        <property type="entry name" value="NEDD1_Spindle_Assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44414">
        <property type="entry name" value="PROTEIN NEDD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44414:SF1">
        <property type="entry name" value="PROTEIN NEDD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="726" mass="81812" checksum="139C4BF54BB2E4AB" modified="2024-05-29" version="1">MALNSKIDILVSNINPRIISTEIFNGHKFTIFSQNSIENFNETTVLSATWNCTGELIAFIDTNHLLHIYNNNTQSLTTPFSLKTTSINKPETITNKIEIPLTFSKRNLNLAVTSISFSHFSNLFGSTGDDGILCLFDPNGKSAPIRSYSKLHNGPIKSLEFSYKIKNQFFTVGSDGIIKIHDIKKRNPLKEINVGAPINCMSLSNEDLILLGTALGDILAYRVDWDNTLAIKKVGNPMDFIAIKPQTVTNFFISNLPLILWVKMKNSTSSTVLAAKKIISEKKETSEEETNDTGFIKTSIPSSVVDGNHLDMFSPVVQKRAISKLLTKSASSSSISNASSKIAPSIRSNFSTKNSISSISTLASAESSNTVYEMSLNQFESGYKNYDTNFKCEDLCENEEVKDRVRNNLSLKFKELQRSGIDESDSTKYSYELNKQSNNKPKITNNDNSDNHKNQDSNNSNDYKIQISDNDITQSTSPQLHLAREGSSNSSVYTSPAVSPNLQSTKGLTQIDPLITKLQNENTLRYPGDRKSLENKSQENSSKDAGLKADDIFQDNMLSKYRNFGGMLGTIPHKENSETNKGLVNISLSNIINQEEIIKSEEDILNQMKKIVKLNVEEELKLNEDFDEKNVDGMGLKNKSIDGHFNDTESKSSFKYKVIESVVEESLKKFKEEIREDFVNLQLEIIRQFHYQKLEIEEVFQKYSFEPLLNEITRLREENDALRRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS16</accession>
    <name>A0AAD5XS16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="3 12">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MPK1_2</name>
        <name evidence="15" type="ORF">HK099_002351</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="3 12"/>
    <dbReference type="EMBL" id="JADGJW010001773">
        <property type="protein sequence ID" value="KAJ3201161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS16"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000647">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="13"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="345"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3201161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="394" mass="44868" checksum="A327F483D6687DAA" modified="2024-05-29" version="1">MDSKFPPILEKKFKMVRELGQGAYGVVCSAKNVETGQDVAIKKVQKVFEKSILAKRALREIKLLRHFNGHENITSILDMEITDVKNFNEIYLVQELMEADLHQIVRSEQPLTDAHFQYFIYQVCRGLKYIHSANVLHRDLKPGNLLVNADCELKICDFGLARGLSDSTTGFMTEYVATRWYRAPEIMLSFKSYTKAIDLWSVDVDQLNQILGVLGTPDDATLRRIGSERAQLYIRSLPKMKKVPWAHLYPKASPAALDLLEKLLTFDPAARIDVEQALAHPYLEAYHDIDDEVKFFNIFFFNDYTNFSQPSCSMTFDFAFEAVESIDEMKSMIAREVMEYKAHTMAQNQASSKPNPVALSGLPTKDLAPVDEDQSQFGGAMDIDEELKLREQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS53</accession>
    <name>A0AAD5XS53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Hexosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_002078</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010001666">
        <property type="protein sequence ID" value="KAJ3201830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS53"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051072">
        <property type="term" value="P:4,6-pyruvylated galactose residue biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF351">
        <property type="entry name" value="BETA-1,3-GALACTOSYLTRANSFERASE PVG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3201830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="321" mass="38148" checksum="97542F6426DE5ED8" modified="2024-05-29" version="1">MFISKKKSKCLTFIPFLFFLSIFVSLSNLDISLLNLTGLQLDDQQLEQELVVNRGDILIDSSSVSGAKNKDKIFIGLLTTAEKFYRRNLIRDTYLNLKPLNIEFKFILGKPKDEETETLLKYENLKHQDLLILDIEENMNNGKTFKYFSTIYELYKEDPFKFVMKTDDDVFLHLPNIEKKFKDMINDGVYYGRSYSTKKGFFMMGMGYVLSWDLVEYIATDPFPRTMVKGQEDSLVSYWLQRGKVIKNKFSDEKGVYWWDFEHRGEERNFIEETILVHSLKKDERFLVINKFFLEYEREKQENSTIRFEDYVKRVKGLITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSG6</accession>
    <name>A0AAD5XSG6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inositol polyphosphate-related phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001329">
        <property type="protein sequence ID" value="KAJ3204188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSG6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF240">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE 5-PHOSPHATASE C9G1.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="538"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="884" mass="99951" checksum="F54F9BF93B90CBE3" modified="2024-05-29" version="1" fragment="single">MRSSNPFLNVTDSDDDSIRTSTTNTAYQHSQMSRLTSQAAPNSSQSLPNLSSNSNPFQIETNPFISYNSLSTNVLHDDLSYLSLTNSYRSTNPFTSFQSLNTSPVLGSPLSPSFSLENSRTTDVLNATTGINGVDISDTSNPLQNLYPNDLGRFNDSNSYTLSNSNPNNPFSSKNDFQTVKNNSKSKINSRSQESVIKDRDKLVICNRRPPLQAKKSFTIPNKIKYIAINMPYIATAFHNIRIWDYNCSSSDYNSSFKMVNEDMKILALIFVPGRNRIWVSLGRGEIWDVDVSGELVEKKLAHAAKITLLLKNDIKRMICSIDENGVLKIWRPNNNGIITLTNEPTRKLISKIPPHIAVVTCDQMLWTCSILDRFLKVYNIKVDEVDLKHKVLNSPVICGFITCLTEYKDNGVLSGHEDGKVVIWDSKLNVTKIITGGGPTKILAILTVRDDIWTGSINGKIQVFSKKNNYQKIKSFIAYNKNPCILLNLNLNSVKNNRLDIISTSDEGQILIWDGLLTNDYIDEQVRLKECVYSTFSTIKALVCTWNVDSMKVSDLQSKDPLFCMDMLTSLTYPDIIVINFQELIALDSAQTQAKNILKKSKPSKMDPSTQWAELFKEELKRHKPHTKYVQLVCKQLVGLYTLVFVSEKNLESIKEVEVDTIKTGFGGIHGNKGSIAVRLLFFDTSICLVNVHLAAHQKEVLSRNNDICTILKDTQFPNLTHNFNVNGGDGSEILDHELVILSGDLNYRIERPREEVIGAALSENFEFLLKYDQLSAQIKHNKHFALRNFKEGKIQFRPTFKYDVNTKNYDTSEKKRVPAYCDRILYFSNENQVLFSKNREGGVNIDGAKFSNQKIKVNRYFSRIESLASDHRPVFAHFTLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XST9</accession>
    <name>A0AAD5XST9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar protease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PEP2_2</name>
        <name evidence="5" type="ORF">HK099_000493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001111">
        <property type="protein sequence ID" value="KAJ3206626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XST9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042050398" evidence="3">
        <location>
            <begin position="19"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="51"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="310"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3206626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="42187" checksum="7D6FAC018B3491CE" modified="2024-05-29" version="1">MKQLHLLNFATLITFAAADFVLPIQLNSNTLNNQISAVPIKNESKSTLLEFFALINIGTPGQPLKLQFETGSYRLWINSMEGMENQFKPQFSSTFNNTNILASMLDVNNAITINGTIAEDKFNLVNSSLNLSDSSIQFIHATTVNLSVSNNFNGLIGLGFTPSDLWNNGTKTFARSFMDQLIEKKVLSNPTVSYFVDFTDVNGEVNFGNMDSTKYSGPITWIPHQSITLSPAAVMPNLPTKVEYLWSVGLRKLNLGKTEINFNTNINVNASAIFATGESVSYFPKELAQNLSLEINSTFNINSNRYEIECSKLSQLPNLTFTFFTDDASVKNEATFELTPYEYALSFDEKQILCFIGIFDNSDTQFQDTILLGNLFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSZ1</accession>
    <name>A0AAD5XSZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000162</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001020">
        <property type="protein sequence ID" value="KAJ3207961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040458">
        <property type="entry name" value="Vid27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013863">
        <property type="entry name" value="VID27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040979">
        <property type="entry name" value="Vid27_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040768">
        <property type="entry name" value="Vid27_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913:SF0">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08553">
        <property type="entry name" value="VID27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17748">
        <property type="entry name" value="VID27_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17747">
        <property type="entry name" value="VID27_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vid27 N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Vid27 PH-like" evidence="3">
        <location>
            <begin position="238"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar import/degradation Vid27 C-terminal" evidence="2">
        <location>
            <begin position="418"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3207961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="754" mass="86624" checksum="6AD7375F705FC5C6" modified="2024-05-29" version="1">MYGMLKSLTNLVISNDTTEKPVASLLSGQFFKIFPYSKLKEELIFKDSSLEIVKATQKNHYLLRVDRIFEEGEEELINEKLSQDDGDDSELNDEVSFLIGRVKINNSLNLMKKKKKELFFHKVDNTLQWIDPLDSSSKIAYKYVPDSEKDIAKFENLLYRCMFETVYKVDQSSISQRDISDFRSVLDDDLKLFIEKKKPVIETPTKPSNPATPVASVTAKEKNNYNFVTKNVLSEKNICQKDVEFFMYSTKSQSFQSVDKGKASIIDNSSFNFSLLLTKNGSPHLLQDITPAMNPIFRTDEIALIWNWIDPVTNSANYSWLIQFESKKDLDEFRLIFAKCLYESLNKGSFDKMNKEDRNCLVDSYLEDEEMDSVESDESDSEAEQSSNQSNFQFNIDYDSDEEQDYARNQLKEDASAKNSQLIVGYKEDRCFVVRGDKIGVFKNTEDNLEFSTTITNVRTMQNQNFSPKNLMLHRKDSQLLMKRPGDDYTIHKMDLEYGKIVEEYKANDMPILDFTPTKKYSQTSLEDTFIGFNNKSIFRLDPRVSGEHKVVTEENKNYITNYNFTAAATTGNGELVVGSETGELRFYNKLGNNAVNRLIGLGEPILGVDSTENGKYLIATCKDFLIFVATEVQDKKNCFTSTLKLENRPKQVRLQLKPEDVQNMKHQGPISFTKARFNQGVGLEEKSIVTSTGPYVVTWNFRRVKQGKLYDYRIKCYTEEVVADNFKFNQDQNIIVALPQNVEMVGKGKLMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTT9</accession>
    <name>A0AAD5XTT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-chaperonin molecular chaperone ATPase</fullName>
            <ecNumber evidence="3">3.6.4.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">KAR2_2</name>
        <name evidence="13" type="ORF">HK099_007265</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.10" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000692">
        <property type="protein sequence ID" value="KAJ3213625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTT9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10241">
        <property type="entry name" value="ASKHA_NBD_HSP70_BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000009">
        <property type="entry name" value="DnaK-type molecular chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000153">
        <property type="entry name" value="Endoplasmic reticulum chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042050">
        <property type="entry name" value="BIP_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042090038" description="non-chaperonin molecular chaperone ATPase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="610"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="537"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="619"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3213625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="660" mass="72364" checksum="9B6A10635C5BF3C4" modified="2024-05-29" version="1">MNKFFKYFTLLCLIALAFADAEEPNKQESTGVIIGIDLGTTYSCVGVYQNSRVDIIANDQGHRITPSYVAFTADGERLVGDAAKNQAPLNPYNTVFDAKRLIGREFSDKDVKADMKHFPFKVVDKGGKPAIEIEIKKGTKKTFSPEEISAMILGKMKEVAENFLGHKVTHAVVTVPAYFNDNQRQATKDAGTIAGLTIARIINEPTAAAIAYGLDKTDGEKNILVYDLGGGTFDVSLLTIDEGVFEVLATSGDTHLGGEDFDNRVIEHFVKLFKKKHSKDVSKDMKALGKLKREVEKAKRALSSQMSVRVEIESFMDGIDLSETLTRAKFEELNMDLFKKTIKPVEKVLKDSGLSKGDINDIVLVGGSTRIPKVVKLLEDFFNGKKASKGINPDEAVAYGAAVQGGILSNTGDDAKLNEMVLLDVNPLTLGIETTGGVMTKLIPRNSQIPTKKSQIFSTAADNQPVVLIQVFEGERPMTKDNNLLGKFELTKIPPAPRGVPQIEVSFEIDVNGILRVSASDKGTGVSESITINNDKGRLSEEDIERMIREAEQFEDEDRILKERIEAKNALENYIYSIKNSVNDDSQLGAKIAEEDKKTILDALKEKSDWLDSNGQTATKEDLEEQKSELENVVNPITSKLYESAGGSGGSAEPEDHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUQ5</accession>
    <name>A0AAD5XUQ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005782</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000467">
        <property type="protein sequence ID" value="KAJ3216634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUQ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="3">
        <location>
            <begin position="202"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="451" mass="50611" checksum="E48EF7F14F6A4D22" modified="2024-05-29" version="1">MDSSDSFGDYGESGNFDSSQDNSYHNDHHSHHGVLGFAGGLLAGGVLGSALSHKNSGNDHIYYQQPPTVVHHLHTNHSNCNSNSISPPELVTNDVFSPLLPSDSQSPLGYTYTRVNEEKNENKCINLLVSIFAMLLFGGLYYYWTNLPNDINRSTIYITGDRKLFESEIYYYDHLQFFGAPNILVSLFDRIPETTDIVEYPPKNLHVNIADGSYVYYRYDLQKGSTISLSWNFEIGIMSPNLMILSSKESFLNWKVKKRRPFFQDVIHEQQSFKGKFEFVTQHYGNYYIIFFPKSRRVKSRGEVGIKVVSKTYSLSEAYFQSYLGDKNSFDIRNGNINSKIYFVVSAPLPVENESGVDNYLVRLNAPVNKGQIMKITIGSLCCCFKKKKGYQSILNNSLNYGNSTYPGLSGNSGLSPQNQPGSVNPSSNQNYGAVNVDGQNVIAPPSYSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV95</accession>
    <name>A0AAD5XV95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000366">
        <property type="protein sequence ID" value="KAJ3218758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV95"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF128">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="32"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="220"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="342" mass="39749" checksum="FD82A2ED8BF47E1B" modified="2024-05-29" version="1">MSNSKPMINEIYNKLGELTVQDLLYSIGEKKKLVSVNEDSTIEYTLNLLKNENLLSLPVYRMSDGEKCLVAMVSIFDILAHSVFAKVFHLKEEEQINVNVDNWVERYLLIVKEERSFFETPVKVVTNSMLTTRESQSNKISDWSIRAEEPLTTLLRMFTTSRFHRALVLPQEKENTFENLKILTQTDFVNFLFKNRLTLLGEEFLKKMEFNENFFKYGLNFTVVPETMKAFDGFKTLYSKGSTGLAVVDAFDKFVGDLSGEDLRYMVKENLDDLLLTIKEFNLKLLCQKKFQVLKKKDLCRNKLHRIWVVDDAHYKPISCISLTTLLTAFVPEHFELLAIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVE0</accession>
    <name>A0AAD5XVE0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001168">
        <property type="protein sequence ID" value="KAJ3205895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVE0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039663">
        <property type="entry name" value="AIP/AIPL1/TTC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242:SF0">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="40"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3205895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="443" mass="51468" checksum="BDDBE1DD40F3B15C" modified="2024-05-29" version="1">MLEELNSDREDYVSTKIKQTKVTEGSKALLNYKAYTFVNQQQKKKNSDSIHKHTKSCNHSTDPTHNHHNHSHEKEKSNNDNQKPLKVIVGDSVDKDPTKPFELRIGLKFSVPSFETCVKTMNVGEKSRFLIMPEKLDGYIGLETALRKEKQNKILAEKGLPIKRQMQSNCCANQFNDVENKDLLDILSSPLELEIHLLDVLEYGTFEKEVWEMKNEERLTEAPKLKEEGNELYNKGNYVEACTKFSRALMLLESITISTEVLDSERERIEELKIAERDKFKPAEEKKIETVPAKSAGFTFDPDFLHFTMQSIRLNYSACKLKLQDYSTVIQQCTEIINKLENFRSSNEFNYFKNKNLYFNYLVKALFRRAKAFSLLGRDLELSKNDLMACKKVLEAKNEFNGSNSSKDFDALVHEIKQEELILEKKFKDYLVKEKKIYSNIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVM0</accession>
    <name>A0AAD5XVM0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001723">
        <property type="protein sequence ID" value="KAJ3201458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVM0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="116" mass="14372" checksum="6ACAA837BE20C35B" modified="2024-05-29" version="1" fragment="single">METREKDRIERQAKIEEIKKIKAEEAERIRQEKFEMTQKQQELEKKIIFEQKLELKRLARQKKKYVDYQLKKAKELKRKATLNSALKVWRPKAILFSDMRLKHENEMYFKVEKIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVT2</accession>
    <name>A0AAD5XVT2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000289">
        <property type="protein sequence ID" value="KAJ3220588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVT2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="27678" checksum="36784300CE54CC63" modified="2024-05-29" version="1">MLKDKTNQMNHHFNNKENITKSLKNYSKNAEIKKTGKLTTSEKKNVKKVNLPNETKDVNESVLESLVKSKNELLSKLNNLPNIKNEEEAILTELRKFKEFLNLIQLESKEEGSFQEGEEKKNAKIVILEKDLFDEKLKNVKLELELETCTENAEILRSSLVDALDENKQLHEIMVDCKENLIKSEKILTSFEKLKNDKDNQMIFEKITKGMEDLDEENLINLTFLSEDEKVKNFTSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW39</accession>
    <name>A0AAD5XW39_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000243">
        <property type="protein sequence ID" value="KAJ3221223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW39"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23821">
        <property type="entry name" value="RWD_IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RWD" evidence="7">
        <location>
            <begin position="3"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="224" mass="25827" checksum="CB1CCDBADC14AF1A" modified="2024-05-29" version="1" fragment="single">MEQELETIAAIYSEEYERITKNEIIITIQLSIGPVSIHFIIPDSYPKTKPFYSIHTCWPVKSAGPGTFKTLQQVDLNYINENFEGLFVENEVVLFEWIEWLRNYLQQNFAEEVENVEEEEEVDNSATNFEELKESNNHVKENGCLKNVIKVFTSLHPIHDKKSEFVGHFAFVNSVQEVQQVRSQLLADKKIAKASHPVISAYRIFPNKSEVLLQDCDDDGETQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW49</accession>
    <name>A0AAD5XW49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000240">
        <property type="protein sequence ID" value="KAJ3221265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW49"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="143" mass="16264" checksum="D32E35271D321793" modified="2024-05-29" version="1">MAHPNDYKPVNNFESSLIINDRYGKHKRLIARIAWKTQNGNFIPMSFVCDTGVPSSFYLSSKAIEILEEYSLLKLDDKGVAYVTVHKDNSGQTFNTTMEETPKVHKNANIVGLKVLLKIGLHISNVHSHSIQILDIYDRSRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW70</accession>
    <name>A0AAD5XW70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001271">
        <property type="protein sequence ID" value="KAJ3204722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW70"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="16456" checksum="C2F6415709600F98" modified="2024-05-29" version="1">MIQIDQYGYASHNNTVSSEARNSKVVRQITRVINNFRENIITGAIINFERSGLIYDFFITLGELVKFLKSSRGKDSDFLKVNHGWKNRWLHFTKDFIDLRDGLTHNVYQVRFVEDGATLPRREGATSKKVGEVVKICWNTLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWA6</accession>
    <name>A0AAD5XWA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Retinal guanylyl cyclase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GUCY2F</name>
        <name evidence="13" type="ORF">HK099_003286</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002179">
        <property type="protein sequence ID" value="KAJ3199143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWA6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000050">
        <property type="entry name" value="Guanylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="12">
        <location>
            <begin position="46"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3199143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="241" mass="26521" checksum="26B2CCA31C4351CF" modified="2024-05-29" version="1">MKALIDNLAVARKKSKNLLGQMLPSEVADRIMAGEITKPVSFECATVFFSNIVGFSDIAAEANSIDIVNLLNDLYKYFDTIIDNHDVYKVETVGSQYMVVSGIPKRNGENHVSEIADMALTLMSGIYSTFKVRNLDIKVELRIGIHSGPTVAGVVGTKAPRYCLFGDTVNTAARMESSGSAMRIQVSEPTYELLRKTGQYNFEIRGKIPVKGKGHMTTYWLTGKTGFISPLPKLEDFPLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWP5</accession>
    <name>A0AAD5XWP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000189">
        <property type="protein sequence ID" value="KAJ3222150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWP5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="888"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1112"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1123"/>
            <end position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1155" mass="130031" checksum="F93505355E8C225A" modified="2024-05-29" version="1">MLDGSLVANTHQIIEITKTVNKNELKDHVSSDNQMIKSQSVEVDNTKRIFSVNRPLLEGGDYTFSNLEKGKSSYFIHFPTQLFSWKATVFESNGGKVKLKYKIKHNSSSGKQEETNLKNPTHKQLCCKLTKNLVDENEDIFSRTFSIILNNEIKVFEWLKTAPKQLKLFDLSAQCLVAKCNSEYNNKNSSTGFKKKGHLTIYPSGYEIEDLIVSTCFITLERRGFNEKSSNSNRNSISAFPAIKTTSLDSKKRVSHDLTLKVENKFPHYDSEKKKSLSDLENNIKRQLDQLHKENSEPALNENTRNNDITISNELPQTPTNKRSSIYVDNFNKILQKENKSRLPLEKTPYQLHNKTIIGNKETKNDSVEKKQHLPAFTNNSILKDLKYEDSLIKEMSEIWKNISFDNSFDNNHSINTESTSTRIISTNSSIPEKLSSVETCNNDSRFSILNSRQTHLVNEIKNNSILQKNLYEEPFHSESLSRNTSTEHFSENSSNLVQQRELSKGVPTSSMYGGAASSKAFSQSQTPIPTKPVFQANRTAKADNKVFHSVPAPEHPDIVVADKSFKSVPLLVVQDVTSESIKSQQPSHHHPIASVSMYEEKKLLQIRQDTIGLRQNNECHNKESYQEASSSQVDSLLPPTLVTQSYDQMETSKYANPMFSNSNRTVSTLPKYFPSLSSPPIPDNPEIVNHDIPFIDNFSKRVAKRSNRLSLPVALPNSGEAIAPGRPVGPWGYGMLSPVPTRTPSPLIDSPVINNTPILNSLGVNQSLPSSPIHLAENNSNRSPVINRHESNLKQELLQHSSASSLEVNNSLKNFSSSLKSIPKKIFSHFILEPENYGVICEKPLITHSKKSVSYVYKAEKLFLQQVDAKSLVSQISSTSLPISQMRSRQENSNIIDSNTGVDKNSFDVNNQSGSQPTSNNNLLNSFHYDYPVTNDRENNFVANMNTNTNIAAVLNSTQNDNFASNEKNNPLNSFLYGSPHTSYYESPSYQEGYRNSCNMEKSTNECNDEKTGFVHDSVPNLNRTFQTEGNSVEMGQDGINSNSSFHKNGQLQQESTTYGSISGHQQSHIVDGYQTFQPKKPLVKNNFMQYRNNWANYEFSQSSLPSSTSPINVTSTSPTQKNDNIKNNNKNLEDNIDLEKILIEGLKRDNESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWQ7</accession>
    <name>A0AAD5XWQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thioredoxin-like 4A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TXNL4A</name>
        <name evidence="7" type="ORF">HK099_002045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DIM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001647">
        <property type="protein sequence ID" value="KAJ3201944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWQ7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004123">
        <property type="entry name" value="Dim1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052:SF5">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEN 4A, 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02966">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01410">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S26" evidence="6">
        <location>
            <begin position="121"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S26" evidence="6">
        <location>
            <begin position="174"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3201944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="244" mass="27899" checksum="99A7537E559CD1E1" modified="2024-05-29" version="1">MYELYDPCTVMFFYRNKHIMIDLGTGNNNKINWALEDKGEMIDIVETVFRGARKGVVGEVDVNACTKEEIENLTTGEKGTATELVDVLAELQLDWESIKVSFEVEQVKLTFFKEGLVYTISNDYVIINKLSKFKRGDVVTCISPINPFRTIVKRLIAVAGDEIFIDPTNNLSEKIIIPKGHVWLQGDNYESSRDSRFFGPVSINLLQGKVVYKFSFPFFFNLIKIKNSFEDNVDPSKVVSYNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWS2</accession>
    <name>A0AAD5XWS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000981">
        <property type="protein sequence ID" value="KAJ3208688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWS2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045820">
        <property type="term" value="P:negative regulation of glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043456">
        <property type="term" value="P:regulation of pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051695">
        <property type="entry name" value="Phosphoglycerate_Mutase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46517:SF1">
        <property type="entry name" value="FRUCTOSE-2,6-BISPHOSPHATASE TIGAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="373" mass="42701" checksum="ABBBC9D0664AD3F5" modified="2024-05-29" version="1" fragment="single">AETDVNSQVPRVLQGQSDTDLNEAGLKQAIALAKYLKKETFDHFYCSDLKRSQQTLKEIQKFHPSVPVHLRQELREQDLGNLTGLSWPLAKKILKKADKSMEEYMETNGTGESNQNFFERTQNFYTEIVKKHLVEPHSEILKKNMQIFENNLKLIDNEKVDKTPNDSELKSIPIERRTSREILSSKCSLNSLLPGSIPSDDDLTAVGSKNNSCHLNIPQQQPQQKLDSLKNLKKVLLEKQIKMKETKILLMTHGGFIQNLLKFLKDELHFELKCEYSHGFPKCTGIYKFLITKIEKPNFDYDWLGKIVLINGLSHLAVQIKKEYSKENLTDSNSSKSSLDKSTIPEFVKSNSFNAAIHRVGSDPNINRKNLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWU0</accession>
    <name>A0AAD5XWU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_006698</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000599">
        <property type="protein sequence ID" value="KAJ3214683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWU0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015218">
        <property type="term" value="F:pyrimidine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990519">
        <property type="term" value="P:pyrimidine nucleotide import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF1">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06780)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="2"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="96"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="204"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3214683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="34725" checksum="BC3832CA0501CC04" modified="2024-05-29" version="1">MDYAFAGAMSGLVAGIIVCPLDVVKVRLQNQPPISLTNYNGTFPTLVRIAKEEGLKGLFSGLSPTILSYLCDRMLWFATYESFKVAISNHTTRKLDDPFVHSGSALLSSVVCVVGITPLWVIRTRMMTQNTETIYYYRSVSHAFKSIIKKEGLTSLYRGLIPSFLGIAHPLIQFPLYERFKIVISNYEHHSKLEDYNPNKRPELSNLGILTSSIVSKFIAAVITYPHEVIRTRLQTQTAPLNKNFSNNTSVIPNIVPYNGIVKTVKNMVVEEGWKSLYKGLPTNLIRTIPSAGISLWTYEMILNNMKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXA9</accession>
    <name>A0AAD5XXA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SPT3 Dosage dependent suppressor of Ty-induced promoter mutations-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SPT23</name>
        <name evidence="5" type="ORF">HK099_001209</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000132">
        <property type="protein sequence ID" value="KAJ3223383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057962">
        <property type="entry name" value="SPT23_MGA2_DBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23335">
        <property type="entry name" value="CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23335:SF1">
        <property type="entry name" value="CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25603">
        <property type="entry name" value="SPT23_MGA2_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="941"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="4">
        <location>
            <begin position="481"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1000" mass="112974" checksum="5B7F2421F8F68B97" modified="2024-05-29" version="1">MPDCPDISSNNKYQKLQSSKSSINSANSSPTFDFEMLKSSSVNSSDDDSAYSSLKGEEQLSEKKKPIPSPPLSTSYITDNDITLDTNELIKTVKAKMDTKVHFQSDDLQIRVLGVPLINAKSRVETQIKLCIQLLTKKGEKSQLKCSHLKLPEHLVSKEKVKKQRQNEVECVSSLLELEAIVVCVSDVDKSVKTCLGCVQRERKRSKKRESTKIKKGSDEDCDRMDDDTELEAEQSRIIIFNCAQYLDFSNGDTFLPTRITCYCRHHAEKIGFCIYFILRDHSKNIIATGLSPPILITDDHKSNKPKIMKKPSSLSAKKSNNINKNNSCNSLNEASLPNNFKINNQNILGLKLMEEILNNNQQQTDLSGSSSSNVFENCNPYLSPPNYRFDNSQLLHNQQNVFSTSNDGNLKNRKRQRNSITGGNGDFSNDNQQLMLEDFLDFPLSPASENNSVFNAANFSTPANLIFQQQPNMVVRIPKPPNISKVIPAEGPIHGGLEITILGSDFFDGLTVLFGDIPALTTFWSQNTLVCVLPPSSVPGAVKVSFKELSIIENENLTFTYKDETERALLELALQVVGLRMTGKIDDPRQIAMKIVNDTSNSTTTQRISNENYQQEASMVEEFKTTLNLQNMQRNELEESILESLRATSSIYELNYSQQSTGLNLLMLSIILGYDKLAAFLIAKKANLEHRDLNGNNCLIYSVMFQRHLISDVLLKAGVNKITKNFFGKDAADVALDYKNLKFLELLEDPKVDTPSIEKFDMEIKEDIKEQKNAKNLIEVTKKVAGIPQHWFPQIPHFPDVTFPQMPNVTFPQMPNVTFPQMPNVTFPQMPNPYVWWNGFQFQLRHGYAQPQQIQSTAQSNIPPNMNNTASHDIPKEHKMPSRLHRIFNKIRPSSSWSRVCDCGICGRCRENIAKRRLANRSQTQSVDNKLDSQETFTFTLFKFIFVLILLALLHYTVTVYEDVIFGFVETFINVGELRNYFATARPGQLLPGVPVRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXD6</accession>
    <name>A0AAD5XXD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000465">
        <property type="protein sequence ID" value="KAJ3216676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXD6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042244822" evidence="1">
        <location>
            <begin position="23"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="189" mass="19970" checksum="FB2436D726F50433" modified="2024-05-29" version="1">MVSTNQFMMLCLLITSAALVKAANIISDSIKLSARDSCSWPGHCEGSKCATHDDCADSFECRNLICSKVQVIGEGSSCTSDDQCDGDLECRNLVCSKPIVGSCSWPGHCLGDVCASMDECADDLTCINGLCGKEAEVPTPDVTTVVATTTTATVVTGTIKPGFKCNLELQDCCCNKKCIKGVRFAVCEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXE4</accession>
    <name>A0AAD5XXE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000461">
        <property type="protein sequence ID" value="KAJ3216765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXE4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01511">
        <property type="entry name" value="ATPase-IB1_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01512">
        <property type="entry name" value="ATPase-IB2_Cd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594:SF4">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00943">
        <property type="entry name" value="CUATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="490"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="642"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="675"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="970"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1001"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="236"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3216765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1025" mass="113192" checksum="FFDFF66233C40F7A" modified="2024-05-29" version="1">MENKPCCNSNKPKKPQMEAISLTTREPKELTCCKTRKNEVHNKAIVSIISVNKSNSCSAADINKIEILSEIINKNEPISRCDSKKKPLAVTTSCCSEKKSSCSQKNEICVSKTNCSNIKKKSSCCNTEIDNSLSEAAENIKNGCSSKIKCENPAETEVSRCTEKNEITPCTDKMEKPIKDTSLYNKTKKNSCCEDDCENSVTSISTCKETQNVSCCKDESCLKTPPETAIAIYNGTKLEFDVQGLTCTSCEKFLFKTLNTLPGITDVKTSLILNKAEFIYDPTILEPTQIMQYVIEKTGFLCKISYSKNSNQYRVLFNKKLSKDIQLLPGITNFELTDNLAIIDYDPSLIGIRDILHHYQEWLPELVKEEPVDIEKATLLELKSWFYRMWLSIFLCIPVLIFTYVELPEKTIVGDLELWTLLSFILATIIQFYVGLPIYQAAFKSLINQKSIEMDMLVVLSTTTAYLYSTAAMIITAVKLSIGTHFFETSSLLITIIIIGRYITIYVRGKTASVLKEVCSLQPHTAILVTSELKETEIDVSLLHIGDILKILPDQRIVTDGIIVEGESEVDESMITGEHIPVFKSTGHRAIAGTLNLTGTLWVKVTHLSTENTLSNIQLLIKEAQSSRAYSQEIADKIASKFTPVVVLLSIIVFLIWFIIGLVSAKNFSTSFVTALLYGITILIVSCPCAIGLAVPTVIIVASGVAARNGIIFKDAKSFETAYKCNLVVFDKTGTLTLGKFQVADEYILKNDNTKELILSVVQSSNHPLSIAIKDFLGTENLVPSATTVKSIPGKGLEAAIDGDIIKIGNAKWLNCENHEILKNVQNKSLVCISKNEELIAVYTLVDELKPEAKEIIENLNNLKIETYILSGDNQQSIDSLNLNVKSALGNCTPEDKLKYIKRKQQEGNIVFFCGDGTNDAPAIVQADIGVSMSTGTDIATSSSNIVLLNGDLRSILKIIKLSSETVKRIYINFGWSLIYNVFAIALAAGAFIVVRIPPELAALGELVSVLPVLLVAILFRTFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXJ8</accession>
    <name>A0AAD5XXJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Argonaute 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">AGO1_3</name>
        <name evidence="5" type="ORF">HK099_005513</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family. Ago subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000431">
        <property type="protein sequence ID" value="KAJ3217348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXJ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.260.10:FF:000001">
        <property type="entry name" value="Protein argonaute-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0943">RNA-mediated gene silencing</keyword>
    <feature type="domain" description="PAZ" evidence="3">
        <location>
            <begin position="198"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="4">
        <location>
            <begin position="491"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="868" mass="97457" checksum="F5683EC5F9E3653C" modified="2024-05-29" version="1" fragment="single">MQINSISGLMTNLTLRPPLGNSGRQIQVRANFFPITSLPQSNIHHYDIQIIPDVPPAKNRRIYQLWLENNKIKLEAVPIFDGRHNMFSIRDLPLQDDPYSLDYFDTEDPLAKRKNPKTFVMTIKKIGEIKMNNLGLFLDGRISEAPLDAMMALVCDSSQSIANGAQLWQGFHQSIRPSRGQMLINLDVSATAFYQPGPILEIMAKILGKNSPNDLRQGITDKDRIKLEKALKGIKVVVTHRGQIRRKYRISKITNTPAHRTMFPLGEAANMQEESVSNYFKNKYNLNLYFPQLPCLVVGDVSKNIYLPLEVCDIVKGQRHLRKLNERQTAEMIKFTCQPPHVRSNKISAGITILQQRDNEYLKEFNVQIGHEMAIVNARVLPAPTISYHPASKEPLITPREGAWNLRDKMVAQGITMRSWSVVAFGSEQDYPVGAIQKFITLLVQTCEECGVFIQNRQPPISYAQPHGNIEKTLIDAYMVAGNSFNERPQLIVCILPNTGVPLYAEIKRVSDTVIGIATQCIQAKHMFAAKRQYCANVCLKMNVKLGGMNSYLSNTQLPFVSSSPTIVFGADVTHPAPGSASNQSIAALVGSMDAQCSRYAASIRVQTGRQEVISDLNSMIIELLKTFYQTCGAKPERIVFYRDGVSEQQFNDVLAFEVDAIRRACQNLEQNYRPTITFIVVQKRHHARFFPIRKEDSDRSGNVLPGTVIEAGVTHPSAFNVEFDFYLCSHPGLQGTSKPTHYHVLRDENNFSSDSLQELTYRMCYLYCRATRSVSVCPPAYYAHLVAARARFHATDKEIDELQQQINNSGGLIQGSVGGMIGVPPQDILFQSPNPVTQMRGRGFTKRASTIFDRGLVYGVVKPELTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="2" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXT1</accession>
    <name>A0AAD5XXT1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1325" mass="150371" checksum="7D3CAA9112A59A93" modified="2024-05-29" version="1">MSLHQIKNVVFNPLLQTRLEIETFLKSQNPETAHPFSNDILLFFDGTSVKEINISDKPSTFFIDNAKLNDLGDVLLERLQLHKNTLQEIVDYTLILPNDSIIEIPWKQDSIVLFALSIRQPTYYDLCIGNENGDVITYNSKKSRSISGLLHSGDIIRNDTLLQTVRTDSNVPTQCEAVVFVSGYNYTQLNIYEKFRPSVLVANHELKLLYLITIPLDLSSVGKATLCCPLVYESNIDGTIKIKILPTPPKAEQIFASGSSLPGATLSFQRSITISKSLQQEFTGMSTQESLHTFESVKKEEDIVSELLKDVEEGLTLIVENGCDASEIAAAYNPTTVLRYGLGLSVAKEYTFVNEEEFIFPLCLGNVLQGGNVLALGKPWVGSKVNVSKLIDEQSLGIIFVVSDKMSDQAVKLNPHLRCNNSLFILIPSNTKKLKFSTHKSLVEFMNNLNINSIQSLAGPCSFVVVKINSKYFFYRGTRIEGLTSSIPNFGDDVTDIVLQYGDHCKKNLALSEKNKEKQFSSLISLKEEKIIFNGHTFSVDDLFKFFDMISFEELNIRKDEVCDTFSQLSVLFSYERLTEITGKLLIKIKTRIDKEVAAFKKNYVDFVENNFLVERNDQEERLYRNEKNRLYSVFRGSERNLKIESQFFVDLIGNTISSRGSSSRMHNLNQLIRKRKIAANVSSSKEVTYDDLCDLLDEHCSAVGCVIGNLDQGNLPSCLQRVAAGENFQLNNFVTFDRRNLVLEGLDVGIVMNHHSGSNNQNMLTATDDSISFSLCIGNQLAIPWPLFDEFVELKNPYEVPWINICNEPHIAKLRILIRGTFSQSQLSREFAIPPASKYLGKFLLSLLLDLMCDLANSGRNNVSKFDDKKSQIMRGLFGQLFTLMASGGREIKNESKLNYLFIKIGAPLCPAHYLLSMNSSFSDILPEDEWWIYEKIVYCFPYTCWDDKILKRNIAVLLVRSIRRCITDPVTLSMRKSIDQLKKNNLQTITVQVDKQLEFLQVAVEVIRRLNVSDEKHQKDNRLVAQRLLTRKPNYPKLNRGFGIVVRYLECIAEHGLTSQKQHLRVLQACFDMFCKRSGHFKDGKRKIIKGENKPEAAMDLISEAEKIQKAWFEMDLRSLQNYQTVEKIAADSEDYPVSNLIKSLKGDAELNRVSWKISKDGLPPKIDANFFTFVMTGNEKDETATTVTTTTESLSVVDLREVNYEQEVINKLTKVPNSSKAVDLIQRLKLLTFTKILELSKNDINSRIFLKLIGYLNKELQISEIDDVAFDFSILELNNEKNLREQAVLEKCEAVLKKIVLILLENWRDALEGEHIAAVCLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXV3</accession>
    <name>A0AAD5XXV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000086">
        <property type="protein sequence ID" value="KAJ3224638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXV3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="101" mass="11875" checksum="4F288D4F2FE7E2B0" modified="2024-05-29" version="1">MSKYSKIADVEENLDNEHDQLEFQNFVLNSAEQNLTSGNFKAQSQPTQNRDNQNFGFSTGQPNNNNQDQNKQQHAFYTLEYYMTFFDVDTNDVNYLEKNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY58</accession>
    <name>A0AAD5XY58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DEAH-box ATP-dependent RNA helicase prp22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRP22_4</name>
        <name evidence="6" type="ORF">HK099_006559</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000575">
        <property type="protein sequence ID" value="KAJ3215024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY58"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="16"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="216"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="754"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3215024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="797" mass="91943" checksum="F443603B3B1F9870" modified="2024-05-29" version="1">MSQEQLPIFDFKNELISAIKEYPFLIVVGDTGSGKTTQLPQYCLEAFPESKIVVTQPRRIAAISAAKRVSEERNVTLGEEIGYGVRFEKCYTQKSMLTYMTDGLLLRELINDNELNSFDIYVLDEAHERSLDTDILFGLLKNSVKKKLSDDTESEKSKKLRIIVMSATLDAEKFSNFFDHCPIFSIPGRMFEVDILWQKNINMNTLKNSFLHRCVKTAFNIHTTENEGDILVFLTGKNEIEQACRQIMDLEREYDYSKIHNGYNGIMCYPIYSSLETFEQKNIFKLPPRGIRKIVFSTNIAQTSVTVPGIRFVVDSGFVKQKVYDPKNSMDTLLTVPISQSAATQRAGRAGKPLASRTETGKVFRLYGTEAFDKMDLDTSPEIQRCSLIGTVLSLLKMEIHNVLEFEFIDKPDEELIKSALKSLWVLGAVNDEGKLTEIGKMMAELPVSPFLARSLIASVTENCSFEMITIAAILSVEDIFLSPRTEEKKIQAEEIWNEEFAYPKSDHLTFLKIFLMWEEFSSSSRIRDDGKNWCKDHFLHCRSLRTAKNVRDQLFQIFERTLHLKITKCPIKIPKKRKTDSGEKRMRELDINEISASNLLNHLETDAILKSLCAGFWFNTAKKQKTKNYFHFYLNSRFDTKIKNILLKKDVLKNFQQALYIPKQSFTLKKILDDQQKLSQETFLIFQDLNFNMKPVMKNISLVDFKFIEKYFFELEKKLHSKTDFNNISFLNFDEALTNKSEATEVEPSSIALEDSGMVNSVEENSIENENSEDASTQRSERVRLARERYLNRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY94</accession>
    <name>A0AAD5XY94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA repair protein RAD51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RAD51</name>
        <name evidence="12" type="ORF">HK099_004384</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required both for recombination and for the repair of DNA damage caused by X-rays.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RecA family. RAD51 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000306">
        <property type="protein sequence ID" value="KAJ3220330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY94"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990426">
        <property type="term" value="P:mitotic recombination-dependent replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19513">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000008">
        <property type="entry name" value="DNA repair protein RAD51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002052">
        <property type="entry name" value="DNA repair protein RAD51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011941">
        <property type="entry name" value="DNA_recomb/repair_Rad51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02239">
        <property type="entry name" value="recomb_RAD51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF39">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14520">
        <property type="entry name" value="HHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="10">
        <location>
            <begin position="97"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="11">
        <location>
            <begin position="262"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3220330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="325" mass="35608" checksum="10E920C4D8021816" modified="2024-05-29" version="1">MSTVAVQQQIEEEEEEEQNGPIPVQKLEQFGISAADCKKLADAGYHTVESIAFTPVRQLITIKGISDQKAEKIISEASKLVPMGFTTATEFQQRRQELILISTGSKELDKLLGGGIETGSITELFGEFRTGKSQICHTLAVICQLPTDMGGAEGKCIYIDTEGTFRPERLCDVARRFGVDENQVLDNVVCARAYNTDHQNKLLMTACAMMTESRFSLLIVDSATSLYRTDFSGRGELSARQMHLARFLRTLLRLADEVDGGAAMFTADPKKPIGGNIIAHASTTRLYLKKGRGDTRICKIYDSPCLPEAEALFAINADGIGDAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYA8</accession>
    <name>A0AAD5XYA8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004267</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000299">
        <property type="protein sequence ID" value="KAJ3220476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYA8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDIA6-like C-terminal thioredoxin-like" evidence="7">
        <location>
            <begin position="141"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="287" mass="32947" checksum="251905DC37F1E0F9" modified="2024-05-29" version="1">MVEFAVSKIPSNYIKIIDGQKVTDESFLSENPDLSKVMLFSKNEKTPPLFKALGIEYDQRLLLGEVKPSNKALAKKFNVTKFPSVIVSKHHEEEVNSIERYDGILKYKNLVEFFNTFAKEKKKEKKTDQKVKEEKKKGKETVLEFDPVIPQAKSLEDLKKFCYEQKKTCLISVLAPNEEDTLEETLSVLVETKKKFEKNFFSVYINILETPLFIPLLKNVFDVSDMYPSAVAVNFQRGWYRNFRGGFDAIGLASFLQDISKGKGKNSKIPDLTSFFNPVRSIVKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYH2</accession>
    <name>A0AAD5XYH2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Cu(+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ACA10_5</name>
        <name evidence="18" type="ORF">HK099_006091</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.8" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000503">
        <property type="protein sequence ID" value="KAJ3216021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYH2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140581">
        <property type="term" value="F:P-type monovalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000029">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000144">
        <property type="entry name" value="copper-transporting ATPase 1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-0187">Copper transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="17">
        <location>
            <begin position="77"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="16">
        <location>
            <begin position="177"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3216021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="754" mass="82082" checksum="65F45AFB66EB08A0" modified="2024-05-29" version="1" fragment="single">MSFTLEPNQLVDFVEPKSPQKLVEYGGVEKVAVALKTDLNNGLSSTSNDAVIIHTDTQPHLENNDKKSIPTATNNVFNERIHFYGTNTLPPPKSKSFFQFSWEAAGDRTLQILVVAAITEIAVGIYKIVKSKETAGIWDGLAIVFAVIIIILITAGNDYRKQSQFRQLNEFSRGLAQTKVIRNGHTVQIKNSDLLVGDIALIDTGDILPADGIYISGSHLKCDESSLTGESNVVAKDEVKDPFLLSGTKVVNGVGKMLIIGTGVNSINGRIMMTLTNEAEATPLQKKLDFIANQIGKFGLAAAILMVVVLVVSYFAINPRFDQIKIADDMINIIMSAITLVVVAIPEGLPLAVTMALAHATLRMLKDNNLVRHLSSCETMGNATTICSDKTGTLTLNQMAVVKGCIFNTDFTKNDRTASFDSKIFSTRSKQHKDNLLAFLSNSLNVNSSADETENEEGKINFNGSKTEIALLDFTKSLGYEYKKDRKNTEIIDLIPFSSDNKKMTTTVKLAGNKIFEAFQKDFSEFGELFIYSKGAAEIVLSTCDKFVNDQGIIQEMAPEKLKIFQLLIESYASQALRTIAFGFKPFNSSNKSNLEIPVNDMITLSTTDPLVYSGDGFKEDPSKSGMILLGIVGIEDPVRPEVPDAVKSCQRAGVVVRMVTGDNKATARSIAKQCGILTDGGVVMEGPDFRKLSREEMDAIVPKLQVLARSSPLDKQILVNTLKSMYHNINGIGETVAVTGDGTNDAPALKSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ89</accession>
    <name>A0AAD5XZ89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004994</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000371">
        <property type="protein sequence ID" value="KAJ3218623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035348">
        <property type="term" value="P:acetyl-CoA transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2461"/>
            <end position="2486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2525"/>
            <end position="2542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2562"/>
            <end position="2584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2604"/>
            <end position="2623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2657"/>
            <end position="2677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2689"/>
            <end position="2708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2720"/>
            <end position="2739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2751"/>
            <end position="2772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2841"/>
            <end position="2861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="596"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2973"/>
            <end position="2995"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="75"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="408"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="651"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="871"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1020"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1073"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1505"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1570"/>
            <end position="1683"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1747"/>
            <end position="1844"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1983"/>
            <end position="2128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2165"/>
            <end position="2271"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2338"/>
            <end position="2401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="612"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2977"/>
            <end position="2995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3218623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2995" mass="344361" checksum="5CEF32A142AD641C" modified="2024-05-29" version="1">MLSEKNLSPDWNFLLQKEVQNVIENKSEIESQIESIYPTLVSIKIDLSDKNATKENILGLFKLAQLGMELKNIYLEQAESQIRTVEATLEAQEDELKKLRILSMGPQSALVSAEMKSLEETIQDLELRNESLTQDLSEKEETLENEKKKTSTLTDHLKEESAKVTKLEETLGKLKRELSDARLKVFAKKDTVNETLDDIHFKNTIKEKNAQISNYITEVQNLSTRNAYLASENEAMTQEIEAAVFELDKYANEKVSNQKILLKNDQLIDHLTEEKNSLKYQLNELAEQIQSRGGKDEGLLEELQSEVIRHKKSARESYSGLLEKTSENEILHEKVKLLKEELDSLGIDTIKKDLSERDEIISVLKEKLEGAYQDIELLSTDWDNLETLLNSQKNEANMETIKTNFAQVQKLKEKMQAYKLRRKEDLKKASTFNEQLEEKEKELIDLRLQIEKYENGVYGLPDAIREIKNLKLKMNLRNNEISELTLKINDFELQANEFIEENSELRNKLGISKKTKIDLTNLKSNTILELEKAKALNVCLQKEVDDLEEERLKLKSELRFQSREKGENAIAMGLTVDDLIAVEDYANKLRMGADTSNDSLDEKTRGLKIKKKNGDGTEEKSRGLGNISRPNLSNNQLDKFLLELERTHVEGEEYREAISTLQTDLEKYKDENRALESVIREISLTLIKTRSTAPEQKGQPQSEVAFPIVQKLMKILENKEKRIRAMDMGKDASEDILEMNIQLREELSDVRALLDQSSHSLYLKNCEFEKLQADFSKLKEKSDLPRKRLLNLPADLVLGTVHDYSALVEQLIECLSDSQTKDKEILETKKSLEQYHEKYSILMGRQKLLYKDYHEQETKHIEQTKTMQDMTNEAEHQKEIAQMKAKELEHMVENLKAGPEEISRNYIVVHRNFIALKANEAVLIRRHKALTEVESHLRKHNSSLQADVLALDKSAKETIMRLIVKKKELEVKVEVLLRKLDESVPATLLAQADHKLEAYIAKTRLLLEREQEWICQKSHCEIEIKKARETNEENEKLQLQYFKAQETAVKMEDALGALSNQFSSGGPISRNQVVEAYQKIAKLEVELQVLKKRSELAEFKCEMLGKVEIETKDRLATVDRLYIESMEENMRLRDTEMNLKNSYEGGADKEQNEKNLKEIEQLKTNLDTLQHETLKCKYSLKRKEKLTYSKQIDKHLSEISTQQASDLIRLHAIDEKEKEILNAAIIELQMDGEERLLIGKMHQHIIALQVSESQALRKMEILAAKCLQLETNVVQLEKVIDIKDNHIYQMHLDSKSRVRILQGVVSDLRARMSGVVLLSKHERTCNLVQQLNSSKIEMDVEMRKTMAEKRNIEDKLVVALEKVQTQEQLISTLRDNTPGQAMILNWHKKMSENQLSELKLQREVMHMKQSETMAVKELEDSNKRTAQLELELVELQSFYDGDKINWEQREFELELKIQGYEEEREKIFQAATVRELKEALPDRTLPIYQQLEVALRLLVERTRLLATQDIKIAELENKLKINKEELDDLESEKFKKDYELNDIKQNMTQYSVDSNKFKEIKEEEFRNKIREREEHAMKTAQTMIASLRRQLAQKNDMVDKYQNMMLEMRDRMGKINEEEEVKKFREQVLQLEEKLEFEKKTSLQKIESLNNDLITKLSEIEHQEEQIAELEEQVKDLKAMTDESVYKEMEDMIVNLKKQIFKRDKEHIKHTKAISELKKCLLQFSVKEESLNMKLNEEAEALDDDMIKKYEAKIDKLKIGVDRYRNDVSSLEHKNRQLIEENQGLMESLSKKKKDVNQILVDLNRLQKNLREKDKKVIELGLKMTKINEENENLHKKYSVLENKYKVSEKSFSQSKVQIQSKTLQSSKATSLSQKTIESIKKPIMKSVMIQTIANLNEKNSSNNEVQGFKTKIKTLEDSLTIKTVEVEKCNQEIKLLKYNSSKEKEIAQNANNIEVLGKNKNDDFSELCFLKSSGEELTVEKFNEQKNRLKALELEVENWRKIAEFDKPNEIRKIQKKCKQLHEKNQELEELNKNLHKNHYFDELNKGASRGERSMQLSMVLESRIKDLMEKNHSLENSFDDLKNEISSARFEVDAAVASEKRKDIEIKEIIKEMEELKIATKKKLEEGPAVLMPGLTISTPWSELDKALTPRAKNSTEDLIKVIEHLSKTNDSLKSDIEYLKKQNPSNVKYMDLLKEYKKQKLIIEENKKCSEEKNETSLQLAKIEQENGKLRKQVKKFSDGQLKLIKEEKKIEIENDTLKKEITTLRATLSELGYSLGDEEIELNTRMNTTANSLNHSTCCKEINELKADVQEKDDIIRKLMNPENSNTEKLIAEVRKLTKEVDLWKLRVNNLNNKIKDQESKIINNDDNTEFLIKKSLREIQNKNALLSEELEDLKYNYRVALKSNIELEDKLKGVQTRTGSSKNLKDEIEYKPLQYVGEDIKVNELESNLRTDLPDFILLCVLYLLQGVPLGLALGSIPFILKSKLSFSDLALFSLSSYPYSLKLLVNSIYFKSFGRRKSWIVPIQAVTGLTLFLMGGKIENLLESETIPVKSLVLAFTSLVFLCATQDIAVDGWALTLLSDKNKAYASTAQTIGLTTGYFLSFTVFLALNSAEFWLVLFKTEKREVDGGPEEILEVYNTIWKVCKTPHMKQFIVILMIAKIGFIANENVTGLKLLEYGFKKEDLALAVLLDFPCQLLFGYYAARWSAGPKPLRPWLYAFHGRLILALLGMLVVYSFPSDGIVTTNYFLVVIVSTVLSSFMSTVQFVGMGSFFTKISDPVIGGTYMTLLNTLKAVDLFTISRCSKQGENGLFNTCSSESSKISCKSLGGDCETEQDGYYYVALGCFLLGFLSLTFIIRPTIGYIENLNERACSLPARDRGDSGNHGHSCHWYEHHGKDDSHCNGDSNSNSETTVDPVAITVDPVATTVDPNLTTSDPVATTVDAVATTSDPVATTIDLSDLAGVFATAEPDKNTPTATNNQNTATATNTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZH3</accession>
    <name>A0AAD5XZH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008309</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPAT/DAPAT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZH3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07993">
        <property type="entry name" value="LPLAT_DHAPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT/DHAPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041728">
        <property type="entry name" value="GPAT/DHAPAT_LPLAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563:SF17">
        <property type="entry name" value="DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="7">
        <location>
            <begin position="194"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="581" mass="66118" checksum="A35489E3F9D78FD6" modified="2024-05-29" version="1">MVSKKPELKDTSPIKSVLSLPNTKTNQKPSKIIITKKQIIKSSPIPVDNTENDSDKSQNLTNFKPLRFRADPLSFIIKGTTELSAFYSGAGWRAYEEYIGTKILYPEYTLSIKKALLGSDRVKSAINKLLEEAPEKERQKKKHILWRETESIANKMIGFDILVKMYHQGIHIQEREYLRLKNVALYAQENNLSMIFLPCHKSHIDYLVISYIFFRLGLALPHIAAGENLNMPVVGNILKKNGAFFIRRQWGNDAIYLALMKEYLELLLERGHNIEAFIEGTRSRMGKLLQPKFGILKIILDSVLAEKRIKDCIIVPMSIGYDKVIEASGYINELLGTPKEKESLLQLLSNFNILSLKWGRIDVRFAEPFSLKDYIHSQIERRGPSFQPSSSPADKDLLLQSLGFRVLGDINEVSVVMPTALVGTVLLTLRGRGVGRDELIRKVNWLKREILKKNGRVADFGTMSTGEIVDRAIPVLKDLISVRSDLLEPVFYPNKRFELSLYRNQVIHLFISESVLSTALYATIKAGGPHQSQKIKYQKLCDDIGFLSSLLKYEFIFQFGGLEEVTSKTLDELVKRYSMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZK9</accession>
    <name>A0AAD5XZK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_001738</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000152">
        <property type="protein sequence ID" value="KAJ3222932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZK9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="29"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="11">
        <location>
            <begin position="225"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="264" mass="30093" checksum="1A14874F29CB42D4" modified="2024-05-29" version="1">MLFGYKLFPTEEVAANEEKNEQQKHLGEFQLLKTIGTGTFGRVYLSKDAKTSTFYAMKVLKKSEIVRLRQVEHINNEKQILKEISFPFIVDLICTFQDEKSLFMLEEYVVGGEIFSHLRRAGKIEMVMIPIHFREIITSSGHDTAVDWWALGILAYEMLMGYPPFSDEEVFGIYEKILGGKISFSSTLEPLAKDFIKRLLTSDRTRRLGNLKEGSADVKAHQWFKGVDWKALLRKEVIAPIIPIFSHPGDTVSKAIVLILDVGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZL9</accession>
    <name>A0AAD5XZL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ATG1</name>
        <name evidence="10" type="ORF">HK099_004439</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000312">
        <property type="protein sequence ID" value="KAJ3220210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZL9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048941">
        <property type="entry name" value="ATG1-like_MIT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21127">
        <property type="entry name" value="ATG1-like_MIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="11"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1042" mass="118612" checksum="5BFEA281A0CEA8EB" modified="2024-05-29" version="1" fragment="single">MSNQQVKIGEYTVGKEIGRGSFATVYLGKTMTNQKVAVKSIAKRKLNQRLQDSLKQEINILKNINHKNIVSLYDIIKSEKHIHLIMEYCMFGDLSGFIKKKGFSDSPNLYAGLHGGLNDFLIDNFLKQLANAMEFLRSHSLIHRDLKPQNILLAPNQGNNNFNSGSINNNQHPIRANSYSNKTVSTSPNSNYTMTYLPTLKLADFGFARLLPSQSMASTLCGSPLYMAPEILRGDNYDAKADLWSLGAVVFEMYYGHPPFKAQNHIELLKRIEQATSITFPDDEQEENRFNRNSVNSHNDVNILRNSKPIPILQNNFNNNFRSHTFNGTTASPPHQLSSPVRSNSSSTLTFSKENLKDFIVKLLKKNPIERITFEEFFLHPAVTGFKSPQFLLNQHIPQTESVSLKSKKSLSKLNLNEQIEFNNNNTYNNNKYSKSNDSAKTGVTPPFSSKYYGNDDEASLYSLSPAQVLGLRTNTGLAAGVLQSIEPKSPQIVTRHNLSPPVQTHSIHFKESEDSSKIPVSGPTGGVLMIKTPFPGYEVDPSVFLDNFNSHPQADVNKIFSNNIIVETTINNTNPLVKAKNVSLRNSLLIQDSKRNHSVKSEFEKKFVQIPISVDESNSTSSSVVQSGASFSKTRKESLKNNTVDSGEYVVVEKDLIKINWFHNENKIITGSNFSSNSPNNTNQFTELEERRSRYQGYNRDYSKLPDYMGQNYLHEIEDNLQKSNTSNVNFNAEKVEVAYPPFLFQKYENEDGKTSSHYLMPADMGIPFINIPEEEAEDGEKEYLYQEFHTLNLLAIHGFTIQIFGDEVFEILEHKENKENDANYKLNDQEFIKCEYVNLYLGALGLYHLAMEKATYIWNKINNDEGEINESLEIEEKSTSIENMEDDNFEKKPKVLTDEEIEKYKKQLGEIVEFIKVKFNLCLKKAENFENKNLSVSIERGRTCERLLYERALELSHAAGINELNSKDLEGCEIAYEQAILLSEAILNLPQQQQHRQQIQEKEHQELEKKKSYFSDGCTDEDRVVVEKFVAGLYVRCYQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZY5</accession>
    <name>A0AAD5XZY5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trafficking protein particle complex subunit 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004896</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000360">
        <property type="protein sequence ID" value="KAJ3218890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZY5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012880">
        <property type="entry name" value="Gryzun"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021773">
        <property type="entry name" value="TPC11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374">
        <property type="entry name" value="FOIE GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11817">
        <property type="entry name" value="Foie-gras_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07919">
        <property type="entry name" value="Gryzun"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 11" evidence="3">
        <location>
            <begin position="234"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Gryzun putative trafficking through Golgi" evidence="2">
        <location>
            <begin position="613"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="domain" description="Gryzun putative trafficking through Golgi" evidence="2">
        <location>
            <begin position="1028"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1245" mass="141331" checksum="486C52EEC0F7B907" modified="2024-05-29" version="1">MDQYPAEHLLNHIPLMATIGLKDPSPNQESVEAVNYLTTVKEALLNSTQNSHLSHNSQIVFHLNNFEKSHVFPRKNQNHEHSTLSPLTPSSPLYPDGLISTLWLIKHRELSPSVVVGFFDLFEKDGLSAEMERERDIILCSDINERRRAITDRGIKFAVVLILKFNSVGWNTRYEFKLGVLAEFRQEFDTSVKHYETAYQILLEILSNSVATSTIGGGTSYSSSGEFLNVNSTRWEEAKGLLDCLNYKICKLYFYIHTPISALSQFQKHLTNVKVLPEFSTISTGKTFLPEVQNLARKFVGGGSIECWAWLGKQFRLFGELVEHATNKLNLKLPYPPPGSVAGQATAIMNTLSGSAGAHSITGGELSTNVFGPFSSTNTSLVLQHAGFYYIASARCAEERWHKSREAENTSSLISPPPAARSSQVGRNEFDVQSARVTAEVKTLYFEPADIEKNVEHSVLVIELLTKAYEQFKFRKCGRTSLYLAGEIARLYYLGGKFDMALKFFDRINKTYRKDRWFYILKHILRETILCASKLGVFNVVIESLLELLGLGEDVVDELLFLLDGKDLNERQLLQKNGIEKLPSMDSSMDLFTPVQGREKVYFNSFDPENTSVEIDMNTINSFVDCSFQFKYPECVAGESMEYQVNFWARKGIEFTSALKFSKLLIKFSESDYDVEISSNIDDVDTNDQSKSDINFYNMCKNANNEKNFQVRSLYFQSGQKYTFQGLIKPKDSMLELKFTEAKAILQNSLKSREIILNFRVKDHINDNEKKLRTWITKDNNEIVKKLVLPGIGEVSALQINQRQPKVNIVLKHCTPAYIEEVHPVSVFVTNEENEEIDVFLDAEFKGVTSEGNDNSCFISSNYNSSKNFTKEDKAVNFVGGINLGTILPGKTSEKVLYTYIKLNPAEKCFKAKIHYNFTKKCRDLISSEEENNNYTGFIEKNFSFKKEEVLKMEFCIPFEYNFQFFSQTCNSFGTTKDNNGRVINELGLFTIEEDFFSEENATLEKSGLFLYFEKIISISVKCLGPWDVVFKEVYLTSANMAGVEVIPITPQEPSALIENQTHQSHSFLYRVKIKKHVEDENKNFLAGTLNIIWRRKPTSFDNLKNDEMYGTSSIAIPPINIGSDPVNIVVDLPAQINQGSLTSIIYLIQNTTMHVMELQTLMESNEGFIYSGLKQSLHKVLPFSTVYLSYNLVAINSGKLILPKLTCTRKSYSNDLSKAEDIPCPIKFNSQDISIFVKPVINWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZZ9</accession>
    <name>A0AAD5XZZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_003879</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000260">
        <property type="protein sequence ID" value="KAJ3220969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001156">
        <property type="entry name" value="Zinc finger protein 407"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050589">
        <property type="entry name" value="Ikaros_C2H2-ZF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24404:SF114">
        <property type="entry name" value="KLUMPFUSS, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24404">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="143"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="203"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="261"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="436"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="265"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="466"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3220969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="485" mass="55710" checksum="A4BFEF24F9BCBE8B" modified="2024-05-29" version="1">MNVLQEQSQSLTPAIILELQQFEEKTSIKNTVLNYYTQLSQINNWNQDQNSMFPISLKQLTQFVEHELNRVDKGEISIITLDIYLQTLHKHSIDLGFLDCVDIFNNTQLKEKIEKMRTKTCTTLQAPNVQIEDAEQEQQEQLYKCPHDGCNKVFQKSYNLNNHYKSHSAATDKRFQCEQCSYSFSRKHDLNRHVKLHENVKQFKCNHCHKEFARLDAFKRHLSPREPGKLSACEKRYRSNLVLNTNGVNALAQIPIIQSSNNGAQQQRNQIQQQNHMQHQNQIQQQQINPQQNHMRSPAQMQQQQVQIQQPWAAGAPTGNGQPIPNFHSGNNSNQFSQMILNNGPQAVSQVVNTQAVHQAVNQGEFVNNHSSISNHQNVNNPQPNNNNQVVNSNQHDHMRMTEYLVAQQQQHHQQHQQGGNINSENLVINEENVTEERIPDHNEVNAAKGENNNSTPPVDSGINKGENNSNRTSNIEDWNVVVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y021</accession>
    <name>A0AAD5Y021_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Drebrin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003791</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000253">
        <property type="protein sequence ID" value="KAJ3221074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y021"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11819">
        <property type="entry name" value="SH3_Cortactin_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF25">
        <property type="entry name" value="DREBRIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="394"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="528"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="145"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="316"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="585"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="464"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="150"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="191"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="585"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="620" mass="71315" checksum="D3ABB32D474D914C" modified="2024-05-29" version="1">MAHVSFPPDVSEVYRNILSYESNVNWACWQVTGVDSILRLLGSGGKIEIKHFYSIFLACLKDGGLEEVEEEFDEGKMQFAFCKVKEPISGLWKYVLISWCGDGVPVQKKGQFNVFVRDVELFFKGYHVKDSAGAKYSIHNERGPSAIDSFENSPTKPSHTQSTAFKSDSYSPNIGTKPSTSYTPTYGGKVVSSNSHQPSNIASAKQSTYIHSQNKVPTYSPTLNVNSEQVERERQRKQFEEDMKEKEERERIFSGQGVREERLRREKEEREREAAYIKRKEEVEQSQQTTKFQNFNNTVQGTSNLASRFQKDIASNGQSQNNATTNFNKFNNHDITPSRASVSIREEREKREADERARETALIKEREEVEKLQAFKAQQLVERMNKTIPTPVQVTSICAKALYDYNADEANEISLREDDIITDILKIDLSWWQGTVQGRTGLFPADYVEEIKADIAPPLPDRNLNAEGELAERERREAEKIEKQRIAEEKARQEEEYRVQAEKRPLQLEADRLREREQLAKEAEEERKRQAISLALYDYDAQEPNELSLRENEIITNITKLDEDWWQGMNDRGQQGLFPATYVEVQQQHPESPQQRHAPPPLPPKGFEAVAMYDYQGITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y074</accession>
    <name>A0AAD5Y074_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">HK099_003575</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the C-terminal section; belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">In the N-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000235">
        <property type="protein sequence ID" value="KAJ3221349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="359"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="18">
        <location>
            <begin position="1233"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="671"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1017"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1134"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1134"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1145"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1162"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3221349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="21">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1290" mass="145513" checksum="113C4AB7E543FF8A" modified="2024-05-29" version="1">MKELNKKFILVTGGAGKEIKLKKFESLRKIGYIGSHTVCELLKLEKNVIVLDNFSNSSVEALNRLKILTKKDFIYFNVDILDRKKVEKIFEKFEITSVIHFAGKKSVTESLKKTKFYYENNVNGTKNILEVAIAHKHCISFIFSSSACVYGKTEELPVTEDTLCNPPNPYGKTKLICEELIRNMCNKFNTSDQARRAHSSGLIGEDPIGIPQNLMPLVAQVAIGRRPCVQVFGNDWNTTDGTGCRDYIHVTDLAKGHIRALEKAEALSAPKNKTLAKTDIYWNCPIYNLGTGKSTSVLEVIRMMEEVSERKIKIEFGSKREGDIAEMYASVNRSEQELTWTAKLLASGRANKQQMFGPYYLYRTIGEGEFGKVKLAKHKDFMDKEVCVKLIKKENINNAVKRTKLMREISILQSLDHPFIVKLLEVIETAQYIGMVMELASGGELFEHILAHKYLKEKEACRFFVQLIAGVHYLHAHKYVHRDLKLENLLLDGNRNIIITDFGFANKSDGKDSLLNTSCGSPCYAAPELVISDGYVGEAADIWSCGVILFAMLCGYLPYDDDPANPDGDNINLLYKYILETELVMPDYLSEDAKHLLKRMLVPDPKYRAKMFEIFRHQWLKPYREILEESMNYTEQSVRELENSGNGKPAEAQTVPSIEEKSENIAEMEIDRKENSLNLSKPSVASEVEASKSKVAPTSSDEKIIEIETVKEVSESSLKAEDKMEIEYTSTPKVEDVNIKENDVVQNNIQMTGMDSTINSTEVVEMTIPQVVGNSPSSEQKEAPKVEAEASKKMVEDANPAVLNELPSPIVKKSSKSSQMSIELEIPAGNDLMNEIMLEVNNNYQNEEENSSTTIKPVINYKVSSSVLRKVPSVALHNKNSRNVLLNSVSKSSIKDLLIEKSPKISTEENSAEPKQKAVTEKNQPFGNKIELPEIPSFTKNGKSVASVKFPENQVEPEVTEPTKYRKSMDVYRTGTHERKGEKSKFTKAVKANEDPLTEEFPVASVEVRASSTRTVNIKSKKSKNQTKAKDNTEEYPRNSISTYTTATSVTKPYKLRYHSGPIDQRALTNRPPIQLLDDIINLVTEMGMYVRQSTSDSTSFKLKVVRPQQVLDVVDIKKHDTINSVNNLQEETLKSEDSIKDNNSKSTSDLRSLNRNKKSHQSYSSSMTEKPNTARIISSFPMSLIRKVKYMAKYGQSWNKGFDGKEEDDAHLKSRSGSINSLEGNGDFKDATLSESGEIKFYIELQKIKNLKGLYVVEFKRRHGDIWEFKRLYHELIVKLPLGEDGTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0E5</accession>
    <name>A0AAD5Y0E5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TM7S3/TM198-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008076</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0E5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="73" mass="8479" checksum="E2E931A1F81DD8EC" modified="2024-05-29" version="1" fragment="single">VIYGIDMFANAGFNVAVKSFLGNSNPEYYSQYNISRDVYIELVALVILFLLGVLVQFRINRNRVHREGYNKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0J2</accession>
    <name>A0AAD5Y0J2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000272">
        <property type="protein sequence ID" value="KAJ3220808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0J2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11921" checksum="F816DC35C9B8327A" modified="2024-05-29" version="1">MNLFLNGQLFIMFCKYGKVEGVKEFLSLGLNPAVDNQICIKLSSENGQFEVVRLLLKDKRIDPSHAGNFAVNKAIENGHLKVVNLLLENKKVKELYDTKKFCWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0R6</accession>
    <name>A0AAD5Y0R6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Methionine synthase</fullName>
            <ecNumber evidence="5 16">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">HK099_003708</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 19">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16 17">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="16">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="5 16"/>
    <dbReference type="EMBL" id="JADGJW010000246">
        <property type="protein sequence ID" value="KAJ3221177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046653">
        <property type="term" value="P:tetrahydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00740">
        <property type="entry name" value="MeTr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1240.10:FF:000001">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.20:FF:000002">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.330:FF:000001">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.280:FF:000001">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.280">
        <property type="entry name" value="Cobalamin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.288.10">
        <property type="entry name" value="Cobalamin-dependent Methionine Synthase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="entry name" value="Homocysteine-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="entry name" value="Methionine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="entry name" value="Vitamin B12-dependent methionine synthase, activation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050554">
        <property type="entry name" value="Met_Synthase/Corrinoid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033706">
        <property type="entry name" value="Met_synthase_B12-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007024">
        <property type="entry name" value="PRK09490.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45833">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45833:SF1">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="Cobalamin (vitamin B12)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="Homocysteine S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="Methionine synthase activation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="Methionine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 16 17" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="15 16" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 16" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6 16 20" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 16 18" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="9 16 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="13 16 17" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="21">
        <location>
            <begin position="64"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="22">
        <location>
            <begin position="417"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="25">
        <location>
            <begin position="709"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="24">
        <location>
            <begin position="822"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="23">
        <location>
            <begin position="973"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17 19">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17 19">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17 19">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="756"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="832"/>
            <end position="836"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="17">
        <location>
            <position position="835"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="880"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="884"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="936"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1024"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="1220"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="1275"/>
            <end position="1276"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAJ3221177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1313" mass="145875" checksum="8880FAF930399412" modified="2024-05-29" version="1">MLSSSPQKLTKNQKQRLKYRLKKKTSTACMIKSVVSDVPSNSIANENLAEYPVGKVPGKGKKLTDYLNSELQKRILFLDGAMGTMIQKYRFSEEQFRGERFKVHKKDFLKGNNDLLSLTQPEAIIQIHKEYLEAGSDMVETNTFSGTSIAQLDYHMEDLAYEINLVSAQLAKQACDYYTRLTPEKPRFVCGALGPTNRTCSISPSVENPSFRNVTFDELVEAYSEQVRGLLDGGADILLVETIFDTLNAKAALYAIDLMFDEGYDRVPILISGTIVDQSGRTLSGQTGEAFISSVNHVNPVAIGLNCALGADQMLPFMQNISKSTEAFTICYPNAGLPNTFGEYDETPEEMASKVIKFAELGLVNIVGGCCGTTPPHIKALHDALSPFKPRVRPTMDPDTLIVSGLEILRINKTTGFVNIGERCNVSGSKIFAKKILNGGYEEGLVIGRTQVESGAQVIDVNMDEGLLDGKAAMTKFLNYIASEPDIARVPIMVDSSNFEIILAGLKCAQGKCIVNSISLKEGEEEFIKKAKIVHRFGAAVVVMAFDETGQAVECDNKFDICARSYKILVEKVGFNPNEIIFDPNILTIATGMEEHANYGVEFIKVCSRIKKELPYAKISGGVSNLSFSFRGKEVIRQAMHSVFLYHTIKEGMDMGIVNAGTMPIYDDIPKDLLQLCEEAVWNLDIENNTEKLLAYAEKTGKVDKNAAAAEEWRSWEVEKRLSHSLVKGITKYIVADTEEARLLTEKYPRPLNVIEGPLMGGMSIVGELFGAGKMFLPQVIKSARVMKSAVAHLIPFMETERLARLESAGIDPNDPNESSYNGTVVLATVKGDVHDIGKNIVAVVLGCNNYKVIDLGVMTPCDKILKAAIEHNADIIGLSGLITPSLDEMVYVAKEMERAGMNIPLLIGGATTSKMHTAVKIEPRYQHPTIHVLDASRSVVVVSALLDPNSKEDYSLDVRDEYEDLRAEHYEGLKDRRYLSYAQASDKAFKINWKNVPTPVKPTFLGSKVLKDIDLSKLIPHIDWNPFFQTWQLRGKYPNRGFPKIFMDETVGEEAKKLHADAMEMLQKIIKEKILTGTAIVHFWPCNAVGDDVELYEDDTRVKKVGTFYGLRQQAEKDADNDEPYYCLSDFIAPKETSIPDYIGGFAVSVGFGVDEKCVEYGKQHDDYSIIMLKSLADRLTEALAEVVHLDMRKEYWGYAPDENLSPEDLLQVNYQGIRPAPGYPLQPDHTEKITMWNLMDVEKQTGICLTESLAMTPAASVSAIVFANPESKYFAVGKISKDQIENYASRKQMKVGEVEKWLMQNLSYECD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1K1</accession>
    <name>A0AAD5Y1K1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1K1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="199" mass="22351" checksum="E9D115CF87EED9D9" modified="2024-05-29" version="1">MSNAEVNDVTITKPPIHLGDIMNSREISISLPKGFTPLERILLTANGNVQRIISSYYNSPVTVEIISNQLKNSSNTDSVNVYEREVNLHCMNNICCNAVSTIKVSNEDYIDLIENQKVGVGQLFRYCNLLPEFVLLNVGKNEEKKIFFRFYILKSNGIEINIKETFPLNVFEFSSVKGEKGGIFTENLSTVNGLASYDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3D8</accession>
    <name>A0AAD5Y3D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha N-terminal protein methyltransferase 1</fullName>
            <ecNumber evidence="5">2.1.1.244</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">X-Pro-Lys N-terminal protein methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_001911</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54712"/>
            <dbReference type="Rhea" id="RHEA-COMP:13785"/>
            <dbReference type="Rhea" id="RHEA-COMP:13971"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138057"/>
            <dbReference type="ChEBI" id="CHEBI:138315"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54736"/>
            <dbReference type="Rhea" id="RHEA-COMP:13787"/>
            <dbReference type="Rhea" id="RHEA-COMP:13974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138059"/>
            <dbReference type="ChEBI" id="CHEBI:138318"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54724"/>
            <dbReference type="Rhea" id="RHEA-COMP:13789"/>
            <dbReference type="Rhea" id="RHEA-COMP:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138061"/>
            <dbReference type="ChEBI" id="CHEBI:138317"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. NTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.244" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3D8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008576">
        <property type="entry name" value="MeTrfase_NTM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753">
        <property type="entry name" value="AD-003 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753:SF0">
        <property type="entry name" value="ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05891">
        <property type="entry name" value="Methyltransf_PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3227455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="354" mass="40032" checksum="6D204B947924DD45" modified="2024-05-29" version="1">MNKTEELCYDAMKNKTNYYEIANKYWDNVEPTVNGMLGGFEILTEPDVKDSSSFIQEFVTGNNPRLNTDLCCDCGAGIGRVSKNFLLKYFKKVDLVEQCSNFLETAKKEIFVGEFSNKVDQYINKGLQEFFPEKQRYDLIWNQWVLGKTDSRSGVEDIMGIPDNEKNRKVSNSSLKSKRRLLRLGKRKSDPLVSTSMNNFDNINVNNNVNLTLPNASTTLNNNQIEKKNSSTWTREHNNNVPAITILGIPASKSQQSDTGSKEHLSTSPNTINLVSNNTTQNVKAKKNLNIFHRNKNSNANNSNNITNLAASSNENPFIVRKSISSGCLKEGKPILDLEEDYLQNEFYHQIDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3Y2</accession>
    <name>A0AAD5Y3Y2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3Y2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033781">
        <property type="term" value="F:cholesterol 24-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006707">
        <property type="term" value="P:cholesterol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039983">
        <property type="entry name" value="CYP46A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24293:SF0">
        <property type="entry name" value="CYP46A1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24293">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 46 SUBFAMILY A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0349">Heme</keyword>
    <keyword evidence="2 3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042202472" description="Cytochrome P450" evidence="5">
        <location>
            <begin position="21"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="3">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3228480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="58951" checksum="48667652E7462092" modified="2024-05-29" version="1">MKNLVTVISIAAITVFLITTKKKKPTYNNIPVYKGGVFFFGHLFQFLKFGKKKKVHELIEDFNKSDPIISYYFFNVEGIMTSKAELIRGVLNSKNFVRDDFAIKAFEGISKFSLFVLPTSDLWKKHRKMIQPAFAPQHLERSFNVTSEVCDRLFALIEDGSNNVPMHDYLNYISCDVIGKVAFSYDFEFTNSIKNLKDPKFNVIRQFDSIASNYEKNFSELKFFLAAVGMRIATPKVLWGLLGAYPDKGTHANISNTVRRIVQEKKSGVSENKSYAEAAVGKWEMDVLDRLLENSSETESDPHESEEAPFTDEELCDEIFGFFLAGHETTANSLSFMLLELTKYPLIAKRLTEEIDPVMNDGNFAFQKLGELKYLDCFIKESLRMHPVLPGIGKVASKDEFLGEYFIKKGTPVMANLMCVHFSEQYWDKPKVFLPERWENNFTPVPGSYAPFGDGPHNCIGQKLALIEMKVVLSKILHTFDFVPREGQNFDVVYNLTMRLKDGIYLNLKKRKHVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSD4</accession>
    <name>A0AAD5TSD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002220">
        <property type="protein sequence ID" value="KAJ3198964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSD4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="182" mass="19759" checksum="6FCFB8C40968991D" modified="2024-05-29" version="1" fragment="single">KKNKIFHIQSNLKKSKYQSEIIEKSKDGLEGGIVTLGTIFSNQKLESSVSDDGATYVSKSFDDSEINVNSSSSSSISDCRVEKILSISLSSPPTSMRSPPEQQVITESNILEAPPRFQSTAGMSLRLGEMNTLKKTNSTVSGSEFSWDNLTKGLIGSDCEKLSQKLSVKSSNSKETDCTFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSK6</accession>
    <name>A0AAD5TSK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002097">
        <property type="protein sequence ID" value="KAJ3199509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSK6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="241" mass="26548" checksum="149C7C625AE29C51" modified="2024-05-29" version="1" fragment="single">KLLYIVLMLISNSLQDNTHQRHIRQSKSKLRLISMSSSSSLEISSALSDVNSLSSSTTISTSSSFSTTTTFAAIVLSNSTIFSTIKNSQTIPTFFSSESFSTPDSLPTSVSLTEGNNNFLTKTDDKFQFYLILSIAVGGILFILILLITLFVFLRKRNKGKNELFCTESDGSVSRTHSIRLNSANPTKAFSVYEDGSNKDSSSKSGGSFRRHTFKSANSEGILDEWDKSISEDDEKNLIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTA9</accession>
    <name>A0AAD5TTA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001690">
        <property type="protein sequence ID" value="KAJ3201671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="409" mass="45217" checksum="2DBEBD357FDEDC69" modified="2024-05-29" version="1">MDNSIMIPQPDEKKMTTSLSKEEINTVETKYSGVNSVKQMFEKFNSNTAPGLVSKPSINYKNKQPLASKIPIPIKSETEKMNATKPLASETLKAEDDSTTNKELSTFSSESKLAIKPSLLEKRPSKSYIDSAFKKTSSVETIKIDQNKNFTQSLQEQHENLLASLNEEQSNKSAVLVSLNVEQQSNNNTVDEKSLSRSELSINTDTPSPLQQNSTQNQISDTTPVTPVSKTRRETSRIKNQGKNEVVSGDFRWMKQSPTKGNVSSSVSDFSGAQNTSTCCSPVKQLATSPQDIKKPYVAPGTPRKVLKKTNEPPPQLAQTKKKNLATEKKNLNIDIPIEEKSTTVPEPSMHIHGEEYSKIQNTVRNLVGLKSIPTGQFSHNKQTPTGGFVHRNGTVKDRVKNLEGNGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTS8</accession>
    <name>A0AAD5TTS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA-ATPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001359">
        <property type="protein sequence ID" value="KAJ3203947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTS8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018631">
        <property type="entry name" value="AAA-ATPase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09820">
        <property type="entry name" value="AAA-ATPase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA-ATPase-like" evidence="1">
        <location>
            <begin position="13"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="53" mass="6024" checksum="157CFAC56E3B4929" modified="2024-05-29" version="1" fragment="single">MNQIHVVKGDSLPIGVDSFRCLITEKRTFVDKTLLIHEFINSSSLVSLVLRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU82</accession>
    <name>A0AAD5TU82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001417">
        <property type="protein sequence ID" value="KAJ3203524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU82"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="304" mass="34886" checksum="1583E8ACF8EBCA01" modified="2024-05-29" version="1">MFKIGHLISIDIKYNDGFSKVFNNLKMEYREILYFILDKFQVEDEENLDPIDLTPPQLKFGCLEFLIAILDCSDAAECCIYNNTSGANLAISIISKRSRDDKTYHALYENLMMNDYFLRIIKESLDPNSSIDDQMMALEVMWILCNSKNNFTILQFLCETQLLQYTLILLLSHGIDQNVKFYAADCLKTVLNWADNPATLFSNVPYLEDECKADNFQITKILILSFVSPALQNSFSNSEIVDILISSSYVLQMLISIYHRHKCANTLSVAFLLLDCFNSLCGINNSYSSPSEFDIIKEELLYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUD7</accession>
    <name>A0AAD5TUD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kynurenine--oxoglutarate transaminase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CCBL2</name>
        <name evidence="7" type="ORF">HK099_001081</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001282">
        <property type="protein sequence ID" value="KAJ3204612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUD7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000024">
        <property type="entry name" value="Kynurenine--oxoglutarate transaminase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00753">
        <property type="entry name" value="ACCSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="13"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3204612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="389" mass="43592" checksum="D12B79607E76193D" modified="2024-05-29" version="1">MLGFPTLNVEKFITESLNEAAINNTSPLIHQYARSEGHPRLVQSLSKFFSPKLSRTIDPLSEIVVTVGATEAIYSTVQAFVSPGDKVLLMQPYYDSYPASILLAGGVPVLTSLKPKNLSATSAEDWELDFSELRKILETNKIKMLFLNNPHNPIGKVFKKSELLKIAAFAKEFDFLVVADEVYETLVYSDNSEPFVKFASLPDMFERTITIGSVGKMFGVTGWKIGWCISSPEIIKSIQLVHQFVPFSVTTPIQEAVAICLEKTEKNNFFSSNLNKYENLRDKLFNNLKEVGLSPMLPQGGYFILANTSSVTGFESGDKRGRDYDVCKYLTEKCGVTAIPPAAFYDEKFTGDSERKKTAGYLARFAFCKSRDMLDEANIRLKNYFNKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUS4</accession>
    <name>A0AAD5TUS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000366</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001084">
        <property type="protein sequence ID" value="KAJ3207022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36127:SF1">
        <property type="entry name" value="COMM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36127">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="309" mass="35994" checksum="096CAFBD59DD35E3" modified="2024-05-29" version="1">MCESDIPRLIGRTVISDNTNFNTSTSDSDTDSDFNKLLNIVERLESDDVYQTVKEFLNSRKMYTISDNQTIDKIEIKNEKEELDSFLLNTLFSDILNFENCKTKRLLQTINQGIVLSSMPYLYDNVLSKYNLMVKDVRGKDGWKIRIHFHYTISNEEIISKRKNQQNLKSVNVVHIRKEQSLIKSLDDTTPDFILEWEVSLTFDHTLKLEGVFLKILNVKILINNEYKTLPRCGKEDIENKSLDLNDSNKKKSETDFLRNVFFGGNQIFIEQNLNEDNGENNNDFSNIKKGFVKLFSQKKVEKNTSDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVE2</accession>
    <name>A0AAD5TVE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000935">
        <property type="protein sequence ID" value="KAJ3209528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVE2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3209528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="74" mass="8506" checksum="BEC588007DF8098F" modified="2024-05-29" version="1">MRPTSVKINLDSFKKKDLNSIPTQVDQGEKDVNNFIKFEMVKDDAKIEFSDNLLLEPELIVVTGPKLQRKRSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVF0</accession>
    <name>A0AAD5TVF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Guanine nucleotide-binding protein G(O) subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GOA-1_2</name>
        <name evidence="7" type="ORF">HK099_008469</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000930">
        <property type="protein sequence ID" value="KAJ3209637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVF0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="201"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3209637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="289" mass="33633" checksum="52E6C78DAB82E9A1" modified="2024-05-29" version="1">MIETDNKLELLDVEKKLTIKEARKRSNQIDEQIRKESNAKEKISKLLLLGPGDSGKSTFNKQMRILYGEKFTEAEKEHYKKSIYENIIKTIQDIITGLENTGFIFEDEKLKECAKLIKEFVLNDSISPKIVNSIITLWKENSIKDFHKRDGSYSHTASIASYDQTLVEDPTINRMRDAIKLFDYVCNNKLLKKTAMILFLNKADLFEEKIKCIDIKKYFPEFGDRQQNLKTSKIFFRKEFECLNKAKGKNIYVHFTTNTDSKLMRFMITAVTDIVVKIQLSESGMTTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVJ5</accession>
    <name>A0AAD5TVJ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000894">
        <property type="protein sequence ID" value="KAJ3210380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVJ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3210380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="261" mass="29898" checksum="B6852D9FF719A6B3" modified="2024-05-29" version="1" fragment="single">MTVSYLDLKSTSLWDERGYSGSLSRDYTPMGLESVSKTTGTDEENRVNIKPDLVESIVFRKGSSIKHINLPNDILILCEKYWVDMLKILTLLMEVSALSLNLEENFFKSFFKNPSCSLRLAFYPKIEKIKEGTEIDYFPQTRYGAHTDYTGFTILRQDENPGLEVLINNQWIPVPYIPDSYVINSGDLIQRWTNDVFKSNLHRVSKPKDANKDRLSIVFFTGPDDDSIIIPIDSLCTIENPSKYPPISAFDHLMHKLNVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVM4</accession>
    <name>A0AAD5TVM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">DBP2</name>
        <name evidence="14" type="ORF">HK099_008139</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000864">
        <property type="protein sequence ID" value="KAJ3210965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVM4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17966">
        <property type="entry name" value="DEADc_DDX5_DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="13">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="201"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="404"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="562"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="170"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="571"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="595"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3210965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="612" mass="68671" checksum="2A5055B56AE28A1F" modified="2024-05-29" version="1">MSDRRDNRRDDRDRRSSPRREDRDRSHYQHSNLQPNYYQNSYTNNHSSQPISSVTTYSQPSSYSQSSYPATNSYQSVPFQQSGGYNQGGGNSYSSQPSSYGGNATYNNNTSGLGANLTKVDWSRESLSKFEKNFYVENPEISKMSQSEVDEFRRKFDIRINGSDIPKPVSKFEQIPFPKYVLQEVLKQGFKAPTAIQAQGWPMALSGRDLVGIADTGSGKTLAFTLPAIIHINAQPMLRPGDGPIVLVLAPTRELALQIQAEASKFGASSRIRNTCLYGGVGKVTQIRDLERGCEIVIATPGRLIDLLETGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVEQIRPDRQTLMWSATWPKEVQSLARDFLKDYIQVNIGSMELSANHQVKQVIELCTDADKKTKLIKLLESIMSDTDQKTIIFTATKKMADEITYYLRQDGFGALGIHGDKKQNERDWVMNEFKTGKSPILIATDVAARGLDVKDIKFVINYDFPNNVEDYIHRIGRTGRAGRTGTAHTFFTADNAKSAKDLIKILEEANQEVDPKLREMAMYAPIKSSYRGRGRGGYQSRGGYQSGYQSKGGFQGRGGFQSSGIYGQQPNGATSYQRYTPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVZ0</accession>
    <name>A0AAD5TVZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001827">
        <property type="protein sequence ID" value="KAJ3200833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVZ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042087043" evidence="1">
        <location>
            <begin position="18"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="58" mass="6096" checksum="283A6577C8DF27C0" modified="2024-05-29" version="1" fragment="single">MLSKTITAILLSVVVNASPAVVCNKMMPTCNTIRCASGFTCQVLPQTEFSCAKAECVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWB5</accession>
    <name>A0AAD5TWB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DBP6</name>
        <name evidence="11" type="ORF">HK099_001974</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010001611">
        <property type="protein sequence ID" value="KAJ3202168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWB5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17956">
        <property type="entry name" value="DEADc_DDX51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="69"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="331"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="379"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="600"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="379"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="608"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3202168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="650" mass="73445" checksum="452C9A7E43292926" modified="2024-05-29" version="1" fragment="single">TGLPEWLRNPIIYESKNNSKVEKEVKKIKKQPFLEYNFSTATEQNLKKANFVKLFPVQQATFSLLSKSTLANKFTSDVLVSAMTGSGKTLAYAIPIIETLIKRIVPRIRALIILPTRDLAIQVKQSFENFKKGTNLQVYLITGQQNFETEKHHLNSVKIDILISTPGRLLDHIKEGCVNLEHLRFLVIDEADRLLNQKYKDWLENLFNYINLKNNDNLTSTEKFNKNINFDVDEFGLPISKVKTFRYNGFNDLEKFDTGIISHYTPLQKLLFSATLTRDPSKLAKLNLNNPKYIQIINDDNDKDSNIIFQTPENLTEKIVVIKDNAKKPLILLHLLIDLKLTGVLVFAKSIEAAHRLAALINIFNKMLTEKGDDLTSSSEASSFSESDSSSSSDSLSDADTSGDSGSNFKNKKLTKKKGTTNSTSIKKKIDSEKFLFVAKAFSSTLKASKKKKLLKHFKNKKINCLICSDVMSRGMDLGSCVSTVINYDIPSSTQGYVHRIGRTARAEREGLALSILEFSQVKWFKKEILSKVNRGNKDLHNQLKIDEKSIVEKYLETFLKSLKIVGEMVKGEGTTKPSEQNYKNSVKNFIEDVISDVENSDDDDESLSQSTTKSTSGSKKFGNYKNLYDIPTKSQFNPVESILKNLFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWM3</accession>
    <name>A0AAD5TWM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007917</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000812">
        <property type="protein sequence ID" value="KAJ3211814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWM3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016211">
        <property type="entry name" value="Glu/Phe/Leu/Val/Trp_DH_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722">
        <property type="entry name" value="LEUCINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722:SF1">
        <property type="entry name" value="VALINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000188">
        <property type="entry name" value="Phe_leu_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="5">
        <location>
            <begin position="157"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3211814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="389" mass="43141" checksum="BA5DB93FD32DE2E8" modified="2024-05-29" version="1">MVMKVFLCKLERTVILYNLLLFIGPIGINKKNKIKLNLCYRGPGAGGVRNWVYDNMLNFFEDGLRLSKGMTHKNALAGIWWGGAKGVMARNSGKGLQTFDSKEERKTVYAEYGDLMTSLKGCYHTAEDVGTNTEDMRNVFSRTRFTTCIPADVGGSGNPSVPTALGVSIGIEAAFNYLNRKLVDATIAVQGTGHVGKPLIKFLFSKGVKKIIATDIDEHRKEDILKEFKDFNFELRIVKKDDNSILFEDVDCVAPCATGGTLNSETIPKIKAKIVCGAANNQLLNFSTDDVLLKKRNILYVPGNGTLRNDPNIEKHLGRTWENSIYLLCLKVFKESENNDKETTNTISLKIADKKSFEVNPIYGHRGKVIIDALRKESTSVLEGTSAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX60</accession>
    <name>A0AAD5TX60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000682">
        <property type="protein sequence ID" value="KAJ3213726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX60"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="727"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="645"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="730"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="772"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="954" mass="109499" checksum="5996ED08B92326EB" modified="2024-05-29" version="1">MSCFEGKLKEAVNEVQKILDTTRNPQLPSEVIHKYEDKFLLAEFITNSALAAQLNVLRHLNFNDENLKKMKKWSDSNKTVTLCFVRKEYCDFVKEVQRTLKPTHSVQSESTITQTSGSSNAPENKTTISSSVVTTVTEYIYKVKEEYAIYCYQGTDKSDSIKLKENILEAEIVTTSKSTPYPQLSETSPLEVNITWFFKNVDENFQFNFAINRNDLKCKTPTNNKDIKGAVEFFGNFHTWSYAVFDFLTSTAKKEVGFLDKHLEDFQMINCNSIFVPIFPLFEDPQQNSTMDGSLLMLEENQQLAVDRNSSDMGPPNSILFSAGDVNLFLSQQNKSLNEKLEVLERSFCKNRKLYTPAEAKLSVILLHSNDIDTNFEEGVEYLKEMLTKQLIQAIGKVINPVDFYNFMKYHNRKLFKPEYEQKPFCVSIRRPNHSPEGVVSVETSLNSFKEGKQESIYTSVRRLPPHTMQFAINASTNVEFNGNRFIHSWVSYSFENSPIKELNLVARARQFSSFILIVGRIVSKDVFDPKAAIIIENKDELEIPLILESIASATEFKDYISSLSPEQQRFAKAFREQQLQSTMFGILIVQIKPQLEKLLKIPNDSLTKEIQLTQDLMELFIKYQIPSDLLTFDGNESLDQSTKLNAVKEHVARIKEMLNNSRKKELEHEKELKDLELRNKERLKELEARKQREGEEILGMTATRSMVPNPLRNYRTTSRCVDQSYDHGPSFQPTSQSFFQSTASVPPSGNMETRKMPKKGKAAPPPNFSGAKEEYKNLPEKRKQNDSIDNSRKNFYELKEGGSGGYDFTNIPKTMDDKFEEMKSKHTKPTIIEIGKIWKKKSNRSFLREKTENVEIHSEGQRKELNAAFDLLDAISRSGSLSLEESELHVIISTTHNFEESVIDTVIENNINPIEHVEKSLLLVNSVVFQTNTENLLKDDQVDRIKLISNELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX95</accession>
    <name>A0AAD5TX95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RhoGAP-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000927</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001237">
        <property type="protein sequence ID" value="KAJ3205066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX95"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="446"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="733"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="184"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="588"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="672"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="945"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1008"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="216"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="598"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="624"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="675"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="688"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="951"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="964"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1008"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1038"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3205066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1120" mass="127286" checksum="9127AC51C449D5B0" modified="2024-05-29" version="1">MNNVYEPVSGTMQTQQNVDLLLSNVILERNTLRQQNEQLWKIIEKQKLQIAQLQEFNKEMNGRKSINGRERQKSGHPPSTQERYKIDQQLPIIAPAKGSSSNNSLQKTPTSTALPAVPSANQPNYLGTQSYSGGNSGIINDNKNINSSPSLSADYNYGGFLPKLDTQNSFNKLTKTEFDAIAARDSATRESECQNPPTDTRRLSSNLKRPRFINDELTQSQRNARENSFSESNNVEQQPPELSSDNSKGVMDTTSDENEETLTKNDPETTIELTKSSSSNTLLKLNPESVENFENINITFLDQSKVKKSGGKEQHLLTFKISANDAQKTEYWRCEKLYSDLFVFDIKIHSSHPQEILSQLRRVPEKSLFQGNLSEQKLIHGKQSLDNYLQKLIKVLSTDSDVLNFFKTDIVEEKSKVLQDDEKKYTKSNDEMDTKESSNPAQKEINLFKEGYLTKKGKGFGGYTWKKKYFVLRSGLMDCYETNDTTTQTTGTIKLKYCTVEKKIGHESDPELKFSICITEYKKDTFKFKANPPLQDAKVNCKYVLHCVNEDDCEEWISSIQENINLVRPAAIDTIPLEKNNEKTVVSNGLVSPEPPEANENPEQATAVPPATPPISPTQPLNLRPNSPTRHFLSTPSNVKDNQIGKVDENERIMKQATLPISSIFDNGSLPTTNLSQYQQGSSLSLNKNKDGKRKDGNEKKINKRMTNFFSGKKKNEKVTSDTTEPARLVFGVSLEKCLQISKITENFELPSIVYRCIEYLDAKDAIKEEGIFRLSGSSVEIQKLKERFNNEGDVDLVNNGEFYDVHAIAGLLKLWFRELASPVLTSEKQKDFVQLLEIGDRNEKIKALKKLCSQLPRSNYTLIRSLVGHLIKVVQNSAINKMTVKNVGIVFAPTLSVPAGIFTLMMAEYDIIFSWDGLNESEIERQQFSILPLETNSYVEENNKNNLESNNEENNEDEEVLVRKRPPKPGGRKKVDASHSMIYESDVVNIINTENYENNVEKVVEERDSTVLLRPHEPFRPEGTNEENVKRPRSSKIQQQILRQSSTQQNHQKPQKQQQQQQEFYLRQDTMEDKEFENETIVDHANILQKNEEFHFPNFQVSGSPDSSVKDNELLVIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXB1</accession>
    <name>A0AAD5TXB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001220">
        <property type="protein sequence ID" value="KAJ3205264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXB1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="82" mass="8070" checksum="535266CE203DE642" modified="2024-05-29" version="1">MGFTGGSGSPATGGNGSPATGGNGSPSTGGNGSPSTGGNGSTAGDNRSSGNGRSNKYAKLPIKTIEFMKYPLKMHYNLMQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXK5</accession>
    <name>A0AAD5TXK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000628">
        <property type="protein sequence ID" value="KAJ3214351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXK5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="239" mass="27813" checksum="689E23B17D1C4FE5" modified="2024-05-29" version="1">MDNSINCNFNARFALERTEENSNFFHKSFRVKSNKFQKKDSAKDLTDSTEYSEKSEYFTECPSSNKRRRNKIKKQLHRPQFNQFSPQNSKDNEKCVKVSGNISSQEAYCSPNKTNEAEFSNDAEQGWISIKDIFVACSDKCRNNNDTQKSQIQKHRISYSTITKITTVENVDSSFTSKGTCMDKCKSSKGDTLFKERCYVNKESKFLHERWNEMLKNAMPLNNIVEQNNADSVYYLHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXM2</accession>
    <name>A0AAD5TXM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EF-hand calcium-binding domain-containing protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EFCAB10</name>
        <name evidence="2" type="ORF">HK099_006632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000587">
        <property type="protein sequence ID" value="KAJ3214849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXM2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22976">
        <property type="entry name" value="DD_EFCAB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049760">
        <property type="entry name" value="DD_EFCAB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056587">
        <property type="entry name" value="EF_EFCAB10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039879">
        <property type="entry name" value="EFC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21847">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21847:SF1">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24548">
        <property type="entry name" value="EF_EFCAB10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="70"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="128" mass="14440" checksum="CE6A24DB0FA5F34D" modified="2024-05-29" version="1">MAVKPAAALKISKQLDESEEYLKQKKVKQLIQTLASSVLFHEPENVKEFMIKLLEEMKTYKARGQSYPFFSKDDIIAHFKVLDVTGKGYITTQQYIEGLKTIGIPNVNVNPKGSLQNKISCEVYVADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXR4</accession>
    <name>A0AAD5TXR4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRELI/MSF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000864">
        <property type="protein sequence ID" value="KAJ3210966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXR4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037365">
        <property type="entry name" value="Slowmo/Ups"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11158">
        <property type="entry name" value="MSF1/PX19 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="203" mass="23184" checksum="CF006F3B029A1B17" modified="2024-05-29" version="1">MKLLDIQHTYSYNWQTITTANWRKYPNELSSHVLSCDVISREVDPSTGILKTERLLKCKQNVPYLIRSLATIPEVSYFREVSYLDPKTQTYTATTINLSLTNLLTIREICTYKPDPSNPNKTLFQQQCMTTAGQSFSAFGKYIEDAAIYKFGSNASRGRAGLELVINKVLEEVRDVEDKLGRGLETLEKDILGLFEEKNEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXU5</accession>
    <name>A0AAD5TXU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Single stranded nucleic acid binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SBP1</name>
        <name evidence="3" type="ORF">HK099_006828</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000612">
        <property type="protein sequence ID" value="KAJ3214552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXU5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13179">
        <property type="entry name" value="RanBD_RanBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000018">
        <property type="entry name" value="E3 SUMO-protein ligase RanBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045256">
        <property type="entry name" value="RanBP1_RanBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF87">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE RANBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="21"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="177" mass="20611" checksum="ADBF7CEC996090AA" modified="2024-05-29" version="1">MSEKEVKDAEENEEVVSPDVHFEPVVKLEQLDEIKTFEEDEDTTFKMRAKLYRFNKDDKEWKERGTGDVKFLKHKVTGKCRILMRRDKTHKICANHYITAEMSLSPNLGSDRSWVWNTLADISDGEPSQDTLAIRFANSENAEKFKVAFEQCQADNKSSANKKSEEKKTEEKKDEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXZ2</accession>
    <name>A0AAD5TXZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">54S ribosomal protein L23, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MRPL23</name>
        <name evidence="5" type="ORF">HK099_006627</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000586">
        <property type="protein sequence ID" value="KAJ3214876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXZ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3214876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="168" mass="19216" checksum="06227B6D1E5E3C43" modified="2024-05-29" version="1">MNKGTGLQYTRVFHLVDAKDKILGKLAARISIALRGKYKPFFNPAVDHGDFVVVINARHVALTGNKGAQKTYRWHSGYMGGLKEVKYPEFVLKHPTAPIERAVYGMLPKNNLRKVFMNRLKVFPDEDHPYTANILKHHDVEYERLLEKISKQENSPNINKSTKKITGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY17</accession>
    <name>A0AAD5TY17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Anamorsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CIAPIN1</name>
        <name evidence="11" type="ORF">HK099_006635</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the anamorsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000588">
        <property type="protein sequence ID" value="KAJ3214841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY17"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007785">
        <property type="entry name" value="Anamorsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046408">
        <property type="entry name" value="CIAPIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13273:SF14">
        <property type="entry name" value="ANAMORSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05093">
        <property type="entry name" value="CIAPIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anamorsin C-terminal" evidence="10">
        <location>
            <begin position="38"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3214841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="123" mass="13545" checksum="DCDD792DFC9BDC24" modified="2024-05-29" version="1" fragment="single">IKEKEKIWKINVNDNDEEQIDEDDLLDEADLMKPTLKTASDCGSEVVKGKKKACKNCVCGLAEELDREEEAKIEVIKPKASLPKSSCGSCYLGDAFRCDGCPYLGMPAFKPGEKVTLSLTDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYB1</accession>
    <name>A0AAD5TYB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006353</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000540">
        <property type="protein sequence ID" value="KAJ3215470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYB1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052735">
        <property type="term" value="F:tRNA (cytidine-3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF11">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="295" mass="34267" checksum="6C5D5A175D058D0C" modified="2024-05-29" version="1">MVLEKASDKKLQSSLSEFGARILTENDNIFEHNAWDNAEWTAEQEEEAKLKISKQYEGRLTIEEVLKHNTNPNEYWNTFYSKNADKFFKDRHWLSVEFPEVLKGVLNHPKEEKPINIMEIGCGTGATVFPLINETKIAHDANVYFYATDYSTTAVDIVKSNPLYDESKCKAFVYDITSTSSPEHVEFGTIDICSCVFVLSAIHPDTWKIAIDNLFKLLKPGGIVIFRDYGRYDMTQLRFKSGRLIDDNFYIRGDGTRVYFFTIEEIDTMFKEKFKIEQNDVDRRLIVNRAKKIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYN1</accession>
    <name>A0AAD5TYN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000508">
        <property type="protein sequence ID" value="KAJ3215953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYN1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27834" checksum="31F1400ED06A74CF" modified="2024-05-29" version="1" fragment="single">VGNIKNVMDYTSSILFADTKFLMPVFECGVGKKDFKNQKVLDNNNEQACIDFCRENFPGVPYTATNCDNCYCLSNKEYKSITKGNKSECNIKCKKKDSEFCGGENAYAISYVYNCYKVNDDPNLFRHLACTDFIVKMDQFALSDGNKCYCSVYRFGVREDAVEHTLCYKDCTGIDEQICGGKDTYSTYTEKMDDKLHCAYNFEEYDRILANKKYHKPGVWRGTLEGCAKRHNFEYESISEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYU6</accession>
    <name>A0AAD5TYU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007293</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000699">
        <property type="protein sequence ID" value="KAJ3213546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYU6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040031">
        <property type="term" value="P:snRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039772">
        <property type="entry name" value="Bin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010675">
        <property type="entry name" value="Bin3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024160">
        <property type="entry name" value="BIN3_SAM-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315:SF0">
        <property type="entry name" value="7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315">
        <property type="entry name" value="BICOID-INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06859">
        <property type="entry name" value="Bin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51515">
        <property type="entry name" value="BIN3_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bin3-type SAM" evidence="7">
        <location>
            <begin position="43"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3213546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="304" mass="35653" checksum="9F2CE7AF1EC61B4B" modified="2024-05-29" version="1">MISKYEIIIKKNDNKRVRENDFLSNDDLKGEKDNTEKNEKNVDPRLTVLEKSFFENKRVLDIGCNSAFLTVQIAKYFRPSYIEGVDIDPTLINKAFKYLNFQASLMKPVKKSDGEEFSVVDDNKKDFKEKNTSLIEVNKDVDDLKHENNFEYFPISGPLTYGTMPIIKSINATSFPQNVHFRTGDFTKQPLEINQKKYDTIIAFSITKWIHLNEGDSGLKLFFNKIYFSLIKGGIFLMEFQDFDGYKKKVNNFHDKLKSNLKNIKFFPVDFKDFLLNEVGFRDFKFLGKPSQKNFCREIYLFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZA9</accession>
    <name>A0AAD5TZA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000394">
        <property type="protein sequence ID" value="KAJ3218122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18090">
        <property type="entry name" value="Arginine_MT_Sfm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03181">
        <property type="entry name" value="GST_C_EF1Bgamma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000006">
        <property type="entry name" value="Elongation factor 1 gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007364">
        <property type="entry name" value="SFM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517:SF1">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04252">
        <property type="entry name" value="SFM1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="10"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="96"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="474" mass="54223" checksum="D696D754A0C72268" modified="2024-05-29" version="1">MPTSTITNSFDGKLFTLKDSSKARTLQMIANFNKINLEIIYVKDTADFKETNNFNDSFPLGKLPAYQSNDGFNLHQSDAIAHYLASKEGSKLNGTNAKEKCLIQQWSEFANVEFESTRAVLLFPMFGWTTANVQFEKKAIENLNLSLEVLNEHLLNNTFLVGERITLADIKLCSSLLDFFKFYFNDAFTSKFKCLTRWFNTIANQDYVKEVIGSTKYHKLKEIDSKPFKSDSNQIALGKELEGKNTAETDTLKTNLKKKSEKQEESLRNQNQTVLNKKKFTYIVEHMEENITDWVKIEYLHMVDWVGKNNLLITHCDDEVMKNLPKNINGTYFDVLNKQLGIEKKKVILLDPKAKEELKPSDAENFDYLLFGGILGTDPPADRTAVLRKMGFACRKLGPVQLPTDQAVIFSHLILEKKFNLEEIKYVDSPEIKTGTSETVSIPMRFYSRDGKNPVLAPGLKELLKSQNDFEIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZD8</accession>
    <name>A0AAD5TZD8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipid droplet-associated serine hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005463</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. LDAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000426">
        <property type="protein sequence ID" value="KAJ3217471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZD8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019915">
        <property type="term" value="P:lipid storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019363">
        <property type="entry name" value="LDAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390:SF0">
        <property type="entry name" value="LIPID DROPLET-ASSOCIATED HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10230">
        <property type="entry name" value="LIDHydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="35196" checksum="A6681B4BCC60F99E" modified="2024-05-29" version="1">MSIEYWKVNNELNEVLYYKAQSKTPKLVLLLIPGNPGVVHYYKSFLEVVFNLTNKRVDIICVQHLGHAVKDKERKYLLRDQVDHKINFFDYLRKKKYKSLKNLKFVLSGHSIGAYMAIELYQNRLHCNIIKVIPLFPTLHSMLETPNGKKLNLLFNAPFRNIASTIVSGISFLNELFPFVVISIIRFITKQSFTNALITCNHLLKSNIVYSALYLANDEMKHVTEIRTEVIEALTKKQEIFTFYYGATDEWSPIDHYYQMKMLLPNAEVYLCEDECPHAFVLEHGDIIGKKVANWILNQKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZG9</accession>
    <name>A0AAD5TZG9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GDP-mannose transporter</fullName>
            <shortName evidence="9">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VRG4</name>
        <name evidence="10" type="ORF">HK099_005380</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Golgi apparatus membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Endoplasmic reticulum membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000415">
        <property type="protein sequence ID" value="KAJ3217682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZG9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3217682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="373" mass="41344" checksum="669A0F34B668B36D" modified="2024-05-29" version="1">MPAQKGQGSVLAIISYCLSSILMTVINKFVLSGLDLKLVCLLLVAQNLTCVVILEIFSKLGVLSHRPFKSQEAKKWFVVSLVLVLMIYTGSKALKYLSIPLFTVFKNLTIIIIAFGEKTYFGGSKVTGSMMLSFLMMVASAVIAGWSDISSSGGLKQEAKEVGLMIPYIWMAANCFSTAFNSLVMRKKIRQFNFTDFDTVYYNNLIGVPILLVVSFFTEYSLYAPFYNKYFVENPEELFGLIVAVTFSGIFSFGISYCTGWCLRVTSSTTYSMAGALNKLPISILGMVLFDADVTLGGVLGVLLAFFAGVIYSYAKNLQAQQNITQPLPLHTYEKVNKSGDNLYDRTNIRDNSTILFEAENLFKKESADDIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZL5</accession>
    <name>A0AAD5TZL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000609">
        <property type="protein sequence ID" value="KAJ3214576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZL5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="441" mass="50113" checksum="16958E339DC52D0B" modified="2024-05-29" version="1">MSSSLTNDEVKMIPHIRELVNLLIEKLDQQSLNDSEVFLGSKRLKEDIVEIESFKPSSLNYRLRDINDGNFGEFDISKSQVFLSTKLIEELKFPVSILALKKINKNKSFPHSQQENFNPYYFFKDPALCADAVPFLSDCLHVLQAIDNLSNVSPTIISSGGLFTSLSKEIHNINSVSENSPEDDKMDIFDLDIKLEDANKAEDEIDLLDTRCFKLCLTHLMNPALCTFRAGNVTTCYNSSPLTSFESFTETRWISVYPKLKENNSNNVVQIDLENLINEKFKETSQSCSSPLCNVKSEPTTDDLASTDYINKKNFNSNNLHAKEVFIIKKLPKILFIHVNYSKQNINLQYNQIVIKKSLLILKELISNATGTEEKDFIDVSFNILSCCCINLTNLSCHSLIFSTNALSYNMCRVNENGSELIDGYNFAINERPIFFICEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZZ9</accession>
    <name>A0AAD5TZZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000959">
        <property type="protein sequence ID" value="KAJ3209117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="21382" checksum="3FA6999B0627E8E1" modified="2024-05-29" version="1" fragment="single">MKISNSTKPPNPSNSTKSCNQVSSCIHPNVELSKSNSKSCNQQTSLTHYTISNHDIYLLKLRLKHFIKEKRALQQLTIATKIDEDAATLASLSTTSNEYSSCDSSLASQSTDFSTEELNVDLNNFWNNGAFTKHNLNRKANSISCSLLSIKLKHAEETDINPTSPVDINHVIYANSSKDKSCKLRLSLLNSDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0K9</accession>
    <name>A0AAD5U0K9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000475">
        <property type="protein sequence ID" value="KAJ3216492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0K9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042232212" evidence="3">
        <location>
            <begin position="21"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="371" mass="42514" checksum="9CD99D3371794247" modified="2024-05-29" version="1">MHLFQLKSLFLLSLTIFTSANSIETLQKQGELSITISSHFLENDAQLNVTSANLKFTKTYEVTRKLDKNYTNNRYEGLAIDYKSSCIPNKMPELNYAKKYYYSNSIIFVNASDSFSCSFEMKLNNIKNLIPEYNFKAIGIYGFELIDQKDIDLIKIVATNGLSTEQSFLPSFLVENSVIGYIQHIIQHLPHYSNPATEDHDDDIASDQKNLELTPTDDKVNGVTDTKNDAGNTQQKPVVILNPPGIEAPWVVIAPLTKPLPQEIIIIITVGSIFAFGIIVALTLFVLYKKGKILKRRIREKERKRLLLHWDQSDIFLGNKKKYIKRVSRFDKYNIDLEKLELEKKRYMEANPNAKNVEIMDHVQAKLLVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0R6</accession>
    <name>A0AAD5U0R6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">LKB1</name>
        <name evidence="17" type="ORF">HK099_007920</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 19">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000813">
        <property type="protein sequence ID" value="KAJ3211799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0R6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF94">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="388"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3211799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="752" mass="86637" checksum="09045240BE53E67E" modified="2024-05-29" version="1">MDDGVRETETNRLKYIKNLSIATEYENISSQIKTAVDTIPPNDATIFTPSIDTPLTVTENVKFDEKKFDDFVFFDDDDEKERRSVKFSSSSVQAKNPNHPIEILGRTSESKKRSSVADVSLRSSETKRKSITDVHRRKSDIGKDIKQFIEKKHVFNILSDNSSGSLNTNCKNSVLLKNLSRKKKKKEEEKINPNNNNDLELFNDLKIHGKSKNSVESVFETDDYENEKLRFDFLNGDKNYEEDENEEEIENFDKINSLEAKKQQKSATEQEEEEDDNENQFFNFDRYCEIDDQNYENEDNFFENNSSNSLQKVSRSKKSLNHLNRDLGGSTQICAPPLSVAQQLGFADNQEYYEYLMLAQRHASTNFINSTDIIYSENAVRMKFIGPFLLGDMIGKGSFGKVKEGLCSQTLQRVAVKIINKKRVKKTPNGVENVLREIKLLNNLKHKNIVQLIDVYCKVDEETRGNTGIFNWFSSIEDEPISWKQDDGTEFECNVQVLKWYLVFEYCPCTLQNILEDEGSIDVTRNRDIKPGNILVTTDGIIKLSDFGIAEQFDRYNGSEMESTEFAGTHQFLPPEIVNGELKYYMLTGKFPFEFTKDGSILGLYELIIKCEYEIPDFLDSSCQSLIRGMLTKDEKKRFNLEQIKSHPWTLSSQNPEKQTPISLYPEQVNPVIQQQEISNQIDNNSDSKDKDLNNEDAEEEVAKNFDSCNFETTMIPYIEALYSAELEEDLKKNLTLEQLVMQLYPLEGINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0X2</accession>
    <name>A0AAD5U0X2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cysteine and histidine-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004222</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000293">
        <property type="protein sequence ID" value="KAJ3220532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0X2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1130.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007051">
        <property type="entry name" value="CHORD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039790">
        <property type="entry name" value="CHRD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983:SF3">
        <property type="entry name" value="CHPADIPLOID STATE MAINTENANCE PROTEIN CHPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04968">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51401">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CHORD" evidence="5">
        <location>
            <begin position="6"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="CHORD" evidence="5">
        <location>
            <begin position="153"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="223"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="39958" checksum="B5C2E90C5DD9B029" modified="2024-05-29" version="1">MTKVVCSNNGCGKPFSELENSITACQYHPGAPVFHEGSKGWSCCPKKVYDFDNFLKIAGCQVGKHHHDDKKPEFSAAPSNKVTGDKLEFKKHPKLASNAKDTPPTVEVYGKVPVLQEKLKDATLQPHKPEINKIKESELNDKKDAVISPGTKCKRPSCKVEYVNEKSKEGDCVFHNGEAVFHEGSKGWSCCSRKVLEFEEFLKIEGCQKGLHRFTDDGKEEEVTECRFDWYQTQSQVIVSVFAKKVDKTKTIIKFEKDKLDIKVKFLDGKNGVFKSLLCQVSLSNSVPLTGEIIPEESKFSVLSTKIELVLKKGNGISWPSLEPCENVTSWTTFGTVGGGGTVGGKEALIATDSPVHLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1M4</accession>
    <name>A0AAD5U1M4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000236">
        <property type="protein sequence ID" value="KAJ3221327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1M4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="300" mass="35136" checksum="B88B419C1C23D693" modified="2024-05-29" version="1">MPLSICLNKVVNFKVDFDNADFSVRSVYDIAQYYYGIGKNSTIGMCGSNTQNLVKNVVVQSVMTDLRSNALPMMAKYFYRTRKYLLGNSTNVEINYLITENSKLKFIFDDAIDKLDRISYEESSTPLKKYSFFNFTDTDPTPKNIFQHEKKESIIFCQKLLDKLDELDREIQFFLGKIDIPRSVDEVTECLIDSKKLISPLLLTHIRNVNEKIENNSRNFTFNQLILENKRINELLARSIEKIEVIPDGLNKEVLSDEDYNIKKDSFRLNRREAIVHLQALEKKTDEMSIKLREFKNQFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1N2</accession>
    <name>A0AAD5U1N2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005008</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000373">
        <property type="protein sequence ID" value="KAJ3218581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1N2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="89"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3218581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="29674" checksum="F974B0624605C2A7" modified="2024-05-29" version="1" fragment="single">MLLGYMISGTIYSIGQIISIVFVTVGVLVTTIASAESSVAVNAGDSEENFNFNKDWILGIGSLCSSVLISCFLGLYQQNTYAKYGSHWREGLQLNENKLINEEKRLEKTNKKLQNLYLKLDNIDKKKDSINNDVRRSKILKEIESLNADKHDINARILNLKMTEFLIKSGKLTPFSLLDEKFNHDISVKSDSEEEVKLTKNSISYELDSDFQLDIEGKLSDDDDNFVENDELEKTQSEENLIKDIRSLRILLLLMMEMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U262</accession>
    <name>A0AAD5U262_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDA2_2</name>
        <name evidence="6" type="ORF">HK099_006678</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000593">
        <property type="protein sequence ID" value="KAJ3214762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U262"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF133">
        <property type="entry name" value="CHITIN DEACETYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042152333" evidence="4">
        <location>
            <begin position="17"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="5">
        <location>
            <begin position="115"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="336"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3214762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="394" mass="42253" checksum="61BDF069B71D4605" modified="2024-05-29" version="1">MSKFIFAVVSSQLVLSQLSNILPPPAPLKYPSTDQSQMISGDLLTDPLITNALKYVESVVSPTILNIKVSTYQSGSTVTYNDNPANTCYWPNDLCVRSAETTDYKKDVFVCPNANDWGLTYDDGPSVDPTAGTSQLLDSLNVSNNLKATFFIVGSNAVQFPDVLKKMHENQHQLASHSWSHHPLTSLTNAQVVAEIKYTESVIYNATGIVPSYFRPPYGDIDDRIRGILSALGYHNILWTTTPPRDTQDASSDTSPAKAASIVQNVKDTFFPAQAGFISLQHDTNSFTVGVGISVLNEITKAGPTFPLKVQPVGQCQGITSAQWYQVAGSVVPPVNNSTTGATPGASTSTVSGTTESTTGSTITPGTTVNAKSSASKYNFGTVLFIISVIFTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U275</accession>
    <name>A0AAD5U275_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NADPH--hemoprotein reductase</fullName>
            <ecNumber evidence="8">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005666</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000451">
        <property type="protein sequence ID" value="KAJ3216952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U275"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000001">
        <property type="entry name" value="NADPH--cytochrome P450 reductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF17">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="9">
        <location>
            <begin position="65"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="10">
        <location>
            <begin position="339"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3216952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="807" mass="91719" checksum="7FC170962D3874FA" modified="2024-05-29" version="1">MSALLETTDIILIGLVSAVSVGYFVWKSKSSKPAGPIPVKTPIALPTKQSSFIKLAEEDDNPNQAILFFGSQTGTAEDLATRFAKDLTDTYGINTIVCDFEDYDMEELENWPLREDLEAHGKKWLACFFIATYGEGEPTDNAADFYEWVMNGQGKGPDEAKEDDHMTEGKVFSQLSFTAFGLGNKTYEHYNAMVRRLARRISKCGATLVTPFGEGDDDGSLEEDFLNWKDTALPAIAEYFGAKAVEKKDLPHTPLFIYKEISKITPQLESNIYYGEWSSSSPRRWKTLIPSADGTETFVSDVAPRYTEVRLKRPVRRSSTGGSNAERRNSGIEVIADMKHPYYSRMVLNKPLYSETENFDEFAFDLEHTLPESNEHYKAENGKIRINRQCYHIELDIEGTGIRYKTGDHIGIWAENDPTHVLNIARVLGVENKLDQFFELKPNPKNKTVGKLPFSLPCSIRTALTYYVDLRIALKQHHFEILSKYTKEEIDKEILWKLSIDREFFVNCVEKPQKTLYDILTEFPSVKVPLEVVLAEILPKNTLRYYSISSSSVRHPNKVSMTAVVVRYALANPAIQEISSNSSKKKVIIRQGLVTSYFQRLYNEKLLAVASNLESDKEVPIPKFHLPMYIRTSTFRLPADLTVPIIMVGPGTGVAPFRGFLWERFTAAEEGLDVGSTILFYGCRHPDLDWLYRGEMEDMMKRNLEFQNEDNSGKHFDLEIKTAFSRVPGKVKVYVQHLLKEEKQKVWDILSKKNGNFYVCGDAKNMAHAVNNTLTEIASEMENTDIEGGKNWLKDLKAAGRYSEDTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2F4</accession>
    <name>A0AAD5U2F4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000357">
        <property type="protein sequence ID" value="KAJ3218991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2F4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026171">
        <property type="entry name" value="FANCI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029310">
        <property type="entry name" value="FANCI_HD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029312">
        <property type="entry name" value="FANCI_HD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029308">
        <property type="entry name" value="FANCI_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029314">
        <property type="entry name" value="FANCI_S4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21818">
        <property type="entry name" value="BC025462 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21818:SF0">
        <property type="entry name" value="FANCONI ANEMIA GROUP I PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14679">
        <property type="entry name" value="FANCI_HD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14680">
        <property type="entry name" value="FANCI_HD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14675">
        <property type="entry name" value="FANCI_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14678">
        <property type="entry name" value="FANCI_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FANCI solenoid 1" evidence="2">
        <location>
            <begin position="63"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="FANCI helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="FANCI helical" evidence="5">
        <location>
            <begin position="434"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="FANCI solenoid 4" evidence="3">
        <location>
            <begin position="913"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1036" mass="119004" checksum="64D9020D01F2DBAE" modified="2024-05-29" version="1">MSEISYTELLNTTLTDDYLNKFSIENVSSFLLKSLETTNAQIIVKYLNSNSRIDLYIKMVYKFLAVTDLKGKEKFLDSIYAHLLSQFDNLKSETLVYLLDFSLNELKCAKLVNYKILGLLPKLIESLKYIDSVSIKKQNNSLVETMSGVEYRDNIIERATTLNWENTQLIINMAISLVEIDLNEGQRKFLATKLIRLLKLVELEDVPTLAYQILLLSKKGNKSAILLGISKFFENEAKTDSQQSILKSQGIVLTHITFAIKQDFELGNEFLKICKKETLSTFKLSLLLSMATIYRFEYAVFEYLKSFVFVGFCDEQRKLKIPWIRKHKNLVYESLEDILSAVIVQNTSREDDPTELTQNVGIRALRVTFNNHKFIQPIIIEQVLARIESKTVGAAKAIYLTNEKRQIALAGYLELLSSRNYLRPTNSQFLNRVGSFSSEILDILKNCFNDQCVVKKELYGGLAEAALVRPPLAEYFLTYIGDNDLIKVDACLTNTNGGEPKIHEPMYHALKCICDCLLMVKHSDSEILINYRERLDSIIAKHCNASINDFELDKDGDYSSSGNIGKRNQYRVIVLIGIYIVFMEYSFKKSEILILGKKVNYEIFSAAYHKMLALEKLVKEKEKISGFSNSFKKFDFETCLQFIEQVFGADQVVEELAEELICRFVSSSLLESLQLTIASNKPIANLNPYIKLGTLLYSKFIEAARENGLSTTQIGKKEGKQFCDAKTYREAGFLIDCIQNISNVVDDQEICKLMQNWLIDFLKKRDIKDLGLAKKSVQLLIVLENVNRAGDVSKVVLNSIIYLLDDIEWCIMQISKSRKAKDNRFVWDEFEAIICKHLEPVINVMSDFEGYGVIVLILNYLFSRIVFDGFVFELRMKAIDKCFKVLSNLVKQNTLILTLKLLSLPHGNDIEETEDLEKKMKLGGKKRKIKDAQLKATKESKFVPKIVFLVENFERHLIQLSTKSKVNLTRYIKVCFILLANRITNSNCFYKRSTARDFRIRLDRIEENEDDEVKVQETEKENLSSINENVKKGKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2M0</accession>
    <name>A0AAD5U2M0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000197">
        <property type="protein sequence ID" value="KAJ3222001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2M0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="1018"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="896"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="900"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1246" mass="141983" checksum="4528C738B2ACE935" modified="2024-05-29" version="1">MSHRRVQVLNIKTKNGTENQCKRKDVKIVEEKRQLTRRPSDHAMPPILGNDFRLILNHWDNLKNNKDDNTKKRTFTTSKHLPYILPQQPNLNKNQIDEIMNNSVSANVDCQQNFTEYQCGVNVKDFCEPLSHKDSNKDIQYLAKFKNENLVDYNLFNQVYDKFNFQPQLNMNEISNLKSGVLKHLTKNFSYIHDSPRSHDTDSVISGLVTTKFITSTAKSIPILNTKSTNVQQNKMNDELVIAAAESYEAEGSGGDVYSKKQCIEGKKVFTDPANIKDLNVEEVFREVNEEHGKLTNTSGFLFKNQSNILVTMDNKFEANKEIIDPHKPNMIVVSQPEKLRWGASKKVSQAIDLELEYHYHRRARTEEFPVTSNEQTGKLFKINNLRLYSDHKRAKTEECQGSNSKSFLVNAANKSLSEVEVSTGSKVKEMNKLKKRYHFEKPDEPDLNLTTVNPKINENLISTNNTYKILSETENNTDNQNSSDYIYTACSENQNFNEYQNLVNEIHTKVPENRNFNENQYSPIFSGIKITESKENHNKNSKSAKVEENKNFAEHQFLLSANGSNFFDNGNFNKNLVSTTSSNTIFPEKEILTKIVSKINSIENTKVNDESDFFDPIKSRNSNSKENSVLGYNTMVSRNTKESDAVSSNYMLKDIETTLSINENSDSVTSFVDFTKLSESPVPEEYTDFNNFNSIINSENSFNINAAETAINDAENVVLASRASQIVLTNTHIPQKIDKNSFCIPVEAYNKEEHLPGTVITETYMSGVDVFADENPNNREKHILNFSSLIDIPQAPKPLIHYQTHPLTSTQAETAREKRMKFLKVKEKEKKHRQNTNTSKIKSTSKNVFDNGQSYLLAKILKKNEKSSKVGSKNFDPSSEKDIKEFQKIYSMLPDVENNSDSKSSKLPLSKHNSQQKVSVWRPGGMGNQKLEEFMRNRQRAKLIGKSSFLKKSVAEDEFGFPDINGLRENFIALDIREGQLLENQRNRIIRSSDFLDTEVEELNPQQILDMVWRGYKYLNSLEAPVLESQTVHNILSLAACYNYNMDDCTVEIKKVVAKLPRQSFVVLKAIIAHFKRLSAMSNTDITKGLGSLFGPILLPRLNFKPKNISVIKIETENCSMNSLENLNSLSTKQSYSSLSEKSVHLNSNSVLSEIPGIEKFPLSRVRSPLPLLVRDSLTTNRSQKILLTTVENITEIDTQFLTKRQVFAELYLTELALCSSATCLELMIKSFSSTFAFNTYNTVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3M0</accession>
    <name>A0AAD5U3M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001236</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000133">
        <property type="protein sequence ID" value="KAJ3223360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3M0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_bL17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_bL17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="Prokaryotic ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="586" mass="66982" checksum="D954D8E78E9CEA2E" modified="2024-05-29" version="1">MTPKHRKNLIRNQISTLIQRERLETTVAKAKYVQYYANEIIDLAKSGTESDLNIVSQFISQPEKHFPKLITEIAPRYQNTSDYTHIILNGTNGGKKNADHHPKAILELIGSKNSVKLAFAKKFKNDIETRLENVENTLYSKKKELLVDPVTGNIKEFSFFTEKDILRTEKLRLLREERKYTRILKEFTKNLESHKQQSIDLLKFKDRYEEINKERSEKSIAAAVVDNGKPIASVKPFNRNAKSISNQAEVEEKKPAESTKVEDKPSRGFKFLKRPKWFRGSIIFDDIFRFFDSPTLTYYTNFFNSFIWNSLMVFGVLFYQLLTIQRFSMIIQKIKPYPKFIDAVLAFIVIGLNLVPLGVGWTRQQCKKDYNFGPKSSLCSTPAFSSSVVQNQFWTIQAVGTPVFESILGLIVLITLLRMKKISDIFNNCQNSSTEVAQKLKKIQKGIKIFLTVWMILVWAAGLLNCINNYINSVSQFSFFLQTCQFTMYFEFHKKITQLAQISMGIVPELKASALESGVNKIKLKISRKLSGFEAEGEDGMENELKSALASDMGLMKSTCSEGDAIDNQCQSNISKTSPNAVDDNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U408</accession>
    <name>A0AAD5U408_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_001068</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000128">
        <property type="protein sequence ID" value="KAJ3223485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U408"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000274">
        <property type="entry name" value="ras-related protein RABA5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="324"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3223485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="375" mass="42450" checksum="4F0E42E2DB09F462" modified="2024-05-29" version="1">MDSSDYDFLFKVVLCGDSGVGKTNLHLRFQGKEFKPDFKSTVGVDFATKTLKVDGKTLKTQIWDSSGQERFRSVSHAYYRGAVGALLVYDISKKNSFESLKTWLKDIKNYAEPNITCIIIGNKCDLSDIREVSTEEGKEFAVECGFSFVETSALDNTNVDKAFEQILTQIYRVAASKALEKASANLQSPEISRGENVILSPISNENDTGSSCAFRNSLQDVSGDSIYQSCNGLDETHLTSQCYVHHHNLVEDLNLAIQLDKELNFHNLVEEGRFNDENLDVDENLAILLTFQFLEEDSQNRFFTNNNILTTETISRLERTKKECCICMEELKFDDMENEVRALRCIHVFHSSCIDNWITSGDNHNCPICRLTINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U409</accession>
    <name>A0AAD5U409_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000405">
        <property type="protein sequence ID" value="KAJ3217888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U409"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="119"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="469" mass="52282" checksum="B136AFD43A0A1E6F" modified="2024-05-29" version="1">MILKSSATSAVQNSPSPTNSSYNEIINSLPSPPVSLTEFKSTSYDCDSTTEQFKSNKRASIQYLYKCNRRASTISSSSVGGKSFKSALSDTNKSITSNVSIPKMKTMFRRVSLFSSPTDEVSNLSIRTPEASNDDETNSGSTTLPSSINYNLEKEESILDHQPKSHPKNQRSVTFNNTTTVNEKSQTLIESENINTSNTKNKKKKKSSLTLEFRKLAGKFSSKQCNYLGLKFEEEKDYASAFKWYKNGAEADNPAAQYNAARLLSKGLGCATDLMQSAKLYALSAEKGDSNSMNNLACLYKKGKGVEKDLSKAFELYKKSSDLGNATGSFNLGYFYEKVRIGVLPFEFLFLKGIEKSVDFEKAIEYYAVAANQGHDHAQVNLACLYVQGRGCEVNYDFALRLFKKAAEQKNCHAFFNLGYMLQKELGLGENQNTAEAKKFFRLALKYGDERARVILKEMEIEDDIVLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U419</accession>
    <name>A0AAD5U419_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial potassium channel ATP-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">ATP-binding cassette sub-family B member 8, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Mitochondrial sulfonylurea-receptor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ABCB8</name>
        <name evidence="21" type="ORF">HK099_005288</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000402">
        <property type="protein sequence ID" value="KAJ3217970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000218">
        <property type="entry name" value="Multidrug ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF17">
        <property type="entry name" value="MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="14 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0630">Potassium</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="543"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="693"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="774"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="20">
        <location>
            <begin position="554"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="19">
        <location>
            <begin position="840"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="1427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00040439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00041416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3217970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1427" mass="160911" checksum="7F56A934FCE0C709" modified="2024-05-29" version="1" fragment="single">SFSCNMKGKHITTTLDANLAEGGKKVDSAVSIPIFNKEQLHQSTSNNSNSNSRKFDDLVKIIIHSIRGKEKLVEKIKLSLSKVVLERKKQDSVNGFVSGFIGAAVSLSFLNSREMKKSISQQMAVRAGQAIYNSLKAKSLFSFPHGDSMLFMLSCASIMYGYIMAPQTIPREYYSWMIKTAKIPKNVLEYNRDTVRNIKDSKNMNVLSERAISLIKQYGKRNTTNTIEIASKNFQVNPNIVSCAVLHPTHSSCTKYNASLSKKVFCDIFPVYASLNIVPLVIFRGKSFVKSPVASLVRAVKSSTQSSFFLAVFVVVYMSLICLQRKLILGNTVKNISKNFFLSDNKLWYYLFGIICSSSIFLEKKGRRSELAMYVLPKGVASLYLVLLNRGYLIKVKHFDTILHSLAMGTIMSFYQTEPEAISSLLYKIMRNVNQYQLKKVNQKFFNSRKIIATALFVPAAAFISYEYYKKGNLFFTEVLENLKFLGDDKEEPSNTENIDLLAVEKAENKAFIENNDSKDQELEIPTKVLVKEIWRHLSPHKLLLFSIVTITSASALINIATPMLIGEIVTVVQTTLTAASPTERDFSGLNSAAIKLMGLFASQGLLTFIDIALVSLLKEKINKSLKLELYESLLRQDISFFDKNMQGQVTNRLTQDVSEFKSVFGLVITQGLKCFTQVVGSAIHLFKVSSKLSFALISTMPLLYVFLNFYGMYLRKLSRLARIGDGKANGLAGEAISQIRTVRAFANEDKELKKYAEATSESTNTNSHLGMHVGLFQGITNTTIGGMILIILYYGGKLVSRNEMVIFSASRIFEYIKLKEKISLTNGIEIDKSQFKGKIEFKNVNFVYPTRPNQLILKDFNLTLPVGSVCGQSGSGKSTIGQLLERFYEPYQGEILIDGIPIKNINPSWLRKNIGYINQEPTLFATSILENIRYGNENSSEIEVIEAAKKANAHNFIQNFPDGYQTMCGERGATLSGGQKQRIGIARAILKDPTILILDEATSALDSQSEKIVQEALDYLMRGRTVLVIAHRLSTIQNADLIVVMSGHGMEHRATGNILESGNLLNKIFPNCKQFDLTVGTHTQLMKKKGAYFDLINYLSIFLEESNCEKLECLALSIETKAFESSFSMEMYLSGMEMLLKQVIELNKPIQRTCNYVRHVENYFNHYHSVNEECKRATQVQYQRNLLCHIADLIKEFNLNEHAFPDYERLKFFLIDSEGAVEQPHNPEKVFVEKNTESSNRQSNKSCAEKRFCGYRFPMEDFVEDTIECSLDDGKNEPVEKGIKGKKKTQLENYRNNDVAKLKGESFAEFSKDVGVKKCKKGKEIEKFPVENDQNNYDPIEAMSENIEALQQTISSLNNMCATFDATVNLIYKAKNQNHDNKKTYNTLSQDESEKIVDETCDFVTVGDLQESPKECSRQPVEVRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4I0</accession>
    <name>A0AAD5U4I0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">POR1_1</name>
        <name evidence="11" type="ORF">HK099_000391</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic mitochondrial porin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000109">
        <property type="protein sequence ID" value="KAJ3224014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4I0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07306">
        <property type="entry name" value="Porin3_VDAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.10:FF:000012">
        <property type="entry name" value="Voltage-dependent anion-selective channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00185">
        <property type="entry name" value="EUKARYTPORIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-0626">Porin</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3224014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="285" mass="30688" checksum="4A35C6F7DF770F40" modified="2024-05-29" version="1">MSFVPPNFADVSKLSNDLFNKDFPIGSTKLDLKTYASNGVNFTAVGTKDNKSGQITSELQTKFTDKQRGLILTESWNTANVLGTTIEVADTLAKGLKLTLNGQLHPAVGKKSAKAGFEFKQANIFTRAYVDLFKGPTIATDAVVGNADVLFGADVNYDVTDAKVNKFNTIVAHTTRDYTISAGATNMFGLFSFSYFHRVQPGLEAGARAHWNKSTDSAVSLEVGAKYALDLDSFVKAKINNIGVLGLGYSQKLRPGVKVGFGGSFDTTRLNENAHKVGLSFTFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4I4</accession>
    <name>A0AAD5U4I4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000175">
        <property type="protein sequence ID" value="KAJ3222441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4I4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007914">
        <property type="entry name" value="UPF0193"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28348">
        <property type="entry name" value="UPF0193 PROTEIN EVG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28348:SF1">
        <property type="entry name" value="UPF0193 PROTEIN EVG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05250">
        <property type="entry name" value="UPF0193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="286" mass="33560" checksum="C57F16D195CBB6B3" modified="2024-05-29" version="1">MSIPAIPSFASSRQFKLNQNIQNTSSKRYQFDDTNPTAEIKFPQLAELKSIKHINQRTFAVRNRPSFNNKEKSNEKNYANKNESTADIKSKNGLSSDVKLLLKSMMGTSKLTHRQQLLLDEFVSEKSTLPISKLDIEKKKKISLLQNNLQTFRLTIDDIKRNNKPHLRSLETIKNSGCYNPDINYRPFQQGKNRELQIEEFAKKMSGLENIVISQKEKKQNEKHINEYTVEEEEEIDEITMLKSEILERKNWLEEMKQLGREKEFKSKINQEIESRMSRLKLLHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4L4</accession>
    <name>A0AAD5U4L4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinesin-like protein kif27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KIF27_1</name>
        <name evidence="10" type="ORF">HK099_002257</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000173">
        <property type="protein sequence ID" value="KAJ3222503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4L4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF11">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="319"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="437" mass="48743" checksum="852088C5618C2D18" modified="2024-05-29" version="1" fragment="single">LNWISVVKKHQSLNKVMSLFRKLSKSFNIKIKPLSLNLENSNSNQINKNETAKEEVDIKKATSLEFVLHVSQANNVIESRSKVNDVEQSSLIQVNSHEQLLNFSETPYLLSSSEEVEDPVDASAGELHIDQLTTFAAFGVNLPSLMNQKTGERRASSSSAFALPTSPVVVSNPQCRRHSMVEKTNLNKLSTSIKVGVELPSIKTKPSLNSDTFLVNINSSSKRYSSSTISQPRKSILKNRPGSYEKSTVIDQDILVDYGGDVKEHLITNSKNKHSIMSTLAGASLKENEVLDDDIKKSLALEMPFFEESLKKCMTLAIYLSGEMIIHKHDIGYEMYFLSKGKVEILSSDGQTQYGIINAGSFFGEMGVLFDIPRTASVRALETCYCMVLTREKLTSVISRFPTLETRFRAVVSARMYEVQGKRARSKRVQINLPSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U504</accession>
    <name>A0AAD5U504_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DHX29</name>
        <name evidence="10" type="ORF">HK099_008162</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000087">
        <property type="protein sequence ID" value="KAJ3224617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U504"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000500">
        <property type="entry name" value="ATP-dependent RNA helicase DHX29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF145">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0347">Helicase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1152"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="domain" description="RWD" evidence="7">
        <location>
            <begin position="8"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="674"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="946"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1176" mass="134836" checksum="B5AE010FEA0A52E0" modified="2024-05-29" version="1">MDNPIWNSEVEVLQSIYGNECVKQQSNNSIIIKLFLAQGLVELGVEVDQFYPVAIPKYNVKTYWPVAAADHGGFCQLEYSALKTINEKFLEIHSTACGEVIIFEWVEFLSKHLEAISPNQADTSDCVIIEAACSEEDNEVLNTRINDSSSYTKHTKKKPKSKLKSKKANNRPVAAFSTVNVKKAEEVLEEPKKSDKQIADVDLNLLLESDNVNNVVLVKEDFDRIALHKIDDEFKKELEKKKKLGADLVKLKISDKVEFSIIELIREQFKSNWSSVRPVDLNLLKDSFNTAPNSNQTNLFKTLNLNYLRFEKVGFTRDVIENIMWESWGTSFSDSLDWESENENDDSVNLQYAKLKIEEDNLKIKGGKNGRKLKQLKEKLELLTSNKDFNVKVANEEFQKLTKPFIDRTKKKSKRPEWEIEVKEKDEIEMGDFFEKEEANVSMTLQPSKCKTVVIKNFAIASSWTGKSPKQFLTDWLSKNAKGCKLAFSSLPTNAGHRIKAYLKGNIKDFENKVAIMEESEIVMTLKEAENYASTKLLYLLLPNLPIYRNLPPPFRELWLDLVKVDENLEIDEKEKLNSQRLSFLTKLYNFIQPKIQDKLKLSQNFGSNKENFEHVEREYSKKGGKLERRNEKFNSTFANCKSIFEMNKLNRFYKQLLFKRQTLPVFSQREKIIKACSENTFVIISGETGSGKSTQVPQFLLENSFEILKEANLICTQPRRISAISIASRVSEEMGEREIGMDKSLIGYSIRLESKISETTRLTFCTTGILLRRMEIDPYLEKITHVIVDEVHERSLESDFLLLLLKKLVKVRNDLTVVLMSATADSQKFYEYFFDAHTPCICVDVPGRTFPVTTMYLEDAIQDTSYLLEEYSEYAVYDNRKISTAKLNVTSKGGKSIQTTVQWSGSDSDDKDDFFASDDFSSNKYNINTINTLKRIDISKINLELIERLIFKLHVEGPVDMNGDRGSILVFLPGYGEIKRLYDVIASNADRNNMTVLPLHSSLNSNQQALVFKPSHSGFRKVILSTNIAETGVTIPDVTYVIDTVKSREVSYDIKRHVTKLSEVFISKANCLQRRGRAGRVREGICYHLVPSKFFFMSLLPQRQPEIMRLPLEELCLRIRAIGYKLPFSQFLSDALDIPPLENVARSVDELMSVGAMVLFMVVIFNFVFRMNLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U519</accession>
    <name>A0AAD5U519_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS26_1</name>
        <name evidence="5" type="ORF">HK099_003435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000225">
        <property type="protein sequence ID" value="KAJ3221523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U519"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="61" mass="7085" checksum="412A422B5B27613A" modified="2024-05-29" version="1">MVEHAAAGDISEASVFQEYAIPKLYIKMHYCNSCAVHSHVIRCRSRETRRNRAPPPRFRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U529</accession>
    <name>A0AAD5U529_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000089">
        <property type="protein sequence ID" value="KAJ3224566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U529"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="236" mass="26659" checksum="77056C124B1B8317" modified="2024-05-29" version="1">MKLADLNTKGGLNIRLNKVLIMENFPQNSDDSKSSSSTIKAQKRDMGDMGMGIDPYGLTWSVLEQELDCNHNYEVLFEYQGVGETIVDVTFDIINPFTFIFKLIVLRNATTVIDSKVENIEGELQKVQNNPLQKIQEGNENNQSSADQTKAKTSSAMLNLFFIFFLTVLALFFFIFSKRKIVKKSRSRSNSDGLLTFDKFVGETDTNGVSGDNMEMYGVNKDEFTFINDDDDSDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5C2</accession>
    <name>A0AAD5U5C2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000205">
        <property type="protein sequence ID" value="KAJ3221855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5C2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="141" mass="15582" checksum="71A96D2A0AB163B6" modified="2024-05-29" version="1">MVAILKNQLKETFTYHALVSLYVLFITYVFSIFVIDIIKGIEEVEVVAENGSMDSARESELINNEENVGGLNTSNATEGETHQLKNKGKTAEVGPSIAVYPVAVEANKTPLPQFGSTYTAEKLEKHFDEDYSFTSKVLPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5T2</accession>
    <name>A0AAD5U5T2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transforming growth factor beta regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TBRG1</name>
        <name evidence="4" type="ORF">HK099_002276</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5T2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003889">
        <property type="entry name" value="FYrich_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003888">
        <property type="entry name" value="FYrich_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040092">
        <property type="entry name" value="TBRG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22715">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR BETA REGULATED GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22715:SF0">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR BETA REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05965">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05964">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00541">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51543">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51542">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="7"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="309" mass="35968" checksum="ED45738A6768A9C8" modified="2024-05-29" version="1">MIYEIKYQETKLKYTELNSEYRDIKSQYNKAEQKIKRLETEKEKLLDLILHLKPSLTVLTDDCITDTDIQELSCTSRKETVVIPPKKLVESNNTLIKVTNSNEQDEESEIDLDGVDEVEPVVDGKLRKRKFKKRDTRSSAKKLKLLKMDEENNLILPFTIKKNGSEVTILNIGTIIHDRDSFHTPRFIWPANFHSQKLYHSFTNPDQKCIYDMFILDEGENPIFQIVVNDEGVEPRIFRATSASGVWKKALQELMERKIPNAKTTVSGPDFFGISDLGVINYIQELPDAKRLKKYIRQKWITENEEKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5X7</accession>
    <name>A0AAD5U5X7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-glucuronosyltransferase 1-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">UGT1A1</name>
        <name evidence="3" type="ORF">HK099_008699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000099">
        <property type="protein sequence ID" value="KAJ3224243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5X7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="557" mass="63877" checksum="F8B6F92311B12E37" modified="2024-05-29" version="1">MKFLLISVPTPGHVNPLLSLAIELLEKNHTVEFMVSEIYIEKLKEKNIKNLILTSNGNVGFDQTFFSKMTNSTQESLFQLMFTVKNFALPRILSYLDAIVDILSLKFKVEKYDSLIVDFILAPVTSVADIFNVPVIIYNPGVTPYGLYDPDAFSFPSWSYYLTPEMDFYSRLKNFVFKSFTEVIIFNLLNYKINDIQKKVGLNKTTRLEFFRKKLVISTSLPGLDFPLPRFPKMQLTGPCLNLKSNLRLSHELTAWLDDPVELPVVYVSFGSIGASPKHITPMLNSVFQSFQKQVRFLFATLALSQVQEVEKYKWSTNVRLEMNGVPQLNVLEHKSHCGGNSMFESMHFGKPILCIPLGADQYTLANRVIYVEVGSAILTSEYDFENKLENLIKLILKNAKYKKNAEDLGEWIRIQNSCSMQVNLIEASGKNLTKFLFPKQIQPNTQFFNFDLQFDVNALKAKKNSLKVKECIMSDLSSEIVKHNSNAVNFVNNFKEIGEFSDYEDNFSKFTSGFSESVKFLDDSLNNLKEKFEVTIESENFYKEISERIEKIPIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U627</accession>
    <name>A0AAD5U627_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000095">
        <property type="protein sequence ID" value="KAJ3224362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U627"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332:SF1">
        <property type="entry name" value="ELMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="199" mass="23471" checksum="A1DECD4EBD5EEB2F" modified="2024-05-29" version="1">MESEEESQWNINNIPKRIMILNYLKNVSSTKTNWLGTMKIPFSELSMCYEAEKFKKRTSQLFLLGTSIGLLLRIKDSNEFAKSLVILMQEFEQETKEKNSRQRIFSRSKRSSTSDLSLMEKENYVYLQPIKHVYFVITFSTFCEILSQTYEKLLKTSDSQLIFDLSKFDARIKKIVNVMIKEIDAIARKLIKEELYTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U670</accession>
    <name>A0AAD5U670_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U670"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14361">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052617">
        <property type="entry name" value="Huntingtin-int_K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038922">
        <property type="entry name" value="HYPK_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184:SF2">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nascent polypeptide-associated complex subunit alpha-like UBA" evidence="2">
        <location>
            <begin position="106"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="16950" checksum="B527DCF8C43C0019" modified="2024-05-29" version="1">MSRRNKNKNNKKEEKKEENKDVKVEEVIEDKGETANDIDKEEENEKGQRAEANKDLGHMYQEKESKADIDETKLYKAMTSVIKLHTDLSKTRTKATSQSQLESSKIVINKEDVELLVKELNLSKVTAEKSLKDNNGDLVLTMKTLIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6C6</accession>
    <name>A0AAD5U6C6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6C6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="157" mass="17683" checksum="B7460989D2AE9DDF" modified="2024-05-29" version="1">MEYFNKVKEHFTTTKVVFAVSTSSLILTILNIRRQRSKVTFNLQHSLEHPKVAAYLFAGRAFGHATLLTFFGSTTIASGAMLSMGINDMKDASTILVRYKSYFPVSKQQTLEEEKRDTDEFFKELENTDGEEDFANSKAHAGIKNVVLKSLGPLRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6L6</accession>
    <name>A0AAD5U6L6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000037">
        <property type="protein sequence ID" value="KAJ3226397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6L6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="710" mass="80933" checksum="680B3350DA2C98EF" modified="2024-05-29" version="1">MNSLLSLIEVAPKRNSLINQFFTINDPTLIYNNEEVLLNSLKLIKCSTNKFSVRYSLKLMFKVLALNGFKTFNVKPLEVLRSVISCLKSVWLHNDFECIHLTSDLLIKLATQVKLEESEVEHLVESLGSLLTAESEFGLNLTHHLLTVIFHLIDINQFAYKLAPLSVQLCNLLNNPEINTENAVKVATILQHIVDRSKQSFLTTTSFADIFKFLKNSYSKNSESFAFLLLFLVLNKAMTLHTDVFNKVGGIKLMIPYLLCKRKDVLREVVCIILSSVKSTVELNEKVMEKLVNNLNLLKNLLREKLDTTMSDDGFIKLTVEKILRFLVKPTKNFNNSVSAKDIKVVDLRLDAKLLAMSYNVPDNVVTYLPKDSNMAEHCLQVQLPADDPFSDLKEIIECTSGCSSNYKRLVNLDVLKLKIKNFNGVIPTDHLLSLAEFLFTLLSDADEVIIAALQILSLLIQSDLFRKLVYEKRGLRYLMELLDLYNFDILEECLKIVSLFSKEGSGPKIVAEAKTAVINSVWESLIEQWKADYDITGCMFKISDIGKQKKKKTAKNSQEIKVTVWNTDYLMVKQFGFLETHPTVDCPKCKKLNLKTFNANVSVQNKRGSVMIEVLLPSYVVAARYSFLKISGQMSDKDFYQKHIQEIDTRDEKIKNYNLLLQQLKDTEDENVLKLKNDFETSVSESNSDNDQLFPLNSVKELNSEGEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Y4</accession>
    <name>A0AAD5U6Y4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">SRP54</name>
        <name evidence="17" type="ORF">HK099_004505</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes. SRP54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101. Both, SRP54 and SRP101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon). After signal sequence transfer, SRP54 and SRP101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: srp72, srp68, srp54, sec65, srp21 and srp14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The M domain binds the 7SL RNA and the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit srp101. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Y4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006616">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000022">
        <property type="entry name" value="Signal recognition particle 54 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP54 helical bundle" evidence="16">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="74"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="15">
        <location>
            <begin position="75"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3226625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="524" mass="57775" checksum="EC2014D6AFE3B467" modified="2024-05-29" version="1">MLDEVIKDIQRALFESDVNARLVKKLTENIKKTCKLDEIPSGVNKKKLIQKTIFDELIKMVDPGTEPWKPIKGKVNIVMFVGLQGSGKTTTCTKLAFYYQRKGFKVCLVCTDTFRAGAFDQLKQNATRAKIPFYGSYSETDPVQLAIDGVDKFKSEGFDLIIVDTSGRHKQEAELFAEMKQISDVVQPTNSIFVMDGTIGQAADGQAKAFKSTVDIGSIIITKMDGHAKGGGAISAVAATGSNIMYITFYLPKFNLLFSFIGTGEHIHDLEPFTPKSFIGKMMGMGDISGLIETVKDLNLDQNKNLMENLEKGKFTLRDMREQFQTIQSIGPLSKVMQMMPGIPPEMAQMGDKEGTKKIKTFMCIIDSMTEKELDSDGKLFIQQPTRIHRIAKGSGGTVMDIEEMLKQHKMFAEMVKNLGGAKGMLNQQGKGRDQKNMQMHPNQMKQMQNMQQSMQKMLPPGMMEQMGGMGGMQEMMRSMMGGGGLEGMMEKMGMGGMDLSSLMGGMGASGAGKKAGSSRVKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7G9</accession>
    <name>A0AAD5U7G9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7G9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="107" mass="12977" checksum="0D013E6C9470B85B" modified="2024-05-29" version="1">MKTQTGLKEALNYMPLLQLGFWFNTDNLLSHIIDEHWDECKNCRINFEYAQENFEHLVKRHSQWYEENVNLDVDELNSIIDELLSDEEDEDEEDEDEEDLDEDEDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7L7</accession>
    <name>A0AAD5U7L7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2 10">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HOG1</name>
        <name evidence="12" type="ORF">HK099_001848</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2 10"/>
    <dbReference type="EMBL" id="JADGJW010000157">
        <property type="protein sequence ID" value="KAJ3222831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7L7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000049">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="7"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="29508" checksum="81B7805B65B2E834" modified="2024-05-29" version="1">MIPSNRYTDVLPIGMGSFGLVCSAKDTLKQISVAIKKISKPFSNPVLAKRTFRELSLLKLLQHQNIISLNDVFMSPQDDIYFVSDLLGTDLHRLLSTTRLESQYIQYFIFQILSGLKYVHAAGVIHRDLKPSNILVNENCDLKICDFGLARATELQMTGYVATRYYRAPEIMLTWQHYDNKVDMWSVGCIFAEMLEGKVLFPGTDHVNQFSIITELLGTPSDEVIKSICSENTSRFVQSLPKREKVSFKERFPNSDALGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7P5</accession>
    <name>A0AAD5U7P5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">IQCH-like ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056855">
        <property type="entry name" value="ATP-grasp_IQCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038752">
        <property type="entry name" value="IQCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14465">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14465:SF0">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24923">
        <property type="entry name" value="ATP-grasp_IQCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IQCH-like ATP-grasp" evidence="1">
        <location>
            <begin position="697"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1204" mass="140479" checksum="34D8002C1333ADA9" modified="2024-05-29" version="1">MQISLPTIKNDGILNQSSLNSNSEAYSYPTITADPQKSKKNSFYNNKEFFNEPSHNYRLFQFYSKSSNTEDTDKNFFQRLDDVNAGIDANNIKRQVTHHNDFFIERITDRDLNLNNFNENNIHRTIDYRNIGHWFHQKDSQLHDLREMKDVYQNIDSIFGTIKDEIINDGILPLINRGKIPDYVDLNGIMTEKLNLTNQDYVLKPTTIINLKKLNFYFEVKEKNAKKTNAETNKNRYQLYQDGLNESFFSKIEFDLKNKKLNLKLSQYQNLKPPNFVTLKLKKKYISKCHSNVCSEAELNLRNHSREEYEYILIIAFKGVIQITPSYNYFLKLNMEYFTEISAIFFELSQYLIIYSVEFAEIRCDAILRWAKSLDSINLKKIDFKECIFNEIERYEQIYLKKYLKYKEEIKENFKKFTEGKRVIIQFDYTPQTFNDDIVPDINFGRCLFLQDPLVDLIIVTPSLIEDKREFYKEIIKNNNLENYMERIHFVAPETWKNYKLPETLDSTSAMRLTHMLLTSTRALKWIKNFIKGKEAVIWVDQITKTEVAVSGILGIPILGPTIFDYYSNNKKSSVKKFFTDAGVNFAPGMVINRDSGANLSIQIYNLVQQNKEMCLWNICNEDNTINDRDLYEGRTLLSHFNLDIIVPNEYGTDLKEDSKIALFKILSECGFFEGNLFSPLRKNFLYLQGVPKLLGDEMNFIEIVLMVDSKGGFEILLTLEKLKDKKFKNVGKIAPQSKFNNEDLQVIIKKIANTCPIYGIVGLISLDLVTWTDKNDYFQYHFTELNMRPTANVIRIFSTMITTGLRYEMNCNEFAFYKDDIPTKIEHLRSVQHSSLIQARFDFESKLLGYIKPRESRIIYYSENQSHSHIKIISRKTLFALNKLNSVKFDLWARLGSFVPFSDIVCDTSIPVVCIGENIKSALERYIKDLVKIYRQVDVSYVESTSNFKHLCERVMQYISDYIGTVVPITTNLESINDFEDYAAQYYTVARSQPKSARKLSSHPQDKNVMLTHTTTNILNTLIASQLVASIDPTFRRPAISPPYSRPQKQKHVTDDNASKRTLEIMKEIEEKVTDEESKKPKEKNALMSWREELDIWQVRSNHADKMKHLFEKLETMSKRRSALVENIEDVLKKAEVMITTQREKRKELFPTDIQEIASTPVKSKRSKSEKLGHIDNAIALALLSEKKERVKTALGDMMTELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7T0</accession>
    <name>A0AAD5U7T0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PPP2R3B</name>
        <name evidence="4" type="ORF">HK099_001426</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000014">
        <property type="protein sequence ID" value="KAJ3227577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7T0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095:SF0">
        <property type="entry name" value="MIP22305P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095">
        <property type="entry name" value="PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="147"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="350" mass="42164" checksum="A83332D3C9E410F6" modified="2024-05-29" version="1">MLLPVETVILRTFFEKKNSQNKRMTLLEFKKSSFLPSIELLSNLKEDINLTRSIFSYKHYYVMYCRFWDLDLNHDMKINFQDFQYFNNSSLTRVMCNKIVKNFRSERGFRNRKVAFQDKSKIEAEVDDEFLTFGEFCFFLLCNEDKKKDTSIEFWFRCLDTDADGILSLYELKNFWEEQYERMLCINFPDPWLFDDFICVLIDLIKPNDPFKITILDLKKCKKNTELFLDMIFDIRKYEHHIKRNHPEFRDQDDIYICNSGSNIKIALDGWDKYAEKSYDEMMRVESRRRQTSNNSFSSNNSYNSSQEQNDYNLDNMEWSSNLYNGGWDDNEDHQHNSNEVVQDFTSTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7U6</accession>
    <name>A0AAD5U7U6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7U6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875:SF2">
        <property type="entry name" value="ACR183CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875">
        <property type="entry name" value="OS09G0542200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="1">
        <location>
            <begin position="17"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="192" mass="22122" checksum="0BF20CA83DE2C9D1" modified="2024-05-29" version="1">MSLLFNESGNSTLTLPKHTVEYFLDYACPYSAKLFATFLSFQRSNFVKDKNVNFIFRHQVQPWHTQSQLLHEVALAVQKVDPTKFFHFSELLFKQQENFFDVNVWDKTRTEIYNELLVIVESIGVDKSKVSEYLKLSRDGKNAGNGVTNDLKKTIKYSRQNSIHVSPTVVFNGLIDNNTSSSWSQDGDINQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U811</accession>
    <name>A0AAD5U811_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-hydroxybutyryl-CoA dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006726</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U811"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075">
        <property type="entry name" value="3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48075:SF5">
        <property type="entry name" value="3-HYDROXYBUTYRYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="4">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="3">
        <location>
            <begin position="185"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3228101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="28954" checksum="147AC2E3F8C797B9" modified="2024-05-29" version="1">MQFLIKRTYSTIKKPSLLGVVGAGQMGLGIALVSALKAKTPVLLVDSNSEQVQKGMKYMDFLLSKDVLKGKITESEKKDALSLVNTSDTLSDFENVDFVIEAVSENPALKRQIFSELCKITPKHAILATNTSSISITKIASSTKRPEKLVEIIPGLATSNETLVATLKFAKEMGKITTQSNDTPGFIANRVLMPYINEACYVLQEGIATREDIDTTMKLGTNVPMGPLTLADFIGLDTCLAIMKVLHLQLGDSKYRPSPLLAKVCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U832</accession>
    <name>A0AAD5U832_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000136">
        <property type="protein sequence ID" value="KAJ3223284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U832"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="582" mass="69181" checksum="2852A8ED20172647" modified="2024-05-29" version="1" fragment="single">DIPSHNKKKNRKRKKRKKSDDTPIIENMKQQKVKPKSKKKPLEYFQENILKDNHVYIDPNKRYLLYCLGANGKKLRRKLEDKNKNLQKQDVYERNGVRNYNLPIPSRKLLDPIAFSLYLKDYFDRFNQLEKHYKHSLFGKLKFNAFINTQKLESKFIKKFKETFGDSENTTVLIGDWSRSAIKYQAGYQVCLVNEFLTSSICPGCKSRTLETFKERQHPNPGKKENLIKVHGLLRCKKENCKQMMNGQLVEKVWNRDDVATLNIKDVVMNTLLHKVRPVRDLPSRAYDDRHNRYNRGGGSRGRGSVQRGGSSFSRGRPLGRTYYSRPLNYNNRDYYSNRDQYNRDYRERDHFEREYERDYYDRGYDRGPYDRNEFERDRDRFDRDYMLHRGGFEDTLLENRDTLLPPREPIVSQQPELNSPQRGELSPIPPSDFTPKRPATLQPNNHQRNGQLSQPRLPVPLQKQPSFSSNNQQPIQHQQILTSQHQTPRKHNTPKPPPIPKQPTELSSSTFNENSSTRQLYLFKYPLTEAQYNESNRLIGDYEKLQLEYEELLKVKRKLDFEIDFCDIEYKKHSLLFKKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8H7</accession>
    <name>A0AAD5U8H7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP synthase subunit 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ATP5O</name>
        <name evidence="18" type="ORF">HK099_005569</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000044">
        <property type="protein sequence ID" value="KAJ3226100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8H7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="17">
        <location>
            <begin position="28"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3226100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="535" mass="59541" checksum="F53A0C3C1DF99923" modified="2024-05-29" version="1">MFSSNPYLSPPTPTLHSPKGSSNSINLRKGTFVQKLFSILSNETFKTLIYWSDSGNSFFISDVEEFESKVLPLYYRHNNFTSFVRSLNMYDFQKVSKGLRGPPGLKQSASTKQELWEFSNVHFRRDANFQQFEKIKRKLSIFERSCSITPKAPPAFSKSFSQQDNQSCHLTVNTNLATVSKLIPPSPKYSPQHSIYSSPQYTAFSPSQHEILCNSPSFHAFSSPSQKALSPYLKFTILPSPQQLNSPASKSVYCQSPLSKTPINPTFGLENSTTAFLGTDVEDEEDNELDLFFINLQMENLQEKLKNLEGTVKQVKIDLKAEKLKATSSSNIMRNILNIMQIKFQSQPANDVKNTQATSSLTLPLTSASFASVASTPAKVPIALHGIDGRYATALYSAAQRQNSLTQVHQDLKSLQQKINADKQLKFVLETPIFGRDIKLKELKALLSKGSYNKLTGNFFNVLAENGRLDQVEKINHNFDLLISASKGEVTIIVTSAQVDPAIVGGLIIEIGEKTIDLSVSAKVNKLNRLLSEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8L4</accession>
    <name>A0AAD5U8L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005501</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305:SF28">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305">
        <property type="entry name" value="TESTICULAR SOLUBLE ADENYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="125"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="396"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="696"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1306"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1783"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="709"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="733"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1318"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1786"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1805"/>
            <end position="1830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1848"/>
            <end position="1863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1872" mass="209513" checksum="EBD1A9CC7DE398AD" modified="2024-05-29" version="1">MKSMRLNIGERRMSLALHLPNPTPNSNSETPRTPNIENDNSSNTYNGLRYESIVPCFVSKHVKNYCDNACWSQWQESVEEEMKRKKEIKTEQEEEEVESLEDIFQSKMHQFITDMQPSANESFAAVVMADVSGYSKLSASLAERGAEGAEILCRTMKGYLDKIIDIILKHGGDIVKFAGDAVIFYWKLQKFDPGGSPVSIKDEEVNKGEIVLKAAHCCLDLLKLLGSYEVEIPEIGMQVLRIHLGIGAGHVYDVAVGGIDRWEHFIAGDAVNQLASVLDLAKAGELALSHQALKCFSTIVDIASVGIGSYDKRCIILTGLENAKNRARQSLLAASPSLTEDGHSFGPKHSMILQAPQGVNIAEEHLTTVQETALELYKLYINPSALYKLQTDINQSRLFKVDAGLTELMSLRESRQITTIFIKLGSLTKWDTRATVDAAQEAMSIVQEALRKYEGSLRQKHVDDKGATILIFFGLPPLAHENDASYGLKAGLEICERFLNVFDDFSIGITTGMVSIGGVGNENRIEYAVMGDAINMAARLMCSVKCKQTILCDEKTYNMCDNEFLFESLGEIKVKGKSHPIAIYTPKKIREESTKKNLNAETFVILGREGERKLIEESLEAHATSNGPRMLVIEADGGMGLSTLARWTQTEAEKCGYRIGTGHSAQMEKSTRYYIWREIVNDILTAIEAMEVKENRVASETRTPTFLMDKSEHGNDKISKVSMEEEGGRRPPGTQSHSQQQQRTKGQIKSSMTNKKSEVKEFPANGASVLNSQSASWQPQAGAKISVREKKFKQVVLTTADNSHTSNFRLKTVQSAEAIGTFPESKVSEGVHKKWYAFEERLRQAFIKCGEAPTQTALLNLIFPFEFNQSEVYAKLQGKFRINELTDLVRRIINVLTEDNPMVIMVHEAQWMDPLSWELLWELGVSCPRVMICIFSRPDKYHENEETRSSYLKFKRHPRTEVFTLEGLSTEETSKVIMQNYPSPIQITSISSAIIENVQKRTGGIPLYIKSMVVALKESGHCKVTESGELKLNKDDFDFEKSVAVGGNLQSVLVAQFDRLDANFQLFLKVASVLGQPFLLEDVLYLLSDTPGFNEMFQGDTIELIANQIKALDKYSFLHRLDGDLDGVLIQFKSSVVKKSIYTMMVISQRQQLHLNIATYYERVLDANNRHRLLLPLYEHYSETDDKQILKKLSYLEAVAHVYFEKNSMGEAIKHYTNLLERAEQAMKLPHKPATFDAVTKSTWHRELGEAYFMKGDDQRCEHHLLECLNLLGQAFPKNPIVLSWKVRTQAATRSQYPILLSGDTQTTSAPSQFPDVNDQNSQGSLTSMSTSNISKAYEAARNLVSEEMQFNPMAIELAEMLRDKKNLGLHNVRRALATLAQIYLNTGQIKEHTYAVFKGTNVSEGFPHDALYARFLSMCGALSWFSEGKKRMALRYLESASKHDQRLDLSHTVSIVLSTALTLFLMGKWGSSMRRLAALPFLEMMSGDCSMRAEALRMRAIVIHMSGARSQSLKASRDLFAIATQEGNWEGKVWGCKMTLANLLTTTQNDSEIAEMSSKLKLLWAQIPERHKGDPILGMNHLGLTSEADFRLNSGFLLENFMKILLEHASELRNLQNRRKHSRSANASNAWGGGAASAGGPHHWLALAGLVHCAAVLLGVFDAGLGSEMSFRKNVEKVCTDVEDWLGKGQIMRHMTLAHPIRYMFKGIRYLIRNKAPPRAIAAWKKGLACRRVSDLLYVRGLLHLRIAKFSTSNSESNHHAHEAQKLLRRIGASYEFEKATALRKDKKRKHGKQKKMRSDEHGPSGVPSGGAPESGSEMESGMESGIESKSYGQSESKSYGLESKSYGYTESKSYGMSVNDQSYDDRSGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8P2</accession>
    <name>A0AAD5U8P2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007157</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000067">
        <property type="protein sequence ID" value="KAJ3225239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8P2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="30646" checksum="C57613DEBF3BEF5C" modified="2024-05-29" version="1" fragment="single">MSSVPKVDDVTVTTMITVDRFNTLLNSISTTDCYFSVTLHIPDDEELVSNMEKLTKFIDKNFVVLKSKTNIHLVIDKYPRQLNYLRNVARFFSKTEIIFPLDVDFIVNKSFLKNFKSNEFVKSKLSIGNSVFVLPALEFQNEYVNTKFNDFPQTKEEVISMFNNSLTVFHGLKNRGHSSTNYEKWLGTDRIYQIVPDTLRYEPYALFNTTGVPYSDERFTGYGANKVAWWYEIYLSGVEFYVLPNDFVIHCFHEYPDIRIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8S7</accession>
    <name>A0AAD5U8S7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">2-oxoglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">2-oxoglutarate dehydrogenase complex component E1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">KGD1_1</name>
        <name evidence="18" type="ORF">HK099_000389</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 2-oxoglutarate + H(+) = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:20092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000109">
        <property type="protein sequence ID" value="KAJ3224012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8S7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1150:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12470:FF:000003">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase, E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="17">
        <location>
            <begin position="600"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3224012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1145" mass="129075" checksum="D2732A0B3DC22317" modified="2024-05-29" version="1">MYSAWKKDPSKVHLSWQIYFKNLTANENYTVSSPLPPTSAFPSSSSPQILHSIGGDLMSYETGAALPANVNQADIKDHMKVQLLVRAYQVRGHELADIDPLGIHSPTVNSAPELNYKHYGFTEADLNRSFQIGSGILPRFKNGEKNKTMTLKEIIEALQKTYSKHIGIEYSHISDRTMCDWIRERVEIPTQYSYSKEKKLVILDRLIWSESFERFVAQKYPSEKRFGLEGCESLIPGMKAMIDRSVELGVASINIGMPHRGRLNVLSNVVRKPNESIFSEFTGSLDNHVEGSGDVKYHLGMNYIRPTPSGKMVHLSLAANPSHLEAVDPVVMGKVRGLQYYQNDTESHSKAMGVLLHGDAAFAGQGVVYETLGMSDLPSYTTGGCIHIIANNQVGFTTDPRFSRSTPYCSDVAKTVNAPILHVNGDDVEAVVFALEFASDWRAKFKKDVVVDLVCYRKYGHNETDQPGFTQPLMYQKIKGMTPVAKKYVEQLLSEGEITKEEIEALKARVWDILEKNYEASKTYKANSAEWVSSTWPGFKSPAELAAVTVTTKPTGVNKGMLEHIGRQTTLYPEEDFKVHPNLQKILKQRRDSVLNGHGIDYATAEALAFGSLLAEGSHVRLSGQDVERGTFSQRHSVLHDQNSDALLVPLNNLVVPDIVSSQAHFTVCNSSLSEYGILGFELGYSFVSPNQLVMWEAQFGDFANTAQCIIDQFISCGEQKWLQRTGLTLLLPHGYDGQGPEHSSARIERFLQMCDEDPYQMPDPIGTEKKSYSRQHQDINMAVVYPSTPSNYFHVLRRQIHRDFRKPALLRHPLAKSSLAEMEEGTRFQRLIPEVLHPNPLSTLRIANEASELAGAPHWQRNNAEPRIPYGLVKDPNFPLEAKLASVEVSSSSMQSGDFRLLPPNEIKTLIFCTGQVYYLLHRARSLNELRHIAIIRIEQLCPFPFWEVQRVIDFYGESLEEIVWCQEESFNAGAWQHVEPRFETSIRETNWYTNSKTSANDVNVEEISFTNNTTNHEKNEPSFFKKLFFSKKKTPSSPNNNNKENNNQIINKNISKVAQKWAETLDKNRYAGGLENIRKPNRLPKSVRGGRFIRFAGRDQSAAPATGIKKQHKFEEVTLVSEAFFKGELKKPVDMVQGIPKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBX8</accession>
    <name>A0AAD5UBX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBX8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042170898" evidence="2">
        <location>
            <begin position="23"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="429" mass="49088" checksum="4FF50EA61A89B9A0" modified="2024-05-29" version="1">MLINSSLATLVIIATSSLLVLSAPSSYYAGDDNYVQHYKHKYNRHKGYSRYHHKKHHKHHKKKYYLSADATDDEDDEDQDQSLTADSKVASLTSSSLTVYPGKPHHKGFKGWPKYAPKWATKYKWKIDKQGTLTEIFTGPQKGNFGDRKETWITYADGREEKSAVALRADDVNEDDATSEQSLVSQQATVYPGPPHKRGSKGWPKYAPKWARRYRWTLDSKGTLTEIFTGPQKGNFGDRTETWVTYADGREEKSAVALNAEGSEAEQSLTSSSVDAQELTAYPGPPHHIGTKGWPSYAPEWARDYKWNLDAEGTLTEVFSSPQEGNFGDRTETWITYKDGREERNAVALRPEAADFDDDDDDVNFEDDDDDDEDDDEGDEGDENEQSLNSQDSYGSYDSYNKYRSKKHYGYRKHYKKHKKHYYNKDYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC27</accession>
    <name>A0AAD5UC27_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC27"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="291" mass="31904" checksum="8526EF370042E7A9" modified="2024-05-29" version="1">MAKKDKPTLTESSVELDITTDTPNASQCLKVLCAVTNYCDSSNGKCLNFTGILESCKSNEECGPDRYCGLSKKKNFGYIGDFESSKSSEFSTVCRYNGSGIVKQKCLDTTDCKQDLFCYNDVCTIRATPGVTSFRSKDSNSYPVFSNTSIVLFGSSLILFTFFALLCFGLKRHMIKATALNEDPNIADTTTSDAVSVKSIDTLPTYRTSVTVVSQYEAPTYSQLDENEIDVVSLPTHSRNSTISNLDRSSIVQLDTLESNESSDQLIRSNSVHSIISLPPTYDNATTVHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XR93</accession>
    <name>A0AAD5XR93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Vacuolar protein-sorting-associated protein 24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">VPS24_2</name>
        <name evidence="1" type="ORF">HK099_003476</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002277">
        <property type="protein sequence ID" value="KAJ3198731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XR93"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="85" mass="9687" checksum="F86D2B1E66673961" modified="2024-05-29" version="1">MREMSMEMMKAGIIEEMLQETMEMDDDEEMEDEANEEVDKVLLELTQGILGGVSAPVGPELILEKNETVKPEIDEMKNRLEALRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRN9</accession>
    <name>A0AAD5XRN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002328</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001760">
        <property type="protein sequence ID" value="KAJ3201247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRN9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000001">
        <property type="entry name" value="zinc finger CCCH domain-containing protein 15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000002">
        <property type="entry name" value="Zinc finger protein 36, C3H1 type-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="292"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3201247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="601" mass="66632" checksum="D967C7A52C584B56" modified="2024-05-29" version="1">MNGLNPSNLYSNSLPRPLHFENNNNLYDNKLNNSDKNHHISNSLPLDYMKSLDPDTVAFAEAAAKAAFQDAIATRTARISSSSTANNNEIGFKETPPRQSLKHLTFLNGAGAPLTPTSPTRPTTLMSPSLLSPYNDAHQSSPFANEFSVASPNNQRKPVSVPRTPIRMNQQQIQNDRNRLYNNDPSLQWSNSPMLIPTSPTGDTSNESEDGEGKDRDSKKMNLYKTELCRSWEETGTCRYGTKCQFAHSYVEVRGIDRHPKYKTEMCKTFWEKGTCPYGKRCCFIHTTKDSTPMSPTNVTPPRQRSNSTSTRPLMDDNGDTPRRSKPVGIFTGKPNGNGELNKSLFDQVTGGFSLWSPTVGSPDVTQAFSFSERSVQESMFRNQQQPFGSVPNSATPFTRKQQNYLDDLNQVDQGMKSFQISSPLNSVPTTNVLTPIQTRFDSDASPFPRSTMSTGISTQPFFNSNDLNFDEEVNNKSQNNQQIGDLFRVRSGASSLSHVPILNTPPMRARVVSETMGFNNSSPIESFFKGILDSGETTTSGHLKSLPVHQRTVSSPNNYAQAFKQQTLCSDEVLSPHKSIGQGSLRKFDSGVNIDLQKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUA7</accession>
    <name>A0AAD5XUA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase eIF4A</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Eukaryotic initiation factor 4A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">TIF1_1</name>
        <name evidence="19" type="ORF">HK099_006494</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000563">
        <property type="protein sequence ID" value="KAJ3215163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUA7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18046">
        <property type="entry name" value="DEADc_EIF4AII_EIF4AI_DDX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044728">
        <property type="entry name" value="EIF4A_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022210">
        <property type="entry name" value="TF_GCR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12550">
        <property type="entry name" value="GCR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 19" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="41"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="240"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="441"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="510"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="832"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="10"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="568"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="844"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3215163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="854" mass="97067" checksum="CE5BD96383BAD3B1" modified="2024-05-29" version="1" fragment="single">MRSNWDQVVEKFDDLKLHQDLLRGIYAYGFERPSVIQARAIAPVLAGHDVIAQAQSGTGKTATFSISILQTISIELREIQALVLAPTRELAQQIQKVIIALGDFLNVDCHASIGGVNTRDDARKLESGPHVVVGTPGRVFDMIYNRRAFRTNELKMFVLDEADEMLSRGFKDQIYEIFRLLPTTTQVVLLSATMPVDVLEVTKKFMRNPIRILVKKDELTLEGIKQFFVGVDKEEWKFETLCDLYETVTIAQAVIFCNTRRKVDWLTEKLLSRDFTVSAMHGEMTQEEREQIMREFRSGSSRILISTDLLARGIDVQQVSIVINYDLPLNKENYIHRIGRGGRFGRKGVSINFITAEDQRMMREIEEFYNTQEETSKLNEKIASLQNDLKHFSQQISYVPLIDSVTKAVSDASAVASKTFFESLEKIFFHFDNKSLNGKKTTNIKQQQQHTPQSASNSMASTPPNQNFLAANQYRNSKNTYSHSPQTSHQISSNLAQNNLQTGMRKEISMASNGAPSTGQTPQGLPNASSHRYSSPPQLVQQPRFTNAQTNGMKANTTISSVKQNVRPPQQAAPSSSPPFLQQPVKNSELLQKNLHQQQQQSIRVIAQDPNSNEQAQHRAQYYKNSQNQVSNANQSGHFLQSVNKPNTQIITESQQNMITSKSEESKEDNRVFSEDKKFRKLIPPGAETFTLDRSLKTVREVWNEYINGVNGNFSLKKMEDLKMSGVYNWRSSNTINRSFLRSRKNILEFILSSTRSNFVNTGEIDEIENERNRLNVENCLKLLDEKMLKNPTINSLNKLNAFLKDAGDVKDRSIEEMFECLERIGFSANNEEEENVSQNVSDFDERNDLPEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUJ4</accession>
    <name>A0AAD5XUJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001876">
        <property type="protein sequence ID" value="KAJ3200571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUJ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="129" mass="14713" checksum="B650B8AF090C0199" modified="2024-05-29" version="1" fragment="single">FVVSYIKANVSLVTWIYPADCTLENLSASFSVVTFTCTKPQQNLRFQAYDSNDKSAVQDFYINLEKPFGCYEWYFISGDQSNYSLDDVPTSLLNLVNPFTKVLNGRIWVVDKEFESLDESNRIAVLPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVD3</accession>
    <name>A0AAD5XVD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">40S ribosomal protein S4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPS4</name>
        <name evidence="8" type="ORF">HK099_002865</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001999">
        <property type="protein sequence ID" value="KAJ3199976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVD3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06087">
        <property type="entry name" value="KOW_RPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000005">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.740:FF:000001">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_eS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032277">
        <property type="entry name" value="Ribosomal_eS4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013845">
        <property type="entry name" value="Ribosomal_eS4_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038237">
        <property type="entry name" value="Ribosomal_eS4_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041982">
        <property type="entry name" value="Ribosomal_eS4_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16121">
        <property type="entry name" value="40S_S4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002116">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="7">
        <location>
            <begin position="15"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3199976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="220" mass="24993" checksum="17C47ABA265304F0" modified="2024-05-29" version="1" fragment="single">APRPSPGPHKLRESLPLIIFLRNRLKYALTGKETTSIMMQRLVKVDGKVRTDVTYPAGFMDVITIEKTNENFRLIYDTKGRFIIHRITAEEAKYKLCKVKKVQLGAKGIPFAVTHDGRTLRYPDPLIKVNDTVKVDLETGNLVYITGGHSMGRIGTITHRERHHGGFDIVHVKDALDRTFATRIANIFVIGQGVKPWISTPKGKGIKLTLEQERDRRREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVT3</accession>
    <name>A0AAD5XVT3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">O-fucosyltransferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001566">
        <property type="protein sequence ID" value="KAJ3202480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVT3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3202480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="41419" checksum="136BD7A3F6F50589" modified="2024-05-29" version="1" fragment="single">EQINNQLIEFKSACAIAHELERVLVLPLIGHRSAQTDADWDFTFKISEFHWVPFEKYFDQKEFHNLPCRVISTNNFRSLHAADPNFTLGTLHFNPIAKATNEQQMFDYFNTELNFPFTNITNIHGRMAQLSSSEIYTKFGNDNSNILGIGATYWMHGFERFQPYPLTQYENYMDHALYRKIISGLKVSDNLKNIVDVGEAYVRGLLKAPIFVSGKGQTNTGISLSSLLESILEKKANIGVGNKSKFIAMHVRRGDYWNKCKRIKSPELRSHCYPSPGKLEAVVQQYLGEEKMKEEQNSGLFEKQEQATNQFDVTLYIATNIGGSKDEFKSLRERYNVMFFEDLFLNTKGSNLDSSHMALID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW89</accession>
    <name>A0AAD5XW89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002272">
        <property type="protein sequence ID" value="KAJ3198753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW89"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3198753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="26898" checksum="7ADE808E6F575B19" modified="2024-05-29" version="1">MSELVQPKAKSQQPQGQLADLLKGRLEWEGNGSSPGLRSNSAPPTQIFNNENDVNIENSSDPRLDPQYAAYYHLHSRLDPRLPPPLMYTPGQSWQQQMWAPPPFKNKFNDEFDTDFNLKNFDEFTNNNEELINSNIHRDDTLSNSRIPDFRRPQPVWNNDISPVQPNRVGSPSRRKHLLDLVQDDYPNNQASTGFSLRQPHHQFDDLDHEINYLHTNVLSVLDSREDFKVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWE6</accession>
    <name>A0AAD5XWE6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000217">
        <property type="protein sequence ID" value="KAJ3221650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWE6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="262" mass="31148" checksum="BE220D9E06BF72E0" modified="2024-05-29" version="1">MIKNQQYNRELELIRVKIIQLIDTMEKFLNLPHNANWQTILPQFNVLIAKYESLLSELEQPVLKKLIIHPQVLLADDPEFFARVLFRTKLIPEIEELEESILNFKQNTSKILPNANDNINILDENMVKNNLRNWEIKMERHDQISIQALKLFESFKNEFEYKKRLPIEVEDLKIKDEEDESDLEDFDPDKITKMEEVEETLMEEDQNDLELEKVLQDQSNVLQKQKKLKKKPKKRSIKLISSTLLKVELEKIFNFLSSGIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWS8</accession>
    <name>A0AAD5XWS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sn-1-specific diacylglycerol lipase</fullName>
            <ecNumber evidence="14">3.1.1.116</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_008642</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:33276"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="14"/>
    <dbReference type="EMBL" id="JADGJW010000975">
        <property type="protein sequence ID" value="KAJ3208828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWS8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046340">
        <property type="term" value="P:diacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF8">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="17">
        <location>
            <begin position="882"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="402"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="411"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3208828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1132" mass="127555" checksum="1D3572E1CD9BB703" modified="2024-05-29" version="1" fragment="single">MQPQIYKKNSGSKLKKLFKKTSSQPMTVPHQSLPLSTYNNQILNTQSFSNQSTSKKQKKSKKKHSLLKLLTHTHHHKQLKNNNNTQSNHQNSQNPSSLIYPSAVQVSKPHDPDISLAVSDIINTVLTMPRPKNSNFELDEEKFKKKKKSGYYNEAFLRIDSSDSIFSDITEEEDDNFIESSDEEDFDYDKNFDLVYPNANLNLYLDSNSCSLNSEFYNNNLKCDEFINYDPTTKSGRANRYERRQSNSNSSSRRGSSEDRLQVLGEKWGARRASLAKLDELLKEVENYEENLLNVEEGSIHSNYEEILEEYIFEHILQSEDEISDIDTANESNNLHKELLHYQMVSDTSNMEKTIPETNNPSLTITEVTDNFVNENTVSNNLIYEEVSGVAPSIKITEVTDDLSNDDTHTSDITSTEVSPVTTPLTSKSDDLFHSMDEGSVTVRNSSDHEGESLNYDEFANKAIPDEKLNRNPVKRSFSRVRRICRYQNGSEPQNITKVEVFCEDPNSSREWKLFEAPERKDSVQNNVNNDNDALTETSYSTTASTTMAATISELKETVSSLTSEQIPSECEITDYIVTEPEDVVEDVTEKPQLDLKKIEQRKAIFNGVGMLVHLATSTAALSFEVAKSSTKFGIRTAKTVVDGVGTATGITLPTSLISSTLSVAEWIAITSIETGRFWTDFGLESGKLTLEVLGIIFGSSDIAISIKEFTSLVQKQEIFTDKDGLELSYSQVLRGLTAWAYLQSTTEIEYTKSKWIPSMTLIASTPLNNSLQLVSEPVGVNKFIPIDRENEEVVNLLENVKHFIHFACGAYGSNATSLLWSRLPFSSNSMWLSPRNHYHFARHTGISLADIRHTSHSQYNDLHNYHPQFYVVLDRKFNQVVLALRGSLSLHDFLIDLTCESEEVILLKDNKKTTVDVHSGMYRAAKKICDAKNSNPIFTAVKSLLEENPTFGLTIAGHSLGAGIGTLISLIWGDLDTALTKPESGLPPNRTITCYAYGSPCVISLNGVKLCESIVKSITVESDIVCRFSLGSSQDLRNCSKWLINNREVMDKLIKRMLSTKKNSQEDFALRLEIEKECLNSKKLYSAGEVYYLNKFNLYRVNDLETVFNSLILNRGYNHHLPSYYDKIIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX54</accession>
    <name>A0AAD5XX54_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000138">
        <property type="protein sequence ID" value="KAJ3223236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX54"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057688">
        <property type="entry name" value="DUF7928"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF2">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7928" evidence="2">
        <location>
            <begin position="147"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="1">
        <location>
            <begin position="524"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="691" mass="78430" checksum="48C90D59DD515F13" modified="2024-05-29" version="1">MDTPVSTLNSSSSSIRSFQSQSLTQKSSIFIAERLHNKILMKGLCKETDNCFVAVRKTLFLSLPSNAPNSTFDGENLSLKIFSTSSLQASANSTFKNDSLMNTSLRHQVNTNTSIPYWGESPLSPALKQPTISFNDAFSFHSKLTCSADDFVIRPDAADNFFADYIKGFNAFYFVIVSSNTIRGALNTVPVQNQSIILKENVDENDMQEFANLQILPSIKHIHLARKHQYAALLREENCLAVWSDSDTMDQVFNSIQELDKKLFQVVWEGIEQKPEINDSDDVEDIERQSDESSLISDKVSEVNKDFAVLREPPYVDLELNFFTRRTFSVLSTIFVTISLFSPLNRNSNYYSIIPPPRKNLLHKQIFQENRKGKNMSILPHVTIQIPVYTEGLMTVIDPTIKSIKKAMSTYEKQGGTASIFVNDDGMQVIPETEAYERQVYYARNDIGWIARPKLNRAGRFKKASNLNYCLNISKRVRDEFEICCTKNSKSDSELMSPEQCLYKVFQEEFPDAMGAGDVIIGEFILLVDADTRVPEDCFLDSVNEFLSCPEVAILQHDSSVLYVTNNFWEKAIGHFTKMTYLNIRFMSACGDVCPFVGHNAFLRMDSLEEISTVDSLGRIKYWSESHVSEDFEVSLKLQSIGYVVRFVAYSKGKFQEGVSLTVYDEINRWKKYAFGCSELTQLDQLGFSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX92</accession>
    <name>A0AAD5XX92_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007887</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000807">
        <property type="protein sequence ID" value="KAJ3211905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX92"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="343"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3211905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="371" mass="42480" checksum="00D5E3E9D04A661A" modified="2024-05-29" version="1">MQMKIHENTQEWLTIQKSFGNCGDRLKPPASSYKTLSNIPSPPISPSFSMQSNLYANETEQIFFFNASPSTSMDTFQYFEQIKAPEIPFSPPLSNPDIVSMDLGLDSLTDHQDTYINTYNNQPVDYGNIVNTSMWLEEETFSEFNNASRFVSDDFLYIEDQISRPDSTVSYYSNNFDDSELLQSILQHPVPLNHGTFCGYTSPPDANPEPTLFSNITPIAYTTLPVPVTNISSESVPEAKTCEKRIPTPAQKERSSKTQPKLKTELKPKPKERILKKTQPKQPKKRIEKFSSKPVVKVEKNNQNEIPTDKNQEIFPCPICDKIFIRSYNLKSHMVCHSGEKLHGCIWRNCGKSFARKHDLLRHQKNLHKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXE8</accession>
    <name>A0AAD5XXE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit C</fullName>
            <shortName evidence="4">eIF3c</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 93 kDa subunit homolog</fullName>
            <shortName evidence="4">eIF3 p93</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Translation initiation factor eIF3, p93 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">NIP1</name>
        <name evidence="8" type="ORF">HK099_005700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000458">
        <property type="protein sequence ID" value="KAJ3216831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXE8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03002">
        <property type="entry name" value="eIF3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027516">
        <property type="entry name" value="EIF3C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008905">
        <property type="entry name" value="EIF3C_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05470">
        <property type="entry name" value="eIF-3c_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="958"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="383"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="561"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="533"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="562"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3216831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1227" mass="142147" checksum="46A2D1C989205F08" modified="2024-05-29" version="1">MKRRLQVHSKATKAVEVVQNSSLSFDYASSNEDSDESNQPQEANSATSESVLKGDEELNKFLQEVHSINSNGSILEENLEKKATLNVKETFDLDFSTSSQRENIKERLDMLKNNIKPLNNFPQHINLQCLPAIMQVQFDPKKDQEKIEHIQRLSKKIEGILLKSTNEEFLSRLKKSKIEFDSRCYDWYCGMLREEYFMEIIYHWDSMVQKLEGEDLEVVMKLQRQTYNLSIEKPYSSKEAGLHQTYDTELENVANNRKIYTNDESYSNNVVSKPLKKKAKNQNMIFEKWNLKKEEIEMEEEKMFQQNFNDSSISNVKKLEAWAKKEAEEKCKYFAITMWSDLEFIYKMSKFFQKHNSSSEESESDSDSEKDFKLKAKPQQIKSKLFGKHGSSSDEDSESDADDQSSTHSDQESFREIQETKESGRDRFIKGAEYDSDSSSDDGNKKVLSAIDKKNEELRANIKILNNSKKIGSWVSVQAEFDKITKSFDKSKNLFPEQKPPRYLIRTLVQLDDSLKVSLGEKDKVKKMKALEAKALTAMKQKVKKYIKNYEAEMEAFRENPVEEIDSGPEWSDEEEEKPKEVKKKKSRKALIAAAEDAENLEGWNKIESGKPVVALSMENLFKKLKELMDVRGKKSTDKLVMIKELRTLLNYSKTPYQKCRILLALIPAEFDYTNAAGYMGIELWKTTASDISLIMELLENHTNITVKDGVEEPENDNELDKLAVAGENVELLGNIGSFVDRLDDDFRKSLQHIDPHASEYIDRLKDEQFLYGLIVRSQSYYQSKTEKVEDVLAYGMIMLRRPESVIKIVESAVKRDNPKFEHLFNENPVDSLCVQLYKTANDRIRTRALLCQVYHHALHNRFYQARDMLLMSHLQETVQQTDVETQILYNRSMVQIGLCAFRLGLIRESVNALQEIQSSGRVKELLAQGISQQNNRYYQNEKTLEQEKSEKLRQLPFHMHINLELMEAVYLTGSMLLEIPNMAQNSHDSRKKVISKNFRRMLDYNERQVFNGPPENTRDHIMGAAKAMAIGEWESAVELISAIKIWDLFPETEKIKEMLEKKIKEESLRTYFFNFSKNFDSILIPQISKMFDLDCEKVLTVLSKMIINEELEASLIESKNLIMFNNSLINSNKLNQSNQQNVNFNKNEFSKLNYLAGVYSEKVFGFCENNEKLFETRLFKDNGGYNQTGGYQNTGNTGSYGYQGKNFNSNKSYGNKPYNSKKNVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXG8</accession>
    <name>A0AAD5XXG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EIF2C4</name>
        <name evidence="5" type="ORF">HK099_000539</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001124">
        <property type="protein sequence ID" value="KAJ3206445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXG8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="3">
        <location>
            <begin position="350"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="4">
        <location>
            <begin position="657"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3206445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="944" mass="104944" checksum="998DD196BC76F57B" modified="2024-05-29" version="1">MSSRQGSARGPQQGGQQGRGQGRGDGGRSQGSAGGQRGNGQRGGPRGAGQGQGGRSQEQQGGGNQQQQRYGGPPSSTGSQQRPTTGQQRPTSSSQQLESQFQRVKIGTNAPISVDDAVKGAMTHVARPNFGRLGRRITVIANLYKVSIPDRDISRYDVVVKPDKVPKPVCRRVMEHWKNMDHSATLGWSTKDKENVKNIAYDGQKLLYSPFPLKNIGTSFSNFNIEMADDVGGNKRTFTLSIREIKPVNMSVLLEYLDPSPKAVEIPSEAISALEVILRQSPSLRFTTNPAGRCFYSDKGVSTLPGGIDVHYGWYQSLRATLGIQQEQYSYKELLLNIDVVATAFYQQGPLLNVIANFFGKRRIEDCQRSFTSKNDLRKLDKFITGLNVIINYRNTGRRKYKIKGLAAQSVQDTKIRIKDDDGVNERTTTVQQFFRNTYNYNVKYPWMPAIVSGANNVQIPMECCDVLPNQRYVKKINEEQAADMIKVTAVLPEKRKLRITEGLSNLHGSNDKALLNNWKVEINNNLKQVEARVLDTPSMTFGKSKPQKIFNNGSWKQSGFAKPGILVSWSVALFGGCFGRPGGRDFGILEEFMNKLGGGLTSQGVEVLWPDTTEEMTVLEVRGDIRQTLINAKNKAAEVGNRFKNAKRSNGRTIDLVLCVLPPGKNAHIYNEIKKVAETDLGIMTQCLQQKKVAEQKGGYFQNLILKINAKLGGVNAYVVPSDIPLNTGNRVPTRANNGVSIAALVGSVDSGFAEYRSSVRVQAGRQEIVNDLHDMVIEIFEMFRERSKGVYPQKLIVYRDGVGEGQFSEVIYNELKSLKKAFQTMKIKPPTVTFLSVNKRHHVRFFPANPKDGDKNGIVHPYEFDFFLNSHPGLQGTSRPTHYHVFTKAVSIVPAVYYAHLLAYRARCHIEKDDGSDNLSQVSQDLDVSRITKEISNSMFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXL0</accession>
    <name>A0AAD5XXL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_005466</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mis12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000426">
        <property type="protein sequence ID" value="KAJ3217474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXL0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008685">
        <property type="entry name" value="Centromere_Mis12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527:SF2">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05859">
        <property type="entry name" value="Mis12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="13" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0498">Mitosis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="15">
        <location>
            <begin position="278"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3217474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="485" mass="55410" checksum="899AB61F687B496E" modified="2024-05-29" version="1" fragment="single">MTELFDQNWEILTEHLGFTPTDLIDDVINSVNELLYQALNSLEDLLTERFADDDFEKALAEIETLFENSVDKHFDKFELFCLKNIFSLPKDLNVVLPHYETTFFDPLREMKKVDVGIEDDNLDAELENLRSQILAQKYLHYHLCKKVTMNESKLERIFQIQQCLMENFSNELNGKVSTSNLSLRIDDLRLLLKQTKGRCIKSNVEGKGENFFEVVLNVDQRIKFIGNSIQSYLERQNLQKNDSTTNCSNSENNKILNVNEFKLDFHEMQEIGNPDGGFSLGYDGCSFLAFMTVFTCGISLMSCLGLTYDRYSVIVRGNIISRSFVSKYVVGSWIICTLLASLPYMAKAQGKTFALEPSLTLCIVAWESKMNFSFIMITPVFFIAYAYTMIYLKVRQNSKSLSKASDDNKNLSIPQIKVHNTSGKSINHSSLSINKSQCALNKQVAQTKKLENRVLMQSIAIVTSFLGAWTPYLIRILYEVISGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXR8</accession>
    <name>A0AAD5XXR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000084">
        <property type="protein sequence ID" value="KAJ3224713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXR8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="296" mass="32052" checksum="4D2AC8B0977AACA8" modified="2024-05-29" version="1">MSNSAINPAVTAISTSSQNNEIDCQKCSNQFNCINFINSGGSSLSQFTNFTEVYKNCLCFNDTNQTLNKTLIKESEKCSKLANCSTFNATSLLQISQAQPLKLVCENAIIPAFVFSILPNINNVKVIKTATTTYTSDTTFSPATEKPNIEHSDSTTILSPVFTVIVTFSVASTILLLILNILRSIVKKKSLQFDTSTSTFQDPLAFAIEESARISNLQQYPIPPPSYRESILECPPPPSLTETPTSNSTVSTNVIEASPKLSSEYVGCSVHRQVCPVSCLKPNNAVVPINIGTSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXS9</accession>
    <name>A0AAD5XXS9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">VASt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008367</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000091">
        <property type="protein sequence ID" value="KAJ3224499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXS9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140268">
        <property type="term" value="C:endoplasmic reticulum-plasma membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120015">
        <property type="term" value="F:sterol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="VASt" evidence="6">
        <location>
            <begin position="655"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="323"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="909" mass="101316" checksum="9CEEE2F113F81F06" modified="2024-05-29" version="1">MQFEEQNCNLNELTAEKNSFFYPALSGNYNISEESSTATNDSENAKINNNLEIENTSLEKNSNVPFEQISIIQNDSLNLDVNSKENLTNNADRLVESSPSERGNSRRKPSVNYNSILRLDSNINSTVSSTPTEVDLKTAIKALSNEDVTAPQENTKFADNKRNQDFHELFKELPKEELLVEDFACALQKDFLMQGRMVTIPLSDVVSIEKRYVASLIPNSIEFETNSTKAIKLSTFQREGSSFVGSQSDIDSEDSIILINDDRVQKYDSYEFDSIISNGVLDNNELLDNIIDLNLVDTEACNNYDVGKKKDFSSALLPSNLEIKTNPNKDDDSHVLSSPKSSGTESTLKAESLNSAASTKKSIEMLEETKIPKPLDNKSDLNLISKDDWFSSTIKKMVDGTNNIFSSEKKLDDLMAEQQIGDVLLPVGNAKDLDSVDLKSIKSNQKLKLALSKTSPLAPTTTETNISFSSTSLSSPAKVNNILSSILSASEATKITENLNYSKTSNSVTNNEISVVTAASNNSNVTFSLNSTNDINATSNVTNALSSNQLDILRPHAQRGLQDIVNTSENKGKIHSADGDNSTINRISQHILVQQLSISPDRKNFNIYNKPHQPKELMKNLNMYDDVDANDIKLKDSAANVDITKALSDKKTPIHEKKKKTFVECKCDISKMTLVVDKEISNTFLNIVAQNWRSKEDDILAESRDTIHSVKEGEFRTFQYIAALNNPMGPKSTRLSTKETLVNKFTDDGEIRHFCIKSSSQTPDVPSGTSFFTNSRVCVTEKGEGIVRFRVCCEVEFVKSSWIKMAIERAVPEGMKEYFGALISELENWKTYLKDELKNSSSHPLNSISNYQENQTIKNVVAETLVVENEAAPTVKSRVDIKHECKVDKNQIKAIIKDLFFENAREFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYB0</accession>
    <name>A0AAD5XYB0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxymuconolactone decarboxylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000062">
        <property type="protein sequence ID" value="KAJ3225409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYB0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052999">
        <property type="entry name" value="PTS1_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180">
        <property type="entry name" value="CONSERVED MITOCHONDRIAL PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28180:SF2">
        <property type="entry name" value="PEROXISOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="AhpD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="27352" checksum="18F89521DCB1CD43" modified="2024-05-29" version="1">MYAGEIFVNFEMEQIDYKILNNLNNLPLQFENKLSAEKISLIVNAVLCSLNITNLILPFNLKTFELNFKSVDEKRIIIEKVKETFYKISCVVGFPKSINALEQLKVLIFDFESNIENVKIRNRTRVQQVQENITSSGLDLFKTVYGKNSTAVLKKLQASHVDLVETILYNYGLILSDMSMLSVIETEFVLIAALKVQGGMIEKQAFSHILGAVNVGASKVEVDSAVELIEKIKICLMPVIPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYU9</accession>
    <name>A0AAD5XYU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein Zds1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006886</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000622">
        <property type="protein sequence ID" value="KAJ3214420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYU9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040206">
        <property type="entry name" value="Zds1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013941">
        <property type="entry name" value="ZDS1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089:SF1">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08632">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01327">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein Zds1 C-terminal" evidence="2">
        <location>
            <begin position="417"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="623" mass="70983" checksum="7399886658EDA848" modified="2024-05-29" version="1" fragment="single">MNSLSKKANLHKKLSSAFFKFVKVDKTSKLEYNTFGRNQFEQRHLKRESYSTPSSFLKISLTSPNEEISNTKICPSNKPDSQVDNKVNKLPIAEFNGERKRNLKEETAKFVDHDTRLNNESTSSVDRYFASNNTPVAQSNSDSSANNPPTSPTDPDFFSSKRRSLSQSLASPNQLWVPAHAHPEINPADFKSWISSRWMDAGVTDTNINLAKRSSLKRSKSFIENALVLDKVDPSSTNEEEISVVMEKLEDEMKNCDVIKNLPDTPNTNNNDAILTVEHNNLNILTRSQSLIEKGVKQNLFPTPLKRSKGIRGHHNNRSKSLDERPKELSQRINASTIYDTPLSTPKIVTVSDQSHEEETTKTYEGKSKLEKKKGWLKKKWKKLANLSSPQVRIDFNDGRTISLEEEYDEDVYPELPSEFTQNGVQRLPMELEKFVYQLSHQKLSVRGRPLAEQVIISNLMLYIISVHADITLNRNPRKKGKHRGKKMITEMKNTDEKALDEENGFKKESDNKNISDSGCKYIETMDLEGNEVPLRKESLNMTEVLPDLDVEKISSKNCTINVELPFNANKEVKKLDLDDEFEKKILSFEERKKISNPILEVDKCNSDANDEVPLALLKSLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYY9</accession>
    <name>A0AAD5XYY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYY9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="132" mass="15065" checksum="2B10C7938B62DCFE" modified="2024-05-29" version="1">MNPSDAQANSYMALADLDVVDRLIEDEKSIPDIYSYFEIIRNDISNIDKAGKDLFQVKTTFNTFDKSIPMGLMNVTKDKTESDLSQKKTILSLAKSVTRPKFGLKSLSMLQDNLLRTNEIMDDIKRVRKKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ56</accession>
    <name>A0AAD5XZ56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ56"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="551" mass="62218" checksum="A87064F6CE99E155" modified="2024-05-29" version="1">MDQYEFLADIVNSYEPSISTIDKENVPTFPDSLNISASPAGKRYRPPLSKQFYAQKTQCAYINNAGLRCSTLTLNQNGRCNIDLHQQIIEITNKVELILTDSKFSSSSDSSVKSPTNEVKYRMKSNEGKVQCGAVSLSGEKCTTFTKNPSGRCNIDSHQIYNDRADSKFSSGSPKSGSSLGSSLSSNFEGKVQCEAIVAATGLRCKTFTRNESGRCNIESHQKKRDRTSKVLNFETSGSDEENYSETVQCAAVTIYGERCSFTTTNENGYCNIDSHQRKANSISINTKPKLSSIKAQCGAMTAHGERCANVTYNSNGFCNIESHQKQGFSSKRKKTTNVKRIYGICVEDSSDDDSDVIEEISNVMEKENVLDDESDFEEEEDYERVRDNDGRIYAEFCDLYDFHITDKKESVVDIIKNGGLCSKTKDKILKNCSQYAGVYVIQVKPRLGKNWVSVYFGKSENVFEDFDTFITPSGFMLPDSNNSQRTRRFAFQKLHRECFSIQARISYMHEKLVDDKEKQVLEKFNFPLNNKFNGFYRNIRIGRGKIFDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZV9</accession>
    <name>A0AAD5XZV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 56</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NOP56</name>
        <name evidence="9" type="ORF">HK099_004987</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for 60S ribosomal subunit synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000370">
        <property type="protein sequence ID" value="KAJ3218667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZV9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000001">
        <property type="entry name" value="Nucleolar protein 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000002">
        <property type="entry name" value="Nucleolar protein 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="8">
        <location>
            <begin position="317"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="456"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="483"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="515"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00056216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3218667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="529" mass="59265" checksum="380E49F22DC6B3B8" modified="2024-05-29" version="1">MKKKIEAKSFKLTNPVQECNLGFAEGPITWMQRASGYALFERVQAEEIGQEMNEKNMLDLSKFGKVVKLKSFAAFKSAAHALENIMDVSEAVCNDYLKSFLETNLPKTSSGKSSKFKLGVGEKNFAGAIKQELNCECVSDDIVIEILRGLRLHGEKMLKGFKDGDLGRAQLGLGHAYSRSKVKFNVNRSDNMIIQAICLLDQLDKDVNTFSMRCKEWYGWHFPELVKIVADNGIYAKLVKFIKNKNDLSDEHLDELEVICGDSLKAKQILDAARASMGTDISPVDMINVESFSDRVISLTDYRKNLYEYLVSKMHTVAPNLSALIGEVVGARLISHAGSLTNLAKYPASTVQILGAEKALFRALKTKGNTPKYGLIYHSTFIGRAAQKNKGRISRFLANKCSIASRIDHFVDIPTSKFGEVLKEQVEERLKFYEEGTKPRTNDAVMQIAVKNAKIENGEVNSVSPKKRKNDEMDIDEEEEKPKAKKSKKKEKKSKPEKNGIVEEAAEISVEKEKKVSKKDKKKEKKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0E2</accession>
    <name>A0AAD5Y0E2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial ATPase complex subunit atp10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ATP10</name>
        <name evidence="2" type="ORF">HK099_004211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000292">
        <property type="protein sequence ID" value="KAJ3220545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0E2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007849">
        <property type="entry name" value="ATP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28106">
        <property type="entry name" value="MITOCHONDRIAL ATPASE COMPLEX SUBUNIT ATP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28106:SF1">
        <property type="entry name" value="MITOCHONDRIAL ATPASE COMPLEX SUBUNIT ATP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05176">
        <property type="entry name" value="ATP-synt_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="340" mass="39497" checksum="BC0E84B263779510" modified="2024-05-29" version="1">MQNRTLIRLLSSKTNSKSYLPPALDFETTFNTNFNKSSEKKFSKEKNSTTKKNNDTPPKKKDDDEKNLNFFQRFDKRLKDKAAEIRSQQGQRPTGYLYRLEDRLKEQSSKKLAESKDKRKMELKARMDKFFDDDAIKMQREVLLKKAFTKGYFADAKEVAVKGDKFWEAPKVLNSLPTAKQMIKLDCITLAKNKVELSALAKGKVSLVTFFFNAFGEPHVKSYVDPFLEKYEKHTDTQLIQVHVEETWTKVPFLKMLLPLVRKKIPVNRHDNYLLNYEDIEEIRSPIGLTNKLLGWVNLVDSRGFIRWQAHGPATKGEIESLLKNVELLLNDKKASLKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0N6</accession>
    <name>A0AAD5Y0N6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_003830</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000257">
        <property type="protein sequence ID" value="KAJ3221024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0N6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003368">
        <property type="entry name" value="POMP_repeat"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01376">
        <property type="entry name" value="POMP_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02415">
        <property type="entry name" value="Chlam_PMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="14" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0807">Transducer</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="514"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="591"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="640"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="675"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="16">
        <location>
            <begin position="543"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3221024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="747" mass="81648" checksum="1D5C3F8ACDBCA1E0" modified="2024-05-29" version="1">MANKSVKNGGGGIYATTNSKLTLKNVEMFNMTSRYGSAITCLYNSDLHCDDCRLHSSTASNYGGFVMGWLSSTLNFTNSKFIGATADTSGGCFSSVWETTVIITNSKLSNCKSSLTVGSGGAMSSDTTSKFHIDNVLISNSSSYSGGAMYNLGHSVIKNSTFNDNFATGSGGAIYDAGFSVYTDIIIANNTAQVGGGIYTQHDSSVPVRTVTFEGTLVVTGNRADLKGGGFAFESQTIVNLSTSEMKISNNIAHSNIGSSILFGQKKAQLLEGDIIYTGPNNSSIDILKFSTDDDYGQVWFEDLTFASKIKKSGVLDVLNIKAFSPPYSVKLKDVSFNNTKVGEMGNITKIEVFAIDALGNTILNINASRPIVVKVFLSNTSNLKLFGESLKGIINNDTKTAVFDNLVISGLTTASTTEEIVIAPVVLKRSDDIIDHPKLRFIIPFCDPDTSAHYNVTTDALGSVSTVCLPKKSVTQPVKIAFFIVSLVLIFCGTVFGIYAFHNRRMSIYRIASPSFTSLITFGCILQFFSVAISIQTGDTQCILIQWVEVLGFMTVALSIILKTYRLKKILINNSGEINARKKSLSDYHLLKWFTLFIFLTIVFLILWTTLDTPYINLRLMDADESWLQEDHCKGDLNIFPSLVATSFILIYLIASVLAFIIRDIPSHFNESKELAMISYQYIILSAIFFPLSTFLQISENFSYICNAVRVLLPTSVTLAFLHVPRIHSLDVEKATASLKELSRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y107</accession>
    <name>A0AAD5Y107_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003223</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000214">
        <property type="protein sequence ID" value="KAJ3221700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y107"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047867">
        <property type="entry name" value="Ribosomal_uL22_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="32057" checksum="1B63E9CCFFC53CBF" modified="2024-05-29" version="1">MYSQLIRQSAKNKLIFKTFQEYNFKKCFHTKSIQRQQQIDTDEVSPVSSLISDALKESKGITTSLKPNQFREWTFKSDVIDTSPHKCLLVIKTLRNVNLRQALTQLEFSKKKSALKIKSMLNRAFSSINHQINQKMKANPNTRPPPATKDHLELKTMIVGKGIYRRDVRYHGKGMSGRVHHPTCVVKVTLREIIDEKIVDLYKSQLIGKKKTDFENLVDMYKKGFKSKKVKNQLSLSDNRLLLLPTPWDKKGWKYLESKKWTNPNCVLKKKLKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y155</accession>
    <name>A0AAD5Y155_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein FAM184A/B N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002962</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000201">
        <property type="protein sequence ID" value="KAJ3221929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y155"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870:SF9">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="130"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="243"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="351"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="443"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="826"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="957"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1029" mass="120072" checksum="4C98F311133C3496" modified="2024-05-29" version="1">MSKKSAGGEIQKAQSLKSVNKYDGSISSETSYKMCKKIAQLTKVVYYLNTKNEDHSTEIKSLISAYEDEINNIYADGNSKIEEANQIAAQKDIELRAHEDVIKSYLDSIAGYEKSAKEDKVANDHLHAKISKLEEFLQKKNEQISDLEQNKNELNSTISTARAYSERDLSVKQEIIDNLSSNASQEMQILKKSYEEKILELETKIAFDAVEHAKEISTREDLLKDTSSLMRKRQEEDAKYFQAESKRLKLAAAEQEKRHSENVKEIENKYIEALEHEGKKQSLLEGKYQALNEELNSKQELLESQKLSTIEKITECNVLKANISTQMDKYVELEKSFYDKSAKLMRTEMLTEQLEGKLMKKNMEYEELDGNYNQLNFDHISLNADYRDLQEKLVEAKGAISEQTQIITNLNKTKEELEFCQSSNEKEIIDLKVQMQDLIVSSANKLASSLATLKAELESKNQLTLMEATETLINKYEKEIAEKLKIIDELKNTIISLKERHDQKFGDLKEELDTIKKKYHEKVKEMDKEIVQLNGQVDTLSNNLKECHTDNTRLKINLEKARSEAEQMELDRSHLYQKMVSIDEQIRTELDAKFRQDMLLAQEEWRIKHEQVILQVTESMHIAQNNEKQLIISKMTDEKIKEIEIITQEYLNKMELSANEKKEIEKSLAASEDSMKVLMAKNSQMQIDHLKEMKLLQESEKSFQLQQKKKMETEFNANLTQMKVSAAISLSNLEKKHAKFVEELKVLHEGEVGELKIGHEHQIEVTKKEFEVLKNNEIEQIRVEQLYKDRKAQEEFNKRLEVRESELTIKWMENIKYIKTKNNEEFVKQQELVEKLTADLELANENYDKFQKLYESEIVTNDALKIDIKGVELSLEMLKQSSKQILKEHEESFIKKSQMEAEELNNAHLEDSQKMLQDFEKAQNFLKAQIQNQTKLLQEADLKYKNREPRQVDAKKICELEEELKVKKTKIKELKEEVQFYKLELNNREANFNKIFNKSPFVGVMPVLSKVRLEIELFTHYCIEKIAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y169</accession>
    <name>A0AAD5Y169_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tail specific protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000037">
        <property type="protein sequence ID" value="KAJ3226387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y169"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060:SF22">
        <property type="entry name" value="CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060">
        <property type="entry name" value="TAIL-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041992048" description="Tail specific protease domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="Tail specific protease" evidence="2">
        <location>
            <begin position="365"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="864" mass="94962" checksum="3A03B1CBCD460073" modified="2024-05-29" version="1">MLFNLATSATILLATLVNAQNAPAPVYEFKVLKDHLSSALRVTTSATILLATLVNAQNAPAPVYEFKVLKDHLSSALRFPDYTAKQRVFLADQVNKMISVYVNHESKIKNYGINSRERFADILSRAANMTNADLQNELVNTANSLRDGHTGVMYPAPHSCFAVTFPVSFQLVEFNGAADPKNPIVAVSSYVSFPEAKAIYGEELKKVKLGHILVSINGLTPLQLFEKYAHRSRGANFYGGMKAVLNNFFGLRGGRLFPIQLEKDETSVTYVFKERPDSKNTYTVSFDLVSRKTIKCVADFESTGGVSNLANEPEGQVKPPKYVIDENLNFQEFTDAFNLDNVPYIFDPETKNVLGYTIYKYLGTKLGIIRLTSFTIDGQTAEFAVEKIRKLLLNELKDTDCLLWDLRSNGGGWVQLADSIPQFFKADFTPNSRRFIMSPVNNNIMKSGAEGAEATAAYFSTPPGSFYSNFYSITSKPVANFYGNVYLKPVATLNDGNCFSACETVTANLQDSGSIKKVFGTDLQTGGGGASISYHKAHFCKYDPIDFQPLPGGQDMALGYRGSVRNGVNLGTLIEDNGVRADELLRPTLSDVFNVNNRSSIFDRIAHQLRAIGQADGSFWTKFHSEPNFSADANLGVPFTFSTTSTYINKLELHLNGKVVDSKEIGLRKTEQQVDLVTPIPTQLGTEHYTIVGYTANRVVLKTERYLRYIPNASKFASLQPGASLNWDFKFEREYVALFNIAGTAAKDGWNLKDGKLVIGDGLTYGDNVTSKVSFFVTLNGGKPSITLSFDSFSEQDYDYVIVSFRPFGGEEKELLKVSGEQHINTTLELPATTGSGELSLTFASDGGSAENGGIKLNSLSLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y333</accession>
    <name>A0AAD5Y333_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tubulin polyglutamylase ttll6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TTLL6_1</name>
        <name evidence="4" type="ORF">HK099_004078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y333"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF147">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="149" mass="17362" checksum="D17557AEE2DF117E" modified="2024-05-29" version="1">MSENNTAMITYKTAKKRKQQVINTELCKYEIIDESSNEVGLKVTKTGDLKWSIFWIDTGVSIERILEMEPIQKINHFPGMQEICRKNYLARNLSRLNRMFPKDYNFFPKTYILRDFKDLSDFKVASSSVRSNAFIAKPERGCQGMGFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3F6</accession>
    <name>A0AAD5Y3F6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001422</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000014">
        <property type="protein sequence ID" value="KAJ3227573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3F6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052234">
        <property type="entry name" value="U5_snRNP_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006:SF1">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="21"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="63"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="105"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="190"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="693" mass="80488" checksum="0992E218D7BD9E08" modified="2024-05-29" version="1">MDLSCRSPKNLKPKVDPIILLSGHESEIYTVRFSPNGNYLASAGMDRNVLFWNVKNNTNFSMIKAHKNAILDLTWSRDGENIFTASADKTIGIWNVENGVKERGLKGHTNHVNAVTVSKRGHELLASSSNDQYLKVWDFRKEKNAIKNFKGKYQSLTNDWSNDSGLLFEAGIENVINSWCMRTNKILYRLEGHEDTITGIKVSPDGQYLISNSMDNTVRMWDIKPFSVSGGSRMIKKFEGFLLIYELLKFFKGAPHGFEKNLIKPCWSNDGDFIAVGSGDRSVVVWETLTRRIVYKLPGHKGCVNQVDWHPTEPIIASCSNDKTLFLVTEKRIIKNQYKFQPTNKYLFDKLFANVLKPTKLEPFFFEMKGDPNKFDITVTTMITVDKFDVLLNSMSTFDGYFSVVLHLLDDENLIDRLESLKDFLKLNLKLLESKADIHLIIDKFPRQLNYLRNVARFFSRSELILPLDVDFIVNLNFSEHIKKNEYVYNKLKLGDSVFILPAFEYTKGNIKKNVDLFPKNKEEVKKLGKKLQIFHGSRNAGHLSTNYPQWMKSMTAYKIKPTSMAYEPYAVFNKNNVPWSDERFTGYGNNKAAWWYEIYLSGLEFHVLPEDFVIHLDHSYNEKARKEERDRNKNLFQNYLTELCDRYKVKFKIFGVDLIRRGCGDEKEKKRTLKNKFNFSKVYNYLIGEERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y403</accession>
    <name>A0AAD5Y403_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nephrocystin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NPHP4</name>
        <name evidence="7" type="ORF">HK099_000066</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904491">
        <property type="term" value="P:protein localization to ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058687">
        <property type="entry name" value="Ig_NPHP4_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058688">
        <property type="entry name" value="Ig_NPHP4_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058686">
        <property type="entry name" value="Ig_NPHP4_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058685">
        <property type="entry name" value="Ig_NPHP4_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029775">
        <property type="entry name" value="NPHP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058765">
        <property type="entry name" value="NPHP4_C2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31043">
        <property type="entry name" value="NEPHROCYSTIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31043:SF3">
        <property type="entry name" value="NEPHROCYSTIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26015">
        <property type="entry name" value="Ig_NPH4_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26190">
        <property type="entry name" value="Ig_NPHP4_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26189">
        <property type="entry name" value="Ig_NPHP4_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26187">
        <property type="entry name" value="Ig_NPHP4_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26186">
        <property type="entry name" value="NPHP4_C2_3rd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NPHP4 C2-like" evidence="3">
        <location>
            <begin position="767"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="domain" description="NPHP4 C2-like" evidence="3">
        <location>
            <begin position="894"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="NPHP4 Ig-like" evidence="6">
        <location>
            <begin position="1182"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="domain" description="NPHP4 Ig-like" evidence="5">
        <location>
            <begin position="1337"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="domain" description="NPHP4 Ig-like" evidence="2">
        <location>
            <begin position="1450"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="domain" description="NPHP4 Ig-like" evidence="4">
        <location>
            <begin position="1540"/>
            <end position="1631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1632" mass="186177" checksum="98FB3F130857D2F5" modified="2024-05-29" version="1">MNDSDAIWKEIFKNECQLTNTRKFEPLGSVVNHRRQSSSPQRPLTQYQSVNNVKCPYELKLEKIEHFPLPSLLTDQKISTMKDLRSQFRISWFDVERASFFGKTWICPVELPLLKEKSEQRFSTASTESLRRESIAKISQKESTPRESTASAGCSEAMDVLFPLRIKNKIKKNNVPLKGSKRISKSKNKRIMSESSILSDSLDSKGGEEDISEEDSFVDSNDDESCHNSEDDEDEDEEEEVSEEQSTEGEEELVKERKDSVTEISNFGKYVSGHKVTAKLRDQAAILHTTSSSPYIIIVIEVVIVSINENFQKELISAGWTFFHPFNLEKNGLDVTSVWNDDSSDNEDFEKTKTLQIFQGTPRVLPFVAPLLMASNQGFPALHPIPGALLNLKFFPRIDLRSVCYLWPETVFVGVGNYIPGLRLETTNDIRHVHMIRSTVSKISISLYPTIRQFEEPLLTKVAKLYYQAHPDSIKLDLDGKPPAAEIIERKIHVGVHNGLNFVHNPFTTTLQPNFDDEIGDGFDLNFDGHLELSKINTDEKGLVVVFCIEYKVRVQKNEPCSPKKTGFSAIFGNKSNDLDMKVVDIDRDVCIGWGFWSPSNGYDTELISVPMKFDSLSPNISGSVVYTPPCTYEDDNDDEEKSLLEFDEYGRPCATKSMPVIISFEFTDNALESGRCSPVLDRALNLTEKSRNLPEQPFPVETVDEALSPMFSEDEEVPEEITPKVEEIEIDEEIKPLPISHDSFGISAKRLSFSKPKLPLSRHERARLVTAGFEEVRDAQGHVVPSVSATDRDSLLIDYELERKDNLKVNSISFLLMGITLKPDIKTIGYPTSVYFTFQFFTFPYVTTSRMDVFTGALPAKSRSEKSKLTRLKNEEQSVNKHSRILSNKPKIVGNSEHMVEEEMLWPGILYDVKDEELDYNCAPGLKISFEIDANDSEIVDYLNENYLNIEVWDGDSMMYLGSSLLQLKTALRQGKPGVSYEEDIEIVMEEISEEHRGRIANSTSHTSGINLLAAGPPASTNLTPSVCGKLHLRVSNIGLLENKWNEKSFVKTADAVIVYDYHYSLKNKPLTFSFPKRMPDVDVELFELLSKTYQKRISERKEESTTVNVNSAVQRKLDRIKRLKDKENLSYMIGDFNKRPIHMYQMTRQERQKDLQSIDIFRERKKIFAVQNLLREQITTKCTITPSFGKACYFEFFFTNPQSKEQNFEIVWDDAELRLVVDAGEWKYLRRIHGVRIGVEEKLITLNPNGNAVLYMMPNETLAIPFVYQSFLSGYNSYGILDEDLIRMQQVNSIPESSIQGRTINVSFINNKKIPVAMLDIKLNPKNYYVSRSLRLFRAENENVRRTLRFSDLPPKQKKVKGEGNSTIFDSANPHKKYLRCNKEDVVCNITEGQNNLKEVSIKFRVAAAPETQAIYYLVYDDPYHTSLSEIWRILVHSLHRIDVNCVMGQTNATNLVLRGSSFTRTVQCYTDHTSELMVMTPSPFLLTANNLNELSMIIRPKNIDTSEMMLNIVDVNQRCIVSSWNIVLHCSPPIVTKSFDISVPRGKLVNKRVSYKNPYSLKKTFYLKTNHAHLLQFKDEMLDMGPGETQYIGLKFTPCTNLPSVSMLIFLNDETDKIEECLSVKVSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT75</accession>
    <name>A0AAD5TT75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001881">
        <property type="protein sequence ID" value="KAJ3200546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT75"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="410" mass="48697" checksum="A788E7EAAE72159C" modified="2024-05-29" version="1" fragment="single">KDLEDENREILSKFNRVKDLEVENRDLLRKLNRAQDFKEENKNLLLKLDRAQEFEVENRELLRKLNRVQDLEEENRILLLKLNRTQAIEVENKELLIKLNRVQDLEEENRILLLKLNRTQKLENENGILLLRIKEFEEDSMDDLNHAAEMKESKKRVITKENEEFSNITLVNDSSPFQSNDDLSSLSDLSEPNTIDIEENFISDPAPNSTSCEEMSYGIENKETFISLKDNLIEYYVQAVIQQFPQYFQELKTNQSYYLDNQIKLKYFISKLTSIWSTTNLTSLIKSLYFLKKILLTKKHFLCTLETVDDVFLTVLILFMMAQKSLNDDIFDISNFCDFASHFFVISLTDFKKKEWEFLQLLNFEIEILDNWEKFCGGLEVEIGFYFKKFSFNEPIFNFNSKPLTKEIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTP2</accession>
    <name>A0AAD5TTP2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001699</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001505">
        <property type="protein sequence ID" value="KAJ3202897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTP2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="53" mass="6169" checksum="423610FC23B3639A" modified="2024-05-29" version="1" fragment="single">MGFMLDPIIDDFFSDLRIFPFSSFQTENPKTNRLLTTHKNSSFGRLDVIETNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTV9</accession>
    <name>A0AAD5TTV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bardet-Biedl syndrome 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BBS1</name>
        <name evidence="2" type="ORF">HK099_001232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001327">
        <property type="protein sequence ID" value="KAJ3204203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTV9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034464">
        <property type="term" value="C:BBSome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005113">
        <property type="term" value="F:patched binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005119">
        <property type="term" value="F:smoothened binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028784">
        <property type="entry name" value="BBS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032728">
        <property type="entry name" value="BBS1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20870">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20870:SF0">
        <property type="entry name" value="BARDET-BIEDL SYNDROME 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14779">
        <property type="entry name" value="BBS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bardet-Biedl syndrome 1 N-terminal" evidence="1">
        <location>
            <begin position="31"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="599" mass="69165" checksum="2F1C91F631F80FA5" modified="2024-05-29" version="1" fragment="single">KCDVSLTNVFQTAFALSNSTGVKSDSDLFAAQDSELFIFKGLSLLQKISLRSDPSSVLQLFFRDLEKVKEPTSVVAAAVEDEIQIYLKNEIVKNIKLPKIRVFSSLETEYWKNFTHNLINKSDFSETVNSLYTNFYNNLNEVYKKNLVALSYVSINFLNLQNDIEKQTSFVKNLTINWDDEKNIQITCMNTLKRSSTDIDAEDCLVVGVEEKFIYVLIPPAFKIQKFQVFSPVALISCYGVFENDYKITFSCRDNCVYVFKNGQENMKKLVVLDFPCKSLLAYKDYVLFSTFQQQVICTNFEGLQQFQLSFECEVLVLERIELKETNFSGFILSLENKEVRIYNGQYLLHTLVNTEPIVNLKFGYFGREANALVTIDAKGILEVKTLKRNATFNTNKEEGQMGIPSGTQNIVKVRQHSSFYHESIEYEKRFCKVKILSEIYADYQENFEKMQIYNAQYYKRYLKNLNANLNENLKLSEVNKNEQSAIPENAEKNFHMKEKNKILSNSIKAIPNPPKEEASELIENNCIQLPEQLSLEINLQNCINIEQRVTRINNTYLIGLLITSKVSLRNGIHIVLKSKKNYKIFKSIITVRIFDNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU38</accession>
    <name>A0AAD5TU38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001473">
        <property type="protein sequence ID" value="KAJ3203125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU38"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="26747" checksum="D54D8744984312A0" modified="2024-05-29" version="1" fragment="single">NVMINESFEGLLKILNNYGYFLPKESINESKRISFELTIGPKQIIHSLIKHQNLNVKIKHHTLIYECKVSKEPKYILSDCRIRKADVSDIELISFWFFSFSAEALNEHDQSEYEKLKPTYLKYSRDFINKEIMYIFEIKDVDKYVPVSMAAKKRKLKNFVVISFVYTPPELRGKSYASNGVFLLVNDCLADGYKCCLFADKFFPTSNKIYQDIGFVEVNEMVEYDILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUA9</accession>
    <name>A0AAD5TUA9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SSU72</name>
        <name evidence="13" type="ORF">HK099_001056</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SSU72 phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010001275">
        <property type="protein sequence ID" value="KAJ3204680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000039">
        <property type="entry name" value="RNA polymerase II subunit A C-terminal domain phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006811">
        <property type="entry name" value="RNA_pol_II_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054517">
        <property type="entry name" value="SPEF2_D5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052634">
        <property type="entry name" value="Sperm_flagellar-bone_growth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14919">
        <property type="entry name" value="KPL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14919:SF0">
        <property type="entry name" value="SPERM FLAGELLAR PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22946">
        <property type="entry name" value="SPEF2_D5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04722">
        <property type="entry name" value="Ssu72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPC1/SPEF2" evidence="12">
        <location>
            <begin position="469"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="768"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="866"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="952"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="284"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="772"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="873"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3204680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="975" mass="112241" checksum="BBC3F5218DB1991E" modified="2024-05-29" version="1" fragment="single">MNAVSNFRLAVICASNQNRSMDAHCKLLENGFECSSFGTGSQVRMPGPTIDKPNNYDFGTPYEYMYNDLQKKDKNLYTQNGLLKMLDRNRKIKTAPERFQDNHDIFDILITCEERCFDSVLDELANRGGNLNIPVCVINVEIKDNHEDAFIAVLPVLPKFQFNNPSKKEFNEQQHRYFSELLRSKLKRGDTINITKTDDNKKFNISEKPNELKKKKNFNIKQLKTINQPEPFFVDNSELNTFIPNKKREIPLWDDATTLQSLTDSTNSAKFSFSSDFNGTNNFKEKLKADKEKLLQKKNLEKINNFFDEVNDFESKLNSIKKTKAMLTRKKSNNNKEFLLNPSIEDANNASKKEDEEIDDTKFQETNCFNVEKDEEEKDESDEIKRFLASKAGLDSISHLKTIRKNAPSSAETKSLLKKQLGNIRIKKIEEISARNDREQKRRKLILEKKKQEEMDKVRVDELMIERIMTLSKQEKRIVEQLSQVRHEKDLMRENRNFREVQYNERRKRDFEEAIEREHDLFSKHQEEYVEKTQLQLFQHQEILDQKALEKHTENVFICEKLLDQIINLAFKVSEYGELNDKAELPKKLLRQWKTLFLHDKPVDGKFGVDIDQDQIGAENMQNKESTTISEVEIVNENEDDESTLQQSQKQISKLDKTSIELLDEEEFRDYLNGEGDWGFQNDISEKMKSQITPLATLVDILFDLTAIPEPVIDKKHFANIPIKLAIIGKPFSGKTVISKMLAEQYGLHIISVEDLITSAINEANKTEQESLNRSNFQLPKTPSAGKKGFSKAQIGAKIQLSMMEGKSPEDSHLVSLVADAMQNLPKSESEKFSGCILLNFPRNRLQAQLLEKELSGYEDPKPIKLGHLKRGLNTTKDNSVSPFSGKGEAEVEQNRKRSMIAPVENKTENKRTICQSGIDMVILLDVDNETAIKRSAGRRLDSITNEEYHLEFNPPPTEAPGLNERLSGVVDDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUP7</accession>
    <name>A0AAD5TUP7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF885 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001110">
        <property type="protein sequence ID" value="KAJ3206638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUP7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361:SF2">
        <property type="entry name" value="DUF885 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="GLR0591 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3206638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="65501" checksum="D5703E4DA757E0C0" modified="2024-05-29" version="1">MGIFSCLKSSEEAEVLKKQSAPAQSALSSSELLINYQDEFVDIIVRTAPLYGPVFNITKYADKLFEFSAAYATFKMERMTKLKNNIQNLNQSTLSLSEIADLEFLKDGETCYDFEIPISHLGLLGQLVMSFQSYQAFETLEDINNYKTRLSKIAEMFDEIIVAYRVGIKKKITLPKESIDIMISQCDAAITDDYANSPYNMNKEKILQITGDSQFLISTIKDNVVPSFKKLKSFLQDEYIHHARSSSGIYDLANSNRVYTDLIYIYTSVHYTPEEIHQMGLNEVDRIWKLMVKTQEQIFPGSSVEEFRLSLKDKSKYPSLYFEKDEDIIQSYKDLLNEIDTKTPKYFRTFPKFRQCQIEAVPKAMEKGTPIAFYRPGTAQKSGIFMANCLLHKESPAIMKTSITLHEANPGHHHQVSLTLEDESKHVIKKMVKVPAFVEGYGLYCEYLGEDGRLEHEMFRALRLVVDTGLHAKGWTVEESVKFMMKYVSMPETKILNDVKRYCIMPAQAVTYKIGEIKIKEIRKFAEEQLDDKFDIIEFHETLLSFGNMSLNGLEKLMKKWVADKKKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUU6</accession>
    <name>A0AAD5TUU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tetratricopeptide SHNi-TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000582</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001138">
        <property type="protein sequence ID" value="KAJ3206232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUU6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051730">
        <property type="entry name" value="NASP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019544">
        <property type="entry name" value="Tetratricopeptide_SHNi-TPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081:SF1">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10516">
        <property type="entry name" value="SHNi-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide SHNi-TPR" evidence="9">
        <location>
            <begin position="144"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3206232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="349" mass="40535" checksum="125EA787B896F116" modified="2024-05-29" version="1">MEEPLIDNELLMETGKKAFREEDYDLAQDLKLISVSNYGENSSESIQAHFHYGITLLQKAIQKSELLGGNEDNIEAIKVEEEPVVHKNNLFFEEDSVNQHEAENGEDEEVEEEEDDLQLAWIILEKLRCILMDKQEEKMELLLADVYLNLGKISMENETWDQSISDFENALNLKSKTLKEYHRDFSELNYLLGLSYEFKFEFEKSLEYFKKSVNVLELKLEYLGGSSEKDKKGKNSLKAGESVGEKEEIEELLIDLGLKLDDLKFKIKEKKEKEELLNNSNVKEEAEKDFLDIAKQKEDVKINDLNSFVKRKIKKKLEETLIEQSKTCEENSAIQGEDSSNSHKKRKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUW3</accession>
    <name>A0AAD5TUW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">THIF-type NAD/FAD binding fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000269</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001055">
        <property type="protein sequence ID" value="KAJ3207423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061503">
        <property type="term" value="F:tRNA threonylcarbamoyladenosine dehydratase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061504">
        <property type="term" value="P:cyclic threonylcarbamoyladenosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00755">
        <property type="entry name" value="YgdL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000449">
        <property type="entry name" value="Ubiquitin-activating enzyme (E1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="102"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3207423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="459" mass="52291" checksum="C1EE8F5F1892CFE3" modified="2024-05-29" version="1">MEKFSSINLKLLLKKETLIPVVVSSLSTALVFFAWQSFTQKKKIKKLKSDLNLQTNSLSLRDHHFDETTLLEETEHQLAKKNNQFLKDDPDLKEHLTREQLARNYAFLGEEGMKNIRKSFVIVVGLGGVGGHAAHLLLRSGVEHLRIIDFDQVSLSSLNRHAVATQADVGTSKSICLKKHFSEIMPHAKVDAVVDLFTIENAEKLLQGKPDYVLDCIDNLNTKIDLIKYCVDNKIKVISSMGSGAKADPSRIQLGDISDTSECPLAKATRRGLRRVGIDHGVTVVFSLEKPHSVSLLPLEEEKVEEANEFSALPNFRSRILPVLGTIPAIFGCSMASFAAKLRDGLYERLHRDLFQKEKDHFKDTRKLKLNKCDVGFIFEEIWRGRSAVSGDMDKLCIVRWNKNLQADYGNVICLTRKEAIKHFELDFEDIEHYYDKKVLNYINDRFKLEEFWNKSRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVB9</accession>
    <name>A0AAD5TVB9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001087">
        <property type="protein sequence ID" value="KAJ3206981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVB9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3206981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="325" mass="36666" checksum="4BC2AB72542E10C1" modified="2024-05-29" version="1" fragment="single">KKNNVLVINAKFLTFDETILSTEFNFNSKELEESKNSTLSKRGDAAGELSVHRNLNNLRIVETKDFPECKECSVLLKNLAINYDFRWHVSGYVGRYVTLEIYGGGDSNIDLEFAFTSDLAEWKSDSIKLFQMALGPAVFVPGVLKLGFFFKMEIKVAIALKGKIKLTTGFDVTLSPLQYRWDSRAGSSSQGKVNTLWRHEISHYHGTKIALTAELTPKLELTPFLGFAVAFGGKDVDLGIGFKNVFEFPLILTLFGENCDLKFEVVYKPDLIARTYDTEHTLLRLPKYTLFSKCIWKRMSEPSGPNGPDPGVIDPQPRSVQPWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVF7</accession>
    <name>A0AAD5TVF7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000337</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001075">
        <property type="protein sequence ID" value="KAJ3207163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVF7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="35"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3207163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="439" mass="47212" checksum="EA8E277E89205E71" modified="2024-05-29" version="1">MEDTNTKLTENKSEEQLIEIQNDNEISKLQDSPRAWSVVAGSFLIHFFVLGLLYSFGIYQQYFLSDLPHLGNSAGIAIIGSLALGTLSLFGLVSGRLADRIGYKTTILIGGFIIFVSLILASFATELWHYVLTQGFLFGFGCSLSYFPAVSAPSYWFTKQRGLATGIAVSGSGIGGFSFSLIIQKLLDAFGIQWTLRITGLILLVAISGSAMLISLPAFKGKSRVSPPFPKQLLKDPVFIFLFLMALIGSFGYMVPVIFVPRYATEHLNLTSSQGALAVSLFNAASTVGRIFAGFFADRFFGRLNSFIGSFLTSGIAVVLLWSLSSSFEILILFNVVNGFLAGGIISLLPVVISDIFGLQALASIIGLFYMSSFVGNFAGSPLAGVIIELSTNSVGKINWIPAIIYSGGLEIFSSIFGFGAIILLKRKNKAVTTSTANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVN0</accession>
    <name>A0AAD5TVN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA stability protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the endosulfine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001023">
        <property type="protein sequence ID" value="KAJ3207908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVN0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006760">
        <property type="entry name" value="Endosulphine"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04667">
        <property type="entry name" value="Endosulfine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3207908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="115" mass="12630" checksum="60CCA9A9D118729E" modified="2024-05-29" version="1">MSSKAALSPADIEKLTDEQRAFYQKWGKLPPAKKDVLSARMKGSDRKFFDSGDYAMSQAGKASSKDIGSNHPTPEQIPHSHPTNKKNGEISNSPAKESSLIHEANFNNVSVERET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWM8</accession>
    <name>A0AAD5TWM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007614</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000752">
        <property type="protein sequence ID" value="KAJ3213045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="43"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="419"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3213045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="522" mass="59553" checksum="581D0ED945FAE223" modified="2024-05-29" version="1" fragment="single">MPLLFHSPASENFLTDFIENILTPEQQQNLNSSSSNVTSGTKKNVRKLQPKLDVLETEREYVVQVDLPGMQKNEIELSMSDNNILIIKGERKSHLERKETDKDHLGERSFGVFERRLQLPKNVNFEDVEATLELGVLTLKYVKKPKVSKQLEWKDILALQQTCKLFRSSILFNSKQAVTLLKDSTINNMFKKRICDSLNPYSIKLPLTSEFLHLCCTVGSKELVRYLIFKKVPKWNQVFTRWWQTNPDDRTEVEPSLLETACKYADYEVVKMLLIAGTEATNETIMKASENGSYEIVKLLLQDGQPNPSVFDNYCVKYATRNRHYKVMELLFSDERVDPTSNHNWAMKWACTFGYAELVRFLLSHPKVNPSAEYNEAVNLALDNHKDDIVEMLLADERVASFDAVEVEAAGPSNIQDASSTDSDSSGSTEEVMPLLNNESMEGQRNVSENNENHTMEGNADINFLQVDFGPEFNMEGFEVGNAPLIEETTDNRQNLGNDVARNDDVQEIIEVIEEIEIIEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWR1</accession>
    <name>A0AAD5TWR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_007767</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-13 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000787">
        <property type="protein sequence ID" value="KAJ3212280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWR1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01367">
        <property type="entry name" value="KISc_KIF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000012">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF8">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="12">
        <location>
            <begin position="196"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="570"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="580"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="290"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3212280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="740" mass="84263" checksum="CB1E21B6EBFF70FA" modified="2024-05-29" version="1" fragment="single">MFFEFENENKYEFENLEKIASPPSSFIQKSLLRQEKLKQKEEERKKQTGLNNSSSNNILSASEFKKISISKSPKTTQLSFKSVPTNTNKYTPNYSQQVAELKPDKKKIINFGGVSSASSPSKTLLKIQKLEEARKFRRLNQNKEKSKFVGLNQSEIEYKQIEDLLFKVKKDCDANYFKNSVDDSSAYNEGSSKGSGIVVCVRIRPLNEKETLSQNFDIIQASAGKFPNARIFLHLPKIKLNLEKTIETNKFNFDQIYTKNESNLDIYNGCVKDLVDTMFEGGKVLLFAYGQTGSGKTHTIFGDDFNPGIYLLACKEIIKKNAKMQLLKVKFFEIYSSKIFDLFQERKKLELLEDSKGNSIVFGLTEVTVKNFKEFKNLVEIGRKSRTTGSTEANSQSSRSHAVFQISLVEECTNEVKGQFSFCDLAGSEKGSETGNYTSKKSRIEGAEINKSLLALKECIRALYKEKNSSSNIAEGSHIPFRGSKLTQILKDSFIGKKSKTVMIATVGPGSTYAEHTLNTLRYADRVKELKITKKVKQTNQNYKISTDDAEEEDHNYEDESEEYFIEQEDCESELNQPEDSSEELLSDEESSGVEDDVDKRISGLLSENKNEKFLKKLNSVKRCNLQKTNLQDLIKNIKEKDDKLDVEEVSFEIVENEKLKGKGNSELTNYEEEDLVDNEVWVQGKSLIQEHSESVDGLLEVLRIEEELLKKLLNGEINLPLYKKELTTLLKERILNSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX07</accession>
    <name>A0AAD5TX07_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001177">
        <property type="protein sequence ID" value="KAJ3205772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX07"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="403" mass="46702" checksum="CB4972688BE785F3" modified="2024-05-29" version="1" fragment="single">KSKLNLLGKFIVAANLINLYERNLGQPDKYGFNAFDFNRLILEVSSLIFYFTLAIITTESSKKTIYELNEKINKYLEKKNDYEAEDNKKINHYLGSGDEQEEGYLSTPFSDILIYIWRMLHLPLHAMLTVTLVAIQIFLEKLYIVSRFNSTGLGTLIPPSTNIPFWPAVSVNLRVQNENATVLEDNVFLQSNSQKSMENSSHILLNLVKNSYTSLLTQTNPIAGRSSSFGEHISLINLLIFSLSLTIFFSLVILIFNFYFEFKLNFHNAINASLYQLKDLKFKLITNLILKVTFRILSIVMINLILTFNVKFNLQLTDLQIYYTLFCCIVLNQLILENLNLFYFYFKSMYLNRSFNSKKNQKNKDIGERCSPEDVTNSTVNDYRNNNEILNTREIFDDVGYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX47</accession>
    <name>A0AAD5TX47_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ELP4</name>
        <name evidence="9" type="ORF">HK099_007099</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ELP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000661">
        <property type="protein sequence ID" value="KAJ3213969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX47"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19494">
        <property type="entry name" value="Elp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008728">
        <property type="entry name" value="Elongator_complex_protein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12896:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12896">
        <property type="entry name" value="PAX6 NEIGHBOR PROTEIN PAXNEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05625">
        <property type="entry name" value="PAXNEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3213969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="425" mass="47296" checksum="09B550772B06835C" modified="2024-05-29" version="1">MSFTKKNQSSNNFIGTITSSHNSLTLCSSGCGDLDLVLGGGIPLGSILLIKEDKSTKYANLLLKLFSSQTLDSNHSLLFSGSEITSTVENLPLKVIKSSATSTNLKDDDGEILDLSNFTSKRTMGLVRNRDPVVENDKMKIAWRYQNLGKFETDLSGRSGLNHTFKNASLNAVPYLSIFDITKSIEKKKLGELVSNGNLHVFSIEDFNNTDDCYEKLFQKIENVVKEGNFSLKAPPVNGVKRILKVVIQSIGTPFWNPSNEQSHFKFLYKLKLLLSQVAACCMISIPAYLYNDHYQIKSQSKIRSIERFCDAVLELESFEGSPRELHPAYTTSTPLQPAYHGLLHPLKLFNQNTLIPATLRNLDHSQLRSLAFRVRRKKFTIETFHLPPEEGEIENDLKIKSSGGDLGFTGGCGAISDGKSNLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXD6</accession>
    <name>A0AAD5TXD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UAA transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DRP1</name>
        <name evidence="7" type="ORF">HK099_006895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000625">
        <property type="protein sequence ID" value="KAJ3214395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXD6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="140"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3214395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="345" mass="38605" checksum="7AB6BE6103052ED1" modified="2024-05-29" version="1">MVIFGVVLATVGELEFTTLGFILTFLGVVLSSLKGMATNLLLIGNLKLHPFDLLRKMAVLSFFQCLVIAFWCGEVTLFMEQLEHNRAEQSAMMGHVIQEISAGGNWVLKPANGKNEWVFVPEEGAGQSKLMATGYSAYFDKNTKLYLALLVNGLLAFLLNFVSFTANKKTSALSMTVAGNVKQAMSIVLSVVLFGYVVTSINGFDFLLQKSKPVQAIEASSKEWEYDSHQTKKSLNQSALTTPQTLHYNDYYETLHEIAKNKVLHPFYINKNLQCNPKLLLQQDSVNAITSEIEFKRNDSAYMDDYSVNNCSCSDALIVTKKDINKHLKISDEDSLKVKRTRSMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXL3</accession>
    <name>A0AAD5TXL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nuclear control of ATPase protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NCA2</name>
        <name evidence="6" type="ORF">HK099_007076</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000659">
        <property type="protein sequence ID" value="KAJ3213993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013946">
        <property type="entry name" value="NCA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234:SF1">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08637">
        <property type="entry name" value="NCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3213993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="870" mass="99869" checksum="650F8E36A45C1F12" modified="2024-05-29" version="1" fragment="single">MDSEFANEQYKKLLCQIDRTFSDFNINSLEVEGAIIGQELSLFSVDTNPRDLLLVEDVNVAASSTKLPTLHQIEKSLNKTAAILNEKAALSEFECYEILLYFAKVTTGLHSRLTISLMNSSVEFPNSLSFLSEAQTSYVKLSLHFLQTLPRRLKYLWHKANSHKSYNGILSLLNFKKNEIYRRSSFSLFSPKLKSKNIFNTSFIKQVRQHNVFFTTLELLKSETKFNSSVLYFTKLFEAISLGILKQNGIGFTHEKGSKAEIGECGRNISNSLNLMNHILERREELTEFVLKKDSAFTVKEVDGELEAMTDIISLNENKSYLNLKEIQNFSHLLKKLTKKLKNYDKTTHVIHYTFGKPDALELYWPHITVGVLLTWFGVREFKIYRNSLKELAVELIKTTKTFVSDWVIEPLIKIYETIRHKEDRLALLGTESLNSDIESLERMVIDFSKSNGIVSDAELNVISEKVVKGDLTPILKAYEREIKNPLINVVKGNLVQALLIQVQKLKVDGEIAMSALDKLLKSNELNFAFLAALPIFSLTGYMCKKAINFFSAKRFLTKDIISKRIKSSLREVEKILSKTKKGKQINFKEEGLLLSQMYLLRKYLKEVPVTDQFSFLEDLRDLESDNVPARKSSLNLSVVSCKKTESEDRNELIIKRIRALGYKVQGGFVDYSYEKIQTKFSNLNVSRACKDAERELLLFDYKHATRNDAFSDTSSKINMNTISSNSIAASNNSSLRDLGSIVRSRRGSYLKGSLNHIEALNAKSKRESLGEEDIFKFPRMNLTFLTEFPISKSSRQNIVMEKKKLRLLKILRAIKNAFHFIKYMARNLGFNRIERGWEYQTITENKLTTRNETTSSYISRKDQYFNGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXP4</accession>
    <name>A0AAD5TXP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Condensin complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_006783</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the CND2 (condensin subunit 2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000605">
        <property type="protein sequence ID" value="KAJ3214615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXP4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022816">
        <property type="entry name" value="Condensin_barren_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108:SF9">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05786">
        <property type="entry name" value="Cnd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017126">
        <property type="entry name" value="Condensin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="8 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR017126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3214615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="698" mass="79564" checksum="D989870AAD2D180D" modified="2024-05-29" version="1">MQFITPTKSSFQSSTNENTPTINTPSKLYDEDDIKRLFEECIKKSTENKINSANCFDMGLIDYFAGIDVLKDGSSINFQKASCTLDGCIKIYSLRVDSVDSEAKKLLSGLASNYDGEDQENLENDEGKPKKPRKTNTATLEKDPNLLNLKKFDLEFDVDPLFKKTSADFDEGGAKGLLLNNLSIGNKGKIIFDASNIPGNEEKEEAVISSSTAVNVAKLKAKFNDSLQNMFQKDICPSLKNFKFSSDDTPYSMFNPQKYLDSVHEMFSFNPDDDQDSTNDVHNANCDYDSDDNNFTDYNRNPGFGEPVHVNTNESNDIPGIINEIENNERNVDDDAFLEVEEALYSQNDQEMFSYFQKSVNDNWIGPEYWKPKKEIKTKEELLQNTAKPKRKKPEPINIDFDGPPVNLSELFTTSKATINLPKNKERVKSLPSEDFNFNAEKMVSLFIKPDAKILWRTKDNKLKNNRSIEANLADDDNPDVDFWAKHENDEPVFVEPELQEQNQEEIFEDEYSSDDEENIIPLPFASNEGLIKDYNISGAIDYGDQLVDEPRKTKAQYMKYARVSKKVDVKRLKDNIWKSVETAVDLPNESIKSECKFSEVVHGLQNFYSEKKIKDISVAFCFICLLHLANEEGFEIQMDEQGKGAVSNNFDISENNLDNISLFEEKSSFKINESFNKKESFYGMDELTIQFLNNPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXX0</accession>
    <name>A0AAD5TXX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000565">
        <property type="protein sequence ID" value="KAJ3215135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXX0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="80" mass="9241" checksum="8F0AF263D9846322" modified="2024-05-29" version="1" fragment="single">MTLELKEKLKEYEAQSASQNTGLKFELLADENFEKNYLFMGKIGLVQRKLLYISISNSTVKKLKSPAYVPIFKEYSSLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY95</accession>
    <name>A0AAD5TY95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006146</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000511">
        <property type="protein sequence ID" value="KAJ3215910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY95"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="59" mass="6651" checksum="A93802CB46F9D5BB" modified="2024-05-29" version="1">MSLLFKKVKLTTEEIVETEADGSIKLTATEPDLKIDDGELFKKMDNEEEEIEKCSRGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYI1</accession>
    <name>A0AAD5TYI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_007873</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000802">
        <property type="protein sequence ID" value="KAJ3211994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYI1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000014">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="574"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="615"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="699"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="803"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="263"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="575"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="893"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3211994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1156" mass="129187" checksum="8956E03596CFE617" modified="2024-05-29" version="1">MLLGVKLRVGFIALIYKKMLRLKEGGPGTTGKIVNIISNDVQRFEDLGPFLPSIFSVPVEIVVSTIFISTQIAESSLMVLVALFLYMLIQASFGRLFGRFRRITVRFRDERVRTISDMLAGILVVKLYSWEKPFTKQVEKERKSELHQIKKSSLVKSCNEAFYFSSTTLIPLFPFITFYLLGGILTPSAVFSSINVISNLKMSLSKGFAGAVQFGSEALISLERITEFLLLEEIELNAIALEKMDLTFLREKGVDTEEIICLMKNASFKWTSSIAPNEDIGQNILSDIDLTINKGKLLGVCGPVGSGKSSFASALLGEMDCTGGMYGLRKTVKDPNGETRKLKIAYCSQIPWIISGTIKDNILFSETYNEDWFKVVISACELERDIESFPEGVETLIGERGVLDDPLSAVDAKVGRNLFENCLKNLLLSSNTYGNYRKNPASVVLITHQLQYIKFCEEVLVLINGKINSIGKFEDAVNVNTTMRNFLTEGNKYEVEESDSSTAGEEELIKENPRIATNTNKTIDIEDKLNPEEKIEGKKDKDKELSKELTEAQGSVNINTYINFFKSGVHPLQFFLLVAVLICGQVSSILGDWSLSNWANESAAQQKASGNKHASIYSGLVCLTFLLSFLRSGGFFLVCLKCSRSIFLSMTKGVMRSPLYFFEVNPHGRILNRFSKDLSTVDELLPPTFFDFIQASFQIFAALVLSCVFIPPILIGIPFVIGVFFFLRKYYISSSTQIKRIESAAKSPIYANIPTTMEGLTTLRAFGAQERSITVFNNLQNKNTRFYFAFISCSRWLGLRLDWLSGVFFLMIVLLSVFLKENSKLGASSVGLVLTYALQMLGSLQWGTRQSAEVENQMVCVERMLEYTKLTPEADEETKDVVLPSNWPDKGDVKVDSLSLIYPGTTHKVLNNISIHFEAGKKIGVVGRTGAGKSSLLQALFRLVEPSEGNFIIDGINTSKIGLKDLRSRISIIPQEPFCFKGTLRFNIDPFGKYTDDELWTALEAVELKKLIEGLPQKMESPVSEGGSNWSVGERQLICLARAILRNTRLIVMDEATSNVDLNTDQLIQNAIRSKSGLFANSTVLTIAHRLNTVIDFDKIMVLDFGKVVEYDTPYQMLIKDSNDPGAWFRRMVDEMGEEAKISLLKIAKQKNDLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYJ2</accession>
    <name>A0AAD5TYJ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000796">
        <property type="protein sequence ID" value="KAJ3212079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYJ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="183"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3212079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="633" mass="70898" checksum="AEECDEF29E481971" modified="2024-05-29" version="1">MHGLSALLNPSSKDDDALTMFELGIDNERTIFLPGQSLDGQISLSLSSPVEVTLLRIRFTGFISTHNYKSESLNENNSTATLFKDLQTCVGGLTDDNPVLLEAGDYVYPFSFRFPALALPPTYDGVYGTVRYEVGAVLVRPNKFNKTASIQLSVPSTLDSGNVLYNDPVEQVVKKNVGVWWWNKGHVEVKASIPRKAFPSEDILPLTIEITNQSNSSLELSSVYLKQRSSCRTTEDSKGPRTEKIHKLNFSETYLPELKHIVRQIQFPIPETSIFSPSIKTAILEVFHILVIKVKIKSNLPSNDVYNCGLDETCNQKKIKKKRFSYFSSSNQNLSKFSDKSSINSSHGEGSQRSSSIVELQKYRANSNQHLKRSKSLNFIIGNNTNSIVEFSSFSNLKRRHSLPITKVNSLRSELNILSDANFQPENLILPRISLFEVSSINPSVITNSSNRHSHFITSSNVDVNSSTSGSHEKNSNKRNSTTIMANSNFKKLLKIERTVKLELPVIIGGFPHVLMDVQRRRSIDTLPLYFNEECDKIVSNNSNNTNYDSETTPQIFVSDENLKVEDVASVRLNTCSSEDTINANDCIPHISSSMSFTQCKTNDLAEEDFDEEIYTDALEEIPLDKCSLIEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYT1</accession>
    <name>A0AAD5TYT1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000492">
        <property type="protein sequence ID" value="KAJ3216200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYT1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="22086" checksum="5B4765EA3CE71C91" modified="2024-05-29" version="1">MQYQDKLQYTQPPSFIKNEHTEKLPTYLQILPFNIQSLLIDKPVNPTGQSSIPTSPPPPYEPLNYQNKPNYSNKFSISNLIQAPVKQKEYLNEPKLKKKEGKQEQILRCPDSKCNQFGKERKFTSHYMLKSHLAVHLEKRFSCDDCSKRFGRKHDLQRHCRNIHGKKFIDPTLKRLLVANLDETYKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYV0</accession>
    <name>A0AAD5TYV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005704</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000458">
        <property type="protein sequence ID" value="KAJ3216835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYV0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="90"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3216835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="28083" checksum="63BB88548A05FF0F" modified="2024-05-29" version="1">MLTLYTATTPNGWKVSIFLEELKSVYGLDYNVIKVDMGKFEQKEESFLKMNPNGRIPTIDDDGFFVFESAAILYYLAEKYDTKNLFFPAEFEKRVKVMELLFFQMSAQGPMQGQSNHFLRYAPEDIPYAKNRYQSETKRIYNVYERILKDQLYLAGNEYTIADMCTIGWAASATWAGVELTKDEYPNVVNWIERVRSRPAVESGLSIPTRNELIFGDWSKAESAAEAGKKMIKDQIENSSKSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYX2</accession>
    <name>A0AAD5TYX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Multidrug and toxic compound extrusion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005616</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000446">
        <property type="protein sequence ID" value="KAJ3217060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYX2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3217060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="50290" checksum="8FF66A3AB1E6BE4F" modified="2024-05-29" version="1">MAWPVSFGYFLQNSLLLATVFSMGHVGTKELAACALATMWANVSGFSLGIGMASSLDTLCSHSHTGSLDIYANGKHLQRALVVMSVISVMVSALWCFTEDLLLLAGQDAEVSRLAGIYIYYLIPSVFPYFAFECLKRYLQSQGIMSGALFCIFLGSPLNAILQYLLVWGPLNLGFIGAPLGLSITYIILPCFMVIYIRYFTKNSAWGGWDFAEAFNVFEIMELLKLGIPGVFMICTEWWAFEVIALIAGWFGEKSLAAQSIVLTTTSLAYMIPMGISIAASTRIGNALGAHCADMAKISSFSSLLLGGVIGTLSCTFFLVVKDSWGYLWTSDIEVVTLVAQILPVASVYQLSDSIAVIGAGVLRGCGHQKIGAIINLCGYYILGIPVGLLFAFTFAWKVTGLFVGVAVGLIAVSIFYACWVLKLNFEQECENLRLKLKKTNNYLVLENDEEYYNEYQACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ93</accession>
    <name>A0AAD5TZ93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001148">
        <property type="protein sequence ID" value="KAJ3206141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ93"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3206141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="113" mass="12965" checksum="5D0F4A2C2F977FA1" modified="2024-05-29" version="1" fragment="single">MSIEELDPTACTVTCEWFQHAVGSSRQKTSKSWLSLWDDYFPGGKKCQVRGCPSTYNLIGGHVVLKHQRDKTKRCYIVPICRNCNNNRSANENSEDDEIFYAKSKAKFLKINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZL7</accession>
    <name>A0AAD5TZL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000380">
        <property type="protein sequence ID" value="KAJ3218434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZL7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="209" mass="24480" checksum="5ACF946930D280CA" modified="2024-05-29" version="1">MSTTLTHKIRFDQNFPSVITSNQPFKINFEVQFPSWETTSYRHLDFSGLYQARRDIYHLFITLVDEQNNHLRHLFFKEMFCYNGNFGYSKENEDQKGQPNEFYLPSYTINPKNDKFRIKVSLVNQDKWFTSFTEVSKTFSLQVSNNPVLEDSIFRKLGDGNHSEEVSIFTSMWSCMDSAEPEMQEIVQTVRNGDVVNTSTLEFALKSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZV0</accession>
    <name>A0AAD5TZV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_007617</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000753">
        <property type="protein sequence ID" value="KAJ3213043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZV0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3213043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="178" mass="20589" checksum="63D116FCB49C967E" modified="2024-05-29" version="1" fragment="single">INDRQLKVEWAVGSRKTPYEMKRKDRKTDRSHGDNPVRLDEVLVEEVEIITERVEVETTIERVGMTIGKGEAMEEGTIEIEVGIEAEIGEEADPLEEEALSAFFIIAGLGIGMRFGVKQYQKYENYGKPKRWNVDKWDRRMMERDSRLTGNVNIQSDEVVASEKFKFNSALELERPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U051</accession>
    <name>A0AAD5U051_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000340">
        <property type="protein sequence ID" value="KAJ3219408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U051"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="54" mass="5979" checksum="A9F199069BD4509D" modified="2024-05-29" version="1" fragment="single">STELETSESDALFLFCVDYGGLVTRLVSPAIYQFPEVGIMDLINLHMLSSGLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0K6</accession>
    <name>A0AAD5U0K6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_004154</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000288">
        <property type="protein sequence ID" value="KAJ3220601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="35"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="3273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="3272"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="3276"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="3295"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="12">
        <location>
            <position position="3358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3220601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="3862" mass="436695" checksum="B8ED0CC857AA6E90" modified="2024-05-29" version="1">MKKFLKIFKKDKNSKKNISKAFESSFSNKKFFDLYDLGKTLGSGSQSTIKEAVRKSDNEKFAVKIIARNTFAGREETVKNELEKLLKAKLSHSHVINVIEIFDDGDNLYLVLQLAVGGELFEKIIQTETFTEKDAAKIIKQLLEAVDYLHQKDIFLIKITPENLIFKNSEVDSPILITDIGLCKVLSGDARKVSCGNQNYSAPEILADAEHTTAIDVWSVGVIMYILLSGYTPFSSNEKVEISQAILESRYDFSEQHWQSISLQAKELVKSLLEVDPKKRITTKVALAHDWLKIDSTTDLLPNAKNFFDAKKTFQDAVKSVTVANTFKSVGAKGNLADNKDILPTTLVPSHYVVDITPNFSAPFNFNGVVTIYLKVKETTSTVICNAKEVDVTSASIVIKDSPRKEDATDIKHDEKNEQVSLQFKEALVAGSDVVLTLKFSGTHNDQLVGFFRSPFQLGGHHILVTQFQPCCARMAFPCWDEPALKATFDVVLRVPKGFTALSNMNALESKEEENLSVVTFATTPLMSVYLLIFAAGELDYIEATANPKIPADSPPVTVRVYVSKYENVNHGAFSLELSVRSFGNLVTMEWWDDLWLNEGFATFIASLALEKFFPTWNAWNMFLTNEYSFALQLDSLLSSHPIHANVNNANEVNSIFDAITYDKASALIRMLNFALGTETFMKGIRSYLKKFIYANAKVEDLWEHLSQASGKNVSAMAHKWVYKTGYPVISIISESYDEDKKELTLELKQTRYFKNGELTDASNTIWEIPLSLITHERKDFDFTMTKANESITFSYNKGPESFFKLNHQCRGFFRVDLDIENITTLAKKNLEVSDRIGIISDCFAMAACGSTKLSDALNVVIGFKKEENVMVLREIYNQLSTLESVSYNNVTHVNALNKLMGEIFSPKVETLGWEYSDQDDNDTIVRRTLSITSCGISGVKSVVEEYLRRIKLFLSGDEKILHPNLVPTGLVMFLRHSTSPQNDFEKIFSLAKSSKSEEITIGCYRALGAINSEETLTKFFNEQILDVQQVSASQLTTVLLGITNYSPISNVSKPLLWKWLVKNWDTLYSRFINTPGAFATVVKICVRTLVGEESETLIKSWLKGDGLTDDLKLKRLEEIKLAQPDFDQSLEQVTCATSAIKKYNEDLNAWAALEISKNELREVLCSDVKPTHYVVDITPNFESFIFNGVVDIHLTINENLKEITCNANELDIQAASIIIIDFDPQKNLTQVATKIDYDKQFERVTFTFNDTISKGAKAILNLKFTGKHNDNMVGFYRSGFKKDNQQKWLLVTQFEACDCRRAFPCWDEPSLKATFDVILRVPRNMTALSNMNVIETFEENDLIVSKYAKTPIMSTYLVAFAVGELDFIEATANPQKPADAKPITVRVYTNKGESEMGRFSLEVAARTLEYFSEYFDCAYPLSKMDMISVPDFSAGAMENWGLVTYRSVILLCDEKTTSAIKQQIAYVVCHELAHQWFGNLVTMEWWDALWLNEGFATFVGWLAVDHLFPEWDIWTSFLNAETFEALELDSLRSSHPIEVTVNSPSEISQIFDAISYSKGASIIQMLSWSIGQEVFTNGVRSYLKEFSYSNAKTNDLWRHLLLASGKDVELMMENWTRKMGYPVINVISETYDEEKKEMTLHLKQNRFLSSGEEDLSEQTVWWIPLGLVTDADPDNPLDHIMTSAEQTITFAYKKTATSYWKLNYKCRSFYRVNLSFENLDLLSKSPLSIADRVGVVGDAFSMAKAGFASTSSALKLVENYTNEDEYVALTQIASNLNAVLYSWYNESSNVQSAVNALRRSIFSKKVAKVGWEYPAGEGQIASLKRTLILSAAAKAGDHSIVQEFRARIKKVLTGDQDALNFNLISPGFSIFMRTSTNPEEDFDLIFNYFKTSTVEELRLAALSSIGSTNSADILKKFLYTTALDVQVIRPQDLIYVTRGFLQNSPIPEQVRPLTWKWMIDKWDLIHERYADIMGLFGVIVQSCVSYSVGDDFAEEVQNWYTGALLSTSEEKEKRALQVAPVISSFKQSLERVYSNTKWVKASRSNILEWAQLHKSDSIVNENLREVLSDIATPTHYVVDLTPNFDTFKYKGKVTISIDLKKNTKTLTFHAIDIELISAQLINGDNLESSTNFKYDTKLQTVTVEFLNEVTVGKGYKLKLEFIGHHSDKLAGFYRSSTTVDGVKKWMLSSQHESADCRRSFPCFDEPDLFVALKATFDIILRVSKGLTALSNTAVKKQYDENDLAVFEFSTTPVISTYLVAFAVGEFHYLEAVATPKKPDNAKPITVRVYTSIYENIEQGHFSLAVAVKTLEFFSEYFDIAYPLNKLDMLGAFDFSMGGMENWGLICYRNSALLFDEINGSSSNKQNITSIVSHEIAHQWFGNLVTPKWWNDLWLKEGFANFACIFMDYLHPEWDIWTATYQFDTMDALKLDSLQSSHPIEAIVNNPLECGTIFDVISYDKGYGVLRMLHGFLGEEVFKSGIRSYLKEFSYSNAETSDLWNHMSKASGKDVAFIMSNWTKKMGYPVVTIESEFYDEEKKEMTLTLRQNQYFSTGAVEVLSPVWCIPIGIFTNTHPKPFDLIFTKEVEIFTFPYENTATSFYKLNYKSQGFFRVNIKQEPLMKISKLVASGDAELSVLDRVGLLSDSFAMGVSGYASILSALDVIKNFKNEKNPIVIEEMVNELDLLKGFWYNSSPATINGFDVLKRSILLPRFHELGWDFNKDESDLVKLNRALVIDGLAKVGEISVVEELKTRFTLYIAGDQSALPANLIAPAFSAVLRNATDSSEFDTLVKLYPLGDNEKKRHILTSLPYTNQVELLRKLLNELIFDENFCRSVYMYQAFFNITKSPAPFARDALFEMFQRKFEELNNKLSSSSSVNLRNKTFAMCLESSVGSEFLSKLQNWYQVDLEKSDSLKQLKKDIETIYLQATETVKYTSALVERENSAVENWVKKNLNDIKNSTSSSEIREVLPLAVVPSHYVVDLTANFDTFRFIGNVLINLTIKEETSRISCNAVDLKIFNAQVTINDTTTLKAEHIIQHKSSGTVTFTFKEKLPKGKASMVINFEGTHSDSMSGFYRSGFMKDGEKKWMLVSQHEACDCRKSFPCWDEPALKATFDVILRVPKGFTALSNTNVIEEFEENNLTVSKFATTPVMSTYLVAFVVGELDYVETTSKPLSPPGSKPIVVRVYTNKGESAGGVFAAGVAEKTLEFFSEYFDIAYPLPKLDMVAVPDFAAGAMENWGLVTYRTVALLYDEKKSSQIAKQRCAYIVGHELAHQWFGNLVTMKWWNDLWLNEGFATFVGWLAVDHIFPEWDIWTQFADSVTNTALNMDSLRSSHPIEVSVNKPSEILQIFDAISYMKGASVIRMLYWALGETVFKSGVRTYLREFSYSNADTSDLWRHLSVSSGKDVAELMNSWTSKIGFPMLTVLAQNYDAERKEMTLELKQGRYLSSGDWSEAEENDVHSTVWWIPLGIITSTNSEPGDLLLTTKKGSVTFPYEETENSFWKINFKTRGFYRVKLEVPYLEKLSKNINQLCLTDKCGLVADAFSAASSGQGSTVACLELIKSLKNENEHIILSTMLVNLGNVISIWDNENPAVKEKLNSLKKLLVTSKVNEVGWEFPENENQQTSFKRTLVLSAAGKAGDQSVIKEFQSRFKKFIEGDESALHPSIQGPAFSVVLRNAEGREEFDSLLKILKETSSQEKKLSILTALGATKSIELAKFILSDVLLNLDYVRTQDVYMGVAGLSRDSPISTLVKPLLWKWLTENYDLIVERFRDTMSLFGHIISFCISGQRTFNFINEVEKWSLGEDCLTEADRKKRLNGLATVDGKLKQTLEQMKVETKWLEKDRRVVEDWLLSQNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Y6</accession>
    <name>A0AAD5U0Y6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acetate--CoA ligase</fullName>
            <ecNumber evidence="2">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ACS1</name>
        <name evidence="12" type="ORF">HK099_005533</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000435">
        <property type="protein sequence ID" value="KAJ3217262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="11">
        <location>
            <begin position="33"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="9">
        <location>
            <begin position="91"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="10">
        <location>
            <begin position="520"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="707"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1541"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="996"/>
            <end position="1023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3217262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1715" mass="193253" checksum="E95453A55A613DC2" modified="2024-05-29" version="1">MKEGKNEASEKTFPVASAILNHSQKPYYDSDLYKFEYKQSIENSDEFWNNKAKELIHWHHPYRKVSSGSFKDGDVSWFHDGQLNVSYNCIDRHALVNPEKVAIIWESDEPDVSKNITYKQLLEEVSKLANVLIKYGVKKGDNVAIYMPMVPEAVYSMLACTRIGAVHSVIFAGFSSDALRDRINDASCKILITADQGRRGGKSIHLKKISDEALKQCTSIQKVIVFQRTGDKSVPFNTDTDVWMHEETAMQQPICSPELMGSEDPLFMLYTSGSTGKPKGVVHTTAGYLLGATMTVKYVFDYHEGDIFGCMADVGWITGHSYIVYGPLSLGATTVLFESIPTYPNPTIRALRRLGDEHVSSFDLSSLKVLGSVGEPIGTEAWLWYHNVVGKGKCAIVDTYWQTETGSIIVTPLPGATLTKPGSASFPFFGVELAILHPETGKELEGNDVTGVLAVKKPFPSIARTVYKNHQRYLDTYFKPYGGYYFTGDGASRDKDGYVWILGRVDDVINVSGHRLSTAEIESALVLHESCAEAAVVAIPDDISGEAIVCFCTLKVENSNEEELKKNLKQQVRSGKIMRRILRKIAAKDVDVNDSEEVLRSKLGDLSTLADPSMQVHQCTAFEAREERMTIHKEETSDDTLLDKNLLGRSTKTMNKVQTEIFSFMKLFNNDSFISDLDDKIFEKRKLIDNLIQTTSVNELNNELWGESNTTLHLASYAGDVEIIENLLTKGASTSIKNRYGLTPVDVAADEETRTVFRNFDLLKNNKNIKPKTQNQKKTISTKISNVESFLLKETKILDLTLPNKKEDLTKSTNSLDKKLMYSSLSSNPFISNDKKTLVPVNRSLKNSSFFFQNDFTKSKTVSSKSIFTKFDQNLVVENDDNLKKSKLFYNTFSSSATLTKNNAWSEKRSLDFTDPRKNIVSNFQKKKEKVGAVERDEWGYFSETLNNPKTDVKDSVLTFSCVSPAQSILDTYSGPCNGVNEDAIVEGKPLVALIKSETQNKFDTLEKKNEVVEEKKKEIQSESKYQKKYEMNELKSGGNKQQEEEKKNFIFDEIGYKASDIIKNFEKSLPTKEGGSLRNFSISKSKKTTQSILKKSTYENPEKPIWARSDVLTPSCLTKKIKNETVEFPVNALIWERTDVTKVKLIPTTAEKSTNSLDLYDQPDVKREKTIQNSFNSVKKNDEMLEFQVAVEVEVTNVDNPSSFDDLTKKYPEDLETCPQLESELKSVPITEIIEDVQKVDVSSDMNNEEEVLKSSKGSSSDSVSTLLDFTGSPNYLENQPFPQSSLTKKNIVLLDSLRQESFSSFNEIPKIGSLFDEGDYWFEKILENSTDIATECSETNNKNGPLQTSVAPPKVDILDKDEDDEGVEEDETDLKTKKNVNDSVNAYHYFPVLGGGKFQVDDCELEEPADKKFYVNNADCLEHKNNIYDFKIDLKSNDQTLENKKKSSWDSQFQKKTFITKSGIAKGHKSEDSTGIVIAQDQVIDIYYKSEGNNSLICQGIQLLEKNRFVAVNTDFTFEKFEDTTLEFEIILKEDEEFDQSQANGGTTQQKKKESSSQKNLKSKLSVKKFLVGGINKLKTNLTNLTESSSQENIVADDTSSIGSSYEDDPQQLFLSSSSKLNKLTKKNSKKKSPSQQFDDIVQKSHLRGSGKMDLNLVEKKILKDFNFEINYKNLNHSTDELNEKKVENFSSFGKINLKLIYIPYSNYIEVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Z5</accession>
    <name>A0AAD5U0Z5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase zeta catalytic subunit</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">REV3_2</name>
        <name evidence="19" type="ORF">HK099_004043</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000277">
        <property type="protein sequence ID" value="KAJ3220737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Z5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05778">
        <property type="entry name" value="DNA_polB_zeta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000002">
        <property type="entry name" value="DNA polymerase zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="18">
        <location>
            <begin position="44"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="17">
        <location>
            <begin position="720"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="16">
        <location>
            <begin position="982"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="457"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3220737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1197" mass="138777" checksum="5F41846D94236BE7" modified="2024-05-29" version="1">MSTDHYHFVKLIHIDHHQVDNLPVIRVFGVDKTGISISLHVHDCLPYIYIPYDGEIDDFSNFAFVFVETLHLALEKLKLKEHVYIKNLVLVKGYEFYGFDRNVKLFIKIYYTNPSKKFAIVNLLQRGSILDKIFKVYDATFNLVQQFMIDFNLTGMNWVKIDNYSNPLLKLTTSVEDWECSVTNLRNIDEIKQRKNGLEVYEKKWIPSLSSIWESHGFNEKKVKSQIRPLNDMNDRLLERLKLKLNASKKFNNDFMSPDRQLPVKLLEDFEGVMTLFESLLVNAKPELMEEYPNSFVREVDEVALTQVVEQYSQGFENMLDVLDAIEKEKEFENMDIPDDNERINNQYNDDDDPNYEEDFDPESSAFFDTPHSTAKASRLRNIVNTPTNIKRNLAREFSQLTPNDSENVDAISEDENVEEVANTSNDHKYFFQISQNDGADDNDDEIWVKAQKESLKRKRRTEEEMMTPLSSKRRTKEKETEITKINKRLKYENDIKQEVNEHNQSYFTKSILQLWSPLPSMIHNQEKPMPSSPSLLKNKNLEDYQHFVKPRDSNLNSKISTLTSLSGTEDSPLGNTNTAESEAQQFTDKKKLIYQYPIIPPSQLDLDNTFKDFKLPSVIYKEPHFSNPKDKVKKRIYAGKEITIPVYSNGFKLDMKNEFNYKDISDSYKGLEYWRNMNRDGVSNLQSSSYFCYGKNPPKRSEVEKWCNENVASTSQKDISQVKFPTQRNFGQKFDKVEKNLTEVASDFLTILDIEVFVPTRADLNPDPKLDKIEAVVYCFYSKNSSNEASNIKNEKKLGVITVEKLNSFNKNGLHNGYQIYQVKSEVDLLMKLIELVYELNPDIMCGYEIHNSSWGYVIERGSILDLDVLAKFSKVLVNPITKFGRAQNPFFHDTFTSLYTSGRIFINIWRLMKTQLNLSSYTLENTVFQIVHQRIPHFSFQVLTNWYNRGYIKRVQLSIQLLEETNFISQTSEFSRMYGIDFTSVITRKSQFKVESILARLARPENYFLLSPSRDDVKGMRAPECISLVMEPESDFYNSPTLVMDFASLYPSVMIAFNYCFSTCLGKVDKVGERHKFGVLDDFSIPLEVVNELIDDVIVSPNGLIFCKPHIRKGVLPRMLEELLETRVLVKDSVKNFKTDLGMKRVLDARQLGLKLIANVTYGYTAASMTGKMPCVELADAIVQSSRVILETVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1A0</accession>
    <name>A0AAD5U1A0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000355">
        <property type="protein sequence ID" value="KAJ3219047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1A0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="398"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="503"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="538"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="573"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="679"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="715"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="880" mass="102149" checksum="7A3680D64175B673" modified="2024-05-29" version="1">MRKSHNRCQNKQHTYNQFDFTFKIFNHFRIANPKNYFTRIKWGKDRKYNISDDLNSLVHRYYDVVKKNQMDTPLKLTKQIWCKYSENNPFLLNEKTISSTNLFKLKYSTPFETKTTRFRISTIVLFKLLKVFSYGPHNEDSLSRTISVYNQIWQSTYLTKYPDQKSESFTSLLRNLKNVNDSGEIKYKLINDWMSEGNVINQGIFENLVRLESELFGPQSAENLMEKYLSDPALKSLNLVKSLPVMQSLITGCQSRKLFELSKKYFIEILNMNLKPANSVWQNFLKFFISNGKTLEVLEFYDALKKSNVTSKEYLQTHSLGILINALISSSLNPTNKKVDLKSGVESAARLFADMISNNVKPSIITINNLIAAYSKVENQNAVNYYYSLIAKYNLKPDLFIYTTMIYSMMKSSQVSAAEKLYQNVLDLRLKPDLVLYCSMIHGYTLNRQMNNALKLEAEMRNNVTNFTLVAFHVMIYLHCVNGDIKKGWERLEEMESCGFTRSEITYNMLIQGAGLLGDLSTAKSLYLNMQENDIKPTTTTYNNLIFSHSIHNDPVGALEWYSNMFNNGCEPDVYTFNILIRNNVKEGNFEGAMDSYKKLIDSGLDPSHKTFHPLLQYQVRRGNMKQVRVLQNQIKIAGLEPKIETHNVILQSQLLHKPNSSALLHEFKLMESEGLVPDIRTFDMIIRAYGSMGKTISARRWFNRALNTKGLIPDTQIFNSLIFGYAKHGRVEIIQEIIKEMEHYGLKPDRFTYKILLEMASVLKKRKDANELNRSNQLKLINMMRQEESDLKLKNMNKYIPPPSSNELETDDDNIAATFNEYTIRKAQTLVKNIKINKTGGNIEKKKIFRNYKTEVDKVEMEEEFLNLDEGFNTFKDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1C5</accession>
    <name>A0AAD5U1C5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA methyltransferase 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">TRM5</name>
        <name evidence="12" type="ORF">HK099_004813</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010000351">
        <property type="protein sequence ID" value="KAJ3219119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1C5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF43">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="11">
        <location>
            <begin position="94"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3219119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="390" mass="45091" checksum="A2B698322C163A87" modified="2024-05-29" version="1">MATIKSLILNIKRKSSIVNYTPEPSSRLVLINRIFDKLENFKNFSNEKITNFLKETEASVTNYDLNFDYDYFTVDQILKSILPDELSNEIPSSFETIGHIAHLNLRDQYKPFKFIIGQVILDKMKNIRTVVNKLDNIDHTFRFFKMELLAGDNIMNAEVKESGCTFKLDFSKVYWNSRLQMEHDRLILKNFKRNDVICDVMAGIGPFSIPSAKNVGALVFANDLNPNSFESLNENIKLNKVAHKVKCFNLDGRIFIKESILELNKEELIGELRENFVPTKTARVKDTDAFRGLLTPYKHRLPKKFKLPIIHCYCFSTEVDNLEADVIERCSKALGYKLTKADILNFHRVRDVAPRKEMVCISFTCPEPVLFLNNNEADNTFDHEAKKIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1V6</accession>
    <name>A0AAD5U1V6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dihydroorotase</fullName>
            <ecNumber evidence="3">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006956</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000637">
        <property type="protein sequence ID" value="KAJ3214248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1V6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="8">
        <location>
            <begin position="63"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3214248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="36998" checksum="752E0676FAC6691F" modified="2024-05-29" version="1">MKLVTPLLEKSGVRNALVMPNLKPPITTTSQALSYKKELQVLAPNVNFLMTLYLVPELTPKEIYLAKKSGVVGVKSYPRGVTTNSDSGIESYTAYYHIFKAMEEVGMILNLHGEIPSDADNGVCVLNAEEKFLTHLKQLNKDFPNLKIVLEHATTKAAVEMVKSLNDNVGCTITIHHLELTVDDWAGCCHCYCKPVAKFPYDRKALQDVVREGHKKFFLGTDSAPHARHLKEGPNSAAGVFTGPYVTEYLAHALDSFNAIDKLEGFACINGRNFYGLDVKKDLINGQNRGISRLENSNFKILDELPFKDDEGIERTVVPYKAGKILNWKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1V9</accession>
    <name>A0AAD5U1V9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PNS1_1</name>
        <name evidence="10" type="ORF">HK099_003593</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000236">
        <property type="protein sequence ID" value="KAJ3221333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1V9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF4">
        <property type="entry name" value="PROTEIN PNS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="549" mass="61482" checksum="22E82A2A68BC18E5" modified="2024-05-29" version="1">MSYYNSQQTQWSQSQQQPLYHPAPSTTYPNYNDKNYNNNQYNQQYHDPQQQYYQQNNQYYQQNNQYAPPPSNAPLTTASAEKFVKKPKYNDVWASILFFLVLAAFGVCAYFGVNTAKDVYLNIISKPKDASKPVDSPLTKISERDILYTVAIGVGGGFVFSLIYFFMMQLFAGSLIIIQSILLVASLLGVSAWYFYQAVYIPAVVFLVIGLLFAWFFFSWRSRIPFAKVMLKTVTKIISGYPATILTGIFGLILEMIFLTVFLVTVFGWIVKINGPETFGIDENNNSTLNTNSNSTNGGFNTRNTRRTVNSSYALYGIYLFLLFSYYWTTQVLKNIVHVTVSGVFATFYFLGVSNGNGKVVVNERNPTLKSAKRAVTTSFGTICFGSLIIALIQTVRAMLRTLANEAADDGNIALMFLACCAHCILSWIEGLVQYFNHYAFTQVAIYGKDYCSAAKATWALIQTRGVDAIVNDNLIGAVLTMGGLFIGLLCGGLSYVFYIFSEMPKDHFAYPLTMFLFCFIIAFTEFLILSEVINSGVSATFVCLSEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Y4</accession>
    <name>A0AAD5U1Y4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-rRNA-processing protein esf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ESF1</name>
        <name evidence="8" type="ORF">HK099_003550</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000232">
        <property type="protein sequence ID" value="KAJ3221403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Y4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039754">
        <property type="entry name" value="Esf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056750">
        <property type="entry name" value="RRM_ESF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202:SF0">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25121">
        <property type="entry name" value="RRM_ESF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ESF1 RRM" evidence="7">
        <location>
            <begin position="173"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="6">
        <location>
            <begin position="593"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="48"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="374"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="450"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="511"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="686" mass="79684" checksum="4EB5C33317213FD9" modified="2024-05-29" version="1">MSESSVISDERFKRIQSDPRFKRPKKDDSKIKIDKRFAGMLKSNFSKTKKPLVDKRGKTIKKNAPLEDMKRFYKQDDELEEDEKEKENNDSSDEKKIVENVESVELHSASSDSESEEALSDIQKSDKISGFDLARGHGQVESSEEESDEEETVVGQTSQNEEEEENIPLGDETNRIAAVNLDWDHIKAQDIFKLFHSFLQTKNSATGKIVSVKIYVSEFGKAKLKEEEMGPPKEIFEDTNKLLVDDDGADFDEAKLRKYQLDRLKYYYSVTEFDSVNTAKEIYNICDGTEFESSGNFLDLRFIPDGTEFLEADVIDSCYKEEKNYVQKDFQTKALQHTKVSLTWDQDDFDRVKVTKRKFTKEDLKDMDFKSYVASSESEEEDEEGLREKYRSLFMGDNAEEEESDKEKMEDMEITFTPGLSEKVGKAALLKKDKIFEDETVFQRNLRLQKEKKKARKNQRKLAEKEVDSDDALISNEDDPEGGFDDEFFANSSDDDLKQNSKSKKEKNKKTKESAAERIEKKKNLEKLNLLMSNENSENTNMNHYEMKDILKMEKLKNLSSKKKSIKKKVEKKINMIKQEENIQDDFKLNLKDERFKKLLEDSEFHIDPTNAKFKKTENMKLLRNEIQKNKLKNMEHDTNFSTVEKIENEVSPSVGSNLKSLVDSVKRKSEAAFSNEKSGKRFKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U205</accession>
    <name>A0AAD5U205_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Homocysteine S-methyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HMT-1_1</name>
        <name evidence="7" type="ORF">HK099_003009</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000204">
        <property type="protein sequence ID" value="KAJ3221863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U205"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18581">
        <property type="entry name" value="ABC_6TM_ABCB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="222"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="529" mass="61930" checksum="085E340B903CC14B" modified="2024-05-29" version="1" fragment="single">MLWISIFYFVIALITAANFFLRWPRIQQASNLNEETPLLVSNRQYAIQPVSKLLLLFSLANLFSTYIDIVLTFLSLFLLKDSNLQQILSSLLIFFSWVLISTVIAFVRSAIRNGTISHYTIYIPVFFFCSTFFDTFSFFSQYWDGAANFNVLRTVALINLFVRMLFLWFVVVYILHNRGLLKVADTSENSRNISTWNNSREKILKLAPFLWPKKNSLKLVVLLCFMLLLGERIVNIVVPLAYKYIVDQLAYDPKTFAWLPVLYYVSFRFFQGSNGLLGALRSWFWIPVSQYTSRKISVKMLAHLHDLGLEFHLRRKTGEVLRVMDRGTSSVGSLLSYILFNILPIFFDIFAAIVVFVVMFDWIFGIIIFMSIFTYIFLTVWITEWRTKFRREMVELDNAYNARYLNLLNFSIYYFRAVDSLLNFETVKYFNNAEFEVQEYENAIVKYQAADFKSLASLNVLNLSQNLVITVGLLCGSLLCVFRISNGQSTLSDFILFMTYSAQLYQPLNWFGTFYRMIQQNFIDMEKMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2A6</accession>
    <name>A0AAD5U2A6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="12">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ACA10_3</name>
        <name evidence="15" type="ORF">HK099_004482</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000318">
        <property type="protein sequence ID" value="KAJ3220038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2A6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000193">
        <property type="entry name" value="Plasma membrane calcium-transporting ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0106">Calcium</keyword>
    <keyword evidence="12" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="10 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="13">
        <location>
            <begin position="273"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="14">
        <location>
            <begin position="915"/>
            <end position="1020"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3220038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1024" mass="114187" checksum="852FA9D77C7F76BE" modified="2024-05-29" version="1">MTFMNKEKTISLDINEEKYISIDSASNNEGDENSKFFIQSLTEQLETFVEQPKYLEEKLKFKAPFLLNDEFGITLAELIGLISFENRFEKNQLSNLNSERFGGVEGIAYLLRSNLKAGLALNQSKNKWNSEISLQKLKQSRKCKNVSIFKKAYRRLLSKKETESNDELNALKGDVSDGFIRSETFGRNLIKIQKSKSLFRLLIESIRDDAILKVLIIGSVIALIVGEIEDPVNGWWDSFAILIAVFIVSSVNAVNNYTTDKKFKSLLMLQSAIKTKVIRDGRMDEISSWDLLVGDVVTLSLGDEIPGDGLYIRGENLMIDESPLTGENQAVRKSAEQVFLFSGCHVSEGSGFMLITSMNYFLYYLYLPNLGVGVNSTSGRIQQLLSERQKQLTPLQIRLEFLAKQIGIIGFVSAILTFVALIINWGVKFHYRSTMENAVIVVGEEISTILHFLIASVTILVVAIPEGLPISVTISLGFSMFEMMKDNCFVRQLHSSETMGAATCICLDKTGTLTENRMTVVKAVFGDRIYNGERSETGKNNEKEFHSKTVSDELNDLITENISSNSSCFLKREEGKKHATFVGSATEGSLLVFIEKLGNSYQDVRNNITRAENGVWQFDSNRKMMSTLIFPCIKPPTIDPGCEYKYTLHVKGASEIVLSLSTHFVDRSGTRVCEMSESDRARFLDIIKSWAAGGWRTLALAYRATNVHPNDELERHIRPEHDLILIGLIGIKDPVRKDVAKAVSECNRAGLSIRMVTGDNLLTASKIAQECGILKPGGIAIEGKRFRNLSREDKIKLLPHLQVIARSTPMDKFDLVTLLKECGEVVAVTGDGTNDAPALKAADVGFSMGLSGTQVAINASDIVLMDDNFISLVAAIKWGRNVLNSVRKFLQFQLSINLIVIVTTLFSSAVVGEPIINSASLLWVNLIMDSLGALALASEKPDDRILKQRPHKRFSKMLTENMKFYISIQTFFQASIIISAKFNLSSYVPILNKQVIDNGDSELYELELKKHVSTILVTTFTTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2W0</accession>
    <name>A0AAD5U2W0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000273">
        <property type="protein sequence ID" value="KAJ3220790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2W0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF34">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="36"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="513" mass="56729" checksum="FCEAE24D63653A61" modified="2024-05-29" version="1">MEEVKLLSTNQEGEIQYTNITKRLDNLNWSKWHTKTTIVLGVGWALDAFETSILSSVLNLIKEDFNVTSVTEASLMTSVWLIGGMVGAIFFGWVGDRAYSLFTLLTSLSPNFYMFLIFRCLTSVGVAGEYSAVTSSIAEFVPSKHRGKLSVLIQGIQIRFVCSELKNVLGTWGVGALAANAINIPLVDNLPPHVAWRVACSLGAFASIFTLFARRFLPESPRWLLSKGRIDEAENVVKNIEVLCFQPNNGDNIEKSLFSVGENASFLTQIYTLWKTFPLQILFACTLDLSQAFGGYGMSNFMSLIILPNIVKESDIPRFYTIASLATFPGIGLAALLIDYIGRKKLLPLSYTLAAISCLMIYPSYTKKSSSSLTLSFFVFSLFYSSSWGTGYSMYSEIFPTFIRSTGIGMAVCVGRLGGFFAPLLTSYIFEKGDENGTKNVFGGFILISSFFLITVIAAIPFAYYGTEAKGLSLESACEEVRCSFDEQERNDIELLDRREVIPLENLTSLNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2X0</accession>
    <name>A0AAD5U2X0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000270">
        <property type="protein sequence ID" value="KAJ3220834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2X0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="273"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="436" mass="49525" checksum="F6A87FD6C8628F3A" modified="2024-05-29" version="1">MEETINLNAITVKLIIVVFLALATSYLLTQKKFYNGRNKEKEFEKKSTVSKKHSNKKDIKSILLKTQFEIPETVESSLNSPLSKSKLKKLKKSKIPAESNEQDLLVLGKLANETSTKLKKLVLNLHKPVAATTTSFNKDTQEAPITVTTTNDSLNDIESKTPFKEFTPIKMIEKRYGVSDKKNFFNLDHTPNNSIFTIKSEQAKAMPDAKINVGKCKNEDQSTSASATEKLVVNRPSKNYQIDENRAMRSYKNKMNIEKKSLNDSILLLMESLKAETQKFENCKRENLKLKAEVEELSTELKCLKKELGTEKKKSSNIIKSEIDYYKQLSEKLALQQRKLDKIAAHKNADNASVSAIQKSNDHAAPLKIVEKYFHENIQPDEAYENGLKAGSSFTPPNREENLELKIKNIIKYNDVNYEIDTPNERAVYLPNAAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2X3</accession>
    <name>A0AAD5U2X3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002189</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Cd(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48775"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000170">
        <property type="protein sequence ID" value="KAJ3222557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2X3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337:SF0">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0104">Cadmium</keyword>
    <keyword evidence="5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="473" mass="53645" checksum="3A9355DF4E442DC8" modified="2024-05-29" version="1">MTQTTNTSEWNPTSWKSKSITQDVEYSDNDALNKNLTKLSSLPPLVHHLEIDKLKNQLAEVAENKRFLLQGGDCAELFEYCSQTPLENKIKVLLQMSLILVWGGRTSVVRIARMAGQYAKPRSKPTEVINGVEYNAFRGDNVNGLPLSERKPDPHKLVEAYFHSAATVNYVRSILANGFADLHHPDNWTLDSFSLQHVKSPQIRSEYQSIVDRLLDSMDFMRTIGADSPEDTTSNNPLNTVDMFMSHEGLLLDYETSLTKKVSVKVNGQTEERFYNLGAHFIWIGDRTRQLDGAHIEYFRGVQNPIGVKVGPSMEPEELIRLLDILDPNFETGKVTLITRYGATKISNYLPSHIKAVQQTRHKVVWCSDPMHGNTELAQGGYKTRRFENIAAELGKAFRIHKDCNSQLGGVHFELTGEKVTECTGGSMEMTEAELPENYQTYCDPRLNYEQSLDIAFLIAKYYETERKPVFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U317</accession>
    <name>A0AAD5U317_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000485">
        <property type="protein sequence ID" value="KAJ3216303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U317"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="267" mass="30978" checksum="12A386196981E41D" modified="2024-05-29" version="1" fragment="single">ELTNVSKLHWSLSYLFDSSRVSVDTDFLQTMEILKKAVYFQLCFGFPYVVNVDSDARLFEYAFGILLEQRLKNSVERNVVVNESFILQTAYNILSKENDFLRITAETRIGESLIAQSRGYLWENPQKFSPFFIPSFNAGPDLCFFIERCDGGGLIPVFIQLKLSHHVSRVAALSTTDPLKFYRDKNNKKIENYMEERKKCIDIINNQYNKTHIGILIAYPKSWLSSTYEKKDNDGWVRYEKVFDGTLENRIFDETHLIYLAGIGITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U385</accession>
    <name>A0AAD5U385_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003565</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000234">
        <property type="protein sequence ID" value="KAJ3221364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U385"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051242">
        <property type="entry name" value="WD-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324:SF4">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="70"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="407"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="541"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="906"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1063" mass="121089" checksum="F9B073A40EDEF25A" modified="2024-05-29" version="1">MGFSLPPINQQQQVKMYDKSDKQIKARLNDHMQNISDAKNEEVKLATKLNQVNILKDSANYRTEREINLQNFRELLLIFQTAAKNGNGSITREQFKFHFTSLLGRDLNEEQMNHLFMNIAINSNDTIDWNDFSTFMLLRAEGQKRMREAAENQLFEIDPAILHRLPIQTPHKDQIGIILYLNKVKKVKNNQMDPDEAKTKSKKVNTWIHDCKYMENTSQLVIASDDHCISFCDFSTLLCNVRLNIGEIIPLTIDIWYDVENPDTNESMLIFGTDSGMIMIFYFQNDILFKNEATQKKGSTIFLDSFVKQNKNTCQLIKRKAHSDWVLKIRYYSTLRSIISCSPDPKESLVFATHNNKKKWTFISLPVHKGVNCFEYCKFPAVLVTGGTDRQLRIWNCHRLKNPMAALRGHSSPIIDIAINESSGQIISLSTDKVVKVWDIRKQNCVQTLMDPFTHRPEDSLSSINFSNVNGGSLVCASYTLTPYQLQQKQVSVKVPKSHEFPLRAAIYNKEFKQIVSGDDGGVVNVWNPLSGQKTFRLVEVHDKLEEITAMAFDNNNRRLITGGRAGTIRMWNFNNGAPLHVFKGDSSEVTGIVYFEMKETDWIVTTGWNRRITMYTYKESCFEIYPSKIWPEMNQSPWHSGDILSLSFCPPNLLATSSVDGEIIIVNLITGQIQFRLTAFDYDLNSNIKFTFSVDKVMYLYSRNNIIDASNLVSIGSDGKIRFWNTYKGILMGEFDGGHDNEGICSMVDLLLTSYISVWDISETCWEDTEVFTMPLISSFRGHVKSVLSVDLIESVDIIVTASADCTARIFTYKGEYVGTLGQSDLWDLTNPTTFQHPLKPLEVIMSELEACSDDQTFQKLKEMSTKTNQSKKKTKKIFKENIYEEVPDRNRILSRAATSKSLSSSKLLSRSEDNSSEEESDCEAANGKQVDNHCDWDLSRTSSNSISSSVEKLIEGSNAKKVTMKGEQIYFDESVVDHAVDGGIKADKYAKLKKPPKTAELMRKEYGTWYASSIYSKSGKYRPAYVGKPFTKKKINILSKSIGIYNSLKPVELSEILDIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3T5</accession>
    <name>A0AAD5U3T5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA-specific adenosine deaminase 1</fullName>
            <ecNumber evidence="8">3.5.4.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">tRNA-specific adenosine-37 deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_004340</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically deaminates adenosine-37 to inosine in tRNA-Ala.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA(Ala) + H2O + H(+) = inosine(37) in tRNA(Ala) + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:50968"/>
            <dbReference type="Rhea" id="RHEA-COMP:12855"/>
            <dbReference type="Rhea" id="RHEA-COMP:12856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.34"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>1D-myo-inositol hexakisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ADAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.34" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000300">
        <property type="protein sequence ID" value="KAJ3220463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3T5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043829">
        <property type="term" value="F:tRNA-specific adenosine-37 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46516">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46516:SF1">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00552">
        <property type="entry name" value="ADEAMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="A to I editase" evidence="12">
        <location>
            <begin position="63"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3220463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="244" mass="28061" checksum="EF9420F7D62962FA" modified="2024-05-29" version="1">MKTACRSKIDGDEIQKISIKFFEQLPKKGKPVKKNERQQEYTVLATILMEDKSFADCELKVIALGTGTRCLGSKQLSDSGTIINDSHAEIICKRAFQKYLYAELKKYFFKKESSILNFNVEKGIWCLKDEIKFHFFVSQAFCGDASMSFLKEKKVLLNENVEEKESFNFFDEKEMENPFKRQKLLLNFSENLIRGRNDIEKLGFCRTKPGRIDSDPTNSMSCTDKVLKWSTLGLNGSMLSNVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5U9</accession>
    <name>A0AAD5U5U9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein S-acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006805</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000061">
        <property type="protein sequence ID" value="KAJ3225434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5U9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="130" mass="14201" checksum="CEDCBC61BC5112C0" modified="2024-05-29" version="1">MDAIFSAIKEGNTDKVRELLLKDKSLTSQKYRDPTVKFESDVELDAYKFLGAYIGAISVLQMAILAGQDAIAKDVLERTLKDDLDQTFGGGNTALHLATFLGAREVVKLLLERGANRNIVNGKGFSPLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Y7</accession>
    <name>A0AAD5U5Y7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transposase putative helix-turn-helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000056">
        <property type="protein sequence ID" value="KAJ3225636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Y7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021027">
        <property type="entry name" value="Transposase_put_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12323">
        <property type="entry name" value="HTH_OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase putative helix-turn-helix" evidence="1">
        <location>
            <begin position="145"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="23040" checksum="7DD7EF024847DB50" modified="2024-05-29" version="1">MFKKAGYQLYLMLLQPKTPKTLISVKKDFIRNVDDLPQTNLLKLKDPLLLFTNKNSLIFMLLKIYVLETMSKESTRQPFWNPIYKTLSTNLLIPLENSESPLIQNQIEDSNMLSIKELTLPEKNQPVDPFTFVDFPEPETEKVIKCVKIELYPAHYQKKIFKKWLNTARYVYNKVVNETEKKKSTMNFKIFEINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U608</accession>
    <name>A0AAD5U608_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Subunit of the glycosylphosphatidylinositol transamidase complex-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GPI16</name>
        <name evidence="2" type="ORF">HK099_006331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U608"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007245">
        <property type="entry name" value="PIG-T"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959:SF11">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04113">
        <property type="entry name" value="Gpi16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="294" mass="33982" checksum="07C453A945D5E9EF" modified="2024-05-29" version="1">MAGISTLFNAYKLFDANFHSAGVHLKPVCNRNDDFNSDLTKNYWSLNKIFERKIPKACAVSSKSLVELSLPNKTGFKLNNSPDKILDNGNFIFDLQNKIDFDIGVEWESNQELNFGFGQEKGGINIDLYNYRDQPLTVAVFQMIPWYLKFYLHTLQFQSMPLNHDFNAESLILRNRDILNETYYQPAVERMRPTILEYKLSLPAKSKIVMKMDFDKSFIRYTEHPPDANRGFDIGPAIITFGKKEEKFYTNNLLINLPTPDFSMPYNVITLTCTVLAFLFAGIFNLMIKNYKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U641</accession>
    <name>A0AAD5U641_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Ca(2+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_001945</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000160">
        <property type="protein sequence ID" value="KAJ3222777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U641"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000039">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="17">
        <location>
            <begin position="107"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3222777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="447" mass="49314" checksum="1CBF436B0FD174BC" modified="2024-05-29" version="1">MNFSAGNGETVAVTGDGTNDAPALKSADVGFAMGIAGTEVAKEACDIVLMDDNFASLVKAVIWGRSVYDSVRKFLQFQLTVNVTAVVITVFSSLISTVESVNHEPNSVLSAIQLLWVNLIMDTFAALALATDLPTDELLNRNPAKKSDSLISKEMWKQIVGQAIYQIVICFVVYLKPYSIFPFAKPAVAMSVSEDPFVNTVVFNTFVLCQLFNELNSRSISRDLNIFRGVLRNYTFIVIIFFSLAMQIIIVQVGGKIFHLREGGLDIISWLICLALGFGSIPVGFLIRLIPTRDPSPEEENLKLESEIVNEVEELQRVVIKKIEIQHGKELTSKEIELWRSAINRIAIQLKVVGTFKSDVERESFTEGVYIGAQVAMLVNETEKEEKAGTRKSSVSSMPLGIPSTSHIGINIGDSRGLSSSRDLWKNAGTRVRRETGVIEAFRRARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U683</accession>
    <name>A0AAD5U683_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001778</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000154">
        <property type="protein sequence ID" value="KAJ3222893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033228">
        <property type="entry name" value="SZT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14918">
        <property type="entry name" value="KICSTOR COMPLEX PROTEIN SZT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14918:SF3">
        <property type="entry name" value="KICSTOR COMPLEX PROTEIN SZT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2223"/>
            <end position="2247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2416"/>
            <end position="2437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1441"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2425"/>
            <end position="2437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="3011" mass="344378" checksum="A5BD1C109333CD33" modified="2024-05-29" version="1">MDAKSCVLLIKEPFLFTKREHDLWVVDKLYKNFSRSSINSTSENFNESIQILELSLENNPFQKNLQKNGIDANAVIRITPQTKIISFAKKYRLVFLIDISASMSIVGGTGKPKVHLTVAFETYIYSLSDRFIIYFDYTFSVCKCIDALTRSFSINSSLHNKTFDIEPELNVTVLADCGNSIFRKYQKSSTSEFCRSFPIKVLIHDLKVSPSLVESFAETLYDTLNAFEVELVKCRQKDFEENDNALVQVNNSSVISNENSPIKSNIQDSIPIKTRGGCIYDSLENAMFALGLFSNHSLPAVVLITDGVSYYPGVNYGHVSDNEFVRFLAMATFGKFLYATDCRYMEPLNHCMIDSPNFFHQQLLFRELNLSKLVADNVWRTVHAGSVERPVDLVRVECLSTIELDDSPEISNEEIYFPWFTTSQPPVVYQVLCGYRDYSMNLNLTHILSARLLEGYSIRSVQISQKLNRPTKVEILLALPWIPNVTVFYTIRTSWINQEKPLLEGLNPKHRIELNILAHRPFVLLFVNQQIETDVFNTALHEKVFGIAESDERLKLVGAFNSRYCLSFFSTDMQISPPYQEQPKSFENTRRSRTPSTSPRQYWTSLGDFVMNKGLSVEDYGFDIILRTYDSLISTTRKEIENQRLTAYKALSKFLGNWSSYNFGKGVYLKLIFTASDDEIPIGFCYLRISSETELAFQIRIFFSNLSSKVREGIVKNLKDNISNLTDAGFHLVAVCEKPLRQLLLRYGVEGKKPKKNSKLRSSSLNIEGGHNYQIPEKYSFFAVLRAYLRNKSWVWFSGVNKLIGNFFRGFENENGINDLAFDLIYNRRLQEGFLPVHESNYSTTLYLEKKFTNATSSVQFVLKKDFVNGDLITELWLEPACSSMKNNYKFQSTLDYEIIEEFEAYSNFMEITDKSITNTLYSFLALNLLAKKSDQDLMTFEKIVKNYENINSNFDMRLILNQCSYYSLFSFQIPFMNNIGLFQSGVEKSDEIFQTPCNSSSLVSSQLNLESESSAAKGEQGENLNFKFEQDFVAESKKEIDFIFETVQRYLKSQNPNEKKLILITRFLQSSLAATCDGFFDCALLQKDKDFENDFLESVKSFLSTKFTSEKVFLESLKCSNCFIKFYNSEAFLLIIAPRFCGFDIPTTPNYLGISFFECILPSIPSVNKPSPLPFCNSINETSESRNFIFYLPNVDLKENDENTVPNCHRLITFTGNITPDSTSDKSLNASLHQFAESFLNDLKIKYTKVKGSIIYFGFLQHEKFTATDFDSIINVAMEEVVEVDFTNYLNAASLVSKVDAGFYGCLNSSKSNSSFNIDSGIMEILQESFENVSNFLSDIREYYLFKPKNLKSNGLGKELEDLLKYSLNPMFIELMYLIDRPNSETIIFGSKKFPISYPKEMSDTFLNVGTESNFLGSKDGTRAICRINIYSFGDKIVGNQNFNSVLEEQQAAIQKVKNEINYFLDKIVLEQLLNLNVTESSLALVSFLITRRATYYYQVFNLDSFMDATFNTSKDLSSTNKPGDSDLDISKILKETPDAILEFTLHFIGGKELNLIKNLSLKKNSIHGFDIEKYGKNYLVTKNEFSTGSIDISDSLETVSGLGISTERSSSSENIDMVVNSTSYFSYWFLINIDSEKSVAKFLLFSKSLDVRDQVDMIKDVAKGVRSCCEKLNALFLLQKLNEKKVASKYLIIPGYESLEENGVADDSFTDEGKRDWKPNDGSEVKLTSYLKHLFPLHWRLKPQVALTEILSYLHPFAIMNRKNSIVYVKSTNTIFYIVFSIYGDIQQETGLEDSTNKSSPIMKLSPAINEELFSDSPTIKKTSFPGISNFKTDSSMLMLEVFGLEDPGNEISVEFVSRIEIKLNSLLLQKLGNFFIRGFSSTVKLTKADVDFIISQHGSPHSKYLPLPKSVYKVYLFQLLLRQKLLDHFSIFTSVDISNALERYYESRNVGEPSNSSSDIVSFGDFSFLYNCVPSPNPSPQEILLGQGISCINIVVLDRAGHVILPKDEDFVDWNEELNTIVTDTQSKLWSSLPDANYSIGIECWIHGNINVDALFFKLEAICQSTLSEYFVEMLADTLIAELPTIREDENVILSKDFAVISEKLVELMRIASAKTLMHNNSFSSTITLPSWVFNEFLNDVIILLNESHSFLHPVAIKKITENEKLTFTIQNKNGRQKLSSLMDSSASYKNQSDCCIILAGLCDENSTCLNVRPKNLLERKGSMGSDSSSSAEKHGRRLSSAEELDNNNSNALSMLTHIGKNSRIFGNVNLKMPLDNISHYPGFYHCGNYNKCFLVLVVTNETFELLSHNCNKSYIDQVNKKLLKILSWNNIRIQYLNAAFPLTSPVPPWFSTSLSSNNFFEKNLEFCWSKQNLLYSTQNDVLQARSIDFLEHFIRQNLYYQKKDLSKSHATQNRKVRGIHHSNSSSSDVGSGNRSHEILDIPFNTLLNAVRRVKLYYFAKYPIFFSESREKIIEKPFFFPPPFEADFSKKEILFKKWFKKIISGYQTEYTTYLAQLGLEVALLEKEWEKSMDLAPIPRFEITDGLFLDTEIIYLKKNFGNHAVLIQFGIDGLHSFINMFSLTDIDISSSKKEKISEEYSLDDFNSECEKISISLQLHSFSYDFHIKKFKEMLEDKEIDSCPIDLINTIILFHEWAMPKLYFSHNRIFNQPFVSETARNLSPSLLVYILKNPSRYGFNSLFQNNKKRAFFLVSKTPDFNFKPKFEAIDILPETRNSFVLIVYPNSGVLSPPTENLLSFFVLLIKPESYHNTQSVHNNLKFSVNSDPLLEYLDNGFYLGDIVKCASKKLELLLEQAVIFHGRDSLWKQLINEKTHKVNATLPESVSFDNTEYNTTEWTKLFLEKIAPNSRPLTDIDDQLGKFFRNINIPWNEVLDFLIQKFRETSRELTENLKSKERRIVLFNSKNNDYLIHFVLTTSENTGIGTVHSGKKDTLNQKLMSHPNLVPSASNLILHGFAVSREGMISEVEYEHLDCIVQAISVWLYCRLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6K3</accession>
    <name>A0AAD5U6K3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Imidazoleglycerol-phosphate dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HIS3</name>
        <name evidence="9" type="ORF">HK099_005062</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000038">
        <property type="protein sequence ID" value="KAJ3226354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6K3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000003">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="entry name" value="Imidazole glycerol phosphate dehydratase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133:SF2">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE HIS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="172" mass="19295" checksum="6DF0F7D2353DFFDE" modified="2024-05-29" version="1">MSKLRRSEVKRKTNETDIYISLTFDSFVDQKIEINSGIGFLDHMLHALAKHSRWSLILSCSGDLHIDDHHSVEDIGITLGLAWKNALGEPKGIKRYGYAYAPLDEALSRAVVDISGRPFACIDLGLKREFLGKLSCEMIPHFFESFATSAGITLHVDVLKGVNDHHRLHLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6N9</accession>
    <name>A0AAD5U6N9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005415</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6N9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031647">
        <property type="term" value="P:regulation of protein stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000044">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024729">
        <property type="entry name" value="USP7_ICP0-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029346">
        <property type="entry name" value="USP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF644">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14533">
        <property type="entry name" value="USP7_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12436">
        <property type="entry name" value="USP7_ICP0_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="159"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1053" mass="122731" checksum="CC774182FCFA2076" modified="2024-05-29" version="1">MSVPNFDKNSPTPDIINIKNPLNNPVPANEIEKILDDLDYPVVDQLVYKWEIKKWDEFIKQERVYICVQFAIALQNVEDETVSKCMTARHRFAPNQVDWGFNHLVSSTVLNQGVPDFSRPIMEKNSLNVIVYLKIVKDETGVLWHNLLDYDSKKETGFVGLKNQGATCYMNSLLQSLYFTSYFRKATFQIPTVNDDPTKSVPLALQRIFYNLQYSDDPIGTIELTKSFGWDTLDSFMQHDVQEFNRGSAAEGAISNLFVGKMKSYIKCIDVDFESSRIEDFYDIQLNVKGCKDLTESFIDYCAVETLEGENRYQAEGYGLQDAKKGVIFKKFPPVLHLQLKRFEYDMERDDMVKINDRHEFPLEIDLDQFLESDEDRVGEYRYSLHGVLVHSGDLSAGHYMAFIRPEKNGKWFKFDDDKVLPVTQKEALNDNYGEISKPGQQFRQSRKLTNAYMLVYVRNSQLDTILSPVTEADIPAHLRKIYNFVIFIPLLVERLSKEREETEAKRKEHEDLHLYIFCKVITDEDIQNHEGFDLFDFDQLNKIKTNAFYRQQQEKNLLMEKQIQKNIFKVKKTDTFKKFKEIVGDRFQTEMSFRLWNMVTRKNKTIRTEQPISDFDNENKTMEELQLLISRNSEMKLYLELPDIEKINNKSNLNAIKQFTDKDVPIMLFLKYFDPFSQTLEYVGKVTVPSRSMKVMELMPLLLNRKKLPSDTNLILYEEVKQGMIDLIKPNKSFINLELLDGDILCYQKELTAKELERLQLEQPNQHLTIPDYFDFISNRVVVLFKEFPAMDHGLQLGMKENLKNNVEVVLSIKMSYDQVAKKFSEALGKDIDPMKLRFTSCSNSGLPKLPIKRVEKLMLSDMLSAGGHYRQQVNVLFYEKLDCSIIEFDSKRNLKVLYVDENLREFGPLEFLVLKAATFSEIEKMLSEKLKLNENAKIKFFDIQYGKAYQYFETEDSISKLGENSTLTAQGEVFSETRIRLQKRIDYNDKDFSKVKICFCSGDASTLRLFSNDEVLYNILNPKTEYIGLDHIDKNLANKKPVEKGIILKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6U4</accession>
    <name>A0AAD5U6U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_004522</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6U4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="20"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="97"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="478" mass="54746" checksum="58165EE8F4753AC7" modified="2024-05-29" version="1">MLRAKTISRQRVKSSTSYLKNQVLVTIRIKNEVDSENLIWNVSEQNTIYLNNHSTNIFKFDNIVTSSANYLVYTRNFQKIIASSIIDGLNGIIMAYGQTNSGKTYTMSGKESKVKSEKGLIQYSIEDIFSIIEEQKQKEYRLKISYVEIYNETIKDLLNPLNPVEIKILIDKETNGTYMAPIKHEFCLTQYQVLDLIKKGEANRQLKQTDGNFRSSRSHTILQITVDAKDLRNSFVTHSRIVFCDLAGSEKLDSNIFRRKEGSFINKSLLALGNCISKLSDPKEKDNHIPYRDSKLTRILQNSLSGNSLVGVICTISARERNKEESLSTLKFAQRIKNIPINATKGRERNVDQKELIKIYKDEIKELKEKLVETDLKLAEEKSKTESLKKQKALINDGTKDVQDTQIFDNNLFKLELIKCRLSLVKNIKNLENLYLSARDNEVVGSIITDHTGSLDSVPSIISKITVFSFNWYHIFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U791</accession>
    <name>A0AAD5U791_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radial spoke head protein 4 A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RSPH4A</name>
        <name evidence="7" type="ORF">HK099_002129</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000169">
        <property type="protein sequence ID" value="KAJ3222575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U791"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001534">
        <property type="term" value="C:radial spoke"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22963">
        <property type="entry name" value="DD_CrRSP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006802">
        <property type="entry name" value="Radial_spoke"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13159:SF0">
        <property type="entry name" value="RADIAL SPOKE HEAD 6 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13159">
        <property type="entry name" value="RADIAL SPOKEHEAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04712">
        <property type="entry name" value="Radial_spoke"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="582"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="702"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="724"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="738"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="768" mass="83924" checksum="9CB424483F35489C" modified="2024-05-29" version="1">MSSEEESSRPQTSEGEESRPLSNEGVGTEIMSDAEKPLSAQENASADEVQPSSQRQSVSQLIKSQSSSKQNIAAPEKVPSVPNVFSGSTKTSKEDLFQNNVSESKANLESASKSGSKENLLAKASSKVGSKVSSRVSLTETPPTDATPVSQRASISEKVLSKKNSVAEDITAPNQPVEVVAAPAAGPGFEIPLQQNYAFLNQFSSYTKPEAWLPEEADLALATSFLKANQSSKPGAGNLYNHLTSVVMRVLEARPPNSVDLLEMLSADVKRSKFEVEQKNSPSSFNRVKPTPKELSLAVSKMKLMQKPEVEDPEQEAEIPDIMELSKLWEWGGVSFGQDETFVLSLSIKKLALEKNLKSVRLWGKIFGLQSNYIIVEGELKEGVTDDDDVIANGEPPAEEEVVAEESKPEEHFDADNNPIVEIPLPKPKTKVVPALPKENRSGNNKYVYYTASHAGGEFTRLPDVIPEKLQISRKIRKFFSGNLNKFVNSYPAFNSNEAQLLRCQIARISAATVVSPTGYYTFDPDEEGDDSDHVATILINNEYEGATNENLLNTSNWVHHVPYILPQGRITWEDPFASLKNNEEGEEEDEEDNDNNDNNSNDGNGGSENTGPETGPTILSPINADEDHGDIPSWVSRFCSVFSQTKFSPVLLRNNRWPGASVISYNDKFASIYMGDGQKNLGNPQQNFIVPKLPEIQKEFGSGVEGGFGSQTDITEQVDPTLEEEKAFEDSQKVKEDDPDEEEAGEDDGEGENDGGDEGGDDGSDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7A1</accession>
    <name>A0AAD5U7A1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000168">
        <property type="protein sequence ID" value="KAJ3222597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7A1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042091796" evidence="1">
        <location>
            <begin position="20"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="228" mass="24477" checksum="2CF2612699ADA6AD" modified="2024-05-29" version="1">MLKFPTLLTITILLKLISSQIGGTTQNVSIEGRYIGGEACSPIKQDSRDPSRVYRKHANSVVYMNFRYYNGTAPGTLSTLTASFYPTVDSYSLLNIPNSARTLIGGLGDVSFKSNSIYIDFLTNSGVMRSSIATFAEKSGRIYYVPARTVVITLDNGSPVSIEWAPSNCIADTCKCMDPGTKYAICGELGVGEEGTLCDGTNCNIQVYLAWAGTDANGRVLASASKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7E3</accession>
    <name>A0AAD5U7E3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="5 16">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">DGAT2</name>
        <name evidence="19" type="ORF">HK099_000566</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Endoplasmic reticulum membrane</location>
            <topology evidence="1 16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="5 16"/>
    <dbReference type="EMBL" id="JADGJW010000113">
        <property type="protein sequence ID" value="KAJ3223905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7E3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10 16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="284"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="400"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3223905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="441" mass="50835" checksum="2B616B7852248195" modified="2024-05-29" version="1">MHVGTLNVNLIAPFIRETLLTRGFISVNKNSINHTLQDSKSNAVGIVIGGAKESLFAVPGRNTVVLKNRKGFVKLAIQNGASLVPVYSFGENYLYKQVQNQTLKKIQDFLTRYLSFAPVIFYGRNVVTCVGNPIMVKKNENPTDEEIEFYHQEYMKGLTELFNKYKDEYDPDRIEDLMLSASFNQEELSNLTEVHNENETVDKVKKNKEQEFEFVKPQQVIKPSLKVFTPIKTRLNKKPQRVQLSDEIQQHQQHQKALEVKSVLTTPIKDREDWDCRFTISEKKPKNSGMDDYTPVKKLNTSKKSSPVTPRYLSYSNEPVNQLRGRKSSSDLLYSNKQQSNVTRAKENSGKTLQAKKNDKIYDTDEELSKLTKHFLKLSETEKAEDVLADGNLGEFESKLIEKTKKIKKLDKLLEIIEKEKEKEMQMKAQLLEKIKLFRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7H2</accession>
    <name>A0AAD5U7H2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase epsilon subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA polymerase II subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">POLE2</name>
        <name evidence="9" type="ORF">HK099_006193</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase epsilon subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000052">
        <property type="protein sequence ID" value="KAJ3225795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7H2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016266">
        <property type="entry name" value="POLE2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000799">
        <property type="entry name" value="DNA_pol_eps_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="8">
        <location>
            <begin position="229"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="473" mass="54498" checksum="6577B79AFF7860D2" modified="2024-05-29" version="1">MNSATLNRVIYQCFSPYGISLQKEAFNFLKESISDLNLNSVKDVQSWLTSVASEVLSREFSLNLKKKDLELIFTELINKSASKDLVVDNNKTTADLKDINPYFQVIDLFNITPIKNLIGCQGNEFLIFGMLTEMVEGKIHLEDPDAYVELSFNEISEKGPGVYTLNCFVFCYGYYDDEKIFNVSKIFMPPIEDREQTIMSQDFFVGKKEETFQDIKDLKLLENSFDVSIVILSDVWLDKPIVFTKLRTMFEGYNDNPPLAFIFIGSFISTPYKMDGSDQDNYTESFNHLADLISEYPSIAKASIFVFVPGSNDPLNSQQEILPKKQISEIFYFKLKLKVENLIFTTNPCRIKYFTLELVIFKDYFKNRILRNCIFSPEEKNGELQTQFLKTVLSQAHLVPLPTKLRPTYWMYDHCLRLNSLPHLLCLADIGETFWDDTLAKGTIVCNPGVFSNDFKFLFYRPSENTIEAAQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7I8</accession>
    <name>A0AAD5U7I8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">H(+)-transporting V1 sector ATPase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VMA8</name>
        <name evidence="4" type="ORF">HK099_002638</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7I8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="295" mass="34043" checksum="6E9D871DD2B4E08E" modified="2024-05-29" version="1">MIIDLFDFDFDVTFERKGNKKERVKEEMSGVGARLNIFPTRMALTNMKLRLKGAQTGHSLLKRKAEALTRRFREIVKKIQDAKLKMGAVLQAASFSYSEVIYSAGDISYQVRESVKTPQIKVKAKQENVSGVMLPAFDFINDGQNSFELTGLGRGGQQIQRCKDTYSKAVEVLVELASLQWFNYQTAFVILDEVIKVTNRRVNAIEHVIIPKIENTIHYITSELDEMDREEFYRLGSSISNLFITFYRLKKVQGKKKEKKDREEAEKENYVEKYGDVVETVNILAEYEKDEDVMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7T3</accession>
    <name>A0AAD5U7T3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7T3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF1">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="388" mass="43519" checksum="135DF5404BCC0CF7" modified="2024-05-29" version="1">MNSPARTTLLGSSIPSPRTIRKKMYQSKLEKAKKLRLENSFQKVLFHQFIFLFTGLISTLGAQWLNYRKAADSRSLLTVLCTYLGMILIVFLPLESSENYKSTQISLKNLSSPEEKTKSLPLPRKSGINHTGVIAVALLDVFGQIILTVGLFYIGSGLYQVIYSSVIVFASVYNRIFLKRTMDFKQWMAVITITFGLSLNALITDNKNPTMNKLQESSDQIILGFIITLVGTSIYSGVYTLNDHLMTSKQSKASPRDQCLWPLSDPDVIFAYLVLTLSALGHNVTYFELVNCTGAVATGVLQALRAVLVFFLSHFFFCDQDAHQCFTFGKGLSTFFVILGVLGFAYAKSLKLKEYKQLFSKGSEEIFLKKNDDGLTEENFFDSDEDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U861</accession>
    <name>A0AAD5U861_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-regulated stress-responsive transcription factor skn7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SKN7_2</name>
        <name evidence="8" type="ORF">HK099_005241</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U861"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="7">
        <location>
            <begin position="638"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="827"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="912"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="827"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="913"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3228231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="944" mass="108954" checksum="D3B67EDD5B98F4FB" modified="2024-05-29" version="1">MIYEHPEYKEYKPMFATLCEPLYKAINENDIEKIETELVNYDYDYDYVNIHIKYDALKYAIKINIMTLSSEKSEKLFYNYLLKFLDEKKLNLVDSLLNIPEKKIEKLKYLYPIKMYKIGNLSLTGVNDPMNYLTLNHGNGSPLLVPDIGIAKNVGCVKRYKENAVDIFPSNSQNGIGMKKLFWQVVGRKILDKNINSSICQFLKYRHKYYKNSSILLKSEESRAVDSIKLFIKKHKELDNVPGVSPSDVDVDEYKLSKLLMKKLNLESKSVEIPQDILDYLDQLGDDEDNFKKNVLAFYKFRHEGKFLNFEQQYVLIEDEKIINFFDSKTAANSYASKNGLSEACLIQPIDDSKSWGGKKRLVNSVKTPSDCGYEYKVDHQLSLNICSRENKISVIGVLDSGCFTTTINHENYISMSQSLMVALKNSVKITGWDQAIQKIIIDANPPKEKEILIGFDVLKSYWMHNEVTNVTNVSSVLKYYSKNKKDYIYHLIYYLFDKENSLKNDHLSIVTNEELILKSRNNPDKYIFALVSLFYDTDETATPLTRCTGIILINLIYDLSHIERFWSILYLNGISQLGYIDKRNVNLIHYLVKVFFIRLPSQMQSQIQYFTEHCVSQQDVLLYYHTIIYGKAGSTHTLDSDYSKLMKDIILENEKYNNCISWTEKGDAFVVLNSHIFSSEVLPEVFKHSNFDSFVRQLNLYSFSKVNRTYHRHNSITFEERSLEPKEFFHEKFRRDRPDLITKILRKNFTLTKRRSLESSYSSSSSSSSLKINIPKKKLSSSSLRSSSEVKLSNSCNSNEPDIFSSVSDSPTKTDWFFDDIFTSTRSTSPSTYKGSSPSSSRKGSQVSFQDLSSSYQVQSELTYQGYQTRENFENLNVSGSTIQVEEKRYVSVFSETEFMDLLILNDDESSTENTASQKSSLDVSSLLAPTKPDGSPLNRYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8A9</accession>
    <name>A0AAD5U8A9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Major heat shock 70 kDa protein Bb</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HSP70BB</name>
        <name evidence="5" type="ORF">HK099_006729</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8A9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000010">
        <property type="entry name" value="heat shock 70 kDa protein 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3228104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="524" mass="58054" checksum="269DAD141FAC68BA" modified="2024-05-29" version="1">MSTPLFIGISFGTLNSSISVIGKDGEFETIANEDGMRNIPSCVAFTSHDELVGTQAKLQAIRNPRNTIVHFRNLLSRSFDSEDVKSHLKDHRLPIVSSPDDESAPVYEVDFWENPSDEPTKQYLSPKQITTKYLEKMKSTAEAYLGQKVDGCVLSTPTCFDDGQNLALEEAAKESGFDTVFLIKEPVAAAISFSNESPKIDKLNLVLDLGGHNFNVTVLSSNKGLYSIVDTRDDNKLGGVQLDEVLVNLVVDEFKRKTKMNLRENRRSLLKLRNACEQTKRALSHREVAPCSIESLHEGIDHHGSINRSRFELQAEPLFKRCTALVMETLAANDLTANDIDEVFLVGGCSKIPRYQAFIQSIFANSPDTRIRIESNPDEAISKGCIAQAAIIIESGLDHYTAAYNDISLTTNVPHTTKSIGIADHNGDMVVLIAKETPIPVRRIVEFSNSIKNQKELYLAVYEGENKVAAKNALLAEIVVSDLTENLEVGEAKLEVTFTIEKDKILHVVAKEKKMGKTLKVIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8M0</accession>
    <name>A0AAD5U8M0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000009</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8M0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042130589" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="18"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="52"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3228454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="437" mass="50818" checksum="717ED5028AF8091C" modified="2024-05-29" version="1">MRSLLLLLVFLTSFAFSQYQYLSNNEVKSNLKHSKNNLPAYGSTTKKKINLPAYGSTKKKNENHSPLEDENFDDDDDEDTPVDPKHEATGYHEKFRKYSDPPFTHNHCKETTIRREWRQLTEKERQRYLEANLCLLNSPSERKGGKGSLYDDFVWHHWDIATSIHFTPLFLPFHRAFIIAYENALRTCGDNNEFDDVRTYWDIALDSFAPSRAIVFQEKYFGGNGNKNDDYCLQSGTFGGRIAEHPKKHCLRRNFDLNQIYTKGNAEATIGAMFTDELLEMSKKNGEIRQFDYFRNLLESTIHEALHFGIGGNKGDMSKADTAPNDPIFWLHHGNIDRVWSEFQKAFPKLAHTYNGKNEDKKDVNENDEIDLGPLKKYLPYGWDKKILRVKDVFDIKEWCYDFSKSVRWGEDGEIKDNIGESRIYRGFLVASQGPFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U930</accession>
    <name>A0AAD5U930_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008449</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U930"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="3">
        <location>
            <begin position="64"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="27113" checksum="9E84726B9E2B55EF" modified="2024-05-29" version="1">MGNDLSLDTRMERASKTGVLTLSGVKLKNFDSLQSFQLSLLKSLDISDNKLEKFDSIMKKWVNLKLLNASQNKFVDFTLICELPKLENLNVACNKITSIPPQINYLANLKQLNVSNNEILLIPKELGLLSNVVTIDLSKNKIKVIPQEVGNLSSLEEMNFESNLISIVPVELSNLTKIKTFNFNNNDIKTIPKEIYLYTNCIGMELENNPVTRDELSEIPGYEKYISRRKQRVDQFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9A6</accession>
    <name>A0AAD5U9A6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000079">
        <property type="protein sequence ID" value="KAJ3224848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9A6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="307" mass="35488" checksum="FC6586C8F6E82A87" modified="2024-05-29" version="1">MFPNFIPTPLRIISLTITFLIILVPIARIIYQFYKSKKKNILKASQIRYSFIISLGIIVTQTASFIHQFHNYAIEDDNVSLKFNAVETRYSFFRDNNNQFLTIFVTFSLWGTFCLIILMGLDRYSRLDLTLKYSVKYYIAVSVKIFSVFLGISFFIFELFEVTFLAYVSEDSGTLEMQIMRTKMYPIYIVFNVTLTGWYTALDFCLCIKMVKTVINERKLANPFLKKKLILVFIIISLMDVAALVMYSSQTSKALNHISISVANIHFLFSTILLELISSFLIKKNKKIKTVTQLSSVAFTETEQNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9A7</accession>
    <name>A0AAD5U9A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000064">
        <property type="protein sequence ID" value="KAJ3225326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042060425" evidence="2">
        <location>
            <begin position="19"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="201" mass="23243" checksum="F896B0F521BB8CCB" modified="2024-05-29" version="1">MKLLFVLTLLIALAMVASRSYGYKKKHYANPEEVEADEVATLNAGEIEVNPAVNDDKLNEQNVQAFDDDDDEDDEDDDEDDDSGAYGVQAAYGYKKKHYGYKKHHHKNHKYGYKKKHYKSYLDAENADEDDDDDDEGGDDEQELQSQGASYDKYKRKNLIFQFYIFAFTDYGVNLVEHEDCLKALLVQMKWHTIAAWIETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9X9</accession>
    <name>A0AAD5U9X9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9X9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040144">
        <property type="entry name" value="RAP1GDS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10957">
        <property type="entry name" value="RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="823" mass="91362" checksum="ED617F4C2434EAC2" modified="2024-05-29" version="1">MKIAEIFSSNDPSRTLLELIPFSTDDQKDEIFNTTDAIINLISSTLEFNPVPLNKIDLLAKISFLIAECAKDETIRNKYINTKIHLQLGKLMCFCSGHLQPELIIKKQPALTLKRFLPKSVEEENSLNELKIQNMRAFANLCCDNEGNRDLFYETQISIPFLVANLKSSNAKVIQVALGCLLNVSMDNEPIQMDVIEYDGLEILLVLSSQYVGNFSSADYNFELGTGALRILSNLVECEIGAKALLKPIKSFDSNGLKLVTNLIKCHHSNLLSPNCTVEEYKEGVEILELLATILENVGEDVNVQRAIVREDLLDVFLNFVDHIPKDKSCLDNEDEELGEAPTFGAVRKVISKITTLVTMNDENMKDLPHSNSLICRLKNWMGLGHAGDGGEREEDEIRMAAALCIGNLARSDESCEILVKSHNIVENLLNLMHLEMKRLNPESFNISFDSSNEDKKHAKDEIKSIIQVLHAVVGSLRNLSLAANVRNILGEIGVIEAIGELLEKGGIKIAQLGGVTILKNLAKDNLQNCYRIITGEAHNNSSLSTTEAALPTLTNLTPLQKMISLVWKAVEDNDSGIRNEGGRCISNLVRCCHYSKVPKLVNYIIEAKGVPPLIQIVTGAILTKQKTLNTVSHSNISLADVPRLSVGENIDNHVHFDALPVETAVFPNVQNEGIVALILMCSANPHVAFNIIKFYSSLIPTVCKIIQSGINTESIEVARLESTGVNISDITEKTKENFIYPNEIKVNACLLLETLCKAEENFKIKVSSDCLESFSKVDKFNHLKKHEKEKEANLMEIETEESFLDSLSFEIALKQLLKTLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UCD9</accession>
    <name>A0AAD5UCD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UCD9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="216" mass="25139" checksum="A184831B1286C13B" modified="2024-05-29" version="1">MQSLLLTEDTLKCKKQNFQKISLSNKFLSETKQEKIKLVKLVKHKPISEFKIGKQSLHYKTIFSSNIYDEETKFKNKLTPAVDFKKKEVPWCKKVEATLGRKLESSVKIESLKKSKSFFLTDLNNCKTKLMEDSKNFDFKKKNNLFMNEFQVAENESFKEEKANLHFEKERNFLKKNATSAVSGNNTNCSSNHVFSFQYLIKEPPVFNVVNNQVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS17</accession>
    <name>A0AAD5XS17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001416">
        <property type="protein sequence ID" value="KAJ3203532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS17"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964:SF113">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="1">
        <location>
            <begin position="42"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="201" mass="22368" checksum="D5B114987C423E31" modified="2024-05-29" version="1">MSDKNYEDIFEPLTGIYAGDHLLNAEFHLPTLTNLDLIPKEKRLCVAVDSSKHSLAAFEWAYLNLANDGDSLIIIHIFPSDIHMGHSDDLKRQHLDSVQFSLKSECEEIINKLNKVKKVDILTNVKDDICVIASELQAKALVLGTRGLSSIQGLLLGSVSSYCTKHCAIPVCVVPIPQQEKKKLEEDVDRRNSKGLREGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSW1</accession>
    <name>A0AAD5XSW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001072">
        <property type="protein sequence ID" value="KAJ3207206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSW1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="510" mass="58670" checksum="33395CAB63E47F7F" modified="2024-05-29" version="1">MNNSNSIIIKRKANETSHVLKSSELSSNGVILAADAQLLYQKYKSFMEGKMISDNKENFLQIKECHNEKQRAAVDAFNQKYVEAQKKRMNIPPMHKFSGVLKIYSEFQKYQQEVIGICKKVSSKNFIHKLPDVVDSSINNYTKAFQTLANWSKSMQIVNDAAEDDFNKFLKMSLEDVEAPNAFHAAYYSPQIALAIGYEMIKEGTFLGLRNLLYFCLLLTHLNRSFEPIWTLVGDFNFTETLTLQRFQRFNKGKCTLPKKSIVKHSCDCRILAERNNFEAEDYIFVHFNSDKCTPVKGAVVGVNTMRKMLQFVTQKVLGERNMDVSKEENIFSSHSSRQTMGKIYAKEYLGNIDMVKKQLRHSVISKETIKYTGDYGASISEAEFNDWKYLIPPKATFTAWKDFQITFHSQDIDIVEEGEIQQTLEKLKKITFISQSLQSPFLEVFQQNILSMGKFLEVNNISISSIKGNFEAIVQKNFEKTKFCHSFSNGSSTEEVPILDYTKKYKICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT21</accession>
    <name>A0AAD5XT21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000973">
        <property type="protein sequence ID" value="KAJ3208842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT21"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3208842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="511" mass="59278" checksum="561DBE62BC011E19" modified="2024-05-29" version="1">MFAPAQQQQLPPPVFTVQPVSLQPGLPPQYAIVTKEPQFPQQQQPLNLPQTQLQVPQSLDGFSNLSINQQQTNPMSIPQTSQPDSQYIPHQSSFAPVGNGNYGLANTQFNNNQMCVSLMQQQVRPSLNHAIKQNFIQQRGQQQQQMNTAFQHPHFQQNQFPYQLKQPYFSQHQQQQPQQEFNPVWSQQLQQHSNQQPQQQQQPQQQQQPFFSSPNAQYTQNSNTMSQQPPQQDTVEVMANGSVVTVERQPNLNGGQGGQFVQILSQQPQGQQQVQVSPNSTQVIIEPSPANQQFSNSINQNQPTYQIQTQHTTHGYSNNYGNNQRQFQQENEESYFPNFVEKPSKSQRKRQPFKMQLQQQQQKPQSSPHPHVSLSTAERYNQFRNLRQNTSSSESSGEGSSVDGRESVEFEPYSYRDWLTLKQRDGLIQLSAGLGPNIDENHRARQHKSERMAEYSAKISQKHPKQRPNMLKHERHPSQDKLSEREREHHSHEREHHRRHHSNQKQWRDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTT7</accession>
    <name>A0AAD5XTT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007183</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000676">
        <property type="protein sequence ID" value="KAJ3213793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTT7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="9">
        <location>
            <begin position="102"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="134"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="378"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="102"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3213793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="580" mass="66045" checksum="658C7FBA4AA5D2C9" modified="2024-05-29" version="1">MFHKVVKTRSNYIPKPTPGHDNLNNENVKFTNHSISSHNRRYPPLGPSSRVRSSQLQKPNKQGDNLPKLPQRLLLQNKKPRKNEFNFELEQKLNFGNTQKAKSFKELNIDSKIIETLNTLMKYNKPTEVQASAIGLVNEGHDVLIASETGGGKTLAYLIPLIQQLREEENKLMENLDFDLDLPNPLGELRKIKRPRAVIIVPSRELVKQVTTTAKVFSHFSKLRIVGIDSSMKKKQIELKLEEPVDILVTSCGSLLKMMGYDKKTGETIEKTKIYEKFNAKIKSIKTKSVELKLSHCTRVIVDEADSMFDEGFGDELKWIINPLLERREAEKKGGKGRPCQFVFATATLPRQLSQYFNFKFPDLKRVETKLLHKTNPNIKQYFLRVAGNTTKENMLIDIIRRGFISDDVKKVLVFCNTQVSVKKIGHLLREKGFNSEILLSDDVMKERNRKILNFVEVLKLPNTNIDVNKEKIVKDNNENAETNIDTDSEELNSVEDKENFLKSTNILVATDLASRGLNTTKVDHVILYDFPTTAIDYIHRVGRTGRIGRKGVVTSIIAGRDFALADSIKNAIRKKLPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU91</accession>
    <name>A0AAD5XU91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000560">
        <property type="protein sequence ID" value="KAJ3215198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU91"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3215198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="278" mass="30853" checksum="762578F98289304C" modified="2024-05-29" version="1">MQIKHALSTNLGGRSSQQDGYLVIENLYNQPSNFLFAIFDGHGSEGGKAANFAKLHLPELLTKYQKEFEANRCEALKLIFKTLNEMMVEDPSVDTYMSGTTLSILIIFNNKLIVANVGDSRVILGQNEGTTWKYTQLTNDHNCENKVECSRVVEKGARVDRLTAEENEDAGPLRIFKGSLPYPGLVVTRSLGDDVATKLGVLSEPEYYEKDINPTDKFVVVASDGVWDGLSNQEVLDITVKHLEDPVKISKLITKKSVSGMKKKHMDDNTTNIVILLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU99</accession>
    <name>A0AAD5XU99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002274">
        <property type="protein sequence ID" value="KAJ3198742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU99"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="50" mass="6034" checksum="6371DFB059CB5604" modified="2024-05-29" version="1" fragment="single">KHDIANEEYFDLKASFNDMKFTPKVLHNCLKVDRDKDYEDYIAHLINNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUD0</accession>
    <name>A0AAD5XUD0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006301</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000534">
        <property type="protein sequence ID" value="KAJ3215567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUD0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000060">
        <property type="entry name" value="Sensor protein FixL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052994">
        <property type="entry name" value="Tiny_macrocysts_regulators"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31600:SF2">
        <property type="entry name" value="GAMETE ENRICHED GENE 10 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31600">
        <property type="entry name" value="TINY MACROCYSTS PROTEIN B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="576"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="666"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="691"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="748"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="780"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="814"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="471"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="318"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="375"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1103" mass="127627" checksum="8C14305B18BB2A81" modified="2024-05-29" version="1">MDEVRLTSGPEGFRRHQATKVKTILDELLLDSEKIEQNINLGENQIFFKAEKAFHHRQSELELLLLQNRQNEEYNELRNFHEQLLQDRRTRKESKKFQRDLNRDVKLKDVKIHDQEAAHKTAKEVKTMLSEHHARIEELICHIEERHSKQLNQLSISQERRVIDQRIMIDLECRNVSEEKKVELMKEFQFEVNHQRTVDKKVMDQLRDIHSMELRHLKERMEHETISMEEIPNLKATQLALYQKTSFKQRREYLSEKDRCESVIEAQKIMQIQSENAMQVKKLALLHRSQTSHWKKLQKIKAQKRLKLWTMVSSSSNHYNGNNTENNSFNGNSNNNTFLENSTNASITRSDSDESINLNNTEEQNIKNGYDREQYEQNEKNIAKIHMELELLSERHEKALSLLEQQQKFALEEKETSIQRSLAELEYNQDLEFKDLKKRQTAELEELADNYKHELALEAQVRGAETKALQERKILNCLLDNVVDGVVSIDPFGTIKRFNNSAEKMFKYKASDVIEKNIKILMTSEYASHHDDYLYNYLSTGVKKIIGSDRQVTGLKSDGTVFPIQLSISELVDDGLHLFTVLVLFSFSFVFVQSIIQRISFCPNSDIKIDSPESATNVENQAASSGALLEAQTLLETENSLLKMMGSKNKNTLDVSFQNEAHLQQCYSFGFWYFCNWAALAMTYYDMPTLTFPVFWLAFGLLGSVVYTILKYFLDEERKVAEDDDLNPTTTKTVIEEHKMLVLKELPWLTQFLISFVFPAFHTFLFFINISMALSPTQIAYFNGIISYVVFGVFVIFCLYGTTPILSRVEKKNVTVATFGLAVIILIIVTLLYPVFNLNEDIAAGNTLQFFQTLDLKSNTLKAEFYGYKGVRNTLINVPSLKEGLCTNEVSGHFFGLGELGEMCTYNLSPEKTINDIAKLNFDEGTQDNEFFHLGNKSILIKNATYTLITESNLTSFEKALNLSISAIKIPDDQFLILPSPNNGHFTRTYISVKLPKNSQICSIRLNSMNLIHSRIPEWPKNEMNEYSNKYKFIPNNLQSRPYLFEIFTNSPTFFLSVHFTCSYFDLKNFAPLFDEVVDHLDNFGSLINYEGLTVTGSYTLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV36</accession>
    <name>A0AAD5XV36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001350">
        <property type="protein sequence ID" value="KAJ3204023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV36"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DRBM" evidence="1">
        <location>
            <begin position="110"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="682" mass="78191" checksum="22A0A85632186380" modified="2024-05-29" version="1">MGIPNIADFELENILLEIEGTACVQLLAERQAKLKLPVLNYTCEVIRKNNGATSANIVSLFIAGKNFSIEADTKSLGKKLLAPRVYDELKKINAPEINETSKSHYTVMVAEIAKKLRLPPPRYIIHSQNKGNFMMSLWFCDSEFYSEDYFSTKKKAIESCAKEAFVAFKKDYTRRREGLLIAETEFQSSTHIKFDDDTGVLSPSKKTKIDGMVEPKTNIKFFSNYNSKERINQIKNNDTPYLPQHQLPVDVPLHFGPPTFRPPNFGPAANIYNNHHMHTQNQLQQQFPSQSASFNNPNLHSNLPLQGVAVILDHHSSQYNEFAGASKFDSQLPFLNINGIHNNTQNNQIPNSLKLQSAFNILTPVSKKKGIFLKALEAFVEKHNIINIFNFRETSENKFICQLIVGEFELVSKTELSSKFDLMENLAKEGLPKLYEVYEANNSQVLNEELNKAMEVEETVKEVAEDNITVEITEMEDLYGKNWHVKDVDTNICPLRSSKKLKSVNFNEDVMTEDRNAMNEVVETKDRDLLTEFVETKNQNMKNEVNYEINCNKDEEMLSDLSPFEIGSCNNDEDMTSDLTICVEKHRSLNLPQSPNSDMEVYKFESYLELLANLNLELKFNEPQFDFKKVLIKQLDINKEQVYGFKVILEFGYKKFDGKKIYKSFEEGKEDLAGDALKYFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVE2</accession>
    <name>A0AAD5XVE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004771</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000347">
        <property type="protein sequence ID" value="KAJ3219238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVE2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF89">
        <property type="entry name" value="CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="408" mass="46450" checksum="296645566816F382" modified="2024-05-29" version="1">MSEVFGTKLKHPIDGDGMIAALSFSGGKVHLRNKHHEEQTQRYFKFRGQMGTATNDIVSKDALNLATSLATRSKTKLQPFRDPSNTNVFYWGGKLLSSYETMLPHSIDPTNLNTLGPDDLNETLKIPAFSAHFRVDPILKRLVTLSLKPETPSLPGKNGALPILQMNEYDEDWKLMQTQIHNIPGLNYSHDFLLTEHFYVLHMTPFVKTSATLFIQIALGLKSPGDAMKHYPECPSNFVVIERKQNPKVYFFKTGRFHIFHFGNISEVKVSSDEYLLEFNAVCLGDNAIEKFNMSFDQGLWLANGSECPGHLLEFRLTVPLKVNPKKDNGDMKLFDCHQFLAEDSNNEDDGWILVQLYLPEKRKTEFVILDAKCIEKGPICTIRLKHHLPFSFHGTWCEKTFVNQSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVK4</accession>
    <name>A0AAD5XVK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004491</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000319">
        <property type="protein sequence ID" value="KAJ3219967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649:SF11">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="227" mass="25126" checksum="154E779551FD9AEA" modified="2024-05-29" version="1">MVFFLKSQTITIKDYELVLVVVVIFALGLIFGYAVNSLLYVDPAEVLKFAERRKQGLSKKFDDPPNPDSKISDETKLFKSDNLKMVLVVRSDLGMTKVLVIIFFIFFKITLFPALKFSHAAVAVVENLIKQNSEKALSRWSRNGATKVALRLEPSSESELLSIYNKARSSGIPTQYICDAGRTQIAAGSMTVCALGPGISFFSIIANYKFLASASMIDEITGHLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVP1</accession>
    <name>A0AAD5XVP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004356</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000302">
        <property type="protein sequence ID" value="KAJ3220450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVP1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030705">
        <property type="term" value="P:cytoskeleton-dependent intracellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22211">
        <property type="entry name" value="HkD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008636">
        <property type="entry name" value="Hook_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043936">
        <property type="entry name" value="HOOK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947:SF28">
        <property type="entry name" value="GIRDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947">
        <property type="entry name" value="HOOK PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05622">
        <property type="entry name" value="HOOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19047">
        <property type="entry name" value="HOOK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116907">
        <property type="entry name" value="Hook domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HOOK N-terminal" evidence="7">
        <location>
            <begin position="6"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Hook C-terminal" evidence="6">
        <location>
            <begin position="186"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="725"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="176"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="280"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="352"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="435"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="534"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="615"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="725"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="744"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="755" mass="87029" checksum="1B7D301D828C7F20" modified="2024-05-29" version="1">MVEKREAIVSWVNSLVQTKISSITELSDGNAISHILTGMDNKWFKQSQLQNSHSESTVGWVFKFNNLKKLYKLILSYYEEELNLPTSNLIAPNLNAIAKENDEQEIIKFVDIILALVVQCKNNQPFITKIQELESAYQQVLMVAIEQTIQRLNSTSSPVDGKRLSNPDINGKSPQILELEKQNKILKEQIENFKSNTYELSNENKDLKFKLSELENTVNSKSETGQIDFLLKNEISNLKSDLQKSQDKLLESQLLAEKQSSTIVELTKKSEEDHLKALEAVKLKDQLDEFRHLADKLQKSEALIEKYKKKIEDNFDLKKKFKILEDENSMLNSRQFEMENEFKKLNSYKPLMETYKDQIKTLEEKTNVLQVQVSKSDFEIRENKIKVERLEQEKRAAIELSSTLEDRLREIELGGDIGQPNMSLDGELAGDFTSSDSLRQKIVQLERQLEKFKGSNPEDNLEQRIILLENLLEDSNRMKSKFEDDYLSLYQKNLQLENEIKQNASGPQSLQLKLVEKEQIINDLYRKLDKGQEVKENSLETMKLRQQVEELLQKERISEAKLNKLAGEKEQLVENAIELKERVSVEEKKNSDLRAMLAAVESEEAVDGEKRNSKLVEATQKLVQLKQQNEGLHNALKQAKDRILSFEKSIKELKSQPNKENFNEAKISYEALLKEKDLEIQKLILEVKDVRNSCSKESRLISSAFHQLGMKIQQKEIYGISLNGSGTLSGEGSSKNASSWLKSQRKELDNHLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVZ9</accession>
    <name>A0AAD5XVZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_003833</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000258">
        <property type="protein sequence ID" value="KAJ3220996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="283"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="538"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="552"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3220996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="601" mass="66984" checksum="5EB1EE5ACB497076" modified="2024-05-29" version="1">MIEKSVNSITTLASDRQRAATDLPRSHHIATPLQTSLTESKFRAGSKSINNLNGIALPAIEGRHSTTKKPIKSKSIYLSNDQTSNQFLQNNPGSASGLQKKTFLNSLRTLSTTTNSNFNTVNRKSKSAFAHTSDEKTSVYNSTANDESIDVVADLASAALGGSLIFSHSKFNASNSAPNFESDSLGGSLNSLNMKGIVTASKPKSPLPKISNIFVRKGLDSANTKNRSVSEQPSGSTQVLTQKFNNVNINRLSQGPLIDKSSSMSAYEMHKPLQTKTYSLDDFLIFKRVGKGGFASVYLIRLKTGGGKYWALKVIKKTEVVRLKQEKQMLNEKNILKGINHPFIVELFQTFQDQTYLYMVLEYVAGGDLFTYLRKVQKFSEEEATFYVSEVLIALDYLHSKDIIYRDLKPENILLDSTGHIKLADFGFAKIVKHATNSFCGTPDYIAAEIVEGRAYTKSVDWWSLGVLIFELSSGKTPFGDDNSEKIYENIQSGCIKWNSFIKDHCRDIVKSLLTLDHRVRLGSRGGGAEIKAHQWFARINWSKLESRQFTPPFTPTFETPDKLENSKSSSRRDEVLESLKSGASRPTMKNDPLYETFKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW37</accession>
    <name>A0AAD5XW37_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RPN1_1</name>
        <name evidence="11" type="ORF">HK099_001247</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Endoplasmic reticulum membrane</location>
            <topology evidence="2 10">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the OST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001330">
        <property type="protein sequence ID" value="KAJ3204177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW37"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007676">
        <property type="entry name" value="Ribophorin_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049">
        <property type="entry name" value="RIBOPHORIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04597">
        <property type="entry name" value="Ribophorin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041783811" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1" evidence="10">
        <location>
            <begin position="28"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3204177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="410" mass="46994" checksum="14C85D93AD431F39" modified="2024-05-29" version="1" fragment="single">MKISIKNLNFFLLSVLSFITLFDQVLSKKKDLNAVPITIQQHYINTDVQRFIDLTCASIVRSKINLKIKKSSTNSGKENFPYYFALPSELSELKLASFQVFLSKQSFDDKNQVNTVVEKDAIDAKSGVQYFKLTFPDNFKVEDSFLKVKIAFTNLLKPFPKSVEQIPKTSQTGSRQLLLFNGFAHFWSPYLTENQKTTIRLPKSHIESYTASPKPVTKTDKALTYGPYRDVSAITSPESTDRIKIHFEHPHAILVAKTHERIVEVSHWSGKLGVEDHIDLHHNGAKIKGHYSNIDYRLTQHMQVDTNVVKSIPLVLPANAVDVYFKDTIGNVSTTNFRNEKKRSLLEFRPRYPLYGGWKYSWFYGYSVPISQFLKSNKNKYEISVDFYDSMHNITVEKAILKISLPEGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWT3</accession>
    <name>A0AAD5XWT3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutathione hydrolase</fullName>
            <ecNumber evidence="6">2.3.2.2</ecNumber>
            <ecNumber evidence="6">3.4.19.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Gamma-glutamyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Gamma-glutamyltranspeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008612</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="6"/>
    <dbReference type="EC" id="3.4.19.13" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000968">
        <property type="protein sequence ID" value="KAJ3208940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWT3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000554">
        <property type="entry name" value="Ribosomal_eS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047861">
        <property type="entry name" value="Ribosomal_eS7_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF9">
        <property type="entry name" value="RE13973P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01251">
        <property type="entry name" value="Ribosomal_S7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00948">
        <property type="entry name" value="RIBOSOMAL_S7E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="536"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="560"/>
            <end position="562"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="584"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="612"/>
            <end position="613"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="635"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3208940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="644" mass="71689" checksum="7B3B8396EEB74BD7" modified="2024-05-29" version="1">MSARSKIVKPLGQEPDSLELQVAQNILDLEHNVADLKADLRGLQFISAKEIDVGHGKKAIVIFVPVPSLKQFHKVQSRLIRELEKKFSDRHVLLIAQRRIMGKPTRNSRVKQQRPRSRTLTSVHEKLLEDLVYPTEIVGKRTRVKVDGIATYSALPFGKQVYLGDDLKLGKWKGDIAVQSNICHKIAKNILEIGGNAVDAAISAGLCSGVINAYASGIGGGAFMLIQPSKLGNVNKNYTLLYDEFGVLFEKDDPVMIDCREKAPEKSTFDMFLSETEAIGGLAVGVPGELHCFEVAHKKWGVLSWYRLFEDSIKLAKDGFVVPLNLANRIEVFRSTIFKDELLKEVYAPDGKNLLKVGEICKRTRLALTLEKIAKEGISALYSGDIAESVLRTINNNGGIMKIKDIRDYRPTLRRPLIQNFRNKFKVITTQAPSSGPLILSMLNLLERFNVTEPDEEGYHLQIEAIKFGKAQKTILGDPSFDKSIFETVTRIIDKNTGKRNAAKINLNKTFNSKYYANDFENEDNTFFSQIQEHGTSHISVLTKSGPNNENFEAVALTTTINSPFGAQLVDSNSGIILNNQMDDFSKPYTNDSLGNPSNPRNFPKPFAKPQSSMTPTIIQNLESDHITVIGASGGMYCSKRFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWU3</accession>
    <name>A0AAD5XWU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000595">
        <property type="protein sequence ID" value="KAJ3214740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWU3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="212" mass="24497" checksum="9DB0221DD36D957B" modified="2024-05-29" version="1">MLDNVDQLEPGYYFLSDSRNIYDVKESKHYTLYILENLSTAASFVDFKLSGEIKNVKLNQKAYFRDPVVFDPPIVRSTITLKLITTIKSASQTLEENLNSHLFVFSNGDRWSSTVIKNKYCEGFKKFMHFNIDFSTNRQLMVYFAKVNNIKLWQGSKEGNLAEEQNEEVGFDIQANHSASSAKIHYGKRRADPFINIVWVDDYTKGVEFSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX38</accession>
    <name>A0AAD5XX38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ERG9</name>
        <name evidence="3" type="ORF">HK099_006220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000522">
        <property type="protein sequence ID" value="KAJ3215756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX38"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045338">
        <property type="term" value="P:farnesyl diphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000023">
        <property type="entry name" value="Squalene synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006449">
        <property type="entry name" value="Squal_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01559">
        <property type="entry name" value="squal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626:SF2">
        <property type="entry name" value="SQUALENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="448" mass="51441" checksum="3C0B86ED52390D31" modified="2024-05-29" version="1">MASTLLSSLFHPQELHALIKFKLTSPTQFSYASPNDIPFEKGDKEYSKAKTYYFLNLTSRSFTRVIQELHEELRHPICIFYLVLRGLDTVEDDLSIDYEEKVKILTNFHGYIYQEGWTYNGNADSEKDKPLLVEFNYVIEEFLKLKDIYKTVIANITKRMGSGMAEFRHPDRKVVTIKDYNLYTHFVAGLVGIGLTALFVNSGLEKNPKLILAAPENSLHYNSKVKLDSADQENLPNRMGLFLQKINIIKDFMEDLEQGRVFWPEEIWKAYVEEGEDLKSLALVENRSRALAVLNHLWEGTTVFKFAAIPQIMAMASLNLFFNNSLIFGKKPLKIRRGTSAHLIINCCEDIETLKKTYQKFIYELHKKNHDAIGKNSFDKSFVKIAVNLGSIQRWINIHTMQRYSSSGGDLGTLKALELSSNTQRGCLDYLLVIITAVAAWYILNIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXW0</accession>
    <name>A0AAD5XXW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXW0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="180" mass="19802" checksum="FC9612CEE886AFAC" modified="2024-05-29" version="1">MVIGRLFIRLQEIAVINPVTNVVWMTLFPVAKFNPAAATDVHPRAPVKLSESISFPVGLNSFAEFPFLVDLCFITSLNTSSMNSVTAKGSVSIQTSTYIKGIHECKKSSLTTFQKMGTIDKLNKHRRSVRHPIRAPLLSFKEKSTIVASTVLGIDFLTLRKVNVSDTETAATVGKNIHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXX7</accession>
    <name>A0AAD5XXX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TSR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXX7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21250">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="22478" checksum="1E4B3201B4561595" modified="2024-05-29" version="1">MAIQHHANVVNICIPMVNLIFDFFVQHFLIVPNVNDENIIPTNDIRTTCRTMRFNSIQQKTYLYENILEFFKKHSRNVEPHELARNFEDFFDEIFSLSLEDNSQYQIGTLLCKLYNEIFFSNSLEELTKLRNWSSMKKSGTVKIVNNEGESTDDDSDESLVDEEMLVVKEKSKIEPVIDDDGFELVQKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY48</accession>
    <name>A0AAD5XY48_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Kinesin-like protein Klp8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KLP8</name>
        <name evidence="12" type="ORF">HK099_006588</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000167">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022164">
        <property type="entry name" value="Kinesin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032405">
        <property type="entry name" value="Kinesin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12473">
        <property type="entry name" value="DUF3694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16183">
        <property type="entry name" value="Kinesin_assoc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="11">
        <location>
            <begin position="1"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="1485"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="66"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3225554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1601" mass="182994" checksum="92FE162E432859F4" modified="2024-05-29" version="1">MTKYDITLINPKAKETKHFCFDRCFNSSNKSDANFYTNQETLYDEVGKEVLDHSFQGFNTCLFAYGQTGSGKSYTMMGTENDVGVIPRFCKDLFKKIENFKTADLNHSFSVSASYMEIYNEKVIDLLNPFPNNKKKLRIREHPNFGPYVEDLSKVLVNSHSEITLLIENGNKSRTIATTNMNQNSSRSHTIFTIVLLHHYDNKETGMLSEKQSRICLVDLAGSERTNLTGSTGIRFKEGTNINKSLTTLGKVINNLTEDKNSGKKSHIPYRDSVLTWLLKDNLGGNSKTVMLASISPAAIHYDETISTLRYAERAKRIINKAVVNEDPNIRMVRELKEEVNRLKEVISSFTAPPADRSALELELAGISLDEVSMLRDQLNTSEKLMKELLLSYEEKLEQTKVLKREREIALHNAGVTSIGFLSTLHLPHLVNLNEDPLLSECLVYNVGEGVTNVVHVQSDNASSFIENRIEISGEYIMPLHCFFQSIKFDCEPPQYSVSLVPTKDALVFVNGVLITEATPLYHGDRIILGDHHVYRFVQPNAASNKFRRDSIISQSATQNSGTSSTNSYYSDTSSNKRIIDWNYAVEELNKVNMESGNIERFFKSPRRSLFSDDDVSSICTSTYDSVIDDTIFIDNDCFPNSFQQDCEATSPIFSSPNVFSQKTLRSRRSMLQINNRSQINRKLSFLSLDADANITDCSTDRFLQNLERKAHIKRLILSQIHSNFYDYLVETILSFLPLLKEANVIALEGKKKVVYNFCIVHRSMAYNFVEGSFWDGKKELERRFFPNFSDVPQVKVKVFDARHNSLYYWSLSTFKEKVQVMRQVFNAEPNKVDDNLNFCEIFYESVQNRPSFQPIGFSKLFKFNLFAHIPREGKLPVFEANGAEVLGYIRILLNPVPFSKSISNSKCVDSRCYEISIIELNGISENFFTQVHVQFKYFNQKSKKMEFCSTDLTKNFGNKTIKFDFFKVVSLVDEDIVFEIFGKPIKLVENVIEQELLNPDLISERSMSFSAETFDLSDNCKLDFQKHDVLVQMSILELSADSGKFNCIPYKISEKSGDDGEFFLKQGVQRRISVKLSHVSGREFPWRCVKSISLGNIRTVPNSKKNEVTRSNLPNLNKSAESMDNLISLKVPTQQIIESQRNGNTSIQVTLPWDSSLHENINLNRITATGEKIYIDIFIEADLEPLPPYSSSSDDNDNKKSREVGPVKFNFCFGVNVISRNSKINTNLHSSKLFTFLNSFGAPTNSLTRPRYKNVKSLIFAVFVKLKKNKSKLDLNKGYVRGEEILHGWPKFPLEIIEEYFLVKKKLTKKFQVEETKQYLQFKEFDDVDKCNTTAKNGEGYVDDGKKKINDVLLKDTSFLPGFNAQIEVLKNYECVENYPSCRDISDFSLRDTKSKTTAEDQINEIDLNAKNANIFAKRSDLILVKKVFELWNKESKQNIFNFCSANATGNQDVKAPVWEIKSQKIELSSNLICGSGWLNTPLGEQEESFDEKKKESATERWIKRYCVLQRPYFHIYESSDQVNGQLLSIPLSEVTVQFSIELWKTLQRPYTFALYTTSPGFSTIFQAASEQDMFFWISIIDPLYYSAMISSKNNKIKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY98</accession>
    <name>A0AAD5XY98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006388</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000547">
        <property type="protein sequence ID" value="KAJ3215388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY98"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16650">
        <property type="entry name" value="SP-RING_PIAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="SP-RING-type" evidence="8">
        <location>
            <begin position="957"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="384"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1111"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1142" mass="129472" checksum="8AB2E234F6AB0A19" modified="2024-05-29" version="1">MDEDKELNSLKENCRKAGNLYFNSKAQLDQKLEEIAILQKEVNRYKEVYTTLKNAVEVKKDEKLKKLDVLLLSPQSSQNVNNLNSFKPVTQNLGVSEGQTDSFLNTNTTQLNLQKYNYKNQTEDASSLLQNLKNYNQNITGNTGNYSNKNFYNTASDTTKKNINNMNNIGNFSPTINDEYNQTLDNKRLNNFSHTYSNQNAGNTLKINQHTPVRPTQNLEFKKKSPRDCITFLEDVISFLKKDANYFEVCCEEVIKFYKAQEEAYSPELTPMMKEFIKIAFVSASKCNNSRPLKKVIAQIYTKVEKMDTEFIAFFNSLSNEPKVFLPSNAAQRQTSQPANTQLQYLLPHQMYQLPIGYHFQGHHLPFGQQQQIRPLYQVPQSLNSNQNQQVQHSSREHLQPNSNQAINPSYPFATGATLQHQHTQKSQTDTFDSTDKSNTCDYQCSLCGVNFSTKEKLNAHIKQKCAPNIDIGADQNAVSTSSKDEVSHLTQNSTNSTPNVIVNTNNPLESVSLPNKSNGQQQMVSGAFPQNQNQASSTLHNVSIESIQHSSIVASVPENLNSFSTQVYNRIPPVSITPMQTSTKTAVTTAPHITQKKSLVAGTLSSEISPPTEASQVSKLTTSIKSGSADLQLEPLIIYDKSSQEYTAIEKEATPEIVDLNLEESMDSIEKDSISKLTRRSSKDTINKITKTPIAVEPIPLPFESSSDKEKTNLMFTTVLNQKFDADNTMNSTRDTIKNPVPIINERRNIINNATDPYEGKFIANNIGSAERNVIESEKVIKLKTITEYTSLPTKGLIHLMGNLRNKTSLNHLIFRFPFSDDGIKFLNANSNYIAKLCIYDYPKEAKEEIKFISVEVNCVNIVLKKSYLFSHEDKGSKIYFEGDIPKNCLTQENIVRISNTIGGSDRAFCKILMYGEIDFDSLLYKIKHDSRLDAGSTIRKINDKITQMNITSESSNRNHEELSIRFSLMDPISKKKIGYPVRGFMCQHLECFDLKSWYDQQLKTPNSICPICSNPIIPLSLKKLNQENLINFNLIFDEYFNYVLESDVVKNLKENSNVMIDAFGDKKFKIVDNINDRKRISIDLTETNTSKKVKLDSVKVVSNFTSENLEFNTKDRKIKEKNLDELTKEVNWLESDTDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYK2</accession>
    <name>A0AAD5XYK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYK2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="770" mass="88712" checksum="B7700C9C2DBE445E" modified="2024-05-29" version="1">MSRRSRRSIATAACSTEENFTTNKKIKLKSKHARDFEENVIKSILSYLQPFSMKSAEFVSFLSYGSVSKRWQKVLFESSQWTVLGGIVENPVLWGFNSIENYLYETFFYKEVKKLKKHPLKSLKQFCKILTLISKPTQDKWWEDLIFERNYSGWSLDFVNSDMVSFLPTAKKNFKIKTLNDIISKANTILIHHDFSIFEIPHFFEILSQLTLQLLISFPQPNQIKKIYLCTRLNKSVIQSLCSRFKNLTSLNLQQHSEDDTLTDETLDIISKTLDFSNLKHFGLSQLGENCSIAGIFGCLKSLGSTLITLELKDLKSVSGTVDLSLIVLLCPRLEGLRLINLFVHKSLKGLKFLSDLELRDLESPEVFVFKGDDTFYEPVYIEEDHTSVTSLANNLPTISMYYMSPTYCLMQHIQAFLPISHNNWYETDNESENSFNFHESDIMPERFDETSPMDHIRKDGSLRRMSESILLSDISGEPVGTSSSSNISEVNFSTLNFPAAKEFSLVETCLQLGDESLSRLKRLCLWLNPNSLISTSEDSHRDLRPHNGKVKNCFPETWGQLKCLELVSKCTNLESLHLSYCYFSGSIQDWCGISNKNKLDEDAVNNRNDPSHRKINSEDAVELFSSKIVLDEADMQQILKGADMSLVWEFENIPPNMLKRYKKSVGVLRTFNNKLKHLQVEYDIERCKYSLKHMEPIVTDRIKLPFLQSLRIDVYLQGFIELDAGRTGLADFIVQDRYGRKSFEYLVTKWYENRPDDYWKLGSDKISGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYM1</accession>
    <name>A0AAD5XYM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">T-complex protein 1 subunit zeta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">CCT-zeta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CCT6A</name>
        <name evidence="12" type="ORF">HK099_007198</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000679">
        <property type="protein sequence ID" value="KAJ3213751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYM1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03342">
        <property type="entry name" value="TCP1_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000038">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000058">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000004">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012722">
        <property type="entry name" value="Chap_CCT_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02347">
        <property type="entry name" value="chap_CCT_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3213751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="524" mass="57425" checksum="734B7132868EEA8B" modified="2024-05-29" version="1">MSANAVSLANPNAEVAKSGLALSININAGLGLSDVVRTNLGPKGTIKMLVSGAGDIKTTKDGKVLLNEMQIQNPTASMIARAATAQDDVTGDGTTSNVLLIGEMLKQAERYLSEGLHPRVITEGFEIAKKEALLFLEGFKIKREMDRETLVSVARTSLRTKVRPEVADALTNAVVDAVMCIHQKDVPIDLHMVEIMKMQHKNETDTRLVKGLVMDHGARHPDMKKRVENCFVLTLNVSLEYEKSSAEQREKLVESERKFVDARLQKLVDLKKSVCDGTDKGFLIVNQKGIDPLSLDVLAKNGIVALRRAKRRNMERLQLCCGGTAQNSVDDLNPSVLGYAGLVYEHVLGEEKFTFIEDVEKPKSVTILITGPNPHSIEQIKDAVRDGLRSVKNAIEDDHLVPGAGAFQVALYRHLIQFKNGVKGRPRMGVQAFADSLLIIPKVLAQNGGFDAQDVIVSLEEEQAAGHIVGLDLQTGETLDPVTEGIWDNYRVHRHLLHSCTVIASNLLLVDEMMRAGRSSLKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYS4</accession>
    <name>A0AAD5XYS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD repeat-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">WDR4</name>
        <name evidence="9" type="ORF">HK099_003645</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat TRM82 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3227022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106004">
        <property type="term" value="P:tRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03056">
        <property type="entry name" value="TRM82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028884">
        <property type="entry name" value="Trm82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16288:SF0">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16288">
        <property type="entry name" value="WD40 REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 6 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="184"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="391"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="428" mass="48343" checksum="0BD05D373DC2FC27" modified="2024-05-29" version="1">MISPFHKILSSKKNKKIILVYTSNLLVVDSSNGEILAASSEKSSESNKSYFKIESSLFPSSNIRSIALSEDESELALISEDKQIANWNLTTYSRTGETQSIKRANAVQYSRDGTSIAIADKFGDLYVLKKNKLNQNSIRLHLGHVSMLLDFTFSIDGKHIITCERDEKIRVSNFPNSFIIDCYCLGHKEYVNSIHIPRFATDMLISGGGDALLILWKFKTGKEIDRFDIAAHLEKLEVDNNAINKFYTTVMEIKSYSNSNCIAVVLEKQPFLLLLRLVEDKLTFMQKINVPKDILSMDFDSEGNIWMCFGAVSFKSEDTGNNLVAISRFNKEKNLYSAINVDDPLTSKINNFGTTTVDNFPDYYEVSQLGKSSIKAKLEINAEKFNKNKEMDKIKKMNKKGAKNCNTAEDGTNSEENDLQQVKKQKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYU0</accession>
    <name>A0AAD5XYU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYU0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042077550" evidence="2">
        <location>
            <begin position="25"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="103" mass="11798" checksum="6438E53DA7C666F9" modified="2024-05-29" version="1">MKLNYKIILLALSFFLIVSTAKLAKNLEEQAAHWTVKCNSMLELDNMKNNGPRKNQDEMQIITAKEIFIQEINDELYWNGVHAWSVLISAALSLITGIMILIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYZ4</accession>
    <name>A0AAD5XYZ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003965</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYZ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF99">
        <property type="entry name" value="RASGEF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="562"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="733"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1047" mass="118446" checksum="5F880960976BE12A" modified="2024-05-29" version="1">MDFYSILCYFKLTSFISESYMEKLSKNNCQICNSTERFHTTPSFPCTNLANCEYCVPCEICSLSNNEKSSHSELQSLPLNDSILNCSLPLNDSILNSDDSLATPLRDTIPRVGRKKKTSSVIGLIGLNDVPSNTTEKKELQSVAGTLANSKRYRRAQSGLSETKNLAKISPVFNRPRAITDETLLESKLQALKVETDPRSQATVEVGGNTGAKLATDEIIEPERISSTVQIIKEVIEGQPVDRNSAIRSSWGRKGGMHASMELLTEKKITKRTTLIFESRNNSSENFPDASIRNSVKIESKLSNVISLTSPPSLINILKDKHNMNEINLVQNTSASNLASLQNTNNSPSNESVLRKNSQESVIPGNQRNSTFSLKSSKNKFSKSFDQLFQKKIKPFTSEILNDGGSPAANSDLSTVNHSSLSTSPAVLNSVNSNETFHMLKKDQNNSNSGNKLISSATRSNQFIIGAENVNPTANNLATFPPDISLKVIFGSKLASNRTISQLLWAAKCYENVKTEAIWNENVKEADSSTDDVTDEIKYRILNIFSDGRITELEYKHDIEEQCDFVKAGKPLDLLDALIFPLDQDATFAEAFLATYRFFIPSEKVLDSLLEWYNVDLYEDCLSSEELFLKRNRKLIQKRSIKVILMWIKNYWLDFVLSKKLFQDLNFFVESLSLTSFGDNQKLSQAIREQRLSWYTTLYIPAFPLKKKKIPQQLPDVLTITAPTKKTLALTIEAIDLAKQLTLIDHFFFRQIKPDSYLHLLEINFSKTEGGKNSALKVVLEYVEWFKMISTYTCSVILREETTKKRISALKQFIRTAKELRSLQNYNTFFAVMSGIKRPAIIGLQPVWEQIPLKYIDAFQTMDNLLVFDEEMGYTTYNSEFKLAEPPAIPFFAAYMQDVIEIYDGLPTFTDDLVKAESNKNNNQKDFSKQNSMNLNCLQKDAFSRTLDDDDPLLQKTINFEKFYNLSNLIIKHERFRKVNFQLEIKEPGTTNGINPNMQNATVASQLSTAASLMQNSQENAGNFLKHLREFINSNNFEESRLDDLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZI0</accession>
    <name>A0AAD5XZI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005603</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000444">
        <property type="protein sequence ID" value="KAJ3217090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21678">
        <property type="entry name" value="SMP_TCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052455">
        <property type="entry name" value="Tricalbin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980:SF2">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="9">
        <location>
            <begin position="233"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="423"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="623"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="741"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1159"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3217090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1476" mass="166797" checksum="E28BED1AEF0086F4" modified="2024-05-29" version="1">MNDVEEYHETAESLNEKLGNDTPEVYSQDQLNNLQKLKKQVSDKIQHAIKNIRMQAGSGGRVSEVDVMEKPNRMSMAGLLSAVFAAKKLKYPLKDNSLIELKAKAAKAKVDERLKFTGYLFNYNSLYELPSQLNDSYVITPMSDEKLCEQLKVIRPVFGELIYWENLTSALVWSLSMFIVWFLARFNFSPVWLVILIFYVGGSMKRNNQLLISKLGRSVKEELADNKLKEADFKEEVEWFNTFLSKYWANYEPGLSAQIQESINFYLRLYKPTFLEDMLFTTFSLGSEAPRIENIRILPKTEEETIFMDVAVSFIPFDEETKPLTLNKKQSKLELKLFIGKGGMTVAIPTIVKNVSLVGTMQASITLSKTFPHIKFVDICFKEIPVVNFDLRPLKGLDLMDLPGLNNSLYQLIKDQLKANIVDPVKIHLPLEEWAGALPIVDKPIGVLKLIIYQAKDLKNRENIGQSDPYTKFILGDKVLGRTKAVHNNLNPKWGSEHFIIIYESFVDPANNDSLYFEIFDENEATKDKSMGRTSTLKLSHWIKLAEIPPPKVEGEEEVNNNEKIDNREFDGLSTEEANILKKDWGLPFDSTTDLWKPIFFAKHEEKVPKGELKLNLLYFPLPKAESFSVKNENEDIESGIVTITVHQVKDMAESLKATNMCVVCELNTGEEVGRTEVVRKSSTPVWDKSFDIFVKDVEGAKVKLNVLNNDHLTGNCILDVSDILDNGSQSNDWYKLKGIPSGKVRVTVKFVPVDLEAQHFTKSTPSHFIRICIREANGLKNVEMMSKSDPYCSVTLGNQDLGRTCTIEDNLNPTWRETFNVIACTGTQLLTLLISDFNGISKDKILGHTSIRLQDLVDFNSINKYLSEVLSVDVVEPTREVLKSSTCLEEDQKEKETLAKLKNDGLQITSFTPTFIEVLSPLYRNSKKAAEVVKGNINFTLEVFPIIQNKVIKADRKSKKKRSVLEEADTKKSEEVSKKTENTVIDSLEKNKILTDEAPEKNSAETFNESLANVGEFERVKLVVEKFRAGILNFKILDARDLDKTRSFYCVLETQEYTDPGAKITHSARAAKYSTKVVHDSVNPSWNEAGEIFVSDVRTNVVRLAIKYLHNHNEKKSEQDKVYAVWNGKGENLLKLIGQAKTWLNLDPSHDTYLASDVHPAVRVSVSFYPVFMEDESNYETGELQLEILEGSEIDSEGRNGHCNPLVVVKRNSEEVFKTKCVKKTSNPIFHETVNLTIDSKMKTSLKFEVFDHRTLHKDESLGYFDLALRSLPSNESVLKDFKLLGGSGRIKTRMFFSSNATESQSKKNSRDIDSFGHNFISDKTEQQNVVDKELVLSQLPQKQSDIGDSLPPVVAANTNERNIRQKKFSTTSAEDSLNVVGEGTLKIIEARNLKGADSNGLSDHNLFKESTEIGESHELDVLDLLYPNKSALNEAAHSNKMEVNKHFDTWLPIGDGCGEVHLSGDFCLNLSSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZW3</accession>
    <name>A0AAD5XZW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyltransferase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000274">
        <property type="protein sequence ID" value="KAJ3220776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050879">
        <property type="entry name" value="Acyltransferase_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028">
        <property type="entry name" value="ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23028:SF134">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="656"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="682"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="40"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase 3" evidence="2">
        <location>
            <begin position="501"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="777" mass="90406" checksum="7EB56626C1A99C7B" modified="2024-05-29" version="1">MKFLFKEKEETKALLTDKDKVKIELIEDVTTKPTPSPRFHYFDGLRGWASLQVYASHNYAQSFPGNLTYSETLFKNILLGKRFHIPFFFVLSGRLIALSLLKRPTLPNFTSTCFRRVVRLGFPLYGGFFLYWLFGAVGFYKEYVLSPELKSSKIASLNHFKFNPWNGGGEWSTFSRTFFGTSQLFQFHNVSYPMQGVIWTLYVEFFNSYFIYLVAILASQCTGWGKIIIYSIVQFYTLFSFSVEPHSPEGNVGYFVGGLIIAELANAGFYKWVNKQRFWWIIHLALFFLPICSILPNQADYWENIINNHIYKSILMTKGKTVIKNNWLNDRKVWFRVDLFRYLMGTSVVTLLELNSFVKGFFSTKIMNWLGMASYGLYLLHPIWTSIMYGRLIPFVDCFFHSWSKLTQAGVLWVANLITMIPVLILFYHVFDNGSIFLGNLLYSVFTEAMYLYIRNLISCCFASKKKGGENKEALLYDNDDDKNLKKDITTTKLSSSPRFHFFDGLRGWASLQVYAAHNFNQTFVKLNGGSFLVRLFKNILIGKRYHVPYFFVLSGRLIALSLLKRPTLPNFTSTCVRRVLRLGFPLFGGFFIFWMYGVLGFYKINELSPELKKHSQLTYLNHFKENPWVTHTEWHNLSRVFYGTTQLPHTPDGNVAYFVGGLIIAELANAGFYKWVNSSRWWWIAHALLLFLPICSVIPEVQPIVEDYVNNGIYRQIIMTKGSEIIKNNWVKDRQIFGWYFPNNASRVKFTNPWIFQYEGHAMARNGQLWLVSDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZY4</accession>
    <name>A0AAD5XZY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000118">
        <property type="protein sequence ID" value="KAJ3223765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="31"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="131"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="416" mass="49308" checksum="90DEB2981B4FE101" modified="2024-05-29" version="1">MNTIKHLQRLNFQTKPENKIDFHLHQCRLFTDIVFESKNEKFFLHKCQLFAFASIVKFLNIICTKINEAEYLVKDDYSTNFKKAIQTIYSNTITLEQKLKILNETFHLHLLILQEDLDLEARFEFQMNDYTDCLIVTGGVNQYISVNKFYLSQYPFFRILFTSNFGDSTTNKFNFTNEFKDDELNLKNLFLNFTFKGEINPTLLSNTKVKTLIQFYKLGNFLGSDEICYFINWYFYNIFCLCSHCIRNSLKILKFLHHNTLIDSRQNNFFDLKNIYMKILTKKIRLSAILENKTFISEISSYKGSFFSLELKNKKDGEKNFVALLYIIERQDKELRIDIGSLLFDLIFFELNSLTPGNIIKRYIAISRVKCENKGWQASIQFVLRGEMEFLIVNNFEFIYSSALDFKLQLLDHGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y049</accession>
    <name>A0AAD5Y049_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000336">
        <property type="protein sequence ID" value="KAJ3219522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y049"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13493" checksum="020EB34CC4AA1896" modified="2024-05-29" version="1">MENFNPQHPAAHGVARLTLELKVEFIEWQNGCMLDYCSLMFNCPLAVEKVFDIQRGKLMEFSDGESGARMHVACIKEGGVDLDLSDGGKVTSLQALDSGFTDPIVSGRSIPCDIRNRQPYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0J4</accession>
    <name>A0AAD5Y0J4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LicD/FKTN/FKRP nucleotidyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002854</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000199">
        <property type="protein sequence ID" value="KAJ3221954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0J4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009100">
        <property type="term" value="P:glycoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009644">
        <property type="entry name" value="FKTN/MNN4/W02B3.4-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD/FKTN/FKRP_NTP_transf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407">
        <property type="entry name" value="FUKUTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407:SF28">
        <property type="entry name" value="RIBITOL-5-PHOSPHATE TRANSFERASE FKTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="5">
        <location>
            <begin position="86"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="170" mass="20806" checksum="2BDC902BC4666869" modified="2024-05-29" version="1">MNISNFNNYDPKQENYLKLSWDLFEKFETDINFDLTNLEDQPKYYQILKEDTHRDSRFSFRSINPAERIQTLRGILKNWVEFNQDIGIVTWINHGPLLGWYWNKQLFPWDADLDFQISPHHYEILKKYNQTIINENYLVDLNPYYLDRRAWGFNVIDGRFENFLFSFPFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1H9</accession>
    <name>A0AAD5Y1H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000171">
        <property type="protein sequence ID" value="KAJ3222530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2601" mass="272281" checksum="2D738316B9D48099" modified="2024-05-29" version="1">MAIEVDNNRLDTSTPTTNDAVFVVSQPESSTQQKKRYCWGKLSKIQFVITITLLTFIFIVALGFAIGFLVILPNFVPKIVYHFLFESDLKELHINSLSVHKVDDKGIYLGADVDTPWKLPISFADAELQPMTLSFKSEKNNEDLFDIAVRDKIYMNGWDKTHLALNNVDILVKNPTNMGVFLNNLGTWLLSENATVENAPDRLVITGTGSSKVLGMMVNNCNFNRVQNLEFIAKLMAKGAFAGFNFNALNTELGALGGEKSDSAIAAGPVLIDQIDVNVDAKGISVKADGHFVKRSPINLEFGKINVGINLGSEAQLASVASLQVNGIKLSEHDPNFKLDVSLIPKIGDAQIVSKAVGSLLAGQYDGIYAGVSDIFIQGPNNVVIPWLDTALSQINIKVPLKSFQEKLMTMSNPSSAGSLLGDLAINDLSVAMAVNNTINIQPNITIPAFLKAKVNVMPFTAAISDDNGVKLIDLSLGAISLTGSGPQTLAPPIKLVLNPAPEAAAALGKVGQNLISVQPAYLSVGKIEFQSLAGKADNLSGLNQMFSVLRIRIPLLKLVDKSPGPKFLIAPGNSKATENDAKALPPKILLSLIGGGISATGNSIIIKLDSTLASLLPVQASIPYLALRLGLDKIEDAVKVELTGLALKKGSHALNNTLEITFGSNNQLPPKFANIINSFLKKEEIKTDIVIGGLRFGPSKPDSYGLLDNLNIVIKPITLKTLTAVLAAPPAPGAVPKAPLFKFNLPPSIADFKADAIATTLNPVLQSLDISTEASKSLKLGTSLSFTNPFPLSLDVPYVGLDLSIDGDKLLRVGIAGLKAEKSSPNTNQIVVTLGFVDSFPSATITKVVGNIKAGNGIKGLGLGIKGIALGLDPSKSIKALSELEVKVGSNGPSLDFAKMVPWLTKDLLQKFQLAVASVEVNAVANGLQVVAGVNLNNVAPLTVNIGVLNLGVSLTSTKLVTVGISNIKIVRGPQLAALSASVTFGRDAALKEKVKDLVDKVLNKRLALIEIGGISLGHSANDRITAFEQLTLPFPLPELNLGSLGGSSGGSSGLLKMLNKADVTAVPDGLNVALGINFAGAPFNVVVRNLYVSLDVFLQNARILGVSINNINMSAGRAAQVLNLPIGLAISKDPSVARSLAGLINPIFQGRPANLALAIRGLKFGSSPSNMFDFASLAELSFQLPLPAMDVKSLFNKGSSSQSGGITSLLKKVDVTAVAKGLNVGLGLAFPGVGFELNVHSLFLSVDLFMEKVRLVQVALDNLNVAAKDAQILALAIAVNFAPEASNAAQTVATYLNPILAGRPDVLPLSITGLRFGSSHATMLDLLSLIEIPLPLDPSSLLSGISGGGAGKPGLKDLLKKVDVTAVPKGLSVGLALDNLNIAAKDAQILALAIALDFAPEAADAAQTVATYVNPILAGKPSKLPLSISGLRFGSSPSTMLNLLSLVKIPLPLDPSSLLSGISGGGAGKPGLKDLLKKVDVTAVPKGLSVGLGLAFPGVGFELNVRSLFLSVELFMEKVRLVHVALDNLNIAAKDAQILALAIALDFAPEAADAAQTVATYVNPILAGKPSKLPLSISGLRFGSSPSTMLNLLSLVKIPLPLDPSSLLSGISGGGAGKPGLKDLLKKVDVTAVPKGLSVGLGLAFPGVGFELNVRSLFLSVELFMQNVRLVDVGIDNINITAKDPQVLALPVAVNFAPEAEKIAETVANAVNPILAGNGGTIPLTISGLRFGSSAAAMFNFLSLVKVPLPVNPGNILSGIGGSTPEGGLMSLLRKLDVTAVPKGLSVGLGLAFPGVGFELNLKSLFVSLDVLLDKIRLVQIGLDNVNVNATGAQVLSLPFALNFAPEAQNVAQNVAGIVNPIFAKLTNNTVLPVGISGLRFGSSPETMFNLLSLVRVPLPVNVKPILDKLGGSSGGPGLDFKKILALIKSVDVATVESGIKLGLGVALPGVGFELNLKSFFFEIEIILNRIRLLQIALANVNVAAKDAQILTLPIGLNLAPEDPKIAEMVAAVVQPIINGDFSKTFFAGIKGLKFGSSKSTLFTLFSLIEINLPIKSEIFQTIGGGATESALALPKITSLTGGFLPDVSMEVNVGLQLTTPLPFAVTANIGYLGVDIQFGAYKVATLSVSGTTVNGAGAIGTSLKVAFYNNAENELEARSFVSCFIAPLLGPGAGCENHRINIKNIRIGHTSSQNFVFLSLLSKELLVDIRDVLKLASGGSSGSAIGFTNGDITLSETGVSIAGDLTLNLDFNVNLNLGYLNLLLIHNTGLSTGTAGSPTTMLVNVVVENLVISNSSPQRIGATINMGTTPYWQEIAGSLLKKVDIPMSYALYNFRFGKDAASAVTLFSKVPIFVPYIQQILKKLAKPDAPKKPLPFGALFSGEEEFGFMLTYLLEGQYSTVLLHVWNAATFNINLGQVSINILDALPTGLFSRIHPVRVGNYVNNYIPEQKLNLLSQEGCSSNCNRTSSIAIMLGPSGVIGSDVIKDKPAGTPGFDGDWFQSLLEPYLSGGLSGVLDLAKTLVIDSPAISNCPWVTDSFKNFRIPIAGFLPAGGSGNARTAVNNSTATVTSASAASSATSNVIPTATASAIARKVRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1I4</accession>
    <name>A0AAD5Y1I4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Prenylcysteine lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003129</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prenylcysteine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1I4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001735">
        <property type="term" value="F:prenylcysteine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030327">
        <property type="term" value="P:prenylated protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030328">
        <property type="term" value="P:prenylcysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010795">
        <property type="entry name" value="Prenylcys_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017046">
        <property type="entry name" value="Prenylcysteine_Oxase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944">
        <property type="entry name" value="FARNESYLCYSTEINE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944:SF0">
        <property type="entry name" value="PRENYLCYSTEINE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07156">
        <property type="entry name" value="Prenylcys_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Prenylcysteine lyase" evidence="8">
        <location>
            <begin position="85"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="413" mass="47130" checksum="DBBA5C9B54370D8F" modified="2024-05-29" version="1">MHSNYVDCQNFVKDCENKSFLVELGASLFAEKNYNLVNISRDLNISYSNEKEINSEKNGGLGVWDGAEWKIRFVDGSSSSWYDGILGKAKMIWRYKMGLFSGKTLAFDLAEKFFHIYDYLNNDNHYLFVEDILSNLNLTWTVESTAKDFFLKKGVNENFVDEIIGGLVRNTYGQYVDKITAFGGLISLYSAVGEVYSSKNGNMNIFKEMLEVSKNVNLKLNSKVITVEKKTESGEFIVTTADNKTTVFDIVVVATPLNKVKFDNIALPIQQVEYVTVHTTIVIGKLNLNYFKLKDYKELPESILIPSSADCPFNSFSIKTWINGTDAAIVKFFSPKKLEKSLLEQIFVGTQQVYRRSIEAYPKLELKNLNKWKTPFQLTEGLFYVNGMEEWISTMETESLSGLNIVNYLKNKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1S8</accession>
    <name>A0AAD5Y1S8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Coiled-coil domain-containing protein 38</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CCDC38</name>
        <name evidence="5" type="ORF">HK099_000049</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1S8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051147">
        <property type="entry name" value="CFAP_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025252">
        <property type="entry name" value="DUF4200"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683:SF3">
        <property type="entry name" value="CILIA AND FLAGELLA ASSOCIATED PROTEIN 100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13863">
        <property type="entry name" value="DUF4200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4200" evidence="4">
        <location>
            <begin position="143"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="350"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="484"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="532" mass="61926" checksum="680EA51102022DE6" modified="2024-05-29" version="1">MGVEVAASPLAANTCKKPKKFTAPILSSPRDKLLRLPEISKHQVKPQPIEVVKENPFHMPPDQGVFAMREGEKKIKQELKEKMKNLKIHEKNVEKRKNFKSLLSEDLDDVEFYEKMKKKDSEKILVNKHAQDRHFTKENLHDFIGKKREMFLVQYALGVKRQEMQKLEEIAQAEEQTLLDDEKALEEDAAKFDAFLKENDKNSVEAIKRAEMETKGKLEKIQEIKKLNVNIMNVRSEMSKNEEQLKDLQRYRKFLDKLTPSDASKKELETSKKAAAVSKALQKSLPQQKSTKLNKISKNRQVNNAEKEEPEEEEAEGSEEVQEDIEELWSDVGEEPLLYFNSPQQLLDIFSELEENNLSLIQNCQETEETLEDLKQKIVETESKMEAETQSLKQQIEFLNAAIVKEEEKAKALEERSKLFSSGLVGAESQERLLEELNHKVKEVYRRCIGDSDANLNTLQMLTNIENKLENLFEDIELMPPDKVEQAEKLKDKERRQRLREEKMDAQRILQEERVQRALERARAPVKKKVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSJ4</accession>
    <name>A0AAD5TSJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002100">
        <property type="protein sequence ID" value="KAJ3199498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSJ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="185" mass="21551" checksum="1B2A9EE154565EB1" modified="2024-05-29" version="1" fragment="single">MSSTLPIYHEENFQITWQKILSGPNFNETFIDNFLTLFPVSIQINKNNLLPNSSLSSEKTFCQQTKKKTCKQKLKKIEKNENLFKFTSKNIFKSKNNLNLNSTLQTLQLENEQEEEIDKFNSKEEEEKVSFEFLQCKDILNFIQKNSLLCSNKINNIPKEPTTLSAAEVSTITKLKLIQNYLNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSM8</accession>
    <name>A0AAD5TSM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002988</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002028">
        <property type="protein sequence ID" value="KAJ3199828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="86" mass="9959" checksum="140CB2ED032DBFD6" modified="2024-05-29" version="1" fragment="single">MRSTKTKSSKEMKTLHTTFIGEDRYNKEKTNPGLTPVSELMFFCKGFGRSKPTTQKQRIINEKSLQLDSKLNIIDHNEQRNTESLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT38</accession>
    <name>A0AAD5TT38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dual specificity protein phosphatase 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DUSP23</name>
        <name evidence="6" type="ORF">HK099_002705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001919">
        <property type="protein sequence ID" value="KAJ3200374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT38"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000157">
        <property type="entry name" value="Protein-tyrosine phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057023">
        <property type="entry name" value="PTP-SAK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22784">
        <property type="entry name" value="PTP-SAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="56"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="151"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3200374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="374" mass="43198" checksum="F711977DD8D34F03" modified="2024-05-29" version="1">MNIKAVCPQQHPTQSNLPPTPPDSFTEQFSFLINNNNWLQGRDPYNYPSDPNLPWHFSWIDDGMIGGSSAPTARFHWKAMKDANVGLVVNLTETPIFPKDLSTSSIYCDNCDFIEEQFDDDLFDDIQSDDEIETLFLPVPDGNIPRYEQLDIFLEEAKKTIRKGKKVVVHCQAGVGRTGTFLAVYLLDKNKCLPSEALSNLRYVRPQSLQFDKVDWQSEPFKFSQPDNYSRNFVQERYIEIYYQNKILPFLKNKQNNDNKKPDVYESDIELELGPYLLNLIDDEIKKKFNFFAINPPIDIEENKKTNTQNNCYSCLNILSIGPLKVSKDMRYFSPFFDDTLKDNQDQISIDSITAYGYQSLDLNFESLDVCEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT39</accession>
    <name>A0AAD5TT39_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001770">
        <property type="protein sequence ID" value="KAJ3201177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT39"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="375"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3201177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="434" mass="49781" checksum="C22D9A9BCF36C196" modified="2024-05-29" version="1">MEAKKINKGYFKEKHFDDKESSLERVTNKAQKSQKVKNVVNRGEPISTEIAIGEIFQNTSYNQQPSDTKDTILTQNNYSDVFTNHNTDHLRETQHHHLHQPNSTHLNSSNQDEIFTNYEISNWSSQQVNYSTTAQKSGLNLHEFNETSQESLEIHMLELEMLGGGNQHHNHSSNGMDGNSTSILNPHAKRQPSDMTLFEVDQQQQTYPKNFNPINDISAFSSNPIGYSSSNWSNGYETSNYLDSATLHQSTTPTLQHQCGYNSDFYSADQQQHGISPSLLNLYPEDASRPLNFPPSYTQANPNLPQIYAPIQQDFQFQRLQQNNAASNNAKSAVNLRYSNLTKKIKKNNSVKPEKVPIIQDSLPSGQHFKRMLFKEKAIVKLNDLITENNKLKREVEQARILREKENMESNFYLETLDWLMTDLNKKHSPLQMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTG8</accession>
    <name>A0AAD5TTG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001808">
        <property type="protein sequence ID" value="KAJ3200945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTG8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="66" mass="7042" checksum="64D7E0CA006CA1D0" modified="2024-05-29" version="1" fragment="single">MSISVKGYSVGILGISIISGSILNSTKPDSLFLRSVNNTNSNLSSPFQRSTAATHSPHQQFIIALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTU5</accession>
    <name>A0AAD5TTU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="8">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_001901</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010001593">
        <property type="protein sequence ID" value="KAJ3202283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTU5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038066">
        <property type="term" value="P:p38MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000341">
        <property type="entry name" value="MAP kinase kinase PBS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF25">
        <property type="entry name" value="MAP KINASE KINASE PBS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="68"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3202283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="336" mass="37546" checksum="A3F190783762C89A" modified="2024-05-29" version="1" fragment="single">MSKLSLRLGKNSMMSLTNLGASNGSTFSTFSKYIDMSGKLNFTGKAILSAEGVDFSNGSSYHIKKDEFEIIEEIGKGQYGIVQKVHHKPTNVIMAMKEIKLELTQTKLNQILMELDVLHKSVSPYIVEFYGAFFIESSVFYCMEYMDAGSIDKLYEGGIEEPVLAKITLSMVKGLKFLKEELSVIHRDVKPTNVLVNMKGEVKLCDFGVSGQLIQSLAKTNIGCQSYMAPERISVKEAGSYSSASDVWSLGLSIVEMSLGSYPYPSDLYDSVFAQLNAIVSGDPPKLNEKRFGRECRDFVNSCLYKNPVERPTYADLLNHNWLTTWNDLEVDMVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU37</accession>
    <name>A0AAD5TU37_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001284</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001348">
        <property type="protein sequence ID" value="KAJ3204048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU37"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="95"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3204048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="24205" checksum="72D0E149DEF006B9" modified="2024-05-29" version="1">MINLYCSIKSCGEANYIAAHKAGLIGTKIHPVLVNLQNHIIVTGPKKGSDFFQVNPKGNVPTLVLEDKTVLNENGSTFLYISDLNPESGLAPPVNSIERYEFISLLSFLSSELHQSVAELFWVTKGSLKEFCLKRAKDKLSYVEKELVNNEKKFLFQDKFTALDAYLIVILSWTAPLGIEIEDNYPNLENYRDNLQNMDYIKAAQADIQTLSLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUF1</accession>
    <name>A0AAD5TUF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000741</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001189">
        <property type="protein sequence ID" value="KAJ3205631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUF1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3205631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="298" mass="33522" checksum="E4B563453B4A288E" modified="2024-05-29" version="1">MLSAHSPNFVYKTYETLLPTNNHPTSHSIEETNFSSLKNEWWNYSWAANNDPDSVDIQYIEIDNAKKNLIITPPETPQVVGKCIHGSQSLKCEECSKLNKCPHGRKVNIKVLLLKDKRIFFSQVVVKDVVVHQTVNITAKGQFAELAKVAQFVNMGREEVIAVNAVNSGGTSICEHDRRRYECRQCNGKGICEHQRVRSTCKECGGSRICPHRKLKQTCKECCGSSICQHMKYRSSCKVCLATDTNCIHGKERVICELGCSTKINDIKSKTLVSFDTSNLNIQDTKVESDNINLTTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUU9</accession>
    <name>A0AAD5TUU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001243">
        <property type="protein sequence ID" value="KAJ3205009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUU9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="166" mass="19370" checksum="D6E5750A10AED6E0" modified="2024-05-29" version="1">MQNSDDNINDLKSILNDLKKHELNEADLKLTFNEFQFDFSINDSAAKNFFIQECTLDSISTLQNNLEKITEIEKKFNNLKNMYEKEKIALINENLKELNKRKLIISTSKIPFSSKSIYRLEKNFFNKIETDLTLLQVERFKTLFKFIAENANTKSNLLSPSIDSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV35</accession>
    <name>A0AAD5TV35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Coiled-coil domain-containing protein 61</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CCDC61</name>
        <name evidence="1" type="ORF">HK099_000692</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001171">
        <property type="protein sequence ID" value="KAJ3205853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV35"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22284">
        <property type="entry name" value="HD_CCDC61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049733">
        <property type="entry name" value="CCDC61_N"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3205853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="22579" checksum="607A05A66DC3B270" modified="2024-05-29" version="1" fragment="single">MEASVEFHGTEYNLSINYSIDHEHQDDYLYLKLFPKNNKQRIYHSKFSPQYIEEMTRKTGNFKSFAIFVEMLISSMDKTSNSVFLDLLSNQDLEEMKKQSNAFINYNRKTQDITSNKKIYLILTYAIAFDRIHYPLPLSLGNSSIKNENFNFQQQNVVNNFKINDNSSELLNSQIMELQSDRQKLMKEQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV57</accession>
    <name>A0AAD5TV57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001156">
        <property type="protein sequence ID" value="KAJ3206056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV57"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3206056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="398" mass="45982" checksum="9E4085AE57E6D118" modified="2024-05-29" version="1">MNLQLMQNSSSSMILNIPDFSVETLNGYLDCIKDALIVCQLCIDNKLSLFEQRPANSQLLIKSGSIFVYNNKSGIKRWIDGKLWSPSKIVGGKFLVYKELSSKMKRKTKFKGEGEKGIICSKGIYQPKENGFLKKTITIKINENDSYHLVSYYKKIDVKSGILLPIALHQRYNYVDINFNFVEKKKERKKGLKGKDKAARDLTFNESRDENVSEENDKESLGVNCLNLAVKANFFDILTFNENSIFNSNDDDIFLSNLENENFSALFKNSNIEKVCYDFDNPHYFKIKDKATYKEKTVKLTSNEENFVNEKCLFDDNEVNQIVNDFNSIDHSNKLNYGIENIFYNQKKKIFDSPKESKPNNDQFDFSKKRIDSGFISDYCFPNVDESENLFLLNSDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVD0</accession>
    <name>A0AAD5TVD0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Malate synthase</fullName>
            <ecNumber evidence="2 8">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ACU9</name>
        <name evidence="12" type="ORF">HK099_000198</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the malate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2 8"/>
    <dbReference type="EMBL" id="JADGJW010001032">
        <property type="protein sequence ID" value="KAJ3207787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVD0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1220.12:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.360:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="entry name" value="Malate synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="entry name" value="Malate synthase, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048355">
        <property type="entry name" value="MS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048356">
        <property type="entry name" value="MS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902:SF1">
        <property type="entry name" value="MALATE SYNTHASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20659">
        <property type="entry name" value="MS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20656">
        <property type="entry name" value="MS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="MS_TIM-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="Malate synthase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Malate synthase N-terminal" evidence="10">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase TIM barrel" evidence="9">
        <location>
            <begin position="152"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase C-terminal" evidence="11">
        <location>
            <begin position="404"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3207787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="526" mass="59665" checksum="AF03663DB2D5E1D7" modified="2024-05-29" version="1">MQNAAGVSVNVSAEYKQLLNPSAQQFLATLHRCFNQTRINLLNERVKKQEKIQNGWLPTFNPDTKYIRDDPTWTAAKPAPVEITGPVSRKMVINALNSGASTFMADFEDSTAPTWENILEGQVNLIDANKKTISFHDKKSGKSYSLNEKIATLLVRPRGWHMVEKHFLVDGEPISASLFDFGLYFFHNVHQTLKNGLGPYFYLPKMESHLEARLWNDVFNVAQDMLNIPRGTIRGTVLIETILASFEMDEIIYELRDHSSGLNCGRWDYIFSFIKKFKHDPKFVLPQRADITMTTPFMDAYVKLLIKTCHKRGVHAMGGMAAQIPIKNNPEANSKAMEKVKKDKLREVTAGHDGTWVAHPDLVKIALEIFNKHMPQPNQLYKQYPEIEVKASDLLNYRVVGGKITYDGLVANVQVSLLYLQAWLLGNGCVPIHNLMEDAATAEISRSQLYQWVKHGSKTDDGKVVTRDLVNKIIDEQVKELEKSAKPGVYDKPAGFLKRMVVDYPEFITTTLYDSFKGFALPKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVF5</accession>
    <name>A0AAD5TVF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RNA-binding protein 8A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_000128</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001011">
        <property type="protein sequence ID" value="KAJ3208132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVF5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12324">
        <property type="entry name" value="RRM_RBM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000525">
        <property type="entry name" value="RNA-binding protein 8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008111">
        <property type="entry name" value="RNA-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033744">
        <property type="entry name" value="RRM_RBM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45894">
        <property type="entry name" value="RNA-BINDING PROTEIN 8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01738">
        <property type="entry name" value="RNABINDINGM8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="75"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00077711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3208132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="174" mass="19110" checksum="BA53A251132B0EE8" modified="2024-05-29" version="1">MAKNDEFEIQLDLDNADGEEVEEMIVDEDNSKPSKRKGRGFNNDNARGSEFANSGKFESLKDEGVGRAQKSVEGWIVLITGVHEEATEDDVKEKFAEFGDIKNIHLNLNRRTGYVKGYALIEYESASEAKAAIEEGNGTELLGQTVSCDFAFIKGPNTATSITSRLGARDGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVF8</accession>
    <name>A0AAD5TVF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S1/P1 Nuclease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003248</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002155">
        <property type="protein sequence ID" value="KAJ3199253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVF8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042244430" description="S1/P1 Nuclease" evidence="8">
        <location>
            <begin position="19"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3199253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="34870" checksum="AE212CEDB1F6021B" modified="2024-05-29" version="1">MFKLVTLFVLCALTSAWGWQGHDSVVLVAKEFFDPMTIKYTDLLLKDSKYDIVKSSTWADVVKNALPWSKPSHYANSDEKHVDNNGTCGKFSDENQTDPLFNIIAAITNYTERADCHRRQPLDFTQRLEALKFLLHYVGDITQPLHVCGRNKGGNDDKVTFGNKKTNLHAVWDSNIIEKRISEISQNTTNEQHVRDYGKYLAKQLRGRQGVYADADSWVSSIRTKFNKFNSRKSWVVPIEWAQDSNGIDCTVVWPSYLEDPTQDLSLKYYEDAKYIIDLQIAKAGYRLATLLNKLYYACRRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVT5</accession>
    <name>A0AAD5TVT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Hydroxyacid-oxoacid transhydrogenase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ADHFE1</name>
        <name evidence="10" type="ORF">HK099_008442</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate</text>
            <dbReference type="Rhea" id="RHEA:23048"/>
            <dbReference type="ChEBI" id="CHEBI:11047"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:24734"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16724"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="EC" id="1.1.99.24"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000927">
        <property type="protein sequence ID" value="KAJ3209689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVT5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047988">
        <property type="term" value="F:hydroxyacid-oxoacid transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08190">
        <property type="entry name" value="HOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1970:FF:000003">
        <property type="entry name" value="Alcohol dehydrogenase, iron-containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1090.10:FF:000003">
        <property type="entry name" value="Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1090.10">
        <property type="entry name" value="Dehydroquinate synthase-like - alpha domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056798">
        <property type="entry name" value="ADH_Fe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042157">
        <property type="entry name" value="HOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496:SF83">
        <property type="entry name" value="HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25137">
        <property type="entry name" value="ADH_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56796">
        <property type="entry name" value="Dehydroquinate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Alcohol dehydrogenase iron-type/glycerol dehydrogenase GldA" evidence="8">
        <location>
            <begin position="55"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-containing alcohol dehydrogenase-like C-terminal" evidence="9">
        <location>
            <begin position="276"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3209689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="470" mass="51286" checksum="94E83F36BBB22FDA" modified="2024-05-29" version="1">MVNQLQSVLHLMKNIGSHCPCHSPALPTHSLKDLHRRSSQSTKTYEYAFEMATSSIRYGSGVTKEVGMDLQNMKAKKVAVFTDKNISKLLPFTTVIDSLSKANVNFVVFDQVRVEPTDSSLLDAIAFARFEQVDTFVAVGGGSVIDTAKAANLYLCHPENQFLDFVNSPIGKGLPINKKLKPLIAIPTTAGTGSETTGVSIFDYEARNYKTGIANRALKPTLGLIDPLNTKSMPPTVHVSSGLDVLCHSLESYTAIPYNLRSPRPTNPLDRPAYQGSNPISDVWSLKALEMCVKNLESAYKNPENPYPQEQMILAATFAGVGFGNAGVHLCHGMSYPISGLNKSYLHKGYEGVAKKLVPHGISVAVTAPAVFKFTAQACPERHLQCAKIFGVDISQKKKEDAGIILSDAIKNFLYKLDVPNGIKAFGFGAQDVEKLVEGTLPQHRVTKLSPEVIDKEKLARLFEDSITIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW19</accession>
    <name>A0AAD5TW19_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000943">
        <property type="protein sequence ID" value="KAJ3209385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW19"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="699"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="767" mass="86638" checksum="65EAB445379599FD" modified="2024-05-29" version="1">MKNLGKPCRIFDDIAKCTGDFDSYLSEKFSNKAVDTFSKFRMFQLLDSTILDISVVFPRQKFEIYSNYSPEEATEENYLKEIGPLRCFLNSKGNDNLTEILNQYSADQKNMSKELITTRPDNNCISSSYIFRHALVTDAMSESNSFESILIKYGGCCFLCSEETGFFFPTEAIAGQLTSYSDSQASFDEYDNGNGNDSSHRSNNGASGHEAEMELLSENEDDHGQHHNNFRYRRQGSENYSVTNPDPSDTNRDTEDEELRNDETVTLNVRKRLRRRSVQLRGTSSDLEVDPKKLSRSDSCPLSNKPDSKTRNLSINSSKKKRRFTDFAGEHSKTDAEEHTDFEQDDRFLDGSNHSKKSNNDKDCESIDCTKDYVRNRAENDNDPQDKEVEYEGEDDDENSGHKKGVGAESKDDSKNVAKKMRRTGSSIAGGDETRDEDFEKGTLPSNKTITGNGGGVNNYKIQQLKQKSIEILNKNSEALHFLPSLPHHSPYVSHPPYNTASAPQHSSSIPQHIPKQLDYAGPRPFKFGGDLLNQQGKPLLGKITKTRPNGYPPALSAQPPPSTFPTRSAPTSQQQQYPLHPGCEVSARYNHQSQSSSNPNYRGEVDPRTHYSQSGNPSQTSNYEYHREPLSHNGRPHQSSRYPNHPPPNAIPPTSSSVHSNSQPEYDHRYAAYEDPYHYFQNHNYSYHQHGLPHSGYHSQHVPSQQPAPSQPQQHTVPPHHIGSSGNSYPPRGDYFYQHPSPHLGRCERCGSEFDPRYSKSGRYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW93</accession>
    <name>A0AAD5TW93_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pescadillo homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Nucleolar protein 7 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">NOP7</name>
        <name evidence="7" type="ORF">HK099_008177</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pescadillo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000873">
        <property type="protein sequence ID" value="KAJ3210789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW93"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17709">
        <property type="entry name" value="BRCT_pescadillo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03028">
        <property type="entry name" value="Pescadillo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010613">
        <property type="entry name" value="PES"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221">
        <property type="entry name" value="PESCADILLO - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221:SF6">
        <property type="entry name" value="PESCADILLO HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06732">
        <property type="entry name" value="Pescadillo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="374"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="519"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="656"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="539"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="580"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="616"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="663"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3210789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="678" mass="77672" checksum="F75F2A70089C7807" modified="2024-05-29" version="1">MEAGALGTVIRYKYAGSAATNYVNRNQALKKLQLSLAAFRRLCILKGIYPREPKNKKKAGKGSTAPRTYYYKKDIQYLLHEPLVQKYRDYKTYQNKLKKAVLRKEWSVAKSLEANKKPDFRLDHIIKERYPTFIDALRDLDDALSMIFLFSTLPSLDRIVVSKIRECQRLAAEFQAYVANTKSLRKVFVSIKGIYYQAEIRGQEITWIVPHQFTQNVPQTVDFKIMATFLDLYLSLVGFVNFKLYSDENFVYPPKIDIEKDGHGAGLNAFILESTSAQYEILNRVKDHGDVANQKAETKKQSKSSVKQNQKQAMSKLPEKLKLLADQEEEVEELGDDEEELDQSIGIDAVDDDSDDKVDLSAPNLVAAFQSLNQFKNLFKGCYFWLSREVPRHSLEFVLKSFGAEVGWEDNLDDSKSSSPYNVTDSRITHHIVDRPLPPNGVKPSWVVDDRRDYIQPQWVFDCVNAQKLLKTKSYHPGDVLPAHLSPFVKYESGDYVPEDAKRLFGISAVAVSKGIDEGSMEALNDKDEEENGDKSESENEDSSESDDDDDLENEEGSDEELYEEELKAEAAGLTYSEYMQKKDSEKKEDKKDNKRKRIEVAPKGSTVTKKVKKSKKEEMENEEKKELAKMMMPKKDKRLYQQIQFGKDKKAVEVAKLEKKRDAHKKNNKKGKSPVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWC5</accession>
    <name>A0AAD5TWC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000749">
        <property type="protein sequence ID" value="KAJ3213075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWC5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="1">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="404" mass="46420" checksum="D9E8234166E93995" modified="2024-05-29" version="1">MLRFPTLQVHIDQQQILITNDLDSPPQVLTGYVTLHLFKPISPNKISVVFHGHESISIPAFDVVTYHRIIKLKQTLWKKGTGDIEPFLSGNRIGNTIEPGIHVWPFFFEIPNNLKFPTVSALHGDLYYQCTAILNRSKSLKQNLKASEEVKVTYQCWRPPLHSGSFSVATIQDNTTLNEFNYKIIIPPILSKQDLNLKANIILSNGNKDVDSIIGISCYISEKQMYKFETALESEGNWTETVLLSKAVKFKTIKSEHSKFEKDQRQSLGEFLKTSLKLNDSKELIFPLYTTKNTNVDTVTKCFEISHFLNFEIEYENETKTFTSLNKRRFSEIFLLKKSSDSFFNDDSDEETFKKNIPSSTKNLRRSSFFDTMGKKLTQFKEYKIEKRTVSISVPIIIVGAIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXC6</accession>
    <name>A0AAD5TXC6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000656">
        <property type="protein sequence ID" value="KAJ3214029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXC6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="263" mass="29919" checksum="2C1204B335A40E13" modified="2024-05-29" version="1">MVMDNYDIKPSKPFCVLELGSKNKQEEIVEKYKDLVSNLNFDSDWYNYPEEKIISELLTDFENLKNCFELMNPRKITELSTRICLSSKDCHKNKWMIVRLAKKYPSFNVEQVLLFHMEIAEKCNPEEHTSILLSSIQQQMLRVEENITQSIKKSSESLSSNILDTGNNISQSITDVKEIGGTVLKAVESNDKTLLSSLTTTENNLSQLIRNSNTITDAHLGSFSSKLIATENIILQNLKTDLSQLCSSVQKVDHNITLTSFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXE4</accession>
    <name>A0AAD5TXE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000689">
        <property type="protein sequence ID" value="KAJ3213664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXE4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="197" mass="21961" checksum="CEF20BDE746675A5" modified="2024-05-29" version="1">MAMVLPGSYQHSVIKILKYVIAIISVMIVLCQYVVMYIGRNAKSFAREVFLNWTNLAALLAILGYTLYIITNFFLNFRMILLIFSSGGEKKKLEGRVKLKLISCMTLTSLLNLLALFVFYSGDSFAAAHIAVSFSCTDFLISTVFLEIIGYAHNKIKRKRLGPKVVEAEVSILSSVPSQLPSSDLKLASRDQDSSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXI0</accession>
    <name>A0AAD5TXI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AP-3 complex subunit mu-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AP3M2</name>
        <name evidence="6" type="ORF">HK099_002613</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001886">
        <property type="protein sequence ID" value="KAJ3200524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXI0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="5">
        <location>
            <begin position="134"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3200524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="299" mass="33556" checksum="0A158536FE1CB828" modified="2024-05-29" version="1" fragment="single">MISQPVYHHENFTSIHILKHGVYFIGITTDEANPLSLFQLVHLIINILHSYLLQISENTIKQHFDIVYELLDEIVDNGSPFITDLNTLKIMIPPPSILNTVINAVSLGTSYGPKTPTPSVSMVYWRHNDIKYTSNEIFLDVNEELDVILKNKGELITADIRGEIVCNSRLSGMPEIKLSFTNPNIFEDEFCSFHPCVRTFIFKKDRVVSFIPPDGLFKLMDYLIPIASAGSLPLIVKPSLNFNKTDGKVEITILTKNLSGSGNKKILENVAVVFKLPSTTLSVKLTANLGQVHFDQQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXN9</accession>
    <name>A0AAD5TXN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000636">
        <property type="protein sequence ID" value="KAJ3214269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXN9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="371" mass="43681" checksum="4C74EF34862C7D68" modified="2024-05-29" version="1" fragment="single">MTVINRFLPHIIKYKKTISYSNQEIKNIQQIAIYASRMFETNYLVNVQEHFIQKVKKFTSTMIIKNLKFKGISKEYIKLLQERNRKVQDYIFGNVNINISNLYDLQIANEIKELLPIDIHKEGLAYDIVARTEKYLEPYFKLCELYKKYDLKVFNFTPLSTSSIPRHITIDTKILMENILDFRRTKENTVKSEKEFVWSTIFKTDTKAFRSRNNMSFNGMIRTDGVSICVLLSSPKPKKDDIPRVKKRKKPEKTEYFQDNLSDLRCNKVFIDPNKRDLLYCLGSNGEKLKVLCISPLIIVSSWSIELNLQQALFSAHLKSHLNILLDSLDSMTDFNSNFLTDNFAFTQMQRRKESGLKRYRIIREKVSSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXV4</accession>
    <name>A0AAD5TXV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein root UVB sensitive/RUS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006793</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000608">
        <property type="protein sequence ID" value="KAJ3214581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXV4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006968">
        <property type="entry name" value="RUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770:SF31">
        <property type="entry name" value="RUS FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770">
        <property type="entry name" value="RUS1 FAMILY PROTEIN C16ORF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="6">
        <location>
            <begin position="56"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="6">
        <location>
            <begin position="124"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3214581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="297" mass="33432" checksum="9D77BC7057C987C5" modified="2024-05-29" version="1">MLYKLKVRDSKAQVEVRSYFLDDDKLCVAEPLNQSFSIKKVLFDIFLPNDFPASVTTNQASLAAIGVGDSTSTTTAAMLTWIFKEGSGMVGKLIFAYKVSDILDKEAKKFRLLADIFNDLSRNTFSSLCGVSAGGTKAALSLHFARCNNLGDLSAKDDTQNLNEIFCLFSSQNYFITFGLNRNCLHLKKIQIVFNSHHTVKDITRSIYQSILIKNLVLTNDYSQMKDLEILESTLKKTFSPEFAQFFDLLMAENSKPNTKYGLSNSFEKWNLDIAIFKSFLGCDKWVVDGWNATKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYE5</accession>
    <name>A0AAD5TYE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Iron-sulfur assembly protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ISA1</name>
        <name evidence="4" type="ORF">HK099_000099</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001004">
        <property type="protein sequence ID" value="KAJ3208249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYE5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050322">
        <property type="entry name" value="Fe-S_cluster_asmbl/transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072:SF41">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="3">
        <location>
            <begin position="20"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="846"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1022"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1114"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="851"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1022"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1114"/>
            <end position="1126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3208249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1153" mass="128666" checksum="93B4046024D98904" modified="2024-05-29" version="1">MNILIHKATFATRKNLKLVLKMTPNAVSRLKELQVDGNKILKIGTKKKGCSGQSYTLDYVTEFKKFDEVVEQDGVKVVIDSKALFTIIGSEMDFVKDELSSQFVFNNPNVKEVNAIFLEGFVLRWARNTNDSISTLHLTNATSNTISKQIQLPYEIKQLALINQAKIVLISNNSLALTYTLQSLERVSFESFFFNYEKENFTFPFDNPFKYNVLENSLINPKVARDTPVHGSFLYLNATLNSSQNRPCVLHYIFDEFNTLTQSCKAFSGITEANPLLDLLYLPSDDNNTATKFLLPTSKNAYQVEIDDNYIPNSFFNLTFTTNTKLYYASNNSVIFSSNSDCGLLRTVGSNTTVWHDVNRGGEVLGVTERGFYMCSNATTFLYLLTENGTTLDLSSKFEVKNCISQILYIDNDNLALITPTNITLLYTNFSSTNHFPTFDTLWSKKLTNSSFSTISQGNPAFYKNDKDINFYFNNGDLVTGPFLRLNSFETPDTTETSVPPSSSERKNITQVSTGLAIPITLLIIFTLIFCCVQRYSKRKNKSENDTVLPKISGTATPTPDFDISGSTKISSDRAYSPTFEPSDVDITSNSLKKNASNETVSIAVMLSNSQINLPDSEITAKKNDQKETLNSNIKSTSSDIFSNVESNVTTLVNDNKLGNDKDLTKSKTVVQGMMLVENHNSADVGNLEYSNLKNEVDKLNLKNDLTGSNGEIVKKNNNHDADKTQINHTRDSLEFKEPLEFNNQRNSTTSSQLQQILTKNRPTSPLSYNSSRGYEASFEGGSSFHDSVSVSETSNRNSVDNFSLNSNNTIRPDDAVLINNYFEKNFSELPKEKDLQSLFIGEKKAEETSYETANSESSHYQKPTTSKPSVYDLSSDNLNSLSNDLHIDHSDISSEVVNMHKYQEMSSQNGSSASEIKSRILKQVVNSDIDVQQSSGELFLTADESSMKKDYSANDSSAYVTANEASGSKFFNKQFVESDSNYESAMEYTTENTVRKDLVEIEEVSEEEDIEYHGRVKTKKNYGSQVGSSHTNSELGSQDGSDIEYKGRIKVKKSSRAGSELGLDDIEYKGRVKGRRINSIHSKVSNSDTGEYIGKIKAIRKVEYNGKVLSKRNSIQSNGTSSVKNSSKDEDSKPNSIDGTEYIGSVKTKVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYF2</accession>
    <name>A0AAD5TYF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bud22 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006258</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000529">
        <property type="protein sequence ID" value="KAJ3215657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYF2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037393">
        <property type="entry name" value="Bud22/SRFB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015158">
        <property type="entry name" value="Bud22_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23325">
        <property type="entry name" value="SERUM RESPONSE FACTOR-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23325:SF1">
        <property type="entry name" value="SERUM RESPONSE FACTOR-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09073">
        <property type="entry name" value="BUD22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bud22" evidence="3">
        <location>
            <begin position="225"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="419" mass="47842" checksum="DBEA1302CAD784B0" modified="2024-05-29" version="1" fragment="single">FHLHKEVTKSLKKAKKFLSLKMIRQLKELKLKDTENQNCMNAQISKITQEIETLKKINLPCIAKSELIEILTNSELPEKELCLNAVKNFNSSECIESDGNIHKSLIEKLIKQKCVQDELNSCLKDLIFLITGKGEKKPKKERIRKKDFQVLDNDELLAKISKIKVSSNTSNIAAQNIADVNKAGIKKNNSEKVLEIDLKTFEPNNANEKKLIDSSEIDYSDFENYSDVDDEADIEAEPEVPKKNRKGQRERRVEWEKKYGKSAKHLLKIEQKKQELESLHPSWKAKKAQAPVIKDFVGKKITFGDDVTEESFTVQNTNNNHSIKLPANGKNIISQPKIVENLHPSWQAKKSQNLGIVSFTGSKITFDDDDDIKADDESKTTAISNKRSFHQIEDNKSKIKKVVKKRGIVTEFKGKKIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYG3</accession>
    <name>A0AAD5TYG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000990">
        <property type="protein sequence ID" value="KAJ3208523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYG3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3208523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="112" mass="12658" checksum="DD3B86F5198B47AF" modified="2024-05-29" version="1">MNLSVEDSKLQIAAGLETFDRDDCLISEFLVEFEREEVRTLANSPINDGNSSPASPYTNSGRDVLQNNKKYQQNFQNKKVSVPANVTSQKTLNLLKKPDLQNWLNDKNSLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYN9</accession>
    <name>A0AAD5TYN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005761</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000464">
        <property type="protein sequence ID" value="KAJ3216713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYN9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000026">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="5">
        <location>
            <begin position="19"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="102" mass="11182" checksum="770DE1CDCA13E7F6" modified="2024-05-29" version="1">MASAEVQKIVKDLINSNKVVVFSKSYCPYCKATKQLLTSLKIQFALLELDQVSNGSSIQDYIEELTGQRTVPNTFINGKSIGGNDKLQALNSSGQLTKLLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ78</accession>
    <name>A0AAD5TZ78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl-coenzyme A thioesterase 9, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ACOT9</name>
        <name evidence="6" type="ORF">HK099_008056</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000848">
        <property type="protein sequence ID" value="KAJ3211219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ78"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03442">
        <property type="entry name" value="BFIT_BACH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655:SF0">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="5">
        <location>
            <begin position="72"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="HotDog ACOT-type" evidence="5">
        <location>
            <begin position="296"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3211219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="455" mass="52951" checksum="06477B1AEBC67D00" modified="2024-05-29" version="1">MRFQNSLRRFHTSVKLLSTDGAEISKNKLVQLKWSVVPQLRGRSEFTNRVWINRFIIKQKALKSGQPIIEGRYTEEYLAFKSDPGLLEEYINVYGHIRFGKILEDLDAMAGSVAYAHCDDLRDDTPPLTIVTASLDRIDLLRNIPTTDDIKICGFVSYVGRSSMEISIFMEIVPEGYAAVMEKKVSNEKQFPWIHRGKDRENVLLSAKFTMVARNPVDGKSVQVNQLSLETDEERRLFKLGAEQKSRKQVQTLTSFEKKPPTYEEMTLLHELYLEYRQYLDPSYHIPKPAEVVWMKDTIKQNLLICMPQHRNIHGNIFGGYLMRVAYELAFTTSTIFAKTRPNFTSLDDIVFKKPVPIGSFLSLTSQIVYTDMETNSFQVKVKADVINPTKDYQDQVDNTNIFWFRFKLDDDIALQRVIPRSYDESIRYLEGKRRSESYENNLRNTERFFNDHEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZZ8</accession>
    <name>A0AAD5TZZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000336">
        <property type="protein sequence ID" value="KAJ3219523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZZ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3219523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="498" mass="55101" checksum="2A6AEC8785D1227D" modified="2024-05-29" version="1">MSKSFSRAEVAKNNTEASAWIIIDSIVYDITRFAGMHPGDATEAFYDLHRHEVLEKFGPKLKLGQVEGESQKIIKMNFADYSPVPYAEHPSVVGFKSPYYTQKHLEYRTVCRNFVAKHVLPDALACEETGARPSKELVKLLGEEGYLAARLGPGKHLKGLKLPGGIKPEEFVTHLSFVSKLSVVRVMCRGYADGNSGGMVIGLPPVFNFGSKALKEKIVGPVLRGEKYIALAISEAFAGSDVAGLKTRAEKSPCGKFYIVNGTKKWITGGMYADYFSTAVRTDKGITMLLIERGEGVRTKQISTSYSKTAGTAYIIFENVKVPVENILGVENKGFQVVMSNFNHERWVMCVGSVRGTKSIIEECFKWANQRKVFGRPLINQPVIRQKLASMVALSEALQHWLDHTTFQMNNLSYFEQATKLAGSLALLKYQCTRVGHYVSDNAVQIFGGRGITRTGMGRVIEGFQRTNKFDAILGGSEEILADLGIKQAVKNFPNTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U094</accession>
    <name>A0AAD5U094_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ATP23</name>
        <name evidence="10" type="ORF">HK099_005478</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Has a dual role in the assembly of mitochondrial ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
            <topology evidence="1 8">Peripheral membrane protein</topology>
            <orientation evidence="1 8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase M76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000429">
        <property type="protein sequence ID" value="KAJ3217384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U094"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3217384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="221" mass="25433" checksum="841F87A61CBF0D3A" modified="2024-05-29" version="1">MSDSTKDGSKPPLMDKEKEEKKLLDNWTNSFKSLFSGATDEEIALKEHKRCEKWKKSLIKNNSLIEFMLENLKKSGCEFDVEKHFKCVPCDFKRSGGFSPELGIILCQNRFSSKRHLQDTLTHEMIHAFDQCTTKVNFNNCEQHACAEIRAINLSGECKFLTEVKRGNFGFASHHQKCVKRRALITLKDLDCCKGENVAEDALLHVWKSCFNDKAPFDEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0C0</accession>
    <name>A0AAD5U0C0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000893">
        <property type="protein sequence ID" value="KAJ3210394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0C0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="244" mass="27609" checksum="5CDC95390606896F" modified="2024-05-29" version="1" fragment="single">MEFNISEEELYQSVWEDQSSPKQKKEAEESGDDFLFQQKQKQQTLSFQDQLQQNPVYFNEEINNSHKFGSVDPLFNFQKPAAKQHVPFSMHTETKIILPNFNDPLLTMENTGLEETTPLDFGTNPLSGSFGGFNEQSINLKNSSSSQDITAELEKLNIKSKNHFRGDSIDSNLSTKLNSYYHDGNDTFNPNILPSATSPKSAKEENSKKTVDLGPLGDDFGEPEKVVTEKKRKSLVKFEKSLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0G6</accession>
    <name>A0AAD5U0G6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000336">
        <property type="protein sequence ID" value="KAJ3219517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0G6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="847"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="856"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="877"/>
            <end position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="969" mass="112148" checksum="256C0CC8183978BD" modified="2024-05-29" version="1">MNSELKISLLNEDLKLSFNSIRVENDESDELNVDNMKKKLLSVLKQADLLTDLSQSKLSKKVLLSTYLSELSGMIESSTLVDKKKAVHFKIELESKVNSFLKSYFGLPDCSRINFQSSNSKNFESEKLIKVCRAAFFKLLNAFLHHPTMLVPTFYIPDDENCYRICSTILKEWDNITYGVEIAGEPVLRIVPTLRNSEKLNCEKLEEFITADVKLDRKPCLVIGRAGTPITGELDDIQVLLELKKKYVFWLHEEGELLSLLINNQSSEIVSEKIELIRNFDSLSADFGKWFDFGNDLPIVTFFNSIDWSCHQNLIEEEDQFENRLLSSIKPFITNKTAVLKFKVFENGFVKEYKKLPKSEYVPYQFHEEDDFIDVRYKLYLFLTYIYLSDSQNLHLTLPLWTFCEHSGLEMLIDRVSNARKLVKTSTNIISLSENFSLLEEDDANCLKLLFRFKTKNFPINHFPEEKVVVKDLNSLVDSIGQNQKNLLFEEELEISNDGTKAVFANLPEKFRKKLRLDLIEIEGVQFLRYSPLRLEIVYEEHEKYLCKALEILIKEGKKIQSSLNLKKKFKNLIETKFKQLKFIEKLKIKPILNFPTEKNQDARGCSNDGEEKIKIKKISGHEIFFGLGGVRYFPSFLGSVGSDFNEESLNVGILKEIQDLNIKISKSLIERGKTIGWEKLFALGKFVDSDIDDDLNWGDNNSSIFKMNENEVDELKYCIRIGIDKEPFDENRLIDILNLINETGLNLEKENRVVDHVSEMIKRGIKLAEQELRNENETQSLNKKIEELQPFENSRPLSSYNSYGSLPYSPVENSSQSNWKFESEQRHRKSYQNNLKIKTVQEDYGGKQRYERSLSRNSFTKSATSNDNKFASNANKYEHVSSTSREDAYNNHQINRNERKNSFTFKDSDSSHYAPEKNVANNMKRLSRGESIISNGNGDNLRNIFAQNDLQGLSETTRKVQILIKKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0S1</accession>
    <name>A0AAD5U0S1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RHB1</name>
        <name evidence="13" type="ORF">HK099_006082</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endomembrane system</location>
            <topology evidence="11">Lipid-anchor</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the small GTPase superfamily. Rheb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000501">
        <property type="protein sequence ID" value="KAJ3216054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0S1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04137">
        <property type="entry name" value="RheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000273">
        <property type="entry name" value="GTP-binding protein Rheb homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3216054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="21131" checksum="57F022BE9D5D4B9E" modified="2024-05-29" version="1">MSSAPKVRKICILGSRAVGKSSLTVQFVESTFADSYYPTIENTYTKIIKYKGQEYAAEIVDTAGQDEYSIFNSKHAIGIHGYILAYSISSKQSFEMIKVVREKILNYAGMDWVPIVIVGNKSDLHNSRQVTVKELESLATEWKCSYIETSAKLNQNIIKVFELMINEIEKANGGLDGGGSGANKGKECLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U194</accession>
    <name>A0AAD5U194_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">triacylglycerol lipase</fullName>
            <ecNumber evidence="6">3.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Autophagy-related protein 15</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ATG15_2</name>
        <name evidence="20" type="ORF">HK099_005293</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12044"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17855"/>
            <dbReference type="ChEBI" id="CHEBI:18035"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to both phosphatidylinositol (PI) and phosphatidylinositol 3,5-bisphosphate (PIP2).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
            <location evidence="3">Multivesicular body membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Prevacuolar compartment membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000403">
        <property type="protein sequence ID" value="KAJ3217934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U194"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005775">
        <property type="term" value="C:vacuolar lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034496">
        <property type="term" value="P:multivesicular body membrane disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046461">
        <property type="term" value="P:neutral lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006660">
        <property type="term" value="P:phosphatidylserine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050805">
        <property type="entry name" value="ATG15_Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47175:SF2">
        <property type="entry name" value="LIPASE ATG15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="19">
        <location>
            <begin position="260"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3217934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="416" mass="48060" checksum="7FB55DB08864240D" modified="2024-05-29" version="1">MKQTFLLSFLYSFSICFNSNLKVKHLLAFSKFDVIDEPILVKKTLDDFEVSSTSDRNLYEVKAVKKTVVNPFKNLNLNYYSKNTFKLENTVNDDFFTANDADDDYFFKTTGVDAHKSIYAPDMTDNSTVYSLALMSSDSYRDFEWIEVGGKWNVSGGFGWQENAIQGYVFEDPDTNLVVVAFKGTSLTGRTAPLDKYNDNMMFSCCCARVDVTWRSLCGCADKKSEFTFVDYLFNKKKHQCDWECLRESSDFDNSYFKLSERIFKQVEKMYPNSHFWFTGHSLGGAISSLVAASNFYPAVTFEAPAVRMFAERVGLIPSKHFPMYPVSKRVWKQMLDDYMAMLPIYHVGNTGDPIYTGSTFEDDNPNTLDHVQRRTIRHHQINYLIEHHLQKTNVPECKVQENLECEEECASWQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1F7</accession>
    <name>A0AAD5U1F7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-3-methyladenine glycosylase I</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000239">
        <property type="protein sequence ID" value="KAJ3221283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1F7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052891">
        <property type="entry name" value="DNA-3mA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30037">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30037:SF4">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="22908" checksum="B2C65AE77169679E" modified="2024-05-29" version="1">MIEKVRCSWVGSYPKKDTLLTEAMIKYHDKEWGFLNNTTNEYLFEFLILEGAQAGLSWSTILKKREGYRKAYMDYDIKKISNFTEKDKANLISNAEIVRNKAKITASIVNAKLYLKILDEYQNSFLNYLNSFEYTNVARIQGQTSLTESEISKKISSDLSKRGFKFVGSKIIHAYLQAIGIIDDHDYDCFLHQRNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1I9</accession>
    <name>A0AAD5U1I9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin carboxyl-terminal hydrolase 14</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Deubiquitinating enzyme 14</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquitin thioesterase 14</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Ubiquitin-specific-processing protease 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_003820</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000256">
        <property type="protein sequence ID" value="KAJ3221042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1I9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14385">
        <property type="entry name" value="UBA1_spUBP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14386">
        <property type="entry name" value="UBA2_UBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000086">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000103">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46713">
        <property type="entry name" value="F13M7.16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46713:SF1">
        <property type="entry name" value="F13M7.16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="USP" evidence="17">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="104"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3221042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="235" mass="26449" checksum="C108967D5B859A3A" modified="2024-05-29" version="1">MLNKVLDSPLEVPFTLNLDAYRAKGIQENEEILPEDTASSEPAFNEELLNQLLQMGFPEIRCKKGLLATGNTSADSAMNWLFEHMDDADIDHPIIPNNNAGSQNFDENDVNSLVEMGFSNAQAKKALKETGNNVERAVTWLFSHTGDPMLEDDQLSSKTSNSVEIDSKPANYQLFSFISHKGTSTSCGHYVSHTLKVIDGKKVWVLFNDEKVVLVPEKEIQKSLREGYLYFYRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1S0</accession>
    <name>A0AAD5U1S0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase-like protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">METTL4</name>
        <name evidence="2" type="ORF">HK099_003358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MT-A70-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000220">
        <property type="protein sequence ID" value="KAJ3221598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1S0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829:SF4">
        <property type="entry name" value="N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="382" mass="44633" checksum="2BEC10387697F5E4" modified="2024-05-29" version="1">MDSLPNSLEPEIVVIFQEVQIGNKKFKSNLIHTPFSTPNIENKKRNKKVKQNPTLYKKYEALKSLFTEDQVMVSKLYDIFQSTNLDFGLNFESSMKEEQNSFNSAIVPSFDFLEFGKLSDKTLHFLNSDEEFKVKTLQDLGAQGNIDFSLLFNHIIKNTSDEPQIISIFEDKFIIPKRANFLLSDISKLEPLINFSKYDFIILDPPWKNKSVRRSKQYNVMDCYDLFKIPMKELALGVVAIWVTNNPKFCKFVKNKLFPDWHLELIGEWFWLKVTTAGEWVFNLQETDNRKPYERIIIGKVKDYASEKISYKAIPYHLGIVSVPGKHSRKPNLSDIFNKYFSSDDDVNKLEMFARNLTEGYTSWGNECLKFNNLSYYTDVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1X1</accession>
    <name>A0AAD5U1X1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_003179</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000212">
        <property type="protein sequence ID" value="KAJ3221727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1X1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006413">
        <property type="term" value="P:translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23793">
        <property type="entry name" value="UBCc_UBE2E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000101">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="entry name" value="Translation initiation factor 3 (IF-3), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="Translation initiation factor IF3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="264"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="403" mass="46561" checksum="F32585FFEC69F27A" modified="2024-05-29" version="1">MNIVQLAFRPSSLKFSRSYSLNPLKSKSNTKFTEKFKKNEEIQLNVVNVINEKGEKLGMQPVEEVLQNLNLETHDLFLVNEEKFIAKIVKKPLITQVENTQKKVELKLKEKDKLLLQKHHNTIKELEINSNISKNDLEVKLNKAIKFLIKEYPIKITIKDISAKHKKRLERVTETSTWNFNETSKFDHLEFIQNKLKDFGILNENDFIKEKNFVMFTMRPNMDENSIRKMSSETTATTGISTKPTSKWNKPVMSSSAKRFNFKEKEILIQKELAEISLDPPCNVNAGPKGDNLYEWVSTIMGPQDSPYDITFPSDYPFKPPKVVYRTRIYHCNISNTGAICLDVLKDNWSPALTISKVLLSICSLLTDANPNDPLVASIAQQYISDREEHDRIARDWTKRFAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2A8</accession>
    <name>A0AAD5U2A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonucleases P/MRP subunit Pop8-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000440">
        <property type="protein sequence ID" value="KAJ3217176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2A8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042859">
        <property type="entry name" value="NOL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049128">
        <property type="entry name" value="Pop8-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15633">
        <property type="entry name" value="NUCLEOLAR PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15633:SF2">
        <property type="entry name" value="NUCLEOLAR PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20976">
        <property type="entry name" value="Pop8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonucleases P/MRP subunit Pop8-like" evidence="1">
        <location>
            <begin position="21"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="790" mass="88924" checksum="916C102BBF7CCCBF" modified="2024-05-29" version="1">MKNCTISKHDWYYALISLNIPVEELQLRSIINSLMFEALGLAGQSISCDILKTNNNDAIIRVPYDGSVTTKTPFTVRFSVFDNCLLLSVNEAAIYQFNIDHSNSPSNSWSLPQKFILNTPATTFFKFSTGGTMEDEETDLPSRFYNPVYAVLNSKVDLNKNDQNKVIAQWNTDLSKGSTTVKTQASHFKQFSKAIANILPTSCNHLILINTDGSVTVTASDLSLSEKLVEFTPESEGFGGKLLYSKILESINSNNVKNSESFTRILTVSESLTDSKVLLRFISVSIKSKISSIKIEETANTYLDVDIKKKNYIFCINDKLRNFLVGDSQEVKVYQVRWNGTFGKTITSDLIIPLPFYNQQPSICFMALSYIAVLGHQKTDNGWEDVLTVFDSTYGTIQSQKVVSAGPSSKSTKKSYHMEITNSPSQGSLLLCTITDSSENGLISSFKTSCNMIPYHATELSLLVALGKGQKSLNFEDKLILQLSDSLSTTTTVKYEELFLKFLQSRYVENSDKQYDDICTFPTVEIKHNEIQAISSRIFGHLSKQFYPNSVIIYLLNTGMMSTKFDGGSIVAELVKSNDVKLSTMAIGKCPDVTENDIILTLELVVKQKEIGFLKRSNLIASLLSKNRNDHLMIQEMAKLDINFVLEMLNWIEDTVGDDLPMEVWWLPKGKKNRIELAVDLFSILIDAQYAFLIMETNIHSRILSLRHIILNYKECCFLMETKLRGALSSVHFELKDNAENKLKPKDYNYSNKGSKKSTDFKEKGKKWERMVGDVTDGVGHYAVEVFKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2P9</accession>
    <name>A0AAD5U2P9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000525">
        <property type="protein sequence ID" value="KAJ3215716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2P9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="88" mass="9889" checksum="FE1353F68E4072F5" modified="2024-05-29" version="1">MLFQSVDQNEWNEAKNSYKKAIETIANKKKTAEGTFRPALLKNVESNSEDLIASSFTESLKLLTEGNCLGALKTFSKNLKVIFNLLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2R0</accession>
    <name>A0AAD5U2R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000397">
        <property type="protein sequence ID" value="KAJ3218071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2R0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="310" mass="35042" checksum="05976B0F76856DE9" modified="2024-05-29" version="1">MVEIIGRILNERGKRERDRVSSVLCGFFVFFAIIYANYRSKVYYTQLPATFTTTVEPRLLFKSPFFSKFFTTIPSKDFEFPAITVCPLDNFASIKFETCNYCHDSGIGITQKPILVLILFVAVYHTENLGMFGKGLQCISLNEEPAPQIKVSNSSDSLDFTLSVHGGKEGGSAGVIVLVHPRQMTDSGMYLSTVSPTNTFSVNLNTVNLITILKEWKVKFNGSAEQDYQAKGNSLNIYKLNNTALNSNNIVKFSAKFSDFTVLYEKEFNTLNVIHRFVMFFTLLLLNKKNSYSENLLAKANRDEGFDRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3F2</accession>
    <name>A0AAD5U3F2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000223">
        <property type="protein sequence ID" value="KAJ3221557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3F2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="156" mass="17734" checksum="564141E395D3BD72" modified="2024-05-29" version="1">MSTALERAKLRVQKLKDDRIHTHSTYALNDDAIVKNQVNDIIQLQSRIHLNNTKSNNALNSQLFDKLIENKTLDLNNSLGASQHKKYARKLPSQRTSVITQESSSSLPESNTTEVNNLDEKNGNEVEDTQITSVEVKIFFGFILVKNLKNIFNSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U499</accession>
    <name>A0AAD5U499_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NFACT RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000117">
        <property type="protein sequence ID" value="KAJ3223789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U499"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039730">
        <property type="entry name" value="Jlp2/Ccd25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049">
        <property type="entry name" value="DUF814-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="162" mass="19254" checksum="9F91B26875C1F5F1" modified="2024-05-29" version="1">MGKDKYENEDLIKHGFEEDVWFHVDKLSSAHVYLRMKKGQTWDNLPEALINDLAQLTKANSIEGNKKDNVKKVLVPARENAIINRLNKTKNEEYPDLQMQKVNHLKKKRAEERSVEKSKNEKFNRDYEEQKRLEDLITYKNVLLENEMKSNKECPIDEEDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4G6</accession>
    <name>A0AAD5U4G6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000252">
        <property type="protein sequence ID" value="KAJ3221089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4G6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="540" mass="60850" checksum="2F3B242466FA3621" modified="2024-05-29" version="1" fragment="single">MENEVVISEIVSESNQAHSNQKTETCIQIHSSQPIKSSSINTTVDKNSKIVAIIPHNNLSMFEQHFIKQNILMVFSLTITTPKGLSSFSKRNISDIIKKTAASHYRLSATVKEDLFTELPYHTADELNNLNIQFCNSNDVKDTFIGSLNYNFAEHLENKYLWRALVLLNEDDLQQWNIDSQITFTVCWTIHHCLGDGLSMFALARTFVNNCTYDNLEGNTNLSRVEIDKSPPPLMDNLFNPWFIETIPALYEMLWSFVKRKVFTVMRGRDVGSLKNFTPSTTNLLESSAGTELTRTSTNPASIHNNGENKTNAKFLWFQKDFITKLRTKCKVERTSIAAVLVVAALCASKTCGEKMEKYKLKGVPNRQGWVVTNSLRHLIPGSKLIEGADKETDPATAIFGSYAGSISDPALNLKDTKNFWLTCQKVKRDINKIHFSSIARLKLSNYIYRKPSLFKFMQSKVDLKAFTRLHSVEIANLGAWSTPESDIIINDIKGLVNCNFDGSRALFTLGVITVGGEMSISIGYCEEAIYEEDAILFTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5S3</accession>
    <name>A0AAD5U5S3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FMP27 WPPW motif-containing RBG unit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000062">
        <property type="protein sequence ID" value="KAJ3225411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5S3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019449">
        <property type="entry name" value="FMP27_WPPW_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01216">
        <property type="entry name" value="Fmp27_WPPW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042090354" description="FMP27 WPPW motif-containing RBG unit domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27 WPPW motif-containing RBG unit" evidence="3">
        <location>
            <begin position="38"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1162"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1184"/>
            <end position="1194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1216" mass="138637" checksum="5AD46B73EEE3DA38" modified="2024-05-29" version="1">MENRLLRSIGSFHLKVTMLPLVLGLINEMEGEIQSGVGLRCRAEKMDIDMFFVQKLIKNSLQEVNLDSSLSSQPRIKHTATSWSLKESEIGFTELEGRTISFGNAYNMLLGGIANEAAVYGTAENSAVDDKDHDEDWAEWILDEDFQYMEDTSKLRMIPFIWSPKISYFKRTEKEDSSMIEDKVRSQGYLYGVQISLFKMRLKEIEASIRHYMEIQQGLEYRIGILFDDTLRQQSSIIVEKLAFLYEKKAAIRRYIKSCSVDKNAEKEPPMVTLQRSTPSKSSPNISCFPEANGKALFDHYYIIHNINLLWKKEVRNTLFKLFDLQSKSLAVKYFMTNDSNRLVKELISTVSQKGVGQEGNLYDGEYAKNEFSPQKLATNSKVGFFDQDMAVKLLQQLIKDRDSNFGEIEVQNETNSGTETINFGTTLKRKSENFLASQFTYFSSKDPDSPDYIPPGYYADSNNIILLVNPQINFEAEFGEHKQLQTMVVAAENMELLSISIVDSSYKSDYVEDSTEMVAKTRKILNIHNAQFFVARSVDIEEAEDSDLDNIIMRSTLDLTFEASKSEITWPVWVPIECLVDHNSHIGFLQRVMERTSATAHRDTPNTLYVKRSRSNCDTKSNFVHADVFHINFPTFIISVTSMQYEIVYNIITNLLVYRDPMRGQRNDRRRKMILGLEQMSDLQKVMGTVINLQDKIRHAETLLKYRLGHKKHVSKVSEVRQVLITYMDELYVLMEALKEMLSLSRKKESVDVAWMLNVTAGKLIWIMKLDSGDPLCQWNFDVCTFNYIQNEDQSSSNTLEIDKLYIENKLDPPSGFKDLLSPFLADKRALDFNKHKLLRIYWSELAPVAGIPVVEHFEVVIFPISLNVTLDIGRELVYYVFPEKKAKALAESHELPFPASEKSYPSTYAPSLTASVQPSQNFYGNNELKNYEGALKPPKKKKAALSELEILQSRASENKSFIYIKMPEFQLCLSYKGSKEKNVEDLNRFVFKMPTLEYRNRTWSWLDFYDEVKKDGIRAIFDNTGSLIKEKLFTKKTAVAENLSNSTPFLTPLPSSLTTSIVGIIPSPIMKTSKSMDLPRSYSDLSAISVHSDNKSVYSAISAGDNKSVSNNSYQHSDTLVSPSASTNLEKRKGKFSFFKRKDKANSTEMLLAEDATVEADSSQSNSKTSMGRSGSFFLSKGGSTSALSENGSVKEESPRNTFFNLRRKSEKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6I0</accession>
    <name>A0AAD5U6I0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS25</name>
        <name evidence="5" type="ORF">HK099_001869</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000158">
        <property type="protein sequence ID" value="KAJ3222801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6I0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004977">
        <property type="entry name" value="Ribosomal_eS25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12850">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03297">
        <property type="entry name" value="Ribosomal_S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="138" mass="15337" checksum="D454F1A6239EAEAB" modified="2024-05-29" version="1">MINPLVVHGWDAKAQQAKVAKPSGKNKKKKWSKGKVKDKANNAVVFDKATYDRMLKEVPTYKLVTPSVLVDRLRVNGSLARLAIKDLEAKGLIRLVSAHGSQLIYTRATKVNDIVAEPVEKVSKGKKSKKVEEDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6I1</accession>
    <name>A0AAD5U6I1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000209">
        <property type="protein sequence ID" value="KAJ3221784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6I1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="388" mass="43701" checksum="68FFA3221C845165" modified="2024-05-29" version="1">MDLDDKSTLHRNPHFQSPLPNSLANDRLASDSSLNYKNYKNKSWKRFFVVENVYSRIALAWTILQLVLISILELVILVVNKQNYNKLTSVATLNSTRDLDLLGLEKNASALTVYHSLFIVAQFFQLLLAFDGIYNRSIIQIVSTTCFNLICCAYSVVQSFQAFDIFHKAKGLILGSNHPTFTLEIIVIVLMVIFSIGWIFLSFKLYRVFGWEIFKDLGADKTVKDQLFVYHIFLMLLKLDVFFFIGFTVQYLILVISYAQSNTTIDMWVHGCIAMPSALILLIIAYLAVHKESNILMAALLLGLSTGIGYLISKIIDVTTSPSDSRKYVGAKNSLASFEIITTLLAVATFIVAIMCYKNFGKGLMELFNKKKGNSKEGGRSLLTPELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6T9</accession>
    <name>A0AAD5U6T9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004983</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000037">
        <property type="protein sequence ID" value="KAJ3226405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6T9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053027">
        <property type="entry name" value="AGGF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106:SF24">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="102"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="165" mass="19132" checksum="9CE1B5CF902749CD" modified="2024-05-29" version="1">METDLKDDGSTTNSTSKNIIINNLTTKNNSSKDWNDTVDFYQEEGEILESEGEEVEISKKNFVEKNEEINIKKDEDVNLKLFVKKSSLLKRNSVILVKSEGISIGRDRNFDKFRLRLKELQVSKFHSTIFRVLNKQNLKFEYQITDLGSLHGTFLNLKRLSEPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U702</accession>
    <name>A0AAD5U702_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pleckstrin homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003974</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U702"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF2">
        <property type="entry name" value="MIGRATION PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pleckstrin homology" evidence="3">
        <location>
            <begin position="745"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="624"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="636"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="954" mass="110154" checksum="6FC1E80EC898E652" modified="2024-05-29" version="1">MPKKVISVMRSSSFDNKTTLAKEIFKQKRDLTNYELIEKLKETEEERNLAATLGQQLLDQNKILNQKIKSLENEKNHKIDSQLRLEIESALTKQVRTLQSKFEKCEQSRLELFEKFCDMENEVHILKREKEKRNGNEEKLDERCWELEIINQQKGEQIAEFHSELNKLKIEQRKFSQENNNLQLQIENFKQNELQLKLKSEEDQKIIHSLKKEKKSLNESLIKLSKELSETKLSRNEVPSSRNCTPEPILVTDDKSSPSPSISTTEGKNTFNTKSPTRRNDLQQTPPKPTKNEKVTTPTLDEKASLIKSINSIYQSPSPNRNKNKNEQDAFRKSAILKKEEKKQNELNKKLDALCQRLHQADYEIENLKFISEQFQNENFELKKIVLDSQETIELLNFKKNEDELSKVNIALKQEKSELFLNTFSKEVSLSTSLNSFKEFTSVVNQSSQTEEIEKTEFDSTLNLPFEKVRDSVQSAHLKEKLKETLINKIEFPENSLTLNETLFDTNNNTAENYKNTGTKSSSENQYLLTSNNNQIVPSVLDNLSKSENSLMEYLQNSQKVISNTENFIRRTRTASQDVLVNKRMVAPKRTTLCRPLITVSPQRQIIKKTFVINKGSSLSKIVTENEETKEAPDQSNSESISSKSSSNKCSISSPTVRMNKPFRSFSTSTNLSLSKKPESNFKLSTNSTPRKSKFFLKSKTLNTEDDISSVISGDDISIVDDDFSEVEEVFINNSNDEVEARNPVEALTHTMIGSWFQKFNRRGKNAHHRFFWINPYLRTLNWSVKPPSQEKKPKKHKTAFIDSVTWQELPEANVRKTYPPGAENCITLVTNNRKIVIIPLNWFDHELWTMGLTLLMKKSGNYLDNPLEQDFGKESKKENKKSINNTSHGSNNGGVGIGLNFLEEVKRRRLMKEKKEYDEKLNEIALNAESVDKFEQIEFFKRLGSGEMKVDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U757</accession>
    <name>A0AAD5U757_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">NEO1</name>
        <name evidence="22" type="ORF">HK099_006871</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 19">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="JADGJW010000062">
        <property type="protein sequence ID" value="KAJ3225413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000085">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000009">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001846">
        <property type="entry name" value="VWF_type-D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00094">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51233">
        <property type="entry name" value="VWFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="VWFD" evidence="21">
        <location>
            <begin position="981"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1199"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1199"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1321"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1339"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1353"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="521"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="545"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="574"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="655"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="656"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="657"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="737"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="743"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="763"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="766"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="767"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="767"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3225413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1591" mass="176603" checksum="A2F81C00319AA28E" modified="2024-05-29" version="1">MEIFKASKSRTTTTSDGSFEDSIPLIDLTQQQRQTFEHKFKKENSFLSKMNVFKKKKKVPRTIQLNSEKDYTTFSSNTVKNQKYTALNFLPKVFFEQFKYFFNLYFLLVSLSQFINSLKIGYIFTYFGPLIFVLMVTITKEFLDDYQRMKRDEEANSQIYKKLTKGGVKEIPSSKIQVGNLIFIGKDQRVPADCILLRTTEESGASFIRTDQLDGETDWKLRLALSATQELNSDEELLNLKGSIYAEAPHKDIHTFVGNHTRVHSNGKTIDPLGVENTLWTNTVIASGSVIGFVIYTGQDTRAVMNTNFPSTKVGILDLEVNNLSKTGSEVAFRIFPFFNNRFLSLRVNLDMGKSVYSRQIMKDKKIPNTIVRSSTIPEELGRIEYLLSDKTGTLTKNDMELKRIHLGTMAYGADSMDEISSHLSTAFHAGQDGAFRYKRSRDISMRIKDIVQALAICHNVTPVTESNVLEYQASSPDEMAIVKWTESVGLALVQRDINKLELLGPDGINYKFQILDVFPFTSETKRMGIIVRDLQTKEIFFYQKGADTVMTKIVAYNDWLDEECGNMAREGLRTLVIARKRISEDFYKDFQKHYSEAKISVTQRNMVCQSVIGKYLENGLELLGLTGVEDKLQDDVKNTLELMRNAGIKIWMLTGDKVETATCIAISSKLVTRNQAIFQISKMSDPLDLMDELEKVKHKKDCCLIIDGESLETSLRHHEEEFLNIAVRLPVVVCCRCSPTQKAEVTSLIKNFTGKRTCAIGDGGNDVSMIQEAHVGVGIVGKEGKQASLAADFSITQFSHLTRLLFWHGRNSYTRSAKLIYTMAPVFSLVLDKDVSEDTAIMYPELYKELTKGRALSFKTFFTWLMISVYQAPALTDLLEFDPPLLTLGTNGSGKFKCRPKLPPSKPVHKYIFNAPGFSFSNCDLEFNDLDYQTYKEVEIFALPNFSKKTAEQKISIGYAESCSTDNYEYKASYNYRPGGTCLSTGDPHYSTFTGQAYSYQGSGSYYMVKDANLQIQTRLFSCGKGKNLHKVTCNDGIAISYGSSAVTLQVAKTHLTSSKLSDAVNENEILVSQTGKDKTSYDVKLGDGSKITVKSNTYTKDKSYLDITIKLSGGSYENVGGLCNYLPGGKQVHYVLPNGSVTKKSEEFANAWKAPANEDMFSGNWKPIAPYQDKPQKTCNIKPTLCTTSQASTSTTTTTSYVSSESTTVTSSSTVSETTSYVSTQTTPYISTTTTTTAESTSTSYSSSATTSSYSSESTTSSVVNESSSIFSSSTTASEYTSTSSVVNESTSKSSSTEPYTSSVPETTSEPYTSSVPEATSQPYTTSVDATTTNPYTSSVVATTSSKAPEYSSSQVLSSTETKPYVTETTPQTASYPTTYTKITSCPVITEYPAYTYKPVPTESTEDYSEEEEEYVPADYNIAKEQCEKIIKVDALSSMYDPSFYINACALDYSQSGVFNFVENARQSYLTNCRLDLEYLEQDPEPAQRKVAKELKASYGLGLENECTNKCSGRGTCTPNGCACDAGYSGAGCAIDVSYVAANSSIYNEDGTQYKPQFQKFTESAPPANSASKISVLGLTFVVGFLALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7A3</accession>
    <name>A0AAD5U7A3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4200 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000128">
        <property type="protein sequence ID" value="KAJ3223482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7A3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051147">
        <property type="entry name" value="CFAP_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025252">
        <property type="entry name" value="DUF4200"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13863">
        <property type="entry name" value="DUF4200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4200" evidence="3">
        <location>
            <begin position="57"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="57"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="176"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="269" mass="32125" checksum="5CAAA8CED4E9286F" modified="2024-05-29" version="1">MIAVEQLSKINQNNNDTFVTQRGGKIINDGTRKLGTMLFKTNEALFENNRTLQSTLLLQKKKEMHQVQQLLEKKRIEFAKRMEECREKQEELKVKQKQIRERVFKFEKFLKENDAKRQRANVKAQTEKKLREQKEQELLGLQKQLMEESKNSKNILTMLPHINDILMRHKTLVETNEDLMSMLQSFQDEIEKEQKGLQLSIKNKNDEILVYNSTLGFQQKKLDKMKQNCANLEQKQEEKDRTGKERVKNKEFFCFIIPRCEYLEKQNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7N4</accession>
    <name>A0AAD5U7N4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nuclear factor NF-kappa-B p105 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NFKB1</name>
        <name evidence="5" type="ORF">HK099_001775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000154">
        <property type="protein sequence ID" value="KAJ3222890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="322"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="411"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="624"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="878"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1144"/>
            <end position="1171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1319" mass="149394" checksum="5244504D21630B0F" modified="2024-05-29" version="1">MNLCTFSFSNDVKHVEELLGSGLNVNETYTWAIPDASVDRSERSYNALPLNLAVIQGHVAMVNLLLNNGAKVEVRDGKGRTPLICALYGSQDTMKIGPENYTTITNSSLQHIEIVRSLLSATRSEVFSDVVDSPQNGEKLRGITPLCLAAYLGKLPLVKLILDFGADVNGLDKNARDGHIEVVKVLLDFGARHDIKDVNGWLAVQYAQTYPQVVQILQSEKCKSSLVSQLFNKDLSNELLRKFPKFHRALGSCINSYAVDLKLEHEVPLIGKVLNSTNLKLDNLKQTRISIFVFIKNYDFLGLLKLLNTTSEFDLNYTDISSGLTPLQYAARIRPLKKESEKIIKLLVSKNINLNIQNSRSGKTALHYLIKDPELLAENAKGEQKVIADMIASSLNCLLLANANPNIPDFDGNSPLHLACKSGHKDLIQSLLKYGGKINVVNLNGDSPYSYCSNQNSRDILKKYMQSKDGNNVAGSIKNDSAFNSTECIPQQRMMMGSVDRDLQLYQLNSLPIFNIIDEIFLQFDTPSVDETEMFFPEENLGSLSSAKQYDEILEEKMKLNLELISQYQKEIDLMDHLEENAAALDTSLMIIDRLTVKYDVNTKKWEKKGFELDRKIKVLHLALESNEKSYKSLEEVLSNLQFELQCSEKLNSLKESRIRELESLLSSKNEILRNLTKKFDEMSMCKDLDEDSISQQYFTPRESMEISSHEKNYELNMAVLRSSESELRESLHETKNVRKNLSTWRQSIQAGKFLNSSSKIKSNSLMLEKLLEKENGLLKEEERLSHEKSNIMMRMEDLCKENQDYLNNEDISEETLSVEELLEKLYRNSSLTNTSLNSEKGIKANFTRKSRVAYDATQNELDPVMLNRLLIASKSRINHLKTTLSFLRSSNDSLQEQLDETNKHLEDAYSLLRTEAKKNTVIFDVSKSNPQLGDVCQEKNQSLLTNEKVNSSKSADLDQINHIMDLLVGLSEGVEGKVLAKLDLILFALGENSEWNQNNCYEVTKNFKKNSGAVLEKNYDFTEYIKHIKVVLEICSKKLNAVQLLIQSVEKKYDIPDSNENIKKTIDGSIIVRDVITVENGNASVECNVTTNENNFLNIAPSDTPVSCSSDRIIEKFNTFGFKSSKRVDELEGEVEVLVQDDIPTLLNELQETRQQISELEAELRSRRLSNVEDSNLNNALMKKRKHYKTLVRSLTENLKAHNFASPPRKSTSFSETKCISLVETDTFEKRFAITPLENFEGRIAETNQKQMEKMNPESVNSGNLLLPLELKNLEITERPCRHGNDEEECKENNDVGAALIAKLKKVGTSLKYKKYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U842</accession>
    <name>A0AAD5U842_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005227</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U842"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015007">
        <property type="entry name" value="NUP2/50/61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08911">
        <property type="entry name" value="NUP50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RanBD1" evidence="9">
        <location>
            <begin position="576"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="73"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="453"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3228217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="694" mass="75692" checksum="A8D8D76895138083" modified="2024-05-29" version="1">MSKREASDNLTKDNYMVEEESQVNDGIQRASEEVMSTRQIARPRKSKASALRKNPFQSINMLGKVSNKSTPLFSFGPSAPNTSLSTQSITGSSAQTDDKNGPLPAFGSTAGNFSLLSNTSSKNSEKKSENAPLFSFGTPLPATSQAPLKTSTNMFGTSENDKKSTLFSFGTPLPNKSPISKTSVTEKSNNKVTSFSLEVQSPTNNMANGSGTKNNNLNDKEYNWGHDLAKNLLGLNQSFLETLQENFKKNSLQNFKNFFDDYNLQRTKLLDKYEIAISKIKSGIGKDLGQDIIKDSEKSSTSHERNPTNNLNISFSQSQHNMGSIFNTPMKQPEPVTGNYDKAISGASSFSEIQPTFSFNTKSTAKTMDHPANTVLNTNEKIHNIGAPVLIENSNETLDKTSTPKVTNKFEPEKLTFSFNAPSTDTAIKDSGLKLDSDIPVPSNFMKFSSPFQTEPTSKFTNPTFSTGTNPTATSAPTPSPLSFSFSAGPPAPKQSEIVTPAPLSFNASSLNSFTPTFQFGAASAIPSATSSIGPLFGSSLSNDSTTNGGGNDADEGATEEALEQIDTETLMEGEGEEDEETVYTDIVKVSEIVKDAENFKWKDIGKGELRIKRKKNESNKCRILVRSPEALGRVLLNCLMYDGMKLKKENEKKVTLNCYIYKEETKQNALVKVCITFKSGADPFIKEFESLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U898</accession>
    <name>A0AAD5U898_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007773</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000079">
        <property type="protein sequence ID" value="KAJ3224836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U898"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="747" mass="87398" checksum="EECDBC7FE7B5D49B" modified="2024-05-29" version="1">MEVNKLNSLFKDWLIGCKGNELPMLIGISWKKKNSILEKAVENLPIKLLNTSSVYKLKKDGAILYKILSSICYKFDVDPSTYKESLTAILNKNEKKEIKYEQPSKSERVNINNFSPWLITAKTNFNIHKTTLASSSKLNLTTKFKSDYDISFENINLKNQIKIEVTEKLLYREISLNVLNLFYTIVNNSKYKNDNDKLVILIVDIVTLLKSCLKKNENKDTIHSSNFEFQIFEEMLTINHKEIQTNTKIIKFLLSTVPNVENNNYEINTSFEEGKILEEAKENIFLNNLVQKYFSKAKLKSIKEDEPVLGAVLILNQAEDPQNDALNESKHVRELKKKKKKGGVIEFITKNQEEVLSNHKNSKGVGKHENCIKSEFDFIIENFLIDLNELNNSIILKKVLVFSNFDNFGEKVLSSAVGKVFVEKFLHYLLEFPFYSILKMPKEELLDGKKDNFNNIITVKTLYFKAIKFLSKFVEYWITENTNWSNWNKLLNHCIKIVEMGSTDEKILAGHLIHKIFKKYVSLNRFSSFRLQWIETTVKILLKEAIQLEKFQSMFFEKIIDIYAVCSNIIEVMLLLIEVKNDVINQLEVDFFFNFTSSLMNVLNLFKFLNFKFTKDNKNKPDLLLKKDFGNLELIMKNFIFIVGMYIKSTYIKLTVKFNQENKLYSEFRNFYFVLQEISYFTKSNATNITSNDNFINFVQKWINLLSFMNYKDSVAFVENSVNGKDIQELWGKSLFKKSCCLEHENW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8N3</accession>
    <name>A0AAD5U8N3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FUR1</name>
        <name evidence="11" type="ORF">HK099_007142</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000067">
        <property type="protein sequence ID" value="KAJ3225224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8N3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000023">
        <property type="entry name" value="Probable uracil phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="10">
        <location>
            <begin position="17"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3225224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="211" mass="23329" checksum="4B6E3AFEEA3D8B53" modified="2024-05-29" version="1">MPSGEAVNNKNVVLLEQSAQLKALMSIIRCKQTKRYDFIFYSDRIIRLLIEEALNHLPMIEKTIVTPTGSEFAGLAFKGKICGVSIMRAGEAMEQALRECCRSARIGKILIQRDEETALPKLFYEKLPLDISSRYCLLLDPMLATGGSAIKAIEVLLNHGVPEDRIIFVNLISCPEVTGAVDEGLDANKYIIPGLGDFGCRYFGTDSPNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8Q4</accession>
    <name>A0AAD5U8Q4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005331</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8Q4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF69">
        <property type="entry name" value="FERRIC REDUCTION OXIDASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="515"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="561"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="9">
        <location>
            <begin position="288"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3226226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="688" mass="79221" checksum="B0BEF58A747BCECE" modified="2024-05-29" version="1">MSKSINYQKYVVNFGLGLIFLFATLYYVVYARNVRTVTVPGVVLPKDIVHICFYFMPLGILIALAQVFTPISPSTSKSTEFFNRKITTKLFGINTVGKLFFFLLLLGVNFFWWFAPLLMRDDLHEFTAIDFVDVISEKAAIAGMWDMSLSIIFYCRENKVLSYFIQDLKGKNNIDETSLNFHKIFGVMSFALISLHSVGLGFVYIYEDIAVRLIPLSRRGLLNFFGIIAWAAMIAMLVTSIYLIRRKYYKLFFWTHQLYILAVIFAVMHDSNVIYYIIPALLYLVYDKIAPRLTNSEFRNAKATIYYMDKTIVRLNITLPNNQEFPYYPPGSWVNICFPKLSKIDWHPFSITSNYLDNKKVLTIIVASKGKWSSGLVEMSADGSAVEVPVKVNGYFGNGHPFKENVRSLLVAGGTGVSALIPFTKKLLESEPNLTKFVWVVKKPADLLLYTEFLLLLQKTAKTSNFKPVFYFTRSSEVPTELHKQTQNLISENRISSKNKDVIVSETFHKKNYKLAILSLLVFIFGNLGYMVGRWIQPSKKDYDKCRKTYQTEPYLHFACYYWWSFGPLLLSVLFSILVGAITVFVYNRMFNKSTVSQNDHVEMIDNSKSDKEKEADSNQQSDLLDFVKENSRSGRPDFNELLLLLPNNSESEKKLHVYIAGPTVFNTDLQKVCRKNKVEYFVESWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8S4</accession>
    <name>A0AAD5U8S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_006975</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000064">
        <property type="protein sequence ID" value="KAJ3225330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8S4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="Sensor protein FixL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
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        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052162">
        <property type="entry name" value="Sensor_kinase/Photoreceptor"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304:SF1">
        <property type="entry name" value="PAC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304">
        <property type="entry name" value="PHYTOCHROME-LIKE PROTEIN CPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="573"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="693"/>
            <end position="766"/>
        </location>
    </feature>
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        <location>
            <begin position="769"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="10">
        <location>
            <begin position="815"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="11">
        <location>
            <begin position="889"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="35"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="400"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="470"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="404"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3225330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1048" mass="119903" checksum="6B022DE3AB01706B" modified="2024-05-29" version="1">MSCPFIPADNSPAKTFALEQSESLNKATELCSNKDLKQQALPNPVSSETSTATTTSLPTQPSTETASAAVVSPTYADEKERRLAEHVEKMDGNRHTSGGEGFKRTQKVINDNQQIEEQIFHGENEIFHKNEEAFFLAQDERELLNLKARQNEEIRALKVIQEQAIGDVNKRKAAKKFLRQQQREMKSLYNKTHEQEAACKKTEEAKQRLCEHRERCAKMADHIEEKHLKQIKQFNAAEERKINDQKILVELRVRHLTEEQRSEAMKEYQSKMNHQKALDKKKLDQICEQQRVELRHFKDKADLETLMMEEFANLLSTHELEEQEISNKHKLDYLLEKERIASTQLSLKVLLIQAENLIEIKKLQAVHRVQLRQLRRSQKSRKTKRYRHWSAILGRDLTQSKRTGSALQSGGGSSDQSADGSQGGSVASQSKPQSQAITRQSSDPNLKKSASPQINLVEGEEDEDDSQLKNINLDTQQENASDQLQKMKSQLMKLREIQEEKLEKLRKKNSNAQKEKEEEFQKMMMELEWQQDVDLKDLKKNDELEIQESIQIQERELEMEGHIRGAETKALLERKVLKSLLDSVADGVISIDPRGTIQRFNSSAEKMFGWSATQAINKNIKELMPPEFSINHDDYIYNYLTTGVKKVIGKVRQLKGLKKDGSIFPINVSVSEVVEDGFHLFTAIVRDLTEETNKEKLKQSEDDCLPQLIWKIDNSGKAMSLNKKFMEYTGLPEDQIYTVNLFSQAVIHPQDHKTALEAFMKGNKSKSAFEVKRRLKGADGTYKWFLSRGTPMFDLDGSILFWCGSCTDIDESECLQLQLSVLPESLPTILWKIDNEGNVLYSNSRFKEYTGHDFSKSIINLFSSEIIYTEDNEKVHSSFVNALKNKTFFEPTARLVSATGAFGWFLIRGTPVINSEGEVNGYFGTCTDVSAGHAKEDELHFFPESLPQLAWKCDTKGNTLYTNSKFRKFVGISDGQKFSVFSDALVHPDDLKPSKEKFIEANKEKANFEMKRRLQSENGEYKAYKTLAVPVFNERGEIISWYGTETAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9B3</accession>
    <name>A0AAD5U9B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007744</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9B3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF203">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="310"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="548"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1123" mass="128291" checksum="FD5AC0583D2AF57D" modified="2024-05-29" version="1">MSSFNALIRRVLAKQQKLKAAKGETPLAATNDKITKETKSSLRGANNSLYSIQEKFKEKNNSKKLNFFTEIDNQNLKKKKEYYSISQDNENLWDLSLKRDGNNKSLLERIVKSQTKVKKAELPNFITQKGIKGYMKFIEHYCSVKDIKLPHVATSVLRGKIINYHYRCTFQGHSFSQSSTSKDTAQRRIQVQICNHLYKLSTSEMIDDFKAANSSLKEKLEEQNKNPVKITILDLKRKNIILDDFLESKAFVVDSSKPEGFLVHHGRKKEKHFSPFFKNQLHSPKSYRDIKIPPCLNPDLPITKMYLELMQAIESNPITIISAETGAGKTTQIPQFIIKSFKYDDNRAQCIRPKILVTQPRKIAATSVAQRVATELNEHIGRTVGYNVRFDAKNPMENSPYGTITFCTSGILLRKLQEDPHLADLTHVVLDEVHERDLNTDLLLILLRRLITTTRPDLKIILMSATADTKLFQSYFAETLKASPPIIAVPGKIFPVKEHYLDDIMPMLESSIPNFNSILSDKAVAKHLENEYNPQSLKSYDGEVPLLLLESIICHICRNSAPGAILVFLPGWFEISALQKLLLQDRNNFGFNFKTKYKIHTLHSQVPLAEQNEVFNKPPDNIRKIILSTNIAETSVTINDVVYVVDSSRLRLNEYDAVRRISALNMTYASQSNIRQRSGRAGRVQPGQYFSVITKHNKMKQPYGLLPELLRVDLQNTILNTKALGLNDTFEIFKQAPEPPSLSSIRSALEQLVELGAIEKNSFELTSLGKLLVEFPCDPWIGKLLIHGVMFKCLDPMLTIVAALSNGGRGLFAIPQDPTMKMNVRRSLFEEFGETGSDTLACVHAFNKVKDKPLEYLPRYHINQSVFFNFLSTRKQFYSVLNNLGFLEDSTSGFNRQKDFFVQMNPPGAAANYMGGSFYNENSSNDKILRALLSNALYPNMAQVKDRNTYIGKHNEKLLLAAGSVCKIRGGDDSEEGSLTEVEAEAFPSRFLSFQEKQKIDMRVYMRNCTKTSILPLVFFNDFSLKEEKKIFRSNKENQNEKKIIIFDNWLKLDFGDIQEKNELNLKNELKFVLKLKHVFALYRNYFYHYKGNFGFWEKEGTEFVDLLVELIEESDTEEADND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9R6</accession>
    <name>A0AAD5U9R6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039867">
        <property type="entry name" value="Furry/Tao3/Mor2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12295">
        <property type="entry name" value="FURRY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12295:SF30">
        <property type="entry name" value="PROTEIN FURRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2227" mass="253451" checksum="C5BFEC3C809B8482" modified="2024-05-29" version="1">MYKAAPIAADQVDVEQLYINKLRISMNEMIVAKEEAIRMENYGLADQLRIKLTSLQLQLIKSEHQFNADLLTNFVTVWQDGIIQFISKSLYYKEKTGKPPYISSSFPSKEPFQCNFVESIGCFPTKYYDSFIRSICLIIPVDSPDNFVKSPFGFEFFIRKLGTLTKNQENLDLVRFITTLCCFDILLRITGNINETSVDINTLEILLKHCQNYIKFFKRGTSDIERMLFEKISTRLSIIVGDLALIDRSMVIKHIYSLVDHNKKSTSEEMLLVLSTTRYISSKPVTSNDFNELLYLINELCLHFEKNKKTIIRISIILSLERIIQPIDLTSFFPRESYEIALVNEISEIAKKARKWMKDDDLKACCTRLLGIILINSKSDYFGQNYDSYINNDLFPKSKIKSFAYECALQILRGQYYLETLNNSRNRVTGNFSISDSYSYLTRPRIEEVREATDNRIRDLSEKLFVRRKGPIGLENLNTCVQIVVQMAAQSFPLTLRLISHLLESKNSDTNIRFEENFIGVHVLYIIINKSSKFCPMGYSVDDANYKDLLASTMREYEVYLPKIFLSCEPIVGIATLGKSTAVLEKTQFKLEEALEWKNNRNASDKSKSNKDSVNLFEDDIFNAISEAIDHANTGSNPNIAEKDTPVNPVVDSYSYGTHSRMASEDERLDNVTTEFESTDELNRKVSSSIKIWHEMCNKADNTILNVERVVDSLKVSLPQSKRKSPRITKPEVELVVKLMKELIKLIPFMPLPELTGKKFLIGSYLIHSIVDISHQVAITLQTIFAKHSMQRLEIINGFLNFLKFSQVNDDISICTTLTQLSHLLYLWSKKEIPPLYDTERDAFYRSSCKIDAAMMLMFARPNSQIRKLAIKILADYNSIVEQIFPLSHPLQPGQFPLFHILATEVDISRWALYAYLEDNFQGNCLEPSISSSLPLLSFADVAASDYAGLFKFYLGELVRQFAAAGRSKALRHCVKWLKHIAIPELTSTTNFTPDVYSAYSAYLVLLFGLAGVPEKSETHYTIRAVASPENLLLSTFRGYVPSVLNSENEAEIKAVTSASYFLHRSVFQLLISNLLQWYNDSKKTKMSHRLMDNLLLLLRFSAQSPEFRSVIREPPLFVSSLIDILSEFLLLAENALNDVSFLQTGPVFRLQSAINYCVINQRLAESLSSSESLYSIQRLSEDYEKNEPDSKVEVSRFVSILSMGGILNALDNVQNTGVKLNWKVSFRRACLFRFKEWYSIALEVSSVMSSNENINMNQSRYKLMRIIGFAIEKVLSVPGNIFENSPIPQDLIVWLTKMESSGYSGPTQSKSLIFTQAIFDQIISRRVEGPELFLSGEDVTIPNSAKDYISTLHGLPYEDGLSTNEHFSCIVPKEIVLKLRPNLGGLLYFGLYNMLNNNKLVRIRSFLFTRELFKTFLVDSELKVEEYFKSLQGIFYSSVGHLLKKCIKKISEVASKYFSEEALGFLWEAVRCYRTTPKSEKQFCLMIPQIWILELIIPWCKYIDLAAVGSSVINSEIFKFLMDSVFNNPHSGEELVRSCWMEIVKTPTFGADNIEVFSTVLVQICGKIDSVREITLEMAAALYEHGHDIMAPFISQFLSKDFLPWKPSKFHPSTNFVKDYVKSLYKDLGGSNLEITNEYSMTCKAAVMLISELSLQNFEPLIPHLPVILNFISIQLPTRLQENTVSTFLLLNLIEGFVCYLHSKQKIFETAHNESVAQLKKMLLLFEISVCAVEDTVSIKSTRALKISMAQFIETLLIVFNVEYPNLRRDLSTEVLGWCCESYLTADQSTRAITIYLNLMKGSVLDIQCLNSRFFDQIAALANIEIEMMEASADETILPVPPPKSPLIGRTSLSRGGALVSKSLTSFSKETWSNLGESKLQVKKSSCAILIALLNLHKEVIATAKGIDLLSSPLLFWISVSIFNLPFSSFADVYTLALENCIAYLGKLNKSVVEYGSGANSFLNCFERISNEFSGIQPLLLKSFFSKEEKKKTKDKSNVEFLSFNLLFESWMVLPEEIVDKNSVGFFYSILYGITWVLNRVSIDGSKISRIDVEVETISKQLKELLISTNEEKFADLIMALQLISENKLSVNSFDDVIFISMKNIFDIFIPDFAINISDFFVYGLNLGSDYSKVILKMNHAIWTCAKAKYGANESMEYSTILRPFKVFVKRLPFFNENFEEIKSLVNFVLSESEEVNVNAVTQIDLTSQGRTDFFPVMENSVGSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBF5</accession>
    <name>A0AAD5UBF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial DNA polymerase catalytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MIP1</name>
        <name evidence="10" type="ORF">HK099_001142</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005760">
        <property type="term" value="C:gamma DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002297">
        <property type="entry name" value="DNA-dir_DNA_pol_A_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041336">
        <property type="entry name" value="DNApol_Exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267:SF0">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18136">
        <property type="entry name" value="DNApol_Exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00867">
        <property type="entry name" value="DNAPOLG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1865"/>
            <end position="1887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1899"/>
            <end position="1923"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1935"/>
            <end position="1958"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1970"/>
            <end position="1988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1994"/>
            <end position="2014"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2026"/>
            <end position="2043"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2049"/>
            <end position="2066"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2115"/>
            <end position="2137"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="9">
        <location>
            <begin position="671"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="Polymerase/histidinol phosphatase N-terminal" evidence="8">
        <location>
            <begin position="2147"/>
            <end position="2217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1138"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1175"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1283"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1383"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1414"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1595"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1149"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1175"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1191"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1206"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1287"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1297"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1391"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1414"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1440"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1455"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1472"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1602"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1615"/>
            <end position="1636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2338" mass="264847" checksum="70C771BEE442B112" modified="2024-05-29" version="1">MFSRWFLNIKKNIIIVKCRFSSSSVTANEVGIQLLPEYLRCDLFPKTATDFSNKKYADLSKLILKHQNLLGKNSKPLPDMNFLLPSLTGSDIEQHFEVISKFYCKEYLQLSEALIKNKQPVILLEKLLKETKWNMDAGWTRYPLNGKICKVDFPLEKSLVLDVEVLVSDGPFPIMATAASTEAWYGWVSPKLSRQLKKMRKTAKDLNSLIPLGPRNEEKIIVGHNVGYDRIRLKDGYSMEVSKTRYIDTMSLHMCVGGLSNQQRPFWQKYKNLREKKNEAETEEEKFMKEAELRSIEQPWLPLVATNSLKEVSYLYLGISMDKSVRNVFVDGNIDEIVDRFQELMNYCANDVLITYKLYRELFPLYRKKCPSDVTFFGMLEMSTGFLPVTEDWEKFIKKADKIVENYNNVIEQNLTSSVEKALTFQEDERWKSDPWLKNLDWTVKEKRNKNPNLVGKPQWWRDLWCPKEQQIKITTKKRITPYLLNLCYLDYPLYHSKKFGWTFKVPKENKLKLFKKIVSSNPSSPEAVDEKVVDKEFDKNIYLDREKFNYFKLPHKDGEGKNCGNPLSKQFLSCFESGVLGSNSANTIDLLKKTSQMSYWAGARNRIVSQVVIWNDIKNGKGDLQDMIARDRKSNCGVILPQTVPMGTVTRRAVEPLWMTAANAKLNSIGSELKAKIQAPFGYKFVGADVDSEELWIASLLGDSQFGIHGSTPLGFMTLQGSTDMHSVTAKILDISRDNAKVFNYARIYGAQQNFAENILKQFSPNLEKSEIKSKSLKLYKETKGVWMGSKSRNAESGYWSGGSESYTFNKLEEIARMEEPETPALKCKIPEGLSPSNLISSRDFLKSRVNWVVQSSGVDYLHLLLISMRYLCNIMNIDARFILSIHDEVRFMVKENGKNEYLAALALQISNVWTRAVLVNAVGKFFELHTLTVSLGMKDLPLSIAFFSAVDVDHCLRKEVTTDCLTLSNDIPEAKGESLDIYQILQKLNVNLDNSKEIYFEDTVPGLKDFIKFELHRKNQEVIGTDNRKVNSKFLSNFDKLLNQFPAVKPFFKDDEVSKRKYTNRNEQKVLNFDVNKRNILDDVEKPSIMPVLKNVKNPKFKDILTFNTKEVKFKNLTINERFLAVKKELPLESGEQKEINAGGRSPLTQKSSKVVSSKDITVLKEDKKLNLNNSSTSNELKGLPLASGPSNNTNSPKQIKKSKLTENIDEINRNESNDNYQRNVKNVEKKINSDIQPSIASNNKNNPVRSTAHINVKQISSDNLSEDFQTNMDYRNDSLNVASKEQRKSEGKNISKSNSQNNLNADTKSTTDKNIVKSKSQGSNLHKVVEKDFGKSDSQPSKPLKDNEKILVTSNSQISSLNKDIKKIIKSESQPNLKNANIEKSMKITHSQQKSKEAISNSEMDIIAAKKAESCSDGGEKKRIRSDPPLAFNETKSGMEYKKPNEKVVTEKLNSQKKLSDSTKGTQSKQKDLMKSASLDKLDQKTSVPLKSKLRSELEKVSTNDDIKNELKQLKSELLKEKSQPLLTTNQKLENEKLILKKNDQNPKIIDINSSKSLLKAKNSDDSFLNKSIQNKNQLLQPEELKIESQRQRLMDQNSASSSYSSGGHMRSSSETREKDRKESTVRFTKDAKNTSLLPSQSSLNFDNSDLAEISTGKSIRKKIKNNSSVRSRFDENGVYLPSYQLQNLARVNRLTARGRPEIFVPQGTLSRSQGASLRLKNLQKDAEKRLRIENYKKKLAETASDLNLKKKSKEYGEEEILPERTIRYNQSLRGTLKRASVAASYFTRNERASTIGPAGNLGNLPMFKNYNSNLTALGLNSFRQATVEIDETPSKFWIFVDDIISMDAERYINYFPEDNDLPVPITLSFTIIMVILFILMIIMGDPEGKRGFAPYIVNPMIGPTFYTQIMFGGSIAVWIRNDFKANWWRLFNASFLHAGIIHILINGSALLIMGPKIDRWFGIGRVFVLFILCSVGAQIFDALLRTELVVAVGASGTICGLVGVIIADNIKNWDAINLPKMQLGYWMTQIIVFFAFGFLPLVDNIVHVGGFITGIFTGLLIVPRLKAVEDNMDLETCCISSEASLVDTDSLKNPGQRINQKLYQNLDIRNIILTTIGLIGTLFIFIFLTYLLWIDYEVGVPVLYTHIHSTASDGKLNPRQVAEWAVASGYNAIIVTDHNSVDGALQVKKFVEEDPLFSKQLIVIPGMEYTSCTVHMNFLNINETIPLCSDGSNYCPVQTLDMIKFLVDKVHGLGGWVSINHIPWSVKQEGGRLVSTLPNQPTLDSLIEIGIDAGIGQFLKAHFNVCLVEIVNGDIFDLPSYQKALSTGLGMFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBM3</accession>
    <name>A0AAD5UBM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BLOC-1-related complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBM3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12782" checksum="A0829F7FC80610A9" modified="2024-05-29" version="1">MSIEGSIHSPLRRTSENQQQTDVLLNSKLHLKAQQEELIKNFSDISYTTLNELNISEQISKAILKFRQADVIINKTALSLQKVSEDTKTNLIVAKEISSILKSTVSVGEQNENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC16</accession>
    <name>A0AAD5UC16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC16"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052969">
        <property type="entry name" value="Thr-specific_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47763">
        <property type="entry name" value="ALPHA-PROTEIN KINASE VWKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="1">
        <location>
            <begin position="15"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="815" mass="92655" checksum="248B858629B0E2C5" modified="2024-05-29" version="1">MSSSSSASNNFTYQADGSIWSFTQSDDQINIQQVIPVNVKPEVKFENNYVYCKLPTEKLPRLDGELYGTVLPFDSIWQLEAISDDQNHKLMTIHLEKSPESIGQVWPLLIKKGKSEEMGCDIQSLYEIGSNAHLSGDVNKAVKYLQVSAEKGCISAQLKLAAWYEIGNGEEYKQYNFPLKKDQAASHQWHKEVYDKYELIYSFFDVKAALLGNAEACYVVATTYLHGTHGVSQDYVEAVKFFKKVYETVNIHKTLPNIYISASFQLGLMFMEGGHGLGDPNPKESLIYWKLSGMAGHPDSIFNIGVFYLNAFGVDQDIPGAIEMIKLARQANPSLNLPPPLLGLSEVELNKYVELSKTIKRGENQEIQDYLKSLVVEVKKLNVKEIENSNDEIKFVQQKKKSNKGKNLKKKKKSKGATFSDEVEDEKIYSFFNLRTLLIVSVLSVGLIVWVNRKKEIQNKFNSLGLQFLQPKDDLVKKKLKTFNQPTYTTTATENYSGLESSLKPPQRNASFVIPPRNASENNPPIRSSSKNVQLPSAINNTSAYDDLYDFRQEYISNSHYSHRQLALNDAVMHNYSNYLPSYLPIKNLKTCTTDVAFLLNLAGNAQSTINLLKASINRTVFELDQKYSYAEIRMAFVGFTDFGVDGLSHYLIKDFCTVTEFIIFLNENVNLQNEPFDKADDFLGGLKRTLDLSWKSKSKTLILITERPGHGEEFNNYGLHDDRYFNSDDPNGLKSEFDLTKILQKYLNLNINLYFFHLSDETLKMEAKINFILTELKSSLFGWDLKKILKNKNLLFESLLSSITISIKNAENFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSV7</accession>
    <name>A0AAD5XSV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001030">
        <property type="protein sequence ID" value="KAJ3207822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSV7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="63"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="207"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="286"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="474" mass="56406" checksum="DB332D2A5CE6C3BE" modified="2024-05-29" version="1" fragment="single">MLSTHNQPNNDPEYTEFLGYLLDLHNCDYGLDDPTSVIKVSFMDHLLRQPNHVQILNPINRQRLEVERERQLLLKRLKNLEFKDNVLKNQEDSIKKLLARREIVKKRKFENHLTHQRQLFNELNEFIHFLHNHEPEEEGMSKEELDNVLEEKKILNEAKKNQIGVLNSNVLHQEFLKYLKNLNGEIYDDENEEALLERIERPRDIPHEKMLDELKFFQEKARRLEEIREKRQKGFKKNEELAKKQNLKKEELDDMCREYEKKQLHYDILARNAKEKISVEKDDNIKEKYVNNLKEAELLRDGMEKKIEKIIQAEKEINKNIGFEKKEKAEFGLGDNEHPENVGNNSRKAPVEKFDNQNEDGEVVNKNHDDAVQLLKDNEKESVDQEEILKNINLLNKINYQLKELSFTEKILNGIINSKNLDKVESTSILKLEEDLNKILLQLDLIESFENEIIRSKRHELVEKINCKLDKIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTA3</accession>
    <name>A0AAD5XTA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008053</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000845">
        <property type="protein sequence ID" value="KAJ3211263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTA3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3211263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="446" mass="51608" checksum="71010E8C4383C4A8" modified="2024-05-29" version="1">MKTTSCRWLNCNHPPFETELDCYNHIKLQHTKSGPQSCRWIIEKNSNINPQSSIHNPQDALSLCDIDSKHRGHFVEHIVSHFSFNLRPLNCSHCGETFRNRQDFKRHEKLNHPNETVRPSFESYESEKSEQNNTQKFDTQKKLNSFPISNYLEVSSHHKIRRNSMIDFNTNQQNYVLKSQTVDFQPLPYSAVGLTPSFFKRYCTVLMDHQLVLPANMLSIIENVNKQGGRIPPFIETELIVELINSHQISLSGLTFVYSEAGKFLLADTLIKKFNEKSQKIWEDFKLIEKSQTSKLFSQKKKSARHYLKSTLVSLLQLFWKTWKLEVTNEDDGQLVERTASVFSKSSNESYSVGLQVTINHQVDFISLSNRKSMFYNSLNYFKEEVESKLEIKSSDGVEKIIISTRIVDFPGPKFIIWFKFGTISNETSQDNGSRNGPLTLLGFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTX5</accession>
    <name>A0AAD5XTX5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">beta-glucosidase</fullName>
            <ecNumber evidence="9">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007121</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000665">
        <property type="protein sequence ID" value="KAJ3213921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTX5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF12">
        <property type="entry name" value="BETA-GLUCOSIDASE G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Fibronectin type III-like" evidence="10">
        <location>
            <begin position="616"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3213921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="669" mass="75234" checksum="B06253023AB17A1F" modified="2024-05-29" version="1" fragment="single">MKFNCDKKKCFLTFLVSSISIAISFFCFTKDKTTESIKLKPLTKTDVAPKRSWENAEKLALETLSLLTLKEKYYLISGTDGPHGLRFQNFQSASSFTSSLSLAATFNKNLMFEYGNAQGEEFRGKGVNVALGPMVNMHRSPNAGRNFEGFGEDSFLTSIAASQVIKDTGSYSEIDERALHEVYLAPFKKAIEVGVSSIMCSYNKILSPNGELNWACENEYMLNNILKTKLKFKGFVVSDWWAVHDEKLATQNGLDMKMPGDNFWNSPFYFLKVYGLKNLGEKIEEARLNEMTKRILTSWYQIGQDEPGFPQVNFHSFKPHLDQGIDVKGNHSSVIRNIGSESIVLLKNNFDILPLNRNQKIFVFGKSALSSADPNKFPDRAGVDKHVAQGWGSSSTNYPYLISPLEGIMKNSEHVKYVDWEQENYQGMVENDIAICFVYALSGEGYLNVNGNAGDRNDLKLWDDGEDMINKVSSLNKNVIVVVVAPGQVDMTDWNDNVAGILYSFYLGQESGNAIADVLFGMVNPSGKLPVTIGKNSEGYCCSVNFKSPGDVKYVESIFIGYKWFDKKSIDPLYSFGFGLSYTKFNLSEISVSETVEKNFKIEVYLKNIGTLSGAEVLQIYLTFPNYVEAAKFNLKGFEKVKLEVEESKKIEFILDRKEHLSFFNVTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU28</accession>
    <name>A0AAD5XU28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Brl1/Brr6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000626">
        <property type="protein sequence ID" value="KAJ3214376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU28"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006998">
        <property type="term" value="P:nuclear envelope organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040202">
        <property type="entry name" value="Brl1/Brr6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018767">
        <property type="entry name" value="Brl1/Brr6_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136:SF1">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRR6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10104">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01042">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brl1/Brr6" evidence="1">
        <location>
            <begin position="162"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="256" mass="30260" checksum="5926F7FAC6D72AA8" modified="2024-05-29" version="1">MIKFYSHLNNNFEEDLDFDQENTNYYRGKEAPMDFEYTHSKFQSNFLLSENKNQLRNPNKNTAPDENKNINIPEEKINDTKKSNENAFNFDLNKLNLEAEEKNSQINFKNKLKSLKSEKSFSRKRKKLNVMNDEENDDELSDEDFNKYDGSKIAAKLNKRSFQDHLGFLHDLNMKAEEYSLEIVYQISECSKLYVENNCDPKVRIPYMKEVCNNWEICMMKDPKEVAKMKIGVEVFAEILNKLVEPLSYKSMVSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUC6</accession>
    <name>A0AAD5XUC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006311</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000537">
        <property type="protein sequence ID" value="KAJ3215534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUC6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="432"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="296"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3215534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="538" mass="59346" checksum="0850FF8A9B28DC33" modified="2024-05-29" version="1">MASSCTILPESSLCSSNFVGTPVFTDIFTNELNGKFTDSANYFGHEKTLNRFKTNFGCTGADLENSIKYRRYHATLQCAVWVQDAVKAGCSGTPGIIAEYSLCPDRCDAGVEFTEKTLNNNTLCPPSSDPAITAAKTKFLNDQRNYCEASKVFLLREGTITCGFAEIHEEVYCGFTSKEIGASECNTNVNLLDLPCCKRFFKEFPTLKVNTTGGDLTTTTLSATISNSADIDATPRSSITLGIIEISGIVIALIFFVIALVLCLITKSKKKKVNELKKSQTNIPFTQRENVRESCVVDSNNNSSSENYRQTPPQNPSPASPFVDSINSNHYAQNLNYLLNYERQIHQRLSQQSQQQPYQQYEHPTYKEPLHRDAFFSETATISTVAANTNVSEVSISSPVIKPEDLGCGITNFSAQTFSTHTPSLSNSTITTQQQKLLVIMDYLPTQYDELTLKKGAILTFVSGFDDGWAVGIDTATGLQGVFPLVCVKKIEEPTIFLPVVCSNNATKNNESPVTSNPYLQEPPDYLTICKRKSSKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUD3</accession>
    <name>A0AAD5XUD3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_006383</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000546">
        <property type="protein sequence ID" value="KAJ3215391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUD3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004868">
        <property type="entry name" value="DNA-dir_DNA_pol_B_mt/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03175">
        <property type="entry name" value="DNA_pol_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B mitochondria/virus" evidence="9">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="65" mass="7585" checksum="2421D95A65EB7773" modified="2024-05-29" version="1" fragment="single">MTVFRSKFYDSNIQIPIVKRSFNVDIKQAYYGGHVDVYKPFSSTGKAYYYDINSLYPTAMLKDMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUQ1</accession>
    <name>A0AAD5XUQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001711">
        <property type="protein sequence ID" value="KAJ3201546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUQ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3201546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="226" mass="25865" checksum="315B8B6D49CA9A57" modified="2024-05-29" version="1">MVTFMLKLTDFPSAASIFYVAVLLLDLIQSRTTDKYLHLSKAAISLVLIWLDFYLRKHQTYFEPAPATDGYRHKSLEMKAGILSILTFNWLTPLISVGNKRILTEDDLWELNECDLSENSLARFQEVKKNSKTKNLYLLILYTIWKPFILQLIFGMVETALGLSGPFFLNKILKWIQCKEDTAFGGWGFLAAMFSCSIIKTLVDGQLQFSARRMGIQGKKKKTEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV83</accession>
    <name>A0AAD5XV83_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GDI1_1</name>
        <name evidence="3" type="ORF">HK099_005001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000373">
        <property type="protein sequence ID" value="KAJ3218574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV83"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="197" mass="22351" checksum="5DF2E98028C48866" modified="2024-05-29" version="1" fragment="single">LDTKIDEILYDEANKVTGIRSGDDIAKCHMIISEPRYFPEKVKISEGKKVCRIICFLKSPIPNTNESNSCQIILPSTQIPKRKNDIYITCVADKHLVCPKGYFIAIISTICETDDPKAECKPALDILGPVTDMIVEVKELYEPISDGKDDNVFITKSLDSTSHFETVSQDVKDLYFRIYNENLKLNGKYSQVYESEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVS4</accession>
    <name>A0AAD5XVS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">T-complex protein 1 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CCT3</name>
        <name evidence="14" type="ORF">HK099_008594</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000961">
        <property type="protein sequence ID" value="KAJ3209069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03337">
        <property type="entry name" value="TCP1_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000073">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000085">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000005">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012719">
        <property type="entry name" value="Chap_CCT_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02344">
        <property type="entry name" value="chap_CCT_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="544"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3209069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="569" mass="62821" checksum="2514572F2BA0C5A2" modified="2024-05-29" version="1">MHQVTTKEFYPKGYGGGNVMVMNMNMQRETGRKAQTSNITAAKTVSDIIRTCLGPRAMLKMLLDPMGGIVLTNDGNAILREVEVAHPAAKSMIELSRTQDEEVGDGTTSVIILAGEVLSSALPYLERKIHPIVIIRAYKRALEDSLAIIESCSKKVDTENEAEMLDLIKSSIGTKFAAQWSELMCKLALKAVKTVCVETEIGQDLTKREIDIKRYARVEKIPGGEVEESCVLDGVMVNKDVTHPKMRRYIKNPRVVLLDCPLEYKKGESQTNVEVTDESHWARLLEIEEEQVKELCDQIIKLKPDLVFTEKGVSDLAQHYFIKANITAIRRVRKTDNNRIARATGATIVNRVEDLKESDVGTECGLFEIKKIGDEYFSYLVECKNPKACTVVLRGASKDIINEVERNLQDAMCVARNVYQHPSLCPGGGATEMTLSVKLAEKGKLIGGVEQWPYRALAEAFEVIPRTLIQNCGGNAIRILTQLKAKHASGEHTWGIDGCAGKVVDMKEYGVWEPYVVKAQTVKTAIESACLLLRVDDIVSGVSKKGENPSSAQAMQAAQDGEIPDAEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVW1</accession>
    <name>A0AAD5XVW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ddb1 and cul4 associated factor 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">DCAF7</name>
        <name evidence="5" type="ORF">HK099_008388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000914">
        <property type="protein sequence ID" value="KAJ3209986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVW1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045159">
        <property type="entry name" value="DCAF7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19919">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="163"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="274"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3209986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="356" mass="39429" checksum="C2ED222B82C9B85A" modified="2024-05-29" version="1">MDLKKEQYKYVAPWQVYALNWSAKPGQFKLGFGSFVEEYKNQISVTTLRNNELVHLATADVNYPVTKLMWSPSKAAGPDLLATTGDYLRIWDLKQEEHELPQLVSRTRLGNNRRAVPNQKKEISAPLTSFDWNEADPSMIVTSSIDTTCTVWNIETGQAKTQLIAHDKHVFDVAFAKGTDIFASVGADGSVRMFDLRALEHSTILYETPPQNSTTKTDLQSAQQKGGANLTDPTPLLRLTWSKQDPNYIATFQANSNSVIILDVRTPATPVSTINGHTKAVNSVAWAPHSSGYLCSAGDDSQALIWDLSQMSKTKVVQDPILAFTAEGEINQLAWNNVFSDWIAITVGNTIQALRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW06</accession>
    <name>A0AAD5XW06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_008098</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000856">
        <property type="protein sequence ID" value="KAJ3211091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW06"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000335">
        <property type="entry name" value="ATP binding cassette subfamily A member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="486"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3211091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="829" mass="92907" checksum="2B796C2358C9777C" modified="2024-05-29" version="1" fragment="single">MSLFFIQLTALLRTRLILLKRNLNSSLVLIIFPIYYVALSIIISTFTSPFSGIEKQPVSLSPKVDNTLQLAYSLQNHFPESTWNEIKSNTTSSFLLNENVSPSFTNFGSLDVYAQEFKSFLKNRKSKYDNNFPVGGYSFNSTPMQLNENFYYSTTLFRSSKATDNFLYSVLLKNLNSAMFNVATKNTTLASTSFLQINPSISLFAERSTFDISAFLIPLLFCFGITFFLPILTQKAVQELEEGFTQQLFIMGCKKEVYYLAFYFADIILMLVPLTINHIILFGVGAKVFTQTSVFAFTLPLLFFGFSAVALSYLLSFLIPVGVKATLVSPILGFVNTLIIGVPAVLLQFVFKEVTYTSSLIIHALVPHLGIVNVMMNVGTSFSMGTPITIQDVFDIKKIIFPTLIIFLLQTLFYFYITMKLSEMRWSQKNQDSRLITRFLKLFKNHPVKSQDEEATTNLTDVVGDQGVKKEMQDLSQETNNDEYILKIKGFTKSFPIKEAKEDKIVLDNLWLGVKNNECLGFLGPNGAGKTTCMKILIGLENANSGSATIGGMSTSPYDPKIKEIVGFCPQSDVLFPELTPLEHLKLYNGIRGITDEKEVDERIKIYCLEENINVKVKDLSGGNKRKLSIAIATVGSPKLIFLDEPTTGIDIAARRSIWDAINKLKLKSSLILTSHSMEEVEYLSDRIGILVNGKLRCLGTSNKLKSLYGNGFLIKVKLNSVTEIEVVSKEIIDTLNLNFKDFGYHCTIQNIFGISCSFSLKQLDEPKFFTTKKDKIDIDKDKKLLNSTTSSSPPSSAVIISNIFETFEKLSLKLGNIDYTVTQTDLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW07</accession>
    <name>A0AAD5XW07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ubiquitinyl hydrolase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003821</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000256">
        <property type="protein sequence ID" value="KAJ3221043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW07"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000396">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF10">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="6">
        <location>
            <begin position="3"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="6">
        <location>
            <begin position="151"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="5">
        <location>
            <begin position="314"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="58316" checksum="83967B8C5094AE90" modified="2024-05-29" version="1">MSEICNHPKSLNLPTQYSKIYKDECTLCFDSQDSDCGINVCLTCFNGSCISNSHTNLHFNKTNHPLVVNIKRIKKVRDPGTPPPQKLTKIEIKAENEADLYEFVTKPICLPCGNVEINRSEGNINAVIESVLNSLSAKKQSEIKAWEEDITSCKHTKEVVQEENVQLSNHAQAHCVNCELKENLWLCLTCGNLACGRQQYGIIVFDILLTKVGGMGGNGHGLQHFEQAGHSVAVKLGTITPEGQADVFCYSCGEERLDPLLGQHLGNIGIKIADQQKTEKTLTELQVEQNLKFDFSMATEDGKTFTPLFGSGLTGLKNLGNTCYMASVLQTLFSISKFQDRYINLSKSHHEHCGSIPAECFHCQICKLADGLLSGRYSSREKQVTTTEEGKEVIIQQGISPSMFKNLIGKGHPEFSTMKQQDSQDYLTHLLSIIEQKENNNIANPTKIFNVSFEQKLQCLECLNVKYTSSAETGILHLFMNTKNNDEKESIKFEDCLDDYFSESRSEGWNCPRDKKPTTCVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW40</accession>
    <name>A0AAD5XW40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000251">
        <property type="protein sequence ID" value="KAJ3221102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW40"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="177" mass="19671" checksum="8B5842C34FB9CED1" modified="2024-05-29" version="1">MASCHSLPFTVFIDMAIGPILRMASSRMSSLLQDLNDFNFENDAEPENNIPEIPKRGESSRRTFDRKSSNQTPFSERKASNTTPPISERKSSTTANSINGRTSVRTVNSNATTLNRSNNENNNIPVSYLDSVKILVETIQQKAGDKREKIDSNDKRSRKFSSISNSTSASDNFDSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW54</accession>
    <name>A0AAD5XW54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nuclear mRNA export, poly(A)+RNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MEX67_2</name>
        <name evidence="11" type="ORF">HK099_003614</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NXF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000239">
        <property type="protein sequence ID" value="KAJ3221287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW54"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14342">
        <property type="entry name" value="UBA_TAP-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057125">
        <property type="entry name" value="NXF1/2/3/5-like_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030217">
        <property type="entry name" value="NXF_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005637">
        <property type="entry name" value="TAP_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662:SF22">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24048">
        <property type="entry name" value="LRR_NXF1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22602">
        <property type="entry name" value="NXF_NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03943">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00804">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51281">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="9">
        <location>
            <begin position="333"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="TAP-C" evidence="10">
        <location>
            <begin position="543"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="599" mass="67944" checksum="B2656B60C4E93E36" modified="2024-05-29" version="1">MDRKYKGSVHSRLGRKNSPTYITNENGKIQMKVILSETVNDLPEHLINFLNSELEKKDQKACNFSDVRLDGDKTVFLSVAHFGEAQKLTKLSGIKMGKIKLHVSILQRKHHKNKPDSSTTAVTIQKVKDFCSLRYDPMSKILNLNAIDKELAPTGFQVFNDASGKSKSGAVLLKIISEAFPEVECITLEENQISSLSTLVSLPQRIPNIISLSLKNNNIKNFKDLEKLPGKSLKRLKQLKLDGNPIKENFFRNKMKLSKSGLRNPGDEEEAKLNFYNFAKKIFPTILSLDDYVYPIEQNVVFGTKFDILNVEKAFFDLPATQEVALNFMTKLQLLDFYDEFSTFSLSINSVKPKGASYKGFDNLDGWKDADRSHTKENSKESRISNLIRVGPKNILENFLSLPNTIHDVSVVNDKTSKIFVESFKINENTILITVHGEFLDLKIKNLKRSFDRTFLLRGNAACHDAFKILSDTLCLRVHNKNPEFLKFSTQKSQTTQNPVPIFNFAVEHVPNLVVDNLPSLPPQLGSDLQNLIKYQMGFNLNNEQHLKVLQFSNLSGLNYAFSYQCLMESAWNYEIGLQNFQNVKASIPPNAFQFDPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW76</accession>
    <name>A0AAD5XW76_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000785">
        <property type="protein sequence ID" value="KAJ3212320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW76"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053287">
        <property type="entry name" value="PP2C-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21586:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21586">
        <property type="entry name" value="TIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="662" mass="74567" checksum="531BA285A1CF2529" modified="2024-05-29" version="1">MFQKQTDSPASITTAVYSHVEMIHKELTLKYNDEKTTPLEIQLILNRLENIFFRFQMELYFVESLILLYKKFLEKMFQKKSKITSQHFKNFPTVFIKNSTFNAEPVSVRRHPVDSRWDFLALKVNGRTVPFGDKGHPLTDFCALEETSINNLECMLTATYGWITKKPTTTLPSTPNFAKLKKPGFSSSTLSSNKSLSNGSNATVSDTASASESSSINNSSNNSRSGSIANFKMESTNPYIKDGKVLINDPNNDGYLVYVFKGLTVGCVIDGSGSGLRAKLAGNLVLATVNDLLPELKQLFLDNSSKKISSMELHKWLQKVIIESHIKIKSISEAGSTTLIAYVLTELEEPIDDDKLLLCYLASGDVEAFHCSHKRNLWSNLLKEPCQFTKLRFDTSITPGGVGGYHGDEESIYGLYFWKNEDWGKNMDSKPKSSKTNNLHFGQILINPSDKLIFATDGLGDAIDPIRIFLRPSCALKSLSYLNDQIFFDRFEKKLLSPKVDKAVLKDWLVFGKAITFSAMEVNDLKNLIFNKFINDDSTKKTNVVEEGAESSGNIENLMDRMVINNTEVQKEKNGNEEILSASEILNKCVDFAFYTTEGSRKIGEDSFGTATEENWTCAIKKYWDRRNKMKINENTDWKSFVANFAKPDHLGIVCFNANIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWJ5</accession>
    <name>A0AAD5XWJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000672">
        <property type="protein sequence ID" value="KAJ3213831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWJ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="369" mass="42942" checksum="FDAFBDBE4DEC7881" modified="2024-05-29" version="1">MSERKDRYLFTDIPIATSNVIRVTISVVSSLLNLFLFLWAIRKYRKTQNKKVKQYLVFIMIATFFFIISFVANIFIITQKFGGDALDNMTLEDVKKLPVEKIWEILDASDREAHWKQFVQLISLNIGLYFYLLMVQKRFSLSKNIIAYSKKWDYFLIALTTLVFSSYIVFTSVRHYYCLLLDRYETDKCQPLYTIAFRYQASLFGYFCFVDVLLGVLLLRFIQALSSKHVNATNIARALKLKKRVTAFIVIWIFAIIISLALFTIHVLYREKFPPNTWWLIFDIGDLLIAIEFLLAVEYFHLITALTKLTAPQSMFGTSTSGFISSDREEITFSSDDKNTSKTLNSSQINTLPVDDSLKYSIKDESLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWM6</accession>
    <name>A0AAD5XWM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001737">
        <property type="protein sequence ID" value="KAJ3201375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWM6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="59" mass="6389" checksum="24162D72C55258F0" modified="2024-05-29" version="1" fragment="single">KTPVTAYLMQELLLVKTSTISNIIHSNTVHNSIQTIFSGNVDDSTGITPNISTQSIVNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWX3</accession>
    <name>A0AAD5XWX3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000919">
        <property type="protein sequence ID" value="KAJ3209872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWX3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3209872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="14106" checksum="2A93714C97BDE213" modified="2024-05-29" version="1" fragment="single">MLKVNTEQETNGTLTRTIRSLNNEITKIENLPASFTSLDCNWNEITKIENLPDSLTQFSCASNQVTRIENLPDSLTELNFDENPVKNLDDVDISRLNFSLDDLSVFFTHYKAIKRIQKRIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXQ6</accession>
    <name>A0AAD5XXQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Stress response protein NST1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Stress response protein nst1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NST1</name>
        <name evidence="9" type="ORF">HK099_007167</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000672">
        <property type="protein sequence ID" value="KAJ3213830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXQ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025279">
        <property type="entry name" value="NST1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13945">
        <property type="entry name" value="NST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="121"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="188"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="325"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="31"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3213830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="801" mass="93796" checksum="AA00E90CE90B6F58" modified="2024-05-29" version="1">MQNLNSIWNADKPEKERIRAFWLDLSEYERKQLVKLEKEAVLKKIKEQQKQACSCSVCGRKRSVIEEELEILYDAYYEELENFANDQAKGQTNPHPHSQLRNFSKSIYLLILNLKKDRRYHHSHHHDEEDEEDSEDEYDQESEENGSMHEFGSSLTVKGGILTVADDFLKNDGKKFLDLMEQLAEKKMRQMDDENNDSDWGRNYDEEEDEEDEEYEDEDEALTEEQRMEEGRRMFQIFAAKMFEQRVLAAYREKVAQECAAQLLNEEAERERQLQLREEKKQKLLEKKRLKKKLEKQKKDEEKERLERERQIEEERIRVEKEKALEAERQRREAERQKKETERLKREEAERIKREAERLKKEEEKRKQKEAEDRKRQLKEEKERKIKEKEELEKKLLKEKEEQELKQIEEYKKKVEEKKLKELELKKKRELEEKKLKTDYDLKQLEEKIKIEKDLIESRIKLEAEEKRKILNNKAILKQQQPINNNLSLLNQSPVQKQARLTNDAPTLLQQQLQNVTIGHPQHHLPHDIDILQLTSPPPASTSPIGLSNPLPNPGYLNPSLPINTLGLPQPPEFTEYVHQLSGHYGQQQLAYNQQAQGNFLPFNYVPVTNPNQSGFLRNNNINELLQVGTGVNNNNSVNNTFLQHQQLPQQYPVVSLESSPQIQQQQIRTFQQQQLHPLNSTTTSPTLQNQFSSRFVNEMGNGVGNANTAFFGQIQQQTPIPQQSVGVIGQNKKVGLKNKASFNGMKNVENESFFNSSTSMVNENNSNFCGSLALGGEVFNSNLPGKSSIWSFAPGDRAWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXS6</accession>
    <name>A0AAD5XXS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007947</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000082">
        <property type="protein sequence ID" value="KAJ3224762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="354" mass="41888" checksum="CF443B2386503A14" modified="2024-05-29" version="1">MKICDISLLNHKNPREFYLSTIRIKTTHHELHNITYNLNKDKLFEELPFDKEIQTSLDLDSDTLYYLMQESSIMKNFSNYEKDLYTLLYFFTDIVASTVDFTEISVRMNFKLWMKKVKGVTWEFKVSFQKFLSEVVSRTNIENEIDLESISRPPVSNYTVELINSNKLKVDKYEDAIIKGILKLSKFGTWIPKPKILKFLSENREKFKLLKNYRLIVYSKLKTLVKKKYIEKKSFANQHFFTISDELEKQICNIQDFEGIECCSDISDFVSNSGIIDEHEVPNQEFLTDFTIYNGLNLSKIRMTNYNCQSEYLDINFENNQYLKVVDGERIFKTFIGNEDNGIESDLIWGLYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY28</accession>
    <name>A0AAD5XY28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Magnesium-dependent phosphatase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">MDP1</name>
        <name evidence="1" type="ORF">HK099_007497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000073">
        <property type="protein sequence ID" value="KAJ3225024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY28"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010033">
        <property type="entry name" value="HAD_SF_ppase_IIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010036">
        <property type="entry name" value="MDP_1_eu_arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01681">
        <property type="entry name" value="HAD-SF-IIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01685">
        <property type="entry name" value="MDP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901:SF14">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17901">
        <property type="entry name" value="MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12689">
        <property type="entry name" value="Acid_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="133" mass="15082" checksum="1C24766D13C7138C" modified="2024-05-29" version="1" fragment="single">LPEMYQLWGGGGAPFEVIGDGTKQLADRRGEKVSLLGITDEILESLSKQKDIKIAYVSTCDEPEWANDCLRKFKTKSGIAFDKLVAEDHCLIYQQNKSHHFKKLKNLNPSIKFEEMMFFDNQMNNIEAVSPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY64</accession>
    <name>A0AAD5XY64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_004528</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000321">
        <property type="protein sequence ID" value="KAJ3219951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18597">
        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00829">
        <property type="entry name" value="SCP-x_thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055140">
        <property type="entry name" value="Thiolase_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22691">
        <property type="entry name" value="Thiolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="524"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="562"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="636"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="665"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="743"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="785"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1095"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1133"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1200"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1224"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1312"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="526"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="836"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1137"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1405"/>
            <end position="1639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3219951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1654" mass="185469" checksum="4C13E1BE3C03CCA8" modified="2024-05-29" version="1">MKNRVFIVGVGTTKFEKPLTKNWEYYEIGREAGEIALNDARLKFDEIKAAVCSYCYGEPTCGQRAVYELGMTGIPIFNCNNNCSSGSSALMLASSLIKSNEFDCVLALGFEKSGKSLEVKYTNLEFPGQKHFNRLTQIGAQKELVSKHLNYHSSEVLKMFSYSAGEFINRNYNATNNFDTISFKNHKHSKNNENALLQKEFTLEEIKNSPKIFQTVSALSSAPIADGGAAAILCSFRFMMEHGLQKNAVEILSQKMATDTIVTFTGDYSDVCGFYLAKKAANDVFKETNLKMRDVDVLESKTIVYLQFSPVYLLNFFSLSAIVHDAFSSMEVQLYAQLGLCKEEETNDFINSLKWVKNENGGEIGIFVNNKKWWCVNPSGGLESKGHPLGATGIAQCAELCLQLRNNANKRQVPGNPKIGLQHNYGLASACKIAMLKPKVKSNEIELQNFYSFLSFSWLSALIYKGFRNPLEYKDLFSLNRSLSAEVLNLEFNTLWKKERKQTNRKPSIHHVIYTFAYREFSGIYLMGLFADLSITFLPFILKYFLKYISISKEYSTSYHEGLIYIFSMLLLSLMNTLFLNLFLQRSVVVGMQVQQAVRSLIYQKSLVLSLSARQEFDAGRISTLIATDTTRIFTCLCYVTLLWAGPLQAILIFGFLVAEIGYSSLYGVILLILLSPLQGYFYKKLSAIRKIVAPITDTRMKLMNEVLLGIRLIKYFSWEDSFAKKLSDIRSRELKLTFRKSIIGAFSRTVVLVIPLFCSLISFVSYGLTNNSLNSSSIFPALSWFAQLQFPLSLVPMAFGFLAEYKIAVSRIDEFLNAQELQERVKIGYNKQYSIEMENCNFVWGSKKDSFRLKNINMKIPTGSLVAIVGKVGSGKSSLLNAILGEMKRELGSVSINGSLGYSPQQAWIQNTSLKQNILFGKPYNRHLYSLAVRNCSLDKDIALLSEGDETEIGEKGINLSGAHVGKNMFENCIVNGLQGKTRILVTHQLHLLSKVDIIIVMDAGEIVEQGPYQQLLHKKDGIFSSLASSYGGISTTTVKEKRFSNIKFLNESEEVNLNLNKSDDKKNLMSIEERIIGNVSSSVYLGYAKSSSVVLVCFFALALLIFNLAKLGTDYWLIIWSNNQIPHFSNFQYIAVFFAWGLLQVAFIGIAASKNLHDKAMARVLRAPISFFDTTPLGRIVNRFSKDIDGIDNTLSDGLASFLTTISVALSSVVLICYNLQHFFALIMLSLLFFYFILQKVFRANSRELQRLESISSSPLYSHFNDTVDGLSTIRAYHKESFAMEVCNERIDQVSTPFFLLYSCQRWFSIRMDILGALLVFSVGIFAVFERFEVSTAVVGLSVSYALQITGVLSAAVRSFAETESSMNAVERMQHYGNNIPEEAAPVIENSRPPKNWPSSGTIKFEDLDVSYSKDLPLVIKNINFTIKDKQQIGVVGRTGSGKSTMMNALFRIMEPSSGTIYVDGIDIRTIGLSDLRRGLAIIPQDPILFSGTFRSNLDPFGVHSDNDLWNALERANLKSKVMENKSGLDSIIQEGGENLSVGQRQLLCLGRAMLKKPRILVMDEATANVDFETDNIIQKCLREDFKQSTILTIAHRLNTIIDYDLVLVLERGEIAELGSPRELLHIENGKFLALVDETGLTNAKLLKSLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYG2</accession>
    <name>A0AAD5XYG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000038">
        <property type="protein sequence ID" value="KAJ3226357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYG2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052523">
        <property type="entry name" value="Trichothecene_AcTrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791">
        <property type="entry name" value="GNAT FAMILY ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42791:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="8046" checksum="99711D22F0E75765" modified="2024-05-29" version="1">MRSHQGKGHLKEVFREPLKLIDSEKAYSYLEATSEENVRIYQKYGYEVVDTFTLGICTKVWCMLRKPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ51</accession>
    <name>A0AAD5XZ51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytanoyl-CoA dioxygenase, peroxisomal</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ51"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048244">
        <property type="term" value="F:phytanoyl-CoA dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001561">
        <property type="term" value="P:fatty acid alpha-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047128">
        <property type="entry name" value="PhyH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21308">
        <property type="entry name" value="PHYTANOYL-COA ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21308:SF1">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="35929" checksum="CDE71DA188836F02" modified="2024-05-29" version="1">MSSANRRIDSTLNHLNNFRYTLPESSDLLSLEQRQQYEKDGFIIVKGLISQSEMDSYRKRFIDICDGKVIPEKTMLVMKDLATRKNKDIKGELKLAKLQDFQDDPVLFEYCKHPKLLEYVKCFTGPNVKSMHTMFINKPPNVGVSSTHPMHQDLHYFPFRPADRIVCAWTAIDKTFIENGCLFVVPGSHRADELLSHGYHEWEGKVNPMYHELKGAAKGNDKKFFAEMDAGDTIFFHPLLHHGSGPNTTKGFRKCISTHFASANCHYIDVKGTIQENIAKEVEEIAKRRFGDAVPFDFIWKVRSRLVAGEDGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ84</accession>
    <name>A0AAD5XZ84_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006178</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000518">
        <property type="protein sequence ID" value="KAJ3215820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ84"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR XBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="3">
        <location>
            <begin position="154"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="29735" checksum="2291F2ADAD1647E2" modified="2024-05-29" version="1">MLTHTTEEIEDAEVLDNVLLLPLPKKVKTILYPTALFPVFSPVEDGRESLQQQHQNHQQEYQKQFKMNGSTTLISQPFQPNNFLNTIRKNHTANNGSNSYEYNNIPFNVMHPQSPTIIQSNLSTNVSTSSDQHYNNQKKKIPMKLPTPYNNEGIFTAVYASVPVYEFHIGEYTIMKRISDDWINATHILKTAGLEKSQRTKLLDSFVKDKKFEKIQGGFGKFQGTWCPNNVAIELSQIYNVDHLLKPILWVKKPHHPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZH6</accession>
    <name>A0AAD5XZH6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004626</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000332">
        <property type="protein sequence ID" value="KAJ3219645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZH6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="440"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="502" mass="59716" checksum="971DA58B6441087D" modified="2024-05-29" version="1" fragment="single">MTSSKSWNSSEEGIENEEPSWITKKLQADLDDQSTTDGDIQANLNLVKNLINKHKSVENYEMEIYNYNSTEYLSEKEKFDDEIFTSNYLNPDIVSTSSLKELDQEQVNLTLKLITEKTALNENLKQTNFNFFKYLKKILIYFKQELKKKKEVRELVDILEELGDVMQFRVHFGNEYDLFLKEFFNSNSNNFRDESKSLNNERESDMRDLKEKLLVLRDSNSRQREELEDCNKEKLETLVHIKNLEDTLIQTKKKIEDLKNNLEFYQNENNNLKISKKNLSEKFELCSISEKTFRENFLEQKTIVKDFSLKTFHLENLLQQHKDALEEARIYHENYKECQKMVNISNNLNISHLKHVVQKSFGNEDYNSEVEVVEEIIGSEKSDDIVEIQALKAELKMVRDRYDVDTMVLQKKLTLVESESENFRLIMEEKLKNFKTEEEWNTLLSDLKTLEKEMEKKESDILIKEKLIKEFKESYFKMSAELNEKKEDCFKLNLSLEKSREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZI6</accession>
    <name>A0AAD5XZI6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000328">
        <property type="protein sequence ID" value="KAJ3219734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZI6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="952" mass="107609" checksum="7EA61284145C5C2D" modified="2024-05-29" version="1">MRILLKGRYARNSVRPLPSTSSTKKSGIIRKRVYNTSIESNTLPNDVSSSLIANSSSLVLSNECSKCIVINDNSMKMHLNISMNCKYCGKDIGCIYNDLEYNELIVNNLEIVIDVGSLDSKYLEKLKCINKHIVRSLNIQSLFIRLRSDHESYKLTEAYLPRIQSLLLVFGDGCLYTTTLDISLRFSTALVKSIVIWSICKRTTDRELIASRLGADEPQVVSPCSCKRFKNLDLNNIRTLVNGLAKSQNKERGSTLHSTNANTRNSDTMGANLKSRIHSSSRIKPDTNLWNIEGEHIVSIEQEYEIRVDHANLSNIEAIDLMSPKLIVFTEEGFASLIGWKGECLSVKCRWRSNSQYPTIKIPGNKVAIAPGCKYTQSTEVHITTQMYYNLMSQNHTSFYRCKIMEKSYIEGPWEIRFRVYEPSIKQSIEIEYTISKQKPSTENIVQALVDFMSRFGHYSLRNYINKDFIFALVMNKRAVYDTKLFSRGECIFMVKVDGQSVWLIDGGYLWYICKTNLELDVISFFPKNDLQEFNTRPDVTHCELLINGHLIYIDTVARSECTLGKQRPFVDPKQMLKTHRSIPPVSIRIIYDTPENAEAELCITNLPCDGIVGVYLATSMTVRKKAPTVDLLAKGDKLLCESKAYNGRAVMQKEEYMVDGYVYECTLDVTDCNVPKIIKSLFRPDKLFPNSYTVYSSVILNASGIKGVHSVIRKNITTFCFGIREKLYSIAKNARTNGKLIIDVGTGRCQSATFLLDKNITWLLCDPKLSGVHTLRRPIEHNISSEDSDTVISILRSLNRGKIEIATIKEPLSNLLKVPGVIEFITQYSIPIVCSFSASHVVSEINELNESGALVFGCCYSYDKANKDGVVIDKYGISMLIHSQDPYSGTFVFGTDNEVKESVVGRSSFPDYEIVEALEFLNDSDIVVEEVKDILSNIIVFSSHKDYINSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZL3</accession>
    <name>A0AAD5XZL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000151">
        <property type="protein sequence ID" value="KAJ3222958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="37566" checksum="B54AAF99096C0D30" modified="2024-05-29" version="1">MISLLLPEMIDSYQFSPYHQQLKREQDYRRYRQQQEEEKKRALQQYLYNLNEMNNFDPYYGSFARRRPVHKRNHNWEAQEELKKCKAAKKIQHAFRDYNKKKPSLVQLKKVENDLESLLATRDSIILNFKNLKKEDVIDSNKKKIKFNSKTSPFLSFEDSLFKLVMSLDEINSFNSPFIKLTRKDLINKINANLNIVDKIKNDILQEEENKVDSDIELESTVGSLISNEDNTSTTNPSDCSASEMDLAESWDMMETDCNEKTENSAENISIVNEKSSNNAVQDQEMSTICCDEDFNDNFVPKLIDNNVVLDLNSFRKIPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZS0</accession>
    <name>A0AAD5XZS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SET and MYND domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SMYD4</name>
        <name evidence="2" type="ORF">HK099_004278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZS0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="3"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="357" mass="40695" checksum="1D596B8DF8F5D1D7" modified="2024-05-29" version="1">MIEKVEVIQTTLGRSCIAKCDIPAGSILFSEDSLLSQLEFNLLGELCSYCFATLMNVTRSCDNCLAKFCSLTCYQKGYQLHTSICKIPSTRIIPQQYLAVKLIHGSKIIEKIDTLANPTPLFPSFNLTSNQFILTLDDNINIIEKYSEEIPKIKIGVELIAKKLKYSISQEQDLLKYTLKLKNNAFMVNGVKLDQLSGNSENISIGTVLYTYGSFFQHSCDPNVFYLFDKMKPTRITFRTLKKVLKGEELNISYGPLKFQDCTSSRQKETLEKWGFCCKCKACNLNDDEFALKYNGYLCPQCCKSPDIKKEISQCDADFHQKFFKNLDAEINNFFYNCNSMNVGDCIKFLNFVRGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y078</accession>
    <name>A0AAD5Y078_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008628</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000097">
        <property type="protein sequence ID" value="KAJ3224305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053033">
        <property type="entry name" value="Androglobin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054093">
        <property type="entry name" value="Androglobin_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054094">
        <property type="entry name" value="Androglobin_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46298">
        <property type="entry name" value="ANDROGLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46298:SF1">
        <property type="entry name" value="ANDROGLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22068">
        <property type="entry name" value="Androglobin_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22069">
        <property type="entry name" value="Androglobin_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="3">
        <location>
            <begin position="284"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1154"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1325"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1154"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1175"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1339"/>
            <end position="1348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1348" mass="151543" checksum="0C3A50D72216D5BC" modified="2024-05-29" version="1">MKKAGGTSKDRLAKSGNPKKRTPSNNPVNNSQIGGPGGLNQQNIPTQIGIDELPEQQILIFPEWVEAEIIGEKWNTKHTFDDPEGLIILPKSLRHSVDSWKRPVELTEQVPVGIVNQNSLESIFCQNIPVNTQPNTIPNTAPLSRQGVSDTPGILETPEIFDLGTEPVINVTTEPVITPIKETKEETGQIDAETSVAQNKIESEKNSITASDHVEEQPGSSEQLDPLQNASQLFQHNQHLLVSDLMKNILITIHFLYEHAAKQTRPHTQSSDESLPWDYIFPKSKDGLPSYNVSGKYVVKLHWLGCWRKITVDDKIPVDIEGRPLLVSSPFGEIWPLILSKALLKVASTSFKEQDGCCEYGDFDVINTIRGWLPEKLSVNQHKVNNGLWAIVNGLFLKPSNGSNTAGSNFGNSTAVANQHGSISNLIGNSSASVSQTKSGNTSSTIILNKTEREKSTVPPTAQRPSSIISTSTTATPAASYIFALKDGEENSEKIELNSMQFLYRITDAKENIVLTNQCGNAINFNSNGSIENVGRPSVDEWDYTQVVQRFLKIKSFFACGKQKKTNLVASKLNKEGGLSRVCSGDNLVKEDENEVWISFTEFCRTFRFVTVYHNPTSFKMVKHIQHIVDPLKPSDQLIIIPVLCKWSKNFKLKIHFFKKKNVDLPESVKESTVMISLHTYGRCTPDVSNVSSVIVEKWNWDNGIRSTKENNPLIKLTTNSCILSVLKINRGKHAYKFQIDCPSSYQLSIWSKEEFLLEDTPKYLETIGIQVKDIDEISPQQPPNSWCLFVPELIEVYTCLRLFNNDSEKEGLSVEYPLSFFNLKPQLLLPNKNGYTLIADCKMPIQKPQNKWKLRFYSDPFHSPEKLFEGISLKPIVQDFEDLIVPNKHNILFRYIIKIKDGPENRVSMQLSFNLPFVSLNLQLFDHEEEIFSISGKGIVSMHAVTLYANFPEGDGILVPPPQLVENKKGTKDGKDAPKVDLSVKEAVKPPVRSMEPIEWSKFLTTKGNQANDERPVSRGIKTTGSGKKKKSTQPAAQPDPPVITGVASSEPNWKLRFVSTDSVSLIVTKDTEKEDRYRALKDSWELSQPGRALKAKESREQYIKQVEQGLTKPLVFGYTAAKEVCKPWTIVNSKPDKIVELPAYTSTANIQTYSRPTSGKQNKSLSRRGSSMNAESNLNNLPNNALKEESQVNNLVEEAEELMNSLSQQPVLLVNWPTPTSPARVPSAVEVEERVTKRESLFQEYTDFKESVRKERQKDKERRSLIKLHQSLVFEMRQKELETEVKTDIERRENYKANVIKQLEEAVAKKYQLALEQARLAELEAINNPDENEGKDNKKKKAGKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y175</accession>
    <name>A0AAD5Y175_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001515</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000143">
        <property type="protein sequence ID" value="KAJ3223114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y175"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005469">
        <property type="term" value="F:succinate:fumarate antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF2">
        <property type="entry name" value="SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="8"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="108"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="215"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="324" mass="35651" checksum="40F35B85EF3FEE25" modified="2024-05-29" version="1">MNSQKKERNLGIHLVSGGIAGCVEALTCHPLDTIKVRLQLRGERAQAGLKVNNVGFIGTGIGIVKREGFPSLYKGLGAVITGIVPKMAIRFSSFEYFKGILNTTNDKPSALVNFNAGLLAGTTEAVMVVTPMDVIKIRLQAQKHSMSDPLDIPKYRNAMHCGYLLIKEEGISSLYKGVALTALRQATNQAANFTAFQFMKAKLTEYQQLTDNQVLPSYQVMVAGFISGACGPLFNAPIDTVKTRIQKNPSTEKGWVRFTKISKSILVNEGWRAFYKGLTPRVLRVAPGQSVVFVVYEKVSDFITKTVQTIQYEHTPEYPGVKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1Q8</accession>
    <name>A0AAD5Y1Q8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Origin recognition complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ORC4</name>
        <name evidence="3" type="ORF">HK099_000220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000104">
        <property type="protein sequence ID" value="KAJ3224109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1Q8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016527">
        <property type="entry name" value="ORC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="53"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00019083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="265" mass="30459" checksum="2ADD881218AF802E" modified="2024-05-29" version="1">MKTNSKVLNVSQAEVEKVILSLTSKLASFENIPQTKRNLVLRKSLLTYLEKDESNSVLLMGQSGTGKTTILNNTLFELETIKKVNFPTIIKLSGILQQTDKLALKEVARQLGLESMVEKANLRSFSECFNFILATLTEIEQQDSRRKNVKKAIIKPLVFILEEFELFALQPKQLLLYNLLDAVQSALRPIIVIGLTNRIDAIDLLEKRVKSRFSNRVIHFQQPDSVSSFIEILKFYLSIESSNERQIEKQYLEHFNNEVEKQRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1R2</accession>
    <name>A0AAD5Y1R2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Alkaline phosphatase</fullName>
            <ecNumber evidence="2 11">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_001716</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="JADGJW010000151">
        <property type="protein sequence ID" value="KAJ3222960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1R2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF5">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042291565" description="Alkaline phosphatase" evidence="13">
        <location>
            <begin position="18"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="47"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="67"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3222960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="596" mass="64525" checksum="74F6D6FE37F175B2" modified="2024-05-29" version="1">MLFKKIASLAILNLAISVPTKQKCKHHNHHHSINDADTKDYVFAEDGGYQHSQHGNSLPVTCTGAPNSGNGNNGSNNGSNNNGSNNGSNNGSNNGSNNGSNNGSNNGSNNNQGGGSDNNEHTKFKNVIFMVSDGFGPASETFARNYHNYVNGYPKTQELPLDTILIGSSRTNSDDSYVTDSASGATAFSCGFKTYNAAIAVKSDLSPCGTVLESAKLNGYLTGLVATSRITHATPAAWSAHVSERDDENRIAQHQIGNYTLGRVTDLMIGGGSRHFQHKSVKGSKRTDDRDLLAEAAAIGWDVGTDKASFDALTSDSKLPLMRLITQSHLSYMIDRDPTKEPTLKEMSDKALNILKSSTEKEDAKGFFLMIEGSRIDHAAHSNDARTHFEEILAYQETIELAKKFVDENPGTILISVSDHETGGLSVALQEGIEYPVYEWLPEALTKQKASTEVVSSVFEKKNKELSGDAKYAYFKEEIKSIFNINPTDEEIAFISAAPDAQTIDNFLGTAVSKRAKLGWSTHGHSAVDVNLYAYGAGTNALVGSNENVELGTFVETYLNLDLEAVTKILVENVASLEIQPLITKRSVSHHHHEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1W6</accession>
    <name>A0AAD5Y1W6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 58 central coiled coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001296</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000135">
        <property type="protein sequence ID" value="KAJ3223322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1W6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049270">
        <property type="entry name" value="CFAP58_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083:SF0">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21771">
        <property type="entry name" value="CFAP58_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cilia- and flagella-associated protein 58 central coiled coil" evidence="4">
        <location>
            <begin position="370"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="841"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="147"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="640"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="843"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="892"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="983" mass="114554" checksum="160B2776554DDB90" modified="2024-05-29" version="1">MEEISIIANKTLGITNPDFNPTADLLQFKIEFENNERASEEIHLEFEQVLKSLADEDQMSKFTIEYQKMYRALNNSMGNIEKLYQQHIILEKEYIQNIDSNHETLKTSLNDQLSISSLKSTITKVQENLQASALREESGVGLSTVQERTLQELHQAKEQTTKELEQELDKIVLLRTKIQDVTEQIKQTDETKRRFEHEIYELKEKNTIKKGDIEGELRNKDRLEKELREIRSIVGAKSQEVRGKQDVVNRCADEISMIDNHIKSQRQMLERLQKDQDNLFQRSIKLKADCGEQIAISSELAEENAQLQKDSKTKTQELAKLHNEVKKLNKIKDTLMKKNKLLEEQKSNLDSKRKECKTENDCYVTEIEKIRRQIEIYKKTMEDFSREKGIIDSNFEKALTSTHSNNMLLVPYKQTRENLELEIARFEREIHIDNKVLKKVNSEKDLYIKEALSLQQKCVEGLQIVKKKELAIYDYKKQMVQADTKLKHQQALYEAVQSDRNLHAKHLVEAQSDIGEMKRKLKIMNYQINGYKEDINGKEEALNRESTENTKLLKDIDLISDETKNLKNQNEIAQAYIKTQLAEELKLNQFVKEAELERSRQENALQALISERDNLCSQLIKQDDQLTKVYGKIKSNTTSLMSSEKQYEKKLAEIRELKNQIRNLNKSKFELKMETSQLTEMNLKLCRMENDVVFEKTRVKALEQELVHPINVHRWRKLEGSNPKAFEMIQLVQALQKKLIEKTNLDNEKVKLIQQNEEIYLNCKTLLSNQVGPEAFEQVREFEKLLKDKQLQLKHMGTELNMYQAQGKEYKHAIEVLNKEIDEQYIAEHYRNKNRGYYDDMTSSSVASSPSPLPILPSINSKKPFPDEFDPPPEDLEMHASEESNDNNFNTEHNEDNNNQNKHDTVNINEDEQMAPNSDQGTTALDEVLKPNAVEDQLEDVSRETTEMQGEEAYAELVDKKEMQSNNSQQDETVAVIKIANLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1X0</accession>
    <name>A0AAD5Y1X0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000134">
        <property type="protein sequence ID" value="KAJ3223350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1X0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="115" mass="13150" checksum="CCF549DC846E355F" modified="2024-05-29" version="1" fragment="single">ELAEKAKKENYLLKSSIIQFKQDFHKNQNAAGSSSLNSKGRYSSALNTSRGDCFPAEKVSASENLKIMRLEREIENLKKKNTNLEEKWNNLKEVAKKRLKEGEKLSSNSNNTHHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y290</accession>
    <name>A0AAD5Y290_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="5">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PDA1_1</name>
        <name evidence="7" type="ORF">HK099_007334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000070">
        <property type="protein sequence ID" value="KAJ3225129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y290"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000013">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050642">
        <property type="entry name" value="PDH_E1_Alpha_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF60">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5 7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="6">
        <location>
            <begin position="69"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="393" mass="43792" checksum="1889F9ED97134871" modified="2024-05-29" version="1">MFNFFRSTKNVVKATLNSPIIHPQQQVALSRRNSTFTFKLPESSYEVHNCEKPKFEVTSNKEELLALYRTMMAIRRLETACDQLYKAKLIRGFCHLSTGQEALAAGMEAAIVKDDAIITAYRCHGFTYTRGASAKSIIAELMGRYDGSSKGKGGSMHLFAHEFYGGNGIVGAQVPLGAGIAFTQKYLEKKNMTFALYGDGAANQGQIFEAYNMAKLWDLPCAFVCENNKYAMGTSINRGAASTKFFTRGDYIPGLRVNGMDVLAVKNACEYAREWCTSGKGPLVIEMATYRYGGHSMSDPGTTYRTREEIQHMRSTSDPLTGFKKRLIEQSCCTEDELKAIDKEVRAEMDQAVADSKNSPEPPISELFKDIYVEGTEPKSLRGCDPHDIHYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2M2</accession>
    <name>A0AAD5Y2M2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000052">
        <property type="protein sequence ID" value="KAJ3225804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2M2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="110"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="534" mass="58786" checksum="C9B5224DCF71793D" modified="2024-05-29" version="1">MSKNEYHLSSFSAPTVTGSLLKIFHFILKYFGWMGITYKLFTDSNLHLLRKHPIFLTPTLMPIKDQKDPENTKAPDTSILKNNEYREGYLKKVFTPTDVANTLIKNIEHSQSTEVQLGAIIKYDKNDILKQAHASTERYRNNKSLGPLDGVPVAVKDEADMLPYETSLGTSFVNIKPDKDAFSVGKLRSAGAILFAKANMHENPYSPNHVVGGSSGGSACLVSSKLCPIAVGADGGGSIRIPSSFCGVYGLKPTTSRVSTNGSFPLALTVGVVGPIADTASNLALAYSIMAGPNPEDPYSLFQNRVSIKSFNNINDLSDLKIGIYRPYFSHAAKDIVESCYDFLRKLEKCGAKIIDMEIPHLEKLRVAHSNAITSEMLSGFSAFDMNKFSLPTQCTLHVVKANLGARDYIDTLKYKTLGIKVFEDIFKEFDLIVSPSTGITAPEIHSNSKSVGISDLTNSGATMRFIFLSNLLGFPSVTVPIGFDKKGLPVGFQFQAKWYNEDLLLRMANFSENINRESLQQVTAKINFDNLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y473</accession>
    <name>A0AAD5Y473_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y473"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="749" mass="85090" checksum="733BB8D6DFAD9C17" modified="2024-05-29" version="1">MTLFLISGFVTVVLMAVNLYFKRAVIDAVMWWFAGLMAASSGATFFHKFYFASTIEFSSQIFAFGTVACLKNFICFNFYVVHRCLFYHDVRIAEKEKKNINKTINGLTCNDFNDDFWNFSVSDRYQTLSFLISATLKLVGIIMILVQVAIAQHPNSFDNVFLIACLLSLSFELGSYSRWFSLKMTGLIFSIGSISLIMKLFVDKIALLPLYFENRSVGYSNILTFVVGISFYLAGSFLMLFRILTTKNSIRFYSKLKCRRIILIYLFIFTIGWVGTISGVAISSEISALKIVSLGAGLIFILTVILTMLQKLNLFKYLATFFGVLNLVLISLPIIQLLEDLNLSRTKVSEILYFCGSVIVHLISSFFLITILVENFKSNLISENNEKLDEVVKDEEEDQEKKGPPKKHIEFKSKITSFFRRMFSKKKEDLKKSDNEEEMDIEEVAAKMDHQNQQIEIDIENEEIGVNNKNSFSAEDVQVPLIPVDDNNFENAAPFEGNQLSRKNSNELRFSVNNTRGLDMQNTMDAKETADDSDGRILPTLLKKDSEENDNISGKSGFFQRASTLGRSRVTTNEEKKDPSQVSETNSIISGFFKRVSSLGRSRSPTIDSKSKITEDIIKQAKNNNLQEILEEGSVEEENCDFERNSINQVLPLKDLKQKGIFLESAVSLSGFQIPDDWNDGDFAEENAGFTSPKKRLSANNEKKNRPLTKSSSLRFPEETFPLRNSSINTSKSKWMKNKQSRMQVDNFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TST4</accession>
    <name>A0AAD5TST4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-dependent DNA helicase sgs1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SGS1_2</name>
        <name evidence="1" type="ORF">HK099_003377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002215">
        <property type="protein sequence ID" value="KAJ3198991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TST4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="301" mass="34539" checksum="C384DADAA3C62A7C" modified="2024-05-29" version="1" fragment="single">MFIKGTAAITTTYSKNNSINDRATLNCRFLDSQTSLYLFQYLSLIRPTLLLLASIKSSNQTQINNLNSYLFVHPSGERFNSNNIKMKYCEIFKKFMHVYIDFSTNRQLMIYFAKVNNIRLWLGSKEGNTADEVNEDGGFDIQANHSAKTANINYGRGRADPFINIVGIDDYTRGLEFSTKWQELLLVKTSTIPNILHSNTVHNSIETISSSNVDNSTGTTPNIPTQSIVNIYSYNYFSNSQYIPKKRKLNEIFADNNESQLSIFDVHNQTEEKQNSRIKNHLQLHGFEDWRSAEQLTLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT86</accession>
    <name>A0AAD5TT86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alginate lyase 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001719">
        <property type="protein sequence ID" value="KAJ3201483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT86"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase 2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3201483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="19992" checksum="BA17E3F9202C9B44" modified="2024-05-29" version="1" fragment="single">VTQIPNNQDGGVITAQIHNGNVPVLIVRLNVNVLSVFFSNFPGQTTVLDGNYQLGTKFSIELQVVDGKMYVLRDGGIISDCGGVPITDAQAFFKTGSYNQNTLSSLNPATASADVEIYTALVQHDLNLHTPPQKCTFRFTTGLIAGIVCGCIALVVIIFITCICCNKKRQAEAIPKVYGGFQGNEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUS2</accession>
    <name>A0AAD5TUS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003118</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002090">
        <property type="protein sequence ID" value="KAJ3199539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUS2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000026">
        <property type="entry name" value="Calcium/calmodulin-dependent protein kinase type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3199539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="27182" checksum="27C14B44010E3CF2" modified="2024-05-29" version="1" fragment="single">QSLRNEIEVLKRINHKNIIGLKDFFETESRLYLVCDLAEGGELFEALIDKGFFNEKVAAQLVKQLLEAILYLHSKDIVHRDLKPENLLFDSKSEDANLMITDFGLSKYIEENDILKTACGTPGYVAPEVLMKTGYGKPVDMWSMGVITYVMLCGYMPFYGNDAAEIFKKIIKNEKEFEKEDWSEISSSARDFVEKLLVTDPKERMTCAEALNHPWLSNPGETDLMKSAQKYFNAKKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVS6</accession>
    <name>A0AAD5TVS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001009">
        <property type="protein sequence ID" value="KAJ3208155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3208155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="437" mass="50670" checksum="495193C89FC7D713" modified="2024-05-29" version="1">MVYDPAVQRLQRLHPEYFHFKSLNINLLKEETQISKKKKFKLITMTLIETNKNKKLKNDEIVNNGELQISKNPSGIVDSKKEENNECNSKEDIINLKHVMKRMKPKTGNDNLSLENKNLLIQKRLGILQNELDGLNQDIFENNLFIQVLSERKICLEQKDLKIKEFLREYLVETLKKVYQTELVEEPAQHAAFLPSIEINNDKKIEVALNLILDKLKVFAVDLKFEEEINENLNELELKKNSPELKNKKENEKRLPTNEMKLSTTMPDINRCTTVTVNSEKFKPFQKKLNLDCKLLGFELFGNCKLESKLAGSFIKIDGDESFYSSCVTIAQNKKRLTLENFASSRLPLKKQELLLPSIFSEIKMSVGRTLTKKKEAPLTSFPSCTGYDETPKLSHLKFNDEREFKKKVSKKTLKVIKDQKLREQKNYNLKAVLSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWC6</accession>
    <name>A0AAD5TWC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BRISC and BRCA1-A complex member 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">BRCA1-A complex subunit BRE</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">BRCA1/BRCA2-containing complex subunit 45</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_001906</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the BABAM2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001597">
        <property type="protein sequence ID" value="KAJ3202261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWC6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070552">
        <property type="term" value="C:BRISC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010358">
        <property type="entry name" value="BRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15189">
        <property type="entry name" value="BRISC AND BRCA1-A COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15189:SF7">
        <property type="entry name" value="BRISC AND BRCA1-A COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06113">
        <property type="entry name" value="BRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3202261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="30601" checksum="047295378EDBF61C" modified="2024-05-29" version="1" fragment="single">VHVNFDSDDPEYPPDICVEKDLKYLNILNLPSLLYWDSNNTNALSKVLFEIKDIFMQEQMKFISSLNISSLQFDLSMISHRQNVEIAFQKPNLILIKIPINITLESGQKMDTNIRELISHEIGLSLLVKYIFAENYITNIHVDVLDLDKEISEVFKPPPYKNEYNLLDYLDCFEKELKNSMIKKFNLVNLRKSFIKLLKNQFDTSKVVKLMLTEADLDNFNFVSFTLKYLKVDLSLEENFNLPEWKKEDLYIFNSKIVFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWD2</accession>
    <name>A0AAD5TWD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000803">
        <property type="protein sequence ID" value="KAJ3211965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWD2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042846">
        <property type="entry name" value="BTBD19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46965">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46965:SF1">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="20"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="2">
        <location>
            <begin position="217"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3211965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="48680" checksum="2D47AC486E2E5F35" modified="2024-05-29" version="1">MIIFYVSLSNDLKKLLETKADITFAVGPNRILVHGVKNVLSVRSKVFDEIFKISKPNQIISLPDVEYIESFRFLIKGLVTGFIEKSFFLDQKSVLELMKLSMEFCAQNLQEISEKYFEANLKLNNIFIFLEDCINLKNANITASLVDFIQYNPEILYSRELFELSIKGLNFIFNAAKPAVENSLLLKTLIIWKSHNVDVADSDLKLILEIINFDEMKDSEIFELEKLGEVGKQLKNKIFFFRDSHQSDTVSKKRKIELPEIIFESPYDSSKIKPNLGGQVQTILSRQSFSDGINSWEIRIENFNQCFFIQMGVATENIIRKERYAGHQLNRLAWMLGSTGKLYHGKKAAVGDAKIVLETGTNTLKFTLDLSTAERMLYVEKKINGRLFSEKTELFRILDTSPLFPAISFVDNEVLEFSIKRVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWF5</accession>
    <name>A0AAD5TWF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000735">
        <property type="protein sequence ID" value="KAJ3213205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWF5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="11862" checksum="94F380D5CE9A956E" modified="2024-05-29" version="1">MSHYDSPVPKVISDNPKMMKFRRRVLNSRKMNETPTYRKVKVGGYFLMAFSVVYTVLFADWGDREHCYSGVRRYYYKKRREFFSLSENDKQGTISELIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWI2</accession>
    <name>A0AAD5TWI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007461</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <location evidence="2">Coated pit</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000723">
        <property type="protein sequence ID" value="KAJ3213315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWI2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09251">
        <property type="entry name" value="AP-2_Mu2_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14836">
        <property type="entry name" value="AP2_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043532">
        <property type="entry name" value="AP2_Mu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043512">
        <property type="entry name" value="Mu2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="9">
        <location>
            <begin position="157"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3213315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="408" mass="46301" checksum="8D505746BBD6876D" modified="2024-05-29" version="1" fragment="single">EVLISRLYRVDIKRSISDVFRIQVISNTDVRSPIITLGSTSFFHIKHENLYLVAVSKLNTNAALIFEFLYKVASLGKSYFGKFDEDSVKSNFTLIYELSDEICDFGYPQNTEPESLKLYITTEGVKKEKSPKNDAAKIAIQATGSVSWRRPDIKYKKNEAFVDVVESCNLLLSVQGNILRADVSAQVLMRCYLSGMPECKFGLNDKLQMNDDENRGTVELDDCQFHQCVRLENFDSERIITFIPPDGEFELMKYRSSVNVQLPFKVMAVVSEGETLCDYKIIVKSQFPAKFYAQNIILNIPTPTNASNAKLTVTGGKAKYVGGDNSIVWKIPRMHGQSELLLSGDVDLSPMTVKKAWSRPPITMNFSVLMWCSSGLVVKFLKIYEKSNYPNVKWVRYMTKAGSYQIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWJ4</accession>
    <name>A0AAD5TWJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NHP2</name>
        <name evidence="9" type="ORF">HK099_007799</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000793">
        <property type="protein sequence ID" value="KAJ3212148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWJ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="8">
        <location>
            <begin position="50"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3212148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="163" mass="18368" checksum="D0BEAEAE52A1FB08" modified="2024-05-29" version="1">MGKTTKQEKKEIKEKIKEENGEVEEITYEKRLNACNEISLPMASKKLTKKVLKTIKKASKQKQIKRGVKEVVKGLRKGSKGVVFIAGDINPIDVITHVPVLCEESDVPYVYVPSKEDLGLAGSTKRPTSVIMVVEKKDVDYKESYDEIMKEVEELNKTLITTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWR7</accession>
    <name>A0AAD5TWR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007616</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000753">
        <property type="protein sequence ID" value="KAJ3213042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWR7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="78"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3213042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="240" mass="26978" checksum="52F3C8353193F569" modified="2024-05-29" version="1">MTVYLQISVGCQQDYKKKLSQYELGVNYFNTKRNQFGLNNKIINELTTEEQEFVIENYNNEHNNCNIILQKPESLVKGTFKFKLFENECPKTCLNFKSLATGESGVGKVSKKPLHYLNVPIHRIVKNFIAQGGDITRMDGSGGDSIYNGKFNDEKQGLKIKFKKGSIGMANKSKNSNTSQFFVVLTDEDAELKKLNGKYVCFGEVTNEEGLNLLDFLNTLGTDDGDVLNQQIIISDCGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWZ5</accession>
    <name>A0AAD5TWZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001034">
        <property type="protein sequence ID" value="KAJ3207765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWZ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="242" mass="27736" checksum="C1BE1F8D1DDA3957" modified="2024-05-29" version="1">MNIDSISCNSQNLTSAISQSHSKINTVEDLLKCVDNEVSFACNLLEELQSNCSISETCSDSSPRSSTSSNRTLHSYPPPTSDKKFETGQYIFEKHKPPSVDTWIKSSSHRVNITPLTEESFFSNILQDKPIDFISNYLPLLKKNSVQKFVFLDPNIETSHLNRPTPNNPMYKKNDNNKFNIHGENNFNNFASFFSESYLQGELIALFGSRRNQCHDKKSNLEQSNFRKRTRKPKELIELEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXH6</accession>
    <name>A0AAD5TXH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ER lumen protein-retaining receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ERD2_2</name>
        <name evidence="13" type="ORF">HK099_006573</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ERD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000578">
        <property type="protein sequence ID" value="KAJ3214994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXH6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046923">
        <property type="term" value="F:ER retention sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000133">
        <property type="entry name" value="ER_ret_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10585">
        <property type="entry name" value="ER LUMEN PROTEIN RETAINING RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00810">
        <property type="entry name" value="ER_lumen_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00660">
        <property type="entry name" value="ERLUMENR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00951">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00952">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042077187" description="ER lumen protein-retaining receptor" evidence="12">
        <location>
            <begin position="19"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3214994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="202" mass="23467" checksum="6C73B945D4EE8CBA" modified="2024-05-29" version="1">MHLVSIIILLLKIKKTRSAAGISFKSQALYTIVFVTRYLDLFTKFVSLYNTVMKAFFIGSSIYILYLMKVQFKATWDPKLDTLRYEYLLIPCAILSLIINQSFTFVEILWAFSIYLEAVAILPQLFQLTRTGEAENITIHYLGALGMYRALYIPNWIYRYYAEDHLDWIAVVSGVVQTALYSDFLYIYVTRVLKGKSFRLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXQ5</accession>
    <name>A0AAD5TXQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000976">
        <property type="protein sequence ID" value="KAJ3208810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXQ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="178" mass="18691" checksum="47A0EA0234E888CF" modified="2024-05-29" version="1">MFNPVLDSKVGNTRGRQSVQCASSEIAIANPQQNDHDAQRQQREQEKESRRASKSSERAQKEATKTQSDLAESAADSSTSAFASATKSAEESAATLTSIAQSTESVKTEIQETLSDLSSSGSTILTGTANGGTTVTETKPLPTNTNPPPAAAASAGLKMIGSFNTLIVTSIVFLYMLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY84</accession>
    <name>A0AAD5TY84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000852">
        <property type="protein sequence ID" value="KAJ3211154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY84"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="122" mass="13520" checksum="0F615755BDE53AE0" modified="2024-05-29" version="1">MDFLLNSVRATIWYTRTSPVFEGSMQDKYIQATNAWRAIKGLNPLVYDPDLNSTSRENNRVSSELNDMGHHVTGGPGTVKILAILVTLQKEMLICGTNIMNPDYTRIGGDENGAYGICTYGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYA6</accession>
    <name>A0AAD5TYA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein memo1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MEMO1</name>
        <name evidence="2" type="ORF">HK099_005794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000469">
        <property type="protein sequence ID" value="KAJ3216601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYA6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="243" mass="27801" checksum="4C4F39A6CD22CEC3" modified="2024-05-29" version="1" fragment="single">MLKRKSSHAGSWYSDDPKLLQSQLTSLIQKNTTTTQLDSSSSSIKALIVPHAGYSYSANTASFSYSKLNQNTFIKTIFILGPSHHYYLQGCALTQCSEYETPLGNLTVDTDLIKELFETGQFEYMTLDTDENEHSIEMQLPFISFMLKKNLNFKIVPILVGNLTSKNTNILANIFSKYMVDTESMFLISSDFCHWGSRFRYTYGIDDELPIYESIENLDRKAMELIESLCPEKFNSYLKKTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYA8</accession>
    <name>A0AAD5TYA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000505">
        <property type="protein sequence ID" value="KAJ3215995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYA8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042135161" evidence="2">
        <location>
            <begin position="19"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="241" mass="27120" checksum="598E01E6BF02720A" modified="2024-05-29" version="1">MGSFFIALALSLPPLFLGAYGYDETADFCWYTRSYDVVFAGLFISPFKWATNYLPSIIFIAYSTFASVRVMLRLRRAQLDSINVNQDSKNSSQRQNAKTQKIVAKLVSRLMFYPLVPLISNFFNIYGEADYAISHTNKFSLLVPALTGTSIQGLLTSILFFTIDPAWTKLYIDIRKYYDPHFEEAKSSSASNTGSGFESMGKAVSSVGQNQYHNTYHHFEGPKVISEIRTPATKEGVARFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYL5</accession>
    <name>A0AAD5TYL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA(Adenine34) deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TAD2</name>
        <name evidence="5" type="ORF">HK099_006138</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000510">
        <property type="protein sequence ID" value="KAJ3215915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYL5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF149">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="173" mass="19274" checksum="D7A986FA163B0089" modified="2024-05-29" version="1">MKEALKMAEEALNLGEVPVGAVFVNNLSKEIVGRGRNNTNSLKNATRHAEFEAIDEILKKQVAASEVEWKLLTVFVTVEPCVMCASALRQLGLSMVYFGCNNERFGGCGSVLSVHNCPSKFKELPCEGNYFKDEAILLLRKFYIKENEHAPNPTKKTNRLLKIEDLGNLKSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYL9</accession>
    <name>A0AAD5TYL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000475">
        <property type="protein sequence ID" value="KAJ3216491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYL9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004038">
        <property type="term" value="F:allantoinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006145">
        <property type="term" value="P:purine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050138">
        <property type="entry name" value="DHOase/Allantoinase_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668">
        <property type="entry name" value="ALLANTOINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43668:SF5">
        <property type="entry name" value="AMIDOHYDROLASE 3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="440"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1014" mass="112729" checksum="34B70151EC1B193F" modified="2024-05-29" version="1">MPTRRNSQEQVPLLTDVERLENNKQTYCTNKQKNFALVLIALAFVSLLGFTIGYWVTPHSNYYSTTESRGGIPSSAFVHGLSQCEKIEREKVKQTETIAPEKRKRNPRYGLNDEYTKPVLIQNAFLLDDGLEYPDVDILLFEGLVVKVTKTGERIKLSDFLTKEDENEVQIFNVEGRYVTPGLIDIHSHMGTDSWPGLDATSDTNEMSSPVTPFVRSIDGFNPDDPAIAIINSGGVTTSLVLPGSGNLIGGEAFVFKHRRFKTNLAEYMLLNAGMKEEDGKKWRYIKMACGENIKRSYGSKGVMPESRLGEGFLFRETFQTAQKLKEEQEDWCFQANSAKSKFNEASNNYIQSHFPEDTRRETVVALLRGDVKLHNHCYETYDLEMMVRHMHEFDFKVTTFHHALEAWMVAPLLHRENISTAIFADHWGYKKEAYGTSVHAGEYLTDAGVDVSYKSDHPVLNAQHLIFEAAKAHHYGLSAELALKSVTSVSAKGMGASNRIGRVQTGYDADVVVWDRHPLELSAHPLKVWVDGFSTFEHPLTNFKNKKPEEILKKNVKKGNEEKSKLEQLEATEILTDQLNYYVKNIKTIYADEKTTIESKTEVGDLSLVVKDGKLKCIGECDLSKVEVDSSFKKYDFENSVVTPGIIAGYGRLGIEEIPSERMTADGVSKGYDLETGGTRGVDGLRVYKNGSKELIAAFNAGVTVAVSLPRSSGLMQGLSVAFYTGEDNFRTAVLKEVTGVTVVMGNDAKDGATLANSFSGQLFSIRKLLSSQIKPVAEHFIQNKKDKYLSYDEKVSRSTFFDVVKGTLTLFVEAQEANDISRILKLKNDIESNLMFEFKQNGIKDIAVPKIKMTIVGGAEAWVVADDLAKNSVPVILRPARCVPGSFATRRCILPGVYPSATELLRRAGVKVSYANVEDNLIRGLMFEAGWAFSDSNDPNAPANETKMSRSEAIGTITWNAADALGIEGLAGRLKVGNRATFNVYSEDPLKLGSKLKLVADGKQTVKYPKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYQ3</accession>
    <name>A0AAD5TYQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001106</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001293">
        <property type="protein sequence ID" value="KAJ3204510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYQ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053211">
        <property type="entry name" value="DNA_repair-toleration"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48060">
        <property type="entry name" value="DNA DAMAGE-REPAIR/TOLERATION PROTEIN DRT100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48060:SF21">
        <property type="entry name" value="L DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3204510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="429" mass="48010" checksum="C8F327977B0D342F" modified="2024-05-29" version="1" fragment="single">YLNGNDIIGQIPSNFEKLVNLTSLNLSNLNLIGVLPAKMLCFCKNLEKLELQNNNLSGEIPKEISNLKKIVHLDLSHNLLEGSIPESISELKNLVYLNIECNFLSGVLPTGLFALTNLELIDMSNNSIGGCIPREIENLKKLTFLDFWCNQLSGSIPETIGKCLNLSHIILSGNQLSGNIPSELGNLTRLIHLFLNANLLSGNIPESFSNFNLMTDLNLCKNRLTGNIPENLSFCSQLQFLDLSKNLLTGGVPETFGNLTNLKFFSVKKNLLSGTIPETLSSLSLIENLFFSSNNFTGIVPESFSFLENLKILDLSDNEFLSIPDVLSNIIKSTNNRLGKQDSVQFDIERKRMENIDVIQSTLERVNLMRSDTYKPGVLKKEVKVQTKNSIVKKERIDYLFNVLKREVFKNIAVPKLATFVRSLTNRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYX1</accession>
    <name>A0AAD5TYX1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-chaperonin molecular chaperone ATPase</fullName>
            <ecNumber evidence="4">3.6.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Immunoglobulin heavy chain-binding protein homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KAR2_1</name>
        <name evidence="12" type="ORF">HK099_000954</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.10" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010001243">
        <property type="protein sequence ID" value="KAJ3205007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYX1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006986">
        <property type="term" value="P:response to unfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10241">
        <property type="entry name" value="ASKHA_NBD_HSP70_BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000153">
        <property type="entry name" value="Endoplasmic reticulum chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042050">
        <property type="entry name" value="BIP_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3205007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="619" mass="68585" checksum="AC736ACBF2333174" modified="2024-05-29" version="1">MKKNCVGVYQNSRVEIIANEQGHRITPSYVAFTAEGERLVGDAAKNQAPLNPYNTIFDAKRLIGRDFEDKNVQADLKHFPFTVKEKKGKPIIQVEIKGSKKNLTPEEVSAMILAKMKAVAEAYLGYKVTHAVVTVPAYFNDNQRQATKDAGTIAGLTISRILNEPTAAAIAYGLDKMDGEQNVLVYDLGGGTFDVSLLVIDDGVFEVLATGGDTHLGGEDFDNRVIEHFVKLFKKKHSKDGSKDMKALGKLKREVEKAKRALSSQMSVRVEIESFMDGIDLSETLTRAKFEELNMDLFKKTIKPVENVLRDSGLSKGDINEIVLVGGSTRIPKVVKLLEEFFNGKKASTAINPDEAVAYGAAVQGGILGNGLKEDRRLNQCVVLDLNPLTLGIELDGGVMSKLIPRNSQIPTKKSQIFSTASDNQVSVLTKVYEGERPMTKDNNLLGTFELTGISPAPQGIPQIEVTFEIDVNGILKVSAVDKASGNSESITINNEKGRLTELEIEKMLEEAKEFEEQDKIFKELVDAKNDLEIFIKDLKISLDDDDSELSLHLIKLDKKKFFFDLLNKKSNWLKKNTDTSNTDFFNLNPTDFVNQKLEILSHLPHTDDDDSTSIHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYY4</accession>
    <name>A0AAD5TYY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000476">
        <property type="protein sequence ID" value="KAJ3216484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="322" mass="36419" checksum="04E4A980CB6921D5" modified="2024-05-29" version="1">MLTPKDVPPEYFAINASSSKPVKYAMVNGVILLNRAYIRWQKRNLNPTTLINAQSALPIISTMEDYNEYNITLKEAGLSERLLSETTTQVFENIEDNEYLSKVGTDAEDLFNSIQKIFSFYEIPIGFISMLYKLEALHCLDFVIDDANVNKDVLSIPKKGQSPKEFINEANAALDKAFASTPTVSTTYYEAIKKVLDNTDNSRVANYFLFTSMPISEERKKITKLIFSLKTKFEKHPLSLICFDEDSNESWNGNLHGIPFFTYVESFSKKRDKVLKDQGVGIPFSKGFYLMSQLLSLLNPKSLGAMHEVNYGLLVKGTAPFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYZ0</accession>
    <name>A0AAD5TYZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000721">
        <property type="protein sequence ID" value="KAJ3213336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYZ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="115"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="264" mass="31266" checksum="B8C5E4B32E765E03" modified="2024-05-29" version="1">MNLLNNFENYSPNLDKLLKLHLTLLLKNENLKISNFFLEKVFHAASEIKPSVEIVLLGYLVTYNRKMKKESKDFFENCLFNYFVNLDDNQLEDYKTLCKFYCLEVLGKNAEYDQIEEFLNENDVLDDQLKNELRSHVENIKTVEKNNKKNDKLKKNKEKLSSLNKSEKKKNLINGVAEINDPSDTQNKQQQEKEVKNLECTENLSVEEKNNLKDTKKENLVEKSNNQELIKKSNQLNLYKRFKENRHLILRKIFNTFKMGSDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ98</accession>
    <name>A0AAD5TZ98_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005377</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000414">
        <property type="protein sequence ID" value="KAJ3217691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03139">
        <property type="entry name" value="GATase1_PfpI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06627">
        <property type="entry name" value="STKc_Cdc7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF4">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="229"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3217691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1287" mass="147639" checksum="530DE715B500E770" modified="2024-05-29" version="1">MENWDTQKPRTLGVVLYEGFAVLDVFGPVQFLNVLSNKFPLKVVFISENGKDVSTKPPIPHPNSIFPQSYQVVKTDYSFETCPHLDILFVPGGSGVKLELQNKKMLNFLIEKTKIADLVITICNGSALYAKTGCLDGVKATSNKAIFALAEENGPAVNWVKEARFVYDKKFLTSSGVAAGMDATCYFIKVCYGEEEMRNLSMIIEYKPQEDGSQDEFAKLHKLARIEDYILGNCIGKGAFGSVYSGLNERTGETVAIKQINLLNIPKCEVDLIMMEIGLLKGLNHPNIVKYKGFIKTQENLNIIMEFCENGSLFHLRKKFGGFKENLVSNFVHKILLGLIYLHEQGILHRDLKCGNILTTKVAEVKLADFGVAAKLCDVQIDNVAGSPYWMAPEVIELNGATTASDIWSLGCTILEMIVGNPPYHTLAPMSALFRMVQDDHPPIPEYLSPLLRDFLLECFQKDPYLRISAKNLIKHPWIKSINGQPKSSSKVSEVSEVIGVKESWDEDFQENELEAKSMLLKNVKSLAEAEKMSSNWDEDFDVTNEKEFSFENCQKKKKDLPFHENEVFTRNEKLLGKELSKYNELAENQKLQLTNNSGLKGTPKKNFGYILPETELENNWDNDFEVEETHSNLVSAKQLTNLYDSEIKLNTFSAVEENLDNVHRFLDEENGNDWSDIFNFNVTLEKNRNNFKCPDSFEEDPFSNLEDNDENLENDANTNNWYISKSFEYDLKEKLNNKFDVLINNKTLSDQELIKICEYLGKTFLDNPIQKSIILKSHYLMPLLELLERQTKEFVILKLLKFLNQCIEDSVEILESFCLFGGIPIMLKFCKKYYSIDIRIESSIFIKYLCKNVEILKIFISCNGLKSFSEFFDEENFDINKKVLVENAADSIISVLNIQSVSKKDFCIIFTQEYLLKKLSSTFYVLNLDNSINLGKNEDLIKKILMIFLNFSKGNLKVMSSITNLNCFINLIKSFELLNSKNLVLLLKILKNCSMNLNVKVFENFEKSNLIFELKKILDYKNINSEVNKHSLVILFNVCRMSKKRTEICAKLGFIPFLKKIIDSSSSSRQFAIQIICDMVYCTEEILKNDVIFVYLRLLEEVSWQENVLKAILALLKESRNTKEIIEPILLNNLKSVLTNLQKKNFFFSTKTSKNENLSLNKLLELFLNLINTSKKFNLRILLSMKKELDEENNFFQYLAFGLLNLKNISLMIILLKIFLSFKVNFGKNLAFFTGNFDLQHHKDKFGLNFLDYYNFRGTLKTVQDREPSVIVQNLIMSFYSGESIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZD5</accession>
    <name>A0AAD5TZD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005353</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000410">
        <property type="protein sequence ID" value="KAJ3217785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZD5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="622" mass="69005" checksum="DC99557CC15DA536" modified="2024-05-29" version="1">MITVDQIHNLVVGDVVEIFDSIPNIDGEFIITGISTQTTFNITSTINYDTTGILTYFGKVRTKLVNNLSVGDIGVELNWHNGNSIGTIDSRIGFFGFDIGDKCWTFIPEAQKVGKRYFGDKGTLCVGIINCLGINLGGSMNTGNNLISGSNFLITGGNINGVEITNSKGSFTEICINKLVCNLDINGNQLTNGILNGVEITNGKGSFTELCVNKLVCNLDIIGNQVLNGNYLNSKGSFTEICIEKLTCNLDINNYNLTNASTIQANTGLFTNLNVLKTFIINDVLPALKNSKYKIKIDSVIDTSVYREGLFRTIYSTKSGEKRPFVFCKSGDEFEDMDSFIACPVENSQIFEWENGSAGSSEIGGGNKKPIKRKASVKNEKASSKKGKESVEEESSQVGSSIDLNKQDYAELKKFIRDEFNYSPSSLSSILLDSSKNCIIVALVDKYCKFASREHKSNFQYLLFNSLGCKKKCHDVDCSRAINAEILFKDLPEKVKIILNRVLKLEDKDINLLDVATTECTRYIKENYDENISPLVYDKNLNLFKSEATNSSIVNLVGKCEKCIFEHQISTNGEYCIKCKICSSMFPTDTHIKIPKHTNPTFYQFIQNNTIIINNNYGAMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZJ3</accession>
    <name>A0AAD5TZJ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001060">
        <property type="protein sequence ID" value="KAJ3207350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZJ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="181" mass="20007" checksum="83B8B9494B06DB48" modified="2024-05-29" version="1">MTLVDACCTLPPCKSDYTPKGKQFDLGNLPIYEIGNATDKAILVIYDIFGYHPNTKQVCDLLADQGFFVIMPDFFRGNPYPNVVPVDMTKLMTHLNTVVPPEVMERDIKNSYDYLLSKGAKNIGLLGFCWGAKESVTAASNNKRFKAVAAAHPSMVSVKSVKNLEAPLFLIPTKDDPDFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZM2</accession>
    <name>A0AAD5TZM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000391">
        <property type="protein sequence ID" value="KAJ3218205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZM2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044852">
        <property type="entry name" value="WBP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606:SF1">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="178" mass="19998" checksum="62054257E6ED5525" modified="2024-05-29" version="1">MSINAIETDNSGQPVLFQGEKLFNYQGGVWLEFQCDDKSSDDNYVTKGGTIYQTNLRLIYLTVPRLDIFKSFSVPIQNVVEEVFDQPNFESKIISNTNENVLKSGNLKLVFKDGGGYEFNQILQQLKCRINGTQFLDGDPLPVYEENDSETGEGSSSYSRGFTDAFDPPSFNDDPPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZR0</accession>
    <name>A0AAD5TZR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001017">
        <property type="protein sequence ID" value="KAJ3208028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZR0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="79"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="329" mass="37256" checksum="150FF933029D3D1F" modified="2024-05-29" version="1" fragment="single">STEKKSLVQSVDDMLADIEGCINQISTNELYQDTPLPPLPMTPPISPYPPYTSFSTTTTNNSSYIGPTTNTFGEISNLPDSFGGFLNKVSYNFLNKKSTKKLYLVLANLTLYLFNSNEDDFKSFEDSLPINKFSHCVESKRGGPNTIYFKTIIQKNNPITVSNEFGNEDIVLNNDVKKTLELECKDKEEMIVWLELINENIIDAKNGKRAANSIMDESLEVGNDKRESDKSYFSNANKSSRKSAASNFSNNSTEESNRLTSNTLGSLSSFDSSSIKLQLGSSSNKETNMFAQNRELDKKEKKEEKKRLKEEKRKKEIKEQMDFVKEEFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U005</accession>
    <name>A0AAD5U005_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000366">
        <property type="protein sequence ID" value="KAJ3218757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U005"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042100012" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="22036" checksum="8112AF6673D56582" modified="2024-05-29" version="1">MKLALVSLLASTLVSSQISPPTTGDKPPPGSVTIGPIIYGGTGCPQGTVSENMNSDGTAITLLFDSYIASIGPNVPVTENRKNCQINVQLNVPQGWQYSIATIDYRGFLQLDPGVVAQQSALYYFQGSVDQDRCTTTFTNANNGDYTIRDKFGLATTVWSGCNAKANININSQIRLTAPAGKSGFITTDSIDSKVTHVYGVQWEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0A4</accession>
    <name>A0AAD5U0A4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription elongation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DST1</name>
        <name evidence="13" type="ORF">HK099_006435</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TFS-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000554">
        <property type="protein sequence ID" value="KAJ3215296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0A4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031440">
        <property type="term" value="P:regulation of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.30:FF:000003">
        <property type="entry name" value="Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006289">
        <property type="entry name" value="TFSII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01385">
        <property type="entry name" value="TFSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="12">
        <location>
            <begin position="165"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="10">
        <location>
            <begin position="282"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="79"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3215296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="37119" checksum="7EF8603EFCCDA013" modified="2024-05-29" version="1">MEVSEIQTLKSQLEKSISNGKVNNVLDLLERLENFKATESNLRLTKIGLCLSSIKKHKNTTTEINTKVKLLVDKWKKTVRESSSNNSSTSSEKHTSIENNASINNKKTTEKPSLPNCNVRKLSNDSNNNAISPASSSVNSPNPSNVKERTFQTDGIKLTSTGSTVRDNCTGMLYSALGLGSEEESDLLLEIAISIEKTVFGKNEKVDQQYKSKIRSLFMNLKDKSNPELKERVISGELAVEVFTEMKPEEMASDQMKILLEKAKQQSLHFAQTPKDNSAETDQFKCGRCGKRRTKYYQMQTRSADEPMTTFVTCLACNNRWSKKYEKSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0H2</accession>
    <name>A0AAD5U0H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translin-associated factor X-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TSNAXIP1</name>
        <name evidence="4" type="ORF">HK099_004454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000314">
        <property type="protein sequence ID" value="KAJ3220132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0H2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032755">
        <property type="entry name" value="TSNAXIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16306">
        <property type="entry name" value="TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16306:SF0">
        <property type="entry name" value="TRANSLIN-ASSOCIATED FACTOR X-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15739">
        <property type="entry name" value="TSNAXIP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translin-associated factor X-interacting protein 1 N-terminal" evidence="3">
        <location>
            <begin position="23"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="122"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="584" mass="68667" checksum="4F7614D159F4E45C" modified="2024-05-29" version="1">MSFLTCFVGDKTKPKFLLQLIHFMQRELRLLGGENSATGDPRRLQVCREAFSCFIMEFKTYEKILTEIKNEYEFNFLKQRAQIEKLMTCESKASILDFQNSQKIEKVKLEWETATKDLKKENLDLKSKSEKDTNKINNLEEQIQLLNDEIFIQESAHAKEDFLRKRVLELQDYMEKEKQSYEMKMNEKYNIISELEEKIHIVCRENEELKNCVMKLENATENFVDRKIYKKLEVSYSDQKIILRENQEELKNLLRNDVSTVKKIEQVQEENQNANLQNCIISGKYFIGLGSTSEIPKVLRFKGKILNRKLTKMDTVSLIKEVWKSKSLQKGKTTDCVSLEEFLYIYLKKKFGSQERICEWAYNIFESARRYSFACVECLMFFNILSKKCNESVYHYVSFRTERLKESFLRTDAQLHNAKPVGYLKMEDIINVLKTFGKNSEEILELKQIIEIDQKESEINLVSYRWLFENNCGESMFVNVLLGQELNLMNNYLSGLTKVLKEGTGKLDNALISDITNIFIKYDTLKSLKEQNKYLERGFGVSNLIDLKVKEFSKALFLKNLSMGVVILGNHDELLKSENFQQFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0V2</accession>
    <name>A0AAD5U0V2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000601">
        <property type="protein sequence ID" value="KAJ3214662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0V2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="79" mass="8921" checksum="F6F5FA1C9867AE11" modified="2024-05-29" version="1">MTKFFGFAFSQFVSGALVSCIIPSILVYIPNFYIKEEYGKRIVLIFSIGDFCGGLFGNLFSVLIGKLDLNHDNLKSWKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Y4</accession>
    <name>A0AAD5U0Y4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000272">
        <property type="protein sequence ID" value="KAJ3220809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Y4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="entry name" value="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987:SF1">
        <property type="entry name" value="OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="UraD-Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="263" mass="29609" checksum="50E50C00910FB46E" modified="2024-05-29" version="1" fragment="single">MSSDLVSISELNSRDFEGFSKIIELLFEPAPPLSSKLYNTCRPFDSYKNLLKATDDIIKNSLTEEEKIIVINAHPRIGEKKQNLSKLSLAEQGNEEDQEILNKLKDLNERYEAKHGFKFVVFVNGRSKSEIVPVFESRLNNPTELEMETGLRDMGENAVPLHCGKGNSDKLNKVLNSKNSSVKKIYSDIIFRIESDRSSIGSNSSMESLENHLGSTSISASKHNKFSPYSQSYCLRSTPLYNKSTKKIENLMGFQCPVDISSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Z4</accession>
    <name>A0AAD5U0Z4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000433">
        <property type="protein sequence ID" value="KAJ3217311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Z4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="2">
        <location>
            <begin position="19"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="223" mass="24856" checksum="092622BA702ABEC3" modified="2024-05-29" version="1">MSNTNYYSSLYAPPNPECFNCLLPAFECYNYANCSSYSGKCICPPGFGGDDCSNPLCDSLPKKERMKRPPDQKSCTCDEGWSGINCNLCETDAACNPMMEVEGQNGTCYKGAITVKNSFVQCDVTNPSIGKLLGDQTPQATLSCEKVSNSCSFQFWSAEEESFYCKLTDCKFEQDIKYDKNITSYDCNQIECKCYPGRLLCGKDGSVDLTEWFESKEEGRLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U180</accession>
    <name>A0AAD5U180_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PKD/REJ-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000252">
        <property type="protein sequence ID" value="KAJ3221091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002859">
        <property type="entry name" value="PKD/REJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02010">
        <property type="entry name" value="REJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1329"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="domain" description="PKD/REJ-like" evidence="2">
        <location>
            <begin position="572"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1462" mass="164813" checksum="FF418D748E25ACEC" modified="2024-05-29" version="1">MISHFYEHLMCAIYLIKSLYVEAAPLLITGIAMVGVLIATLLLKETAVVTAQLKEQERHMIYVVFVEGIVPLAWTAKESLLNISKINGTKIMDTCGLCDGDGTSCAIKLTAVYPAIIPNSQSAVIRLYGSNFTGEAMAVYINETIVSKTLVTVLSPQLLSVTISEMYLIDKDPVKLFISVSQNNVIQTNILEIKVYRPATVDLYHPTIYTSNSSNTLTLYGNNFLIGETGYCLYETNPIQFTKLNTITETVAECPSIIYPKTGSVIVRAFYGEKNGITINSDIFFTSKFVLELKYYEKSPILLSSTFVDPGNSIKLLFDAPITAVQSNKTGILNSETNYCLNYFESTFEGKLWRPKFEMDCTAYFISKTIFNIKINSFVSLFLPKMQITAGSRLNFTKNRIFRLGSVTQFKRSFEEEWIVKAPDTVSFQYLNLMAPSSVGNCDDLTFDLTSVGNAGGHTFTSASINFTSSVFENTDSTLNAFLSILSTKFVNGSRFLSIPYNMLSEKTYNFQFTAQHMFGHISETKVVKKFNRINFPQIYIKALNSLVDFSTYNVYSAVISQQCESFAPVLVILQWNITSVDGTHAPYIEYSNDTNLIISPFTLKENLHYTITLTAGYVGFPPVISQYTILTKNPSLLVDAKGSKTVGIQNDLTFTAEYKFIGTHASETFLFQWYCFTTDLNPCVDLTSSNNSLLFIPAGLVIKLNRKLFINDFIFYFVAKSVSTKLTAVSDPAYITITSGHLPIFRLIFSAKLVVPNDDSFFIAPEVDINSVTSKVNKLIYKYEMLSTCEGKYFNTIDVSDPTFVKTPNSPILTFQKSALKSGDSYCIKLSVTDPGNSQVGSSYGIFSVLENPQGGFCKLDSSSVGIEFLTVFTFQCLYWVTDPLAYPLRYLWEIKNSNNDSDFYKLTTASTSSQFSSTFPAGRYTVKVTILDKLGSANSVEQLMNVTVTESKLLQSNLKESINVNSSDFNFLKAYFEQIATDFTFKRNIDIFLGNLSLISNIPLLFTPNLTSDLGSLLISNLTSVIRNTNLHADVHTTNFIIDILYKMSHFALKQMNSVDMDGIFESLFYIVQRFKLIFQYSIDVVKKDFILRVITILDNISATSLISDIQLSKFQQTNEIRDLISTFYSKSLPGGAEILSVNGTSTNINIGQVNLVDLYTLQMGNFFVVEANMDFLYEVYCIKFFSGLVTSKFKLNYEILDGVLDLNSYIYDLKFSFSNLTEINGKAITKIKIHIDVDFSFAKRNSITSQFNLNSNETNLYCFWSQADMKVWSKEGCELTYVSSKKAICNCRYQGTHWALGIYKSNKNSTILPIQDNSETSNLPTIMIILIILLLISLLLILFYFCWKNKIKLKTFFNNIWTFLSEKIIYPGCFTKKKKKEKQIYPTDNNWNVNYSSQPEKESPLLIWGDGADDVSEIRIDLEESPEDELNADFQVYSFEEKEDDLEAIITDINWPIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1F0</accession>
    <name>A0AAD5U1F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000249">
        <property type="protein sequence ID" value="KAJ3221132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1F0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="57" mass="6246" checksum="FA3105A0E2879BAD" modified="2024-05-29" version="1" fragment="single">QNAENKGTAEEGSSGTQLAFFLDKLNIADPAETKTYSHILNISATRNNTICHLGIYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1L1</accession>
    <name>A0AAD5U1L1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Notchless protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NLE1</name>
        <name evidence="6" type="ORF">HK099_005442</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000423">
        <property type="protein sequence ID" value="KAJ3217508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1L1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="8"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="50"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="130"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="256"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="298"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="340"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3217508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="373" mass="41074" checksum="5301B32FD4B28571" modified="2024-05-29" version="1">MTRCTSTLTGHTEAILQVCFSPDGSKLATASGDKTVRLWDLLTETPIATLTGHTNWVQCVAWSANMSYLVSGSMDNTVRVWDPKTGKNLGNALKGHNDAVTSISFEPMHKNINCTVRVWDATLRKLIFGLSQHTAAVMAVKWGGEDVIYTASRDKSIKLWDSKEGKLIRTLNGHAHWINHIALTTDLVLRSGPFEPNSGIIGVPLKFSSAQEAFNKATERYQAHIKANSEKLVSCSDDFTLFLWDGLSSKKPITRMTGHQQLVNNVCFSPDGRYLASAGFDKSVKLWDGKTGKFLTTLRGHVGAVYQVAFSPDSRLLISSSKDSTCKIWDLKTFKLKNDLPGHSDEVFAVDWCPMGWGGGSGGKDKCLKIWKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1M0</accession>
    <name>A0AAD5U1M0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_005430</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000421">
        <property type="protein sequence ID" value="KAJ3217556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1M0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042184967" description="Cytochrome b5 heme-binding domain-containing protein" evidence="10">
        <location>
            <begin position="23"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="324"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="12">
        <location>
            <begin position="453"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="11">
        <location>
            <begin position="773"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="685"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="687"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="701"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="708"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="761"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3217556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="951" mass="107141" checksum="453E9433CBC0E626" modified="2024-05-29" version="1">MTSLTKFYFSILIITLSPFINASCATPGSPGCNVNGGALTIEQTTFPNLTSYSSKEGNENLLLKNSKLQHFTPVIVPNRLTFFWDILNIGADNETLRGAFEFKSIGFDIDTPSWVGVGFGNSMRTTDFVICHQLAENHNKIHEHKSNGNYEPPPKFKGDWIIKPVSAIFYSNLSEESVFYCEFERPTRPNDFSNPNGAHANIDVQGVQMLLFAFNPASGINVRDEPFTYHSPDHHFNYQANLAGGSLIRVSGQSFENKQVHGIGMSAIWLLLFPFGIFYGRYLKSTSGWILLHAILQTLGTISVIAFLFAIIPEVSNFKASSPHAVIGVILISGILLQLTFGIINALVYFGLNILYPFISPRELSAWYIFFIVIGFWGLLFIATEMFFRISIYRSKKSETIYGGSDFKSVAEKFRNNDKGDFSNVESNQTAIEKIISGQQINKDGFKERSADFKFFTWETLNKEITDSNKIYVVANGKYVYDCSKWINSHPGGQIILYQVAGTDITTDYFFEAGFDAEEFTPKFFKPRLPGGKLTRRNTNTPSICSGQSGHLEPSLFIEAAKNAEILTEMEWNTIVKARRTHIHTKLAIEKLASLLIGELQADTGGNSRMTLDTRSPKEFDRFEYRRYGLIQKRVSSDPTSKNLILNLKFCDLYPFLVKENEPVKFKAGECIEIQIRINGSWVSRYYTPMGTLKCFEINIKIYPNGLVGNFFIKQKLGDRQFKVRGPFGDTLFDPSKQISNRTNDWLPDKLFMITAGSGFTVSLQVIHILLLPTLEPIRVFANFMKTNADELNVMAGDTILIKSHTFDGWAYAVNFSTRQEGYIPLTCTYKTRTKIYVINCVQDSKDIFGLQILDGAQIAYSNNIQVNHIINDGSEISPREHLSGYIRQGKFDQSMFNEIVGEVWVSSGSNLAVVVGPDSFNSNVVDYLTEIGAANSEIRIMPSRTYIEYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Q0</accession>
    <name>A0AAD5U1Q0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Metaxin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MTX1</name>
        <name evidence="10" type="ORF">HK099_003370</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000221">
        <property type="protein sequence ID" value="KAJ3221583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Q0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001401">
        <property type="term" value="C:SAM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03054">
        <property type="entry name" value="GST_N_Metaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019564">
        <property type="entry name" value="Sam37/metaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10568">
        <property type="entry name" value="Tom37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01180">
        <property type="entry name" value="SUF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal" evidence="8">
        <location>
            <begin position="25"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="9">
        <location>
            <begin position="172"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="347" mass="40444" checksum="B2964DC26BFD58D3" modified="2024-05-29" version="1">MQQNQNLELFVWGKGYNNESFDPFCLSVITYLTFLNVPFVLNNENNPQLSPTGTFPFLRDGSTIICGTLNIFNYLKKKGHDLDHHLSSKQAAESLAYSTLIEENLHLALLYNWFLETDNYLKNTRPWFSRNYPFVLRYQMPSRLQKNATVRLSGMRFVDVSGKKTPEVYVEAKNIYENFTKKLGNNEYIFGSKPSSLDAILYSHLAIHSYPSLATPTLFSILTFNFPNLINYVEKIKTIYFENNWKENLVTYSPITKNFFLRLLENPKLTITETFFSNKYTNTNDQKNVAEMELVKAARLENFKRLAFVLGSLGFFVGYVLRNDCFSAPIEEEENDDEYDDYYEEEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2N4</accession>
    <name>A0AAD5U2N4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000405">
        <property type="protein sequence ID" value="KAJ3217887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2N4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="523" mass="58856" checksum="3DE39B0A3524617D" modified="2024-05-29" version="1">MSLLTQSPTNISLSKVTFRREQHLKSKTMSPFNLQQEDENTISPSANQNIQQKSNYIQSPFSTQKHHNSFEHGTNGTHLNHPSFKNAIRPNSHNNRQRSISPQQKNSLENNDFYGSPKQKTFLNFDDAPPINNLYDLNNLDNNANQVDDEDMLDVGFAGNQQMNFDTFESQKQKFKGNTSGPASQSPMLPNFPQQFNSSTHSSPFITTVQKNQPQSPVYGGLPLNSAVSPNSTYNQQQFNAGAGYGSNFTTSSQQHFNNTNQNVWLNPSNYKCLPNPLKELFIQQTGGDSSSHKFPFSIIVFGFNFKYFENISEIFKKYGKILTQKIFYFESSTEKITEISGSENLFNYNDVNFNMSNNGMMFLEFDNKLSFEKSFGLSGSVVWISNTMFVLGTIIYEVNFLKKCPIIGVIPASADFSYSSASISQGSKPLLQKVQRGFSFSFSNKAETGQISEKQKPPESDAVNNRMNTINNNNVINKNNLKQNTSIKSTLVTKQNNGNSNESGLKKKTGYIEYLSEALFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2U5</accession>
    <name>A0AAD5U2U5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000183">
        <property type="protein sequence ID" value="KAJ3222274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1510"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="315"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="446"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="672"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1362"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1510"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1539"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1554" mass="178465" checksum="8F923D7E5DD501AE" modified="2024-05-29" version="1" fragment="single">MDEKGDSAKKNAWSTWNPIGSSSNLINKALEKSKEQLAKVQTTLNSPDQQERTSTDSLFQNLIRNPTDSLLRKPTSNSKQSFEQPLIEDLQQNNSPSSSPGRFQRSLSSSSVDTLESTNDIPKLKQYELKLGDLAKAYKSLQKKNNQIEAVLVRNTPVESINTPSDLENAENFIKELKLKNTIFTDDINKFTKQISELQEIQKLEAQAKSEMFEALQNQLTEKNKEVQKLKLNVDNSPISPKQQPLIDFSEDDNLQKKNKELTVLLKKTTEQRNKAIEKLKEISEKEKSIVEPNLIDISPFNRTEELERQIKSLIASHQSELQTLQHELNLTKTNNENLEMANAELKTQLTQNSNIFNDSNDTNFPTQIKSLEFKLETIENEKLKLQNLVSVQQDKISSLTQMIEKSGNLIQNASVGSTHEIDSFRSCTSVFDEEAMKSQKQSVEYSNLLKEVEALRLEKQKLEISSSKEITCLKDNVSNLTKELNNLKVANDSKKTSEELKELEKKLADAISNAERKSNLAEKLVLKVRGLEQKLLDTTQTAEKSMALQDNIKQLEVELQNYKDRLQAENEAHMALNEKYAELEQNFETKSKKFEEDWKQVVHLEENLNATTKSLNDLEVAHDRSKKELNDQLKITEKFEKLLAEKDSSLLKIENQLNLISSDSDENLAQLKIKTQHLEGLDKEKAFLQEELNLLKISEKKLNDELKKLSKEKFDMEEVVKSLEKEKSNFQEQLKHFNSLDDANKSDVHNLKEEMKKLTLKIESLDNVKVELENNINAFIAKEKSYEAQLISSNDKLLKAEKSYSESKSENNVLSTELETVKNQLQRSNTLCEELRGQLNNGTENTDGSFTELEFKLKDERDKVDKLELELKLSNNLVEELKKKVELLEKNNSELKEELKKVAALKEEEKQKLTSDYENKLKGSAEELRKLEFKAAELKQNFNALEQSKDLKIKEISEAREQLSKQITELQATNAKVYSEMEAVNKNLELNTTEKDEVLSEFLLVQSALDTKSKLLTETENSYNQLKLNSETSKSELTQLNLDLNKLNEEKQVAINTVKELEAEIQSLRGFLEAKNAEVIDHSADNELKELREKVGVLEKAVEESRQASAEASQLKSEMESKLEASEGALALAKKQIYERDNSILEFNEQLKSTKQALTEEEEKKNKSIGLLRNSKARILKLESDAKSKSSEIEKANEYIQEKEKLLKEKDLLLKEKEKQMSTLTRQVEDMNSRLKKHDEGKGDLEKKKKEMTAEVEQLNNKITQLLEAQTVLCNEKDALTSLLQSKEQEWANSTSVLNHHQDLLRSYPITIKELETRIHNLDQDLETSNRLFETKSIENDQFKLRISELETKIYDTEESENRKHDEIEQYKRDIKELRKELHIKNSEIKKIEYEIKEVKLSANQKNEESEKKIIFAEKSLEILDNLNDELKTLTETVNNLEKDIAMEKKKNSELVSLMESKQQEYRESLKEKDNLYEEIKVREVQTKNVCKALKEEVRKLSKSILTSNVSGSTQNLGNGSPINSGGRSSVVEERSSTFESPSSTPTIENYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U335</accession>
    <name>A0AAD5U335_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_005865</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000479">
        <property type="protein sequence ID" value="KAJ3216436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U335"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF14">
        <property type="entry name" value="GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="15">
        <location>
            <begin position="2"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3216436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="544" mass="63225" checksum="BE121BF910DD4986" modified="2024-05-29" version="1">MSQEEKYRGVATYIPVHGDEIKLSPGDQVVILHSYDDGWVLARNFTTLAVGLLPRNFLVNDENSENENNAATPKANERRSSLVVRQRRSQLVTTTPTSLNQKRLHINVSIALFIVVIIYIANQQLNNFNEIEEDLIDLDYNDNQNNYVYRKVGQLSREEELNNLDEKFFQLMLDRERQNEEEEIQRKKDLQERERGFNSWENVDDFIIKSEHFNTELEELEELDKIFYNAMKEKEKEKVIDTEITLLDTPKNHTIVLANQVIQSFKEATSDLKDEVDDIKEIVATSSVAKVENKNKIEEKDLLFIVLTSEVNQDSRVRAILNTWGNNTNSKILFFTRTPSENLKNLIVLPKQQPVYNQHKELFWDALKYAYFNVQPKTKAKWIITVTDRTYINIKAELDYINFKEGNGVSWYNSHILGKCLKTSIGYKLTYTDGATGNMLSSKLIETLHKKGYFNEDKSFLKLTDELHLSNDASLGFIVNKIFGDTLVYSCGFKEDSLFHHRCHYRRSTSSSVKCKSIDCVAFSSCTNSEMQFWNNHYNFVLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3J3</accession>
    <name>A0AAD5U3J3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease Z</fullName>
            <ecNumber evidence="4">3.1.26.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ELAC2</name>
        <name evidence="14" type="ORF">HK099_004130</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000285">
        <property type="protein sequence ID" value="KAJ3220632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3J3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990180">
        <property type="term" value="P:mitochondrial tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07718">
        <property type="entry name" value="RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047151">
        <property type="entry name" value="RNZ2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027794">
        <property type="entry name" value="tRNase_Z_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553:SF49">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13691">
        <property type="entry name" value="Lactamase_B_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="13">
        <location>
            <begin position="450"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="732"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="733"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3220632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="820" mass="93408" checksum="D4AF40CC600B9E40" modified="2024-05-29" version="1">MLYSFQILTVPGPDSGPSIMFTFSDKRYLINCGEGTQRFCQEHKVKLLKLKSIIFTKPKWSATSGIPGMLLTTADQGLTELNLIGPSNFGAFVNATRFFRNVNSMKTNYMNHNDSDKFIFEDENLKIESIFTIPCITGVKRKMSDEEEKVECYQKYCNKKENLPVFSYIFTGPEVRVSDIDIKKKKKVLNNSPVGDLSEGKSVTLEDGSVVHPHQVLEKAKPILKTIIIECPKVDYIESLISNQKFDILYGKNDIENPIGFIIHIVGDGVLNDKRYIDWMNKFCPISHIILNHEFNPHEVIFVGSSKLQRDLNYLDEKIFPLPYYNVEPLKSFTNLDYTLPSNTILGEPLMSVVISPNVKLDYSESIKNSVDFLRWKILKSNTELVLKPKFLLEPFIRRCEAAKKAIKLKEKDLQNLNNENLEVDKDDYYSKTFIIPLGTGSAIPSKYRNVSSTLVILPSKSVIILDCGEATLGQIIRHYGPDTTNNEILKNLKLMFISHMHADHHLGFLSIYKKWLKVRKPNAQLNVICPVFFVYWLRDYNVFEDIQLANLNLIDAQTFNALTLSNVLDGNALKFFLKVGSVDKNRIQKIKKGLLEDMGVKNIEVAEVKHCKEAFGIAITDHNVGKIVFSGDCRPSESLITIGVGAEILIHEATFEDEMIEEAISKRHSTIGEAIDVALKMEAKRLLLTHFSQRYPNLPSLNFDSVEDNKKLTVNDMKISAEDNFVVKENVTESGETPSTSISEESTNNKNSEKDIILASTLRQEKINKSNLLIGVSFDSMRINLKDFWKLQYFIEPIKYLFNDEGHLIDNRNNFKNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3M8</accession>
    <name>A0AAD5U3M8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001242</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ZNF598/HEL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000133">
        <property type="protein sequence ID" value="KAJ3223366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3M8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16615">
        <property type="entry name" value="RING-HC_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041888">
        <property type="entry name" value="RING-HC_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056437">
        <property type="entry name" value="Znf-C2H2_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044288">
        <property type="entry name" value="ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938">
        <property type="entry name" value="ZINC FINGER PROTEIN 598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25447">
        <property type="entry name" value="RING_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23230">
        <property type="entry name" value="zf-C2H2_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="71"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="430"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="503"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="694"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="750"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="503"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="514"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="710"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="757"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="783" mass="89173" checksum="3F7FC8E11FD5B487" modified="2024-05-29" version="1">MKNEDSTITDSAENLHDENKSKRKNEIKKNKFINVNEGTVSKINNLNKKIDKVITLNNNENKKEDDNFKLCLICTEEIVWFAFGKCNHKICHICCLRLRGLYKSNSCTLCKVECNAVIFSNDCTKLFKDITLSDLPFMDKKLQIYFDNEEIYEETMILLRLNCPDPECEVYCASGWNELKRHVKAVHESMMCDLCIKHKKVFTHEHTLYAQNELSRHYRSGDPDDPSFKGHPECGFCKKSYFQNDELYEHCREKHEQCFICQRKGVRHQYFRDYKELELHFRTEHVICSERECLEKKFVVFDSDIDLKGHQIEAHGTYGKKGAVVDVNFSYHNSSASDYQRSNRGRGRGRAQNSSEDSVSSRLPLQTQLSSSKLDRNSGVPNSLEVQTSPSNFEQAPEELSSTEAFPHLSKVNPQVNLPLQAFSKRLQGNQPEDYPALSPSSSKRSSSKQLSEREKFSSANIANNKSVQSKKEEYPALPTNAIKKNKGNVNTRVIDSSSELKTASAASFNHQTSSKNLSSSSPQNPKQKVNDPVSNKLEINKNTPEDPDILLGLSCLLQNDKTRFQDFKTLAANFKNSNHSAVQFLEAFAKLIINKGENSLTDQFSREMILQIGKVWKKLAISLNDDSKHDKMLQAWNDFKVKQKCYLEDEFLSNGAKPYSLPNSSSSPQKKILVIKSNASRHRFVQKPIIPVNNKGKESHSQSIWGKNASREDGNMENKNAPDAENFPTLKYEKVAGIQETERNIFENTGSVWKGNSRESAETDTNSKTKKNKGKVLMKIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3R1</accession>
    <name>A0AAD5U3R1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ropporin-1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ROPN1L</name>
        <name evidence="8" type="ORF">HK099_001162</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ropporin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3R1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22985">
        <property type="entry name" value="DD_CrRSP11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003117">
        <property type="entry name" value="cAMP_dep_PK_reg_su_I/II_a/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14952:SF9">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14952">
        <property type="entry name" value="ROPPORIN-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00394">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIIa" evidence="7">
        <location>
            <begin position="29"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="257"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="264"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="383"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="409"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="462" mass="51536" checksum="79A3D6004F2861F3" modified="2024-05-29" version="1">MTQVASRAKPAPFGAPETMYCAEQIRIPPDLPEILKNYTKYVIKNQPSDIITASAEYFGRLAKQRIKAFNSTKRVTNQQLEAIYKKLTNPDLNFPQSKKSLESICTDVPYAQIADIVTLGGWSDEVPWLKFWALLVAAAAGTIHSTVEVVCEILGDNGSISATPFLEIFQFLTERDPEIPKSASQKILQNLKKNLNNEKLEINFLVEMIKKEIPIKFDYVSPVNSRPSTENKKNNVVIFKQSEVQLETPVVIENAEEVEEKTVSPRQSVPGSRQSIVPESKPESRENKIESRESTREISEFDIKPPSASKPESGSKPQSSASPRESKVSTSHESNTEQRSSKYEERVENSESQGGDKPLTRESTVTTDSKVEGFRVPSVKQLSSKDLDEANKESTETEVVNNNDVNADPPKDDQTEKVPEVENAAIVEQATDSETPYPPTEQPTEPVAVNDEHLEEVTKQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3W7</accession>
    <name>A0AAD5U3W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000123">
        <property type="protein sequence ID" value="KAJ3223619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3W7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="567"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="170"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="643" mass="72322" checksum="B2044378BB7182DE" modified="2024-05-29" version="1">MQRGESIQRNVEDIYGEENSENNSEVSTASILHQNNLNSLSTKLHNTEIAPVSVESNGSNQDNTLDSENAYNQDTYKEAGVDNFDNSCTQTIPKVLPVEHNFAYNNDIKDVESTVIPQNFTNYNGTSTILSTSPAVFTVPTQSSNSQHGSTSSLDLNLQQVFVKYNVGSAQELKELQKKVEENHQSLKAENEAFYKIKMHSIKELDELEEKNRLAEFEIERKRKESKKIIAELQAGNQKLQIAKKKIGHMKAKSGRIFTNVDKDQEELNRREPGHLKLKSTFENSLSKKTKLEADIHNMTEQIKQLSEKNNHDSVIVASKTAETVENKKKLMNLIASIDETMGVSLNNLSELLNTCIAEQHALDMLNSFEQENLQSSGDGGSLGGGLGFSVVIDRSFHHFHFNTKASPSKNDSIVLTSDVTLGLVKTAFLFIIPNQSRANDWWGVKNVADKSENGEIELHNENPSNELRRVAKDDFSSLHPSESVQFLNDLDFLDTYFYFSPESAYKILDDMGETGRNLYLTGFEALDLIFPLIYTTFLISCLHLLFNGSSTFSIMYPVKLDFMAKMASFFNLAKWTLIAFFTLLIPAKFVLNRLTVVTVITSTKKPRSKTLDINSNKNFLATRSTRSNTLPTNTQKKSKKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U420</accession>
    <name>A0AAD5U420_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ras- protein Rab-11B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RAB11B</name>
        <name evidence="8" type="ORF">HK099_001070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000128">
        <property type="protein sequence ID" value="KAJ3223487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U420"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000274">
        <property type="entry name" value="ras-related protein RABA5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="21276" checksum="862FBE5352FDE33A" modified="2024-05-29" version="1">MAQSNSDDYDYLFKVVLIGDSGVGKSNLLSRFTRGEFSLDSKSTIGVEFATRSIQVDTKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHPSYENVNRWLKELRDHADSNIVIMLVADNNLSFIETSALDGGNVEMAFQKILTEIYRIVSNKALESEKQTGANVTAGFNIEIKPTNPGETAKSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U445</accession>
    <name>A0AAD5U445_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000394">
        <property type="protein sequence ID" value="KAJ3218121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U445"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="832" mass="93016" checksum="0BAC8B354A3034A3" modified="2024-05-29" version="1">MEKNLCKCLMLNCNFSSSTEKDTFEHAISAHSTKGHQKCVWVSNKLKGPCNSKFKHKGQFKDHLIIHFSLDFKPYGCCFCEKRYRSRQELGKHKKIHSGDASLSSGKDKLSRTASSIKSVEVTPCSLFDNNLPLSNKLTYSKDNSSTVSNNFSHSTYNNSDQLHSKIDLLSRIDLLENESVQSRSGVNSGKTPLSDEERVAKFHNTDITASPVIRNLVVDETIENSLSGKHMHTSTTRNTTSTQDFVELFKTESDSAYNQSIPLTDYGHPIENLLNTKWEEFLSKKICGTGEICKLADNNKLIASPPASSFPSSSTELEDSLESQEKTVLMDFALDKSTNDSKKLVFNKEDSLEKLKFMTISLTKSPYFSITLNPSVSYFLGFNVSFVTSLSSLLTDNFNVAIPQQFKNTIWSVINREGKTGRVPANFLLLLQKLWINSPGSNLSRKLDYKLRNQIDRSRFVYKDFFDDLIKNINIEINIEIDKLCYENSNKGELALSAANYITNEDSVEYFEPTMESKFYKNLADCSGASIILKYNINYGSEKANLSVRKAILMRSEMEKIIAEEVTKTLNLLLLKENNPSINLTITSSVFSTPLAQNNCRMCTKQVLFCTPQDVCKVGTECVVVPQTCQKCSHKICKPVQLKPSKVGEICNEFTGGNGPSHTCETGLYCKVDPMLPDIGKCHVLPSNEGGPCNEFTQPMEASHDCAEGLVCKTINEQLPDLGGKCVKPVATSLVTLEQVTYQGFATYTPFNPNECTKLPLSAKETRDYSIQLQPYTGADISIFDNDKCKGTPKIQRNWSNVENSQFQQYSDDGDFKKANAKSVYVVVAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U567</accession>
    <name>A0AAD5U567_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">26S proteasome non-ATPase regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPN3</name>
        <name evidence="5" type="ORF">HK099_008073</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U567"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013586">
        <property type="entry name" value="PSMD3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057985">
        <property type="entry name" value="TPR_PSMD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08375">
        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25573">
        <property type="entry name" value="TPR_PSMD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="214"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="427"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="460" mass="52802" checksum="42B075990ADD2A31" modified="2024-05-29" version="1">MSEVLVLQSANACIALITRAVDENEQRLIARALRNTATFRHKLDRTILTKLVVENVSSTFKQTFLNNLKAMDTSEDTTVESVSKKYILSVDYYLGYLILLFQHDSKEISIEFSTYLAQSIPKANKRELDLIAAKVYFYHYRNLELSSNKEFWINARGSLLAAHRTATLRQDYESQAVLINLLLRNYLSTNHYDLADKLVSKTQFPEQAANNQLARYNYYLGRIKAIQLDYTSSNKYLLQAMRKALVTKATSGFQQAVNKVAIIVQLLMGEIPERNVFRQPMLKNSLVPYLKITSAVRVGDLHLFQEALGKFTSEFQRDKTFTLILRLRHNVIKAGIRMLSLSYSRISLRDTCLKLQLDSEEDAEYVVGKAIRDGVVDAVINHEKGYMKSKENVDIYSTNEPQNAFHQRISFCLNLHNESVQAMRFPMNAHKKDLAVLNDLIEEEKKLVNEIANEEDDAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U598</accession>
    <name>A0AAD5U598_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SAT4_5</name>
        <name evidence="12" type="ORF">HK099_007745</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U598"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF558">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="99"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="463"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="17"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="763" mass="87308" checksum="115C08FB735ED59F" modified="2024-05-29" version="1">MSNFPAEIYVQEYKEKKNKQVPSIVIEPLNEHRRQLNPPKKGIFDYSSDTDPELSSGSEDDDEYSHAAKKKRNHGFSEVSGLKNRSNSDSSLSSTSSSLIDGLALVRGRSASSNTSLESSKSFEDLRCETPHAKINLFQGANQVYAVKEFKDLKQDKKKFLKNVAAEFTISSCFDNNIHIVKSFDLLKDKHDHLKQIMEFCAGGDLYHYIQDHSRMSVDVANCLLKQLVTAVSFLHEQGVAHRDLKPENLLFAKEDCRLLKIADFGSSEVFHPPFTSSHKASGLTGSGIYTAPEEFLGVEYDAPAVDIWAIGMIYYVMLKKGCPWKSIEDATFKHYLSNCNAYRGRDFEHFELFNRLENKDSRRLIYRMLDPNPVTRIKLNQLLEDEYFLSIKVCINEHTGETLDVPPHAHISDDNNIKNKGIFANHLHHHHKTIFSQEIDKWPSDIIEPPNNNPCHVEEVCGKKVKSLGMGSSAKVYLYEKHKKKYAVKKIRHFKEEKELVKKFTDEFCISSCFDHINVIKTFFLLKDKHGRYNVVMEYCEGDSLYHLLHVQGGDIPFECVNCYFKQLVSGVSFLHEAGVSHRDLKPANLLFYKKDFRLLKIADFGSSDVFHPPFTSAHKVKGLTGSGVYTAPEEYSQNEYDGPAVDIWSIGMIYFVMMQLKAPWKSIEDPNYALYINICYKFHDQKGIEHFDLFNKIQNDFSRSLIYKMLDPDPSTRIQMKDLIADKYFSAIKICINQQNGDALSNPPHDHSHANLPSKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6J0</accession>
    <name>A0AAD5U6J0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FPR1</name>
        <name evidence="8" type="ORF">HK099_003069</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 6"/>
    <dbReference type="EMBL" id="JADGJW010000207">
        <property type="protein sequence ID" value="KAJ3221813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6J0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="36"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="96" mass="10715" checksum="4120B133808A3A37" modified="2024-05-29" version="1">MNLSKTSLIHSRSFSSSLKRMGVEVGDKIFTLFKKDGYKFDSSRDRGTPFECKIGVGQVIRGWDEGVPQMSLGQQAKLNITYDYAYGERGYPGAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6K7</accession>
    <name>A0AAD5U6K7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytoplasmic tRNA 2-thiolation protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CTU2</name>
        <name evidence="3" type="ORF">HK099_005410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6K7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019407">
        <property type="entry name" value="CTU2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882:SF14">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10288">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="392" mass="43820" checksum="EA53264AE68A5564" modified="2024-05-29" version="1">MGLQKADLGEKNKVLIAYSGGPSSTLLLNLTQTFHESSSHKKFVDVEIINIDESSMDDRNIEVAKKISEVANKSNFNYTQLKLESILEGCSQEFKKHLLFDGENPNSTSLLASNEEVFKHYISSIQSKDSVQDSIKNIKLRLILQHAKDRNCGLIFFGDNSTRIACQSIAMASKGRGYSFPIDFSLSTSWYNGFVIIKPLKDILVKEIGIYNKLNNLDSFPFFDGLEKLFGNKVSIDKLTEDFIIGLDVEFPSTVSTIFKTITKATTSVNDTCLPCKNCLGPIKSNCDIWLASHSVTRLETITNPVEELEVRNIELCYIACLKSPTCFVSIWIIHFTVLEAIEVSALTEKEDDLLPDTEFSCRASIKERSSTLESSVPINVLVQLQKLLTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6N5</accession>
    <name>A0AAD5U6N5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000200">
        <property type="protein sequence ID" value="KAJ3221941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6N5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="67" mass="7636" checksum="FC0D799070217130" modified="2024-05-29" version="1">MCSVFYTIVLKVPAIKFKDSVHITKDPNALSPYSMNSLLNDQLLSILPITELKIPKGKYKNRSRKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6T2</accession>
    <name>A0AAD5U6T2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004592</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6T2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="5">
        <location>
            <begin position="12"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="29504" checksum="DF462B0E6D9AF506" modified="2024-05-29" version="1">MQLHHILFSTNAKNSKGYTLVIRQQPLHCRVCGNGDKDHSNVDPPPILEIMEVDTKGKLYPVTQQNLFLTVRVSLWDEESKYQILNSKKTPGEKNILVGDLIKLSEVLNDDLNRTGSFFIFPRISIRSQGKYTFKFELINLEDKREPSTLMQYTFKKEVFIFSSTFIAFPPKYFPGATLSSKLSITFKEQGVKLTLKKSKGGNNNMLSKEAITTKKADSGVDLSLSESKSKVEGFKKMVAPSDNRMTRKGFKLFRKYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U704</accession>
    <name>A0AAD5U704_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein transport protein Sec61 subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SEC61BETA</name>
        <name evidence="12" type="ORF">HK099_002437</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000180">
        <property type="protein sequence ID" value="KAJ3222335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U704"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006398">
        <property type="entry name" value="Sec61_beta_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="72" mass="7695" checksum="9FC1571FC589C6C7" modified="2024-05-29" version="1">MNTASSLRKRNAKSSESAKNANKNGSSATMMKMYSQDDTPGIQVDPVSVLVGSLTFIASVFILHIVGKYTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U769</accession>
    <name>A0AAD5U769_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000132">
        <property type="protein sequence ID" value="KAJ3223389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U769"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF6">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="107"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="190"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="351"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="446"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="491"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="507"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="524"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="566"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="577" mass="64031" checksum="50EB032915796A36" modified="2024-05-29" version="1">MATFEVDYGDIDGDGDIDQELDIYGDVYKDEEEPEAPVSGEVNNSNSYQQQFDQQQPPPKNDLSQDDSAANSNLPANTDAGILDPNKNDHGFVTKKNYLLLKERYLSELFCSLLDLVRAVNVNYIERKFGVVIDCVIMRDQATGRSRGFGFLTFAESKSIDAIVKQDHYLDGKMIDPKRAVPKLEQEKTEKIFVGGVSPEVNEEEFSDYFSQFGGVIDATLMMDRDTGRPRGFGFITFESSECVDRVLTRQGSLYIKDKLVEVKRAQPKGGRQGFQNQAPIVPAAPLINPMMMGMGGMGMMGNMGGMGNLGGLMGGIGGMGGMMGMMGGMGRGMGRGMGMGMGPAGFNPNFNNNFNNSNPMNNNLNNNVEDNNDDDNKDGDDKSPRNRGMMPNQMVGGYNRQQQMFGNFNRGFNPGGFNGGYMNPQMNMMRQNMMMNMGRNQGGYGQGNFGGPGNFNPNGFNNAGFNNNQGNFNNNNNNEESFVDSEEADTDNKRKPFDKDRDSSAKRRRSRDRSRNRSRSRSRSRDRDSKRNRDRDRSSRGKDGSSSKRDGEGSDDRGSNERRGAGRSRHHPYSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7U0</accession>
    <name>A0AAD5U7U0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Platinum sensitivity protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PSY2_1</name>
        <name evidence="4" type="ORF">HK099_001123</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7U0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072542">
        <property type="term" value="F:protein phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006887">
        <property type="entry name" value="P4R3-like_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051137">
        <property type="entry name" value="PP4R3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318">
        <property type="entry name" value="ATP SYNTHASE GAMMA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04802">
        <property type="entry name" value="PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central" evidence="3">
        <location>
            <begin position="2"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="146" mass="16771" checksum="969FFC68BB438E42" modified="2024-05-29" version="1">MNQYEIVSYIQENEEFLKNLFSIWTDQNKSEESKNDVVLFLRGYCSIAKGLQFAHRTPFYRSLNNSQLAIRIAATAVLSNVLEHDPSLVRSYTLAQIRQSQPNLIFQVIERLHDEPDAGVRSQYSEILRILIDGPKNDGVIEVISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U854</accession>
    <name>A0AAD5U854_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U854"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="98" mass="11078" checksum="582837A2F0643F45" modified="2024-05-29" version="1">MEFKQPNETIPKGLIPDCAQKINYLPEESIPELDLELKNMSFSGLENVKEVELSIAATVASDLNNIDIAADDINSDEIDVECDREFLMDLDSQSYRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U885</accession>
    <name>A0AAD5U885_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U885"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="229" mass="27306" checksum="398AE2CBA2BD9C92" modified="2024-05-29" version="1">MNRSYHRQNTITEEERAAEPREFFHENFLRGRADLLKLIERKLPNQAYLKMQKKLEVNKGKNFSPKTIASITPQASFNSLNFNNDVDFKEEEELSIKDLVSLNKSLEYRVNYLEDKIEEINEKLYRKLKNENYNRFGEERHNESYYARSNSENKFKNQKKIVLNEYNIDEMKEQTVERAVGEVESPAKEYQVNKTLPYYRHRDDTILTAETLTKSYKTSRFDFGGWGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U893</accession>
    <name>A0AAD5U893_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MMS19</name>
        <name evidence="8" type="ORF">HK099_006705</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U893"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024687">
        <property type="entry name" value="MMS19_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12460">
        <property type="entry name" value="MMS19_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="MMS19 N-terminal" evidence="7">
        <location>
            <begin position="45"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="MMS19 C-terminal" evidence="6">
        <location>
            <begin position="471"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3228080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="965" mass="108227" checksum="E10462504DF7F44F" modified="2024-05-29" version="1">MNEENVTSLVKKFFNLTTESTDSIEIIDQITIAINNGTINFLRLVNSLEPSLTSQDPFVRSKGLGLLSSVIEKTDALSKAEGKVLLSYFLEKLYDQPSVAEILKGIREILKHTVVEQNQMLDILKSIFAELSVQSFQQSVRLLVYEIFEIILVENANFIKMNMNDDFIFECVSASPLFSPYALPLLLEKISSTSIGAKMDAIDAFIACLKVYDASDLIPHIEELWVHLKDSIFNSTNDDCEQLALAALKSISAALSTVPVIKQEDSSKKFLNLILTECLKNLTLPESILAKQSGKVLASVARASEPTCNYVCAEVVPKLLTDFSDIRVVTGKKNSLQVLVDLVESARLIYGSVNNDEQEDTFNPILPYKDRLFELFGKSLSDNYIPLNIVAIMGLSEFLLTSQLLGGPEMQQEGDNEELEDVESTALEALVKFGIHRPEILLEITIPDLFEILPEKLTDFENAILTFDNIINALEKISEISVLFEIIVSKLMEKLIRLNESKINEASASTEETERKLENYYLRILDSIYKSVQKFSYNISNEAEVNAIKSVSNSLFLRLINLSGIQNDKNTFDNIKVIRKTAKLLIELNAHLERNVRDEIVNTSFDHFTNQDSNSSFFVHFNVNTTSDTSLVLAAAVAACPPDQNLPMDAKSLVQKLFQLNLRTKNTTLNLSIAILISNFVNKNINCLDLLLLKDLENIIFCSSQEFFKRKNCLTVYTWVAKGLVISSNNLGYEIVDNLIRLLNISSNDDDIKISVLASHSFSSILVDDETGFLTKKSRAFVKSVYRQKFFKFVKGPLLNGFKDSKGSEVSMCNFLTSISNVIQKIPRSLLLKELPSLFPVLLSCLNYPDGELKLSTLRILKQISTSSKEFFEDHIGTIVPLLLDLSSFKNISIGNTMLVRVLSLDILGDLTNSISFPVVFPYKPLVLKTLKDTKGSYIDDPKKLVRKSAVNTRNKWFLFTGPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8N7</accession>
    <name>A0AAD5U8N7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005412</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8N7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051508">
        <property type="entry name" value="Mito_Carrier_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928:SF1">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="28"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="135"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3226186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="39357" checksum="4FBC5618F3EDF665" modified="2024-05-29" version="1">MASSLTGQVDPLSQYQNLFPKTGKPRTIGNLDSFIISALSPAGAVVFTNPFDTAKVRLQLQIKPNKKDVGNVNNNQIVYKNSLDTIQKIYKNEGLKGLQKGLIPAILRESSKNFFRIGMYDPIMGIIHDSKTGSAPAWKRLVAGSMCGVMGAFSCNPFELVKTRLQSASAGKITVGHQHNYTGTWHALKCIVRDEGFFKGLYRGSVLSMCRSVVGSGTNLANNDERIFNAQSRLARFENFRYRVWARISHVVRTRYYNQPYDSNSKGKLYSSGFDAITKIAKAEGPTAFYKGLCLYYFLGILRRQLNEYYGYLDRKDSFLFFDANNDGALNLSECENLLNGVFFNDKEKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8U3</accession>
    <name>A0AAD5U8U3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA repair protein rad2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAD2</name>
        <name evidence="6" type="ORF">HK099_007902</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09868">
        <property type="entry name" value="PIN_XPG_RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171:SF7">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="5">
        <location>
            <begin position="619"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="4">
        <location>
            <begin position="1628"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="264"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1886"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1889"/>
            <end position="1902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1908" mass="217656" checksum="8FE5D8C627BB61BB" modified="2024-05-29" version="1">MVHYYGMIAFKLANLGNGVTVSQIPVTSGGNVKIYVSNNYANMKTITVINKNYASSGPFVTNIKVDANKFKFATSVVLSAAGGVKDVVGPFSISGITFSSVTGLAQGVSQEKRLKVDQGIVSVSVDAETAMIIRLTDVEVNILDDILKVEDVSLVPKNEDGSPALSRGFINQYLTYLTIVMGLIADLQKIITQIVHPKTFNFHKSRSIMSQVNHATETQNIHQNLMMYTKTDETATSKNEVYYPVSAFPLILKAEPKSNQKLAFERDSTPIKRVTTPKPVHSPKSSPKLFGRGSTPKKDRKFNEGEVVFIQKDDTSQIKTIGMIIPKEEYDDSMPLNEVNAGQFLIRIFGEFSYIITEEKNLSSFNPQKHNQESTQAAVVYLKSGQIDEAFKWNKWGKSKKYRSVIQGTEATIQRSPTPKANKLKVKTKKKHSVESLEPYTENSDAPLSAVYSKSIDDEIPLLQRFSQSTEKSEKEFEKEKEEILPENPKTPIDVTKLFPKCLLENNELKSVKERKLIFNKIKIKFEEGKEIFLNLEKLIKQHCKKQSPTNGTTASEELRMVVDEALKIRINIESSIQKEFGTDFFFDLNQPAVFNSSSKKRNNEGLSLEAPRKSSRRKMSLVTPVGKKTQLEHLAGKTLAIDSSIWLHHFLKATPNLRRICKLLFYNIKPVFVFDGQTPLIKKKTTAERRKRKHNSERNLEKAAESLLEARIKKFLLEKDSSDTLNATDNEDMTISTSIDAVENMFVNPNNKTPVSPIKQKKDEYELPDVEVRAHSNNDPHLPSHWELKNFIEDYKDSNDFDDKNFQNLPVEQQMEVILDLKLKSRLGDWKTLYKMQKSDVTAKDFSYLQIENLVYRNKMTEKYADFKINANVVVNPLAHKHKDKPTDRIETGRIAGERGAKRYMLIKNDEGDSKLGGWKMRLETNGEVSVDTKKSEVKEIVDLDDYDTLGRNISSKGIYERTTDILDSLSKSKKKHVSAIVLSSDDEIDDVEFVEVSKEKKDDDDDLLFMDQRKGDLHEFTKSEPSAVKFHGESTLFVSDDEDIETTMARFEKLENQKVNINEKEVPESFFSDNINNNKTENFLLTLSPEDFLFNWMNSIPKSFKLKFNEVGYDWESIVKEVFERFDVKRINNETKFIKKKISKLSLNNLYEQNMEWMNFFKMFLESVKNWRSTRLLQVDNENCEVSDDEEFISITEKNVFVPSAVPSPTTEILNENGNTRSNKITDLIYFEDDRYIIIIPNVSIYNFILSSDVEDENELTNSRNDKEILADSSFSLNNVNNSMQPVDLKERLTQTKENLTEFEVSSTCENKIKHSERSIDVEAEFEESKFFKNRGVELKDNSILANADEINEIEIQWKKQSDVPFNSNETDLVNSKLFALVEDNPSSFMQCKDTHFVSEIIPIASQAIAENDKLFKVDSNISKCKKTSPYFNKNLKMSSEIENKIHLEKQNDRLKGNQDIGFDISDGPLEISPLQKKRKLNTTEIQNILTSNSQNANNDLLQNSSVLQQNLEFDDNGSLICSSSDTESVEDEALTKEGGSAPMDLEELNFTNEVISIIENSNVSAMNDDKEKGEFDSFFNSQNFNRSKEEIDAEINRLTLKRDKYQRDSSDVSSDMIRESKELLELFGIPYITAAAEAESQCAFLNENGLVNGIVTDDSDVFLFGSKNLNVYKNLFNQNQFVLSFNSDDLQKEMNLNRKKFVNLALLLGSDYTEGIKGVGAISAMEILDLFPGEDYWKEVKAGTDKKLCKRIVVPNHFPESIVMEAYMNPIVDTSLQKFQWYRMTNVFSTEIFRGEPNLEGLRDFFEEKLGWENAKLDKILLPILRKRGSLNKTRQTTLENFGFKNNGLTIEKIKSNRLKKTLEKKKKVDLIDLQEDNIIATRGGKSGRGRGRGRGRGKKVAELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9I0</accession>
    <name>A0AAD5U9I0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000071">
        <property type="protein sequence ID" value="KAJ3225106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9I0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="275" mass="31381" checksum="7F33B17519134E6E" modified="2024-05-29" version="1">MDIHATEGKQVCKWRKINKGGASCNIKCRHKGYFADHAASHFSFQLRPIKCKYCTNHFRNRQERRRHEGSCAERSNSNYQVKPNSGFDTNLLVTNFAPKNQNHFNESSSRNENSFYDNQFTTSNSANYRSIMRNDPSQIKNNDDNFLQTADVNKYPVSDQNNAYVLLYNQNSTNSHEQQIKSHEQQNLYENSAIPTSRQQDGDKPNQLSDDSFCLNKNLSNESFFLNQKNSFCEKLGTVGTKVILNVLSNNVQKQQALDNAASRLAASAEEVEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9J5</accession>
    <name>A0AAD5U9J5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002892</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="749"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="761"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3228387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1558" mass="175736" checksum="87CE8FC8A6419E34" modified="2024-05-29" version="1">MITPINGTYQRLLGIVSYCKANEGTQSTVSTTADFNYITMDYNDLNYIYTILDQSEQILMDSGKLETSESIKVDSDPSFFSYFWSGTKTTNTSSTQSVKGEIKYMLKFIEQLTALKLLNTSTEHIKELETLPQTKLKLKPLLNLKGLELNNFRLSNLSDLLETGFRLKKLIIKNHPFFEDEVKELLKKNFSTANDTQEKKEFSIIFPNLSHLSLNNLDLKSLPENLLENCSQLVQLNLQDNKLDSIPIKSLAALSSLHDLNLKKNDISTLKDLKLYKLSSQERLGDTDIKIPVIYTENHVVNRVLVNLVRLNLSKNYLENLEGIENLNNLKFLDISENGVWDVWEVGRLAVLEHIQEVSVKGNPLTKLENYRVNIFTYFKSKAFSLSLDGVSPTSSEYRSIRSNFIIESSSVPTDSTFYSTSPNSSTATADVRVKGKKKKHSHKKAVKRVVIKSSEEEGVSSNNNDISSTLLTENSESAKSCKELINEKDFANSANFSSPALDQRKISTTSTTNPSVSILGEVLRRKFESMKDDNGSNWIQVYSDTLGILKPHATNDTVPEEQLMIPSSSSVEKVNLDDEEVLQSDDTKNIVGYVENKKEDTLIVDDKSRIFNNTIMPAKRDSEKVTVESELENTSSLTKDKLINGNVTSKTTENSNVVLLPKSSNVGSISQIGPGYRKLFEFGPRKDESSPQIKFNPTFTAKNSGNFSSRIETGSLKEFTGLGKIKEDKIFNLPPLVVLAENKYQKEGEKLPSPPFAYGSQGTLGNGSNQSGSVSTPPLILSRPVSSSVKYTKSNFGGSSKNGYSVAHSYSSFHPTTQYGGGSFYSAEAANHAQQRNEQYLLPRSPSIPFLKMTNSLQLHLNFNVFESDKEKILSWIPGSYVKQLPTNLRDGPNGSFGVTCDSKTVKAVEMRSKSKLSWLLSTLCKTQDSKWLIDKRSSNLISSLIVNSNTESNANSFLAIEKLKYLVPIEKPSYFLLTNFKLYIFVPKFSFPYHSDEFNDPYAQFVNNSMQQVRYEDPSKSISLKYIIPLLKIVRIDVGPNYQYLVIHFWKNKDKGTKSSGNENTLHSVENHLPFHSLTLVTRDKIATLKFLKEISHFLHNADNNSIENDSITCNDENTTCSKFSTLKHHNSKININFDWYINSLQEEIYYSSLKKLKKNENVKFYEWFLKNNVVFNSKLDFKSIGIDEMHLTSNRISNIKGGWFGLFNVPFSSSTNDKFNSKKDSVVETPNLLFVSEDEKIDEEKPSIGIEDESLELYLHVGWVVALEENLTNTSPLIRTTALIATNEYLYLVLERLDVWPPLYFPPESSTSANSSNSVLNLSCSQEELNQISSKGLVADLISPFAHYRESSSVLSFGRVKDIVKVERWRSWRWTPLSEVKQIGVEASNEACVMQNGCIGICPTWKSKSGSSTENKHRDISDSSISINRRAADKNSFRKRNLDESIGTGNAAGWSWWIRIYLRQQITPDTAIQSDLLWWDLLFVNLDAADEFITYLRRVRKINSDSQDMQNFTDSDALLDYKDSKGLIDTKIPNHGDISNLEIKECGVDLIIGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9T7</accession>
    <name>A0AAD5U9T7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c oxidase subunit 6A1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COX6A1</name>
        <name evidence="8" type="ORF">HK099_004407</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome c oxidase subunit 6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9T7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.95.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001349">
        <property type="entry name" value="Cyt_c_oxidase_su6a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036418">
        <property type="entry name" value="Cyt_c_oxidase_su6a_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE VIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02046">
        <property type="entry name" value="COX6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81411">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3226663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="122" mass="14239" checksum="1B75560B0034ACDE" modified="2024-05-29" version="1">MQRLSLNLRKIGRRFASTEATSTSKFPPLEKMMTKEAYEARHHALGTISFWKKFNYFITLPGLILVALYALPQEFAHIKHLQEHPNELVPFNYLRKRKIPWGDGDHSLFCNPMCNPDPKPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA55</accession>
    <name>A0AAD5UA55_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003859</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA55"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="8">
        <location>
            <begin position="67"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="415" mass="48020" checksum="4FE1A67D243A81B7" modified="2024-05-29" version="1">MNVSLELITRAMDKNTTITRFSIQRLTSMRPNIVKTFEPCKGRTADAQINVKIDILEKFFQIQVKVVQRQFVILNDNTYQNSIKWSKSETSFIVINSNIFANEVLPLIFKHSNFISFVRQLNLYNFHKVNRAYHRQNTITDEQRAAEPREFSHEKFIKNRPELLSQIQRKIGPSLKRRSSKVLSIQTNPGTDSSFNGFESSNSSTKCNSEENLFSDISGDNPTKTDIFFKAVLNSKEKNSLMSPLTMRSDSDESAIYRCEESKLTQKRLDYSFPFPRLQTPTTPDSLNESINWTPKNKYYQHNLKKEDYELTLNTSSRTNSDTKLNFKEFYSLPPENNEGIEIYNQKDGMRLVEGEVTEKIEKNKVLKEYISVFSEKAAPNKDNAENNNKLTLFTVNALLSTEKPNGNPLQRYCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC23</accession>
    <name>A0AAD5UC23_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_004299</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC23"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049080">
        <property type="entry name" value="MOV-10-like_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45418">
        <property type="entry name" value="CANCER/TESTIS ANTIGEN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45418:SF1">
        <property type="entry name" value="CANCER_TESTIS ANTIGEN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21634">
        <property type="entry name" value="MOV-10_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase MOV-10-like beta-barrel" evidence="12">
        <location>
            <begin position="173"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="10">
        <location>
            <begin position="296"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="11">
        <location>
            <begin position="569"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="11">
        <location>
            <begin position="681"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF21634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3228306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="868" mass="100032" checksum="B247A0B7DE5FB80D" modified="2024-05-29" version="1">MSYTYSNGWDKSELIIDDIQFNLDMQKRKRKEFRANFTMNKVIFLQRSLNFDIEEDFAETRKLETFKLVSPHINFSWDNKIIRGRPPDRPSFKNLIYELPQYPFIYDPLIESKFKAFFDGTGYFSEKLNSINFIEYFKELLLLEERQMIVDIENYTKAININELIRIPISNSRSDCFYKIECPGVADDRPNVNYGDKIFVVHANQTYSGYVWKVESAAVLVKFTDNFKTLIQNSEEKTAILKFKFSRTSLRYAHRGLDLLGFCGTENFRNWCFPVNTTNFDANNSEFTNIALHSKKLNAEQKKAVTRIVFNLHGSTPHIIFGPPGTGKTLTLVESIKIMHLFNKHCRILVLAPSVNAADLLLERLTSHALDKKPSFTKENIIRIHSHTRLKKDIPKDILKYSYNINDKLYCEIPPLKELKRFNVIVCTLFCAAFLRSTGLFDVEQISGQFSRPFTHVFFDEAGQASEAEVWAAISGFFSPFFTKKESLSEDKKAEFDKICKEVPKTDKEKIKLLPNLIIAGDPNQLGPEAHFNTGDQGLARSYLARIVTTCEAYKEKKATDHSEAYENPQNITKLLRNYRSDLKILDLFNKKFYNAVLKSEKTSFLNFSKLGWLPSTSDNYPVIFHNVDGIDQQQTNSPSWFNTAEIQIVINYVKCLLFGSECPVPVNEQSRNKTKIRSVLKKRKEYETSIFKQGMAAIKSSQEEVVRSLDSSQIGIIAPYRNQLERIRTVLNASGLGDIKSGLISDFQGDEREVIILSCVRATSYVGLDYNNGFLRDSKKFNVAISRAKSLLVVVGKIDRLIEDENWKYLFDECLKNDAVVNYHKVGNKANKKRKVEFKEDLYTDLDYLSKSALMSQQREVKFKSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS95</accession>
    <name>A0AAD5XS95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">CDC5 cell division cycle 5-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CDC5L</name>
        <name evidence="16" type="ORF">HK099_001749</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001524">
        <property type="protein sequence ID" value="KAJ3202761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS95"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000021">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000091">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="16" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="15">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="14">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="14">
        <location>
            <begin position="51"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="15">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="103"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="414"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="737"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3202761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="775" mass="88491" checksum="4BCE880B05F59680" modified="2024-05-29" version="1" fragment="single">LVKGGVWKNTEDEILKAAVMKYGKNQWARISSLLVRKTPKQCKSRWYEWLDPSIRKTEWSQEEDEKLLHLAKLMPTQWRTIAPIVGRTPAQCLARYQKLLDEAEDKDNEEEGLTAEDVRKLRPGEIDPDPETKPARPDPVDMDEDEKEMLSEARARLANTQGKKAKRKAREKQLEEARRLATLQKRRELKAAGIDSPLYQKKKKKKKGLGMDYNADIPFYAKAPEGFWNTVEEKEKEDSEHKNMDNILLQKLEGKRKGEDEAELRKKDAKRQKRKKESGEYVSAQALKEAQEQERKISDRKKMILPAPLISADEMEVVVKLGLEGENIKQLVDAGDKTTGALLNDYSNLRSATPLRTPKVAAGEDSTRLMAKNLLAMTNAQTPLLGGDLETEGEIEFNGITPVRQVAHTPNPLAAHLTPRGNQSNFSATPKGKKGETPVRTPLRDGLGINTPMGSGFEETPRGSRQSVIRQQLSSLFARLPAPQNDFEIVLPEQENTEVVEKSKFTEDEADVQARIAAEKLKMQRERMEKRSQAVQRDLPRPTVIRAGCFALEGLDDVQKLITEEMHALIKHDAKYFPVAGQYPFTQTVELEDFSLELLNKASLLVKKEFENENKLIDTEKNLNEFCKLYKTYHDKYTFVPGNGKEFGTFMEDSKISEEQRVDIMKNKFEANKELMRKEAQKAAKLEKVLSVKLGGYQARSSKLKKDLAVTVTELESSLIELYSFQELKIRVEDPGLEERLLLLEKEVKDLEKLNNQTQQEYLELYNEKRNLLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUP5</accession>
    <name>A0AAD5XUP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alkylated DNA repair protein alkB 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ALKBH8_1</name>
        <name evidence="4" type="ORF">HK099_005830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000473">
        <property type="protein sequence ID" value="KAJ3216553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUP5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="3">
        <location>
            <begin position="67"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="30169" checksum="E9414DA4414CCAD7" modified="2024-05-29" version="1">MSSASSGEISKNLDPNDLNHLAVEKEEEYVHKVYDAIAPHFSLTRYKPWPVVDDFLNHLSKGSFGTDVGCGNGKYISVNKDIFILGNDRSKNLIEICEKKGFEVLVGDACNLPYRDSIFDFALSIAVIHHFSTSDRRRNAIIELLRIVKKKGKILIFCWAFEQTKLSKRKFLEQDQFVTWKIPKENQQLSIEDSKLQNHSFVSKKLKEMDINNQTGEICYKRYYHLFKEGELESLCEGLDCKIFKNGYDKDNWWVILEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV01</accession>
    <name>A0AAD5XV01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005423</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000420">
        <property type="protein sequence ID" value="KAJ3217589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV01"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000001">
        <property type="entry name" value="Dicarboxylate MFS transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43045:SF7">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43045">
        <property type="entry name" value="SHIKIMATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="21"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3217589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="467" mass="52251" checksum="9ACDC70A38837849" modified="2024-05-29" version="1">MLNTERTTLNLPEMEVNIKKVIFISAVGTLIEWYDFFVFGTLGTVVAPQFYDKSTGFGAIIYWLATFAVGFVVRPIGAIVFGIIGDRFGRKITFLTTLIIMGTCTFLVGCLPTYNQVGDAAGALLIVLRILQGLAIGGEYGGATTYIAEHAPPHRRGFYTSFIQVTATLGLLLALIIVLIVSTITGTVKFSEYGWRIPFLFSILLLGISLYIRLSLKETPMFKNLKNNGNISKNPFMESFGKWQNAKIVLLSFFGATMGQGAVWYTAQFYSLYYLQTIFHTPDTSSFIIMGVALLLAAPFYVLFGYLSDKYGRKLFMLLGLALSCILWYPIYMGMHHFRYNETATWEKIESTSIVMFVTLVYGPIAAYLVELFPTSIRYTSLSLPYHVGNGIIGGFVPVVGLWAIQLTGNNFAGLWYPLVCAGTTFLVMLFVSPETYKYDLYETPEDQRDQNLKDEGLVRYDTQDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVD1</accession>
    <name>A0AAD5XVD1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001184">
        <property type="protein sequence ID" value="KAJ3205706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVD1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="13"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3205706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="139" mass="15919" checksum="FA3E5C0EE2864975" modified="2024-05-29" version="1">MLSINSNCCIVKSKTSDTKSETASVSTTTTSTNSHPIESTIPQLERLDTSPNYESHSDTFVESNEVVDQKAIIEDENTVEIPLQEEIGLKEKDVDLLDEEEEENILQEKEEIEDENEIEKKELKKEENLNKIEEDKEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVH3</accession>
    <name>A0AAD5XVH3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001861">
        <property type="protein sequence ID" value="KAJ3200646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVH3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="102" mass="11280" checksum="ACD5FB493051E1F4" modified="2024-05-29" version="1">MISNATKALALSITSGVTIYTLCNLTPIQKSHSNLELRNVNSAASLGLVGCAALGYNALTNQPQKKQNGLGVREVRWLNHDSSDSQYLKERKWARDFCNPRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVL9</accession>
    <name>A0AAD5XVL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">K(+)/H(+) antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">KHA1_2</name>
        <name evidence="9" type="ORF">HK099_004462</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000316">
        <property type="protein sequence ID" value="KAJ3220051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVL9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="8">
        <location>
            <begin position="34"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3220051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="777" mass="85360" checksum="FAACE9AC6A1C4290" modified="2024-05-29" version="1">MAPTVSSFLSGANPLDNPLSLLIIQIVTIVSFSRVIAVGLKFFKQPLVIAEVIGGILLGKSALGRIPGFSQTLFPESSLSGLNLIANVGLVFYLFLVGLELDAVGMFKSFKKSAFISLSGVVIPFCLGLGTSVLLFRYLMPQPSNVPFISFLIFIGVATSITAFPVLARILTERNLLGTVVGQAAISSAAVDDILAWILLLIVVAMINNTGHYVTALYAFLCIVGWGLFLILGVRPIFHKFIAAAEKNETISEFTLVVTFLLVLISAWFTEAVGVHAIFGAFLIGLITPHENGFAIKVAEKVEDFVCCLLLPLYFAYSGINTRIDQLNSAISWAMVGLVMLTVMTGKIGGCFLASKISGYSNREALSIGVLMNTKGLVELIVLNIGLKAGVINVEVFTIMVVMALLTTFMTVPVISLIYPTKYHRANLLQKNIEGVRSITESDKLEIQELSSLPDLEREEAKLNVLFPIIISKDTNFIIPIFQMISSSVAVEVTALRLIDIETRPSSIMKMQGSHSIEKDHSLNLFKFATKFSLSTLEMMLRITGKENFVDNIIEASARNNSNIVILSHGLDSEEISFGAQNKFFNDLFNQARCTIGILVYNKSEDINDAYEASLSTVRSINSVIMKSSSNHPSGILYVLFNGGADSREAVRFALICSMKEGGTMKILIAKDSGKDSNSKIIEIERQDTIQNDQIFFQDEKSKDTEFLESLQNHTNKKTGEYMIEEVENLNFEEVLKSKNIKKSDLLIVGKNYFFNTHNFPSKVFTPCSIFVINSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW92</accession>
    <name>A0AAD5XW92_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000947</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001241">
        <property type="protein sequence ID" value="KAJ3205032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW92"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3205032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="282" mass="32539" checksum="6CF918099CDBC130" modified="2024-05-29" version="1" fragment="single">MENFSVLPDTPSDDEFDDFALQPNLSYFQPQLQYYEEQSPLNKVQSFQNIPFQQQQNLFFVHNNNGINNPNLVNKPSNDFNFYNLLNQQKPLTSLQHQQQQQQNFQKILPTVVVQKKREPLFKEGFNSSNPPGLLTAQELNKSIVPERFPCTRSQYCTKVYKNANGLKYHLIHGICEISDQEATKSTLISPIGTPEKIGMSINKSILPVQLDENGDDSPNTRHFKTFIEGVPESERRDKPYFCKVNLCGKRYKNENGVKYHVRAMHPNIDWKKICGHDSDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWF9</accession>
    <name>A0AAD5XWF9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleolar protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NOP2</name>
        <name evidence="13" type="ORF">HK099_007353</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000701">
        <property type="protein sequence ID" value="KAJ3213531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWF9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009383">
        <property type="term" value="F:rRNA (cytosine-C5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1170:FF:000001">
        <property type="entry name" value="Ribosomal RNA methyltransferase Nop2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011023">
        <property type="entry name" value="Nop2p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023273">
        <property type="entry name" value="RCMT_NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00446">
        <property type="entry name" value="nop2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF30">
        <property type="entry name" value="28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02012">
        <property type="entry name" value="RCMTNOP2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="12">
        <location>
            <begin position="301"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="131"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="518"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="393"/>
            <end position="399"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00082314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3213531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="653" mass="74008" checksum="F784D616AF14D4A5" modified="2024-05-29" version="1">MAKLNHKQRKRQSLPADFSEPINGKPAKKNLNSKPKNKTKVKKTRLASNKIQKNQSKQIPSDEEDSDDHIKKDKRESLKDLERLGQFNDDDFELMSDEAGDYIDEEFDDNADESNMDNDIDNHNNKMKMFENSEEEGDIELNGAEEDSESFSEEHTETGNTESAEEENYSDVDSDGNELLEIEKESKKLDKKRKIDEVLAEEELQTQMQQREAFVLPQQELDDAEMEVEEEDAAEDLQIVQTRIQEVVRVLNRFQELRDEGRDRAEYIAQLKKDLALYYGYNDYLLNLLFDLFPVSEAIEFFEANEVPRPVVIRANTLKAGRKDVANSLINRGVNLEPVGKWSKVGLQIFDSPVPIGATPEYLAGHYMLQAASSFMPVMSLAPKENEKILDMCAAPGGKTTFLAALMKNTGSIFANDANKDRCKSLVANCYRMGVKNCVVSHYDGRQFPSVMGGFDRILLDAPCSGTGVISKDPSVKISKSEEDFRLLTHIQKELIISAIDSCDAKSKTGGYIVYSTCSVTVEENEEVVNYALKKRPNCKLVDSGLDFGKDGFSSFKGKSFHKSLNLTKRFYPHTHNMDGFYVAKIKKISNTFKKVDNDEEGVIIGNGSGYMTSTNKKQKKLMKNEKLVEQEEVKFNDDEDEKIIKRGLKKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWI8</accession>
    <name>A0AAD5XWI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_003033</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000205">
        <property type="protein sequence ID" value="KAJ3221849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000335">
        <property type="entry name" value="ATP binding cassette subfamily A member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="291"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="876"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1232"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1276"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1313"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1343"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1371"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1402"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="477"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1482"/>
            <end position="1713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1848" mass="208332" checksum="4DA13D607EF7A0BF" modified="2024-05-29" version="1">MIIKNQLWKNQFNTLLGKCFRLLSQKPKFILFVVLFPILAPLLSIYLPNGPVYDTTLNSESYVKSVELTFQSQSTLFYFAPNDKKHLDIMKTFSLEQGLDFNKNVKGFSNYNDMISSIIENYDHVKVQDIFRAVDFQSENLNFNQTRYNLWKYEYNARSKEYSNLFSDAKVELGLNQAIILTLKGSNVTARSNLNSKVNWVLPVEKPLYIDNEIRREYDNVTRSLDWKLKSSKGEKSVYVVPIYSFRNPMLTIFFPLVFTPLFILAFAIVEEEKSSKIFETINRMGLYGSAYWLSHALSLLPIAFLASVTFSLSSFVVTVLFPQTFLAQVNIGVVFLIGFSCALSFLSLGLLFGSYIDGEGAKVVFIILVIGMFLTTVPNELNDNIISQFGWSQFLNVANLPALPSHIAQKYPTYAQSRNSNPPTLTFIFYNIIIAILYIFFANCVSHGFNYKVLVNKFKTSKTAEVEVVEEDINGIEIKNLTKFYNVSAFTTEVAGSPAVDNLSLNLKEGVVYGLLGHNGSGKTTTLSILSGKIKQTSGTAKIFGYDVKKDMQKIGMIMGVCPQTDILFENLTALQNVTFFAKFRGVKLNPGQTYEDYAKNKLNDVQLLGSANKMVYGFSGGMKRRLSLIISTIGDNLKVLFLDEPTTGLDPLSCRRVWDLIKSIAKDKIIVLTTHSMEEANYLCEVITILEHGKTRATGTPSALKSIYGKGYQISLVDSNLDRKDENSLKKLALSYIPDCSILSDSTFALTIGVSKNDNDQLKSFLTMLQGQSRIKWSISNSTLEEVFLTLAPESITNTSDEDITEVDTIGNVSKDNSSSKHTLEVDENNSVIEVNDTKVKSDIGSKNRFLNQLKGIFAKNIILSGFHVRRVRVYMVFFWIFLNIFVATPYNIIMNVVFDDKDCLINFRCGYQLPPADIQGCDIFYKNDDYGPDYMCGKENYLARIRNISTEVEEDIVDDWKKSGFTYYRQPGGSPDQGYPFKFAGYIDPLEPGYSVNLETQIEEPGLFDSDGASEFLASQKILYADSQLEGDLKFADLFSQQNYNFEAANGREIENVLRSKLSTLTSKKVIPIAGNPCAINGETPYFTEYTEFWKNLQETYPKHALKFNELNNSTGRFSVDFFLYATKNLRGDKSYPHVYINDPSNQYICLSAGKHFNNKLNISPFVNAVSNGVLKRMLGYNSTDVKAYEEAYLNSSVVTTDPFIHSQVKKFPLIFTSENEVKLNDYGFIWLMIMIFLSTTWTFPQFFYILVLEKRNFRDLFRIQSLSPINYWLINFLYGFGYILANCLSTCIILILSLLPPYVVLDLNIWIIIPAYINWAYAVTCFSIFYAATFNKNSVTIFIVFVLFVFKIIGAVSIQRFVSGLPIIYLSLIPPISFMSALKISYTSGSFKEASLHMLMGFLGSTFLLITGLYLHLTQPSKLGFVYFKPFSNLFKSKSRTLNKNGGEATDVIIDSDVLEEKNFVAKSLGKIDETSAIKIANLRKSYGKKVIISDLSINFKFGETFGLLGPNGAGKSTMISCFTGLTDYNEGTIEFAGNTIKNSKNLQELVGFCPQFDTLYSSLTIEEHIMFYGRIRGIDENHLAAKCKEVAMELGLYRDHYKKLSSNLSGGMQRRLSIAIALISSPKILVLDEPSAGLDPATKRSLWAVIDKLGDGEKRSIILTTHSMEEADALSSRVGILVNGELKALGNQIHLKEKFGSGLKLSLQVEIKLVKDKNTFKEEELNNLEKEKLAIIDTEVQKKISPKSKRITNNLKNDVLENLKKQFNVNLEKYEGLNIGEVFAWTAEVEYLIPKEEDVSKIFVNLESELSTLGVVDWALNESTLEDVFVEVVNPTKNLTLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWV6</accession>
    <name>A0AAD5XWV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="8">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001705</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010001509">
        <property type="protein sequence ID" value="KAJ3202878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWV6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF6">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3202878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="43681" checksum="16327AF3DE6501EB" modified="2024-05-29" version="1">MGMTKEFNDAKEYIENLGFEIYEIDKTIGIFENVIRLLGGLISAYDLSNEDIFLQHAIYLGNKMLPDFDTPTGLPVSWFNLKTGEKQLSKEYGAVYGFSYLADVGTNLMEFTRLSQISKDPKYEKAARKGFQSLKKAGKNMQIPYLYPMEISVDNGGGRNFQYTIGACTDSFYEYLLKMFLLTKDEDSRELFDLSLEQIKIHVLMKNKAGSYYVKDPGMDYNMHHLRNSKNVEFDAEVAQGITESCYLMYSKQKLGLSPEVASFNTGSNDENIVRPVDRAYKQRPEAIESFFYMWKLTKDEVWRDMAYELALNIEKHTKTAFGYSGIDDITMNPIQYDDIQDSYFLAETIKYLYLIFDDSNILDNWVLNTEAHPFRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWZ2</accession>
    <name>A0AAD5XWZ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PPH1</name>
        <name evidence="9" type="ORF">HK099_001476</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010001414">
        <property type="protein sequence ID" value="KAJ3203547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWZ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="8">
        <location>
            <begin position="113"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3203547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="308" mass="35326" checksum="3BAE109F9ADDC40E" modified="2024-05-29" version="1">MGLADVSDVDHWISVLLNCKQLTEADVKKLCEKAREILMEESNVQPVRCPVTVCGDIHGQFHDLMELFKIGGNSPNTNYLFMGDYVDRGYYSVETVTLLVALKVRYKERVTILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALIEEQIFCLHGGLSPSIDTLDHIRSLDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISEAFNHNNGLTLVARAHQLVMEGYNWSQEKNVVTIFSAPNYCYRCGNQAAIMEIDENLKYTFLQFDPAPRRGEPHVTRRTPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX67</accession>
    <name>A0AAD5XX67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH-ubiquinone oxidoreductase 21kDa subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006092</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000503">
        <property type="protein sequence ID" value="KAJ3216022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX67"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053229">
        <property type="entry name" value="NADH-Q_oxidrdct_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019721">
        <property type="entry name" value="NADH-UbQ_OxRdtase_su21_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34062:SF1">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 21KDA SUBUNIT N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34062">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10785">
        <property type="entry name" value="NADH-u_ox-rdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 21kDa subunit N-terminal" evidence="3">
        <location>
            <begin position="14"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="129" mass="15354" checksum="1CDBEA3A7E41EC38" modified="2024-05-29" version="1">MRFFSNLPDDEHVPFKFIAADPHVKDVVRYFRPSDYLHSTAVALGGPAIFYAWERYSPSFHPRVLPKILLVQFPFFAACGVLFAAQSTYFRFWGWTENDREVKKWEAESEMRRERDAGKEKWGWQDNDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXY3</accession>
    <name>A0AAD5XXY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside diphosphate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NME7</name>
        <name evidence="9" type="ORF">HK099_007859</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000080">
        <property type="protein sequence ID" value="KAJ3224815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXY3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04412">
        <property type="entry name" value="NDPk7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006602">
        <property type="entry name" value="DM10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057579">
        <property type="entry name" value="DM10_NDK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037993">
        <property type="entry name" value="NDPk7B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43109">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43109:SF2">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25364">
        <property type="entry name" value="PH_NDK7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00676">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51336">
        <property type="entry name" value="DM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DM10" evidence="8">
        <location>
            <begin position="288"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="657" mass="75455" checksum="6D501B6A1150395F" modified="2024-05-29" version="1">MDKNQEEKFPQSYVVNEQLPQNEDLFTGNYQQFGYGNLNDNVVNEEENYQYTHNFQHPQECVLVPPEHYQQEDFSPILTETYYKSDPVYEADNTPYQYQGQYYPSLSNYNNTNVQYTSEPCLDERNLGAATRLLKNSYPHNKRQPLDSRSSMLTYGQRQGMQNSNATIIPPYSLGVTLYFLYPRTPEIVVSKPYLNADLSGGSSVKVVGSPLTASVENPFVLTFFLFLDVAVNSKNLIDWDLNYIKVVGTVINPDGTEAKGLDGLGTVNNVKIKKLGVTNLTLQVIKPVDRYCFVVEWFDVHAQLTRQYNLYYCPEDSTVEMFDLKSRKTFLRRTRIEEDIKLSSFYLGSSLNLFSRQLQIVNFGDAFTRSKLEISNEKTFLVVKPNGYLQLGIILNEIFKNNNMSEFNLTGLKMLDFEEVFVRHLAFKKEEERFGEEFGNRCTVFRLNKANAVEELVSLVETSPVLSKLKNLFYVPKNPAEVKETLNLVFGQENSNGGMKRTSTLYKGNKDQRKYFQTLCLIKPHAVNKFEHGSIINEILKENYFISDMELFNLESANAEEFLEVYKDVVPEYHLMLDQLTSGILVALEISGKNENIVCEFRNFCGPSDPELGRLIRPQTLRSKFGTDKIKNSVHCTDLTDDGVLEAEYFFKILVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY09</accession>
    <name>A0AAD5XY09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY09"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="543" mass="63734" checksum="4E849E6EC2EA7382" modified="2024-05-29" version="1">MFSTKVNNSGNKRSKLKIFIFGSITLGISFIIARLYNKRHENLLELPETVLVHLKNLKNKESDELHYLNALEEVDAVLGDSSVERFKLVHQFYYFYLIHKKYDDAIKLLFLNWLKLLKIQNAEINNLHLVTSRYKDSVAQAKIESVSNSILKNSNSFIGMEKKETEVKSTYLDVINKLGYFNSFSCNLATTFWKINNIDAATLILEWNLRYLLGYPSNVLTLIERIESTFGDNKILNSEKLESINLLKSKNAFEKYLKKRNLNFFGYTKELQEKNLENFNTFRNKHFQYFFEHAPNFDVLISEERITALKNYFSEIRSKVKKEEDNFKVKDMLSRKDNLYKALRSEFIQYNFLPEKLNPIFKHFSVDFTNALNLVLHIKYLYDNLEDDCVLNVISIGQDLLQNDRVRFEEEREVQFLNNSKMNLKNEDKVYINKSNTSESNLRLLKSQILLNKCDFENALINLNEDLKFLNSLKVDDSAAKYLFSRKEYFSLIYLGVIYLAKGDKEKSLECFKKAKSITSTLNDLSLHKRCEGYIQDITNLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY35</accession>
    <name>A0AAD5XY35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dodecenoyl-CoA isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ECI1</name>
        <name evidence="3" type="ORF">HK099_006674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000592">
        <property type="protein sequence ID" value="KAJ3214788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY35"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF45">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="29193" checksum="8C3704D302E2A46E" modified="2024-05-29" version="1" fragment="single">NSPPVNSLTNEFFKEFSKLLKDTKNDSNVHGLIIETLLPNVFSAGLDLNYIRIPKSEPREEAEKRLKNYFLNFQDMLKELATYPNPTVALVRGSAPAGGTVIASLTDYKIGIENKRFTMGFSEVAVGLAPPNWINFLSQRHLGNKKKKIPSLPFISGLKNGHKYVALGTLTNDIHEAKSLGFLDEVCANNDLALESAIKQIEINLVPPTRSWKNTKLMQNQELVKMMNTEAVDFFWDSLGSFQFQESVKDIMEGLKSQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY44</accession>
    <name>A0AAD5XY44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anaphase-promoting complex subunit cdc27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CDC27</name>
        <name evidence="4" type="ORF">HK099_006622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the APC3/CDC27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000585">
        <property type="protein sequence ID" value="KAJ3214880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY44"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF13">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="430"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="464"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3214880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="631" mass="72691" checksum="0275E410D5417B6A" modified="2024-05-29" version="1">MILNTLIENSIDFYLTSNAVFLAEKLYYQCQNEESTYLLAKAYYHNFQFSSVYELLKQNLNHPPSMYLFSQSCIHLQKFSEGEAKLKNLLKIVDLNDPNTSFIYCTLGIILKKSFCFEESVKYFQDALLLNPFLWTAFENLCELGVNVNASEIFDQHSAQFFLNEMSNRLAFPNQSKIDDEKKSPLKNKNSKNYAAKFQFSQKNLKILPTALPSSTNLVNKVSAKRSALDSGLQDLHGNKGKKKILTRGTTHGNNDISQPSKMNLRSTSASANIKNNLTTAGKPSSLACAEIPNKEKKIALKNEENKIVRDETEEKYEVEVILDLLKTIGNGYYNLCQFNLEEALEYLQSLDLQQFNSSYVLGLIGKVKFEMGDYFEAENYFKKVRAVDLSNFKFMDLYSTVLWHQKKSVELSYLAHELIEFERLSPQSCYAYTLCGHEFHATEDYTKATNSYRQAIRIDPRHYNAWYGLGQVCLAQEKFDLSHYNFEKAISINPDPKIYFSLALVSHKAKKFEQALKYIDFSIKNNKEILSTFHFQKAKTLFEMERFQESLNELLKIKDMLQESNVYFLMGKIYKKLGKKKDSIISFTFAQDCLNTGSRMGTLIKDEIESLDYEGRAGNGESFRVLFDMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY66</accession>
    <name>A0AAD5XY66_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit beta</fullName>
            <ecNumber evidence="14">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ATP2_2</name>
        <name evidence="16" type="ORF">HK099_007954</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="14"/>
    <dbReference type="EMBL" id="JADGJW010000822">
        <property type="protein sequence ID" value="KAJ3211642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY66"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01133">
        <property type="entry name" value="F1-ATPase_beta_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000001">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.170:FF:000004">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000026">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039072">
        <property type="entry name" value="ATPase_subunit_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="169"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3211642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="498" mass="54026" checksum="452C10E15F07D3BC" modified="2024-05-29" version="1">MFLTRNILHKGLKAPFAVRFQSSNATPGSTGEVRSVIGAVVDVQFDAGKLPPILNALEVQKHDIRLVLEVSQHLGENTVRCIAMDGTEGLVRGQKVLDTGSPICVPVGPECLGRIINVIGEPVDERGPIKTKQVASIHADPPSFVDQSTVPELLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVLITELINNIAKGHGGYSVFCGVGERTREGNDLYHEMQHGGVINLKGESKAVLVYGQMNEPPGARARVALTGLTIAEYFRDKEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGGMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIAELGIYPAVDPLDSKSRILDPRIVGEEHYEIATNVQKILQNYKSLQDIIAILGMDELSEEDKLTVERARKIQKFMSQPFDTAFVFTGYEGRYVKLVDTIRSFKEILDGKHDDLPEAAFYMVGDVEEVRRKGEQIAKETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYA5</accession>
    <name>A0AAD5XYA5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="2">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_006922</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000063">
        <property type="protein sequence ID" value="KAJ3225381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYA5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:proton-translocating NAD(P)+ transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000002">
        <property type="entry name" value="NAD(P) transhydrogenase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160">
        <property type="entry name" value="NAD(P) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160:SF19">
        <property type="entry name" value="PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P) transhydrogenase alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="102"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="NADP transhydrogenase beta-like" evidence="13">
        <location>
            <begin position="221"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3225381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="674" mass="70461" checksum="80DBE8F37F2B2285" modified="2024-05-29" version="1">MSIGTHQHHFNIDLKDEVVRGSIILKQGELLWPPPKPVGPPAFAGMTAKPIEQKLSVDDSKKFKEISPFRQQLKEVMVATAAMTSLIALGKMTDAGFMLLSTIFALSSVIGYRIVWNIIPALHSPLMSVTNAISGLVAVGGMCLMGGGILPHTVPQFLAAISVLIANVNIFGGFIVTQRMLTMFRRPEDPPDYTYLFVIPAVVSAGGLIWAATSGVSGLVQAGYLASSLLCIASLGGLASQATAKTGSALGMVGVALGVVSTLQLSGFSPAVFSQFALITGIGAAIGTTFAKRITPTELPEMVALLHSFVGFAAVLTSAAAYIAHPAGTVLHLITSYFGVLIGGITASGSLVAFGKLKGLLTSKPLNLPMKNMLNLGMIAANTASLGLFLTSPSYAVGLTCVAINAAISFILGWHTTASIGGGDVPVVITVLNSYSGWALAAEGFMLQNELLTTVGALIGFSGVSTLAMNRSITNVLFGGYQTVTNSEVKKEFGSVTETNIDQLVMDILEAESVIITPGYGLAVAGAQYAIADLCKSLQKKGIKVQFGIHPVAGRMPGQLNVLLGEAGIPYDIVLEMEEINDSFPDTSLVIVIGANDTVNPAALEPNTPISGMPVLEVWKAEQVVVLKRGMASGYADVPNPLFYNPNTQMLFGDAKDTCDKLAKGVAESLNKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYM0</accession>
    <name>A0AAD5XYM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004329</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000030">
        <property type="protein sequence ID" value="KAJ3226719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYM0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="214"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="979"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="875"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1028"/>
            <end position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1055" mass="120828" checksum="46F6CE3B2C3A3FB9" modified="2024-05-29" version="1">MDADSGSQSRSNSLTVKPPHLDTSSSNLNLGNPAANFTKEFRGFFRLTACLDSGLTFLITIESNQSIEQLAKHIEAEHWFSYVVPRMSVDRQPEVKVKSRSNWSKSPLEVKSLYDKDRKSLDSTLIISKCFRNYDTVYVELEGKGLSAVPGSALTSYSYLAMQSTQNLDSESKKFKRKLINSFRFGDSSFANKSRKSFLIASSDMNISTTVDDRFNEILTNRLALMHFNEFCTDECTIHNLRFWIDVEIFKSCDASMRVLFANYIYLTYIDAGCKFQVRITPEVDQAIPWPILPSDDIESTIYNDAQREIYCEMRDQTFFKFEKSADFVKLQEKIIKDGNKYQNNKITKSFAHYFQPDIDKMQTTISTHNENEGPKMLNANDLSPEHRRQFKRQTRKLQNILGENFNEDMTNKLVFCHFVAEQLRQASEGKFEIDQSKIFNEMDDSSSGSDQDLDQSEVLKKKQFQKLFKLLGERIGSETEDEKKNEDAEPVGHNIDINFSPPLGVSLSSLNSALQDADDNDVDLLADPKRSLTHEEKKALQKRVNKLEKLFGGILPVKMLPSISLNKLADSEDHFSILNESDDDDIPSSPEEREMMRRKLDKLTNVLGERISPKTLEEEKEAVPLSPPQVQKALTQEEKRIYQKRINKLEKLLGHVPNSEDIISHRSTDILNKMGENYYSTEFLAENGDGKEKLSADNQHHDTDKMAKKKKLDKLSTKFGERITNNTLVTETALSPNTEIEMEKAPARPLTLEEKKALQKRGKKLEQMLGQSMPLENVQQHLVASSSEVLNVDDDTEEKSVDWTSDIEIDKESHKLKKKKLDKLANILGERITTDTLTTDQQKRIIKLAQFLAVALDSKLFKGEYLDENLHQDESDVTVEKKAAEKRLAELQKMLFILLKENLTDVALRESDDNEIVEIVTDLPERVLSKDEKKTYQKKSLKLEQMLGQSIPTNILVQTNTIQVPTLLTENISSRNSINDENKFEEETSDDELNQSMKEKKKKLDKIKNILGEQKITHNELSVEPQDPNNLLKSPQQSRIHRRLSGMMSPKFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYR7</accession>
    <name>A0AAD5XYR7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000038">
        <property type="protein sequence ID" value="KAJ3226345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYR7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070822">
        <property type="term" value="C:Sin3-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038919">
        <property type="entry name" value="STB2/STB2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011:SF2">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="PGBD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="547" mass="62465" checksum="4B4E89886580153E" modified="2024-05-29" version="1">MNLLFIDHSSDYCILVPEGDYQKHLDNLIVNINLKRLSCNEKGQINFKEPSESTKTKFLQNFGLRINSNSPGLKELISNFVEVLKINLQYFVKPEKYQSDLELDLNKLNLLDNETTSYLINFQKKFMQPEDEEDEIDEEGVSDEDQMVAPYVVKFLLNLVEIVKFKLEALGFSTLMACDSHHFRKAIKQFQRSNQLEITQHLNFETIEKLNEVFAKPPGQHVAATFNAVRNTFGDITGLPRKETKLNREDQLQQTLMEHDASYFIKNFLRDKETLLKKRSKRSSAGPRIAARKKSNDGTGQVSSDADDGAAARMMRGLKEGTSKTFGEFSKGVKDLVSIQNRDGNKTDIDSKNEIKNEFNNNIPTIQISAISPSAANTSLYSTQPFDSSSENLSEMTDSDSWEGDDEGNDNIGKLRKAEKADIVISSNEDLKSLTSTAPGEAEEKAEEDLKLSEDLKVMLVEINEKILKFQNDKVKPFIMEKKKNRKNFVEYKRNTNKELKTIKLKNVDNLKKLELLEKINIENFDLIEVLDDQSFKSNYQMTVLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZJ2</accession>
    <name>A0AAD5XZJ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_002870</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZJ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057246">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00132">
        <property type="entry name" value="CARBOXYPEPT_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M14" evidence="11">
        <location>
            <begin position="115"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3228365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="409" mass="45611" checksum="11B3B77731F94879" modified="2024-05-29" version="1">MMLLSLTLFAVAAALPATTKQKGQVLKCFVETEEQANTYAKLEVDTWTHHVSVGKNLQVLVKNEQEKSAVEKIFGTCSVEIPDVSSYIEETRDWMNLDDSASSRVVADDTEFFKAYQKYEAIISKLQSWASSNPELVTYSVIGKSVEGRDIPVLKMTNSNVSDSSKKAIFFNAGIHAREWLAYSTNLYLISKLLSESGTNPTVQSWLKTTQNPDGYSWTYNPGGYRFWRKNRRVNRDGSIGVDLNRNFDEHWGQFGTSSSPSSDVYHGTSPFSEPETRSVSDFILSIPNKIAGIDIHTMDQSILRSWGWTKTNSKNENILKKLGDGMAAEIKNNSGFVYRSEKSASLLASGCEDDWMTAKALINGWTLELRGPSFNVPPSNIVPAGEEIFAAITYFINFNLNNVIPPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZV4</accession>
    <name>A0AAD5XZV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000373">
        <property type="protein sequence ID" value="KAJ3218578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZV4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019141">
        <property type="entry name" value="DUF2045"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21477:SF13">
        <property type="entry name" value="KIAA0930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21477">
        <property type="entry name" value="ZGC:172139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09741">
        <property type="entry name" value="DUF2045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="217" mass="24493" checksum="C6C3CACC643153B5" modified="2024-05-29" version="1">MEVYYTINDYESKDLHLKIKEQQYLCVELSIVYPIAYIENAKNLDIEGLLNSIDLKKDSLPFPVPEGYKKIIFFQGAVPFSSLIEIYQQKVITSNTGIQNKLKQSWGKLNQTSNSSTSGDKLNERVEYIMMRGPHGKGQCQVAIKEVENSANGGASLRNKNSSSWLKGFSTNIINSTSLLFDNNETKSLSLTVDELMCSMTYVNIPWQSIISDLLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZW0</accession>
    <name>A0AAD5XZW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000022</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZW0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3228467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="221" mass="25582" checksum="8A5737792189FD5A" modified="2024-05-29" version="1">MPENLKLKPRISVIYPELVDEIQRKERKKRFLVYVVIVLFVLQLIVRIMFPAASFFAAPHAPPAPQDPPEDIKNADYNNLPQNNGANNIPAKNIIKAEEVKPDIRTIINAETATTATPDNKESLKKTAENKNKKAKQADKILEYYNKLNKMEKLKLELKKHIEKEEGSDSEEDEEEIYELLEKIGKHLKKNLLKTAKGATEVYKKVKENTFTWRREKFGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y018</accession>
    <name>A0AAD5Y018_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000346">
        <property type="protein sequence ID" value="KAJ3219239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y018"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF82">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="356" mass="42231" checksum="40ECBDF6F330D940" modified="2024-05-29" version="1">MLKSKNAKKILQSQNKPNLDYLCPTRLQTRVNCLPYEKPAYNNTTFNEAVKALQSFTKVNNITDQVYLDFANFEEHYKFHAGKVENGSNETFKKMEELRWKNIIAPKILKFSKEYKIFEHIFPKKFKTKVQLTCNWQYTKWLGMYGHDVPPNWCLYSPTVNIVTNSPKEKLYTLMMTDLDRPYPKDGILEEWCHWKIVNIPVKERLEIRGGESVFLKSNPDNVNCFNLQTRFPFRPNQEKRKQVGDTIFPYIPPHPAHSNPRLTRRYLFTLIEQKELIDVEKYKNDLKLQSVKEYKKKNTVEELKEMEYVERGLFLPTWKYVTETKSKVVSNFFICFYNFSIRLPVMGLLDQAGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y040</accession>
    <name>A0AAD5Y040_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Guanylate kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_000221</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000104">
        <property type="protein sequence ID" value="KAJ3224110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y040"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:GMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.10:FF:000002">
        <property type="entry name" value="Guanylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117:SF13">
        <property type="entry name" value="GUANYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117">
        <property type="entry name" value="GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="7">
        <location>
            <begin position="461"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3224110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="672" mass="77118" checksum="1BE34AB344C6ED76" modified="2024-05-29" version="1">MEVKKLSQQQQQKLSQRSLQNLKKSQQNLNKSLQNSREQSKSNSIANLLKQVADTTDSEFEGKPTEDLLLNKTAINESNTEELIKKKEDVKIEDSEEVDFNNRLKNLPLSFELLKNGLSCLGLCPNGLRNVYLRLSLPGANLTNINFLKNFVFLQNLDLSGNNIEDVSVLEFNKFLVQIDLSDNKLASILNLENGQPPYNLQELDLSRNYISDICSLEKLRFLKRLCLDYNDISKLDGFSSCKFLSHLSISHNKIGKIEGLNGLPLRYIDFRHNQISSLSGLSTLIKLEQLFLGNNNITSLQYDRLKNNFQPENHPYLRQLHLENNYLTESEELSVLTVLTYLRDVKLEGNPFTFEGTDYGEYGTTRRISVNTISDLETQNSVCQTFDAKPEERYKLHLFFLIPNLKILDGFEITAEEKVAALNRYNPPVEVIGSIRHACLMQREVKYLAKIKEKDIKSHKKPIIICGPNGVGKRTLRNKLMAEFPQVYGNAISHTTRKPRHGETNSIDYYFIQRHDFKKMNSENKFVEVVEMFGNMYGITYDSIKKVQEDGKICLIDLELEGVMNLKKSSLAPLCVYVTAPSMDILATRLQSKFSRGTVSSQNQLVHSNSNTDSEYIQQWLCQAKINQLDVNSEINSMFDLKLVNDDLSVCYNELKKQLVKWYWESYGKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y068</accession>
    <name>A0AAD5Y068_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003582</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000236">
        <property type="protein sequence ID" value="KAJ3221322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y068"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="273" mass="30862" checksum="B560AFE9F92E031B" modified="2024-05-29" version="1">MKRSGKSSLKDVHLDCLLKWLKEKQAGLLNNNYCPACKFQYKIKLQFDPIRFVVKGVNRLIDFVVPFYTVGVCCVGVYIMSFSYGGTNYYTTNFLKSIVYAVLQTCSEELSSSILNFQQPNFKQFIGLPMIPLVTLALIFNRTNYGDTILPCMSFLIFGNQTLSLTQNSGIISMNALTLTPQLMVCFFPWVRIIYQRCLKRLKKLILGVDIGVDEYGVENVDNIVEIGDSNGRRKGERLVIGSLLFPGVSSIAGSILSQFSVFRNYLPEVFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0G9</accession>
    <name>A0AAD5Y0G9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000280">
        <property type="protein sequence ID" value="KAJ3220689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0G9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041990698" evidence="3">
        <location>
            <begin position="22"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="480" mass="53554" checksum="F0506851B24DCC8A" modified="2024-05-29" version="1">MKLLNFFQLCFLFGVLSLALSELSPNLIINGDAEAGVANWKWNSSSENFLSSTSYTGINITRGIILNDKNRLHLGQGCFQAKYGKIDSFVSKIFSATQTLAIPENLKRSTATGQSTFKFSSSFIRFFFTNDYVKVSLSFTDANNQKIKFQYQNALTLQYENGIVDTIGGNIKPFPGNSTSQAYFFSEISNGTVPSNAVNIVIEMEFSFLDAEKSLVSKAFVDNIALVFYFNKDTAKVGFLQRADISITGWIGIGVGSLGLFLLFVMVPIFTCFKKKSSPMLKKFTLKRRNSRDTQKRPPNPQISHHNLVQKSKNRLSNFMSTRHPQSFPYPAHSNPSNNSATSVNSSKVLLSHSPQQNQFTQFLQNVQPSPHIHSQHPYAPVSAPMYSQNLVHQQHTVQGQQNTNPINKQQPPINLTQLSQQQRYPLSHVRPSSIQHQRGVIGSKSLFNQSNNSSIPGMSSSGSLSNSSHLSNDHRVYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y152</accession>
    <name>A0AAD5Y152_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">U3 small nucleolar RNA-associated protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HEATR1</name>
        <name evidence="12" type="ORF">HK099_005264</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the HEATR1/UTP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000040">
        <property type="protein sequence ID" value="KAJ3226267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012954">
        <property type="entry name" value="BP28_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056473">
        <property type="entry name" value="HEAT_Utp10/HEAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022125">
        <property type="entry name" value="U3snoRNP10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040191">
        <property type="entry name" value="UTP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457">
        <property type="entry name" value="BAP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08146">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23243">
        <property type="entry name" value="HEAT_HEATR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12397">
        <property type="entry name" value="U3snoRNP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 10 N-terminal" evidence="10">
        <location>
            <begin position="225"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Utp10/HEAT1 HEAT-repeats" evidence="11">
        <location>
            <begin position="1301"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="domain" description="BP28 C-terminal" evidence="9">
        <location>
            <begin position="1777"/>
            <end position="1843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3226267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1980" mass="224234" checksum="4DA46CF302566F95" modified="2024-05-29" version="1">MPSLKDQLKGIQKLSQSAKNQPSLLFSKSGDIDSDAVLDLAKNGLAELVTKDKRFLAFEDSIFSDFYKNSNIELQSPEILENLKKSIANFLILLSPYFLLKPSLKVLEWLIRRFKIHKYSIEQVMLCILPYHESLQFVNLVSLFQFHDTSSKWSWLKIVQQTRVPLDRNNLVQRCYTDSSILNSIFEMVRLNLEVQVVNKPLWSFFATTVVHYIAAAKKVNEKLVRTLLPISFEIMKFKSDTDLQSTALMIFAQICHRSQLSNEVLKEIFDSIAIYVVPQLEYLSLLTIITICQTQSNENVKFGSQIVKRLSEFSDLVGNLTKVSISYQVDSFLIPFLKALEGASESNNCYYILLLRLIKYQGMDAGVRKSVISPLCDELLKRFLILNKNDERASSEMIQLLQGIQLHYSEDLSLSVDQQLTVLKNGKTDVESTKALYSFISSTFQNTLFQPDYENNTVLYLSLYHLEESVRIVAYKRLSDLLQQGDQILDKEFLDSVILDGFESQSNSISETLLEMPLQKLIDHDKLVKALITVVEKSGKQWLPNRIRALDMMIQVVIAGKVRQDIIVEVEESFQLASCALELVAQPDFPFKMLAMNRFTFTAALHKLSDSINPVVTEKLCKILIKVANAIAGINGIETKLFEMAKSSRKNVRYLSTVALFCLLQNSKISKKVFLANTFIEHIREFFKTLNIRKLKKLEITKEGRIPKNLLQAMVLYNDSIPVDEYLIFSTLNLIIRQIAKPKNLPNDLNIWSEVTKNKAEFCEEYQLLMKKVYVFVLVGSKFDVSWSQLLEVFFSYHSKEDCLQFLTSFLIDKNSSTNVLVSSLNICSGFILSSVDANNAIDYQLFIPVILISLLNIDNGVRQEAVKCLEAIDRSYQLKSKNFSIYAYDQFFGGDCSKVQYLTTNIASKFVSCLISQKESLLTTEIYLPNVMESVLGATEAESIEWEASVLLFLNTCVLACSTSFGKVQILNSMKLIKSAIKIKTLYPLIEDCCSASYPVDERVLLLPQLVKCFDVPISNRLFDGKQRKFFKLFLKLLSDFNLTENFSTQVSMLTFITEDWFSSVSLKNQAEIFSIIVLLSVSDSTVAGLAKRVLSAITLDASILTSQFTHYITLIQDNHSQQIKRLKADSKEEVPLFSLITLLELFSSLNIINKRTLVRNLFEFLGVAVSTQNVSIFVSLEYIKQLILAALLDVIAEVKDTSDENELRVDYVVQCIRTTDNPQTHNASLILMAAIAKVNPDPVLINIMPVFTFMGANVLRQDDNYSFYVIRQTLETILPALLSKHNNVSSPHMQMILSVKPVLKVFVDALFHIPKHRRLTLFSILVSVLGPNDFLQPIISLLVSKAVGMGQIRSSTASVNNAVLEFAASVSCHFDISSQLKMILESLDLVKGILNTEDDTATVSFFDSNDFNEAQLYNLQVAHIECISIILGNPQFLEKLKLVTDVQKLEDYHVKLVGTLFSIMSSGRILQKKCETEDNKLGVSFSNNLVSSGYSCLNEVHELLTIKTFIKTIAKLLVSEDTTIVCKSLTLLNEKTTALKSTAIDVEVGKLYSSLVPVVLQVIEGKKSSHECKQNGLLCLTTMIQLMSKKDVEVYIRVLPLVCEEINSSVQNVAISALTCLTCLCNTLGTRTITHLPTFMPSILNILSDAIKKKDLSTSLKGSQLFIYTSITALTMIVKALPKFISPYIPKILDCCLSPLYLNKVEHNKAHQKISEKNLELCFILTERVPCRILLPAMFNHLKASFKNGVQSLMMLFRMTSKILNLMNSSELNDQYLGVFRFFIFGFDYRESIIDVENYLAESCDEELISSFLTFVGKLNDAMFRSLFLNMVEWAFAEEGLMNAEKFHKIYPTVIKQITKKELHSLNYLENMNKYLIPCIGQLAVNVNADDLWKPLIQSILMTSREEDAEIKITTLKSLEELYRLLGEDLLVFLPETIPFLAELNEDDDPKVEKASLKLCSVVEGYLGESLEQYFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1G5</accession>
    <name>A0AAD5Y1G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein kinase, membrane associated tyrosine threonine 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PKMYT1</name>
        <name evidence="8" type="ORF">HK099_000881</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000122">
        <property type="protein sequence ID" value="KAJ3223643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1G5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110031">
        <property type="term" value="P:negative regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF190">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE MIK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="67"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="38263" checksum="E4B6FB4403BA4FD9" modified="2024-05-29" version="1">MNDGFKIPLTPFSGPTPKLNNSNQIFSTPNSAPQPSKFKPLPQAFHSTGFLKKSKKNESRNLVMPDTPLKRKYQDQTCLILLETNNKKKGLSINQKQLHQLQLDEKKFNLMSSELRILNKDYFKNASVNSNGYHQNSNSQVDLNFNNPNNFYVNSVDLFDEKFILLEKLGSGSFAEVFKVVEKGTNVEYAIKKTKKVYQAHRDRMLKLEEVELMWEDFGMASRIPVPRGIEHEGDRTYMAPEILENTYTKKADVFSLGLIIFEIALQIVLPENGQNWHILREGKFDEFDFGNLSLELVQLIKLMLEPNYEKRCCIDEVLTMAKRRASFYGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1P2</accession>
    <name>A0AAD5Y1P2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytosolic Fe-S cluster assembly factor nbp35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">NBP35</name>
        <name evidence="11" type="ORF">HK099_001680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1P2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904564">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly scaffold complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000427">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03038">
        <property type="entry name" value="NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028601">
        <property type="entry name" value="NUBP1/Nbp35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF35">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>ligand shared with heterodimeric partner</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="311" mass="33631" checksum="12780D7B471D25E1" modified="2024-05-29" version="1">MSTRPENANESCVGPNSTEAGNATSCEGCPNQQICKTAPKGPDPAIPIITQRLSTIKKKILILSGKGGVGKSTFTTNLSFALSLDEKVNVGLMDVDICGPSLPRMTGLDGEQIHSSNSGWSPVYVTDNLSVMSIGFMLQNPDEAIIWRGPKKNGLIKQFLKDVDWGELDFLIVDTPPGTSDEHLSVVQYLKESGIDGAVVITTPQEVSLQDVRKEINFCKKVGVPILGVVENMSGFVCPKCNKETLIFFPDSGGAEKMAKEMEVPFLGSIPIDRRIATSSDLGESFLDQYPNSIAYNSYMHVIAEIKKNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1S6</accession>
    <name>A0AAD5Y1S6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000101">
        <property type="protein sequence ID" value="KAJ3224196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1S6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="229" mass="26554" checksum="159ED528AE96859E" modified="2024-05-29" version="1">MSLNVFKQSFFLNTKNLSKVPFCQLARVRKMTSYEKASEDVRVSLMLYLFTLFKVIFTVAALGDHEAQKERLVREIMAVDKVERIHAKTRFEEIKNENRKGLFSAMLPYRIGILLSSGSALLSIPLIFHEETVMYFNHHFVTADIPEPKDLETCLEVGSFSWNWMEPVLGTVSFALLCLQFARNQIRNIGAKPFTSWFKHRRSKKLISQFPQYDKFILRSFSEGDPLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2R2</accession>
    <name>A0AAD5Y2R2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal RNA small subunit methyltransferase H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007427</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000072">
        <property type="protein sequence ID" value="KAJ3225052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2R2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00006">
        <property type="entry name" value="16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265:SF0">
        <property type="entry name" value="12S RRNA N4-METHYLCYTIDINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="S-ADENOSYL-METHYLTRANSFERASE MRAW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="Putative methyltransferase TM0872, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="36791" checksum="BC8181D73537192A" modified="2024-05-29" version="1">MAFSHKPVLLHDIINNLKTLQLTKPIVNILDATFGEGTSQNQLEDKNRGFGFNVDGNLDMRMSGDVNQFLKIFQQYNREFLKADFEEKSSVIDNNLTAESILNTFSENDIADILYLYGEEKNSRVIAREIYRARKENPLTTTYQLKNVVEKAIGWRRKGVHPATKTFQALRIYINKELQEIQAGINFSLQNLTANGYLFMVSFHSLEDRIIKKNFKCYEKLEYVLILIEFEGDLIVRGEPLLKILTKKPITPSLAELELNPRSRSAKLRIAQKNGEMHIEEHLLFDKKLSEEADVGFDLFKKDSVLKKKIRELRKGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2V1</accession>
    <name>A0AAD5Y2V1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ (Hsp40), sub C, member 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DNAJC17</name>
        <name evidence="8" type="ORF">HK099_005147</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2V1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052094">
        <property type="entry name" value="Pre-mRNA-splicing_ERAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="8"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3226316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="282" mass="33330" checksum="4391D41F2655E8D9" modified="2024-05-29" version="1">MTEEGFVDFYSLLSIDIDTATKKIIQKAYREKSRTAHPDKGGDNETFHKLTIAYETLLDESKKKDYDQTFKAKKQRELKLQQMDKKKRRDRENLEERERLVKKNKIGGEDYNENLKNKLEENRLRTENYKELRNFQNKMENFALRNDKLSLDTPKNLDATLILKWKKKKFNFTKEDLMNIFKKNFNNYENLIFNDTDKEKKKMTAIISFSSILSANSVMNSKIEELQAFEIKWANGFPPAALATLLKENVQNQEEIMVDTNVPEGMSFEDYEELILMQTLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y419</accession>
    <name>A0AAD5Y419_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y419"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="114" mass="13378" checksum="0A276BB42D5FCD2C" modified="2024-05-29" version="1">MSKDDILEWFQRKLNRQPEAYDVYLVGKEFYQLGSYSRAMACLQYHVSMPGASIPGRHLLGYCYLNLHDNERALREFKKCVKDGFQDDWQLIVELIYEIDEKINASANDNYDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TST1</accession>
    <name>A0AAD5TST1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002783</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001953">
        <property type="protein sequence ID" value="KAJ3200192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TST1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3200192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="349" mass="40036" checksum="8B0BF05284C9F9ED" modified="2024-05-29" version="1" fragment="single">MDLFEAITKQNGFPLNVVKEIFLQLLNALIYSHEMGIYHRDIKPENVMISKDFKVKLCDFGLATTDKFSTEFGCGSIRYMAPECMNSSKLRKCYSTAANDVWSMGILLINLLFGKNPWHEASEKDPIYSSYIGHNPQVLKKQFNLSNEGESLFNKIFELDVNKRISLQQLKSLIINIPSFTQQKEETVVIKTPELLPRKQIFLETDQSSTNSTTCSETPFEILYLPSPAESFNTLTNFNNCTVLDDEIRSSSNLNPKSPKREQKKKYQAKQNLKIETNFLQKKNIKIEEEKVTDSGFCTSPFSPTFDERVKKFTSKNNNNNISSPQQQQPLSAKILKKFFNWIGANEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT30</accession>
    <name>A0AAD5TT30_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001935">
        <property type="protein sequence ID" value="KAJ3200281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT30"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="96" mass="10932" checksum="9E32B237456F75EB" modified="2024-05-29" version="1" fragment="single">MDESFRLRGQVRALRLKLLIKAENEKVNLPTNATKIPENAQKIPTNAMKMLPKFLPKLRLYKKQSFSEFNTMKLNKEQSTFRPCGVCGTSLVAGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT44</accession>
    <name>A0AAD5TT44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002739</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001932">
        <property type="protein sequence ID" value="KAJ3200298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT44"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="169" mass="20262" checksum="78F6D9E412083457" modified="2024-05-29" version="1" fragment="single">MSFKVKKNASFEKLGFWFWLQEGTLFSAEIKEQKNLDLGEEKFNLIRKIPLIENQLNFKKEILLLGNQGEFKIYEEKYKNLKKKKNVYPGFNNKKLKRMSFLRFKSTNFEFLLKSEKNYLEFISLYKIFDENKYDFNLMFPSMPEFSGDCLSLPFVCLGSIEVKHRIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTW9</accession>
    <name>A0AAD5TTW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NadR/Ttd14 AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001567">
        <property type="protein sequence ID" value="KAJ3202473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTW9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070300">
        <property type="term" value="F:phosphatidic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053227">
        <property type="entry name" value="TRPL-trafficking_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34932">
        <property type="entry name" value="TRPL TRANSLOCATION DEFECT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34932:SF1">
        <property type="entry name" value="TRPL TRANSLOCATION DEFECT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NadR/Ttd14 AAA" evidence="1">
        <location>
            <begin position="14"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="317" mass="37159" checksum="387DA67D9DB8D1DF" modified="2024-05-29" version="1">MAYSFQKDLLTVMLSMENTYMNLAKLSAESGKKAVVICDRGVMDPSAYIPRDEWLQSLTELNLNETDLRDNRYDVVVHLVTAAKGASQFYSLENNDTRTEGLELAIELDEKVMNAWNGHATLTVIDNESVENFHQKCDKVVQAVMNRLGIVSEETKKTVVKRKFLVKNFNWDAEFKVPSRDFHVEHVYLSKLSHDGIQVRIRKRQEFHTKGSYSNLTMRHRTIDGQRVETRRNLQPREFELLKINMDQTRVPILKKRRCFLYNEKYYQLDYFMRPKDGLVLLEAYLDFQGMKGLPDWLELTEVTDDKSYSMFELSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU17</accession>
    <name>A0AAD5TU17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001542">
        <property type="protein sequence ID" value="KAJ3202631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU17"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="128"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="392"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="51421" checksum="E6C33B09FE2DEB09" modified="2024-05-29" version="1">MSSSTYSNIIADTLEMTGLITYKELSRIANCSVNDSKLALKLYSQNNKKIKTTYFKKLENKLIISSIPGDHIYSLHLKNPDSDLIFQRDLLISTEDIDPSNFRVIKSTVSLRNSKVLPVEQPSLLNNLKKNLNPINSSSNSTTTKDEKSLHQNKKPLERPSTTKISNTKSKNESSSKSLKQQQQSMSSFFTDFQNKKKEIKPYVVKEESEQEEEEEEEKTEKIEIEKKKEKIEIEKKNFNNDIEKINIDVSKNKKIIQTVNIAKKKLSNEQKLEELEGKKELENLFSSDNEKNDKMECENVMDVKNTETNTEITLPAASKRVKRKRKVKTKEHFMDGKYMKKRIVETWESFSESENEVETIKKVIKKNDENLFINNNITTINNTSNKKQIETTKKKDTSITTTKSNTINSLSTTTLKTNSDTDFDDDNKISEKKKTTPLLSKKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU29</accession>
    <name>A0AAD5TU29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-dependent DNA helicase sgs1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SGS1_1</name>
        <name evidence="6" type="ORF">HK099_001112</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001297">
        <property type="protein sequence ID" value="KAJ3204468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU29"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF153">
        <property type="entry name" value="RECQ-LIKE DNA HELICASE BLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="438"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3204468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="517" mass="59588" checksum="4E1C8E16E802DF40" modified="2024-05-29" version="1" fragment="single">MSKAPFDNFAEQLQQFKLKNSLKLENNNRQSKLNNYYIADQNKENIKTDHQINLTKRNSGLFKHETPASKRLKVLDANTSYNSNKIYSTKKSEVNVQPNHNVKVEQNVFTPNRLSNSLMKNASSNLNCKIQNILKPDYLPGEGLMNNKERKWKEFLAKNITEKHIFIIIESLQNQLKENFNLFSDMNGGMSSDLMEDIKRSQDSLKSEINLFKEAQLDYFGKNERTSNVFEKDEETNLNFNERKDKKNFFLEKESHLSQTPPQKLENLQNDDYLENDETMINDQLGHYNDFDADMMGIENADDIVAVDSDPMYDDFDNLNQDMLHNFNDVEKVDISPIQQNSTIDYNIQLDNNFPGDERYFENDWKDFNDGFEEEALDNLFQNDFSFTQSSVKCLPKTDFNSEKNKAAVTYKWTSEVFSLLANPFNLKEFRQNQLEAINGTLNGKDCFVLMPTGGGKSLCFQLPALCQNGVTKGLTVVISPLLSLMQDQSRKLVEMGVPVVVLNGTLDQKGKDFVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU84</accession>
    <name>A0AAD5TU84_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001245">
        <property type="protein sequence ID" value="KAJ3204981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU84"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051481">
        <property type="entry name" value="BTB-POZ/Galectin-3-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410:SF23">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410">
        <property type="entry name" value="HL07962P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="420" mass="48042" checksum="48525463EC22F5E5" modified="2024-05-29" version="1">MTTLINNLDNLYSSNNFNDVTFIVGPEKIKVEAIKLLISINSPVIEKLLFNNMIETKQNVIELPNCFPEAFKILIRFMTSCLVDQTLFCNNQKLVLQVAETARYFDVPLLFEFSLKSFADNLNLKNLFECIELSKEFVFKKVENYLSFFIEKNALAILSLEETKNFKFEQLHYILKNLKNIPHQYEIVMCLIFWYKETQPSNENLKSLLDLVDFTIFNGKQLLALASLGEVGASMLVAILLDRAESDLVSPEKKFTTPLQFERLNEYTATNEYTSFSQETETVLANKHCVPGTITTWDIEVIDVGGAFWVGICTDQVDRKKFGGRQPFGWLYSANDRRVHNNKEEPKLGLGETGKINGGILRLSLDLQNENRKLLISKKLNNSEKFSPSLPAFQNLPDYLYFFPAISVRIGSVARISQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU93</accession>
    <name>A0AAD5TU93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001405">
        <property type="protein sequence ID" value="KAJ3203604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU93"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="175" mass="19197" checksum="6D3197F15AACFEEB" modified="2024-05-29" version="1" fragment="single">QQTLFTPFNNSPINSISSATINYIPDASVHNKYQSYNSTLDSSISIPAINQVDSVFSTNDQVNSESVFSTNDQVNSESVFSTINKDSIFSSNNQAFEIYSPPSDSGFYINSLDSSYAQINQNIIGPSLLKSPSVKSLELEPPMKQPLKKKPKRKPRPKGSQSSVGKEKTVCTFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU99</accession>
    <name>A0AAD5TU99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CYC3</name>
        <name evidence="13" type="ORF">HK099_000902</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010001229">
        <property type="protein sequence ID" value="KAJ3205145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU99"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF3">
        <property type="entry name" value="HOLOCYTOCHROME-C SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00821">
        <property type="entry name" value="CYTO_HEME_LYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="247"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="31"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3205145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="352" mass="40478" checksum="7F879BDD92873584" modified="2024-05-29" version="1" fragment="single">MGWFWGSQNDVKPVATSNSGCPVDHTKINKSDSSCPVNHTQMSKNADSGCPVDHSSKNSKNENINPLNQMPNLKNEMIEGQIEPLSTKKTLSSIKNKVDDKDSVWEYPSPQQFYNALVRKGWETQESDIDTMVSIHNFLNEECWKEVLNWENKYHCDCTEDRSLIRFKGRPQEPTPKALILTKLGLVERPFDRHDWTINRCGKEVRYCIDYYGGDDVKQADGSNSGEDLPVFHCDKSVYLKFTARHTDTVKKDLDDIVKKYEPKDVRLVKKDENLSVKKFRKSLAYADFETKEAALKCATELNGIKRNGFEVKAFVSKLSNTDNQIYLVRNLPRNLEFGKFKKLLTDFTAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUC7</accession>
    <name>A0AAD5TUC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002219">
        <property type="protein sequence ID" value="KAJ3198969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUC7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="186"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3198969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="273" mass="31289" checksum="DD03C1BB68B45AC6" modified="2024-05-29" version="1" fragment="single">MDAFIVESEKRDDGYKELEKTTPRQKPSTPSFDNNSTNTYLINSNSTPNFRETEKFSLKFITNAGYGTVEENEETNSVEDTSSLIMKIKTQNGVISEISKRLQQTQKLLKGTQDYLQTREQTIKNMEEQKLIAELVNAQVESNFQQANSRSRSARTASAKVDETTSLIPHEESIQELVQDEQDFKMETYEEQITKLIKSLKEENNEVETTKKSHSGKSVSIVENPVILNPQQPDEETKRKSLYEKKLEEAENKNYNAVTDEKISKEMILEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUL1</accession>
    <name>A0AAD5TUL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nitronate monooxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000568</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nitronate monooxygenase family. NMO class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001130">
        <property type="protein sequence ID" value="KAJ3206362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUL1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42747">
        <property type="entry name" value="NITRONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42747:SF3">
        <property type="entry name" value="NITRONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3206362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="47657" checksum="E61A14B492B7BEE4" modified="2024-05-29" version="1">MSTNLQKLLNLKLPIIQAPMANVSNPKFTSMASNFGILGSHGCGLLQPEQLEKDIMELKSLTSKPFNINLQLPRPNLQAEKVKRLSEVEVTELLTEIRKELKLTAPKEIRAKPNFFEQLKMIEKNPPKVFSYCFGRIEKDAVKRLKDKGILVVGTATNLQEALDLEEDGVDAIVLQGSEAGGHRSTYISDYKSGLIGISTLVPLVYSRIKSIPLIAAGGITNGNQVRALLSLGAQLCQIGTLFIPTLESSISLTWKENVLRKSPDGNKNTVITSTLTGAPCRVLENKLVRFLATWEERGVPRNMAALISDVLRNGGHEFGISMMGQGSENDAAKAVLRTSALQLLDAGAVVRRLSSYGNEEQLPYRMKRHQTVHSTGRYVSILFDSSPKVMKELHKTLGFDERVIRRSVVNVADTLKKSSELHVTRYNLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUX3</accession>
    <name>A0AAD5TUX3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_000835</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001209">
        <property type="protein sequence ID" value="KAJ3205377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUX3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001473">
        <property type="entry name" value="ATP-binding cassette transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041936861" description="ABC transporter domain-containing protein" evidence="10">
        <location>
            <begin position="16"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="692"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="781"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="805"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="11">
        <location>
            <begin position="39"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="338"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3205377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="866" mass="94253" checksum="A9CE0BED94B939EF" modified="2024-05-29" version="1">MNLAIILGLLNLVFSQIQTNQTINPTNLNQTIQCPICESTFNCLTNKNSCNEFASCSTNGQCICPDGWTGVDCSKPACNSTNFEPQFRTPRSGNQCQCDNGFIGQNCNVCTQDSVCKGRSNAPVGSTYVCNKLNTVWQNSNMYCDVSVAELAFLFPNKVTATVNRNITGGTTLANLWYEDIEQFYCKAEQCSQKIVDLEYIWSCQQVKCRCIPGTKFCGNGGTIDLTRIIETEVSGSFSVNFPSETADMGTLFFDSLKAVFKKGLPLGPCRVGECVDPGYKINLLPVVTPPLSPAAIAGIAVGSGFLGLILFSLIIAKIYQLRLRKIPLPAPRTGAQLRFRDISYEVNNKSILKNVSGCANSGRLMAILGPSGAGKSTFLDILAGKKKSGKVFGDILINGKTMSSKKFRAISGYVDQEDLLIPNLTVKETLLFSANLRLPEGVTKLQKEKIVQETLDTLGLSHIENSKIGGNGVRGISGGEKRRVSIGVELVTSPSILFLDEPTSGLDSYNAMMVVKTLHTLANKGGKTLIFTIHQPRSDVYKLFDDVLLLAKGSVMYMGDAKEAETVFANQGSPCPSGYNIADHLLDIATLEALNEKPEAGVGIAVDAFIISDQTNETLRLRKSNKMEKSDFSDPYSIIDSNSSYSNSGSDPNSTTYLTSTENTETFSVSFLTQLNQLMGRSSKILFRESGLLLAHVLISIILGAFVGALYWRADSSLGGFQNHLGSNFFCLSLIGFSSLSAIGTFTTERLIFLRERSNGFYGPFPFFLSKILFDILPLRLIPGILMGTITFFMIGYGGSFLKYIVVVLLFSSQCGMFCLAIACAITDFGTATLVAAISMLFQMLMAGFLINAGRKKKKFLIFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV15</accession>
    <name>A0AAD5TV15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GDP-mannose 4,6 dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GDP-D-mannose dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_002336</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:23821"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010001769">
        <property type="protein sequence ID" value="KAJ3201185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV15"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05260">
        <property type="entry name" value="GDP_MD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:001053">
        <property type="entry name" value="GDP-mannose 4,6 dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715:SF1">
        <property type="entry name" value="GDP-MANNOSE 4,6 DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="GDP-MANNOSE 4,6-DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="10">
        <location>
            <begin position="28"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00050823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00071431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3201185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="373" mass="42437" checksum="218C706CD5CC3639" modified="2024-05-29" version="1">MSETQELEIGSEVSNNSIGDNNQRKVALITGITGQDGSYLTELLLEKGYTVHGIIRRSSSFNTGRIEHLYKDPHQKTRLLLHYGDLTDSTCLVHIISQVQPTEIYNLGAQSHVKVSFDMAEYTADVDGLGTLRLLDAIRTCGMTKRIKFYQASTSELYGLVREIPQSETTPFYPRSPYGVAKQYAYWIVVNYREAYDMFCCNGILFNHESPRRGQTFVTRKVTRAVANISLGLQDCLFLGNIDAKRDWGHARDYVEGMWRMLQQEKCDDYVLATGETHTVREFVEKAFKVVNVDIVWEGEKENEVGLNKETGKVIVKIDPKYYRPTEVEILLGDATKAKKNLGWERSCGFDQLVEEMVKADCEAVKKNPNDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV96</accession>
    <name>A0AAD5TV96_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008610</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000967">
        <property type="protein sequence ID" value="KAJ3208959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV96"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF16">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="6">
        <location>
            <begin position="51"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="5">
        <location>
            <begin position="135"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3208959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="443" mass="51368" checksum="042AD9004764803A" modified="2024-05-29" version="1">METNLKRDISSTELETDNNSKKLATIDDFDDEYFQLQENKRTKRNQKNTVHSEIYLDTINRNLLDFDFEKVCSVNLQTQNIYSCLVCGKYFQGRGPKSHAYYHSLHQDHHVFINLTDLHVYVLPDDYLVEEKSLNDIKNVLNPTFTEEDIKNIEESYKNVKNFSQISFSYDLTKKSYIPGYIGLNNVKANDYINEISSASKKKFIMLKQNDPIEFLSWFLNSLHTSLVQGPKKGKTSIIHDLFRGELKIESQHIVDSTSNSAPQTTDNENTENKKLFDLTKEVQVKVSPFMFLTLDLPPPPLFLDDLDKNMIPQVDLTTLLKKYNGETEQEVEGVIKRYKITKLPKYLILNVKRFIKAFKLPVTKNPTIVNFDLTLDMSEYGGGIYDLVANASHEGKSEGNYKVQLKLGLIWIQIQDLIVEEILKEMICLTETYIQVWQLREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVG6</accession>
    <name>A0AAD5TVG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitotic spindle-associated MMXD complex subunit MIP18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FAM96B</name>
        <name evidence="5" type="ORF">HK099_000101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001005">
        <property type="protein sequence ID" value="KAJ3208241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVG6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140535">
        <property type="term" value="C:intracellular protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990229">
        <property type="term" value="C:iron-sulfur cluster assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000005">
        <property type="entry name" value="Mitotic spindle-associated mmxd complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028009">
        <property type="entry name" value="ESCO_Acetyltransf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039796">
        <property type="entry name" value="MIP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13880">
        <property type="entry name" value="Acetyltransf_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIP18 family-like" evidence="3">
        <location>
            <begin position="36"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase ESCO acetyl-transferase" evidence="4">
        <location>
            <begin position="241"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3208241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="316" mass="36242" checksum="5339565DDB854A73" modified="2024-05-29" version="1">MQNENPVIYQKKRSKVTNLNEDVVINELEEENIDQEEIFDLIRNINDPEHPLTLEQLNVTQLELINVKGNLISVNFVPTIPHCSMATLIGANIRLSIRVCLLRSLPKRYKIDIHIEKGTHQSEDAVNRQLNDKERVAAALENPHLLKAVNQCLARTAIEIWKFANEKLGGTAMDDKDDSNQIFKSRQLFILTDNSFAFKSIFVIEKIDFGFECTDKILQNLEYEDKTSGVTKCSDVPISCNLGVQLMFVKETERRKGIATKVLSFILKNYYNLSPENPIKNDDNEKEIVAFSQPTKFGRDFAKKFCKKSNFLVYHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVI3</accession>
    <name>A0AAD5TVI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BD-FAE-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000990">
        <property type="protein sequence ID" value="KAJ3208522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVI3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="2">
        <location>
            <begin position="34"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="253" mass="28390" checksum="817AF5B89BF7D11F" modified="2024-05-29" version="1" fragment="single">FWKARHLAKHSDIVYATEQELASAGPGNERLLSLDVYSHEAYPQNCPVIIYVHGNQWVAGDKKNIPPFLQYLVLKKWVVVSINHRLAPQFHFPQHVIDVKRSIRWVRKHISKFGGDPSYICISGSNSGGHLAALTALTANDPYYQPGFTDVDTTVKACIAISSCLDLTNYKSVWSRGFETWFAQTVLGKHTIKGEEEFLSMTSPLSLLKQKLQIRRKSSFNPNLTLVANATNDTSKPHEVTGEDDLVPFLIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVK2</accession>
    <name>A0AAD5TVK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001037">
        <property type="protein sequence ID" value="KAJ3207712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVK2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="132" mass="15078" checksum="CA409C7422C09B08" modified="2024-05-29" version="1">MVEMSILNFRANANDDRLNLSLYIGTTPKFTLYKWVYNFIDSHDVSATTRDANTDYSINIGKTTYTISSNVKFMHHKKSINEDPKEKYKVPVGSEFAAFTQTNIPIILANEGIEEVLVYFRIRTDNNSSPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW75</accession>
    <name>A0AAD5TW75_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007658</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000760">
        <property type="protein sequence ID" value="KAJ3212848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW75"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000032">
        <property type="entry name" value="Krueppel-like factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="174"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3212848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="262" mass="29383" checksum="AC7ACA0E00B7B5BD" modified="2024-05-29" version="1">MNSDQTFTQLVSSFNNNLQQNELQQECTPANSDFDIFSPLINASPSNDAVNYNFLSSPITSTDDVLNIEDYLTEYHPSPASTTISNFDDDLKHYFTNLPPIPEGNLLNIPVNPTVNPQDTITLTYAELAKLMQLAQQGAVSSFTPSNLQQKPAETQSSTLESVKIRSGSQSRTHQCHYPGCQRVFSRAYNLKTHVLTHNKNRPRPYRCDYLGCSKAFVRDADLNRHKGIHNKVKVPNLNCLSCNKTFTRPDALARHKQTCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWC8</accession>
    <name>A0AAD5TWC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000731">
        <property type="protein sequence ID" value="KAJ3213247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWC8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="33456" checksum="9252709506071A59" modified="2024-05-29" version="1">MQEEMKALYFEKNFEVCKAAENIVTIDPNKRDLLYCQDAQGVKFRYTSNQRMVETGSRQRRKKRERLKQASGIDQVESTIPTHKTMILNNYMLYLRQLQLFSNQRQEFYTNSVHNKWKWKTFMNTQQTEQNLIKNMKKKYGNDFVVVMGIGNSVLEKQDYYKTSSLCPFCDGNVEKNFMNRLSSRHWQRRKGKMEIVHGLLGCNNLQCIKQGWARRYWNRDILSTCNMQKIVKSTIIGTGRPAVLSRRPVRFQRANLLSIFRYSCQMVLKTDVKKHIVQALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWG2</accession>
    <name>A0AAD5TWG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000835">
        <property type="protein sequence ID" value="KAJ3211425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWG2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319:SF35">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN PMPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="473" mass="53684" checksum="89C6BBE0CE316AF9" modified="2024-05-29" version="1" fragment="single">AICNGGTDILAMKNFWSDSKLAATRPRLFHCNGASCCDNTDGCKLDDTCIENSSGPLCESCSPGMARWSAECFDCDRPNITYFAILIITVLFVAFFFMFISGYGFSVSGIASMSPSVVINFVSNNFTKCLAPFRGPVIVITAVIFYFCAFFWRNEVKKGNSFILKLHSYLPSRLQNKTMESFNASLLEILLFVFEPLFENAISVFDCRLISLEGENVRVLDSYPDVICYHGSHIPLIILAVILLSLMILFPFFLMRLIYKSRISDIKMLQEEEEIKEGKKIRNSNNSIESLHFIHVIIREYKPQYPYWISADLVIKMTLVTVSVLSSYLGDLVHAHSMFFTLIIYVVLVKNNFYKRDIENNCNVLFSSSLLGVAGIGILQTSHCRFENIVCDNGKIAGFSRLTVWQHIFTFMPLTVLGCRILINCWNLLCQKISQKKKRKLMNRIDVENNIEEKRGKLDTELVVDVTDESSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWG5</accession>
    <name>A0AAD5TWG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-guanine(15) transglycosylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000845">
        <property type="protein sequence ID" value="KAJ3211262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWG5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="1">
        <location>
            <begin position="94"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="281" mass="32338" checksum="A5D3910644AB8E73" modified="2024-05-29" version="1">MELTSTFLKLKNGKKFSTPSLVYNLNGGQINYISKNQINLSNNFTSDHLECFYDCFDVNPLDENTILYLKDYSKNKHLSSSEKFHSIHSQTCHKKLTTKMFFENALKLESKILVSPIALGSLNYWKSQKRNDNFLKELIKLKEDSKLNNKNLNLDLFAVVDGGLDIEKRAMMSFTVFSNFDKDVSGYCLPFFHDLENEDTEEVNFDDKKRNIEPLLSETLKHLPANKPKLALGIRTWRDLQTLLKLGIDLIDTNFFLEKLSKNGVALIIKDVNEVVNVMHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWG6</accession>
    <name>A0AAD5TWG6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CSN8/PSMD8/EIF3K domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000810">
        <property type="protein sequence ID" value="KAJ3211854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWG6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.250">
        <property type="entry name" value="ARM repeat, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009374">
        <property type="entry name" value="eIF3k"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016020">
        <property type="entry name" value="Transl_init_fac_sub12_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSN8/PSMD8/EIF3K" evidence="1">
        <location>
            <begin position="41"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="208" mass="24325" checksum="CE908D3CEC62A76B" modified="2024-05-29" version="1">MNINYIADFEKKVDLMLSSNTYDRRSALHLLKLYQFYPEKLNLKYIEKVLILTLTALPQNDFTLALYLLNEDLHKKEEVQRLINLQLLLETGNFVEFWKELKISKSNSSSNLKNLDKFYPKFNDSVKEFIAKIVNITFENVEKELLKSILNLSDDISLSAFLRNHGWNLNNHTVNIPRPTATQLKVLNNAEGVVQFNQLKKIIEYSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWI8</accession>
    <name>A0AAD5TWI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001342">
        <property type="protein sequence ID" value="KAJ3204090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027706">
        <property type="entry name" value="PGP_Pase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09419">
        <property type="entry name" value="PGP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="115" mass="13099" checksum="7B6BEF20AFB6B2BB" modified="2024-05-29" version="1" fragment="single">MNKLGQSVNISGIKMAFKLLFNPSLAMPHQVLQNFKKVNYKQLKNEGGFSKICFDKDNTLTKPYEMSFVDGEFREIWNQIVKLFGKNNVCIVSNSSGTLDDHNFKEAELVEKSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXA2</accession>
    <name>A0AAD5TXA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_000900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="11">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001228">
        <property type="protein sequence ID" value="KAJ3205162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXA2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000002">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="12">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="13">
        <location>
            <begin position="248"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3205162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="450" mass="50098" checksum="503D6B4C86D4A37B" modified="2024-05-29" version="1">MRECISVHIGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRTVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADNCTGLQGFLVFHSFGGGTGSGFGALLLERLSVDYGKKSKLEFSVYPAPQVSTAVVEPYNSILCTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIAQVVSSITASLRFDGSLNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLTVAEITYSCFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSVEGEEEEAEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXF0</accession>
    <name>A0AAD5TXF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000587">
        <property type="protein sequence ID" value="KAJ3214848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXF0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="112" mass="12676" checksum="6468E274C2DCDEF7" modified="2024-05-29" version="1">MNCTLRYLRLAANNHELAANNHELAANNYELAANNHKLAANNHELAANNHELMKLRLITKYRCKKLTITTTFAADNASRFATDQRLFYQGIFKGILFCEGGFVKTPSNTDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXR0</accession>
    <name>A0AAD5TXR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002333</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001766">
        <property type="protein sequence ID" value="KAJ3201209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXR0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000032">
        <property type="entry name" value="Krueppel-like factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="361"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="391"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="420"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="29"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3201209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="451" mass="51053" checksum="62B3052007553058" modified="2024-05-29" version="1">MEILSDFGINGCFNNNSYSNNSYDDNNANNSFVDNVNNSYPDNVNNSFPDNVNNTYPENVNNTYSENVNNAYPDNSNNSYVDNSNNSYVDNSNNSYVDNSNNSYVDNSNNSYVDNSNNSFAENSYADNSNNHSFVDNPNGINNSTNYSNTLSNSYHNNDVFNSSHLLKNSTNLPNSPQSLADESYPNSPHSSYLDSLYHLQSSAINPHSSKIPSHYHLVDSPYMAYNDFPNNYTQSPYNSPVNSPLVLPSLSQVFPNEYSSPDSSPVDNSHYNPINNFTSDNKEYLQFHPIDYQNSYHPNDYHKQLDSYSTIVASTDFNNIQNLNSNLQHSSSLTKKLTSPTKKKKVKSITNNTEENLEILKCPYQDCPKTFTKQFNLKSHLRSHTVDKNFSCDSCSVSFRRSHDLKRHIRSLHSAVKAYACPTCDKRFARTDALKRHCSRPQTACNPNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY68</accession>
    <name>A0AAD5TY68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000524">
        <property type="protein sequence ID" value="KAJ3215727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY68"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="369" mass="38183" checksum="F1877CD219FF3FDB" modified="2024-05-29" version="1">MPKVEVFCGVPKVVEAEDGALKVAEPKAGVVVEPKAGVVDSNAGVEDPKVEVVDTNAGAVVETNEFAVPNAGVEEDPNRVAVVVADDPKVVVEVPPKAGVLIDPGVSVGLDPKTVALLDPPKAGLVLDPRVEVASDPKAGVVIDPKAGAVLDPKAGAVLDPKADVTFDPKAGVVLDPKADVVFVPKAGVLLDPKVGAALDPKAEEVLDRKADEVLDPNADEVFDPKAEVAADPKEGGVLVDIPNGREELAPKLEVFPKPLVPNVGADDPKELLPKAGAVAPPNDGVEGADVPKLPKAGIILDPKLEFDDVAKAPTAPALLVLSDVIADPKALELGLKEELPKLLVFPKAEFIPKAPVEDPKELVFFKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYH1</accession>
    <name>A0AAD5TYH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nuclear cap-binding protein subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NCBP1</name>
        <name evidence="11" type="ORF">HK099_007888</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NCBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000808">
        <property type="protein sequence ID" value="KAJ3211882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYH1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027159">
        <property type="entry name" value="CBP80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015172">
        <property type="entry name" value="MIF4G-like_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015174">
        <property type="entry name" value="MIF4G-like_typ-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412">
        <property type="entry name" value="CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412:SF2">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09088">
        <property type="entry name" value="MIF4G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09090">
        <property type="entry name" value="MIF4G_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="MIF4G" evidence="8">
        <location>
            <begin position="111"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G-like type 1" evidence="9">
        <location>
            <begin position="331"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G-like type 2" evidence="10">
        <location>
            <begin position="510"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="913"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="1121"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3211882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1152" mass="132956" checksum="4AC3BB08A410D7C1" modified="2024-05-29" version="1">MSGYHRGDSRGRYRGSRGKTYNSTKPYYKRPTQDRNQTYNLKTEEDPVGQNKLIRPFKDLGETTNLNANLAYVTTQVIKEWQINQNDVLTVFTICITQLPFKLVYYAQLLSQINKENTQIAQDILSHLVRFFGFLVNSHAITALSLFQVYNQLLSQLQSENQNPSKKLDLMMDQNVYIVLASLPFIGKILFEQAQKDLKQLLATIETYMNNRKAYPDGSDEMHIESDSHSNSLSIEILNNYRDGNQGFDKVDVLTELWLTILKLQSNNWEVDVLFKPHKIYMDNITQPKLNLRNLATVPDFPDFTYAYQGPVFHIYTSDTESKLNIKHHLPDIHHISRFIMSDSAREIIHLFSHNHKECIRYLLSLSKFHLVLDTDEDGKAAVFEIILETIFTEMLKFPKSKEKTIYYMVLVAGLCKGAPTLFPSALGKAVKILFLRLDDQEYPAGGMDVASIKTEYALSLSPSTGRHSFLCQLMDSCVRLSYIDHIKVKLPQSFVDSNVFDKEGPRVNFKFADKETTGNEEFHSLMQDLEYTLKSSMRESVLKNLEENFILIRNFLNLNPEFKCKFYFQDIDSILLECLIQCLMISGSKSFSHLLNSFERNLPALKAYMSTTNSSQSSEKTIKSIHIISEFWKYNTQAFELSLNKLQNYLILDPQSVLLWVLKKVSFDLKFGGCQTLFEESNTAGGDFWGGEECFYQSLYWNLLFSTLAKVNLRCDQCFIKLEECKKSEDMSKFSDLSRNYEGASRDRKVAFQFVLAKFCEIISQKSSIMESSGVDIKLTDWWRWVVGNMREVLRRFDSTIKTFKVTLDINVFSDNKDPKVLKIWSEACEMYERRVEFKNSMIKEIKPNLTCLSTPITRESVSYHINCENYNKEIVDLNFSDFIQDQFYFVSACMGGTASLRSKDGDWIGSYIGHRSSVLSSKISRDAVFSVTGSLDCTTKVWQNNSGEMLLSFDNYAAVKIVDISFDNKFVLTSGSENKIKIYDLGSQRKKPLRILDFGISGEIKSVLFDSENGLILNIDGKELKLWDLKSSKIISKVKFDNNLTNLKFSQDKDYIMLSELKKLHFFKLKSAELVKTFTFDFIIQSYDYKEKLRKLIVSFENLFEVFVYDWEENEIDIKIGHCGKINAVSFTPDDRFASASNDKTIKIWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYJ3</accession>
    <name>A0AAD5TYJ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000520">
        <property type="protein sequence ID" value="KAJ3215791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYJ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="313" mass="33924" checksum="1AB1A3EB1C069B5A" modified="2024-05-29" version="1" fragment="single">AANNPHQNLKKAILIRRQRGNDVSSDNLGNPSQDPPKVEEPEPSPEPPKPTTDLSTPTNPEPTVSPKPEPTIDPTKTSLSPTIAPPNTNPSTTSTQLASPTIPRTTKSKPHTSSAPTNPIVNPSSSSANSIIASLSNSLFVTDPTTTFSPGLNNSSAADDFTGEKTNGLSTASVWAIATVAVCVVGAVIGIWIFRKWKLRPSDKFAIRMRTNPFKKNNNNLSSDRVTVSTYNGDNTTNNNYQNSEWGGYQNSDRGGVNTVLASNGYQRSECGYSDMQNNFQLNNNQVPMNYVPINYYNPTTHSNYNNNSYNGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYP1</accession>
    <name>A0AAD5TYP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA (cytosine(38)-C(5))-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.204</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">DNA (cytosine-5)-methyltransferase-like protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TRDMT1</name>
        <name evidence="8" type="ORF">HK099_006106</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.204" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000505">
        <property type="protein sequence ID" value="KAJ3215996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYP1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050750">
        <property type="entry name" value="C5-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098:SF1">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3215996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="393" mass="45981" checksum="5DFCD0EE41C0FFB6" modified="2024-05-29" version="1">MNCVLPFDMMELKCLEFFSGIGGMHYALQKSNLIGKVLESFDINPTANLTYEYNFNVKPNQISIEMLKVDYIEKLSANTWLLSPPCQPFTQGGLRKDSKDIRCTALFHLFEKLLPNLNNKPEYIFIENVANFAHSDAKSRILKVLRKNYQFFEFILSPLQFNIPNDRNRYYLLARKNSISVSQLQYKDSDIILDWHLKKNENDINTLSNYQLEENLDEFLVPSKMFKNRKTFSVGVIVKPSDTYSFCFTKAYGRHGVGSGSYLQTLNLNLDPIAYYKEFVYKEDETILLENNMLNQFNKKSSKKETDTEKLENFIKMFGIRYFSPLEVCYLNGFPIKSESFFQEKTLFKFNTSKTNKNQNWRMIGNSLNVTVVSELLKVLVVDDMFWERNKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYV5</accession>
    <name>A0AAD5TYV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000422">
        <property type="protein sequence ID" value="KAJ3217544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYV5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="52" mass="5929" checksum="DB08FA2CDFC74219" modified="2024-05-29" version="1" fragment="single">MTEKNVVDFIVAIAQKAKSKGDLNKKLLQVDLPENEKTKAFAQQLFDKIPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ02</accession>
    <name>A0AAD5TZ02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000872</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001219">
        <property type="protein sequence ID" value="KAJ3205268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ02"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000720">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="62"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3205268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="84" mass="9964" checksum="67848B2FBCBC7CA5" modified="2024-05-29" version="1" fragment="single">MFWVPYFASNVTAIIFIAAISSYDQFMEEEPETNRLVDSLKLFTDVCNHKLLKESSMILFLNKYDLFIQKITYSSINKYFPEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ19</accession>
    <name>A0AAD5TZ19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000429">
        <property type="protein sequence ID" value="KAJ3217387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ19"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="6"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="280" mass="30740" checksum="83D4BFA53F4830D2" modified="2024-05-29" version="1">MSCQTALITANSSDTCFSIASSLGIPLNEFITNSNIDCENIQQGQKICPRVITNTVSLTSTLISTNSFSGTSITPTTTIPTTVSSSVQLSSTTTTSVPLNTSTAPNVTNNSPFSIFNTSQTNTIIILSICSAALFLTILVCICICCKKRKASIKRKKLDNERRLRNNKNLAENYGIRSRTSGLKSSSYIAPSELTFANDSRASSLYPSHSISQIGVPQNFNYNPEDYENLKNMKPGNLTYPNQVLYDQNYNYANFNDKYNNGSLIRDENVGKLYSMYAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ86</accession>
    <name>A0AAD5TZ86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA synthetase member 3, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ACSF3</name>
        <name evidence="4" type="ORF">HK099_005453</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000424">
        <property type="protein sequence ID" value="KAJ3217505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ86"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05941">
        <property type="entry name" value="MCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF8">
        <property type="entry name" value="ACYL-COA SYNTHETASE FAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="68"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="447"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="534" mass="60402" checksum="BE49A05DEBEA73E5" modified="2024-05-29" version="1">MRIHQSYLHKLKRLDVYNAMIENLKKPAVISSHNNVSDTTDFQTVLIKSKELSRRIEKEIGGVGFKNEPSKRISVLSHPDKNFIISLLSTWDTGNCFVPLCTSHPAKELKYIIENSDSKLILYHSCFKNKINELKLEIEDNNQIKYLQLDSNTKSDLVGVEEETFEISSKNFDKSLAAVIIYTSGTTGKPKGVVLTHLNIEAQIRSLQSAWGWEKDDKILNVLPLHHVHGLINVVFCALFTGASLEMNNGFKAIDVWKRFNTESQDLTLFMAVPTIYSKLIEEFHKMSKDDQIKSKNSLRQFRLMVSGSAALPEKIFEKWEAISGHKLLERYGMTEIGMVLGNPLIGERTSGEVGVPFPGVKLKILSDEGIDITNDCNKNGQLLVKGDQISVGYWNNSKANFESFDSEGYFKTGDIVKRGDNGRFKILGRASVDVIKIGGYKVSALEIEREILEMDNVKECSVFGKFDEVYGEKIICLVVLQNETLKFDLTQMRKFLQDKLAPYKIPQVLLVLKEIPKNIMGKVNKKELKKLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ91</accession>
    <name>A0AAD5TZ91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alginate lyase 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000401">
        <property type="protein sequence ID" value="KAJ3217972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ91"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042159156" description="Alginate lyase 2 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase 2" evidence="2">
        <location>
            <begin position="48"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="301" mass="33314" checksum="B8473B71308FE54A" modified="2024-05-29" version="1" fragment="single">MFITCCNRFNFMLYTLFLAAIITSASKKSVPIPASSFAKSDNPLRQPFSLHNWTLQLPIGVGSDFETVRNPLLSEPGYGNDFFHLNKPGNAYVFHTPVLPENGVSSENSAFTRTELREMNHTNNKLEASWDTVKGVHYMKVTQSINSISSSTEGKLINFQIHSDCCAVLTVRLFSKPETGVLLFADFDKFANGSLTKIIGADKYPLIENYVLGTIFDLEVVVDNGLVYVYLNGVLKSPKEGYRSNLLAVYFKAGSYSQNVPSATIPATAVNEVSIYKMELYHGDGPYTPPTPSNPTIDSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZQ8</accession>
    <name>A0AAD5TZQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000587">
        <property type="protein sequence ID" value="KAJ3214850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZQ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="336"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="407" mass="46830" checksum="9F2E7B217D982BD1" modified="2024-05-29" version="1">MAQIWLSEYQRAFCINKPLVHIEEEVALFPNQNEKEIVRITDDDKFIEKKFYTLPEKEVVTEVTIEKPLKDTTKDKRIERDILNYGYGNVNPVLPSNYMKSYNVTVPKDQVMPLTEARVLNSKNYDAKLNYPKKKLKESLKEYQKAASILDKLTNRFQSEYSLQFLDWSKVKDRPASRVEEEVVLQKENYAPKNIIRPVEVTPVNVTSDLPVRTYESSLQNSPVFKPSTIKQSNSSSVQTSPVLAPSSPTILHSPARSSPSRVGFKDTVSVVPKGVPESNIFPTDEGTVLNTLNASTNPFQYSGDSLYPLAEKLVSPQQNNLHLGHSEKRHFPYKNDFLTLQLKELNKNLKLNEEKMLKELKNVKIENFRDDGFVGDRKGKIFKNRDREYNDLAKDILLRANKRLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZZ2</accession>
    <name>A0AAD5TZZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000592">
        <property type="protein sequence ID" value="KAJ3214785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZZ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="229" mass="26483" checksum="F88254316A2D7972" modified="2024-05-29" version="1">MSLQIPIQYNKNKPLQVDNKNLESTTSTSIIKPQDLKFNLSIIDSSIRNFTKSYFPRRLFYIISAVLFFTMFAALSAKSYVNYLDLLAAYETLPPSQQLPDSLDYVERPTFNYVKLLIYIFLGLVVNPLLNISFYNEKLVKFQSTFEIELKKVLYNISMQSYISGCYYVLVAENPIVNTVKKNVFSKFKLIKFHILVTPAEEIDISIPPPAFSQHDTENYNYPPTYSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U025</accession>
    <name>A0AAD5U025_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutathione synthetase</fullName>
            <shortName evidence="9">GSH-S</shortName>
            <ecNumber evidence="9">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_005613</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9 11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000446">
        <property type="protein sequence ID" value="KAJ3217057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U025"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.50:FF:000002">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="entry name" value="Glutathione synthase, substrate-binding domain superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="entry name" value="Glutathione Synthetase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01986">
        <property type="entry name" value="glut_syn_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130:SF0">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione synthase substrate-binding" evidence="12">
        <location>
            <begin position="215"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="390"/>
            <end position="393"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3217057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="471" mass="53096" checksum="F292EC0113915D66" modified="2024-05-29" version="1">MSDYPLLTEKAINHLKFLSEDYALAHGLVMRHPTVSSAIIHAPFTLFPSAYPKSCFQNAIDIQKIFNKLIDKLSRDDKLIRNVMEELSIADDFMKKTYEIYKKVADKPSVQTITLGLHRSDYLIHMEVSNENSKPKPVLQQVELNTIAASFSSLSTRVSELHQFLAKSGNYVESDVQQKTKFDFDYNNMPINNSIEAIPKGLAEAWKLYKYKQGVVMMIVQPNERNSFDQRQIEYKLNEKYGVQLIRKTLKEVFDSAKIVNGELMIDNKIVCVTSARLLIEESRTVKCPNIQYHIVGSKKIQQILATPGVVERYLEDPAEVKLIRSCFTGLYPLDNSMEGKEAIKKALATPEKFVMKPQREGGGNNVYGLDIPPVISKLNELELNGYILMDLIQTPDMSNVMVKQGEISVKPVISELGIYGVWVSDENEVYINEDCGHLVRTKNVGVTEGGVATGFSVLDSPLLVEDALFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U037</accession>
    <name>A0AAD5U037_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ectopic P granules protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EPG5</name>
        <name evidence="5" type="ORF">HK099_004835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EPG5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000354">
        <property type="protein sequence ID" value="KAJ3219052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051436">
        <property type="entry name" value="Autophagy-related_EPG5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058750">
        <property type="entry name" value="TPR_Epg5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31139">
        <property type="entry name" value="ECTOPIC P GRANULES PROTEIN 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31139:SF4">
        <property type="entry name" value="ECTOPIC P GRANULES PROTEIN 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26573">
        <property type="entry name" value="TPR_Epg5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epg5-like TPR" evidence="4">
        <location>
            <begin position="1361"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3219052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2677" mass="309855" checksum="3F95CFEF5038515F" modified="2024-05-29" version="1">MEMEVEVKVKHKKTKKTKTSKAKEIPKFETAATEVNDAVENQVDNQKKETITEEDYEVNPLINIHQTMSLTVCEQSLLYPKLDLPSLSSVDNKISFLKSITSEQQVHLPSIDDLICNDQIKTECEAQKAMQNLDMNFSEFYNLDSAKIRNPSSAELLNFVFPTFRIDEQVEISEQFLLDSTNLWEFNDDFYKKLLEYEHYFFTVQNLKVKLSSLQSNALDLSSKVWTLKKESLQVQENCKDGVSLIHSFTSEEALFNFKYYSELKSKFEEIRIFYYEKLVNSLFESKICKIYIQNLIDSTLEKNDSDLTLTKVKKYLDILFHCEKKLFCQKNSLELENFGILLKELRGWISTIVGFLLKSFGMKENMFILLHCLRTSHISKWGAGFIQWPISSLNIFSLSSHYITENKTVCGHYIACLQLLMSPLLGRYIEIFSNQNYYIHCQIEKDKDRVNFEVQKEHTKESLRSEVDWFVVDEDDLREELELEKPIFDLVSLSDEDYCQLFIQFNFEEVLEIILSKFTEYWLKFCQKNFTHEIANSEEKKNFEIETELFKTLSVVYQFLEIFSRAYNSFPHSKYPKFVDTITSSLTMMIDKFCTSLHEVDLENYTFSSRPIFFINNYIQIEVGEFHEVTSMQMEIDSMVLKSIKVILRFENCVLWKNLLSLPVNLLSIKGKWDCFMALFSQSIEEGKKNCINLRNGDASRIWGLLWQKIDYSPFVLEFLGELAIKCDAHTTNIQDSFRETGAGIAHMTWKDVMYSPDSTSFFDLVIEITKYIFLFCYGGDKWKPLTKPMFYGKKKPKLKIPNAVLISVETVLFKLASNFPQLMSWIFGWTREILSENLLSPVQKLALIKLIYVLPLKLWNPTLVDLEMALGMLKEMGTDEVKFVIGKAILENLNWSSLKRSSHRDVALTLFNICLDKGCISEIRDPNNTTGLLGKVGNVAYETINGAIGFASETIEAGTEFSINALESISSNTLKWSWSKSNYEEDSIELNMDPSLLMKLNEPQFSTWCWYHTKKGKFIFGIINFIFKFVRNLYQKLNLYHSPNSSNAYSILSEDLSLEKPFDSLTNPHFAMVRGAMFTNPMGAYLALMTSEIGHSIHMFSTDGWKLLNLLKSAGQYFEIFQITSKVFPTLISFSISNLETLTADEKFSLFWKDFWDLVPLKERFFSLERNKNDRSLEIVHKVFSDHYMKFQTTLEREFYTKYWLAVLTCNDLQWFTNRAKIRVFDMFCEAAVKFHLSYLQQCESVTKSMVELVEIQFEESLSNASSGTSKILPFIEKVYKQQVELSTIIMGSSLHSVEFSKSLGPLALNITGKIERECVWFSFLALRVETMLETEIRQDIGRYCIQNSKTLEEALIKKFGSSTVQGFTIVKWVGHLVNIPHCHPLAVLYAQMFFSLYFEKCDPPAMATDARFGFKFISEHYGVLKQLENYLSMSQQYYAKKIDFLKPNSIPNQLYKLFNAMLLWLRNPLLCNSAHIDPISLPESYDVERLTSCLNSACLKKKCFQGDRFDGVWLDLFPFQVCVDNVLLPVVGNVDSTNEKKKENEKESLNNHVRYFSKTSPPVFTPKKLYIPTVNSLNFEIVKDTLNLSKEYKSDFSILLTKSKIFQSVVTKNMELDYEYLKHIKNLYVNETKVGQTKKNCSSIAMTVSNALHPLVGNDRRSCKGPAIFDFEYKSVSVVNQWKVFLDGNRYDVSSLLVNEQVDHSVCVSLLRLLNSVQWLIENWALPKIADFSIEIFYKLIEIMTTTDSEEFHDGYDDTSDFNFNTQLENFPALYSFLEALFTGIGNTFIINSKKESFRLKEFFLAQKTKFSSQNSVKRSTLMILAKVYNPAVICSDTASFTSDYLQFLNLRSSFGSEVTSALIQRFDINQFKKFNNDNENVSKFLEAVLESFQISIAERPFTEFDSVIFSDFLFSLSSALNALLKSDFNLAITVVLNKLCHSKIPIEVTYVLAAEITNVNISELCTACYIEKTVDNLKFFETNDVSLQFVLNIPKLITSEVFQHQVERFHNGLKVDDLLHTFIPLLDLTCICFLCKPLYMISPIFQFEVINLITNTLKFFLEALTLPIYKKKEEWNSIVKKVVKAFVLVTNKLTICWNVTEQLPIIIWNWIEVFLNTFQNADITIPILETLALFPEIWNSFYINEKVIFQILQCAEMNDIWKMRHLRRFFCWLLTKAHWNLLQTCEENVDLENSPTNSILHIIFLLLVDIDVFFNNFETEKQDFMKTLFSKLKDVETKNYSPSEFEKLLNLIQVDAIQGELTSIFANDGIISFEFIIEFARNFINVPTLEDFNKESLQIKLTPNQLELTRVLIFFILKVLLYQIDNKHLNRSYIEPASIGFIISEILEFLEIIVPQEPHLGLEILNQTFQKVLNLENRCVVGTAVSTQIWNGIKNFATLSNHSLSIIYLACHILSSVEQIALLVEISIERYFNFNPGASQQNWKVVLEVVAVPELDEDIFVRHCLNHALILTLHVHFLQKLQNCKKPEQKVLMGEQLGIWIPSINVSSFSSANDSLQGEKKMVLMLKQYAELLKEELDSLGLPITHSRLRSHLPRIGENLTRLTGDKENTGLWATLGYGPKSKLSMKFRIVSTFIATKLLINPDDDWDMLDTVSDDFSKLLTKIKDLSSNKEYEPIYSLLDTFTNFITDKSLSIANLLDLITLFQDLIPEYQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0T1</accession>
    <name>A0AAD5U0T1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Intraflagellar transport protein 122 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_004014</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000273">
        <property type="protein sequence ID" value="KAJ3220794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0T1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000005">
        <property type="entry name" value="Intraflagellar transport protein 122 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056153">
        <property type="entry name" value="Beta-prop_IFT122_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056152">
        <property type="entry name" value="Beta-prop_IFT122_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039857">
        <property type="entry name" value="Ift122/121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057411">
        <property type="entry name" value="TPR_IFT122"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056838">
        <property type="entry name" value="Zn_ribbon_IFT122"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764:SF4">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764">
        <property type="entry name" value="WD REPEAT DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23381">
        <property type="entry name" value="Beta-prop_IFT122_1st"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23377">
        <property type="entry name" value="Beta-prop_IFT122_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25295">
        <property type="entry name" value="TPR_IFT122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25144">
        <property type="entry name" value="Zn_ribbon_IFT122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT122 first beta-propeller" evidence="10">
        <location>
            <begin position="2"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="54"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="IFT122 first beta-propeller" evidence="10">
        <location>
            <begin position="191"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="IFT122 second beta-propeller" evidence="9">
        <location>
            <begin position="301"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Intraflagellar transport protein 122 homolog TPR" evidence="12">
        <location>
            <begin position="563"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="domain" description="IFT122 zinc ribbon" evidence="11">
        <location>
            <begin position="1005"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1069"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1069"/>
            <end position="1086"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3220794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1217" mass="139058" checksum="03C23362F644F347" modified="2024-05-29" version="1">MRSFLTWSDKVQDQNGVRQPIWDLSFHPDGTQLIVTAGSEILVYSIEGELIQSLKSHKNTVYCVDYSIDGARFVSGSADKNVIIWNAITREGILKYSHNDPIQAIAHNPVTDQVLSCSASDFGIWSSESKNVNKVKVNSRILTAAWCSNGQSFALGLYNGVVSIRTKSGEETVKIDRGKNIPVWAISWNKNPEKDNDIIAVTDWNQKLSFFQPNGKQIGKERHLGFDPCSVSFSYDTEYLVVGGSDKKVQLWTPEGIKIGLVCEKDQWIWCCKVKPKQNYVAVGCNDGTISIYQLVFNTVHGLFNDRYAFRENLTDVVIQHLVTDQRARIKCRDHVKKISVYKDRLAVQLPDRIIVYELFHDDATDMHYRIREKIPKKLDCNLLVVTSLHIILCKEKTLQMFNFSGEKEREWNLDAVIRYIKVFGGSPGREGLLVGLKNGHILQIFLDNHFPMLLMKQSTAVRCLDINLARNKLAVVDDQNTCLVYDLDLKDLIYQEPNANSVAWNTEMEDILCFAGNGTLNVKAGMFPAQQQKMPGFVVGFKGARVFSLQTRNMSVVDVPYSLMLERYMEKGDFVDAYKLACLGATEGDWRKLALESLQGLNWEISKKCFIRLRELKFIDLIQTFENAKAEGVNEDVNSCLAEILALSEKYHEAAKFYKQAGNFQKAIDMYTQLNMWDFATKIALESDISPTEILKMKAKMQFERNDLLAAAATYTEVGMFNEAIDILGPNGWLDNLIEVARKLNKSETKALSRCVYFFKNHNHHSYAAECLVKMGDIQNLLKLHIELLHWDEAFRLAETRPQFNSEIFLPYANWLAMNDRFVEAQLNYQKAGRLDVAFRVLQQLTQNAISEKRYEDGAYYFWTLSMQHCDSLPSDVELEALTVAQRKTLEDFHTYYELSEVYYAYHFVQRYMDEPFTSHLTESLFNMALFVLDYLNKKPAPQGVSRVYVLFALAKLSRVLGAFKTARYAYETLQSCVIPSDWVDLIELGTMTVRSKPTNDRQELMPVCYGCGTLHPLTTATTNTEFRCTYCLEPFIHSFYSFDTLPLVQFVLEPDINPEEAQRLINTPKPTANIPGSKNRPTTSKSKRMTKEVRGDQSEENGGLAGNVNGFALRDDDPFNRALLALERDKTGKHIPVVLNRKEILSLGKHLVFVKKWGKKCLPDQYYCHIQSNDNHDVGIKLCNSCNHFFFDDEWCYQLLQKGVCPFCRVPQELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0T9</accession>
    <name>A0AAD5U0T9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000494">
        <property type="protein sequence ID" value="KAJ3216161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0T9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="101" mass="11962" checksum="25E768D71144774C" modified="2024-05-29" version="1">MDFDKIVEVVRIGINEYNKVNNNPLGYNETITVFYLKLIEKNLKSLLAVTDTRFISLHDIEFEDFLKTFPEILDKNLIFQFYSSKNLIEKLKYVPPDLKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U129</accession>
    <name>A0AAD5U129_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nuclear speckle splicing regulatory protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004104</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000281">
        <property type="protein sequence ID" value="KAJ3220679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U129"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053246">
        <property type="entry name" value="NS_splicing_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018612">
        <property type="entry name" value="NSRP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845:SF1">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09745">
        <property type="entry name" value="NSRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear speckle splicing regulatory protein 1 N-terminal" evidence="5">
        <location>
            <begin position="82"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="172"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="273"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="383" mass="45189" checksum="B5148341555B41D4" modified="2024-05-29" version="1">MFNKKKIPLTFGINVKSKNDNLKNLPTQKKSIIDTKDRVDLGGESSSSSSDEDKSDTKDVIIKRANKQINTSSSLKEELLVIQNAQEEDPDIFDYDKSYDRTKLLQETKKKLKRGELDQNGRLKPRYIENIKKASEQRKLDYELAEEKKIERERKQENGLFDEKEKFVTDNYKKLQLERELLKKKEENEEAKIDMNGFYKGILQDFDRDNDVSIVSKAEEALLKEKLRLDQEEEEILKGKIEENTNIKVNDSNEVVDKSKLLKGGLNISKKKIIQIQREEEVFKEEIKKLKLKEQEEARLREEEFLKRRKLKAERIRQSMLLKQQQQEVDLKEKKLKEEDLQDFKANLKRKVDEVGLLSAKERYLQRKKLMDVKKEESSSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1D8</accession>
    <name>A0AAD5U1D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ran GTPase-activating protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004772</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000348">
        <property type="protein sequence ID" value="KAJ3219227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1D8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00116">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="337"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3219227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="42492" checksum="AD42AE80303582C4" modified="2024-05-29" version="1">MTSPDKIFSIQGRTLTLDTADDVKEFCDQIANFKDLEEVRFFQNTLGIEACRALSKAIKLHKTLKVANLSDMFTRRKEDVIPVCLEAFVDALIDQPNLVEIDLSDNAFGPICAEPLMRLITQNRNIQTIKLNNNGLGIGGSEYISKALIEAAELNKKENKQSNLRTFVVGRNRMENQGAANFARAFERHTGLIEVRMPQNSIRAEGIEILVNSLGCCKSLEVLDLQDNTFTLKGSIATAKALQNWKSLRVLNIGECLLGAEGSKEIIKALTGSHNNLTTILLSYNELDYASAKLLPDMLEDKMYLEKLELNGNAFEADSKEVQDIKDILRGLGQEDALDELDDMEVPSDDEQEEEESESEEKSSDKNLEDLTDLASKLKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1K3</accession>
    <name>A0AAD5U1K3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">EMC1</name>
        <name evidence="15" type="ORF">HK099_003497</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000229">
        <property type="protein sequence ID" value="KAJ3221454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1K3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058545">
        <property type="entry name" value="Beta-prop_EMC1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25293">
        <property type="entry name" value="Beta-prop_EMC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041959228" description="ER membrane protein complex subunit 1" evidence="12">
        <location>
            <begin position="22"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="domain" description="EMC1 first beta-propeller" evidence="14">
        <location>
            <begin position="22"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="13">
        <location>
            <begin position="799"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="750"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="758"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="768"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3221454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="995" mass="111710" checksum="3F73B457F683642A" modified="2024-05-29" version="1">MRLIYFNSYLIYFILLNLSVGLFEDQTGLADWHKTLIGTAKFINYDRSNKKTKLIVSTNKNVIASLNHKDGSILWRQHLDEQDIILKTATTDDDMKLYPNGEVLSLVNNQVQRYGKSGNIIWTWTNKSVSIHHIFGSSKKLVVLGTSQAEDYELKYFTLNPVMGTPIADERLLDTFKYDPSETKLLDVQNEKELWIVWSNVNLIFAKNVDGNAEKVVLKASLEEVTIRKLSASHFSLTTKGSIQLFDLRNGEIVTELEFSINENDKVNHALTAIKDKYYFAKIITSEQNAQIEVFEVGSKNPLYNIQVTNPFEGGNALEIAQLVLFNTESTGLRLVMSGNDGLIKMYKGEAILWIREEYLTEIATAEFIELPKAGLFSEEHDELNESVEETEKISPLTRYFRRWSSQLLKLQAYLKAGNLLFKSEETSETNNFFRDAFGFKKLIVFATKRGMIVAIDTLSGDVAWRRYVGASTMEVKQLSLVRSSVIKFPPVILIVAENTKETVLRRLNAITGADYTFGDIPSSVKLPFLATQVFKLPIEESSDRTHIFAILSPDLKVMSSFYFILLNANVQVYLFPDTPESFSAVEEKLSFLNFYLTEGPGSKSIAGYSLIKDGNFASVKNWEYLTEESEVIAALATIGDNKVSSLGRVLGDRSVYYKYLSPNFLSFVTLKTSESSKLILSINVVDTVTGSLLYSGAVDGAGLLDLDTDIANFGGASSSVYITQFENRVVATYFNHGPEFADVEDETVVPPQNQNLGKEKVTEEKPRRKSKNVKQRKVKGGAELPTSEAASENLVTPNTKQMELLVLEIFEDFKPNVRLTNETFSSHERGNPHVLAQTFSFSHGVSSIGVTQTHNSITTREIIFALGSDQIYCLNKRILDPRRPLVPSNFDKEEMLIPYKAHIDFNPKEVASYNLAVIGVEKIISSPSALESTSLICSYGLDIFFTRRTPSQAFDVLSEDFNRGGLILTIVLLLIAIQVSKKKVDHKTLVEAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1X9</accession>
    <name>A0AAD5U1X9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004812</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000351">
        <property type="protein sequence ID" value="KAJ3219118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1X9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11380">
        <property type="entry name" value="Ribosomal_S8e_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.168.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.70:FF:000009">
        <property type="entry name" value="40S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.168.20">
        <property type="entry name" value="Ribosomal protein S8e, subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_eS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018283">
        <property type="entry name" value="Ribosomal_eS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042563">
        <property type="entry name" value="Ribosomal_protein_eS8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01193">
        <property type="entry name" value="RIBOSOMAL_S8E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="206" mass="23511" checksum="C4C5A3788FFE8F3E" modified="2024-05-29" version="1">MGISRDSRHKRSHTGAKRAQYRKKRKFELGRQSANTKIGAKRVHVVRVRGGNLKYRALRLDSGNFSWGSESISKKARIIKVVYNSTNNELVRTNTLVKGCIVEIDAAPFRQWYESHYALPLGKKSKKAAAEKGVVDPLDRKKSKHVERKIAARKENSHVEQHLEDQFSTGRIYARIASRPGQAGRADGVILEGKELDFYMRKLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2H7</accession>
    <name>A0AAD5U2H7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000187">
        <property type="protein sequence ID" value="KAJ3222181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2H7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033362">
        <property type="entry name" value="SSNA1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28661:SF1">
        <property type="entry name" value="MICROTUBULE NUCLEATION FACTOR SSNA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28661">
        <property type="entry name" value="SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="105" mass="12278" checksum="594B8CD14F500F9B" modified="2024-05-29" version="1">MSSLQILNTDLVKGLNELKKGKDEIEKKINLDKEKKSTLEKEKKELELKLSFLESSLKKKQLIFDKYCDLINETEKNYSMIVQSSKNLLDVLKKEKTEIETNEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2L2</accession>
    <name>A0AAD5U2L2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000294">
        <property type="protein sequence ID" value="KAJ3220524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2L2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF62">
        <property type="entry name" value="ACYL-COA BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="3">
        <location>
            <begin position="2"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="85" mass="9368" checksum="4C3FD9DFC62A4A5A" modified="2024-05-29" version="1">MSNAEFIKAAADVKNLKTKPNNDQLLSLYAHFKQSIVGDNNTDRPGMFDLQGKAKWDAWNAIKGLSKADAQAKYIEIVKGLQASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Q5</accession>
    <name>A0AAD5U2Q5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Copine-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CPNE7</name>
        <name evidence="2" type="ORF">HK099_002344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000177">
        <property type="protein sequence ID" value="KAJ3222400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Q5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="323" mass="37406" checksum="32FB9B9B883A2B25" modified="2024-05-29" version="1">MYFKILNLYPRDENSLVLSFPMVMLHKKVYNPLTKSYDWDKKPQKTEVLQNTLNPVFEKMFSIDYVFSEKLELKFLVVDVHGYEYLEDSEDHDFLGSVEITLDEIVYEKKPVTLPLKYGSFQNLGVIKIAPFAKKLHDKIDLTLAFHAILEKPIFNKINTFFTIHRSNLLDKNFELLHESDVISKCFKPVSPNLELNLANVLKEADSEEDCLLKFEVFQQKLVGNAEFMGCFQTTLNELITNKGRALEFELINERKRVAKSGNKSGVVSSYKNSGIFNVSCIKYDQYTSFFDYVYNGLKLNAGFAIDLRINGKIIKKRIKVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U329</accession>
    <name>A0AAD5U329_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptide hydrolase</fullName>
            <ecNumber evidence="9">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LAP1_2</name>
        <name evidence="11" type="ORF">HK099_003813</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000256">
        <property type="protein sequence ID" value="KAJ3221035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U329"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041775089" description="Peptide hydrolase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="10">
        <location>
            <begin position="161"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="371" mass="40753" checksum="1C6BC394CB53EF2A" modified="2024-05-29" version="1">MKLNLFTLVTLIASTFAIPVGEKPENANLRRISTKEGESQWMTEDEIAVLIRDVIPFIDLTDEVPTNNFRPAPRPIRANPSTPTQQSLVKPLTEQIDLQQMKDFLTTFSTFNNRYYKSTSGKESSIWLQGQLEAVAKYSNSTSVKVEIVPFTHPSFAQKSLIAKIIPTQPINAGRTIVGAHQDSINGQNALNGRAPGADDDGSGTGSIFEAFRLLVVNNYVPKKTLEFHFYAAEEAGLLGSQAIAVKYKSDNVIVDGMLQVDMTGYVKPGTTEVIGIETSRYADTSISTFLKTLSAEYAAIPGVSTSCGYACSDHASWTKNGYKAAFLFESLFENHNKQIHTANDSLEKVSFSHMAEFTKLILGWAVEMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U366</accession>
    <name>A0AAD5U366_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000167">
        <property type="protein sequence ID" value="KAJ3222622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U366"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="111" mass="12532" checksum="68774205BE08CC90" modified="2024-05-29" version="1">MAGFEQKNPYVATVDLSERYGGLEKKEVKISNLSTEQLVLLKRDGKLNSETISMLESDGKLPLEDGSFIKKKKIEVNSGGINKNSVDIDEWIRDSPGLKKRDKKNKKNEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3B4</accession>
    <name>A0AAD5U3B4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1279 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000229">
        <property type="protein sequence ID" value="KAJ3221451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3B4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="17519" checksum="D14199D9D22F8D10" modified="2024-05-29" version="1">MNFRLTRSLLKTTDLNVKNKSIAMYSNKASLEAAAETLHQQQIKVQNQKESEKKTKRSLKELVLKYGATAVAVYIVLSSIAFVALLVVVKMQQLTPVEIENFVVKMLSYLPSFGNEGEQEEEKKGSYILHFFEGYNISESQAQKITDVAVAVVLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3E4</accession>
    <name>A0AAD5U3E4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Cu(+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ACA10_2</name>
        <name evidence="17" type="ORF">HK099_001944</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.8" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000160">
        <property type="protein sequence ID" value="KAJ3222776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3E4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140581">
        <property type="term" value="F:P-type monovalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000029">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000144">
        <property type="entry name" value="copper-transporting ATPase 1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-0187">Copper transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="24"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3222776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="707" mass="76990" checksum="FE718F6F6FF92E74" modified="2024-05-29" version="1">MSFGIDLNQLKEFLEPKNPKKLSEFGGVTKVCEALKSNLETGLSFNNADTNHTVVQTSTIVQDLEDKSLDEFKKVHPDDKNASFKERIDFYGTNTLPEPKSKSFLVFVWESLGDKTLIVLVIAAIVEIAIGIYKIIKTKETAGLFDGFAIVVAVLVVVIVTAGNDYRKQSQFRKLNDFSKGLASTKVIRNGQTTQIKNTELLIGDVAIIDTGDVIAADGIFIKGTDLKVDESSLTGESNAMLKDETKDPFLLSGTKVISGVGKMLIVGTGVNSVNGRILMTLNVETEETPLQKKLDGKEFPTDMYLKCCSIFISAVTLIVVAIPEGLPLAVTIALAHATLRMLKDNNLVRHLSACETMGNATTICSDKTGTLTMNQMTVVKGRIFNSEFDNQKRDVFQSSLLSTIPEDDKKQLLTLFGNCINVNSSADETENGEGKINFIGSKTDIALLNLTKLLGFSYKDDRKNANILEILPFSSEKKKMTTTVQYGAGDVCGTLKIPAKEQSEVLIFSKGASEIILSNCNKFVDEQGTLQDLTNAHKEKFVALIENYAKQALRTIAIGFKPLVNYDAKEEKGGEGQIVPEVSYSDPIGEEVPKAEVAKRDLSGEGLILLGIVGIEDPVRDAVPLAVKQCQNAGVVVRMVTGDNKVTARSIAQQCGILTEGGLVMEGPEFRNLSREEMDVVVLRLQVLARSSPLDKQILVNALKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3N3</accession>
    <name>A0AAD5U3N3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alpha 1,4-glycosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004049</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000278">
        <property type="protein sequence ID" value="KAJ3220723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3N3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006688">
        <property type="term" value="P:glycosphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007652">
        <property type="entry name" value="A1-4-GlycosylTfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051981">
        <property type="entry name" value="Glycosyltransf_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042:SF21">
        <property type="entry name" value="ALPHA1,4-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042">
        <property type="entry name" value="LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04572">
        <property type="entry name" value="Gb3_synth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="9">
        <location>
            <begin position="376"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="9">
        <location>
            <begin position="479"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="35"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="569" mass="67191" checksum="926C45BA78B11DBE" modified="2024-05-29" version="1">MSFLINKLKFANQINKTFEVENNKSLHDFTGDSEISEENSQFEEYKLQLVNAIKEKKMEDLGINLKNYRETPFNEDKLGVTIKVNEKFNIFAKSNREKISQNPQSDNFKFWDSPTYRVRQEEEKRLKVEMERTELEEKKKTEYEKEVEKKKLQSANDKKSPEQKSLDGEETCKNFYSQSRKTPFNIINGDGENFNFAGMTVRSLVNANYEVSEKTEELLSKDLSNQTNVPKTINFLNYNPTFDNLPYLCALESAARHNKDHYIKFYVRDKEDFYTVAEDWLNKINFKFRFIVLPLNFAEKFSNTPFESWYEEKKYMDSEWQMQNLGNAFRLALIWKNGGVYLDTDIISINSFKDLKHSRLVAREDSSRINNAVLSFPPKDPYIWSAMELFVNNWNGHTWGNNGPLCLTRAMIRDCNWNSLASAKMELFEIYRPNVTVADIESKKLAVPNNEPTKKGTPEREEQLANNRKYLEKYGNHTERPYCSSITVASRIRFYPIHYSQSNFFLKDWWKNCNFFKYIYEKSIGVHWWNRMFKFKNTKTNLSPNSTIAKIFNDQCPVYMQVYGLQSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U435</accession>
    <name>A0AAD5U435_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000186">
        <property type="protein sequence ID" value="KAJ3222209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U435"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08161">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="89"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1260" mass="147125" checksum="55D9C59763EBCEFD" modified="2024-05-29" version="1">MEDKYPRPHLSILAKEARNQVIKSWLQKKDFFGFKNDLPQNVVLTLEASFGLFPVEKWDNVVKCLVRHQYGTDNLESLKKKGFNQFNTNPFPITKSAVVEAVDKDDPREVGLRGGKKVLATRFLRNNEIIGIYEGFEVMEYEHAKDINILSEFYLEYKSISARPEIDVYKIPIDVFRSSGVRIPERKGNKNISIVNENDFVNFYCELVVDGSSNSGYFSWCSEINDFRLNPLEALNQPPLKKQLQNVRRPNVVFREVKILGWPVIFIVTTRTIQVGEELLIDYGLDDYWESMQRILKDHAIAKSIPQSIHPNFSAMALKLQELAKNFNFRQNEETNEKIKTIDLSDFYNDVDRLNLFLEKHFEINDSLENVHRSHYNSITGANNKQEEELFEDDDDFSVILDQYNNVNHCLSILVECIFYQLIRINYTEEFWRHFLGYDNYDITQDKFCKISPYWSNRITMYTSKNNPLAALFFKLESGHFTIEKVPAEISNSLESKHSRKELLVKAYLNIVDAINHPILLQNALSFSKEIVNSVPETILKSFNEYFFKCFGFCQTCSEVIFIPNTKILEHDLSLEQFFDDVCRCFNCKQKLPRNLTENNFNELNLLCKRYKLRPTLSNTKFTTKKTISAGSEKKVIEAPNMKKSNSINKIMVENIKKKNNANLNTITNEENVPHKIPEEEILINNIFETIVNDDFDKTSCRPIHLTNDEVNDFYQKILEPRFHTFNDFLEQAIISVKNSMLRNRSDILKKLNRIRIFKDLQLKALSEEVKMFYCRASDIEEMQNNLQANKRIPQLEGISSMQNSEKPPFNSSLRNIATPLLKKNEENQLESFTELTQDRKTTLEYSAVDDVRTDDRKDFFENQIETYKIMFFEELLPKHKDIYFAIKILSNFPHDPIALEKKRKLNTMLKFINTQLNSFNEGDSRTDYYMTLKNLCRMVCIPSESLFRLYFKIDNAKKDIDYVSNFYDNRNIDFANVISYCDGKKIKYTGGGSLEEKSAIKDTSCQNRRWKSMEKGVKVNITVSNKSKHPNKFFGTTVNPNKEKIKTIEPKNELLALLESILLRCCRLESEYLYIENGNKYTFKDSLSKKKKVCQAFSDITLKFDKEYPEDELCILFDFPLCLDPLNENLHHNEEQYSFGDLSRTVKRVKNPQLQSKEPFKADADFPKNYNGTEYSTIQDNKCGGNDVIDLTCSDIEVGKNHPKKILAGKLVMEVENSLLTSSSRKEIKYFKTSKRKFGQHSNLYIDPDLHPLFKRYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4D2</accession>
    <name>A0AAD5U4D2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thioredoxin reductase</fullName>
            <ecNumber evidence="8">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TRR1_2</name>
        <name evidence="11" type="ORF">HK099_002499</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000183">
        <property type="protein sequence ID" value="KAJ3222267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4D2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000064">
        <property type="entry name" value="Thioredoxin reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050097">
        <property type="entry name" value="Ferredoxin-NADP_redctase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48105">
        <property type="entry name" value="THIOREDOXIN REDUCTASE 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0274">FAD</keyword>
    <keyword evidence="2 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="10">
        <location>
            <begin position="38"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3222267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="363" mass="39532" checksum="8E153A5C55E42BBF" modified="2024-05-29" version="1">MFNLFCKLSKPQKIKSAVAFCAIFPLSKAWHSTKPLPNVVIIGSGPAAHTAAIYASRANLNPVMYEGFMAGGVAAGGQLTTTTDVENFPGFPNGISGMKMMELFREQSLRFGTKIYTETVSKVDLSSRPFKLWLENQEGEEPIYSKTLIIATGATAKRLIIKGEDKYWQFGISACAVCDGAVPIFRNKPLAVVGGGDSACEEATFLTKYASKVYLLVRRDQLRASKIMQERLMKNPKIEILWNTIPIEAKGNADSQLLNQIVLKDTKSGENRNLQVNGLFYAIGHEPNTKIFKTGGGKDGLEPQLKLDKDGYILVQPGSSVTNVEGVFAVGDVQDKRYRQAITAAGSGCMGALDAERFLAENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Z9</accession>
    <name>A0AAD5U4Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000083">
        <property type="protein sequence ID" value="KAJ3224727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4Z9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="40849" checksum="4B1DBEBF1667DD33" modified="2024-05-29" version="1">MTPEEIALENSFLHNRDSQYLVLTIIDSVILALTLYNFFLAVKILRTRTSQPASNYLFLAHTICWIALCVASLLGDIGFLVSKPLRKDPFWRDVVWGFMWNTPNIVGITLYEILTVDRFITIARELYFRKRGKLIKIILIAAVLLLNLPCLIIATMQFQCWYLQDMEVEVVYDFCYQDWLMELYNLTWSIQKINLTVTETVLGLALIFVVGKNINNVKLKDKYYVDEKTKKKVSMKFALKKLIAFIVLWILIVLAAGLLGGLILYNGEPGWFLFSTDKVTNISIYNILLEISVFLVTLEFSLFFVFTNQLLVVLNMSQASLSTNLESSLVSSMNKDVTQQSDSEASQFVSTAESEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5A2</accession>
    <name>A0AAD5U5A2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000077">
        <property type="protein sequence ID" value="KAJ3224901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5A2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="239" mass="27277" checksum="63645D577F080686" modified="2024-05-29" version="1" fragment="single">MWEDCGKVFATEKETYEHVFSTHKGVGQQICKWINSKTRGACSTVLKHKGQLKDHVISHFSCNLKPFECSLCKKPLRNRQQLNTHKKLLCKRKNIPNVSAAGSNNNLISLTNETVVNENYGPPLLLKSNFSPNDSLINANNFSTENYSNFFFNSSLVNNLINFDNNVKHSDLMPSKNFEIELKKVYPVSFPVKELSQHNDSLKELCESFLNLQLDTEHSIIMNPYIKCAIGINVVFYWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5A6</accession>
    <name>A0AAD5U5A6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003116</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000209">
        <property type="protein sequence ID" value="KAJ3221783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5A6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="58733" checksum="DD3605DB5C8138AF" modified="2024-05-29" version="1">MISLHSQLNTLLATYQPKFIFFSVFLAVITLIISKFFIKRSLFHSSLNYPVATTKLPILGPAIQFGVDGLNFLKNQKEILGSNVFLVDLLILRFHFVLGAKNTQAFYKASNDDLDFLAGVPILLPELVEDAWDVDPTFQARGHALALKGFNQKEKLDFALELLIMEVDKAIDRWDKMDKVNMFEECTRLTILVTLRFILGDKVYNEKGEELANMYDQLEKDLAHPLVMTCRPLPTGPYRRLIHVRNTLLQVIRECVETNIKSQKDDGSFLSLLVKELGPEYWYQYGYLCLGIILATRTNTAGVLAWTLSHLCDDKKLMDKVLQELKSTDSFQEGMGEIGSGGKSYPIKEYTFLDACMKETVRSYSNFMQFRKVTKKGGFEIEPGKVIPEGELICISPAEEHHDEKIFENPFEYKPERWLDQEYWAKRSREMAYVQWGFLRHRCYGEKFAQQFDKVAWARILTKCVLTVENSDQKIPECLWGSGFGTSFPKDDKPYFIKIKKRREGFNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5E4</accession>
    <name>A0AAD5U5E4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic peptide chain release factor GTP-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ERF-3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">ERF2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Polypeptide release factor 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Translation release factor 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SUP35</name>
        <name evidence="16" type="ORF">HK099_001184</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000131">
        <property type="protein sequence ID" value="KAJ3223411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5E4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018444">
        <property type="term" value="C:translation release factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002184">
        <property type="term" value="P:cytoplasmic translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03704">
        <property type="entry name" value="eRF3_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04089">
        <property type="entry name" value="eRF3_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000017">
        <property type="entry name" value="Eukaryotic peptide chain release factor GTP-binding subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000503">
        <property type="entry name" value="Peptide chain release factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000020">
        <property type="entry name" value="Translation elongation factor EF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003285">
        <property type="entry name" value="Sup35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01343">
        <property type="entry name" value="YEASTERF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Tr-type G" evidence="15">
        <location>
            <begin position="151"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="23"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="103"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3223411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="581" mass="64459" checksum="72E2E9E7020DF593" modified="2024-05-29" version="1">MSSKKGLNPSASAFNPSAAAFVPSWIQQAPPPQQTSQQNVQYTPQQNVQEPKQNVQQQLNQPAQQSLQQSQQNNTFSKPAVSKSLNANSQTNNQQPVSSPHQSKSEKPAAVEKKVNEDKKPSEEKKTERKEKEFVETANLISDELAFANLKDHLNIIFIGHVDAGKSTMGGHILYLTGMVDKRTMEKYEKEAKECGRESWYLSWALDLNPEERNKGKTVEYGRGYFETKNRKYTILDAPGHKNFVPSMISGAAQADVGILVISARKGEFEAGFERGGQSREHAQLAKTAGVNRLIVVINKMDDPTVAWSKERYDECTGKLVPFLKSCGYNPKTDITLIPISGFTGANMKDKVDPKVCPWYSGPSLLDLLDSIDLKDRKFDGPLMMPIADKFKEMGTVVTGKIESGTVKRGQTVLIMPNKKMAEVLAIFSEDSEVQAARSGDNIRIRLKNVEEEDVLSGFVLCGPNKPVHTVTAFEAQIAIREHSSIICAGYGAVMHAHTMTEEVTLAALLHKVDRKTGKKTKKPIQFVKQGEVCIVRIETTQPVCLENYADYQQLGRFTLRDEGKTVAIGRITKLILSESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5V5</accession>
    <name>A0AAD5U5V5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cas12f1-like TNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000183">
        <property type="protein sequence ID" value="KAJ3222269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5V5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Cas12f1-like_TNB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="Cas12f1-like_TNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas12f1-like TNB" evidence="3">
        <location>
            <begin position="154"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="31"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="218" mass="25199" checksum="386F576C0501508D" modified="2024-05-29" version="1">MDFKPRIVAGVDLGDRWPVAACAVNYETKVKKQLKIRKRNLYSGLKELRKETEYRKMNTGISLVEAEVSDMKSRLQHMEQLMKFYSSKTNVSHVWKSKKVQQSTFDKLFRDMLALADIPNNRKITEFEINSVLFVFGDADFSTFRGLPSLHTTIQEFFIKKDRALSLNVVGCDENYTSQTCSTCLKQLSSIGLRIKHCRLWKYFHRDVAAAECMAHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U686</accession>
    <name>A0AAD5U686_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytosolic thiouridylase subunit Ctu1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CTU1</name>
        <name evidence="11" type="ORF">HK099_006068</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000050">
        <property type="protein sequence ID" value="KAJ3225865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U686"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002144">
        <property type="term" value="C:cytosolic tRNA wobble base thiouridylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="CTU1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000132">
        <property type="entry name" value="Cytoplasmic tRNA 2-thiolation protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056369">
        <property type="entry name" value="CTU1-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032442">
        <property type="entry name" value="CTU1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000541">
        <property type="entry name" value="Ncs6/Tuc1/Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00269">
        <property type="entry name" value="TIGR00269 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807">
        <property type="entry name" value="ATPASES OF THE PP SUPERFAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807:SF12">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16503">
        <property type="entry name" value="zn-ribbon_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="9">
        <location>
            <begin position="11"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Cytoplasmic tRNA 2-thiolation protein 1 C-terminal" evidence="10">
        <location>
            <begin position="257"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="299"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00060195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR004976-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3225865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="337" mass="38515" checksum="FD2D9B52F71D301D" modified="2024-05-29" version="1">MFLKLNEIGDKIAIAASGGKDSTVLAHIMKLLNERYLNRKIFFHWLLQRYDYGLDLFLLSIDEGISGYRDDSLETVKRNQLEYQLPLKILSYKDLYDWSMDDIVKEIGRKNNCTFCGVFRRQALDRGAVMLGVDQIVTGHNADDIAETVLMNILRGDIARLQRCTFIKTKSEETIPRSKPFKYTYEKEIVMYAYFKKLDYFSTECIYSPNAYRGHARVFLKDLEAIRPSTILDIIHSGEAFETSAESNPTNVTVPGVCNRCGYMSSRDLCKACLLLEGLNRGLPKLGIGNTEKLRKKHLDEKEKSIGEYSSSKRTPGNPFIQNFNDLKLGSDLKKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U687</accession>
    <name>A0AAD5U687_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Centromere protein X</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006406</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CENP-X/MHF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000055">
        <property type="protein sequence ID" value="KAJ3225685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U687"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071821">
        <property type="term" value="C:FANCM-MHF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22921">
        <property type="entry name" value="HFD_CENP-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018552">
        <property type="entry name" value="CENP-X"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28680">
        <property type="entry name" value="CENTROMERE PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28680:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09415">
        <property type="entry name" value="CENP-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9737" checksum="49A2A6AE8FD34B59" modified="2024-05-29" version="1">MDINFLKVETVYAILKTKFKDETLKVNKEAISISSLYMSIFITEAIIQSTKKSKLSNELVHKADIPVVDTEHLEKILPQLLLDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U695</accession>
    <name>A0AAD5U695_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cilia- and flagella-associated protein 157</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006337</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CFAP157 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U695"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038844">
        <property type="entry name" value="CFAP157"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31954">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31954:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="36"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="668" mass="75823" checksum="A0407EB43A0DE88A" modified="2024-05-29" version="1">MAKKGGKKKSAGANSAEKDDDALKNGEQQALNEITIQVYEAKIRDLNEKLDRYKYKCETLVAENLNLGSSQAKFSQDRQDIVEFLNIKVQDHEKLINTLEAQIRALEAEKKDMEAAGKQKLNIANEEYKAEVELLHIQCAKYKADLDQLSEFRGRKEDMEFQIRYMRQQLDLKEKEYKEVIHSMERKVLQDKNLMKKEMLQKVNEAVANFRRVADQQMAETTKRAIRENMAITAQLKKMSAKTMELIAENESLMVRVAKLKSKNSLLVDSEKDLARKNQANQRVIKMLVEKLKESDKMLEVAYDTGAFNLEENKTFLDEFPAPQNFNFTSSTAPSYPSSTQQQLKLSMVKEDTAIHQTQLSQQSLQLSTNEQIQDLKIKLESLKFANNLISNKAIDYQDKEGNTLEDNAVKNLSLKKFEEEEILNFIKEFLTTGIGGEGNSIVSMSSLKNMIDRIKSTIKIDVKCPDGLERKGRESLGPILQTNSAQKKLILTSTSPALGKRASPNLKTLLNHIPSTLKVLQYNEKLKENGEESCLNEECSNVLTIQNNISVEENDAVIHRTNLFSRNGIKMKSIAVQTRNLQFGPKMVKTDQLLSELRPWGPTAHCMPKKGTGLYCPRNHRESSNSSQYYNPQTVHSKHCQSSSELSLFEPTPSTTILFESNSSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6M1</accession>
    <name>A0AAD5U6M1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type I HSP40 co-chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YDJ1</name>
        <name evidence="9" type="ORF">HK099_005489</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6M1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000068">
        <property type="entry name" value="Chaperone protein dnaJ 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000041">
        <property type="entry name" value="Chaperone protein DNAj, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="127"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="372"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="408" mass="45086" checksum="2BB5246A02EB4E45" modified="2024-05-29" version="1">MVRDTKFYELLEVDPGADEATLKKAYRKQALRFHPDKNPEDPNKFKDISHAYEILSDPQKREAYDRFGEEGLQGGGGLHNPMNPEDLFAQFFGGGGGFGGRQRPQGPRKGKDMSHSLKVTLEDLYKGKVSKLALQKQVLCSKCDGKGGKDGAAPKKCTGCQGRGIKIVTRQIGPMIQQMQQQCPDCRGEGEIIKDKDRCKGCSGKKVVTERKILEVFIDKGMFHGQKITFTGEGDQAPDIIPGDIIIQVEQKEHARFERKGDDLYHKVEIDLLTSLAGGKFTIEHLDGRILLVNILPGEVIKPGDVKSINGEGMPRPFDKGNLYVTFSIKFPEPNWVPASLLPTLEQVLPPRKPLDNVTGNTEVEECILSTVDPIEQQRNARGGNRGQAHDEDDDEDGGQPGVQCAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U725</accession>
    <name>A0AAD5U725_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein mrp2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MRP2</name>
        <name evidence="4" type="ORF">HK099_004174</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U725"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="100" mass="11613" checksum="3C32B3458945F910" modified="2024-05-29" version="1">MPLNIGIRDRIARILTSKHEVDREAWRLIVKNKELPLKVRLQAQDFLNSYPRYMRPSAIKNRCIENGKAQGVLDDFKLSRVIFRQEALAGLIPGVKKSIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Y9</accession>
    <name>A0AAD5U7Y9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TTC14</name>
        <name evidence="3" type="ORF">HK099_000067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Y9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039190">
        <property type="entry name" value="TTC14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23184">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23184:SF9">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="226" mass="25666" checksum="FE1FD9D65B24B68A" modified="2024-05-29" version="1">MEKSSISEKFIKFYNLNNVKEKINNLEAVCDLKTAADTSNELHNCLKEINPDSSVLFEEIYNIKSLSTFCNGSPLKHYLDVKEGINLLREGQIEKAIKKYTNAIEISPICADAFVARGAALANLEDYKKAITDFKIALKMNPDHPNAKKYLETTKEKKKLKKQEKKALMKGDYVMEIDAPTTALNLIVSEENNSKNKFKSNSLSTEVEGNEKNRKYVKRLRSDDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8V3</accession>
    <name>A0AAD5U8V3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein tyrosine phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000080">
        <property type="protein sequence ID" value="KAJ3224821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8V3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00047">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF449">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="3">
        <location>
            <begin position="209"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="34907" checksum="800C387D3D05819D" modified="2024-05-29" version="1">MDLLHQNTLKTLKSDNIYLSQLFSTIPNNRFEFKNCDTACNPVNYLLKNRYSDILAQDTTRVKIQYSHPNFSVSDYINANYIQFDGLDVQYIATQAPLETSTFDFYQMLWEQNSNVIVTLSSAIDQFKAKAYPYWNYGESQERELTIYTLDENGVQLSANSDFFVTLLKVESDGKIITREIKLRKNAEERVVTQIHYSGWPDFGVPELEDFQLIFASLQRLYISGPVVCHCSAGVGRTGVFIAVDAILKLLKKKKNTLFHADEKSDLVYETVCKMRKQRIGMVQTPNQFLAIYLAVEKNLEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA40</accession>
    <name>A0AAD5UA40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000051">
        <property type="protein sequence ID" value="KAJ3225830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA40"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="283" mass="31873" checksum="12F8EBC97A60CFFB" modified="2024-05-29" version="1">MTLTQAHPHIQHPPWKLNFQRALHANSSKLTSIILTAVNSSTGKPISKNLKFSGFHSGLHTKANPLAPGSPNTVGKIKLEGLMQFAIDTRGVLSLLLSFFHSILYLGVKDWFGIPKHNDNDKFIDVSCFFGETQRLFRFSGKVFLIVEQGSFDPPHSIPPWSPKDIDWEEERKYLWKLSTQKNQFCSSIDLSYDAESYFSVGGVSNAPTEKNCVSYQSTTNNVVVDENTVPSNFGLLLVDVDYVDEINLEEPTLKTIYQVKVPLRTYGRVSGCEWEEKKEVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAI3</accession>
    <name>A0AAD5UAI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_004973</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000037">
        <property type="protein sequence ID" value="KAJ3226395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAI3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47235">
        <property type="entry name" value="BLR6548 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47235:SF1">
        <property type="entry name" value="BLR6548 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="803"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="840"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="871"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="915"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="969"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1002"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1026"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="8">
        <location>
            <begin position="804"/>
            <end position="1052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1187" mass="133285" checksum="81C9CAFD42B20952" modified="2024-05-29" version="1">MQRLYSTCYYRWGLSSNIGISLRDGLEVAFSHFNSEEASDLGFNISLKTLDDGYEINKAENNLIEFIENYKVFGLIGTMGTPIVASELNFTRRYEKVNRSYIPVIGHFSGGMSLRAREGEPFPYQIINIRGSYFDEASAMIYFLLEHLSEIRRVSVFYQRDAYGQTGLDGITKSLKEKSLTVHSSGHYERNTADVTEGINQIFKGRPQAICMFGTYQAVAPFVIAAKKIDPNIVFMAVTFTSPAAVLKEMIKLGGSESSRNFYVTQGLPLYTTNSSELIQELNRDYTAYNKINTNVTAVDALLLEGYVTGRFAIEIFREMKLNGISPQDFTNESFLKTVYSTSIFDIGDLRIGPFGDTSCDLIGAGCRCNQGARKIWISAINETTEEYYEVPSTNFQFATCGVRFQLPKEILFAISANLETSQGMAFVNGLKVAFNAMNEKGVMNGITVSLLINDDKDNATVANDFAKTLKDKKVVALLLPMWNSSFSEARKTLSENFIPVVNDLRAYTNSPSVIQLIPSFNDIIQDLYLFAFNHLQLRKFSAVFSGEYQELQSQLISRLLEGFDQSVSSIFTMDNSDQILPSLSGAIFIVGNLSFTVSTINVLEKICSDCVYLISGLINAAELKGKIAVTAERKSFSTSNLPSVINSSSLVVKEFYEDLESLISIEISQVNKGKFCTLFNIEKDVFIGYITGLFVVEVMRRSKNMSDPVQFINSIYSTRVFQFHEVTFTGFLADENFDKVTGFHSLSYEMTGMDKLGFCNYGFEKNGITQVSDLQKHHFVEVLKNPNQCTNSLRTFHKKSTAVSVIMLTLCVAGIALTLLGVAYVYWKRNENIIKASEVVMVISVLLGIIMMYCIVIVKVGYPKLDSCMAIQWMDNVSFVLVFGSMGAKSYRVAIVLRDTKKIDIRNTFVKNKFFLYITVYGLCTLISTYILVWGIVSPKVLVLEDFRDQNVHECFQKGSSIWQLVPVIFQLLLLILGIFLTIQTRAAWAQFSEYKMNGIAMYNFSLSMLIIYLVEYAVYDLDLALAVTSAIIVYNATVKIFLTLGNKFRISEEELQKIKMSFGKTSSFGKGTSHQKDKKCRDATSSFTPSEIQKSEFQESQFLDISQKQLPKVEGGLRDGNDNAHLAKEYLKSSDAVRKKEGDKNLKEGIFGIPQDEQKCRSYRDIYSRRSFCAPTPQGELGGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBY2</accession>
    <name>A0AAD5UBY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rab GDP dissociation inhibitor alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GDI1_2</name>
        <name evidence="5" type="ORF">HK099_006050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBY2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000001">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000232">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2 3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="565"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="3">
        <location>
            <begin position="596"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="598"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3228170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="930" mass="104120" checksum="BC2E5691A175B653" modified="2024-05-29" version="1">MDETYDVIVLGTGLTECILSGLLSVDGKKVLHMDKNDYYGGDSASLNLTQLYKKFRPGQEPAAAYGRDRDYNVDLIPKFAMASGEFVNILYHTDVTRYLEFKQIAGSFVYRDGYVAKVPANDKEAVVSSLMGIFEKRRAKKFFEFIQNYSFTNPSTQCGMDLNTVPMADVYKYFGLEAGTKDFIGHALALETNDDYMTQPAKATYEKICLYMNSLARYGKSPYIYPMYGLGELPQGFARLSAIYGGTYMLNKKIDEIVYENGKVVGVKSEGEIAKTKVVICDPSYVPDKVNKVGQVVRVICLLNHPIPDTGNSDSVQLIVPQNQVKRKNDIYIACVSTAHQVCAKDFYIAIVSTLVETSTPEKECDAGLALLGPILEKFVDISDIYEPKTDGKEEGVFVSKSYDASSHFESVCADVKSIYKRVTGNELKIEGKVKKIDEDGAVTETAAERLDKFDKKVVAWKNDPVSPYYEYQLIQDRLDQLKKAREAKDLSSTLFLLRTSLTRNLGNMTSEKLHGVSKVGTKKLIEVCSQLQIICETDHADNLNPDEKYEFFMNTQKSFGRTALLLSGGAVFGLSHIGVVKALLETKLLPRIISGASVGSIIAAVVCTKTDEELAYILHYPNNINLDVFERPDEQNGWLLMFYRILHNHVVFEIEVLIDSIRANVGDLTFQEAYYRTRRILNITVSSSTLYEMPRILNYLTAPNVLIYSAVAASCAIPGVYKSYPLMHKDRNGKSGVWNQSGTKWIDGSVESDLPMARITELFGVNHFIVSQVNPHVLPVMKAFSLPLVKTTSYLLWSEVSHWIQQAIELGLPGNVLQRAQSMVRQRYTGDITIIPSIPLSNLTEIMGNPNPELILYYSLLGEAATYKLIGRIKTHCQIELVVDEMLYRLRIRKLSSDEDHLNGPAFGVRSRFKQGMGFTHHTKGSSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRU9</accession>
    <name>A0AAD5XRU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Hexosyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_002863</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010001996">
        <property type="protein sequence ID" value="KAJ3199984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRU9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051072">
        <property type="term" value="P:4,6-pyruvylated galactose residue biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF351">
        <property type="entry name" value="BETA-1,3-GALACTOSYLTRANSFERASE PVG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3199984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="284" mass="33358" checksum="E778AD033DA1E43A" modified="2024-05-29" version="1">MLQKLLNDNQTSLKTRLNLTVTLIVTIFIFSIFQIISLSNAEKTVNFDIKKEKITLFGIFSTPSKFHRRNLIRSTYLQLVDDTNIDYKFVVGRPNNREELELLQFENKKFNDLMILDIEENMNDGKTFHYFQTVYYKFKQNKYKFVMKVDDDTFLHLPNFEKKFSTLPTTGLYFGRYWGSVKHRNGFMTGMGYALSWDLVEHIAEEVPLAGKSIIGQEDGLVPSWIGEKAVNTISEDLEYYDSPKSNEDWAKNYTDGTLLIHRLKRDDWFLNASTHFLKDYLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSN8</accession>
    <name>A0AAD5XSN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Electron transfer flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CIR1</name>
        <name evidence="9" type="ORF">HK099_000542</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001126">
        <property type="protein sequence ID" value="KAJ3206424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSN8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="245"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="524"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="769"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="441"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="530"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="774"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3206424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="798" mass="91157" checksum="AAE1D299BF359162" modified="2024-05-29" version="1">MASKLSSYGANIALADDYNFPIRGPTNKTREETLSCRFCSAPLNKLKSCDNCVKGLKGEFALSMNNCGMQALEKSLNNSFKFKALEKMDFKSTSLTEESLKVESLCSKNIEKIYKKDSESNQNPIRREYFNNLNENSNSKNKFELPPVSQLLKNLQSIDIKQVEEKNSTPTPPQQAATDVVAAASDESEAIKNTEMNSYTENGGSYKNKPIIHVGNSQILLHQRNVSSQAATPAAVTLSQSSFNYGSNLMCHNCETVVTPLWRMDDTGKTICNACGLYLKMNKVHRPVNKKIQATRIAKTVQQANAAKTTEDASKGWSDCGQGNSSVYSPFKDKKVVNESDSTTSFKRRKSNSPENSLQKVKISKNLNSENSGTRSEILKLKLQQKSEQSTLNTNPKTGNSNHHNQKYLQQQINSNSTGQEMDLINTQDHYVQNSSKVHQHQIQQSHSQQQQNANVGSYYIKNQQPQSNIQQQQQQQPQQIQQKLSNLKNLHNEIAAPSHVKLGESMMQIRELNRSFNTPFLHNQERKPVSSQHYSDTQTQQRSHYNHERFTPASAAPVNTEYQQQQDYSPYHHPSFNQRHLYQQTEAHHQKLIRTSSPMLMSRPNEPKSYSQSNFSNQIPTHGMISQPNRSLQQQSARSRLIPANQQISVEENNRREYFAQQHIARPSSRPNQLQLIPEVYHYNESIYHDQAMQEHALNSQMHPYSYRNKADLSSQMRMKAESHNRLESNSQSFYQHQNPHHHQYEISPTPFVQQKFISNALGNVPSYKDGQMSRTNYPNHYSQNPQQISYTHPQHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSR1</accession>
    <name>A0AAD5XSR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000672</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001168">
        <property type="protein sequence ID" value="KAJ3205896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSR1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF7">
        <property type="entry name" value="FUNGAL TRANSCRIPTIONAL REGULATORY PROTEIN, N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3205896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="165" mass="19006" checksum="761652ED066D5183" modified="2024-05-29" version="1">MNQGKYSNKKATASSHVSKSCTNCKKAHLKCDNQRPCFRCTKTGNCETCVDTVHKRRGRPHKKPYTKNITINEQDFSSTSSESSSADERNFRKKEKELIPKSPPLTPITENIPSLRRFQFAGQSLETIGRSLQFEKLTLPPLRNNLAFEEIKIKKIEKPWYSNWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT48</accession>
    <name>A0AAD5XT48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000936">
        <property type="protein sequence ID" value="KAJ3209517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT48"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001153">
        <property type="entry name" value="Barwin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00967">
        <property type="entry name" value="Barwin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="242"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3209517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="461" mass="50384" checksum="EC603793040297F6" modified="2024-05-29" version="1">MDRQKINDSDCCCLQGTKPTSGLNCEKPFQLKSVEKEKQEKTKKNPKTTSIKSTMTTSIKSTKTTSVKSTKTSSSLSSAISTPSSSDGFKTAYATFHSYQLNQGVTSLACSDKFTPKGIWSLSNLKVTAFNVGTNPETGRVNCGKCLEVKSATTSNREYITIIDGDGKIPGYDFHLDLSPDSFNYLLGEKGVQNGHGLVDFRFVDESYCTPFKSSTTVSSTTSASGSTATQTPPISDASCMKSYIVKSGDIGVSIAAANQITFDELSRINPNLVWTNLKIGQILCVKKTLNTSNTIENTNSDGKKVLHSNFDVNKNITGFGTYYYDYLNNVCPNEAYDTYPENKGITTCETYDSTSPMYKTTLGSRKSNYIVAISDIILNKDRAKYCGKKVNIKYNGRLVETEKPFFVWDGCGACTNVKQPRIDLSLSALQNIAGEKACADGVVEGFTWEVVDEVVFPFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTB6</accession>
    <name>A0AAD5XTB6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">26S proteasome non-ATPase regulatory subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PSMD6</name>
        <name evidence="6" type="ORF">HK099_008095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the 19S cap proteasome complex which acts as a regulatory subunit of the 26S proteasome, involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively. Component of the lid subcomplex of the 19S RC.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000855">
        <property type="protein sequence ID" value="KAJ3211107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTB6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005838">
        <property type="term" value="C:proteasome regulatory particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000005">
        <property type="entry name" value="26S proteasome regulatory subunit N7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000087">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049549">
        <property type="entry name" value="RPN7_PSMD6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21154">
        <property type="entry name" value="RPN7_PSMD6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="509"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="383"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00093435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00093502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3211107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="705" mass="80475" checksum="5F3B99B39C2582C0" modified="2024-05-29" version="1">MLEIDIESINGSFSPQLTSASLSQSSCFVSDQEDHSDTFSSQQHNNVQNSEFINHNENEIKHNGCQLVKKKRKCSNPLRSIDSQLTLEDKKKLKVFKLDVFTLKQKKYKNIFINNSCSLYSRKYSDLTNQKILFENNFINSQKASNLTFTANANSTYNDRTVKRPTKGKPFTLRNQGVASGRENFNPKTNLKGSPPLFTPKTPSIEKTLPEYLTKDPTLVNIVDMNIFKDTESAPALAWKGHPLLIETDSERFDELTPEELETCVTVRLLPAHYLYIKEILLRAAIKGPPFKKRDAQSWFRIDVNKINKLYDWFVSIGWIPSCPETWDSHIKSLLQRGKFLVLNGNAAQKKTALQKLNESIKADHMTPFYKLLCQQLNLTPDKEQIKSLQEKNDEALAKLEERLVDAETNLGETDISDALIAKAEYLAKIGDKEKAEAAYRVAYEKTGPLGHRIDIVFSLVRIGFFFKDHDLINRNISKAKSLIEEGGDWDRRNRLKSYEGIYKIGNRDFKGGVNLLLDTLATFTSVELMEYKNFVKYAILSGALTLKRPDFKAKVIDAPEILEVIHEIPEYAEFANSLYVCNYSQFFKSLAIIEQHLKYDCYLSPHYQYFVREMRIIAYAQLLESYRSLTIESMANSFGVSEAFIDGDLSKFIAAGRLNAVIDKVGGIVETNRPDSKNAQYQNAIKQGDFLLNRIQKLSRVINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTQ4</accession>
    <name>A0AAD5XTQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000723">
        <property type="protein sequence ID" value="KAJ3213312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTQ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="96" mass="10898" checksum="43E6FFBFB70558D9" modified="2024-05-29" version="1" fragment="single">MSSWFYTPYTLPKTYVKWISKMADMDESLLQVLRLIKGKELIYGKNTGHEGVLLRYTKEIGLDPSFADPALGQISCLVVHGGIKGCEKFALYTFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTR7</accession>
    <name>A0AAD5XTR7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Guanine nucleotide-binding protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GPA1_10</name>
        <name evidence="8" type="ORF">HK099_007270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000693">
        <property type="protein sequence ID" value="KAJ3213621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTR7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000001">
        <property type="entry name" value="Guanine nucleotide-binding protein G(I) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002307">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="175"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="200"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="269"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3213621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="353" mass="40744" checksum="9B2BEEF9DD5DEB67" modified="2024-05-29" version="1">MGCCMSSEDQENNKRNQEIEAQLKREKLIAEKQVKMLLLGAGESGKSTILKQMKLIHDSGYSTEEKEAFKEIIFSNTVQSMRVILEAMQTMNIKLSSKSHERYFQTILDLPSQIEAEVFPQEVSIAIKSLWHDAGVQHCFSRAREYQLNDSASYYFESIDRISQPNYLPTDQDVLRSRVKTTGITETTFHIGELTYKLFDVGGQRSERKKWIHCFENVTAIVFLVAISEYDQVLVEDETVNRMQESLTLFDSICNSRWFVKTSMILFLNKIDLFKIKLNKSPMNKYFSDYKCPNDFESASQYILERFVSLNQSAQKQVYTHFTCATDTSQIKFVMAAVNDIVIQANLRDCGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUL4</accession>
    <name>A0AAD5XUL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SLC41A/MgtE integral membrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005908</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000483">
        <property type="protein sequence ID" value="KAJ3216339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="entry name" value="SLC41 divalent cation transporters, integral membrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045349">
        <property type="entry name" value="SLC41A1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228">
        <property type="entry name" value="DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228:SF7">
        <property type="entry name" value="SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="MgtE membrane domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="10">
        <location>
            <begin position="98"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="10">
        <location>
            <begin position="455"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3216339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="591" mass="66147" checksum="8D389DDEB9CFC58B" modified="2024-05-29" version="1">MELFKSIYSTNVEYKKIENVELGTFNLKDDNIELKKNEISSEKITDILFKFFIKNQILIEVLPSILLSLGGLIMAGELLSLIESWKIFEKINELFILVPILLGLKGNLEMTLAARLATLANLGYLDRHASPLSETVTKTKNTYCFGYFSEDQWKILFGNFAVLQIQSIIVGLFAGSWGWVLGGCRHGVGHLAIIVSSAIFCFVVSSMFLSILMYWMVMTCRKFKCDPDNVAIPVAASFGDFAVILMLAVCGKMFEAFEKYNDLISYFLIGLNLIGLILWIKPVRGNSYVKKVLSEGCISMILSVLLSSVAGVILARSIVEFQTMALLVPVLNGLTGNIASIYASRFSTSLHLKENSKVDKVLTKFDEDSGHLDISCPPLNFDQNVPLQCVKVTKETNCRTNSDNMYTCIDSNFEALQLSTNFIDDSHLKVENLCELNNIEINTNIYKNATSGDKTLKKNNKHAFFSLLALSTLIGSAFLIFVKIFGLANVKMDLMFFLVYSLVNLCLTIILLYVAHHFTSFIWSKGLDPDNISLPYITAVADVLGTVLIVAALSLMKYHIGPYLKNSHNINKMPYKKKPTETIKLISRKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWT5</accession>
    <name>A0AAD5XWT5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002361</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000178">
        <property type="protein sequence ID" value="KAJ3222373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWT5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="9"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="443" mass="49724" checksum="5EE7B62A5CE48DC6" modified="2024-05-29" version="1">MNLEVEPNIVISGAGIAGLVLALSLRKMGVAVTVYEQAPSFDDGVGGAIGLYPNGLRVIRDISIEVLREIRKQGRSYIYRRWMRHDGSEVAVGQEKYLCEFKDEQEEEELTSLGIRRWRLQKILVTASERMGVKIIWGKRINLVKVIDPENDIKVELTLSDNSKVNCDLLFGCDGVKSAIRTSLFGNEADPSYTGITCLMGSAPIAKKSPLNGICFPSSVTSKCHACFYPCNEEEIIFQIYFPTEEKPETWKPLTLEESKIECNELAKTLKNEGWSSIFTDCLLSADSVLRVGLRARSPIPVWHSPKNNPRVILLGDAAHPPVPYIGQGAMMAIEDAGILSLLIKSFCKPNEIAKFNLNNLPIVSKHYEGLRLPRTTTMLEKSHELGKMQLERATNTNKFEIWYKEMTMWANVKRFGTLPIMLNGASYNYQSAVEEELRKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX62</accession>
    <name>A0AAD5XX62_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001562</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000145">
        <property type="protein sequence ID" value="KAJ3223081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX62"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36459:SF1">
        <property type="entry name" value="FATTY ACID DESATURASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36459">
        <property type="entry name" value="ORF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="3">
        <location>
            <begin position="86"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="420" mass="49570" checksum="1A4353406859B7BD" modified="2024-05-29" version="1">MVIQLKDTEIIKSLFDKEYLENKKVNNSIQNNPHEKKNITTQTSTFDKIVEPLIQDKRDVVFVKLSLKLLLLVSSSIYMIFYKFSWIHFFIHAVFQAKFTVSYILMLHCCCHKNLYKPKYWYLELIIPYVLGPFLGQTLDSFYFHHVKHHHVEDNGPGDLSSTLKYQRDNWFHFVCYFSRFLFLSWIELPLYFAKKGWYLTGLRVMMGEFITLGFFVACTKYANTNGALCLLWFPFALVRFGMMSGNWGQHAFIEPTRMDDDYVQSITCINSEYNNVAFNDGYHTSHHLNPIRHWADHPGNLVEQKQKYHDKGTIIFNNLDFHLVWVALMLKDYKTLSKSYVNLNSAGLEIEKSEEDLIKIENLLRRRTKRFTQQEIIKYYGKPTSKPIYEVEKDSKPKSDQGSKKESGQYKPKHEKSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXC9</accession>
    <name>A0AAD5XXC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hsp70 nucleotide exchange factor fes1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FES1_2</name>
        <name evidence="4" type="ORF">HK099_000651</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FES1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000116">
        <property type="protein sequence ID" value="KAJ3223821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXC9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013918">
        <property type="entry name" value="Nucleotide_exch_fac_Fes1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08609">
        <property type="entry name" value="Fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nucleotide exchange factor Fes1" evidence="3">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="320" mass="36513" checksum="84EA2B95C5C32CA5" modified="2024-05-29" version="1">MPSQAELLHWATKNSINEATKSEDPTVTKEMEKLDPKWIDIILGKEDSISMKESMESAVDESLPIDVRVSSLDNFEMFVENLDNANDLKILGLWKPLLNLLQSETVKIRMMAAWIIGTCVQNNAKAQNDLVEMNGLETLIIHLKSEKEISVQIKLLRSISSLITSNATCFKLFYSSKGFELISTFLQKIDSEFFLDDSTEDITTVVRNFKKKLIYMLNFLLSTEESKLNVVTALACQKENLFEVVLNLFGRSKYDDVEFVEWGLKFISHMLNLEKNNKLDSVAESRVQLKLNSVLSEVQEKFKDDAVIVDLILKINSDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXF8</accession>
    <name>A0AAD5XXF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Wilms tumor protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_000815</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000120">
        <property type="protein sequence ID" value="KAJ3223703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXF8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000063">
        <property type="entry name" value="Wilms tumor 1-KTS isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056436">
        <property type="entry name" value="Znf-C2H2_ZIC1-5/GLI1-3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23561">
        <property type="entry name" value="zf-C2H2_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="359"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="393"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="423"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="484"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3223703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="611" mass="69384" checksum="5430F50BE3830918" modified="2024-05-29" version="1">MQMNDSDSGPRQAQIIQSDQSMMLNANLPVNWGNLHRGPSVIRPDRHRRTTSQDSINVSTLHRRALSLSQLNSSVQPIQLPSSNKFTTIPLPVESQLSFSYNNNNNNNNMQPQHHSLFSLNNSQINSHNRNRLVGHKRAVSVQHQYIDRPSSPLTQNNIINSGHELFTHHRSQSTHSNASSIDFMSGYGDRSATPFSTTSTYNNMASYMNTATPATLPSPVVGSSLPTDKSQNYRPLYPEVVNNINSGINSIQLQNNNNQNFENFTGYSSNDIITADNFNEQLTNNNWNGHQRQQHLNSLNEEDEPSVFENLVPVVNKIFTEDGIKTCLWADCDHIAISNKDLVEHLSVEHILVKKGNYVCEWKDCNRGHTKGFAKRHKLLQHMRTHTGERPYLCTSEGCGKRFARQDGLNTHEKTHLDVKPFICNHPNCGKAYYHSRSLRKHSRVHQNDDNIPLGDVDTEENIQDFQSDIADMVDSGNQSHLLSMSNQQQSQFQSEQQENEQPTYLYSQSHFQHSLQPQQTFQFRPQQSNQNNFSNWENNNTQHQQNISNDNQEYRSINLPRSSVNNNCVMGGNSFSLRGQSNSTSNFFSPAELVAYGVPGNNGYDFNQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXN7</accession>
    <name>A0AAD5XXN7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DEK-C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008233</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000089">
        <property type="protein sequence ID" value="KAJ3224552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXN7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000779">
        <property type="term" value="P:regulation of double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044198">
        <property type="entry name" value="DEK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468">
        <property type="entry name" value="DEK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468:SF1">
        <property type="entry name" value="PROTEIN DEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEK-C" evidence="6">
        <location>
            <begin position="493"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="394"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="405"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="550" mass="63010" checksum="D78643F65615F5B3" modified="2024-05-29" version="1">MEQPAEVTEVFANEIEQNIESCSSLLPIKRKPGRPKIILDLKNEKNITPASVITESSTPQEEKKLAGRGKKSFQNSNLVINMVQSEIVPISGSKRARTSVQRLEYDDFRKNITLFSNGIGTSFRDIKQICKNIQEEKFEKVFKSLYTTLFGGKVSQKNFRSDLLKFNGIDQEKNDKDVNSILTKLRSWTFANLKLLCKALSIDKSGESEKYDVDTSDEEFFAGVHSSHSDQNLNNLKLTGYDLFLKEKLIMDPMEITAPVKEDNLYLWNLLTADEKAEFEAKVSSLKKRPGRPRLKEQIDPINISTVTNEKPPTTNSPSRRISIRIKTTPNYVLPELENANANSFSGKSKSLNEIHETVDNSEHKQEKCEFIAKQTPSTYAPLRNSPFLLNEKEENVNDGSPQGSKSQSTLSVSQSVTPSKRSVRARTVSKNIPFYYEPDEEEEDEFENNFENSPKKKQIKMDEKTNQKNFLSSSIQKEEHFRRRKLSYHNLFPDDDEIVEAIHFLLVNDDLCNLSINSVCYKLESIFKYEMKLKKPFIRDSVDYFLVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXY9</accession>
    <name>A0AAD5XXY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cell division control protein 73 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_006883</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC73 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000622">
        <property type="protein sequence ID" value="KAJ3214417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXY9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11990:FF:000002">
        <property type="entry name" value="protein CDC73 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11990">
        <property type="entry name" value="RNA polymerase II accessory factor, Cdc73 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007852">
        <property type="entry name" value="Cdc73/Parafibromin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031336">
        <property type="entry name" value="CDC73_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038103">
        <property type="entry name" value="CDC73_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466">
        <property type="entry name" value="CDC73 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466:SF8">
        <property type="entry name" value="PARAFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05179">
        <property type="entry name" value="CDC73_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Cell division control protein 73 C-terminal" evidence="7">
        <location>
            <begin position="234"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3214417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="404" mass="46208" checksum="CC8DB7D36FDE7249" modified="2024-05-29" version="1">MTNLINALRLNDCKYLLLDGNNEETDSLLQTSKIKVENNVFDLTEQSGYKTYSNSSIINFIINKDLPHQQYIKNCSDSGNFQFAVSFMDRKDLIELLDTKLEINLSGNNDLKAGEKRNRLENSEKLELINKDKAEVSLINEKERVIRDRKNVMAVRGQRNFTKFQKLGAEFFDGKDKTKKISSSGLKKSDPRMKDKKNTSLSKVNGSGNNEKKQKTRHGNMENGGSNTGGSKGIPIILVPAGMTSCLNIYNVEDFLCEQKFIPSDVIRKSGKAKPLSVQLKRKFFSGSNGTSSNSGKNLQNFLVYDNVDRFTSSEWDRVVAVFALGQEWQFKNWKWSKPVDIFNHAVGFYLHFSDEPVKDIVKGWRVHILTIDKLRRHLDVQVVNEFWRLVDNFVQTRKPMLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY16</accession>
    <name>A0AAD5XY16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">USP14</name>
        <name evidence="8" type="ORF">HK099_008213</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000882">
        <property type="protein sequence ID" value="KAJ3210582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY16"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000931">
        <property type="term" value="C:gamma-tubulin ring complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033566">
        <property type="term" value="P:gamma-tubulin complex localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022214">
        <property type="entry name" value="MZT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12554">
        <property type="entry name" value="MOZART1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="7">
        <location>
            <begin position="1"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3210582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="436" mass="49487" checksum="A542735F2C7C77EE" modified="2024-05-29" version="1">MAASLQCLRAIPELSLALEGTQLNATGDQLSGLCTSLRELLKQISKASDTVHPYAFVHLLRQVLPRFNERTAQGFVQQDAEEFWGELISVLRTRLHGFDKENKINETEKFINQYLSGEMLITLKCDEAPNEEPTVSTDTFQKLTVNIGSGVHTYMVTDIQNGLTQPVEKNSPSLGRSAMYTQTSRITRLPYYLVTNFVRFQWKASDNVKAKILKRVKFPFELDIGLCCTHELQEKFAPARQKLKELDDKRADEKKLKKDPELLAKEEAEKANKRKGSKVLETHQDRLKIYEALGIDKSLREDIGANVSGFYDLVAVLTHVGRTAESGHYIGWVKNENGDWFKYDDDKVSPCSQEDISKLEGGGDWHSAYICLYKSKIMDKENEIEILSEIARLLDVDIDRESLSICMKLCENGVNPEALAQVFLELKSDSQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYJ6</accession>
    <name>A0AAD5XYJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYJ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055336">
        <property type="entry name" value="At4g00755-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012331">
        <property type="entry name" value="Clathrin_H-chain_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39741">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39741:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="626" mass="72627" checksum="7D8D6712D0F88B33" modified="2024-05-29" version="1">MLLKVLPDELIFHIFRYLDAKSVSNLFLVSKNWKVYASHEILWRELLLRNSFFKIIDEEDLEVKLPRILPLKTIRVSDIIANINSLNTREEESNTLELLKDRATERLLQEPKNENLNVSNSEKKNIFVDEWILKDNIEFFKETCELTKLVELEPSQIIGEGIYASSEDHESQSINETLELGNTFWSSKGSADEFSFEFLRYKLVQPICVISQIELIPFKAAFQPGGPIYAPKYISVSVSFTPNGNDFHYTSELFAVKNINKVQTFNIKPVFVIGGYLQINLFGRNTRQPADQLYYTVLQSVKALGLPIGCFLNLKTVAKSCIELSNKLNCKWEGKFQSFQNGGVDNNIKHLERFFRPFMSSREGQNNLKSELKNELRNGNWKYVARRIAAADEGVESEFRSQKYLTWFEKNAKLIIENKQEQETSSEDEEEEQECQLKVFIGPQSNTFTEPILYYLKFLIKNGHTLTQYEAERLALYSIKKNSYQVFYNCLINEKFSSTEELGDLFRSIYLTLALDIYTRAMVVDKMIDCSLQLKRYNGAVHLLSLGLNIQEFEVAMKKVYQFHSSFVEMVKFSVYAMRQNNSPILRTTLMESLGVAEETLHLPDWELERYIFGWAEQKENASPNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYP6</accession>
    <name>A0AAD5XYP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_007097</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000661">
        <property type="protein sequence ID" value="KAJ3213967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYP6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00029">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000180">
        <property type="entry name" value="serine/threonine-protein kinase STY46-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050940">
        <property type="entry name" value="Actin_reg-Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46485:SF5">
        <property type="entry name" value="CENTER DIVIDER, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46485">
        <property type="entry name" value="LIM DOMAIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="13"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="12">
        <location>
            <begin position="337"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3213967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="424" mass="48133" checksum="D50C391B71EF46E7" modified="2024-05-29" version="1">MEKKMYEIEWEDLTEWKEIGSGAFGQVYKAEYLGTEVAIKKFMDIKPNPNIDLKKYIDREVGILQECRHPNVVQFMGVCIHENKCYIVTEYVGGGNLKELLLDATKNLDWREKLSFAIDSARAMVYLHSREIIHRDLKSENFLLTDNKRLKVCDFGLSRETPITPEDVQSLSFCGTDAYMAPEMMLCMPFDTSVDIFSFGIIILEIIFRVVADTSMNGIPSVHPLLDRVIPDFYETALDCCQENAERRPAMKDVLKRLKRIEQSLLSATSNANVGYLTESQLHLTSPSIEDSTTSLNSSVNLSQSFKNKIGFTKFEKIRNSNESDLDNSNKFVGAVPHRFSLMYNLTKSRCNVCSRGFGMTGRHLICDDCGCQVHKRCGIHAEPNFKDVDETSTVINITRSLRELRGLSNKSSIIGSGRRESKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ44</accession>
    <name>A0AAD5XZ44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ44"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="13522" checksum="FAE09344E88FB7EB" modified="2024-05-29" version="1">MKIKETDVFEKLTPVPFQIILNDQILHGNERVLQETREYIQSIQEISPEKRVYMDESFIYDNEAPSMDRSMRGKHISRPRKRHGKRWTFYLAIRSTGIVYDPLISSESAKDETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZL2</accession>
    <name>A0AAD5XZL2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005448</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000423">
        <property type="protein sequence ID" value="KAJ3217514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZL2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="88" mass="10374" checksum="48AB815E27692C8C" modified="2024-05-29" version="1" fragment="single">MILTIFGIDTFLGRSLYNYLSSYYGTKISFILISKFNGYKLDNKDSPKVVWLYEINPSVIESMIYSDYVLYTMNELQYKAENTINYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZR0</accession>
    <name>A0AAD5XZR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Lariat debranching enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DBR1</name>
        <name evidence="15" type="ORF">HK099_001317</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lariat debranching enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000136">
        <property type="protein sequence ID" value="KAJ3223276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZR0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008419">
        <property type="term" value="F:RNA lariat debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00844">
        <property type="entry name" value="MPP_Dbr1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000035">
        <property type="entry name" value="Lariat debranching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007708">
        <property type="entry name" value="DBR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041816">
        <property type="entry name" value="Dbr1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849:SF0">
        <property type="entry name" value="LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849">
        <property type="entry name" value="RNA LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05011">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01124">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lariat debranching enzyme C-terminal" evidence="14">
        <location>
            <begin position="279"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="254"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3223276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="354" mass="40694" checksum="6B079E47EF7EA1F0" modified="2024-05-29" version="1">MVRIAVQGCCHGELDKIFTAIKHIQKKENVSIDLLIICGDFQSIRNTADLESLACPEKYRSLGTFHHYYNKLKKPPCPVVFIGGNHEASNYLWELYHGGWVASDIYFMGFAGVINFGGLRIAGLSGIYKQLHYDCGHFESQPMVGDDMRSIYHVRKFNIFRLAQIKEPLDIFISHDWPRGIANHGNHEKLLSTKSFLAEELRTNTLGSIPNEFLLKRLKPTYWFAAHMHVLFAAIYEHNKVEVSSKAVTKNPDEIEIESDEEIDENGTENQKKKESVVKEEKATPMRKFTKFLALDKCVGDRSYLQIIDLPTDASEPYKFEYDREWLSIMKATNSLISFERRQPPLPEEAETQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZR8</accession>
    <name>A0AAD5XZR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Groucho/TLE N-terminal Q-rich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001270</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat Groucho/TLE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000134">
        <property type="protein sequence ID" value="KAJ3223348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZR8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005617">
        <property type="entry name" value="Groucho/TLE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009146">
        <property type="entry name" value="Groucho_enhance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10814:SF21">
        <property type="entry name" value="PROTEIN GROUCHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10814">
        <property type="entry name" value="TRANSDUCIN-LIKE ENHANCER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03920">
        <property type="entry name" value="TLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01850">
        <property type="entry name" value="GROUCHOFAMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Groucho/TLE N-terminal Q-rich" evidence="8">
        <location>
            <begin position="151"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="529"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="612"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="677" mass="75434" checksum="6749984605B6A86B" modified="2024-05-29" version="1">MTTANAPAVNSITSPPSTQQPNPQSPLLSASTSNLSLPITLPPLSNLQNSQNLQQACLNKIASLNKIQSPPNSTYPKQIPYEVGDKPISMNYSSNQRQIHSSQDDIKRNIPLSPQVQQDHHLLQLPSRQLLPSVQPMVQNVRSYPANNSKIFDYCEKIKEEFSVLEYKVENNSREKSELHLQYAKHWEMAYQLNAEVHKQVDINNRYQAIINQLLPMLTPNVQAGVRQDMESIKSITDSTLPPPPQAPVLLNDMREERITPPNGVVRGQLIEELDAKNRGRGRPSKVRMEAYKEELMHPQNSKRSRLDNEVMENSLSPRFPAQDSMLLSQQFQNQNLATQHLNTPPFISRRGSVPQIPPPRSPTSVSLPSVPRGLTLLNPDSVKSATPKGVQLIATLPHGEVVCALALSHPFHYVYTGGRGIVKIWDVSNMNENRKGINVGSLDCLDNYIRAIHITRDSKTMIVGGEARFIVICDISSGNPTITGNLQTPNQLTYALCTSKDSSVCFSCCSDGSINMWDLHTLQLVKTFDGHGDSVTCCCLTPDGQKLITGSLDKTVRVWDITEGTEHCQYTFNSQIFSLGVCPMEPIIAAGLETSAVDVRFLSNFDMNRTLRLHDSCVLGLKYSPNGSWFVTSGKDHKWIAWKSLTCETLFQQLENSSILSCDISRDGKYIVTGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y060</accession>
    <name>A0AAD5Y060_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL27m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000332">
        <property type="protein sequence ID" value="KAJ3219648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y060"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_bL27_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022709">
        <property type="entry name" value="SCAI"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12070">
        <property type="entry name" value="SCAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="189"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="189"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="402" mass="44626" checksum="172FE3D4F95BEBF7" modified="2024-05-29" version="1">MRKFTFYQSMPKVFPAPLVILMGPTEYPSTIKDTTQIGSLFTLFLHAPIKAFAFISETTQISSEVWAQCLTQMNVVEKTILEVVDNNLNNLGNHFPVSQPSLPLPLLQSPEILQSLKDLVNLAEVASLYNFSSPTLPGRSSVTSSQPLNSVQTPTITTANVEKLESANQNSTKDLFAVPVSNSEKVASTVNLTSDNKENTISAPTESLQNAEALNSNTPSELPKEGVVGQESAVSSNDEKNATKKTGGSSRNGRDSNPKFLGLKKNDGERVSNGNILVRQRGYKWFPGKNVKASKDHSLHAMTTGKVRFHYDLAKQKRYVSVDDGTLSRDLLPSRDEMKKTLSDRVNAEKYLKLKPIAKYRYIRGLITEISKEKQLQKESFKYKTCTNKGFRKFNLVDLTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0G1</accession>
    <name>A0AAD5Y0G1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000208">
        <property type="protein sequence ID" value="KAJ3221797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0G1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="23"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="615" mass="70892" checksum="477606870790DAAB" modified="2024-05-29" version="1">MSNFVKEDKPATAVENDLVPKNEKFGLNVTEEKGRCLVSKQDFDTIGTSILSTKAYAFSIFDKYKKRYCGVCLKKSELPQFTLHCNLCDSIYVCSANCLNELIANGHHLICRSLRRIATFKHSIHEKGVIKILLFLLKQRLFEKEVFKLPSFDGFQADENVYTGLKEIRKFLNDKENKFSKNALNGPNLQPNGNVSSAIKLKKEGGEDIDLTLLVKSPEKTNTLKKEENIVFNSNWEQMEELQSHYKNWLEDDKKEWKKANSFVFKIIEESQVLEDKKELLRILSDIEIQSKKNANTNKPSTSNTATFDLMEFHSCKPNCECIHDGLHITVKSIRKIKKGNITLDIHSKTFVLQGEDLTISYIDVNLPVQARRQKLKQEYFFICNCDRCVRESANTKSKQKIQYQQQKQQSPNLSSKQKRNSKSRIAGTLIEAGDNSSLNYIQQLEDQIQINIGEQSVQLNLNESMRNGNNRNYNQSGYLYQKEMINQQQEFLLQDGFQNFNIDNHQSQHSKQHSNYIHPGSHFYSPPLQPNPQQQQQQQQQHPQQFYSQAGSSSAQIIDQNQPYFWLSPPGMVANNNGLQTKNLNNNGIGVGYYNNIQPNNNFIYQQNPPPRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2E9</accession>
    <name>A0AAD5Y2E9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000061">
        <property type="protein sequence ID" value="KAJ3225436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2E9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF190">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="108"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="704" mass="79862" checksum="09FC677EE9EAFEAF" modified="2024-05-29" version="1">MKINVVYNNIIKEIEIDPLFDIGNFRECLTTNLNLDSDNHNILIFFNETELISVTQTISEAKIQENNSVYIQLTPKNFSKHNLPSPTNNNCPTDKNKHSKSFLSNKFDVLSIIISLLSKNELFNCCLVSKAWHTIAVSQIWKSVVIYSENWDLIKPIVTKANDNYKKLIQRFILKSSNENPLLDTKPHQLRRVLEKSTNLTVISLNTPSINDDDIWVISMNCKHLSIVNFFSVDVDYARITDEGLQALSNCRMLKMLFIRSSWIRRKQTGSQSEKMRDPFQSTSNQNFAFTDWGFKKLLDSFCGRLLGFGLEWTGGSCSPSDGEDSAVFYSNYGTKLADVLKDLFRLNLNLQEFYLDWPLPIESVLEHSSNFSKNLKKIKIGNAQKVDALIKIVNNNHNLQYFSLYELNATVDPTVLLEPFIIDTPKHNLPTMDVNSFNENYFSSQQSVFSSPASLASSFSSSFYSTPTSLMIPVERKEIVELELDGVGFISNLLTSITKFSYLKRLIISPSRRAATLHHFMTDDLVGEVAKHCQQLIYLQAPIVGDAPLVKVAENLKNLEYIDLVSGREISDAALILLSKKCVKLKDVFLGSAVYISDNAISVLARSLNLTLNRFALPFGNQRITSRSLNSLTENCLNLEKLTNLPASIEFNFLFEKLPRLKKLIILGVCQQINLTGRGISYSRLEQDLLKGKCKRLKQIVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2M1</accession>
    <name>A0AAD5Y2M1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000080">
        <property type="protein sequence ID" value="KAJ3224816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2M1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055323">
        <property type="entry name" value="C57A10.07/YOR238W"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28110">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28110:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="30789" checksum="DD24D7312C11997D" modified="2024-05-29" version="1">MKKKTSVIWTFVILILLISLLTLFGFNFNINYDFINITDESSQDNSFKSGVSKINKFDLNENIDFDYNNFTNLIIVPGGQTRYSAGPKSEGQSYYEVAKLMDNQMFNNREFLNSVTTEEFAKDSFENLLFSICRFKEFTNFFPKTITIIGFKFKKFRFENLHLKAIKFNVKNFEYIGFDLPLQDRRTAEEGEKKFSVLPFQNDLYGCRDPLSRKKKNRNPFKRVSNPYKETCPELRTLFEYCPEGIKSNINYFIDQTVCFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2R8</accession>
    <name>A0AAD5Y2R8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GUCY2G</name>
        <name evidence="14" type="ORF">HK099_005577</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000044">
        <property type="protein sequence ID" value="KAJ3226108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2R8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="166"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="13">
        <location>
            <begin position="619"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="513"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3226108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="798" mass="91253" checksum="031DFFF052373B13" modified="2024-05-29" version="1">MEAFFSKITSTVSTQLIIAGAMGAGAILVLTIIVSSMIYCIKKNKRNTSIKLQEKHKREELLKDFIIQLDEIKPSEPVLQWVWQQQREHYQKVEPNWNSKNLLDGEAIITKTIENQQKGLLEKSNNNKNNSKTSLNRDELKPKKVETTFSQLRYTFISKKNGARITCLKYKISEGMLETVEENPDPLSVVVANSTSKLNQVGHFDEEKSIGQKLELRLKDENELKWLLDLKQLKHKNIGEFLSVALRQPLVHICYEFFGNGLIEDLIVKQRNTLSFNTRLLMAKNLLDGLSFIHESFIQSHGSLNLRNCFLDETFNLKITGFGVSQFVNDICPPEEEKNPVPIEKLFVAPELVSKYPNLGAGTQQGDVYSAAMMIYTILYQKIPFEKTKDLKEKVGRIVNDTETAVRPNLTNQIPAEYNELISLSWKFNCEERFSLPKLMLEFDQLANKSVKNYLQEAVPPTNTLILSNLDRYMHDLESSLFITQENCQKIIYQKSIEVDSLEKGKKSLEFNLDKELKIKKTLNLKLEKLAQESDKIEKTSISNIKAREEEIRNLKRELNTQEMETLNLEKDCTEIKNFFLPKPLGEIAQSQIQSPRKKDSPQRVNLEYNHSSSYEGVTIMVVTIVHFNRLVEQLSNSHLMLDLLRIYHDSIDMLLQSYPKIYWIDRISDTCIFVSGAPDENYRHAEDMADFALKLENWSRQTDLEWILGQGGRLFLRLGMHSGPITAGVVGRIPKFVLLGETVNLAAKIGAECSADELRISSVTKAILSNAHGYIFVENVDNKTKKNFTVLVGGPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2V2</accession>
    <name>A0AAD5Y2V2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytosolic carboxypeptidase 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AGBL4</name>
        <name evidence="6" type="ORF">HK099_007023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2V2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050821">
        <property type="entry name" value="Cytosolic_carboxypeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040626">
        <property type="entry name" value="Pepdidase_M14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756:SF9">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18027">
        <property type="entry name" value="Pepdidase_M14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M14" evidence="5">
        <location>
            <begin position="129"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="45957" checksum="752A03CD7FFB63DF" modified="2024-05-29" version="1">MLKNHTKKLTPITGPHNSNHSSISSGNTEGNYASNLKFDGSFECGNLGKVDIISEFEFDINIRPDTSNLRQRVWFYFSVSNTQPGQKVILNIVNFSKTKTLYREGASPVVRSKNKPECFDDEYFFAYSFPYTYTQLQDYLNEISLRNLPFFDRELLGYSVEGRRLDILSITSISSLTTEPKRTICITSRVHPGESPSSYVCQGIIDFLISSNPKAEELRSKLVFKIVPMLNPDGVFLGNYRSSSLGFDLNRNWQNPSKEFQPEILVTKNEFLKFKDDPNLNVEFFIDIHAHSTMMNGFMYGNTHEDEENREAQKVFPLLLDEKVFDFSFKNTNFNNDSVKAGTGRRALGDFLEESLCYTLEVSFFQHHEVKGEDAVKPYTIQKYQELGKNVILTLLDYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2Y9</accession>
    <name>A0AAD5Y2Y9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BRO domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BRO1</name>
        <name evidence="9" type="ORF">HK099_006642</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000059">
        <property type="protein sequence ID" value="KAJ3225504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2Y9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF30">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="8">
        <location>
            <begin position="7"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="814"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1093"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="591"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="814"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="911"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="926"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="945"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="997"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1093"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1128"/>
            <end position="1144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00041284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1144" mass="127792" checksum="2C09B172D7199865" modified="2024-05-29" version="1">MSTSQSPLLSPSMKSTDQVDFIAPFSTYIQNAYQEDPSKYLGEINTLNKLRIDMTDAGNDLTGRDILYRYYGQLDLLDLRFPIDEKNIKISFNWYDAFTGVEVSQYSVAYEKACVIFNIATVCAKIAQSQNRFEPAQLKLSFNYLQCAAGLYNYINDNFLHAPSVDLSRDSIKAIVDIMLAQAQECFIEKVLMEKKKGSIVSKLAAQCSNMYSVAGDGMQEESVKGQFDKHWFEIVKIKAKYFQALAHYHKTLNDKSQKYGEDIAHLTVGETLAKEAYKAAQSFGSGGFFKSEDQTSASSALMECTKVLLNLLTERKVSSIKDNDLIYHDLVPNLDTLNPIEKVNATKQLAFADICQNGASDIPNIIGPDIFQKLVPLSVHESSSMYSEEKAKILRSQQNIVDAANQELQATLDSMNVVSTLDKLKKSLKNGMDNYGLHLPNEALGWCSKVRGEGAANIDELAGVVEVLKKRIAETMDECGLQLDKEQHDCETLRSKYLDKWTQPVSATLTSKMRQDLNQNRNTFEKAKSTDSQLFSRILDSQPVIDILKRPIEEVEAVFASKVLEQKESSTLIDGDGFNVLGEQVMIEKLEGLVHRLQLLKKERNEVLNELKEKIHNDDISSLLLLNKNRESQVFQAELVKFKTQTQKISNTLNQQKQLLSEASKEIEKLVQTSVTFKNLEKKESKIYLVLKEWKKGFDLYKEALEGLTNGVEFYSNLQEIIESLKKEIFKFVNNRTEERVLLIKRIDDQQAEIGQRVLKDQLYKLSINNPGATGSVTSNPATSPYVNNNYSVQSSNAKPAAALYPSLNGPLQGSYGNSTSPGGQQSYPSLNSLPQNYNQTSVSYPLQQTSISSPSTMQSTTSGPSNPSYYNLTHPQNYNNLNSQAYASNYSNTPRPDHPTSGPPASYPTSTSLHTFPTTTSYTNYSNAPSQGNNYAPAAPASTYPNNIPLQASSNHQHANQPPTQATYGGSSANQSYYQPNPTGYPVPQQQQPPYGNSNTGSNQINKQPYNSSLYENKQSLGGLPPAVPPKQASYSTYQQPVSQPLYQQGANASYQHHQNNAATLPQQHFSQPPMPPHSQQNYNYYQQSYNQQPPVQTQQHQQNYSIQQQQAHLQRPVYGVPPPSGNNYQNQQSSQQNGSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y329</accession>
    <name>A0AAD5Y329_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y329"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="49"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="185" mass="21327" checksum="E8C2E812B9D6633F" modified="2024-05-29" version="1">MQNFSTKINYLTKFTFLTTQDKKTYSTLSENSKNNDLYQVISKDLKYKNKLKIGKITNKSHPAYNQFGLFTLNKLNKEEFIIDYIGVVSSKPSETSDYCLNFEQGLNIDAEFSGNEARYINDFRGIEKKPNSYFKTYIDKSENNRVKIGVFTLSEIEKGSEILVSYGKSYWKSRGNGEQIDCTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y391</accession>
    <name>A0AAD5Y391_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y391"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="21915" checksum="4F712388698F834F" modified="2024-05-29" version="1">MDYVVKKSSLKQNKVETLYIPGNYAKKIKSNFNIETFDQKLKFNLENLLSKKNEDHNLYKTGAVKIRKGYEIFQLKKKMNLDNSVVNKHSKYHCCYSDKRFKKIEEEIVKANLKHTKKEVSFCPLSEMKSPKSIENVQLSALENKEFEVFGDSDEFYSDSEIDYSDYSDDEVASIEIRMGLGLIDTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSX9</accession>
    <name>A0AAD5TSX9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002035">
        <property type="protein sequence ID" value="KAJ3199797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSX9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000011">
        <property type="entry name" value="Fragile histidine triad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051884">
        <property type="entry name" value="Bis(5'-adenosyl)-TPase_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243:SF1">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="50"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3199797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="127" mass="14833" checksum="D96CE296ACFC1C29" modified="2024-05-29" version="1" fragment="single">PRFSELDNEEVVDIFETVQKVSKVIEKEYNAESMTLTIQDGPSAGQTVPHFHVHIIPRRKGDFANNDDIYNAIDEKSKEALIELQKKKVKVDNENRKARTQDEMAKESEKLRLQYFKDCQFEDIWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTH8</accession>
    <name>A0AAD5TTH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxymethylglutaryl-CoA synthase</fullName>
            <shortName evidence="5">HMG-CoA synthase</shortName>
            <ecNumber evidence="5">2.3.3.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-hydroxy-3-methylglutaryl coenzyme A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002403</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10188"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57286"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. HMG-CoA synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.10" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010001795">
        <property type="protein sequence ID" value="KAJ3201020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTH8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004421">
        <property type="term" value="F:hydroxymethylglutaryl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00827">
        <property type="entry name" value="init_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000008">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013746">
        <property type="entry name" value="HMG_CoA_synt_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013528">
        <property type="entry name" value="HMG_CoA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010122">
        <property type="entry name" value="HMG_CoA_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01833">
        <property type="entry name" value="HMG-CoA-S_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323:SF2">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08540">
        <property type="entry name" value="HMG_CoA_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01154">
        <property type="entry name" value="HMG_CoA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase N-terminal" evidence="6">
        <location>
            <begin position="10"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase C-terminal" evidence="7">
        <location>
            <begin position="183"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3201020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="458" mass="51768" checksum="C97FA75655E7961A" modified="2024-05-29" version="1" fragment="single">MLGNFTHSPPPNIGIVAIEAHIPKKYVNQDELEDFDGVSKGKYTIGLGQLNMAICDDRHDINSICLSVVSSLIKKYKIKFSDIGRLEVGTETIIDKSKSVKTVLMQLFKESGNFDVEGVDTTNACYGATNALFNAVNWIESSYWDGRYALVVSADIAVYKTGNARPTGGAGAVAMLIGPNAPIVFDNGIRASHMDHLYDFYKPDLHSEYPIVDGPLSNKSYITAVDATYNLFLNKIEKRYKDTASKLNSENLADYFLFHSPYVKLVQKSFARLAFNDFKRHPENEKFSNLGLEKYADIPLEETYTNKDMEKIFMNLTKKDFLKKVDPGLTVSKNLGNMYCASLYGGLVSLIGGVDSEDLQNKRIALFSYGSGMASSMFSMKVVSSTEKMKEKLDLEHKLKNRTKITPQEFNSIMELREKCHNMKDYKPVGGIQENLDMWKDDYYLDFVDEKFRRNYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTH9</accession>
    <name>A0AAD5TTH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002355</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPF27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001777">
        <property type="protein sequence ID" value="KAJ3201132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008409">
        <property type="entry name" value="SPF27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13296">
        <property type="entry name" value="BCAS2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13296:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SPF27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05700">
        <property type="entry name" value="BCAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="125"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3201132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="196" mass="23300" checksum="A690D107C4864012" modified="2024-05-29" version="1" fragment="single">LPYIDLEYSNDQRLAQEVDLLIEKEMKKRKLPAEPKEYEFKNNSSSSINKYLERISEGEKLDSINVSRLRLLEPSNFDVKEWSESLDNSYVQLEHQNLRMLNLEFLSKFGQNLWLIANFNLESYLKVLNSKLLEVKDEIKLLNRKRKEDQVKGGDKLYILKHKKVDLINNLNKVNIAKKKLHLEVEKLRKDLEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTP6</accession>
    <name>A0AAD5TTP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001596">
        <property type="protein sequence ID" value="KAJ3202266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTP6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="124" mass="14360" checksum="54F54DD238E91386" modified="2024-05-29" version="1" fragment="single">SMGWCELIMRTNGGSICMLLSATKPKKEENIPRVKKRKKPEKTEYFQDNLEDLHSNKVYINPNKRTCCIVLVGNGNKLRYTQMQRRKESGLKRYQKNRQKLSNQVACLNTQVSVALQKRNLSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU09</accession>
    <name>A0AAD5TU09_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001201</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001316">
        <property type="protein sequence ID" value="KAJ3204297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU09"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="39"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3204297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="75" mass="7928" checksum="1F617D61E12688DA" modified="2024-05-29" version="1" fragment="single">SFIGIIVGHLYFFLDKVYPATNGGQRLLNTPQWLKNLVPDAVPKGATRGEGPGNPNSSKGGSSSSWGRGNRLGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU46</accession>
    <name>A0AAD5TU46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001257</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001336">
        <property type="protein sequence ID" value="KAJ3204133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU46"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF210">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3204133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="324" mass="35584" checksum="D1E3221365E7EF22" modified="2024-05-29" version="1">MDEKLFAFLLAFIASMGTFVGGVLVCIFSFFNGLNSNSNKLIGALQAGSGGVMLYMTFLDLVPEAIEKIGNKSTMTWFFVGVFLFGILENFIIPEEHNHDHEGPEKIEEEKSVNKFEEKLNSANNDESEKDPALKKRKKKIKESASVKTPSQNKVTDKRILSKVEKELKRTSLITFMAMFLHNVPEGLGVYLATLANARLGVELAVAIMLHNVPEGMAVALPLMAATRSYSYVLWMTLLNGLAEPIGVIIGGFLLKDIMSPVILSKCLACVAGIMACISLHELQPTAIQYSGKNLATVSLFSGMFICFLALETVHSFFHDGHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV03</accession>
    <name>A0AAD5TV03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001090">
        <property type="protein sequence ID" value="KAJ3206926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV03"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042080113" evidence="1">
        <location>
            <begin position="26"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3206926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="271" mass="30889" checksum="729BA44821B3A5F5" modified="2024-05-29" version="1">MKFFKNLNSIILSIVLLTKTGNSQGITLTQDQSDLQEVLDYLGNSQGSLKMASRTATMGLISLKEIRQNSNPSTPTCQDALKEVFQLYQSYCYFPGRIDYSENNMRSLQNWIWPLCNLNDCAKISYNWQRPLIEACPNENEIYVDNGTLTGLTRSFFQNYRLEKQGGSSQICKMELTQDGVYCAARFFDNLQKMWIKGISVSKVFGYCNESCAWAMSRAICDSCFKKFSTYILSAPNSHQISPLIKNVIGIDNEVQFDQFKSYLKTINNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV10</accession>
    <name>A0AAD5TV10_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001006">
        <property type="protein sequence ID" value="KAJ3208224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV10"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031991">
        <property type="term" value="P:regulation of actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051492">
        <property type="entry name" value="Dynamin-Rho_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN FUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834:SF20">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="2">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="275" mass="32657" checksum="443D1F7383E19D65" modified="2024-05-29" version="1" fragment="single">MPSNDTSSLHSKKFVSYIKIFENLKLDEKLFTNLEYEIKEKIFLLIEKLKDMFKGPFLIIKKRDDKLLDYDRAKLIKSRGEELDKSLKESCEVYELLNSQLIEELPKFFNLTAKFLKLIESEIIKNFTKFYEQVSTSLEKFAEEIYNLKKSDLQNFDTVREKFFFNFKEGSELEICSRNILLLKKWRILIWLEEEFTLKGGFLSNIDYSFHAPDKNKNDPFEAESSIKGTVLYDFKGEYEDEVNIYKGDMIEIILETENNKREGWSLIFFENSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV69</accession>
    <name>A0AAD5TV69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">LSM1</name>
        <name evidence="8" type="ORF">HK099_000247</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001047">
        <property type="protein sequence ID" value="KAJ3207569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV69"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01728">
        <property type="entry name" value="LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034104">
        <property type="entry name" value="Lsm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="7"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3207569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="136" mass="15456" checksum="2AD68713F9F497FC" modified="2024-05-29" version="1">MGDYFLPGSASLVDLADKKLSVSLRDGRTFIGTLRTYDQFANLVLQDTIERTIVGDIYGEVQHGIFVIRGENVVLLGEIDPHKEEISLSNLKKVTPYEAMSAFRDEKKLKKQKDFLNGQVLHRLGFDNEPIEHDNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV71</accession>
    <name>A0AAD5TV71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001082">
        <property type="protein sequence ID" value="KAJ3207060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV71"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="22540" checksum="340989D836D4EEC6" modified="2024-05-29" version="1">MNANNEDKNKLSIDTPLDDFSVYSQKERRAAHLERKRAGDEIHNEVVRQGLESAAIWTTGAAAISLYLHQSRRSALYNNVRPAYKIFLVTLVGTAAFFTRTDISSMNEDRKFSAQYSIHKPSEQALEEGVDISTPFSWTKEGIKASLLRNRYALVGDINTSQKVINSRMTAQSAVLLGLAAFAGVSAMNVAPPKNISIESKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV89</accession>
    <name>A0AAD5TV89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ras- protein Rab-7A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RAB7A</name>
        <name evidence="5" type="ORF">HK099_008635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000972">
        <property type="protein sequence ID" value="KAJ3208866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV89"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF20">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB-7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0636">Prenylation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3208866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="166" mass="18765" checksum="B8B242B63F6393C3" modified="2024-05-29" version="1">MNQYVNKKFSNSYKATIGADFLTKEVQVDDRTVTMQIWDTAGQERFQSLGVAFYRGADCCVLVHDVTNIKSFDTLESWRDEFLLQASPRDPDNFPFVVLGNKVDVGDQRRQYFETSAKDSTNVEEAFKTIAKNALLQESDVELYGDFTEPIKIGEDNEAQASSCSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVC6</accession>
    <name>A0AAD5TVC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HHF1_2</name>
        <name evidence="15" type="synonym">HHF1_1</name>
        <name evidence="13" type="synonym">HHF1_3</name>
        <name evidence="15" type="ORF">HK099_002708</name>
        <name evidence="14" type="ORF">HK099_003379</name>
        <name evidence="13" type="ORF">HK099_003426</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002245">
        <property type="protein sequence ID" value="KAJ3198860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JADGJW010002217">
        <property type="protein sequence ID" value="KAJ3198978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JADGJW010000192">
        <property type="protein sequence ID" value="KAJ3222093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVC6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000007">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-T/Histone H4 histone fold" evidence="12">
        <location>
            <begin position="37"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF15511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3198860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3198978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3222093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="103" mass="11354" checksum="DF3D30BE1E62D35C" modified="2024-05-29" version="1">MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEETRTVLKSFLEGVIRDAVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWN7</accession>
    <name>A0AAD5TWN7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007686</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000769">
        <property type="protein sequence ID" value="KAJ3212643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWN7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3212643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="154" mass="17574" checksum="A0A720DD7FAB3947" modified="2024-05-29" version="1">MTVEKKNFNLATSELTLNHAKQLQTINKVVLNSHYDLKFSKNACNDLTLLGFFNDITSGAITCKKLDEKSIEIETIAVLKNYQNFGLGSLLVKDLLKNLSTLKFQKAFVKISKLNNITIELFKKFEFAVDTECKENVERDEDFVYLVKDIVAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWX3</accession>
    <name>A0AAD5TWX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000707">
        <property type="protein sequence ID" value="KAJ3213462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWX3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="185" mass="21665" checksum="443226505EF2FA26" modified="2024-05-29" version="1">MDVFLAVHKRVKLRPDQISQHLIKRIKREYEEHNYYEKKGAHSKSNLLLKEDILQTLKEITQQSEVDSISKQKDKEKDWIINVKEYIVSKKTEKPLNKETILKIFGKPNKIVTSEKSYEIPGFFQFNYILNKRSFSTSSTAKNGDELSSLLSEGYATLVGFCYNELICFRFVNGYMVDIKKIDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWZ9</accession>
    <name>A0AAD5TWZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">U3 snoRNP protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UTP20</name>
        <name evidence="5" type="ORF">HK099_007662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000762">
        <property type="protein sequence ID" value="KAJ3212818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052575">
        <property type="entry name" value="SSU_processome_comp_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046523">
        <property type="entry name" value="UTP20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011430">
        <property type="entry name" value="UTP20_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695:SF11">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20416">
        <property type="entry name" value="UTP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07539">
        <property type="entry name" value="UTP20_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2524"/>
            <end position="2544"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20 N-terminal" evidence="3">
        <location>
            <begin position="842"/>
            <end position="1488"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20" evidence="4">
        <location>
            <begin position="1720"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2312"/>
            <end position="2339"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="2565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3212818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2565" mass="293905" checksum="11C160A00B10B45F" modified="2024-05-29" version="1" fragment="single">MLARDLQDQFYPHFVLIFENVLLILNDADPTRLELIYNTIAHLFKFLSNHLTNDILVIFNMLIPSLKDNKSHIRLFSSQVLGFLMRKIKITSYDVVFQNIIISLNENSSEAYSDGIAGLFFEMVKQVNNTIHSKAKAVASTLFDIFFHNDKITGNDVAFLMLLKFCTLVGHHTSKENFSEIWELIKEKKAVTLVAETDVDSFLRIGKYFAVLYIFVTIDGGRKIVDRKILFQLIQHSIEFLLKLKKFEKFENSIKYSLQQMVKLTSSVFETSTLETALVYGKQTLDLIFNSKENVCIFAFCETIRLRKWIHFPKLITPRILSYLQTNFESDPVRSIVFLSNVFGLEFATMMDSVPKHMKSSDNQLNLNVTRAEDQQKIPLSELLISKYLKVLDWQNEASVVFEESSSIIPVVYSVLNSLNFLFVDFDNFFNILKENFISMVTSIEFLIQQKKDLENLKKAKILMILSANMLNTLVSKCLRLNKCLKLLELFDVIAKKYVKCNLGDGSSLKAIFEYLEALKSVRSVSKKIDLCFSVEQLTIMLPLLEDYVGSTNHLARLNALKIINCFDQSPLLNSATPCLLIQHCIDIEATPDELQSLREKTMHLRKLESLQCAKTCPSQYAYVAIKYCLALLSLNFMPFVEEVIQAIKKICDSDIKRFWEVYKLVIIKVKGSDSFNNLNDNVIWIPNFNKIADDQEIEDIVHTDTKRNNKKITFKNKQNKKFKSSNIDTADVAVHVLGIRFEKAYNISRNFMEVMFMDFQKACFKSIQEINIANYYLVLIKAIGNIPHIIDQRSAFLVPMFLELFDSKIKNGDFFLEDYTEEVISDGKQPKNNVNLVPDLRKQILEFLSMFSKVKHPQKLFKSSSLKNIILSLLSNGDSPIQEKAFDCILAYKNSSILSYTEFFKGLIDDERFRDSLSGFSLENFGAHIKDENRSEFIQVLARILYGKLINRKGRGSNKSGLKARRGAIFSFYSAFECNDHLELVNLMIQPFQKILQNDVEMKVEFSLNSLHKESLPSPKVQIGFLTVLEDFLKQFKTKAEPFLPKVLSVLINLLAISDSLLRKENVEDDEDVMEEDALEDNIEVHSIDILALKQFKNIRSLVIRRLKQIYEMDLSFNFQPYLASIFSSYIDARIAKFSTENTQAPSALMELIYTWANNRKYVLYLHHNKKLLPQVLNLLSAKKVQDSVVSKVLSIIEAIILVDAEVNGEENSMNDIEFTVSILDTLLVPEIDCLLLNLKVLLMNNSSNNEKKILSKLNYVNSISNRVLAILAKLSKFLKNSTHIKNLIEMMLPFLKKQTNQVPEKAKVEILTVLNVYLTTLDSHQRSNEEDFQKYFVVSSELFSALETREARNSVVSVFKTLSSIDASLKVVYVHVENLNAFSIKRLDEKDFDKRFSALKAISNSSNTLSPYQWLPILHNLLFHIQDVEEYSIRTACLNGILNLVEKAFADSTTENFKEVAAEHSFMNLVFNTILPYVKRGLRIKNEVVRQEFLQILCALVSSFPKHGQLVDMVVLLSNGNEEANFFKNIHHLQIHRRIKALRQLAEHSENGNLSIKNINTIFIPLVSHFIFETDRVEGHQLVNETIHALSSCAGVLSWSQYYAIIRQYFFVLKKKPDLEQIAIRVIVSILEKFHFDVSLPDSILASTATTVAVIEKKMDLDNHEEHLQVEEEIPMDLDDGKDVQEEDLNLKNYNLNSKIHSILCEKIIPDLHKLLAKKEDENLVVRVPVAIAITNLLKQLPSDTLQLLLPKLIFTLCNILKSRQQSARDTTREIVVKVALILGMSYIPFIIKELFNVLTKGYQLHVLGYTIHSLLVGIAPTIIGSSPELDSSSELLVKIFVADIFGEIGDEKEADELRGKMREIKKTKSYDSFELLSKMISMSTVTSLLLPLKEIMLETNNMKITRKVDEVLKRISQGLSSNSSVVVKDLMVFVHDLITENLSLAKVNDGSKVEKTNLEKNYEIKLKRPDVMEPLKYFQGNAFRFIEFGFTLLLSALRRELVDVRNDEHLAMLDPLIMVLGKALYSKHASVIVLVLKILAIIVKCPLPSLDDALKVIVKKVLSIVGNSVNSGSEVVQNCFKLLTIIIRERKNTDIKESHLIIILELLKPDLEEAERQSVTFSLIRAIISRKYVVNVVYDLMNDVAKVMVTSQSAQIRELCRYTYFQFLLDYPQGKQRFQTQWNHIIKNLQYAFESGRESVMELLHLILNKFPDTIIFEYSEVLFVSLVVNLVNDDSSKCRQMTGILLKKLFQRNGLDRSEKLLELADKWFEKVDQPELLRSAAQVYGLAVEALGVKIKKWLPSLLNNLSNNLKLTITEMEEKVQHEEDKVDLDEGEVNFDFWECGYYANLSIGKIIQEFKSAELDNIEQITQQLVRLILHQHQWLRISSSKTIGLIFSFIDPTNFTYIGKNKKFEMLEAEGCLYEIGLKTSLQLQGKLVGTELATQIVKNLFFLGKCMYFNKTCDKMQPNSGLVEEAKEENNTTNDTTKESTTLLHLIKKLCYFARTAKTTKETTILRSNIFKLFAAYISFIPTISIQFYITPIFSTLYRASVENLAKGPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX62</accession>
    <name>A0AAD5TX62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Regulator of ime2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RIM11_1</name>
        <name evidence="11" type="ORF">HK099_001029</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001268">
        <property type="protein sequence ID" value="KAJ3204754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX62"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000055">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000009">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="67"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3204754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="421" mass="47063" checksum="5FC8986213F5D277" modified="2024-05-29" version="1">MSSKPKRNQTIPAAMDANSKTSTTTSNQNNSSHVINGIKIGSEPDSSKVVSVQANAGKSGEPVELSYTNYKVIGNGSFGVVFQAKLIENGEYAAIKKVLQDKRFKNRELQIMRLTEHPNIVALKAFFYSNGDKKDEVFLNLVLDFVPETIYRASRHYSKIKQTMPMLCIKLYMYQLFRSLAYIHTLGICHRDIKPQNLLLDQNSGILKLCDFGSAKVLIAGEPNVSYICSRYYRAPELIFGSTTYGVTIDVWSTGCVIAELMLGQPIFPGESGVDQLVEIIKVLGTPTQDQIRSMNPNYIEYKFPQIKPSPWSKVFRSKTYTPESLSLIGKLLEYTPTNRLTAVEAMAHEFFDELRLPDTKQPNGNDLPELFNFTALELSVQPELNKVLVPPHAQAALRQRGIDLDSFQPISIPQPTGLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXK2</accession>
    <name>A0AAD5TXK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000171</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001023">
        <property type="protein sequence ID" value="KAJ3207909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXK2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03399">
        <property type="entry name" value="SPFH_flotillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806:SF31">
        <property type="entry name" value="FLOTILLIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="FLOTILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="6">
        <location>
            <begin position="28"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3207909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="434" mass="48080" checksum="20CF9A742C145C78" modified="2024-05-29" version="1">MRYLIAKADEYLVLTGFNIADIVIVKKALVWPFQKCNRFAITPVNYTLSLQAMTAEKLEFTLPAVFTIGPLDEPEALNKYAHLLAGSDVKGESIQDLVRGVIEGETRVIAAGMTMEEIFKERKFFKEHVIKSVQAELSQFGLFIYNANVKQLTDTAGSEYFQYLRLKSHEGAVNQAKVEVAEAKYRGEVGEKKHLGLTRQENARIESQTVIFENERKKEVLEADAKLRTFEEGYHKNVEIAKIEAKKAAELRNAELQIEVEVKKALVEQERLRVVDLAKTKVTAEATIAEADAQYYKQKKEADAKLYQEMKTAEGLKAIFDVQAKGIENLNSAFGGNSDATLKYLMLEKGLYVDLANANAKAVQGLNPKITVWNTGSNGNEGDSTKPIRDIFQSLPPLLTTINEQTGVAPPSWLAKLNNAAPGSALNSSNTAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXM9</accession>
    <name>A0AAD5TXM9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ciliary microtubule inner protein 2A-C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002468</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CIMIP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001810">
        <property type="protein sequence ID" value="KAJ3200937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXM9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018902">
        <property type="entry name" value="CMI2A-C-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22146">
        <property type="entry name" value="CAT EYE SYNDROME CRITICAL REGION PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22146:SF8">
        <property type="entry name" value="PROTEIN FAM166B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10629">
        <property type="entry name" value="CMI2B-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ciliary microtubule inner protein 2A-C-like" evidence="7">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Ciliary microtubule inner protein 2A-C-like" evidence="7">
        <location>
            <begin position="147"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="197"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3200937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="401" mass="45302" checksum="ECDFC0587DDD97E1" modified="2024-05-29" version="1" fragment="single">MKFSEETACIAVPCYAGFVPSLRYQFGATYGNATRQILETDPSLHQGKLQTKAQNLREFHQLKKNLNSNGGENSSYVNEDFKPKIGLLKRESNSNTNTVKFELEEFKPPQKNKLNRNFNEKKEEDNYVWKLKNKYHTGDDRFSFPPVPGYTGFIPRSKEHFGQPYVETTNESLIDFQNMLRSRKKLPPQVEEILKTRKEKSEKEALAKAATQAEKATQGNKNISSSPSTQKPTYCYSAQSSPIDDVGPYKSARGSKNQTFISGYTGFVPRLQKHFGEPYPESVRHAIEEFTDKKPDWNPYFTSNDGTKVVSSKDKVKVDRAVETRPIPGCTVFIPGSKYGFATTFGKTSEIAYEAFNHREPNGKMPSGAPNSCEAVNRGFPFKDLKKDKPIAGYRGHIPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXZ7</accession>
    <name>A0AAD5TXZ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000909">
        <property type="protein sequence ID" value="KAJ3210059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXZ7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038752">
        <property type="entry name" value="IQCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14465">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14465:SF0">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="570" mass="65116" checksum="3BAB60774FEF0557" modified="2024-05-29" version="1">MSKEKKKRSLPFNKQQSDVSLYKNKNSSDLFSSSKNVGGHRASMPTSLLQSLVSPSQTDLVVIPSLSLDSQILSKVNGLSYYDERLLFNILCLRYNSNRVFYFTSTPLHLDLIDYYCNLINTAHNNLSQFKNRFFNISVNDSSSATCLSNKILFRPQILKSLKNQLNPNKNLSLEVFRGTFYEEKIAKTLQLKLNSCKGRDVIWGTKANSRTIFRHLSIPHPDGTYEAEFDLNRLFERILCILEKNSTSTRGVIKLDESFAGKGNVIIELKETQKVLNSSKKNNQTRRLALKQLKLAYKNSIKDCDGFTDNVKRLGAIFELFNETKHSNNSGKFQTSPSVQVLIRDGKVEVLSTHEQILNGHTYIGCSFPCLQIYREVLETAGEKVGKFLMEKGISDYFSVDFMCDPPLNDNEGWDIKALEINLRMTGTTNPFLLSAHLIQHSLEINNFNTVSNTDFDLKNLIKENFCYISVEQNYNENFKHLTIKDLTEIFKVNSRFGWNPETKKGCILFKFGGISELGCFGLTCISSNIEDCKEIFTLALKFVEFEAIRIKNIFFNQGLSLEKEIFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY35</accession>
    <name>A0AAD5TY35_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000805">
        <property type="protein sequence ID" value="KAJ3211953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY35"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052050">
        <property type="entry name" value="SecEffector_AnkRepeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46586:SF3">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="27704" checksum="B46C0DE88E2E48DA" modified="2024-05-29" version="1">MKFVNLNPDISTKIFLLVDSLELIVAFKKYLYFDYAFKSCAKKKGRKNMKFYVREDNLIFLSDAGITSVVSNHVKQKENKRYQVDESDESDESDESDDLDFNRYDSQNFPITFLEIAIMKQNFKALKFIFTYDDNIQHLAANNGNLEAVKFIESFSNNSYKATKAINKAARNGHIEVIKYLHNKGYSGTAKAIFYAKKNNQKEILEYFEHSSKTEYEKYKNISVKTKTPPTPCIYSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYB2</accession>
    <name>A0AAD5TYB2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008005</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000835">
        <property type="protein sequence ID" value="KAJ3211426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYB2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="92"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3211426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="221" mass="26851" checksum="896C3F429BF24E0B" modified="2024-05-29" version="1">MTPAEGPDADRSQRKRYSASPDRRDKRSISPRYRVKQESRDYRRSRSPDRGFNSYRPRRYSRSPPPRRFSPGRPTRGFPRERPSEEQLKTATNIFIGNLPYKLRERDIIELADRYGRVAKCNVPLDRYTGDNKGFAFIEFEDRKDAEDFFAAMSTHEIGKQRLRVDWDVGRESKTAMQQKSMDRGFDRRDDRRYDERRDDRRYDDRRDDRRDDDFDRRRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYG2</accession>
    <name>A0AAD5TYG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000525">
        <property type="protein sequence ID" value="KAJ3215718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYG2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="1">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="15010" checksum="7ED5F6D4D2D40520" modified="2024-05-29" version="1">MNMGVDANEFLMAKNACQRLTVSHLKNILRSLNLRVVGKKADLQARLFEAINSWQINTLENQKLKLAFIDQLKTMNIIPSNSTTINSTVKNTLIQNNFNTPVKAVESVEKVEFNTLPGVDVVLNLCPPKLIDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZL1</accession>
    <name>A0AAD5TZL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cysteine proteinase 1, mitochondrial</fullName>
            <ecNumber evidence="2">3.4.22.40</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Bleomycin hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Homocysteine-thiolactonase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Leucine aminopeptidase 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Y3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_004946</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.</text>
            <dbReference type="EC" id="3.4.22.40"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.40" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000366">
        <property type="protein sequence ID" value="KAJ3218763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZL1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070005">
        <property type="term" value="F:cysteine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043418">
        <property type="term" value="P:homocysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004134">
        <property type="entry name" value="Peptidase_C1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10363">
        <property type="entry name" value="BLEOMYCIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10363:SF2">
        <property type="entry name" value="BLEOMYCIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03051">
        <property type="entry name" value="Peptidase_C1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005700">
        <property type="entry name" value="PepC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <feature type="active site" evidence="13">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR005700-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3218763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="455" mass="52493" checksum="0A34534DDC6FCA6B" modified="2024-05-29" version="1" fragment="single">MFSKLFKRSKKPVKGSYSTTHVRANEKLPSYQSSVFALSNSEESVTLSNIDEFISDYEKHQKNVLAQTVLTHASMTDVLLNNQVKMNNQEEFELKISTEGNITNQKSSGRCWIFSTLSAMRRGVMEKYHLEEFELSQSFVFFYDKVEKSNYFLETIINITPTEVDDDSRLLQSLFSDPVADGGEWSMVVELVEKYGIVPKSAYPESHNSENTAEMNWLLTRKLREYAIHLRKMILIEKKSIDEVRKQKLQYLNVIYKILCTCLGSPPKEFDWKFRCKNGEFHSYENLTPQSFYKENVSTSFGSSVVETVLLANDPRFPYYKPLVLEHKGNVYGKKLIQVNVPIEVLKEVSILTLKNDQPVQFECDVGMFFKSGIMDLSIINYEAAFDVNVHNISKADRVKFKESKVFKTFFLLTLILQPTHDMLLTGCHFDAKGNPLRWRVQNSWGVSGRSDGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZS4</accession>
    <name>A0AAD5TZS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005825</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000472">
        <property type="protein sequence ID" value="KAJ3216559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001354">
        <property type="entry name" value="ATP-binding cassette (ABC) transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="805"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="156"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="499"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="881"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1113"/>
            <end position="1357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3216559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1385" mass="155955" checksum="D7379600B9FA9D64" modified="2024-05-29" version="1">MISVLNLTSIPAIFSLLLELMDIYPSTVDSHQEIIFSTLQVGILTLQLLLGIKVISKINEVDTTLYENFVKCCKKNNLQLSREKTASVISRTFFFWFTPMIKLGYEKALSMNDLWDLDIDDTTEVIRKKFLDLDANFSLLKRIFLLSKKLLVFQCAFSLCSACLAFAGPFFLNRIVSIIGNPTSDVVSLSYILGLFVCTLTRGILDGQTYFTGRRIGLRIRSILISEVALKCLKKPLGSNEDEKDDDGFYIEEENDTAQKPKRNGNAINLISVDAQKILEVSCYLCYVLSNPLQIIISVVALIYVLGASAIAGIFILFICAPVGGLMGKRIARSQENLIRATDCRIKKTNELLQSIKIVKFFNWEKSFLNTLLIIRKTELKFLKSYLTKIVYFRIIWWTMPILCSLTTFCVYTKVFQNELTATIAFTGLALFNTLKFPLFSFPDIIVKILDSYVSFKRIDKFLNSKEVPSAIRQKNFAKDDSNFEVNVSSSTLTEEEHISLIEASYKWERSTDACLAEHAFKLEDLNLRFPRNKLSVICGATGSGKTSLLQALLGEMKIYHGSHITSIADDSVAYVSQQAWLQQLTIRENICFNNDYDSKWYKSVVYACGLKSDFDSMPSGDKTEVGEKGMNLSGGQKQRIALARAVYSKKNLILMDDPLSAVDAPTARHIFNECILKLLKNNTCILVTHAIQLCVPHSEYLVLMENGKTIIHGETKDVLCEVQHYFELTPSELTICAKANNFTPAKHSNQLEGDSKSGVGLIASKILNNSALELESCESEVRITNEEDRAVGSYVTYGKAGGGILWLIALVVGFIFAQTMIFVSDYWLKLWASAYDKLNYQSFLTSSAKLFTVPTSPNVLFNVIYDGNFTPQEYNVEVDIGGLEIFSLFMRLVVLYRGSLEASIALHQTLLERVLKTPMRFFDITPIGRILNRFSRDIQSIDQEIIGVGGDFLINLVKMIFVKELNLNFRWYIRTSRELKRLDSVSRSPIFSHFSQMISGVCTIRAFKSQEVFLKENNARIDDNHKAFFYLWVSNRWLNLRIDAIGAIITLSSCTAIFIAIKSGHVDAGLVGLSLTYTLSFSDALLWIVRFNALLEMSLNSVERINEYLLLEQEPDVINDLVPHLVCKNNNAGIQFSFVSGEKIGIVGRTGAGKSSFSLALFRFVEATSGNIFIDGVDIASLPLSQLRSSLTIIPQDPVLFSGTIRFNLDPFNLYTDLEIYTAMKRSHIMDSSEEFKSDSTRKSIISLESTVLEGGTNYSQGQRQLLCLARALLKKSKIIILDEATASVDHETDAKIQRTIRECFYNCTILCIAHRLRTIIDYDRCLVLDFGKIVEYGKPLDLMVGSKTKDDRRIGPKGNFLKMCQESGEMDLLLEYAKKGNAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U015</accession>
    <name>A0AAD5U015_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA ligase kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000359">
        <property type="protein sequence ID" value="KAJ3218939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U015"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015966">
        <property type="entry name" value="tRNA_lig_kin_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004:SF1">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08303">
        <property type="entry name" value="tRNA_lig_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA ligase kinase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="190" mass="21910" checksum="D2E409E8DA826366" modified="2024-05-29" version="1">MISINKDTKVLILPCAVIASGKTSLAKLLKNNFNIGHIQSDDIKAKRPAPIFVEKVMECFSTEGKNIVFADRNNHLLQHRLALSTAFKKKYPDGKILGLNWEYDQYSRDQMKKICCERVLMRGNEHQTLTPEKTPDFERIIQMFLKQRVPLNNILNSEDSYVDVVLNLNIDNQIQQNFDLVCKALGWKYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0F5</accession>
    <name>A0AAD5U0F5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nuclear pore complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NUP84</name>
        <name evidence="9" type="ORF">HK099_004260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
            <location evidence="7">Nuclear pore complex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the nucleoporin Nup84/Nup107 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000298">
        <property type="protein sequence ID" value="KAJ3220487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0F5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007252">
        <property type="entry name" value="Nup84/Nup107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003:SF2">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003">
        <property type="entry name" value="NUP107-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04121">
        <property type="entry name" value="Nup84_Nup100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="5 7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3220487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="800" mass="94491" checksum="75962241853DB512" modified="2024-05-29" version="1">MINQQKDFSDEDEMMVEKDQYNQNDRNVLKTREELYGDLDILLEFGRIFKNYDSGVDLFDEHYGLLHQIQDAIEVKLNNAESKYDKEFYNLELNTWDLVSRLFSLRSSMIENKPNFENKFLSDHGLAMKLFMENDHIKECYIVKEWLEHTAKEFEPVSRRGYLTFTLKEIRAEKENVISQIDPDATTRQNKNLAVGDEELAKALNKTLYEYVRRGQVDNAIDLCVQCEQPWKAATFRDGDHEDDNAVAMGNSNKELWKYCCALYAKNSNDIYEKALYSFFAGEVEHASNVCNTWEDLVWIKFNALIEYEYDQFLEKEKIYARNGDELNLPSEWTKEIAKKPVEIFSDLASSEKFSVEANNPFRIIQAFLIIDDYNALLHNLKVHLEKAQIKSENAKEIPRLHAILRFVVHLIIISRSVFNDSTNDGSFEQVSVLRSSENYLIKHYLDMIKLADIQENTFFEYLPFYCKFLPADQREVWFSQFLYTLSESRKENISKEVKEELLSLAKDAKMNSLTILKGFFELKYRNFFLQSLPSNSTQILIGKFSKELDNVDLDYIDCLEYLSFSENCFDELLYYSNRLCRRFLLFGRLNAFKTLLSKALPQKFLKWIESKNNQQEKNFENITDLNEYLAYQGLFKGFKLYFKWEECLKQEPEKYNKESYNLWEEEFKLLTQNTEQTFSLVCQMWADVEEKSDKHYSEEGALKREEETELLKEIYSPEIFFFRHNVLYSSSHVIPENLERSLKLVEEVSENVAFTLYFKLSKKLEKFLSLVRKSSLKMLAALEGGSLKQIDMCWGRKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0K4</accession>
    <name>A0AAD5U0K4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA cross-link repair 1A protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DCLRE1A</name>
        <name evidence="7" type="ORF">HK099_004587</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000329">
        <property type="protein sequence ID" value="KAJ3219731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0K4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16273">
        <property type="entry name" value="SNM1A-1C-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="424"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3219731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="511" mass="58816" checksum="F7C4FCB545F8B893" modified="2024-05-29" version="1" fragment="single">MSNLINDSKYSQCPICFLNINPNEIQNHANSCLDNLFLQSKKHYSIVNKQSSIKNFFVNDDFKNCDVSKSKKDKLINLKQKELFESSIMVKDSSKKTENTLSDCSEKLNFSLCLEKNLDILNTENIQSEIIHKEKIVLDDDVESISSAFVKVEEKLKKSSNQSETTKSFEGLKSCTSLDGSSVITKFENELIRNNNADSLDEIVINDKVITLTPSYNASYKKTDETSAEEKIEDVQPSNKRKPIPLYKFMPDTNFTVDCFNYGKILNCSGYFLTHFHSDHYGGISSRFESGQIYCSSITANLLISSLRVKPEFITRVPMNQVTMIEDCLVTFIDANHCPGAVLILFETKNKKKYLHCGDFRVSQKQMKFLKSIHFDKIYLDTTYFNADYKFPNQPLILSLIEELIKKVENGENLKGIFSKDESNHSADVHLCQMNDLNKDFVQKYLKTFSSSEYEQILTFRPTGWTFRPKKRKNTSKDLQSKEFELNDITPKFDFISLENKIIPFINFNIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U127</accession>
    <name>A0AAD5U127_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spermatogenesis-associated protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPATA4_1</name>
        <name evidence="2" type="ORF">HK099_004145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000287">
        <property type="protein sequence ID" value="KAJ3220608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U127"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051493">
        <property type="term" value="P:regulation of cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010441">
        <property type="entry name" value="CH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052111">
        <property type="entry name" value="Spermatogenesis_Ciliary_MAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509:SF8">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06294">
        <property type="entry name" value="CH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="942" mass="106509" checksum="5A3A84D71174F74A" modified="2024-05-29" version="1">MSLSRILLKWIQSLDLSYAIKNCKRDFANGFLIAQIISKYRSDLVGMHSFDTGSGPAARRANWDLLTKIFIKLELNISEKLTKDVSSCSPTAAPKILEIIYQKFEVEEKNALKKGEVDQSNHTENNVIDFSNSNVNANNLGSKANSHQSLIKKFGCNYTFNSSNAVLEEFQNFEENFSQRISVVNPNFNNKSQKNETENLTCNTNEIITNKNSVVFTYLKSGVLMPVSSASEQRELIQNNEDSTSGKVAIMKVVVNLIFQCLDVPNNWFGRLSYQMFSLRDIISRRFSEDKVIDDELNSIKCLLEEKDAIIFSTLKSSLPSDISIYLDTFLGLIVSSDINTLVFKVSKLLISHISQRLHHLNFISPIKQLDPFQRLLNTKEIQNFFFYFLLQPKSEKFWHMVEIVHNFAENISAIEGYEVPEGERISGLLTIKSYIKSLAKQHDSRIAITSFNSCFISFLFLFIHFENPKKLLKNSQLSTLYLSESLTVLNSSKPYFLNANQSSLKNDIVLDCTFALHILAHLAHCGVSSIWSVIDDEGGILKKIIVTKISQAVSSVVVTDALLNGSVRLIASILELKGSDNNNMIGQLLEITAIYLNILTDEPLMTALYLIGSVLERYPKLSSVFVKGIMSLNSKNRLNLMQTQTNSQEFTINWGINSILSSVISNYGCKNKAWWVFGIGFGLVNAVTANKCKLSACHFEILKPIAILSMLSLNDSNVKIRMKNKLSWKEVFNKLCELVLISLTQADCVKSAVSCLNVFARFGVFDDNENMTSLLTAILFVFKNSQGPHSRNQVFKLISAWIEGDDNLFNREKTNCNNPEGGQQLACAAENEIIEKACQEPVKLIESVDFDGVKSKNSSSENFTEENFKGLKDESILNKTDYNNSIEELEPYFNLENLNNSDLVKIEMKIFKVQFFKKLKLFEEIFPNTFENLPELNNLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U170</accession>
    <name>A0AAD5U170_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004902</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000361">
        <property type="protein sequence ID" value="KAJ3218878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U170"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011:SF28">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="316"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="421"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="672" mass="79004" checksum="9E71993492FB7C34" modified="2024-05-29" version="1">MVQIIKRNDGEYVVNNFNATYLEENHCLECSINKMEILKIKQVKKSKKEAEEERKIHNTKIRELMKETNKLFVTCSKPCEHFKKFKTTKGTKFQQKLDEEKKHEEFKKIFDEKFNQKHFQQNNFFKKEVEHSVNIVYKKTNNLLPVLNDRILGIGNYKNGSRKTRKQNENMLDKENNIFENIIQYNMKLDNNLKKHAVKLNKKFQCKKKKAPDNEEFDLMDLEEETKSNNNHTNHNFTSRDSETNVALSSDKIQNSSQNIVNNNKKDENEVLINILKKPSNLRVNSDIKKAFSCLRNLKAFKKVSQKVLLQLIEDDSLNLETYNKNQLVFSQGDEGSNWFVVLVGEMIIIINGVTVGNIVPGFGFGELALIQSHGVRAATIMSSTSSVLLRIEKSDYNRILRYEHKRDRLEKVTMLRKLPVFSNLSELDIHSFSDCISIKSFKKGQIILKENDTLDEFCFIKKGTLSVWKNFDLNCLQEEEDIGIIDTCSNKRKHLLRKDEIKFNINGKFSRKIISNKKPIECEIDLKNEVVNNAVINETDANVIKIFIARLSEGEYFNEKIVHLHPNKIIWERSQVEIKCETDVEVGVVQRYNAWSKIPKEIPNILSRKDYTKNVLKGLYLDQIERKKWKMYKKKYLELIFREKFKDPNITLKMWEKNRTMKDNLSYRNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1H5</accession>
    <name>A0AAD5U1H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U three protein 23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">UTP23</name>
        <name evidence="10" type="ORF">HK099_006183</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in rRNA-processing and ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UTP23/FCF1 family. UTP23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000518">
        <property type="protein sequence ID" value="KAJ3215825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1H5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000006">
        <property type="entry name" value="rRNA-processing protein UTP23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057776">
        <property type="entry name" value="UTP23_sensor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24779">
        <property type="entry name" value="UTP23_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP23 sensor motif region" evidence="9">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00076388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="289" mass="32880" checksum="D5AD439424CD2D12" modified="2024-05-29" version="1">MRVKRQKQQKKIMAVYTNSFQFREPFQVLVDGTFLNAANLMNSNLEESIPRIFAAQVKLMTTNCVHVELKTLGYHYKVPASIAASMEKRKCNHYPPKSPAECFQGILGEENKFRYCVATQDKNLRSILRKIPGTPLIYINKSVMILEPTSPATTKRAEELELEKSKPLSHEKILVLKKAELQQKESESNLAFNNKKKKPAAPNPLSCKKKKPKIVPKLVAKLEAAPLIKESDTVSKVKSQDLEKTLTSLKRKKDVNLSEIDESINDVMSTSIKKKRKRRKSNKKLQSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1H6</accession>
    <name>A0AAD5U1H6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000259">
        <property type="protein sequence ID" value="KAJ3220985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1H6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47725">
        <property type="entry name" value="OS03G0364000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47725:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="127" mass="14569" checksum="CF4433AFF897B91F" modified="2024-05-29" version="1">MSFFVRVKRHKQTFFIDELTSSDTILTLKERLEPLINVKPENQRILKESTPSDKSNLHEKNPQTIVNANSATDKTYINIDENSVLDQLGIQNDSVLYLVYKLEANEWESVAVPNFEELDEKGKSVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U247</accession>
    <name>A0AAD5U247_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mannosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ALG12</name>
        <name evidence="13" type="ORF">HK099_005040</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29535"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19518"/>
            <dbReference type="Rhea" id="RHEA-COMP:19519"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132517"/>
            <dbReference type="ChEBI" id="CHEBI:132519"/>
            <dbReference type="EC" id="2.4.1.260"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:29536"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000379">
        <property type="protein sequence ID" value="KAJ3218467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U247"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052917">
        <property type="term" value="F:dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF1">
        <property type="entry name" value="DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="235"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3218467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="465" mass="54995" checksum="208EE1242B587EFE" modified="2024-05-29" version="1">MHRLIVGFSLNFMNSKIKEIYGKDASELFSLFNLTQFHLAFWSTRTLPNVFALVFTNFSIGYWITFVYEDAKFCNNLKNTLKSKEKSNLTSYSKIKKAESIKRHDSKKLNLKFLTLITVCGVIFRSELVLLLGSIFLSEVFYFKSLNAFKTFKILLEAFFNALFVNVLVDSWFWNQKFFWPELKVVIFNVIENKSHLYGTLPFHSYFTNLLMRIAPLTYPISLLSLIAIKETRRFLVPFFCFVFIYSFLPHKEWRFVMYAIPMFNFTAAVFIAKLTTLKDDDEKFIKNLKLTTKFFIRLLSFILLALSISGSFISRLNYPGGNSLDKFNNIIKTDIKNGFQSEVKIHIDSFNAQTGVSLFLEEEKIIQYSKNEKLKFNKNFVENNFTHLLIEKDDKFDTNFKDFKLLEKVYGLESIRKKSIKTYWKDLKSLFIEKDQRMQKLLPFTVEIRAKSYILERRDFRQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2B0</accession>
    <name>A0AAD5U2B0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glutamine--fructose-6-phosphate transaminase (isomerizing)</fullName>
            <ecNumber evidence="4">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GFA1_3</name>
        <name evidence="14" type="ORF">HK099_006566</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000577">
        <property type="protein sequence ID" value="KAJ3215000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2B0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00714">
        <property type="entry name" value="GFAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000001">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047084">
        <property type="entry name" value="GFAT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001484">
        <property type="entry name" value="PRK00331.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="12">
        <location>
            <begin position="2"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="13">
        <location>
            <begin position="364"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="13">
        <location>
            <begin position="536"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3215000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1060" mass="117901" checksum="268E2BCD9CA55C0D" modified="2024-05-29" version="1">MCGIFGYLNFLVEKDRKEILNYLLTGLSRLEYRGYDSAGIAIDGDTEGCDALLFKEVGKVAALRKKIFATEGLDQGKTFLAHTGMAHTRWATHGQPSVINCHPHRSDPKNEFLVVHNGIITNYKELRLVLEKKGYKFESDTDTECIAKLAKYIFDSQKGGSQLTFTSLTKAVIKELEGAFAILLKSSHYPHEIVAARKGSPLLIGVKTQKKLKVDFVDVEFGPGPETDKTELEGGADTSGKMKRTQSRAFLTEDGLPQAIEYFLASDPSAIVEHTKRVMYLEDDDIAHISAGELHIHRVKPGDGLTSIRTIQTLEMEIAEIMKGSFDHFMQKEIFEQPESIVNTMRGRVNFDTGKVTLGGLKAYLSTIRRCRRLVFIACGTSYHSCVATRSIFEELTEIPICLELASDFLDRKSPIFRDDVCIFVSQSGETADTILALRYSLERGALCLGVTNTVGSTISRETHCGVHINAGPEIGVASTKAYTSQYLALLLIALQLSEDRISLKERHQEILAELLELPTKIKETLSIDSELRDLAKNELLKEKSLLIMGRGYQNATCLEGALKIKEISYMHSEGILAGELKHGPLALIDENMPVILIMTKDSLYPKVQSALEQVSARKGKPIIICNPGDANINKNFRTIKVPQTADCLQGILTVIPLQLLSYHLAVLHGVDVDFPRGAANSNWDNHKFIADAMIAMAETENPKFVIGAGDNFYAGGKYLLSGEGVKSTEDGRWKDVWSDIYLKGKLTNVPWYVVAGNHDWMGEVDAQVDYHKVNPLWNLPSFFHDMTVKLPTNYCKNKGLSCTDEAAFIFIDTDFLYYGYNWNIEAALMWSEMKEHGWTSEKTGDEQLAWIESKFLEHQNKAHIIVIGHHQLGGCKTSRRMVELDALIQKYQATSYMYGHLHALAESRIEGSITSYILIGASGKDYDPDGCSGGNAKINFDLQNTYGFVRAFIDNTGFKAEFFGGEGRGEVGKIPTICPEHKPKKIAGLCYEQCASDQTQVGPCCLKSSFPWVNSCSVGVAPNICPENYELYLGLCYFNGKARLLYSTEYVLPRNGTNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2D0</accession>
    <name>A0AAD5U2D0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000569">
        <property type="protein sequence ID" value="KAJ3215095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2D0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="125" mass="13928" checksum="4AB1B7ECEBEC743D" modified="2024-05-29" version="1" fragment="single">LKKKSENFNKPKLNADSSTIEKSNGSNLFSVNSATEIQDSATKKAKDSPSNKEQSNSIAEAVRMAKEADSSQPTFLYEHCVKPFVHVMSGLGNFSKNTKFSIKKWIKSKSGHQIDERSGIRHIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3E6</accession>
    <name>A0AAD5U3E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MDH1</name>
        <name evidence="15" type="ORF">HK099_004671</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="JADGJW010000337">
        <property type="protein sequence ID" value="KAJ3219512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3E6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="127"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="97"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3219512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="293" mass="30992" checksum="4331E1361BE1975D" modified="2024-05-29" version="1">MKLNPHVTKLALFDIVNTPGVAADLSHINTPAKVTGHKGADQLGDALTGADIVIIPAGVPRKPGMTRDDLFNTNANIVKTLAEGAAKHSPKAFVCVIANPVNSTVPIVAEVFKKHNVFDPKRLFGVTTLDVVRASTFVTDIKGGDPARNKVTVVGGHSGVTILPLLSQTEHKFTQEELEALTKRIQFGGDEVVKAKDGLGSATLSMAQAGARFANALIKACKGDKTVVEPTYVKSDVVPGLEYFASNVELSEEGVGKIHPLGTLSQYEQKLLEAAIPELKSNIAKGVNFVKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3G6</accession>
    <name>A0AAD5U3G6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001439</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HscB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000140">
        <property type="protein sequence ID" value="KAJ3223188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="entry name" value="HscB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021:SF15">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="HSC20 (HSCB), C-terminal oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1172"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="10">
        <location>
            <begin position="1270"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="324"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="795"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="844"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="127"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="868"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1438" mass="161383" checksum="63F25640B38C0DC2" modified="2024-05-29" version="1">MIKGDDGHKNSTKSTLEMNLVGRQNLSFPSLRRKSSFDKVASLVSKTKRLSMQLANLKEIEDEFFLNGKSKRNFGSQVEKEEVLDYSEFNNILEIMKNDLDTAVKMIKRHQMANLCHQSKLLYEVLLSEINSLKKEQQQDLKNIRKECQEMLDEAILGFGEKLIEDNEFKALELKERLSEQEVEIDDRFESQLKILTRNSEELERYRFTAARYYILLKKHGILEDQKEWTENGEKLRTANLIEVFQLKINDLDKQLGDLRGSMGVIEEKFEKQVNLSPVLAQQLNMLNSNIVDLGNGKSNSPGLSNNAVDTSILISIIKRALENQQKSSKPGSRTGSRPGSSTYSRPPSSLNKSLKAAKTQKKSISFDANFKFSSNVQASSASLSRFSINSDTESTASLNKKYTNTKSNSRRNTSTQLNDIQISVSEESDYKIPVSSKSRVSFDHSSETKSANTKLAKFKLTVENIINNKKKPESGTKICSLKTPENNAAPKFTKPYEFLSANNLNLAENRLNGKGKNLEFNMIRLNSDTLDPKDSTYLLDSFSGQSSRKGSAVPSSRYGFPNSSFSGRGSFYPQINNSNRSINENVSVSFLSPNSNSMFQEVRRKSKAIHESADHSERNQTRLMIKKYADDISRAKLKGEKELNDLLEEKKILKALWKLKIHTLKKNNSKTNIKQLIKKQANLIKLAVKLTSSVTVEKETQCELGGLCYRDTLPKPKAPIKLKEPIYEAAKTEEEIAVANSLLGGRNTNSLAFMLQGFSISSASPSLNGLDSTSSSHSSMSSFSVTVSREPSIFNLNTKDRRSLPTRPPLHQKAKPSNIFGDKQFSSSTINLSALDQALNEILKEPKSPSIRSRSKTEQPKTLSAMPLQNSSSSRSTGNLFRSSSAMNLTEGIKKSKKKSSTPAVAFNLESSELSDSKKSQLGLDNIIIKKNGDIEEFIFSVPTIPPPTSPNATSLNSPNMLVEDASDASDAVTKNFLKAPLQKNHFDNTKVSYEELCFFVPSFSSSGQNDASVTSASANPCNQSSFSKNESLLESFKVVDIESQEKIENSLEKNSSSISASSVNNSYMDTEGVFSVSENCTVSVPQIKTGRNVLINFEVMVSNYDEQTTNVVADNSGFFEENLFEDYVNSRVHESTPLLRRASVILIIEEETFVGTGVLFLPKAFYNGGILFSIIILFVTGFLALHCMNLIVDISRELGGMSYGDIGGKIYGRRMRSIVLFSIALAQSVSCWKCGQSVASKPKNGHATFEPFCVKEDCNVIQPVNKNLNYFELLNANDKTGFVNFDLNLIKLKKNFLFCQKLLHPDVFSQRSEDEKKLSEEQSSVYNKAYQVLKNPLYRAEYLLQLKNININESELQNNVTFLNKIMEIREEVEDCKSVSELESLQKENDERYELTVKRLAKEFKDLNFEQAKHSTMELKYWAMIRNAINEKFNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3J1</accession>
    <name>A0AAD5U3J1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CREG-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000149">
        <property type="protein sequence ID" value="KAJ3222983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3J1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273:SF1">
        <property type="entry name" value="ADL397C-AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042027911" description="CREG-like beta-barrel domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="CREG-like beta-barrel" evidence="2">
        <location>
            <begin position="23"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="220" mass="25002" checksum="97B0FCCDD8FE5CE7" modified="2024-05-29" version="1">MKVISANLGIISLFSTVFCISSKEQAAIARVLVSNDTEIASLATIQRAYSWDESDGFPFSSPEMFVDDNCLPNPKGDIYFFLIDWGVHAKNIYANPKISMSFRDLTLYDESKASEQDKKKFIKNGWADTKRLTLEGTAKKVDPSSTEFKLAKECYIKKYPVIKNWYSPDEKTGHGQTDFVPFKLEVKYVRYIGGFGIAGWIPLEYYQSKDDSDKFIDDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3M4</accession>
    <name>A0AAD5U3M4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004099</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000280">
        <property type="protein sequence ID" value="KAJ3220698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3M4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19821">
        <property type="entry name" value="Bbox1_BBX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19756">
        <property type="entry name" value="Bbox2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049808">
        <property type="entry name" value="CONSTANS-like_Bbox1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047153">
        <property type="entry name" value="TRIM45/56/19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462">
        <property type="entry name" value="BONUS, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462:SF296">
        <property type="entry name" value="MEIOTIC P26, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="4">
        <location>
            <begin position="191"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="4">
        <location>
            <begin position="248"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="533" mass="60665" checksum="515579A8DF4D8441" modified="2024-05-29" version="1">MSDRNGTKTPLNHSAPEYGYLEYALQLSLHSSTARISTCHSVSNPHLQVQFDRKCKDVMQQNCWLDASILTGVNTEEEVIRRGFQFTPGQVHGLKIPIGSLRRNLRGMKGGKVVRKLLFCKIGLGRSFVCDEASVETKPLPDGYDSFYIQEGGLKEDPEYYQEYFVKNSQQILPLYLVQYEFDNSKEKKSRELPNCDNCEEEVLATVYCAADKAHLCNKCDTKLHEPKVASRHVRTPIGKGAEIFGHCRHHQEEWIKYYCSQCHIPVCVVCKMVGNHSNGDCAKHQLVSVTDAYNVVLQEAQAVDPVLQGRRTEITNQISAVNSRAKAVEKMGHLVQTQIDEIYRRATEDLRILIQRKMDVLLGDQIELKRQIMEYDRLEDFVKYQQAGDPTQFLFSWSKQQKVRQELHDFKFFRDEIDVNLDIKVTGGVVVSIDHDPIPNSQTNNNYSIQNSTSQSCPSGAIKTITPTMQNMNQQIQISNTSQGLIQKNAVSVNNIGLGIPRRSSERRVQRRTSDFFSETLGAFDQFNLDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3R6</accession>
    <name>A0AAD5U3R6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000128">
        <property type="protein sequence ID" value="KAJ3223479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3R6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039891">
        <property type="entry name" value="VWA8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21610">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21610:SF9">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="128" mass="14448" checksum="9778571D81BDC4AB" modified="2024-05-29" version="1" fragment="single">MEAFKKFEHKFEYRISGHSGDGADINFVAEGKYPKNEKEMFEVLHKMNQHAQFCLSGDNTLEATIQAIKNIKKEEADDYFVLVLSDANLAQYNISTKAISDALKSNSEVNSYMIFIGSIKDQADELVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U428</accession>
    <name>A0AAD5U428_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000279">
        <property type="protein sequence ID" value="KAJ3220716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U428"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="84" mass="9534" checksum="E69D180C5083760A" modified="2024-05-29" version="1">MLETILTLSKTRKNEIRLKNSIEEKIELNLKKINYVPKTLSEGFGLIFAPGRDSLYFQGPPQIWAGSIEGHLISLTNAIAREYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U436</accession>
    <name>A0AAD5U436_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box/LRR-repeat protein 15-like leucin rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000397">
        <property type="protein sequence ID" value="KAJ3218072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U436"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="2">
        <location>
            <begin position="111"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="633"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="654"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="675"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="695"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="904" mass="100662" checksum="9E0648C6BC3D60D8" modified="2024-05-29" version="1">MEHSSPAQCTIANPALDNAIISTSCAKYFDKKILYNLIDNIPNHSDQISLSLACRKWSIPCLEAMYHSPPLQNSDSFERMLSLLNTPLPYINYTLLIKELNISSVAADNIYMGDLDFCLAACPNLELFRLENCYHISNILVQSLSQLCKNLLQLELSGCPISDTFIKALTKNCKSLQRLDLSFTNITITSLFTILTNSKNLVSLDICECREADSELNDLLVSEGSKCNSMKYLNLRNSPISDELLIFVSDLCPNLEDLILDSAVLVTDKSLVHIIAKCLRLKSLDLSFCDKITDVTLYKLYEISLIHGSDLKSLYLSAVDFISTDAILKVILCCKNLSLLILDGCVNITGSFIQKEFATFKEDLECTLEKDAIRLLYKHASTLFNTPPVSPKKVNDTKSFRTAGEEGELKVQVSFGNRNSEKKSKIFSPPTTPPRIISKRSSMRMLRSQSLLIGSNTNNTSKIINQEENDYFRHERQEKIREKRKSKTLHQMNSAYRSAPSNATTSSENLDNRFSSCLLTEKNQNDGATSFSMQQTSSYQFVPPQIKNYDTNNSASSNAVSETNAPVVLASGRAARKAQMLLSQQQQQKTEHEGNENSNLNDATSVLETASEDPPQKDSGVIIASGRRRRPQSEIASKSSNLSASSQPFVPSEQIQHPLQRQQQQNNDSAPEWNASTSAPPATTTWGAAPPMWTNPAQMTSASSTWSASIQPVSTFADPWASAPPPQNSSTDPWAAAPSSMQPPPPAQYTQQPMTFSPNHYQNESHSSIIYQSPQHSSVYQQPIIYQSNGFQQQNNFQPVTNSNTNQLRVGASAGWAGEQDQNHVSTTPIFIYSNSNRGRMLLKLRIETKKGGHQTLEVHELDDPNQLSQEFCDFWQMGAFKDPLVRLISVRKSNALRQRGIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U440</accession>
    <name>A0AAD5U440_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U440"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="27421" checksum="8ACD4349E76E4F34" modified="2024-05-29" version="1">MTTIKLKLSSNLSSSNNQAQQSLEIFNQSRKKEKSVQFHTSFLDTKKAYLNKYRPNWLKDTLLHHGFDTENGEKSPHPCFELYLKKNNPPKNSIEEVANKIRSSQEYFFNFYGFDQQRDLDLLKEFNKNDKKIFTAYCSEYGYNGYFWSFCAERMENITNVWHCRECECCFDWNFKHCLQCNKCSEFSKDYYNGLNCDRCFNPGNSTPIKIHSKTSTNVIAVRKKKKNNLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U470</accession>
    <name>A0AAD5U470_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002712</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000192">
        <property type="protein sequence ID" value="KAJ3222097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U470"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF11">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="475"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="400"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="570"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="874"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="582"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="875"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="898" mass="100441" checksum="6F31F5C090041FEE" modified="2024-05-29" version="1">MLNVNAEPFYIQPEANQKARSSSNLNSSLDPIYRQEDHLQLPTSASYQFSNASSAYQTATPNSPAVVAVKKTRGGTIIFVSNCKGNIFGLEQLALQYTASTVVHIGNFGLYDRGTISNIDEDIVKKNLPEGKECLYYQDIEFLITQKKRLSINLYVVPGDLDDPALVEKLKLQPELIPNLHLITTSCCLELEQVKFKFFKFCKFDLINDFDGCKSYLEKLFEESDSSVEKCEVKIFCSSYTAISDADDQLLYKLAYNLQMDYLLQVSSTNFLGYQPILAMDNQDEVYKIFSANATENNGVVSRFLSFYEEQHVKAPPQNFNFKLPLYEEGHVVLNVNTTRVSHIIVNGGLNLAGKFAQQVGRAFNLLKIIDEEVNQISEDNRSPNNKSNGAANNPWKQKFHAHSQENKLTSLNENSEVVPRPRPKNDRNLPSRPVSWSSWDNIAENAIVYQSRPLSGSSWETATDSSGFDSENGITIWVGNLPEVVNETDIRNFFRNIPILRIKMTTNRPDKRPCAFVDVADTDALEAALRLGGERLHGVRLKVEYDPSRLKKEFGFKGRANSYPSLSAVAQGKLPAEQDHQTQQQQQLQQLPRLTKSKSSDWIGLQSQKNHTTETLQQQAINNNWSNFSNNEFNNNMNLDALGKSSSWDSPPRKEVQSFSSGKNWDLPFNNKVNSIIPGMGWEDKSSNNNLNLQNQSQNNHPWITKSKSSLNLSWTTDGSPLKSPIINSTPGFGYGTVSSPSNNSLGLEWNKPSVQQSLRSPTSTSVQSFWNSNDVGNQNLMNNNYNQEKLKQQSKVWKNDKLGVRPGLNIITDFGNKSHDGSPLSAPILGKNTQAYNNPWGNFTNNQTPAITTTPVSSTPTNSGFNVLGSPQLLANTARPPSNNSNNSGDRLSWCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4D7</accession>
    <name>A0AAD5U4D7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SWI SNF, matrix associated, actin dependent regulator of chromatin, sub d, member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SMARCD3</name>
        <name evidence="3" type="ORF">HK099_000585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000114">
        <property type="protein sequence ID" value="KAJ3223865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4D7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10568">
        <property type="entry name" value="SWIB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="2">
        <location>
            <begin position="193"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="391" mass="45535" checksum="F697D886FC547582" modified="2024-05-29" version="1" fragment="single">MNPQQQQQRLQMQQQNSIPMPGLPVPNMQGMQIETFVPESKLFTQLQDFEKRLDQTILRKRLDIQEALSKPMKTQRFLRIFLSNLASDQYVEEGGQEDNNMDADNIKCPSWTLRIEGRLLEPTVGNKKGAVQKQFSHFIKSVYVELQRDAGLYPDGNMIEWHKQPGSADCDGFEIKRKGDTNTPVKIFIQLEHQPEKFKLSAELSRVLDIHTDTKSNCIMALWQYIKLNKLQDPDDRRYINCDDTLKRVFNVQRFLFTQIPELLNMHILPPDPVVLEYIIKVDKEYHIGQYAYDVEVEVDDPMKAKMTGLLNDIPGLNKELSNYDEKIIGIIQAINQCKLKRDFFLSFSNDPCGFIKQWMASQNRDMEIILGDVRIDAEDARNAKFFDQPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4L0</accession>
    <name>A0AAD5U4L0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000096">
        <property type="protein sequence ID" value="KAJ3224331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4L0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004177">
        <property type="entry name" value="DDHD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055555">
        <property type="entry name" value="PA-PLA1_DUF7131"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057826">
        <property type="entry name" value="WWE_C20G8.02"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF10">
        <property type="entry name" value="LD21067P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02862">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23465">
        <property type="entry name" value="DUF7131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23463">
        <property type="entry name" value="WWE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01127">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51043">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDHD" evidence="1">
        <location>
            <begin position="491"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="685" mass="79148" checksum="EEFC756F0EAF199A" modified="2024-05-29" version="1">MQDIKTKAVDEIENTEDLEAKKLENYNLTISDRCITEEPEVPETLWFYCEKPQGDTRNGFPLFLENPKNNSDNFTWCRFSKIDAKKLEDCFQTQNYEKKVLLKDDYLFEADLQLMRMTAVYWIGPYFEIRRSFWFYKPVSTFIPCCKELSEQLEQGFQKLKPWKLSFDEKNLNDDQIKFKLTDLYEKQYCVFESPAGAIIHSELIASKIGRVVIGALMSNENFGGTKTLRGWNQVLEVTGSKNVEFCNDEFDEEVTSFDREINHVIFCVHGIGQNLAKKMDSMDLPVSVDQFRLLFQKSSSIIKTDHPDLNIPELGGVQVLPIQWRQQLNVYERNFKNCEEDSDEENEFLSLEDVTLPGIPSIRSLCNDVMMDLLLYMTSHHKQHMVNHLTMEINRVHTLYMEKNKDFKGKFSIFAHSLGSLLVADILANQENEILDNTNGADNEAAMKDNEIYMVEKPDFNFSENLRAIGRGNAKFFKKFSDSDIKYQKLNFDVNMLFEVGSPLGLFYFLRGNRLKGKRDEHGEDKNPSVVNLKVKAVYNIFHPHDPIAYRLEPTVNKSKSKVLPQRIKHTKGGITSIAVGINDTQNKLFSTIETLKNFGIFNKYNDVEGEAGSCKESKSTNGFENWEREIAILNPNQLRLDFSLTENVTESMNPYLSALLAHNGYWIDQDVCCFILNELYTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4X1</accession>
    <name>A0AAD5U4X1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000092">
        <property type="protein sequence ID" value="KAJ3224471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4X1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="357" mass="40151" checksum="3501F641AE09840E" modified="2024-05-29" version="1">MGVNLRPRLNNVVSTQRISPKSTDSIKKKKTKSKMPLTTKSEVIKPTSSTSTTSASLRSTFQVTTDSSQSTSIPPTLPSNLTTKSSFNVNVTLAVKNKKNKKTNTQKYDNSDSKFRHHFGIHEGNSAPTKNATSAFVSPYPPYSQQNYSGNITVLSNNEINLKKENNRNANINTFNTGYSTFNLPIAKPNEESASDKGTPLINEENFNHFLMKNGLEGENVRFGNFNNDRVCIRNSHISAVDLNSDLKEELRRSYFSQEDGRSSRNFGTLKSSKTDHNESMLNKCRETEFSSGTLRSEDHIPNVPYNQDDVQNFKSKFDVGNYPTNDLENRDNEKLREEQMMRKNTISMILKMSGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U539</accession>
    <name>A0AAD5U539_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transcriptional regulator swi6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SWI6_3</name>
        <name evidence="14" type="ORF">HK099_008207</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000001">
        <property type="entry name" value="APSES transcription factor (MbpA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF3">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="13">
        <location>
            <begin position="150"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="HTH APSES-type" evidence="12">
        <location>
            <begin position="517"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="786"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="905"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="88"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1100"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="88"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="384"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3224598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1319" mass="151972" checksum="28EF54DCB0E9504D" modified="2024-05-29" version="1">MIFLIDFNSFVVGLTVGFLMNFFFIYVVVFKVLFKKKNCKDGNLSKEIYSDLDYHKKVTKKRKKRLKEFPKNVVDFLEKSLQPSSLINPDTNNSIATKHSKSDLTSNIPRSSSSPNLFNYSDEDNKNNPQLNRKFFSVEPLRSLINEKSETEKCEWLNLCFNRYFLILRKSVLFEIKMKKKLIKKVKNRLKSQSFVTDFDVFSIDLGDNPPQLQGWRIVKEVTDDLAVSFECDVKYSGGASVKLEVKSIAGSFPCIAEIKKLNGVLKFRLPSLSSPNKVSLQFLKPLPQESLIEFFIETEIVENFYIKEAIRKIIGKILILVFNELMVFPNFRSFFLPNLNPKQFNYWKKRKTEVFYEKTNGDKVKSNSQEEEVINFFEFDSEDLEGEEESDIDDANASSNDGDLKNDDAYENDGYNQNIKEHGTELQFHNSTVKNVQRPSKSFEHSYHFNKSTIINEPNLNKGINLNNQFLQLQPTQQLQQQQDPTLLNATSLNNNNEQQRVQSLKKPETVLSDKIFSAIYSGVPVFEMLCHGIAVMRRRADSFLNATQILKVAGIDKGRRTKILEKEIIQGEHEKVQGGYGKYQGTWIPFERGVELAKQYQVLEILNPILEFDPPTPGVKPEFNNRECLTKSQIKELDNLNNEINNNKPQKKKNLKEEFNPSEYIQNNHFVDSDGTPALKKLKKSANEKKNKKLEQLHGLQSKLQSQQFSHQVNFSKRQNEPYYLHNRSPYQRVPLENETFRPERHRGALMSIFLVEDPNYIPELLNSPNPPPDLDVNLVIDEQGHTSVHWASALARVTILSLLISKKADVTLRNFNGETSLIRSVLVTNNYDNQTFHLVVELLNRSIKLVDNRNRTILHHIALTAGIHGRAAAARYYLECVLERIARYDGNFADLVNVQDKNGDTALNIAARIGNKNLVEQLLEVGADVEIENRAGLRPKDFGIDCYFGFNEKKYPDDLIVEDRFDDSSVLNFSIDGLGENCQSISCEDSTSEHCLDETSHSLKNEFNYLSSCSAQSSSPYTARVMFPASKNGKSEKLDNKEKHLLKLEYPVEVLCPKLENKLDKTKREVSEKLKHKGKDSSEAIQKMIEEMSRFYISEIKTKIDSLNETQNNLRDITKELAFIRRENEMFKKENNKIPLLMTRIQNLESCLNQELNSGQEKDRKIFELENFINHFDKKEGYENEKLTQIEHENGNFYDVVGEQQKSPNSYQIQEIKLKKEIFGLKNSILEKEVKFKKFISYCAGIPLEGVGEVLDSLYKAIESDFESGINCLLLAPFLNKVKKLEDDINNGYNNHEEAGFIYTESDFFGKYHIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U553</accession>
    <name>A0AAD5U553_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008028</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the GSE complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000084">
        <property type="protein sequence ID" value="KAJ3224710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U553"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11384">
        <property type="entry name" value="RagA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.190:FF:000002">
        <property type="entry name" value="Ras-related GTP-binding protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039397">
        <property type="entry name" value="RagA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF1">
        <property type="entry name" value="RAS-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="285" mass="33306" checksum="007CD99F35F30571" modified="2024-05-29" version="1">MRSIIFANYIARDTRRLGATIDVEQSHFRFLGNLALNLWDCGGQDIFMENYISSQREQIFRNCEVLIYVFDIQSLELEKDFLYYKQVLENILRYSPDCKIFCLIHKMDLIQEDQQLPIFKEREQELINLSLPLTITCFKTSIWDESLYGAWSAIVYALIPNVKILEQNLNKFCDILDADEIVLFEKTTFLFISHVTKKQKKDNHRFEKICNIIKHFKQCCGKSQAQFLSMEVKNSQFSAYIESLTSNTFVLVIMSDTTIQSAATLINIKAARKHFETIGIEDKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5M5</accession>
    <name>A0AAD5U5M5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5M5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="386" mass="43475" checksum="64AE64D99777768A" modified="2024-05-29" version="1">MSALLATFDQLLADVDDFLIEMKEKEDSQDAVLPTPPSRNYENVSRVPFGIPARKTSLIPNLSTDIDSQAVYTRQAFLNRASSFPTASSGNVIPLNTLSETNSQIHTFSEERIALNPVGEVEQSNQRLSSLKSSHNSSSLPDRKSSITDGTNNKFSSNAPVQSPANTDKSFKATLKETISANQIAETPKIKVFESKYVYLEEPKRELPKYDYGLSNVVEVKAEVKPALIDNNLDSTKKCDSGTYSSDVPEVDNSEHAPTNRFQKQTLSRISPEEKIALQLQQEKIQKLHQDEALQQNYEEPYDEEDEEEYSEEEPRVLNFRFNEQTEIFYTYHKSEYDRAGPKKKSYEVADAEELADEEEEAREEAAAGIAHIAHTHTFKGNIYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Z8</accession>
    <name>A0AAD5U5Z8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Proteasome regulatory particle subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RPN8</name>
        <name evidence="9" type="ORF">HK099_006587</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Z8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08062">
        <property type="entry name" value="MPN_RPN7_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000004">
        <property type="entry name" value="26S proteasome regulatory subunit rpn-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033858">
        <property type="entry name" value="MPN_RPN7_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF7">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="MPN" evidence="8">
        <location>
            <begin position="12"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="942"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="984"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="1026"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="1074"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1190" mass="134573" checksum="B4C3AE8C1BDD6B8C" modified="2024-05-29" version="1">MVTASSSAPAQVVIHPLVLLSVVDHYNRAARNTKKRVVGVLLGQYNKDKVNVANSYAVPFEEDEKDPSVWFLDHNYHEAMYEMFKKVNAKEKMIGWYHSGPKLRASDLEINELFKRYTPNPVLVIIDVQPKALGLPTDAYFSVEDVHDDGTATTKTFHHIPSLIEAEESEEIGVEHLLRDIKDNAQGTLSTKITNQLNSLKGLETRLTEIKDYLEKVKNGLLPINHQIIYNLQDIFNLLPNLNIPAFAKSFSIKTNDELLVIYVCSLIRAVIAMHNLIENKIVNRDAEKKLDEKEEKALNAPAADVVETVKALNFNPSESKPYQVTLSHFQIPHLEASDYRSAYHQLCDWLYGWNVSDGLNDEDGDLLKSKRVPRNIDLSNDIELVECERIMASFQTLFYFSQRQLHKYYSSIEIKLPRVGGGYNTIENSSNAPLDRRGSNLYDAELDSGDLDNEMDRVWATKKNEQSDKKNDEDDGHSVKSNESLDLAVEMLLKNSNKGYVVKAAVVRAEDEVIKNSPSRKDSMEVVIPPDIVVVEEVNEDSSNATDNINDTAVITSTLLFNDAITNLNTSNNEPSTSTSDVDDIEVVKKVKEEMASSNSIESLEKVKQDNGSNEVSDFIEENLNQNKSDGDEEKLKKIPDIDEKFQESVTGDRTDFLPTISQSTLVPPLTNTLNASDTASAIPNSSITMLQNAVQPPFSFMKPGSSLKNLHQQQQFNSQEKSFQTQENLKKDINSLFNEIDRSCDYTLLCMVNLLVILTYSELLDHKEIYQKQLQTCHQLAADFISNTLKSVWDLLNKEFDNDVQFSEVRDLNAFKLRLKQMIQSRAFPKSQSVNNNTRDAEVNKKVKYRFSKLHKKFELLHILFTSVDIHLFPRFVEANKDGCKSAAYSEFDSALWLTGGYDGIIRIHDLRPGIVTGVDVAPLAQCMLTETMVYYFILVVGHRSIVSDVHFTKKDSHIVSCSFDRTIKIWSAQTGTCEKTLTGHTDSVTTCHLTKDGRYIASGSIDCTVRFWDMLNGECISVIKKHSRWVKIVRFSADGRYLASAGLDRRIYIWDVKLLTNAKTISHTRCIESHTDSVLDMAMSKPGILITCSRDSTVRVYDFINGHEWHCINLSPSWACSVTISECGEYFATGAFDNSINIFKTKSGDHIRHLRVFNFGILCVRFPKDLEYIVVGGNEGFLQQIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6D3</accession>
    <name>A0AAD5U6D3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6D3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050886">
        <property type="entry name" value="RNA-binding_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48024">
        <property type="entry name" value="GEO13361P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48024:SF56">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="306" mass="35891" checksum="8E115D0291CC43D8" modified="2024-05-29" version="1" fragment="single">LSWTTSDDDLKKFFSPYGTVTGTKVIKEKETGKSKGYGFVSFKSEEEAMFAVKSSKGRELGGRQITIQLAKERPENTNKFANIDKKEQECVSVISSASYRDPLEMLNEDEKISNFDLIARSAEKIDFFELQRIFSQQNLVLPRRSDFSCDRVGGNVDKFYSNLNNFSARSNDDYLRENRSSHGSTSSIIYGYDKDRDFLRESRDYVPMYHDRTSEHRCINDSGRKRSRSPYDYRFNDKLSLTSYERVRERSGAFYDKRTRDRSPYYEKRIIDISPSLYESRIDRSPTMESRIRVRSPIYNGRSRFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6U3</accession>
    <name>A0AAD5U6U3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAC3/GANP/THP3 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000034">
        <property type="protein sequence ID" value="KAJ3226520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="2">
        <location>
            <begin position="161"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="528"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1525" mass="176086" checksum="D05004ECA7AE6A1B" modified="2024-05-29" version="1">MVPVNPAEAEEEEEGEGNLRTNVSAFKFNPSATPFQPADDTAAIKSVDLNIGANQEESNYAASINSKPITTLKTFGTSKVTNEDRAERFTKETDIARRWEQMKKERTKLHAKYVKEGKMASVEHQGSLEEAIEIKGECETMCPEFEILDREVTNGLDFFEKKTFDYLMGVLNEHGLAATYSFIRDRTRCIRNEFTMQRWTGKEAIECHERCARYSIMCCHDLCESVKDIHMEHEQLRKTLQTLKQYYDDSSIVYPNEAEFRAYYILSHLFQGDIAKLAENNWRKEIYFDPRVQLALEIQSLAQRNNDKIKPVTAGARQNFVKFFKLLAKVETSYLQSCLVHIEIKGIRKHALKLMQNAYYFLNSNGLPMKDLVSMLCLNNFEEAKALLDYHAIPYFYKVNESDPGQIFDNSMNENFVVKIGKVFEKVSSAFGEKKSITVNFEEEQNKLVYDYKRENFILKKRESLNDVDIVLGKSNVLNPTPMQSAFSSSPQLNNKSNFNFSNSKHLFVKNENIVKPNNPLTPLSHNSSVQQQSQPSTQVSTVSPKLNIQKFTDTPFQASNGKPYFFAQLNTAANTAPTNNFNFIPHMNNNIFALPPQSQNATPTFNNQNHHSFSITTENRLATATAPHFHTATYSSHKSPTYIPSSPSIINSIPMQDLSAQVTPANVKVNKSSECKQQKSFIISTSSTSNVTKNFQAVPVVAATYDFASEFLKGNPEDHVMGNLKNLAILQKGQNEIILEKVLDEIAYEIVSEVTLAVSHKIFQEVMDNERVNLVIDELANDILREYVSDEISINVPCIPSVNNESLNQYRTRTKPSIFKQVFNVQKLDLVKQRVNSRIKLKYISFWRNRIIKINEVKNAEKQKLTKKAVDFYKSAIEAGPSIFGKVVLDDTSNEYNGNGIEQQEMFNLLELNDVAKISLRDSSLFQSKIAKIKVEISNGLLNSVPFNTLYQKYNFNFKCILGTTNDIFEIGNGLDADIKILQRFSVNWLLGKFIGKEVVELSVDKENLLELNKEIFKMEAKDSCYNEGSYFCRFLVQHFKTVFEEPCYPLKENAKSAFSGITVAMYQFSVFNYSLDSNLKSQFWNFERKKFYFFLSKFPLNSNIPLVLIFWDVANFFFDDLDKFNEECEINLNLQSTIKEGPVLDVTCLLIPVYNIPAFGMGFNKIEAEKNFLNRMHWLGQRSCQIPILRKTIFEDFVENSAYVYLINLYKRVTMLSSARLICVNVELNLEVFKKLIELLNILIETIIEILTDNRLKNVCYPPIEWTKSRYENENTADYTEFDDMPQNISWNSDEKFTEIKKKLECFKINLQHHSSHVEIINNVQKSINLRQVFKLVFLLIIIRLLQDIYKKFVFDCLLSIPHFDRLTIQHLITVIKQEISNFERKIYDDLVQFPFDEILIHITQALFCSLKKENINYFYLQGRICYFEAQFKKVLNLKVNEIENYLKIFFEESNSYLEDLTSRKRSRQLLDPKKIQEIYKLDEEKAKKVKVSLEAARLKTVVENANKIAEITKKKIFGTDIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U780</accession>
    <name>A0AAD5U780_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Monocarboxylate transporter mch1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MCH1</name>
        <name evidence="6" type="ORF">HK099_001186</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000131">
        <property type="protein sequence ID" value="KAJ3223413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U780"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF158">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 12-LIKE CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="44466" checksum="E1662068B08D1CD4" modified="2024-05-29" version="1">MGIIVDKFSSKIRFIFLYAAFMISSGYCLIAATYAGYISLPSYLFVCFYFFLVGHGSAASYAAAMGTNVRNWDNKHHGFAIGVPISCIGLSAFVFTQFANFFYIDAILDISSFLFFLGVISALANVIASYCIRDVRHLKPARITTQSEENQNLLESEESVPLLEEVLSVEELFPKFLSSFNAYLLALMLFIVGGCGLMYINNVGSIILSLTAENQGTQSPKVQSLQKFHVALISISSFLGRLIFGILSDFFIKSERFCFKKIPRVFWVGFSALVCFFGYVLGSTLGGYGTIENNRSAMQLTLCTIFIGTSYGAVNTSMPVLVGLLFGMKKYATNVGLISMFISIGSMFFSFIFSELYEMKRDSEMEYCKGQECINLTFQISALCNIIAVFLGILIWRRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7D5</accession>
    <name>A0AAD5U7D5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Pheromone processing endoprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">KEX2</name>
        <name evidence="18" type="ORF">HK099_006402</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S8 family. Furin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000055">
        <property type="protein sequence ID" value="KAJ3225681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7D5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007323">
        <property type="term" value="P:peptide pheromone maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000026">
        <property type="entry name" value="proprotein convertase subtilisin/kexin type 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000005">
        <property type="entry name" value="Proprotein convertase subtilisin/kexin type 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884:SF14">
        <property type="entry name" value="NEUROENDOCRINE CONVERTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 14 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14 15" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="679"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="17">
        <location>
            <begin position="474"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13 14">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13 14">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="13 14">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3225681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="754" mass="83682" checksum="32C526F5BBAD02FE" modified="2024-05-29" version="1">MIVSGSKKSYIQNHLENNLKIGLNDHQNFYYFVIKTQQDPTILSIENSNFHYLGQVGELENHYLIATQKEDSNAEQVLEVEKNHRTILKKRLSDLIEFEELNQQLPRKLFKRKMINEVNNDCLRKKNVLEARAIPKMNPIFQGQLGIRDPEFQKQWHLVNLESIGNDINITTPWAEGITGQNATVCFIDDGLDYDHPDLKSNFYAQGSYDFNDHRALPKPKLSDDRHGTRCAGEVAAIRNDVCGVGVAWNSKVSGIRILSGDLTEADEATAITFDYHNNHIYSCSWGPSDNGQAMDAPPKLVADAFYNGIIKGRDGKGSLYIFATGNGGSLGDNCNFDGYTNSIYTITVGAIDRYNNHPSYSEECSAQMVVTYSSGAGSHIHTSDWPAACTETHGGTSAAAPLASGIYALVVGIRPDFTWRDFQYVSVNTALPINLQDSGWAKVAKNRLFNHKYGYGKLDAYRLVEFSKTFKLVNPQVSFRTPDVIVDTALPHNGEGIKSTFLLTQKHLDGINFLNLEHITVTVWITHGKRGDVQAILTSPNNYTSILATRRPYDTNMGGFQNWTFMTVKHWDENPVGSWELHIFDSIGSEKVGRFNSWSMTFFGQSKGEPVLESTAAVVAPSSSATTSSSSTVRTTTILSSTASKSISFTTSTSQILEQTSNTHATAIPSSSAGGTGALLFFGFLGFAGVILLALYIMKKKKNFQDNRREFYNFEKVDDDGDEMLNAFGLDEENESDVLFERGSSVEISRADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7H7</accession>
    <name>A0AAD5U7H7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Target of EGR1, member 1 (Nuclear)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TOE1</name>
        <name evidence="4" type="ORF">HK099_001675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7H7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF37">
        <property type="entry name" value="TARGET OF EGR1 PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="305"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="2">
        <location>
            <begin position="305"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="512" mass="59322" checksum="58BDE437FB09332B" modified="2024-05-29" version="1">MSKLSKSTLPTPTIPNFNEVNRFNVQQLQLVINHLITNADFVSVDCEFTGLGENKLTKAPNIEERYGHLSKLVKSHAIVAFGLSIFEKGTENKNTFKVNNFNFTMLCSKEFNVNHTSLSFLVDNGFDFNNQFINGIFYTPGEDKMQEKNQSTKKYAFNQECNEEIMKQNNAIRSIFSNLLNKPNLKVVIHNGLLDLMFLYHSFYTDLPLLFSTFITDLTQMFQGGIYDTKYISEFGLHREESSFLAYLFRNEREQLDFKFSNKAEYLTCEVQNRLSLPSSFAKKEETSTKEVDPQIKSGKRKTNEVDKPYCENYANHGYCKLNKKCSKTHDLDTILDFQFGESELKKSKKLKSAKILQQNTQAEKNEVENGEKATLVKNVIINNVGESTEIERKNNFAKIKEVEDKLNMLKKSLPTYSAESTVERTKVKNPFENYHSACFDAFMTAFVFSHQRFKYEHFIAGDKHLTKKETDFEFNKNKIYLMGKDFPLKIEKSMYSKFSSGHLKKWNELFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7J1</accession>
    <name>A0AAD5U7J1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7J1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.230">
        <property type="entry name" value="Doublecortin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036572">
        <property type="entry name" value="Doublecortin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="168" mass="18912" checksum="C1BA7C3D46D43D26" modified="2024-05-29" version="1">MARSDEVTARLTDTSKYTGSHKERFDEDGNGKGIQGRSNRVLNDGSTSSSSRNHELDGSVKLEKKVVVKPKTDSETYGSKPKVITVYQYADKNHTGEKYVMTKQKFPTVKQLNEATIKLIPTGKPKLLLNRDLKEVKFDDLVDGEKYLSITAFDLKKLETQKLPAKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Q5</accession>
    <name>A0AAD5U7Q5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000151">
        <property type="protein sequence ID" value="KAJ3222951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Q5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="630" mass="73885" checksum="FB16D9FF9D6A9C3E" modified="2024-05-29" version="1">MEEIFSLITSQTKSIYFLIFPDTVEIIEKFTPFVPPLAATILIFTKNERELPTLNKLKYTSNFTKRLNIISCDQNLDLETMFSDCVMKLDKYCKPSIDFQFVFSEKRVNLLNIKRKYSSQRFKNYTFNFLTKNFLNEVSIWKNFNEYLDFNLINSKRLNNDLEDLLKFLKAKFRADEELFIKYQTFDLKKFSDILIAIDKTWKHQYDYIHVLNGLIEIKMLELVDYERYLFKFVRQDEQIEAASIYNRNSSAVNDDTMDQDFKDEKTLKRIIDDKLQNSIFKNDDAVVSIRCKDSTGSSEITAYCNDDETTASAKIMDGDYENHYDKKRKLGLDTSIHNNSLDEHNRGNFFERIIPPPYFESHCFTNSKSIPSNTAVEKDKFMNQKTNSNNNINQVINNQEKRKDISAFVTDLTWCEKLEEFLKIHYPSENSPSYKIISLKDLNYPKVLVQDYAKCDFQCEIIVVEHVFKTSRSFSTESEAKEECAKLACKFMFSFWEAAKESKVLKGKLSTLFQTEENRKQNSENPETDKSYIVEENMIPDLNMRKKGEKSSVRNLITYVNNLQQQRKKANSAIEKEIIPVESFKVEGTAHICVLEIFGKSFTSSPKVKKKEAREEAYSFAFKEKNLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U843</accession>
    <name>A0AAD5U843_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001263</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000134">
        <property type="protein sequence ID" value="KAJ3223341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U843"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051848">
        <property type="entry name" value="PGIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059:SF30">
        <property type="entry name" value="OS06G0587000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059">
        <property type="entry name" value="POLYGALACTURONASE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041983095" description="L domain-like protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="36672" checksum="6B0562C0A18F10FC" modified="2024-05-29" version="1">MKFSKILIAVGSILSSINASKPPIDPEKYLQSNDCLTVWAWLPQIYPNGIHDCCEITADNKESMPLIITCDINKRVTAINIGIEYNPASTLVKGNWKSNGFGILNAPLPAYLGNLTELTTLYVTGAALYGQIPIELSKLTKLQHFSLSNNALTGEVPAGLFTDMENLISLDISNNKLTGPIPDSFVNLPNLISLQLDSNQFSGPLPDLSYLVGIGEGPKYDIANGGFDPVCRLNNLGPKACVNSLDDLKKVPTTCTLPVPELKVCVAETIKTKPTPVYQQAEKRGDGLNDTGKVVVGVLGGIVFLAGAYLITFTLIRKGNAKDAALHEMTKKERLDRASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U878</accession>
    <name>A0AAD5U878_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U878"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="339" mass="38948" checksum="125DDC911533AADB" modified="2024-05-29" version="1">MFLVSSTIKKRKPSFCELELVEIFEKGTTTSQEDMYSSEFGAGNPTTLNVNRAHSENFLQSNVINNHTKKNSSRFSLLDPFKQVDFNSTSLFDTITDNSPKTMTLPLSKINKNADINSILEDKPPKLISISTLDYSTSINNIPIPVNLISQIETELFNEEFQFKRGHNYFYESDTGFVGIEGKVWLGTCWPENLEILEIFKNVSILHRPFEISEEIKSFTTFSSTSPSSGSLKFKSQLSKQNKSQPVNRNTNKYNSNFNFKFLINEKPIRIEVLTYFQKNLNLLNSVKSKTYGGKFLIDVGGNMYKIVKENKNEAEDKLIYFCNWKDRRDNLKCLGLCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8C0</accession>
    <name>A0AAD5U8C0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_006031</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000987">
        <property type="entry name" value="DEAD/DEAH box RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040801">
        <property type="entry name" value="Ski2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17911">
        <property type="entry name" value="Ski2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="11" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0408">Iron</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="338"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="601"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="546"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="566"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="1705"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3228151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1760" mass="199762" checksum="125F5133B38B8A58" modified="2024-05-29" version="1">MVDLSEAESVLYTGKEEEFPFEILSVGQNTSAELIFKHNPNILSNSDIFMNLANFGSLSDFNVELEDKYLTPKRILTPSLLNHAQRVLEVEQDYSETLNLQLSKNRTDINFKRNILTGKINFETDFNEVMLNSLSESNPKNSTSLQRDPAGYQNFVTGKSTNYPFTPGGIDFLQKVKVEVQEFNLDDLINEEEGLLTIAPGFERGLETMDEGKNTERKGEFFSTKEYTASLATVDDDILNFLTENVDSVGNGAEVLIEEETQAEEKKTEEKKEVDDIIPTLSLKLPKKNKPVISSKVALKEWAHMIDVNLDFPDFHDLVPDMAFSYPFELDIFQKQAVYHLEQGDSVFVAAHTSAGKTVVAEYAIALAQKHFTKAIYTSPIKALSNQKFRDFKNTFENVGILTGDVQINPEASCLVMTTEILRSMLYRGADLIRDVEFVIFDEVHYINDSERGVVWEEVIIMLPDHVSLILLSATIPNTKEFADWVGRTKKKNIYVISTLKRPVPLEHYIYYDSNIYKIVDSSKKFLPLGYKNASDALNATKKKEIVKKDNSANTSRGGRGGRGGQNSNRGRGSSNTGNRAGSATNRAQTDKNLYVSLIATLKKLNLLPVIIFTFSKKKCEEYCAALSNFDLTSGSKEKSEIHLFCEKSLSRLKGLDRELPQVLRTKEHLLRGIAVHHSGLLPIIKEMVEILFTRGLVKLLFATETFAMGVNAPAKAVVYSGIRKHDGQSFRDLLPGEYTQMSGRAGRRGLDTTGMVLIACSDEIPESLRLNKMLLGTPTKLESQFRLTYNMILNLLRVEALKIEDMIKRSFSENSNQKLIPEQEEKFKESSKRLAAIKRLNCNICDSDIDEYYDVSAKITLLNHELREMFINTPIGNKALCTGRVVIINNSFYRNSIGVLLPKSGFVSASGMGDSKSYTVFILCRKREKDYIPSETGSSHTFPLLFSIFTEFAPMPVTSVDVPMSGKVSHDIISIPYTDLSTVTKYEIKLESNFNPEVRSQAATVEDKLLQIALEIMKRKDTLEFDWDKIRNIEFQEKKRDKKYLLSRLTGFDCVQCPELIEHYAKIHMEHTLQQQVLSLGNTISDQNLELLPDYFQRIDVLKYLKFIDESSTIQMKGRVACEINTADELVLTELILDNFFAEFEPPEMVALLSCFVFQEKSQSKPNLTPNLERGIEKIQELAIRIAEIQKSCGLDIAQHEALGRINLGLVEVIYEWANGLPFKHITALTDVLEGSIVRCIVRLEETCREVRGASRIIGDAKLYKKMEICSEAIKRDIVFAASFLYTNIPSFNGGLPFFGNFFQFLKFGKINKLHDLFKEMNKDESIVTYSVFFDLGISTSKAELVKGILNSKSFVRDDFAVRLFDGISKYSLFVIPTSDLWKKHRKMIQPAFAPVHLERTFHVTMEVCERLFEKIGDIKHNVPMHQYFNYISCDVIGKIAFSYDFEFTSSINNVNDPKYNVLHQFESINDAIGLRFAAPKPFWNFIGAYPMKGSFASISETIQKILEEKKKRISEHKSYADAAGGMWEMDVLDRLLENSYDAANNIDDDKKPPFTDEELCDEIFGLFLAGHETTSNSLGYMLLEITRNPLVEKKLKQEIDLAFNNITFTYQKLPELKYLDCFIKESLRYHPVLPGLTKVADRDDYLGEYYIKKGTPVTANIICIHFNELYWKNPNVFSPERWENNFTPVTGSYVPFGDGPHNCVGQKLALIEMKVVLSVLLRNYEFTTTEGQTFEGSCKLTMSLKDGILINLKKRILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8F7</accession>
    <name>A0AAD5U8F7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Chitinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_000045</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8F7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053214">
        <property type="entry name" value="LysM12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700:SF2">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47700">
        <property type="entry name" value="V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="2 8" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1158"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1192"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1215"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="12">
        <location>
            <begin position="221"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="12">
        <location>
            <begin position="284"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="12">
        <location>
            <begin position="346"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="12">
        <location>
            <begin position="414"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="11">
        <location>
            <begin position="475"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="13">
        <location>
            <begin position="542"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="499"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="522"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3228490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1279" mass="140976" checksum="64DAAE41593F96A8" modified="2024-05-29" version="1">MYCGFLINSKYYKAYCVAHLLFGNFTQIDDNICPQLESFADPIKFNATCNDALTNYQYMGSYNFQEITPKYYTYLKENNKLYEKGSNEFTARETFTSIEPTIVPTTIITSELYDMTRTVFQTLSSETVVTYVGEFTSTKNITTTITIPIFPTTTKLNGTETKTLTFTTTTVKTTLWPITTTIKSEYTSKFFIYTTTSVSTEMIPKFLITLALSYIVHSACTTQTVSAGEGCWAIAQRCGITVQRLEQLNPGKCNNLQVGQKLCCSEGSLPGPTIPPGNSDGTCNFQKVVAGDGCWSVAQRCANGIDSDTLNQINNGACSNLQIGKKLCCTQGTLPKPKPDANGNCIVYQIKTGDGCWSIANEIGVSQAELEGYNRNNWNWKGCDKLALDQKICVSPGNPPADPRPKPDANGNCFAYNIKANDGCWSLAVIYGLTVADIETFNKNTFHWVGCAKIQTGMNICLSSGSPPLPPIDPNAQCGLTSVNKLTGERNVKCALNACCSTWGYCGTTEEFCIEKPNFTGCQSNCGMGYPFDKTSPAPHPQYRIGYYESWTVSRGCEVMTVSQIPVSKYTHIHFAFASVSSLFQVEIDPKVMNIFTEFCNLSGVKKVLSFGGWAFNDPPTQTRFTDMVTSHRSTFISSVLTLLSNYNLDGIDIDWEYPSAPDRGGKDSDAQNYLLLVKELRAAMNSRYSLSIAAPASLWYLRGFAIAEMSAYLDYIVYMTYDIHGQWDYSIKWTGPFLKSHVNWPETVDALSLIVRAGVPSSKVLLGIGLYGRSFKQSDPNCSTPLCTFQYQKADPGPCTKEGGYLSMNEIKNIIKGGSVRSSYYDQEADSMVLTFGNDHWVAYTDSTINEKRRQEAIRYNLGGTVEWAIDLDHDLDIVDPNMKSRNCKTNVNSLDEITGMDPICVDSLIVGVISNDLQKALGSYKDIVANGKYDRNFGIYQHYLWQSLPKEIDRFVGANGDKYFNCQEHRTIFCCKNVGWMGDPRGCTPGNDCVGGKVWTKSSCPKYIPGIGNAAFENIIPVKYELRDANGFNDAMLKEVGVQPTWIQFSSRTVKAQPSCWMVPKPGPECFVVWEGLPGLNSKFEVPNPKAAIEPMLQNYTNGLTGLDRAEIDMMALGDVIDASVVGVYMASQSVESMQKISELGEKIEEEQKKEMILSFINFFLMLIPFVGPAAVAAEGAIMTVIINSIRVLGVLTDVGMAVYDLITSGSPFAFLFGLIGLFGAFGDAVSMAAREANFAKLAGIKRGIKDSELISLGPKPAEMMKKIDGLKLKCKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8Y1</accession>
    <name>A0AAD5U8Y1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Leucine-rich repeat-containing protein 71</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">LRRC71</name>
        <name evidence="2" type="ORF">HK099_006753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000060">
        <property type="protein sequence ID" value="KAJ3225480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8Y1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053040">
        <property type="entry name" value="LRR-containing_protein_71"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46984">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46984:SF1">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 71"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="561" mass="61590" checksum="DE1283823306F59E" modified="2024-05-29" version="1">MAILKLLKEQPLPLPAAVAASKVTAAPPPLPQKSLNSRKETTVADFVSINNTQTIENSIQDNTLFIANSNNAQSENLIQSQILNLSNNQDNLKTLETFELIPKKPSKYVFTPTIVLISDSINACANQQDTNDSATVEETEFFKLSISGWKVLDGTVDAIALCLPSSVSLTTLSFWNSGLDDTHFHQLVAVLSLTNIKNLSLDQNPSINESNYHLLLNEDSQLKSLSLRSNFITDIGCKLISNCLKINRNLNSLNLWNNKIGKEGADSIAEALKVNQSLFSLSLGRNLVGDDGIVSLCKEASTGKKIRNARLQTPSQLAALRKPSARPKDQEDPQQATLQTKNGSKPEGNDSQNTTKKGQKLTKKEELEKKKLESAPNNNKDTGNTGNKKPNVQNKKNSPLAGGLGVIAGGSKEDLKNIGKDKKSGKDKGKGGKVKQDEVKEDVEEVANDVGTMEPMFELNGQYFIIGNRSLNNLNLEKNNLRVNSLKLIMDVLKEQELSQEIGLFRISLKDNNFEKENQLYIQIQNSLSTRNPFLEIPTEIVEKTVLENVIEGGSEISTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U943</accession>
    <name>A0AAD5U943_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000053">
        <property type="protein sequence ID" value="KAJ3225760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U943"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052562">
        <property type="entry name" value="Ketohexokinase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774:SF3">
        <property type="entry name" value="KETOHEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774">
        <property type="entry name" value="PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="1">
        <location>
            <begin position="155"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="515" mass="57872" checksum="7D8A4ADA92BD467A" modified="2024-05-29" version="1">MVTKEMKNFNQTNFTHKLQLTKDYESIEDLLNFNTPTSSTFDQTFVFPKKASGLTVSTSNIISNDFESIQDLLNFITPTPKAEKNFNFFKKPLHSVPAITIGLYENNQKVPSPITPHLIVKSQNLPFPVYGSNVNFTEIGNTQPKVERRKKVKQACDSCRRSHLSCDDCRPCKRCVKKNGLCVDSPIDAKTKSNKKLQKVSSNSSLAAELSFSKEKRRTSISSIYSDDSINSIVDIGGEISMPFLDNINFVNNEDTKTRANKVVYRRGGNVANTTVVISKFNVKVNYIGVFAGSYDNIEKNSAVSDLKKRKSINLETSIFRGTDYEEPTACRTVINFVDIPELSFLEFKTVVDEAIKPKLLIKPCWFHSEGRNLENLDSMMNYVADLTDNLLAKEKKQINKLIISMEFEKFNRPGLEKLMALPDVLFFSKVYAEGMGAYGYKNLPNEKVVITPTKKIIVKDQVGAGDTFIAGMILCLSHDMNMKESLQFAVDLATTKCSIDGFDGLSELIKFPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9J9</accession>
    <name>A0AAD5U9J9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9J9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1660.10">
        <property type="entry name" value="EreA-like (biosynthetic domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007815">
        <property type="entry name" value="Emycin_Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052036">
        <property type="entry name" value="Hydrolase/PRTase-associated"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31299">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31299:SF0">
        <property type="entry name" value="ESTERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05139">
        <property type="entry name" value="Erythro_esteras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159501">
        <property type="entry name" value="EreA/ChaN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="211" mass="24475" checksum="E8CA3787740D1259" modified="2024-05-29" version="1">MKKLTRKNYEVLGSFKPEAEQYIRALLQNTVEPQNEKVSKILIELMKKERGKNLGIGKSIAVFWAHNSHVGNSVANADITAKIQYNLGFSERKIGSENSFLIGWLENEMDRIMKYSSQLSLKNSNSYLFHQLVDHSKNLRLERLIAVLYVQRTESESHYSLTKIAEEYDMIIHLDETSALQVCELINIRPGTVNYFRFEKIDPEMFELKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9R4</accession>
    <name>A0AAD5U9R4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Copine C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9R4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Copine C-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="355" mass="40092" checksum="41130DE46CB63615" modified="2024-05-29" version="1">MEANVQTYSVYTIFTESDSIDFENTIRALLATDKIPLSLFIIGLGDIKYTNLQKVFSDNGLYGRCVFPRSWENVKFVRYSDYEDVFDIENLLLSFLPEQVLEYMKNNNISPLVRKRKNSTHVTNPASPNNTISRNSVSTNPSNTFNLKVVTEDQAMRRNSTISHQRRASVVAKSLQTATAASLPTVAGSHKQQSRNVSSPEEKIESNRRPSRNFGSERNSCIIDNSLSPCTPRKSFTAAISHRNSLIHQNYLDGVLLKLSTESLLKDNELCEKQEKRPTAVESASSIEDKTTYSSETVGKHVENLELKFDKFEENVQNDLSIILDLVRGLGASLVRIENRISQLENQAGQRYLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9W2</accession>
    <name>A0AAD5U9W2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="1">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PUS10</name>
        <name evidence="6" type="ORF">HK099_006648</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000059">
        <property type="protein sequence ID" value="KAJ3225510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9W2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2510:FF:000001">
        <property type="entry name" value="tRNA pseudouridine synthase Pus10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039894">
        <property type="entry name" value="Pus10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048741">
        <property type="entry name" value="Pus10-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048742">
        <property type="entry name" value="Pus10_N_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21238">
        <property type="entry name" value="Pus10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21237">
        <property type="entry name" value="Pus10_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pus10 N-terminal eukaryotes" evidence="4">
        <location>
            <begin position="28"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Pus10-like C-terminal" evidence="5">
        <location>
            <begin position="200"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="474" mass="54387" checksum="A73BB07F15626643" modified="2024-05-29" version="1">MSLMFKCMNIIVIKTLMKDEKIKILALDEEILSKTEKSLQKANFNGLSSFFTSITVPATLAVRQRSISLYLKEKLSGNTLPEVVEVRDVVKQILGELLPNKLNLKFEKKCSFMVEFKFEHKESFFDDFDWMQKIEKSEFRVKKSRKRRDEIVYHGLSNEKILNAAKKLDYEDFVNAKQCPPTKVSTPCEVSIDFAHEQIYIAGRYNKLKRHISNSPWLINGKLKVPDSVESLMSSELQELFKCERFKFSSAGREDSDVLMLGNGRPFYFELIKPRNLVVTPFELKEIEDKLNQKNEGKIFLRDLQISSKEGVVTLKESASTKCKSYSVLIKLSSRPSEDMLEKLNSLTDVVISQKNPSRVPRRADIVRDKIIHSLQINESKEEMNHPETLNFVNSNGKILDSEMICRLDLKTSAGTYVKEFVHGDEGRTSPNLSDLLQIDKAEVIALDVTKVFLDWPESKGKGPEFGRDVEFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA42</accession>
    <name>A0AAD5UA42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Secretory carrier membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000045">
        <property type="protein sequence ID" value="KAJ3226050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA42"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055038">
        <property type="term" value="C:recycling endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007273">
        <property type="entry name" value="SCAMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10687:SF90">
        <property type="entry name" value="SECRETORY CARRIER MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10687">
        <property type="entry name" value="SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04144">
        <property type="entry name" value="SCAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3226050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="30280" checksum="EB198FCACA4D46E2" modified="2024-05-29" version="1">MSNPFMLESEMDSDNPFADPSVNQALTSNYTTVDARESVEIELSSASTSHDADKHYDGDLSNKKQPTNFDHLSKREEELKRREEELAQRERALRSEQDSMRQHGFHPPNWPFFYPYIYLDINEEIPEIHRGTVSKIYKFWLATVGNLLFNMLVCFILLVSPTANGGAQSPTVATDFGVALMYCFTITAASFFLWYRPIYNGYMKENSLYFRFATSGSAGFINLLGAFAAGKVFGGVMCIIDFAVWLTLGFVGLWTWKDVHHHYRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAI8</accession>
    <name>A0AAD5UAI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS6_1</name>
        <name evidence="5" type="ORF">HK099_001661</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00512">
        <property type="entry name" value="Ribosomal_eS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020924">
        <property type="entry name" value="Ribosomal_eS6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="653" mass="76311" checksum="128386C56B990B1B" modified="2024-05-29" version="1">MFKRILNECTSSEDFKTFATGWFFWKNSKTNEQLAAKEFQNIYKENMKEWLAWAFFTSSLENFDDKNIMELEKYISTIEKEKDVKFAKGYNNEISTVRLTFCPVEAFSKPFFMYALIYLMECVGYLFFRLYLNFRHKIIINETESIKDNNTPYKHFSYYYKKSKNGNNKTPLVFFHGIGGGLFCYAKLIYKLCKIDEDRAVFLVELPHVSMRLIGGDMVPDMVSTVKEVETMLKMYNFSTANFVGHSLGSVYWMTKYSKMVSSVTFIDPVCFKLYDSDVCFNFVYRKPKTATEFLIYWVVSREIYISHFITRHFIWHHNVIFPQDLPKSSKVFIGLNDNLINSRKIARYLNDNGVDVETFQDLDHAGFLFFNKMENRIIQSVEKLMKDVDNRMVLKNTSNAMIRTKFKDSNSFLNLNISYPATGANKSIDIEDERKLHSLYEKRMASEVKGDALGDEFKGYVFKIAGGNDKQGFPMKQGVLVPSRVRLLLSKGSSCYRPRRTGERKRKSVRGCIVNHDLAAISLVITKQGEQEIPGLTDVQLPKRLGPKRATKIRKMFNLTKEDDVRKYVIRREIVREGKKNCSKAPKIQRLVTPVTLQRKRHLAAKKKQAIEKSREQKAEYAKLLSLRIKERKEKVKEQRRLSSVRRSQTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAZ9</accession>
    <name>A0AAD5UAZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA replication checkpoint mediator MRC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018564">
        <property type="entry name" value="Repl_chkpnt_MRC1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09444">
        <property type="entry name" value="MRC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication checkpoint mediator MRC1" evidence="1">
        <location>
            <begin position="722"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="957" mass="109090" checksum="240C40503BD5062B" modified="2024-05-29" version="1">MKKFRSILDSDEEIENEILLAALKKPTKIVEDGESCDEEITDSLNNTTTPCSINVGEGSLEDNLESIQNTESHPARVGSRIANLKPRNDKFEKSKTFLLQKRAQKTLNLDLDKNSTTSQNTVTIDLQHHSSDEEPFDWDLKSNIISPEMVNYKGQLTEVDIQSETEDLNIKPVKKRKKVENMVFSKKLIFETELETQRILRAPVNNVPIKKGKYNIDDFMAERGIKRSLSYKKLLMIGKGEEVEDSNIDFVQTADDNSNNNQAINDENVDKNDEKLFQNKNNEATFDEVDFSKEDQDNKKKDAEHISATENKTFSEIFKKKLPPLIKPDTKVSLAEANRIFGAQNKILANLLIDDESDHLEIIEIEKPVKNGTSISLSQTKHQLHCNLLQRAHQLSNIERQRKDLLIATKRHEIETAALNKWVEKERRDKLHEEKKKQREAEKRKVVIPTEVLTTQKYENGTNELRESDISQVDNNNISEFITNNEKIGKVPIDIPHLLTSPNQNRTGNISPYSSPSISHNIIEFDVSTLPHSQNFTYKIGDVGMMDNGSFFHFSLPRYILYGNLLTSFRCEESIAMLSLTETEIENTVDFDSKIVNAEKGEFFLGDGLLEDSSKLQNELNDLLTGVVLSEKIPKNKTDLTLRHIPMTDPAVAKSPVMPLNESNLDVFDKGIQDFTVPGIKLKKGRILETSDEEDELEDFDGRKENKQNFYSFQLPTNAALEKSKFVETEAEEEEDEHKGLGGVDGDEIHDYVDEDPLLIVKDNEVETNKNLDKVLRLHQLQLKEQDEREVETIIRDVTSGALRKKGFGVAARANRERSGNGFELDDSDDDEEMINRIKNKLAKYNKIDKSDKLTNMERYAINPETASFAEHFSVEFGDMEGYLSNCSETSERIEGTQVIDNVSLSPVSFPIQNFNGLNNKEQENIENQLLEKKEIKRRGEKGQLFQKKIKSDNTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBT5</accession>
    <name>A0AAD5UBT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBT5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="285" mass="30738" checksum="E0289E5A57597F15" modified="2024-05-29" version="1">MDPPPLGGPPPPSRWNIAANICDGMILGSCFSLIVFLLIKLRFTKFSIVQLIGLVAYIISSSAYTTLNGLPEDFKLYNIAIASISNAFGRAMQSEIMTQFYITLTNGVSSEKRKMIFAGIGRLMWVLVMLAGIAEGTVFMIFGPGIALHNQVVVVAVTYISLLCGLVNAAQFLDMILVMTDAHGRLMESLKNKNFLQLFVLSIIVLGSEILAAVISAVAISAASNNRTDPTISIFFSKLTIITSCVGLVLLQESIVKYVKARSEAITKSQTSRVKSSTVKSSTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBX4</accession>
    <name>A0AAD5UBX4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cell division control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CDC6</name>
        <name evidence="10" type="ORF">HK099_006035</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBX4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016314">
        <property type="entry name" value="Cdc6/18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001767">
        <property type="entry name" value="Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="180"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="50"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3228155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="597" mass="67625" checksum="9484E1873A01DC90" modified="2024-05-29" version="1">MINASTPRRSARISNTANRKVLGVAPLHDLNNVSNSSSVADCKFLKRMRSSSEEESKDDSGSMQNRALKLKKAKTGEVSKESSDTELDKENLNDEEQNGNLSDASTAFRASLENIKTPQRRKALLVATPKTPSTPKTPLQFINEAKSAFKRCSTPKKLVGRVEERKFLENFITEHIVKGENGSLYLSGCPGTGKTALLDEVLFNSMKKIEKPRKYKIKFCKFNCMALKDPKYIFKIILKDFRKIKDLDSFNIKECIDILSGIFISTDNNQCSNAKSNSFLKKLMSESKAHLKESVIILDEIDYLLTKDQEVLYKLFEWASHESSKLVLIGIANALDMTGRFLPRLRAKNMEPKLLNFKPYEINEISDIIKDRLMRLYDFDPGDNKRDVANFPLMQDSAIEFCARKLVGIGDLRKALDVCRQSIEILECEYKKENCNEDHGNKFLSLQDVPKVTLRHVSKVTSEVLGNSSTGVMKVKNLHLHQKILLIAAVILEGEKKSELSISKLQEEYFNLCRSSKNNLPPPVSRSEFQDLVNLLEALSLIKIVLNFNKLSYKSICPGSSIRDKSKKFFLNIHPSEVMRGCQDMKILEEVLKTCNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTJ8</accession>
    <name>A0AAD5XTJ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007714</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ZNF277 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000775">
        <property type="protein sequence ID" value="KAJ3212522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTJ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040048">
        <property type="entry name" value="ZNF277"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13267">
        <property type="entry name" value="ZINC FINGER PROTEIN 277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13267:SF3">
        <property type="entry name" value="ZINC FINGER PROTEIN 277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3212522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="565" mass="65971" checksum="559C36352A555ACB" modified="2024-05-29" version="1">MSKSSSMSFPNQSDTESEEFSSVELISGSNLLIIKTKKSSLTLNKEDIDVIDDYNAGPFSPHSNLVPTKNAGIPFSKTQEKNKVNAIENTNSINSPSNITIKTKKSQPNLKSVHVEDDDDDDDDDDDDNAHSFSQKYYFWDSTEFICPFINCSQKSSVSEKKLPQNSKAKSTNSVFTDPLIAKKHLRTEHHVEIVDFLDTLPYLKAYLNFFLNKIIEAKKLNLKRTEKQDFFFYKNGIYLLGKSKFDLVMRKEFLKEKMNEKLAIQTEDRQCDSPSVLQCLFCRNSFKDRIKNFSHMFKEHGFHIGLPDNLVEVEKFLQALKEKITNAQCIYCEKLFINTKVLRSHMRKKKHFRVHSQNHFYDKFYLCNYAPKTNTINPPTESTKKNLIAIKNVESSTDEETYDDWSEEEEIPSQCLFESKTFKSPLETFTHMNAVHGFNFKELSKSLTFYQKIKFINYIRKCSLKFVCFHCSKKFDREKLFLQHFEKTNCIKTFKPKFGKDSNGSEFQSFWKDSNYLFPTIENDPLLFDFGEESEFSDEDHSFKLSDKEIELLKLKCLEIKELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTM3</accession>
    <name>A0AAD5XTM3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Melanoma-associated antigen D2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MAGED2</name>
        <name evidence="3" type="ORF">HK099_007480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000729">
        <property type="protein sequence ID" value="KAJ3213276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTM3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50838">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="2">
        <location>
            <begin position="45"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="31415" checksum="479D98AFFF47E8C7" modified="2024-05-29" version="1">MVSKKGKRNESSESDESSVEEIRTTSRQTQGENSMGNTDSIQREFNRKAIVLVRLALFNQHKNIPLKKDDIVKKVLKGHSRLFPSILEIAQKKLEDLLGMELVELPAKEKTSDIFASQRGGSSGKTRSVSSGLYVLRNKIDFDLREEVVEVENETAPQNILLLIILSLIYVNLKELRSEDLFYFLKNLNLLQGKNYPELMPSYTSMLTESKGGGTLDTLIKTFITQGYLLRLKVKNHAQSENNAASFIFRWGPRAKVEFSEEDVKHFIAEVVKEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUB7</accession>
    <name>A0AAD5XUB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate dehydrogenase assembly factor 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003298</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SDHAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002181">
        <property type="protein sequence ID" value="KAJ3199133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUB7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012875">
        <property type="entry name" value="SDHF4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524:SF3">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07896">
        <property type="entry name" value="DUF1674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3199133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="86" mass="9783" checksum="E32B99D9B6B02239" modified="2024-05-29" version="1">MEDLIKSKQKELETSDYHPDAQSENTGPQFEGDKNPVTGEIGGPQGLEPTRYGDWERKGRGITERLLEGLLCKEEFKDCDDKVLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUS3</accession>
    <name>A0AAD5XUS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001650">
        <property type="protein sequence ID" value="KAJ3201927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUS3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="82" mass="9106" checksum="57B92F6D63959FC9" modified="2024-05-29" version="1" fragment="single">MKLKKPQIIYTTFGKLLSSDDQLLDYFNSTQDAALNISEGESFLGKDLTLKANCDEVFIPCTQKVLANKSFVDTEAVAQLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVG7</accession>
    <name>A0AAD5XVG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AMP-activated serine/threonine-protein kinase regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SNF4</name>
        <name evidence="4" type="ORF">HK099_004660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000336">
        <property type="protein sequence ID" value="KAJ3219518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVG7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042856">
        <property type="entry name" value="RSP14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15599:SF1">
        <property type="entry name" value="RADIAL SPOKE HEAD 14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15599">
        <property type="entry name" value="RTDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="HEAT" evidence="1">
        <location>
            <begin position="255"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="439"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="571"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3219518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="625" mass="70333" checksum="A45A6A7D7F76DA09" modified="2024-05-29" version="1">MTLVKNPNLKFVNLDGFQPKECTEILSNTVPEINENFSQLAYGRRAVPKLVSEVESDDLALKTHAIINLVELFHNPEFISQGLEEDIVPKLTKLLKNSNLTIKQKTTECLSTISGYALGRTALIEENTLLNLSKAFDDEDPLVRKNAHLTFARVTSQQAGVDNILPWGSIPILVNKLPTERVDIQCIILDCLYNCIRMGPKPWIPDDPLKCDAMGVFTDLINPSAVTQVKVGTAKCIMMLSFNPEGKKRAVSGKTVPILIDSLTDLKSEVRAAVAGALMSITIDVDAKRLIVRENAIPTLMRLLDDKNESVLLNVIKTITNCAEDYRGRFQLHGCIKKVSRKIKIMEIVSKIKSTLKTQTCYDTLPQSYKLIVFDNKLLIKKALAALLLHVRIFLQSLVTDFIHLILFYYNESTLENDVEDIEHLQIFRLKELLKQNDLIPTLKVSIHPMDSLYEASKLLLKHKLHRLPLLDVSPDGQEMLLSVLTQHKILRQIALNVEDCIYLDFTPKSVGIGTYGNIATAELTTPLVDLLNTLVEKRLSSLPILDSKARENSYYDLGMPVSECLNRRSYDFEGIHRCHLSNTLGNVMDTIKDKLVHRFVVVDDNDFLLGVISLSDVLTFFTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVK5</accession>
    <name>A0AAD5XVK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001775">
        <property type="protein sequence ID" value="KAJ3201142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVK5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3201142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="438" mass="50119" checksum="92FCB2F87C705664" modified="2024-05-29" version="1" fragment="single">LSKISSHRNSLYPEELTNEKFTSYLVSIGVAESNWDQALHHPTILDKNIFNPPSLKKKKVSKLDLTDDKISIIERHSKLFSDQASIKRSLSLTKNTLYLKEESRLKNNLPLHRKESNTSDSTEYAISSHTLRSQSSDTCVPSPNGTLHASKDFLLPFEKDPIYGSLSRSSMKTSLSRSAFSLDRPNNSEFQLQRKLSNSSFGKLNKDDTSQSLGRPSRFTVTKQNTSPRPKRVFTVEKCSLNNGRTEIEVMNKEVKKLEEVEEKSLEDLEKFNYFTFPQGKKNLADEEDFFKTNSLVFVDREEEEDVDEKLLEVSNNNNNNRNSQIVLGKKKRLSRIIKFDLKSIKSDKSNEYPENGIKPISNNLSMEKKLDLENNVEMNQFSITSLNNLKKKELNFGLILGSTITSRTSGRNFKVERINSGIEVEKGRFTIKKKKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWG4</accession>
    <name>A0AAD5XWG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS19</name>
        <name evidence="4" type="ORF">HK099_007281</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000696">
        <property type="protein sequence ID" value="KAJ3213585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWG4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000118">
        <property type="entry name" value="40S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001266">
        <property type="entry name" value="Ribosomal_eS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018277">
        <property type="entry name" value="Ribosomal_eS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01090">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01413">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00628">
        <property type="entry name" value="RIBOSOMAL_S19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="143" mass="15962" checksum="D9CD9CAFC99C5299" modified="2024-05-29" version="1">MPGVTVKDVNSHAFVKAYAAYLKRTGKLDVPKWVDIVKTGTAKELAPLDSDWFYMRVAALARRVYVRPETGVGAYKKVYGSRVNRGSRPHHHRAASGSVIRKALQALEKIKVVEKHPDGGRRITQTGQKDLDRIAAQILKKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWJ3</accession>
    <name>A0AAD5XWJ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_003016</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000204">
        <property type="protein sequence ID" value="KAJ3221870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWJ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000388">
        <property type="entry name" value="Putative RING zinc finger domain superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051653">
        <property type="entry name" value="E3_ligase_sorting_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168:SF1">
        <property type="entry name" value="OS02G0798600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47168">
        <property type="entry name" value="RING ZINC FINGER DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="291"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3221870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="374" mass="43157" checksum="7AFD5FCD41B31FC9" modified="2024-05-29" version="1">MFARRKDASYLRGDEFTLTWTTIRQILQTNLSTMDQKDKKNQISQLTFNLKPTDLDKLTKKIVEFVTSHWEFEYNKRCDVDIMNFVLKCWEEILTISFLFSYLLIDRQAAFGPILKAPLNGTLMFMYKGCKVNFTKERPSDFIALVERGDCSFVDKVRAMQNTGAIAVIVGDNTNSVALITMYASDESTSDIFIPSVFIAKWELISLREWIYENITYISLVPNELDLPLFQVILITIITPVIVLSIFYLLWFYRDYISKRKEMASVEEVSNLPCKVFDGRVQSENFQAQGCAICLDDFAVGDHLRILLCNHEFHIHCVDRWLTKRKRTCPICKKSTIKDAVNSTSIEEANTRNISFLSEITPLLNNDNINSTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWT0</accession>
    <name>A0AAD5XWT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001576">
        <property type="protein sequence ID" value="KAJ3202401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWT0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="369" mass="41900" checksum="47B4E4CB80CF1955" modified="2024-05-29" version="1">MFYKSYICLALFSTTFQSAIKRDSSVDINSKNLNQIKRSPLVTLQVVDVQLQRTLSLAEATVQVTETVNYATTKEAFIEAHKTERFIEATIKPLITQQQKPAYTTLYAVDIQTEAYHHRTTQGLTGDTDYANEDSKDDTDNASTDSKNDKEQKDETEDPEDKVQNSAPNDATFETVTTQQLKPDVVPTAGDQKPLETTKTKTEATPKFGAKKKITEKEPKTEEKPLESSISVQEENSSAAVYFILSFVIVCLGVLYWQERRKIQKKKKESRMTSRFPVREFDRTTSRPHYDPLNDIDGHTFDPYRDNDEVASRDHSVNDELVPTRPTNPFLTSDEASQSSFLNNENIWVTFENGDLAASDSRFDTFGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX28</accession>
    <name>A0AAD5XX28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mRNA guanylyltransferase</fullName>
            <ecNumber evidence="4">2.7.7.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">DNAH1_2</name>
        <name evidence="22" type="ORF">HK099_001757</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.50" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000153">
        <property type="protein sequence ID" value="KAJ3222905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013846">
        <property type="entry name" value="mRNA_cap_enzyme_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF36">
        <property type="entry name" value="DYNEIN HEAVY CHAIN, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF17852"/>
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        <source>
            <dbReference type="Pfam" id="PF17857"/>
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        <source>
            <dbReference type="Pfam" id="PF18199"/>
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        <source>
            <dbReference type="EMBL" id="KAJ3222905.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
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    </evidence>
    <sequence length="6138" mass="705896" checksum="994168C690170098" modified="2024-05-29" version="1">[encoded data, 6138 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX49</accession>
    <name>A0AAD5XX49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="8">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">S6K</name>
        <name evidence="16" type="ORF">HK099_001397</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
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            <dbReference type="ChEBI" id="CHEBI:29999"/>
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            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
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            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
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            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
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        <property type="entry name" value="AGC-kinase_C"/>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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        <property type="entry name" value="Pkinase_C"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
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        <property type="entry name" value="Protein_kinase_ATP_BS"/>
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        <property type="entry name" value="Ser/Thr_kinase_AS"/>
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        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
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        <property type="entry name" value="S_TK_X"/>
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    </dbReference>
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        <property type="entry name" value="S_TKc"/>
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    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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        <property type="entry name" value="AGC_KINASE_CTER"/>
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        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
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        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="54"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="465"/>
            <end position="763"/>
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    </feature>
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        <location>
            <begin position="764"/>
            <end position="895"/>
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    </feature>
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        <location>
            <begin position="1"/>
            <end position="40"/>
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    </feature>
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        <location>
            <begin position="30"/>
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        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="83"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="499"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00049299"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00051693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3223209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="905" mass="101257" checksum="B0C0BF46FCA61603" modified="2024-05-29" version="1">MSESLSTPTPTPPKKKAPGLKVSMPVGTLQKKSSALNDSNVSKSNKMKLKDKDLEFICELGAGAGGTVTKVLHKPTGTIMARKVVGVAVDGEHEREQTEKKILRELKILRLCESPYTVEFYGAFAHGGDISICMEYIDIGSFDHILGKVGCIPEDIVAKITVSVLKGLMYLYDEKNIVHRDIKPSNILINSVGQVKIADFGVSKELVNGTIAKTFTGTQGYLAPERIAEGRKHSIESDIWSVGLTMMELATGRFPFPPEGQAPLPSVLDLLRYIEEEPALCLPPGRFSEIFEQFVSKCLIKDANLRPLPKVLLAEPFCVKAENDGLNLIEWAKEVKLKLETSESLRKNVFKEIVFTILYFPKKNLQVKKCLLFWLTRLCYISMESGNASEEEADSYEAIDEIFTLDVEEQVEDVAFKTTSPLRRNSSFKITVNSYNADETGFSLSNNATTTTPTLLKKSVGLKDFDFQYVIGKGAYGTTKIFKLLIPLLLLGKVFLVKKRNAQSYYAMKVLKKASLIVHQKDTEQYVSPLFLLCITFILSTLNERNILEAVQHPFIVKLFYAFQTSFKLYLILGYAPGGELFTYLHECKMFSEDQVVFYASELVLALEHLHSLGIIYRDLKPENVLLGEDGHILLTDFGLSKVAVNGARTICGTAEFMAPEIINLDLYLENVKNNKAVPNEPPSYDAAIDFWGLGAMMFDMLTGSPPFTGGNNKKVMENILKKKLFIPNYLTPNSKDILNKLLKKHPKARLQDWKLLKNSNFFKKMNFKNLLAKQIHPPFLPTIQSLDDVSNFSKDFTSMSLNTPPESNTFCSCIATASEEDNVNLQLEKINNSEIDNKAINEKLNFISDKNDCSASNSISSPLNLHLKRCGKNCAVNHFNGFSFVNENFLVDSIVDHLHSDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXH7</accession>
    <name>A0AAD5XXH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclin-D1-binding protein 1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000743">
        <property type="protein sequence ID" value="KAJ3213128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXH7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.10">
        <property type="entry name" value="Talin, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026907">
        <property type="entry name" value="GCIP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049317">
        <property type="entry name" value="GCIP-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492">
        <property type="entry name" value="CYCLIN D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15492:SF1">
        <property type="entry name" value="CYCLIN-D1-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13324">
        <property type="entry name" value="GCIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-D1-binding protein 1-like N-terminal" evidence="1">
        <location>
            <begin position="47"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="375" mass="42619" checksum="DC1E39CD120F4540" modified="2024-05-29" version="1">MELEETITKPLKKLINDLLMNLDILDLLSESQQQTDLNLNELELRKELVSVGKVISHNVTRLSLSASNKSKETENICKELSKILTYLVSIIGGLPNSTGDFVLKDLKVATCGILFDVSSLANSLLKESIQTVDERFRSSNFLIQTGIVWESAKIFEEIPLNARDSSCKKINATIELVTDAILEVCLKICTLFILNPLKVEEGLNNGGVGGDWEVDEDDVQEEEEFSEFERKIATKILILLKSSKLLMTKIIKVITNVDLSEIMLKKFSEMSIKEDGINLLRDKNNSDIFEDLSSYCQNISYKIDDSCCLLEAKFDKEELKLNLIQFWDAVGATFRVMKNESFYLEEKNWFELCESNFKKNFELVFSDLLISSVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY37</accession>
    <name>A0AAD5XY37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sm-like protein lsm7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LSM7</name>
        <name evidence="11" type="ORF">HK099_004662</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000336">
        <property type="protein sequence ID" value="KAJ3219520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY37"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01729">
        <property type="entry name" value="LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017132">
        <property type="entry name" value="Lsm7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF5">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037188">
        <property type="entry name" value="U6_snRNA_Lsm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="34"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3219520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="128" mass="14162" checksum="31B145ACBF2CB080" modified="2024-05-29" version="1">MDQKDNKKSQNAKRGGRGGGRGGGRGGLHSQKKEAILDLAKYLNKKINVKFSGGREVVGVLKGYDPLQNLVLDECEEFLKIRDEENNTTQEESSRKLGLIVCRSTAIILLCPIDGMEEIDNPFVQKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY56</accession>
    <name>A0AAD5XY56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTP:AMP phosphotransferase ak3, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AK3</name>
        <name evidence="6" type="ORF">HK099_004567</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000326">
        <property type="protein sequence ID" value="KAJ3219804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY56"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="5">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="184" mass="21474" checksum="5E999EADDB6ACE98" modified="2024-05-29" version="1">MNTWCELVNDDLAVRVVFEELKKFSKENWLLDGFPRTLGQAKKLDESLNEVNHPLDLVLNLDVPEDIILKRIVDRYIHPASGRTYNLNFNPPRRHGFDDLTGEKLVKREDDDIKIVKKRIRTYHLSTEPLLDYYRQKGVLKNFVGKTSAEIFPKLEKVLIDYNSKILIYYDKTQKAAGKPTILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY61</accession>
    <name>A0AAD5XY61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000827">
        <property type="protein sequence ID" value="KAJ3211566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY61"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="130" mass="15372" checksum="F1099424A2907D93" modified="2024-05-29" version="1">MTTNIESLIFEVSRLSYFNSNVIYKLRNDKKDIIKSDTDEFKILIPWMNLTGYSANVYDKNDKEVLKLTQNYLNTTINMESEKGKIEVKQSDWNNLSDKLFNYKNKSYAWKHVDHNNIKLITLPEEELIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYE6</accession>
    <name>A0AAD5XYE6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nonribosomal peptide synthetase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NRPS4_2</name>
        <name evidence="10" type="ORF">HK099_004111</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000282">
        <property type="protein sequence ID" value="KAJ3220662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012728">
        <property type="entry name" value="Pls/PosA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02353">
        <property type="entry name" value="NRPS_term_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="901"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="949"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1145"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1187"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1403"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1441"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="793"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1713"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1718"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1749" mass="196165" checksum="BCFC976156788112" modified="2024-05-29" version="1" fragment="single">NDDESLSVVIDHHFDVGQNHLTSKASLKSKTRSVYSRSSTLRSTKTSLARLKKDVQLLGALVSLPYSIAAFVLLLRRSLPDIPNFKLDIWIISHGKEVYGGKIVVPVLENSLFIELLSVINNQLNDVQLHDVNIYYSTLFLEWNEESDNKVNRYPLSLPNIDKNFLRFELSGFHENAKWKDVQIYSRKGAFANQTSESPLPAVKSHFYQICSQFEDAYPTIIDLLEVRDIEVLSREERELLHFEFSNLSSFDKVDLIDGKQPYLATIFAAVARRFPNRPALVIGDDVLTYAQLLKVSQTVAAILINDFGVRPNTTVALMLSRERATAFYSMLGVLFAGAAYVPIDDLKCPVDRAAFILEDAECKVAIVENQFKKELIGGKTAILSSDDMLDAICTTKRIFKEEMVKRSPGDAAYIIYTSGTTGKPKGVLVMQYNIANLILVENRMFGLNQYDRVYQNFSHSFDFSLEEIWMAYAAGAALVAPTQEMLIAGPDLPDLLEAAKITVLNLVPTHLSILARDVEGLVMICLGGEAAQENVIQRFRRPGRRIWNTYGPTEVTCSATYLEVSQPVEKMTIGKGIQNYSTYIVDPTSGVLLPNGGMGELILGGHGVASGYVGRPELTAEKFYPNPYPQAMPHWNNIARYPTNAVLYKTGDLVKFTPTGELEYFGRIDCQVKLRGFRVELGEIETVLCDCDNINTAIVHVWTDEDNGQTIQTLCAYVVLDDPSIVFSENEVKEKIAEKLATYMIPSIFVILSANEVPRLPSGKVNRKMLIKPEISLEENDEDFDGDIEEIQTDNKIQADIYLIWKKVFSSAVSVGLDSNFFKDLGGHSLLAARTISTMRENPALAKVGVKDLYKYPTIRSLAHFINPDNDNTVKVVIEDSDGMIKRFNNLPHRTPEQSYWICSLFQFLSFYPILLVASFPLLGGTLVPLELLDDVLPYFPETWPWEVAFFLLALVGYTGARIVQVLFCVLIKHIVMFGRYRTGIFPIYGSYYFRWWFVSNLMGTVKLADFHGTPLLNLFYKFFGCTIGKHVHIHSSTLDCMDLLTIEDGASICEGAIILGYEMKSGWIRFAKTHIGKNVTVGTHSVVSPGTILEDDSTLGDFSHAPIGSRIPQGETWSGSPATKVMDSRAELSEIYKVSGFKYFCYCVALFFGWIVMYIYNLLLIGPFFVTGYILIKFNPFALGWLWPIIIAFPASTFGVILFCFMGVLLKICTVGKMKPVHVPLISFYYIKKWMFDSMFNGALVGMHTLFATLYLPPWLRMMGAKIAPYTELSFFSPMNCEMMELDEGCFVADGVVTCAPKMSRGMMTTGGLKVGYKSFVGNQSVVPPNTVIESGCLLGVDSVPPYIKGEYKIKDGQTWIGNPPVEIPARDVNTEFEGSATYHPSNLQISGRLLLITQEYFRIVVPIVITNLIAFGEFLFLVIEEDENFPLNWWLKTLAFPILVGFYFLLEALIIISMKWILMGKYTNSRAPLYSSWVRRTELCTGIQEQVAGATFMPLMKGTFLASLFFRLMGAKVGKKVYWDSFDVTEHDLVEIDDEAIIGPNVTLQTHLFEDRVMKCGPVKIGARTNIGTRVTILYDTSIGEDTDIGPLSLVMKGEQISANSNWAGLPADSVTIRTRKFITNPLLQRKQFVVDILHPGRPNVSKKDLRDKLAKLYKTDAENIFAFGFRTQFGGGKSTGFALIYDSLDAAKKFEPKYRLQRHGLVPEAIKISSKQRKERKNRGKKFRGTKKAKAAKDAKKKGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYX2</accession>
    <name>A0AAD5XYX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000219">
        <property type="protein sequence ID" value="KAJ3221619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYX2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="344" mass="40635" checksum="A326AC38129B2E7B" modified="2024-05-29" version="1">MAFKKGLINGHFGVSQDVIYALSLFNLTYTQIVDPRRFAPYGHSKKYADYLNNVERLGDYFCDNFETVIVGDTIPDSRFLLQRLDEETYRGKCHIKKLILFTTARFDYGLNIKDDTEDYYKLLKNLMLNENTSNRIFWFANNPWEIKYAKIKLDSDILNFRLVRSFGVSNFKLRNITKEDSEMPVLISYPNTREFEFLLKKNFDFKLLSKNAYGGGVNLAQYKCLIQIPYQVSTMKMYENLRAGVITIIPSKRYLKFLMNVPSYELSAVKDSFEKEGQSFDYIDYYSKELNNFFYEFDTLEELKAMVSKSKEELDYKNVRLNGPLYWKIVNLESERSWKNVLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYY4</accession>
    <name>A0AAD5XYY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fido domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000423">
        <property type="protein sequence ID" value="KAJ3217511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="entry name" value="Fido-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504:SF38">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="Fic-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="143"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="229"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for autoinhibition of adenylyltransferase activity" evidence="3">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="303" mass="35229" checksum="256247DFCC3AED0E" modified="2024-05-29" version="1">MLLVSILDYDEWFNSKYEDIYSDKDIDLIKSGPLFQRYSNLFIDQYHVNDLRNSEINKLKDSVNKLRPLNDTLVQHIEDKLGVILNHSSNVIEGMNITLNQTEKILANKTLSGIKTQDVLDVIGHQRAFNEIINIYRKVNDVITIEQICLINKYVMLNEDRNTGRLRNETNSIVKIGGRKILLPHPQEVPELMKNLIDWLNNININEYNICDLIVNFHIRFITIHPFSDGNGRTARLLCSLISMRHGYGILIISDTKREQYFESIAKWEDDKNFNVFGNLIVDELITCLKIYSKCLRSKCVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ11</accession>
    <name>A0AAD5XZ11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock factor protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HSF2</name>
        <name evidence="10" type="ORF">HK099_006543</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000570">
        <property type="protein sequence ID" value="KAJ3215088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ11"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="266"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="422"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="422"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="570" mass="64715" checksum="C933C3134BF03B15" modified="2024-05-29" version="1">MNETSPNLELPATVTLFISKLYGLLTNPEFADYLEWNEEGDVFHVFNTELFAQYVLPKFFSTQNFASFQRQLNIYGFKVVANVKKSQHVRNREAGVFWHPKFLRGRKDLLPEIRRKVTQKKKPSQIKTKTLNTNNVNTINEISSPLSSLLSPINGIPITNNDQNNNQSSLDTSNNLMHHNDLLMPLPRKNFNQANQIQNDENSPFAFNFNTNNNEHIAENFNSNNVHFSQLDQSQPRPIPYPSSISITRQTPPASPDMIGYMSNLSVQQHQHQQHQNSHPSPINITSPPLTGSYDSRRSNPIPIIGSISSSFNENRRSALIDRRSSYLSTVVGSPRYDISPDPAFENPSSSYTNSFSSFNIPNPNNNQSSHSIPTTSSEEFLNYFEILNRPQQQQQLQNTGHPSPFHTQNSQQVNFNQSQANNINNINTNNSNNIYSRQQQSGNSLSNQSFYPSTRQIHQQQNQQYSQQQSQPFYTYAPQTYTPPPQSFTPPLNGNSDQILSLFEVPKPKFHYTPTSLGGADNQNPAFNFYSQQNTKNTNTAARNNFATNISSNLNSFQSSLFTNSFPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ52</accession>
    <name>A0AAD5XZ52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase II subunit RPB3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPB3</name>
        <name evidence="8" type="ORF">HK099_000062</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ52"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07031">
        <property type="entry name" value="RNAP_II_RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="271" mass="29879" checksum="E5BC4FDB6ABD3C4C" modified="2024-05-29" version="1">MNTGGPEVRISNISPEDDIIEFSISGVDLSIANSIRRTMIAEVPTMAIDLVEFENNTSVLTDEFIAHRLGMIPLLSTEVSSIDYTRDCNCNQYCTKCSVQLHLSVSAKDANKIVTSADLISSHDSIVPASNNVTIVKLRKGQEVKLRCVAKKGVAKEHAKWSPVAGVAFEYDPHNKLRHTNYWYEKDIKKEWPESKYAKEELEPGLTDAYDCKAKPETFYLTSEGTGAMEPRDVVVTALSTLLAKLGLASVLLKNIASATEGNEDNHNSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0Y4</accession>
    <name>A0AAD5Y0Y4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">B9 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">B9D2</name>
        <name evidence="7" type="ORF">HK099_002135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000169">
        <property type="protein sequence ID" value="KAJ3222581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0Y4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010796">
        <property type="entry name" value="C2_B9-type_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968">
        <property type="entry name" value="B9 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968:SF2">
        <property type="entry name" value="B9 DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07162">
        <property type="entry name" value="B9-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51381">
        <property type="entry name" value="C2_B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="173" mass="19748" checksum="E3303AE5D2A15BA6" modified="2024-05-29" version="1">MAELHIVGTLIGASQFPASELCCEDWKLLEGFESAQTQVDIPAEDSNITLWDHPIDVHYSTNSIEGWPKMQFQVYHQDSFGRNELYGYGVCYVPTIPGTHEIDCVTWRPVGSFTDQLWSFFLNATPQLKNLDIIHNPTDRYQLTTESMGKIHLEITVICRNFQNYGVCLSTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1B4</accession>
    <name>A0AAD5Y1B4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004316</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000030">
        <property type="protein sequence ID" value="KAJ3226706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1B4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041898684" description="C2H2-type domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="760"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="786"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="787"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="850" mass="95468" checksum="EE1FD06AF33FBA33" modified="2024-05-29" version="1">MHLTTISLAVLSVATVQSKGVYFALYDEPTTVAETKPQQTTLAPYKGDDKPAATLVPTTAAPAPYKTPSNLVEQYDEDCEDEEDEEEECEEEEEDDEECEEEEEDDEECEEEEEEEDCEEEETYPTQSIVPVKSTTYPTATPAPEDCDDEEPYPTQSIVPVKSTTYPTATPAPEDCDDEEPYPTQSVVPVKSTTYPTATPAPVEEECEEEEEDEEECEEEEEEEEECEDEEVEEDCEEEETKDLKDEEDCEEETETYPTATAKPVESTKPTENAKYGANPKYAPSYSGKAAAATKEKEGANLNDKSVESHSSAMKSAGTVIALIVAVAVFCTMDPSNLFHQHFANNLPRNSYSKTSPNPTVSNNNNFIPSFETKNLLSPVSPTNTTYVQQENIKNNNSSPSVSNYNEIENYFMNTTSLDQIQVDLFSHSLNLSSPDVHLHLNSPTTQSPIDVDKFEANRLSILQVTEEYRNIAAQFSSSDQIIPTPSTPPVSISNSNLKTNNLNYFPEQLSSPFPFPRENSPFLRPESSYSLTAIDYTTTEFNSITPIPISNENTDFKSCEQVQQSGSYFSMDSGNSMRSNSQTDYEMDYQNQHPSQQNSFHSIQFSSSSNNNNSNNNNDTNNNTKANKNEMDSNFFHQPVPKKKIMTPDFTNEFSIPFSISPKQISQITNSELKRPKSTPAVNSLTTDSVKYRCKNYPYCTKDLKTLNGMKYHNDVSKKCEFEIGKNEEINLINNKISTELKNLLKSKNIKIIEKKYSCKKPNCNNIYKSYNGLKYHRLNEHNEIDSSNSDTANTTNKATNSNNLNKTSVTNNNHPNNFNILNHSPISPPLTPIISAYPRSFRSASSMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1J1</accession>
    <name>A0AAD5Y1J1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Exp1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EXP1</name>
        <name evidence="5" type="ORF">HK099_002187</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000170">
        <property type="protein sequence ID" value="KAJ3222555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1J1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="84"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="195"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="84"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="195"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="289"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="375" mass="42329" checksum="233B70773114013B" modified="2024-05-29" version="1">MSKTPVLKNLQIMIRLNFPVIGTCTAPFIRSRSYVAAATTSSSSPSSKRKLNQNSEFLLTYQNAVVVILRRQLKSLDKPTTVRPKRPPTAFLLYLQDVRPKIVENLKKTNGDTTNKVLFSETAKKASMSWKALEKSEVERYNKLSLSKRKAFEKDFKNYLENRSPQDVYLEKIKFQIAKKLGKRVAKPLTDVNAPKKPLSAYVSFVQRLRDNENLQVELTGSKFTGLPQKEIFQRIGKAWRSLPAQEKQKYEARYESEVRAYREKLNNYKEQHGVKDFIESQSKSLAQIAKPKPKRKARRVAKKKAAPKRKVAKKVAKKPVKKAGAKVAAKKNTKPALKKAGTKAVKKVASSKAAPKKKSAAAKKVVSTKSKKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1W4</accession>
    <name>A0AAD5Y1W4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cilia- and flagella-associated protein 418</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007846</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May be involved in photoreceptor outer segment disk morphogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Photoreceptor inner segment</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1W4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029239">
        <property type="entry name" value="CFAP418"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33958:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33958">
        <property type="entry name" value="PROTEIN C8ORF37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14996">
        <property type="entry name" value="RMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00026215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="21822" checksum="160927CFA6BE51F1" modified="2024-05-29" version="1">MPTEEDIDKLLDEFEVLSIKKETVSFSDCRYEGSIPLLRQRNSAPSVNHNKPYIIPKIIVNSKESDSIVPNLDDLLDEFEVSESVKGSSNKNFSIKKKIETLKSEIDEIKIKQKCIPPILGPLLKNTSNLKSPCENLFCLKCDLNVIKFGDKFWCRNESTGADLEYLFFRNNFPDLEKLQVGLVIAASVHGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2K6</accession>
    <name>A0AAD5Y2K6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cilia- and flagella-associated protein 69 ARM repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2K6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902093">
        <property type="term" value="P:positive regulation of flagellated sperm motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048732">
        <property type="entry name" value="CFA69"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048733">
        <property type="entry name" value="CFA69_ARM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14716">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14716:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21049">
        <property type="entry name" value="CFA69_ARM_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cilia- and flagella-associated protein 69 ARM repeats" evidence="1">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="106" mass="12220" checksum="A0255E7039461596" modified="2024-05-29" version="1">MKASVQSNNMEFEGFCINEITLNLRAKVYSLFCKLGFENFYSTLSNVERVKLELISKYLDFKISEVWEEISEELYVEGIRPTTPDLNSIKESGVIVNEKALQVTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3P5</accession>
    <name>A0AAD5Y3P5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="132"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="215" mass="24612" checksum="C5316F1C2C16E508" modified="2024-05-29" version="1">MALVNSTIEYPFPSALNDALAAYIYLTETKSSLFIEESEEQKKTIYSPEDKPPAKAVLMSPWLDLSGKSSSWTRNAKTCFLPQTVSDLTSKVIYSEDSPQHPSLMYIFGSHKYNKICSYTELEKRLEHLKVLVDHPLISPINSKFNNFPKTLLQVGGGEALLDDSMEFAKKYNSANRGNLLKLEVFENMFHDFQLFFWLEQSDKAFKSIKNFLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y424</accession>
    <name>A0AAD5Y424_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">OB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y424"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="32958" checksum="F5309F9E25025CCB" modified="2024-05-29" version="1">MIICSPNQFSTNYLFISQIKRLEKHEILKEYFYLNKKHLIKFVQVVGLIVEAEEKTNFILYNIDDGSCTIRIVQWLRQSEVTSRKFEYLKLGSLILDDPNQEFMHWLKAIDISQNDYCKNGSEFFLTEELEKEIIEVNENKKEEITNQFVDLNREDSNFSKVEFEKKVNSYLSANDVDPEQLKDLFEYYFKNGIIYQKEVDDEKELDEYSLITVTLKKDIFKLIELESGISFDQLLVKLKFQRKYFHLSKSTLRECLQCLINGSDIIEVNKNAYKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y432</accession>
    <name>A0AAD5Y432_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007302</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y432"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="218" mass="25329" checksum="04FA396F43F93098" modified="2024-05-29" version="1">MFTLYQSQQDLLNSSNPNNNKPYISLRRFAQEDPISKLHLLISHLNFNYNSVSDFITKDGLILYKNNKNCLHTETEHPGRGPIPLSRVNANANRNAFVLQHRPEDLLPTVYHDTYEDELEVEDGFEEGEEESSDADMVGESAFALAPRDYLEDIRKIEYEKMNVNSKREIEEFYFEAVEFARNKGYYQDLENIDSNVNVTYNAMDTEDHARISFDVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y499</accession>
    <name>A0AAD5Y499_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GSG2</name>
        <name evidence="10" type="ORF">HK099_002889</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y499"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072354">
        <property type="term" value="F:histone H3T3 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024604">
        <property type="entry name" value="GSG2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419">
        <property type="entry name" value="INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24419:SF18">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HASPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12330">
        <property type="entry name" value="Haspin_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01331">
        <property type="entry name" value="DUF3635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine/threonine-protein kinase haspin C-terminal" evidence="9">
        <location>
            <begin position="752"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3228384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="894" mass="105056" checksum="43A43DBB0ECFA413" modified="2024-05-29" version="1">MRKTYGKSVRKKLITSFQLPNRCNQLNSIKEVEKFVEFLNLEKTKIEKIIYIQKTFKNNKLARDERKIFLNKIEKIKTIQAFIKKFLHQRNFKKIKFSVKTIQYYYRSHLIKLKYKKTRHSIIFIQQFWRSYTIQKKIKYHNVVTDDCSVIKIELRKNNDLMDFDNLWCEGTVENHFKEIDAEDGFLTSVSSKINSRCEIDLLTLVTGSDNYVECETISEKVQIFETPENFEEDFFSETSQNSSFEKRTTGCNTADFLSPLDLDFGKENSSEIKDIDAVLNVSLESDLIFKLNFNEEDSKPAKTVDNNVDAKLPSDMKRNCALVLNDSSVRFNSNSEQSTPNYSTIEEKKNHMDIELTAFNFSPTTQFLKSKNSLTGLFESESLIENKLARLEGKKSKNLLVSDERRNSSAKEVFCKEKVQKKVLKNSNKFVKQGGVTFYDFREYKYPQSELLDENIKNFKNLTLDSKENVPMAVTQKETGTKETIEYAHLRNHLNLNNLCTTSTVGNFSKYFDNSRFSSIVKIGEATSSEVFLVTDKEKKKSVIKILPFDGAMEVNGYRQPNINEVYQELVITSVTGNHLFKKFGFINFVKLHKSLIVKGKYPKKLLQEWDKYDVKHTSENDRPDYFKSTQKFILFEMEFGGEDLEEFSFFRGINEFKSFFFQTCFSLSLAEHELKFEHRDLHWGNILIEKTSEDYLTYKIPIFNCNNKSKKPTFKSLKLKTYGIKVRIIDFNLSRLETGSNLYKMDLDDPDLYNQDIESKTDIQFQCYRDQLTLTKGKWGNFFPQTNLIWLNYLLTKCWEFKFKKNLKKKFALEFNSFHKKFSIEKLLHTSLKDENFFFKSSIDVCKDEFFYDIFVTDDMLRDEGEDSMDLDNNNAKDNNEKFFSHLILSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSR0</accession>
    <name>A0AAD5TSR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003269</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002167">
        <property type="protein sequence ID" value="KAJ3199194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSR0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051999">
        <property type="term" value="P:mannosyl-inositol phosphorylceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051706">
        <property type="entry name" value="Glycosyltransferase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385:SF15">
        <property type="entry name" value="INOSITOL PHOSPHOCERAMIDE MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32385">
        <property type="entry name" value="MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="205" mass="23710" checksum="A687C0E566E0115F" modified="2024-05-29" version="1" fragment="single">CQEINDDFEYKLWTDDNINEVFMYNKEYYDSWYQVKKAGAADILRIDILYQFGGIYVDVDTVCLKKFDQALLAEQFFAGYESLNNSLSNSPNSQLIANGVLGSIKSHPLLDLMRQNIKSKDLSETKSAWKTVGPALLTRSYHLFLKFTWNRDWSVKVRPFSDFYPYHHSEGKTIPQTTDELNSTLSKHNQMNSFTFALWGGTLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT67</accession>
    <name>A0AAD5TT67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002576</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001867">
        <property type="protein sequence ID" value="KAJ3200619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT67"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="402"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3200619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="455" mass="51379" checksum="5212D11303FFC48D" modified="2024-05-29" version="1" fragment="single">MSLDLLDFSNHFSQLGSKFQSQFISQFHDTELDLNKPNNDHSNNDSYHQFNDFDYLNFDDLISCNSDDKPSSSDLDSILNDFSSDSIDTNNDDNTNDNLSDNNLDSLYSSDLLFEDLKSNLDLDFSPHLNQSTITSPSEHITFALLNNNLSTKNIFRSNYINHTSILSSSPPPTNFISDLNQSNPVNSNNQKDILKKEPVTKLAIKIPSKKTINDFSFPQQPTPPYSPNNSSLFNNLYSPTNSIYSPNPLQSSSAAVPYFTTSNFNATSPFPSPTQERRFSFASSTASLPCSQSLQVLPLIPLPRKRKAIAQILISPEQQVMVDLLLQPNYTKNRINKKEKNFPCPCGKQFERLCGLKSHIKVHQSKKQSLGINEVSKNLEWTEENGSPISLVDEAETSRNFLCDSCPKRFLRKQDLRRHYQCTHSDSTKALKCPICTASFSRSDALHRHVQANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT89</accession>
    <name>A0AAD5TT89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PEX3</name>
        <name evidence="2" type="ORF">HK099_002142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001691">
        <property type="protein sequence ID" value="KAJ3201661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT89"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006966">
        <property type="entry name" value="Peroxin-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28080:SF1">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04882">
        <property type="entry name" value="Peroxin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="427" mass="49319" checksum="2C036DBDD34A6C37" modified="2024-05-29" version="1">MSSIYNFLLSQRRKLFIVTGFAAAVWGLGKYAQTKLLEINTEIDLQRTAKANVKRRFQQNQQDCTFTILSLLPTLSDNILTNQNVELLIYELQQKKNSNEKNNDKLHKYKQWEELKLMSKTITSLYLVTFLILFTNTQLNLLGRYIYLDSISSIHNKYDPDGDNNFTGNDGDYNNNDDKDSNQNSLQICEGSKKCISTETERKFLTFTWFLLNKGWKRVSDMVERSVQKVMGEMTIKNLTTFESFLDILKGIRTDIEEAPEFILHQILLPEEGEEKEVLKEGLTNISENDPKITVDEELKGLLDETRDLFESDDFNMVAKECLHNIFKKFEQNVETLYYPDLETTKENIKSQVTNLDEKEEIDGKKFQTGVIYETKSLELPIAKLIPSVSKVCHSILNGCPNEYVEAVASQSDLKTFSVIIYTGWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTE5</accession>
    <name>A0AAD5TTE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH-ubiquinone oxidoreductase B15 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001765">
        <property type="protein sequence ID" value="KAJ3201216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTE5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="11383" checksum="B62FDD2CC0512FD5" modified="2024-05-29" version="1">MFFLRKYSSGKSKYPALLIDPAIEKWYHMKENTHAYFKFNRRTITYSVMLTLVVPGLIFLGCYKWHHALDFTGLGRGESPLVAEQRKRRLLERSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUW7</accession>
    <name>A0AAD5TUW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002020">
        <property type="protein sequence ID" value="KAJ3199868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUW7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="120" mass="13743" checksum="F9A4EA0718EBE595" modified="2024-05-29" version="1" fragment="single">MTQISNTNNYNPLNFSVNYISTYLLNTLQQFAKNLVLARLKNIKFGRLKLIVINKKVEPINSALDSLQEDVFCFGDFSTDENASPPEVVKVLDLNFFLRLILFQTLGFGESFMNKEIEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV83</accession>
    <name>A0AAD5TV83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001076">
        <property type="protein sequence ID" value="KAJ3207153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV83"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="152" mass="16928" checksum="4C514C864EF9BF05" modified="2024-05-29" version="1" fragment="single">YDVSVKLSNYAKFYFELRNLQEIEKKIKRVTKPLNLKEVYRLEAKLLTNVEGSNTRGEASSSQSAVKSEAIQEVAMKIMESGNNNTLAPLLYSKTTLDQAVNAATSIGRSSALHGQHIQSKDATDAIKADRLFRRSNSDYIFVSTKPPANIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV85</accession>
    <name>A0AAD5TV85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000954">
        <property type="protein sequence ID" value="KAJ3209191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV85"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3209191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="277" mass="31363" checksum="DEB884361DFA53E9" modified="2024-05-29" version="1" fragment="single">MSIKLVDCYYSSSKSLLCGVLDLTCLNLTVNKLLSISLTLQGISLVCISDSHNEIYDTQKQLTFLLEYPLKVPDNIKDQVLLPFNISITKPMLPSISKEAAFRCGVIGEGSSELSVNYFLTAKVVLHELNNKSTEDVITTTEKIIINGKNRQDVKMCLNNQSFTLKNKADSLLRLNKKIFFPGEKVVLNVNIRNLKKLLKSSLKSFKSFKIKLIQECFLTLSSFEENVRYGRCNIFKLEERNLIKNNIEQIEIRLPESGNALPSGEMNNAWKGLIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVI5</accession>
    <name>A0AAD5TVI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000882">
        <property type="protein sequence ID" value="KAJ3210584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVI5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="38743" checksum="3F48ACBAF59A100A" modified="2024-05-29" version="1">MLTNILSNLSPKINRSCQNATGTVFDKNYNNAQEQYHYHDYNLEKGVDNHEFIANKYSNNLSLNVSKSLIKNNRKVIPNLRIHTEYDKYTPEVLSAPAAMDDGTYFNSTHHQFPLKRSNSTGGPIEYNTLLSNTFSREGNWRHLPRPFAYTKKPLPSLTRTRSLIEHNLPSHNRQPRSQHYSNNRQESGYPAYVAEPEAVLDTNSTTHPESVSFHEEMLKKNNYERDFDDLELLKSQVAKSTIILKNLQSSGEYIENLIKERYQERNFSFSSEINTALKNLNLKLSNLEEKTSNNQIEKEILKKKNEKMKNDLKQVLDEIVKRLTNLEETVFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVL6</accession>
    <name>A0AAD5TVL6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleolar protein 12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NOP12</name>
        <name evidence="10" type="ORF">HK099_008571</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-25S rRNA processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRM RBM34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000959">
        <property type="protein sequence ID" value="KAJ3209115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVL6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12395">
        <property type="entry name" value="RRM2_RBM34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034221">
        <property type="entry name" value="RBM34_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF25">
        <property type="entry name" value="RNA-BINDING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="305"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="50"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="407"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3209115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="437" mass="49833" checksum="A5F8547E83359D5E" modified="2024-05-29" version="1">MFKTLKLDSKLNELFEKSAGKSFLLNKDILVDTVANEELKSKNELVIKKVNSKKPNQKLNTEKTYESPSSSKETLNAKDNDAIKEETKKKKRKFRQCDESSNKDQEKEIKPKKLKTETAVNNSDQDNSVAKKKEKKKFSNREKEPLVVKQEDVELTEKNKRTIFVGNVSINIKQSSILKKFKKLFTENCVPKEKDDFSENPSEKNLSNTSVDTLEINNKKKTSPLESIRFRSISFSRNVPIEMRKIAFRNKEFHDSRDTLNAYIVFKDSKFASEALKVNGMVFENKHLRVDLVGTNQKKARLPKQCIFIGNISFDETEEEIRRFFSDCGDIDNVRLIRDSKTNLGKGFGYVQFSDKSSVDLALKLQGKPIGERNIRIERCDKKLSNKINSAEYSGAKSIKGVQLRLSKKSKKGGNSGIKSKGKGAAILKPKKNKPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWA9</accession>
    <name>A0AAD5TWA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001627">
        <property type="protein sequence ID" value="KAJ3202070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="286" mass="31941" checksum="77B2536FABA2309D" modified="2024-05-29" version="1">MATNTTFVLYSLTTAALKPQAPILSFAWGVATLIAIQLTIRNLLNNRRSWIDVVQFLAGFSLIIQELISFFKTMYNLTAPVTPDCDYVSYTRFLSFILFQIFANVVLILRITVLVPKNFQLFVRIILGVLFATSIAITITATAMYIKPDSCARPLNIQLNGIGKMLASILYGLLLLCFIVPFKKIVKTAAAHNVQSKNLKEVSNRVLIQTSIPLLVYFFSAILRFSGLWGDYSNLGFILEDVSIFVCMSLTFSLRNNDNSSTQRGGSSGNNFSTNNYSNHQSHGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWT6</accession>
    <name>A0AAD5TWT6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000772">
        <property type="protein sequence ID" value="KAJ3212590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWT6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3212590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="549" mass="62632" checksum="A792CDB4247BCDBF" modified="2024-05-29" version="1" fragment="single">MTVNPISDHCVDYLSYNFDLFDLHTSWKYSTRHKDSITNGRRLENASWRKFYQMKNKLQQIHPSELNWQKESDVVWLYGPFHTYDPLPILEAQYAATKTNFSKNSEKSIINKTTDINNNNNNTSTDNLKPVLKKRSDQDDFLQTLREIYLENKSLKGRKANNKFENETSNIDNSDSDLSPTTLMLSIQRVESKTKVYQKNNSLRSRDDASDSPSDRPFFYSNSKSLPQIYKHGKRLENTGCAPDTIQLTLENLDAKSPSTMKQIRFKKNVEKRLYVGEDDVSSLNEQSQKFSQPRKKSLGKKSISPSNSSSNLLELIVNSSNEGVGHSIEDFQDAMEYTDSTKEEFNEMSTKKNLSEILKISYKIDNPTGKGVKLNFLLDDSDDSDDEASTSEDENNSENEVNFQVLPKGVDKELWEKIIPMRNVTRSDSTKSLNALGNRHYSNSNSNLIALQKFEKNNNGIPRSASPSPMSPTLKYNIPDIPRHKFPPGITTPKQLDEYYANLYHDSDGNDSDENESYTRRFIDVGANAIELGGWLTKSAVRSVGGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX65</accession>
    <name>A0AAD5TX65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000652">
        <property type="protein sequence ID" value="KAJ3214072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX65"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="236" mass="26917" checksum="2A4263E1DE16A45E" modified="2024-05-29" version="1">MSQQPTITTTQQRPAHLGTTSTSYVPNDSSIDRNLNSRISKEFIVFLILFTISFITSIVAFNAPDFLVTRKDPIFGISRSFGLFETCIKKGDDFSCYPFPGDKCRLPDRPDEEFTSCQTWLTARYLYIFAIVFGVLSMIGWFLSIFNYLRPKILLATAFTTTFFVGFQIVVMVLLVRLREDNTFFNVFGRYGSSFNLLTVGWVLGAVIILIFGVLAMVKRSVYDDLRNDPMGYLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX70</accession>
    <name>A0AAD5TX70_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP-activated protein kinase glycogen-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003083</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002076">
        <property type="protein sequence ID" value="KAJ3199608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX70"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-activated protein kinase glycogen-binding" evidence="4">
        <location>
            <begin position="18"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3199608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="322" mass="36037" checksum="310EAD2E3BEB7C68" modified="2024-05-29" version="1">MLKFKTEELISFVDPLDNATKVVITGNFDNWSKSVEMEKKGNIFLKNITVEIGTKLVFKFIINDEIWTTSDTYEVETDEFGNSNNILIAKEKVGVENCGEIGGDISVKTQGMNLNVSSPINFIETEEKVPGFIRMDDALNPEISAANHKEVVDNLPEKIQNGTSKEKSSTSALQAQINEDRKTANNEILEDESVTAPMEEVTASREHNVIKELKEFSLNEAVEGLKISQENQTSQADTSRLLEIDNSATLNKKKEEMETSVKNELQNPKKSGLKKSVSFKQVANEKKEESDILLPFTKYSRYLIYASAALIAVCINFYSNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX83</accession>
    <name>A0AAD5TX83_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannosyl-oligosaccharide 1,2-alpha-mannosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001244">
        <property type="protein sequence ID" value="KAJ3204995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX83"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9711" checksum="FA7D147174A876C7" modified="2024-05-29" version="1" fragment="single">PDYIFNSEEYVFNTEAHPFPVWNKINKIKFKNFEIKKDSDSFPFNDYPGDDVDQVFQGFKKKICFFQDWLTAKSRTFPKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXC5</accession>
    <name>A0AAD5TXC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001081">
        <property type="protein sequence ID" value="KAJ3207081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXC5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="207" mass="24598" checksum="067339A7CAF81943" modified="2024-05-29" version="1">MIPPISVFIQQVFEIMKLSDIPIRDTWKHNGDSSTPKFNLDGFAKNNGYNGPFCCDYNWTHLDSFAEFQFGSEDEVSQFYYIHNFESLAYDSYHLNISTEYLYDLHLSYSPIARELVHLLQSIPSKLEVKEFLINQKSSGDEQLTRLELEAYFVQALYIMKYEKSRFFNALKKKGYHSDLNYYDKFKYYNDADARELLVLFRYHNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXF3</accession>
    <name>A0AAD5TXF3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008398</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000917">
        <property type="protein sequence ID" value="KAJ3209912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXF3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035493">
        <property type="term" value="P:SNARE complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3209912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="217" mass="25214" checksum="D0AE807877543EEE" modified="2024-05-29" version="1">MCSVFCLDYNREKFNAAVGYIVHMTTMLSGYLGVRLPFEMHRIFLPKIDISSEFSFPDQSFPLYLTDHNLKEFIFGISMLNFNILVLCFSQGVRNIKLRESCFTLENLARCCQAVELGRDQNVPYAIEKESKNEKNVEKNSNDVKDQDNDFIEAGIGLKKNFTIDFKKLLQLQNELKLFKTDVVELGKTKVLEKLDMLCTAIELSFEEKEEEWQFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXK9</accession>
    <name>A0AAD5TXK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Cysteine proteinase 1, mitochondrial</fullName>
            <ecNumber evidence="2 9">3.4.22.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_000139</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.</text>
    </comment>
    <comment type="function">
        <text evidence="7">The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.</text>
            <dbReference type="EC" id="3.4.22.40"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.40" evidence="2 9"/>
    <dbReference type="EMBL" id="JADGJW010001016">
        <property type="protein sequence ID" value="KAJ3208045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXK9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070005">
        <property type="term" value="F:cysteine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043418">
        <property type="term" value="P:homocysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00585">
        <property type="entry name" value="Peptidase_C1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004134">
        <property type="entry name" value="Peptidase_C1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10363">
        <property type="entry name" value="BLEOMYCIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10363:SF2">
        <property type="entry name" value="BLEOMYCIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03051">
        <property type="entry name" value="Peptidase_C1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005700">
        <property type="entry name" value="PepC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0788">Thiol protease</keyword>
    <feature type="active site" evidence="10">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005700-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3208045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="493" mass="56724" checksum="7A01C9D076356F47" modified="2024-05-29" version="1">MFLTCSSIPFACKIFKKNKNQKSTVEVPYSTTELPPKYKEKVDGDKSFLHPEIIEKSITQSAIDSFSKHYNSNPKNELAQTVIKQAKMETVLLNNDALIRNEREFEIKIKLEGNVTNQKQSGRCWIFASTNTIRLGVMKRFHLKEFELSQNFIFFYDKLEKANSFLQKAIDLADKNETSNAVQELFSDPMQDGGTWNTVASLVEKYGICPKSAFPETYHSENSTEMDWLLTNKIREYGVTLRRLIHAGEKSPEEILQVKAKMMNAMYRIIVTCLGEPPKSFDWKFRCTKGHFHSFENLTPKSFYEEHIKKDVIDKVNLTHDPRHKFFKKKEEDGTIYGTKEYNVNVPIEVLKEAVIVQLKNNDPATFACDVHKFYGKNTMDMDLFNYEAAFDLTPTAMSRLDRVTYKESYANHEMVFTGVHLDSDQKPLRWRVENSWGAVLETTGRHAGGNGAGGFEVMNDAWFNEYVFDVVIDKKYLSEGNLLKVANAIQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXL1</accession>
    <name>A0AAD5TXL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002517</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001839">
        <property type="protein sequence ID" value="KAJ3200778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXL1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17325">
        <property type="entry name" value="MFS_MdtG_SLC18_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF23">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3200778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="294" mass="31744" checksum="2027377A9C1B09BA" modified="2024-05-29" version="1" fragment="single">MLIGMLGLAVATVLFAYGQNFLQLLLARMGQGVAGGVSWTIGLCMIADIYPSHQLGEVMSRVLSFNTLGFLVGPPIGGLLFTYFSAETPYLFCAALALIDLFARLFIKPSKIKKEHLAEEVDVTTALLDESNNNSQTQNNLVLKKPASIIQLMKDPQLIVTCMIVLIGATIFSGIEPTLPIFLETKFFLEPNLIGVIFCCIIVPNMISSLIFGKLSDKFGRKNISFIGLILNGLAAPLVGYSFDLPSLIIFLGLFGITTAIIMTPTLAEMAEIVERLGGGANASVYALYNVSYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXX9</accession>
    <name>A0AAD5TXX9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000592">
        <property type="protein sequence ID" value="KAJ3214784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXX9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041910487" evidence="3">
        <location>
            <begin position="22"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3214784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="556" mass="62865" checksum="1997C1B3049BEE2F" modified="2024-05-29" version="1">MLKPLIHLIFLLHLISSQIESFQCNTNNDCTIQQPFCSQGLCQSQSQIDSVSKSELRSCSDSLPCSGSSNICYENTCYSYIQLINIPWIAIALSCTLIFLLVIFPVLTCFLGKCLCFSLKDPENSKSNDESSSPADIEKLKQQHLNRERQQNDFVDNVEAEKDFLKKRDQLVEKIITGDSSVIFEETPMSPERVLPHSTLQSVPLHQQPNYTTPSEIFSEVEEKKPKKSKKELKLEQELFLLEQERILDQSRNEEYRQDEILMQKKKALLQQQLLQQQHQSTTPYPIQTILPTYYVAPSHPSPLSNHQFIPQFQENLHPHTGLSPHAYPHSPSPQSPQLLSQPMCSPPQQYYSMQQQQLPLTNSIHNSSQHSIVYSQSNSPSIPFSALNRNSSQHSLVYSQHAPSLPLSALDRNSSQRSVVYSQHSVHSGYAPSNTSSYMRKKFANELSNNYLQPQSIPQQHPIQSVSVEMPTLQQSPDINSNLHFRQDSGAVTTSSIASTKLNEPTSDFSKLNFSHDDKKVLSSPTFSTANNNETETSKVDEAKADVSNRVETEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY57</accession>
    <name>A0AAD5TY57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000601">
        <property type="protein sequence ID" value="KAJ3214661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY57"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041930000" evidence="1">
        <location>
            <begin position="19"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="64" mass="6802" checksum="C21546CCE826C591" modified="2024-05-29" version="1" fragment="single">MNFLKPASLLLLLSTAFAAPGASTGVENQYIVKLKSEVSALSGDVLDSHLSWLDEVLSKHSDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY78</accession>
    <name>A0AAD5TY78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cis-Golgi t-SNARE syntaxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SED5</name>
        <name evidence="10" type="ORF">HK099_008100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000857">
        <property type="protein sequence ID" value="KAJ3211073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY78"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021538">
        <property type="entry name" value="Syntaxin-5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11416">
        <property type="entry name" value="Syntaxin-5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="222"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="146"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3211073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="274" mass="31280" checksum="BF4A2230CED5F96B" modified="2024-05-29" version="1">MQDRTNEFNSILQSLNTQGQHQQLLNSNRQNLKKSEFTKASYQIGKEIQQTLTKLNKLTVLAKKKTLFDDKPVEINELVFVIKQDISKINKLIMQLSQYQSQQLQKESKLVQSKEHEVNVINSLQTKLQQTSQTFKSILEIRTENMKEQKERRDQYSFGSSQQSMLLSQPPSDSPLYNPNQPAQQNQNETVLDFGEFGLTKRGKGGQQQLELMQTNSSAVNDEIINSRDSAIDSIESTIAELGQIYQNFAVLLQGQREAVMRIDQNVEGKGVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYE6</accession>
    <name>A0AAD5TYE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001484</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001419">
        <property type="protein sequence ID" value="KAJ3203504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYE6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042265617" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="27"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="6">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="289"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="298"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3203504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="638" mass="69290" checksum="AF50DCEC30137845" modified="2024-05-29" version="1">MKFFELILYTTLAISASGLTLPSTCGQNKIRKEWRELTTDEKTNYVNAVKALKALPSTMNQGNKYEDFAYIHDLHKNTIHSVASFLPWHRLFLKDFENELQKIDPSVNLPYWQWSVDSQAPENSPILGPGPLQFGTGFGTGGACVTDGFVANWKKNDNSCLLRGTGDGAGQDGKLGAFYSGEHIASIVKLSTFDNFWNTLEGSPHALPHLAIGGDMAGMASPHDPIFYLHHTYIDKIWADWQKLGNGRYSEYSKIENKNKKLSYYQNTVSSVLDHRNLCYEYSYGVLPDGTPPTSKVTPPATTTTTTTTTETTSTEVSTTTAITTTTEATSSTATTGATTTQTTTSEQTTTGSITTSTVGTESTSSTTSSVSTASSSISSESSQSSETPQSSATTEVTTSSQSTEATTSVIIKTTTIIIPDSTSIVTISQTSSTTLPTETNSGSVTTTNTETVQTTYVVIPGTTYVTYYTETIPVSSTVSASSVTTSSTPVPTGTYGSYKVDPEDRTNPYYIRVPAPLPLYWIEMNKLNVDYVRTCEAVLADVAYNTNAQVDSDNYYPHSCLEAVKKEVYIPAQTYSEVNVDFTYPVDLSSTPLNVDQPTSPLYVAYKDENKSTDGQSSALRTFAYSGFIATIFFLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYL3</accession>
    <name>A0AAD5TYL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxysterol-binding protein- protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">OSBPL8_2</name>
        <name evidence="2" type="ORF">HK099_008558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000953">
        <property type="protein sequence ID" value="KAJ3209219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYL3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="261" mass="30115" checksum="A294DB2FD9BE47BD" modified="2024-05-29" version="1" fragment="single">HKLKSPINPILSETFSCHYDNIKFHSELLSTNPTVSGIYISNEDHSVNFQHINDSKFGLGKGGFNFIIKDYGLCKMTVLGDVFRIELPSISVQPTSSFIFNSTTELYPVGEMVIKCEEVEASIKFQPKSFMKSYSTKISGEIKSKGEVKYIIEGDWKNEMYIENYHTKKKNLVALGNICPISNPDYPLRTIIDESTGSDKVWEKVISLMQIKNYKEAQKLKSRLEHWQKCYVEDLKKQGQEHEAKYFEKINGNWEFKNNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ06</accession>
    <name>A0AAD5TZ06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ATG22</name>
        <name evidence="8" type="ORF">HK099_005526</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ATG22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000434">
        <property type="protein sequence ID" value="KAJ3217296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ06"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032974">
        <property type="term" value="P:amino acid transmembrane export from vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3217296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="390" mass="43364" checksum="F61D94FE4DE42098" modified="2024-05-29" version="1">MPDFKALDSGWFKPGTCVDGQPELPLSDQDYYPRCVLPWGDGYIRSTSWTLNGISISVGVQAFFYISLGALADHGNLRKKLMMLFTWLGVLCCLLLAIPFPKELYWLPAILSIGVSLCLGSASVFYNSYLPIITEATPELIEYKKIESDSIKIEEKAESISNYYSIYASGLGMLGVAVLFAQVELKADRITIALLVILSPLFAFVGNHLFLFIQRKVHARAKTMLQVCLFGYILISIYGILGLTSLPVGFKPVNMLLLNDKCVLNTNSEGQQYYDGEGCKKIAWELYVFAVFHGLLLGPLNSFSRVIFSELIPTGSESEFFSFYAITDKGTSWIGPLIVGALNNGGGTLRYSFLYFLISFAVPIPILYFLNLHKGKEDAIKFAKLNEVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZA3</accession>
    <name>A0AAD5TZA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL13</name>
        <name evidence="5" type="ORF">HK099_005543</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000437">
        <property type="protein sequence ID" value="KAJ3217226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZA3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00499">
        <property type="entry name" value="Ribosomal_eL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001380">
        <property type="entry name" value="Ribosomal_eL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018256">
        <property type="entry name" value="Ribosomal_eL13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01294">
        <property type="entry name" value="Ribosomal_L13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01104">
        <property type="entry name" value="RIBOSOMAL_L13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="206" mass="23924" checksum="919D46EF783D8534" modified="2024-05-29" version="1">MKHNQLLPNQHFRKDWQTRVKTWFNQPGRKLRRRQNRQKKASLIAPRPLDGLLRPAVRCQTVKYNTKVRKGRGFTLEELKTAGVRRKEARSIGISVDHRRKNRSEESLSLNVQRLKEYQSKLILFPKNVKKPKKADSSQSELSSATQLKGTVLPIKQDKVAFSTGKVTNNKVHAYATLRKAQSDARYKGVREIRAKAKEEEEKQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZM1</accession>
    <name>A0AAD5TZM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DUSP10</name>
        <name evidence="7" type="ORF">HK099_004926</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000364">
        <property type="protein sequence ID" value="KAJ3218820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZM1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="243"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="306"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3218820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="460" mass="53403" checksum="48DDD8E02328D93D" modified="2024-05-29" version="1">MPSIMVDLNDIDDGDKLPTSLPIPESCNSDEMFQIIKNEYLNTLFLDLTFNLAHGHLPGSYTNSLIDLDCVSQNDVYLKRRIDRKVVVFDEEGSVNGWAYQCCQILLLENKVESCCYLKGGLRNFNYKYGYLTKTNLEEKCSAQLQNNPNLEFEWVNVNEKILKGEKDQEFISKLDDTDENKENKLMDKEYAALNKKEIELINSDYNINFENGSVSPVYLLKLQQKHLVNSVWYGKRAPYGDLPIMILPHLFLGSSQTASKELVKKYNIKHILRLGWGFIDECDVADGIIYHDFPIEDTPSQKIEHLFVTTSKIIENARLKNERILVHCYAGVSRSSTIVLSYLINYHNLTLFESFKFVYLKRPIIRPNLGFTIALQRYELKKFKNLDAPTLDKFWICESFIHFLNFLDIEFRINLHTNEKNEKDSSLLTDENFEIKKISVSSVSDEFNKIIEKVNVNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U055</accession>
    <name>A0AAD5U055_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000572">
        <property type="protein sequence ID" value="KAJ3215060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U055"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="144" mass="16087" checksum="876D0E5F4D92D2BB" modified="2024-05-29" version="1" fragment="single">TLMLKDLVQECKVEQSALTKCMNKNLALCSSNMETVKADMLKLFALFEKLDNRLSEMEIDLSRMFSFGSETLGTKGKTAAMILLNDYNINTENFRLNSPNSLNNSNPLQPSQILPLTNNSDTSIHDKNAALSTNKNIIEENLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U057</accession>
    <name>A0AAD5U057_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004856</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000357">
        <property type="protein sequence ID" value="KAJ3218992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U057"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="4">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="381" mass="43624" checksum="4FCDC1648AEAAA3F" modified="2024-05-29" version="1" fragment="single">ELIRIHKVMNSEVHENAQFLPWHRQLLRDFEYEMELAIKTIEPNYRFALPYWDSTLDSQAPETSPLLQPNIFGNNGDQFNNYCLTTGPGERVRWGHWFPAHHDDNSCVQRYYGNDFGTPNVLGAFYPPGAIQNSLQTYSDNYWYFNREVQFGFHAKVHANLGGDMANVAISPNDPIFFLHHAFVDKVWNIFQNLKPENKNMYFGPAQGGAPINPNDPNDDPGFGNSFPTDLLSYFGIPVSSVFDTYAERLCYKYSNYGVVNSPQLKEAIAQTNGANNLSFDKDKEDEPLKKVETPDSVDRTEPNLLRDFGHISEDFILKMGWNLTEVRAVENRNLKVVKKLNILIANKKYDSPVKLGGKNLYKAVYSVMANNRFKKSKTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-11-27" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0B3</accession>
    <name>A0AAD5U0B3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005449</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NUP186/NUP192/NUP205 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000424">
        <property type="protein sequence ID" value="KAJ3217501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021827">
        <property type="entry name" value="Nup186/Nup192/Nup205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11894">
        <property type="entry name" value="Nup192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1423" mass="163582" checksum="9C31AEC458772F92" modified="2024-05-29" version="1" fragment="single">MSVEGDLGDFETDFDEFEFINLTLQLLEVALITNLSTFDLARRVKTLPRMLSNFSKNKTVASTDGLDFVNSRLNFLAENFNEEDQRLVFFKSTLLEQKLEFSICLFDLVSIDQVVFEKAVSKEVAFDEEFEFFKILNFFKGIDSSDIISPYLLLTLLKFISIDVLNQNIQQTQMHLFKLTKDSLKMLNNELFTNSENFSDTNLKAVLQFQFIIFFKHRQRFEYMDPFSFNSDPDYLEKQLEKLIFDHNIFNYFVLMVSSNNTSDLINIWKDVRVDFRCEIYSTLELLISHFIQNFGRSVRNTKKSDEDVVKKGYYERQRQYLNNKIVPPTKTFQTLLTLISVLYHDRPDAALQFWTSNELLKFLKWASDVKSLELKSTYFRMMASLATGPKSSHHAFELFNSQQTLSISAISWQQMFAALQHFSSTIYENPNLDINPQDIEVMIGFLNLLKTTVSYSPVARFYLFENQSTVAIQELFRLLVCRIPTNLKAALFEAITGFCTQCPGIDYLPGHSDIIANVWLLLEESQVLSEKDGIFSKDGIVFDLEETETVSQVFPETLAFLGLLNSLFSTSNFRHITSAVENLGEARRTPGIYPFIDFVIEFGFLKIFQRSYAKEEEKFRMTSICLEIFNSCVEYFFDSVLKIEFERAKFISTSSPQLHSFSETEENLFHSLSKFPGFKIVCNVLTGSTFTKILFDILKLVKQIDLQKGSSHFYFGNSILECLALIFRILKYQDTFLDKIVPKMIEITTFGGGKSTIFSNSMVGLDQLLAYHKDIVIILAQLLNCTSDDQIVLLATKILKIISCSNVFLKSDTDSMQCKQSRIVKLFQGNEVVINGFVNRLMNGEVKESMEVADSDLLSNLKYHGGIDLEISGIGNSVRISILDLLLENLLISNNSGIATFAHFLLGFDCTKFLQNTNFYDPNSKKNKAYLLHYIINLVSADTENSKSNNSLNFNKLHPTLSERCCHLLYKLCLNLSTYEPTLRYLRSTGDFILKQLAHISDDIKQEGIEVMVLEQENENLSLVKRNEISALHRKAWLMKLAAIDLHTNILSRKTSEIEKLFNCLFLNNNTFLFENFESNERKGSDQPLTKILEIFNSLNLKEDVSSDSPLDLGSLKFFRNIQFEHFVVKNDRGCEVFDIRLIFKYLSAIEYQLEADGIISSVQLKVEFQNELKDLLYNILRLNSSKEYYFAQKECLIGWNEIVLVALNEGYHYFPLQSREELMYKILSNILPRINNANTRTEFIEILSSTSLTLISKLNSDKFIQNILQAPSTNENFSGLLRLPLEGQLLVLEHFLEGVIRTGSTSKTRGNYYTSIISYLHLTSSTNGNHSIQNNSNIAVFEKFGDRFFELVCRDATDGPEVWKTVAFSLLSAVFSIYFEKSSTGKNSLLIFLSEKNHLDHFVKTIKLDDVNLQKVLRDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0P7</accession>
    <name>A0AAD5U0P7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000507">
        <property type="protein sequence ID" value="KAJ3215954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0P7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="19"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="107" mass="12551" checksum="CA7649AFFFA0AF44" modified="2024-05-29" version="1" fragment="single">IQKKSKEFEEFEEITESKNKLYNQEKLTHENDMKAAQIEIKSLKNRVAGLESELNERDDAHEEMVAKLLEGRKKRIARKPLTEKPFTQIESQENNLLENKINKLNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0W4</accession>
    <name>A0AAD5U0W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000302">
        <property type="protein sequence ID" value="KAJ3220449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0W4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="SER/THR-RICH PROTEIN T10 IN DGCR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985:SF8">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="307" mass="35411" checksum="26673C268FC8AFCD" modified="2024-05-29" version="1">MCISFFGIGLEKYKLVIAANRDEFIHRKALRAEKRDNFICGLDIGHIGTFGDEFEKSYGTWIGINLKGKFGFLTNLRQDIKSIQIDKKSRGFLVKDYISSEVEDLDPLKYLHSLNKKDYNGFNLIIGDLKKNKMYYTGNKGSLKLNEFDMRDTAIEKDLSNEGVAELQTNILYGISNGVLTEFFKEEVEWEKVKKGKTIFERLLKQDYKKEELVDKLLDELLSDNIEIHSNLPNILGIETEKNLSSICIECNKPGSLLKNYGTRTQTIILVDYADRLTFVERDRYTVDENSEIIPGDFRKIIEEVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U114</accession>
    <name>A0AAD5U114_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">beta-glucosidase</fullName>
            <ecNumber evidence="12">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_004009</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Glycan metabolism; cellulose degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000273">
        <property type="protein sequence ID" value="KAJ3220789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U114"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000002">
        <property type="entry name" value="Probable beta-glucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050288">
        <property type="entry name" value="Cellulose_deg_GH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715">
        <property type="entry name" value="BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42715:SF12">
        <property type="entry name" value="BETA-GLUCOSIDASE G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 12" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042110647" description="beta-glucosidase" evidence="13">
        <location>
            <begin position="17"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="14">
        <location>
            <begin position="665"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3220789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="733" mass="80477" checksum="64F5346B64147884" modified="2024-05-29" version="1" fragment="single">MFSLAKISIFILSVTATSWESATAKAKDVIKDLSNQEKVTLVSGIGWGQPNIWSGSQSNLCVGNIAKVSKINGFEGLCLQDGPSGVRFQNNQTASSFGASINVASTWDRELMHAHGKAQGQEFRDKGVNIALAPMMNIGRVAAGGRNWEGYGEDPFLASVSAAEVVKGLQSTGVMANAKHFLGNEQEHFRDAPGGWSKIDERAIHEIYLPPFKACIEAGVVSVMCAYNRLLTEDGELNFACEHKRALDGLLKGELNFQGFVMSDWWSTHDHILAANNGLDMMMAGEATNPFADKNSDLAWSHNLLKAVENGLVAQSRLDDMATRVLAAWYKVGQDKGFPKTNFDSWNNDRTDDKKSDQLINVRSNHADIIRRVGADSIVLLKNTDNLLPLKVNNKIISVIGDNSRPPKENNPNQFPDRSGVDGHCAIGWGSGTTNFPYLVSPLEALTSKANGTHTKFQYYSSTEKDYATIKDSDTALVFVYANSGEGYTGMNSTVNGPFVQGDRNDLFLFDYGDDLVKKIAEINKNVVVIITAPGPVDMSAWINHPNVKSVLFALYPGQESGNSIYDVLSGRINPSGKLPFTIAKENDYCCKVQFEAPGHVEYAESHLVGYRWFDSNKIAPQFPFGHGLSYTSFEYSNLAVSFNENGSGKITLDLKNSGNRLGREVVQVYVGLPEVTKSAPLNLKAFEKVRLSEQETKKVEFTLSQQDLSFWNVKSKSWELAKGTYQIFVGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1D7</accession>
    <name>A0AAD5U1D7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000390">
        <property type="protein sequence ID" value="KAJ3218217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1D7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="472"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="624" mass="69785" checksum="2EC92179D50DA59E" modified="2024-05-29" version="1">MQHSDPPNVLRAKFILGPLAIVLFFVFIGTEVKNYLSQLPILTLKINPNLQQVFVPTFCFSFPWGSIINQNQSPIQAFSVANPNVKLTDVFDISMRSFDNYFFLDNTKLKDLTIYLLVPKKPFVTYDVGFNVGYNLLDILPPGVNLTGLLAANGAVASIYTDIWIFGSRFSEKPTTGGTVNSFGIDPNLNATLFDPNFSPIKAYQNLTGGHIARDTNPFIRYGQFKSSTFSIGINSYTYINQSREVFYSTTFLGGSDNFGRNLFSSAPRTQLTFNLQNTQRTEYSESYPTASTAVMSSAMAAFQFLLITGFIVLFGRGKYSPYGLVHFLVPGTTIPTYKKDTRLTEDELNRDKINFFVAEYLDTTPMQQKLVTPTTPMPKKSVTHIIMNSISMACAGTALVLFACCIAGGNFGVSSSVNLDPYPVQNWWRVLNQEHFGLGFMLLALNVTLILVLIITKIGSTFMSILRTLELVVLPIMSIIIGANSIVALILFFYYYVNLQNYINSELINLSKLPNGSSTNTGNEVGSAQLGNLFWLLVLGTFFVLVLVVLTQILANSRFKMESEQKIAEDFAREQEDYNQFKKNSNNNQYQEVAKHGQEEGEEADENLVRRTWTKVSDNENVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1K4</accession>
    <name>A0AAD5U1K4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000426">
        <property type="protein sequence ID" value="KAJ3217470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1K4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042040688" description="Thioredoxin domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="266" mass="31541" checksum="1910EC56FD96A1DC" modified="2024-05-29" version="1">MRIFFYITLVFLFITTSSKETKEQKLERVQLAKEADLKIKIIEHSEVADFLKDGIKILFFGAKWCQHTQRFNPKFLAAYEKLEREGYSHRALGFFDMRKVECSEEQDFCEHVHKVTDGFPTTFLYKDGVLIEEYPYEDEVEPLVKYVKAQVDSYKSNLSHEQIKFHKSNANNFYNNKQLEEEELKKLIVEEDLNLNKEKSNHEVYEVDDTLEREDMILSSEELATLKELNEEDDQKNSNTYDYQKSKKNRAGYTKPNATFVKNYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1W4</accession>
    <name>A0AAD5U1W4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Chitin synthase</fullName>
            <ecNumber evidence="2 10">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CHS2_2</name>
        <name evidence="13" type="ORF">HK099_003573</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cell membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 10"/>
    <dbReference type="EMBL" id="JADGJW010000235">
        <property type="protein sequence ID" value="KAJ3221347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1W4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="12">
        <location>
            <begin position="79"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3221347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="328" mass="38309" checksum="5A3ECEAEBC028C1D" modified="2024-05-29" version="1">MSSHPNFTDHLQNSDEEANLGFQKYERGYLSTPRNTRFEYDKSSADDEEEEEDRSLLSPKHEKSFGTLKRGITTLARKAKTITLASSGNFIIKQKIPYQILDDAIFKNGEEFETLRYTACTTDPDRFVEKNYSLRVSNLKRNIEIFVVVTMYNEDENAFNRTLFALAQNIQYLCEKNKYGWDENSWQKVAICIVGDGRSKIHENVLKVLSVLGVYQDGIAQSAINKKETVSHIFEYTAQKIMDESRQIWSSKHKIPPLQLIFCLKEKNAKKINSHRWFFKAMCPLVNPKVCVLIGKLQYVHYLKFLLLRCWHKTREKRAVLFVESIFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Y5</accession>
    <name>A0AAD5U1Y5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">14-3-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004403</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000309">
        <property type="protein sequence ID" value="KAJ3220302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Y5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="8"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="261" mass="29369" checksum="4148F9D7721C70DC" modified="2024-05-29" version="1">MKIDPAPREDQVYMAKLAEQAERYDEMVAFMKEVAKLGVELTVEERNLLSVAYKNVIGARRASWRIVSSIEQKEENKGNDGQVSKIKSYRQKIESELGDVCSDILLVLDDHLIPAAEAGESKVFYYKMKGDYHRYLAEFAMGDKRKEAAGFAHDAYKAATDIAQTELAPTHPIRLGLALNFSVFYYEILNSPDRACHLAKQAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTTDLQDAEGDKAEDTKAPEEGEEGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Z3</accession>
    <name>A0AAD5U1Z3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS28A</name>
        <name evidence="4" type="ORF">HK099_003529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000230">
        <property type="protein sequence ID" value="KAJ3221435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Z3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000025">
        <property type="entry name" value="40S ribosomal protein S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_eS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="68" mass="7550" checksum="4478A944A84EE5EA" modified="2024-05-29" version="1">MDAKASAPKLARVVKVLGRTGSRGGVTQVRVEFMDEGSRSIIRNVKGPVRESDILTLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2V8</accession>
    <name>A0AAD5U2V8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein axonemal assembly factor 11-like CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005101</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the tilB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000385">
        <property type="protein sequence ID" value="KAJ3218347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2V8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000052">
        <property type="entry name" value="Leucine rich repeat containing 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056496">
        <property type="entry name" value="CS_DNAAF11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849">
        <property type="entry name" value="LEUCINE RICH REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23602">
        <property type="entry name" value="CS_DNAAF11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein axonemal assembly factor 11-like CS" evidence="10">
        <location>
            <begin position="224"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3218347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="643" mass="74238" checksum="47B0C2F34EEEE92A" modified="2024-05-29" version="1">MQKIDKELLKKRAEHNDGCLETLEEITLHQFDIEKIENLDIYCKKLKIILLQNNQIMKIENLSKLKSLTYLNLAINNIKLIENLEGCESLKKLDLTLNFIEDLTCVKNLKSNIFLEELFLVGNPCYQIEGYRNYVLGCLTNLKQLDSVEIERSDKIIANQEFLRLDEFFTENSIKIKEVESLAPKNENLQEDDDIILTEAEKEKKRESFQTKISKHTPEARLEQARDLQKLKKDKQEKKPDKKSVEPLPKPNEKVYQKNQLKFKYEFDNSSDILLKLKVTVPKQFETSMLKVDLEDKFVRITLKEKFLQLTFEHEIIKSKYTLERSILSGVLVLTMLKKGNEQYLNEDIKDLDLKLFKKKVNEPNVKENSKTDFKNKFSKNKRLEKFGFNSTNQEENSLNSVVDIKNIYKQKDENNLASEKKSCLGEIRNVKFLNSDLKVKIDDDFVDDPNVPPLSAPNASTIFIASMMAAAIGTSGISTALIQWVINPYVSKIHYNSDSDPNNPLITLETLTFFGNSIFTSVNAKDLEISQKRPFSVWKLKESIKIIESKAQNPAQGEIFQYAPNKKFGMLQFKRKYFYVHPSIMNNPETKDYGLLQNINVATGSKVTNPVLDALNNSELSTAGVKKNWNDLVDNLRDDLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Z2</accession>
    <name>A0AAD5U2Z2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Saccharopine dehydrogenase (NAD(+), L-glutamate-forming)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002048</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 1/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000165">
        <property type="protein sequence ID" value="KAJ3222643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Z2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004753">
        <property type="term" value="F:saccharopine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12189">
        <property type="entry name" value="LKR_SDH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000008">
        <property type="entry name" value="Alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000284">
        <property type="entry name" value="Lysine-ketoglutarate reductase/saccharopine dehydrogenase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000072">
        <property type="entry name" value="Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1870.10">
        <property type="entry name" value="Domain 3, Saccharopine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="9">
        <location>
            <begin position="16"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="8">
        <location>
            <begin position="194"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="940" mass="104997" checksum="19D116E81DB3ACCA" modified="2024-05-29" version="1">MHQLRLSAFSRSLSIGIRREGKNRWERRVPLIPIHVKRLVNEFGAKILIQPSTKRVFADKQYSEVGAIVKEDLSEADVIIGVKEVPPHELIPNKTYVYFSHTHKGQAHNMHMLKAVLDKKVKLIDYELITDDQNRRLVLFSRFAGYAGFMDMLHGLGQRLLSKGYGTPFLYNAMSFQYLSLPDARLDIARVGQLIKDNGLPRELGPLVFTFTGDGNVTQGAQHMFKCLPHEWVKPEKLKELIESDTWESDRVYGCQVLVEDYIKKKNSNEPVKRAHYYSNPEEYESIFHEKIAPYTSVLINGILWGPQFPRLLTNDQVNKLAREDNLRMISVADITCDINGSLEFMSHASTIDSPFFVYDPITRTESTTNMEADGIQIMSIDNLPTEMPIESSEYFSGAFCPFIVQLVKGNLDHPVLKRASITSSDGTLVDRFKHLYKEIEKHTPASSGFVVLQLITVTANSKNVLLLGSGFVAAPLVDYLLRDKSVHITIASNAKKEAEKLAQGKKNARVMPLDVGDQQNLSNLVKDHDVTVSFVPATMHTTVAEHCINHKKDMLTASYISPAMAALNESFEDVINTKKKTLRAKNAGITILNELGLDPGIDHLTAMKFFNSVEPGSRVNKFISWCGGLPAPENSDNPLGYKFSWSPRGVLLAGLNSGKFKKNNKLFDIPGSHLLKTSVDVPMFRGLALEGVPNRDSLHYTDIYGLGKLEDMDSMFRGTFRYKGYCELMAAFHDLGFFNVTEKSNIKSGTLSWPDLIKSVLNMKNLDNPAEVKAVIKESLTKEAIRTNIKDIPWTVTDALVERVHQAMSWLGMFKNSTPVVIGKGIPPTTLDAFCSLLQEKLVYEEGERDAVYMCHEFGVINKKGIQENYTSTLVAYGTPNGYSAMAKTVGLPAAMGVSMLLDGNIGGRGVIAPMTADIYEPLLVKLENEGIKFVEKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3R8</accession>
    <name>A0AAD5U3R8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000214">
        <property type="protein sequence ID" value="KAJ3221703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3R8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="146"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="201" mass="22809" checksum="CFDE7D9E1C2E4278" modified="2024-05-29" version="1" fragment="single">MKAIPHTPKSKYNSSTENSNSLQRDLSMLDSKISNLVTSENLDSKIDLEVDSLEYCFSSIAISDINKTSETKASHNNGSVNKRESFKKANSQLDDDGIEISRIASDDAGLRSGEKCLKSLKKIEKDSGVGPKINPKMEIYLPPHQKRKLMLEKELLRNDLDKKNKENFEKNKIKLEEKPNFKLEEKQNVIKVNKKVIENNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3V8</accession>
    <name>A0AAD5U3V8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NOG1</name>
        <name evidence="10" type="ORF">HK099_004233</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000294">
        <property type="protein sequence ID" value="KAJ3220526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3V8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1190:FF:000001">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000496">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="9">
        <location>
            <begin position="162"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="480"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="535"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="604" mass="69489" checksum="EF786F866DA6EF2C" modified="2024-05-29" version="1">MSRLIPTGPEFIDIVLSKIQRKTPTVIHPNYKISRIRAFYMRKCKFAQDCFDEKLGQILTDFPKLDEIHPFYADLMNVLYDRDHYKLALGQINTARHLIDNVAKDYTRLLKFADSLYRCKQLKRAALGRMATIMKRQKDSLQYLEQVRQHLARLPSIDPNTRTLLVCGYPNVGKSSFMNKLTRAEVEVQPYAFTTKSLFVGHMDYKYLRWQVIDTPGILDHPLEQRNTIEMQSVTAMAHLRCCILFFMDLSEQCGYSVAEQCKLYHSIKALFVNKPTMLVINKIDVMRPDQLNSADKALIDQIVVKDNIPMVQLSCFTEEGVMDVRNMACDTLLAARVEQKMKNTNKMGDVINKLHLTTPAKRDDKERPAFIPEGVKNKIKYDTKDPNRKKLEKDLEVENGGAGVYNVDLKKLYKLENDEWKYDIIPEIMDGKNVADFIDPDIEEKLAALEEEEERLISQGFYNSDSDLEMDTEVDIRSNVREPRPKKVLDKETRSRLESRMPRKRTRSVSQGVNIARSQSVGTQLINNPTLSKRAKTSMRSQTRDRSVMGLSSGQKEVSLGMKAKTDRKKNLLAKAGEADRTIQTKMPKHLFAGKRGFASDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Y2</accession>
    <name>A0AAD5U3Y2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase III subunit RPC8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA-directed RNA polymerase III subunit rpc8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">RNA polymerase III subunit C25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RPC25</name>
        <name evidence="11" type="ORF">HK099_000836</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Y2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000221">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013238">
        <property type="entry name" value="RNA_pol_III_Rbc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08292">
        <property type="entry name" value="RNA_pol_Rbc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="9">
        <location>
            <begin position="8"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III subunit Rpc25" evidence="10">
        <location>
            <begin position="85"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00077605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="218" mass="24657" checksum="5555EF12DF47967C" modified="2024-05-29" version="1">MFILTVLRDIVRVHPADLILPRAEAISNEINKKFANKVLHNVGLCIRVLDLIEVTDGVVHACQDGSYMSKGVDYMTLCFLPFLGEVLTGRVASSTPNGIRVTMDFFDDIVIPSDWVKEGSVFNSDEGVWVWKYDDGSENPAELFMDKGETIRFRVETENFEDIGPIKTKVLPSGDISTEDILVPYTLTCSIFEDGLGLVDWWRENIEEEEVDNMEEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4B4</accession>
    <name>A0AAD5U4B4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4B4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="144" mass="16613" checksum="384465A97AC6504B" modified="2024-05-29" version="1">MFSTTFEGAESAIRDVMYEYAKLLYDETIKTGVDHRSAEQAYTLMTELFKTDQKIRVVPVTLRSGRATKKQITTRKPKSDHTWLPYDEHFVYTVDWHLSSGYPLKFVNDKYITHTVNDEGTVTPIEEADVPKIIMQGYKPSIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4M7</accession>
    <name>A0AAD5U4M7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL31</name>
        <name evidence="4" type="ORF">HK099_004815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000351">
        <property type="protein sequence ID" value="KAJ3219121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4M7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.440.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3219121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="123" mass="14026" checksum="EEDECA60696C1902" modified="2024-05-29" version="1">MAKEGVKKSSKKTSALSEVITKEYTIHLHPKVFGQTFKKRAPTAIKVVRKFAQTQMKTSDVRLEPELNQALWAKGVKTVPHRIRVRLSRKRNDAEDAKEKLYTLVSYVPTKNFKGLTTVTVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6B7</accession>
    <name>A0AAD5U6B7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF2062 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000045">
        <property type="protein sequence ID" value="KAJ3226061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6B7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13443" checksum="7FB2902886A5D458" modified="2024-05-29" version="1">MSKPSLRVKPTPLVRKTRIPTKRKVQGFIKRKIITPFISALKGIKDVYTFKFSNFKLKDGIKPHELSLVIVLGIIFGLWPILGTGTPLSLFISWYLKLNIPIMQALHVIFTPFAIALGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Y5</accession>
    <name>A0AAD5U6Y5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chromosome transmission fidelity protein 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CHTF18</name>
        <name evidence="10" type="ORF">HK099_007026</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the activator 1 small subunits family. CTF18 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Y5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053016">
        <property type="entry name" value="CTF18-RFC_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46765">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46765:SF1">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="490"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3225291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1138" mass="130580" checksum="7BC337A45B6A859C" modified="2024-05-29" version="1">MGDFFEEELDVFDDDAMQAMMEMEEILHNENSVTPNNLNLPKRVGTYDSSELLTENLTLHKYHSDTNAFSFRGSCHSPSSRPCISQDPFPLISSQQQDEVQNRQNISIGGIMFEDSSDDEIENTSSNDEKSAKLMDFNTSNLIESKISIGGVSFVETDDDEGPQEYEGVKKFSGCISNKNFSKNEVVFMDDTEFNEAKAINLENETKKLTSSVLFEDSDNNYENFVFAKNLTPKKSFTEASLEINFHSMSPKMRSRKRSYEEQEFFISDRFKKKNEETLFSSKPSKFVKHQSSDEENANEDFTIEDKRAVKFAQNLSRQLHQNNFSSNNDFKLVKSKDFTVKPKDAIYYSVHMENGEKFYFPKIIKKKINFDRYTTNCSITESKNLNFGNIPNMIDTSLQDKTSEILLKENIQISGNPLRTTLWVNKYAPKQYIDLIGNESLNRKVLNWVKHWDQCSFGKKIKKKKIKTNKLMLTESDPYGRPFKKVVIDLIILLISGRAGLGKTTLAHVIGKHAGYNIVEINASDDRTGEVLKNKLQGALTNRNINNGKPNLIVIDEIDGASQTGGDQSFMKFLTDLVNNDGKTGSAAFDAAGIKKKMKRATRITRPIICICNDLYAPVLKTLRAIAEIVIIPSPAPLQALSKRLEEICKLEGLRTDIHSLMQLCLITDGDLRSCLNTLQFAYSKISTIEKKEKKKKRFDVDFIEKLDIGLKDMEKNFFFILEELFTLPINSKKNASVEHGKFIQRLFKLIISNDDIERLIQGIFENYLSSLNSNAMSNLFQISKSHSDSASSRIDAALDWLSFYDILDSKVNQNPSCFGLKVYLPYSLISFHHFFASSFKRNNLVYPKADYQNYLKRKNLENILNEFNSSMELKSKLLWGFNNSRELYNKAGSSQIKIFLEFIPYLLKIISPELKGYNLVLMNAKDKSAVKKLVDIMCSNGLMFVQEKQNLGVYDYKLQPPIEQLIEFSDFLTPKKTSSFFKKNPKIYNTALVKTGHQQTILRFSYGLKQILSLEIEKERLRRLDHFMEKKIKRNIEYEAHKQINGKESDETLDSAVNLKPRVTAPKIVTNIEPVKIESIKPLRDFFGRIIKIEEIIETDTEKSFKSEKLKNTVLYKYNEGFSNAVRKPVLIKDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U736</accession>
    <name>A0AAD5U736_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U736"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="190" mass="21947" checksum="72CC164CBAFB8F0F" modified="2024-05-29" version="1">MKYATFSSETSSINSVASKISSISSTPSNQNIKELCENVKKLYIADPKKKKLIVSKYYSNLCEFVDPLVKVKGRENLYAQFLALNFFNKVEVEILNIEPVVEVIKKAGDYETPELEFNIINKQSYYKTKNPFVLKTNTKLNLVFENSHWVVLKHKDTWIDHSKFDITPEFLKSLWGSFTSLLITSWFGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U788</accession>
    <name>A0AAD5U788_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription initiation factor TFIID subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TAF12_1</name>
        <name evidence="8" type="ORF">HK099_003512</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U788"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037794">
        <property type="entry name" value="TAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003228">
        <property type="entry name" value="TFIID_TAF12_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264:SF21">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03847">
        <property type="entry name" value="TFIID_20kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 12" evidence="7">
        <location>
            <begin position="128"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="263"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="299" mass="34392" checksum="B7B6226BA92A2C2A" modified="2024-05-29" version="1">MYNQAPEGSAEKIALGKSLERVNHQFAVWKQNIVQQNNLQQAQAQMQAQHLSQQSLMNQNKAQHFQNKAQFNPCPLFSKKLNLTPQQQNLIKLKTGQNQAPKSNQWNFLGDQSKIINNKIETLFKEETGDQADGAVKDVLLNMADNFIDQVMVFATQLCLHRMRESKNVLDVTDIQLALERNWNVRIPGFTDHLKIPKKFPQNQNYNNRSAALKKTIRESFSHVQAQKILKIQEDLKKCAEINNENKDLEKIELPIEDEKKIDDQIVELNSPSTLSPSHNKSSENFENGEDRPIKKQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7B8</accession>
    <name>A0AAD5U7B8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynein assembly factor with WDR repeat domains 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">WDR69</name>
        <name evidence="4" type="ORF">HK099_002928</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7B8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF744">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR WITH WD REPEATS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="65"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="107"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="150"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="193"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="235"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="277"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="326"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="408" mass="46196" checksum="D5E9D9AC95D0F3C1" modified="2024-05-29" version="1">MESKDINLFDLDEKTDVFDLTNKILLENSNLLKKKRFELICQLLTRLKEKISKINYEKFVLTKKIQAHSMPLTNCCLNKSGSRLITSSYDRTCKLFDTKTGELLHKYEGHQNVVSCLSFNNPFGDKIVTGSFDKTLKLWSTETGKLYHTFNGHHGEIICASFNGIQSNMLGSGSMDGQAILWDIRSGNDIWRLRGHSEEIVNLSFNNAGNIIATGSFDHTINLWDVRTGRTLHTLIGHRAEVTSVLFNFDSSLLLTGSMDGTAKIWDTSSGKCLSTLRDHTQEILDVTFSPSGNLIATCSSDSTCKIYTTKNNNFELKFNLKNERINNENTEISKVMFNGNENFLLTSSKSNIVKIWNCSDDFKNNTVPATIFQTLQDHEDEVFYSCFNYYGAKDNTCNIYNINSDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7F4</accession>
    <name>A0AAD5U7F4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Epoxide hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">EPHX1_2</name>
        <name evidence="8" type="ORF">HK099_002157</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000017">
        <property type="protein sequence ID" value="KAJ3227406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7F4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031567">
        <property type="entry name" value="CRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16978">
        <property type="entry name" value="CRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRIM" evidence="7">
        <location>
            <begin position="256"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="6">
        <location>
            <begin position="527"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="611"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="113"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="854" mass="97511" checksum="AA0D931EA1361FF4" modified="2024-05-29" version="1">MRTSFLKHSDDSVTKRIISLNETKEKDFLNIQKQLSFNNQTIDALNPPVNHSNHNQVFDSPEQIERNMENLREFQKLQEQKNKNSNTLQLPIVINKDQKNLLRKINASDNNLHKLAGETSTKRSKSSSLHEDSRDVKVEAGHHPEEGEENWENLEKSEFGGEVDAETNDDDNESNGGDSLQESIKVDLEEQEVIAKSMKEKEKEKEKILQYSTQKEKNSFEKNFVKIELPEAKRKEENRMSVAFLLKQQNAIFGKKSALTSLINDKGTENPFANEYGFFCGKGDADAIILKIYIPYSDEPSIPLKISVKRDAKVEECIGYALYEYFNEGRTPILEVDLCDIACWNMRIMDDDGTIDDDFPALERARKIGKFSFDQFALTTASPDQIKLNKKARQKESEMSITLPSSPSQPKVVEYLLRIHLYSTIEVKQTTTLKIDSSTLLSVVFEKICQKRKYDIKEYILKMADAVTDAPLDKTLEQLKVQEFCVLKRDRGGLGDIYLRPMDENNENQIVSSFQNEDKLGYKRTYQMSDQPSDVIWEQGMDKGYLLDICEYLESGFDLKKQLSLINQFNHFQEIIDDLEIHFIHQLSEKKNVQKPLMLIHGTNVIEYYSPLTNAGYSVVVPSLPGYGYSSIPKVTGCNTTKIAAIFNKLMKKLGYENYYAQGGDWGSFIARSLGHQFPINCSAIHVNMCFTPPPIYHVLEWPGIIAAKFVPKLFFSESEVAGMKGSEDYFLNGSGYFQIQSTKPQTLGYALTDSAIGLTAWISEKMLSWSGMRVSKDEILTNVLIYWFTKTITSSMRLYYEELKSGMLSVKYCSVPTGVTIFPEDILSTPQRWAKYHMNIQSWTNHNSGGLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7F6</accession>
    <name>A0AAD5U7F6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003346</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7F6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF26">
        <property type="entry name" value="OS04G0435100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="65349" checksum="0605CDAF44735943" modified="2024-05-29" version="1">MNSGTVQHSQQGPPSPVVSTTSTVIDESTALLNCSSVNILDADEMLLANMGYKQDLYRGFDAFMSFSFCFTTVGVISGLSGLFVYGMKTGGPSVLIWSWIIGGILNIIVALNLAEICSTYPSAGSVYHWAGCLSSEKNAPLYSYVTGWFNFLGNAAGDAFFAQSFSTMVNALYQLIYPENEPLSMEFQVFVAICSCCFCALQNITRIDRIGWLNNFATFWQVGTTGIIVATLFGTCSASGTTLSSPKEIFFTFYNGTGFDSKFYVAMIGMLTTLYSFTGYEAAGHMSEETKNTQTASPLAIAYTALAAMVVGLLYLIGLLSATASNVENFVLNQWEVTNIFGQCAGYTTGILLAILLTVNMYFSGMSSFTVSTRIAYSMARDGAFPLSKKIAYVSPTNQSPVGSVILVLSIDIILLLLNLVNETTFTAVTSIATIGYQISYAIPILLRVTTSKNVFELGKFNLGTLGIPMGWLSFIWLFCTSVLFLLPTQSPVTLSNMNYTGLILLLTFLIGGVAMSIFTAEIYEADLIALVLFTFAELEFFSDELSFVLLNVAQYCWTSFKLLYLLAKKEKTAKKKSSKLHSPVTQLSTVRLSTQNSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7G5</accession>
    <name>A0AAD5U7G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006269</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000053">
        <property type="protein sequence ID" value="KAJ3225769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7G5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="325" mass="37499" checksum="C468C716C6713566" modified="2024-05-29" version="1">MICPGCKKRSLKAFKYRESPRSWVKRFEKEHGLLRYKSEICQLPNGNARLWNREEVATLNIKSVVESYIGVLCIIGCGCFCVFYRNYARRKFYNLPTIKITLPSTSSLIDSFHQDDPEEGFLKVPPRNSKREKKDKTRRLTEDSILPPSQQKEGYDTDGLKEIDIDGSSGDLGEKIINSQEFEDYDEEAPNFDTEENVENENEENLKSLRDFKADSKKSLKSLIKVSHENFKNLFSSNSNTSVNNSNNININNQNGNNIIIQNVHTQKNENCQVNSIYDKEKSCSEILYKEKVIHPANSSLKYLNDESNKNGHFSFPRRKSQEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7K0</accession>
    <name>A0AAD5U7K0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">EF-hand domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">EFHC1</name>
        <name evidence="13" type="ORF">HK099_000257</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the calmodulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000105">
        <property type="protein sequence ID" value="KAJ3224099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7K0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000006">
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="719"/>
            <end position="754"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00004611"/>
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            <dbReference type="ARBA" id="ARBA00009763"/>
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        <source>
            <dbReference type="PROSITE" id="PS51336"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="763" mass="88276" checksum="537666F3501E1472" modified="2024-05-29" version="1">MDRLSIEEATGINIPFLPGNTFKEQSSDYRKPHSLGYKNGYPIQKLQLLGIGLEPIDINTQLLNTSADQLLQSLGSDPKLTYGDKRFHAKPITPRFVPAFVALDKVVLRFDAYFKETVHESTEQYHLRKVRILYFLEDDSISVIEPPVENSGIPQRTFIKRQRLPKEVSGDNLPQSYYSIRDFNIGINVTFYTRTFRIIGCDKFTENYMTQTEGIVLNEKEKMPNDPYIDIRNRPRRDYSVPSVSPVVHHNDKLKKFLDFDRQVLRFYCVWDDRNSMFGELREFVLHYYLVDDCVEVREIAQPNNGRDPFPILLKRQQLSKNENGNEKYISKDLRIGAVVNVLGRPFLIRDCDDYTRRYYSDNFNLTELEMAPIQFEGEDNVVHGLAQETAPYNGYGTIEDSLGSCKYLVLKPPKKDFIKMLENEHKVLRFVAKMESKHKEDKDRRFVISYRLADDMMTIYEPPQRNAGVLGGKFMERTRVLKPVSHSTLSSVSALGSTQTPLYYNADDLYIGARLDIFRHKFVLLDADEYVFNYMEERPEEFKFSDRNLVVKNLKNLGKVNGKGQEVLKKLENQDKTKSGLLDRSAFVKTVKEVFENQLNEHADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIKEAFKVFDKDGNGFISAAELRHVMTNLGEKLTEEEVDEMIREADVDGDGQINYEEFVKMMVIFLSFKFFLFLNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7T4</accession>
    <name>A0AAD5U7T4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small COPII coat GTPase SAR1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Small COPII coat GTPase sar1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="primary">SAR1</name>
        <name evidence="24" type="ORF">HK099_005500</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the small GTPase superfamily. SAR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7T4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00879">
        <property type="entry name" value="Sar1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Small COPII coat GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
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        <property type="entry name" value="Small_GTPase_SAR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45684">
        <property type="entry name" value="RE74312P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="14 19" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="21" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRM" evidence="23">
        <location>
            <begin position="80"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="192"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="326"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="405"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="451"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <begin position="517"/>
            <end position="524"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="519"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="520"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="524"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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            <position position="524"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
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        <location>
            <position position="563"/>
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        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <location>
            <begin position="607"/>
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        </location>
        <ligand>
            <name>GTP</name>
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        </ligand>
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            <position position="607"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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        <location>
            <position position="608"/>
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        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
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    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="610"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="644"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="645"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606687-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606687-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAJ3226147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="667" mass="74334" checksum="AE6802124E70A4A6" modified="2024-05-29" version="1">MDDDFYFDNKKYAAVDELFPKATSNMNFKPNQQQPMLNKGQKQPPFKTNNFATQQNLNNNINSVSQPSTSTNLSNQPKAKGLILSDLTWWTSDSDLINLCNKIGTGESLLENEINFQEFKQSGKSKGIVYIGFKDEESCQKTKEYIENSEINGVSVQVQFSFTPTPFKVVPKDPKELRQQSNMEFQKQQNLGNAVGRRGSTPQQHTPQMPINPQQQFHSNMHSNQWMGPNLPNAQFRPPSGGFFNPSFPQGPPNILGPAMNPMMGGGGMMGMGGAMGTMAGMNPMMAQMNPMMGMGGPDMMNPMMGMGGPEMMGMPNPGMGMGMPGAFTPTPRGRGAFVRQGHGGPQMQQNFQQQSFPNQQSLPNQPLQSDGNANGEVPKMMGGSDHGSESKRKRRSRSPPPTIKTERSESNKDDNGGRRSYSEYEKVPSPEQREFNRGESPTTPVVESPSRNKFDDSEDSRNKRESDRDSKKRRERSSDRSSRRNRSRNMFLVNWFWDVLSSLGLVNKNAKILFLGLDNAGKTTLLHVLKNDRIAVLQPTLHPTSEELAIGNVKFTTHDLGGHRQDGIVYLVDCADYTRFHESKAELDNLLAIEDLSKVPFVVLGNKIDAPNAVSEEDLRGALGTGKNINKDIRPIELFMCSVVMRQGYGDGEIIFICQFYLIHYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7W1</accession>
    <name>A0AAD5U7W1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7W1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="22711" checksum="209B46263DE4A20C" modified="2024-05-29" version="1">MEANYLRQSVGPVLADAFASLYAHGIDSHNDPTHPHKDPIGFVGRYLLEHDRVQKESALAILKKQPLLELQKLLAEKKVEYSFIRNQTYNELKRTLEERETRKEEEKKRLEDELQEKLRLETEETIRNLTAPKDDTEEKETIEVKDIKENKDIEEEDEEEEGLNEKEELVEDSLAENPSIEDQPVEIQDNETGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U803</accession>
    <name>A0AAD5U803_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">QCR2_2</name>
        <name evidence="13" type="ORF">HK099_006711</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U803"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000039">
        <property type="entry name" value="Ubiquinol-cytochrome c reductase core subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF209">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="11">
        <location>
            <begin position="14"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="12">
        <location>
            <begin position="163"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3228086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="419" mass="45615" checksum="8B4207E66591946A" modified="2024-05-29" version="1">MVSYSKTALFIILVSTHDDLGPISTLAFVINAGSRNEELEYPGVAHFVKNTLNIKGDNIVRTIREAELRGNSFYTSHSRESITVATDFLRDDLVDAVPLLVNNIFNRSLEPYEFLDARRLVAEESKAALNEPSVFLADSLHRVAFRTGLGNSLFASTETLNDLKRSHINNFTSKFFTPNRIAVIGSGVNQKDLISLLETAFKNSMLGSNSNFLQQRSKYYGGEERYSSGHSEAHYALAFPSTSFNSNEYPTALVLRALLDGSRRSPWGIVNGSSSLLANAASSSCSVVAFNTSYSDAGLLGFYIKGNEGDVKNVVQNSLNALKSVASGVGFSDASITRAVKTAIVDLECSATRESRVRDIAENILSSGSNLKTGVLSDALSKVTAEKLASFAKTMINNKPSVVAYGKYPFLPYLEDFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U890</accession>
    <name>A0AAD5U890_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005251</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="6">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="7">Glycosylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the paraoxonase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U890"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004064">
        <property type="term" value="F:arylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002640">
        <property type="entry name" value="Arylesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051288">
        <property type="entry name" value="Serum_paraoxonase/arylesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799">
        <property type="entry name" value="PARAOXONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11799:SF12">
        <property type="entry name" value="PARAOXONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01731">
        <property type="entry name" value="Arylesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="7">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602640-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602640-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602640-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3228241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="601" mass="67195" checksum="67250EEF3A36F8C3" modified="2024-05-29" version="1">MFAIFVSSAVKLAPLSRIVGNLAHAQSVDDIRTEDIAIDRESKYLFVSNLNLSEFLQNRKESHGAILSYNLKSKQLKKLPIKNLRSGQFNPHGISFFHDHNNDVKYLFVINHKLEGDSVISFKIQYGLDDEVSLTFLEEFQNADMISLNDLHAFGKNSFVATNDHNVRNPVLGFLTDLFGIPYSSVILVKNGKNEGKVLNFVSYANSAHYDAKKDILYVAHTVSKLFSLYRFNGSRKAELIQSVNLNTMPDNVEVDESGDIWLGSHPKIFKFLQHLGNAEKLSPSQCIKVSLLDSGLVDKFETVYYNNGSEISAKEFTTKETTYFDPLWSHAGIVIDSNFLPGKGLTPGKLYLYESIFSGTVLGYQYSKVLPVDQPKALIKGRYAGPQVRDFQAVMDESGADVGIFPLSRETRDFVNRKAEAVKNSFIKFHVAAANDSMFDKIKQIKEKYNLGYNSDDESDEEEVKENVPIDIVVREDSSVDATVTRNRLAFKAKGLLSSVSSSFSSLNITSKSDGNLNSDKTISKKKTKGAVFCSELVAMIYKQVLLKEEDFKDPGRFTPIEVAAAKVFSPSFYVKKDGTSFLQNSVLTNVMMVDKKVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8F5</accession>
    <name>A0AAD5U8F5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Potassium voltage-gated channel sub H member 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KCNH7</name>
        <name evidence="3" type="ORF">HK099_005244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8F5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098855">
        <property type="term" value="C:HCN channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003254">
        <property type="term" value="P:regulation of membrane depolarization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051413">
        <property type="entry name" value="K/Na_HCN_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689:SF5">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="578"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="769" mass="87063" checksum="D13C2800BA66DB8C" modified="2024-05-29" version="1">MLSSIDLLSTQIGKNCHLNICEDEFFSNNLDFLKRKVDGNFQSKEAIHSAKKGFPFDSGRNLTNMIASRNSLRQDFPVLMDFAVEQAIHLASLNEIDNNHQKNSGYSIAPSEQGFEQIHQTAEAGSEAHGNKNYIFDVLRANLDSNQKEIDLEAAKEINEDFMKVDAKRQLQSKHHNSGDSLSSISSGDRKPKAFQKKSAEQQLHRNFLEKKKSEKVVDQWEGSIELDRKRVMTSLASDSNTPAENGWSMNGFNNCGSSLESISASDLEDQSLVLGCLKHSHVQLNKKSSQCKVEGPLDVENIPSSNANNSPEKNNDKVPKPEGENSPVPATLNTTANNNNTKVVEGATYLDQYCFTAAYNEFGTRLSGTDRAFEIKKNCESEINKLRAVHPLSYFQTFWDFFMSSKMQSFQTQSWKLLEKEGILAKSVGAQYTWSVFAAISNTFPVTGYRPTDSYEQWVTIVLVLIGATLYATLVGTISSFSFGLDSSGRLYKEKMDEVNEYLNYKKLSPNIKNRVKQYYELKFKGKYFNEVEILGELNNSLRQDIAIHNCRDLIRKVPFLCRSQNDGRDEAFNRCIASALQPCYYINGDRILEAGDVGNEMYFIFAGIVEILVGGKVVAKLNEGSFFGEVALLGQVPRTATIQAHTNCILFSLHRLDMEEILKDYEDMSIQMQEVYKERMEKVKKENEQKAKLLEEELERKKTLQKNVEQTEENCQGDNNEKKTLAVEEFKRKQSENNETLKRKNSEAVAEGARLNTDLTKRKSIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8N6</accession>
    <name>A0AAD5U8N6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lysophospholipase D gdpd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GDPD1</name>
        <name evidence="10" type="ORF">HK099_002173</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycerophosphoryl diester phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000017">
        <property type="protein sequence ID" value="KAJ3227422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8N6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052271">
        <property type="entry name" value="GDPD-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42758">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42758:SF2">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="9">
        <location>
            <begin position="8"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="287" mass="33001" checksum="44AB1BA1444EFA29" modified="2024-05-29" version="1">MNNFLSNVQLMSHRGGSHEHVENTIAAFRYSANVLDVDILELDCHLTKDKQVVVFHDKNLQRVCGIKNKKISDYNFDELPKLLLSENLIPNNAVDKNNLDHVSIPKLQCLFDEFKDKKMHIDIKSGPEELVLKVGNMIKEYRREHLTIWGSGVSYWNDMCYKHFGNTIPLCFSLRGVLWAYFLWVIGFFWAYAGNRYQFMCIPNKPMLMKPEWFKALNKLGIPVVIWGLPNGGVNTIEGFEEVLLSGANGICTDRPTLLKEWLKNNKLADVVENDAAREKVEVVVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U929</accession>
    <name>A0AAD5U929_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor G, mitochondrial</fullName>
            <shortName evidence="7">EF-Gmt</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Elongation factor G 1, mitochondrial</fullName>
            <shortName evidence="7">mEF-G 1</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Elongation factor G1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">MEF1</name>
        <name evidence="9" type="ORF">HK099_008313</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U929"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04091">
        <property type="entry name" value="mtEFG1_II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000003">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000029">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000022">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047872">
        <property type="entry name" value="EFG_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009381">
        <property type="entry name" value="PRK12740.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636:SF2">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="35"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="111"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="165"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="741" mass="83377" checksum="6EE76EE1E9C4D2CB" modified="2024-05-29" version="1">MNHYNKLKLRDYSAPNVAEAKENLLLKPTELNRLTNLRNIGISAHIDSGKTTLTERILYYTGRIDDIHEVRGKDNVGAKMDSMELEKEKGITIQSAATFTRWQDKAINIIDTPGHVDFTIEVERALRVLDGAILVLCSVGGVQSQTITVDRQMKRYSVPRLCFINKMDRAGSNPWRIIDQVRKKLKLNCAAVQIPIGAEIDFKGVVDLVEMQAYYNSGPKGEIVEKQPLPSELLEFAREKRTELITTLAEVDDFIADLFLEDIEPTNQQLKDAIRRQTLSRNFVPAFMGSAYHNKAVQSLLDGVIDYLPAPHEVENLALDIDKNEEKVKLSPSSESEFVGLAFKLEEGRYGQLTYIRVYQGTLKRGNWLHNIRTGKRVKVPRLVRMHSNEMEDVESVGSGEICALFGVDCASGDTFTDGSLNYTMTTMFVPSPVISLSIQPKGRESANFSKALSRFQREDPTFKVHVDSESKQTIISGMGELHLEIYLERMKREYNVETITGKPEVAFRETVRNRTAYNYTHKKQSGGSGQYAKIVGYIESVEKEELEEEETSATDSTQNNIFENSTVGMNVPSNYVPAIEKGFYESCEKGFLSGHPVTNVRFVLEDGLSHQVDSSELAFKLAAQYAFREAFSKAAPVILEPIMSVSVSAPSEYQGTAVALLNKRKGVIVDSEVVDDYVEVQAEVPLNEMFGFSTDLRSITQGKGEFSMVYLKHLPCNPQDQMKLVQEYQKKREKETKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9C2</accession>
    <name>A0AAD5U9C2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000035">
        <property type="protein sequence ID" value="KAJ3226485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9C2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041991327" evidence="2">
        <location>
            <begin position="22"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="162" mass="18251" checksum="5F9DA04520EEE0E1" modified="2024-05-29" version="1">MNFQQPSQILVLIFWIVILIATELKVERHLTETNPLKQPLLFSSNNNSSISSDYNTLYSNNNSQAILFPKLSSDIGDYMDANGIETIEPFFDENGSWKGIRRISVAFSNENNSDTRSSLGSKKKEADVESQIEKNNNSTRNCYPWLFNQSTSTTLSDPSTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9H1</accession>
    <name>A0AAD5U9H1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rho GTPase-activating protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ARHGAP9</name>
        <name evidence="4" type="ORF">HK099_005260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000040">
        <property type="protein sequence ID" value="KAJ3226263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039102">
        <property type="entry name" value="FAM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059029">
        <property type="entry name" value="FAM13A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15904">
        <property type="entry name" value="FAM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15904:SF17">
        <property type="entry name" value="RHO-GAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26116">
        <property type="entry name" value="FAM13A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="21"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="631"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="908"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1225"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="631"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="679"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="908"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="934"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="948"/>
            <end position="966"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1292" mass="144458" checksum="BEC0174358C190B4" modified="2024-05-29" version="1">MLKLIRKFSKSESSDNIENSPQFQKNASTGPTLNSKSIFAQPIKILLERHQNKNSELNYQHGNTKNIPLSLKLFVREIEKEETGEVDFSHIERADIPVIWNLMKSFLREIPEGIVPKIYFHSLIDAGESIENLKKAIKGIEQPYLDNLIFVLLFLIRVSKKSESNKMNINNLAIVFSQNIFRLPSEDFTSVGGSSDRYLVESTQITRLLQIFLENFWDLFQEFISGSEQLKNFYQVADELKTTSDTKKHSMLTGTSVHSRASTMESSFWTSVISTPELLSQPSPTPSQNVLINSMVHTAVSKVLFDDPEGVSENGNLDISRLSSGSEDEESEITSKFNENICDSEKSTTLPNRIMVSPTKSNFSDFSSDISLSPTSTAPTVGNIRGTHQSVLDELKSALKRRRSPSLESTVKEKEEFEGNHNTKIKTTEESPESECVIEKNINSVHRVDDQLNVKLSRVENEKAEVKLTENNLVDSKDSENDKILGSLSNNDNVHHPQLVSLTKNRPKRPGNQNSKVKVLKINTNTKENPIQSYNTIENFKLIQKTALSPTTLNASTLHFDPSSPIDKPTQFESDTHYTQNLNSPSVATDKQLSSIENLNAANFNSTNSSKLASSPKTGATLQNNMNTVNNVSTLQSSPTSSVLPSKTKIPKLKKRLSGTSTSSGNDEEPIITLKESAGSHSIYQSSRIPTSQQKKNTSFSNHEAYQGGNVFEKETAIVNESFIKVYNIADKADTFPRAKNHKLNLQTSFQQTNEKLVNIETRVKKTYGKAAQNSNDLLTPVTPITPFKKIPNSSNSLVDEQPASSATEIIMKKKSHNMKNNSDAVTPGKNDKQMLKQGDMMQNDNLIAGNENEEEEILKDGAESLIKFSSAKSPTSKKAVVLTTTTNIPNSELYILKTSSPGLNTPIASSISNKNQASRRKVSLASSDSTVDEGVKDKIARSFDKTSPTSNSSSKKNYNSPVSPKMGEKIKVQHVSETSKTSKNVGTNINSLKLSIPEVSLNNVSEGDLDEIKQKCKILYEKIKSARSKVEIEGEIVYDDRQQSANVAASSLPPPSPADISPLTPALLVKKVSIKSKIEKDTKKEADENSIQNINSSSLTPCQLSLRKLKRLKILDDREKFRNVEDLSFKDLFEESDRLKKELTKLKEIYTAESPITGEKPKIHAPKAEKEILRLLHQRFNSINQLKQHKQHDEAASATNTNFTEDFSENSVVSENVMATLEEKELIKKKLKNMKVEKKKVQRSLTTFQDNFIKKNGRPVQTLEDREPIKEEYRLYKDIKMEISELERQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAN1</accession>
    <name>A0AAD5UAN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004418</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAN1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3226674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="28413" checksum="D992650896F8FD7B" modified="2024-05-29" version="1">MKTYPKEIKNATPSFLQSVFAEGLVTFLFLFTVMAFSINNVRQGTPENLVLAAIGVTLSSTAFIYSFGDVSGANFNPAVTVGLVLNGKMPLLKGIAYVTVQLIAAVMATLHVQAVFPNNPLGDHTSIFDALLVQPNAQSDLLTFFLMEASLTFILLYVIFSTAVDKVENVDAILVNDGDKSFTVYTTIPASKNTFAPIAIGFTLGFLCLLGGSTSGGCFNPARAFGPALLSGNFDNFWVYAAADVTGAVLAGITQSSFALGSKVSAAKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBP4</accession>
    <name>A0AAD5UBP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-serine ammonia-lyase</fullName>
            <ecNumber evidence="3">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007823</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBP4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF2">
        <property type="entry name" value="CATABOLIC L-SERINE_THREONINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="7">
        <location>
            <begin position="4"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="297" mass="32166" checksum="DB34706C1174CF6E" modified="2024-05-29" version="1">MHLKTPVIELPSNGLNLNKVFLKLDNLQPSGSFKIRGISNLVKKAIEKLPKNQPVKFLVSSSGGNAGISTAYVGLKLAIPVKVFVPVTTKEFVIKILQANKADVLVGGESWVEANEQALGFFKAAQQEFGIDLWEGHSTLITEIEEKIDFVIVSVGGGGLLSGVLEGLRAKNSTAKVIAVETKATSLGAKTVTENLIHSCKSYGTENIFSVVVEDRLAVQAISKFADDFKFLVEPACSASLSLVLLKEGEEILKEKVFKKINFTEKKLSESNILVVVCGGNSVTLKMITEWKTLFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC10</accession>
    <name>A0AAD5UC10_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006021</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC10"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041989539" description="SH3 domain-containing protein" evidence="5">
        <location>
            <begin position="17"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="756"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="512"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3228141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="863" mass="95875" checksum="2B516797B072905E" modified="2024-05-29" version="1">MKLLLLFIVFISYSTAQSPPIGASTVRISNGNLIFGGKTIDTVTNTLYFVSDAPNSNFTVLENKADNPVFVPNPAYRHCCVSDYNEETKLSGNMYCYGGVNSPNLIYKFDTLSMKWVNPISVAENFRSRAGHQCFLSKQGVMYVYGGIQLVPLGAISSSSLINAFNTESIESNPTNVTAGFVDTPLDYISNRQNPVLMTSPATNQQGLLLFGEDPNSSEIPSVLPSLAFVPLSETGFFKPLKTSVFQPQFTTGTTCTSVFYNDIIDVYCFGGKILNSTLPTNQFWTLNSTLYWNDLSFKKINQPTPRDNALMLQSENLLLIWGGGNAGFASANTDLFSKDQPTNDQNIYRFDLASQSWLTPVPFLHETKTPITLPPTMTPSVISNVQENGLSALNIALIVFAMVFLIIMVVISVVACYYKKKEKINFKKSSLDVENTLASQVSNNLLASSTQNRHSDKNHSHDFSSTHLTPKQSDFTFIPNSTLLENEERGTVPLTLSEVIEVDKEIENMNGINKNFSNSNKSSSDQPSSTTPPHYSPPSHPETGHFSVSSLSDRDTVKKNNSKSSSQLSPLILQPFPTNKVYNSENISNGSAESFQSIPNSVNNTFGVQPGAIKEMKSIDSFKSFPSNAKYVEKKRYSSHTVDTATTKTSEGGYNTAKESLEDFDGDYDNLSSSSSFINELFHSVNIPLRETSKKNEDILSEIKDPKALSGSKLATLPLNEISKAKENLTKYPNGKGKYLSVKPDDYSQVQHKDLKGKTFVTLRSFEPRAGYDDEIFLKVGDLILIYEVYDDNWCRGENISDANKVGAFPFNYVERVNWGAVEEEKEINKFVNWKELEESNSMLRNKKSFSIDVRRSSLIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC57</accession>
    <name>A0AAD5UC57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FERM domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FRMD8</name>
        <name evidence="2" type="ORF">HK099_002909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC57"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051594">
        <property type="entry name" value="KRIT1/FRMD8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057096">
        <property type="entry name" value="KRIT1_FRMD8_FERM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13283:SF10">
        <property type="entry name" value="FERM DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13283">
        <property type="entry name" value="KREV INTERACTION TRAPPED 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00373">
        <property type="entry name" value="FERM_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24522">
        <property type="entry name" value="KRIT1_FRMD8_FERM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FERM" evidence="1">
        <location>
            <begin position="28"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="419" mass="48782" checksum="94AC18DA69F9A0E3" modified="2024-05-29" version="1">MDKVNSTTVDNWLSPLQKHIRNGKVEFITIKVRIFGDDMESDFCAKFDEGPLTAEKVCNAVAERQGLSENGKKVFALWIIGRDIELQLRPKHNLFQLMENWNKWVEKYTHFPEANNPAHPICKHWFVFRKEALDSTPVSEYEENALTLLYGEAYQNIQSSRYPCTVEDIVNLSALQLQTHGDYNSIRHTSGYLVEQDRWLYLVPLKMRKKLSAKTWGKRILEAYARHVGKSQTAARKRYLEYVRKFPFNGNSFFPCCQYLPPGAYFEMRQQHHLFGVGADGISILDQDKNKLLFHCGWKNLVWQFNDDNIVMWVLKEGTTINVDEKKKQKYSKQFEIITPQAAIIQNVIERAIHLTKKEETPLNLTYSTRDLKSLNNTTSSLANNRFKEARLTRMEKARSYITDIQKVNGITIIDEDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRD4</accession>
    <name>A0AAD5XRD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002088">
        <property type="protein sequence ID" value="KAJ3199550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRD4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="331" mass="37982" checksum="855C453A207965D9" modified="2024-05-29" version="1">MNRNYSRNTNDQSDNKDDSDQNSQNREFFQEKFIRGRPDLLDKIQRKSKGKYDTSGTGIASSSNNANIVSPQLLQVESSTTTNIRNSPTPTLDNEIEDSSEQFSPMEENLKLSQQDNINKIPDFNEHIPHQVSYKFPPETTPKLEKTKGSNVTENVNKKLHLENQELKKMLMHMNKSINHCMQLLQTLNEKSSKHEMLLDKILMNWNNNSVSVNTSFLASDHNNYPLQQQQHREKQHRLFRNSGNNNTSNCVPQNPQLPPLGMEDQINKLASDRILPPVQHIIRKQGSPRHLPYDPLRFANRPISNTVSNFSDTISQQNQSLAYPHVSSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRS7</accession>
    <name>A0AAD5XRS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002067">
        <property type="protein sequence ID" value="KAJ3199652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRS7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="81" mass="9088" checksum="4A0AB0DF5C499917" modified="2024-05-29" version="1" fragment="single">MAPQVESYNNLMFTPVNNILFNKTCSKFYPNDTSAKTSTKSFKKPLPSISQFPQSSSTYIPCSTIPPQVIRTNKSSLNHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSL0</accession>
    <name>A0AAD5XSL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000949</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001241">
        <property type="protein sequence ID" value="KAJ3205034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSL0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3205034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="109" mass="12413" checksum="60956272ED7EDEF9" modified="2024-05-29" version="1">MMKFGDPTTTCILIGDWSVNSQKCHAPTKGKGFRTMFRRAGYAVHLVNEHKTSETCQLNLNGKVVNRLWNRDDLATMNIKSVVMETLQNNEPPTRFRKITPEPVFAGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT62</accession>
    <name>A0AAD5XT62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000918">
        <property type="protein sequence ID" value="KAJ3209896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT62"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3209896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="124" mass="14560" checksum="D95397093C10F342" modified="2024-05-29" version="1">MEKKKIEENFELEKVEIKKKILESLLEKKRRLREDNDFLDINLDQADFNQNQNYFDVKTLSTRKSNTRNKLIQEGLANGSGREKKRKGVEKGPCLPIPLKESDQQDDIAKIRKECSNGRKIRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV08</accession>
    <name>A0AAD5XV08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001415">
        <property type="protein sequence ID" value="KAJ3203543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV08"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="72" mass="8600" checksum="42C6C7453513E5A0" modified="2024-05-29" version="1">MLKNDDDIVKENDGLRKEKEIQVKERDDKLMKEKLTEKDKLVKEKNGLLTKKVKLEKEKESEVKEKDDLKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVJ5</accession>
    <name>A0AAD5XVJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001805">
        <property type="protein sequence ID" value="KAJ3200958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVJ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="29788" checksum="DC70334EC97BA3FD" modified="2024-05-29" version="1" fragment="single">SLPKENDFTFNLLLPFIKIFSKIEDKVFLKIIKEEIFEKLTSDEYNCFNLKFNINLNLEKISKTIFKIGSQSFVLHNNRKEMYSISNSISQFLGTELQLLDENENLVNDAKDSTTLDEKKEEEADNKATPFAKPKESDEDSWEEVEESGDEEVEESGDVDIKDSSEEPIESPKNICETDINNDKKTILKVETEISSSNMKRKIPKKNKESEKFESKSKKFKVHVESDVTTELNGNEVVKVEKKKKVSINLNNNTTKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW83</accession>
    <name>A0AAD5XW83_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Programmed cell death protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDCD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000236">
        <property type="protein sequence ID" value="KAJ3221324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW83"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="entry name" value="PDCD5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840:SF0">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015730">
        <property type="entry name" value="TFAR19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="Double-stranded DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="15522" checksum="8D874F5BF5E5D532" modified="2024-05-29" version="1">MDGDEELNLIRAKRMAELKASQGGHGPSFNGQNQQSQEQKQQQLEAQEEQRKNLLYQILTSDARERLSRISMVKPEKGRQVEQLLITLAQRGQLREKVDEKALIELLSQVKDNSKATSIKFNRRKSASDDDDDWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWN0</accession>
    <name>A0AAD5XWN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SWI/SNF and RSC complexes subunit Ssr4 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000194">
        <property type="protein sequence ID" value="KAJ3222059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWN0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013859">
        <property type="entry name" value="Ssr4_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08549">
        <property type="entry name" value="SWI-SNF_Ssr4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWI/SNF and RSC complexes subunit Ssr4 N-terminal" evidence="1">
        <location>
            <begin position="7"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="101" mass="11462" checksum="A42BEB2A38848039" modified="2024-05-29" version="1">MRNTFGEIPPEAIYNFLLRAAQHVLESGFEWVNLNCPPEGSIIIIKIPAEVSTINSDGYGWMDDENRTVVKVDGHDIEIFERVSGFKPIEKFASVYSFIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWS7</accession>
    <name>A0AAD5XWS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWS7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="591" mass="69038" checksum="1C1C31D622F508C0" modified="2024-05-29" version="1">MNALAESESTLHYKKCFFLKKEGFISIDIRHQVFSWNTCYNYEKLVEVSIQNIIGCEYDLELCELKLLCDENYGKNKKIHVFKLSSNNELKDLIIKLNELHTGFNCMESFKGNLEKPRHNLKNKIALLRKNNKVNVFLPESTKIQATPDVSKRYFNTSCLKGTQNVFLQKGKDIFDGNNINCIDKGLDVERSLDDKNSMTNFETSPKTTLTDGLPDIMKNVLKLDNTPPNRAASTDYLNISFQKREALFYSELKENEQNTINISVNSESYFEEMVNKLMNLNSELIFETCWVIKDENSNQTFDAVDVRRNKTKHYLSLFIMAFISREFIAEKDGIGLLPKSINDDTLYTRFRSFYVALLKTISLDIFLPSNISDSFYKVFLGITLCLSDFENSIPVIFKQYLEQFENSTNPLVKLTSALTKDLIFSRTGMKSVFYMSSTSGEYSNFLKKINSLYTFEEFKANFTSRIEVFHCDILDNLTLPCTEIERKDLLHTESSYKTFRTFVHNLSVPDLQDFWFKATNELTYNKNVRFLFKCNQESNIFNVHCQIQEQIICWNLNYPENIKVYFISCPYFENRQKLISSINLWRRSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX11</accession>
    <name>A0AAD5XX11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001892</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000159">
        <property type="protein sequence ID" value="KAJ3222787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX11"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF4">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="218"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="GRF-type" evidence="7">
        <location>
            <begin position="339"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3222787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="407" mass="46627" checksum="8A42C8255E018EA6" modified="2024-05-29" version="1">MSFDYNFAYLLQMFSDIKKEAEIIDALNSSNNNLEEAINSLLVKKRRKSNTIDGYFIKKTTVSDSSVQPCQLSVPCTIKFDESTTQKNAFSVLKWSDATTSSTKPKILNAENVSEFIPGKLLLNFLPSELADELLLSMISKAKDWKVSKFIINKRQVESMHTTCLFAEDPAILRNHYYYGVNILKLTKELAAVKGLVDNCVNETLSQRKRLKLESQERWISSLALGNYYEDETKGVGLHSDKLEYIGPHPTIASLTLGAERLFKIKKIPFPGSPPETFHVMLPHNSLFVMLPGFQEGYKHEIPKQKVFEIKPNKLSGMQRVNFTFRMIRKEYFDALPYCFCGRRAVLKVVFKKKDNFGKHFYFCGGVKVDDENTEVDKSDSVEKTESSKKIILAKNCTYFKWLEDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX43</accession>
    <name>A0AAD5XX43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Glycoside hydrolase 2 (Mannanase, beta-galactosidase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">BMS1</name>
        <name evidence="13" type="ORF">HK099_006186</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. BMS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000519">
        <property type="protein sequence ID" value="KAJ3215795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX43"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01882">
        <property type="entry name" value="BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000105">
        <property type="entry name" value="BMS1 ribosome biogenesis factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037875">
        <property type="entry name" value="Bms1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="12">
        <location>
            <begin position="74"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="436"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="440"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3215795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1188" mass="136542" checksum="1C878F1AF5D035F2" modified="2024-05-29" version="1">MDQNVDRKQHTAPKSGRKADKKKEKKQPKNQQKNNPKAFAFNSGARAERSARRNLDNSEHKLHVPLIDRSTLEPPPIVIAVVGPPKCGKTTLIRSLVKKFTKHNLNEIKGPITVVSGMNYMYIHLFIRIGKHRRLTFFEANNDLNSMIDLAKVTDLVLLMIDASFGFEMETFEFLNILQTHGFPKILGILTHLDHFKDNKRLKTTKKKLKHRFWTEIYQGAKLFYLSGLINNKYPKNEIVNLCRFISVMKFRPIVWRNTHPYLLIDRVEDITDPADIADNPKCDRTVTLYGYTRGTNLKEGSKVHIAGVGDSIVADISILPDPCPMAQKVRRSLNEKQKLIYAPMSDVAGILYDKDAVYVNVRSNFNKPQGGDDEIFEKSSGEKMVMNLQDTKQTLVDQIGNSEVKIFSSSTPMKANDLPYVVENVVENDRTRRRILFGNEEEEEENELPLSNDSEDDEDNSSTDVNSEEESSEDEEDFEEESDDGNLEAGERRRVDKDFKYANIEENENKKKSLKAKKNIDIAFADSDDDLSGDEEIIEHRGREVLEKFNQGSDLFDGKILEDDYDENVPNDLEIDSFNWKENLASKASINYHKAKAEQRKKNLMYLIYGDSNNPEPSLDEDLDSVEEEMSDLDDTNMFKLKKKKNFQNITLSAIDTSKVEILNDDLAEEWGSEEFLDSIRHMFITGDSEMNEENKEEEVFGDFEDLESGEKVEAESTEISEEADLARKKEVLKKKFDAQYDSDSDMSDSPLNSSNIFEKTKAEFAHQKVINDKEFEGVDETTKLKLEGYKPGQYVRIVIHQMPKEFIEKFDPCYPVIVGGILSSEDNFGFIQVRLKRHRWYKKILKSNDPFVVSLGWRRFQTLPMYSLDDGSRNRILKYTPEHMHCLATFYGPISSPNTGFCAFQTLSDNTSNFRIAATGVVLDINKSVEIVKKLKLIGTPIKIYKHTAFIKDMFTSSLEVAKFEGASIRTVSGIRGQVKKYLTKPEGAFRATFEDKILMSDIVFLRAWYPVKPKKLYNPVSSLLIGGNTEWKGMRSTGQVRYENGLAVPNLVDSTYKEIERKPRVFNKLKVPKSLQSQLPFKTKPKLLKKQQKKTYLQKRAVVMEADEKKVYSLIQQINTIKNEKDLKRKVKDKEKKEVYLKKKALSEEKSLRKKKDRVKEFYEKMGKSGSAFEDGPPKKKFKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX73</accession>
    <name>A0AAD5XX73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000132">
        <property type="protein sequence ID" value="KAJ3223395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX73"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="105"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="390" mass="44109" checksum="3DBA777442FA74EF" modified="2024-05-29" version="1">MSTKTINTIDALLADLNDAIFELKEGEQLNTTYQSNVLTKENNPNLKILIPIVPPVRGASNIPPPSYDTISNNLSSSNILQNNEENIVYFEAPKDTKLSSISSLPDAFGGWLQKVSYKAIIKTRQLKKKYLILANCTLYIFNDDHKDEEFDDALPINKKSVCRVSEKGIFVLEFMTEYRETIADDGLGGVLEMNGLGSVKQKKQLEFQCSDRDEMMVWLDCFKEVIQEAKNGRVPLGFEKNQKPKQQMQQLAISSPAYKDSSSVEYDYRSTPSPSPLNLVSSYRDSDSTFSNTNLNRSTINSTNSNNSQERHLPPVPAFIDEYLNPASPIPSRSSTVKSNTSSHKSGENMFAQTHQLSLKEEKEKQKRLKKEKKEQKAQEQMKFFASEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXD4</accession>
    <name>A0AAD5XXD4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXD4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF6">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13899">
        <property type="entry name" value="Thioredoxin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="1">
        <location>
            <begin position="368"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="420" mass="47930" checksum="EC8F554839A8FB99" modified="2024-05-29" version="1">MSTADDDSVLYSDQIIQFLDITGSTPEQALNYLRVNEGDVEQAISMYFANGGTDLINTDTYTPVPIIEDSTNLASSPQLNTLNDFYDEDGVRAPIAPQQSTMINPEHYGNQSHWVDEPELTGEYFSNDSISSSRLTRPFSGRDNFRLQRGGVNPFSEDDNVDETTDKIVDKRTQLENMFRILVTIQDTDNFSCHTMLRDVWNNADVQKLIKEKFIFCYYLSTHREGIRHKITYPYTDYPYTAIIDPVTGERVAKWIEALEAKSFMELGTKNDSINSKKIFFIVNEFLNQKMEAQSVQPDKKKQKSVLELSEEEQLRLAIEASIGAKAGESSSSHEADADRKTKIMYCFILNLLIAFNRIIGNIKPEPTAGDITRIQFRYPDGSRDVRKFLKSDKVLNLFEYVKGNEKKIGDQKFDVKLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXN5</accession>
    <name>A0AAD5XXN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PPP2R3C</name>
        <name evidence="4" type="ORF">HK099_000268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001055">
        <property type="protein sequence ID" value="KAJ3207422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXN5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030865">
        <property type="term" value="P:cortical cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035303">
        <property type="term" value="P:regulation of dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039865">
        <property type="entry name" value="PPP2R3C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12085">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12085:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3207422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="303" mass="35513" checksum="5CF53518C003572E" modified="2024-05-29" version="1">MEIKKLISLKSKNIFQQTLHRAAYKLKLDKQEGKLITNDELDTLWDLLNETAGFTYKSDQENVADDKLINFKEFELVKERLNNPKKFNSYFKPSIFVRFPGDESCRISILQFYNYVLRKVSLDQAWVDLAKYDLDCDGCLNEDDLNKYIGDLMAFMNLPNITISFKKFYQCTAVRKFMFFLDSMKLGKIPIINIILSPILTELFELRESEPLEGFEKRNWFSAYSSQRVYGQFLNLDTDQNGMLSREEIAEYNNGTITGIFFDRLFEECQTYKNEITSILEMAVIKKMVTMGYEEMNADDITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYB6</accession>
    <name>A0AAD5XYB6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_007699</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM TET family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000770">
        <property type="protein sequence ID" value="KAJ3212637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYB6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12254">
        <property type="entry name" value="RRM_hnRNPH_ESRPs_RBM12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034870">
        <property type="entry name" value="TET_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23238">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="335"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="12">
        <location>
            <begin position="473"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="12">
        <location>
            <begin position="528"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="420"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="613"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3212637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="690" mass="78396" checksum="3F2411B69C6B6A4E" modified="2024-05-29" version="1">MTGEEISIVDEKNEESENAEVQIPKVNNKLQDIFDSANEKENCLLLLPQTEETNTPLETEEPEQMETPLINLFDVDPTEEVESSEEEAKETVEIVKVKTPFDPKKPFLNDFLIALDTQVTENRNREVIELSFAVVSVREKLIVHNERFFCKPEKTKLELIPSRSRSQKAWFEDLENAGSLQDAVNNLVAFIEKHFISKQKSFCFVSLGEIDFRLNLAADAKSKKISLAPYFSVFFDIVQETNKWLSMNQLTGSRVIGKDTLPGICSDLNIFTNRGHHASLDCTLTIADICIKLLARVEDFVSTRYDELAEYAEVPFNIPIDITAEAEHFNSSHSKCIMLQGLSLKSTKSDVEKFLNNVNIEKIFMVNFSEGNPNGSAFVIFKEHEDAKNSLSSNGRMFDKCIIQVIPSDENKMKDMKHLLGSFPAGNQSNFKRDYDDDNYSRQSSSKRSRGGDSRHSSPRNNSPPPKKHQEPKVGDWICPNISCEFPNFPTRIECMRCQTPKPYSAIINEGPKRSVNNRVLQKRDTDRPGDWNCPNDICKYHNYSTRTNCYRCQTKKPERVEPPPNPIPPPAPIAYVANPQPFPIFNYGARQEYSTYYTQYSQPAYTSTYPPYSAAPNPPPPIPISNGPYSNPPRGMPPQNGLGIQPYPPMQHNHGPPQHRRVPLTANQSSYSQNVPTYIRPPIQYPRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYF9</accession>
    <name>A0AAD5XYF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000731">
        <property type="protein sequence ID" value="KAJ3213246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYF9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="140"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="189" mass="22323" checksum="727B18B615528D27" modified="2024-05-29" version="1">MSFIIVEIYDIMKVLNDIGETCNATKSIKNKHLTALMETVHQFQLFFKNIEENFTLMDTYLNETEKQEFKNEIIVSTNLTKQIFAYIITIEKKSYISLNQIKVKLTTILSSSKSLQIFVDCSTYFNKEKVKPGNTVYPIDERFMNQIKEEKEAMNELKRLRTEQEKNMKQFDKLLEDYKREKLIINSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYJ4</accession>
    <name>A0AAD5XYJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYJ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Velvet" evidence="1">
        <location>
            <begin position="16"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="82" mass="9400" checksum="1ADC989B44C32BB6" modified="2024-05-29" version="1">MTLRTLIRSSTKKETFTFSQKFNVIPPKYFPGSMVSSDLTIIFKKQGVRLTIKKQKKQINETSISDCKLVDTHDSGLDLFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYK6</accession>
    <name>A0AAD5XYK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000692">
        <property type="protein sequence ID" value="KAJ3213626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYK6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="411" mass="47403" checksum="4E4A1F0711AC22E8" modified="2024-05-29" version="1">MKIHSSQKWNITECLNCDCQVFASHISHSNEVIDNIILLGKDCLFSEKEIASAKLKLDYSKNLKIRLFEIKDDKQQKKTLDHNNSFHEDLDANSPQEISTLFPSNNKKNFINKKYTNEVTTKIYTEIDDICEKVLFYKLQEVDLKVNQFKEELKLNFFNEKNVLLQDKELLWERIKKKLDLKEISEEEFRANETNEVTEIQPNIPQLHSISDAEVTGALPIPTSSNEQHTSISASAPVLVRTLRPASKQPPISSLNSFSLTSHPLFLPVFEDEEISKNSTEDSFNKKVHFGDNKQHLSQNTEDDTDIIFNLDGYELTSNEKYYKILEEETPESPKLLKDNSEMENFNDIETYKIPTLVPSSLPVQIPGRFAIENLDKDEDEEDDDDDKQNNVDFKQKVFTSKVVNFGSKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYV4</accession>
    <name>A0AAD5XYV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cytosolic Fe-S cluster assembly factor NAR1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Cytosolic Fe-S cluster assembly factor nar1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Nuclear architecture-related protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004497</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYV4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000042">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor NAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3226617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="131" mass="14456" checksum="EEC62B2CC27861C7" modified="2024-05-29" version="1" fragment="single">MNVLIEDQFSDFVSPGQACINPVHINKSNSSKKRNIVLEDDSVFEMIDGKEEELEKVSITLQDCLACSGCITTAETVLISLQTKNQVLEILKKNEECINSGLMDDFKTVVVSISPQSRASIGAKYDLDQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ21</accession>
    <name>A0AAD5XZ21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006488</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000562">
        <property type="protein sequence ID" value="KAJ3215187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ21"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27000:SF642">
        <property type="entry name" value="INACTIVE LEUCINE-RICH REPEAT RECEPTOR KINASE XIAO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27000">
        <property type="entry name" value="LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="700"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3215187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="831" mass="94925" checksum="E6C294731BE6FBC7" modified="2024-05-29" version="1">MGRVDSLILTNKINLSQGIPLEIGNLVFLKTFAVNNTIKFPPNGIPANVFSNLVNMEVLDLSANYVFGSISHSIDFSKLKNLKVLNLAKNHFDDNLNFILKNLTNLVNIDLSENKFYFDDFNTAFSHMRSLEVLTMANGVLNKSPQALPLTLHLSLSLKTLDLWFCFNSLSTLPSNLKEYVNLQSLTLNGNNLYGSLDSLANLPSLQVLQIGSNHFEGDIPKFIVDLSLTSLDLSFNNFKTLPSNIAKLGLIEHLNLASNNIEHDLSFINSFNNLKTLRLSNNSFYGKVPSISQSRELEVCNVLNSGKSVCREPETFIPTNCLSWYGLQPCYTLSVDAGIGIALLAVVFASFIIYASYKLKKWVLKKYGSLRNHCNQKAAGTALDEMEAGRLKARNSFTKIKTLAKNKKKKYFSPRYDYDNCKIPILRFFMRIFLTLISLGYVVFLFESTMHPSRFMEDIKHETFYSAHTYVDENNSISHMGSSNIPIAVFNLNYELSPKSNAKPHCTYFKKGQKYFCHNNPNWYYQSNVFATRRYSNFSQSDLLLREESNFNPNYFLLGSVFEKLYEKTGEDDVGASVEAIHIKLNEEENPFIGGTVGLGHIFNLGFNTQEEIKSAELHKNLYTAHIVPNLTNIVKFQLTVFRKLDFTSGFLGEWDSIYRDIYVYQVFVEHQKSIRNDTTIILLPLQENAMIVSEERRFTIITVVARILTFFTSLLTFYWFLFGRGPFRPWGYIQEKFGLIRKVATKRKTKKGRNLIDWDLRLFLKMNNLTEKKNEKSNLNDQSSLEGIDLDSLNDSNVDSINVDQSDGKVQTIPKEKQQDYLESKSYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ54</accession>
    <name>A0AAD5XZ54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000194">
        <property type="protein sequence ID" value="KAJ3222058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ54"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="112" mass="12924" checksum="7962FF96176EC741" modified="2024-05-29" version="1">MEADIIPPQSDNSSTESIEALKAKLLSKKQELEKQKAEYSEAITKFQGDSVAIWDGIEEIKTNAKKHSLEDIQDEVEKHLNIKFQSIQPSLRRREVFQDLHIFDNDLKEEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZB1</accession>
    <name>A0AAD5XZB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZB1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="632" mass="71034" checksum="FCBBCF85C8B2D7DB" modified="2024-05-29" version="1">MNFTWRGQDIPLSVPILLANKKDLMIYSVTNDANSIGLSTEMTSKLNSRDEAWSNDPFSVKSTTGGVLFTGTSVQTVNTILIILITLLLPAIHKFVRAFLLSRGFITISILSESNTDDAIRILRKTNCSKDSKIFSLAMVVTLAITALLSSAVPYSTKTMIDVKLADDIFLALNRPNHTTFLKEGQQEFIKAKIIPGEVKLESSLDNKFLMNTTVGKVEFSAPSYSYDHQGEIYNSLDLTETLSNNGVKHYSLKFNANISDDIIPDIRSDGWYKPKIGSVEWINSIFSCRGKYGEDTQYLYDALTDTYTGYTHCFDKHQNVVSPLFSMRYVTSREKYEEGVTGLQNEIYLTDEVYFQYIIKCHGSDHNLQQYDSQRYTIDIAFSGNVKVTELTYEDSGVQCITTEIHFEIRGGKVLESLKALKSLEELDSFDPESFDQLEDTNSWSILKELQNIKENIPVQVVWNGSGDKARLEHFIGIDPDNIIGLHSAVRSIEENGAQDGVYLCYRGVWIHPLMIFSILFLLTIKILLIAIPVIRHCDVTTFEAILIVTSFINAKGINLNGNKLPEVNYGIVNPESHESHPAIGTSDSYLALRPGSLQRTTIEEVFKTNSEKLPHSTAEKLSYDTERDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZK1</accession>
    <name>A0AAD5XZK1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Scaffold protein Nfu/NifU N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZK1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000001">
        <property type="entry name" value="NFU1 iron-sulfur cluster scaffold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.70:FF:000001">
        <property type="entry name" value="NifU-like protein 4, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.70">
        <property type="entry name" value="Scaffold protein Nfu/NifU, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014824">
        <property type="entry name" value="Nfu/NifU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036498">
        <property type="entry name" value="Nfu/NifU_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035433">
        <property type="entry name" value="NFU1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF1">
        <property type="entry name" value="NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08712">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036773">
        <property type="entry name" value="HIRIP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00932">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110836">
        <property type="entry name" value="Hypothetical protein SAV1430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Scaffold protein Nfu/NifU N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="211" mass="23742" checksum="115601F9843B18CE" modified="2024-05-29" version="1">MLQRTEATPNKDSLKFKPSGKQVMENGGTVEFLTKKESLNSPLASTLFNIQGVQSVFFGPDFISITKDEDQPWQLMKPDIYSSIMDFFSTGKPILIEGGYQSPKDTIVLETDSEEVAMIKELLDTRIRPTIQEDGGDIEYCGFENGIVKLKLRGACRTCDSSVITLKNGIENMMMHYIPEIKGVEQVLDEMEELGNKEFKKLESKLEKKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZK3</accession>
    <name>A0AAD5XZK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RING finger protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RNF10_1</name>
        <name evidence="9" type="ORF">HK099_001782</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000154">
        <property type="protein sequence ID" value="KAJ3222897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZK3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16536">
        <property type="entry name" value="RING-HC_RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039739">
        <property type="entry name" value="MAG2/RNF10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983">
        <property type="entry name" value="RING FINGER 10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="130"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="960"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="960" mass="108006" checksum="838AF80C8B4730F2" modified="2024-05-29" version="1" fragment="single">MHHKNKSSNSSNKAGTHSKTKLNSRNETLKDVRINNNVIEEIRSSKRINSKGDASLLDFNIPPRLNGQTHKKKNGSSASVNKERFVNANYRFVVSDENTDYALNLIDPDLAVDWNKVIQVIMPTSDIITCPICLHPPTAAKVTKCGHVYCWHCMSHYLNDMNERSLKKSTKCPICYETVEANHLRSVRILFTKDINISKNNTIDSGEAIEKVKLKMSLMKRHNGSITALPRSTYNSWAKKTDSVFSTQNVPPCIKDPNALTFSKLLLCSKEYLREEILMRDKLELEQVLSDIAISNLNENSVPSTTEVKFVNYCLNLNNSKLTELNFICKEKWQVTPHLECNNKSDNLQSKLDYKEEHTVEKPQQFTIESNLKLEIKKKKLVEPYFYFYQSSDGQNLFLHPLDIRILLHQYGDYSKFPERLDVDITHLSESTLNQGLRKKFKYLGHVPLGCDIGFVEVDWQTFELHKDTIKLFSKEILKRKKRHLEKEISEKKFQERQNKRNELVAQQVEIENKENFFSSQRFIGEDSDLSSYGENENLFPPMGVASAAAESGVWSGASFGMEIKKFLYKRCSIKYKARITGTGSRFKNIQKGGSFRGSGVRFNVLNNETIVVDCPKKDVDDKDVFSEVVYEQSLNPLFKKEWTLDIGDLDEKQDEALVNELINLDLKERKAAQKFHRQCKNLGGDFHSALNKTDLLFLTYSDGKKAPVSPNAYICLSKKHNETSNLSDLYLPIPGTPPAYLEDGNIDSFKTDCIKACGNGVDFRFGAISLRQQTLGVCTCVGSWPTAPKLNKKSLAISVEPSDGFISGLQAPLSPHTYQTCAEFSQKFPTQGLGNMACPCKEFDYPYPDMGSCKWAGESQVVPVPGAPAVWQSLENYTPILGCPAAQKSCNAACGVTSGEFLASNVACFNFMSLTTIQMMCQCKDGKFPTAVNGFKLMSAMDANTGLVPGTSSSYANNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZN2</accession>
    <name>A0AAD5XZN2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000306">
        <property type="protein sequence ID" value="KAJ3220329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZN2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="27829" checksum="61E88BC3BE081764" modified="2024-05-29" version="1">MAATVTESQQPYASAAVRISFIKIIENNDINGLLDAYTHNPSPADIGRSFKYICELGREDLFKIVVEKSIDVISNWDLEWGYKLASEGGFKNLTDALDPYQQRIGDHHKGWAMKLAYEKDHIDLVKDQLQKYGGQINAQTKGWLVKRAAEKGDFSFLTILSQYKEEISAHDAGWALKLSSELGFVDVVKSLLVDYNERITPHDKGWAVRFALEKNHSETAVLIHKNIGASGTNDYNQWAKKQDVLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y094</accession>
    <name>A0AAD5Y094_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004452</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000314">
        <property type="protein sequence ID" value="KAJ3220130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y094"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032432">
        <property type="term" value="C:actin filament bundle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051639">
        <property type="term" value="P:actin filament network formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21300">
        <property type="entry name" value="CH_FIMB_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000042">
        <property type="entry name" value="Fimbrin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000016">
        <property type="entry name" value="Probable fimbrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000027">
        <property type="entry name" value="Probable fimbrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039959">
        <property type="entry name" value="Fimbrin/Plastin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961:SF18">
        <property type="entry name" value="FI19014P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961">
        <property type="entry name" value="FIMBRIN/PLASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="4">
        <location>
            <begin position="324"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="4">
        <location>
            <begin position="469"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="4">
        <location>
            <begin position="593"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="4">
        <location>
            <begin position="712"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="994" mass="112101" checksum="72312EDCBEDBEA29" modified="2024-05-29" version="1">MNKTINSADLHKFKQELSDDEWETSPDVEYQQPFNSKSFISSEETQLPPPKPPQYAREQKIDIEKSQRNSNNDNLKSNLNPSTNFNNISTPTTTPLYKKNSFVFENTTSVIEKGKLESLNNSSHNSIAPSAELDKKPSFLHSTSSNKASFSSTLSSKNSEPYKFTNSKSTAFAINSLFRSENNSVVNPSKPIKSSPAVFIAQQEQLYNMPNVNVHQLSSKYAFFTPSEISAFHQQFSTFDKEGRDSVHQRDLATVATKTGESYQAVVDKLNNLRITNDQGYVSFEGFLKAVTEVRVDKGVNKGGDKTKITLHGHSENTTHTINEDEKESFVHHINAQLRDDKDIKHRFPIDHQTMQVFAECKDGLLLAKLINDAVPGTIDERVLNVGKKLGVFQMTENNNVVVNSAKAIGCSVVNIGSSDLLEGREHLILGLIWQIIKIGLSARVNLKFHPELFRLLEGDETLEQFIKLPTDQILLRWFNYHLKKANWNRQVKNFSGDVKDGENYTVLLNQLKPNECSRLPLREQDLHKRAEQVLNNADKIGCRKYLTPKTLVEGNAKLNFAFVANLFNTHPGLDPLSDAEMAGIDDFDSEGDREARAFALWLNSLGVDPFVNSLFDDLRDGLVLLQAMDKVHPGIVDWKKVNKAPVTSKFKKVENTNYVVVLGKAMKFSLVGIQGSDIVDGNKLLTLGLVWQLMREHIVQTLKVLTKNGAPITDNDIVKWANDTVAHKAGKSSKMANFKDPSLRSGVFLCDLMNGIKKGIVNYELVTNGDSDENAKLNAKYAISIARKMASHLNVDTEKPLKRANTAPTKSNRGPPRETTEFICYAMFRVWHRIPPKTDIPPQLFNELVFIMHDLLCKTGVGMSCLLLALLYVARLRNATPDSEPILMGSEYRVFVCALIMAQKWLKDDRLSNTYWARTSTIPISEINIMERQFLSKINWNLNSSNEEFEKWKKVVKTLGGEHAQRLAKNKRERLDSIENQDHKNIKVDMDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0B4</accession>
    <name>A0AAD5Y0B4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000222">
        <property type="protein sequence ID" value="KAJ3221569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0B4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="38141" checksum="D7A1CB357ABBD141" modified="2024-05-29" version="1">MPNSINALSNLFSGTNFVSGPMVYDSRRDTRLDTARTNAARCEKELRKDRKDLEKKERELMTKIRNLERRGEHYKARVVAGQIAQYRAIGDRNFEAETLIQTRAQVMVSDHKVNRAEVEAIKGIKHANLEENHHTVGRREYKYAARMNEYEDMEVIMNSGMDDIYDEAEEAKPKFKHVNSEVDSILREVFSGKKECYDRKPTKFQAEKKISLKIKKFEHVFNSTSTLNLNDLNNAANEVARHHVQSRKTCPSGDFESENNEFPPAPYSGEFPPRSHSNRSSRTIRSNGVPLKIDTLDYSLGIKYRFNNFSNANRYVEKRTFEKLGHARGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0D1</accession>
    <name>A0AAD5Y0D1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000296">
        <property type="protein sequence ID" value="KAJ3220502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0D1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043226">
        <property type="term" value="C:organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="33"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="95"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="16055" checksum="C47B7D49C3C17212" modified="2024-05-29" version="1">MAFQAFTLFDKDGNGSIDYEELKEIFISLNEESSESELQLMINNIDFNKTGKVDFDEFIAVMETTKKNRKQQQNNSISQFHFQKLSGDENSIDTQSNEALVEAFRAMDADGNGMISPADLRSVLKGLSQDASAEKVCHFYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1M0</accession>
    <name>A0AAD5Y1M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000111">
        <property type="protein sequence ID" value="KAJ3223940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1M0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="108" mass="12369" checksum="4EC37D4523EC4C35" modified="2024-05-29" version="1" fragment="single">MIVLNSKGTISFKNGNSYSYEFPLFQLHVQKINTDVTRIWFSDNNRNPIPVPPNTLQQDGNGTFHNDFNGSFFLTWLGSHTITHNGIAIFQLNNQKKVAVHSSCERWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1X6</accession>
    <name>A0AAD5Y1X6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000092">
        <property type="protein sequence ID" value="KAJ3224461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1X6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="195"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="262"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="707"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="992" mass="115664" checksum="D264B9357155C947" modified="2024-05-29" version="1">MNTSSSSFNLNELSSLELVAEESDFANCSNITSGGQQSQLSFQVENNPSDINFYSKLNSNKYFSTPERKAPYLDEVTNTPGGGSYYLSESNTPHPSIKMSSILLQKKKNNNKKSTPLVVKSNFLSSNILDENLIAGFGKIVGEDLKNPNYNDSFLYGKSILNSAVNNSDTEWDYDMENEDPKVINEKYNMAMRSIRRLKKEIETISATSLELKEKNSELVEMLDKSQREVCKFKDIADKATKESNAETDYLKQEFEITKTLYADSLKQIEKLKINIDRYESNEEANIASSQEKRILQSENEILKKNVANAKAELKLKLENHLSEIEQKDMELAVFKNELNEAQISLKSLDVLNSISEELKVAVEENLDLKTKLKNLEFEVSSDREAELDSLKSTNVKLKQELEEVITLTEKKFKSEIESLKNCNDELKKNIDISETRKDFLINEQLKKIENLEDINANLLGSVDQLKCELEVTTDMLKKKSSLHLEQVNEINKNLLESENLIKKLTSEIEMLKLESKIEVNNEIDALKSQNRELEERNASSNSELKSLKETVELKLHEVASLKNEIANQSDDIVNQANKFNTQEENMQSLKQTNESLEKELSLLQDKMEMEKNTLLQEIDILKDKLKEHNIIIEKGRLEILEIKKKLEQREELYEQLKVINDSLNSEKEQLVYKLKTFTENENSLTEDLNKKVQYLNLKNLESESKLSEKEVQFNMIKAENEELKNNLILLEEKLRIKISTLEKSHEEYLIQSKLLNEESLLNLKKELEQKQAKLANLEIEYRKQMELRNQQFTEFETNFSNQLNQLLKQNEVLKNENFGLKVQNDETREKFTNLNITLVEIKSSENILKRENSGLLEKNENLRTIVHSKDNEIKKLLESESSIMEELLKVEEQITVLKQYRTEANKWREAHKSNKFRIQQFKLKWMLEKEELKEDFERLGYKYKEVLEHVETVVQFFENLKNSNHFEQEFKNFNYLETNLEFLKEKLNELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2L7</accession>
    <name>A0AAD5Y2L7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein pih1d3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PIH1D3</name>
        <name evidence="3" type="ORF">HK099_006278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000053">
        <property type="protein sequence ID" value="KAJ3225778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2L7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00298">
        <property type="entry name" value="ACD_sHsps_p23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026697">
        <property type="entry name" value="DNAAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041442">
        <property type="entry name" value="PIH1D1/2/3_CS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21083:SF0">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21083">
        <property type="entry name" value="TWISTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18201">
        <property type="entry name" value="PIH1_CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1D1/2/3 CS-like" evidence="2">
        <location>
            <begin position="68"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="168" mass="19469" checksum="BF64AC7D20017C43" modified="2024-05-29" version="1">MNSDFSSLTELFSTNEKQLKKEKEQIQKEEYLKKNIKQKSTTQNKKDIWEDEEIVAAEEAEELNDPRSQPEYDIAYRQTVSSEDMFLGMSGKLNSISHSDFLVVTIKLPGVKFKEVQLDCTEFKIDLRCPIYKLNLSLPKKVDEKKGDAKWDSVKSILKITLPVINEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y361</accession>
    <name>A0AAD5Y361_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005875</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y361"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="339"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="398" mass="45033" checksum="4AE6BB8B5DFB8A39" modified="2024-05-29" version="1">MSNATVEKPVLKLNIVVNNTQSSPLESNSSPSVSPTSIYLTTTVTVTLDTFKASLMPVPKSPDTSKMDFNEKELKYYQLEIFCAIIGILFLLFTLIFFTLCLLKKRKRNCLLSKNLQTESQLFDSLNSRSRPNQYFWQRKKFKESSLISSPSCKSIKPTVASSSLENWKLNGDDILENAEFNEFSEDSILIQLAAPQKCKVLSDTIKSLNRNAVFDGKILQETTHQRYSSSPTSMENYASDNVFLTTMERNSYLNSCSEQFFINTLERNYSKSTSMISSSPSNLRSDSTSTIKCNDLISHQLLDKISLISVGMQQTTKDISAKKKKPKKKLPADVQKFKLGINYRAQAHYLPRMDDELKIKKGDIIMLEHIYPDMWGVAINKTSGKKGIVALEFLTEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3M0</accession>
    <name>A0AAD5Y3M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CEP135/TSGA10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051877">
        <property type="entry name" value="Centriole_BasalBody_StrucProt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20544">
        <property type="entry name" value="CENTROSOMAL PROTEIN CEP135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20544:SF0">
        <property type="entry name" value="NUCLEOPROTEIN TPR_MLP1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="154"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="519"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1335"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="369"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="437"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="555"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="637"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="777"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="921"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1131"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="160"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1345"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1366"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1399"/>
            <end position="1417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1428" mass="166467" checksum="7F5C13B2CE51A13B" modified="2024-05-29" version="1">MNDEKLKQVFYSQFNLVSTSEDYNIRFDDWYQKILAQYNEPHRFYHNIFHVKRMLMQLNHQELNNKPLILAIFFHDVIYDPKRNDNETESIKFFYEFGEELMADSVTLIAEVALFINCTIKHEVTACSKKHDLEAFLDLDLSILGSSWEVPYTMPRSRRSSSPAPQRRAAPAAPAKTQPQNSSVPAHQPQQPGVGIGSVVGHGMSNMLFGSSSSAAPVQQEPQQQQYQNNNPYSGPCENDQKAFMRCLDSNPHDMNATERDRRNQQLSKKQQDEYEDLKFVNSQLRQTIVNEKEKHEKFREKIEETLTRQGIITEKPKKNKAPLFNSQALQKLQKIDIETGLEKMDDIIDFPEITPIVCDLVKLSEQKVEMVEKDLFSLKNQNSSLENELSLLQDKIVKKDQEIQRLGIQLEISRSQQWGGSVDLLTSGSSLEINDLGLAKRRIDQLEMQLEQLQEHIQLLEADISKFEEEKKLILESCDDERKLVENDLEQEKIKNGALLKNLSKLEIMVSDLDRIKNSSSPMKNKLKNSYSNQENSLQPNNASQPISKNIRQLSELQSKLGTCQENLKIKNERIESVKLEKTKLSEENNLLKNKVIELEKKKATVLEKKKATLIPKPTVESNFQSSIPVPTNSNVKKLEGKLKTLEEEKLTMESTIKTMLTEKNSDKNLLNERVLEINLLNNQLENFKYVNAESHKKQLDLESSLKISENEQKKLVEALEKFEDFLSQINVEVEIVTSERDNLSRLYQQEIIQTSIASIQTDEDNQKDIERNNEIKELNNLNKDLLDTNNSLKNENNYLKLELKKTKDDIEKQLYRQEETGSSALEAIKQLETERDGLKMALDSKERDMLLLVDNCDALEKHIKRMKEDIESFENREDNLKIKYRQLEVEKEKEVFKVRQLKSKISELEGAKERNYTELERIKIQFNAAEDQILKQKEMLEEVDRERDLFLLEMDQKDEILNEINDKYQALDSEKSELEAELKYLKDLNENFNQNLNDLEYELKTLRLSCENLTAEKDQLNLESSRNAEEAKNVSSDLVVVARENQILHQSIQEITNERDKTKDELIDMERYLHNLEDNFNNNEHEKENLFNSYRKLISDFEKLDINFKAKLEEENNLRMEVLMREKRIDLLQKSIEEVGAELNQYKIDLRAYEKQTTLLTRSLATAERTISNLEKEKTRLSREVLTTRDLTTTIDKSKEEVQSQLLTLKIENENLLKELKNFETEFEDQNKLIQLEKQRSEKFEQLLNSERKKNIQAEKDTKDLEFAKNHFDQQIQKLKSQNSIVLSKKEILIKEQTLEIEGLRSRVASLIETVEKQKNEIQELNKKATVSISKNGTKDNETSQQQEMPTNISKLQLEQEIAENSRKMKGYEKSQIKEMKGKYQSRREEEDNDDGVEAKTPETVNKPESKKEEGETLQTILDLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y4A5</accession>
    <name>A0AAD5Y4A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002904</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1089"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="322"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1157"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1099"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3228399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1463" mass="171307" checksum="DADAB95AD6BEB2F0" modified="2024-05-29" version="1">MDDPDKSKEKELEEEEDLDYIPDLASIQLPFDDNTLAKTFETGLDSLESWNEFIEFVSGRDVELKNYKDELHYGDTPKTSDPIVNRGRRASADSQISPFKAKSFEEVDASAEGIKGEILRQRRASYNKISTSQRSFVSLLSSQSNKILKSVGSDLLHESSNPTLRETNSSQLNVNEFGFEENTLINDKPTEKFMEDELDLEKRLRELDDKYVMEEKLLLSLENENKEMEQRFSRRSSISSGTQIISRSASKHSNLSYSEIEVTEVDTKKPENNHSWQRSLPLINKENLELDEVMESEFENNTFLKKSSYFNKSCDSLETIMKDSVANQLKAEELEKREFLEKCQKLHSEEIALESELDRLLKSLESEKKKFEKLTYELEIFNANRGSYIRERKLLKSKIRLLQDKLKTIQQWIKIEGKGIFSREKDRATILLQKAQKILDQKNSKLVEIKKRKDHFMAISNNKRIVAVQVMTKSSELKTILNKIRQENIENCATIEKTETLIVEKKASRERQLLNRAQVEENRRKFEFDLLFQACNHQNPNIPLDFDQLRIFNINSMNLTRLPDLSPVPNLRFINMDHNAFTNLEGLNPVADLNYLTLNSNHINKLDLVSVKNIKHLEAAHNHISNVLGLANCKYLKWLDLSYNPIRSIDFLKEALSLKVLLIRSVMVPNFSSLSNLKNLMALDLGGNHIYNDPLLMIKEMHILQYLALDENSYTEVPDISNAMLFELRLEKNKLRTVNFVSFLPMLRILHLEHNSINNTTPFSMLPNLQELYLQENNLHDISCVYGVAICRNLKILDISKNPVSYNADLEIIIFTLFRQLKYVNGLTFREFFSGNDDFSWTNPLKQLKHLNKCVNYLCPFVGDWESENQRYIENDDYYRIHKTHYKSIKSYLGKYKPPYITFLSMGGEEITEENILMEVQEKNVNWLENTSHQFQIELKNLYARSPPHSDICLLPAITKFKDIAIFLQISYVQACWRRKMAMKAKRKRMRAILCIQKSWRAFQQQKIFKLIKKLRSEKVEKAAITIRRYWKGYKARVLLKKLKHQVFLNQPIPEDENLDNWVSETFETNFELRLDDYLKDDLKITEEERARSSRSPRRSTEPEKHRISKEGDAVTLEESFHSEKKSTETEIEFVKKENLEKNLPAINESEANKSGIKEQTEEKVKLESEEKVLDVKEEKKKILEKFKSEEEERQRKKKVIEENIKQINANLEKKNDLVHEKIKAPAKKQIVTEIVPEKTELETEIEEDWGFKGELFQETLNKNKKRYANLKNISKKRTLMNDPNERLKVFQKQKDNRKVVYIWDSDTEKEMQVNNFGKDSVSLPIIPPEKLPKQMPLPLTIKSNHNKFWNAQNNMLDSFQSYNPTGSDKYKDYHTDIHNYNKKITDHSQYAPPTGISPKVTLLLNNYVATKLLGNNKAEFEKKGSYYKKSKNSDNEICDIKVRDDDKELYYNDVLKTNNYNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSZ9</accession>
    <name>A0AAD5TSZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Epoxide hydrolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003119</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002091">
        <property type="protein sequence ID" value="KAJ3199535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097176">
        <property type="term" value="P:epoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010497">
        <property type="entry name" value="Epoxide_hydro_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661:SF35">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21661">
        <property type="entry name" value="EPOXIDE HYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06441">
        <property type="entry name" value="EHN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0058">Aromatic hydrocarbons catabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epoxide hydrolase N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3199535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="177" mass="20757" checksum="AC2824A8976C4B7E" modified="2024-05-29" version="1" fragment="single">MDKSSIKKYEFKFSKEEIEKLNQKLNLTVYPDETTDSDNFFKIDDLKILINQWKNLNYDRVEKIFNKFNHFHIHPVDDTEFKLHYIFLPNHTPGSKALMLVHGWPGTFFEVIEPLHKLGYSVVVPSLPGFGFSSIPKKSGYGVKRIAELFHELMITLGFNEYFVQGGDWGSFVTRWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTL4</accession>
    <name>A0AAD5TTL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MHD2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001745">
        <property type="protein sequence ID" value="KAJ3201328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014772">
        <property type="entry name" value="Munc13_dom-2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51259">
        <property type="entry name" value="MHD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="135" mass="15454" checksum="B4D2E166B8B1E060" modified="2024-05-29" version="1" fragment="single">MAKVQTSMKKSSSNHSNLSQIEVEKVEEDLNSIFTFLNGNLGEITSFLCEDLSLKLVYKVWKRVLVSIEGLLVSDLEEERGVENEEEKDLEIKLWDEKRLSFIKVTVELLITFFQGEEGEGLNKETIQGTKNLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTR8</accession>
    <name>A0AAD5TTR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001672">
        <property type="protein sequence ID" value="KAJ3201789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTR8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="281" mass="32217" checksum="30AE7D101A1366F0" modified="2024-05-29" version="1" fragment="single">MTNSFTAILNNNPAITLPKNITIEESYNDNASNLSAIAIEKLGDGSSTFATSLSFSVVFPMIFLVFILILAAYLFYRREQMEGNTFTIRKKKKKTVKNLEKNEMVDLEYNKANAEDDSYTSHQKIFFDSNLNPHRFHNETMIIQRDIMSVGFKNDLSYNNAILECYSTTRDDGFVFEQVFEFKEKNVNGYFTEVVPEQTNNSTVSTNFSTSTIFNNTDHVANAEAKILSLPRLSLYPNSLQRLTNKSEVGSILSNSLKYKKRLSLSDEYFNGQNFQYFTDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTT5</accession>
    <name>A0AAD5TTT5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001607">
        <property type="protein sequence ID" value="KAJ3202198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTT5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="60"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="234" mass="26713" checksum="CBA2E1303330CF04" modified="2024-05-29" version="1">MSTDFDIILQELDVEILNLSKKTSQQQISSQLNLNNHFSNHTHYSKHSKSFTLESISILHDAFGGWLEKVSKSKFLKKENLKKKYIILANQTLYIFKTNDFKSSFEAKYPITSKTVVTKSLKPNQEYTLNFFTEYQEALGKLSSTNVEDDEDDDVLGLGIVGLTNTLQKSIQFKCKDEFELQIWLDLINEAIENEKSISINNNNSEDQIHKPTQRSFSISSSSTHATEDSAVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU50</accession>
    <name>A0AAD5TU50_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Receptor ligand binding region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_001573</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001459">
        <property type="protein sequence ID" value="KAJ3203213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU50"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Receptor ligand binding region" evidence="9">
        <location>
            <begin position="3"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3203213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="420" mass="47404" checksum="81E48E61BA35B24B" modified="2024-05-29" version="1">MNEVEQIKNSYARIIIVIVYNLDAIPFLRDANKQGMIGPNYVYLGTDSTSDMEGFVQDPIEKTYFQGYIAITAYDRVNTEATTKLNETFYPKFKDRIPNQSGFSHDCILAFIYGFQNFLNTTNTKIEDYKHLKPEDRVTLKNIQNITFEGMSGTVAFDSNGEPRSRLYMIKNYIDNNMTTVFIGTIDSGGNDRMEIKLQNSVVFNGFTTLIPSDTAGEYYIKLNDPGTIIVLWSVVGRIILTVLFTKIPESNKLMMSRKKLGQQNSKSKALKSSNSNDNLNVSILKAAKKTSIFTVMAKNESLIFSAWKSAKVSINEFNFSIHYLNEKKKFLVQSEGVSISLNDAVIEELDTDTFRIISIKTSFIVLCTDESEKKALVEQIKLIQLKETEEEDNDALYSKAVASEFPSAHQSGFPLNSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU97</accession>
    <name>A0AAD5TU97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EIF3L</name>
        <name evidence="5" type="ORF">HK099_001085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001284">
        <property type="protein sequence ID" value="KAJ3204588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU97"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3204588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="502" mass="58258" checksum="FD6E5C6687054800" modified="2024-05-29" version="1" fragment="single">MSGEHLDDVDIELNVYGEGDDSEFVDDAAESYIETSDNAFLNEPVKNFIHYFYKNFQEKNVWGLSGLYMQTFHKITERFFKTSHWPDVKLIAKEVNNEQGVFQYELPNQWLYDIIDEFIYQYQSFQQYLRNKKKSKEELELLKKNFSKISSNDSRPCWDVNYVLSTLNEVVTISNINEPLTAGNENQDSNLGGSEYSQKSFYRMLGYFSLIGLLRLHSLFGDYDLALKVDTLENVQLTKKHPFSKLVVISRVSTCYYVGFSYLMMNRFSDAIEVFLNSLSVISNSKFHNKPGPHTDAITKMQEKIYFLLAICVSLSPQRIEESVHTVMREKVGIDVFIKMQRGVEDTLNDFGELFQKSSPRFISPVLPNFDNFSPLPNPGDYQLKIFLSQVKQHTKMSVVRSYLKLYTTLDLTKLAEYVDSSPSDLRTLLLSFKHKTINQKKVGLIDNAPTKASGGFFDGEYNNSLNNELDFFIDKDMIFINEFKQKKNSADWFVRHIVKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUG8</accession>
    <name>A0AAD5TUG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Argonaute 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AGO1_1</name>
        <name evidence="3" type="ORF">HK099_000697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001174">
        <property type="protein sequence ID" value="KAJ3205805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUG8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="1">
        <location>
            <begin position="223"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="530"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3205805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="856" mass="96235" checksum="CFE61200B127FD6D" modified="2024-05-29" version="1">MSKLRVGQEAVINVDETVKGALTHIPRPNFGRLGRKITVIANLYKVSIPDRDISRYDVVVKPDKVPKPLCRKIMEAWKNMDHSATLGWASKDRENAQYSKQLFDLKNKRTFTLSIREIKPVNMAVLLEYLSPSPKAIEIPFEAVSCLEVLLRQSPGLRFTSNPAGRCFYSDKGVSQLPGGVNVHYGWYQSLRTSLGIQQQQYTYKELLLNIDVVATAFYQQGPLIDVITNFFGKRRIEDCQKLFTIKNELRKLDKFITGLNIKISYRNTGRRKYKVKGLAAQSVRDTKIRIKEDDGVHEVTTTVLEFFRKTYNYNVKYPWLPAIVSGANNVQIPIECCVVLPNQRYVKKISEDQAADMIKVTAVFPQKRKERIQDGLNQLHGNNDERLLARWNVDINQNLKQVEARILDTPSLMFAKNKPQKVFNNGSWKTQGFAKPALLVSWSIALFGGAFGRPGSRDFGVLDSFMNKLGNELASQGVEVLWPDTTEEMTVLEVRGDIRQTLVNAKKRAAEIGQKFAGAKRTNSRSVDLVLCVLPQARNTALYNEIKRIGETDLGLMTQCVVQRKVADQKGGYLGNLILKINAKLGGVNTYVSPSDIPLNTGSRIPTIVIGIDVTHPPAGVTNGISIAAVVGSVDSGYAEYRCSVRVQAGRQEIVDDLHDMVIDLFEMFRERSKGVYPQRVIVYRDGVSEGQFSEVIFNELKSLKRAFVTLKMNKAPTVTFLSVNKRHHIRFFPANQKDGDKNGNVMPGTVIDTGIVHPYEFDFFLNSHPGLQVTFCMMKTDLTQIHCKTLLINYAISMLEVSIVPAAYYAHLVAARARAHVEKDDGYSDTASQMSENLDASKILREISNSMFFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUK6</accession>
    <name>A0AAD5TUK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001290">
        <property type="protein sequence ID" value="KAJ3204533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUK6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="388"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="615"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="794"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="483"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="930" mass="101473" checksum="5C7F04D9384279B9" modified="2024-05-29" version="1" fragment="single">VYEQVLLSTDPVKPKIKMILTYDSPFFGLHHKVFTTAAGEHAVSLVTSYWENQPSISSSISTSVVSAIPGVSLAKNTAYLASTAYSTGSYIASNTYETVSPIASSALSTGSSLANSVFSSSASLAGSAISTSASLAGSAISTSASLAGSAISNSASLAGNAISTSATALSTGATLTGSALSIGSAVTYTALSTSASLAGAAISTGTSITSSAISTGVSLASHLPGASLATNLTNSLSWKSNKTNSNGLRVINIDDDKDDVEEGTQKKNDTKKTKITIHHQHSQQEKKNEIPHPNQDTKEFDLNLYKEDLLKKRKESIESTTFNEKNNSSIINNTVTEESAEKKINTPKSRRSMIISSAAANAHAAISLGSGLASYAYSWGNAWKPLRGAAPSTDKNVNEEKELKKDQNGNEVKKENENELTKDQNENELAKDQNENELKKDQNENELKDEQFQNDKTNKKPESDVQSKLSKVTKKYVDSSLTDFDKKNNTTEEEHNIPKKNNSDVSDFENIKTELQQNENSLAGLTVKTSEEEDVKLNKIAQEIIERENLENIEDIQVEFDKDTIDLIKKSIFKDEVNFELKSGEMVTGLDIYSSPTSPKITDDDVVNNTAFFSNTNEKNTNIPENSDEKTKKNENDDKVSGVSIEPISYTRIAAYAGTAALILGGGYYVGVGGLIYYGVTNSFVRSAATAFAIHQAREIGSHFQFLYPLWGSSKDLNKRVNNLKMDVEKSGGIKFHGFYIRLPAKVVVVEERVKIVEVNESKVNQVKCDKINEVEDCHKTEVNDGCSEKIMKVVESETVVKEIKDENEEITDEKEEITDEKEEITDEKEGSILMCEIKNEDLEHEKCEGKVDESTIRKKESLEKIKKEKKTLVDRYFCVPPPDEYKNFFEVLDSNYADALCNSCRVAVGIAQQPSSGVSEVNVTKNAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVH7</accession>
    <name>A0AAD5TVH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002115">
        <property type="protein sequence ID" value="KAJ3199436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVH7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="124" mass="14314" checksum="FC3360BC9BF7F8AA" modified="2024-05-29" version="1" fragment="single">INQKKPDPLFLDLQFNSNFLNNNNQLNLSNINLTYEPIIGSIHPPQNSSSFHHLFEFDDALVNSPLINQISSQVCTLLTDNNFNTKSNDEKKNENRSNKPKKLKTNNFNDTTSNEEDEEELEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWA4</accession>
    <name>A0AAD5TWA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000819">
        <property type="protein sequence ID" value="KAJ3211682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWA4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="930" mass="109347" checksum="335C1A38B261360E" modified="2024-05-29" version="1">MIKIFNLKSILKIKYCVRFKSDFLIKSNAIKSKRFYTGESQIGTDEEELRHLQQKYHDIIQSTESKSQSTNPKQLSSYKEVFKKLKIPFEVNKNDQNEIFNLDIGSQSNTFVRTSKSVPSSDLSILTKKKGKRRAETKQFYNDKWWYSDLNLNDDADYVNILYIEKVNLVKFQNLYNLIKSENLNVQSKKKNQNFDIIKNDLQLFLKENKSFLLYYLNKDQIFTIYKTVILNFRKLSITREDIHKFFKIFLSNYEFNKRSEVKKIDENRCLEIFVDMKNIGIDPNHETFGLLFKAFKNSPLNLQKIHSYIMVTTLKIFQPVFKFLYLKGRIHEEKELGEKFSDIVSEKTFLSLLAGAVLSAEKSSNKLNLDLIQNIFYDLKTANIDLSMKLAVGLIRGFQLMDKERGLKLLMKLHLIVEQRSLKFPWNRHLIDALMEAYAGFGSHNVVQSLMEKQKRICIPSMENYQALMVSHTQAKKPVHYIFELVSEMELKNIPRNDVINEIVLKACVGAGNLDYVKKTQIYFQSYIENSVLTAVKSVTEQENFLTTFKKNMELMDATNIHLEIPKFSQIFKFSTTKTHFNLIVAFCKLGDIGSSLKIFNQWKEIRNWISEVQVQRDALYQKFLELEKKVSLLRKKQIIKLQNKETNVDDALQQENIDDEDKNMTTSYPPPPLFVLASIVRLFGVKGDFSSCKTFFQEEIFNKVVTRNLFERKLEEMVPAFKLKQEELENDLNLEIKKMRRVNKYAKPEVITKAISSSTKVEHLEVKLKSLKKNFFRLNLIKGENFNIGERGLFNYIYSEYNLGWKQNLTLKFKVDEENEDINNEFGDWKYCSNTIKSLPKLEVNSFDEGIMKFESEYKALCDLEFDFFFKFQEEYFNEAEKDDEKAFHRSKILNKIIDFTPHLSEKEIEDIIDNSELSVESKLQVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWH8</accession>
    <name>A0AAD5TWH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LUC7_1</name>
        <name evidence="3" type="ORF">HK099_000584</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001139">
        <property type="protein sequence ID" value="KAJ3206222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWH8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3206222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="297" mass="34760" checksum="05C95A5F8C68337C" modified="2024-05-29" version="1">MAAAQRKLLEELMGSAAIGGVPDLSNFRDEKICKSFLCGLCPYEIFTNTKADLGPCHKVHVEKLKKDYEKDLEKGGKDFLREFLSDLRTFIGECDKKIRQNQSRLDKTPEDKRVGALVNEIADLANEINTINKIVESLGEEGKVMDALAALKKADELTVVRSSKEAELLNLTQGGNPQANKLRVCEICSSYLSIYDSDRRLADHFSGKMHLGFLLIRDKVKELEEKLASKDEESRSHRDEKRDSEPRKHDDRRDRDRDRERDRDRDRDRDRRRDDYRRDDYRRDDRRRSRSPYRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWM6</accession>
    <name>A0AAD5TWM6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">STE7_1</name>
        <name evidence="14" type="ORF">HK099_007222</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000683">
        <property type="protein sequence ID" value="KAJ3213705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWM6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF9">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="115"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3213705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="486" mass="54945" checksum="8461C35074291978" modified="2024-05-29" version="1">MNRPQIKLRIPRKTTDGSMSSGTPVSGSSSLTNLKIDGEEIQKFKSEPDLLIENSENKLEESLIPIKKVDSIKRTLSVTENRQEQVLNEILHNESKSINNGTQIKEEDVSENSFLDLGEFLGRGSNGFVKKVLFKPKKIILARKYLEFTTDDDEGKEAKKVILKELNILRKCRSPYIVEYQFAFSYKGKINILMEVMDMGSFDSILQKLGKFDEATIAKIAVRVINGLAYLNEVHKIVHRDIKPSNILLNSKGEIKIADFGVSKELVDGTVDGTFTGTMKYMSPECLELKKRKESRSNFKGDIWSLGLTLMEFGLGKFPFPKEGEEQLEDTAMDLIVFITTEHIGLPKASFSKSFEDFTDLCFNCQSNQIETLGCRQVFSFKRVDVFSQLMWIPGCADYANTALNLNVLPACYNFYPNDSIISVVDNYLFPDNNDSMGDNVLDSNQRIVDHIVYINKKTNPNGASTFSSNNVIFFITFLLFFTLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX06</accession>
    <name>A0AAD5TX06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alanyl-tRNA editing protein Aarsd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AARSD1</name>
        <name evidence="8" type="ORF">HK099_007274</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000694">
        <property type="protein sequence ID" value="KAJ3213602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX06"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002196">
        <property type="term" value="F:Ser-tRNA(Ala) deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051335">
        <property type="entry name" value="Alanyl-tRNA_Editing_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462">
        <property type="entry name" value="ALANYL-TRNA EDITING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43462:SF1">
        <property type="entry name" value="ALANYL-TRNA EDITING PROTEIN AARSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="461"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="464"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="478"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3213602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="806" mass="89508" checksum="1DF366539A0A1369" modified="2024-05-29" version="1">MVNTIKVGDLKCQHDPYLKDFEATVVSVLPNNILVLNDTILFPEGGGQPYDTGSITANDITVKVTKVLRKGFIAHHFLEKELVGIQPGDQVHVKLDWNRRYDHMQQHTGQHLISALVKANFGWDTVSWHLGSDISTLDLNTKSITTEELQIIEDKVNENIQKALLINLHLVNKNENETFRPSGKEVPEELREGTIRMIEIESVDKNVCCGTHLSNTSELKFLKFSLVEKCKGHVRLNFIIGNRILSQLSELLAREKALTNILQTNPSSHAKIATGLISTSKQSLKSIKSYHQEIAYFLSESMYNFIKKEMESKNNNNGDWKILRLPNEDTIKLKNQESNSNLNVGSFEKNYKEEGVFSICSNDLSYLEKEAKSLSEIVDGKGAKLNAGNDMSLKMSAKFGHLNLTKFLLINGADPNAKVVLKKNWYNYFFSTRLYKLGGTLLNDDDNVDLNIGSSNLVGRINETRNNQTETNSPNVESFSNTPTSPTSNFNAPLLPNSETVSTANPQHNHILEASVLNKKKKVCQVDLLLQAVQGNHVHLVEILITPTKKNNSFDNNTVQIPIRTSSLSPTSSPTRIVNTEGSTSLSINIGHNEFSQDSQRVSSDTLQTALADAFLHNRLHMAKMLIKVGGAKSNSKMINNLLQKAGAWRLGCGVREKYTKLLVLCIQALTEETFQRLQHSIVRAVSEIGSVGALKASLERGGDINCWDGLPIYSAVYSGILGIYGGGIIVTSDPSDPNAGTSVSVAELSTMAVPAIAALVVMYRLVPFHRLLYSLILVCKEQSKRNRDRWLRLESPVPMNEVVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXK4</accession>
    <name>A0AAD5TXK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-dependent RNA helicase mtr4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MTR4</name>
        <name evidence="11" type="ORF">HK099_006682</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000594">
        <property type="protein sequence ID" value="KAJ3214758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18024">
        <property type="entry name" value="DEXHc_Mtr4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000003">
        <property type="entry name" value="ATP dependent RNA helicase (Dob1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000083">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000141">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.300:FF:000001">
        <property type="entry name" value="Mtr4 exosome RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF7">
        <property type="entry name" value="EXOSOME RNA HELICASE MTR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="133"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="398"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3214758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1028" mass="117607" checksum="2CFD845B2FC960FF" modified="2024-05-29" version="1" fragment="single">MDFDFSLFEEDENSKQLENQPTSFQYKRSLEDGDQNLIAKKRKEIELNKNISSSNIKVTEENSITVEKDFKAAGTLGSAEVDNQAQLKIVHNVKHQVALPDGYPYIPISQHKRPDKPAREYPFKLDAFQETAICSIERNESVLVSAHTSAGKTVVAEYAIALSLKNKQRVIYTSPIKALSNQKYREMLEDFGDVGLMTGDVSINPNASLLIMTTEILRSMLYRGSEVIREVAWIIFDEIHYMRDKARGVVWEETIILLPDNVRFVFLSATIPNAMQFAQWIVKLHKTPCHVVYTDYRPTPLQHYLHAKGNNGIHLCVDEKGVFREENFQKAIGSLQDNQDQERGRAKKRNWKDRSGAGGGTKEQTDLYKIIRMIMVKNYHPVIVFSFAKRECESNALQVSKLDFNDEKEKEMVASVFNNAILSLSEEDRSLPQIEHLLPLLKRGIGIHHSGLLPILKEVIEILFQEGLIKVLFATETFSIGLNMPAKTVVFTNVRKWDGKETRWLGSGEYIQMSGRAGRRGLDDRGIVILMLDEKMEPAVAKGMLKGEADRLDSAFYLTYSMILNMIRVEGAFPEMILEQSFFQYQTCSKIPELERELSILEDRKEKLMIDDEDQVARYYDLKQQLNQYVRDFRDVITNPNFCLPFLQPGRLFKIVVDSPKEELSENRVDFGWGILVNYQKRLPHVKGQDFSTAAEGPTFILDVLLYCTVDGEKPRPCVEGEVGEMVVVPCSLSSIDAISTIKINLAHDVKSAATRNNMFKTLKEIKRRFGNNLIPRLDPVNDMGIKDEGFVKLVKKIQILESKIYTHPLRDNPRINELYEQFLSKQILLGKIRALKKQITATQSIVQMDELKCRRRVLRRMGYINEQDVIEMKGRVACEISSGGFELLLTEMMFQGVFNELSAEQCAALLSCFTFTEKTDVSEDRLKQELSVPLKVLHEQARRIVKVSIESKLQIDEEEFLQSLRHELMDIVFAWCQGASFAQICKMTSIYEGSIIRSIRNLEELLRQMCNAAKAIGNDMLEAKFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXL4</accession>
    <name>A0AAD5TXL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006893</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000624">
        <property type="protein sequence ID" value="KAJ3214401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF9">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="18"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="113"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="235"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3214401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="31310" checksum="1EE3A4E5EEA8AA40" modified="2024-05-29" version="1" fragment="single">MNEPNPFILYSKNFVSSNPVAISATAAAVSSVLFGYPFDTVKTKMQAYKYSSTLNCIKQTYNGEGIAGFFRGVFPVLFSASVFRSISFTIYTRTKEFSMQTLNKSTNLSVLSKISLSSLSSGLFSGTVISCLNAPIEFVKIQKQLERIYPANVNSFGENITSSLETDAKGIRRNLGLSNNTTTYQWVVKIFQKRGLFGLYYGAHLHIFRDALGSSLYFCGYEITKYALTPSGERPSSITTLLAGGFAGSSCWLILFPIDLVKSNIQKEALSSSPKYTSARHFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXM8</accession>
    <name>A0AAD5TXM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000881">
        <property type="protein sequence ID" value="KAJ3210598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="Toastrack_DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4097" evidence="1">
        <location>
            <begin position="46"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="356" mass="38877" checksum="4097623719C6271C" modified="2024-05-29" version="1" fragment="single">NSQSSGCEIRNSGGSIYLDGCNLDRCELFNKESPIDATNCKFVDFVTAENGNASINFKGCNAGKVEAKNNDGSINVNDSSKFTTLNLKTKTGKLVIDNCTSEKTEANLKESSVNLTNNKFLEHLKVTNKGGNIKITGCESLMVECSTTEEKIAIKDCAFKVSTLLKNSNGNILLENLYSNIVDSETKNATTSICKAKLDGLKARNKNGVIEIEEITSSITVLETSYSSIKLKGDNNNFKNLSFNSNNGTFVGNCKILEEIKGCSSGGLISIERLEMGDISRVYLYDSSIIDVGLENFKGELLIENQNGVNTIKNEKMDLVFEKENGGVLKGFVNGEKKLDQKVYLRSENTAINFKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYE4</accession>
    <name>A0AAD5TYE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA primase large subunit C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007632</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic-type primase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000759">
        <property type="protein sequence ID" value="KAJ3212908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYE4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07322">
        <property type="entry name" value="PriL_PriS_Eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058560">
        <property type="entry name" value="DNA_primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016558">
        <property type="entry name" value="DNA_primase_lsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537:SF3">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26466">
        <property type="entry name" value="DNA_primase_lrg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA primase large subunit C-terminal" evidence="10">
        <location>
            <begin position="308"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3212908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="534" mass="61714" checksum="8F4A6D9FD630B6AC" modified="2024-05-29" version="1">MTVEQQSVKIINDPRVVGYPNRVNLYTFPPPYQLNIEEFETFALDRLTILKAIETAMVRNTLKSKDNKGYNAHVLKTIKEHLPLGRNSLISKNESSIKRKEMKKIFFEERKKDHISHFILRLAFCQTEDLRNWFIKFETELFKIRLTEESPEDQEKLMKLADFGGEVINLATYNVSNPNEAVSHKNLQNVIKIYYQSDIKDSNEMNQIFYKVPFEKVIENVRQRNLIVHNGFVYVPTNLTNLLLINLFKEKLTLELTLLLKNLPMLDDSNFLVSPILISLSKQHLSSSKVLNFNNDSNTFSHGDIDGLAQKHFSPCMKNIHDKLRHNSHLRHFGRLQYGIGLPYEESLTFWRKAFKNMSDDQFQKGGHPYNIRHSYGLEGKRQNYSPYSCLKIITSNSPGSGDHHGCPFKHFSSENLRPLITEMVCSSSSYSSSSNQVQGNVSEVMNLAKAGHFQVACTRLFEFTHQKNGVLSETIDTIEHPNQYFELSFRGLENKKTDKIVNSSDENNVNQNDMSNIEKEILEMRNSEEMDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYH7</accession>
    <name>A0AAD5TYH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000487">
        <property type="protein sequence ID" value="KAJ3216261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYH7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF37">
        <property type="entry name" value="LD47843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="50"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="131" mass="14668" checksum="049CC95F3AAC037D" modified="2024-05-29" version="1">MTENSQQIKRKDSRQLLNALNVKSQYPIIKLSPTTGDVFAEKTLDLIEPVKIGRKLPPKCLPSPTNGLFDSKVLSRNHAEIFFQDGKVFIQDKGSSNGTFINSKRLSDEGIESSPFQIMSNDVLEFVLNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYH9</accession>
    <name>A0AAD5TYH9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MORN repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000525">
        <property type="protein sequence ID" value="KAJ3215720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052849">
        <property type="entry name" value="MORN_repeat_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46917">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46917:SF1">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="28907" checksum="60D519CE2E5070D6" modified="2024-05-29" version="1">MSEKSRHSLSKIKKSDKSLNNSKHPSTVELKEPPVLQFGKFIFSDGTRYEGNYQQIEITNSNVNQLISNFNLNDENLNKISIEQKELVQQPKVEQATQNLQEKLTQPANNSNVKDNAGNLPKTGKSNTGNAPNTESSNAVTENLNDDEILNVESKTTIVRHGFGKNICGRTMVIYEGEWNMDKMDGKGILTFPNGVEYNGNFKENKFQGNGEYRFSTGSKYQGTFDSGLPHGNGCYIDDHKWIGTFFKGKAVGIVELTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYP9</accession>
    <name>A0AAD5TYP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001305">
        <property type="protein sequence ID" value="KAJ3204396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYP9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="117" mass="13419" checksum="5CA874A337CBEBA7" modified="2024-05-29" version="1">MSKLRVGQAVINVDGVISFDSIPRPNFGRLGRKITVIANLYKFPFLIGIFPDMVYHYVAKCVNNVVVKHDKVLKPACRKIMEAWKNMDHSATLDWASKDRENAQYSKQLFDLKSLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZE8</accession>
    <name>A0AAD5TZE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000397">
        <property type="protein sequence ID" value="KAJ3218068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZE8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008626">
        <property type="entry name" value="Mediator_Med15_fun"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05397">
        <property type="entry name" value="Med15_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="629" mass="71544" checksum="22DBAC4B46EA28AC" modified="2024-05-29" version="1">MGKKKKRNFNSNSLVHNNSAFISPSDQLKNIELRNTTNELKGKLHLLINLVTVLKENNFSYDISIQPYKHGKPPSEIKKHEDGSHYSDQRLNDIVHKMHTTYNSIDVNKLSDRDVVSTRNFNPVTVRMTPANLTEVEQAFVITKINEIAGSYSKIEGWIEILECCNRIRETDMALKLRGLKRMLEVQIDGLKQKPKIFFLNPETVLSLLQNLMKFYQYANNLKKLYDHSITLLEMQHKNKRLEKDNSSTSKMMSITGAVNGNEATGYNGGEDEKTCKVVNGNESTGNKGREGEKNFKAISCSEGAGREESEDGKSFKAVSVFGKDTVIGESISGSTPQTFLQQKTASGVTLKITPADLNDDEKFFVVQKLKDLAPLYKKMDIYIEILSKFRNDTDFEVLRKFKGMKRMVEVGLEGLEKGGIFYLTPHTITHLKENIQRVFKYIDFQVMKRNKDRQEIKKAKHKQAAPPSLSSSSPLLPSQTEPINAEEEQCLQQEDIPISTPVNRSSDLESYFIPELNFKLVPLILNAKDQELVNSKISELKRSFESVKLEMCVEFLETHIRKTGKVEGNEADLLKKIIGMKKLWTLGIKGFNKESKIYYFNPNMADSLMEFLVLAFKHIGEMKNAGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U050</accession>
    <name>A0AAD5U050_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000352">
        <property type="protein sequence ID" value="KAJ3219107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U050"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="104" mass="12205" checksum="A95A2AA7F485325F" modified="2024-05-29" version="1">MEVNIEIDKDLGYTKAIHIMFGGELAKKFNDIIYKDNAYMFFHHSSDDSYALITVIDQETLWKILFCMILRDFLKIMGPPKIYAYWNGKEIITVENTIVENTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U110</accession>
    <name>A0AAD5U110_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005837</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000474">
        <property type="protein sequence ID" value="KAJ3216523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U110"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902977">
        <property type="term" value="P:mitotic DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003874">
        <property type="entry name" value="CDC45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507">
        <property type="entry name" value="CDC45-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507:SF0">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 45 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02724">
        <property type="entry name" value="CDC45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="361" mass="40416" checksum="11BBFE4D7A6B7B0E" modified="2024-05-29" version="1">MSEIVFPSFVRRFGYKITTSASDGVYSSLLDCGGDWIDRYAYGDIPMDIAMNRVNLNSASSRLGVLKGGVKRHDESVDGRGYGQQQGRVAFNINILRILSFLYIKGVGVGTKTGLAAIGLRLIEFSEGLSKYQKSSLKSGEESEEVDEDEKWVKNFWVAFDSLENSDLMVYGIHLSMQFQATLVETGVSILERSIVRSFKKFRLGVLNNGTGISITSNNNQENRSLLNFLNEKEGNQNQKNNSGKPQSKRVKTSIDKEFSIFSKSSTHLKKLSKFILEAFQACNYTSLPLILAFLNEENDTFLCCGTMLLSKKKKSKFGIAFQESAELSGAKVKHDSFDVCVIEIKREDLMDFIEKLKLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1C6</accession>
    <name>A0AAD5U1C6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidate phosphatase APP1 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000267">
        <property type="protein sequence ID" value="KAJ3220868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1C6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208:SF3">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="APP1_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidate phosphatase APP1 catalytic" evidence="1">
        <location>
            <begin position="189"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="467" mass="53388" checksum="8296198214A32B78" modified="2024-05-29" version="1">MSERNRQMLNLINDDVTVSFSPTYASYDKLARIWNINLMGWVFKTQGSLSTKLQHTIVSSIGSISLRNSSKETSDLFRERAELLALKSTVKNFKFEIRLCGVAEAPSIDSKLYECNFSYPETKIDLETNNSGYFQGKIKLKEEVLKDCLIKHNLDIKNDLEDKNFYFLLKCSANKELFNFVQIISPIGISVISDIDDTIKESDVHLGKRALIANAFTSPLKAAPGMSDSYRYLQQKGYKFHYVSAAPYNTVDITLAFLETNSFPFGSLNLRNVYLGGKNTVVYKNDIITKILNDFPDRKFILIGDSGEHDMMIFKNIFQLFPTKILKILIRDVPSAILEGDNIFSQRSVTKKLCESRANLIFQGLENTIWNLFHDSDFVLTESLKFLNFKEKIINFVEEHSGVRKDEGVDNSKLPEQNFNSFINDEGVENSKLLEQNFNSFMNDERVKDIFEENSNNIAVIQPVLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1I2</accession>
    <name>A0AAD5U1I2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF659 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000686">
        <property type="protein sequence ID" value="KAJ3213688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1I2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="442" mass="51273" checksum="A7D1CEB874E1E177" modified="2024-05-29" version="1" fragment="single">MSKFNTLPSEQEFDYGELILVNLSQNKSLDYRWSGFKRSVNKKNNRNLAQCSYCLEKLEGRVHNFPKHVSLCPAISAQNRELYFANLNQFQKKGELERDVLQNVSPVVVDKEAAVQKRPKLQKSFRSISDNESKKLHLGFAKFVIVSGNVGFRLMENPFFMDYQKVLSEGRHFELPDRFNLFNSAIPELYKGMVCEKNLEVKMQDSLTVVLDGWADFDEHTRYAVILRKGAENFKYYIGNINMRKNLRLAPNILTGIEDIFKEKNFNFQSCLAVVSDNSNVMMSFKKLIQERYPHITPLRSVLHDFNAILRHLIEKCTNTRVNTILKNNKTLINYLHQLDIENFPGKNKKKEPFLEIDSESTVDSRWKEIVKNHVSNASTTSDSNSSNNNILEVLKDDPYHFLENQIILNIISPLKETISNLENENSNIGDIWPQFIIAYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1N1</accession>
    <name>A0AAD5U1N1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Guanine nucleotide exchange factor lte1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LTE1</name>
        <name evidence="6" type="ORF">HK099_003580</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000235">
        <property type="protein sequence ID" value="KAJ3221354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1N1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF363">
        <property type="entry name" value="PROTEIN SON OF SEVENLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="149"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="595"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="930" mass="106361" checksum="341D7708A5AA0B73" modified="2024-05-29" version="1">MLGNYYQDTKLIKSDQDSNRCYSLLLPSLDKIASNNVKPFSKKSIRSKPSEITASTAEDKIDKNTRPNENALKTASSKTSRYINRDSIKSYFTCTDELSKIEGKLVIDLDEQFTEFSKIDVILKEKNIDIDGKGKILLLDEYQNKVLKSEVEFLAGTVDKLSNWLISTEDSSFIEDFLLTFRYFLSPSVLGEILVSNLNLKENSATLYCTKDSIFEHYLEEDSKAEGTKNNECSNNCSNGNGVTPNSVDLMLLRDMEKKKLAGFRKRTLKLLGRWSLSWSEDIMNFPSLFQLLKNSLTSLQKELEFTSENTVKEDNLIKAILNNLKYEEPKLLNQQKSLLKFEEVEADLLDFYSTFSRKEVAPKKNTTFYNMHGFDSQVTCKSVTSSGPSNFSASSSLNVSFDFSNNAKGVILPNLNEKDTQIHDPSLSKVYVKDIHPETKVNETLKCSSGKYSSSAQIKKMKKSLFSNLLKTRDTSAGSNEDIIKVEEEKLKRENKRQFYRSSVVNHPVVKSTISQKELENGKKVREELQNPQPVPAKNLLAVVTKPPPPKVNTKPLSGEPTKHSKDELQILKSITTTSDNFENLRKSLVLNYPPSLIAKKLYLLELKTFNKLKLQDFLKVESWSHQNFIINFEGEGKRSCINFWREYLEKVYISDDEFVKVNFERSEGNFCSSTSYFENKTNLIENSANSVSCLIKRFETTFQWVLSEILLTKDLATRIDILDAFILLARSCKELGNYQTLILILLALQHPSVRSLTSTWSGLSDKGWSTIESLEKYALDCSLENKSWKIFDDTEEFLFSKKSKRENKVIIPFIGIYLMNLSIIWKILPSQIRANHFLKKSNSSLKELDQLIYFKKFRLISSNLKKVKKSVDAVNELLKGEDHKEFRSRVLGGVEGDCDSLDVYLSNYGGIKLKNEREWDFISSKLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Q5</accession>
    <name>A0AAD5U1Q5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Neutral ceramidase</fullName>
            <ecNumber evidence="5">3.5.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003539</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an N-acylsphing-4-enine + H2O = sphing-4-enine + a fatty acid</text>
            <dbReference type="Rhea" id="RHEA:20856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:57756"/>
            <dbReference type="EC" id="3.5.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the neutral ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.23" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000231">
        <property type="protein sequence ID" value="KAJ3221417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Q5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017040">
        <property type="term" value="F:N-acylsphingosine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042759">
        <property type="term" value="P:long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2300">
        <property type="entry name" value="Neutral/alkaline non-lysosomal ceramidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006823">
        <property type="entry name" value="Ceramidase_alk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038445">
        <property type="entry name" value="NCDase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031331">
        <property type="entry name" value="NEUT/ALK_ceramidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031329">
        <property type="entry name" value="NEUT/ALK_ceramidase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670">
        <property type="entry name" value="CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12670:SF1">
        <property type="entry name" value="NEUTRAL CERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04734">
        <property type="entry name" value="Ceramidase_alk"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17048">
        <property type="entry name" value="Ceramidse_alk_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042133672" description="Neutral ceramidase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase N-terminal" evidence="7">
        <location>
            <begin position="29"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase N-terminal" evidence="7">
        <location>
            <begin position="366"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Neutral/alkaline non-lysosomal ceramidase C-terminal" evidence="8">
        <location>
            <begin position="543"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3221417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="703" mass="77001" checksum="5D0610983264276C" modified="2024-05-29" version="1">MHFTEFILTVFSLISINLGFPQSNESTAFRVGVGKSDITGPIGEINMMGYAMLDNTANGVHLRLQSRAFILASPLNPNQRIVYVSTDTGQVSHSSRNDVARILKETLNSNIYSVDNIMISATHTHSGPGGYLDELLYHITSSGVVKGERSAITNGIVDSILKAHKDFEASGSSILTLHEGINYLKNFLFSILGELLQTSVNRSPSSYELNPPTEKQFYGSNTDKLMSLIKIHDNVSKKLKGSVNWFSVHGTSMNNKNAYVSGDNKGYASYMLEEIERQKDNLNFVGAFAQTNSGDVSPNTDGAKCSDTGVSCDGSWGDCGGDITKCFARGPGFKEGGDFLSAKIIGGNQFKKALELQNQGALLVLDRTEVKTCKPAMGHSFAAGTTDGPGTSLASQGANSTAHLSKLLDFAKDLIKNPSAEQEKCQAPKQILLDTGEITWPYAWQPTILPLQLFVIGRKLAIIGFPSEITTMAGRRLKKEIFDTLRTTDRIDPDARIILSALTNAYASYVTTFEEYQAQRYEASSTIFGPHTLNAYIDQYKAIALSISNSQTKPSGATQPPVKIENPLQLLPDVVLDTVPIFKNFGDVQTQPVSDIKVLSTVTAVFHCSHPRTQDIYKSFFTIEKFVGGSEQWITFLDDSGWDTKMLWKRVGVSESLCQVDWSVGETRAVPNGIYRIHYYGKRSTFGALNNYEGITKAFTVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Z4</accession>
    <name>A0AAD5U1Z4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005759</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000464">
        <property type="protein sequence ID" value="KAJ3216711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Z4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="299"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00068719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="387" mass="44146" checksum="24A4F676228EE991" modified="2024-05-29" version="1">MGIVGMPNIGKSFFFNALTNSNVPSENYPFCTIEPWEARAKVQDSRIDKLVEIYRPKEMLSAFLTVIDIAGLVKGASAGAGLGNNFLANIKSVDGIFHLVRAFESTTIEHVEGTVDPLRDMEIIHLELRLKDTEIIEKLLESKKKETKRLFSSSKMSAQDKLKMKELEWLKKILHHLTEKNLCVRQNVEVWSEEEVTYINSLHLLTAKPCIFLINMSTEEYLKKNNVYFKNIQNWVNTNYPGDQCIPYSGIFEAELSVFDEQEEKDMYMEEVAKEFKVKTESATSTLNEIVLAGYNALNLIYYFTCGPQQVRCWTVQKNTKAPQAAAVIHTDFEKSFILAEVIKYGDLIQEGCEENVKTAGKILQKGKDYLVQDGDIIHFKIAQKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2B1</accession>
    <name>A0AAD5U2B1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inositol polyphosphate-related phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000212">
        <property type="protein sequence ID" value="KAJ3221734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2B1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="525"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="558" mass="63767" checksum="57133144DDC1B6A8" modified="2024-05-29" version="1">MENILIQILSWNVNTKAASKSKLKELKLLNLINTPNFENQSNPPDLIAVGFQELLDHFIALTYSPEESYFGTNNILNQFKKNQLNILLSWVEEINVELAALHSNVRYAPLFASRVVAIGLCIFVRMDSGGSNGYISEDPIIQGEYDDIVDANAESKFGILNCKFGYKKNLTIRSANGVGLGGFYGNKGAVAFSFDLQLAAKKDHADPQVISICFLNAHLQAHEGHHYFLCRNEDLKQIFDCLVLSPVLGSLSRSTLLFYRNPIGFLKNFIYPYHIDNEIDNEEGIKNLYSHNVIFLFGDLNYRLKKNFNFTREELLSNLKENNVEKIFEFDELQFLLKNVNRGVSEVIVDSISQGEFNFPSCYNGFEEHKVTFPPTYKFSIKNDKKKNNAVGDETTGNNVEYSKKRFPAFTDRILFKKTLGSAVNTNNWINSKVLCHYYNSVTKMHGFSDHQPISGLFEIQGSFKDAINKDGSKQNQLTDCNRLKRIDRVEKAVVASLKVKSSKLYDESLLVDMKLVKKLRWERILKLAVIPSLYLIGSFSFFMCLSYYLYLNKTKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2J8</accession>
    <name>A0AAD5U2J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000186">
        <property type="protein sequence ID" value="KAJ3222206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2J8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053181">
        <property type="entry name" value="EcdB-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47785">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="666" mass="77458" checksum="9A75FB990DF4A216" modified="2024-05-29" version="1">MGNLRGMVSKQACDMCRLRKRKCDSVKPFCSKCVMLGQDCVYREICKKRGVKNTLDKSIEKIKVSLTTLRESFSENGENKSESKLKKKDKLPQEKNLNTVYENNPNLVNDNSNDSNFTKNGSLQRINKFSAQTETPSVLKSNVDFSFYSNPDNFSNLKKFFDDLNQMFLNNGDGVFNLSNYHVLLKTLSNQNLLLAYGSDSLRTYLPNSIQDFPYFKIGVDEKLKHFIRNNIPVVPNDCVVVSAIELEEGSDHNAAEDLNLKNENLLYLHLNRTVYQKNHFYLAAIKSYSANKRNLFNKYYLSSKKVFCEVEFAKLMISNLNDYSLYLSFALGCLRSRHYLLFTEKFGGSPYKASMLFAKMTSDILKTVVNSDEIYSIGYIEIKLQDIGYLFNFDKPNPENKFQKLYNDIEDIQARKIIWARVVRFTKKNGHFHLQDFSVFNAIDILDLHNKLIEWHDIIFPEKFRIFESLMDFWSIRGVKSLEHLNWNLRLCNMQLNIWYLWALIKIHSSQLNETRKFKLSPLSEIEGSSLDIILCSIRALSSILLLKLPEKKFKNFESVQNRELLGFCNLDKEFLPIVLSPTFEILLGESFKDIIEICLEKLKCKAGWSQNEDLQWELLSFHFKGVLLKILETRENPFCIRITKSLRTQIGVALDILEIKNLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2M9</accession>
    <name>A0AAD5U2M9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000193">
        <property type="protein sequence ID" value="KAJ3222082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2M9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="159" mass="18475" checksum="4D39E86CFD279FBF" modified="2024-05-29" version="1">MTGGTAFVVTASILLTVMLYLNFIPHEIVLSQLDLMVIPLSGKIYVFGLAMCNFVLCWLGEVFLFPKISDFIGYLDLVRVCYNLRKSEAYKKDFLDEEVALVPNNNNFSNEGIQIENKNKEKEFFRNEAKILHWKSKNKIFKIVDFRFKEEIQNLIALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U381</accession>
    <name>A0AAD5U381_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_001742</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000152">
        <property type="protein sequence ID" value="KAJ3222936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000551">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="11">
        <location>
            <begin position="211"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="275"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1346" mass="156798" checksum="426D74816E583179" modified="2024-05-29" version="1">MKILKKGDVVRLKQVEHVNNERNILISIKFPFIIKLFQTFQDKVSLYMLQEYGIGGEVFSYLRKNERFDDYTTKFYIAEVILAIEYLHSQDIIYRDLKPENLLLDSIGHIKIVDFGFARKIENNICYTFCGTNEYLARNILLWQSFNSFLLQLRLLEERDMGNPLIGGHSEFSLTSFLLDSLHFMAHHLWRYMLGNLKNGVIDIKSHRWFQGIDFNELLCKNSNLRVPFKPTFKSFSDTGNFDAYEEINLKKSSKDKKLEFQNFDELFKVSAMSTDEYHPISYFVFTKANFKDNEVLTGSLMKSTLFGKVVVLNPIFKKYAQLRCEINHCRIAKAFGILTDLSTLALVMDYYSKSLFDRICDRTLPQLSSQERLQITCEIVEGMCFLHENNIFHYRLQTENILLDSNLKVKINNFFTPILYNHHETPWRYLKSIYEYRFWLAPEVTIMDVFDFSSDVYSFAVLLTELYTSIGPWGIDLSNLPPSSFYEHCHNLNKGWRLDISSMDNIPLFLQHIMSESWDSHYFSRPSFREILVRLDNSKHRIFINSTNSIKNSFSFRKLDRKYSAHSLRSEDSVASIDNYGLKNSTSYEMLYKNLSSSPYFMKSTKDGIPHKIGKQMKVLKNNIFLSKTRMKSYEEMDIENLTDKMKNFDLNLGISSTTKNLKITTTDEESFKSSKCFEIIKEMCFLEGKMTKLIKTFSLLKPQINDIITKNLSNNNFYEIPKQVQNFNLEELEKSNKIKLFLNCNIFFEGFEEISDCCENIFFKILKIINIPVNDDYSFKTTKSERGLVDLASIRDLIKVFQDEMPKFQSYLNFIKNYSSKLDAKNKMNELPALTNLLQKHRTLIGRIDFDMFLNLPVKHFTDYALHFNAISKCISIEHPIKSDVINISTFMKTLGVSMDNIIGLQKKSNRFSTLTKVVKDCPQLSKSYNRYLLEEFFIPKFEDTEKEGVLFLFNDLIMFTERNKTENEAKVKGNVGFNYYYPQAEFDLNGYSYKCHFQLKDVIVRNYTKNLGDIQIILIHAGRKENSINLSMSTTTAEMFIKSFTKAKFNCNKYLFPSITHSIDNLEEEKVYLVHNNFDATNNLELDLITGQNCKILTKFADGWGEGETQSGKGFFPLACLCEPFTFNHNFENFKFPLAVYKVENSPNPLNSNPLHLNILEGDYVSIQYFSFTDDLLIYGKILGTRINDEQKDVQLVSRIGKEGWFPVYSTITGAFSVVESVIVEVDIQHPSRNVETIFKESSFFHKQSANDDLMKSDLAFEKLCEDSQDVEENALGNRATLKLTLEDILDVDIINDLEEVMGKVRGVRLVKYKNRFIKVVNPIATLKLKDLKPFILNYELNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3B5</accession>
    <name>A0AAD5U3B5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000241">
        <property type="protein sequence ID" value="KAJ3221253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3B5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="367" mass="40838" checksum="E124CE4C9014A6B3" modified="2024-05-29" version="1">MDGMEKSKCSYILSESPNIADIQGSHGEPAIKTILSKKSKPYICQEILETNLDLKKTHSGVLNEGEPDPILTKINLKFSQKDSNISLDLLNDQELEAWNARRGFLLKNSKQYKKEKVKIANKLHNEELQESLESTTSSMCKLGSMKSNLVFLESLKGDILDLSNLELTENSSPEQSSLLRLNSSLKPSTLSHSLDQKDCKKNYKHSRLNNLIEYEPKVPRIRRVSFSDSILGSTNDVAAEFCMQKSNTGGAFKVKSDHNNSIQFNSHSRSLGSNLKMTALITPCSFESIAVRENTRIAPVEGSLETLEEKRTSVENKAVEARVSASSDASKVVVKNSIGKFISKIFKKKRSNLDFSSDSLDKLQVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3H6</accession>
    <name>A0AAD5U3H6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000139">
        <property type="protein sequence ID" value="KAJ3223214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3H6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="409" mass="45838" checksum="3B04043DE46874AD" modified="2024-05-29" version="1" fragment="single">GYTASPKKFTLITKNIIRPFFQWKNNLGYSAEVTLLQSLMNFGGWTSQSNVRSIASPYNQLTDVNNPLNQLVFEGTNDNSLNNFGNAAKFLGLQGETFDSSSQKGGIDGYKDFMTWVKKEVIKGNQVALGIIIDNGPYDHIVPVIQIESDYSSDNLTWHDDDMLYIDDHGEFAGACNGTNSTTSCFWMKNTDIPYGSENTVGCTPFFYGHSFANLTLNATDYRQFQIFIPNEGLTSENKNFAFSISGVIDPYNVTFPVKLQIADNGSPYHPIAGYNYESPMIAEAANETDIRNILPAPTKLKFLITVTGLTPGNSYNLFRFEYTGRPLLGQLDIPSFNFNANKDKASQVLTFTAKNQEFFLSYEAMSDHTIIYRCVSVDEKLIQLTSNSVKNSFRFIVLMRLFTILFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Q8</accession>
    <name>A0AAD5U3Q8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein required for normal CLN1 and CLN2 G1 cyclin expression</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CTR9</name>
        <name evidence="5" type="ORF">HK099_001102</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000129">
        <property type="protein sequence ID" value="KAJ3223457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Q8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031101">
        <property type="entry name" value="Ctr9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027:SF2">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="19"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="169"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="580"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="580"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="661" mass="76224" checksum="4D27B56F6CE86C77" modified="2024-05-29" version="1" fragment="single">ASIFATYAVNNHKFKKIQAEALSIKGKIHHINNEYDEALKCLESSLALNPASLAVHFGLGQLYTYQGDFDKAIESFQFILQKEPNNYETLKNLAFLNSKKASTKGAALEDFKKLNLIMKTFEKSDKVGGDPEVLVEYGRLKEETDIKEALEAYLQAKAILENSEDGCSAELYNNIGALYHIEGNIEEAKKYYTLCLNKTTSGDHTNTSVLYNLGRLHEDKAETKEAEDLYKLIQTKHPAYVDAQLRLGVMIMEKGNMNSAEDFFRDVHVMDSKNIESFLLLGKCQQLGKQYKLARSSFVKVLQEIDSHDLYALCSVGNLNLKFARTDPLQKDLHYKRAFEFFDKCLKIDSQNYCAALGVAICLAENSRFTEAKEIFSTLRGVTLDIPAATVNLGHIFIELGQARDAVNLYEHASKKYYENKDSYVLHCISRAYYIIAKSERDEESMKKSLRYIQLAARINPSDLSLFYDIALIKQQYAHVLNDQTIDKRPLLKLLKAAEGLETSRKLFAGLSEIPPSSYLGYDVNHARERGNYCKDVKRATDKKIHETEVLERMNKERMEALIEEQKKLEEQKKKIEELKREEEERKQNEIEMKRRELKQKMQEEHERMSMYEREMEKEEREKKPKKKEKRLGGSDEDSDNATDRKKRKLSKKIIDDEDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U442</accession>
    <name>A0AAD5U442_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tail specific protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000115">
        <property type="protein sequence ID" value="KAJ3223841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U442"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060:SF22">
        <property type="entry name" value="CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060">
        <property type="entry name" value="TAIL-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041988246" description="Tail specific protease domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Tail specific protease" evidence="2">
        <location>
            <begin position="281"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="814" mass="90490" checksum="8CB325392D665853" modified="2024-05-29" version="1">MLFNFVKAAGILALASNLQSQVTEFEYAPLTSYLKEAVFPEYSTDQKLFLADQIHKLFTIYGNRDSKVQHYNVDSDILFTDIKNRAANLTGAELNFQIGKAYKQLRDFHTAFKFPAPYACYRTYFPLSFTLIDGADALNPVAAVSGFNTAAKSVWGNELAEVKLGHILVSINGLSLLELYEKYKHLSGGANFYGGMKSILQRLFMVRGGDLGTELQLDENETHVTYELKQRHDSKNTYKVTVPLAGRKKNSCLAPAAPVSHIATDSKKKTPEPFYNDFNEVINESYEIPSDIPYEIIPGTENIIGFAHYKYLGTKLGIIRISSFYPTNYGLIEHLVLTIRGLLVKEFKETDAVVIDVRSNGGGWGLFSNMIPQLFKADFVPGFGSTRKSPINDRIFQNPGHAGFEAYGATPEGQPYSNLFLYETVAETNTFGQAYLKPVAVLNNANCYSSCDIFSAAMQDSQTAKVMFGEDGATGAGGCNVVHHENFRQYNPVDFNAPLPFGVDVTIGWQQLIRNGVNDKKKVEDFGIESDVILRPTTFDLFNVNNRSSVFDRIAHQLRAIGQADGSFWTYFNGEPQLNGDSEVGAPVKFSVTVGYITKLELHLKDKIIDSKTFNLRKHTENSELTGSVANTVGIDHYTIYGYTNDKQVLKTERYIRYIPASSSFLQILPNQTTKWDFKTDTYAALYNGPQTTNDKGFNVQDGKLVVGDGKGYSDSIDTSVSFFVNLNGGLPKIQLDLEFSTETDFDFVYLTLKQKNRKDIEIFKSSGKSQHVNQTFRNLGAVDGPAEIVVRFVSDGGVTDVGGIRLNSISFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4L2</accession>
    <name>A0AAD5U4L2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000165">
        <property type="protein sequence ID" value="KAJ3222645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4L2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="374" mass="42965" checksum="519BAEBABDB7DBBF" modified="2024-05-29" version="1">MGLSVLNCIGITNSLYSQRTTQQSLTAQQQQNIPASTSQHLKRSDSKFDANFTTSNPPLNATSFALKKEKTNVNLLKAEKQIIENIKSRIIINNKALKNREFWSVTGSSLFKNIFSVSKYLTKYPLEVLQRRQQILLNLKYDPKKFLYLNLYKGLFHNVCWKISFEVVNFFLIKVSKSLYYVEKEESGKEYDGMVVDKKDLLNSNYFISLLSRSASFLVTFPIYKNSLLLGLNSSALSNSPTSKSGFALLLALYILKDDFENLVLKNLFGLNFLKFILKAIEPLKSQLKKSHLQKSQFNINITTDDIKKNNVKFKNSLHLKFKSIYVYLLLDTLGLAISEVVFYPVTTYKTLDVAFSKYLNKVSNHLNNDYLFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4V1</accession>
    <name>A0AAD5U4V1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000092">
        <property type="protein sequence ID" value="KAJ3224465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4V1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="36"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="500" mass="53820" checksum="83CF771E7B9F5B86" modified="2024-05-29" version="1">MATTTTLKSDEVVDISDSTTLVPVSNIPKGIKFKLIFVSLILAVFLSALDQTIIATALPAIGNEFKEFELIAWLASGYLITAAAFSSLYGKMTDIFGRKAMFLVAIFLFEVGSLICGIAPSMMVLILGRVVAGIGGGGIFTIVLVIIADIVPYEDRGKYQGLIGAAFGVSSVLGPLIGGFFSDSALLTWRWIDFVGVFLLLICIVSFAVPIQAGGSTWAWGDWYTILLFVVSAFFGVLFVIWEINYAIEPVIPAQLFSNFSVKALVAVPFFLGASFFSFAYYVSVYFQIVKGESATMSGLDTIPLIAGLVIFSIFSGQMVSRFGRYWVFLFVGAIVLIVGNVLIATIQVDTSKAVQSIYLFVIGVGVGSQIQVKLLALQATVKPNMVAIGTSVSVFAQTVGGLIGIAITGTIYTNNLAHNLSRSNVPKELAALIISNPAALRSVIPLELQPVVLEGVCEALRTAFRYIIPFSVLLFISNLFVKEYEKGEVRRAKQKEGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4W5</accession>
    <name>A0AAD5U4W5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exocyst complex component Sec3 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000094">
        <property type="protein sequence ID" value="KAJ3224395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4W5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019160">
        <property type="entry name" value="Sec3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092:SF14">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16092">
        <property type="entry name" value="SEC3/SYNTAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09763">
        <property type="entry name" value="Sec3_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exocyst complex component Sec3 coiled-coil" evidence="1">
        <location>
            <begin position="21"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="244" mass="28161" checksum="84B51646683FC981" modified="2024-05-29" version="1">MSVIDKVLKDFNWEIGGDSSHLEAKLREELGALEAANIHSIIQSEDQANEVIAQIDTAVDQLTLIDEWLNHYTNVLDSMGADVHQVEVRNKNLQTASNNQKILLQELDKLVSSLKLPSYIIEILKNEPLDFTDGILQCEEATIKLNEAIKKKFDNENMNAVKERINLFQGYGNEFALRLCDYLSNLFSSQIETYLNDEQRVSKKGSLKLYGIESFEEKLYRFRKLLAWLKDFDPRKHQDLQMVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U596</accession>
    <name>A0AAD5U596_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000296">
        <property type="protein sequence ID" value="KAJ3220508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U596"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF169">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="68250" checksum="697E7FAD194E2AFB" modified="2024-05-29" version="1">MLSYNLLTSCKQFRIRILQIPKEIIILVAQYLNADDFLNFALAAHHLYIPLYLSTDKNLVKIAAKKDNPSFCVKFLSVNKNICLEPSLREIVVWAASGGYVVLLKELMNTFVYNPILEKSAALKSASQFGHASIVDWLLQEIDIQSVLAESFCLACKNGHIQIVRRFLGEPKVLILDNIKHLLVVAAEKGHLTIIKLLLQNLQDLDWGSTYGFALWFSVLNGHHFVLKKLLELPSAHLFGNSLIKVAVENYCTESIKVLMQDDRLELPQNQLEDLVKFSLKNNYTVGVDLLLQRNHLTSAKLKELFLLNMEDGEFGSLERILKEPGFCAMLDGSKILISAARYGKEEIVKKLLAIKEIDASLHDNLAINRACLYKNIVVVMLLLEDERVKRRLDFSVLANLASEIGSLPILELILNYQNAKFSSGIYHPLIQAVVNGHSEIVKRLLLDIRFDPSELNNLAVIEASKRGFYDILTYLIHDKRVDPSAQKNIVFIESCRRGYGPVVDILLKDNRVDPSDQDNLALIEASSEGNYNIVEKLLKDKRVDINAQNNLALYKARMLKKNSFNDILELKNLPTSMCKCKNSARIINLFLDLSDTDGSDCEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5A8</accession>
    <name>A0AAD5U5A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="primary">POL3_3</name>
        <name evidence="26" type="ORF">HK099_007774</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="JADGJW010000079">
        <property type="protein sequence ID" value="KAJ3224837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5A8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="17 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 20 26" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 20" id="KW-0408">Iron</keyword>
    <keyword evidence="16 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="25">
        <location>
            <begin position="96"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="23">
        <location>
            <begin position="195"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="22">
        <location>
            <begin position="494"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="24">
        <location>
            <begin position="955"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAJ3224837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1047" mass="118265" checksum="BC0F847C93B4D00B" modified="2024-05-29" version="1">MSQLSQYSSDTLKRSQDSNEDFGSQKKIRKSAFEDVLTNMMDENDENAVFQQLEIDDYEDSPYFNVSNPHNSTVLPCLRMFGVTDTGNSVLCHVHGFQPYFYAPAPYNWNPNNHTESFRRVLDMAVRNDSKRNSIGGVAITHIRTVQKKSIYGYRSTNSTFLKIFCRIPSQIAAAKRLLEKGIHLEDGGSFSTSVTFESNIQYTLRFMIDRKIVGANWIELPAGSYTVRDRNITSSCQLEVDVIHDKIVSHDCEGEWSRIAPLRILSFDIECAGRKGIFPDANIDPVIQIANMVTIQGQSKPFIRNVFTLNKCANIAGIHTLCFDDERDLLKKWHEFVSQVDPDLVIGYNTTNFDLPYILERTTVLKVSGCPTLGRIIANKTVAKETKFSSKAYGTRESKEINLDGRLQLDMLQVMQRDHKLRSYTLNSVCAHFLDEQKEDVHHSVITDLQNGNEETRRRLAIYCIKDAYLPQRLMDKLMCLINYIEMARVTGIPFNYLLARGQQIKVVSQLYRKTSTMDLIIPAMKVEGASDEVQYEGATVIEPEKGFYEKPIATLDFASLYPSIMMAHNLCYSTYLESKKKVEEAGLVLERDCVITPNNGVLVTILEDLISARKKAKFDLKLETDPFKKAVLDGRQLALKISANSVYGFTGATIGKLPLLAISSSVTAYGREMIEKTKELVEEKFTIANGYEHDAKVIYGDTDSVMVKFGCSDLAEAMRLGKEGAQHVSTFFVSPISLEFEKVYFPYLLINKKRYAGLYWTKPDKYDKLDAKGIETVRRDSCRLVSYVIQTCLNKLLIERDTKGAEDFVKNTITDLLKNKIDLSQLVISKALGRSDYVGKQAHDVLAKRMKERDAGSAPSIGDRVSYVIVKGTKGSAAYEKAEDPIFVLENNLPIDTKYYLENQLSKPLLRIFEPILGDKSSSLLSGDHTRTVQIAAPSSGGLMKFAVRNATCLGCRVPLGKIDTAVCKNCKPRILEIYSNHLTSANVCEVKFSRLWTQCQRCQGSLHQDVICTSQDCPIFYMRKKAQKEVNEVTATLKRFDYSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5G4</accession>
    <name>A0AAD5U5G4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000276">
        <property type="protein sequence ID" value="KAJ3220743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5G4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="283" mass="33080" checksum="40A6F42332DBA21A" modified="2024-05-29" version="1">MSITQIEKLFNIQNIEIKKLFKQQEDNVTSLFKEQEDNITSLRKDILRLDKDIRRLDLNSGFNREFLLRQAVSRLFGDSFAKSFQVRCLDNIIHLIAKSGVFRREDDISYLRLDKTNLLAHSLLDADIPRQLFNHCLECIKHRNGDVYKKYEDITSTEPQIIGRLLARIYELIEMYKSLITKPSIDARLKYLRSKKGPGISLVIFAANEKFFYDNPNRLPERYLDFDVRGNIEIVDDSARISVGEVKTAPEEFGHAKSQLKIRLQVLKWAIEKVVPNVKQFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5H0</accession>
    <name>A0AAD5U5H0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007338</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000070">
        <property type="protein sequence ID" value="KAJ3225133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5H0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2040">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043451">
        <property type="entry name" value="Myocardin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004018">
        <property type="entry name" value="RPEL_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793:SF12">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22793">
        <property type="entry name" value="MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00707">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51073">
        <property type="entry name" value="RPEL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="4"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="RPEL" evidence="4">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="199" mass="22559" checksum="E4B3326AFD1D8987" modified="2024-05-29" version="1">MEKNLLKEKLEKRPSKTELIELNILNNLNVAPSLQQVTTSLQKSIVQDTLKHAINDRPGQEHLLNQNILHYANISPAIQSASDSLEKEKKNDSLRKSILERPNKSELIDQNILQRTNVAPSLQSTKNSLEKCILQDSMKKLTNERPEKEDLINQNILLNTNIAPALQKTAIELEKSLKNDSISKCLLKRQNAVVTNEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5L5</accession>
    <name>A0AAD5U5L5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">H(+)-transporting V0 sector ATPase subunit c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">VMA16</name>
        <name evidence="13" type="ORF">HK099_007083</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000066">
        <property type="protein sequence ID" value="KAJ3225257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5L5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18177">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18178">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000002">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="104"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="194"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3225257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="28103" checksum="F9A2D358A74FE946" modified="2024-05-29" version="1">MRKRVSQRTSQFNIETNHEINIDLIDSSPTSARFNNSFNQPLTLVLENKYLSMDYFYSKQSIYGYLLFSSATVVTLYLLFTGQGEQFNIGDFLLRTSPYMWALIGCALCVALSVVGAAWGIFVTGSSLVGAAVRAPRIRTKNLISVIFCEVVAIYGLIIAIVFSTKMNGEAFAFESSGLPYTRQAYYGGFALFWGGLTVGLANLFCGICVGIIGSSCALADASDPTLFVKVLVIEIFGSIIGLFGLITGLLIVGKVADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5U6</accession>
    <name>A0AAD5U5U6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000103">
        <property type="protein sequence ID" value="KAJ3224140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5U6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="359" mass="40887" checksum="59E5C28DD42B4F84" modified="2024-05-29" version="1">MTALKKKRNYFSKETTEAPIEDFTPVDRKVSTVDIVIVIVIVAVVLLIFAIVFYHCTRLSSRLNSNVRSFSDDSFYSETGDSLGWNSEPNLNLNLQNDEKMFEQVEFQIEEHLKKNSNPTNTKKKKRNRKSVNTTSSNASKTSITKKIKNYSKNRNSLNMFQIQQEKLNIPSNFVAKSNTSESYSQFYNLNNNSEISLNPNKFETKNSVLTINEINQQDEDHSDEGEYLPLGNEDFEFKTITVSQPAALIAGTRREPQGPRPISVDKKRFVRNSVYSTNSTTSANVAETDWTYRGEVWMPRVTEPEEVPDVSYQHANDAPKILLEEPCDTLNEMHTKSLSNESTGGNLKKIEDEVALKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6F1</accession>
    <name>A0AAD5U6F1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6F1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="66" mass="7241" checksum="2141B0EEB1E023DE" modified="2024-05-29" version="1">MQEFLSLLIMSLGSEYLCMQKELEPINLTGQGLGGSSSSNKNKNKSDGTGDEIEMKRLNEDSDDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6K6</accession>
    <name>A0AAD5U6K6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA replication complex GINS protein PSF1</fullName>
            <ecNumber evidence="6">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="primary">PRE3</name>
        <name evidence="25" type="ORF">HK099_005130</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GINS1/PSF1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 23">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6K6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11710">
        <property type="entry name" value="GINS_A_psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03762">
        <property type="entry name" value="proteasome_beta_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000010">
        <property type="entry name" value="Proteasome subunit beta type-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.340">
        <property type="entry name" value="Metallocarboxypeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057247">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005339">
        <property type="entry name" value="GINS_Psf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036990">
        <property type="entry name" value="M14A-like_propep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00133">
        <property type="entry name" value="CARBOXYPEPT_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="20" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="21" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="17 25" id="KW-0647">Proteasome</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="16" id="KW-0862">Zinc</keyword>
    <keyword evidence="19" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase M14" evidence="24">
        <location>
            <begin position="98"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="23">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="22">
        <location>
            <position position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAJ3226299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="791" mass="88434" checksum="297D5538D7F7230B" modified="2024-05-29" version="1">MKSNLYEKYQVLRFFIVDNSEINLIKSLLDVDFRLFSEGFAHNTVDLLISLSKFDSLKTSNSNLFKIKYDILISNIQDVIDNERLNSLNFDKTGENGDKLTAEQFFQFYQVQGQHHQFLLSLPGVTNMTIGQSYLGNDISAYKFGNGNQSVIYQGGIHAREWISPATCTFIAYNLVTKKEYSDLLQTFTFYVIPILNVDGYAYTHSPTGDRLHRKNMQPNVGSFCNGTDLNRNFHFKWEGAAVDHDPCSETYAGSEPGSAPETRVVQDFLNEIKPISFIDFHSYSQLWMYPYSYKCGTVNPDSGNQHKGVDLAVKALTAIHGTQYTTGPTCETIYQAVGTSSDFAYGASKVLYTYIVELRDFGQHGFLLPSNQIVPTGEETLAGVVALYRYIASGPETLPPAAKRRAELITRYEDDLVRNVIMETKFLIDDMDHILEGANSVTQESDLNETDINIYQNQTQNSIKMLRNKRCLLAYHQNRVERITAVVKKLGSSPFPLEIKENLSSNELDFAVGYRNLLNEYAKEYPDIEMNRDLNPPKEVFVSIKCNKNLGNVMTETGMKSLEKGSRHYIKRTDIDNFLKLGYKPGEVNLGTTIMAVSFNGGVVVAADSRTTMGSYIANRVTDKLTQIHDTIFCCRSGSAADTQAVADIIHYHLQLYKVQHGAPPTVHTAASLFQQIVYENKDGLSAGIIVAGWDKYEGGTVYSIPLGGSLHKQPFTIGGSGSTFIYGFCDATYKDNMTKEECVDFAKKAVALAMSRDNSSGGCIRLAVITETGVERIFVPGNKLPQFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6L5</accession>
    <name>A0AAD5U6L5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinesin-like protein kif21b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KIF21B_1</name>
        <name evidence="10" type="ORF">HK099_005329</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25764">
        <property type="entry name" value="KIF21A_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="4"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="507"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="973"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="772"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1046"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="973"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="92"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3226224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1589" mass="180896" checksum="1F9DAB3A245AA9B0" modified="2024-05-29" version="1">MSTNVKVAVRIRPLTANELLADAKECVQSVPSQPIVIVNASNILSYSSQQRQFTFDYVFNTLSEQIHLYQDAICPLLENFQEGYNATIIAYGQTGSGKTFSMGTGLEVDVSEENQGVVPRVIKQLFSSMKFRSQLNPNGYEYSISVSFLELYNEDLVDLLNPRPRTAEGANSWGGLAIREDGQGNILWTGVREEEVSGPDALLNCLQKGTLCRTTGSTDMNASSSRSHAIFSIILKQKIWTTSEINTSLVTNEFLGKNVNPQTHSEGSWSSFSSKFHFVDLAGSERLKKTNAAGDRKKEGISINQGLLSLGNVISALGDENRKSSYIPFRDSKLTRLLQDSLGGNSQTLMLACISPRLQNEISLLRLNQKNDPTVSRESVKNKDESTLRSQNDTESKKISQELLDNKSEVVHYSENIEKNVYEENNGENLIWLKRQLQQQLQIQQELEFEIDKFKKLVKNKDFEIEKRNFYQNRIYERSVELNLELHQIMVERDNLLIETAKSHHTVYKNESTGEEKNFPETVESSRPITSVTEKEDMESQNIPNETFLKKINLNAGVDSIIPVQLENGIIPTGFEEEATDIANANTEKKNVNTSKVIDVKSYVNQISDLRFRLSESEDKLCWYKNVFESLSHQQQHKRPTTSTKMKQKLNKSNSNVNFEIELLENIGLKLKNYNTLNKNIVNIKNEFKDLNDFSHEKKLLTALRSDPELKKLLDAKTIEGEDYDMRASHYHPLKRSISSDSDSLRCVTATLKNSNRKNHARATSTSMYLLVNKIQNDIAEHEEIVSKLQRSESEYDAMKKAFEQKLEGLKVQLVQVQRERDLALRRIRGENFTPKEKAGTLAVKARFDKKHKQLEAEIFDLKNKLSMRTTSKSQSENLTKNLLATIQSLKAEKASMTKKLKLEAERSRDLALAKEKEIEKLRLKERKSEETLRKLERNGQLQRLFVSKKSKEDFTASKNKIKNVMDILKRSTNSSNRISKPTVSKHTRHSSEKGTDFSFSTSSLSLTSNFDTSPPSSAPPVEIRAHFKKQMLEKELDGCIRTKRIQFILEELKEKKTRLLNEQKELLAERERCISFEIGKGEVVDPGKQYYMDERLLIIDYESAMLTSRMIELESEKNQNKGNLIQGSDVEEINSFTPSNEDASWENAMNILKSLDINEVQLVSSAYMQEAVKFRVESIDKDLKISEKEKVVLELRAALENMRAAALKTSMQYEKKILELHENAKIAIRNQIESAEKFKDSSIKVERSSPIRSQNTFKSQKSLSISLPPTIKYNPSVLSPNPISPLKIWEKHGNDAAVVAAAVINDALTNSSKTLSSLDDRNNYENLKTFEELFHSVDQTRMMGLKTDPRASFDFSKIYSPKTEENLINYFNSYERPSRPQSAPILMNTSGNFFCKPFPDIKNAYQPPHVSESNQTMQGCINNNNNSLNLNPNSEEKLTILKARRSRSPEKIHKSSIRNLSPIRRSISQSVPFRENQTDDTQNLKKLHNINTLQPTAAVNPSLDYNHQIWQEALNEVQRQECNGDVATIPNNNNVFERLSSKHTKSSKAKVRNSATLFTTNDDGTEYFSNFDPIFNTSSFTLDADLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6P2</accession>
    <name>A0AAD5U6P2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calmodulin-regulated spectrin-associated protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CAMSAP2</name>
        <name evidence="4" type="ORF">HK099_004977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000037">
        <property type="protein sequence ID" value="KAJ3226399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036449">
        <property type="term" value="C:microtubule minus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007026">
        <property type="term" value="P:negative regulation of microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.360">
        <property type="entry name" value="CKK domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032940">
        <property type="entry name" value="CAMSAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014797">
        <property type="entry name" value="CKK_CAMSAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038209">
        <property type="entry name" value="CKK_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21595">
        <property type="entry name" value="PATRONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21595:SF0">
        <property type="entry name" value="PATRONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08683">
        <property type="entry name" value="CAMSAP_CKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01051">
        <property type="entry name" value="CAMSAP_CKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="PRC-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51508">
        <property type="entry name" value="CKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="2">
        <location>
            <begin position="223"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="CKK" evidence="3">
        <location>
            <begin position="1314"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1272"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1272"/>
            <end position="1299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1434" mass="163230" checksum="D2504A39DF1FA026" modified="2024-05-29" version="1">MEILKHTKALYLFYPQVDLLWFSSEEAVQASGAEVNEKNFLEIKKAIKHLELNDSIYDEDILESINGNLNTTVKILDAVKQKCNNSNLNKGDNFDSNYEIMDIHNIATNTIISSLCEGTLYEKATDIVLNELSEGKAEINNAKTKIKFLFLDKLVSKGFFKFKKKLSNSVKEMIGDTSPFYESIHSNIIEAIMAANQHVSMPLRIIEEELNLFDNRNKAICPFDYEDGILIWLNLIRCTFEEKPKEIDDIMKSLKDGKLFLFILQYYNKEPKVARKLEKFTDQSRFVNLNSSSKLKNIQLFLKYSKILNFTEPPFTAEEYCKGGVGFKKIILNYFLEFLKCVEKRHLQVKNGCTAEEVTKKIIVVSRKKLRQVEKLEYEDFSKKHIENCVLAPAAEENGFEKRSEVKKEFCVRLVSNQLTDENFEENNKDAAVFDEDYLANTKKNFSEDNARNVPNELISVSLKENSTKYSGLLENDSNSEKESKRVNMSVMPILSIPVAPDVNSSIKEVSSIECDVPSCSEDFQNNAEVNLSSSSSVETDSNMEILNLKPVVENKIPIQEKGAHNNEAVDKRTFSIVKEKSSTFEESVIDVVVKHDSFERLLHLELPPVESTLLNHSIDILSKKNIEFEDASSIIHSVDLSSCNVDNYQSEKIDANNGQLKKDDGEEVQLEKVDGDEVQLEKVDGDEVQLEKVDGDEVQLEKVDGDEVQLGKVDGNHVQLEKVEGGDVQLEKVDTDEVKISKTNFNKKDVCTTDEYSIIRENKKGIFNKKNEIVVECEISNTFSYKKKTDFTSHVGKKDSLDVTRSTFYGNDSQRVDASFTKLNHIISTDSISNEEVTEIESEVNSYIITDPTQLASKNIAGNELPCEEQSKIELNRKDEKQMSEKIHLNTEIILNDFEVIVGSETSCAGNSADKNSGFEIEGNTDIDSANTISEKLENRPELDSTRKIIPQKYVKISDICNPVGHIDKKEVFVESKNSRPSTANSLTYFVEFDKVNSIASKKNLPKRLRNQNKNSVVLPHLHPSVVPLAQSPPPSYHLSGVNLPSITDKKHSNMDSLEEKVDIGKSFFEDVVFTDPSLNKTKSNSIINEVSNHSKKLKRHAEKHGKISINPQAKNLLFNEFDVDENFSIYVPEGFQCKEFSDNAGYFGDEADELEYKIEGGANLEIFSNKIIPSEDHSKIFELLESRNSSHRKAFIIKTQELSENDLLKAAETTKKENSVELSKRLKLEKKAEFQNTLQHQKKLEIEKLEKLKTDQFYEIENEKRKKELEQKEKLQNKSKLREMKKLMEKESSDTQRKSLTGDSSKYKETKISLPVQKCKNLSNKKLIRNALIHVCLAGKVNENTLTEVLEDLDESKYENFIILFKGLKNNTFRGLYSYDSNLNQVLKTYTESQGPDSLTTDDVIEFYKYDSGSRTFKSIPTKSFGKNNKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Q0</accession>
    <name>A0AAD5U6Q0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the gemin-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000036">
        <property type="protein sequence ID" value="KAJ3226427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Q0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035426">
        <property type="entry name" value="Gemin2/Brr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794:SF0">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12794">
        <property type="entry name" value="GEMIN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04938">
        <property type="entry name" value="SIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="368" mass="42564" checksum="1408054C0D7AAB2D" modified="2024-05-29" version="1">MEYLYHVRSQARNLKDYCTSTVKPVKTSSKSKNVNYILFGLDDNCKEICVDTKNNYDPSDSWKLDFIKGFVARREQLRLYLEKLKILNGDNELNLNITLPKGGKNKWKIFCYGKTAEKNTDELSNDNNDLFFKSSAGAIQEKVHNITMTPQDPPKKAREEFDVQKDLNETYIYENSSAFKVIPSCQGEDKNFFTNISNDDLKSKNNVGSIQAPNLNSALENNTSEVIYVEDTSNFSPIIIEGRLPTINVLFNLTQSNTIALLNWHLEWLQENDSEEADFITEKQCQWIFGLLLHLHTLLTSDEIYVLRELTRKFLKLRENLIKVLDQEIEDDELEEGQCGENRTDDPRIVCLNMFIEIIRNVFGQKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6U7</accession>
    <name>A0AAD5U6U7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000133">
        <property type="protein sequence ID" value="KAJ3223368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6U7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044715">
        <property type="term" value="F:8-oxo-dGDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03676">
        <property type="entry name" value="NUDIX_Tnr3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031804">
        <property type="entry name" value="DUF4743"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15916">
        <property type="entry name" value="DUF4743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="134"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="310" mass="35040" checksum="64ED2457BF608D48" modified="2024-05-29" version="1">MLKIVKAVNNFYPDKILHAPNTSLGFHFIVDGQLVGLITPKFAKQLKKYDKIFKFKDHLIILNKALKTIEERTIQIENVLLELKLNNINEYECLNGWRNERFACYGESSESNAHGGKILLSIERSGCGFFGIRQSGCHLNGYIWDNETLKMWVGRRSKTKQTYPGFLDNLVGGGLGSGSNPVDTIKKEAGEEAGIYEKHLLDKIRPGGAISFYMDHPKRGWMPDTEYIYDLELPKSYIPRPVDGEIKSRLNEFTLEAAICVIDFLIRKGIVNSSNEADYTEIVMGSFSMIGLCKEALLDSMQIARFVSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U735</accession>
    <name>A0AAD5U735_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TOM (Translocase of outer membrane) complex component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TOM70_2</name>
        <name evidence="12" type="ORF">HK099_004088</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Tom70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U735"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 10" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="318"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="386"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="454"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3226819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="594" mass="66544" checksum="B683B64C2135C15D" modified="2024-05-29" version="1">MPSTSDTNVIEKLANFSGRYWKELLLGSAIFLSVGAGVVYLKSSNASKEEHQKISKNGSIKDGSMVDEKIVDTQNLSISELKELAKAAKNKGNKLFAENKFEEATKFYTEAIRLAPDAVYFNNRAACEAHLSYGIAPKVCEKEYKLNTNCDCFLLFLTSALKRDPNYIKALTRRASAFEKIKNYKESLNGTERLIFYKFNAFPYQDYSALCLLEEFKNSVNVESVDRVLKNIGTQKAAEIIKTRKEKLPSDTFITAYMESFRRTSSELSNFLTGSDITMADKVFKKAVMNIMNQEFAKAKSNIEKSIELGSLSKEFEAFAYSLRGTFSFLTGTVEKSMLDFEKSIELDPTQIDSYIKKASVFMEMDNIDKCLEVLKSALEIKSDCADFYYHRGQVRHLTGDLQGAIEDFSKSLAFDPNLVYAKIQLGVAMYKNGQVDVAIETFEEAEILFSNRSEVFNYHGEIYLDQGNETKALECFDKAIKMSPKSSLPYINKAMLYLQVKGDTSKAESLLKKAIEVDPSGDIAFGPLAQLYLTQNRIAEACEVYDKSIASARTEMEIANAVCCKEAAITQVNLASKYPAIMAKLAAQANRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U741</accession>
    <name>A0AAD5U741_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="13">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_004076</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the peptidase M36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U741"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 13" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 13" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="FTP" evidence="15">
        <location>
            <begin position="84"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="290"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="670"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="439"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3226807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="811" mass="88203" checksum="0B17E3F3A7E07B62" modified="2024-05-29" version="1">MKYSLCSAAIFAFASSLNSPLASNQLSTPSDVPKFVQFPASSEIFEIENSSSLLNAIKSEEEQGAIAKTYLAKYLQIEEADILLTSSVTTSNGVANIHFAPTLNGLQVVNSVGNVNIDQNGNVLGVSTSWIPKEVEVKKKDSLTGEQFSATEALKIVANRLNISFDDSRLVQSASFAGTDAVDISGFSNFGAVEVTEKLYRTAENTLEKVYDLAIPLKDNFHNAFVSLSSKEVVGVNDWATHETNVEFKNEPVKRLAKRADFTYNVVGLPNQDFSEGRVIVKNPADIIASPNGWHDDGSGERGTTSGNNVQAQDTQGAARQLPENSSFNFDYPINENQAPVKNWQAGLVNTFYVTNAVHDIAYHYGFDEKSGNFQKDNFQKGGKGNDHVIANTQDGDDTNNANFLSPPDGRSGVMNMYLFTQTNPGRDGDLDNTIVIHELMHGISNRLTGGPNNANCLSNSESGGMGEGWSDALAFILTAKASHTRNDDRTVGAYAVKNRNGIRNYPFSTSLKSNPQTYSDSPEVHNIGEIWANILFEVYWNFVDKSGFSSEFIKDAKSGKGNTDFYQILMDGLKLQPCNPTFVSARDALLQADKARGSKYTCELWKGFSKRGLGPKANSYKNDFELPSVCQGVTTSVIETTTTTSKVATIMETSIEPTLEPTSIEPTIVEPTSETPENTETSVEPTIVEPTSETPENTETSVEPTTVEPTIVKPTLVETTLVEPTSEIPIVTETSVEATPVVTSVVPTTVSQSTPQPNVCAHSVCKRGLPLRKTCNSCVKAVCYYDSYCCRKAWDSRCIFNAKIICGANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U755</accession>
    <name>A0AAD5U755_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L9, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003976</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U755"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="entry name" value="Ribosomal protein L9, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="entry name" value="Ribosomal protein L9, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_bL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_bL9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_bL9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_bL9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_bL9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="Ribosomal protein L9 C-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein L9" evidence="7">
        <location>
            <begin position="10"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL9 C-terminal" evidence="8">
        <location>
            <begin position="123"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="213" mass="24227" checksum="489DA4C9785E530D" modified="2024-05-29" version="1">MSKFRKPDVHVYLLQDIQQLGVKGEIILVPSEAARKYLLPFQLAYYVPRHKGKPILPPDWEPKINPDDIKLEKILPAYDPTGYVEAEGNAASAAEKQSEEELKLQEQEKLKELKLHVNSERIKSLKQHVKKLEFLKVKIGKDTRIYGSISVDDITAEIKSKFSIIVEKSEVTINDVKDEKIKSIGVFKGVIRIEDIAEEVYFDIVVKDATLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U777</accession>
    <name>A0AAD5U777_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ornithine aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ornithine--oxo-acid aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CAR2</name>
        <name evidence="9" type="ORF">HK099_003641</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3227018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U777"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000152">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="756" mass="84932" checksum="D8A50E6706AEFAF7" modified="2024-05-29" version="1">MCRAQYPHILQAYPINVLLSPRTSIIPIISNHWSDRLSCFEESILTEKSLYNLNLISRRFFNETFNIAVINKVKELFSALNNINENLTRHNFCIKGKENGNYLNLNGILTSNLIKWFLSQKIKLGCSGISEEIVYEFSKDAKIIIEQVNLSLGDEFLIDALDRINTSLVTGLKTIKVYSPFQILRYNEYNKKYYYKEFFDEWCVEEPTGNFECYYKKKKIAKKQGGLLSIDLRVNLKLLHLVCRNLIFSKKEQKFSKKFIAVRVEGKYESVNDGLIFKEFVISDVDMPKTLFNGLWIGLFVLCGGVRRSSYKFKERKLNLKRVKLFNRSIATTLAEKVNAGKYSSKEIISLEHKYGAHNYHPLPVVISRGKGIHVWDPEGNKYMDFLSAYSAVNQGHSHPKIIGALIEQAQKLALSSRAFYNSEFSPYAKFITEYFGHEMVLPMNTGAEAVETAIKLSRKWGYMKKGIKPDQAIILACTENFHGRTISIISMSNDETATVNFGPFVPNVGAVCPKTGKKINHSVVKDLEAALEAHGDRVAAFLIEPIQGEAGINVPEDGYLKKCYDLCKKHNVLFIADEIQTGLCRTGKMLAIDHDGVKPDILILGKALSGGAYPVSAVLSSKDIMLCIQPGEHGSTYGGNPLGCAVAVAALKVLKEENMAENVFSFILSALIRGKGLLNAVVIDEDKVGKTAWQICLLMKHYGLLAKPTHQNIIRLAPPLCITEEQLMDGVNIIKRVLEEIPSMKDSDIPGNEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7M9</accession>
    <name>A0AAD5U7M9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7M9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="60" mass="6822" checksum="4D3106E9A4A18F25" modified="2024-05-29" version="1" fragment="single">FSFYYAFIRKITDLASDFKNSREKKDLKAINKMKELLNQSSSNSNHDSSLCSSKLPDTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7W6</accession>
    <name>A0AAD5U7W6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Centrosomal protein of 44 kDa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CEP44</name>
        <name evidence="11" type="ORF">HK099_007825</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Centriole-enriched microtubule-binding protein involved in centriole biogenesis. In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall. Functions as a linker component that maintains centrosome cohesion. Associates with CROCC and regulates its stability and localization to the centrosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
            <location evidence="3">Spindle pole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Midbody</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7W6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030496">
        <property type="term" value="C:midbody"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033603">
        <property type="entry name" value="CEP44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029157">
        <property type="entry name" value="CEP44_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31477">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 44 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31477:SF1">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 44 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15007">
        <property type="entry name" value="CEP44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomal CEP44" evidence="10">
        <location>
            <begin position="7"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF15007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="661" mass="76674" checksum="A85E4EBEBE59E1FB" modified="2024-05-29" version="1">MQHSTGDIKNNLRKLQLQLKSVKYNQQVNFSGLSQGDPGEFLPLIHHILLNFSPKVSNYFLQKDYQLFQKNDKKFLELTFMLCRNEFQFKPKLSQKQFFQFGFAEVKIFFLLDLIKFCKGLKENIKRKSSNQNLLINSNNSNENHNNQNSDSNDILEKEKFGSYNRAIEKEIIINNLNNRGLKNLKKNFFADDFNRGENKNSVEGNIKVFHEHFSPERSALFKRSLQESVLQVKTSNDNRNFTKKLTTNRKFYDLPLQQFKDSESIFNHPPQSRLKNQSPNFSSNLETDEHEMMQDFSVINDDINNSLHEPLISQPLPSMKPSRILTRDIHDLAAKIAEVNLNNKDIFCSNETPFNTFHYNKNHYINENDSLNSEEIHRSLNSIKNDLNNTNNQSFNHKYEFDTNTPINNSKGSVLFDADIKKDEEVGSKLKDKLQNNENKELLGRISEIENNIRNMFCDFNSRIEKIEVALTVNEKKNFLLDLPSSAEKVAKSISNQTPTEFSNVEKGLFNNREKLLVENVNERTPPRSYCEHTKNEYHENFLNPVEKVSDEILNETNAGSILSRVEAQGSFINVLEPVNIEVTDKFDDRNLNNGVVFNNVENSIEQRKQVKGNDNEGVSLKRISEETHKNISDSLNCKGEVLIRSIEEKIQRAREKLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Z9</accession>
    <name>A0AAD5U7Z9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Guanine nucleotide-binding protein subunit beta 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GPB1_2</name>
        <name evidence="7" type="ORF">HK099_007325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Z9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000020">
        <property type="entry name" value="Guanine nucleotide-binding protein beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016346">
        <property type="entry name" value="G-protein_beta_1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19850">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25391">
        <property type="entry name" value="WD40_Gbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002394">
        <property type="entry name" value="GN-bd_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="55"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="143"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="184"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="226"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="312"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3228044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="344" mass="37818" checksum="33134C27347A3F91" modified="2024-05-29" version="1">MADIAEKIAAARKEAEVLKERIKQKKDALADTTLKVVATDLEQLPRIAMKVRRTLKGHLAKIYAMHWASDRRHLVSASQDGKLIVWDAYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTKEGNVKVARELSAHTGYLSCCRFISDRQIITSSGDMSCMLWDIDAGMKTLEFTDHTGDVMSLSLSPDKNVFVSGACDATAKVWDIRTGRCVQTFTGHESDINAVQFFPNGDAFGTGSDDASCRLFDLRADRELNQYTHDNILCGITSVSFSVSGRLLFAGYDDFNCNVWDTLKGERVGVLAAHENRVSCLGVSSDGMALCTGSWDSLLKIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8E0</accession>
    <name>A0AAD5U8E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAS-associated factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FAF2</name>
        <name evidence="3" type="ORF">HK099_000807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000120">
        <property type="protein sequence ID" value="KAJ3223695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8E0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="127"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="218" mass="26270" checksum="744BAFEBA8B9AB7F" modified="2024-05-29" version="1">MDVEPKDRYLRLQHKLKKFSTNPLPDFLKGTYTEVLSQKIGNELRLLRQEQAEREHSRMIREQQDQAYKISLQKDQEKAKELEKEKEILKQKDQLKKEKLRRKENFKLDRKNLILELKRNQKSEPLLSNTTTKLSLRLPNGERIIRVFDLNDTLQDVLNYVLTLEFVELEWDYYLIRTFPKFEFNDLTLNLKDASLFPNGSLIVEKREFDELLDEELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9C5</accession>
    <name>A0AAD5U9C5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">60S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_006858</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000062">
        <property type="protein sequence ID" value="KAJ3225400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9C5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000004">
        <property type="entry name" value="60S ribosomal protein L11, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_uL5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057266">
        <property type="entry name" value="Ribosomal_uL5_euk/arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003258">
        <property type="entry name" value="PRK04219.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="13">
        <location>
            <begin position="66"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="20174" checksum="329A8A17B4B88430" modified="2024-05-29" version="1">MAENTKASNVMRELKLEKLCLNICVGESGDRLTRAAKVLEQLTGQTPLYSKARYTVRTFGIRRNEKISVHCTIRGPKAEEILERGLRVKEFELKKKNFSDTGNFGFGIEEHIDLNIKYDPSIGIYGMDFFVVMGRPGLRVGRKKHCHGRVGFPHRVTKDETISWFKKRFDGIVLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAF2</accession>
    <name>A0AAD5UAF2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAF2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="417" mass="48619" checksum="04C10C31187BFCDC" modified="2024-05-29" version="1">MIGIRDLSKPTTIDLNSTQKFIPSTLCNNISRPNSINELDEAMKKMDSQNGTSFYNWIKSEENIGYICTYKRDIFEENFENNPKQVFIAVKWLVSGWSVPSVSEFLLKMFYHWKLESKKFGALVNCICNGFQTKDNSSTLLETPEFNKRFEKKKVLDLLHVLLIGENAKSTSKFLLNFTKSFNIVKGFGKDNFEDNKVEQKDSYPAADYKTKSWDRFEILEVVKGLSFRLQWDEAFLKQLLIEFVQNSPLKNTEKKQLDLIQLIKFKFHQESTSPINSLDVSPPFSNLTDTDESNEIKLQNNAEQYIIKNNAFKFTYRYKINFFIQLFDTILIELECMELSLILEDLQILKNNFLNNKNFNELGSDECSEDELIDQDELLLKGLIKNKELRLRSFSSQGSCTTNRIDSRLSFQDLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAG6</accession>
    <name>A0AAD5UAG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004875</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000036">
        <property type="protein sequence ID" value="KAJ3226422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAG6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070552">
        <property type="term" value="C:BRISC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045739">
        <property type="term" value="P:positive regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026126">
        <property type="entry name" value="BABAM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15660">
        <property type="entry name" value="BRISC AND BRCA1-A COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15660:SF1">
        <property type="entry name" value="BRISC AND BRCA1-A COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="153" mass="18108" checksum="95406D8761DCBFAF" modified="2024-05-29" version="1">MFQSYSRLDMIKRYLKKFVWHKNSLNENHEFGILVLTTTCLWKLNLTNNVEKVTSAIGKLEFDTADYAKDLNAYYHDFVGYCELGDVFKTLESEIDDDNAYLQLILFYSRSYVIPDIPSVDLLQKFHNSGKFVYDSIFFHEKVNNMVNSYFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAV1</accession>
    <name>A0AAD5UAV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ADP-ribosylation factor-like protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ARL3_1</name>
        <name evidence="15" type="ORF">HK099_004185</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAV1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04155">
        <property type="entry name" value="Arl3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000281">
        <property type="entry name" value="ADP-ribosylation factor-like protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044612">
        <property type="entry name" value="ARL2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45697">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="171"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00040616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3226767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="653" mass="74173" checksum="79BEE75C18A0563A" modified="2024-05-29" version="1">MGLLSLLRKLRKQDREVKILLLGLDNAGKTTILKRLASEAIQDIKPTQGFNIKTVVQDGFKMTLWDIGGQKTIRPYWRNYFESADILIYVIDSSDRRRLEETGIELHSLLEEAKLVEVPLLVFANKQDLMNSLPADEIAVGLNLNSIRNRKWQIQPCSAKNGDGVSDGMEWAAAKSMQEGSTSSTQKIYFDKYVVEKSLGDGCYGKNQKRNQDSEAPLSSPIVTLLDVMVYRCVLLNYITNTLKETDKEIILVMEYVQGGELLNFIVAQKRVEERFARRFFRQLVSAVDYCHKNSVIHRDLKPEHLLLDQYQNVKIVDFGFVNLFDPDQKLNTFCGSPFYASPEYTGPEVDIWSMGVILFTMIGGQLPFQDDNKAELCNLIANANFKYLVFFRMVIKKMVFSLIENSEAVDLIKRMLVANWRERITIAEICKHSWTNEGYSEIPNTYIPPRYSFNENSVLDDQPAFPVYHLVKEHLERNSTSFTELEQHSSKETTTKTMQGVVLKYSTTTVIASNSNIHSSSTVYSSKKSKHELTSCCDSSATPTIASSLTEGNNPETAPSVNSLEEVISPLSKSRKHSVFQHWINTAILLSNCDRSRSENLDTNCNQTFFHGLLEEGGDLIKRRRSPYFERLSLIIANATVMLKVKLFNGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB11</accession>
    <name>A0AAD5UB11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ABC transporter substrate-binding protein PnrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003136</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB11"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050957">
        <property type="entry name" value="BMP_lipoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34296:SF2">
        <property type="entry name" value="ABC TRANSPORTER GUANOSINE-BINDING PROTEIN NUPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34296">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN MED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="657"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="750"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="812"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="856"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="930"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="958"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="997"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter substrate-binding protein PnrA-like" evidence="7">
        <location>
            <begin position="10"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1102" mass="124904" checksum="E93D2AD70F2DCD7F" modified="2024-05-29" version="1">MGVYYNLYDKLPQSFPDANFTVIDLIDGLPSEYPNLRTVIFAEEEAGYLAGVIAGLMTNSQIVAEIISTATLPYKRYSNGFKQGVLAVCPRCNVIRKFNLNSSINASINFVKDLANKYSFDILFGVGGDGSRAAIVWASQNNIKVIGSETDESGTTLNFPNRETNLGSVGKRLDFASTKSIKQGSTAFKSGIEIWDLDLGGIQLTSCIPETCPLYSAKTIRSRKNSMSDCTTTDFVTKQTFLNDITNSIRSHTINIGVDFATGDLMELKKQKKNEFQLSTPFGIRPSELKSFTFTKGTEEFYLFGGINNNGVVVGDLYKFKYLTYDWDKVVYKDDENKPQARYNHGAFLLGMNSNFEESDMLLSINIKKLNARSSITVKVVETEGLQPPALSDPFFSVLNSTLILYATSKWEIIIPTGVNPQGRAKGKMLTIDYRVLIIGGFNATGSLQSTVLYDSIKNRWDYENTNKLPTPLDSFGAFVYRQKKTSCLFVDIFSLCPYEDLPQIMIYGGSNNNILSNELLIYRLENSIENILICKRGFYSTIDAFNRPICTECPSGMYNTLGDNICRPCPEYGADKVYAALNSWQDSFSYKNSTPQIFPCKTGTCCQKSDGCDVNSMCTGSGVTQTTGPLCSECVDSRYAMWSDNCIYCENPNTSIYLFVIFLVGFLLILILVFVPYVASCYNGWFTSNCIFVYQVMGLTSHLPASEFINTLSNICSLDFETILKVISGHTSNDHRICLGRYNGVERAAITLIMVTVFLLQFFFIYSTAHFWIKTKENGNKFVLKLNRYIPKYINNLRIIDYRLAAIQIGMFLYIPLSSSATQLLSCQAIIYNGKEMSVLSKFPDQYAQCWSSKHIPYVVLATIVLFFLVIIVPGILIYKFMVVKAHLKTESMFTSLSQSYEDDCSYGSIVEYFERIAFSFVLLSEEEYKCWSILMILLLILYLQKFKAYKEWKENFTKFIFLICMIGTAALEINFNRVCVNKKCNSFYSDFFTKWQITFFFFPTFIIALRFVLKVNEILGLHKKIYFYFIYRKTKKISVLDEKIVNSDYTMENLPAKIKDNEGLELKQTINTNLGEAEMLNCDIEDIVFCSVNSLIHKEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB70</accession>
    <name>A0AAD5UB70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB70"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="224" mass="25688" checksum="D50FE3642ABE487B" modified="2024-05-29" version="1">MSTMQNHPSTKKKLHKDNLESSLPNLTIQTNLKRKNSHNQDSVERIIKKTLNDAQLKQQQPTFTQIQLPTPYGENSSEVVENLGKKKFLFSLTQDQINAYLPSPESGNRKPSLVLQTQENGRRPSLLLFVPSRRGSKNIANLTANKEDSNENVLSGLNEKLSDQQVSFQDFKSLNQKKIELVEDKIELKEKNVLSHSLRENSLNDMLERSKAEEKPIVSWRPWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBZ1</accession>
    <name>A0AAD5UBZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cleavage and polyadenylation specificity factor subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nudix hydrolase family. CPSF5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005849">
        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18871">
        <property type="entry name" value="NUDIX_Cfim25_Nudt21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016706">
        <property type="entry name" value="Cleav_polyA_spec_factor_su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13047">
        <property type="entry name" value="PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13869">
        <property type="entry name" value="NUDIX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017888">
        <property type="entry name" value="CPSF-25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR017888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="257" mass="29573" checksum="4D68C761B11B0AE1" modified="2024-05-29" version="1">MSTKPTINLYPLENYTIGQKDPQPEDDPSVAARLNRLQHEYEKFGMRTSVEGVLMVHEQGHPHILIPGDNLKPGEDELQGLKDRLNQRLAPQKENKEENKEDSNKMNGTKIDSEPPPSNPISDEDKIMEKGDVELDIKNNADNEKASYDEEDGDYEIGELLTIWYRPNFETYMYPYIPRHITRPKETKKFFIVQLPERKVLSVPKNMKLLAVPLFELHENTARYGPQLAALPHLLSIAIFREGCLKSVSYHLPQLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTF8</accession>
    <name>A0AAD5XTF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bulb-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007759</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000785">
        <property type="protein sequence ID" value="KAJ3212318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTF8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00028">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="entry name" value="Bulb-type lectin domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bulb-type lectin" evidence="2">
        <location>
            <begin position="90"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3212318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="201" mass="22455" checksum="A6F47FD6F0963F79" modified="2024-05-29" version="1">MTRIDRDETRVESKEARHEKREQRRRDRMEGRDRSSSSSSSSSDNEGRLGGMMHKKKAATTPHPTPTHQPPPMAVHQDKNLESDRPDLVLDTMEVDVRLTEGQVRKSKGKNVVLNMQGDGNLVLYGPNSKVLWAAGTNKNVKGNFAILQRDGNFVVYNHQSSPLWASNTAGKGSPPHRLLLQDDGNLVIYDAANHVIKINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUI3</accession>
    <name>A0AAD5XUI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DSC E3 ubiquitin ligase complex subunit 3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001928">
        <property type="protein sequence ID" value="KAJ3200318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUI3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044695">
        <property type="term" value="C:Dsc E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045226">
        <property type="entry name" value="Dsc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025390">
        <property type="entry name" value="Dsc3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049:SF1">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN YOR223W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13373">
        <property type="entry name" value="Dsc3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSC E3 ubiquitin ligase complex subunit 3 C-terminal" evidence="1">
        <location>
            <begin position="173"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="235" mass="27001" checksum="7866C0522FC0C1EA" modified="2024-05-29" version="1">MSLDASSSSTFENIPLLPLIQNDSFQAKVLTSNGKTINLILKKNERVIDLENKLLETFLTKNDDNDNQQLQQNNKKLIKKFRFILNGKILKKNELVNKFNLNFLVLHCSITEEEDEKFDESVLKKKGKEREVDIEENENLLSSREFQNSNTTTITSDTAVISSSLSQTSPEARGFERLRSIAGLTEDEVNGLRERFHLLRDNEDVHNNNNLTNAEDEWIDNSANGNKKKKKKLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUY3</accession>
    <name>A0AAD5XUY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">B-related factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">BRF1</name>
        <name evidence="13" type="ORF">HK099_005432</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000421">
        <property type="protein sequence ID" value="KAJ3217558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUY3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20553">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20554">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000002">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000007">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011665">
        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Cyclin-like" evidence="12">
        <location>
            <begin position="101"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="12">
        <location>
            <begin position="197"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="427"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="429"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3217558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="495" mass="55695" checksum="49DA3DCE39CC96A2" modified="2024-05-29" version="1">MVVIVQEVRLLNVSIEVGTLDNTKSDSDTAVLVKSCGTVLEENEIIAEVGFTEKSNGAAVADGFLIAHGQARAKSGGYNKFSMASTDDSDKHQITLANGNRKIAEIAHGLRLSQRHVEMAERNFKLAVNYSFTKGRKIAVVAACCLYIVCRLEKTSHMLMDFAGNLHINVYVIGTTYVKLVQILHLREKIPHIDPALYIARFCALLQFEDKVNVVISDCLRLISRMDRDWMALGRRPAGICAAAIFIASRMNGFIRTKEEIVHVVKICTGTLKSRLSEFGQLPTSKLSVDESRKVWLESAEDPPCFMSDSKKNLKKVLIKNGSEKVSKKRKHLNAKDSSDEIEKNIPITPVSLEPDIVEEVEEEEVIVKSMMIELEKPFALNQLKALDKFNDDDLSCFDTDPEVIGALNSELEMEFKKEVFNRLNRNYTENRDPKKKGDTEQKEKKKRVKKSHNQQIPLPPSNSLMDSVHNMLKVKAPQLSSKINYEVFNKTLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV73</accession>
    <name>A0AAD5XV73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002252">
        <property type="protein sequence ID" value="KAJ3198834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV73"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3198834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="182" mass="20709" checksum="DFE2159EBF516751" modified="2024-05-29" version="1" fragment="single">MNTNHKNKKNFRNSIISEFGRLKDNPNENIFSEDLEEPLNLEFNNSKQEKFNLKRNFSKNSKMSKNSKHSKSSTSKSFIIHNDVTGKLNLPFFFGSHRLSGLSEFFNFSKYLGKRESVSSIKHQKTDATSSSVGNTDSLRPTPSFSNSVALNVQTVADIQVNIDNLNKDESESNFLTYNENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVH8</accession>
    <name>A0AAD5XVH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like modifier-activating enzyme ATG7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 10">ATG12-activating enzyme E1 ATG7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Autophagy-related protein 7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-like modifier-activating enzyme atg7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ATG7</name>
        <name evidence="13" type="ORF">HK099_002537</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001848">
        <property type="protein sequence ID" value="KAJ3200716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVH8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019778">
        <property type="term" value="F:Atg12 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019779">
        <property type="term" value="F:Atg8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000243">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.100">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042523">
        <property type="entry name" value="Atg7_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="12">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="11">
        <location>
            <begin position="113"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3200716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="419" mass="46206" checksum="CD31B6F5F51C71DE" modified="2024-05-29" version="1" fragment="single">LTIGFVDSTSLECHPGWPLRNLLILAKKRWNIKNINVLSFRESLSDSKIIISKSLVFKVVLPDGEFKENEVPLAVGLEKNTNGKLGSRNVDLSAVMDPKKLAETAVDLNLKLMRWRILPELNLEKISATRCLLFGAGTLGCYVARSLMAWGIRDITFVDNGKISFSNPIRQPLYEFEDCLTNGEEVKFKANVAAEKLKKIFPATNSKGHVFTIPMPGHHVSETLQSETLKVVEEIEELIENHDVIFLLTDSRESRWLPTMISAAKKKIVINTALGFDNFLVMRHGVRLDKLTNDDQSTKTFNSTSTLSGSELGCYFCNDVVAPSDSLSDRTLDQQCTVTRPGLSALASGIAVELLMSVITHSKGPLANSSVTISPTQSLPIDSSILGLVPHQIRGYLTHFSNLLITGKSYDKCTACSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVK1</accession>
    <name>A0AAD5XVK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001065">
        <property type="protein sequence ID" value="KAJ3207295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVK1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3207295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="261" mass="30227" checksum="12F97034E8B2BEFE" modified="2024-05-29" version="1" fragment="single">MFNLNTCEWKRPSLVGETPANRAFHSSCYYQKKNQIVFFGGVNSNINGEKIFLNDIFFLDIGENKWVYPPIKGNFYPVARYLHSAAIYDDKLIVIGGQSPSISEEMTNTLEILVFDLLSYAWTSMKQASFSSTYGHSSVILDGNQIISFGGCEVQKEEQSLNFKKNDFYYCEIGPLLPVDKLSFLKKNKTLSWVDKFLHLMDRSYRLFFRIKEKDDRLLDWIKLYEGGELSYYFGNFDDSLSYEFKIQAWNKNSDAASIDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVL2</accession>
    <name>A0AAD5XVL2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001759">
        <property type="protein sequence ID" value="KAJ3201249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVL2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042190060" evidence="1">
        <location>
            <begin position="18"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="222" mass="22580" checksum="94CEF20433779E8D" modified="2024-05-29" version="1">MKYTATLIFSVLSLIQSARIPKGEAGTKCGGIAGIACNEGLKCQVDDKNTADAFGICVSIINGELGSQCGGFAGFPCNDGLECQVDDVHIADAFGTCVAKVTINGQLGSKCGGFAGFPCNHGLECQVDDIHTADAFGTCVAKVTINGQLGSQCGGFAGFKCNAGLRCKVDDKHTADAFGTCVAIPRGAKGSQCGGIAGFKCNRGLKCVITEKGVADAFGICQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVM8</accession>
    <name>A0AAD5XVM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000308">
        <property type="protein sequence ID" value="KAJ3220310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070692">
        <property type="term" value="C:CTDK-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032786">
        <property type="term" value="P:positive regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042326">
        <property type="entry name" value="Ctk3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024637">
        <property type="entry name" value="Ctk3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024638">
        <property type="entry name" value="Ctk3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28291">
        <property type="entry name" value="CTD KINASE SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28291:SF1">
        <property type="entry name" value="CTD KINASE SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12243">
        <property type="entry name" value="CTK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12350">
        <property type="entry name" value="CTK3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="255" mass="30519" checksum="3927776704D5344F" modified="2024-05-29" version="1">MDGFQIRIEFKELLSKLTVRPESILKTAQFAIDYKSFHENLFDCIFEHVHTSNVLERLNLLYVLDRMVSMSNKTKFQGYLDLVSQNLIDIVDNIVPNNSTGLININGLKKVLKKWKVVLKDSSEKFEEIDKKLELMEQNDNNNHNNDNMNENNKIKPDHQHHSLQQKRKHSKVNNVEKMTDDVIMKRIEDDRERHKRIKEEFWLTFRKQPELVFDRDFESDPEFNDCWENFSDLNENDKILLENESLKYKDIMKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWH2</accession>
    <name>A0AAD5XWH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001126">
        <property type="protein sequence ID" value="KAJ3206425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWH2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3206425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="108" mass="11176" checksum="B917ADDF80AD150C" modified="2024-05-29" version="1" fragment="single">AAQKPASPQQKLATPASKPIPAAQKPVSPQAKPMAAVQRPASPQQKLASPQQKQAAPAKAASSKPQQNAPAKATKLNSPVEKLNSQKTTLPSQKPLSAQSNKSTKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWN4</accession>
    <name>A0AAD5XWN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000643">
        <property type="protein sequence ID" value="KAJ3214175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWN4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="181" mass="20362" checksum="98F109115F8A2FAB" modified="2024-05-29" version="1">MSTIIISSPSTESASMMTEQTQNLPVKNTQVNLILTVISLTIILTITTLSGLLLVLKYINKKNLKKRMLNSKENNLEKSSNLKNLKDSILSSSKSNLSKTKSLLMSKSDDDEDSDSEELNQIFKVQKLSPELHLATRVYSSRLSSYQQSNHSQLSIPATYYVPAVFNQPKIIVNEYVNYDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWT2</accession>
    <name>A0AAD5XWT2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidinol-phosphate transaminase</fullName>
            <ecNumber evidence="4">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HIS5</name>
        <name evidence="14" type="ORF">HK099_006789</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000607">
        <property type="protein sequence ID" value="KAJ3214605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWT2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885:SF2">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="13">
        <location>
            <begin position="51"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3214605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="381" mass="42672" checksum="648D07A2E67F7025" modified="2024-05-29" version="1">MNIKEVLELARPNILKLTPYRCARDDYSTGILLDANENNFGNAAHGQEELHLEKYPDPHQKELKSLFKNFRNLDSSDRLFFGVGSDEGIDLVIRVFCTPGKDKILICNPTYGMYSVCAQVNDVEVVKVPLKVDDGSFQLEVDKIKQAIDVEKNLKVCFFCNPGNPTGTLLRRSDIIEILQYFKGIVVVDEAYIDFSYDENHPLETQSFTNAISKYPNLIVLQTLSKSFGLAGIRFGVSVSAKEVAQLFNNTKAPYNISTLTHLTAKTALEEAGIKLMRSNLNKILMERERLTEKLKSIKRIGKIKGTNDANFILFEVLDKAGGKPCNSSAVFVYKKLADDYKVVVRYRGTELGCEGCLRVTVGTPSENLEFLNKLMLVVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWU2</accession>
    <name>A0AAD5XWU2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">COPS2</name>
        <name evidence="9" type="ORF">HK099_008566</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000956">
        <property type="protein sequence ID" value="KAJ3209162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWU2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000006">
        <property type="entry name" value="COP9 signalosome complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="259"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3209162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="465" mass="54094" checksum="6DBC6B4F20D0C17B" modified="2024-05-29" version="1">MSDYDDDGDFMVEDDADSFQYDNSDDSGEEEPDAILENKYYNAKAKKTDEPEESIKDFKEVVDLDVDKTDWGFKALKQIVKVSFKLNKLDVTLSHYIKLLEYISLQKVTKNYIEKSCNTILENVANSNDMNFLEKFYSLTLECLESVKNERLLQKTNLKLAKLWLDRKEYQRLLSITRNLYNSCLLEDGTEDQRKGTLLLEIFALEIQMYTETKNKKKLKALYQQCLAVTSAISHPKIMGVIRECGGKMHLSEGEWDAAQTDFFEAFKNYDEAGSEQRIQCLKYLVLANMLMQSKINPFDSQETKPYKNDKEIIAMTNLVDAYQQLDLKTFEKILKQNKKIFFEDDKFIKFHIEGILKKLRSQCLCLLIKPYTRIELSFIERKLNVSVEEVEDLIVGLILDEQVKGRIDQVDQILVLYERYIFITNLATEKIFLRDGDDSLQYEACGKWASNLDSLYNSVIGKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXF4</accession>
    <name>A0AAD5XXF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein translocase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TIM44</name>
        <name evidence="9" type="ORF">HK099_000626</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim44 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001152">
        <property type="protein sequence ID" value="KAJ3206102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXF4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tim44-like" evidence="8">
        <location>
            <begin position="270"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3206102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="426" mass="48723" checksum="710D0384E4B212FE" modified="2024-05-29" version="1" fragment="single">MSNFLFSGFSITTKHSRPINKLITSNSSLNLGINLTQTRNLNLFAEFAKSVKRQYEENKQLKENIKQLSDESNRIQQSEAMIRAKKAMEKTSKGTSKVVDGIKFGASKVGEAYESTMETEAAKKTIEITKKVGEKVSEGVHYVADPILETEAAKKVSSGLKSVKEEVIDTQTTHRYIEYAPKEERKKKLQDRLTSTDPLKRIVQANPEAGQNIVIHKETKMNQRWADFKENNILFQNLLKVQKTVEESENPILERFRDWFSGMGEESEEAQVVKAFRMCDPSFSLDSFLRDATQFYIPDIMEAYLKGDEPVLKMWCSEQLYAQLMAGITSQKTQGLISDSKLLDIRKVELLQTKILENDIPILLLEFNTQEILLFKNLKGEIVLGNEDNIEHARYRMVFTKDQIIDATAEINPETFGWRVLESVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXI0</accession>
    <name>A0AAD5XXI0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside diphosphate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NME5</name>
        <name evidence="9" type="ORF">HK099_005558</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000439">
        <property type="protein sequence ID" value="KAJ3217184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXI0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22970">
        <property type="entry name" value="DD_NDKH5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161:SF3">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3217184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="192" mass="22072" checksum="9DA17EFDB313B4AC" modified="2024-05-29" version="1">MERLLFLLKPAILPEADKIVYKLEQNGFHILEKSQIRLTAEQIKNLFFNEEEEIQEAFLNEYLSGDIVVLILEKLSGFQEIKNLLGQADVETAKEFTPNSLRAIYGDLFYASLDFPQAERDIRFFFPDAYVDTFPAPNCDKSFLENSIYPVLTEGLTYLCKEKPENPIKFLGDWLLENNPNVPKIKEPSTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXJ9</accession>
    <name>A0AAD5XXJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF726-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000724">
        <property type="protein sequence ID" value="KAJ3213310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXJ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF3">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="281"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3213310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="55673" checksum="441E0A19826116BD" modified="2024-05-29" version="1">MSLQLGSVLLFKVQDFAPIFEVEYSWIFPDGDLIPKMIEGVEVLVDVVLVEVVIELVVFEEEESVVLVAVESVVFVVSVVLMEVVLTEVVFVTVIVFVINKSFLVNHFSDFLGKGLALAIIKIIEINMRYVLADTLSAQSQENRPVTLIGFSLGARIIYCCLQELAKQGKYGIIEDVYIFGCPVIASTKEWQEVSSVVAGKITNGYLERDWVLGVLYRASAASWSSVAGLSPIENVDGIVNIKLDGVIDGHLEYRLGMPKVLQHCGFKITKDYFDDDDDREEILKEELRVIKQKKEEEELRKKLEKKKREEENKEFGLKKGWFGKNDEITPKEIKSTLPALLTLKEIKSTLPTLLLSVEDRNDDEAGKSFTPKELKSTLPTLKVVSTSTTNNVTSENLEKNSHSSHSYIDVSSPNNFGSNTHVDSVIEDKFVGLTGEELEKELVKHASTQKDVYFYKSGAGDKADLDNDELEDLHNPLDLSGLALEDGGGLVWDQNQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXQ3</accession>
    <name>A0AAD5XXQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000086">
        <property type="protein sequence ID" value="KAJ3224635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXQ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964:SF113">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="83"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="225" mass="25269" checksum="4C57C44E70B66A9C" modified="2024-05-29" version="1">MEPASDNEELKNTTALTESTESKVDHTQELASESIQKETTLEADVSNVKISNPIEVCQQPISTAETANYSSEKNESTTLLKKRRIIIAVDQSSHSEKTINWAINNFINPETDKITLINVRSDVNDFFRLFTEKKKSTFEEELENQYRSESHNLIKTFGSLMIRNKISCKGFSMVGDARELIIKKAEEEKADVLIIGCKGSGKLNLFGTTAEHCIKNCTCPVICIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXY5</accession>
    <name>A0AAD5XXY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000923">
        <property type="protein sequence ID" value="KAJ3209782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXY5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3209782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="158" mass="18271" checksum="63647FFA3956F617" modified="2024-05-29" version="1">MEEDGAIHLKRLFKVSYSNLTEDQAVALIQMYRIGHFKRQEQRQGIKLRREKMIVAKDKESGGFEESSIVDTISEIPEEPIIVVECKSENVKRCFKQCILAFKDVYDKSNKPSYGILSTGVSWSFIKYSDNDISEEVTTIFPRMSQQKRDGLIKIQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYC5</accession>
    <name>A0AAD5XYC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000044">
        <property type="protein sequence ID" value="KAJ3226107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYC5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="109" mass="12204" checksum="8BAC5B651F7E3B02" modified="2024-05-29" version="1">MTGSVSTILNGLLSFMLEDTSTTGSIITTKSRELGIQEIKNFENSLETSNNEIQNEDRTISAIHDGNLVNRKAQIKLKKDYNTEVNNIRQGTSSSFCYLFIVKVSERIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYJ9</accession>
    <name>A0AAD5XYJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYJ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="194" mass="23164" checksum="CF8CD77BA01458A5" modified="2024-05-29" version="1">MTILIDIEGDQDECIDVSPVGFEKIYPETNTENTNTNIDHEKLNFIKMMRLKFCIRPDFEITKNIIFEDGSLNQDYFRPKKNSIMKQEGEQRKWLDSHRLLLIKGIEKWGIGHFREISDEFLPDWQPNDLRIKAMRLIGRQNLQLYKDWKGNEDDLKREYEKNKGIGLKYNSWRGNCLVYDDDGKVLEEIKRVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYQ0</accession>
    <name>A0AAD5XYQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Peptide deformylase</fullName>
            <ecNumber evidence="2 7">3.5.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Removes the formyl group from the N-terminal Met of newly synthesized proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-terminal N-formyl-L-methionyl-[peptide] + H2O = N-terminal L-methionyl-[peptide] + formate</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2 7"/>
    <dbReference type="EMBL" id="JADGJW010000657">
        <property type="protein sequence ID" value="KAJ3214005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYQ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.45.10:FF:000003">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458:SF2">
        <property type="entry name" value="PEPTIDE DEFORMYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3214005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="201" mass="22830" checksum="8E4861B0987C063B" modified="2024-05-29" version="1">MGLISKLRYFISKPPKVLSVGHPILRIKSKDIPVSEVNSSKTKEVISQMKKVFQSPFAEIVGLSAPQIGHNLSIIAYQINSKAQEYVPTVGKKEVPLTFVINPKVTLLDDEKTFIPSYEACESIPQYNCVVSRSNNIRFEGFDVNGNKFEKHVSGYLARVIQHEFDHLQGILITDCMEKKSLRHNKYIDEYEMYISAGHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ04</accession>
    <name>A0AAD5XZ04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003092</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000208">
        <property type="protein sequence ID" value="KAJ3221798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ04"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="205"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="303"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="533"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="475"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="475"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="486"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="610" mass="66655" checksum="358523E252FCCEB3" modified="2024-05-29" version="1">MTSTTTNIIKENVEISTAIKSDNVPNSTSTNLLKRKVLSIDDEEKNENEHNDILNLDFGLSSDQVEENSISDAVKKAKITENLDEENTFIPFEEDFSEEVECKSATVTESIETCNLPVTPLLPIEDVKKSNELETSLNDENVINNSIDEVLPEAEALSATEGAVVTEDSTALDDSEGEITNKITPSIPAFSPLTDLTPANPNDSKVLSVRALISSKDAGIVIGKQGKNVVEIRETSDAAIVVSGQAPPNAERILTVTGTVMAVSHAFSLIGQKMIDNNDLDDSEKKRKFDGTANGDNVVQKEDKIALRLLVPHARVGAIIGKSGATIRDIQDKSSCFINVSEDMLPGSTERAVTINGPVDGIRYSTRVVAQILLDNAGRSTSSVILYKPPSAINQVKPRPLPNYTPQYYQARPILPVQPQYSYQQPQQPINSHPQQQMVYSGHQQYTYSQPAYRPYFPPSVQHRSATTYSSPYTTQYQQPAQTTASSFAHTQSQYQNAPQSNRNPQSNSQHHLLRPQHHSAPVPNSATSANATPPQHQIVVSKVLAGAIIGKGGIRINEIRNLSGCTIKIEDAANPNDRLITVHGAPEGVQMAMFMFQQRIESERAKGMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ22</accession>
    <name>A0AAD5XZ22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylinositol 4-phosphate 5-kinase 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PIP5K9</name>
        <name evidence="4" type="ORF">HK099_005298</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000404">
        <property type="protein sequence ID" value="KAJ3217927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ22"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="PIPK" evidence="3">
        <location>
            <begin position="1"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="604" mass="70089" checksum="C18AF7E0DCD08C05" modified="2024-05-29" version="1">MLYATLLILTLSLLLFFGIIIPFLKQRKAKLFNFSNKDEPHHFKLLRKQLSNSLSCKPYDTSILTVHNPNTFKEIRNLHLDESLALSFSKPFKPRKSEGKSSSSFLETSDNLYLIKTLKASQELNTLKLFLFNYFEHIKKFKHTLLPIFYGLYTFKKPGYEFSFVVLKNLFPKKFVLSSKFDFKGSNLGRKALHYNSLEAKINYIPSVIDEENTSNTENDLFCQNEQTLKELDFKLLFDHGKQNKFKLGQINKDKLLTQLKIDVDFLKANNLIDYSFLVGVYREKKPMNSYQKTLAKFLSNINEKYKLLSNNKRHTVHFPSLAALKSLSKSKLSKEIQKKNSMSSITENENILTETSLLLSTKRLNNGGSSFDFSNKKTPAYISNKLEVDLEKGFNRENYSKQETKSYGSVCIESQPFHKSFEGGMKSVDFSNDEMVMFEEEGEILYEIYFVGLIDILQTYDFSKKLERTLKRQKLFSDQLYNNSNGSFKFKKKRSVASISSVPKSVLGVFKKETTESNEDDYETARLPHFNNIRRNSAAPAPTCSGDLRKSVVKKNSHVIFDKKKRHSENSFWKSFEFKLEPSVEEPDRYGERLKNFIDEVFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZI5</accession>
    <name>A0AAD5XZI5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cilia- and flagella-associated protein 43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">WDR96_1</name>
        <name evidence="13" type="ORF">HK099_001891</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CFAP43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000159">
        <property type="protein sequence ID" value="KAJ3222786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14885">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25828">
        <property type="entry name" value="CC_Cfap43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BTB" evidence="12">
        <location>
            <begin position="40"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1192"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2013"/>
            <end position="2049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2451"/>
            <end position="2472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1434"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1616"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1197"/>
            <end position="1213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3222786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2616" mass="296160" checksum="4A492F50ACF0CAA6" modified="2024-05-29" version="1">MITTVTEANEYTETNDTNTELVASPNTMSKNLEKLTKKFTDVKFLVGINKKCVCGVKSILAANSTVFERMLFNGMKETFLDEIELPTYEYKSFESMIKFLISGRVDRHLFLTDQKFVLKVADLARCFDIPELLRFTEESFYKNLTLKNFADNYYLAEEYNFEDFKLKTLLFISKNALEFLNSEVFINLNKLKFVEEILNFIKDDVFAEDILNAIVKWINLNKGTNYYKKSKLTNLIQSLNFDEISNKELLILDKLGPLGASILNQTLRHRILYPVNPLNFRISELTWCEENSDIISSNSNQIFECRLANESLEFGTLTWEIEVIEACNGYWAGCAYSDIPKTTEVHLPQGAFVWGKHGQKMALLTLVADRIFLGVLSGSTNKRLPDYLKYDKGDVLKFILELGHQVEGRILKVCKKPAAGAKNQNEMFEIPFADLPLNRRFHRNGILYGDLEQKSSIGHTSTCPPVFITPSIFGYISGNSINFVETKYSTAVLTKPSDINQSQDLVSEIPSIVAKSQITAFAAFPAESLIAYAQKRSTLITILKWPQLTPVGVNKGTLQAPNDLEIVSLCFSNDGQYLASLGSLPHHSLCVWDWRGIVFHADHIGKTEVQLVNMEVSPLLCSTTNFGPATSISFNPLDKRMICTSNPGGGNARVGTYPNDEFDLEVEVGASDTFCKGIRFWKIIMGYKKWDIVPIAIKSEDSNTSKSNEKQLLPPTHSSSILNPYKENTEFSNPVVALGHVWRSDQSVVVATNKNFLMLFYPTKGTHRILEVERQFEYIEEKTKNSNPLMEFDINEDNSIGEAVALKTMKESQILSVRTLLYAKDIIIAAGTDGQINLIKTDKANPAVSKQLYLKSECETNNGILSLTFSPTFKNFLIEFEDGSLSMANTNFETFSVVSNTASTITCIDTCRLSSVCVAGCKDGNILVFDKDEFSVMETGEVEKGHVLAKTFKLPGSSITAIAMSPFASSLVAVGTKEGYLRLYNLNYRSDLTLFANSETNTEANVEQNVESNNVENETDKNLISDTNPSLLFIERLYSVPISKLIYDPTGKYLLAFADQGKAFVLDFTDKIKLSGFVEYSGKFQSAAFNLEGFEEEEKNNVIYLYILSSEEASGCSFIHRFILPISSSDIILENNSLQISKYSLLNSTYRIESLLVDIALLPTQLSSGRETFYVLSKERKLMTFIGPQQPGVSQKTSGGTATATVMSASSATSEKKESTEKTDAIIISKPLMEITQHEKGDCFLKKGYCIDWLITWSKDGNFVVKSLIEPDKEVRVLAHDPFCGGIKDLALTPIGDSIITLGNDGLLKFWRWRFTTGGKKTEADAILEWQRYIALKENVIRATHTILKTQKNIEDVIDSPNEQCLSNNNVSPRLVQEKVDLEKEQYTTSMNQKIAAIRERVAHFVLKNETLPSLEKIDKEEFVLDFQERDRLLAEADAKINNVKRNIESLNLKKVIIQKRIKKECWDSMKVIGQSVKSFNPDTLTGKIIEVTNYPIRILSSKEIKKANEIKMLRKIQVEVGKESNPKQKQTTKEADLLLDDDLISSDNTGSESKPDTLQVKEPTGIAALLYNPFDLITNERRRMQSILLNEYIYEQKTQFNNNFLNFATMKQDGISKIEEKNERIKSIMDELQRTSKEIEATDELEPKSSESTSMSKNELREKCTILRTRFLQKCGSTLSDDIKEKLNSKKLKLQNFRGSKVSPSNFNDCNFFFVERVKVAGQSGKFDCFIPGCKNNFTSCLLLRKHLNLEYHDLKAALEVLYDNDYLQSSKEARLNFEKLKPLEETHISLVIKDFRFFGENSFFNFNVTFENNVNTEVVDTVMEIAEENLSNVDNLCNDTSINFEDSAKDLRYFLTDNFGSALTPELISRMNSNEISITNFQSSKEISSQKDFFLNVERTRSKGEVGTKVTCPIPGCHVRLSSAVFIRKHLNTEVHSLTNIIDLISKAEAAKNLPLNKEREEKLNQLKNIDENQLKETPFSLKNFRFYLDDAFYNFNVTFGFTEQALIEKEPDEEDISAVNKESEVATEGDDSEQKKASRKRTTTTPMKVTGSKESFIYPIPLQDHLSIFEDGDENCETVYNGLRPSFENFLQLSEKEATDYLPPKITTHILNSQSDVEVDVFSSAKLALQQDSVFILNTGASVWGLDWVPGVKDPENQYLACAGHHSTLQHTSLGKRQFGADMKGCIQFWKINCLDENKNPELQLVILHDYGTVFDLKWMPYGGCEINQEEIMQNQDEMSRLGILAVAFGDGCFRIFNIPHISQLRQKLGITDLNEILYVEITTPLCEGRMADTLLWRLSWNGYQNLAVGCTNGCFSVWNIYDALMSKLKGKDFALNDIEPSVIFPAHDCSIRSVSCNDETKINRYLKDQKAADTAANFFTKPPSSSYHFISGGNDGNLYLHDIRDPYSPIRLQRIRGILYSCIFCPQFNGIVFSDDENQIRFLVRKNPKDEPKTEANSQTQKNEEQPDYDNLKAFKTSSLSCHKSVVWDMDCSKYIPFLCSGGADGFVNLSSMRRLNRRYEDKVMLFHLYQLKWIKEKNAFEYVEHKQPLFTSEAISQIKGSKSVLCLQFPEKVSIQKVCWNPNKCSSFWVASVGKSGLLRVENTLNPSKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZJ4</accession>
    <name>A0AAD5XZJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclear actin-protein involved in chromatin remodeling</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ARP5</name>
        <name evidence="4" type="ORF">HK099_001855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000157">
        <property type="protein sequence ID" value="KAJ3222838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZJ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="354"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="602" mass="70514" checksum="5D4C3E2C0932CEA7" modified="2024-05-29" version="1">MTNKLIVDYGSRYIRYNLPNSKEPLLLDNHSHQFEETMDLLLHPFTEAPSIMMTEPFCTPNHNRSVLNEMLFELYNIPRLSFGIDSLFSFDFNNNSKIDSGLVISSSFSSTHIIPVLNGTPMLLNARRLNWGLQDSIDYLTTQTRLKYPKINFSHHQAEKIMENFNKKNDNFYYSLDYFNDLKLIKENPMKYTFILQNPVKNTSINEISEKKRETGKLLQEMARERRIKKLEENKKELAALNKLLNLKLIDEYRFQNDLSKSGFKNENELLKIIKNMTEKIDLSTQKLFNPQAVEKKEEVVTKKYSALEIKELNEKREVLLEKIRVTKRLQLELKDKRSSASVKRMKSIALLSKDPNSNINENNSNAGMKRRRVTEKKKSKGEGGDDDFGLHDEDWAIYREIGNPDFEEEEEDYTLELEKIEAILKMEDVNFKPIIVDDRMVDSSNVVFKLAHSPNYDPESELTLNQMLFNIDRIRIPEIIFRPEIVGLDQMGLSELCQFILKNFEGDKKDLEKLTSNIFLTGSNFNYKYIEEKLIDSLKKNLHTDLNISVKTDMDFLNSGFRSMLNLSENENDAAFFTKEDYEEFGSSYFKESRFSNNYYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZM5</accession>
    <name>A0AAD5XZM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spermatogenesis associated protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SPATA5</name>
        <name evidence="5" type="ORF">HK099_005375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000414">
        <property type="protein sequence ID" value="KAJ3217689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZM5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000012">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="227"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="500"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="700" mass="78066" checksum="955B34CBDE3216F4" modified="2024-05-29" version="1">MEYSLDLNSKKVKKLQKKKKSNCTTKSVETEVNAFKISLQSVDSNLHNNFSIYVNGTDLKLLNLFHGDFVVFQNEDNSQLPLVKFSKEVKSLDLNSSFFVKTYPDAPSLNGHLPVLDDLNVQTFVKHYFRNLGYVLNQTIFEVSYFGKSVKLVASLHLDDQDFNLDCLYELNANINIKFVSTKNTRNKVKKKKLAFGGLVEEFRLCKEMVELALINPFKFQEFGLRPPRGILLYGPPGTGKTLIANVISEECNANLIKLSGPDILGKFYGESEEKLRAAFKDACINAPSIILIDEIDILCPKRENANHETQKRVVATLLTLMDGASDTSTQNQNFVILATTNRPEDLDDALRRPGRFDREIEIGIPNPSSRLQILQSHLNHIPNNLCSQDLESFSESMHGYVGADIASLAREAGLHAIKKFLEVHPGGDFRGSDLKLTSSDLKFGIKRVKPSALREIMLEVPKVFWEDIGGQHEVKQRLRETIEWPMKNPASFKKFNIKPPKGILLYGPPGCSKTLMAKALATESGLNFIAVKGPEDEIDALAITRGAGSDGGVSVNDRVLSQLLTELDGIDILLKVIVVAATNRPDVIDPALLRPGRIDRLLYVGPPDCDSIIEILKIKLRKMSCDVDVSAEKLASKLAGYSGAEIVSLCQEAGLVAMEEDNNALKISMKHFSLAIKRFTPRINKEMIRFYEEFSGKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZZ6</accession>
    <name>A0AAD5XZZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000262">
        <property type="protein sequence ID" value="KAJ3220941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZZ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase alpha subunit" evidence="1">
        <location>
            <begin position="194"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="726" mass="82746" checksum="6F769094D6EC656C" modified="2024-05-29" version="1">MLGLSVVISNALDNYDVMQIKLLHIDIMYLIDKESDAPPFIIHKAVRPRSRVDVAPKVVSIQLAKLDVNNLKYITWQAKNMNSSSSIFCPYHDECLGHLQSSDGKNIGLPPFCARADDPTEMSETDRLNKGLMNHSIHPRQYAISLRNCIAGKRGILKYKCMGFTPATSMRGVASCYWGEDYRTVMIPERWMSRIKVITRKEDQNLISPYYSIRNACKGDYAILSRSPVMSHNSTQCVRLLPWKHKSIGIHPEFCSPLNLDYDGDEVHICIIDGSSARHEAQLSMERNILDKFSSDTFKECLEDFWPNRQINMKLIADLMLPSTMSLTDVGYKSPSKKLHKLCRAKAELWNIVEFACNNRARRMKSFVRNSNTAIHELTESHIRVSEGFTVGRQLKHLLLQTTSNKNILNTLWFSNQPNNIDTMICNNIKDEEAGYPGTKLSSEISGKIQQALLDKAKHAISAPKRDLILSILTHQNGFSIVEYPDKTRKLVPEESYYRTDEKLLYSLSRSQLSREHDVRERFRRCIIAIDLGCKLNNIKATRRQVVEFAHCIWASTFNNHSDKMTDSSQIKFLAKTKSPSLLAAVCDDIYELDLRKGKRLYDTTMDSCNVMSAVMSIITDNTLNDAIIDDALSLFDIDMYIRLCRSRNDCATACGLPRNLSPPSTINLMQLLDDLLGIDLILFIVLCLAELEYIDRDMYSSNNILIVWPPYRFNLSSVARDVVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y099</accession>
    <name>A0AAD5Y099_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_003465</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000227">
        <property type="protein sequence ID" value="KAJ3221487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y099"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000117">
        <property type="entry name" value="Putative DNA repair helicase rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="370"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="542"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="754"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="764"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3221487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="789" mass="90593" checksum="374B191F020D1B50" modified="2024-05-29" version="1">MVKYSKQTNKQNGYSTNANNNKDTTTLNLEDQRIKEHKLFLPKISLIKEDSDVKLNSSNKNIIRDDVTDFFSTDYTFLPLKPDHKRRPLWVCHDGRIILEAFNQLAEQAQDFLITISEPVSRPTRMHEYKLTPYSLYAAVAVGMETQTIIDVLERFSKVKLPDEVTEFVKECTMSYGKVKLVLKHNRYFLESNYPEILRRLLQDDIIKQAYILPRENEDMAGVLSMDLIGNKTTSTAVKNGVKKIDEEDSFGAVITLDRLDEEEEDEDPKIISRKIAKLKAEDNEETDESDFTSSFEIDQKHLGQIREHCSNIDFPLMEEYDFRNDTTNATLDIDLSPKCIIRDYQEKSLSKMFGGGGGRARSGIIVLSVQQWANEFKTWSSVKGGQIAKFTAENKAKFDGDSGIVISTYTMIAHSGKRSYETEQMLSFINATEWGLMILDEVHVVPANVFRRVLTTVAAHTKLGLTATLVREDDKIQDLNFLIGPKLFEANWMDLAGKGHIAKVEATEIWCPMTGEFYHQYLASSAPKRRLLCVMNPAKFMACQFLIDWREKEGDKIIVFSDNVFALQHYAMVLNKPFLYGATTHEERSKVLDLFRKGDPKFRTIFLSKVGDTSLDLPEATCLIQISSQFGSRRQEAQRMGRILRAKRRNEEGFRSRFYTLVSRDTDEVAFSAKRKRFLIDQGYEFKIISNITELIPPNVIPTLKYSKSEDQIKLLNALVKENDSVCNEEELICSFDDIAGALQQQHFQNKNKKKGGFAGLTPEERQKRELKKEREKNRNPLFKAWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y132</accession>
    <name>A0AAD5Y132_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000155">
        <property type="protein sequence ID" value="KAJ3222871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y132"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041991018" evidence="1">
        <location>
            <begin position="17"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="419" mass="45996" checksum="98D6B9DCB89CDF03" modified="2024-05-29" version="1">MKTIFAFSLLVVSINAALNQANPRRGDARAPREVVETKFDEPGFYGKVTYKTTPGKSAVWLDNLEGLVNVDCSDSTQIVLSFEKNSQTALPEVWGSFPLNVIISSKYTNCLEKNSRVSSEIELGAKTITGTKDVKENTLILSVKPISFRKQLVQETQFEIYSKAVGSDAKLIDIGGNIPFFKDFSGMPLIDHSQLPGSVICSTCSLRYDLGWKIYGSLNLQGAKYGVTFTGTGKANFDLNYSLPKTYEFDSGVKTLFSYPIGTNVDIPGIVTAGFFVKLEGRLKVNTNGDVSITAGFDLVQREFTYNYDSQTQSSFSGGEIVPNSHPVDVKLEADISPSVHLNPVLEAKLKIFTKDLNIGLGLDNHFASNMHVSNSGICALDFKLDYTPSIFYRLNSIDNILKSFNTMVVVPKVCLKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y156</accession>
    <name>A0AAD5Y156_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005133</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y156"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="84"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="169"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="247"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="15"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="440"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="478"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="499" mass="52823" checksum="834ED7E212DEBC4E" modified="2024-05-29" version="1">MSDFSDMLAKAKAIAAKLSSQQSHSDPNSLKRPYSEDEPPSSGYRRDDKRTTADQLNSSNLPNQQSTSAYVLSQLQQLADEAKRGPIETFPISSKMVGLVIGKGGETMKKIERECGVKIQFSPDDVGPNRMVTLTGAEWGMKSARQQIETIAQNGINKLANGLGDVPHGAKLFEYHVPNNKVGLVIGRGGETIVNLQAKSGAKAVVTPDSLADANASTRVISLTGTDQQISEARKLIDQIITAGNMGGSAEQIFVPNEKVGLVIGKGGEGIKGIMSTCHVRIILDTEPGPMGRGMTISGQANDIETAKYMIDERLGAANSRSRSGSQFNSPYGAPEQPFNPYAAYPGQPPHSAGVEDPYAAAYGGYYQQGTEDPYAAQNAYYQQQAAPGQEAYTYDQSYYQNATSETEGAPGATADPNAAYGDPAQYAAWYQYYYGVAPPAGEGVPPGDGAPPGEGAPPGELPPGESDVEAAPTIPGTETENSNNENSQTTLPPSEKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1C0</accession>
    <name>A0AAD5Y1C0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Origin recognition complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ORC1</name>
        <name evidence="13" type="ORF">HK099_001207</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">ORC is composed of six subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ORC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000132">
        <property type="protein sequence ID" value="KAJ3223381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1C0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000199">
        <property type="entry name" value="Origin recognition complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF23">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="130"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="372" mass="42106" checksum="DF2EA16B4D6C58D4" modified="2024-05-29" version="1">MTRTTACKRSQNDDETNGAKRQKITVNVPRRSSNRITRLSTSKMLDDEQIVNAIVSSMGSKLSEKKVLSEKTKINSSANQQNICSKELLSDFELARTSLHVKTVPKHLPCRENEHFDLLRLIESNITSKEGSCIYISGVPGTGKTATVKHVIRELLETPAVKNFDFYEINGMKLSDPTSAFSNLSRMIFKKKFSISQSIDKLEKKFTNNKKNKHTVILVDELDLLVTKNQKVIYNFFDWPSRKNSNLTVIAIANTMDLPERVLLNRVASRLGLTRINFTPYDYNQLIRIVEARLEQIPNAFDADSILYCAKKVSAVSGDARKALDICRRAVEILQSKILQDESPTEVITFEIMQEAVKELFSTSALQFLMCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1V5</accession>
    <name>A0AAD5Y1V5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000096">
        <property type="protein sequence ID" value="KAJ3224341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1V5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052840">
        <property type="term" value="F:inositol diphosphate tetrakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020428">
        <property type="entry name" value="PFA-DSPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF48">
        <property type="entry name" value="INOSITOL PHOSPHATASE SIW14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01911">
        <property type="entry name" value="PFDSPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="115" mass="13234" checksum="494E70571D865460" modified="2024-05-29" version="1">MNNIDEENVEELNPMENFTMVANGIYRSAFPKKKNFSFLKKLGLKSILTLILEDYPELNQNFLKKNGITFFQFGVAGNKEPFCDIPETVICDALSVILDKRNHPSNNIFLMKKLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y239</accession>
    <name>A0AAD5Y239_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000116">
        <property type="protein sequence ID" value="KAJ3223810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y239"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041929430" evidence="1">
        <location>
            <begin position="19"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="536" mass="58929" checksum="EF21DEC8D7F81B6C" modified="2024-05-29" version="1">MKYTATSLVFFSLTLIQSAVIPAGEIGSQCGGFVGIPCNEGLECQVDDVHTADAFGTCVAKVTINGEIGSQCGGFAGFPCNEGLECQVDDKNTADAFGTCVVKVTINGEIGSQCGGFAGFPCNEGLECQVDDVHTADAFGTCVAKVNINGQLGSQCGGFAGFPCNEGLKCQVDDKHTADAFGTCVAIPKGAKGSQCGGFAGLKCNRGLKCVIADKGVADAFEYHSRKLSFYGQTNEQAEKLIQDGTAKKFCSNYDIILVADVNPDARFILKSIIEGNCFIKKLIFITTNRFDFNLFNEDKEMYYELVRKGHYPNKSGAEIIWVQNNPWEAKYCEIKLGGNYQDFTLIRPFGYSNLPEAEPISEEEAQLPAIHDHGFTKVFTKMVLDSGIKVRILPALYGGPSKVAQYKALLFFPYQTSTMKLYENLSQGVVTYVPTPRLLKEMIVIPGFDIDDHKHLANCINSGLKDWFNYIEVYNEDLSRFFYQFDTLEELKVLLSNPDVDPLNVRENGKRYYEEANAISLLKWSKVLGIKHNGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y313</accession>
    <name>A0AAD5Y313_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL35_1</name>
        <name evidence="4" type="ORF">HK099_004425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y313"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.310:FF:000002">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3450:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045059">
        <property type="entry name" value="Ribosomal_uL29_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="117" mass="13663" checksum="87A26E4C55B7B6BF" modified="2024-05-29" version="1" fragment="single">VKVKAHELRGRKKADLLKQLEDLKQELSTLRVTKVAGGAAGKVAKIHDVRKNVARVKTVLSQTTREQLRIYYKGKKYQPLDLRQKKTRAIRRRLTKHELGLKTLKQTKKDMHFPQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3L1</accession>
    <name>A0AAD5Y3L1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="1">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008307</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="1">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3L1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00068">
        <property type="entry name" value="CUZNDISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041905671" description="Superoxide dismutase [Cu-Zn]" evidence="2">
        <location>
            <begin position="25"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Superoxide dismutase copper/zinc binding" evidence="3">
        <location>
            <begin position="140"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="277" mass="30822" checksum="569BBC689E35B272" modified="2024-05-29" version="1">MKSSYIKILIVLSTIFNILPSISSIKTNSLQQNCSRKITKELSLIKNLDVRNETIRNNFNVNLKNVKLPSSISNLSLMAEDQEHFVVTLLNEKVCLLSFNYANSSNEFNLFNMDSGEKKIAAVNLLPDVSFFNSSVYSIEGEIKFKQEYGKTVEISVNISGLKPNSIHGWHIHEFFIPVDEALLNCTKGGGHFNPTSKMHGAPFSSNHHIGDLGNIKSDRKGRIRIKRYHDAISLFNDTEASILGHALVIHESKDDFVTQPTGNSGGRLGCGNIVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSW3</accession>
    <name>A0AAD5TSW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001872">
        <property type="protein sequence ID" value="KAJ3200594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="Toastrack_DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4097" evidence="1">
        <location>
            <begin position="173"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="387" mass="42891" checksum="46F5E368BB407207" modified="2024-05-29" version="1">MNTTHHSSENVKDFTISVNGTASGTLFLNHTADSNNITIKVDYSNYDENLRTQVKVKEVSGDHYKFEMETPPFASFGGFFGSNVVGKNSIIIVAHVPNKDYENVKLSTHNMAIEMDNNEKYPLSVNNLTMETHNGKVNFMGVDAKNSLKITAKNGATHFGNIKSKIFEFVGHNGHFGIQNSTFSENLYLSNSNGALKLSQIFSPLSKIDTHNGHVEINEAKFNESNIFSKNGRIILSNSTIANSKLETHNGKLVLEKNIFENLKAQSHNGGVTGSIEVKDSLVVDTDNGEICFKPLRLVEKVEKCQISISSSNGRSDIDLENFNGRFELYGGSNSSIYGRDVFINASEEQHKRRHTIKTGEVKNTLFNENQTFKISAKNGGIKINNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTN4</accession>
    <name>A0AAD5TTN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001714">
        <property type="protein sequence ID" value="KAJ3201519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTN4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="94" mass="10354" checksum="8BEBAB112B73DA8F" modified="2024-05-29" version="1" fragment="single">MQKNSIKISKRGIKVYYFDEDKDLILINNDKDLEEAIVTCKNLNLDKINLKVENIGEDDSGSNDSNSTNVSGKKLLGLENNDINLVLGGTGLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUK7</accession>
    <name>A0AAD5TUK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">40S ribosomal protein S9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RPS9_1</name>
        <name evidence="11" type="ORF">HK099_003409</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002230">
        <property type="protein sequence ID" value="KAJ3198918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUK7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000021">
        <property type="entry name" value="40S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_uS4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005710">
        <property type="entry name" value="Ribosomal_uS4_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003139">
        <property type="entry name" value="PRK04051.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01018">
        <property type="entry name" value="uS4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF5">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="10">
        <location>
            <begin position="4"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="9">
        <location>
            <begin position="105"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3198918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="21861" checksum="F5CD455ABC8A75AA" modified="2024-05-29" version="1">MPRTNCSKTYKVPRRPYIAERLDQELKLAGEYGLRNKREIYRIGYALSNIRRAARELLTLEEKNPRRLFEGNALIRRLIRIGVLDETKAKLDYVLGLKQEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVGRQIVDIPSFVVRLDSQKHIDFALTSPYGGGRPGRCKRKRAKSAAKDGAEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUW2</accession>
    <name>A0AAD5TUW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium-binding protein NCS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000870</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001218">
        <property type="protein sequence ID" value="KAJ3205282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUW2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000009">
        <property type="entry name" value="Visinin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3205282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="190" mass="22169" checksum="929F5B0B21DE8320" modified="2024-05-29" version="1">MGSAKSKLLPETIIKMQKSTYFEKKEIIQWHKSFYKDFHLGHISKSEFQQSYKQFFPFGDSSSYSDLVFNAFDKNNDDLLDFEEFLTALSVSSRGSLEEKIKFCFEFYDLNKDGFIEREEMAAVVKAVYLLIGNTSEIPEDESTPEKRVEKLFNFMDLDKDDKLTYEEFKLGSEKDPSICHAMNLYQGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV52</accession>
    <name>A0AAD5TV52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001705">
        <property type="protein sequence ID" value="KAJ3201581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV52"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="23345" checksum="CB8693D6D472DD09" modified="2024-05-29" version="1" fragment="single">ALENIHYQESIEIANYNKVRAVEREIKRRQEIKPLPMGNITDSRTIPPHHLSLRQHTKDEVLEQIALKKKLKYEEKSRQLFEDKFLNNKFIQQFKSNEEKEHRQKLEKKQQLREVLHIQVQEKNSVKEAEIKMENKFANDETQYFKNCRERARKLYQEQLQLLQQKKEYEKQVLELQKNSQIERLATYKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV78</accession>
    <name>A0AAD5TV78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Delta(12)-fatty-acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FAD2</name>
        <name evidence="3" type="ORF">HK099_000529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001120">
        <property type="protein sequence ID" value="KAJ3206495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV78"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="68"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3206495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="365" mass="42287" checksum="66FFB57DD43B4EDF" modified="2024-05-29" version="1">MPDKVQPNQKQPFTFKQLQNSIPKHCFQRNLLTSFSYVFVDLLLASLLFYFATFIQHSKLQIFYLPLYWISQGVVCTGIWVLAHECGHQAFSDYGWVNDTVGFILHSALLVPYFAWKRTHANHHKKCAHMDYDQVFVPKTRSQMNLPDGEDLALSVPIVSLLESIKMLLLGWPAYLLFNISSQQYDQWVSHFIPSAPIFEKSDYNDIVKSNIGVLFTISILVYLSNIFSFLDVAKYYIVPYLVVNGFLVLITFLQHTHPDIPHYRGEEWSFLAGALATVDRDYGILNYFFHHIGNTHVAHHLFSKMPHYHAQEATEAIKKVLGSYYKFDNKGIFQALIDTMNECRYVEDTGDIVYYVNLKEKKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW42</accession>
    <name>A0AAD5TW42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001515">
        <property type="protein sequence ID" value="KAJ3202847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW42"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052811">
        <property type="entry name" value="Glucose_resp_signaling"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263">
        <property type="entry name" value="ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47263:SF1">
        <property type="entry name" value="C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="462" mass="53407" checksum="05931F3222F62564" modified="2024-05-29" version="1" fragment="single">MVPSENNGGGDEVTNNFVFIPSKGFITIQIDHARNLKAKDKNILSSNSYCLISLKNKVEFKSKTFPSNLNPFLNFSICIPISFLLESNFQISMWNETLLEREDDSFLGLVTVSYETILQLNKKPFDNWQKLEKRSPRSNVSGEIKVSIKYSELNNDYQTIPQNPEISFEHILKKLVESVTPIKNENDNNLFDNAMLTLDDLSSSWRTENLKLILNCLFSKSEISLLEETAVTLFEAISNYLKHFFERDSMILDLPKEIEALNDEPKYDGVVSYGQKSLDAAIYILQYLFSNSIFKNVFITENAKSVDIAGMVKELLQDSIVERFKIINTKASSNNASNHPLTLEKLSKLMLRDIKVIKDVFNELILDFVHLPSMMSSFYFNIIQFELEKFELVSFHSENDLSSMFALYTNVNILKNLIETIDFRISNKFRMDFWFFPFIKKWLGLTETKLLEWVNSAIKIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW56</accession>
    <name>A0AAD5TW56_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial phosphate carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_008272</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000897">
        <property type="protein sequence ID" value="KAJ3210317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW56"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF12">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3210317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="29937" checksum="31941E01C94708B0" modified="2024-05-29" version="1" fragment="single">LSHVGICCGITHGALTPVDVVKTRIQLDSKSYNQGMIGGFKQIIAREGFNGLLTGFGPTAVGYFIQGWFKFGGVEYFKVTTSQYLGTKKAWEYRFSIYLASAAAAEFIADLFLCPLEATRIRLVSKPSYASGLISAFPKIIKEEGTTAEKIYFTLGKNPDQMTSNQNFLISVFSGIFAGIAADYNYKKISAIVSHPADTLLSLINKSSTAGGSGSTTTRLLNLAKEVGFKKLCLTGLGARCVMVGALTASQFGIFDLAITTLGTEKYHFIDPNKKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWM9</accession>
    <name>A0AAD5TWM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001477">
        <property type="protein sequence ID" value="KAJ3203098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWM9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="262" mass="30379" checksum="ADE1F1E750DF330E" modified="2024-05-29" version="1" fragment="single">SQNSINDINDFTSKNFHNQKSFASNFLATKSLTLISTLKTEPSFNTIDKFFCSFPNLISLKFVSSSLLTKYGLNLNQLNDLFKCCTNLKRLELDYLYIDQEQYFDLPFLKNFESLKELKVKVVKGTICNIATFFNLYPMKALSKLELTNPSNETLVSMTKSLQNLESFKVFDYQANLKEWGLIQFLKNNINLKHLHLNFLNSVKIDMDVILYKICEFNLNLNSVSIIGARKISFDGLNYFFNKFSNKLKFIQLNYLGLTLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWP2</accession>
    <name>A0AAD5TWP2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000797">
        <property type="protein sequence ID" value="KAJ3212070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWP2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="222" mass="26066" checksum="706E6F128F373301" modified="2024-05-29" version="1" fragment="single">ENFQKEMSNKTFFDLRNVSCSSCKQRVSPCVDELEQSMTNHFSPHLHAHYSDSFKSCFCETSEQRRVFSKCITDYKVNVPSSSSSSCKVFHNFPSAYQLPTLCESNPIPKEFFLDYYNQYYQKNSINTIQTHSEFQFWPLIFLLLSLTTFIMIALFIRKKCVEGDALEDFNTNIPLEDRNLYHYHQEFGDEQLPKYEGREIITLPDKSYKIGNEVESNEIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXA4</accession>
    <name>A0AAD5TXA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta-galactosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000406</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001097">
        <property type="protein sequence ID" value="KAJ3206819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXA4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048913">
        <property type="entry name" value="BetaGal_gal-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21467">
        <property type="entry name" value="BetaGal_gal-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase 35 catalytic" evidence="5">
        <location>
            <begin position="4"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 35 catalytic" evidence="5">
        <location>
            <begin position="184"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase galactose-binding" evidence="6">
        <location>
            <begin position="804"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3206819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="928" mass="106127" checksum="6F6FD2A05824C774" modified="2024-05-29" version="1">MAAPGPYICAETQGGGFPMWLLAKKDVRIRHSSSTFFKKYDQNFSKYCLQWYANILPILKKHQITEKKNGCVIALQIENEMFEQLFKYLPIGLSDEMRHLCEAARNFRMTVPFFTNDAFEEGSFNPKSSKFGIDLYGFDKYVIFVPISSPLGALLGDSTKQTAGRIEFADWEPKTFSAAVDIMEKKVRSFKGGAAESPIFIPELQGGWFNHYTVPYTYDDIYNFYGDNYTNTLVNSVIAQGSTMFSIYMFYGGTNWGTLGDPDVYTSYDYSACIREFGYLSGKARRLRLAFCFIKSFSNLISQTDLVVGNAEKDWTLSVSPPQILNRIRKTAMSNNATEFVFLRNFSSEKRSKVNFTLKFATKSIKMNCNLPYKQSFIALCNYAFCDNRFHLLLNTAPIHMRIKQDDNTEIWMIQNDEECSGEFAFRGEVKVEGSLKAEIRNFHISDDNYSIVAFNKGAGWASLSNGVDSAKLLIFSLNSEDLLTFYAKFEESWFSKTKITQPHSAFTNPTFCCWGVDGAKLYDGKLSIEATKDQQYIFSLNNSCPQGFQEIDKLGEVEDDNITKYLGAPYLYIYSLVKETSPKQFFEFKRPALTNWHFRHTSFQSLPWVPLKNLASTNYEFKPSMDPLDFGFTSGHVLYKFTFDINNKATTIEFNISYRHRATIYLNGEAVGGSLTYSLQLFQPGTKVGPEWNFGGWKRFTLPKNILNETNELVIITESFGLNRQAFIFNDCRNPRGILGLKFSKGSLKNLKSFISGVDIKNVIDSFSSSGFPDENISQWNIVDTVKNKSTAIELELKCNQLPTWFKGDFQYTRTHLHIPLRLQMGGRGTAYIWVNGFLIARYYGNGDSPQKNFYIMHGILLEGTNEVKLLCYDGRVENKDNSNENIFVEIKEWKVNDSKVNLNDRWSGNIEENGKSYVVFRKDLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXR2</accession>
    <name>A0AAD5TXR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006506</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000566">
        <property type="protein sequence ID" value="KAJ3215129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXR2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051530">
        <property type="entry name" value="mGluR/GABA-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46924">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR-LIKE PROTEIN C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042070363" description="G-protein coupled receptors family 3 profile domain-containing protein" evidence="7">
        <location>
            <begin position="19"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="544"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="592"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="626"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="656"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="8">
        <location>
            <begin position="434"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="693"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="700"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="710"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="736" mass="82060" checksum="37113EC007D9CAC9" modified="2024-05-29" version="1">MKINHALVLLIMIMLIEARVKLLLLPFTKNTTLELEACQPTIDKIKSETGIDVIVEFAGTSISNDYLSFVSSLLTFKDVEYDILSLDIIWPGQFSEHFVDLTNKIPKELLDLHLQAIVENDNVNQKQIAVPLFVDYGVLFYRTDLLQKYNYTSPPQTWDEMHNMLATILPKERASTNPDLYGFSGNYLGYEGLTCTFVQWLYSIRSSVVSSEIIALDKTVKIVSEEAIKLLDMFSKWITRDSFTPIASLLWNKADLTNKWLQGNLVFMLNWPAAAGATRGSPLKTSFGVSPLPGSVPGKSGAALGGYQLAVSKYSKNIDDSVKVLRYFLSPEFQKERAIKVGYLPSVKNLYFDKDVCNALGYCDVYQNLQVVARPSSQTSPRYLQVSANIFGWVNKILGGTVSAEAGLRNMTVDIQKSMNTFRLPSASVPVEILYSGIALASIGILVTILFAAAMFKLQKHEVFVAASPLFLSFYLFGALLAFVGLLVFNLNLKVASSCNATLWLFSIGCLTLFTAMVIKNWRIQKVFQTSSKLKVGSVTPVKMVIYIGSWVAVNVIILLCFLFSNGGYQMMDVEVNSHIWNICGMQNQTTWLFILMCPICLTLLFGIFISFGTRNVWSKFNESKHIMMAIYTFTLSIIILIPLVLTSSLPSTQHLLINLVANCSLLLVISINFLPKLLVVYSKTPLNEGPMETGIKKSTAGSSVVNSQRGDERNSQEKQAEYCTHCQHCIANQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXX7</accession>
    <name>A0AAD5TXX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000510">
        <property type="protein sequence ID" value="KAJ3215921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXX7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="271" mass="31856" checksum="1BC57F635A979DFE" modified="2024-05-29" version="1">MLATNNDEIENLEWSWIQINKKNSQCSSERSESPAESLNSTFLEDIEWTFIKENFLKKQHQHNNSCSFLNNSNSFDQAISYSAQEFSFSRPIGQQNQQQPNFSTHTQSNVLGLVINRSNLVQEKQQRSRQNVIVSSDVNYNPEMKRSLSVSSNNQERKKFLIEFNNHYRKEDKKKNEVKVEEEKNDPFIVKKSKKIIKELKKFVKNHFNFSADESGGKEKEGEETGCKENMLHKEIKEFVCFWLKNFGLSFFFSYIFVKIGTFFHDELLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY37</accession>
    <name>A0AAD5TY37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">E3 ubiquitin-protein ligase Zswim2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ZSWIM2</name>
        <name evidence="8" type="ORF">HK099_006549</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000572">
        <property type="protein sequence ID" value="KAJ3215059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY37"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16494">
        <property type="entry name" value="RING-CH-C4HC3_ZSWM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039903">
        <property type="entry name" value="Zswim2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540:SF3">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZSWIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540">
        <property type="entry name" value="RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="7">
        <location>
            <begin position="172"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="267"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="6">
        <location>
            <begin position="353"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="472"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3215059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="712" mass="81338" checksum="E664A679241CA3A5" modified="2024-05-29" version="1">MKVIFGGILLLAIFLVSIIPLLRKIWLNKVYVGRLEEEVTRELDVLHSNSLDLEPLPAYKKSPSTMVAEMTEISGSNESSNSILPLHSRQSTLSNLNIPQLSPANSVHSLSDPPRYQNEDALSQKFLIVQTMGPMAFLLKPHTQIDETETKEQIQGIHCESNKLKKKNPNLFRICLGSLQSCSCSTFMNERELCVHILWVMLKVYRVDRSDEKLFQLSLVEREITELISQRNKSKLKSANKQNEVQLKNCSTEDGVVRRDIEEGDVCPICQDDLIGEQPTIYCKKSCGNNMHSKCLKVLMEHQVRTLGENLVKCPLCRKDFGTCEEINQLIAESQPTRSKQILLKKKLNLKKHFGFKCMNCEINPIVGKCHKCLICPSTYLCEICFMQGHHSEHSFEHRLEKHSSWEPSIRVVDTVFPQAMLDQLQGRELTDLDYEKLLLLDQKSTQGNIPLHVINSFPTEKIKDPRKREECTICAVKYVFGSLTRKIPCGHSFHQSCIDRWLLQTRSNCPTCGENAYFTLNQKNGQEDEKINLDALEYIASPVKYEAIEKKKKKKIKIKKDTKSLEKVDTNLIEIVGKNNSNYLNVHLEKKPVSFIRKKLETKIQGRNLKLIKLKPIEKNRELNFTELSIVNLKNNSNHITGVNLVVDAKDIILKHQSTSEISNKNFNNSVLSKSCKKVLPKIQFAKKNNAELNVVESFELLGKNFNLSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY83</accession>
    <name>A0AAD5TY83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000515">
        <property type="protein sequence ID" value="KAJ3215865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY83"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="451" mass="52561" checksum="22164172A813A4F1" modified="2024-05-29" version="1" fragment="single">MELGQLDILNEKFLIATADEEDNLAMKYLNHVQSLLEKEVVKPDSIVEKITQNLKENNQMLQIIGWSIVKLFINRTMYDGVSTFFQLVTLNSNFKELSLFSAEFINESVIAAVDLDFRIDEFIDKLSFDYIEYSRILVLTTVKIETNKFSLHFDHILETLNKGFEISSKINFEKFGKLTVVPKVNENPKLMKKDDEIVKVSKDVIKNRAFMIQSMYMIHELGIDILQLLDDDFNRNDELPNVGITVFLSVLFAYLNSPSKKRFKNSKKVKFSHILQSTTNHIFWKSEEEEENNDSQFFSLLIDFKILFFKIFENRIEALFKLGIENDNEYLIDIGLSAVEYFMNRIGENDIDQDLIIKYDTKKILNELICYTGLIKSSLQREKLFLLIQKFFFGFKSNCFEVILKDLIFSGFEYNSNEAQLEINSSHLAIFNVVGISLLKEVCVKEFAKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYD1</accession>
    <name>A0AAD5TYD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000543">
        <property type="protein sequence ID" value="KAJ3215439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYD1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd13437">
        <property type="entry name" value="SPFH_alloslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="79"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="318" mass="35197" checksum="05BF2DE883FFAE53" modified="2024-05-29" version="1">MDPNYSQEQRTTDPYPQPVSRNIINTQPQQTSPMNTQKLFYHEIPIGKSEHGCYEGCLSFFGKIFGLCGATPCGCCCPNPYKTVSQGEVGLITKFGKYYKSVDPGLYQINIFTEVVQKVNIKIRIEDIPRQTITTKDNVSCSIDSVLYWNIVDPYTATFLVENVRMAMNERTQTTLRTIFGTKTLQECIEHRDGIAAEISELIAEPAAAWGVRIESILIKDLQFSQDLQENLSSAAKAKRIGESKVIAAKAEVDSAKLMREAADILNSPAAMQIRYLETLAGMAKTSGAKVIFMPASNSDPNSGLGNIAQQVYTQEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYD2</accession>
    <name>A0AAD5TYD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005753</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000463">
        <property type="protein sequence ID" value="KAJ3216722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYD2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF165">
        <property type="entry name" value="DECARBOXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G04980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="522" mass="57628" checksum="5C79437C49358AA8" modified="2024-05-29" version="1">MENLVWNFKKEFSTHLVNGTQVVKSKLSIENAILSVSGSSLNEFTVDDENSEVKTLLHIINDIVPSLPNNNGSKYFGFVTGGSTPIAEAADNLVSFLDQNAAYTSVFLRQNVIGEVENQSLVMLCEMLGLNEEDWRGRTVTTGATSSNVLGLACGRDYVLGNGGAAQNGVSSDSTIKIISCGSHSSIQKAAGITGIGRNNIIEKGLFRKNDDLGVNLDLEELNSWTNTKDNNVKAIVVVSFGEVNTGAFTKDVLKIRKWCDDNNAWLHIDGAFGVFASLHPSLKNIVRDLHLADSITGDCHKWLNVPYDCGFFLTKTKHLPILLNVCSSGSAPYLGTTDNQSIFEPYQISIENSQRFRSLPLYASLKAYGIEGYRKLVTRNIEFARKLENWLRSSHYYRVLTPLYNTESEFQLINIVLFTIDNAAPIMTESGSLKDAVALIHKKILDTGLMQLTTTVFNSIPGFRIAGIKIEIKLFLLKSLVSNWMTGLSSNDLKNKKNMNCCEESDEDFTTVISVLTKVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYQ1</accession>
    <name>A0AAD5TYQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional regulatory protein sin3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SIN3</name>
        <name evidence="10" type="ORF">HK099_007627</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000757">
        <property type="protein sequence ID" value="KAJ3212958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="9">
        <location>
            <begin position="605"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="195"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="291"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="404"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="453"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="455"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3212958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1360" mass="155787" checksum="5FC0C0961E22B449" modified="2024-05-29" version="1">MNVTSLSNQSDAEKNHVRSNKQNAANLTALQQQPSQNSSLSTAQVAISLTQSLPNTSTQDQSETTTYRQLNVRDALTYLDQVKIQFEAQSEVYSRFLDIMKDFKSQSIDTPAVIERVSTLFRGHSHLITGFNTFLPPGYRVEATNNPLDPIIVTTPNDQVGHAPNYRENSATIISSSTQNYTTEVVPTRFKEPTYQSVTQSGNPPFSSHNLSLHNPNLNVSLPPMLSANEKQPASTPILPSFSHSHSPPVTINTPSLPQLNNSERLPPLPGVPYISHVPQPVIPQIHQHNSFSTNTQQSHQQLPLPTLPPPQVNQQQPPAPTPLPPQPPVAPVNAAATRAKPNVEFNHAINYVNKIKTRFAPQPDIYKQFLEILQTYKQSKPIQEVYAEVENLFQGAPDLLDEFKQFLPDPNSNNNSNRPTPNAPASTGHSGGLRSNGMEVLVYNTEEILGSPTNVNRSFNKRSNNSGSGNLSASGSYNFTTQSAQPTQPPKKKTKSSQKSANLNSNINQSVKLEELDATKMEELDFFDKVKKAINYKQTYNEFLKVLNLFSQEIIDSKTLIERVFPYLEKSPDLFDWFKKFVKYEEEDVVVNEVAVMPRADPGQFKLKGKSYRLLPKDFARGTCSGRDERCAEVLNDDWMSHPLFTSENGHFSTSKKNAYEEALHKCEEERYDFDLNIEANLHAISIFEPIELKLSEMSVEERNNLKYPNGLCEGASKAIYQRVIKKIYDKDRGLEVIEALHQNPAVAVPVVLKRLKQKDEEWKRSQREWNKVWLEIDALNFVKSLDYQGENFKSFDKKTLSSKTLLSEIEQLYKEQKEKMSSNSESDLLANNCPKYQYDFHFKDQELFRNCRELIVRSLEVISSNNNENGNGNNLNLGIEKENLNKFLRDFFGKFFWNYFEEFGEDEIEDFEFREDLIDTNNDEEDSEDCTMEDINNNYYGTDTEDDHSSKNFSIKKKKGRNLRRKMMIKRVKENRDSSRAKKNLQDSVISNASSSVAPQRSSYTFYANSQIFVFFRQFQILYSRLYKIMELSKELAENPPKVKELNNIAVNLGLQKESDIVFKEEERFPNFIVNLYELLEGTMDSSEFEERSRAMFSTSAYLTFTLDKLSNLVAKTTMNLLNDQTSLKLFDMFYEERLIRSTSSHQEQIYRSNVESCLGDDNLFRIEYFVAEKVATVQLLCKDDKVYDESISSEEKWSVYVDHFVQLGTISDQSYLYNNKNQSAENSSYQGYGNPPFSLSLKKKKTPFLKRNLPKLISDDPPINVQTKSGLELKICVNTYKIFFVDNTEDYFCRLHNKATNEGKNTSEQEKKKKIKVSQWLENKCWSGIDEIEKEKLKKNFTEKFAISTKNTDIDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ63</accession>
    <name>A0AAD5TZ63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_008104</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000858">
        <property type="protein sequence ID" value="KAJ3211054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ63"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000388">
        <property type="entry name" value="Putative RING zinc finger domain superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977">
        <property type="entry name" value="TARGET OF ERK KINASE MPK-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="420"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3211054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="467" mass="52729" checksum="16972A70A7D8A5F9" modified="2024-05-29" version="1">MALKATLFSSLNNNSSTQIITTISVSPLYLTIGDAQLGTLIDIKDNCVITKNNFFTNVVNTTTTYLNSYIPLIDISAFPSNNENCNINILLNSISTLNLSIPILLFYNINPEFSIENSSFDMYGVTKSIADEIKLKMSSNFTVTAAFKSLKEPIIKSFSLFQFVMIIAGILLCLALCSSFTLHFALFLRKRSFRRQQELHVPTQSSIPVVSKRKTLTSDVIEQFPKSLYTKTKLKSDKLEINYAKFENDAVLSTKAKTDTVINKVSTDESDLFGDKQNFNLPKFSSINLSDMYNKELTLRRKVVLGNSIEMKNIISTDPEESEKSQKNNPDETAIYIPSDFMAGSCNSVETILTIRSDCETLQDFSLETESKNKTSVEEGRDFQRRGTEDTITFETEGSNTSHVSLISFTSSKNELQETCVICIEEYEESDEIRTLPCKHFFHTHCIDEWLRTKSTQCPLCKSDFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZH9</accession>
    <name>A0AAD5TZH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclic pyranopterin monophosphate synthase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CNX3</name>
        <name evidence="4" type="ORF">HK099_005006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000373">
        <property type="protein sequence ID" value="KAJ3218579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="entry name" value="Molybdopterin cofactor biosynthesis C (MoaC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="MoaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006870">
        <property type="entry name" value="PRK09364.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="Molybdenum cofactor biosynthesis protein C, MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin cofactor biosynthesis C (MoaC)" evidence="3">
        <location>
            <begin position="27"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="189" mass="20867" checksum="A34E9539678DBC7C" modified="2024-05-29" version="1">MLLSPPLNRKFHNIGLTHVDETGKVKMVNINEKLATKRTSIASSKVYFSSNESFKLLLENKIKKGLLHVSGDVLTVSKIAGICAGKLTFQLIPLCHQVNLSSIDINFRFFPEKNYLSVFGHCETGESKTGVEVEAMVAVSVASLTIFDMCKAVDKKIIIGDLKVLHKSGGKSGDYSLNQELEEYYLGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZM7</accession>
    <name>A0AAD5TZM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001038">
        <property type="protein sequence ID" value="KAJ3207691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZM7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="265" mass="29913" checksum="652CE0BE42365F84" modified="2024-05-29" version="1" fragment="single">MSTTKNLNFFKLPFEVVEMIAKDLDWKSFLSLQNSTKTMKGSEIKLTNKQILEIISLDVFLQANADGSVFLSELQKTYIKQLKMTEKTLPKLLASSFIPIAVNCHELEFLRFLMLNGTHFNFNELAELARIQNDLDAIELLHRYSTKAENETSTVGSETTTADNEATPLFYTYGADPKVLEYNLLATCEETQLEVNWGAIFLCAVNNGNHELIKILLRNELVDPAKDDNYAVKLAFENSDFATVKLLLSQIKVSSSLNAEELQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZP2</accession>
    <name>A0AAD5TZP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005174</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000393">
        <property type="protein sequence ID" value="KAJ3218160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZP2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="5">
        <location>
            <begin position="28"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="374" mass="42015" checksum="9162E891575FC4AC" modified="2024-05-29" version="1">MKKLSKIDQNLIINANSKSKLIKHNNDIYTLHSNYLKSNNPIEDNRSENYSSDKFMLGVFDGHGGWECASVLSNYLNAYVSKELRLIKNKKSSNKKEDIINAIKTGFNKLDADILKGGFENKNYLEPALSGSCAVLLLMDGHDVYVANTGDCRAVLGKQNEDGMFEAVPLSVDQGVDNLNEVKRLEEEHPGLMPSRAFGDAVTAEPVVTHYKITPPKITVNKKDQKVLLSGDLFLILASDGLWDDLSNEESVKIMQNYLHSNKFIDTFDEKIEKNFVFEDLNASTLLIKNSLHKNSKGDIGKLLSIPYPKCRNYRDDVTVEVLFFFNTNEFLGVGEEGKVTFDKDTKEADLKLANKKIDRINISNFISGMKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZU7</accession>
    <name>A0AAD5TZU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_004999</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000372">
        <property type="protein sequence ID" value="KAJ3218617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZU7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="568"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="624"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="664"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="712"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="750"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="777"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="repeat" description="Filamin" evidence="8">
        <location>
            <begin position="420"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="10">
        <location>
            <begin position="523"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="619"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="527"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3218617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="951" mass="105963" checksum="29AA7FD9B1DDD669" modified="2024-05-29" version="1">MRNILIPVAIIFSLISTRITTINVTISFLFARPSPNDTVQPDDVECGVQIGYEIGMRRIQELLDPFNVTVNKAYRYAGTNLQTMQHAIDLSENVPNLIASIGQKLTSLCVEQAVYFSSLPRPVISISPSSGGPKLDKKQNYPYFFRTLATNRVEMKALSAFISNYWKNIGVLYVEDIYPISNIEPPLIVQESFAIDSKADQTAQIRTGLTKIKDSGVKVIFLGVFDYKIVYEGAVELGMINDEFIFIGTNIYQKNNDSFFGLIFDNIYFETENPTPEYLYLEEAWTRQVSNDPTSVFYDSRPPPAQKPNIYGMASYDAVIGLGHAMVHALQNNVSVLDTVTLAEYLRNLTYTGSLMYQKGFNEDQDGKADFSMFQDVGIDQPFNLIGRYNITSNHFQVNEGVPIYFGNSPNASLTPPSDGSNPSTKNTVALGIGLTQAAAGKRNIIDLKIKNSFRNRVAVNETEITLELSKENNKIDLQYNVTFTGVTGEFEVGYNVPTYGTYLLSIFLQGNHIKDSPFVINGIIECNPQCDRTGLCQSDGTCACEAGYTGKNCGELFPLTTFGITTVTGIIVLAFGALNVVLVIGSLTLIYIFRNEKVIRVASLNFIMTIGGVLSFTTTIPCWIAPICFHVGFTISFITLLIKNLRIVMVYSGNLKKSTMRSAPLYISGIVSLVAVVIIISQLTHPSTVVIVNYSNSRILECTDSLNPWQILLYAVEVIILLSNAFISFKSRQIADIYSESKTIAISTYTVFMLILVYYFMIHNGFMYIIKFNASVLVHIAAPMISTLTILTWKIYGVYFVVATAHIKKSSCDDSILSNSAVNNAEVVTGLKVEGGFEFEFKGKKLGISGLFRPNLHKIVVKVLVSRKIVTFIHEDSRYCWSINLNACKKEKFWQVVYDENEEIKGVIITGAESSFWLQGNPILIEELRNILYQMFNKTGSSIQKTKTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U029</accession>
    <name>A0AAD5U029_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000581">
        <property type="protein sequence ID" value="KAJ3214925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U029"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="798" mass="91994" checksum="D2B72EA2298781E2" modified="2024-05-29" version="1">MGNVFTKNKKKKKVNQKTSDIPQNKLQVENKYTFNDVIATRPVSNLYTYAPKRFSSAQTNLVSISNDTHRKELSKHEKHPLNIDTRVNVIAQYQLQNNDLVESPSTCGSENFPFHADFTACNNLPPPLSIWNGDQLDLNISTDGARYQINQVKAFSLPVSSLDVYQRFDVKNTGHINSDDNRKSLQMNAVMEYNSNSYFPINNQLQNSMDSTISKNCLEKKEDKSSVAIRNNLNRSHSFKKAELLKFLKKNHNSNSINYEEEINKRMSSSQCFYESISEKEMPKMQNESVEKKNDTIIKTEIKKFVPVQSKQYSVPQSHIRPQVQCNPDYRLSHPLPQSRPNPSSANYSHRFSQPAISLQAVKTALALNNMHHRLSHSTPGRSRPVNPHHDSLKNNRLSHTHFQNLQQLEPNSFYNPKKSMELDLRQIYFEEDDKEKSVKKLRVTNAVDKELEEEDDDDDAKGRNFSTVVVDDLKTHLQPNQNFSESEAKDCYSKKKTLEEKNLVGDIVIQRIDSADKVEDQSNITLIEESLIDQNVNNEIEKQASRDVAVYDAPINDVSPDRTSNTFLQNFLDEKGNSRNKSKFKVKYEDRWSVLYGNEKVKVQKSFENLEKNKDLNLNNNESIFIGPRGSSLVEMQKKLDRNYNFSTENNIIISQRFNSLLNPDARYSSLMNPEPCILNSVQEVDDDIKSSTTESLEKYKHFLSLKKTRTKYSNYSLNSNGETETSSQLILKIYGGNRDETLKRIQTLKSNTLNSNTELETDLNATRLEFLEKEKKTSNILNFETFKKELEIFNME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U061</accession>
    <name>A0AAD5U061_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004803</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000350">
        <property type="protein sequence ID" value="KAJ3219172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U061"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045492">
        <property type="term" value="P:xylan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006514">
        <property type="entry name" value="IRX15/GXM/AGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31444">
        <property type="entry name" value="OS11G0490100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21729">
        <property type="entry name" value="IRX15_IRX15L_GXM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="460" mass="53081" checksum="5E318417EC055A76" modified="2024-05-29" version="1">MNKMFLSNNLPYFDALTNQTKPGYEYLTDLKKRNKPSLSDTQLLAIYSTITAFDYAKLDSGPKLLVFGIGHDTLFWCKANKNGKTFFFESDEHIIEKYSKDIFEELPNQYTDVNVVGVNYAAQIRYRTEYFIEPWLIDVPAPIEEECYDVILIDGPYGQRNSDVSENVDNFNILRLYVKKKKTARKDGSSILFSGDREEMYSKTREENTSLSGVPYNNMAFSDFDTKVQNFLTGFEFINEVKRKNRKISDNQLLAIYSTIKIYQQDKPDRTPKLLVFGLGLDTVFWCKANQNGQTYIFESEDNLILKYTAEVFEKLPKESTQINIVPVDFLAKVESADEFFKNPWIISVPQEIKNVCYDVIFIDTPQRDNPSVDGLGNPGKMESAFYAVENAKQCILNGSLDEVYIFLGDIDRQLERQIIQDFFWEAEQFVTVADEKGDLGGWKLNYNSLSVKNTYLNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U086</accession>
    <name>A0AAD5U086_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000316">
        <property type="protein sequence ID" value="KAJ3220059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U086"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042014481" evidence="2">
        <location>
            <begin position="24"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="236" mass="26563" checksum="EDF6169B0F5D0645" modified="2024-05-29" version="1">MFISPTKLTFLFTIFSFVAPLPAAPGAPPDNYGGSVSEINPLTAISTIPELPQSPSVPTDDKSDKTPEITQETSANDESVEQEETEEKKKSVEQEETEEKKEPVDDNDDSLELPEEKEDAEPIESKIEDETLNPTDVEIQTLNHNDNNQDEEPEATEIVNYVNVENVDYDHDSETVKEAVKESIHSTQDDNYASSKPKVYLNGDKHNIDFKANVKKMLELSPLFNKSKKKCKKNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0A8</accession>
    <name>A0AAD5U0A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SF3 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000328">
        <property type="protein sequence ID" value="KAJ3219739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0A8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="56860" checksum="38427E543BEF6F76" modified="2024-05-29" version="1">MIVKKLKLSNNRSSSSILKAHPDKKFMFYDDWPHSSELDHLLGERMLVIKTMCLFDKCLVKYRNSLYIFVPSEGSWVFSFSEVGIQYLCTRLDMTNVTVNGAIAIAPYLKYAYKIVDDVKPVPRSICISSYRLKVFDSKGELLLSRVNDLVDCHPRLPLRVKGFCCSPAINSNIIASKIVYEEKCEIYGILLNVLDDDALKVLIWTIGNGLIDPVSNSKLIYFRGDGGDGKTSLIEILESVLDGCIVPLTKDYVCLDKQLDNVDLARAASSRFVSCSEVTTNDGKINEKFWKMMTGGDLIASSFGDVRLRCTVFLASNVIWYKYNAISMKWFTRRTIVLPMKRLDRKATPPKAQYTSIEKSTFLFNCIHYRLVHKSIPITIKYALMTILGSGYTKIERCIQFVECSDFLDCYAAMICISILCLIDCETLVSLVEVMSKELVYKTDSNELFIKNIALTSESYPMGVNYTANVLAKEYMLDPMNEMNKDIELHELSDLEDDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0B1</accession>
    <name>A0AAD5U0B1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000341">
        <property type="protein sequence ID" value="KAJ3219397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39211:SF1">
        <property type="entry name" value="ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ASH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39211">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="817"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1288"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="486"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="829"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="886"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="3070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="3070" mass="345559" checksum="34D1B643D6F08017" modified="2024-05-29" version="1" fragment="single">MFEISLPNKLILENVYCNNIHALYRFEIRNVTESIINVKLRSNLGSQVAWQLENENLPSLKKTTSEDSNLFSSTSKSQQSTPSDANTPVEYDQSIIQTSNLVTSLNHRFNELFNQLNHVEEVEIKPKEIRQVILAFLPSDKKKKKDLVTSVNESNVILQQQQQINNAQLEREENFSVFVSNDEKDETFDFFEVYGLLFFFGYIVNDTTAPLTMILENNNDIAPETSDEKKNGLINTFPKISRATSKESSKSNIDGSPNLSPEFQMTVKFRAKVCRSYLWTDIGESGITFDDCIVGGTYYKDFTVWNRSEIDLYWLLNTVDLTNKVSKNLLKFSDYDTGEPFDGTAPVPAYSPRRIRVTFKPTDIGEFNYDLQVENINDSNNTISAHISATVRSVFQEESLVVSSGSLIDFGDCCAGMQSRYRLVLKNISESILDVSFSSDTPCVEFQLKLDVKLNYQSLAKSLEKLTLEKPRSSVNEVLSKATEISTSPSSNGSRASSPVLLREASDTGEIDQNSTSWVSSTVDLFDRADSENFRNENRSEELGRIEELQLRPGQEKTIECCFRPEIEKPGLDFKAGKLFRKTFRIFLNYFNPNSNEKRKEKKTIQCKARSSTSFIMVSPKELDFGDTDVGTLKSLPIAIFNLSELEAKVEIRFISKVLNTVRDEIRILPKQSVEVKVDIYPRKVNPDYRKQITVVNLLNRDNDQEISIRATNIDKHRVTFHSLFYRILTPMSTNFLDFGNVVLNAPTIRTFTIDNISKKKLVLELSSSLPDEIKTFSKGVCSPHSQKIITPTSTFNPIQRREIITEYLGDKKKFNRQMSETGPPLSFSPDSSTSALSNSSQDSRKETNIGDYLDLATNSSAAEKRSPKRKQNIKQTHTLKQFRLNCRERKMSVKSSGDDSKSATSKATPVERTFASELVRPSVRTTIINMAPSSLRTYLSKNNLCLMDMIENGGFSVDDIISLLEVMTGVLPPVYSKSSSEEKYIKAQTILRRDLGNLISNNSLVPASLIEIPPESELMIVLVFTPSGVTKPFIQGKPRKLDSKIFIKLIEFDKDVEHSKFSQLFTEGSNIPSRELMLRSSVCRSTMELGQKNINFGFVDKNEHRNKMIVIRNTSETPLLYTIRKSGSIGSGDIILGEGKVGIVRAYGKREVEFSFEPTLPGLYQEKLFIENIQDSENCQTLTVKANIRKPSNFFIQTLSIDFGVCLINDLGSIVQEIIISNTSEKQTRTFQLKVDTQSLTNIGCIPEITFELLENADEEYFEEVVEAKNDGSDQNMTVVLQKKKRKRQVLLLSKETEEEIEKLEQSLKIAKRKGNLDKVSKLNDKLDKLRKGIVDDEYAADEAKVSTTERSECDSENASLSASFSASKDLKVETKVDDEVVKCGMLADMTSGSFLSPSAKPPNLKNKKNESFIIFTLEPRQIKTVSVSFRPVEIKKEMTNIPLDSSENMEILKRAIDLFENQIDAPKQETCSGNIFVHELKNTDAMQLVNFHAVVCYDNATYLNALEAENQRPELLDSFLNSFSFDQAYSGIQQSSPTVTGGVVNPTSPNPELSISEQYLNVELSIIELGRLELNERKDCYFTLTNNSEKDVNFIVLDSLQNRETEFFEFSQSSTLKPKECKKYYGWFKPTLKGRNSATICIRSGISEDLLITFKWYGVLKSYLSFEPQLDLGFCYVNPSVKFAKVLPFDVTNIADCEIYVTAVSNLALQCIIFSDSLLENTLTDFLIPRNSTITVFVALQPYLSTTQNNSKIPESRTLIGGIKFLVSVVDNSDDLPPILSEPAGLYFQLLTQTVKFTSIIGHSLMNVSQNILDFGVTKELNKPLEQEFYVQNLSSKMPLEFFIDCTDDFVSIQQESGIIPGFESRIDVSLPYSRQLIRVTVHPKKFGLLNSQIQVMNKNSSYVAVVQVKLFVESGSILMKGPAIQEKADVANSVSTIIWEDQYIHLNEIEKTATFTLAQKNKTSSSKVSEASFELENCLSHPLTLSPKSDVDITLKYVVSSSSGYIISTDDDGGTYIGPDICIYAHQRVTVFVCAPKPTTASEENVSAIVNGKKLQITGNLTFENENNVVLGMLSLKSTYCMSRAEIDPLSLNLGKIGHSNSWKEVPFTFTIRNLSEIPFIYNVALSDAIEITKVDSTEITNDHKIATKRKIEAKGIQVISGYLNPMHISEKIAGPHTFNLHLVNLFNPSNDISLNLIAQLTLFELKFERLTAGELVLPTLYYPEIPGVVGSDTWFAIINTSEDDVKFEIGVNLAPDVSEIVRVEILSRFSNTPLIGSTTLAPGSDIEIRVRTYPKDSTTRLPPTESSKYLINPDGITFGSLTVCPKKHPLSDLGLVLPRTVENIPIRGNIVEQPIFSITENHLEFHSFIDSEDEEEKNYKLKRRSSKSSGKARRKSSDSQVAYININNLSTVFPLEFSVTTEYPIELPNGIEIFQIDYLDEFMQGTVAPASSLTLTVTLVDSSISGVSDNVKILITDINSLSNHTQTIILNIIQETSISRFSLNEKHENNVIEKHLSTSPSDMVPMENGQLNETVSVVEVDDAVSFYDENKYLTDTQLSPHFKQDKKLSDNVRKQVINLRGCKKLNQYDSGGLFELDLGQQDLGTMNVLRKIYLESSDRVSYILKSFSENDKSWIIPSRYEGTLEPHRVGSVSNKDSHQITINFMTGQRGVYVTYLVIENVDNPLDTKTIRVYMEVVAKQNVRRTAAGNIISSIAGSSGIENPSIHVFDVYANGVDAEAAEFDIDCFYNTEYSARSIIICNKEAVPLDLVIKSNLSHDDPSELFFSLARASVKLFRTLTVPPESSIRVYIQFIPFSDKTPSGTLAETENQVDEKLIELTINCRLVKDYQKIIPMRALCRQPQLSISADEASFSGVLERKFGTQSPISPENTVENYVFNVNFKQHFQEIVIENILDEDLIFEIFNDTSYFVTSCNLIPISISPSITLAGGNSISTASGSGILDQRQWGSSGIYCLEPRQKTFIQIKLNKEMILKNVDLFWKEKYLIEHLTVYNKNRPFEKKFIVLKLSFGNLKNFDDASCTRYNFSTLESYVVKLLREIDIINNFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0E4</accession>
    <name>A0AAD5U0E4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005991</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0415 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000493">
        <property type="protein sequence ID" value="KAJ3216170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0E4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010733">
        <property type="entry name" value="DUF1308"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041076">
        <property type="entry name" value="DUF5614"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13379">
        <property type="entry name" value="UNCHARACTERIZED DUF1308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13379:SF0">
        <property type="entry name" value="UPF0415 PROTEIN C7ORF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07000">
        <property type="entry name" value="DUF1308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18474">
        <property type="entry name" value="DUF5614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5614" evidence="3">
        <location>
            <begin position="39"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1308" evidence="2">
        <location>
            <begin position="266"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="496" mass="57019" checksum="E31EE846369DB957" modified="2024-05-29" version="1">MELIDQVHGLILTCRNLQLEIDKIKATQNPKDLSKLNSILNKLLQNPNSIKRIHIVSSNIPYLAAVISVIRNETGVISVFQKFLRSSKKLSKKDIISVDVISNYGRKWIKVKAANVKNIKKNLLYDFIEEETESNEFFLVNSDEEECDFITSKDESDDVKLIRQLKDMVTVSEKNLVHYVAPAVVVIFRVDNEDSIKSLEDADTLINNDEIINKFREIGVGAEVLVTSNEVFCCKKVLCLGKTVLTDDKKGESNEKIDQLSNTLLLDITTLIALCSNLSYKNSFTYDTKFKNECLQYQLIQELQSPLIIDLKKIFHGRKLITTKSVVKKLFSIVSTVGGKTERYRSKKIFKFEELKDYGLVETEVKDNKVFLEQDLDFLTQKSVEILENLNISIVNDEPSKKFELILKKKKNFKKKKNSNIPKIVKDFNLIIFGTAEFYKATIVTANKNFVKTLKNIPYEDLVDDNEEHAVDLKIFNCSYYLHESRSFVEQSEQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0R5</accession>
    <name>A0AAD5U0R5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">5'-nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000387">
        <property type="protein sequence ID" value="KAJ3218294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0R5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000020">
        <property type="entry name" value="NT5E isoform 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF24">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00785">
        <property type="entry name" value="5_NUCLEOTIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00786">
        <property type="entry name" value="5_NUCLEOTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041766083" description="5'-nucleotidase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="7">
        <location>
            <begin position="162"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="8">
        <location>
            <begin position="466"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3218294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="662" mass="72862" checksum="C7AB85E302B57E2C" modified="2024-05-29" version="1">MVKLSISLPFFLFSVATAIPLDTQLEGCVDNSFLWSYKLNDPVWQNLGDSFFNQKYNLKSILDSTAFPGVYYDLAREWLTASLNQKNGATLPETSRKAQHASYLLLKDNVKQTSVITLESAVTSSGKSYKLADLLQTLTDYNNGVNKDSSPPTCASKAQSIHVLHTNDIHSHFEQFNKYGTDCTADQITKNQCFGGVARITSLVNTLRKKYENSILVDAGDQFQGTLFFNTYGGSIIANWMNDIKYDLLSVGNHEFDRGVHYLSGFLKSLDFHKVSANIEKAHIPELVEAGLKPYAIFPQYKLAVIGFITNTTGDITNVKNVTFYNPVISVQKQIDELHSKGIKRIICVSHNGYSEDLYLAKNTRGISLIVGGHSHSLLTKFALPGAVGSYPSPTQNLDNTTTYVVQAHRYGDYLGDVEVRFDENDNLTFLDGNPILLDQTISVDERTAKQVADWKQVFEAETKAVVGAVKEDLLNSQCQGGECLLGNLLANSWLEWSQTLSDKGHISLVNVGGLRASLVKGNVTVANVMAVLPFGDSIVQFKATGSSLWQTVQNTVNGVNPDGTKVISLPRFVGLKYTYQASDKVLKSIEIQVDGIWSPIDLNKQYNVIATEFVANGGDNIFRPAPTNGINTGMKVDDIAIQYFKKYGTVDVSLVGSINVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0R9</accession>
    <name>A0AAD5U0R9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="6">M1Pi</shortName>
            <shortName evidence="6">MTR-1-P isomerase</shortName>
            <ecNumber evidence="6">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">MRI1</name>
        <name evidence="7" type="ORF">HK099_004379</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-(methylsulfanyl)-alpha-D-ribose 1-phosphate = 5-(methylsulfanyl)-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000306">
        <property type="protein sequence ID" value="KAJ3220325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0R9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.420:FF:000003">
        <property type="entry name" value="Methylthioribose-1-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10470:FF:000003">
        <property type="entry name" value="Methylthioribose-1-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="entry name" value="translation initiation factor eif-2b, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004326">
        <property type="entry name" value="PRK05720.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00512">
        <property type="entry name" value="salvage_mtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475:SF1">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3220325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="41187" checksum="EC8220551D232074" modified="2024-05-29" version="1">MGGIVQSETLLAIKYSRGSLEILNQLLLPFQPVYDKITTVDDGHDAIRTMRVRGGAPAIAVVASLSLAIELNVKSFVNKAELNQFVKEKLSYLKTSRPTAVDLFNTIGKLLSLSENFLNDTVLNVEKSKLKLIEFCEAMLQTDVENNKNIGSFGSEFLKNYYKSSSLSEGLTILTHCNTGSLATAGWGTALGIIRSLNEAKNLSHVYCTETRPYNQGGRLTAYELVYEKIPSTLICDSMASALLKTKNVNAIIVGADRVCANGDTANKIGTYQLAITAKYHGIPFLVAAPSTSIDFSLENGSLIPIEVRNGSEVSKIKGLDEGDGKLRTLKISADGINIWNPGFDVTPADLISAIVTEKGVFEKLKDKNVFNLKKEYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0S4</accession>
    <name>A0AAD5U0S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_005705</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Microsome membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000458">
        <property type="protein sequence ID" value="KAJ3216836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0S4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000002">
        <property type="entry name" value="Cytochrome b5 type B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF150">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0492">Microsome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="14">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3216836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="100" mass="10782" checksum="ED94597576278704" modified="2024-05-29" version="1">MSAEVSFAEVSKHTTAKDAWMVIDGNVYDVTKFLDDHPGGEEVLLEQAGQDASEAFEEIGHSDDARNLLKNMLVGPVSGAPKVVKKEEVETKKVSSTPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0T4</accession>
    <name>A0AAD5U0T4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000613">
        <property type="protein sequence ID" value="KAJ3214533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0T4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="66" mass="7895" checksum="6A694AB4A1687774" modified="2024-05-29" version="1">MLDKGIVPNTLVYEVMLKSYDELGKVQNIKEILTEIKNDKVKFTDRRSNRLKFYSKKLNENMKQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U147</accession>
    <name>A0AAD5U147_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003853</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000259">
        <property type="protein sequence ID" value="KAJ3220984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U147"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF19">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3220984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="238" mass="26625" checksum="F9BA65A1CBD85079" modified="2024-05-29" version="1">MFISKAKTMNSVTSNLLKDPALLTTPFSTKLPVTSNIARNWQKELFFNSQRDLTGQLSSAVCSGEEKGHSMQVLSDSVTQLNSPAATSEPCCSLTPFASALHFFDGGQEEVNFNSNQDCRVYTSLTNNAFGSEVKPQYVRDYQDNNYLFGDSKIENTFKTENTSCVFDNIATIKTTGHACSTCGRVFARKYNMKQHATIHSTNRVKTHYCSICTRSFYRVADLNRHLKIHTRKGQLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U164</accession>
    <name>A0AAD5U164_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cation channel sperm-associated protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CATSPER4</name>
        <name evidence="10" type="ORF">HK099_003912</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000264">
        <property type="protein sequence ID" value="KAJ3220905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U164"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036128">
        <property type="term" value="C:CatSper complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030317">
        <property type="term" value="P:flagellated sperm motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028744">
        <property type="entry name" value="CatSper4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_bS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_bS16_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47077:SF1">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47077">
        <property type="entry name" value="ION_TRANS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="Ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="9">
        <location>
            <begin position="131"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="558" mass="63927" checksum="EB308E31918A6453" modified="2024-05-29" version="1">METATDLEMTTARAQTNKKNSSYFSDLPTNIVKKESLHSSKSNLDFLEEFKDHVNLLKESNIKLPEIEKDNTDSYVKVRRIIFGQAIKYNIQKIEKIYTTFSDIVDIDEEGIDSYIKENLATRFGEGNFFRLLLRILKVIRTLRSIKSVAFIQGLDMVVSTIIDSIPDMFNIGVLIILTMFIWSLVGVSLFSTVDYHNFGDIGKTMFTLYVVITGDGWEDIYHELAHHGYFVESSFFFGSFLTIGTFILQQVIVAIVVANLEDSQHKINLKKKKAKQIFKSEIKSTTGQKRPIVPKPSNKSKIWMDQIPYEIPNFDNISIAKLERYFLVLSIIEDNMYEYLELKSRLHAILNEVQIVNENVVESKENIGEEDENFVKEEVAAPNKFARDGRHLERLGSYNPHPYSEPNFSSSEQNLESKKNISVKHLELNVERIKYWLGVGAQPSSRVAWLLAKAGLMPKTPMQLQKEGLNSFVDKKQWDIQVSDKEGNRLGVLSSEEARKVFVDENGKLAAGIPEEFNFIKEQRIVEDLADFNLEGKVKGKLTPPQKRKLLKSMLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U199</accession>
    <name>A0AAD5U199_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000249">
        <property type="protein sequence ID" value="KAJ3221137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U199"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="613" mass="70603" checksum="B674AFFA5EC3611D" modified="2024-05-29" version="1">MIQSEDILEEKKIDPTTEVIGMSELIELNKEENKVAKCYLEDKITRIKLSKKEKLDKEKAVKKELKRPHTTPSIGTVKFQVNQYNSETFRPFLIGEIKPKVLTKQISEPINKDKFVNDKNLTQIKNKQELRTKSAPAKYDLEVIPKWDEKELNVILKVNEDVLHSNSSTNNKGPNVDNTENTEDLEKKNFTRVSRSSFTNNNFEKKFSKTSGDINLSVNLNANIRNSLILNSHSNNSLSKNSINCNTDNFSVSNKPRVNNANEVATSIASNLKNSSENTPVGDGIKEKDLRKTELKSLVQVSEACRLNIQQFEKVQNKKKHFTKMELDQANRIPASQFKTNSHENYCAGVTKNSNFTKTHKQKLEEQEVLDKKNLEKNGRQVLESLKNLKKNKNLIWEIKKKKKYMLQGKTNLNSILDLNCRGPGWFWSKNPKNKTWNSILGLKDDEEINFSTAVIWPSKKAGKGMGLRNIETCNGLTVSGTAGEERICEVDRSQGILRKVENVEEFFRVKNKICRSEKNLNKLNNVIDIRDQTENKNAKTFYNVINDYEGNALDIPKRRDIIKQLEPRIQKTWVKESDNNRYRVNTDWKIDTKTLIQAPETGTYYMHPRVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1R3</accession>
    <name>A0AAD5U1R3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Muskelin 1, intracellular mediator containing kelch motif</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MKLN1_2</name>
        <name evidence="6" type="ORF">HK099_003536</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000230">
        <property type="protein sequence ID" value="KAJ3221442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052456">
        <property type="entry name" value="CTLH_complex_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010565">
        <property type="entry name" value="Muskelin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15526">
        <property type="entry name" value="MUSKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15526:SF5">
        <property type="entry name" value="MUSKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06588">
        <property type="entry name" value="Muskelin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041970083" evidence="4">
        <location>
            <begin position="20"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="domain" description="Muskelin N-terminal" evidence="5">
        <location>
            <begin position="689"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1299" mass="145522" checksum="0B9AF40296873255" modified="2024-05-29" version="1" fragment="single">MHPNSILTSLALTLAVSSAFNLPEYLQPASEFVINEVPPPSLIQPTPKSFEQKQQIATDYLVNITGTPKEKISLTSSVESGGKVLNFHFAPTEEGKIVDNANGNVIVDDNGNVLSYGLAWLPKGNAAPLSLIKTATIDSNTALKNVAAALNLAYDEKALTIEEVDGVKKISNFGEQVKGVIRISEKFYRTTTTLEKCFNVVLQLSTSDYLTIFVSQNTGKIIAANNWLVRDSFQAPKKLTKRETTYKYNVLGFPKADLTEKREILINPADKTASPLGWHNVGNGDVGTTTGNNVNAQEFQNQNSPKRPTSSTFNFDYPVNEAKSPKTYWEAATVNTFYVTNAVHDIAYKYGFDEKSGNFQKNNFEKGGKGNDLVIANVQSSVIVNGQNTNNANFGTPPDGYEGEMNMYLFTSTNPHRDGDFENNVIAHELMHGITNRLTGGPANVNCLNTKEAGGMGEGWSDVNAFVLTTKATDNRNTDRTTGSYLLNNAAGIRKYPYSTNMNTNPYTFKDVKALNQVHATGEIWATLLFEVYWNMIDKSGFSTNMLDNASGKGNTDFYQILLNGLKLQPCSPTFLSARNAIVLADKNLGSKYECEIWNGFAKRGMGTGATSSFINNYEVPAACSGTPPVTTTTTVITTTTTTATATPCAHDKCVVGDALKANCDSCVKKICDQDSFCCKDSGSWDTICKNAVKSVVPCLYLKIVPLLAHGANFNFSIWYVEVRGTSDAALLDKTYKDYVNYKENEVIRLCLKHFRQRNMLEAFTTLHRHARESYEDPILSKLHHNIAMEGNFIASEEILIKACENSLFEEYISGYPYKPLWSRIVLQPNNPSPPMRGGHQMCIDVEGRKIYIFGGWDGQKDLSDLWEFDLEKELWKCISVDTRRNGGPTPRSCHKICFDSKMKVIFVLGRYVDPESRPNVNLEGDFWAYSVPESKWTKLSHNTAQENGPDLIYDNQMVIDSENQILYSFGGRTVGPDSSVVNYAGLYSYNVRTNKWTLLRSDTAQPTTSVHMKSRIGHSMLLDPKEQILYIFAGQRNKDYLSDFYTYDIKTDTVYEVSRDYSVQGGPVAGFTQRATIDLNLGEIYVLSGLMKEKNNPTEMVKNSFWVYNIQKSKWSKIYQNNQSGHDYWEKTNDFEPIPRFAHQMVYDDVTLRQYMFGGNPGESSHPNLRLDDFWLLTLERPKPFDILRKAQFLIRTQKFREMCQNPSEALHYLKTSVYTIVDHSNADESAEFRALPWILFGWSTHNRLGWSELNHGDGGLLGSANEGNYGSRIELFENLLKFFPKSMKEPIGSLVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1T4</accession>
    <name>A0AAD5U1T4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003287</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000218">
        <property type="protein sequence ID" value="KAJ3221631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1T4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019188">
        <property type="entry name" value="SNAPC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15131">
        <property type="entry name" value="SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15131:SF3">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09808">
        <property type="entry name" value="SNAPC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="360" mass="42332" checksum="5C801D0725F0088E" modified="2024-05-29" version="1">MSNSIKRKGSHYDVKTISHYNTWFEMGSTQISIKALNNDIKELLLNFTKKETDSFREFNNTCEEFKFNLIHVICKDIPRRNSFYDLIFSLTFALFFQYSDKHFKLSVLYLSYYLFFTQPANFEKQYIRILPSTLTSLVRVTKSFKEEGKYDPAFVFNCLKSNDCFIIVAVDYFGKTETGFENFSKTLDQIKNNLFFRQDIILNKLQELKKILKTYNQEKIENLNNVILKNQHKNDLNDTLILECINKIQKKNNNFDDLVNLEEVSILDVIDSKKCEEKLNIFWDNFNSNANFLKNFLESGNVDELPPVSTKDPLEINKEGSDQDKEEDLMMQLNIENETLFGEDGNLLFGDLNETRYSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1T7</accession>
    <name>A0AAD5U1T7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005312</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000407">
        <property type="protein sequence ID" value="KAJ3217841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1T7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007191">
        <property type="entry name" value="Sec8_exocyst_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048630">
        <property type="entry name" value="Sec8_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20652">
        <property type="entry name" value="Sec8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04048">
        <property type="entry name" value="Sec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec8 N-terminal" evidence="5">
        <location>
            <begin position="27"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec8 middle helical bundle" evidence="6">
        <location>
            <begin position="286"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3217841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="596" mass="68835" checksum="A46380F4423F0F37" modified="2024-05-29" version="1">MSKPPNPNQATAKVEKAEVVKQLPTEISDVMNEIQTFWNFMTPETFNPVPHSLTLLDSSSLGRDYKSFLKIYEKLEIAMDIIVNDYHQGFNNAIQKFSGVVENIADSKTRVLRMQSDLENCKDWLQNKRFDLFHLWIKSLQYSEMIRILDLVEGLMDVKKKLKYLKQEKFVLSACKLLLSSIKALNSVECQSIVALENIREKLKEYKKTLPELLLDELQNHLYLKSPYSLYRLENDANYEPESRVDKNIEKTFAESASIKAFRAQIAKTTKFFDDKEILEEDFDRNPEADSYTYMHSIVLGMHLLGNLPKSLKTLNERLSLELHYVIEKTIQEVDLRNEKILMTLKDSRAVDSKTNVTSNLVANNVNNLTLKTSDYKPDLIGIEKKIEHSKVFRDLLNSLYRKFEVIVQGHFFVLHVAHSIAELDQVEGVYTIRDVWFTVQNEVKRLLYDYIANVDQKKIANAVISMDEVMKKKIQDQTSKQLYRIMNGNFNLKIHDLYKNISGNEVYGNAEDLQTGRDSVTNDILKRMKEGGGTDKVANSGIIDKFETSKTVGRKLLLSSDPYNILIAFEPTCEFMENVEETIGVRFPILLSERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U243</accession>
    <name>A0AAD5U243_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000221">
        <property type="protein sequence ID" value="KAJ3221586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U243"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="239" mass="25403" checksum="B60E20D13666D80B" modified="2024-05-29" version="1">MSCRCYCCSGLNCIPKYVDDFSVFAQADCKTETCTVRRRKQAGIGPNQCKTPIKVNYFLNKNTADNGTQPSYQHQPPNYQQTSYPPNTSDNYVSYPPNGYQQNSYPPPSNAYPPPSSAYPPPSGNPPPSEPYGNIQRLGNGGLLGKNNIGGLFGKKNNGGLFGKNNTGTGMATGGAALGVGAAAGLVGGAALGHALSGGHHSHYGHNDYGNDYDRGYGMESHNYTSNVGDTYAVESYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U270</accession>
    <name>A0AAD5U270_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide repeat protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TTC29</name>
        <name evidence="8" type="ORF">HK099_004166</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000289">
        <property type="protein sequence ID" value="KAJ3220593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U270"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051476">
        <property type="entry name" value="Bac_ResReg_Asp_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46630">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46630:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="253"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="427" mass="48659" checksum="091F81C4DCC8B1B9" modified="2024-05-29" version="1">MSLISSAKSHKSSIADFSNFPTQLNDEYSNYSKQISLDLLINGHVRSFGDFFSLIIHQKKEQQNNIEKLQNLRQLLTNAEISQRSGNDRAIYQSRTSIAKYFESIGDYGLSIIYLRDTLEVSSKLSTQDNSKTELEALINFGIALEENNKLEESLIYFEKSLELARANGNVDMESCSLNNLIKIRLKISEKFERSLKFKNCIENLKICLDFLKLTSILNEHNASNHIASGAIAVGVNGEAVNERESHEVNLAYEINFKLGLCYKEVGDLELAIKYFSTFLDMCKKTGNYSKEGKAKVLLASCYELSGDTNLAINYLQQFIAQSEDKQSQKYALNDAYFLLGHFNGKSGEFEESERYFQKHYELTTQLLNENNAKLKVNREITNSASNTKKTYQDSAKSNDAKYRTSSFEVNEQQLDEKLGKKEYISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U290</accession>
    <name>A0AAD5U290_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004545</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000323">
        <property type="protein sequence ID" value="KAJ3219884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U290"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF247">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="336"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3219884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="457" mass="52676" checksum="8A3AFDBAD03F3F3E" modified="2024-05-29" version="1">MGKSLKRLQKKRKLNEINKIFSANQNSEQCNSFQELGITDEDLKSTLKVLAHLNKSSNFNNQEFFSVKKEIFNIVQNSQLEKNNKINLKITNLLEEKHFNKAIFQLKLNYLNNIKLGTVQRWIRLASLNNSITARTNEESTEYYRLLDMIIRVSDPSQIFALEDSEDFHMEYPSLRRFQPFLIPVNSVIDNKATDTSNMNDLKCSSNLNFNFKLLISEKNLKMETHIKIFTLDNSISHDIFDQNYHYDRMIKKLTLPFVQKSFILTNVFTKRECENLLIASDSIGYVDDFGYSFSPDASEGAAGCVWLMEDNLMNPIFERVKQLLPQELNDKALTGLNARFRFYRYSKNALYRPHVDGSWPGSGLVNGEYKFDKFGNQWSCLTFLIYLNQDFDGGETSFFWPSTGEGILNVKGVKPSQGCVLVFPHGDTSGALIHEGSQVTDGFKYVIRTDVLYEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2A5</accession>
    <name>A0AAD5U2A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000197">
        <property type="protein sequence ID" value="KAJ3221995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2A5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="724" mass="83839" checksum="714D3CC578E8DDD7" modified="2024-05-29" version="1">MTTKKLLNNSKINHNESFILNDKFISKSSIIDIKNLLTEKQKELDEKEKQLIEKRKLLQEKDNVILSLIDTKSVLQNELTKKIIRINELEEYISKNKKLLQGKEAVFQEKFNAENVGITEEQGIVEEVVEEEFTVAPLKIASDLTASKLSYYKESNKLNGSKESRKLGVSIKQPMESFSSVPLQNEKKLSKIVAQNKIQYIKNSVFSNDIIRNTNKLNHLNNIDKKKEKMKNCDDSIKFDKIFVNGICNTSELLKEKTSDLNTSRGEVNVNRKSTQIFEKKNLSTSAKSEVTMIMEMILNLNDVNSMKNLFNLNLLKRLAMEEGLFNKVIGKCLNECKKSMHNGLVPKFHFDNRNNKKLALYLGGKQLLSMQEKIGTSQGNCLTLHEENLGHHVVDRYVKDLHYSIIRNELKPNSLYTACLKSRILATIWKIKNSKFKPLVLLFDLLRENDFDLTWKSGFFNDFCEKKKNEEIFLPNFILPIYYNIIFVWKGVLSNNLDRRQCCITEITIKIIMHNLSLLVSVNQNIKKKVSSFLLIDTPIPNISEHLQELVKEICCRIYNVYHPKVSPNESKTESQLQEAELFKSLELCCNHVTWDERFEVIQTFWPMLADEKHNAKVLHLISSICRESLKQSSSSLSKKLNLDWIRREFGIILEKFKFESTLVGNGIEFNIAKVLFELLLLLPAKDFNSYCAPLQSWFTALSLEKLKLMPVEFKAELEYIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2S9</accession>
    <name>A0AAD5U2S9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000392">
        <property type="protein sequence ID" value="KAJ3218171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2S9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="137" mass="16382" checksum="981C930F409F04A9" modified="2024-05-29" version="1" fragment="single">CMLENYQTIQKVEIVNPTHNSGNSLATTLFPRGYTPTQQLNEELKNKYLQRREERRLQQLEYQELYLKQKILNNNKFKRYDSLKKKRNLNMHQKLEKAESFSDLNTLKKNNEPISTERSTIRNTLEMKDLFQIAGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U388</accession>
    <name>A0AAD5U388_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ammonium transporter AmtB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004428</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000310">
        <property type="protein sequence ID" value="KAJ3220226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U388"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097272">
        <property type="term" value="P:ammonium homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002229">
        <property type="entry name" value="RhesusRHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730:SF60">
        <property type="entry name" value="RH50, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00342">
        <property type="entry name" value="RHESUSRHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="7">
        <location>
            <begin position="19"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="573" mass="63929" checksum="D82CADDFA3B7B00F" modified="2024-05-29" version="1">MMIGVTSRVKDCIHTTKMCIFGFLMTFLKKYGFSSLGLTFLICSTIIQFYPIMKNIMHNFFLNNFYNLTKFYLNVEYLILSDFCAASVMITFGAILGKVSATQMLIIGIFETIFYSLNEEVATLFNITDVGGGLIIHMFGCFFGVACSKLLTPSNAKTSKDSTSNHSSDLFAMLGTIFLWVYWPSFNGALATGDSRNRAVVNTVLSLTGSCVSTFIFSKALRDKRKFHISDIQNATLAGGVAIGSCANLPISPSVALGIGFASGWISTLGFTKLQSLIEKHLGLHDTCGVLYLHGIPGMLSGISNIIIIYFLNETKFSSEQTFISIFPLVHSNKLTFQQQSINQLYCFLITLLISLVGGIITGVFVKLVTSNNNNKSSTYFNDIENFELSNEDESRFLISENQLDLERADSATNATNYTALENRLKILEEKIINLTGSLPNVNSDHPKIWNPSKIAEKNDFTFKDDYQNQNSIPRNTMAFSTQRNEGLMQSNNFNQNFNDDEIGESVEEFGEQENYLKEAPDAYGNSQNYGNIESDSMQNCNYDIKNTSAEVNDAEGMEENVEELLVDNEEYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U485</accession>
    <name>A0AAD5U485_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005087</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000382">
        <property type="protein sequence ID" value="KAJ3218397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U485"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000005">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="8">
        <location>
            <begin position="365"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="71"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="183"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3218397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="762" mass="87393" checksum="89BDC2297921AC11" modified="2024-05-29" version="1" fragment="single">PESQPSSTTLSRRTSSPLSVVSNSTLAQENTDVTVNTKTTPTTENTLKRRTMNSREAAQWEDTTLIGTIVEHENTEKGEIDEPNSELTLANDQEEPQKLETTTRKYKKRKRNKPAALNTLNLNESPGPPSSIDSDCKRLTNSKRFTIYEMKRRVKAMLEYMGSIDVNSIKLNSADLNSINPNSCNLNSIDTPNNKSSEVEESSSSSNSFQNNIPPNSQHKIKRNIFANNSNFTTAEKHEIFQMYTNLNKSLEKFQTKYLSPEQWLETIKQCKILEEQDIKQLCEMVKDLLMEESNIQPVHTPVTVCGDIHGQFYDLMELFRVGGEIPTNSYIFMGDFVDRGYYSLETFTLLMTLKARYPDKITLLRGNHESRQITQVYGFYDECQNKYGNPNVWKYCCSVFDYLTLAAIIDGRVLCVHGGLSPDVRTLDQIRTIQRCQEIPHDGAFCDLMWSDPEEIETWGTSPRGAGWLFGSKVTSEFNQVNNLILIARAHQLVQEGYKYMFPDENLVTVWSAPNYCYRCGNVASIMHVDESLQIDESKFQTFSAVPDTERLIPTRQRLNIINREYDYIKSTLKNRVSFVAQFTESLKDKTSEYLTVFELQQLVELLCKDFPFEVTEISAKIIGSNIVLPTFEKSNSREYSCGYEKLRISDVGKGFKIYFTYVDFFNNTMKLLQECSVAILRENSPQKVHTDELKLLEESFKLLIKKQYSKSVDLNAHPPFNDIKEAITKTFKVQKVMQHQGPNLVPVIWYELVYNLGLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4E3</accession>
    <name>A0AAD5U4E3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">KIN1_1</name>
        <name evidence="11" type="ORF">HK099_000446</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000110">
        <property type="protein sequence ID" value="KAJ3223962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4E3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KA1" evidence="10">
        <location>
            <begin position="741"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="281"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="353"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="652"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="652"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="786" mass="89429" checksum="409045EF7EDDB972" modified="2024-05-29" version="1">MQCKTLISQMLNPNPALRCTMEDIKNSSWMTKGYDGPPDNYVPVRQHLELPLNLEVIKRMKGFGFGTDEEIKCKLEDIIQKRNLLKQQQSTFHNEKESKNNFFRKENFSAQKFDLKGVGRALNKSKSEKWKPGLPEYSIVSIYYLVQEKMEKDISSGRISVVEKKENQVVEDNNGATRQNNEDIMTDLEGRSSVESKLIQNEEVENAIPLSSDNEESINALSAPTSPRLSRKDIIFIDEQPVKKRRSRPRAASMGELAIPNSMKSFKEIKDFVGRKKKKRLSKKVITEAESESDLGDSERVEKDLENTSPLEANLSESENDIFGSSSNTEGLGAGLGEKKKIASHLVSAVKKKMSQFGNRNQRNSSSNKEDLLDRETVSENEVESLSPSTVPFQKSNTIGTGPRNSRLSRNRNEFGNNPKRHQNHFNKEVSGTLVEDISSVKEEKLHRMKKRRSLGNQFQSSKSFFQGDDIKFNKNDIHDLEIEIVTPASSPANPTLPTSVIHIAGDVTDKSHYKKKERVDSNVKKVFMKGLFSVLTSSTKPTSFIRKDLIRVFQFLNVEFHESGLQLLFNYFYFLLDGVFECRYIIDLKKNLPNSPAEEKSNVASKEDKEKAEKKLEITDDLDLFHVGSEEECDQATSSCVNNGNSNIKRVSAAQQQVPSSPQDKPPKLPKFPSASNLKQKIQQQKLEHQNDVILTSAEAEILKVNENIENLQPDKLKSIETENASINNNRNFLIPMNIKTFNSTTVFFEVFIVKIGWIGLHGVRFRRIEGNIWQVKRNYLFEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4G3</accession>
    <name>A0AAD5U4G3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000179">
        <property type="protein sequence ID" value="KAJ3222354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4G3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042099499" evidence="2">
        <location>
            <begin position="19"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="492" mass="52758" checksum="9B518C3FCAF3D2DC" modified="2024-05-29" version="1">MKFSTVFAIATLSTSVLSAPHSTTPCSTTPTQSVVPSKESKTPCSTSTTSTQSVVPTKETKTPCSTSTTPTQSVVPSKESKTPCSTSTTATQSVVPSKESKTPCSTSTTATQSVVPSKESKTPCSTTATPTQSVVPSKESKTPCSTTATPTQSVVPSKESKTPCSTTATPTQSVVPSKESKTPCSTTATPTQSVVPSKESKTPCSTTATPTQSVVPSKESKTPCSTTATPTQSVVPGKETKPAYNGYAPTQAVVPEKESKTPCTTTEPKNDTYPTQSVVPTKDTYPTQSVVPTKDTYPTQSVVPTKDTYEPSKSYPTQAVVPVKENAYGDYEPSKSYPTNAVVPDSDLKPARKHKCKKHSYKPSYAAAVPTQEASYGKTETSPEQVNKPAYGVQESLSDSENNLDHGGDKDKVLNIILRLKQLQKKQKSEIEFLKFKVKILTESLKNNLTYNEISNHIPFRNQDSKIKLYDTEIDEENEVEIDIVDLTAKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4K5</accession>
    <name>A0AAD5U4K5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000246">
        <property type="protein sequence ID" value="KAJ3221182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4K5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="118" mass="13889" checksum="EE9C6A2FC9BA07E4" modified="2024-05-29" version="1">MDSGAFKGSMPKELVEMPNEPPPEDQSWVPNEHQINRQRQKVDEKFGPGAWRKVEDKIKPHRCNPHLQDFLISISYYPFNYAKFSAYILFQCFRSEVGKEPKRFMLNPNTGEPFEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U542</accession>
    <name>A0AAD5U542_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein phosphatase inhibitor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000137">
        <property type="protein sequence ID" value="KAJ3223253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U542"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007062">
        <property type="entry name" value="PPI-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398:SF20">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398">
        <property type="entry name" value="PROTEIN PHOSPHATASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04979">
        <property type="entry name" value="IPP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="25514" checksum="279EAB32D245D530" modified="2024-05-29" version="1">MENLEFNSESEIDLNETLNHPPSLQTQPKKGILKRGRHENDSNSKIHWDEELITFHDSQRGKTMKISEPKTPFIHYDQDNDVLLGHRGGDFVEIFYCYILKNYFGVDDIPPMELMEAIRLASDSKDISDLSQEDNCSSKIFNQGDVNGKNANNKKKNFDEWNDSESETEFEDIQKKKEFDIHRRGHYENMKEAMLRGKHLVEDELESDIDDQDKRMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U564</accession>
    <name>A0AAD5U564_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000305">
        <property type="protein sequence ID" value="KAJ3220426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U564"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="55" mass="6208" checksum="7B36BBAE22E0D3B1" modified="2024-05-29" version="1" fragment="single">YEMSFSLGFLNLILSVELIIFNMLIVESFDNSALEKGPKTVSIENMNKITNPITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5B6</accession>
    <name>A0AAD5U5B6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000206">
        <property type="protein sequence ID" value="KAJ3221832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5B6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039786">
        <property type="entry name" value="EFR3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766:SF1">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="823"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="846" mass="95357" checksum="205606EBCD412E46" modified="2024-05-29" version="1">MSALVACCCSSKKLTAVQICDAVYPADDSDKPISSNLSKLTFLLNQHPAKLSSVFNHILNQRLKKDVAPNLLIIKEILKECSQHLLLYSNFVLEAISETINKEYLTTTSTYVYTAFNNCWNFQQNDLLNVYLSTFKIYCDMLNSSKNELALQAIDSAAKNPNFHSSSNISEFIDLMVPGVLTLYYQQLLPEGSSSSPTSLKDLSKTATIKFSNMSSIIYSTQTEHISTSKGIVKLSTDFITSEPAEIPKMSTEEEKVKPNVIVNLCKSVLLHIAKDSSTEIAKKISNEAIKVLLTFNNLSIIQTIFNQIIKNFFDFKPQHLYIHCNNLTEMLESNTVNLKEKYISIILLTDLISVFGPFNSLELCQVFSKLIFENIEGSTDEDEIIFKSALTEVMGSLGKNIQYPEQVNDMLTYLINRLALPSLSSVMGNLNEVSNNSQLSVEANKRIWILKCLIAMTNVRLRDSKSPEGKELRKRCSITRKPVAHEVMSPLLTFLGDTSAELRALVSTLIKDLILMELEEFNVSETRFHRSLIRNLYIYIKSPNNVQQDFNSIFDIVKVLIQKGGRALIETLRMILTLENEVCEDLQYDEKHSNIIGNLALSTFTFLSRHWGFKDVEAFVLDVKFERIAEHTIGIDVYFNLQLTEEHVTSSKTESKKLTKSLRKTGIIDAIEKNVKTVTATEKEESSCENFFMFYCEHQNFLNDLCLDYKYLSSSSNTNENIYLDPEDIVIKKHEYSVDSLNAFTANFKSTKPKNPNANIQSPIDENASATSSQDSLHNSAAVLSTTIVDIKKALNSDEVEIEMSELNGNTHPSEVTDLLDSLGTPKRQSNINSTILEDLKEPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Q2</accession>
    <name>A0AAD5U5Q2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GDP/GTP exchange factor Sec2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002714</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000192">
        <property type="protein sequence ID" value="KAJ3222099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Q2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21044">
        <property type="entry name" value="Rab11BD_RAB3IP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25555">
        <property type="entry name" value="RAB3A-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="4">
        <location>
            <begin position="311"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="590"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="343"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="591"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="607"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="744" mass="84979" checksum="9BFA96FA9DBFCAD7" modified="2024-05-29" version="1">MEDIKLNDSFTNSAIKLNESLTRLNKDDHDASKYNFEKLEKEFKLKEEEWQKERLANDSMLQKKNEQIDTMRVKLNRYEFAIKEALLFLAKPMESYTAWLQNDPSKSINFRDRNPSEPKKLVAVASPQQAAQSQQTKITILTENIEVKPLEELGSPAATYEVSSDISADQISSLECIRLALNYLKSAQSSVQNMGTFKANSAAPKVEDFSNPEKKLDSDYLKDFGKEQENKILSDPISNTTEIVLQEFAERQLIQTQKQIESLARSIKQEEKKSNTVFLEEVGDLALGVQRESLNLPPMKKNETCQNCREYMLRVDHLQDQVDYLKRDVTALVSQLNEERSCRQRVQLSKDILDQELEELTVQLFDQANRMVIDESKLREQFENNNYVLQGELKDLSKKFGNREQELNDLRRCLVALDEAKQRAASGINDSPRSSLTSLSVSPIKSTTLQAAEYFYKSSGNFFSSRIGPQKELLPFIPVDGVLLMEFQEHIKVAMTCQKMTLENQLKLLMETTFVKRSLLEVIEPCLFYSYQHNFTNLKASTVSSSFKKKLLDSVIRSLVEIKLYWSSKEDLYLNNYDVADEARLSNAPDSAVSTASNTSTSATSTPLSQFSSKNPPPLQTNQNENGPPKKKCSNCCMLKECDYRMRFKQPENPKSKVSEWFQMCRFCRDRVASSCDFFTFIINIANLKGVTLLGMFRHMLWLKRKVVVSIVGSCSLFEGEVVSSFKNGEVNSSGWEKLVEVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5S4</accession>
    <name>A0AAD5U5S4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000256">
        <property type="protein sequence ID" value="KAJ3221038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5S4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051144">
        <property type="entry name" value="Formin_homology_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733:SF8">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="844"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="879" mass="98305" checksum="938363A6D44D7BF0" modified="2024-05-29" version="1">MMSDEKVELTKKKSTVTIQRKLTTIQSGPLPVPVTLPVKEDEPNNSQTFTIFLQSSKGAMPIQCPIDADLNWLLQTATIRFSMRGLLCPFVCARTEEGVTLTEFDNLADIQKQHGIFLFTEQETKQMPELAKYFFNPDVLELEEINKTNTDDDYLVPEPAESLKRRTGMKRDSFLTSKSILDKEKDKLGLSSSPSLRDSVLGLHLSETDLSDPDVQRKIEKRKIAFEEIDFEIGPEVTDIPKIVLGESTLHLEQGQHEKTKHDEDTTDDRKPSGFLSELTSVLKIKKPVLPTVKKVLDAEDLEKINLRKSKQRIEHSSLNLNYVTEAEFDDDIDSEETEDNTFEADIEGDIGMKNWNKEMDIIRKKTSNTTKKKTVSHSDTIAITFPKLTNDVTPNSVKGLPPPAPPAPPSTIGGPLPPAPPPGLSGPPPPPPPPGLSGPPPPPPPGLSGPPPPPPPGLNGPPPPPPPPGFNCPPPPVLGAPHPAKPVSSGPVEVSAKDLQNQLALMKKRKLERQKLAAEKAAANLATTEEVGSAAVTDESEKTAELKKLKLAEERQNIIIEVLGYMQASSSGSLEEIIEKANKSTAIARNFIYTLVRKQWVEGFRIIDPSTEPEALNDFQSGSRKKKEKVPCIVYPGKEYSTTITLQDKTIDEINNIYPNQDSFVAEASMYRFDAYLQKHVLDKIKFYKTALFPKPYEAFMEPEPPQDSSLENRNKWEQWNKNKLDHEQSDSAQYNLIYNKLKATDLITVTAFQSLEQTISQMREMNDKVNAAFNDMPITELRKVGFFLTYHKTVNFFQLPALIPREIKNLAARLHKKNGIIIKDEDLKLTPTFLESLMDPDGLTKEERMEKDKKEGLVQERKNKNLASFPRESVDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5T1</accession>
    <name>A0AAD5U5T1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carbonic anhydrase</fullName>
            <ecNumber evidence="2">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002583</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000187">
        <property type="protein sequence ID" value="KAJ3222184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5T1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF265">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042063623" description="carbonic anhydrase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="8">
        <location>
            <begin position="49"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="283" mass="31109" checksum="98A40B557E70EBAD" modified="2024-05-29" version="1">MKTFVILAAALVLDATSHPSFPFHKRNVNCLATTLLNAHTPLQRRSEGLEFSYVGDKNPETWNTLPGAETCKTGKLQSPIDFQTEAMLNPDIPIITWADYTNVEFIHTGNTVEVNLIEGQTEKTTLTYASGNQTFVLNQFHFHDPSEHTFLGRAFPMEAHFVFKTEEAEPKAAVFAVLFQFASGEGSGGLLNQIGASLPAVDKPTTLPELKLKQFGEGLNLSAKNDGVYRYEGSLTTPPCSEGILFNVLKTPTGATAFELAEFYMAMPKNARYTQPLNGRVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Z1</accession>
    <name>A0AAD5U6Z1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Z1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005373">
        <property type="entry name" value="PHAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039156">
        <property type="entry name" value="PHAF1/BROMI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465:SF2">
        <property type="entry name" value="PHAGOSOME ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465">
        <property type="entry name" value="UPF0183 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03676">
        <property type="entry name" value="PHAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="669"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="672"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="689" mass="79233" checksum="28709C854BAF0E2C" modified="2024-05-29" version="1">MNSSNLVSNVFPGEGLTDFRLGTTFQKTLEFIKQNNSFKNVEFLYSDANPLEVDLVLNLNSHGISLKFDSTSQFLRSIEIYSFQNLILSYNGAEFNSQTKVPTFALIYKIFGPIYPGEYQEFKNQIKYVLSYPVNIPVNFADGTTANLERLLIFNKAEGNSELKILNNEKVLVDFEKENLSFLNYKNLPNDINVDLNLISNSAQDILIKFGNPNQIFYKNEERMKIHHSNKNINNSSIDISSGEDYFWNYFELGVDFLFDRKHHFLKKIIFHTNFPGHPNFSRYKRCFFELKLSSANKTASTLDYKSKLESIQEKLGPALGPPIVYNRQPFDISALTNDSEINNCNNDTFFYSAYGNKIQTEDFELKEVDMEETTSYSEHSNNNKNKVDNKYTDCTMNYKPKYSNGVKTGKLKIGNSKNNQFSAKSPSMLSLTLGKITSLFGDVEKALSGRKAFYLERIKHAYKNNNTQLNNESRSIPSRRIILKNQASQKADLLFKEFDKETDVLYNINKDKKIINDSEISKIFENNVNSEDVGNRKRNNSPAPSLLSENSFIDNERIERLEKQVQDLIQRSLSFIPPPPPPPPVGFVIKNHQNTAPSSDISATPINEKKYSEPAHTPKYKMNAMLEEMREVKLRKVDENVLKDRNHLFKENNSNEIFKAIAKKFQNSIQEDSEDECKTDEDEWSLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U718</accession>
    <name>A0AAD5U718_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U718"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424:SF0">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="86" mass="9728" checksum="5D96DDF3EE593C04" modified="2024-05-29" version="1">MADKNNNNTNPETPQELTAFIETVIKQLYQKVNLKVLEKKLTFYLLVDDMGSRIDELEKSIGDLLQQTSADSTDNELEPNTKDPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7E7</accession>
    <name>A0AAD5U7E7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like modifier HUB1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">UBL5</name>
        <name evidence="4" type="ORF">HK099_003331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7E7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01791">
        <property type="entry name" value="Ubl_UBL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000052">
        <property type="entry name" value="Ubiquitin-like protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039732">
        <property type="entry name" value="Hub1/Ubl5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13042">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="73" mass="8328" checksum="B5C9D23598322454" modified="2024-05-29" version="1">MLEVICNDRTGKKVRVKCNGDDTIGDLKKLISAQIGTKAEKIVLKKSYNIFKDHITIDDYEISDGMSLELYYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7H5</accession>
    <name>A0AAD5U7H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Domain of unknown function at the cortex 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000109">
        <property type="protein sequence ID" value="KAJ3224015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7H5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013897">
        <property type="entry name" value="Duc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826:SF2">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08588">
        <property type="entry name" value="Duc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Domain of unknown function at the cortex 1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="225" mass="26017" checksum="CDB1FF34A7390710" modified="2024-05-29" version="1">MSPLFCSMNTIGIFKADSFEVNDTEIQSGKLISKSPSHTIKDDKINALPKTNIVPENVSLLINESQVLNTKSDDESGTKFSLTSNYLTKKKVVSDINIKKNFETFEKRKKFFTDVNNRKKFNISTDHIYCMEYYDAYFDINTISLKLPGVTLNGFRYWEGQPLRYVARSRSDPSIVFFTCWFELIEKSTLLEEEKSLKKDNDKANGEKEKKNNVDSEEEFFDAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7K6</accession>
    <name>A0AAD5U7K6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL30</name>
        <name evidence="5" type="ORF">HK099_001417</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000014">
        <property type="protein sequence ID" value="KAJ3227568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7K6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000001">
        <property type="entry name" value="60S ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00481">
        <property type="entry name" value="Ribosomal_eL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000231">
        <property type="entry name" value="Ribosomal_eL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039109">
        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00709">
        <property type="entry name" value="RIBOSOMAL_L30E_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00993">
        <property type="entry name" value="RIBOSOMAL_L30E_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="4">
        <location>
            <begin position="15"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="112" mass="12205" checksum="EA6951909C271FA8" modified="2024-05-29" version="1">MAPVGKKAKKSTSENINSRLALVMKSGKYHLGYKSTLKTLRQGKSKLIIISGNCPPLRKSELEYYAMLSKTGVHHYSGNNIDLGTACGKYFRVGSLSIVDPGDSDIIAKQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7P6</accession>
    <name>A0AAD5U7P6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase II-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000797</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7P6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039913">
        <property type="entry name" value="RPAP1/Rba50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013929">
        <property type="entry name" value="RPAP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057989">
        <property type="entry name" value="TPR_RPAP1/MINIYO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483:SF18">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08620">
        <property type="entry name" value="RPAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25766">
        <property type="entry name" value="TPR_RPAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RPAP1 C-terminal" evidence="1">
        <location>
            <begin position="240"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="RPAP1/MINIYO-like TPR repeats" evidence="2">
        <location>
            <begin position="1008"/>
            <end position="1127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1273" mass="147777" checksum="8B9D66D76940E335" modified="2024-05-29" version="1">MSDEIKLLKRPSKNDNFDDILQQHQQYINSGVKPSATVISKKSVDNRRKERSVNAELPKKESLFKQRSNKLKSGEKFEVSNQNLVLKDVVKENVVAMENIKDVNFSSNEILTKGGFPPTFHRSDESNVLFSKKILKNDEELKHGNFSSFRNFQGTELEREIHDENFKLFTKLSPKEIEEERHLDQSLDDGAQGKKKKILDNNKIFKSKPVSLEEKKLEWINTPSSLEAPSIKDQPKVAEFRFDFKGLILKEGCDSFDNSLYHHGDQQQNPGYTIQEALYFTRSKLDGQRLIGLKILGEILYNLRETDLYKGDGVDIEYWLYQLNFLVYIRWSRSALVDSNMQVVRLALQILHVFFNVQQSEVFGNLFDTKLGLKRFCLSVESVKGFRNQSLGLVIQKVEDNDVVSVNDNSTMEAVVKLMREDIFKGLLKMNVLDQMTYFLEKNIERTICFELLTIFSMHSVEVSDTLITNGFLKIFLEILAVNWPLEKPTEASLIFLKQLMHSSRKNCDAVLKAGLVDCIMRFVTKPLPEDDQIYIWRLRKQCFCCLRVLWSFKLGIRIFDEYATLIFESFILNKTEKNLIVYMSPWIRMVLSLINFEDFQFEFHFKYIFNEIIKFFQSDTFLHCTESIGQNDLGFYELCSSIVEFLTNFIVNLNKNEKSKITFYINSIAKLKLHQSTFFKSTLNLLTIESTSEKNEKGAYYRYPSFLENSIIGLGNFKAIANATILLNLTCKCNFVSSIIDAFRSFSIIDDTSEWSEILHLTLTSDTVICLLNRGVEKGYWGFHYGIERSNFLRFFGYGWNEFQRIWLEAVGATTPVHAIYDFEPVPLLPYMKTVLLNKSQLSNLAPLIFKVGLNLLTDLLPGDEVVGLKVLNTLIFGESWMKMTLGLDQTEDRRTWKSECFYQLKTCNNLIDFTWDLSKVGKITFPLPLNWIFSPIKVVADQMKLYSNAENGDDSDVKDIDLVLLNLRVLYCIETKIDEGYEGNGKKFCRYPFLKISDEPQLFGLGNKILNIFELFLSGEKVFLDKQFITLTKSLLVMYFKRVIIDDKTSLEIFGRKFSLLMEQSVGGQMKFFKFYKEALEIYASESYCDETFTKLILLPIQMGFSSDYRELFFNSLVDSFKTVKNFEPFHFGDKNGLKPYFFPTESHFGTLTLMLKCLIEIEPLFGLGNSFLQNFCSYHLSSFLFRDLHTMVKGASKNLFQKVSKINFFDERRKLLLGLKAVEKVFEKILWFDFAHCFENLVNGADEFCTTNENYNARKNFCEIILLEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7S0</accession>
    <name>A0AAD5U7S0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7S0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="216"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="545" mass="62409" checksum="C43784292433F60E" modified="2024-05-29" version="1">MNTPRKRRRGYDYEEEYLDDEMQVDKGKKDLLKTVNDLTISELEEAKMIAAEKLRRVLFVDIDVYSEIENSKFSYEAESSFLCGHGNNSKDIIFPSYPMRDNTQLMDIENNCINFVAEASTRSQEHQKKQQNKIQENHQPQQNRLTRSSHNLNTVYASTDQNSFSTSSLFPINKNVEFTFTIKSKIKNTIFGENFSEVGRPKSQKEINKNVPQELSHLKIYVKAFDNLLIPKEIYYLTNFLLKYGLGKLQGLFEEKGDYEKKKKMAEKIREIGANLVVELLNESDCIELSWILLEILDNCKYPVIPEHLHIIFKGILALNNSSKSKRIPSASVLEPTLNIIKLLRDTMLLFPLKNRQLLQWLVGFLCRLSSTSVAKGFSAAAKQLAQVWGPLLTKKSCSTSTDWSTSLIELLIHAHGLCEAVETDSVLWKINSTFEAEINERLSAIKTPRRTTNHFNMSSPRKTRARSGVGSSLKKKIFINSPKKTPQKSSSRLSKNENMETEVNHELQVSVNSSPNYVLRANSPHIQNKSITRENGSKRLRTNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7V5</accession>
    <name>A0AAD5U7V5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phosphatidyl-N-methylethanolamine N-methyltransferase</fullName>
            <ecNumber evidence="13">2.1.1.71</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phospholipid methyltransferase</fullName>
            <shortName evidence="13">PLMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_008312</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32739"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64572"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32735"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64572"/>
            <dbReference type="ChEBI" id="CHEBI:64573"/>
            <dbReference type="EC" id="2.1.1.71"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="13">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Endoplasmic reticulum membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Mitochondrion membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.71" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7V5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000773">
        <property type="term" value="F:phosphatidyl-N-methylethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03216">
        <property type="entry name" value="PLMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024960">
        <property type="entry name" value="PEMT/MFAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15458">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15458:SF11">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11 13" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="12 13" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Lumenal" evidence="13">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="13">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="13">
        <location>
            <begin position="170"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="13">
        <location>
            <begin position="235"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="236"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3227902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="263" mass="29926" checksum="CFC2CA372B5F92CA" modified="2024-05-29" version="1">MEAAQEYVSIVKQVVSSNVMPAIQPHLDGLVELTSPLHPYYLELLTIISPLIIFIKDLENALPNFESFQPKLISIFFIVFHVLFYNSIARLEFNTKIFTKIFGRSAVYVNALLLILSALIRDHYVMRTILLDAGSKPFFDLETSYFIGSTLCYLGIFLNLWTLYTLGFIGMYNGDSFGYLMDAPVSGGPYVMFDDPQYFGTTMVLLGYAIINQSRLGYGLAGVLYIVFHLSVSILEGPHMEKGKFLFVHDHNEKTIKWLKDHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Y3</accession>
    <name>A0AAD5U7Y3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000089">
        <property type="protein sequence ID" value="KAJ3224565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Y3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24178:SF41">
        <property type="entry name" value="ANKYRIN-2 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24178">
        <property type="entry name" value="MOLTING PROTEIN MLT-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="92"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="20147" checksum="EE33C411E4869E3B" modified="2024-05-29" version="1">MTLPIEENELSEEFIEEVLLCSRYNELDELEEMLKNFDFTKNFLQLKSKSNNSTPLHFAAANGNNSILNFFLKHLSINHLKIAGDNLETSDYGNTPLHFASLNGNLESLKILLQFGFDPKVKNNLGKTCSTLAEQQGHHDCVNLILKHWDDEDEDEKNLDIRNEEELEKQRNLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U812</accession>
    <name>A0AAD5U812_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007834</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U812"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01876">
        <property type="entry name" value="PsiMP_glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="Indigoidine synthase A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="9">
        <location>
            <begin position="340"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="722"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="722"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="769" mass="83678" checksum="A1C5A4C74E83F3AD" modified="2024-05-29" version="1">MSRISKLLQNKLLDIQPFIKEALLNNQPVVALESTIISHGMPYPQNVETAIMVENIVKKHGSIPATIALMNGKIKIGLSESDLTLLGKTGQEARKTSRRDFAEVLSQKLIGATTVSGTMIAAEKAGIKIFVTGGIGGVHRGAISSMDISADLTELGRTPVAVVCAGAKSILDIGLTLEYLETQGVSVTTLGETNDFPAFYFPKSGFQSPSHFTTHKQCAELISANANLNLNSGMVFAVPIPEENSPHFTVDNVEQEILRAIRESSYMGIKGKDTTPYLLEKLNEITGGESLKANIALIKNNAIAGSKIAVEFSKLNRNDMQDYSSTSNTDAQLTSNKSPMVIGATVIDLTSKVSLNIGCEKYKLSELLYTSTPGKTTKTLGGVGKNIAEACLKSGGNPFFFSLIGKDDVDYIRNHLKLTGFNCNLVKVSEGEHSSATYNSILGPDGSLICAVADMDINNKICGAEASQKISELKPNIVALDGNLTENCLKNCLETCFSSKIHVLFEPTSVPKSVKIVNAYSDLKAHKKNKIFLCTPNIFELKEMANAVKKASSGDSFDNMTVLDVVDDNKFSGFVSNDAKILILQLILKCGSHGVILFERIEKTENLAKGNSVRVKHYKPRKVLTECVSVNGAGDTMVGVILTGISNFLNVGEKIDFDRLIQSGMDASTLTLLSQLAVSEKLNRANIDCLADFQNQLKYNLNETQLESESINKLISILKQTLSTNKRPRTPHNTPENSDEEIDEKLKLKIRYKNCSKRSFKKLKLNTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U980</accession>
    <name>A0AAD5U980_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">RAC-alpha serine/threonine-protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AKT1</name>
        <name evidence="14" type="ORF">HK099_007342</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000070">
        <property type="protein sequence ID" value="KAJ3225137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21989">
        <property type="entry name" value="RA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ras-associating" evidence="12">
        <location>
            <begin position="667"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="868"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="1037"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="1292"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="120"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="1066"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1343" mass="152653" checksum="7559FA0CB2AD6ADA" modified="2024-05-29" version="1">MSTEDSTLNKNSNGYNGEKLNPNSSLLSPKLQNSNNGIKKSFSFNNLTSNAFLGKKPSSTQVDAEKQTIPNKLTDKKINGPPEFSISTDEKEFNTILPWENFIPKQSNNDSYIVQNANSNSLNLPTAQPNNRRKSFSNMMDNIKSPRSSKREEAKQSDGVSRRSSITKNFFQSRMSSSSGEEDFKTSKTNKKFPPEFSVNIIISEPKDVAHFKTNSEETKRNSSTNSFIGQEDYILPANGFSLKVSSSHQVLMKDEEEFKEAALVCLTNSEMSSVRRKHRSMAYFKARTVGSCTVHFYTVNGTCHKLEVTPNTTLHEVRLEVESTYGNVSVIEDCKIVKLEPNGTESTVNPNTPLDFYIPNDETDIEKLNNAAGILSFKLKSKPPQWNITVEVNSEKKNRFVVVSSGTTGKEVLDLLHSIEGCSDEDRERLGLYRESNRESDAKRNSRFLELDEKPFVMNEDAKYILMDYNDANKRATKLTNIFGVSSNTNINDVISQELNAAEDTKRRNEALKSTKLTHWFGFNVEEEKRTKNRSTSEINNASVTSHLLGRFKKDQQFSVDSSFSTYNSHLGSDECLKRDNQRELPPIAQSTFSLNRQKRFEGIDNNSISSNLSLNSAVASSGKERKTNKLLDYFGVKAGEKDMTVVANLSREKVGRRIQKHHSDNTFLVRVYFGNLTYTSISLPMNATAELAMNLLFKKFNIKDNVELYGIHEYVPNTGVEKEIGKSQQIFDIMIKWEQTEMFLFKRKATKKRLRAQVLGSNSKLCDKDYQIEGEEKDISVIDLSDSLDASKRATKLTNFFGVNDKASSTIQRPFKSFRGKREAEELNKIIREMQTGLEAHVDSVVNQDSEVKAQSASRGVIQVEAISKEGWLNKEEKKVWKTCWVSINSGKLSVRYTNLKRDSVSERDTKKSDSKVIVIPLEESVVEKFQTHQNVKMYTFVILDKKKEKNTFAANSEKECDEWVTAINHARESFIKKIEERIQKRRTQTNLMELPQNLIVPGSLSKHTSIVSSTLDEGLLTEEIEEPSLSLTDFQIHKVVGKGKFAKVLLCSQKTTGKVYAMKVIQKEGENETTDACNESRILHSIIHPFIVCLLCAFQSPERLYLVMEYVNGGELFFHISNFGRFSEERVKFYSAEILLGVECLHGKGIIYRDLKLENILLSKDGHIKITDFGLSKREEDKEEDSSHVVGTLEYLAPEVLKGEKATYAADWWAYGVVLFEMLCGYHPFYSEEREYIHEFILNAPIEFPEHVSDEACDLAFKLLTRNPEKRLGSGGSGGLEIRSQKYFESIDFVKLFNKEIPVPFQPELVDDFDVRFFDEQFTEEPITPVMSSENVHLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9I8</accession>
    <name>A0AAD5U9I8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calcium/calmodulin-dependent protein kinase type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CAMK1</name>
        <name evidence="7" type="ORF">HK099_004601</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9I8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="212"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3226574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="42823" checksum="84FFF91F49A92CE8" modified="2024-05-29" version="1">MTLMDKIKRKIGPEPESAIRRKLYQTLKVLGQGSFGIVKEAIEISTNKHVAMKSILKKNTDSNAAAVAMRDCTKIIYSILDALSFLHHHDIVHRDLKPENILLKNKSDDLKIVIADFGVSNFIEDDEVLNTLCGSPGYAAPELHPFYYTNDLPELLECISNARYTFESPYWDHISQEAKDFITCLLKVDPSRRPTAQLAKCHKWLVKYNPKAKENVDKIKNLLREKKALQEKQLEEEKQKYLEVQEAPLLASSTSVSNLSDLPTQEDEIEELLSKPVVKSVEAIEADAELPNLVKDWDTDGEKSNLNPFNAKVTFKRAISLVKTAARLGSVKRLNSQKECDRSLKESHEILHSELDLKVDDVVEDSSISEIDEKLKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAB6</accession>
    <name>A0AAD5UAB6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAB6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="242" mass="27604" checksum="C39850963996956A" modified="2024-05-29" version="1">MGCGASKDSVAVEPTTSAQPTMTEKKTSQADNLNAQQQEAPQEAAQKQQQAAEEQATPAEKNSTAPARSIEELRKSQASKKSQHTLKQVADQPSNQQLNKQASQQQQQEVQQEVQQEVQVQQEVQQEAQQEAQQEAQQEAQQETQQEGQQDQLEYQQEKQQEQQQNEDSQEQQHEQQEEQQTEQQNEEAQQHEEQQVEQHEQQQEEAHHSAENDQNDNQATQQEQSSEAEILEQQNSEEAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAH4</accession>
    <name>A0AAD5UAH4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">p22-phox</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the p22phox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAH4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007732">
        <property type="entry name" value="Cyt_b558_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15168">
        <property type="entry name" value="CYTOCHROME B-245 LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15168:SF0">
        <property type="entry name" value="CYTOCHROME B-245 LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05038">
        <property type="entry name" value="Cytochrom_B558a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="129" mass="14245" checksum="527822F4A67DA113" modified="2024-05-29" version="1">MSKQLGKNSRFLWGGWASNQSCSSNFFILTGGLISLWYPNTLMPSLPVNISAIINIIIPIIFLLLEYQKIKLGVLSTNYYIRSFLLSLGIAPALLNAPTMTGAMCQFFAVLTYLRAAINGEDGNPPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAV6</accession>
    <name>A0AAD5UAV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003754</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000025">
        <property type="protein sequence ID" value="KAJ3226962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAV6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF52">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN GNT13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3226962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="51530" checksum="C5354E430B39BDEF" modified="2024-05-29" version="1">MTFAYLLRFVSSSFLFETENFQPKYNRVVFPSIVKDLDLYQFFAANFDDSLLNGNISYQFKQSDDGGYVGKTIEYPTINSYLVINEENVVNNDITIITQISVNRLNLLYDIAASWGGSISCVLFVENFSELLNLNENLKLFEMNMKSDPYKKSKLILSLLFGIEFMVDHVTPSIHHPYDFLYPINALRNVALKNAKTDYIFSLDADFLPSKGSFEFLTNDLYYKKLKTLSAMNKGYTAFAFAAFELLTVNFRVPFNREDLDKLCSEVKAIPFHSKISIAKENLNFAKVKRWCQGDILNYHTKVTDIQFLTNFTRWFKAMDIYPIEKDKTQLDRYYEPYFIALKSHIPLFDERFRGYSFNKRQHNIALQYLNYDFLVLPEVFVIHRWHIISSSKKRLNGLVKSTVGRVYNAFLTEMYNKYSKNSEFFPIKKNPLYFQNFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC07</accession>
    <name>A0AAD5UC07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC07"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00083">
        <property type="entry name" value="bHLH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="1">
        <location>
            <begin position="184"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="262" mass="30522" checksum="05DA7A2E9E397422" modified="2024-05-29" version="1">MKNHYNVKEDGTYAVSSSETALNVINDKYYFNNPVGYINTQMLPQYLSQDLLQPSTMQEKIKHLNPLEIEELKLKKEEIELQLKLQQNLQNQNNLKKMIFENKEKDMKGVFSDFNFSEKNLMDQTIDQPLTASLFFNYDQKIVADEAVNFSSAVSDESEGVAEGNIKLFDEMNVINNYKKNGETKVESSKEAERIRRENLRGGFEELRQVLTIKDNKHFSKQQLLMHACKEINEIKKKELETFTLIKNLRKEFNAKKCSVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSQ6</accession>
    <name>A0AAD5XSQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alginate lyase 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000702</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001176">
        <property type="protein sequence ID" value="KAJ3205780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSQ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041901113" description="Alginate lyase 2 domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase 2" evidence="3">
        <location>
            <begin position="220"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3205780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="448" mass="48920" checksum="0014CA3FC2A9277E" modified="2024-05-29" version="1" fragment="single">MLFYTNVTVILLLSTLFNLQSLVRSKPITPVWVLKCSSNTNPPRVGDKLSCYFDSQTYSSKKKNTIAIYQNNVLKVQSQQLSTQKGNYEFTSTDNLSKGPVEFRFLSFKKKSQATFTSIVLQEKLIPTKATSFTNSKSTTTSRSTTSTSKFTASTTNSVSTTNSVYSSSNPATTSTSSTSTSSTSSTTSTTSTSTSTTTSNISATSTTSASSTTIPTASFSLSKFKLQLPVGPSSDKILEISNSKLSSYSSEFFFLNQEKTAYVFHTPVWPEKTNDLVPARTSGTKTTRTELREYPAEWSYDSGTHFMSLTQAVTKAPQKDEAQNSKANQIIIGQVLCGSNPTLNIRYYTGNRIVAMLNDVNDEVPLNLVTNYVLGTRFTIDIVISNGLATVSYNGVKKVTNLGINTDFSRTNCYFKAGAYSQVTPITSGSDSNNINSQYSEVLLYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSU3</accession>
    <name>A0AAD5XSU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cation-transporting P-type ATPase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000468</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001102">
        <property type="protein sequence ID" value="KAJ3206737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSU3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="506"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="551"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="643"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="9">
        <location>
            <begin position="503"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3206737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="671" mass="73803" checksum="F5716989A088EBC1" modified="2024-05-29" version="1" fragment="single">MYLCFASACVLAIIVFGANQFHFSNETLLYAVAVSVAIIPEVLPAVIVLTMALGVKTMAKQKAIVRKLVALEALGQVTNVCSDKTGTLTEGKMVAKCLWVGKTKYKITGKGIEPLGDIFRQPEDFKICSEEISNFTALYQALVTCSMCTTSTLYYCEESKTWKANGSPTEVALQVLAKKVNVMKQNFSDSTFLAEFPFDSQLKRMTVSTVDKEGNVHSFSKGALEQILEISTSYFDNEGNVIELTEEFRKETEEVMVEMASNGWRVLAIAQKIEADSKIFNTFDSVSTNLNTPNRSQVENEMTFIGLVAVYDPPRAESKPSVLLCHNAGIVVHMATGDHIKTAEAIAIEVGIIKPDETGKGDLVIEANKFDNMADEEIDALPELPRVLARCSPSTKVKMIDALHRRDKFVCMTGDGVNDAPAVKNSDIGIAMGLGGSDVTKQASAITLTDDNFETILVAIKEGRRIFANTGKITLHLLSGNVSEVICLVFGLAIQDNLRESVFPMSAIQILWLNMITSSPVALSLGMEKASKDLMTQRPRNKNEGLWSKELILDTMFYGIVIGIMSLSCFLIGILVGRPNLGFVNIPHGCNHEFLPECHYIFKARALTFYCHSFLLLLHGYVCRNSREPFFSKKLFSNKYLNISCAIGLCLVVPTAYLGFVSPLLFTQTAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT49</accession>
    <name>A0AAD5XT49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 5A-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">EIF5</name>
        <name evidence="7" type="ORF">HK099_008358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000907">
        <property type="protein sequence ID" value="KAJ3210093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT49"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="6">
        <location>
            <begin position="190"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3210093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="347" mass="39282" checksum="C20E61400A546944" modified="2024-05-29" version="1">MPKLIAKIEGRGNGIKTVIVNMSNISRALMRPPAYATKFFGIELGVQSNCDDKVDKYLINGAHEQEKLAEVLDLFIKKYVLCSGCLNPETDFIIEKKKKSFDIKTDCKACVKDETNDDNAEGEEDGEQDGDDALTKQIFEEAERLKDIKLEKSGQGDEQDWAVDMSEEAVAARQKELSSAVIEKMMATEDEPEKDPLDIFAEFVSADPRPSDEAIREEANRLEIRDDKAVAILFQILFEKKLDAKVVKKNKSLLSLFLTSEKCQLGFLGGFERIVGQVLTDLLNEKDIPLLLKLFYDEDLVEEESFLAWSEKSSKKYVKKSLNKEIRDKAVPFINWLKEASEDEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTK3</accession>
    <name>A0AAD5XTK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000770">
        <property type="protein sequence ID" value="KAJ3212636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTK3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="21134" checksum="C9608638F7205FDA" modified="2024-05-29" version="1">MGRAKSLKKSLSKCSTKAINPTRNHNVNPARNHCINASGINPINSVLHHSTNPTLNLPLNPINHSNNSSLNHPINPTLKNLNNTVTSNSAPSDSVDSTSIFANNHQTLKSYLSHFNLESMITQPDNGYDNLDFEDEPYHPSSYDNDQQAIQILQRNDKLLDQEIDDAFQSLLSQQSPVCSHTSQPLQNSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUV8</accession>
    <name>A0AAD5XUV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ras guanine nucleotide exchange factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000434">
        <property type="protein sequence ID" value="KAJ3217300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUV8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056685">
        <property type="entry name" value="DUF7783"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019804">
        <property type="entry name" value="Ras_G-nucl-exch_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25006">
        <property type="entry name" value="DUF7783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00720">
        <property type="entry name" value="RASGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="4">
        <location>
            <begin position="343"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="3">
        <location>
            <begin position="506"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="779" mass="88369" checksum="8474AF868DC11E93" modified="2024-05-29" version="1">MPISDSNDKNINVTSQAKEESAEKFWSLLLENVTSAVHDLEVSIETNQNKDILLQQLLTIIEKIRILVVASNTLEILDFKVNHRQILNSISSLIQCTKVASDLKTLENIGAVQKCCHEVSLANKHFVVAAKEFGANLMNLDLIDFTEKFPKPNFLKNFSDLESLSESDFFDLFNGETLHFDQEFINLLDKSRKSLIRSISLLVKTIRLNKCNSNTLISEVRSLVIDVGNYLASVDEIPISSLLDDISMDFKVNRITLYNNLASLVNATQQATSPLCPINSLEYVILNLGLVERSIKDLFVSTKFLLEEKGTLSNEDNTSISKENLKNKSLADDNDGLELVFGSDLSVKGGTLKGLLNYLLNDSISGSNFESQFLLTYRTFTTSTILYEHLRQFFVENVNTKKLTSELVRVRVLEVLELWVENYSEETEEDTKILNEILHLCQSKFLEHQKVKNAVDKLIQTVEEKKKGRLSKSFSSNSVFFLKFSLNSPPPILPKNLLKISLLDIDPLELARQLTILESHDFISIKPFEFLNKEWSNKNSMEISNIKNAAKTFNMIMRWVAETVLNATEIKLRAAYIKQFILTAERCRTLNNFNTLMSLLAGLNSAPVHRLRRTFDQLSSKTKAILDSIGTLMSTTKNYSAYRETLHHLQNSASSSAGIIPFLGCHLTDLTFIEDGNPQFLKINNNQNHQQNKNKIINFSKRIRTSEVIKLILNCQRRIYNLTPIVEIQNFLKEKLTAGEEADGGGLDETRIYELSLSLEPRERDDEKIARLLAESGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUW9</accession>
    <name>A0AAD5XUW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar protease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PEP2_7</name>
        <name evidence="8" type="ORF">HK099_005470</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000428">
        <property type="protein sequence ID" value="KAJ3217429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUW9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="7">
        <location>
            <begin position="1"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="248"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3217429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="442" mass="49909" checksum="7E6F6FA38A38137D" modified="2024-05-29" version="1" fragment="single">EIEIGTPQQSFQFLFDTGSFSTWVRSTKCKNCGTSTDNAYNGSASLTYFSYNTSGSNIRYSDGSSISGILMSDVVGFANLTVNLTFTEAETSTTYLDGIMAMGKTSIYSDRSLFFENLIASKKLDSNIFSYWLQENKYWSADKQFGELIFGGVDNTKYTGDINWIELIKSDFYWSISMSEITLNFNSTETTSKIDPYSLNLRAIIDTGASFSYLPLELAKIINEEIGGKFYQTASKSDNSRVVYQLDCKNVKNLPIVKFQFFSKFGELKYLNIKPQQYMVYYSKTVCISAFFGRKEFPDKRVGLLIGNILLMSWYTIFDSENNQIGFANAQLYNKSLEPKLTVITSKTTATKDTMKLSPNVTKYSESIYITSDTTLKSENFVSTNGSFTIISTAKPEISTANLNETSNHTTDYFTKTSDETTISPFNFFFTLVILLNIYFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV32</accession>
    <name>A0AAD5XV32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001360">
        <property type="protein sequence ID" value="KAJ3203936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV32"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="118" mass="13120" checksum="52AAB4BC250E815E" modified="2024-05-29" version="1" fragment="single">NETSEKILNKIDAEILKVQVLTANYNNENEKFQQQLEVAKRDYIGKKAGGAANQTSQGHAEAMKNDDSDEEEDYNEGGFNFVNQELGTSSGMGYSREIGRDPHGHRKATIVRGDKSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVR2</accession>
    <name>A0AAD5XVR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_001991</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001620">
        <property type="protein sequence ID" value="KAJ3202117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVR2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 12" id="KW-0274">FAD</keyword>
    <keyword evidence="5 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="16">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="15">
        <location>
            <begin position="144"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3202117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="65010" checksum="85367CC1626C58A0" modified="2024-05-29" version="1" fragment="single">MGHAILGSVLIIAVFFQAAFGGFTRLGMIREDIRSYKLLKFIHRYNGLAIVTAAIVQVGLGLYILYPYYESRGLEFWILYIAVAGFWVILFFVSEIYYIKNIVGNTVSNEENKKLLGKGEKIPASRLNDLVKYQDKNNLDSEEKVLYTWQEIDEEVKNGRILVVSNGKYIYDASQWITSHPGGKLILYSVAGTDISLDYFYEAGFDASQFAPKQIAPKHRDDRGNIPQSTSLSRPQQAQRRLTLENFKQPIVNLSEKDWALVVRSRRTHIHTKLALERLSLLQVGELKREVDDGYSSNRTLATNGSLIFNPYEYRRYGMTEKVLLTDDGKSNFIFWKLKFTLLYPYDYRENQPTTFSNGEAIQIQVRLPSGKVIDRYYTAISGNIACFDILVKVKVNGEMTPFLNKCRPGERQFKIRGPFGTSLVKAPNQPDNYMPNTLVYIAAGSGLTPFLQILNTMILPLYEPLEVWEAFTPANSDEVPLNAGDYVVSYVITTTRFGRNFKMILINCIQSTSDIVGLELLDAAMITYPNQIEVHHLVSDFDRGIRDGVSGYIRDGKINEVILGEILSSVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVT5</accession>
    <name>A0AAD5XVT5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="2">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">E2 ubiquitin-conjugating enzyme 7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Ubiquitin carrier protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ubiquitin-protein ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">UBE2G2</name>
        <name evidence="13" type="ORF">HK099_004120</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000283">
        <property type="protein sequence ID" value="KAJ3220656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVT5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23796">
        <property type="entry name" value="UBCc_UBE2G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000008">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="12">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00077195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3220656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="154" mass="17004" checksum="4740B0C9A654F1CA" modified="2024-05-29" version="1">MSSRTALKRLMTEYKELTVNAPDGITAGPISGPEDTPYEGGLFTAVIVFPKDYPLSPPTMKFTTDIYHPNVYKDGNVCISILHAPGDDPNQYESASERWSPVQSVEKILLSVVSMLAEPNDESGANIEASKMWRSNRKQFDAIVHDCVKRSLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW55</accession>
    <name>A0AAD5XW55_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_001115</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010001299">
        <property type="protein sequence ID" value="KAJ3204443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW55"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000012">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="11">
        <location>
            <begin position="66"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="11">
        <location>
            <begin position="125"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3204443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="223" mass="24652" checksum="B83FDADED71BE4DD" modified="2024-05-29" version="1">MNSSVLDLLPTPLKKTQSVDSTVSSRSALIRKLKQEDGQCWPSIGSKKRREESDAELEERLAKLSSSVEGLLLHIGEDPTREGLVKTPLRYAKALMDFTNGYEVNLEEIVNGAVFDEDHDEMLEVHIAYIPKGKVIGLSKLARIAEVFSRRLSVQERLTKQIALALEDTLDPIGVAVVIEATHMCMVMRGVGKVGASTVTSCMLGGFRDDPKTRDEFLRLIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWG2</accession>
    <name>A0AAD5XWG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001143">
        <property type="protein sequence ID" value="KAJ3206192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWG2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="630"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3206192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1006" mass="114946" checksum="B861F35477097494" modified="2024-05-29" version="1">MTSQINLNSNHIQGSHTNLTLKDTINDSIVESSEYPQILQAAAITTTANSVYNSSNQHDINSIDRGVSKGTVNKEHQFVSQHLHKSNSFPSNDEQSTKNNDENSYYSLPHDKFSKILSNDAIKNVKSPTQMHSVVFSGYLQKENRRKKFQRRLIRCDGILLVCLSPKKIKLPDGLTMALFNPLTYSAADEFLPMDFLNMLKKLYPTYPAPIIQLMSPLIAAISEEFGDEDEYGIPDSKSKYFLMPKWVIPLSSIKQIRSIVQQPAKEPESKKACSFVVRTSTRDYLLRAEDSKSFFRWTFLLSRLSESYSEELDIDINNNHINDNILKSQHFAKKISVFRDVVNELVFKDLNSTEFILPIITPYFQLYGEDYSKLSLRRVNSNERTIAKRQSSLSVNSFSNHNSNSVPESSRSPQENNKEVPPIPEAVASIHLQDLSRQNSVTSNFKDSSPSFSSLPQQQFLLDQQFRTRSESQSSYKSNISINQASLEGQLFRIPSVDSGYRNIDVPPSSVSISNGTSVSNALARQNVAEIFNEKQEKKNENLAEYTDFQQTYQEKDTVFIQNPEQLYQYQDSFRSNSPYSLSINTLKNIDKVEPLSNEDYHRSLTSSSDKRYRETLSKKNVSDEKNSRFNSLRNSENPQSASNSNVSQNIIQVNRDLLVSNNNSLLDDGSYLKSYLNDYSILDNSDYTNRNFTSPPPQHPTPDVTYDNDEELLDEVSGLSSNFSFCGKHKKNRTSKIINGVPSRLSIEKGYSKAEHRISMVSSVGTFVSVAIPSEMDSAEYFQNSIRNSLSFSGSDNEKEFKFIQSSDNNNQPNNSILLLDTGLLNELQMHWGSKWHDFIHASESIVRLIRRLQGYETSQFIPSFLQAKNITLIKTSIPTFQIFLKFSTSSLPFFFYKFKDYVENYVEDLNYLIVENNLQNKKETTLIFFFKIFEKLKILVRKFECLRNDWDKDVIQNIRKNGKNFVGINFLPENDILLNVGSVGGSLISVVKGIHEIFCMMYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWZ1</accession>
    <name>A0AAD5XWZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006445</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000556">
        <property type="protein sequence ID" value="KAJ3215265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022343">
        <property type="entry name" value="GCR1-cAMP_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05462">
        <property type="entry name" value="Dicty_CAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02001">
        <property type="entry name" value="GCR1CAMPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="54"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="267"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="33899" checksum="307BDAC1EF6F7022" modified="2024-05-29" version="1">MTYLSIPYPPAAVAKGIISLQDNLQRVATFKDQMETLSTALSWPLRVFKSETFCFIQGALIQYFITATALWTAMIATHCLLAVKLRKPMAVAAAENYKWYHLTVWGISLVMTAVPFAVQDYAAKGAIYADAGIWCWIATPYNDYQVALLYGPMWGVFVYTIVAYTYVAFKIVQARKFVLKSSGGAGKASQNSINRFAFKAFLYCCVFLSAWVPGTINRASALLDDNPMHQVYEFYLAQTIVMPLHGFMNSLIFFFFALTGSMGESTNTTSDQKGSTDLHSPRSMSANNKENDNSYELKKVSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWZ6</accession>
    <name>A0AAD5XWZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001794</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000155">
        <property type="protein sequence ID" value="KAJ3222870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWZ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="512"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="255"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="534" mass="61198" checksum="A3F532407235603F" modified="2024-05-29" version="1">MKPRSMEILSSYEGVVEDISKRGIPVTHFTAVDDKTTLVSVNLSAGFHSKFDYGSLQEQWYVEECLTKFLTKKNVSVLRSTTLTNLVDCKTHVQIEISRGDVHSKNFWNETIVAKYVIAADGAKSRIRKLLNLQFPGEMLQNGYVAVHFKEKEDSLRTFSRNGMVLLFLKEGSAFITALPENSWIAAWDLTLEQEKPFLSSENDARGNPIQLKLRFDQYENQRAFGGECSLSFTDSWTRNEYRCIASKSVLLIILGIQDSMNIIWKLSQVILNKCSREILNSYEAERKHVGKAVVDLTTRVQNISAVRNPLLQNFRNFAFSFVTKNDFIIDTIGQTVGETIYSYKGLAEVSVEYFGKPPIFPYLLRRRAQNINRILSTRVRAGDRFRPDIVLGLSETFFSATAGFKILIFVGLKKYSFKPLSENECTEFCKEALEFSDGLVTDFFVVQSERELDHHRLGVLGQCLFLVRPDGYVGFRCEPLKKELLKGYLKKRIFSKRIETSSNFSFNNFDWLHAVFLSVLFCGIGIYIKRKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXA8</accession>
    <name>A0AAD5XXA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000480">
        <property type="protein sequence ID" value="KAJ3216403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXA8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="68" mass="7869" checksum="212FFAC1B26CBADE" modified="2024-05-29" version="1">MKAINGENIGVNYKIFKLVRIETMAANTEIKIVWIKGFNDELPPNKIHRERDTTIYDLTVPSHSLKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXC8</accession>
    <name>A0AAD5XXC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">METTL6</name>
        <name evidence="6" type="ORF">HK099_007712</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000775">
        <property type="protein sequence ID" value="KAJ3212520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXC8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF5">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="5">
        <location>
            <begin position="88"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3212520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="30531" checksum="CA0DC4B3954F8651" modified="2024-05-29" version="1">MQTSLSSHPLLDSNGSVPEEVLNKISTDEKLKPSGFQVQKLKNETRRNWDLFYKRNTTNFYKDRHWLGVEFEELLPSTNLHTQKKVILELGCGVGNFLFPQLQRDENCLIHACDLSERAIEFIKKNDKFDESRCNPFVCDITTDEILNEIEFNSVDIITSIFCLSAIDPTLHNYGYLDEAQLRFKKSNKIEDNFYFRQDGTFSYYFDLSYINNLFKSNDQEVWEELELNYVLKKCSNKKQGKNFDRIFTQAKFRKAFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXQ5</accession>
    <name>A0AAD5XXQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nonribosomal peptide synthetase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NRPS4_1</name>
        <name evidence="5" type="ORF">HK099_000176</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001026">
        <property type="protein sequence ID" value="KAJ3207861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXQ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012728">
        <property type="entry name" value="Pls/PosA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02353">
        <property type="entry name" value="NRPS_term_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845:SF6">
        <property type="entry name" value="BETA-ALANINE-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44845">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="557"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="770"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="808"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="183"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3207861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="985" mass="110972" checksum="67870551496988B2" modified="2024-05-29" version="1" fragment="single">HLMIFRPDLTAEKFYPNPYPQAMPHWSDFSRYPTNAMLYKTGDLVKYTPNGELEYFGRIDCQVKLRGFRVELGEIESVLCDCDNINTAIVHVWTDEDNGQTIQTLCAYIVLDDPSIEFSENQVKEKIAERLATYMIPSIFVMLSANEVPRLPSGKVNRKMLVKPEINLEDSDEDSNGEIEEIQTDNKIQAEIYLIWKKAFSSAVTVGLDSNFFKDLGGHSLLAARTISTMRENPALAKVGVKDLYKYPTIRSLAHFINPDNESTQKIVIEDRDGMIKRFNELPHRSPGASFPLLGGTLVALELIDPFLVFFPVTWPWEIAFFILALIGYTGARIVQVLFCVLIKHVVMFGRYKSGIFPIYGTYYFRWWFVSNLMGTVNLADFHGTPLLSMFYSFFGCRLGKHVHIHTSTLDCMDLLTIDDGACISEGAIILGYEMKGGWIRFAKTHIGKNVTVGTHSVVSPGTILEDDSTLGDFSHAPVGSRIPRGETWIGSPAVKVTDSRADIEDVYYASGVKYFFYCIALFFGWIVMYIYNLLLIAPFFITGYVLIKFNPFGFGWLWPLIIVFPSSTFGVILFCLMGVLLKICTVGKMKPVHVPLISFYYIRKWMFDSMFNGALVGMHTLFATLYLPPWLRMMGAKIAPYTELSFFAPMNCEMMELDEGCFVADGVVTCAPKMSRGMMTTGSLKVGYKSFVGNQSVVPPNTVIESGCLLGVDSVPPFIKNEYIIKDGQTWIGNPPVEIPARDINTEFEGKATYYPSTLQICGRLVWEYFRIVVPIVITNLVAFGEFLFLVIEDDPNFPLTWWMKILAFPILVGFYFIIIALIIIAMKWIFMGRYTDSRAPLYSSWVRRTELCTGIQEQIAGTTFMPLMRGTFLASLFFRLMGSKVGKKVYWDSFDVTEHDLVEIGDEAIIGPNVTLQSHLFEDRVMKCGKVRIGARANLGTRVTVLYDTSIGDDADVGPLSLVMKGEQIAAKTKWAGLPITSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYF8</accession>
    <name>A0AAD5XYF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SAM2</name>
        <name evidence="16" type="ORF">HK099_005050</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="JADGJW010000038">
        <property type="protein sequence ID" value="KAJ3226342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYF8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18079">
        <property type="entry name" value="S-AdoMet_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000001">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000003">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000004">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="S-adenosylmethionine synthetase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine synthetase N-terminal" evidence="13">
        <location>
            <begin position="10"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase central" evidence="14">
        <location>
            <begin position="123"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase C-terminal" evidence="15">
        <location>
            <begin position="245"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3226342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="388" mass="42804" checksum="8F4EAF4A9AB44A9F" modified="2024-05-29" version="1">MPAANEGEVFLFTSESVGEGHPDKICDQVSDAILDACLSQDKFSKVACETATKTGMIMVLGEITTKATLDYQKIIRETLKNIGYDDSDKGFDYKTCNVLVAIEQQSPDIAQGLVQTSQRVEDTGAGDQGIMFGYATDETPELMPLTLMLSHKLNLKMTEYRKNGKLAWLRPDSKTQVTVEYKVIDGVPVPQRVDTVVISVQHSEEISTEDLRVALKEHIVKAVIPAQYLDDKTVYHLQPSGRFIIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDWSKVDRSAAYAARWVAKSLVHAKLCRRVLIQVSYAIGVSEPTSIYVDSYGTSKHSNAELVQIVKNNFDLRPGYIVKELDLWKPNFSETASYGHFGRSQFTWEQPKALKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYN4</accession>
    <name>A0AAD5XYN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GCN5</name>
        <name evidence="9" type="ORF">HK099_004077</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYN4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05509">
        <property type="entry name" value="Bromo_gcn5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 6" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="8">
        <location>
            <begin position="56"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="7">
        <location>
            <begin position="300"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="389" mass="44597" checksum="1D8111015A341123" modified="2024-05-29" version="1">MNPLDLSIVKTEQIKREREEDSTLTKDQNVEIENNLIPTSKRFKKLALEEERDGTIEFQAISNDGTRQNLITLTGLKNIICKQLPAMPKEYISRLVYDRNHYSLALVKKEPFKVLGGICYRPFVNRKFAEIVFLAIDSSEQEKGYGSRLMSHTKDYVRFAHDVHYFLTCADNNAVGYFKKQGFTAEITLDKSVWVGYIKDYEGSTLMQCSMLPRVEYLEAYELIVAQRTAVFKKISQISKSHIIHNGLDCFKQGKTIQPEDIPGVKGAGYTKELSKMVAMSQRKKSPLYRVLKRILDEAREHKSSWPFLEPVSGVPSYYELITHPMDLGTMTKKVENDEYKSVESFQSDLQLIFDNCKKFNAPGTKYNKAALGLEKFCKDKISKLCANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ12</accession>
    <name>A0AAD5XZ12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bacteriophage/plasmid primase P4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000410">
        <property type="protein sequence ID" value="KAJ3217789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ12"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051620">
        <property type="entry name" value="ORF904-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014818">
        <property type="entry name" value="Phage/plasmid_primase_P4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372">
        <property type="entry name" value="ATP BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372:SF2">
        <property type="entry name" value="SF3 HELICASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08706">
        <property type="entry name" value="D5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacteriophage/plasmid primase P4 C-terminal" evidence="2">
        <location>
            <begin position="60"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="410" mass="47819" checksum="FD35B1445881F81F" modified="2024-05-29" version="1" fragment="single">QKQHAQKDNAQTLLNLDRIFTQVQNFYNEKAEKSKYELKLLTNIQNLIIILNGVKLKDDIIKEAKRYYQELGFKSKLNSKAFLVPFLNGVFDLNKKEFRPAIKQDYVNLTFNFDYDPNVFNPKVSTFIEQILSNKKIRDFVLKEFSKCLNGNIPNTKFLIFIGNGANGKSQLLNLMKLTIGEFGEKMESTLLTRKRNNPNETSTEKLKLLNKRFAFLSEPEDGEKFNIGLLKELTGSEEIVARGLYSSPDMKECFIKFYHNEEFYKQSIFRKLKLKTFINTQNQKNTTVIIGDWSKTNMKHQVPTKGKGFREMFKKAGFNVFLCNEFLTSSICPGCKKRSIETFKYRKSPRPWINRFEKVHGLLHCKSEKCQLPDGKNRLWNRDDVATMNIRSVVESYIIDGCRPKHLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ60</accession>
    <name>A0AAD5XZ60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000537">
        <property type="protein sequence ID" value="KAJ3215538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ60"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="126"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="409" mass="47087" checksum="BED51EBAE5EE762D" modified="2024-05-29" version="1">MTTDQDANTNSFINYEFDEFDDDNFEFDAECEKMLDEIEKTHLQLSNKDENQEVMDGELQFQNQHTINSSLVPSNTYPFKQPFSQNSSCSISRTPRYGTVTKIANNKFTYNNVVENSNEPNPLSLLKILKEENDVLKTQNKNKDGEITIVRINLDKKDKEIENLKLKVQQKVEENITSQISLNYDKEKYETEFEKLKSSLKFSENERKKLEQKILRQKKTAENIELNDKSSHISSIKRNFDKSNLNQTKPLKLQPTSNIRFNTIKNFGSTSHISGSNKRKAEQNILEPLVKQHQTLDCIVTRNQFEDNNGIEKKTYKDEGCQVNFIISEQSEINDDTINCDNFDNTTSCDVSEETFNDNMNGANTKNTLDSDASKKNNVNEATISETNSSTVRLEYLNDSGFSDVTEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y054</accession>
    <name>A0AAD5Y054_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004644</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000334">
        <property type="protein sequence ID" value="KAJ3219584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y054"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PROTON/GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865:SF7">
        <property type="entry name" value="PROTON_GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="Proton glutamate symport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0769">Symport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3219584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="442" mass="48139" checksum="057F51222AA5D693" modified="2024-05-29" version="1">MKSTVIRLLRKTNMVFWIIVGVIVGVLFGFFAKEFSKVYMKLLFNSIFLPMVQALITPLIFSTLVVGIASHDDIKTVGRLALKSITYFMTLTIIAIFIGLIFGNIIQPGTGSNLVSSDVKFNSTFPTVQKELEKIIPKSFFKAAAENETLQIVFCSVMFAVAIMLTPSKKAKTVMLEFCESLSLIMFKVTDLVMNFVPIGVAGAIANVIAVNGTAVFGSLIKLIGAVICGLVTFAILLAVILMVLRVNLLKFIRVVKEPVMIAFASASSEAALPLAMERMIEFGKKQHCGKDNLLFLLGVPADIVGFVIPTGYSFNMDGTTLYLGAAAMFLIQAGNITMSMGEQVIMLLMLMLMAKGVAGVPRASLAILSAGVDLWNFPVNGIAAIVAVDFILDMCRTVINLLGNCVASIVVARWEKRYPEYKKEEINLDEETVVVVDEHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0I7</accession>
    <name>A0AAD5Y0I7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Double-strand-break repair protein rad21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAD21</name>
        <name evidence="6" type="ORF">HK099_002959</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000201">
        <property type="protein sequence ID" value="KAJ3221926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0I7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="entry name" value="Structural maintenance of chromosome 1. Chain E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006909">
        <property type="entry name" value="Rad21/Rec8_C_eu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF69">
        <property type="entry name" value="FI11703P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04824">
        <property type="entry name" value="Rad21_Rec8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="5">
        <location>
            <begin position="11"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Rad21/Rec8-like protein C-terminal eukaryotic" evidence="4">
        <location>
            <begin position="578"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="638" mass="73281" checksum="BCFB276E12C2977C" modified="2024-05-29" version="1">MQLQFALNDIKRGSLAKVWLAAHWERKLSKAQFIQTNIQTSIGDYFNFFILNYSKGAILENNAGEMALRLSGQLLLGVVKIYSRKARYLLEDCNEALIKIKMAFRKGGVDLSEENRFAQYNSITVADARTEFDILLPDTMMHETTQSQSTQEIAPSQNVSRPQDITMTSVSKSFLRELSVDLYQNQDILGQRQTEESTWDLNLDEGLLEPLQDESFNKSISLSNEVEVGREAIKEASYSPINNERSLTFEGENKSFLQDFGENENLIDFSFEKIDRSHEVDDVTPNIFNEPAISIEDQNSFDFYEEERSLKELNKVNERKENSRKIVSQRKKKIILDQFIELNSNDIKKGLQNTSDLLVKEQLLPTSRLLRKLLNIEGQGAYNYLYKPYLENIPTKFHVMFKVNKDRNGKVEQEVKNGSKVEVDTEKNYYDQEQVVHPEETSFGKDIPQDNDFLEDAHNSRERSVEELNSFSFGLDAEGEASLENLSSTKILSETVVEDSFPPEKRILRKRAHELIEVEEMDGNNDLIEDQFDFQESNCNTNSQKENELGFSSSTKKVMKVLKDNFNETNEMAGDDGKTLSFMNLTKTSSRSEKVKVFFELLVLKTKDLIDVKQVEAFGDIRILAKHDLSFEFSTVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0J8</accession>
    <name>A0AAD5Y0J8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000074">
        <property type="protein sequence ID" value="KAJ3224986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0J8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="37385" checksum="98A8E7709AC50394" modified="2024-05-29" version="1">MGLTDVLSGTTHKQNSGTPGPIASFIDGQLENLKPTLLPLYQNGIKKFQITVLDRLEDALDGDQKASEPFVDQPGIMDNITHGIQTTADYLNPVVQFRKNLPTLKKEFGEVLERKHAPVAQQFVDISVTQARQFLVEHINLTEIGTGIKGKVSGFFHKLTGHKKHEDHPAAVIDSGAGKTKAVVDEKNENVVIKDKPAERQAAPDETKDDGGMFGFNRIVSTTLDGGIENIKVRVKDQMHDVLYDVEENLYEDMPEGLQSIFDVIFGGNPFDSDLERERSEVDKDSNNPLVQFRRSMRLKLNKLLEEEHINLENQCIHEFKIAIRSQFGLATEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0M1</accession>
    <name>A0AAD5Y0M1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000261">
        <property type="protein sequence ID" value="KAJ3220949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0M1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="44429" checksum="F8FD10FA9D8F7F00" modified="2024-05-29" version="1" fragment="single">MVESYNLIFKVHPNVTFHSDLIDNAKEGPKVLKNHTLSSCLEKCQNTADDTDCDFILFKNNTCTLQKFEKVSNKLGSNIYLSSTTNIQNIDLIPPSKPSPTQERFCLKKRKRERSLTLERNDMHKQNLAPRVTRNNTFIVKNNNDTKVPADEQDIDNFMNKTINSTNEINSIENENNPTLRSQQPLDGFFSTMYLPGMTGTIRTFRKSKTSSSLGRSKNSFSLPRSKRSADTGQLSSSDSSPQKYNTYPPRPVMDRRRSSESSGKLNDTDVHADVLLEYKNMSRSPNNQLKLVHYSESDSNEDHQEKNEKLEKDFENATKYVAIDANFNKTTYFRGSRTSGYFYPNRQSIASTLNRNSSVIAIADSASFEKVNDTSEETKEDSGDPNKDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y128</accession>
    <name>A0AAD5Y128_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protoheme IX farnesyltransferase, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">COX10</name>
        <name evidence="13" type="ORF">HK099_005578</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000044">
        <property type="protein sequence ID" value="KAJ3226109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y128"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000004">
        <property type="entry name" value="Protoheme IX farnesyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448:SF2">
        <property type="entry name" value="PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="865"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="933"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="960"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="984"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1011"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1054"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1112"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3226109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1146" mass="132765" checksum="E24B8597D499EBC5" modified="2024-05-29" version="1">MQKLQIRNLNWKLNNLCNYCIKRNVFATAYDQQIESLIERDCLLWANPKQLWIANITLKESCSNNNISTKKITSYNVFSTIAAKKSLTSKTNFENPQKFFYSVEMSLMKFKTLDREQQVHLVEATYKSILNVYTKRTQSQTYNFHPDSFSEIISKFIFILGHQDRIDLASTILSLYLKDFSKIEDLTISNRPFNTLIEIFSSKHKFEYAMNLYKVMENNFVPFSDASFSAIVINCRKSEVDFALDMLDLMRMKKFYPSKQILNKCISLCLEKAEEDDTYYRKANEILQLFRQLYSSNHVTGLNVGTFLILIPTVKTFESLNDHIIELASSNFLKNFEIQKEIIKCLDRITLTNTEYLNRFFSLLIRLQKGGNIFSVEGFRIGVDILLKRKLYIDATNLISYYEVSEKPETYLDSNTLNLLLSKVISESISLNVKQRIDICWKILGILQSRKSVIPRITFFKLVELMSALKDCRGLNYLFINKYKDFLEKNKLYIPNNIYKINSAVSENVADDKNSVIIQTTLKNILNLNAFTYLTIKERDCELFDEEVLSSYYCGFLTLNEDSNANNRLNYNEHASNTKITIFEIIFCYLTKSEIFNKDQLNRLDFKIENFFNSILTFLIQKKINFKNEYMFIEELNFLMHKYLELSKTLFYLRKKKGVLEKNLGKGNDSKKKKSELKQFGKEEKCNLRNKNFFDLIELLYEEKLKFRFDLIHKFEVCKINQNTEVMRSSIPIARKLSFEKELLKIKYFTLQFKIKLKIENIENNGVENLLENSYSKSRNYFNHDAYLLNCLEELKNTVTKKLFLTNNNKLNESSAIKEGDSKKISLRFKNETENEENLEKSLNFKSPQDISTLKVFFNLSKPKLSALVVLTTMCGLALTPAAFVPTLNVLFFTTIGTSLCVASANCFNQWVEPPFDAQMTRTRNRILVKRSFHPNHAFALGAVSGISGVFSLAYFVNPLTAALGLTNIILYAAVYTPMKRISVYNTHVGAIVGAIPPMMGWTAVTNSVDLGAVVLGAILYCWQFPHFNALSWNLRKDYSKAGYKMMSVLNPSLCTRLSLQYSLLLFPLCFFCNVIGITSSTLFLLDSSLFNGLMLFGAIKFHRNPTEKSARFLFFMSLIHLPVLLGLMIFHKKKDDDDDQIFLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1C2</accession>
    <name>A0AAD5Y1C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_002496</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000183">
        <property type="protein sequence ID" value="KAJ3222264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1C2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000726">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF83">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="269"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="458"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3222264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="902" mass="103669" checksum="A7F533881FA64208" modified="2024-05-29" version="1">MEETMNVEPTEESNNLEMEELDVDLKERDEFANRLKEKDLEKQRKKAADKAAKIDAKNEKRKLLGNDKVEREERLPDLRERSRATYLERREREKLEALELKVLDDEEMFDKGELTKAERREMEKNKKLLALAKERMALNETEEGYHMPDDYITEKGKLDKKKQESLLYKRYEDKSAENETFISEQETWEQEKIEKTLAKVGAKGRENEEFNYEYMFDEDQRINFLLHSATEALLAKNDEPQISEKEKKALTMKQVRDSLPVFEYRQLLLDAIRDHPVVIIVGETGSGKTTQVPQYLYEEGYCKDGKKIGCTQPRRVAAMSVAARVAEEMGVKVGNEVGYSIRFEDCTSEKTRLKYMTDGMLLREFLSEPDLASYSCMIIDEAHERTLHTDILLGLVKDISRFRPDLRLLISSATIQAEKFSAYFDDAPIFNIPGRRYPITLYHTPAPEANYIAAAITTIMQIHITQDKGDILLFLTGQQEIEEVQENLQQICKGLGTKIKELIICPIYSSLPSEMQGKIFEPTPDGARKVVLATNIAETSITIDGIVFVVDPGFQKQKGFNPKTGMESLLIVPCSRASANQRMGRAGRVGPGKCFRLYTAWAFQNELEENTVPEIQISNLSSVVLLLKSLGINDMMNFDFMDAPPAETLIRALEQLYALGALNNRGELTKLGRKMAEFPAEPNLSKTLIAAEKYECTEEIVSIIAMLSVQTGIFYRPKDKQLHADQAKKNFFKPEGDHLMFLAIWTAWVESNYSVQWCYENFIQYRQMKRARDVREQLTRMMDRVEIQMVSNPDPGNTIPIRKALTAGFFFHTASLQKTGDSYRTTKHNQTVVVHPSSSLMNQFPKWVLYHELVFTTKEYMRQVTEIDSSWLLEVAPHYFKKKDLLIDEKKLPKAKGKSVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y220</accession>
    <name>A0AAD5Y220_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="2">
        <location>
            <begin position="1117"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1672" mass="188826" checksum="E47E850702CA1AEA" modified="2024-05-29" version="1">MIFLVKETFLNSIPIRLDFLPKELIPNLSSYLDSYVGDLDISAFIPDMDFSALTNFTAAYIPSLKDKEKSEDFYPGIELKEKFGLKAKHSVVFIPGIVSTGLEVWNAEQKSPHENKRSTTSCGLKYFRKRMWGTINSFRAILLDKECWFEHMRLDSVTGLDPEGVKLRAAQGLDAADYLFPGYWVWARIISNLAVIGYDSNNMFLAAYDWRLSFSNLEIRDLYFTKLKHIIELAFKSGVKEKNGDLPGVLVLTHSMGANVFQYFLSWVTSPVGGNGGADWPDKYLQGWVNIGGPMLGTPKAIPSTVSGEMRDTAQLNEFSSYVLESFFSKKQRSLLWRSWGGIGSLIIRGGSTIWGNETFAPDDLTNSGAYGPILEIAKLIDPPMQAKNKTYLIKKKKITGDKLSKFLNDNLKDIYHRDEYASHIATSQKEIDDSIFNTSFWANPLLSPLPKFGVKSKFSVTCIYGVGSGTERKYYYKDTGKNFDSPDSDEMRYMIDTDVQNPDLNIKNGVLSGNGDATVPLISLGYMCVEGWKRKRYNPSGVPIVTREYKDNSKVSINPFTEGNLRGGPETADHVDIMGNFKVIEDVLKLASGYSLKDKIHSNIKEISKRMTQTNDDTPLSLLPESSTANVKQLNSIDVNVSETEYKSKISNIIATLRTEYIDLTNDLLKNKSLSSRADLLVKKNAQLVTEQELKLEILNTKLNHSIVAADESKKNSIELQRKLDELTTKICEAETEQLEFEESPKLFLSKKRKFVDYIGEFEIGDGNLPRKGSELSGFETENQLFTESFNVNNNSTVENSFDCETKTFNVENDSNSTLNLFSNSEISSKAIEFFKSQANLPALNSESLQHCQQLNVDNFSHLQQRLGMFQRQPAHGKSQKQYQPMSQQQVPLKEKSLDSQNLGFGNQTFWLDKLKEQVNLTSKVQSISPISEEVHAETEVTSKCANHFIPSYPTPPSRHILSVPKGDACVHFQLGNCYSENCHFEHYCVRCTGPHPLFACNSPRYICIKWNMKECGDLNCVREHRCLKCCDKGHFLVNCIAPEKKAPVSAYCKTVNCRRSHACLRCTLPHPSTLCPRNINQYIRELEEKRRAMCPFSHLQNETKFTKEQEHPSLSEDKLECKNFNSINGCKYGNACKFQHNTTASKDQKIDRSEEENEAVCNSKEKKLLESSLKVVITKRVPSENVKNTLLPQIERSAPLKAKREIVKKPVIKLLQEKLMLTKDPIDQAKLKQKIEIGQLEKRFPNNIKVNFNDGIGYEINFTLIPTDPDFPFFLESKGLLVGLFVDTLYPISYTTLKILNKEIPLHLIKNIENTFNLKAARVKMTLLQLINYLDRDLESLLSMPDRKSDMTFISNEKKDGDPSEGAREVASDLLDSASNLNIAVTKATEDTSLDTGVTQKNDLEVKENCSGHKGIQIKFLNVKLENISSLKLQCLNLGVKCVKCKNENIIKNLKSNTSNFFYCTYCGEELGCRFRPVVLDLKSRSVGYLDFVNCTAYQLLPLNFLPTCLNCSNDNKKFFFKDFSVDDICGPNFIFKNCEKCFSKMNLSLSNAKFVNLAPTNLDLHKEYHDADITGLKANKLKKNLDGLVLGVGLPKNGNLIDGSGFLVVLNSLRVWIVTIQIVLAWKVHLLVELFVDIALRNSDMILKTQSAFHALKTLRNPAKKILIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3N4</accession>
    <name>A0AAD5Y3N4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="3496"/>
            <end position="3519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3968"/>
            <end position="3997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="4748"/>
            <end position="4778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3974"/>
            <end position="3983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="3984"/>
            <end position="3993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="5816" mass="662541" checksum="ACCA51F380984627" modified="2024-05-29" version="1">[encoded data, 5816 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3T2</accession>
    <name>A0AAD5Y3T2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000017">
        <property type="protein sequence ID" value="KAJ3227404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3T2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="167" mass="18826" checksum="5C76E08AA68EEA54" modified="2024-05-29" version="1">MGCSQSKSDEVVETTMTSIAKPVVFEKEEEFVEKVESNTVKNPVVDSNRSIPALNHLDPISVKPTVQLSVIGSNSPFQKNILPSISHHKHSDHDELEEIILASQGEEEYAFDPDNDEEPSKLFTKKNSTETFENNILNEVQMSQHSVNDRKQLDNPWIPGMADDDQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSN3</accession>
    <name>A0AAD5TSN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002229">
        <property type="protein sequence ID" value="KAJ3198921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSN3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="57" mass="6697" checksum="19A36918146D186E" modified="2024-05-29" version="1" fragment="single">WKYKIQKSAKKEFSIYNSNSTDLKRLLKTSISKAKVYKLNYLDSLGELSLAKEYFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSW9</accession>
    <name>A0AAD5TSW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Golgi phosphoprotein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOLPH3/VPS74 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002153">
        <property type="protein sequence ID" value="KAJ3199261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSW9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031985">
        <property type="term" value="C:Golgi cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070273">
        <property type="term" value="F:phosphatidylinositol-4-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048194">
        <property type="term" value="P:Golgi vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="entry name" value="yeast vps74-n-term truncation variant domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704:SF2">
        <property type="entry name" value="GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704">
        <property type="entry name" value="TRANS-GOLGI PROTEIN GMX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3199261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="31508" checksum="3DF3614CF3388A99" modified="2024-05-29" version="1" fragment="single">SGLRSEGLKQRRGAGGSQNNSQNDINSSDSQNNNRRSSYDNKGGLTKNDDRDDDNGKESKQNRLTLLDEVFLLGLKDAQVLRGCILMELSLRGRIATVKEVRKRPFADRIVEVIDDKNTGEVILDEALKLIKIDKQTVSSWIDLLSGETWNLMKVGYQLKQVRERIAKGLVDKGVLRTEKRNFVLFDMATHPVANQLVKDQLIQRVVDTLLGRGPPPDSRAIATVCAAYAANVLENALVGLSHTQREAAFTKVDELLLEHSVLGEKAKAIGTSDIMAGVLVVYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTM2</accession>
    <name>A0AAD5TTM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vesicle-mediated ER to Golgi transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">USO1</name>
        <name evidence="5" type="ORF">HK099_001703</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001507">
        <property type="protein sequence ID" value="KAJ3202888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTM2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048211">
        <property type="term" value="P:Golgi vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024095">
        <property type="entry name" value="Vesicle_P115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006953">
        <property type="entry name" value="Vesicle_Uso1_P115_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013:SF0">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04869">
        <property type="entry name" value="Uso1_p115_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vesicle tethering protein Uso1/P115-like head" evidence="4">
        <location>
            <begin position="445"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3202888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="612" mass="68528" checksum="FD31A865CF507105" modified="2024-05-29" version="1" fragment="single">DKGETQDGVEVINKIVDRISNSTLLEDRRASVLTLKGLAKDWKLDVGTKAMNCLINVLKTDRMDVDIINASLETLNFLFSKDDDDNLNNENKDTDLGFMFSEIYIKDPKNVTLLLDILEEQDFYVRFHTVEILQTLLLNMGSKLQDTVMTSPLGISRLIDLLDDHREIVRNEGLLLLISLTHSNAEIQKLIAFEDAFRRLFEITFQVGGAVDGGIIVQDCLQLTLNLLKHNVSNQNFFRETNGIQSLKKLLTKVIYHKDQQFEVFLSHETVEWDDDQKIKNICFVLEIFRNLVGPNSPNTETNQNVIYQSNILNPLINLALSAQIPFPVRSQALFCLGDIIRGNKVSQDAFSKVLFSKSEANSAVPVSSGKRFPSSASQQSLGPVSGKPAIVSIVKAALDKDDFSIRTAATYALQCLVFDNADMQSILASTFTPPPADHTDSEDSAIVLSHIVSENQVAKELCLKVTFGDEGEDEKINLLHKLMYTLNQTSRENAGIQGPDVRIYIGILSFISVWLYDFSVGVKEFFSEGVNLQFLVEQIIQSSGVDPLVQGLSSYLLGLLFEFNDNPKESGLDKQFVQNVIVSRIGSDVFLGRLSRLKESPYFQKANLYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU65</accession>
    <name>A0AAD5TU65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001263">
        <property type="protein sequence ID" value="KAJ3204811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU65"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="73" mass="8031" checksum="04648C39386817C4" modified="2024-05-29" version="1">MSDLKKGKKSIWKIVPDLESLQQFSNRIGISNKLDIKFSKVGLDFLEATMLVSENCIQPRGLLHGGVSCVLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUG7</accession>
    <name>A0AAD5TUG7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000929</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001238">
        <property type="protein sequence ID" value="KAJ3205058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUG7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015218">
        <property type="term" value="F:pyrimidine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990519">
        <property type="term" value="P:pyrimidine nucleotide import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF4">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00784">
        <property type="entry name" value="MTUNCOUPLING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="58"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="189"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3205058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="32419" checksum="33C33E9639085AEA" modified="2024-05-29" version="1">MKGVVNILGTIRREEGIRALWKGLGPNLIGVVPARSIYFATYSQGKHLYSKYLNNGVESSFIHMLSAATAGASVALVTNPIWLVKTRMQLQNESAALDIIRYKNSFHCAYVVFKTEGIRALYKGFSASLVGLSESTLQFVTYEWIKKIQREKREKLFYQQNLKKNNFNNNNNNQEKKNLINPLVFIDSPNWFELFFSAAIAKLGATLITYPHEVLRTRLRQSPDSSGNIKYKGLINSTKLILREEGIAAFYGGMTAHIMRVVPNAAILFFTYEVIVHWWQRKPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUR0</accession>
    <name>A0AAD5TUR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000766</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001195">
        <property type="protein sequence ID" value="KAJ3205547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUR0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055225">
        <property type="entry name" value="DNAJC11-like_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22774">
        <property type="entry name" value="DNAJC11_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="33"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="470"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3205547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="655" mass="73874" checksum="B574AB0CA25D6B6F" modified="2024-05-29" version="1">MNSKDSTESLPIDENIYDDDENEDNLKKIADVNLYAILNLNSDASEEDLKNAYKRSVLLFHPDKHKDSNKINAESKFQKIQYAYDILSDSGKRYIYDLYGHEGISTSWEIGTKFKTKEELREEFERKKRIEKRDEMNNLIKSKGHVNLRVNASSLFAPYDFSEVKFVNNIGYIRKASTLKEENYFLDIYHRLKNVTFKTVTVGHFWEAKLNDKTDLTIGGSAGSGNVSASRSFSTSLRHIHSPLLWGEVSTSVGSDSSVSVKVVRNFSEDSFATVSAATNTTTIPPVLNFTIGRRLSKTFTGYIRYSTGEFSFLGWGNEYVEGSNSSTAIGIVRTIENGATVSANLQAGIISSSVTTSISRNFEELLFFGKNIRLKADFYISTNKANISALGIGVGADKRVGSYGKIGFSVDTSILGITLRLRFIRQGQKLSLPIFLTQDLDLKVALYALIFPIGSLITLDHWILRPARLKRRQEEIKNLKVKNAEELAKRKQEALEAIELMRDSAQRKVEQESSKNVSAQYGLLSEKSSSTQDLFSMNYIKTKFNHLFNNNISEAETSGLGKSTNSLLEEASKDSSSEFVQDVTIVLQSLVQQSQFHLMGGVSKSNLIGFYDPCFWEKNKKLRILYRFKGKLHEVEVNDLEKVRLPLRAHQIME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV97</accession>
    <name>A0AAD5TV97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UBP12</name>
        <name evidence="11" type="ORF">HK099_000471</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010001104">
        <property type="protein sequence ID" value="KAJ3206717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUSP" evidence="10">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="308"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1176"/>
            <end position="1207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3206717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1353" mass="155918" checksum="0C842868812E0464" modified="2024-05-29" version="1">MTVKKKSIFLSSDELIGDEYYYLISQKWSESFSNFQSDEKFSNPGPIDNFSLFRKEDDKLLLKPALWFDKDFKVVDKANWDNLVNKFGVKADHMIKRRAKQYRNNGLNVVEVELYPNEFIDCYFQRVEEKSNLKQNEETNKIENYLFRASLYPNETTVEIVDRIITRLNNADSDTEIKNFKRENITALYSTPKPGSPLTPVSMVFSAVISDFVLSDNNKTIILFKLVTSTELKKAKIKAQHDSYYNDIPISTFNNSTPLLLNNIDIKSPPRNDVDNEEILTPKTQPFNPPSYSIKNYTSKNYSTIGVTGLNNLGNTCFMNSSLQCLSNAAPLTAYFLSKGWESELNPDNPMGAGGKVAEDYAKLIRDLWETGENRPTSVAPRSFKYTMGQFNSMFSGYHQQDSQELLGSLLDGLHEDLNRIKKKPYTEIPDMEGKSDEEIANKMWELYKLRNDSIIVDLFQGEYRSKVVCNTCKRETVTFDPYMFLTLPIPQMKDLAIKIAILPKQGTNKKYSKSGQPFYMGFLLKKEATVLDLKKKAAEDLGWSHYKKGDADVKAVLVEVFQGRIYKLFENHESLDFAKTDIIVLAEVGDDDKLDANEEEVAFNKLLIKDEMHEIDPRLPETPIKTALIPVYLNITGETQYLGLPSFINIPSRIKIKLKKSVRIDNNYLKTKIGNLIYRKVLNSFLKYTKNKIKKLYKRVDEPFEDNYFQNLFEDTMDVDDDDTEEEENLVDPGFGWSPLPNLFNIQMYVGVEERERRFSRFNENPLSSFYNNDFGKCPNIPIYPPQIFSDSTTETNPVNRRTMPSFSTSPNSPPKFSTLQFQDELHNNNIVKNFNIPSDEEELPVQDILLNEAGDLSSSATVVSNVSTHNNDAYVPIIQEVPSDSLKNNYKIIEEEKEGYFTIDFTPMTIFKCIFKKNVANFLFDMEFEKNTYYTPSSFAFNKKNFAIKETEECKNFFFEQERKRMLEKDKKLSLRDCFNEFTKEEELSESDTFYCSRCEVHRTIKKKLDIWTVPEVLVFSLKRFSNTQRASFRSLSEKIDTLVDFPIEGLKLGKDIVLGKKIGTKNTNSSAGGSSSSYNSETPHFSQTAEDDELVYDLFAVSNHMGGTNGGHYTAYAKNALDLNWYCFDDSHVSKADINRIVSTSAYMLFYQKRPINYVKTNKNNLSLQLIIENIQILKRVQLENEAEEEEEEAEGNIQQESTILNSTYPAMPHADIFNFNKFKKQYSDQEESEKQYNFKSLSSSSSTLRTSMMEGEYSVGNFSSIDENIQDVRRDLDNFYDENFRSKQDGLMESKIEFGGMKEEEDNFNVSDSDDDDVDLRLKKTTGVSISNYLKTTEQDEKEVDMWDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVV4</accession>
    <name>A0AAD5TVV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_008602</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000964">
        <property type="protein sequence ID" value="KAJ3209013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVV4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000196">
        <property type="entry name" value="Cell division control 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="6">
        <location>
            <begin position="29"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="293"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="314"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3209013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="965" mass="110793" checksum="BEF1FD78629E4352" modified="2024-05-29" version="1">MTSIISKKLLGPVGFSNLPNQVHKKSLKKGFQFTLMVVGESGLGKSTLVNTLFNTTLYPSKENKEPTTEVPKTVEIQTISADIEENAVKLKLTVIDTPGFGDFVNNEESWRPIFENIEGRYDAYLEQENRVNRKRIVDTRVHACLYFIAPTVHSLKPLDIEFMKRLAHTVNLIPVIAKSDTLTDEEIKIFKNRILEDIAFYKIPIYQPPVHDNDDPETIQENKDIIAKIPFAIVGSDREVEFNGKKVRGRKYPWGVIDVDNEDHCDFVKLRQMLIRTHMEELKEYTNEVLYESFRTQKLAAGALEKTNDGQNPLTKFDEERLAHEQKMAKMQAEMKAVFQQKVAEKESKLKSSEDDLNDRHRIMKEELERKKAELEAKRLKLESGYATKPELILTFQSKLYSTSLFNVTLKQGLFKPVSLFEYSVKDKSADNDCLNNLKNAVQKLKTLRHPRIIKFHKAQIDDSKISVLTEKVEPLCLVLNNLPQEEVCMGLYGILEICHNNLQISSIYISKNKEKKWLLSGMEFVKPVKEMEESFMKNLANNLPKEIIPPEDNDPTLRSKFQDRDYFALGILITHIIEPFIIKSVNTIKNTENQLFKWRQLQTLADGCISMNPLKRYDAEQLLESQFFENNSFIQITEKFLMILMQLTAAEKQEKFLALPSQIRELPMSTVAAYILPLLLTKEMFSEPNVIDIFRELFSCPGDDSILSVEVYQSHIVPFIKEMIKVKTFDVRLTMLKLIEFYFVPVLNYTMGYWMDSVIEVILVGLEDSNDDLYYYSLKSLMFVIPTYIETVILSQNQENGVSLIKSGSAKSIHSDLGNDESVSNSVDELSSRLPITSLKKYSIDVLINRVTIPHMLNIFVSPILGEEKAWGSIESCISMWKTLHLLEKNSPIKSSQLLPIYRSILKSFQLVLKASNEEKKLIFLEKLTGKLSLENEYEFKNSVGASAIYIIELIAPLLNDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW53</accession>
    <name>A0AAD5TW53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rapamycin-insensitive companion of mTOR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000769">
        <property type="protein sequence ID" value="KAJ3212640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW53"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038203">
        <property type="term" value="P:TORC2 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028268">
        <property type="entry name" value="Pianissimo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029453">
        <property type="entry name" value="Rictor_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029452">
        <property type="entry name" value="RICTOR_V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13298">
        <property type="entry name" value="CYTOSOLIC REGULATOR PIANISSIMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13298:SF11">
        <property type="entry name" value="RAPAMYCIN-INSENSITIVE COMPANION OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14663">
        <property type="entry name" value="RasGEF_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14668">
        <property type="entry name" value="RICTOR_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01303">
        <property type="entry name" value="RasGEF_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01310">
        <property type="entry name" value="RICTOR_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rapamycin-insensitive companion of mTOR" evidence="1">
        <location>
            <begin position="206"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="477" mass="54543" checksum="047E0D26308EE994" modified="2024-05-29" version="1">MRLFATSHLRYLLRTGVKDFWEWAIPLLITQLYDPVSLVCERAVSVLDESFDEERNLDAAIKLRPSLNHLGNIGTPILLRFLSTSLGFKYMDEMGYISNECEHWFQFEIINYVSMLENNINLSLARSSSNLKSEGDDMSFSDTVKIENEENDNLGWDLSGTVPPHFFGELTKTDEGCKLLEKKQYFTGFVDFLKSWGLKSCGGVVLKKMKGVLWAIGHIGSTLKGLNFLLKQNVISDILAISQYSSVLSLKGYRLISRTHTGSEILESLGWQAVNRSNGSLDGICIPKDLDKFYNIPVWRFSGSWPDKRIKLKYVQSKFEGPEVEILRLIGSMANHIQAQEASKALQRLRIDSPIHFQKMELYIELMRIVSTSHYRITARRFLQDIFEKTLFNEEGFKKLDDLNGLNYSVKQEHWNKFKQDQDDDEYVELMFNSAIASGNRRGVQNAVVGAVVKMEEKVEKGTDVILKPLKVIKGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW92</accession>
    <name>A0AAD5TW92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000765">
        <property type="protein sequence ID" value="KAJ3212714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW92"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="199" mass="22622" checksum="84F490E68AB0E7BD" modified="2024-05-29" version="1">MGIPIRTNQNGASNTFSSTGAPSTDSLLRAVLNLPHTSDLKDFFEILFSRMSSQSKEGVAEIIWGLNNQASFDFPQRHEATSDNLSFFTDNPNNATSGNRYLPTSRLISSGNSSEGSVNRRQYTGEINVYERDELQRSQRRRLNPNNPQGSTTSETNQNIDGIPTYEQFTRERREARLNAQREILLNTRREFVNRNLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWY4</accession>
    <name>A0AAD5TWY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000702">
        <property type="protein sequence ID" value="KAJ3213509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042195882" evidence="1">
        <location>
            <begin position="18"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="171" mass="18026" checksum="881A998DE651EB96" modified="2024-05-29" version="1">MQFKVLIALAVASLVACAPKPPVQSTCLVARDSTCLVARSTAPIKDCDQCHCLVESAGICLLARSESPIKTDSTCLVARDSTCLTARSMIPSSEGMLVARGEIPEDSTCLVAKDSTCLVARSDIPIKEDSTCLVARDSTCLVARGEDEKILVARSELPVDSTCLTAEDSTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX14</accession>
    <name>A0AAD5TX14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Eukaryotic translation initiation factor 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EIF2C1</name>
        <name evidence="2" type="ORF">HK099_001169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001305">
        <property type="protein sequence ID" value="KAJ3204395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX14"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="1">
        <location>
            <begin position="120"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="363" mass="41472" checksum="EEB8765E0915C3E0" modified="2024-05-29" version="1">MAVLLEYLSPSPKAIEIPFEAVSCLEVLLRQSPGLRFTSNPAGRCFYNDKGVSQLPGGVNVHYGWYQSLRTSLGIQQQQYTYKELLLNIDVVATAFYQQGPLIDVITNFFGKRRIEDCQKLFTIKNELRNRDKFISSLNIKISYRNTGRRKYKVKGLAAQSVRDTKIRIKEDDGVHEVTTTVQECFRKTYNYNVKYPWLPAFVSGANNVQIPIECCVVLPNQPYVKKVSEDQAADMIKVTAVFPQKRKERIQDGLNQLHGNNDEILLARWNVDINQSLKQVEARILDTPSLMFAKNKPQKVFNNGFWKTQGFAKPALLVSWSIALFWGDFGVLDSFMNKLDNELASQVVEVLWPFRINTTSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX43</accession>
    <name>A0AAD5TX43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATPase Cu transporting protein 7B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ATP7B</name>
        <name evidence="5" type="ORF">HK099_008733</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000998">
        <property type="protein sequence ID" value="KAJ3208379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX43"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000043">
        <property type="entry name" value="Copper-transporting ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594:SF4">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00942">
        <property type="entry name" value="CUATPASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="4">
        <location>
            <begin position="258"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="4">
        <location>
            <begin position="338"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="4">
        <location>
            <begin position="426"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3208379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="529" mass="59073" checksum="953514F8878D8E3C" modified="2024-05-29" version="1">MNQKRTSEISFNDHNAIYDAYDTKEDVENSVNLETDFNDNLKHKNTLYRSYGSLIRDGSLNLWFASERSNEKTIKKRERRNTPFLVPPAKISLSNLTPPIRRSSKIHSVCIVTTPPTPDVSAVLITVPTPPPRAYNRGPRAMETVRNDNSTSVTSATVNVSTARTLRNSFEVYGYDKKPTSSHVKQNKKLNYFRFAQSIFSTVTLIISIYLEALVYTSTSTKYFCKYLSASTIIFSSISVATNHFFALSYFKFKHLKNVLIAEVIGMTCQSCVKSIESQLNTLNGLISAKVHLIEENAEIKFDNNLLSQTLILETIENCGFEATLITNENSLTINNTMEITVGIQGMTCQSCVKSIESQLKTLEGLISAKVNLSQENADIKFDTAKLSQSLILETIENCGFETNLSFTMDEPKQNLTKINNNENFIKIILSVKGMTCKSCVSSVTKVLNDFGPLVRNVLVNLQNETAWLEFNTFSLTPTDLKSVIEDAGFECILPSNNLLISSSEVSNTFVNVTVTDISIIGMTCMVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXA7</accession>
    <name>A0AAD5TXA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">N-lysine methyltransferase smyd2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SMYD2</name>
        <name evidence="7" type="ORF">HK099_008556</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000953">
        <property type="protein sequence ID" value="KAJ3209217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXA7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="57"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="144"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3209217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="289" mass="34100" checksum="6842F0CAEE07B9D1" modified="2024-05-29" version="1" fragment="single">MESEKSDLNNIVSGLDLVLEEDEKKYRMLKTRKRITTLERKFVNRSICFANVKSYFCSTCLKSNSNFRCSKCKLKYYCSTECQLMDWKDSHSLLCSEVVDPELEMLVKLKLKDTQDTIYNTLMDHSDSNVPLYKKNQDIFFEKSKLAIKTLKKKKNKNFIFDDKFNFIRDLNIFKFNNFNLTDFQFFSIAEGCFPLGSLFNHSCCPNMFVGYRLDEQSFFSLRDIEIGEELFHTYIDPLIPKEERRNALFEKYNFWCECERCSGNAGNRKDGFHLIDVLIENSGVEEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXG0</accession>
    <name>A0AAD5TXG0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007003</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000644">
        <property type="protein sequence ID" value="KAJ3214167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXG0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF15">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3214167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="125" mass="13474" checksum="393E1E81A6231E7F" modified="2024-05-29" version="1">MVRDFGLGTEEEIGFYVGFIASSFSLAQLMTSILWGWLSDRVGRRPVLLTGLIGNAIATLSFGVSKNLIWAILSRAACGFLNGNIGVAKSVLGEITDKTNQAFGFSLFGLVWGFGMILDRHRAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXP2</accession>
    <name>A0AAD5TXP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL27</name>
        <name evidence="5" type="ORF">HK099_006574</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000578">
        <property type="protein sequence ID" value="KAJ3214995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXP2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018262">
        <property type="entry name" value="Ribosomal_eL27_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01107">
        <property type="entry name" value="RIBOSOMAL_L27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3214995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="131" mass="15139" checksum="6FBFC5FEE3F4DF82" modified="2024-05-29" version="1">MDLFIVVILLQGRYAGKKAVIVKQYDEGTSARPYPHAVVAGIERYPLKITRSMGAKRVAKRSRVKTFVKAVNYNHLMPTRYNIDIELKSVVTAETLKDATQKIAAKRSVKKLFEERYNSGKNKWFFQKLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXX8</accession>
    <name>A0AAD5TXX8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000619">
        <property type="protein sequence ID" value="KAJ3214450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXX8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050789">
        <property type="entry name" value="Diverse_Enzym_Activities"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43283">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="27"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="410" mass="46022" checksum="CC1E450503D9E2F0" modified="2024-05-29" version="1">MLPKVGLIDHERLNAVIPTLYNLNYGAVSVATIQSSKVSFYNTFGLRKYSFFSKSPANTLTRFQAASISKPVTALAVLKLVENGVLDLDKNVNEYLANSGWTLTVSKENKFVDEKNITTIRQLLSHTAGTNASGFGGYNINLSIPSTIEVLRADKPVNSDAIKVTSKPGTFSYSGGGTTVVQFIMETVLEKPFPLIMKQLILDPLDMKNSSFETDRTKGDHLAYAHGYISDPFFLFYGGKNEYHLYPEKAAAGLWTTAEDLCKFGIAVMNSINGKPNAFLNEKLSKNFKTNHNFEKAVDEEGYRDIQKIGLGFFLENCEDELKFNISHGGGNMGFRCFLFLQPHKESGFCVMSNNESNRIGLLCNHLVNNLDLDTDNFKDSTPANNTYMNWLKDYLKNWKFVFKYWMGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY16</accession>
    <name>A0AAD5TY16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Guanine nucleotide-binding protein G(O) subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GNAO1</name>
        <name evidence="12" type="ORF">HK099_006359</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000541">
        <property type="protein sequence ID" value="KAJ3215463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY16"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF362">
        <property type="entry name" value="G PROTEIN ALPHA O SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="220"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="289"/>
            <end position="292"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3215463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="38254" checksum="5B646B98D5E61984" modified="2024-05-29" version="1">MGRKDHNESSFGEMTTDGTGSLVEEDSINLVTALCNNKRRANQRSQQIDKQLNKEKLEQKQFKASELKLLVLGSGDSGKSTLIKQIRLLHSKGFTEKEILIFKEIILENVFDALRNLIAGAKILGTESKTAEYQNDANFISEFKYTKGKAIDNDKILIIFQRLWSDLCIKDCYMRRNEIKQIGIQEYYPTGQDIVCSRQRTTNVNACNLTVNGIRVKIFDVGGQKSLRNYWIPYFDDSKGVLFIVAISGYDQFMEEDKDTNRMIDSLQLFEKIVNNPVFRESAIILMFNKMDLFLEKLRKIKIIDTFPNFVGNQKDLKGKTIKKDIFRIKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY34</accession>
    <name>A0AAD5TY34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008218</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000884">
        <property type="protein sequence ID" value="KAJ3210554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY34"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14810">
        <property type="entry name" value="bZIP_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF10">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="200"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="310"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="403"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3210554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="531" mass="60784" checksum="B798BEAEEACCE5FC" modified="2024-05-29" version="1">MSATEHTNQNFNFENFLNFQQEEEENVGDLSQDDSYELYIPSLNQSDITLTQSQIPSDDNILNLLPPQQADTPSPIEQLSTSSISPFIFPTMKPFFEISQSNTQPLYDWSPSTAIQPPIEQPLNGISPKDIFLSKGSDDDLMSGLESDPEVKIKVEKKCTTTKKSKKQLLNGSVDDLSDLKERSGMIEEQEDFKNEDRNLTSKERRQIRNKISARNFRLRRKEYISTLEDEVRKQRMESKYLKLELEKMSEENYKLKMSFKELKLKFFNLSLEKEEEEKSEMEMKRQAENCFSKIKPSTKLLSQVEIKVEKSDNTGANNENEMNEKNAEKKTSGLRTTSSPKTISVLKVPNPHSSLFQKQALQRKKDLDLILKKFTSTPALEKDSNVAITSNSKVIIPNMTKTSSNTSTVSNSPTRNGIKVPSRIATGSPKFSSNSSPSKSEGGWLHSRVKVHTVFIKENNVPKEILNSFNDLKQNTVCTRGVKMNKKDLKFFENLTIKEKDDVKQFKETLLKKFLFLILISLDVSIKYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYA2</accession>
    <name>A0AAD5TYA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001613</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001476">
        <property type="protein sequence ID" value="KAJ3203106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYA2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF87">
        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3203106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="570" mass="62909" checksum="008BD055520876E1" modified="2024-05-29" version="1">MTDQAEKTASKDNITINNSLQEEDVWVAPSKANTYKIFGLNFVKILAIGIFLHNIFSTLESSMFGTVSTNLHSMLQVLSLNDLPQVSMMISGVLGPAFVRFAEVYGQMPLAFSGVVLTILSYVLFIATGNPGPIVSVNNTPSIVGLGPQSYCFISAQMIHYFAMAFINTMQVILVTVYIPIRLRATFTSVIFLPTLVVQFIGPMLSTFFNNEWRLMFAVVIPPVFLGFLIMYYPLVKVESKFRKKKIKTSFIQFCNELDIVGAILLIVGVCCALTPPMINYADSFTETKNLVPLIIGLLLLILFIPYEYYIAKYPVFNRRLVTNPTVTCCLIVNALGYGASNVVFGNFQALFQITKRLTPSDAAMLQFGYIGGYAVAALICGLLIQYTRKLKIWIWIGYAMYLLAFCLFINTRGSDTSIIEVILVQILAGIGGGISLPAVNISIQAAVKKADVPMAATLLTFTTYLFGPFFGLLASSIWNRYLPVIVASKPGGDSLDLVGIVDTVVDSFKTYTEVQQQIVIDSYLETQRLTTYIGIAMIAIGIIPLYFIKVKNLPAEEQSQESITQENTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYR9</accession>
    <name>A0AAD5TYR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000751">
        <property type="protein sequence ID" value="KAJ3213059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="4"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="218" mass="24388" checksum="79851C1708ED1F8C" modified="2024-05-29" version="1">MSLDYYIVLGVNRNATDSEIKVSFSSFYFDKHPEHLREEASEKFKQVSEAYEILSDKAKRRAYDKYGSSHNFANDNGSFDSNDFFRDAGFSNFHFHDPMDLFSSFFNDPFQTDPFFSGGNRSAANAFQSFSSSGFPNNGGFSQSFFSSSSSSSSPRLSSVSKSTSTRIVNGQVEKVVTTVDAQGNETVEVTRGTQGSQNFQTQVFKNGIEQQHNKMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYY9</accession>
    <name>A0AAD5TYY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005621</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000447">
        <property type="protein sequence ID" value="KAJ3217028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYY9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="114"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="515" mass="58853" checksum="4457324833A8CA5A" modified="2024-05-29" version="1">MSFAMANLIECTLGNPSSNIVSIIENNMSEDTSQDIIQSENEILKVHHNIDNIKRNKDGVDSIAVDKIFPAQDNQKEVDNDLNKKYSSSKEKGEKDANSKTGNYEKNFWKSTRKELTENEEKLHQLNLKKMKEKLTKTVHNLEKKFKLLKNEMKNGPKHEISKKSSKDTKSLGDFRNFIHDVFQDSTEKVSSENGFMDEYYEVTILEDSNIRQAIEKLKANYLKKQYDGKLKMAKISTSNHRNKLEKTSNIMVGDLEEDDDDIAFRNYYFEDASDDYSDEDISNDEEVTELNDVEGDEENSSEKKNNLAKSSNADTKRFSFSNLMNIFLTCIVFPMLAAFYFSLLWEEVLRALENRNRFRFGSRNVDEEALSKRQEIVKEMDFQVIEIKSEIDDLCAICLDSFSPGEQTCKQDATPVTTVNGITRGSAGTKLQNKQKEMVKYRPIIINSAIPNSNVCKDNSNMITTSSNAACSSYNSAPSCCDLNVVLEVNDMKKSVRPIEKEKEIKFKVGKEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZR3</accession>
    <name>A0AAD5TZR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SCY1-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SCYL2</name>
        <name evidence="3" type="ORF">HK099_004834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000354">
        <property type="protein sequence ID" value="KAJ3219051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14011">
        <property type="entry name" value="PK_SCY1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF6">
        <property type="entry name" value="SCY1-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="690"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="699"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="822" mass="92710" checksum="03FB76DFB54D51A4" modified="2024-05-29" version="1">MGNKLTKEYEIDKDQVGSGGPGNFWKITNAIKISTGKNCSLFIYEKNSLEMLNPLTKTAQLKKEQDRVNDILKKEAQTLMRLRHPSLLEVTEALSEDRFALAFATEPIICNLSNVLGNFTNFSCNREMFQEKYELDELEVQKGILQLIKALQFLHTNKIIHGNVSPQAIYINSKGDWKLSGFNFSTNTNTTTTPQDIYHYLTSYPPYCAPYLEFLAPEYALEGKCELSSDGNIKEQNIDFVKKKLVWSLGCLIYSLYHKGKSPLDCNQNFHDYKERLKMLDGINFHAGSIPPPLANLIKLMLTTYPSKRISIFEIQNNSFFDNILVSSIKFLETFVEKTQVEKAQFLKGLVRVLPQFSERLVQRKILPGLLNELKDKVLSPFIIPNLLWICEKMNSDVFIEKVLPSLKIVFKMTDPPQTIVLLLSRMDLFLKKVPSPELFRSDIMPLLYTGLEVPIPMVQEQALKAVNCVLDKLEFASIKSVLFTKIYTLYTSSQILAIKVNSLIAMHAMCKALDKFTLVDKLLPMLKLNRTREPGLLIAILAVYDEITKYLDKDCIAQDVLPELWKMALESQLNVTQFKKFMKVINELSKKVEELQIKHLETVSNIEGVSKMGDTITDFSKLVLTKQQIPDTENTNRSATLFTPPSGSSNTANNNFPQSSILNNTNVQNSNISSFGNIQSSADFSNNYQHLNSGYGGSNQINSNGNQQQLDFSNSKYAQQPVSSYPQKQHGSYHSSVGMHNQKTINYSTQSFNNINSSGNTTPSLFFKDAFPVSNTSQHSTFVTNFSSGNNGILKPTMAGSTSITNLSGSKENIKEFDPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U054</accession>
    <name>A0AAD5U054_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleolar protein 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 4">Pumilio domain-containing protein NOP9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NOP9</name>
        <name evidence="9" type="ORF">HK099_004536</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000322">
        <property type="protein sequence ID" value="KAJ3219890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U054"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="repeat" description="Pumilio" evidence="6">
        <location>
            <begin position="368"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="6">
        <location>
            <begin position="405"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="6">
        <location>
            <begin position="583"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="788"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="872"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="954"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="962"/>
            <end position="972"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3219890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1141" mass="130226" checksum="1A11285B84C4CF70" modified="2024-05-29" version="1">MSDEVQMERKKRGKRGGQKIKEKLLEQKKECKNLIQVVKDEIVLEKPKKKSRRGGKRNKSKSEENLVNTDESQNVLMEVTDEKNAGCSLKKNSRLDEKNLKKLKKTKLLNNDTRTYFLELESKLDNPEFESEEELQNLEINMAKDFDGSRIFEKLMIHANDFQLRILGENLFLFEDEAEDNVEPKCTLKSLFTDTYSSHVIQTFLQISSDVIHREVIGESIVEIDGSDLNLPKSMTEIVLELCNILKNDWSEIMKDQYGSHLLRVLINLLSGERMLEDSEIRSRNSRFFKLNNTSAIIKFNKSRERKVPEEFKKKLIEISSLLTKNLTHAEIKQLAIHPIASPVLQLLVLNNGLDQTFVKILLHAESSNTSFFNILMKDRVGSHLVEKIIDCANEEEFNEIFETNFKGNLKVLCLDAISNFIIQRLIANSNKHYLKIIIEEICDHFNDLFFNQRAGVVEKLVLSSGKLNISCEKVFDGLLKAFEIKSDDDFKILLGCIISLRNPTAFGNTNIIKSNMLHGSLISQHIFSFFPSEFVLKLEESFLSLPVEDILKYVKHHSLSRVVEALIKSRKTKLDTKWKLCDILLGNWCDLAKDKYASHIIEKLWQFIDVPRKTIIAKELIAKKTILENDKFGMIILRNLNVANFDFKTEEWKKKEGLVEKKRKLFQDIIGDFDNSSKNTVTAVKNDVVYAKLKAPCNQEDLNSIFKSFNPVRVSIPEHELMKVSGVVLGFAEFTDENAKSAIKELNNKKRFNGRLIEVKLDSKKESREKKLNKLGALKVNTTEKTTILTVKDYPETFNKESISNLFNKFSPTKIQMPKQSFNGKYKGYAFVHLGTKSAENAIKELNNKNIDGHLIKVGVEVSRKVGFQKNILFVKNLEKGIHSETLSKIFNKYRHKECRIPRSFKKSPVKYGFVEFVDKGIANRALSGLNGVKSALNGGQPLEISYAKTKSWRNGEPTKPKNSVETTKTTHAGKRPTRLGIGLTEKKKNVDKKEEESIKLNNIKWAAKNLLRDFDNLILVSSVQDIPDVIDTDMPYGVVVGNSPSELKEQVKNAKISAQQWCEALKNELCNNLKLSTEFDVSIGSPGEVVIDKINQYKPDFVLLGTHNRGAVSEFFMGSVSKYVLHHTKIPCVIISESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U059</accession>
    <name>A0AAD5U059_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000524">
        <property type="protein sequence ID" value="KAJ3215728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U059"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3180">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="226" mass="26055" checksum="DA1D1D2E8F12AEBE" modified="2024-05-29" version="1" fragment="single">MKSLVELCITVIQKNCPMNQLMKFVPVIPFYILPDLINFGTLKKDQLLHLENLVNDSTLLHTNLIWKNLYRNDFKKLVTTGLEIFKGKKKNEELLEDCGLADNEGKECNEEDDEGGDYWKTLYLRKEAERDENIRRARENCKLKYQNIQKKKIQKLDYTPKTCYKKSSYKPLTMFEKAKVDVSKSYIALSRTTSSVIPSNFKSSITSNDADSSSKKNKSATQSDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U072</accession>
    <name>A0AAD5U072_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_004765</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000347">
        <property type="protein sequence ID" value="KAJ3219232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U072"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF2">
        <property type="entry name" value="INACTIVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="553"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="158"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="14">
        <location>
            <begin position="366"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3219232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="751" mass="87191" checksum="E71665A5437024ED" modified="2024-05-29" version="1">MAEHQIFDAVVQATEKDKDFVEKTLKETPKKSEYVLTFGETILHLACLSRKIDKKTFRANDNENANKRFHLEIALIIAKLNPKLISTQIKQNFRRAGQTCLHILALKGDLELFEKLWELVPDKGTNGTSILNTLKAKGTEFDIDDKRKDHSTPGLSYLGETILSFAVCSGNGKLVEFLLRNDANPSIRDDYGNNSIHICCYHGKFGQIFNKKEKQNEFLVQHNLENSPYSVIRKFLKEKEDEGFADQKDYLEKYVTEKFADNEKKEIVNPFEALNKMYLTPFNLAISRGHCEIFDLLKIELWSYPNISCSVYPVHELDTFQPHSTGKNPYFRSGLQIAIENNDVNMVNHKYIDLILRVKWETYIKKIFLMEFLFFTLIVLSLMTVVATLPHEFEERLNYRKNSYVRLCAELITFVGAILLLGWEMWKLRNLGLQFFSRFVIQSIELESIVLGFAAIIGCFLLLNYAKSNQNIGPLVLIFYKMVSKDLVMFIFVMACLFFGFAQAFYLQMQIASVKSGGAVLGWDTLYGSVMWLFRYILADYEYLDFAYARTKVFATGLFICYAILTTVLMLNLLIAMLNMSFGNIFKDQQRQWRLQWANMILSYDLRIGSKAYPLNMKNPFNWFYKEKLGFKFPSYIKGGRGKTSVFDSDRYVFAVYDRRRINRTLNEAAREEVKINHIMFTSPAPGVRPNHLRILPKSMWHFKEKVLYDLDDKVIKSFKSAEFLEKSPSAYYSEPNVKQSAIDMDITEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U099</accession>
    <name>A0AAD5U099_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000330">
        <property type="protein sequence ID" value="KAJ3219722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U099"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="168" mass="17547" checksum="9376C65B9D929E58" modified="2024-05-29" version="1">MCGGIANFKCADGLVCDIAPVRHLSDAAGKCIKESSPQTRENLISKVGEICHERSVTGTHICGSGLICKENPNVSDVGGVCVVDEQFPPSSSLRLSSTTTQTSTTTQASTTTDSITSASTNSPTPSLPVPQNSTPTTAANSNSNSSFNLSPFKSISFFFSLIIALYFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0A7</accession>
    <name>A0AAD5U0A7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000347">
        <property type="protein sequence ID" value="KAJ3219234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="285" mass="31298" checksum="37B0C202DD082482" modified="2024-05-29" version="1">MSGMYLGSTISLISKSDIRYVGVLHSINQAESTVSLGQVKSHGTEGRRSGLDEIPANDKIFEYIVFRGSDIKDLHVVTAPVQAQSQVPNDPAILTTQPPPSEQGQPSYFNNSNLPLPHNTMSQPYLPPGMNNYMLQQAQQQQAMFFQQQQQNFWQQQQQQQHSNNAVPAFSAQQTLPTQNASQQQAPNSTSPTSTPIKTENLEEGSTEKLNNDLMKLNLNSSSKKSTTGSTFVTENNLVVKKEKKNVESTTNPRSASPAYKNVTAEDSFGQSGIDNEKPPAGEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0F0</accession>
    <name>A0AAD5U0F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LIM and senescent cell antigen-like-containing domain protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LIMS2_1</name>
        <name evidence="6" type="ORF">HK099_004336</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000300">
        <property type="protein sequence ID" value="KAJ3220459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0F0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045216">
        <property type="term" value="P:cell-cell junction organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001046">
        <property type="term" value="P:positive regulation of integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900026">
        <property type="term" value="P:positive regulation of substrate adhesion-dependent cell spreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000009">
        <property type="entry name" value="Paxillin isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017351">
        <property type="entry name" value="PINCH-1-4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24210">
        <property type="entry name" value="LIM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24210:SF0">
        <property type="entry name" value="LIM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="5">
        <location>
            <begin position="21"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="5">
        <location>
            <begin position="84"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="5">
        <location>
            <begin position="275"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="364" mass="41800" checksum="471E0D26DDD71819" modified="2024-05-29" version="1">MFQNLELKTVQQSKPVEICIGQCFICKEDITEKMSYVTVENNIFHQYCFVCNQCLEPFTNNDGEFFQADGGYYCEFDFLLLHGSRCVRCGDIIKGRFINALDGKWHEDHFTCELCSRPLSGGSFFKKNGKPYCKVCIEKLKMNDFLCKGPITDNKIIYQGQKLHAYHFTCTTCKITLSSQNCKEFESRLYCIKDYDRMLSLNMICFGCRKTLTNSRSVTALGKQYFIIRDSVQFNALIVLVSIPNILYVASVKNLLHQKLFLNTKIKHIDEIKGDLCGHCYEPCVGGDSERGVVIALNRKWCEGHFCCVACQITIVPGKTKFSELDSKPYCLTCWNSLPFELRTNLNNFAMIEKKALEEKEKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0G9</accession>
    <name>A0AAD5U0G9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cilia- and flagella-associated protein 57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">WDR65_3</name>
        <name evidence="3" type="ORF">HK099_008137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000863">
        <property type="protein sequence ID" value="KAJ3210969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0G9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052993">
        <property type="entry name" value="CFA-57"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32215:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="336"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="664"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="776"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3210969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1080" mass="125166" checksum="3D00F7E9ECB18926" modified="2024-05-29" version="1">MLTKRRYLYMWNHEKGKLIASSKASNNNNSEVRQISCNPFDQNVVQTCVIGTALFRLFKFLDGQFRIVTQQKPDHDLLCHSWITESRIAVGTNTGKILIYEHGEMLIEILYVPSEIEPVFPSFNSLVHLSGGFLVGTSNGSIVLYEKTDDEQMYKKSRDFELENGSVATISINPNQDSAVCTLKNCQIYHISLDYDPNKVEDLKVGRDQSLFQEFHWDQIVGLDTCARKPILATCGTDKSVRIWNYAENVVEVSKFFKDDPCSVAIHPSGLYLLVGFNDSLNLLNILIDDIRPYWTTNVRGCRECRFSNGGQYFAAVFGSTIVVHSTWTFQQVFNLKGHTGKVKSIYWSSDDRRLLSCGLDGKICNWNMRTGKKEWEHEDSKFLYSSISCTPDSKLIYVVGSDGVIRELNNDGALLRDLPIKTCINNVLIARSGRYFFASGNQGVIRALKYPFVPESTASNAVVPTGAVINALEQSLEIQCHSSNITRLRLSYDESHMFSVSEDGCLWIYKVLEKQAEKKAEKDLKFSDEILVTRSDLKQTFKVMSELKKTVEKIVATFDRKMEAESVKYTELDEKNQTLQKQWESQMGDMEIFHKKRIQEINAFYDKKILEKGNEINKIKMQLAKQGEEYRINLLDIDEDVNQEIISLQYSYEQKMREERESLSAIREENLAMKARFESLNKQIEDRKQEIVKMIQEEKRLHGIIKSLNKDIQVVKREMQERDDTIMDKEKRIYDLKKKNQELEKFKFVLDYKIVELKKQVEPRELDIIKLSELIKAMDEELNGYHHKYDEKESEIHTLSLKLKAAKLEVESEKLNKAQMKQICNKIESDVEQVYKLIETPNEMKKQLIAVYIKYENLSEQPSTLKSKPKLRINGNFNKSDNTVCKVTMSKKNPVLDESNYDTSREREHKERTIETLLHSLEGIKESRYNDNLRTMQENVLLLSEVNILKKALKSSEIRTSRLEKGIKKIEQGKFNFNLLLTESNNAVEFDKNDAFNKNFYQKKKTSNDFNFDLPNFFNILEIQEDIQKQHNGEFVDEYSKNDYIFESSESQLNSNCESYILCKEVVLNKPNLKLPSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0J5</accession>
    <name>A0AAD5U0J5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000644">
        <property type="protein sequence ID" value="KAJ3214165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0J5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="229" mass="27171" checksum="C9770F2132D9009A" modified="2024-05-29" version="1">MISRKLLGSNLIKSNVHLKNTKITSILFLSKRFYASNHKDDHPKPKTKHPEEYLEVARNWPHEYYHPEHYNITNKPSYTHPSEFTEENPLGTETVEDRVEDFSSPIWTKVLIFGVLGLTLYRTNEFYSQGKDVHPFTLFLGNLRAFKNDDYEENRKWVQLHQKEANDRMIDRDWEPAVIHRVRFSDIFQRASDHLIEPGTQIDVSDIKFKHSWQDDDEIFGVPYPNKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Q2</accession>
    <name>A0AAD5U0Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL-31</name>
        <name evidence="4" type="ORF">HK099_005755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000463">
        <property type="protein sequence ID" value="KAJ3216724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Q2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.440.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="122" mass="13925" checksum="02A3870498D41BE8" modified="2024-05-29" version="1">MGKEGKKTSKKASALSEVITKEYTIHLHPKVFGQTFKKRAPTAVKVVRKFAQTQMKTTDVRLEPELNQALWAKGVKTVPHRIRVRLSRRRNDAEDAKEKLYTLVSYVPTKNFKGLTTVTVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Q7</accession>
    <name>A0AAD5U0Q7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein transport protein sec16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004458</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SEC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000315">
        <property type="protein sequence ID" value="KAJ3220124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09233">
        <property type="entry name" value="ACE1-Sec16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024340">
        <property type="entry name" value="Sec16_CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12932">
        <property type="entry name" value="Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec16 central conserved" evidence="9">
        <location>
            <begin position="1152"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="8">
        <location>
            <begin position="1316"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="465"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="557"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="981"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1688"/>
            <end position="1712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1875"/>
            <end position="1934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2015"/>
            <end position="2214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2243"/>
            <end position="2280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2295"/>
            <end position="2411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2423"/>
            <end position="2633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="557"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1000"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1086"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1108"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1696"/>
            <end position="1708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1875"/>
            <end position="1888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1897"/>
            <end position="1934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2046"/>
            <end position="2111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2128"/>
            <end position="2142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2168"/>
            <end position="2214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2243"/>
            <end position="2252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2257"/>
            <end position="2279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2309"/>
            <end position="2320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2327"/>
            <end position="2336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2349"/>
            <end position="2365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2434"/>
            <end position="2447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2453"/>
            <end position="2466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2489"/>
            <end position="2500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2501"/>
            <end position="2515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2524"/>
            <end position="2533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2534"/>
            <end position="2548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2549"/>
            <end position="2569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2598"/>
            <end position="2624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2633" mass="288734" checksum="346A0F48E3E1A83D" modified="2024-05-29" version="1">MNNRNKPPIEHKTVPFFGNGQVERKKTPVADRPANSLFGNQTNDNFFSRNRTDHSVSPVNNLFGNNANSNQQQKLNQATNHFFDSISQNNVSNSQTSSETNLTKSNNSKYMEANDAFFAALGGTSANKSQSNLSAKNNAKNFFSNATPESASKKNESMDVKKAQQNTNFNDFGEQSNTMLQHQNVDEGNVNSSHNRQYDQHNAPALNNQYGSRVAYPNQQSGSSKFFDNTNVTQQQLGTDTFTYDSNISHESGTKTSIFNNTIVSPVGNSEADFQQPAGFANVINNDTNGWDTLSLPTSEYDHFAEPGMKGNHKSNAHVTHKQMDDIDNGLHRSQPEVVTEVLQEEVTYTSSLDYGSNSFLQNSTEILSQKTVITNAASPDILNNAQNYLTEVKPEEKNSKNFNQEFVDIDPNQKVFENINAKDDMSEKMHPKAMNQDADDLDILVKMSQDSNLKNTSLLNDHFSKQTHNETNRNNSIFENTVDKEFSNSTEPKLNNSFPSPTKDTVLTSNKSNFSENLDIKTSPSEMYLNGKEINSLENKLIFPSVYQNAAVTSSLKGGLSTPSANTVSSASSTFPPNTTTNANNPATSKKYHSKHPENKPPSDAAKFFNNQSSKPNAFDSFNRPIPDVFNIGNGFAQFSQGGPHNDAGKSNTDGKKDLYSNANTFSNPLANNLNTGNDNNQFANNSISNTQNFASQQNAFQQSNNQSATSNYMQNSFNSNNPVSFENAPVGNQVTENFQDPNRNVYNQNIETKEQVVNNYDHSFDNASIHNSGYQSENTNGYVNDTFQFNADNANQIQYNSAFGASVTENKGNFPPSTIYPQCQGYGQANYTANVLKSQTDIIDQQRVQDVNEMMHSADSNQGYNSVNYGTPQHTGDKAFSISNSVQQTYSTQPFSNQIQDHTLSYQPMGNDTTETTPGSVVNQHTYSDATYSNQETNFGVSHSADSATMSTTHVYGEAIANNYSATLNSTVVQEDKNLNSASSAPPYDLNYHHPQPTAYNIKSSNSYQTLSSISRPSSTGPVNKSRKSSLPLGNPPPALLEVSRPPSVSGLSNSNSNVDLHLQSHTPPLPYHQASLKRLPPSLGQSGSNTPSPYTSRKQKELQMRANNRSYSADAAQQGSVLPQPFSPPTEAPVAHEGFYDPLLRHRGHAVATWGLGKLVVTGPKRQNRFMMGANGQQSLVEKAYNGPITIYTVKDVLQPEFLEAVSSFPGPLAGGKTKTKKKDVIKIIEDKIQNLEIILKDLNLRPQENDQLKKNLIENESILLKWKLLKFFCENDGILFTGKSDPAIFQVISESVLSDRSKIATGSAAEEIEKFLIKADRVGACKFATQAELWSHAFILGGNDVNTFREVMLKFTSSSEMNSNQTAHSSKGGLCGDLTSLKVFYNVIGGSGPASLNDFLPINGNFTCSADIIRKWKEILIMVLSNRLPGDLSFCSVLGDRLHDYGYFYSSQICYLLASATPLLGAEVPNSKMILLGSNPNTDLANCINAIQETEIFEFSQTLAGGLASGLPHFQAYKLSYAHLLADIGCMELAQQYCESIDTFVKSYSKGSPYFHRRFLESLRVLIERVGMYQLTKGQIAEAKEKGGSWWISALDDMTTKLMNGVVGLEGEAQIKKAPTPQPATVSSSGVLNYFSSTKLEEVENRPLSTPLVLDPSVSFTAPSVAKTASMNSMYSYGYNPGSSQTIHQSRNKNNISSNSSYPSVQDTQTYGISNETQKSNLSNVLSQDYTNYDNSANVYSENMPQGQKYANFDNSANAYGDNMMQVQEYTNFDNSTDVYAENVFQGQHSQWTHHGAPQNGLYQTNTFENINGSTRVHPDTSYANQSSFSDNQHPFIASTNVENSVIANEYSHGYQNDLTTYTNNLSNYQQQSNTHVSTSQSIAHTKPPSPSPSITNQSRTDYQSNTSMQNDKSQNYHPASFVPSYQSQPPTAHAAFTYQKPPTPTPQTSYINQIPPNGQAVYTNQKPPTPTPNAAYSNQTQQLTNTLDQDFGQGSKSHNTFKHYDTTPASSTFTDPLPQNRGGPIIQNKNFRTGASPVPSSPMQTSANPSLQENFYATFPENNYNTPPGNPLQHNSFSQVKSGQESNSINRASSVPPSPSYNQQKNIGGYKGSSKSSVPPSPHQTSAYPSILNNISTSVPPSPSQSYMPPSVNYTGPNKGYQPATSIPPQQSNFNNGYQNSFSLNNSAPTDSLNVSTFDSTPQDDSLPAVSNQQLENQEEDDFLGLGNKSIGKLKAKTVNSGNSVTPSYPAPEEKSKEKANESDEKDKTSKDGAESGVIKSFWSLFKTVKKNDEPSATQIKQGKPLEARFDEVKKKWIFPGNEDKDEKKDLGAPPIGPIPPSNTPINSSPNSRSASPNPADIAAGTGQQTSYPPVLGKRTGGRKNARSRYVDILNPDATGESSAPAVASFLPTPAFSAGVTEPKIMTPTSSSYNNLTSYTSLGSEHNISNHELSRETEIDNQHLLNPPHSNQSIEQHTSDGRKPSPASRRASPSPQLRNQPSPTMQNGFNDSRPPLPNNPQIFHSQDSNSHHDEKLPFRKSHENLYSNSLASQPTRNLKASPSLPTMPKNLAPRPQAILYNPNGGSVMNKKISPPNSSSNLLRRPIQQNQPQKLSNQQPRAVVVPTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0S9</accession>
    <name>A0AAD5U0S9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000385">
        <property type="protein sequence ID" value="KAJ3218346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0S9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000104">
        <property type="entry name" value="ATP-binding cassette sub-family F member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF117">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="179"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="506"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="287"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="725" mass="81363" checksum="336F9A640912C095" modified="2024-05-29" version="1">MSKSKDIRKLFKEYKLEEDLLSYIMSYFEDESNDFTDEGLREFLCPMLSESVDDDGVKNLVKKICNLTTNNNDNSNAFETRKLEGGVLNMKVGEDIASLLKIDPAVKSVDIRFTAGRTGKSIVDQKKLRQAEERLVKKREQRGDWLDADGIPIWNPDIKPDIIVNQAKVRDLDSKSKDIKIENFDLNFAGKKILQNATLALNYGRRYGIVGKNGIGKSTLLRAIAHKDLYVSPHIKILHVEQEAGGGMETSAIQSVLDADLELQALLKEEEKLNKLLSSEKSSAIEAGKASNRLKEIYQKLEELEADKAESRASAILNGLGFSPEQQKAGTGTFSGGWRMRLALARALFCNPDLLLADEVTNYLDFPAVVWLENYFQNWKGTILIVSHDRSFLDAVATDIIHFKTEGLEAYKCNFTTFVATRAEKRKNQLREYESQLQYRQHLQAFIDRWRYNANRAAQAQSKIKILEKLPPLVPPSKDDMDGLGEGEVSVYFKFQEPEKISPPILQMSDVVFGYTKERIILNKISFDIQMDSKVAIVGPNGAGKSTLIHLLVGDISPNSGICHRHGRLRIALFSQHHVDQLDLSKSSVGFLQGRFPGKVEEEYRRFLGRYGLTGTTALQPIGTLSGGQKSRVVFAWMAMLNPHILVLDEPTNHLDMDSIDALSVALKEFKGGILIVSHDQRFLDTVCNEVWVCQGGKLDKFEGKHGNTDGVVSQYKKSLLEGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0V6</accession>
    <name>A0AAD5U0V6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Phosphoacetylglucosamine mutase</fullName>
            <shortName evidence="14">PAGM</shortName>
            <ecNumber evidence="4 14">5.4.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">Acetylglucosamine phosphomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 14">N-acetylglucosamine-phosphate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">PCM1</name>
        <name evidence="22" type="ORF">HK099_007765</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23804"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="5.4.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14 17">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="4 14"/>
    <dbReference type="EMBL" id="JADGJW010000787">
        <property type="protein sequence ID" value="KAJ3212278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0V6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004610">
        <property type="term" value="F:phosphoacetylglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03086">
        <property type="entry name" value="PGM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000003">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000013">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000023">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049023">
        <property type="entry name" value="AMG1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016657">
        <property type="entry name" value="PAGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21405">
        <property type="entry name" value="AMG1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016408">
        <property type="entry name" value="PAGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 14 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 14 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="19">
        <location>
            <begin position="110"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="21">
        <location>
            <begin position="219"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="20">
        <location>
            <begin position="314"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="18">
        <location>
            <begin position="473"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="15">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="17">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="392"/>
            <end position="394"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="517"/>
            <end position="521"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="526"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR016408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR016408-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF21405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3212278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="561" mass="61759" checksum="64C6132EE1D0D511" modified="2024-05-29" version="1">MDVSLILKLNEEHKKLEQAKFTYGTAGFRTLASTLDPVLFRVGLLASLRSKKLNSKFIGAMITASHNAAPVKIKSDFPKLTFKDNGVKLVEPLGEMLVQTWEPYATKLANAETREDIVACLTEIIETEKIDLTKQSNVAVARDTRPSGEKLVESLKDGVISLHGNLTNFGVLTTPQLHYNIRCLNTKAAKHPYGEVGEEHYYKKLSDAYKSITRGFKKLSPLYVDAANGVGAKALLALAKEIGSEYFDVFIVNADVANSEKLNFECGADFVKLKQKAPTGLELKSGMRCASLDGDADRIVYYYADHDGKFKLLDGDKIATLAAGFIMDLVRKANVTINGQPPKFGLVQTAYANGSSTEYASKKMQVPVVFTMTGVKHLHHAAEEFDIGVYFEANGHGTVLFSENVINAFSDVNGKTEEEIKSLNILKALSIVINQAVGDALSDMLMVELILTLNKQSLSDWDEAYTDLPSRQIKVKVSDRHIFKPIKADTELLEPLGLQEKINAEVKKYSSARSFVRPSGTEDVVRVYCEAKTQKDVDELSVAICTLVFDGYGGIGERTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1B2</accession>
    <name>A0AAD5U1B2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Bud emergence protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BEM1</name>
        <name evidence="7" type="ORF">HK099_007418</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000717">
        <property type="protein sequence ID" value="KAJ3213379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1B2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051228">
        <property type="entry name" value="NADPH_Oxidase/PX-Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706:SF2">
        <property type="entry name" value="SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706">
        <property type="entry name" value="SH3 MULTIPLE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="39"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="159"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3213379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="386" mass="44566" checksum="673CF3578D903F26" modified="2024-05-29" version="1">MNYSSFESHYESKKKPDTLSPLQLPARNSSHPTHVFNMAPKRVVRALEDYTAQYAGELSFRKGDFFFVINDDQNSHFEVINPAEKSRGIVPSYLFNQLSNTVEPAHSEQNNDYYDERQAKQTYSNGSYHDDKYYNQNSRSAETSPRSPTTPIIYNKRNTPQTIIKTNVQSVDLKPDGQYWFTVEVTRSDNMRHLLTRKYDDFWILQISLLNFFPIESGRKGRPRTIPFLPPPEKNLSATLAQKRRAQLDVYIQELMSLRKNIKESAPMKRFLMPKQHDVETSLEVEFDQSVTLMDLISGYGESSDVKITLALTNGELINWECPDTVSYNELMYACEDHLGVAIPGLGYMDETSTLLELHGDDDLQLLVKTNTDKLVFYIYDPNYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1F8</accession>
    <name>A0AAD5U1F8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 5B</fullName>
            <ecNumber evidence="3">3.6.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Translation initiation factor IF-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_003602</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000238">
        <property type="protein sequence ID" value="KAJ3221298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1F8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03703">
        <property type="entry name" value="aeIF5B_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000013">
        <property type="entry name" value="eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000026">
        <property type="entry name" value="Eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10050:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000112">
        <property type="entry name" value="Eukaryotic translation initiation factor 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029459">
        <property type="entry name" value="EFTU-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003078">
        <property type="entry name" value="PRK04004.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14578">
        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="16">
        <location>
            <begin position="518"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="295"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="211"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="456"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3221298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1111" mass="124618" checksum="3A316D915BF70E0B" modified="2024-05-29" version="1">MPPKNKKKNRKDEDLDAEYEFNETLSEPKDIQLNQDEDGNDLGGLMGALARKKNQKNKKNKKKNDDDEEDAVAMLEKMDQIEIKDSPSPVSSPKPQKKHKEEQKEEAAVEEEPVVRIKTKKEKEKERKERQKLEQKKLKEKEKKTETIEKPEEKVEEVENENDDENNDEDGKADKKKKKKKKAVAKEKEEPAKPKRKGPPLGALREMLLAKEAAEEAARLKAEEEKRLIEEEERKIKEEEDRIAELKLRKKEKEKAKKEELKKAGKYMTASQKAAQKMAQDRLAATLAAGAISVAALQKTESEKPKKIVYGKKKTGKKVAPQSSTADNSAAASPVASSPVASPKATKKEVQVKEEVKEDWEAEEERSDVKDAWDASSEEEMVNNDSVDNVQDEWDASSEEEKVVEVKANFVKKEEAKPVQTKKQQPAVSKQPAEIPKKTAEKVASVKPIKKSEPVVESEEDDEDDEEESDSEESSEEYSDDEELTSTQKMALKRKEEAAERRQQRHKEALAARSADDLRSPICVILGHVDTGKTKLLDKIRQTNVQGGEAGGITQQIGATFFPMSAINEKTKKLRENLTKQVEYKLPGLLIIDTPGHESFSNLRSRGSSLCNIAVLVVDIMHGLEPQTIESLQLLKDRKTPFVVALNKIDRLFDWQVYPNYPVQESLKLQKKHVIKEFNDRVEKTMLAFSEQGLNSCLYYNNKNFSKYVSLIPTSAHTGEGVPDILHLLVELSQSRMTDSLMYLSEIECTVLEVKVIEGLGTTLDIILSNGILKEGDKIVVCGTNGPISTVVRALLTPQPMRELRVKGEYVKHKEVKAALGVKLVASDLENAIAGSRLMVIGPDDDEEEIMDAVMEDLTGLMENVEKKGVCVQASTLGSLEALLTFLKQMEIPVSGINIGPVHKKDIIRASIMLEKAKEYAQLLAFDVTIDKDAQELADQVGVKIFKADIIYHLFDSYKSYMAELAEQKKIDQAPKAVFPCILKIIQVFNKRSPIVVGVDVIEGVLKIGTPICVVGEDGKTITDLGKVTGIELNHKQKQIVKKGEPSVAVKLEVAHYETPKTHGRHFDDKNLLYSHITRESIDILKSTFKQDLNKEEWGVVVKLKKILNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1U0</accession>
    <name>A0AAD5U1U0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000482">
        <property type="protein sequence ID" value="KAJ3216369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1U0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="508" mass="58088" checksum="494B7BEE0B9D9656" modified="2024-05-29" version="1">MTSKYSSFSRKASMLFNSFFPDKKNNKKPSNEDDEVNTLENHLTNLSTSTSNSKISSQNIQHHTKNPTRPHSTSSLNLNEYHSKEKKYDTQHSKRHSLKNRKSFNFFKFNFSNSDKHNKRDALDAKSVISVKSIKTFKSFFSKESDDDDANSVCPIEDNVHNTIDTDNETVPNHIKVTPRISLRKLLTYKKDLNDDDDSLTDETASSLKIDNLDEISVFKNHISVFTTLTRGPQNFGLNIPEASPLKNRLRIVEEVSDSDEISLVNCDVNKVAILEDSEDYDHIEDIYSSYADIPCQSTQKLDEYHLTAEKNVDDLSNDSGETTKNEISLQSTKISELSSNNYKDGHQVLDNIPIDVTSVKKEKKKSAEKNSVKILSAEKISSQNPNFQHKGNELTSMISTVDEKYLVDSDSINNEPTLSNEPTLENNEEDASSSDVIQDEKKYNEVLDKTKIPFYFISKKSAYKKKNNDVKKVKLKPDTSFQSMRDSRKSFIFSEEEVKDLRRYVHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U240</accession>
    <name>A0AAD5U240_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000292">
        <property type="protein sequence ID" value="KAJ3220549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U240"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042229647" evidence="2">
        <location>
            <begin position="22"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="538"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="695" mass="74841" checksum="E3A6FEABE92DD0FC" modified="2024-05-29" version="1">MKLNLLIVLLYSTGIVATATSFNFPIATPTATKTTFTFPTATRTTFIFPTATRTTSVFPTATRTTFIFPTATRTTSVFPTATRTTFIFPTATPTTIGTTLIFPTATRTTSVFPTATRTTSVFPTATRTTSVFPTATRTTLLFPTATRTTTIFPTATRTTSVFPTATRTTSVFPTATGTTFIFPTATPTAIGTTFIFPTATAETTSTPVYTVTAIATTVFATFTAIPTFATPVSSVTSTATQLPLPNSPKNVSIRNFNSAGSSCPAGSAIASIDSNGYFLSISLGIIDVSKGHFEQITEKKSCQVNLNLDFESGWQYRLTFANSRGHYQLENLVTATQKFANYFTGDFFEQQTAQITFNSGVSKYSFVEMFSNEVWSPCSNDAALYIISQVRIDGPGIGYIAIEPVEGDATYKFSIDWRRFAAVILTSFTTAALQFQDFEISFAPLGTAEAAAKKACPAGASDNQEKADIANVAEIDIFNAQLKDPKITEEEKVVIQQNKIKNKVLKLTCGLEAAKLKGNEEVVQEKLQKLAKNISLDKAASSSAKTTKPVSSPTPKPSKPSTQSNTNVGSNKIQFSDIDISNAAVGTAEVNAKRVCPAGSPDNQEKADIANKAEVEIFNKKLSLPTLSAKEKSLIQQDKIKNKVLKLTCGLEAAKLKGNEEVVKEKLQKLAKNISLDKAAAKKTSKIVEANKNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U273</accession>
    <name>A0AAD5U273_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000328">
        <property type="protein sequence ID" value="KAJ3219740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U273"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="441" mass="49962" checksum="560A888A904CCFC2" modified="2024-05-29" version="1">MEIDVVYFSKTVKEVAQELQKKITFLKINNNNVLPLVLYETVTIDSSSAYEFDTLITVNFAENRYKLRTYVINELGHVLVTIVKSYGQLSGRSIKLRLWNTSETEDVTIVNMSSQAVQIGMPGYGKRIVSKVGDGTYINIDSNKVVTIKEPAMLGEYPSKNEPNFDLILSGEVTPGVRTETDKKWTVTRDIAISYDDGSVTTALSIAGCIVAYRANASMDLYPHQNSSRDGKPLQYRGIYGVTTVSVGIPEKRYTQIMEKLHSKYKQFKYVADEDIENGCVWINASIGTKKYPEDNDAYDEMFQNQVIVAGRDKNTKYESLGPIRDVLRTFAKSLKVVIYGTLRVKAQLTHETEKKVRKYKLGMSVNYFQLYDISDIDGPGLRDVTEHSVTNSKFRPTARLTEILRSHDEQQDQDVEVLEEKDEDNSKIEDTAVYEDDDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U276</accession>
    <name>A0AAD5U276_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">T-complex protein 1 subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CCT4</name>
        <name evidence="13" type="ORF">HK099_003259</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000216">
        <property type="protein sequence ID" value="KAJ3221668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U276"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03338">
        <property type="entry name" value="TCP1_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000010">
        <property type="entry name" value="T-complex protein 1 subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012717">
        <property type="entry name" value="Chap_CCT_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02342">
        <property type="entry name" value="chap_CCT_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3221668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="529" mass="57166" checksum="CE57299BAA8F45C6" modified="2024-05-29" version="1">MSTQKSTAPTQQFKDKGKPVEVRISNIIAAKALSDAVRTSLGPKGMDKMIQGGTGDVLISNDGATILKNMMVMHPAARMLVDLSAAQDIEAGDGTTSVVVLAGSFLSATEKLLEKGIHPTAIAEAFSNASTKAVEYLTEMSNKLELSDRESLLKAATTSLNSKIVSQYSNLLSPIAVDSVLKVIDPATATNVELKDIRLIQKLGGTIDDTVLVDGLVLNQTVIKSAGGPTKIEKAKIALIQFQLSPPKPDMDNQIIVNDYRQMDKILKEERQYLLNICKKIKKTGCNVVLIQKSILRDAVNELSLHFLSKLKILVIKDIERDEIEFICKSTGAKPIADIESFTEDKLGYADLVEETESAGANVVKVIGAKTPAKTCSIIIHGANHLVLEEAERSLHDALCVIRCLVKKKALIAGGGAPEIEVSQRLMAYAKTLKGMEAYCFQAYAEALEVIPSTLAENAGLNPIRIVTELRNRHANGEKTAGINVRKGTISNILEENVIQPLLVSTSALELATDTVKMIMKIDDIVSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2H8</accession>
    <name>A0AAD5U2H8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000189">
        <property type="protein sequence ID" value="KAJ3222152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2H8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="152" mass="17388" checksum="C84C8DB7134C5CEE" modified="2024-05-29" version="1">MSKNEVINEPEFRTFADIEALPHFKDGNDKDTPPIVFSVKRPIGGSYEFINENKDDIMYSISHSFSLLSWTASVYKKKNSKEKSVQIFTLKHKTSKKDGSITSIDSKDPTLSAKLIRRGNVRPTRCFYVQDMAGNSIAFEWVKTGNFYLTYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2N5</accession>
    <name>A0AAD5U2N5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Protein disulfide-isomerase</fullName>
            <ecNumber evidence="5 14">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PDI1</name>
        <name evidence="17" type="ORF">HK099_002691</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="5 14"/>
    <dbReference type="EMBL" id="JADGJW010000191">
        <property type="protein sequence ID" value="KAJ3222112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2N5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02995">
        <property type="entry name" value="PDI_a_PDI_a'_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000027">
        <property type="entry name" value="protein disulfide-isomerase A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000017">
        <property type="entry name" value="Protein disulfide-isomerase A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005792">
        <property type="entry name" value="Prot_disulphide_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01130">
        <property type="entry name" value="ER_PDI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF132">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11 12" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041784041" description="Protein disulfide-isomerase" evidence="14">
        <location>
            <begin position="17"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="16">
        <location>
            <begin position="9"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="16">
        <location>
            <begin position="324"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="47"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="374"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605792-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3222112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="479" mass="53371" checksum="AD008E321DDD2947" modified="2024-05-29" version="1">MKNFLILSTLVLSAFSSSEVHVLTNDNYGEFVKNEKLTLIEFYAPWCGHCKALAPEYEDAAEKLKEKNVKLAKVDCTVETEVCSSLQIQGYPTLKIFRDGTPSDYKGLRTSSSIVSTMVRQSQPALIELKAEAVEKFSQEDKVVVVGYFKSTDSEEFKTFQSTANKYRDDYQFGYTTEGVSTPKVTLFKQFDDKKVDFSGKLTSSTELVTFIKDQSVPQMDEIGPENYSAYVSRGLPIVYLFYGSADDREKYGGILKPFAKTFKGKLQFAYIDAVKYGGHGKTLNLVDTWPAIAIQDTTKNAKYPFDQSKPITKEALSTFLNDFVSGKIEPSLKSEPVPESNDGPVKVVVGTEFESIVLDKSADVLLELYAPWCGHCKKLAPIWEELGEHLKGSKVVIAKMDGTENDLPAGTSFQVEGFPTIKLFKANDNTIVDYEGDRTLDSFVSFLKKNAVHADSFEDVKAGSQDTDSHDNEDHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2P8</accession>
    <name>A0AAD5U2P8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000193">
        <property type="protein sequence ID" value="KAJ3222080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2P8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF18">
        <property type="entry name" value="HAPPYHOUR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="11"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="220" mass="24798" checksum="557247818F87C6DD" modified="2024-05-29" version="1">MDLKTDPSDVYELLEILGSGSYGDVYKARNKLDSTLSAIKLIKLESEENLDKVLHEVNFLRDCIHENLVSYTACYLKAGDIKGERTAWIVMNYCGGGSVEACYRSMKSPLNETEISCITRKCLIGLEFLHSKLKLHRDIKCGNILLTEEGEVKIADFGVSTQLTKTFSKRNTFIGTPFWMAPEVITSTQENETYYDYKADIWSLGISALEMAECGKEFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U352</accession>
    <name>A0AAD5U352_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000317">
        <property type="protein sequence ID" value="KAJ3220045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U352"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="118"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="166" mass="19585" checksum="18A4256D66CC0046" modified="2024-05-29" version="1">MNAKTTKTAIKETAKLRPKKEVQAKGVNYIHGLHMPKTMPNNWVLKQIAFPSPEANFKPFHTIDEGVFTEPRISWRNQERIRRGCMLAGIDPKEVGLKDKRRPDEKYVNKMLKFSGDVKKETENLVAKIDRREKIEENMIKMEERIQKWREEEKKLKLKAKNLIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3D1</accession>
    <name>A0AAD5U3D1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000146">
        <property type="protein sequence ID" value="KAJ3223058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3D1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF30">
        <property type="entry name" value="PHOSPHORYLASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="103"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="434" mass="50374" checksum="E7F3E6262A67DF7A" modified="2024-05-29" version="1">MIESSLDSTSHFNNFDQKLKPSNLNLNITIPSFSTDFLESLPESPVVPSQPTYEKLDSAFVSELSSDNYYLELTDDHTQGMERYARESVRLAIESTKKLTVDYKITSFLGWGEHGAVLGATRLLTRKPCVIKLIYKKNEVNLKPCTKTPEEILLFKTFNHPNILQFIEHFEDEDNYFLVTSRIVNYSDVDLIDEDKIQPWDECISIETPFANENIIRVPLRNGQCDLFSYLEKKQTLPIDKIKKIVFGLVKSVHYLHTELNITHGDIKEENVLINQKTFQSYLTDFGKANVRVKDKDGTLEYVPPEFIPNFRIKNKMANNKLKESSKNNNSTKDVEKNSLRYESGFEADIWALGILLYSCSTGLLSAREHLNFFELCSKEKYQKKYYPIEKNLNFNKIKKERDLVDLIKGMLTIDVKERYTIEECLNHKFFNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3F1</accession>
    <name>A0AAD5U3F1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000155">
        <property type="protein sequence ID" value="KAJ3222869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3F1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="9"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="55" mass="6532" checksum="1156DE3277B247A4" modified="2024-05-29" version="1" fragment="single">MKKKNTECIFCLKDDFSLNKVKQDQILLRDDEFSVFFDINPASEYHLLVIPNVHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3J6</accession>
    <name>A0AAD5U3J6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000136">
        <property type="protein sequence ID" value="KAJ3223279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3J6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038:SF1">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="2"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="160"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="223"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="237"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="284"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="300" mass="33903" checksum="0F0F5DA6AD9AD3C9" modified="2024-05-29" version="1">MSKLYVGRLPQTLSQLDIEDLFSKYGRLNHVELKKGGYAFVEFEDSRDAQDAVSALNDFQIDGKRILVEVTKKSSNGNQNGRDGHMSSDNGGNASGNCFVCGGSGHWARDCNQNREKGSDVRSGKCFRCGETGHLAKFCPNESDRRDNDRGGDRSERGACHKCGVVGHFARFCRSGNDYRGDRRDGGTTCYNCNETGHIAKFCRNPPSSNDRYRDRGGDRGACYNCGESGHIAKFCRNSSKGDRRRSRSRSRSRSRSRSPRRRSESPRNRRYSRSPPRSSGRYSPDDRRGDRFDRDDRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3L7</accession>
    <name>A0AAD5U3L7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">KAT8</name>
        <name evidence="19" type="ORF">HK099_001626</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(2E)-butenoyl-CoA + L-lysyl-[protein] = N(6)-(2E)-butenoyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53908"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:137954"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:53909"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2-hydroxyisobutanoyl-CoA + L-lysyl-[protein] = N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:15921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:131780"/>
            <dbReference type="ChEBI" id="CHEBI:144968"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:24181"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21992"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:21993"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:45949"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000148">
        <property type="protein sequence ID" value="KAJ3223010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3L7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000002">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF219">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="18">
        <location>
            <begin position="156"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="17">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3223010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="445" mass="51308" checksum="93565D3734AB0280" modified="2024-05-29" version="1">MNATWTSCANEEKTFGDSENATVLIGDCSRSAMKYQVPIKGKGFRDMFKKAGYQVWLVNEFLTSSFGPGCKSRTLETFKERQHPNLTNIVKIYLKLDQVAKIIQLRENELTNTLEYYVTFRGMDKRNDQWIKKEVIGKKLNPNIAKIVESATEKKKRNENLKKILYTSNIEIESKTINDSVNTNTFLSENKEGKNNLNSDKLLTRSNVKKLERLKKKKTKSNLSEKSELELAHEALELEREQLTKVRNVESVCTQRCPPGNVIYEKDELKVYEVNGKHHKFYCQNLCLLGKLFVDHKSIFYDMDLFLFYLVTIKGEEGDNLIGYFSKEKDSYENFNLACILVLPCYQKKGYGRFLIEFSYELSKLENKIGSPESPLSDLGLAGYRSYWQTVLIDTLLENDGLSFTIKELSLLTSIRQEDLVTALVGLGFISDLKSQNNIRYEPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4F4</accession>
    <name>A0AAD5U4F4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Myb-like, SWIRM and MPN domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000159</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000102">
        <property type="protein sequence ID" value="KAJ3224168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4F4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08067">
        <property type="entry name" value="MPN_2A_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="43"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="46"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="50"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="6">
        <location>
            <begin position="245"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="463"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="725" mass="83765" checksum="5836E6EAD9DB2AE7" modified="2024-05-29" version="1">MDEIDDASRLLIEQMMAEETHYFGAPTVENKNSFSTSAGRKKKGKVASTRWTKEETEILKGALKVHGEDWQMISELFQGSRTPLQVKNRVNSLLQNGQLTKSEYSEVLDTVIQKIHSSHDVNNVEEDDENIVVGEEVERSEIQHSGIGNHEISNSPVSKKIKLDIDEEETPEVDILDDDEDESYPIKEMIVENFDFNGNSEEKSSDSETKEDDNLEDEYEEESDGENFKNDIVKSKFSQIKTNQVEKVLPKIVIDNSIIQDLEKEECKEFFTKEKHLKYKNKTPERYKLIRNHILSLWEKNKPKYVTKTSARKGQGDVNAISRVWAFLEKAEAINVNVVQKEKLVDPYYSPKGKISEMKASKKNQFLLSSITFSNNSKRLRRVKDDNGKWVDEKELEGKVIDHDELALKTLAEQEKLNLLLSSKIFTKKSKGNGDVDKEDVWNGLDPFHLVPLSKDLKSPFNVEIDKNALIYLDFHSHLATTEVIGLLGGNYDEINKILYVMESYPCRSTSTQVQCEMDPASEMKAREVFSSKGYVVVGWYHSHPTFIPNPSIRDIENQSAYQSLFRREDGIEPFIGIIVNPYQPLEEDTFNESQLISKFSFLGISENWNEKDEYRIPHALSINVKDSANIPDIQSFQHLKNLYYFNKNKDKLEKDISSESTKKELEELENFNFMEKNLIDLNEQFFHGYSKLDKLIFSLNYNFSSANKNDAEKIQFFEKLRKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4N6</accession>
    <name>A0AAD5U4N6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000181</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000103">
        <property type="protein sequence ID" value="KAJ3224131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4N6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="381"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="46"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="417" mass="44782" checksum="B8A10C1648DD518A" modified="2024-05-29" version="1">MSLCGVVLGITFPPCATSTEISETLVSTVPSTSTIPSTSEIPVTSQIPSTTEEPPVTSDFSTPTEATTTSSIEVTTSDVNSSTPTPRNTGSSNVNGSGLSQSTIIVIVGVGCVVGLILICAVIFFATRSSKKSKKRLNSRPNNPVNGSGGGGVGYNYAPAVIPAKENSKPNAVKPFENESTLDPKTTVFNAPAVMQPYAYDHHLYGQQQPQAPFIGPDSGVYPQNNAYPNYPEPNQQYYQQNDPNYYPQDQYQANVQYYPQGNYAPNPYNGQQVYPYYPEGNYYDPSTTSNQLYNQDGNYHGQGVQNFSQSEAAQNYPAYAGSAQPFGSRGIVAGASTDAAVKDENNEVPKYDSGGYSGEDISAENEKELLRLKIAKESAEVKENENVVSREVSNASSQSRKLPDSLNSPAGKKLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Q5</accession>
    <name>A0AAD5U4Q5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008703</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000099">
        <property type="protein sequence ID" value="KAJ3224247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4Q5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="26"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="196" mass="21860" checksum="FE8C98074493D1FC" modified="2024-05-29" version="1">MFRSLITPTLKFQSRQFQTSLKTLEKTLFVRNLAWSVNDNDLNSLFSQHGAVISARVISDRETGRSRGFGFVEMDDEAALKAIEELNGFELGGRPIAVAESDPNAKRSSPGGNFGGNRGDRGGERMKAQIVPIRPTIPPEHTKNQFKYSSGLLNVAVSFFPNQQPFNRRLHKQGKTTLTVMVNMLPTNKINIKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5B0</accession>
    <name>A0AAD5U5B0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_003068</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000207">
        <property type="protein sequence ID" value="KAJ3221812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5B0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000061">
        <property type="entry name" value="Potassium-transporting ATPase alpha chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="960"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="996"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1027"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="11">
        <location>
            <begin position="42"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3221812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1079" mass="120373" checksum="A908CA00D41BF933" modified="2024-05-29" version="1">MSNPETDSPSAVIDIDGSNQKTTQDQPASKTAKKTSKNLDIDEHLLSFEEIQEKWTTQFNPTKPPQSLGLHVDVAAARLTQYGRNVLTPASKTHPFILYLKCLSATFNLLLVLCAIFTWILLIVDPVANFSSNMIPANCSFVRDGNVKQSPASELVPGDIVHVRTGDKIPADIYIFAATDFKVDNSSLTGEAEPQERTNRNTHENPLEATNLAFNGTLAVSGDAYGVVVRTGDSTVLGQIANLTQGESKRESPLSQEITKFVGIISFFAISTAIIFFIVAYLNSTDKPTTGAKISYALNFAIGVLVAWVPQGLPSTVSMLLTIAAKRMATKQVLVKDLQGVETLGAITLLATDKTGTLTRNQMTVTYLWTSLKMVVAESNSESILNPPEVRFDRKISGIEEIINISALCSKARFDRTDVPVAQRVISADATESGLFRFAANKLGDTIDNLEEMYPKVFEIPFNSENKWAMTIHKKSHQNGELSQFIKGAPERILRICSHILVDEALVEMTEEHKNNFTEAYETMAGKGHRVLAFAQNLLDGQNFPADFVFDKEKKNFPTTGLCFVGLTSLEDPPKHGVREAVGHCREAGVKVMMVTGDHPLTAEAIGRKINMMLSDTKERLAKRTNRSVESIGEDEYHAIVIHGERIDSLTDAEWDLIFSKDEIIFARTSPKHKLQIVKHAQSLGHIVGVTGDGVNDSPALKKADLGIAMNISGSDVSKEAAAMILLDDNFASTVNGIREGRLIFFNLKKSIKYVISHSIPEILPFIFNVAIPIPLALNALQVLVIDLGFEIFAALSYAWEPAESEANLMRVPPRKPVTSDSIKQLKERNLRYKDEVDRETGEPIKRNFLQYLLYKLRRPFTRNFWLDFKEKKDGEILVDVNVLSWAYLEAGVIETVGCFTAFYFVLFYSVSNITNKPYQISFADSMKMTSVQPEQTFTTSTGRVLTWYEQQEVIARGQSIYYFGIMIIQMFNLFACKCRTGYPFGIYPLRNMRTWGSLVAGVLFASLIVYTPPFNVAFNTSYMLEPVFWVIPIIFGFILLIYASIRRLIQRKFFPEMNTTEIEGLLMYPTRFSTGSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5G7</accession>
    <name>A0AAD5U5G7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000187">
        <property type="protein sequence ID" value="KAJ3222188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5G7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="80" mass="9223" checksum="45CB3D5378A02174" modified="2024-05-29" version="1">MAITNWSDPIDSAKYDEVMKNKPKIVLIKIFCFFLATCRNVVAAYVTNLWVFAGGDKAAYIAHRVLVMLTWYFLLDLVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U629</accession>
    <name>A0AAD5U629_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pleiotropic negative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MKS1</name>
        <name evidence="7" type="ORF">HK099_006198</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000052">
        <property type="protein sequence ID" value="KAJ3225800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U629"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010796">
        <property type="entry name" value="C2_B9-type_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968">
        <property type="entry name" value="B9 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968:SF4">
        <property type="entry name" value="TECTONIC-LIKE COMPLEX MEMBER MKS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07162">
        <property type="entry name" value="B9-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51381">
        <property type="entry name" value="C2_B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="508"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="539" mass="63245" checksum="33681D8430ECFCE7" modified="2024-05-29" version="1">MPIKYYRTFDQIENLKLKITVEKVSTKHTSILNVFSDEPNEVKLKSSSMEVEWQEKVFSPPEVIKYLNYDSSNSELNQQYHKKVESLGSKKQSKAKKIVSEIADVDNHHKFKKKEVPLHERLRSSCKIDLKKKVEELKFQTPTKNNYKNDTRLDEKYVSKYPIHNKQPLLDNSFIEFNLMIYFPEIQVGQKDLFSEEQEQEVRLCQIKYYPAGLISINPGICSEINKLEHYSGSYTFKMAICSENLTTFDEQKEWEIYEEFFKRYPMMKKVFLRNFFLRKNLISSKIIGNEFNYLAEKYLKKINLFGEIELVKILDPEFECEHLYVRYSLELPEEWEIQNEYVANSKECKITNTAISQRCKPLYNELSGCLEANFGFPLELSLVSKTNAVGSQYPKIYFQVYSVDSWDRHVLQGYGFLDLPKSPSSETITVRTWRPNNTPAEELRSYFVGGSKEFNDLSFIDIPREFETYNFDIVAYTNLGFIAILALTFTKCKNTNAFTGIFGNGQLRAISDALQRARSRLEILRSQKMQEKEQENKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6X9</accession>
    <name>A0AAD5U6X9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_004598</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6X9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF10">
        <property type="entry name" value="SLOWPOKE 2, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="12">
        <location>
            <begin position="219"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3226571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="295" mass="34241" checksum="00F558F1C2B494AD" modified="2024-05-29" version="1">MELIPIENEDNFNDASRADIIHSSTKILHHNLKKGSEEKIKVERIKYRNKRNICRQNVWKRKILGIKDLLNDLTEFFALRSSLFVIINIQEHDSLETTVKGHPYLYQFYGKNKWAYIQRPPGIFFLCVALSIVSLCCSVLKLLFWENGIRNFFRVSYLFGTKFGVKFTNLLHAKNFGVGYTIYVPYFLLSISSVFHLNKLLCYRDLFLNITLFQEQVIKLSYTIWVVITLWEAFYYIVITVSTVGYGDIIPTSVAGQVVAVMLVIVLIVTIPRMTARIFDSLLMEKFDGKYDSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U714</accession>
    <name>A0AAD5U714_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000122">
        <property type="protein sequence ID" value="KAJ3223640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U714"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="148"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="538" mass="63024" checksum="36958A48310E72FE" modified="2024-05-29" version="1">METYSKADVLFDFLVSSISLFNGIGSILHPTDEEQQKLDELSTQGRRLLNKNLPRRRQSLKFHHDDEDKIETKYFCLKTPAIENFRLSLTVYLYHAENFLESATDKDKEFAKIKSSGNELLSKILLTKIAPEKKKINKKDEKECINYIDKLPNEILFQIIIIAGSFERSFKNLFNCLKVSKRWNALTMPRLWMAISIDDLADNFRYTTCMGLNQEAGLTKGFNYTTLLHFPFYNAFELKSKITLNLGAITCSYFPNLKDLVYQNYITVNDVAVILENCKNLVVLSLGEIDFLKESERNYDVESFRDSFKNLKKFGFFRSYSEYADQISFFQQNKFRKLEEILTPFDNFKVLSNCFEVETLTNLEKASLILPPDVQTDLDLLLKYTTNLTWLKLYGHFPLTRLSRKNLDTIKNLKHLKFLLFNSNDKKEGMTFEHDLTFEEILLFLKEVGKNLQSIYIYFPDVVLDDTILIRLSKIFPVIKHFGFMFKCSSVTVEGIKLFLKNLNHINFILDNKFDEEVKDELKRHSCQIYDGETKEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U793</accession>
    <name>A0AAD5U793_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL14m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U793"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000005">
        <property type="entry name" value="50S ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_uL14_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="14680" checksum="571A24F98196183D" modified="2024-05-29" version="1">MIQLKSLLKVIDNSGAQIVECINIMGTRGRIGYVGDEIVCVVKKAKTAEASTKQATSSTLVSKLRKGEVCRAIIVRTKKETLRKDGTFIKFDDNAVVMINKQGQPLGNRILGVIASEVRQKRWAKIASLAPRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7B1</accession>
    <name>A0AAD5U7B1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002913</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7B1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF134">
        <property type="entry name" value="RHO-TYPE GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="F-BAR" evidence="5">
        <location>
            <begin position="537"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="926"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1117" mass="128413" checksum="F3A871384D46EDD5" modified="2024-05-29" version="1">MWYPKLRKIILQAVMSLTIVALIFLYSNDKLNKIKLKNDLKQLLIDKRDQNVLFKSDFDESENKIENNLKEATTNNLDFSENTKDENIITTFEDRRNTDTDSEKLDAADTSTDTKQQKLNPNFKFIWGNRGERDAVVEYQDICLDRNGLFFPTDDNNSQLPRANIAGSADFLDQWFTPASRELKTEVEMEYRDYPLFLLGGVWPYHLSHFFVNNFTPLVNLFNNYFESKNWKGEKKDLYLVKDFIYFDLESLKLTNVYKSTPNIEHNKVVCYSKVIVGLNSTCDCCGCLKDYEDKSVHRQTKDLVLENHLTAEEFQIAMERSNGDPKDRKMHLVVVQRGSNRQILNLPEVEKYLTDNLISYEVAILENLSFTQQLRLFSLNATAILAVHGNALGNSFWMPPESQVIELHSYNQGSAWFEHILSDQNRVDGHRLKYSLIACNNLNCSDRGITSFNAGVSLEIEKLDVILDSEISEVTEFQNITKNRDAFDKNSEVLSSSEVSGNQTQNFENSVENLNDYNEEDIELLNQLCDYENGFELLVERIKQSLYSSKVEIFFIKLQKNFTAESVMFLKKRAVIEEDYSKQMSKLVASTSPNNQLGRDGTFQTQFENFLKIHAKIAEVRLKLSHTITGIAEDLNTIQKNGEKSRKQLKDAVLKYQKSVTESETTLEKAKLKYELSSEEWEKSILLKETFEMSGENPSTGSNFKLPKSVSGLNLFKQSSGKNNNNILKLQRNEEETRIKAANANESYKMQIAKANAIRTEFFKKQLPQFISSLKDTCDEIDVGLQSTLLKYAHEMEAAMMKEALAMSPLERDEVVGSDNLAELGLIKCLAKIKNREDFTNFNLMQLEQNKLHNKPQYNKQNFDYVEFKLSNSTLQLQRQKIKQLQEKLLQEKQQQEKANSPIMPVNTEKSAKSSNNSNKFYFGIDLTEQLTRDNTEVPYVLESCVRFIESENNIRLKSNGLYRLSGNNRNIKKLKALFESGEKINLSECSVNVNDIAGLLKLYFRELPEPLFTKDLYNGFIEASKHDDIRHSLISIHELINLLPDANYATLRYLMNHLWNVQENQVENKMNISNLSIVFGPTLLDFPSSGGEGDLNSMSKVVEIVLSNFSVIFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7B7</accession>
    <name>A0AAD5U7B7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000165">
        <property type="protein sequence ID" value="KAJ3222647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7B7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="609" mass="69387" checksum="9615BFE7F3ABE434" modified="2024-05-29" version="1">MSPLTDVKIVQTSLNNVFNDFFVEAGWGKKTRLTGKILLTIRKPLKEVKMSVTFTGINTTKWISNKPFDIEETKLPLIYSKTFFDICTVIRDPKLLKKSQHSADLLPVKNNENNLLSPLEIPFSLDLPENFNFPQTIKDTKASIEYSLKLTMSWQGNSFKKNLFETMIDVTVLFPDWARTKLLSEESPLSHHLPFSAGKCDVHLDIPKRILCPTEYLAAEVFIKSIPIGRTLRYVDVSLRSTFELKGPHGIKAVVHFGIPLSEDRDIPQCLVEGKRVSVTKNWKKSFKLLVDDTLAVPTVTSQLFSIKTVFRLEIVLDDNPIPNVIVEFPVTILPQQENEVFSFDRSEEGSLSSGTLNDSIAIPNYNLNGKNKGSEITKIQNHSHNRQFRSRSSSPVKNNYSSACNFLPNDNPHVSITDQSLYSSRSSVVDLSSPVFPDNKTRQREIMEDLYSNELPLFHKRGRRPSLAEQKLDDLMLDILPEIGEVRRRSLDVNYSHSYYNQDLKMKFNSNKRKNIDVEESEEFKEERTLGAINEEKNVNCNITTGAPFLQYKAIHAYEPKEYDELELVPGDKIAVKRSYADGWAWGYNLTSMMEGAIPISTMCVPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7E0</accession>
    <name>A0AAD5U7E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">mRNA-decapping enzyme subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DCP2</name>
        <name evidence="10" type="ORF">HK099_003141</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7E0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000003">
        <property type="entry name" value="M7GpppN-mRNA hydrolase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="9">
        <location>
            <begin position="53"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="515" mass="58960" checksum="02841093F0C489A9" modified="2024-05-29" version="1">MFSGLSLGQVLDDLQRLVNYTLMSKIKFQKSIYYKHPRRRISQCRKNLFSNRASSLVCGAVILNEKRDKVLLVRGFKAGANWSFPRGKINKDERKLDCAIREVLEETGFDITDYVNEKNKVERTIREQQICLYIASGVPENTFFETQTRKEIGGIHWFKLNSLPGGKNRHENEENYSHNKFYMVTVFVSAIYSWISKHSQHEKNKKKKTPKNKNQNFNNLKVIDHSDLEHGGNGSDSGFKSDFDYKENTNIEKIINSQDFVDQTAKATQALKDMLGITSNNSGNISTSATFTDDRNMLKHHYGNLNTTSQIHDHSRQLPNRNNLISNSPPPFPPSSFLSEINGNFNSSIQTEDFREVTNFGKKPLPHNKKEMLLNILISGSDRVNGIVNNETNSVYSNNADYCNNGAVQNFHKKVYNSTGNNDYDAKPAEELKALLGIASNPNGSYTNENRYDKVKAQKVDSRIKNTAAVKTEQNEKIEKKILLKKNYNHQKRDKNNTLLNFKFDVEKIMKSFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U831</accession>
    <name>A0AAD5U831_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GID complex catalytic subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glucose-induced degradation protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_008170</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RMD5/GID2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000087">
        <property type="protein sequence ID" value="KAJ3224625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U831"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16652">
        <property type="entry name" value="dRING_Rmd5p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000143">
        <property type="entry name" value="Regulator of gluconeogenesis Rmd5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037683">
        <property type="entry name" value="Rmd5_dRing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF3">
        <property type="entry name" value="GH10162P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="11">
        <location>
            <begin position="37"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="9">
        <location>
            <begin position="37"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00075398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00080744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="270" mass="29925" checksum="F370B8E8BCFD40DC" modified="2024-05-29" version="1">MSAIMKLSKGLEWSAAGELPVEIPLLNSQRYHSIFSCPVTKEQGSEENPPMMINCGHVVAKESLNRLSKGPSKFKCPYCPIESTASQAMRGYATLLTLSGFVFGFSIGIIPAYFGGWFGGKSIGYNHFIYVLGVVTEGGLKLVTLIRIAPYPFGIMSVLLSATSVSLKQYLIAMTIACLKNSIHVWVLLQSMIINCIKVGSTIRELSDFKKSTILRNIENHTLEEREAPSILDFSEVHSETSNSQIKDVDENNLHCRVCDENIRLIHDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U836</accession>
    <name>A0AAD5U836_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U836"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="452"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="264"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="496" mass="57351" checksum="B2D71091E0B4FD19" modified="2024-05-29" version="1">MYQLIKTVEDPLKHEFIPPSNIDTIQFLHLNDERPKLKKNHLILKKDSNNQKKILLPIHFKDKKTVNKVLNFYPRVLKGCSKVFNFEMNHEQDMYDGLAVSQKQAMLVCLNSHRRTRKTLMSLVEKTGKLDLGGHFTDNDLPFETDNLEELSQENKFKFPLIQKSLENLVNSNGDELNHSEDIVLPKEKKILLPKEKYSHLINNKNQELYSISKKKYSSEMDDATRELKKFTIELQQWVADNLETPVNLFPAEQEKLDPCLSEYRSSSVNGRNDSGNRRYSTLKSSKLQVNSSPEENPPIDQNLNNNNHSLDKKTDFDILLNAHKPREIENTLGRGASVRIHASSEANPPLYLLKSLQKTFGIKINSLDKKVEMKKKNFLPDIMKAKENKKKKKIEYGSWYTPPNQWSKMYNDKNKKSTSGKSRRPKINFEEIIQNRAKQDLKVMNSVYQSVPATANSTSETNARESIDEETYNEDKISNELNNSHKPSSVTNEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U856</accession>
    <name>A0AAD5U856_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histidine kinase/HSP90-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006062</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000050">
        <property type="protein sequence ID" value="KAJ3225859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U856"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000001">
        <property type="entry name" value="Heat shock protein HSP 90-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="10">
        <location>
            <begin position="27"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="216"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="520"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="100"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="120"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3225859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="738" mass="84000" checksum="6B9911F195985055" modified="2024-05-29" version="1">MAEKEEFAFQAEISQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDSSKLESQPELFIRITPDKENKTLEIRDAGIGMTKADLVNNLGTIAKSGTKAFMEALSAGADISMIGQFGVGFYSAYLVADKVSVITKHNDDEQYIWESAAGGSFTIALDQGESIGRGTVIRLQMKEDQLEYLEEKKIKEIVKRHSEFIGYPIQLVVEKEVETEVEAEAEETEKAEGEDEDKPKIEEVDEEKEEADKEKKTKKVKELVKETEELNKTKPLWTRNPNDITAEEYGAFYKALTNDWEEHLAYKHSSVDGQLEFRSILYVPKRAPFDLFEQKKKRNNIKLYVRRVFIMDDCDELIPEWLNFVKGIVDSEDLPLNISREMLQQNKILKVIRKNLVKKCIEMFQDIAQDKEAFAKFYEAFSKNIKLGIHEDSQNRTKLAELLRYHSTKSGEETTSLKDYITRMPEKQKDIYYITGESRAAVENAPFLEVLKKKGFEVLYMVDPIDEYAIQQLKEFEGKKLVSATKEGLELEEDEEDKKKFEEQKAAFEGLIAQIKEILGDKVEKVLLSNRIVSSPCVLVTGQYGWSANMERIMKAQALRDSSMSSYMASKKTLELNPDHPIVQALKTKVEADKSDKTVKDLTFLLYETSLLSSGFSLEDPSGFAGRIHRMIKLGLSLDVDESTEADVASDLPPLEEVQAESKMEEDLLELPDVFELLGCSGFALLLSFLSSLTAASLEFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8G1</accession>
    <name>A0AAD5U8G1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8G1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="501"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="405"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="748" mass="87618" checksum="1C5E272DF89895D5" modified="2024-05-29" version="1">MAELCINQKVTDIKKNATLLDFTNFSDRSLNENQKNLTEFVIRMNEFKKSNGVEGISRRQTEEVKRMTSSLCAASESIEEDIFLAENVVFLKSEHAFFLRENEAEYAKVRNRHLTEEKKLKAMHDADLNGRKCRKDAKKFMKDLNRASKLKDTKIHNQENAHRSVVELKLLQSQRHNRIEQEINHTIEKHTEQISQHTKLLEREKKDRKAILELQLTNASEERKIQITLDYQFQSNYHALISKNVLDHLRDQQTLELRQIKEKMALETKSMEAISTLKASSLLNYQKTVFEQKIEYYKEKDKIFSIIAAQKVIQIEEKNKSELEALIIRNRKALNQWKILQKQKFEKKMRLWEMVTGIRADNGKELAFQEENSLTCEVNNGQLNLYCETGDDKLEAVHNDYPKQLQLLATKNNELKQELQDLKKRHFNVLVALKQFQLSEMEEKQKLFQKEEDDLEKLHDDEIKKLLRLQKEELNVYEDIYKNELKIESQVRSVELKALQERKVLNEVFNCIKESVVSINPLGIILRFNSAAESMFNYSALEAVGKNVQMLMTTAHGHNEYLYKYLTTGKSNLGKDAGKKVFARKKEGTIFPMNILVTEVVEDGLRIFTAVCRDLTEVIEKENFKILHEKESLKRVSRLEEELKLEIKRNLNYIQIPKEILEEEKGKADSKHETNNELDIIDNFKWLTSTKIKKYESASLLIGEVVGLEEFQQRDGSKITSVKFLNDLYGYYDMIKEQFGLLSSFLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8G6</accession>
    <name>A0AAD5U8G6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CASP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_000025</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8G6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012955">
        <property type="entry name" value="CASP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057476">
        <property type="entry name" value="Cux_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043">
        <property type="entry name" value="CCAAT DISPLACEMENT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14043:SF2">
        <property type="entry name" value="HOMEOBOX PROTEIN CUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08172">
        <property type="entry name" value="CASP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25398">
        <property type="entry name" value="CUX1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cux N-terminal" evidence="12">
        <location>
            <begin position="4"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="CASP C-terminal" evidence="11">
        <location>
            <begin position="402"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="28"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="227"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="371"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="482"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3228470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="617" mass="72503" checksum="FCC6E42C2F810841" modified="2024-05-29" version="1">MEGFEVASKIWTEINLTVLQKSLDTQSTEILENQKEGLNQRKKLSEQTKEFKKVPDSLKLNEFKNLLKAYQNEIDSITKRSKFAETSYLNEKSKRIEELNIVEAENKKLKEELNELNIKLISSSKNEKEVQTLKERLKNYEAKLNDMVQEKVNLKEQELRLDMNDKIRIYKETEYSLQRQLQQTKDQLITIQNSHDMTQAKLSDNTQKYDDKVAAKLAELDIVVMDFEQSQLKVAQLTRDNELLKKELAGTNDLKNEKLELEEKMLKVQEVEYSRLYTQVEKLQTELSELKSNFSNEKADMLKKNKTLVHETEELTKKLKSMEDYDKLKRELDILKSIEFPDTNFDTEWGEQAVSNVDTSYTLERLMLDRNKKLQNEITTLKMSLNDLNIELEAKTFESAENLKKNEELNKLVKKLEEDLFNLNSVYEKKKISNSNNEKFNEDPLSSIVESMIDTNNVNTPLGLKNSPMFSQTQGNENSSIVPILTSQRDRYRQRNAELEEQIREHVERISELCSKVETLKNENIKLYEKLKFTQSFNYSNSSAGRESVSNNLLDNEKNLYNNNYSNNYEDNYGGYKISRNNNSRQKEDYIQIDNKYKTIYEGSLDPFQRFHKQVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8G7</accession>
    <name>A0AAD5U8G7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000073">
        <property type="protein sequence ID" value="KAJ3225019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00761">
        <property type="entry name" value="Glyco_tranf_GTA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002859">
        <property type="entry name" value="PKD/REJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22916">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22916:SF30">
        <property type="entry name" value="IPT_TIG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02010">
        <property type="entry name" value="REJ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4305"/>
            <end position="4328"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="466"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="PKD/REJ-like" evidence="4">
        <location>
            <begin position="2068"/>
            <end position="2494"/>
        </location>
    </feature>
    <feature type="domain" description="PKD/REJ-like" evidence="4">
        <location>
            <begin position="3483"/>
            <end position="3894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2824"/>
            <end position="2898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="4407"/>
            <end position="4483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2831"/>
            <end position="2894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="4483" mass="488101" checksum="C651EDBB9D21EAF1" modified="2024-05-29" version="1">[encoded data, 4483 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8I3</accession>
    <name>A0AAD5U8I3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004304</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8I3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3228311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="438" mass="50132" checksum="AC80C4A3CDBEA1B6" modified="2024-05-29" version="1">MNNNNICQYFSTVNGCSSGAMCPFLHLQHKPKEDQNEVSFSQKNSSQKVICINFNSPKGCRFGNKCKYSHILDTTSTKDVKVKDRNEKINSESEKNKPVESDSTTSSGLKVVIVKKKSSVLETKNKVQKNESGTQQKVFIQKPIIQRPILKSLEDQLNSTKDPIEQAKLQQRIEIGQIERRFPILKKRNLENFGTELSFNLIPSDPDFPFDLDAQGLQVKLTFDQNYPTSNVKLNVLNKEIPINLIRNIENTFNLKSSRVKMTLLHLVNYLDRDLEKLLSESIQETAISFVSNEKTETKTEEKTRSFVSHPEELSGYYGERRAENSESTTEEEISSDEEERVLKNLNLNTAGKENNKENQHKGIQIKFLELNLVNISLIKCQALNIVVKCLKCKNKIDIKNLIPNLTKFQNCETCNEEVGCRYRQDFIHAGSKKYGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8J6</accession>
    <name>A0AAD5U8J6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8J6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041921907" evidence="1">
        <location>
            <begin position="18"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="434" mass="49744" checksum="340F4B234396416F" modified="2024-05-29" version="1">MNFRLLALLLFTNLTYAYDSYGISERPNIIAKDFRGSGISLADFQNFSNYISDLPTQPPTAQQVARFNNAGDFANRRIAIEEYANSLVNGETRIPGGPIVEGRICTIASDAERSVTGTAKYTSLLESVGHKLYSTGAFYEKANLEFAEGYMESTKAAGRGRQAAFIEKNRAKIDAVKAANAFSEGKAIKTVLNMEAGPPIYESHAKNIMAHSQNVNSVKAYHKLFAEKAAIILSYIYDESFQLLDQLSSNLLRERFKILGETFESFQLLHWNHTPNLDSKCCYEIMNSLERWNFDRNFTNYFNENCNKEIRLKYKVVDFEGKFGYVPFDLSDAGKVSLVTFLIVERSTDFEIYFHDLQIINLFDYVNGYFDTLEFALENFLKDYELQKKENMEKSIDPYWKSYDLEENDVIEKTNMSNKVIVEDDGSDSYWEQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8W1</accession>
    <name>A0AAD5U8W1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000783</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8W1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="147"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="255" mass="28284" checksum="2A2894F5A76E8101" modified="2024-05-29" version="1">MEEINSFKSYLEDLTNIFSIEKELQPLPTFRNRNSHQIDKIQGSNYHIWKNNVEVKKMLRNENNIPKKIVLDENKDSNSNNNTEGNEVNEKENEPVLITIKNKTRLILGVAEYTSKYENGEDADETSALLGGCSSTRINMQYNSTNDEREILKECDLVTSMANSAVHKLIQRGEAIVDIKARADSLKGAGKLFKKKAVNVERDSYVQSLKFILSWDRSCVGAPPGTVWGCGGCIPGTVGCPIGAPAVPPIKLPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB69</accession>
    <name>A0AAD5UB69_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Intraflagellar transport protein 57</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">IFT57</name>
        <name evidence="6" type="ORF">HK099_002413</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFT57 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB69"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019530">
        <property type="entry name" value="Intra-flagellar_transport_57"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16011">
        <property type="entry name" value="IFT57/HIPPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16011:SF0">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10498">
        <property type="entry name" value="IFT57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="203"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="286" mass="33036" checksum="9CEB177DB7468C69" modified="2024-05-29" version="1">MYFSLAIADFEVDAFIKNEKFMVKICGGDLDKPQQFDDPNATVSNILAAAKSLQINFDNGPNKIKQGNGEFVVQLLTMLSERALQIKKFVFQKPSHKTEDFAEEAEVDHEAEVTTENVEEHLFLNQEDDDEDMYVAEIKKKNEERPLTSIMPSVDSSDWKLEVERVSPLLKVQIQNDNKDWRIHLEQISFHYSKISNLFVSTSENLKLLHKEVEKTLEKINSREKYINSQFETQTEEFRVLQEQLSMLKQKHSVSNSNVTDLTTELSRISEELDSVKVSYIAHNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBE6</accession>
    <name>A0AAD5UBE6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBE6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="358" mass="41210" checksum="5E8C6E5773EA87EB" modified="2024-05-29" version="1">MSSPIKTTLSQPSGKQYEFLEEWPGYISFVNNDSTPPRCIQIEVGENRLKLCKKKSPQRDIDDKSWLTFVVDEVKGSDSTDEDIEFLQEDSSPSLIVDNSTENLSLSEVSSRPSSPTSPRSSCNETLFNNRFILPSSSPPQRLECEKFNFNCLTLVPDKEIISNLNKNNLNLNFLPSTPESTKKFFKQKKLNLQLKNSSTKSPLQGSSKYNKNCQKIPITHRKEPEEILSKEKNLRNLNANSENFTSNTTKTAVNNKTFFANSPPSRFDLALLEVAKNRTIRRIKRKRNSFHDDKDFNDEICSSKIDFEIFKERKSQLEDKNICCGSWKPLRELGIQNKKHSFSKRYHVPYENIFNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSM7</accession>
    <name>A0AAD5XSM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Guanine nucleotide-binding protein subunit alpha-12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GNA12</name>
        <name evidence="7" type="ORF">HK099_000629</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001154">
        <property type="protein sequence ID" value="KAJ3206068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSM7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="303"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="328"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="397"/>
            <end position="400"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3206068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="466" mass="52931" checksum="3663CA8C48FEC88A" modified="2024-05-29" version="1" fragment="single">DNFVIVLVLGSADSGKSTLIKQIRITSSNGVFTMGEIDGIGLCDALNLFKSVVNNPLLCKIEFMLYFNKMDIFEEKLKTVPLKKIFSSSTVQDENSYADSLVDEHSTLGNTYEFGNEDGINFTDDSGSNPRKAQQRNKLINKKLKKERKELINTTLIKVLVLGSADSGKSTLIKQVRILNKMGFSMQEIHEFHVVIIGNLIGSMKKIIKGVEMLKIEIPTELLDEYNKSVEIISSYLWNTSVEVDPEVTEMMIKISKMDVIKEGLKRSTELNSLGIQDTASYFVTNTERILDTMFYPNNQDILLSRRATTTVTSTAVTVSGTEFKFIDVSGQKSQRKTWLPYFEDAAATMFVVDISSYDKNMEEESSTNRLFDAWKLFGEIINNELLANTEFMLFFNKMDLFISKIGTVLVTDYLEDYKGNPKDLRDIKIFIAKKFQSITERRLNYVYFTTTTDSKLMKKVISTSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTG1</accession>
    <name>A0AAD5XTG1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007913</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000811">
        <property type="protein sequence ID" value="KAJ3211830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTG1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="28272" checksum="8ADADCB9E6553F20" modified="2024-05-29" version="1">MKFCCYMNESSEQLTIEQANSLSVVVIVNQIGPRQTQSTIRVGSSFLLNKTLHSSKRILVTNRHVLEEALKYAGVLQVAAYDGTLISVTGYYHASDLDLCTLILPYHEMLKDGLSIDEGLKNTGTMVHTWGFPRPYMFFAPLLTVGYVSGFHNQQYYLNMGINPGNSGGPLISSGQVIGVIVNKLVDRTDDISKKIQSLKVVGGMLTMSDGEKHVDIASTIAEAFEFTTSTSQLVIGGAITSDLLKKFIDIVLIELDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUC7</accession>
    <name>A0AAD5XUC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002145">
        <property type="protein sequence ID" value="KAJ3199294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUC7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="194" mass="22935" checksum="911EB39028C108AF" modified="2024-05-29" version="1" fragment="single">ERDDIDLNQFFPLFTKELNDQKNKENYIHWISTKKNVNVKDLKLDNIPFIDGRELFFLMMNQTLFVNELMLNAIKKLKESKRFKLCALTNNFKDPENLFPKLPKRLTKHFDFFIESWVIKMRKPDPRIFSYTCDLIKELPKDCLFLDDLNPNLRAAQKCNLQCIKVSLGNTVKAIKEMESITGVNLLDNDESRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUM3</accession>
    <name>A0AAD5XUM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000479">
        <property type="protein sequence ID" value="KAJ3216441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUM3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="38494" checksum="76E66DA65AA051D6" modified="2024-05-29" version="1">MNSNKNFTYTSVMKNSIQQNSLEVKQDQNLSTQKNGKKSKIVHPYFIQKQLTEQKKKPFNESNLAQNLNSIVSNQYELKNFALEPSSIGMTRPEGSHINPTPYRSVMNNDTNLQNYPSSHLQQHPPYQLPKPSLLIPTTSPKSPSSYSNVTTPSPTQYHAKSKYCTYILESGLQCQNRVSNNNALVGLCYRHFTREPSPQMKPDTPPNRQKTTNHSKTLSTRAATQTTQTNTYSIQTKGAYTCMHPDCANIFPKKYYKFPCLLVSHQKIHSDVKPYTCERCAANFMRLHDLNRHVRNMHQYLKCNHCDIVLQKFEMRSHLKFAHNIKQFGNNQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWC8</accession>
    <name>A0AAD5XWC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Dolichol-phosphate mannosyltransferase subunit 1</fullName>
            <ecNumber evidence="16">2.4.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DPM1</name>
        <name evidence="18" type="ORF">HK099_003102</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 16">Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose = a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP</text>
            <dbReference type="Rhea" id="RHEA:21184"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="16">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 16">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.83" evidence="16"/>
    <dbReference type="EMBL" id="JADGJW010002083">
        <property type="protein sequence ID" value="KAJ3199578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWC8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000119">
        <property type="entry name" value="Dolichol-phosphate mannosyltransferase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398:SF1">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="17">
        <location>
            <begin position="2"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00053724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3199578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="236" mass="26677" checksum="5E4CB02C8FC32C97" modified="2024-05-29" version="1" fragment="single">NSVIVPTYKECNNLKPLTERLFNSLQKYNLDKSTELIIVDDNSNDGSKELIDQLSKYYNVKILVRTKERGLSSAVLHGFSNANASEVLICMDADLQHPPEKVVELIKSLKENEFVIGTRYAGGNSIDKDWPVHRRVISSGARLLVVPLKPMKKQISGFFGIQKKILQKTGIKKINPIGFKICLEVYVKCNIKKHAEVPIVFGVRTEGESKLSSKVIVNYLKHLFELYTYQMPLALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWH7</accession>
    <name>A0AAD5XWH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000201">
        <property type="protein sequence ID" value="KAJ3221925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWH7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="371" mass="41146" checksum="E0E40253D26BBD3C" modified="2024-05-29" version="1">MYSSNTRGSHNNNDPSNSFTLGNSKTDLPVVLTKANLVQKVPSNNNTFSSSRPNKVLKQRNVLTGVSSSKPTSLVANNKTSRSTTTHNTHCINNKKSCSTISIESNELLKPSRLVMSLSSNSPTEIETSSKRTYSSCHINDEVYYESILDRTLRGSSGFSKNMDSVEDKPTSRVSGKVLVSDSGSQTSEDFHQLSFIYRRQSPYDPANSNLQHLEEEMEKVEWSNLTKGSTLNNFHSSRALSIRPSINMEEFFRNDSTQQEDNKNLLSTSPLSNFSNEFPLEPPNHCLKPTPKRGIPGHFLSNMNSASERFNCGSSDGGGSATSSASSFSTMPSNLSSPSAERIQYNNYYFDKSQLPWSNSHLNYRGNAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWT9</accession>
    <name>A0AAD5XWT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptide chain release factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001550">
        <property type="protein sequence ID" value="KAJ3202584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWT9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.410">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43116:SF3">
        <property type="entry name" value="CLASS I PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43116">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide chain release factor" evidence="1">
        <location>
            <begin position="114"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="282" mass="32445" checksum="473D19B5F9ECDFDB" modified="2024-05-29" version="1" fragment="single">MILKNLISLKNTTRCISNIKKKEILSNKISTNLNIINKTTDEIDHILQQIDKISNFKLLQLEYNNLEKLLQSESIWDDQKFAIKTQKKHSELSAKLTEFDSLKEKLFNLRDLAEIGREAQDEVIIQEVVPECEELLESSEKYKLKNMMRSENDKNSCFLEINAGSGGMESCDFVSMLSKMYIKWGENYSSDLKVSIVDELVSEGGFKQITVRFHGEYAFGWLKNESGVHRLVRISPFDDGGRRHTSFCSVTVLPESQEEELSKTMEIPSNDLKIETMRAQVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX91</accession>
    <name>A0AAD5XX91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000916</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001230">
        <property type="protein sequence ID" value="KAJ3205136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX91"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3205136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="558" mass="63933" checksum="C0CD3581F6FE2769" modified="2024-05-29" version="1">MVEHALLISMLLEQQSSLKDQVKILLTKELLEEKEQLSYLNTITNLSSLDSLKQEPTLLKEKTELQISDQTTLAYNEYSSFLAANRCGNNIKEGYSSLDKKLQNFLLSLPELEKSLLKFNQDTQPILEEGKDCKLILSQLPKILDLLEIPTLIHTFIKNGYYEEAMDLKVHVNRRMEAFPEPEIRIVFLQHRNYFLQNLFHQITLNLKKNIELEDKNKKNFSKSGENLQKGNNVSENQIKPNISTNPQLEFLRKYIEASREHFFNIVTQYKSIFSENNQLYFSSNSTECFLDEKSVSVCTNTILSSFVKYNLDQFIEVLEVNVKTLKEVNAINSIMTQTMYYGMSLGRIGIDFRQAVTYIFEDAVGDVVEGIIIAGVNNFIKFAQDSKLENVKKKVTIYDEGFSVSGSFGSLQTILPPSSLLQYPPLAGLLNSYLSAFNQLRVLPLIGLIDRVVLFTKKSLEKIIETLENISSLISEKEQKDEYNNCLYMFSEVLVVDIIKGLKLVYSQGSNAGAKVNLQELVDRLINKKELCKPIEKFVNTILFDKMKEDDLLQKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXM6</accession>
    <name>A0AAD5XXM6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_000156</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000102">
        <property type="protein sequence ID" value="KAJ3224165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXM6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="586"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="625"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="676"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="708"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="741"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="10">
        <location>
            <begin position="516"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3224165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="865" mass="97875" checksum="C4779515715AA666" modified="2024-05-29" version="1">MVNINSDATTAYEDVRDDKSATNWLLLGYVDDKKDDLSLVGTGSGGLTELKTFLKPDQANFGYIRVTVGNDELRKAKLSVHISDVKNVLKAFAIEIAACDLEDLDSKKVDLLVKKAMGLRDWDSQILVSYVTDIILREAMGANTVLVDCNNAIKELLTENPELPSDNIQLTLMEHEKIFLNVEYWPPTTNTLELSQKLGYTKIISGGPIGYTGKIGWYLPEKWVISKPQLESWRAYTSTENTCQFKPNTSLNCGDAVLKPLQQVSDVELSDILNLAKNCENAANSGSDGRRCAESILNGVSHLTHQIEKKLPKGRFNTVKETWTVFDKQIIKSLNLELEPYLMPDFTEQKLVDEMIYSALNDIPYIGYFYTPHWLLSSKSPIKLTSMYIQQIKIYLKYYFRFLPTYNSKCSEALLNGTYNCDYPDTYLYKLVTKKFLEVAPDALTFVQQFIVNEDALLQMLYDKHENSKNLSLSPEMGYWQAACEYVKQQEDSWRRFIPPGYRVKTEEVLELNSPVFIGVQVLYMSNLLITILSGALVIYHRNRAEVKSISLLSLIQILTGLSLTWMSIYANAGPLTLGKCLFKQWNEWITLSVVLGSILPKSYRLFQIFENTNINKPILQTQHLFAVTTAIVLGEALILLGWTFTSPLVPTVTSVNSESYFYQCSSKDLETKNAFIYALLLYNGILIMTTFLLAYKTRNAFERYRESTRIANSSIVITLIALIGMIVLGNHTRSTLTQLFLVRSILIAIAGMVTYACLIGKTVVNIFLSTYLVPDIAVGKGKSGEESSCQDNFESSYQKVDSSQKGLWISYEGLEIFHLNLGVSIKFEDKKGNVTAINFQNHYLKEAFLVQLEKDAKMEPVLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXR2</accession>
    <name>A0AAD5XXR2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000395">
        <property type="protein sequence ID" value="KAJ3218113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXR2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="432" mass="49595" checksum="B98B743064A8C525" modified="2024-05-29" version="1">MLSYFQKEAPLTNENTLQKCLRIAELNETTATLNEETLFLKLELIAQELNLTFDKSVDGDKTTITIFGPILVVDFEFEKDKIKFCKIINSTSQNENNVNNDIDDDTLKNSFTVFFGLEDGSDENFFLNQKINNYFLPTKNVTVPEIDVVSLAGQNNVVYNFLNPKNLTENTFKSHTVLYFEFEPSVVVCSKIGKLILNGIKSFENKDLMDTEIETFDEISKLNSVTELLLMDIKFEGNKRKSLVRLKEGSYLKFYIPANLDDSKGFKLEKISFSSMIQIHEIIKYVRLQIKFNCLIQSCFNEFSFELESKKCLFSVPVVEFVLISNLKLGLKDKTAEELILRIEVGIEILVVLVIVEAVKQLEEAREEEIQENFLKMMTIFEVNESLTESEGFKGKSKIWIYKKIVFEDLAEELGRPISNLVCTSLLALQMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXR5</accession>
    <name>A0AAD5XXR5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001013">
        <property type="protein sequence ID" value="KAJ3208092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXR5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ABC transmembrane type-1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3208092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="54" mass="6202" checksum="8914818C30CBFF72" modified="2024-05-29" version="1" fragment="single">FETVKYYSAEDFELNQYTAAIEEYQKADFISQISLTLLQNIQNIIIQLGLLAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXU3</accession>
    <name>A0AAD5XXU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA 2'-O-methyltransferase fibrillarin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Histone-glutamine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_007734</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50904"/>
            <dbReference type="Rhea" id="RHEA-COMP:12837"/>
            <dbReference type="Rhea" id="RHEA-COMP:12839"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXU3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000452">
        <property type="term" value="P:snoRNA guided rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000056">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000001">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020813">
        <property type="entry name" value="Fibrillarin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003276">
        <property type="entry name" value="PRK04266.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF17">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006540">
        <property type="entry name" value="Nop17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00566">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="21"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3224869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="312" mass="32937" checksum="B8DCB0B42E335502" modified="2024-05-29" version="1">MGFEVRGRGGSRGGSDRGGRGRGGFGRGGGSDRGGRGGGRGAARGGARGRGAPGGRGRGGSRGGRGGAKGGAKVIVEPHRHAGVFVARGKEDLLVTKNLVPGESTYGEKRISVENGDGTKTEYRVWNPFRSKIAAGILGGIDHVHICPGAKVLYLGASSGTTVSHVADIVGPTGLVYAVEFSHRSGRDLINIAKKRTNVIPIIEDARHPHKYRMLVGMVDVVFADVAQPDQARIISLNSHMFLKAGGHIVISIKASCIDSTVDAATVFAKEVKKLIEEKIKPQEQLTLEPYERDHAIVVGVYRAPKKVKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYE1</accession>
    <name>A0AAD5XYE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Mediator of RNA polymerase II transcription subunit 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Mediator complex subunit 13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MED13L</name>
        <name evidence="15" type="ORF">HK099_006591</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the SRB8-11 complex, which itself associates with the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the Mediator complex subunit 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009401">
        <property type="entry name" value="Med13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051139">
        <property type="entry name" value="Mediator_complx_sub13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041285">
        <property type="entry name" value="MID_MedPIWI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249:SF3">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06333">
        <property type="entry name" value="Med13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18296">
        <property type="entry name" value="MID_MedPIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0010">Activator</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MID" evidence="14">
        <location>
            <begin position="1162"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator complex subunit Med13 C-terminal" evidence="13">
        <location>
            <begin position="1364"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="103"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="658"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3225557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1759" mass="199677" checksum="27E70E7222F74B0B" modified="2024-05-29" version="1">MEKEYSFSDSSLTNSFVISNVKSVVWKRYFYISKFELTSEENIPSNNINVKDPLLSTYLDLLEDGIPCLWKLGEYETGTSKNGKPTKLFSNLKNSKLRRKNSLHNISADDESSNTKSVPNHEEKIKPSSKRRSSHEEKRYTSKRKKTNALKTLSSNKSEDNISVIDGTLQYCRELWVFTYGNIKFEPKKYCNIKILHEIESGEFCDEQVNNNISESFVVSESCSFEYKLFCQALKNVLERPIIAVSLSIYYSTSNIIIQPSTTNIILRRLEIGDLDCDNTKIGSLLEEKSPKKGIICKCSSKINYELVLLSPHGIQAFLIPSLNENYKSSSGSLNKFFGYNFENKLLPDTVKVRINDIEGSGCTNSSIIMDYPSYLVYFMFESEDFQDLGDCYRKGYFPTSSFYSVLDQLSNNFNNWIWQQNILISKKTQSDNNTNTEAIKKEVHITDFWSYTAPDSSYSTLCLRECGVTDNIILKMEQKMAALKQSKSPQIKKLKITNLEESTTVSNVKEVNSNLSSHEKVTSIEKLPKEELHQSLTKEALNSSHHNDEMEFMPTTANSDVDLELGLTFHEGDVGDDDFDNFFDDNTVVLQNGDTAASKDTTSPIFSVTQQSPEINTPFVNTPHPATATPANQPQTPHLFHTPSHTPFATCLTPLPISPTAADSQQQQQQQTSSEFSPIVISEEEVLEPFSVKADEFNFKSCYSLNFSTLEISDNEFLEKDTSTILIPQKWSPFTFQQQSNESTKRISYCENSKVDQKIIPQLCFNKEHKDVCEYQVLEPLRFLKGKYGKGGKWKYSPKKKLSEKNCNLINTNSSVLELKKGGLELSTSECDKSVVPVAETSKKKPCIRVWRVDSTLFILNIPPWNEYGTHLNSSYPESNFFSMLCRNLQGLPLFEKAEDGNSTNSGDHLVDLMEEENEEGELIENEVVSFDNISMDTSLLNIIQPEWKRSSRETSTIWDKNFDLAIEIFQQQICFSFITIPDNKMCLKHDAFGKSEAKFDSFTKNGFPFSELGLQLFNKLYGIFDNALCKYDKRTSVNIKGPLTIQQYLDVPGLWISSILYNFFLDNDRNFSKYGGKVQLRKKKKSNEQVVELLSNPQLIFGHEGTLLKASPISLRFWEKLRLEPFGGKKHLQYLAVFPGSNPTNSSLKEEVGEAALDLSIEVANFFYELGTIYQTLQMGKHVPVESKRIEKGMVPVHLLESLQNEPPDSVRMRSYSRAMMDLGVAVTETFENTLAPDFLVIYVIDPFPHRFYSYFDLSYLCVKLLTSAAEAKLQIDHGSNQQLEIERSSLFWLHIAELKRKVIFQIIPIEAILERNAFSGHYPHAVKDICFTTYTRCMDSADNFSSSAPLLNRPIIPPLIYTPAFILSSPNLEIPLYTADEDIVNKTHLIMEPDRILHVAYRVENDWLCACWSDTCGELFESYTFKATSNTDCLKLLWEKTLKVSGVGGFKWRIVFGKYGLCDHKELQDWKSVLKSFIEQSSTTSKESQHEHIEYISSITVVSLTLNSCTKFFDYLPANTNISSSSDVLTPMDTSDLPGSPMVNGESSNSSVFKEQLMEDVPVSHSVVSLNHSVRIFGNEEKAKDDFKRFKYSECSSVPNLIPLVNGWIVDIPKRKDTSRETLLDSESIEVALLFHFQNPKVDSIRSVYPGWFAGSSINSSATGKSLSNLQQHSSSSINVSTANSTPTHFTNIMKDILKQFHYLRFLGITPHTFAKGFLEASSLTQLQSNTFFPVPYHFLIVERACKGLKCIPDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYP1</accession>
    <name>A0AAD5XYP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007113</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA8 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000664">
        <property type="protein sequence ID" value="KAJ3213935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYP1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016680">
        <property type="entry name" value="NDUFA8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017016">
        <property type="entry name" value="NDUA8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3213935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14952" checksum="849C2B5CD695BD40" modified="2024-05-29" version="1" fragment="single">MTTHREGIFVKGLWVEDPEPGYQSTLVEEVGLTSAPLESMSFYFQSYCKDYTRDFMLCKNETNDPKHCLKEGRRVTRCAMDLIGKLKKHCDPEWKSHWNCLDMKNHHFWECRNEEKPLNDCVFNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYY7</accession>
    <name>A0AAD5XYY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="10">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">LPD1_2</name>
        <name evidence="12" type="ORF">HK099_002166</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010000017">
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        <property type="term" value="C:mitochondrion"/>
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        <property type="entry name" value="1-cysPrx_C"/>
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    <keyword evidence="4 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 10" id="KW-0676">Redox-active center</keyword>
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            <begin position="514"/>
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    <sequence length="693" mass="74493" checksum="FB63B50BA44A449F" modified="2024-05-29" version="1">MFSLRSNALKKNSRFLAKPYDLVVIGGGPGGYVAAIKAAQLGLRTACVEGRGALGGTCLNVGCIPSKSLLNNSHLYHVANHEFAKRGIKVDNLSVDLSKMLQAKDKSVKQLTGGIEFLFKKNKADYIIGWGKLESPSKISITGLDGSISNVSTKNIIVATGSEPSPFPGIEIDEEVIVTSTGALSLKKVPEKLMVIGGGVIGLELGSVWGRLGAEVTTVEYLESIGAGMDAEIAKTFQKILTKQGMKFNLGTKVISAKKNSNGKVEVVTEPASGGSQTTTEVDVVLLSIGRRPFTKDLGLIETGVEVDNRGRIVIDSEFKTNIPTIRAIGDVVQGAMLAHKAEEEGIAAVEYIAGGHGHVNYKAIPSVVYTHPEVAWVGLNEAEAKAQGIEYKVGSFPFSANSRAKTMDDAEGLIKVLAESNTDRILGAHIIGPGAGEMIAEAVIAIEYGASSEDIARTCHAHPTLSEGFKEACMATYDKGQLNRNLPLNVLRSSSRLNQSFKRSITNGSFVQARVTKPAPLFTAPAVVNKEFKDVSLSDYKGKWVVLFFYPLDFTFVCPTEIIAFSERSNEFEQLDAQVLGCSVDRKEGGLGEMKIPLISDINKKISLSYGVLLREAGVAARGTFIIDPNQVVRQITINDLPVGRNIDELLRLVEAFQYADKHGEVCPIGWKKGGSTIDTKKPLDYFGKVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZM1</accession>
    <name>A0AAD5XZM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001599</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000147">
        <property type="protein sequence ID" value="KAJ3223024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZM1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="50" mass="4175" checksum="6061EF31A40D3676" modified="2024-05-29" version="1" fragment="single">GASLTSCAGGAGLTSCAGGAGLTSCAGGAGFTSCAGGAGFTSCAGGAGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZX1</accession>
    <name>A0AAD5XZX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZX1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="70" mass="8327" checksum="471DFB0EC3C84475" modified="2024-05-29" version="1">MEIHFLDEQNCDNNLEVLRDTDDIEKRELKETILKILNRDDLLLMYSIKNNLTTTQSNIKLLKMLYGVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0N9</accession>
    <name>A0AAD5Y0N9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000188">
        <property type="protein sequence ID" value="KAJ3222171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0N9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="652"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="692"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="714" mass="80568" checksum="F2C04435D36EF714" modified="2024-05-29" version="1">MSRSNPLLEKTNNTIEINSTHSRSLSFDDIQNKNIKKICEKNIEHDHQIAMDLLVNLFIKYKGLIRAKSPLHNQLRIDVSVKNNDSINNKINYNEVINSSALSIELNTLNDQKKLNLNSNQLNKNETILSSLYCFISTFILPSMFIPIIFYVIPLQNPYDENGYSANWAWAGIILPSACISLSIFPTYLVSTIMGAIPSSTRNFVWRFSSITVSSGITVGFYSILASLSPILFYSIVPTGFPVPLTPLFLGPLVSFVSIYTARYIRLSSDWKLPTENTVNNNKNNHPNTVTFNHIKYIASRINQAVVNISAIYTLSMIASALLIFLFDKNLFLNSNADYNLEKLNYPFVNFIIILSALSLGKFITKKKMKQILTLEGVKRSSQQDISNNENKNIIEHVVIIGTEIWWNLSEILLLLMLDSQTSQVFFVPLIASLEFFYFLFKVLKSWLCLVKPNLDLESDTKSPETVVSIDTFDEKALPSPYSPRLPQSNNRHRTNSIERKGERLRALSAQPNFGSSAQLHDVLNKNHTEIDSSNPTSPRLRSASVKLRHDSEVRSPIKRWQDSSDIASPTRQKWDSADTTSAATLTPTTAVESFPSPTQINSIQLIPIQNLMVKTYLTNITKLTGVLDLYILYAFSSYENQEYLKVTNSNLLLAMITIYSMVALSIIALGFALDINIMNTFKETVLECRGAWMSLGILSTGWFTLWISIHSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y102</accession>
    <name>A0AAD5Y102_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HTZ1</name>
        <name evidence="14" type="ORF">HK099_003236</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes. Involved in chromosome stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2A.Z forms a heterodimer with H2B. H2A.Z associates with the VPS72/SWC2 subunit of the SWR1 chromatin remodeling complex. Also interacts with RBP1/DNA-directed RNA polymerase II largest subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000215">
        <property type="protein sequence ID" value="KAJ3221680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y102"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000005">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="14"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="13">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00063043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3221680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="138" mass="14867" checksum="721629A88B6C2FAA" modified="2024-05-29" version="1">MVKSGKGGKGGKAQQKSKSQSRASRAGLQFPVGRIHRYLKIRTQNHIRVGAKAAIYTSAILEYLVAEVLELAGNASKDLKVKRINPRHLQLAIRGDDELDSLIRATIAGGGVVPHIHPKLQAKPAVHTTVTPGSKHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1E0</accession>
    <name>A0AAD5Y1E0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">MARK2_1</name>
        <name evidence="18" type="ORF">HK099_001072</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000128">
        <property type="protein sequence ID" value="KAJ3223489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1E0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12121">
        <property type="entry name" value="MARK_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.80:FF:000011">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000156">
        <property type="entry name" value="Serine/threonine-protein kinase SIK3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF106">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="45"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="17">
        <location>
            <begin position="664"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="365"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3223489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="713" mass="79458" checksum="2D4ADB3202B8B491" modified="2024-05-29" version="1">MSIPTSKPTINTTGSVTRSDSIDKLAKSRAQSATRPAKVLTIGYYELENVVGEGNFAVVKLATHTLTGEKVAVKIIDKTKLDKATAKKLFREVRIMKMLNHQHIVRLYEVIDTPKELYLIMEYVAGGEIFDYLVAHGKMKEKEARKHFHQIISAIDYCHNLKVIHRDLKAENILLDVNMNVKIADFGFSNQFTPGERLSTWCGSPPYAAPELFQGKEYSGPEVDIWSLGVVLYVFICGSLPFDGSSLPKLRARVLAGKFKVPFFMSTDCERLIKKMLILDPSKRISLEQLKQDKWYTEGMEDQVVADPVSPINISPEEHEAILEELEHAGLEKETVAHSIKDSIYDSFSAAYYLTADKIKKRMKQDNKDRLAQGSLISPVSTTSSRAASPSRIPQVNPLQEVPRLSSTDSVKLNNVLPSISKDSVQDGTLTRVKLSPIERNTKTDVAASKTSTARFAPASGRKRATTVSNGVSVDELKAQIKQSNSSKLVSPKIKPIEPQQTNAAGTDVVPELQLRPRIVQNAEAVRPFSFAGIQSNSLKIDLNKDTNKVIESQINATKPTQAEPQRRGRSHTVHAIVNQNDVSVKSLCSPECSNSSLLVDSGVASNNGTWPKRLRAQKVEPRTLRFTFSVGTTSSKEPEVILQIMKKVLMESQVKYDINLFTATCRFEQVEFEIEICKLPRLSLNGLRFKRLLGDSWVYKNLLTDLIGKMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1T6</accession>
    <name>A0AAD5Y1T6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lysophospholipid acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ALE1_1</name>
        <name evidence="8" type="ORF">HK099_001518</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000143">
        <property type="protein sequence ID" value="KAJ3223117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1T6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047184">
        <property type="term" value="F:1-acylglycerophosphocholine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF4">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="483" mass="55701" checksum="90640CC146930720" modified="2024-05-29" version="1">MKVVHDYIESKLGIPFTQVSAVFGIFLTYFLAILFKFIPNSQPNLKHLFSFFFSSAIFYFLFGFSTCVDLLISPCLVYLLSLKFRTKNFFPILIFAISMGHVSYRHFHSQFLSPSTLAFDGTAPLMVLIIKLSSFGWCLHDGTKPDKELSAEQRALKIAKMPTLLEYLGYLYFFGGFLVGPAIEYKDYYNFVHGLKPFDRIPSRIPSTLKCLSMGLGFIVIYLKFEPIFNLNYCSEPWFDTLNIFFKSAFVIFSMFIARTKFYIAWKLSEGACNLSGIGYNGIDENGTPVWNRGQNIKIRGFEFPTNAKMITDSWNINTSKWLKNYVYLRLCDPRSGVSTSFSTFITNLTSAFWHGFYPGYYMFFGTAAFFILVSRTCRRVLRPFFITTKLKKYKTIYDVTGIICTALSVSYMMVPFVLKSFSSSVQLWTKLWFIGHNPLRDLLNKLSKNDEHVTLNNEEEVNFKGSAREETSKLVKRTKIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y236</accession>
    <name>A0AAD5Y236_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000079">
        <property type="protein sequence ID" value="KAJ3224839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y236"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="353" mass="39920" checksum="E9484F82D4AA2C78" modified="2024-05-29" version="1">MAINVGAVITGFTTPAIVQQSCFGHEKDCYAYAYGQYVVSNLIFNLRTLDVQLLCSLLGIIPPAGVFLPWIVLKCVFSCIFKYFADGRKKELFEYGIDDYTPQMLAEVREVATMFVVLLPAPIFWMAYDQYGSTFQNQYDQLAYIKFGSVEIDSSTSSNWNTIFIIVLIPIFNIWVYPFIEKRFGNFKLLDRMLVGMFLTSVAFISIGILQKFIDDSGSLVLDPESNALICDQANPGKCLSGWWQVIPYFIIGVAEILFSISGLNFTYSEVGSSMKAVSSSLWLLMVSIGNFLTVLIAVWYKTLGPQNFFYVNAALLFGAMLIYFFIRTQYVYKIDRKSVEQSIAVGEEKLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2P3</accession>
    <name>A0AAD5Y2P3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000076">
        <property type="protein sequence ID" value="KAJ3224927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2P3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="335" mass="39630" checksum="409B72BA6130BB07" modified="2024-05-29" version="1">MKGQKSYTNTCKVVTRPFSFLEKRGEDAIFTLNSDLNKKIMAKFQNGEKNFLFKDLNENNFFELKKSIEDKLHKCKRYDNLLDTRRLMYLEECFELAIPRFSQFRGLLTEIKKVYANALKNNLYTEQEKLYLKSKIQNLLFETGNEKAIINQQNINKELVESIRITKNSNLMMAIKDREDNVKFVRIIGKLYDYELLASTGNEENTEALKLRGRWEYILSWLEERLEKFPNSYLNGLLENMKNHPEFYRPFFLGINQMDADQIIDPELFKLKLKLEEMHSMIKSVKEALKSFDEQILSSELKLKEREEKNLDLKVLLDSLKLKIAKKEADLLAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2R6</accession>
    <name>A0AAD5Y2R6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NIF3-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000072">
        <property type="protein sequence ID" value="KAJ3225067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2R6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1390.30:FF:000001">
        <property type="entry name" value="GTP cyclohydrolase 1 type 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.30">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="NGG1 INTERACTING FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799:SF13">
        <property type="entry name" value="NIF3-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="DUF34_NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="NIF3 (NGG1p interacting factor 3)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602678-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="31059" checksum="39D54283ABB0822E" modified="2024-05-29" version="1">MLANVTRTMEKIAPIQLAEAWDNVGLLIETAAVNKKSKSVFLTIDLTNKVLNECLQYPDVGLIISYHPPLFSSFKRLTMKDPKQAIAIRCISQGISVYSPHTALDSCKSGINDWLGKKLGSGTLKFITPVKENVLKNLTELNYLRENEAELVGSGRILTLDNSVSLNELVAKVKEGLKLKHVRVAPKDSDLDLIKTVAICAGSGASVLLPVKADLYLTGEMSHHEVLAANANGTSVVLCEHSNTERGYLTEVLKPKLLELFKNDKLDYNVIVSEVDNDPLSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3C1</accession>
    <name>A0AAD5Y3C1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056748">
        <property type="entry name" value="VPS13-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009543">
        <property type="entry name" value="VPS13_VAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25037">
        <property type="entry name" value="VPS13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25036">
        <property type="entry name" value="VPS13_VAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Chorein N-terminal" evidence="4">
        <location>
            <begin position="8"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="5">
        <location>
            <begin position="1853"/>
            <end position="2407"/>
        </location>
    </feature>
    <feature type="domain" description="Intermembrane lipid transfer protein VPS13-like C-terminal" evidence="6">
        <location>
            <begin position="2911"/>
            <end position="3018"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3044" mass="344736" checksum="F3BBC04C82AD55C2" modified="2024-05-29" version="1">MFESLISSVGIWSGNVVLNNLKLKTSALDKFNLPINVSEGYLGNLNCTIPWNDLKNKPIKIEISDIYILAVPKLGQDYDYQEEFDSELKHKFQRLAQAELLTKEKAEVSLKDQSFVTQLTAKIIDNLQFSIKNIHIRYEDKINVPESPFSAGITLSELSAISTDSLWNEAFIHDLSDGINKYVKLGSLAMYWNTELESLENLSGQDAFDAFVKLIASKGQNNNNNLQYILRPVCGIGKDYVPGSARNFAEIEFDELGFELDDDQFNTGLALLNAFELYMRSYKYRKFRPPRTVPPAADPKAWFKYAGNCVLFDVHEKNRKWTWEYLKERRDDRISYVNVYKLSQTMPSLPINESALLFQLERKLSYQDLRFYRSIARNQLRKKKLEAGPVEKVTEKVSTWSSWLGWSSGEQNTEDEKEKNNNVFTQDHMKQLCETIEYDPEAAFTSSVFPDDAVLFNLSWLLNTGSLSIKSGKRSKQPKELMKVIFSKFSANILKFAKVGSYLADVSLQGMECIDGTTSSKVYTHLVKAKQAVKGDSKFFQMVAELKPLDERADNAVQIRMLPLEVVYNPAAIKSLVSFFTPPSDNEIESGTQFTTLKAAAQNTFQGITNQTRLGLEYAIEEHKTLDLKVDIDAPVFIFPENVNDPESTIVVLDAGHFLIESKLANKVLLKDISQKKTQLNEHDMDQLKSMLYDVFTIELSSVQVLVGNSYDACLNELENQSSTFDLHFIERVNIMFSVHMCILPKETAFTWMKIFGELPRLHLNLSDKKYKSVMKILDSISGGLSSDEATHMSSSTKTTVQLSKEEWNLYSQSKIQHSDADYFSDDDFEDANEEFVSEENEIDEKKVLEELPSLLTKSQDISELAKVLMECSFNVGEVSISLKRSTVDSISAETELAEMSVKLFQLKYTNRPLDTKILVQIASAEIEDKIENGTDPKFRYLLSKLEETSTAENSNVEHFIYLSYESIKKVSPDFHGVDQKVDVTFGALNVVLTRKSILDLYDFLLTAFVSKEEKKTILPPEITEEDAMTDPLSTASDMEESTFVVSTSLKSINLLLNRDGTHIATSSFDDGQISVVMKNKTMKVNGTLGNFSIVDHLVRPSAKDPSIYRDFISVEGGQVADFVFESFDISSDNYPGYDSSLNLFAPSVKVTFLEDFCIELQEYLSEFQKMHALVESARKAAYDKANHMQESGGKFHFNIQIQTPILVFPEVSLSSKNFISMYLGKITAKNNFSEASAEKYGSENAIVIDEISARLESMKLISTFDNENESGVGTSEETDILEDVHADFNITRFNINGENITKNSLKVPDLQVAIKMSPVQLKLIRKQYILMLDLIDSLQHAFSSDDGRDTSSFSKMDQISEDVSKENVQDEKRSTMDFLFELPKITLEIFQLLENKESSLAEFLISRVFFKQCTLLNGTSKMEAEIGALKIFDTRQTDNIFKDVLRTITKPDQSMLSIQSTSEKSKATNYLITFDSPKVTLILDHIFAIGNFFADEKKRAKKPRSKRNATVKDIDDGLIDLKFAESPDAATPTDSIYRVNVVDLEIIVLQNVKVASTEAIILVLKHLVIAHDGITSYSAHDLGMFFCAMDQRAETALRFIQNFDLALTVEDAKPSPGHKLTDIKIDVTPLMLRVSYKDVLLILDIVNQISELASSNEKNENFDEKGAQEVVPINNLIMSRETLKLHTQGLRLILIDDLNDLHLPMFDFIVDRVGADVKDWSTQMEVRVALSMQVNYFNIKNSHWEPIIEPWSCSLNTTKTSEGATAITFSSKKKLEFNLSHIFIETALKTFNRWDKKDERKLSIRRKVHAPYILINRTGYDMHVWADGTTNGLDTEFKLLSDGEEMSWRFGDWRVLRESTTASPNKISLQISGPAWESLKSIAVDREGVRSYLLRPSIDQVSHQLVCEVTLKDNVKVVTFRSSTALENSTNVTLEVVTINSAGKLTSKIQEVLPGKDYAVPIITSYFDKLLIRPKGFGYHWSKEVLFWKELQRDNFYPLVSSFSPDRNIPPFLFQVNSTFEKGEYPKIRMKILPPFQFENLLPYDIKYQLTDKTKHQEHKQQLASGKLDTIHTLNPTHFLVLRIQILGTDYRESEVAVITNSDLGYRDENVTLKDHEGNTLMLRIKYSNKLEKGGRKVTIYSPYVILNKTGLDLKFSASSLMSQQRLAAGQVSRVHNPEKVEPLMFAYSNFDTVRNRAQVKLPDSDWSRPLSFEAVGSDFDVAIPLPKRNKSVHLGISINEGEGKVVKKIMQKLVTVCPRYNIINEMSEDLNFRQHGSNAVTTVQAKSSLPFHYLELFEDPVLLSVRRTGLLNEWSQPFIVNNIGKTFVKVGKVGGSEEEDLLNVEIVLEGAAIFLIVSRNEGHWPFLIENSSEQDVVIWQSGSNNNYIVQKDSKKRYAWDNPSAQNKVLVVHVNGKEREIDLLDIGNITHVKYPVDMKGSQYKVLCIQIVAEGPVLVIRLSQLPEQYRRTADPSTASSSDSLMLSQKDAEVALFSFRFRMEGVGISLINQHMQELLYASFKDFSFTYVDGTTIQKLEFTLKWIQIDNQLYGCIEPIFVYPTNLPKDGDEQFRPVLLGTLTKSKDISYGLDYYHFCSILLQELSFDIDEDFLNALLEFSKFNVAGWEEIDGKLYDPEMVTPHHQVSDGDVRMYFERLFLQPIKINVSFARTKTSNEDSRPRSHNILTFFFDGNERKDSIFLIILVFTMAIGNIHDAPIRMNSLELHHSVVTFQQLVNSIMTFYSQEAVGQIHKVIGSADFLGNPVGLFNSVSSGVWDLFYEPIQGFEITRPQDFGIGLAKLLEASARAYQLLHWTMKNKPKHAVSGVTQGVSSFFGSIGSGVEGLVSKPMEGAEKEGVSGFFKGLGKGVVGKTIRAITKPVIGVFDLASTVTEGIKNTTTVFELDLDRQRLPRYIGKDGILKPYDPREALGLSYLKAVDNGEFFHEDYIAHLDLRNEDLLVLVTNLRVLMIRIKKLRYDWNLPYSDVQLIRLESGGITLIQKGNRQTAKAKVIPCPDSNSAQWLCSKIEAAFGEYISRHKSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3M7</accession>
    <name>A0AAD5Y3M7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3227011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3M7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053275">
        <property type="entry name" value="Agnestin_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38688:SF1">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38688">
        <property type="entry name" value="PYR_REDOX_2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="44391" checksum="935EEFB37255690A" modified="2024-05-29" version="1">MSTMREISVIGAGPAGLITVSRILDTDSTSKINWFDPSFKGGRLQIYSEVPSNTKVSLFIQFAKVSNSLNSILESTSSEGGKSTELEILQSLDQDKGCNLKFAQEFCAFLIQQLRIKFSNRINCFEGWITDINYKPNENFDLCFNSGAVDNFKSDVHLTNSEAKLFSNQSKLFLCTGSEPIPELVSRPHVKFSKSNPPKLLDLDVALNPSKLKTCLSKENVVAVVGSSHSAILCLKNLSELKDRPKIVNFYLSPLRYAEYKDGWILYDNTGLKQMAATWAKENLSSDEKALKIGIQRVLVKDEAKTYSEHIPEVTHICYCVGFKRRFLLKIKVNGVEVETLYYNNKTARLILNGKELNNGYGFGIAFPEEVVDKVGNVETSVGIWKFSNYIKKVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3Y4</accession>
    <name>A0AAD5Y3Y4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3Y4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="16272" checksum="B581A7D68FCBD9AC" modified="2024-05-29" version="1">MSNLYLSFLIVWIPCTILRIWDGVTVVKPPEMLLTLVVVFTPLGGFFLSMIYFYPQLFIRKQKSIEQETETERCNVSDAVGVIGDTFLKRNNNSNIKKYTDQSYVNNNLEMFDFNPSSNFDSKSVSDNSLYSFESGPSYTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y460</accession>
    <name>A0AAD5Y460_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y460"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="386" mass="43268" checksum="A27074CCE6D24024" modified="2024-05-29" version="1">MDFGSLFRASKFCALQKDQVITTTLQNVKKGDWGLKSTRPKNVPSNFSIVKSHSDKSKRLIVSSGFLPFSQSQRWKENFIFPEKKHDLPILPTNLEAEILNNSNNFSGTKSDDLKEILKKNNLKSLPKFDTFPKYIGDLNQKEYDKLILMAKKLRKLYLDLVNAKLLDPKDWNKLLNVTTKPKAPFQANGSGSSFFHPPSYLSKEVILTNLSTVQKEVPDFNIRKIMARPVRGRILSKVNGGHAVGISGFVAFCATDHLPYGQGRVAAGVNRDNLMDFWVLEARINHSGQPEIYVTGKEPGAESAYKNSNDTISFTNTMFGRAAENKVNKVDGNVNEKDQSKDTVKNLLNELQMTSKGKSSGTDGKGKKKKVDEIDFELLFGDKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT55</accession>
    <name>A0AAD5TT55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001916">
        <property type="protein sequence ID" value="KAJ3200391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT55"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="168" mass="19725" checksum="50106709AF9CC140" modified="2024-05-29" version="1" fragment="single">YELIRPFGRSDLPEVPKYPENERKLPVLVNYKSTVQFTKILDDFQVKYKLLPKKYGGPTALKQFKAFISLPYQVSTMKLYENLAQGVVSLVPSPRFLRILMSQPQFDFTPSSTTQDLGINFWFKFIEFYNKDLKKFYYTFDSVEELKEILESVNFDAEGRGAKAKIFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTU7</accession>
    <name>A0AAD5TTU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Proline dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001259</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proline oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2 5"/>
    <dbReference type="EMBL" id="JADGJW010001338">
        <property type="protein sequence ID" value="KAJ3204122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTU7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF0">
        <property type="entry name" value="PROLINE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="7">
        <location>
            <begin position="100"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="381"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3204122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="515" mass="58104" checksum="DD88AC1128886884" modified="2024-05-29" version="1">MKRTIAHGHLVKKQSTITTQLHLAQPIQSSNLRPHKSKSSLELINSLAVFKACSIPALVNNSDKILDIFEKFKLTPISNFIIKRTFFKHFCGGENLNEVLPTMQKLNKSRVNSILDLSMEADLEAGAEKSLSSAVSEAEKIIEMFKSSIDISSTQPNAFIAVKVTALFPPLILLRWSNTLQVFKSKFMNKNTFTSTEFVNAIGGDKALSMKIFNTLKKNSDGSVDVTSITESIDVIYKESRGILPMQHNSPAASRSDFELLRNEDLEVIDAIVPKIESLCKYSLSKKIRLMIDAEQTYFQHAVDSVALHCSRTINPKNEGGLAVVYNTYQLYLKDGLKRLKIDVERAERFGYTFGVKIVRGAYMVSERERAEELKIEDPINENIEKTHKDYNEAIEYLLKKVKFNPNISFVIASHNKTSVETALRLIKELDINLEEKKNHFGFGQLMGMQDGIAFYLGEIGLSVFKYIPYGPVNITIPYLIRRAQENSSLMTNSGAVQDRKELLEELKIRFGISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTW5</accession>
    <name>A0AAD5TTW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001491">
        <property type="protein sequence ID" value="KAJ3202998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008709">
        <property type="entry name" value="Neurochondrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109:SF7">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05536">
        <property type="entry name" value="Neurochondrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="382" mass="45012" checksum="A9576A653D73CD2F" modified="2024-05-29" version="1" fragment="single">KKYRSKKCLDFILKFFSPVKQIDIKYLNYSIAEIANQFKMEDTLFKFDLLKVEIVLLLSVESYISPDRTDNYSWANDLYFGLVQNFRNKLTIEQRDHSLTLLSILLKKFNHSILEDDLKSALLLLHISSAELRVLLEEVDRKTADNKDISERWKHMLPITLELFKSFTEFAINFSEKQLNSNKKFKDTEFDFIFSTKKILIETVLDMIYYLNFEKNNNSGNNNIEIRLFCIKNCSHYLAEDIEGIEVNVLEDFLIIFIDMADKPNITPHPYEFSTEFLDTVTTSTEHLKIFIDNGGLRSIKDYILNKKNINPELEQDLINYLLNALILTKDPETLTKFQILGDLLQFLIEKKKNEKFEFSVQLAVFSTFFLFYFQKVQLTDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUX4</accession>
    <name>A0AAD5TUX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001034">
        <property type="protein sequence ID" value="KAJ3207764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUX4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="68" mass="8144" checksum="DEB759B7394A5861" modified="2024-05-29" version="1">MFINDKRERVIKVCRDITILSKRTIFLLHRITQTDRNVVLTESETKLNELKVLFLRVSNELQGNSYHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVE4</accession>
    <name>A0AAD5TVE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001745">
        <property type="protein sequence ID" value="KAJ3201329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVE4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="137" mass="15818" checksum="AFEEFCE7DB25A622" modified="2024-05-29" version="1" fragment="single">QYILCLKKSILLDLETTTSNTSQSSNIEINDEKSVNKKFSFGKKNRKYQNWDPNELKISGKTYVKLNNLHFIPTLFKEIFKKLPDQLNTTNKIDDILNVDRMIPTNEKSLPKTPPEPPLKDSLLLETKIPWVGVEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVU2</accession>
    <name>A0AAD5TVU2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF659 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001325">
        <property type="protein sequence ID" value="KAJ3204220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVU2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007021">
        <property type="entry name" value="DUF659"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04937">
        <property type="entry name" value="DUF659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF659" evidence="1">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="291" mass="34184" checksum="DAD6FF1C97539C54" modified="2024-05-29" version="1" fragment="single">GRKDAKGNYVYACLIIGHNDFKFYLGNLDFNPDLHNAENIFNELEKKLKEHDIVLERIIGIVTDNLPLMVTLKNIITEKYPHIYSLRCVSHDFNTITEWCLNFDEEKIKDVKIHCKQLLSYFSDSQYYAEVLSDWPKKNKVKLGLEMYSDSSWDSFLKLFQCVEAHKERFSPLNRMSVKTLEMLAQTKWFLLEEEKIEKKALFKIEIKTKIQNPNLDNTVKDDPTNPLENLLDEYNKIEIFSKLEEEKNEEIVDSQAIMLNENLEDIFDFSLLPEGEDDVDIMASVVAKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW04</accession>
    <name>A0AAD5TW04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UBL3-like ubiquitin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000794">
        <property type="protein sequence ID" value="KAJ3212114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW04"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039540">
        <property type="entry name" value="UBL3-like_ubiquitin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13881">
        <property type="entry name" value="Rad60-SLD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBL3-like ubiquitin" evidence="1">
        <location>
            <begin position="5"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="69" mass="7118" checksum="90D1EC8D706B9C39" modified="2024-05-29" version="1" fragment="single">FGIDAPSDISKLRILHLGRMLDNSVTLEASKIPAGQATVVHLLISGNGASNNSAAKLEKKSGGCSCIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW94</accession>
    <name>A0AAD5TW94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MED14_2</name>
        <name evidence="11" type="ORF">HK099_007607</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000750">
        <property type="protein sequence ID" value="KAJ3213066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW94"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055122">
        <property type="entry name" value="Med14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013947">
        <property type="entry name" value="Mediator_Med14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809">
        <property type="entry name" value="MEDIATOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08638">
        <property type="entry name" value="Med14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit MED14 N-terminal" evidence="10">
        <location>
            <begin position="36"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3213066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="711" mass="83044" checksum="30F303F7BB8EC2FD" modified="2024-05-29" version="1" fragment="single">MVEMVVDIEDGPLNTNQFFKDYFTPEEQESFDDQFLTISYLIEIITLKSNYKLLELSEKLTFLSHTDRKKQILEHSIFERNQFAKLLVLIRWAKKAAYDTIECQRLLVLQDKTDFCFSTSADMLYNTFLQLHLIRDPIYDVASSLEFVAEATNRTRLSNFENKAHEIPAENKNLLNCQHIDELLRRKLFFDEVLPIEFKRGMKIEYGLAEFTVKNEFQVILKYITDAEEPWTIESFVILVRSKGNLYENIPSYMLDDAQINAIRKIAKNLMYDKVKIEGNNTAELFPLVNLYHFLHSFCLSYQLEILHTQLTFLMTTRWQDQLFVNFDRMRSLINVSYWRCEKKLQSNDFRSSKNFLEFSINEKNLDTKNTKVEAVNNNSVLGFFGDEIGSTKKISVKGFTLNLTNEIISGTQQLNFDECECQINSAEVDAEEILFYITKVKAKEIIQHLFKILKSCKIAPKSSKSIFFAGFNESNIILTDMNYPLMKEENESSPLSEIKLLVQYLPDRLISCSIELRTGNIVLKQFNFQTDLEISYLKELEDKLNLNLDNAVEAFLEFRCKIMLERITLMATKLEFDLVLGLPVEEIDMIVDPETANNENKKINLNRIFLKFKLLENFYLVVDVYGTTADYLSLKDKLKELTTIEISEGCLFKVFLIQIAPLSLENNPKYDIVRSILINNKEQGFEKEVGFNEYFAKITLDFLFRIQEFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWB7</accession>
    <name>A0AAD5TWB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000754">
        <property type="protein sequence ID" value="KAJ3212991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWB7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="2">
        <location>
            <begin position="192"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3212991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="301" mass="34885" checksum="4ED73E43F36B60D2" modified="2024-05-29" version="1" fragment="single">MEQTLQKLNMEQNQQKLSVEQTQQQLDEVKADIKKIELSIEENKLEKTQVQLEKTQINIFITEYTTKLNKTILELLAEKDETFLYLDKERRELAERLSELDKQRGKLCDSINLLYDTRNLLLKEPVEYKRIEEIKALAFESGSSISKPSFESVGKTGCIYPSKQSSQSSRSSRSSKTQEEFRKIVIARDKVCIISESVEAANCEACHIVALKDKEHFDDYCKLFEISFPPFMDSDSTKRLNSVCNGILLSPSMHRLFDSHYFTILYSDGKYEFWCQNQDLLDKVMEENPGVKLLSEKNGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWE2</accession>
    <name>A0AAD5TWE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucosamine-6-phosphate deaminase</fullName>
            <ecNumber evidence="3">3.5.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_008101</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible conversion of alpha-D-glucosamine 6-phosphate (GlcN-6P) into beta-D-fructose 6-phosphate (Fru-6P) and ammonium ion, a regulatory reaction step in de novo uridine diphosphate-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc) biosynthesis via hexosamine pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000857">
        <property type="protein sequence ID" value="KAJ3211074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWE2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006043">
        <property type="term" value="P:glucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000002">
        <property type="entry name" value="Glucosamine-6-phosphate deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01241">
        <property type="entry name" value="GlcN6P_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280:SF5">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="11">
        <location>
            <begin position="8"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="350"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00050047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3211074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="656" mass="73273" checksum="CB1405A2EDE2F3D7" modified="2024-05-29" version="1">MRLLIREKPDNVADYVANYIKKRINLFSPSEERPFVIGLPTGSSPIGVYERLVKMHKNGELSFKHVISFNMDEYCQIPQDHPESYHTFMWNHLFKHVDIKPENVHILDGNAKDLQQECLSYEEKIKSVGGIELFLGGIGPDGHIAFNEPGSSLSSRTRVKTLAYDTILANSRFFGGDIEKVPKLALTVGVGTVMDAREVVILITGAHKALALAKCIEEGVNHMWTVSALQLHPKGLIVCDEDAVLELKVKTVKYFKSIEKVHELEIKSIKSFDVTPTEPVTSQSSVSNGFIPVDVINLIPTRAVTDFSQVTNSEFIPFAKTSLEQPSPSMMAEPTFSSLTVDFQREFLSATHPPSTSSPTSTQQSRTSTTDNFINPASNSLSKSPLTLLPSTSTTDRSSETKVEVVKSTTSFGFTPYTSSSVQSNPESKETSTTSTASFITGMVFLGLLVFVALVFTLIYFKRIRRERTVAFSTGKCSKAHSDVETICPSTNTTATRALTTLPGEHPFLNPHQNLDRPQNSFLTPYEHFNDTDFNNQSPFYSSQEINNNQYHENINNQINPFELQNIASDYRFNDINYTETSPVVEQYGSYNKDSFYNSLYNTYESSESKHMSNAYSSDFGSESDFNNNGQLSLLGTDKELNKRESEILNTYVRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWI3</accession>
    <name>A0AAD5TWI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000835">
        <property type="protein sequence ID" value="KAJ3211427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWI3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319:SF35">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN PMPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3211427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="561" mass="63904" checksum="CB758007070B4281" modified="2024-05-29" version="1" fragment="single">AICNGGKDILAKQSFWVDIKLSNSTPEFFECTGETCCDKENGCELDKTCSPDTSGPLCEMCVDGKSKWSAECFECDGPNVTYFMTDVQNLLSGIASISPEIAFNLLGGNLTKCLTPLTGSAYYWKKSLNNESLIVKKFNTYLPKKMRKKTMESFKASFLEILLFVYEPLFEHAITIFDCRLISFDGEKVRVMEAYPDIICYRGNHIPLIILAGILLLVLVIIIPATLTYLIYKRDKSPNVTSILQKDKDSDKHNDEDNLSFIHAIIEEYKPQFPYWIIADFFVKMTITTVSVATKYIGDDVHSYAMFIILLLYLITVRYKVYKVELENFCNLIFCASLLGVSGLGIVKNSVCGKEFKSCAEGNLPGFNNLMFWQYSLTLFPLIILILRAVSSILHFAKIRYSKFKGKPVNNVKQNYFKDSEEDKNLIPTKKEENQLQNYEQKVIGIVKTAELEKPGFVNNDNQEVPSTKLADYEENNDQIPRTGNQKIISSFEKSRHSDEKNQLLKKSDENQESSVLIEKSQHDENNQLRPRNSNIQGRPSSVREPIYSENNIIGFRYLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWK9</accession>
    <name>A0AAD5TWK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000813">
        <property type="protein sequence ID" value="KAJ3211801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWK9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039461">
        <property type="entry name" value="Peptidase_M49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422:SF11">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE III-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3211801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="297" mass="33927" checksum="66938F4C265CEDF1" modified="2024-05-29" version="1" fragment="single">MKVAAGQVSHQATSLVEFLLTVLSKAEDGKKLANLDTLKKKSGVTEKDWENFLLYTNQTLANCGNFRSFGDTKFIPRIAAEEFKKIVESSENHEAALKSFNALSQHIYSLEPETELLIGFPGDGYVSGYYSNNIKKEDVVFTNEFLISQNLIELNTRLNKSVKDNVNHYEIKIASAEITHEPKTYDYKGTKITVVYGDFQKEMKDIADNMEKAGEFSANEHQRKMCEEYVKSFRTGCMQAHKESQKHWIRGKFEFNHLLKIICFLDLQPHVESNIGFVETYRDPSGVRAEYEGFVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWL6</accession>
    <name>A0AAD5TWL6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007408</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000714">
        <property type="protein sequence ID" value="KAJ3213412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWL6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004868">
        <property type="entry name" value="DNA-dir_DNA_pol_B_mt/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03175">
        <property type="entry name" value="DNA_pol_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B mitochondria/virus" evidence="9">
        <location>
            <begin position="32"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3213412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="86" mass="9730" checksum="B68970F2EF3427D3" modified="2024-05-29" version="1">MSKIIKGIKLYKESNIIESVNFGSNNIITTNIIIPIGKRKYNEDIRQAYYGGHTDVYKPFSPTGKAYYYDINSLYPASMLKAMPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWV1</accession>
    <name>A0AAD5TWV1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000763">
        <property type="protein sequence ID" value="KAJ3212805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWV1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="155" mass="17922" checksum="19B6C5C434BF9878" modified="2024-05-29" version="1">MEINEETKPGYWSQVFNLNNKAFKRKRGVSNELSLTGMIRTDLVGISVNIDPPPTKGRRIDALDTEVYLERNTVGLIKENFVVIDPNKRDLLYCLGSNNHKLRYTQPQREMETGKKKYRKIREDATLNQRCKVDSFFGGGDRPFPFLRSNNNIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWW0</accession>
    <name>A0AAD5TWW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000726">
        <property type="protein sequence ID" value="KAJ3213300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWW0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="322" mass="35896" checksum="F91FDEF7519F6C66" modified="2024-05-29" version="1">MYSSNYVKSECTSTNSDQLTLVESDDCLAATDSEPDEMKDDFTFKQSPSTFNSNFTILSEPRSDFSLSTATLSSSSSNSFVNNNCSSSKASTLNSPILAQNSPNSKPFKKCSYLNTPDFLDTGPDFNLTSNILPLSYECGSPLRMQQIFSPPPTTTQIRDVAISSPESTLSSINESFFPPTPDLQLPVIPSTRELPINFNLCLKDQNPEPNLTDSCQNHAKDQGLSNSICGLLNSLVQEKQMLHSYNFPQRKINFNMGYTMSKCDNTKNTNISEVCQPEVEKPFSRVSKFDVFNFNTYQNFATYPCEMDLKQFLDSVTQSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX50</accession>
    <name>A0AAD5TX50_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000677">
        <property type="protein sequence ID" value="KAJ3213771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX50"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="288" mass="34496" checksum="183290AED45FFEE3" modified="2024-05-29" version="1">MENLKVIHDLREQSHALLNQLYETQRMIGSNLIYSINQSKKKQHEEELEKNKIKKKKISLKTRSTNTSPIKKTTSKSLEEEELKKKNFDLEKKLLDINNIEKLKKELNLKKIKDNLIFREENFFRELQNFRVLYPDLFFRDDDLDTSSYKPIKKNFPIPTEKNNDQKRISEDENNYYSGFFRVNERLFCEKSTDFLHLFDFDLFNLEEKKKNSFLNFKKDEIDFEDYGVKVSIPTKHLVKLKEKNLKPFTRLTYNPKYSVFIGDHLYKGSESFIPDLDTVSLSVEIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX81</accession>
    <name>A0AAD5TX81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_006785</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000606">
        <property type="protein sequence ID" value="KAJ3214609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX81"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042214388" description="Protein kinase domain-containing protein" evidence="9">
        <location>
            <begin position="19"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="11">
        <location>
            <begin position="534"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="691"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="276"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="425"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1157"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="725"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="323"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="470"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1157"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1174"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1196"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="720"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3214609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1233" mass="140229" checksum="ABA03EFE36526B20" modified="2024-05-29" version="1">MRLLRCLISSLYLISISAKKSTNLILNGDAENGLNFWDWDNSTEIQFSTVGFSLINITDGGTAEAREKMGKFGFQTKLINNEKVLPSTFIVSQLIALPDYVFSGQENGFATFRFSGKFLRYFNNRDYTNLTLNFFNENNEKILFNSQDWLNQQFSDNYENCLEGNIQPFKVGANLGSAFYFSASSNGTVPSNAKNIKISMVFNVLDLPRTNPVMSAIVDNLELIIEYNNIHQITAADKMNSMGLSFYVGVSVGGLGARRNSASTMRRNNLESIYSRSLERIRGRSSRGNQNSSQHSQHPIQQQHRSTHQKPASPLITPVQYRNRPNSPASLNSPSSHISTHHHTPHSGQVVSNYDHRHLHHNHYVNSQQQMHDTRYLNNTNYPSQQTSNLYSRSTVNSPHHARDIVNAPHPHHQPNIVNLPKLHNHHPQYSVSPVLRPLSPHSSSNSMYHSGPTRQILSPTPISHLGLMNETTFPQNTISTASDSSDGTTLDNGNNIRNSQSSGYSSHFKRCVNDTQPRDSLSSSHSLRSKGHEQHEQTVIDFFNSKLNLLKENEKLNHSNLFDNLKSGVLLCRLINLFKPDAIVINYSENPFKQRENISNFLKHSRILFSNLSNETFETEDLFEKKNLNQVINTLLFISKYEIPTSSLKSPALDLKKGFLQEKEKILTYMKSKEKLTLVNEMTDEVLAQYLMGPVIGRGNFGTVYKAIDIKRGNLVAIKRIPLINHNESVVQDLRKEVELLKNLKQKHIIDYYGYNLTANNFDIILEYMENGSLLHLMKNFFSKNFFSESLVLMYVKQILIGLEYLHFKKVVHCDLKAANILTTKTGTIKLTDFGVSKQLSMIDKESLSNVAGTPNWMAPEIIQLEKITTKSDIWSLGAVIIELLTGLPPFGTFNPLTSMFKIVKEDIPLPSAISEELADFLKLCFQKNPNDRPTATQLLNHKWIKKDCENTSLCTLETEELELEESDEELCLSSLNSHASYFGENREFISPYTNRRASCRKRSISQPRNSISSSSTSSLTVQRERYKSFDLPRVSEEAVKIYEGKASFDSAIGTLGRDSTIYVNNDECNSEEEERLLNLYNKFKLKKVPQKKKKDFFFVEAFSKKSADEHNLPKSIKDKEIPLNEVKFNKRAFQKGSSKSNGNNLTKSKRDLFKSTSEPTLHQFSENVNNHGVEERAGDNDTINRGRKNRYSKLWRDEGKKTEPSIEDKHLKSVEKGKKVKNRHSQDCIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXB5</accession>
    <name>A0AAD5TXB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="8">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_008527</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000947">
        <property type="protein sequence ID" value="KAJ3209299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXB5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000005">
        <property type="entry name" value="Phospho-2-dehydro-3-deoxyheptonate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF12">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="9">
        <location>
            <begin position="74"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3209299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="388" mass="42811" checksum="27DDEC0D9EC48117" modified="2024-05-29" version="1">MISGESKEVNGTNLKRKGGPLEIKNKIQFKTTLNETDDKRIKSTKPLIPPQILMEDFPLEDEVSDFILSQRNEAENIVNGIDDRLLVVVGPCSIHNVEQALEYAKNLTSVKLKLQKNLLIVMRVYFEKPRTTVGWKGLINDPFMDGSFQINKGLKLARKLLLDINTMGLPCGVEFLDTLTPQYIGDTITWGAIGARTTESQIHRELSSGLSVPVGFKNGTDGSVQVAIDAIKSASSPHHFLGVTKQGLSAIVETSGNKSCHLILRGSNSGPNYEKKFVTEVIEKLKKNGTEEKKLTLMIDCSHGNSMKKHENQILVVKSVCEQLVDPECKNSIMGVMIESNINEGNQKLGDGKNLKYGVSVTDACINFEETITALELLSDAVEKRRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXM3</accession>
    <name>A0AAD5TXM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Casein kinase II subunit beta</fullName>
            <shortName evidence="4">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CKB2</name>
        <name evidence="7" type="ORF">HK099_006843</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000616">
        <property type="protein sequence ID" value="KAJ3214499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXM3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006359">
        <property type="term" value="P:regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000002">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF39">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01101">
        <property type="entry name" value="CK2_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042148024" description="Casein kinase II subunit beta" evidence="5">
        <location>
            <begin position="20"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="74"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3214499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="329" mass="38163" checksum="74155B4F80B7FFDA" modified="2024-05-29" version="1">MFAIIGGVTALLLLIGTLCCCYHRKKRNNAIIITHIVEKEEEKKKEKKSSFRVLHLKKSDDDFSNSPAANYNDKDPREKLVLKSYIARGYDELSIKKGNTVLVLETFPDGWARVFFKKENISGMFPIGCLENGENEMESNSNYYWSEWFLSLKGNEFFCEVDDEYILDRFNLTGLNTEVENYSLAYDVITDSLENEIEDEKLRMEVEKNREFGKCPRILCNGQNVLPIGVSDQSGLMSVKLYCPHCEDIYIPNSKRHQSTDGAYFGTSFPHLLLQVHNEFLPKKNNQVYSPKIFGFKVHHIANEQRKQDLLKIQNQEKVEKLIETFERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYM7</accession>
    <name>A0AAD5TYM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxidase</fullName>
            <ecNumber evidence="8">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CCP1_2</name>
        <name evidence="10" type="ORF">HK099_005540</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000436">
        <property type="protein sequence ID" value="KAJ3217259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYM7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000009">
        <property type="entry name" value="Ascorbate peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000005">
        <property type="entry name" value="Cytochrome c peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF36">
        <property type="entry name" value="L-ASCORBATE PEROXIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 8 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="9">
        <location>
            <begin position="73"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3217259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="275" mass="30944" checksum="7EE108C55DB7D320" modified="2024-05-29" version="1" fragment="single">MQQTQQIQFQAVSDDIKSILANPDWDDGSLGPVFVRLAWHAAGTYDKTTKTGGTNGATMRFKPESSDGANAGLEHARNFLEPVKAKHDWISYADLWTLAGVVAVEEMSNGQCKVPWEGGRSDKNEKTITVKDIPPNGRLPDAAQGAPHIREVFYRMGFTDREIVALLGAHALGRCHTDRSGYDGPWTFTPTKLSNQFYILLLRIKWEKREWDGPEQYKDPKDKLMMLPSDIALIEDPVMKPIVKEYAEDKELFFKDFAQAFGKLLELGVNRNASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYV1</accession>
    <name>A0AAD5TYV1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000486">
        <property type="protein sequence ID" value="KAJ3216291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYV1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="110" mass="12515" checksum="D591DD032F3659DE" modified="2024-05-29" version="1">MGDPIQITLAIILVVVLICYYWYDRRSRGDEIDVWGGNGNITSNRPRRVSTASNLNHNQYSYPPPTKKHSVHHSNFSSEYNSPETAPYNRNSTTINIPDPPPPTYQPKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ54</accession>
    <name>A0AAD5TZ54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL23</name>
        <name evidence="5" type="ORF">HK099_008142</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000864">
        <property type="protein sequence ID" value="KAJ3210968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ54"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006344">
        <property type="entry name" value="PRK08571.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3210968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="137" mass="14515" checksum="C3079C3F4A0A891E" modified="2024-05-29" version="1">MLRSGAAGNKFRMTLGLPVAAVMNCADNSGAKNLYIMAVKGIKGVLNRLPSAGVGDMVLATVKKGKPDLRKKVMPAVVVRQRKAWRRKDGVFLYFEDNAGVIVNPKGEMKGSAITGPVGKECADLWPKIASSSGTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZA1</accession>
    <name>A0AAD5TZA1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7 9">2.1.1.216</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TRMT1</name>
        <name evidence="11" type="ORF">HK099_000581</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7 9"/>
    <dbReference type="EMBL" id="JADGJW010001137">
        <property type="protein sequence ID" value="KAJ3206244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZA1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160104">
        <property type="term" value="F:tRNA (guanine(26)-N2)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002940">
        <property type="term" value="P:tRNA N2-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.70:FF:000001">
        <property type="entry name" value="tRNA (guanine(26)-N(2))-dimethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000051">
        <property type="entry name" value="tRNA (guanine(26)-N(2))-dimethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="entry name" value="N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00308">
        <property type="entry name" value="TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF3">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="414"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3206244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="439" mass="48724" checksum="DC1ED9770C9A9C4E" modified="2024-05-29" version="1">MTTTTNPTIKEGMAEILNANGEVFYNPGLRSIRYGKEIENNDQNLVIFANDFDKDAVENIKANIKLNNLEHIIEPSLGDCNFIMYKAMNENLKYDVVDLDPYGSASPFIDAAVQSVNDGGLLCVTCTDMQVLAGGQTEANFTKYGGINLTTTPYCHEMGLRSLLHCIQTSASRYKKYITPLLSCSIDFYLRVFVKISLGAAETKKAVCKTSMIYHCHSCKSFTTSSLGKRIDTGKGFKYTTNKLPVDSKCIECGSSITVAGPLYSGPLHDVTFVKKMIDHVKNNPKKFGTEVRMTGMLTLISEELEDPFYYAIDKLCQVVHCSTPALKLVTSALLNQGYKFSASHCLSGSLKTNAPSTVLWDVIRSHSKLTKSREAKEGEIVMKNILSKDVKVQADFSIHKDCESQSRKFKLVRYQENPTPNWGPGSRAKGKKRKAEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZQ6</accession>
    <name>A0AAD5TZQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005077</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000381">
        <property type="protein sequence ID" value="KAJ3218424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZQ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000032">
        <property type="entry name" value="Krueppel-like factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="239"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3218424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="299" mass="34424" checksum="BCB986B3650C09CE" modified="2024-05-29" version="1">MEVINQQDFNISDCFSSESYSSLSNNSYSNQSNQPYLKDSFQNDSSYSNDFYPVPDLLPHNPSHSPSSQDESYSTSYIDTANYPQQQILESPYLPYQDLHFNQRDFSNSPLNSPLMLPRINQLYSTEYQSPNSTPINYNQLQPIDYSSYDQEQLQSYTGLQIPSQFTKDDLSNFHHSPVSHQALQVKKPKVQKKSKQSSPFADDNLEILSCPHENCEKTFTKQFNLKSHLRSHTTEKCFTCDLCAASFRRSHDLKRHIRSLHVAVKAFACPTCNKRFARTDALKRHCSRPQTLCNKSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U084</accession>
    <name>A0AAD5U084_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000352">
        <property type="protein sequence ID" value="KAJ3219109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U084"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018810">
        <property type="entry name" value="UPF0662"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086:SF1">
        <property type="entry name" value="CU(2+) SUPPRESSING AND BLEOMYCIN SENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086">
        <property type="entry name" value="UPF0662 PROTEIN YPL260W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10303">
        <property type="entry name" value="DUF2408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="712" mass="81482" checksum="BB782542A50624EF" modified="2024-05-29" version="1">MENFLSFSTIAASNQQPSQPQKQQINLDGLDEFPALVLERKLNSLLKELNLRLLEIRKSSLKDQRLEKLLIVNLKNEWKNLKKLIKKFLKVTTNQSNKSSQENLSSHIKVENLETYEKEREIEIEKFELNLQDSIHLFLFNLCKLKKFPMELHAQYSNIQKTSKILKSYETDGFFTEASLDALQKDLFLIKDIEVEHHEDHFLNELISICRDSKVLADNLILRLKASLRLISPSLKEIYNRLVEIKQSLGQLKKNNNTTHSSPFLLSEIQIFQDELLEIDSVRIDGSFVDNNNVIVAGQGAVIDLLEKCYDDVHELLAIRGDDGENDQDNPLRVYYETLEDLKFRLEKLVLTDKWWSQPGGESSLEKKLVPIQIKLGEIDSKRIDGKFLDEKGGVPSGQAILHFLIHKLKNKKNDMEKYEKKSWIRSLQTGNRLMQKIMLENVTDSTELNGYECSIVNTIRNVLTDTIEIDSLSYDVHNTKKYFQAYYKSGILYQEYNLKQFNVFPLSTSTIPKDNRFDTLLLCKAILGLCGQITNGNVSVENYMEKIGSSLFNLKNKLFKPRNGMEFSGSVKKRKKPGDDDENEDDKKTVKTITKTKAKPKETISVKSMKPNETIEKTFVITISPTDKTTKLSSTTSSSSNTIKNLTTGNIMNKVSVKTVTVASTTVTVETTYYEATTTITIYADRKNFPTDAIFHGTRKVNVASIKFKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0A6</accession>
    <name>A0AAD5U0A6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Plectin/eS10 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000309">
        <property type="protein sequence ID" value="KAJ3220299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0A6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="80"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="325"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="417"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="457"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="86"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="348"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="502" mass="56215" checksum="32B9B8CFED210566" modified="2024-05-29" version="1">MKGVLVAKKDYNASKHQDIDVPNLQVIKALQSLNSRSLVKTNFSWQYYYYYLTNDGIEYLRTFLALPAEIVPRTFIKTQKSVGRPGRSDGDRPQRQQRDGGDRDYRRRDAGEKKEGAAGDFKPEFVNEEEDYLDLDLICDSDSELEEEWFTSPVSNKILKSEKRLSLTQFNSLVKKSLLIEREAKLILKDDVTEKTKKNEGDLTKNTQFERDIVSKNYLNNDFSLSFGRHRKSDLRSSLSSNATFRNDVINKDVEKYNLSIATKSKKTDIPELVSPTSSMFSSASTDLSVSTKCSSNTSVSQSRSGILKSVPQYSMHTTASFRVTPTIKLRQPSPSRLPEPKSINVETPSSRRSFSPTPFNSRIPSPSPQEPFSKKEMSFTKAGTSFPTESRSFKAGSLKRASMLPVQRVISPIPTLTSGREYSSSRSKSPSATTISSSSFSLGKKNNFSSTEYNAKISSSVSSIPRPSSPSLIPIPSASRKPKPRPHSYIPVFSYLSKKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0V8</accession>
    <name>A0AAD5U0V8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000378">
        <property type="protein sequence ID" value="KAJ3218479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0V8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF105">
        <property type="entry name" value="CARD- AND ANK-DOMAIN CONTAINING INFLAMMASOME ADAPTER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="415"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="623"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="753"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="491"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3218479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="792" mass="86789" checksum="4140C2D0D556043E" modified="2024-05-29" version="1" fragment="single">DQDPSVKIIPILKNSITLKEKNSKTSIDKEMSTEIKIENSTQINKNIENNTAVKTENNLESTETNSLHKNRSRSTSSPSPVNSSTILQTPASPTVQISRRGPPPSRLDTSNAVTGGKIPGVLVASAQSANAISNSKSNNSNIPNTQIEPGRNSFAFKSITKTQSFYNPSTSKFDSSPSTARSSLGVSSPENSPKSISGSFSSSSFKQNFGFTASSLPSPGYLSLAEFKQRDTKPRWQRFILYQLYTTDMIRSKVGVTNRVRKDSGKKEKGQSTLSKLNALLKPKKKKKSVAVTFHLLNLAIHDNRTSAACTLLEDLTPNSLKKKRPNETNNCFLHAVANGLESVCLVLLEKGFPINVNAPAVSTTISQPMINQKKSNNNTEPFAFPSYFMTVVGIGLDNVVRSMVKKANVNQTWYGLSPLHLACCKGNPGVIRSLLENGADHNFGLPFETYTLLCKIKSDAAKAATSLISSSSYKRQFGSKTITAHKKGVKNSDKSLNKDDGTTISPPLTSTSMPHSHLPETFFKNKKIFPVELACAGKHVDACKLLLLKYDTKTIQHLTYPYFAQQSLEISCIFLKNGLNPESTFDPWGSNAVQVAARNGNLGFLIAFFHCFKIDINKRGENNWTFLHEAISQKHKAVAQFLIRNGADITCLNNDSETAHSVGLRVGISENELKEYFAKSTVSIEETQIMELIQKYLLPDPVFQKATSSPEQKNLQKTRWRALEKEKSNGSFAEYNGSEELLPVSTNSNNSSLLDSSISTNTNSATSSPSQKVSSKLSGEAASFFKVFKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U134</accession>
    <name>A0AAD5U134_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007577</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000747">
        <property type="protein sequence ID" value="KAJ3213091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U134"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="185" mass="20308" checksum="FF77D7141F24D124" modified="2024-05-29" version="1">MYCHISCVAAIARLYSVAYPACNLKSIAESDSLDFYKSTILFKEGLCTSEQCGKAADGVLETALKSCSEEDKAVNFNITLTDETESIPISDILSLIVPSNEYKKSPLCTIKTNTSDLSCRGDFLLNSLDCSTEDPKCNKTLLKTQCEVDGCMHKVITETSASSKPFEKEVSVGYKMACDRYLKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U162</accession>
    <name>A0AAD5U162_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000256">
        <property type="protein sequence ID" value="KAJ3221039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U162"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF3">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16010">
        <property type="entry name" value="CDH-cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041987117" description="DOMON domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="4">
        <location>
            <begin position="27"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="755" mass="85189" checksum="A84223FDEAB7B6A6" modified="2024-05-29" version="1">MKVLYLCIFFLQLTTQVFSTCSSSQQGQVCIEGKLASDNVQYTIHSSYAGYVGIGIGGSGEMSGCDMYVAWKRSDNTVTLSKRAATGHSLPLSVDVDFQILALDETISFPELLNSQNLLKITFSRPIASSVVTIGTETNYMWAASSTLPDDVDNPASSFGMHTEFGNFAAVNLKALSPLPPAITISTTSTTATSIRKSETSEIASATKSISSVTSATQTSSPVNSKLEENSTFFTNVPISTIHAIHGILFFIAFVITPFLVIFLSNFMLDNKNNWLQKFAPLLVFIVFTGLTSIAGLLIELLSLNGPHFGKDMYGHKIMGLLSFVLILLFTIGCILVKNLFLSNLKKKIFNYIGASVLVFGILNCYMGLKLLKITNSPKEIEFTEKDNNKKILNDFQLNYIFLEILFFCLIFIFSIILILQTIFLKKLEKQKSTEVVNNNLNYLDEKLEEGNSKGNDLVIKPKNRESIDNMESFSFFDTFNSNRKETSQNDVSDESSYFSRDRLEPGYSHKNSMNKSYKERQTELSGEEMRKSADLRSLTSNNKKSLDRSISFNSTFDNKNNSENNSMQSRVVQRNLTSSTTSFPARNASDELRRSKTAINKSNRMEELLLRQKSMNERKTDEHSDFMLYMEKRFQENRLKQQELTKSHISKEKIERPMRHLSTNDASIKQRSSLHNLKNNDLQDSRESILSRGSSEFDLNSFVSSSSYVPKRLPQNLRYDVTPLNSVNQASAKTRNVESHTKNAHLTQKKRYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U173</accession>
    <name>A0AAD5U173_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Holo-[acyl-carrier-protein] synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000408">
        <property type="protein sequence ID" value="KAJ3217834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U173"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="13010" checksum="19056BCAE1E26E6B" modified="2024-05-29" version="1">MILGIGNDLVLLSRFKLVADRVTIRRLAKRILTEHEQEVLFSVNSAYKALFGHYKLSWKDVEIRKVNGKPDLFLSDNVRKLFDYEIKGFLSISHDGEYLLANVLFEKTREPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U177</accession>
    <name>A0AAD5U177_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000275">
        <property type="protein sequence ID" value="KAJ3220767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U177"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="28268" checksum="8B8029BED01ECFBC" modified="2024-05-29" version="1">MGCGASKDSVAVEPTTSAQPTMTEKKASQADNLNVQQQEAPQQAAQEQQQATEEQAAPAERNSTKDAPAKNLEELRKSQASKKSQHSLKQAANQPSNQQLNKQASQQKSLAKQLSEQQQEQQQEAQQEQQQDQQLEQQQEQQQEQQQDQQQDQQQDQQEQEQEQQQEQQQNEETQEQQHEQQQEQAEQHNEEAQQQHEEQQLEHEQQQEEAHGAENDQSENQAAEQEQSHDAENHDEQQNQDEAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U195</accession>
    <name>A0AAD5U195_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000259">
        <property type="protein sequence ID" value="KAJ3220979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U195"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="118"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="208" mass="24293" checksum="E2FDF0002733F088" modified="2024-05-29" version="1">MDPYQKEIFRENKNEVSSSVKKKGTFRKDDKEKYTNLEHDNNYSKKIGGEKKVDVIEKEVPNYEVSGKLAAELNTYKGVELKYSEPAEARIPKKKFRLYIFKDNEQIDLLHVYRQSAYLIGRDRLVCDIPIDHPSCSKQHAVLQYRQVEREGQKVIKPYIIDLGSSNGTVVNKEKIPNERYVELLFGDVIKFGFSSREYVFMNEEVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1B3</accession>
    <name>A0AAD5U1B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000538">
        <property type="protein sequence ID" value="KAJ3215502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1B3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="497" mass="56959" checksum="120D362C6DBE7654" modified="2024-05-29" version="1">MPKSKVCHCFWENCDAVYNSEEDTYLHALQTHSTKGNQECLWISSEIKGLSIRVSLRVSHFSLDFRPLSCPLCQKKIRSRQELGRHKKTHLSSDFNEGMEEIGNHLFDAESPPLDDVAAHYFDVKDADSYLRRQQADSFISSSINAEINSNKTMLIPKSNKVNFYTLDSFIDDNECEDDDVKEFCEVLDVDASPEVNKEIRLLAEVDEDALSLPLVSIDKKKIVLHKYQIEILKRDSKFPLSINPPSSFLVGITCGLFWGMCVELTRDFSIDIPEEIKTTVLRVAEREGILAPQFQIELQYYLVNKNNIPLSKLIEHRRQSVNTNFGRLILSIVKVLTFELNSEMEKMNLVITETASNEDEFEWFEPIEGSPLFKSPSDCSAAAILLKYTITYHTDSINLSLRKAATKRLGECLKMEIQKLVKTIIFGNNKNCRKLCCFGLLCNQGDTLFNENFFDFGKSEIFIWLRLGSDLNYVINNDIEFDDFKDLVGVKLLKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1I3</accession>
    <name>A0AAD5U1I3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Maintenance of mitochondrial morphology protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">MMM1</name>
        <name evidence="11" type="ORF">HK099_005084</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MMM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000382">
        <property type="protein sequence ID" value="KAJ3218394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1I3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21671">
        <property type="entry name" value="SMP_Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03103">
        <property type="entry name" value="Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027537">
        <property type="entry name" value="Mmm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019411">
        <property type="entry name" value="MMM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF0">
        <property type="entry name" value="SMP-LTD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10296">
        <property type="entry name" value="MMM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="36"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="10">
        <location>
            <begin position="78"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3218394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="309" mass="35622" checksum="96F7568B33DAA937" modified="2024-05-29" version="1">MSDLWSTSKEFIKGFIAGQIILICFMFFLIKFFLFQNPSKNVSTKRRRKIFEVTKTHSPQNQALNILSKIRYDPNSTGAETCEWLNVLIAQAIAKYRNDSGFLNRIIRVLDEEINGSKKPNFLSPITITEFSLGEDFPMLKSSCIRFVENSINLRAEIRFEFHDQITLGIETQVLVNWPKIMMAALPVALSVTLTKFSGTISIEFINSKDSPASFISISILEEDLNLEFDCKSMLGNRTKVKDLPKLTQLIINRLRKSFFELIVFPNSKKFNVPSFWPDAEENFLELNLEQEDELENLIDENLENKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U242</accession>
    <name>A0AAD5U242_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000335">
        <property type="protein sequence ID" value="KAJ3219572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U242"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="773" mass="87228" checksum="5DDF801402E0D9F2" modified="2024-05-29" version="1">MAETSCTSSDVRNCSSLTSDVVAIDRATYSALNLSITTPVPSCSPGSEGDERLFWQVETATNYNTALLKTNLALNILRDFWENTKANSLQTVGVDFINFYRFICSEILSYNDSDCESNSVVHNLPLDPINDEEVKELAEELVKDENVMNSFLADVRDWDAFRLLMKRHSAALCVVPIEDENVLEKHSSSQIRANTESDYELVVPVIPEAENAPFNNNMKLKEKKNLQSDVKNKRLLRVLNNSNAESTLQSKLIALEKVNLEKEKQWMQEKMELIKQFEISKTTLTFTTTSSKHSDLKSIASNQVQVKSILKKPSSDLNTILIKKNIQWDNAVLTAEAEKERSRLESAILGFYRNSGLNNASKIAFTADNSVNYEDDVGDVSGLEMLRSRHTEPRLKKIAIPGVSSSKEDRSREESKQREIGHRRNIEGLSRKASSLPEEFFKISNEVFYQTKELDVKPKIGLIKVTDESAVVNVLSTDKEKNDDNIYNSLTSEKHRNDSEGKEELVRNEDINSNKEFFEIGSSDTNHSCLPNLCGESETVVKNTEEGMLTIEANHIKEIEVSVKLESVASDIKDTINTDLDEFNNSICVTQLTKSSVNTENDIDNLLGQSQFNDFIDDSDITSSEMLKIPLQEKVEKLKMQKKWKENFLKFIKRNNKSESFSTDTSVQIAKNDFRTLSSSNTLLTDAGIDESELFSNASTLNRTDTCEDYLKRTDTCEEIPKKAKKRFSAFSLSNFDFSNISIGTSKGEVSSPNLQSRKKNKNAKKQFGFALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2J4</accession>
    <name>A0AAD5U2J4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleoporin Nup54 alpha-helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005387</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000416">
        <property type="protein sequence ID" value="KAJ3217642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2J4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006607">
        <property type="term" value="P:NLS-bearing protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.490">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024864">
        <property type="entry name" value="Nup54/Nup57/Nup44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025712">
        <property type="entry name" value="Nup54_alpha-helical_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13000:SF0">
        <property type="entry name" value="NUCLEOPORIN P54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13874">
        <property type="entry name" value="Nup54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup54 alpha-helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3217642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="532" mass="56950" checksum="B2A9AB527E79D19E" modified="2024-05-29" version="1">MLGFGGFSQPAATSQASGDIAIPFLNSKFLEKLGFAGFGQPASTQPASGFGQSAAKPATGFGGFGQNTISGFGVSNQTNTTTAPTGFGAFGKPATTGFGGFGQSAAAPSSTGTDKIYNILIFLGFGGFGQPATTTAPSGFGGFGQPATTASSTGFGGFGQPATTTAASGFGGFGQPATTAASTGFGGFGQSATATGSTGFGGFGQPTTTSTSTGFGGFGQPGTGFGGFGQPVAKSTNTFGNFGQSNTGSNNLFGQPAASTSLFGQQQTNQQQQPVLYANQGTLQAWDSLMQIKQYWDVESSNCQFRHYFYNLVNPNDVNAYQKPPNEDEGLWQQAVRDNPDSTCMVPVLAKGFKDLKFRMEQQEHQKELFKSKLEEASAIIEQIRSKHLLETTINLEEYKRRHLEMAHRTLQLMTKIQVLRSKGYSIRAEEEALKIRLEHILQQLKKPNQFRGRVQELWAKVQQLKEAKKFNNNIGASGKIEYSVIDQDALKWIFQAISDTQSGLKHLTEVVNVDKEDLEMIANGYRNFYNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2X2</accession>
    <name>A0AAD5U2X2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006089</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000502">
        <property type="protein sequence ID" value="KAJ3216050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2X2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043124">
        <property type="term" value="P:negative regulation of canonical NF-kappaB signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038753">
        <property type="entry name" value="NFKBIL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263">
        <property type="entry name" value="I-KAPPA-B-LIKE PROTEIN IKBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15263:SF1">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="254" mass="30805" checksum="80B86244320AB5AC" modified="2024-05-29" version="1">MGKKQKKKERKAFRKYYKNYTPPTLDTTSSAEEQEKEFLDESEERRRFNEKLFDNLMFDEQELFGRYSESEYVESSYKEPILESFEDWTENIRREKLRKTQQEKNSATYLKKKKFDLKQKELQQFEAEERLKEELRLKKLYRKLKVEYNLGWSTIKNFTCGSKPLLKLTDLPVPSFKKLLLNKSCFEEFIFFELSEDEDNIQLKKKKLVLQEIKEFHSDKFFKFKNSFNSNDWDSVVNTINDICSILNEILNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Z0</accession>
    <name>A0AAD5U2Z0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">General negative regulator of transcription subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_003913</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000264">
        <property type="protein sequence ID" value="KAJ3220906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000012">
        <property type="entry name" value="Ccr4-Not transcription complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055454">
        <property type="entry name" value="CNOT1-like_NOT1_connector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25097">
        <property type="entry name" value="ARM_Cnot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="13">
        <location>
            <begin position="226"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="12">
        <location>
            <begin position="395"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="11">
        <location>
            <begin position="635"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="10">
        <location>
            <begin position="923"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1-like NOT1 connector" evidence="14">
        <location>
            <begin position="1146"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="9">
        <location>
            <begin position="1497"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="389"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="874"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="874"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3220906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1868" mass="213236" checksum="A0E602C071BBC146" modified="2024-05-29" version="1">MSQQITLSSVLNDVGYAGTASESNLNIVIDMLSQKPTEHDIGKTLVMFSNTQTSLSPTSPVFPQTPPQLSWNIPLFIKTILTKYSKSNMVLEWPRLIKSSLDSKDFEIKQLQFIFNTYKLGNKAKWDHQNKKSQFLYSLLQNYSELIILNKTLVTKIFVNENTQQNSLTQSWQNNAFNSLDFFLQVLNFSQFDQDLKKLFDHFQINFPELICIGLSMLKTQTQYSQEIFQKLFITFITGHPNSNFVLQRVWMNSQPLLIESLIQIYKKDKSTLSRILDISQDLKALSKILDVKPYYFTIDLASLASRRDYLNLEKWLLDKTKEDGDNFIKVCLEFLYEKVMVDFGGAGGVGLSNDVVTIFIRILQNQSNYMSPENSAVLNEIITATSHSYQRNNPEEEAVPTPTTSTSAHPSFSPDVEEEATTYFFRIYKGEIRIPQMIELLLLYKSSQNRREQDLCNCIIQSLFDEYKFFPGYPEKHLLLTSLLFGSLIQHQICSGNALGNALRYILDACRQPPSSPLFSFGVQSLRQFQSRLLEWPQYCSLLLQIPHLESQCPDIVAFIKKHGGQQNITIDDQMKLPESRNSQQQYGLSVQENSNNTSNIMGLNDDDEDSEAYPAFSALKVDIIEHEENMFYPPAEAQQDKILFIINNISPTNVDQKITEMKDIFINEYSKWLSAYIVSKRVSIEPNFHLLYVQFLSGLSSPILDKLLLLETYSSIKVLLNSKKTVISSEERTLLKNLGMWLGILTVARNKPIKQKNLSFKDLLLEGYDNSRLIVVIPFVCKVLEQCMNSIVFKPPNPWLMATMKLLSELYHFADLKLNLKFEIEVLCKSAKLDVKDITPTNFLKSRPKHRQEESQLAKNFERLAIAPSTVSAPPSALSSTSTTFNTTQGGSSGEDVSIGYPNLVNFLTFNASLPIFQAQPSLKRIVHFAIDRAIREIINPVVERSVTIAGIATRELVVKDFALEPDENKMRKAAHLMVQSLSGSLASVTSREPLRMSMTQHLRTLFSQNGISEQAIPEQAIFILVADNLELACSVVEKSASEKAIAEIDEGLAHNFLNRRKHRERTGQPYYDFAIYSSSRYPSTLPESLRLKPNGLALQQLRVYEDFARLPRIVAQEQTFAEENVPLQTAQAVDKFTQFLIELEKVFPQMDIGSVTALPPQHDIHTILVHAPSIVNQSCNKDEVALILSQRVLNLLFKHESQLPLETYVLLLERVCETSKKVAKEVFQWLLFNDDDRKYNVATFVTILQARLLSVPELDMQLARLIDAGRMSVTEFAQKLARRCILEEPVLATQNDFFNCIDMFTKLVQRGKASDSVVEFMDALKKLNTFNPLKEYIGKDIDNPNLREQLIILFNDWVGLYHHPSSTEKVQVAHVNHLISQGILSSEDISSLFFRVCVEQSVEIYIKNKAAQGVPHVFAFQAVDAFARLIILLVKQFNDPHANGQNINLNISKINLATKILSIILLVLVHNHEQQRNNFNQRPLFRLFSTLLNDLHYFETSLQHIYFQILTAISNTFHTLQPSFLPGYTFSWLQLISHRHFLPKLLNAENQKGWAFYQRLMIDLFKYMAPFVKKKELSEPVRLLYRGTLRVLLILLHDFPEFLCCYHFSFMDVIPHQCVQLRNVILSAYPVLMNLPDPFSTNLSVTSLAPENHIAPQILSDYTSSLVTSNLKGELDIFLKNRAPMSFLTNLKNRLIMPHQDGSGGKYVVHLINSLVLYVGIHAINISQSKNTANSLSGFSPSAPNDIFQQLVNDLDSEGRYFVLSAIANQLRFPNSHTNFFCGLMLSIFADAKQEIIQEQVTRVLLERLIVNRPHPHGLLITFIELIRNPRFNFWEHTKFFRCAPEIEKLYTSVAKSIGLIISPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U318</accession>
    <name>A0AAD5U318_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PAP1_2</name>
        <name evidence="16" type="ORF">HK099_002015</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000163">
        <property type="protein sequence ID" value="KAJ3222705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U318"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000002">
        <property type="entry name" value="Poly(A) polymerase alpha, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="15">
        <location>
            <begin position="7"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="14">
        <location>
            <begin position="220"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3222705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="286" mass="32121" checksum="5B8502F379E8D393" modified="2024-05-29" version="1">MQKTQLGVTAPLSTAPPTQKDLENTKLLIDTLVSMHQYESDDEAELREQVLGKLHDLLKNFVYVISKKRNLPEQVASEAGGKIFTFGSYRLGVHQKGADLDTLCVVPKHVTREDFFTDMFEALKSRPEVTEITAVVDAYVPVITMKFSGIPIDLLFARLSVPTVTDDLDLADPNLLKNLDEKCIRSLNGSTNAKITPIFLFFIGSRVTDEILRLVPCIDSFRTALRCIKLWAKKRAVYSNIMGFFGGVAWAMVVARVAQLYPNASAGTIVAKFFRIMKQWYQIIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U380</accession>
    <name>A0AAD5U380_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Profilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005776</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the profilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000466">
        <property type="protein sequence ID" value="KAJ3216668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U380"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00148">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047182">
        <property type="entry name" value="MRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048278">
        <property type="entry name" value="PFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005455">
        <property type="entry name" value="PFN_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036140">
        <property type="entry name" value="PFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041178">
        <property type="entry name" value="RPA43_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103:SF1">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00235">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17875">
        <property type="entry name" value="RPA43_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00392">
        <property type="entry name" value="PROFILIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01640">
        <property type="entry name" value="PROFILINPLNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00392">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55770">
        <property type="entry name" value="Profilin (actin-binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="9">
        <location>
            <begin position="91"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="RPA43 OB" evidence="10">
        <location>
            <begin position="160"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="8">
        <location>
            <begin position="433"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3216668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="565" mass="63221" checksum="BA3CD93A378C4AFA" modified="2024-05-29" version="1">MKEYKKKNSIINEEKLEISELKSSHKHKKIKLEKTKRLNVTDTLEVNNSKINKKNFNTEKNDIEIINLKIKPEVKNKKIKANFTTINSTLFLTIPPIYSLNIKDGITNFLDKLLNRYVDKVKGVLVSYSNLKLLQNAAKIINESPFLNFKIQLDLFVFNPNIGDVLVGIVNKVSQDHVGVLVHGVFNASIPKSNLNDAYFTLENNSWKFEKIHTIKPGKILKAAIHGHDGNVWATTKGFSVSTTEMKTLADAFLDASGIRAGGIHLAGVKYFALTCNDRSIYGKKGAGGVICVKTKQAILIGVYDEPVQPESPDERVKRKINTFNKENYELMNKKREQLKIMAKKAGLPLKFTSFQNLSLLSANRPHQGVILECGPLKLERIKYLSISDNEDTKILKYQVNYTENEFKDFNYNGEYRKKFPIFLALDQVIDPQGVILTESESAPLSSAVSKASSGALEAMSNLYVVNNLVKFLQLSKSEGFEVVGTDIGSKNNVYDLSEKKKDFNRPLILVMGNEGTGLRSIVSKVCDSHIVIGLDKDRINHVEEVVESLNVSVAAGIILNQLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3S4</accession>
    <name>A0AAD5U3S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNH nuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000203">
        <property type="protein sequence ID" value="KAJ3221884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3S4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13391">
        <property type="entry name" value="HNH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH nuclease" evidence="1">
        <location>
            <begin position="142"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="320" mass="37512" checksum="2B8380A460BA3F4B" modified="2024-05-29" version="1" fragment="single">MIWNLIVATKLNKTKLELLVEKDETFLYLDKERRELAEWLNELDKQRGKLYDSINLLYYWKNLFYDRRNLLLKEPVEYKRIEEIKALAFESGSSISKRSFESVGKTGCIYPSKQSSQSSHSSRSSKTQEEFRKSVLARDKVCIISESVEAANCEACHNVALKDKEHFDDYCKLFEISFHPFLDSDSTKRLNSVCNGILFSPSMHRLYDSHYFTILYSDGKYEFWCQNQDLLDKVMEENPGVKLLTEKNGKEVNFGDDDTKKPYKNFLKFHNLQFINKASGLKGNADPTEFKRNDSEKTLKLYSDKEDFCDDMENVSFYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3X1</accession>
    <name>A0AAD5U3X1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Stress-responsive transcription factor hsf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HSF1_1</name>
        <name evidence="6" type="ORF">HK099_000944</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3X1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF206">
        <property type="entry name" value="HSF-TYPE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="474" mass="53406" checksum="9F4BD160FD49A35F" modified="2024-05-29" version="1">MKNLKFIEKLYSILDSDLHCNCIKWSDTGHSFIITNPEIFQNEVLPLYFSHANLKSFNRQINYHSFQKLSKTKSNYNLIKEDITKEEKEVLKPKEFFNVNFIKGKPELLKNIVRKNSNSSNNLYNKPKKALMSETSLTSSNNTNISTTKPGSYSVSHLSSISDETKNTLHSQPLPASTLPGTFYYPFGSSSTTASESTFTNSTSNTALLITELQTTSNIHLRSQSPNFNSTLSPTKFTSESASLSDTISEHTLINTSNNFLNQQSFTSLNNITQQRQFYSPSSHDLRSFTTKRQSSSDISSFSYSKPAYIRHHRQSSDGMDYSQMYSTFYTRNRQSSADANFSHKPMFNSTNKATSSGDFEFASEESDLFNIINETESSVDLDFSGLNTGISNNQETVSNFEEITSPVVPLEMNLEDFLDSTDQVTTALNNDLTTFHENPSITEFNNNLSNTLVITEGDENSGITQVNNFDFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4B8</accession>
    <name>A0AAD5U4B8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">RhoGAP-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_000619</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000115">
        <property type="protein sequence ID" value="KAJ3223848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4B8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="F-BAR" evidence="10">
        <location>
            <begin position="398"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="9">
        <location>
            <begin position="787"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="248"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="745"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="965" mass="109452" checksum="779B771AB2225ABB" modified="2024-05-29" version="1">MEKESDLENSEVAPEYTPQATQPVVQEAAEKNGESLTDVNNTTQDNEILKNAFPLSETSIALSWLIAIIITLIESAFGIFILSILLLQKRSDRVFDIVLRKNCPQLYINNENSFGQDNLILGKEFKNSFTEIFCFLLTLPINLLPVIGQGLFIIANGYIQGPRVHTRYFVKKKWSQEEIAKHLSKYRSDYTRFGCAKVLFESVPILNMISEYIFASAAAMWASELENSAVRLNSERKNSNTLENLTFAPNQLLSPTRTSSAGQIDPSKLSPRTSSKENISPPVSATSSLEIIEEELLNIINENKVDYTPTLHLKEKMDNEIKNPQTQNSEVSGEISDLLTEYNMGQLFDMNSGLPISPASNKSIRLPDPLPPASVTSSQNLNVEKVIEFKNHVNDTNEEESDLLHQLCDYENGVDLLAERIKQSLHSSKESVTFLKKRALIEEEYSKQMAKLVASTNASNQSGRDGTYSEQFDHFLKIHGKIADSRMKLSQTISGIAEDLNTIQKNGEKSRKQLKEAAVKYQKSVNDSEISLEKIKLKYELSSEEWEKFVLLKENHSFSGEVSSANANNFKLPKSVSGMNLFKQSAGKGSNSLLKLQRNEEEARLKAANANENYKMQLAKTNSIRTDFFKKQLPQFVTSLKDTCDEVDNGLQTFLLKYAHEMEASMMKEALAISPLERDDDIISDKSSEPGLISCLTKIENQLDFKNFNMLNLDHNRTQNKPQYKKENFQYKEFKLSDSTLQLQQQNQQLSQQIQEKQHQHKESSSLNSMQSRNAKTSYQKNLYFGVDLTEQLIRDNKEIPTVLEKCVQLIEDEKYGGLRSSGIYRLSGTNGEVNLSEQSEDIHDFTGLLKLYFRELPDPLFTIELYSKFIEASKHEDSRYRLISIHELVNLLPDAHYATLRFLMGHLWKVQQQEEVNKMNIQNLSIVFGPTLMDLPDSGGQGDFSAMARVVEIVLSNYSVIFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4J2</accession>
    <name>A0AAD5U4J2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Alpha-1,3-mannosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_008711</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000099">
        <property type="protein sequence ID" value="KAJ3224255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4J2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000033">
        <property type="term" value="F:alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392:SF1">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3224255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="29875" checksum="D1EFB7EBF7067918" modified="2024-05-29" version="1" fragment="single">MIRARQKLLKTLIFISILTSFAIFLYLNQNFGNSQIISSKTDVNQLSQLEKDLLVMALAKYDNNVVDFQLLGQQLRLLKKLYNNKFKSKLELENYLMLEKKLFNWFLPPTKNLEELKNSFKGKGIVMCVGEGKNGYLHIAYSTIDIIRRIFKSNIEIEIFYLGEKDLKLENRQIFEKNFKNLRFVNLEEKVDNKFLELKGFELKPFAMLFSSFERVLLMDSDTIFLQNPEKLFQFKSFLYTGSLFFHDRTYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4V5</accession>
    <name>A0AAD5U4V5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4V5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="345" mass="39237" checksum="9567B17D0CAA4486" modified="2024-05-29" version="1">MLKSSRPQTASKVNGFNSRPNSALSQLLSSAGTEESHPSFSFRRMQIHQKHFNSNASTHSNFSEISVQYVKSATKMKLDTEDLVSKMYGSQVKRLDASNSSPLTGSSNSNTESAIRKQYSRKSINKKMDTKKTFTKKLHISDVSSKVDLKLGLVESEQFDNATEDYQSECDLKSTITTEKLFLNSRNIDGDLRYEIPPAVLKGTDIQDYVSFNMVRSPEERSLNPDKLNLNSKALTWLTPLSKKCLQLYGEEYLSLLNYQNNSIKKIQYLENLRNLVFLDFFNNDIDKIVGLGSLGELKVLMLGKNKIKKIENLDSNTKLEVLDLHGNEIIEICMNFYVHVFEFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4V7</accession>
    <name>A0AAD5U4V7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylosuccinate lyase</fullName>
            <ecNumber evidence="6">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_004621</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000331">
        <property type="protein sequence ID" value="KAJ3219656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4V7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03302">
        <property type="entry name" value="Adenylsuccinate_lyase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.60:FF:000001">
        <property type="entry name" value="Adenylosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000005">
        <property type="entry name" value="Adenylosuccinate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43172:SF1">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="590"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Adenylosuccinate lyase C-terminal" evidence="13">
        <location>
            <begin position="354"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3219656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="670" mass="75886" checksum="E725BAEB957C7E83" modified="2024-05-29" version="1">MATPTQNRYQSPLTSRYASPEMAYNFSDQNKFSTWRKLWLVLAKSQKELGLKDITDEALKEMEQNLTQIDFVLAAEEEKRRRHDVMAHVHTFGVACPSAAAIIHLGATSCYVTDNSELIMMRDALDMIIPKLASCIEKLAKFSEKYKDLPTLGFTHFQPAQLTTVGKRATLWLQDLLMDLRNISRTRKDLYFRGVKGTTGTQASFLTLFNGDHDKVEKLDELVTEKVGFPEAYQVKDKLKIDLDVLSTLSSFGASAHKIASDIRLLAHLKELEEPFEKDQIGKKVLRSNLASSNVQHTAAVQWMERTLDDSANRRITIPEAFLTADIVLSLLQNIFDGMVVYPSVIHRRILQELPFMATENIIMEIVKQGGDRQQCHEEIRVLSHQAARMVKEEGKENDLIERIKKTEYFKGIWGKLDELLDPKTFIGRAPQQVEKFLKTKVSVALGPYSKQLETGVKQILLILKHLAVCDTPPAWSCYDFCFKNVTIEFNGDSAILIPHIVSGTPCDRKEFCQIQAFSLDKNSNGYTRRYLNSTTHGVSQKIELQNNLLISVNEYDASETFPAGECYSALKPVVLAATPLENAKSDSKIGLHIGIAIPIVLLLVAAFVIFYFWYKKRKNAENEVVKNDEETVKVEPLAPFLMHPRYVAIADYQPILDDELYVKLNNSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U541</accession>
    <name>A0AAD5U541_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U541"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="21749" checksum="BD3CC4A729CB4F30" modified="2024-05-29" version="1">MLNFVKKRALHNHWHFHYNNGTNDGNSTGEVNVKKKNISTNVVTVKETNSGFTIPVLKGLPLTTSLFHTIPIHESSIPLTTSNFPTIPVHESSIPLTTTMFQTMNAPTSKASNLPSNPSALIQDLPNSVSITIYSGIAILILATLTFVSFCFLKKIRIVLISKKKEEEYFDDVFVNNSIVAYTERIRETRSLNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5J7</accession>
    <name>A0AAD5U5J7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Centromere protein C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CENPC1</name>
        <name evidence="7" type="ORF">HK099_007141</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CENP-C/MIF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000067">
        <property type="protein sequence ID" value="KAJ3225223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5J7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019237">
        <property type="term" value="F:centromeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051455">
        <property type="term" value="P:spindle attachment to meiosis I kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028386">
        <property type="entry name" value="CENP-C/Mif2/cnp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025974">
        <property type="entry name" value="Mif2/CENP-C_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16684:SF11">
        <property type="entry name" value="CENTROMERE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11699">
        <property type="entry name" value="CENP-C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mif2/CENP-C cupin" evidence="6">
        <location>
            <begin position="891"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="329"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="400"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="603"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="695"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="333"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="628"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="695"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="744"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="972" mass="113090" checksum="F1603D13DE580487" modified="2024-05-29" version="1">MNGKDAKSNRSSIANIKKGRPNKFLDIGIRGRKTGWEPKKNVKKDHHGYDDPEDFFESDAEELYQETSPNGLNEEVVSSNYSIRSGHYSTLKKLPSVSYSPLSKINALKNETHTFTGSPLKQNQLIMVEEEREEEQQYEKVYRDENLKKTKNIYHDNQNISNNDYIPAKRIVHSPPRQYHDHQNEVDTVRRDNFEYIRSRKQSLPIHLQRSPAISGSSRYHQREIIPANERVKLIQKSRYSLPNKMSDFEEEDYTPQRRSQNVVLDTYESFNVVDDRKPGRIRKQQYDMSAEEEVMDSEHNNFSYSARLSNRQPSRTVQVIEEDEDYYPLYSPSRSTNEPQNSLQIPQHRLSSRNYTNEGIQERKSGDYEREDFDEYNFDYEKQPEDFYNEQIEKNQLLRNSQRQIFNEDNTTPTNKSRRPSINPSKSLNVNSYTRNPDNFLERRRSVNLSHHSRPSDLVYVNSPRIVNNSSVGRHSVPARLKNDQMRYYSDEREVNTSRRSLNSNNISPIVVLSGRRTGKDHSLKSPARSPMYRESSQIDMENDYCDIPNDDADEGDEEVVYIIPKRPSEKKFLSEKKPPPHQLQKNKNTKLMDLKAKRLNKKETVNNKLDQENVLPPNKTSTINHNEPKNEEFQKSDKTEDFSSAADEIHSGTLNENIDNLEGEVSGVEGENYEAIEESEKMYGDEEEAGIHEEQNHSEEYIEKSLPKDEPKNKLTNGKKSEEKRGRSTSSQPRKKGKEKTSYQTLKNSDLGSENANGLRKSSRNRISPIKWWNGECIEYKRIKDEFSGMIGLPKIAEVIRVEDSKDDFHHAKKKRKFIKKENGVENNLREENLIDLKLHDIKFEARNRKTGDTEPMELIISQNKIDWLETHEDFDYAKTFEVDDDYKLKNVSTGFMLMKPGSEKPNRNTKLNTLTIVVVTGKCEVTIHRTTVSVGVGTQFTIPQGNQYKLVNNGKYNCRLFWVCIGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5P2</accession>
    <name>A0AAD5U5P2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tubulin epsilon chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TUBE1</name>
        <name evidence="7" type="ORF">HK099_002731</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000193">
        <property type="protein sequence ID" value="KAJ3222077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5P2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004057">
        <property type="entry name" value="Epsilon_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01519">
        <property type="entry name" value="EPSLNTUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="6">
        <location>
            <begin position="62"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="396" mass="44514" checksum="CCAAABE13EB1EC03" modified="2024-05-29" version="1">MPESIIIQVGQCGNQIGQKFWEKAVTEHASYNKNQIFDESFSTFFRNVDSRNGISNISFEKKEKIVELRGRGILVDMEEGVINQIKNSFVGELFDNNQIISSNSGSGKDKNKNNRNKVLNFLTGNNWAVGYNVYGKEFNDLIIETVRKQTEYCDGLQSFFLISSLGGGTGSGLGSYINELLCTEYPEVFKFSSVIFPAKNDDVITSPYNSVLALNKLINHVDCVLPIENNSLLDIFEKIEKSNPDFSQSSLATNVEELKKNKKLKNFDGMNNIVANLLNNLTSSMRFEGKMNVDINDITTNLVPFPRLKFLLSSMTPLYTLKDVRVAPRSIDQMFLDAFTKETQLIKTDGKSGTYLACALIVRGQGIALSDIRRNIDKISKSLKFVSWNQESWKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U674</accession>
    <name>A0AAD5U674_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cysteinyl-tRNA synthetase class Ia DALR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000053">
        <property type="protein sequence ID" value="KAJ3225768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U674"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cysteinyl-tRNA synthetase class Ia DALR" evidence="3">
        <location>
            <begin position="70"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="218"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="287"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="320" mass="36737" checksum="9946AC0B99E6C23B" modified="2024-05-29" version="1">MEAVKIYNIVHIRILFLLHSWGSTLHFDEAHLKEAREFEGKLNVSWVIQSVLFPFNRTFLLTIQLKQAGVHAALCDSFNTPLAMSELKELVSVSNQYLTEKVKLKGIVNVSLITKAASYVMKMMKIFGVVKTDVQFGLSLNENTKTASNANESATPFIKILADFRDDVRELSQKKADHKHYLALSDKVRDIDLVDLGVVLDDRGDGKALIKFVDRETLLRQKEEKAKTELLKQQEKEKRLMEQNKKKMERLEKGKVPPELLFKDAEGLKLYSAWDEKGIPASDKEGLDLAKSKKKKLIREYEAQTKLHKEYLEFVENENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7J8</accession>
    <name>A0AAD5U7J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_001684</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7J8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051644">
        <property type="entry name" value="TRAMP_AT-DNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="284"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="311"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="360"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="390" mass="45808" checksum="2836A77F7B99B765" modified="2024-05-29" version="1">MFQNYLDDSDNEREFSYDKYNIYSNLNLDKESDQEDSDDEELKKAEEKLLSFTSYGQLQLLKQNQMMQSSSETMDTSNVNLPLEETINITEFPVLKESLPSKVKFDEEQFDTSFFTPSSRYFIDKSTLIKCKFCMKAGHILRDCPSVIIPCNVCRKDHDPAKCSLGEVCFRCGNIGHMNGNCTSVETSRFCEFCRSTSHKTFECCWVWRQYNFDPDVVKITKKPLISCYNCGSRKHFGDECEIYFRNSRSWKSSAFNADAMNFPEWLQATKSENKPDTIFSKYKSTASKSKKISPPPSKRSRRSSPINHEYLNDEHYTDRTYQNKEYPSFPRDAKRNKDRDVDTKREYYQNDKRDKDRTTSYGSNRKNRNYSYDTPLHSTKPNFNSNRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U855</accession>
    <name>A0AAD5U855_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U855"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="189" mass="22153" checksum="52B39EB1CB0A1915" modified="2024-05-29" version="1">MSESRFIICPRTDKNIFITQKTIQNYAATQFSSRDPKNGYQKIVIKRLNGYSCLRFDHHPQPYLGILDNKLCLFEYPTELTYFTVFLFEKRKLPDGEWSSIDPEDGQLNFEASEGFSFKAAFFHIHTKSFLSFNKINKTYEVVPVPLEFNINEIDKSSFHYNFGESLWCLEAVAKNWRLEYGTVAEIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U888</accession>
    <name>A0AAD5U888_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Biogenesis of lysosome-related organelles complex 1 subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001066</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000128">
        <property type="protein sequence ID" value="KAJ3223483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U888"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099078">
        <property type="term" value="C:BORC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032418">
        <property type="term" value="P:lysosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017246">
        <property type="entry name" value="Snapin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028119">
        <property type="entry name" value="Snapin/Pallidin/Snn1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31305">
        <property type="entry name" value="SNARE-ASSOCIATED PROTEIN SNAPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31305:SF2">
        <property type="entry name" value="SNARE-ASSOCIATED PROTEIN SNAPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14712">
        <property type="entry name" value="Snapin_Pallidin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="111" mass="12650" checksum="C75A940AA23D5C56" modified="2024-05-29" version="1">MSIAEGISSAILPLVQELDIKVISIRQAQLELQKEIERLTTALQVFISTSDPPILEKEINRLNSIKKRLNTLLNVLKKVQQRLKNCEKFSRGEELDFWEKIGWGQNSGSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8D5</accession>
    <name>A0AAD5U8D5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">mRNA 3'-end-processing protein rna14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RNA14</name>
        <name evidence="7" type="ORF">HK099_002876</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8D5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045243">
        <property type="entry name" value="Rna14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980:SF0">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980">
        <property type="entry name" value="RNA CLEAVAGE STIMULATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Suppressor of forked" evidence="6">
        <location>
            <begin position="71"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="737"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="855"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="409"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="753"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="855"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="879"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3228371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="906" mass="104497" checksum="E1AFF5B73D7EEA1C" modified="2024-05-29" version="1">MEATSGTEVDYNMNAMDNSTPSATDQESVVNINGSDFSSKVNFLEKSVDSPQQSDFYNWEAENSQKPLFKVEKIKQALKSDIYNDILWEQLLQEAKNTNEEDVIRQAYDEFLKVFPTSSRHWIEYATFEQDNSAFDKVESIFNKCLRSVVSVDLWKFYLSYIQKNHSLTNQDTLQENRTIINNTFEFVLSNVGFDPNSSSIWSDYINFIKSGECNPASYEYQVKIDKLRKIYQQATVTPIANIEQLWKDYDSFENGLNKITAKKFISERSSGYMTARTALREITGFMENIEKAQSSFLPKPVTWSETDCKLLELWKRYIAWEKSNPLNIDDKTHLFTRVMYTYNSALLKLRYFPEIWVEAAKFLISQEKFEEALKLLKTGIETIPTSLLIAFTLVEFEEGRNVAFKEISQIFEKLIQNLESKIDEKNAKFDEEVNNLLKRGNKSVKNNKIADGMEVEDLNEEVWDGESREREREQLKQLEKEIHFKVEETRKIEIDLLKEAVSCAYIMYMRVARRESEKSARLVFGKARKSSHCNYQVYVYSALMEYHCSKDHTIAGKVFELSLKAFLNDAKQAEFVVLHYLDFLHNSNDETNARAVFERAITTLPLENLKSIWKKMLEHENLYGEFNLINNLEKRRKEMYHDNLNIANDLELEDLKDLSKKYSFKDITYIEDEELGIPEQLQHQQPKFQASTFEAKSINRLQTLAAVTPEKFVRPDLTKWQTYKSDPNQKLMVSERNLNSNSPASSPRPDLGNSSPKASHQIPPSSSNTLHTTPSYSQFAIPPAISALLCKLPSPSYFQGPVFNVDDMLDLINKLPLSLPNQQLDWITYVPPSTSDVASGYGIPPFSSSIPPPFSSHSYSSQGFSASHGTSSPAPSSSRRDEHRSRPYDRDRRSGKFLLKNTQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8L2</accession>
    <name>A0AAD5U8L2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Splicing factor 3A subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SF3A2</name>
        <name evidence="11" type="ORF">HK099_000596</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000114">
        <property type="protein sequence ID" value="KAJ3223876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8L2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2690:FF:000002">
        <property type="entry name" value="Splicing factor 3a subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052092">
        <property type="entry name" value="SF3A2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031781">
        <property type="entry name" value="SF3A2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23205:SF0">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16835">
        <property type="entry name" value="SF3A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="10">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="221" mass="25590" checksum="CE6A927766383F0B" modified="2024-05-29" version="1">MDFQNRAGVNHGKAGSSASQANIDRRERLRKLALETIDLTKDPYFMKNHLGSYECRLCLTLHSNEGSYLAHTQGKKHQSNLGRRAAREQKDQPPQVDLGVQAANKVKIANQRMVIKIGRPGYKVTKIRDPITRQLGLLYQIQYPEIGQVKPQHRFMSAFEQHIEAPNKNYQYLLFAAEPYETIGFKIQSREIDRGEGKFFTHWDPDSKQFHLQLFFKNNTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA87</accession>
    <name>A0AAD5UA87_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tau 95 subunit of transcription factor TFIIIC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TFC1</name>
        <name evidence="8" type="ORF">HK099_003623</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3227000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA87"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001002">
        <property type="term" value="F:RNA polymerase III type 1 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001003">
        <property type="term" value="F:RNA polymerase III type 2 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.160">
        <property type="entry name" value="TFIIIC, subcomplex tauA, subunit Sfc1, barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019136">
        <property type="entry name" value="TF_IIIC_su-5_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040454">
        <property type="entry name" value="TF_IIIC_Tfc1/Sfc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041499">
        <property type="entry name" value="Tfc1/Sfc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042536">
        <property type="entry name" value="TFIIIC_tauA_Sfc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230:SF5">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09734">
        <property type="entry name" value="Tau95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17682">
        <property type="entry name" value="Tau95_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel" evidence="7">
        <location>
            <begin position="25"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor IIIC subunit 5 HTH" evidence="6">
        <location>
            <begin position="165"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="519"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="534" mass="61513" checksum="90B98814BEF7C80F" modified="2024-05-29" version="1">MKNSAEQSDADQNSITRLPQMEFFVVEYPGYVNNIDNVLQTLGGIGEIQKGFLKEELPHINLKFRKNDIFSHPVVGEVVTTTNLVLKTVTRRNKLTGNISSTKHEVVGVATKTARFRHIADYQFIPNQADSMVKLAKSLNEWNIEEIENAKLTSDKGKTRYMKTIPPPLFSRAPWAGYYNFRQSDAVKKVIVKEGDKEPEVKLVKRRHNTKNIISHKFKSGEDVPQAPSQKISDNFLLNQTPQVLEIKDLIYQKFELRPIWTSLALFNNINNISSREIKKVLPNVAYFAATGPWRDSWIKYGFDPRVEKSSISYQVLDVRIKKKVHHKTRGGPRATADFYAPDKKKYSAQYVNKDKYFFITVFRSHIFDGLHFEREFGGHYQIADITDSDIKKLIEYKKFASKSFDDKLGWIDRSQYHNLRMLLSRKTKKIINGGISDESEDFKFEDEDVEDEAVVESNSEGENDQGDTQEQEAGDTLMISQKAKVVNFKNMEIDPRINSKVDELMKNLHHASGYGDNMSDDSEDEFDYFDLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT25</accession>
    <name>A0AAD5XT25_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008489</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000937">
        <property type="protein sequence ID" value="KAJ3209499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT25"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042026535" description="Peptidase S1 domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="33"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3209499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="276" mass="29625" checksum="4CFF55765624F3BB" modified="2024-05-29" version="1">MKFSLVASTVLISAIASAPARDDNASVNFAPEIVGGEPVESQLIYPWMASYSMFGYDHYCGGTLIAKNLLMTAAHCNPTGNVGNVKSVSSFRYDFTKTRAQEKSIEFKVEKIFNHPQYNQGGTNKNDISIWVLKQASNPANRDVVYAKYSKSIAEPPLDLNIRALGWGATRQGGSGSKVLLQVDIPVVPNAECNLQYPGQIFESSVCAAEVAGGKDSCQGDSGGPIFSLNESGDVTVSGITSWGRGCALAGYSGVYSRVGSHTDFIQSYIDQYAQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTL7</accession>
    <name>A0AAD5XTL7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tryptophan synthase beta chain-like PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007509</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000732">
        <property type="protein sequence ID" value="KAJ3213226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTL7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000006">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="9">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="137"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3213226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="271" mass="29193" checksum="C850F70BEB95D294" modified="2024-05-29" version="1" fragment="single">SVKDRLAIAVIEDAERKGLLKPGQTVIEATSGNTGIALAMVCAVKGYPFVSVMSESFSVERRKLMKYLGAKVIVTAKELKGTGMVEKAESLAKEKGWFLTKQFENPANPEYHSQTTGPEIVQDFVGKRLDYFVSGFGTGGTITGVSSVLKVARPEVKIIACEPESSKLLTGHEWSPHAVQGWSPNFVPKNLNTKCYDDLIYISDKDALETSRELAKKEGLFVGVSAGASVFAALQVAKNSPPGTTILTVLPDTAERYLSTPLFDGISVDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTV8</accession>
    <name>A0AAD5XTV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000676">
        <property type="protein sequence ID" value="KAJ3213796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTV8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF1">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOMON" evidence="2">
        <location>
            <begin position="29"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="280" mass="32009" checksum="4C60162A9E22A3AD" modified="2024-05-29" version="1">MKLNTILKYVLISTIFFTRKTIQEGLETECFKFYINELFEENKFKFRVEANFYVSWMAIGFGEDMGKAEMYVAHLNGGTGSVNLTRRISTDWVKPKVAINQDFTLIESESGLQDEKLLVTFTRDFKSTFAEGVEIDFIPNVNNNLIWACGTKPFHKDINYHQKFGEIEGLNLFNVKLNYNQNNIKNNNSISKVDSIFNSWENDDSKNNVNRVVENINSTNLNNTGILESAGDEEEEDDDDDSETNINFTHGGIMIFSWGILFPIGVASTKFIQVFSKTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTX6</accession>
    <name>A0AAD5XTX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000646">
        <property type="protein sequence ID" value="KAJ3214143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTX6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="248" mass="28337" checksum="8AB0DC351F8B31C5" modified="2024-05-29" version="1">MLVSGNPHLQNTTMSDLKKKAIYWRKKFDNLNCDDINTEKVHENGGWCLKDDPSSDKAAWMGARPALHHVPVDHGVASTVAKHLTSGNTREISLIDIGAGVGQYGRYFKRNCPTINYKGFDGAGNVEQFTDNFLTWIDVTDPAFDTIGEYTADWIMSLEVGEHIPSSGTDNFISLLDRHSRKGVILSWAVVGQHGHSHINNKDNDEVIKLFKERGYYQDDWTRKFQEEAREKAKYWWFKKTILVFKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU33</accession>
    <name>A0AAD5XU33_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KIF11</name>
        <name evidence="12" type="ORF">HK099_006885</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000622">
        <property type="protein sequence ID" value="KAJ3214419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU33"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000073">
        <property type="term" value="P:initial mitotic spindle pole body separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047149">
        <property type="entry name" value="KIF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970:SF12">
        <property type="entry name" value="KINESIN FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 8 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="11">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Kinesin motor" evidence="11">
        <location>
            <begin position="191"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="308"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="561"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3214419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="988" mass="114258" checksum="265346805EA110AF" modified="2024-05-29" version="1">MLEEVLLGQTGSGKTFTMEGDLSDVQGYNAGIIPRTLYQLFNRLEYSKTEYSFRVSYVELYNEELKDLLSVDEIATDTTKPEQKKLKIFDDLNRKGSVLIQGLEEVLVKNCEDVISILQRGASKRQTASTKMNESSSRSHCIFSITVHIKEATSDGEELLKIGKLNLVDLAGSENIGRSGALDKRAVEAGKTKTCIIAAVSPAKSNIEESISTLDYAHRAKNIRNKPEINQKMTKKTLIREYVNEIERLKADLNATREKNGVFMSQQNYQTLMEDNLCKSDQLEDFSKILQQKEELFNILELKHKENIQLLSEKNVLLDIANAELEEKKIGLRKALDELSVIERRFREQKLLSNVYAKSEKRLHSLASGLSLSLDSTVNDLEGLFNKIERKKNLENDNLFLFKHFQLDLLKKIQSLDEILKKMKNHSLNYEKNLELNLYDLVNVEENNSSNYIIWFNSFLNKLTSFQVKLQVNKKNEHTTFDSIFEEFMKDLKNFAHEVGTSLTEIDNDNAKCTKSFDHIFKLFEAELSSWMVNLQTFLRNYLECEQNDTEKQFQLCTINNQNLHRDIDVQLEEIKNENTKLRELIKEERIKSKKRNEDIKRNFLAALEQIEHENEETLLKISNIDNESSERNQAKLNTLKTKINSFEEELLLNNTKLKEVYASNLCILEESFKYGFEKNKESFESLKSNFCSHQDALKQNLLQFTDFFRKSVGKFDAHCEKGLKTGEEFKIQFEANLNENKNFFEKQKSSFDDTIDESHTNFTLKTKEISNLILENSKTCSEIIDYGLKENIEELTKEINFNKLEVDRVTGYTPKKKFINVPKVWKLAAPHTVILSKYRKRKGLDEDVFNDEEINSDDFRKISLISNNSKTYSDSFLGVQDANFKNIDMDSEEDVDSFFVDVEIEPNTQRSSNIVLNEESTNAEVNFVENSENMNCTDSNVSTPFKTNIISSTGSLQQQKIISKLPRALKRNMQDTPFKSRVENFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUN1</accession>
    <name>A0AAD5XUN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000480">
        <property type="protein sequence ID" value="KAJ3216404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUN1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="55124" checksum="6727E27AEB25FB40" modified="2024-05-29" version="1">MVNRLLQEYIEKYKTEFGYVQQNVKYIDQIALYQSVKVFTNYSVNIQERFVPKVKTFITQMIIKKQAKTIPKNMEKKDWVKNLQARNSIVISIRNILPDTIEKDSVAYDVHNTKKYFEAYYKLGLLYEEYNLKEFNVFPLSTSTIPRHIRFDTNILIKAILNLRGQLANGNLSVENDMDYIWNTLFNLKKKPFKSRSGMVFSGCIETDGVSVSICLEDIATHNKKKNRKGKKRKKPDVEENEPVKKTKNLDKKKTQNESVKKTKKLDKKDIPSEYFQENTLKENHVYIDPNKRDLLYCLGSNGEKLRYTQMQRRYETRSKKYSIIRKKLEEHNVNLYQQNVYGKNGLRNYNLPIPSRKLLDPIAYHGVNTTVLIGDWSRTAMKYQVPTKGKGFREMFKKSGYQVCLVNEYLTSSICPGCKTRSLEKFKEPPNPNPSKNGKVIEIHGLLRCKNENCEQMVNGNAVRDFGIGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUS2</accession>
    <name>A0AAD5XUS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000453">
        <property type="protein sequence ID" value="KAJ3216912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUS2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="274" mass="32067" checksum="AD6BE994845A79AE" modified="2024-05-29" version="1">MHGLINKSPHSFKPIEKTFTCEWDVCDQQFNTEKNLFYHVITHLPEGRQQCKWRKIEKLKKSGTCGISCRHKGYSMDHIVSHFSHQIRPLTCSQCALTFRNRQDKRKHEIKFHNKLTNKAVNKYPQDLLTKTQILSTPIVASNLAPNNTLLREVNYNSFSDIQNSSQQNLKEVHSFNAGLHQSTIVKSNNFKTSKLPIILDGTQYFPYNRMSRESSEVVYLENQPQMKGNFATDGQKMQQLIELKDYPSHFHMLNYNQYSTQCNIQDNKYNNFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV14</accession>
    <name>A0AAD5XV14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein artemis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DCLRE1C</name>
        <name evidence="6" type="ORF">HK099_005297</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000404">
        <property type="protein sequence ID" value="KAJ3217926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV14"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF8">
        <property type="entry name" value="PROTEIN ARTEMIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA repair metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="149"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3217926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="459" mass="53157" checksum="297C7AFAD13FFE96" modified="2024-05-29" version="1">MVFVEGYAGKILYTGDCRAEPNFIQNFDNDIFKNLKNLYIDTSFCHKSYKNFPLKSESVEHLINFVEKKPKTSRFLLHMINLGYEELIIGLFEEFKEKVFVSKERYALYRQIPLLKDIITTSNEVCSRFHCCDWCNNCKSLDKQKDGKFFSLKPVCRNWDYSSIMDNDESVNNTALILHAGGNRYSICIAMHSSLSELQKFVSLLQPGNIVANVVRETDLPNKDIMKLLSSFTTIKKRETAKTLEETSGQFLTSDRRKEKEENINYKQLEIEKLLDLEFQNVIIGNGLDKTSSGFISSSERKRKLSIHSDVDTEIMDIVDTTKKNLEPKITDEQEIHFDVDNVIDILKKVERPLMKDYLSSSSVVNTKLNDFIVCSEKKNGADYAIDSVSREKLRKSYQTEELVSEKGTETLKKKLSNNKKVTDLNLIQKVDSKIVQYFENKFKDKTLNFEKNFVNLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVQ5</accession>
    <name>A0AAD5XVQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001635">
        <property type="protein sequence ID" value="KAJ3202017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVQ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="244" mass="28526" checksum="B2ECC5DD8AD898E9" modified="2024-05-29" version="1">MSKQQPNKFLDKLTNCYTDEELASYQDVKGAQIKLEPTHSGDNEAKEPKVEESNEEKVKQPDLSVEQLLILLNVRENEMQRLKIQNNELISQLSVPAPTLSERPENTAAVNKSIINMVFELAKVIPEIRSSYTNNEVFNHLEQFDTYITTAKENSLYHDQLCVMSSFNKLAESHQIQCKLHFDVKSDWIKVKVPKYREWLEDYFKVYEAADTYRAILLNSSTKQTQFSQFYAYLCTLVYWFWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVU5</accession>
    <name>A0AAD5XVU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001538">
        <property type="protein sequence ID" value="KAJ3202652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVU5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="335" mass="39109" checksum="E2436728E5BC09D5" modified="2024-05-29" version="1">MKAWEYLIFEHLYIIKGKRINPLNKSFDPVKSEGWDDFISKPYIGQGCRFFRRDIRLWVSDSKVEVAKIFKNVSKAAVPPEVLLVLKQLLSFEQNYDKLEEIGLFERPPSDADLELEAERRLNLMKSFYNPEEEVWTDHEIVQLKRTGIAKKEVGTLKRKSELMLEDKRINKFQKSSSVSSNVSSSDTEDDDEEASEDDFIMEEDQISAEIRKLAGKENPQFALKESKKYLVENISQNCDEKNDRNKSGKSIAKNLKISNEADFTFKKLLQILPLPTLNNELEEKYTFYLQKKESPLLESKEDRQEVIFDEKDNCSLKLKTGDNLFIKREIIKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW47</accession>
    <name>A0AAD5XW47_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000811">
        <property type="protein sequence ID" value="KAJ3211829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW47"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1070">
        <property type="entry name" value="Head and neck region of the ectodomain of NDV fusion glycoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3211829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="219" mass="25647" checksum="7E141B5A949250E0" modified="2024-05-29" version="1">MNFSKVLRSGKKTDTISPKQQRKQKLQTLSKQASNPKRPRDNLLETLITFNDKIEDEPEEKKRMLSYKVTDSSVKYIESQDTVEARLNHVEDENKEIKQRLDKLENRVYSLEKWMAKPCLHTALETTFKKKMKTPSTNRLGFFDLLNDCVESDILKYTGIDKATWIGMESFLNTRPNSRNDIVHHDIPDNVLVEDCFDSLKATMDEPMKRNFRSFLNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW68</accession>
    <name>A0AAD5XW68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000241">
        <property type="protein sequence ID" value="KAJ3221249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW68"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="648" mass="74042" checksum="78426DAEFF289A4C" modified="2024-05-29" version="1">MQKSEEEEEEEALVIFIFSDYYTIGNSQKRFNKDTFKSFLDSLLKNSTSAIIPPQYIVNNVFTIKIKTIDLITLTYQKILPFSEIKDLGTDFKKSEQLNAEQQQIVNQNGKIKEECNKIDMLDLEQRVLPILYPDIELNPKKLNSLNVEVFNELKYNKFSNNFTKHNLKQKNYSHYNKTLKNQIKNQQVEESNKNSIQKAEKIKEKIEQEEDDLYFLLNNSSGNNVNLNLSQNLNPNHAAMNAEGINHQSNSQGISQGTTNQNSQLNNNINFLPSFNLLAFIQQWKQRKLKDNAEPIIGAENIKSNKSNFNQRFVGGVLNEKKVVRTLRYKQENKYSKKEVFFVLNIYEVLDGSEYEAVFRIGDVEGTCQGEFGSELKFPIGNLASMELFVAHFKGHAKFDKILSSDVFIPKTGSQATSTQSNPSGLTSQAQQQAVQQQQLQQLQQAAQQQPSSSIQQQPLNNLLQQVLPTGTVNPGINPQIMQQINGMINQNRVRPPTTLTGQQGLVNNMPRFLPTGQINPNNPAALLTQQQMQQQIAQNSFYQQQVHQQMQNANPHNQQQILQFLQQQQLQQQQAQHLMMQANLIQQQLQREGGTQNLTPAQLQTLQQAHVLQTQVQQRNQQLQAQQAMFLQQQQALNQINNSNNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW73</accession>
    <name>A0AAD5XW73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS26_3</name>
        <name evidence="6" type="ORF">HK099_003652</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000240">
        <property type="protein sequence ID" value="KAJ3221268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW73"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1740.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="117" mass="13422" checksum="41E4E5B7A6208402" modified="2024-05-29" version="1">MTQKRRNNGRNKQGRGHVKPVRCGNCARCVPKDKAIKRFLIRNMVEHAAAGDISEASVFQEYAIPKLYIKMQYCISCAVHSHVIRCRSRETRRNRAPPPRFRAFNKDGQQKKAVAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW90</accession>
    <name>A0AAD5XW90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PPIL6</name>
        <name evidence="6" type="ORF">HK099_007697</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000770">
        <property type="protein sequence ID" value="KAJ3212635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW90"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="163"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3212635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="326" mass="37557" checksum="1D7F8DA3409FE3EF" modified="2024-05-29" version="1">MSLIKNKVGTTTTIESSKKKSDIEQTLTEVSLYGCVRHPQFIIAKEILESLYKTLPHLFTKSDFNLIPLCDLEYRDFRHKKKKQANIVDNLFPSIIVQVEKKLKINNNVEKIEHFNLPDFLIYLKKTLPNFNFETEKSEEEYNNEAGILFLKTLGKLENPLVFVNISIDNLHAGKIIIELFRDKVPKIVDQFLSFVEPKDSNGPSYLNTSFSRLVARGWIQGGEIMKVDEEGIEELICEPLVEDENFIVKHDRRGIISMINQGPNSNVSAFMILLSEGMEYFDKKYVAFGRVLEGEGTLNNIEMVETRFERPVKDIKISEIGIYRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWB8</accession>
    <name>A0AAD5XWB8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007561</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000743">
        <property type="protein sequence ID" value="KAJ3213129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWB8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17270" checksum="A1421DEF06D02179" modified="2024-05-29" version="1" fragment="single">MKAASLVSANAPKSKYPKLYNTHLQVSHPFKAYAQKSILSLKDPFENRIKVKSEQFDLLQSKTTKSEYVSDIPLPGALKRQLIFQSPPLVDNTALGKIAGYRIQVTGRRGSRTSKQVVSYGKLESRAVGENPLTFGRYFFNGKKGTTGVKVWVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWN3</accession>
    <name>A0AAD5XWN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000185">
        <property type="protein sequence ID" value="KAJ3222227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWN3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="670" mass="76445" checksum="6F1C9B62105711A7" modified="2024-05-29" version="1">MTNSFILAVPFASHLENYYENHLNQPAANAKHSVDAETKLSDNFKFEVSMKGLEDLINFLNFLHNKLNDDEESDDYLWKNSIDYKPTDLTTTEIPPIQANSTTAVGTDAEDETLKDQDIINFSNKKSKEIFFDDYDDTFSNVDQELKPMKGLSELRKEDHLGYIKSIYKTPSQPPQHFQLFDIFDASPYSILSPLLRPQTKPSAPVDNSDFLEGLIPKPKVTKNLSVKKQKRKSVKVSPSTSVFKEGSINQQEDTDLTSIDNDTTLIEDSFEEAFKEVTVVNKIISTPKNQDTKLGKNSNLASEKITKPTNSDVLSSKNENTVEKKIEKVIEKNITILSKEKNNNAAKKQQEKENSFNHLKKNILKQDFKNKSEITTISTYKTTVTTTTKTTEEEVKVVEKKVEIVEKDVSKNIKFGEILVPENVKDHKKKERFSKHKKEKKPKNHFCYQTDDDHYNNESQQSKKQDVEKNQIDQLISHRNLNETTIVNEHTKVNDTNGQCNVDNTTFNNSNKMINEISSDNSSNNANTVIFQATEEEFEDDQKVNDKNTTINAISSDNENQSYDLIKKKIDKIYFGEILSSSFEVDFSTPMFSGLKKMQRRIDSKMNLLNVDNAKPHSTVSQFLLDSNANGENWEVLDLGYLDRSTFCGFNVGMDFNNSSADKFLLNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWP0</accession>
    <name>A0AAD5XWP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">HK099_002695</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000191">
        <property type="protein sequence ID" value="KAJ3222116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWP0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08831">
        <property type="entry name" value="ArfGap_ArfGap2_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23285">
        <property type="entry name" value="beta-trefoil_MIR_PMT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000004">
        <property type="entry name" value="Putative ADP-ribosylation factor GTPase-activating protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF51">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="15 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="592"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="636"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="663"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="708"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="23">
        <location>
            <begin position="311"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="23">
        <location>
            <begin position="389"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="22">
        <location>
            <begin position="767"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1077"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1141"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="1045"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1078"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="20">
        <location>
            <begin position="1141"/>
            <end position="1154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAJ3222116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1276" mass="144251" checksum="0CCD5D5E58792BE7" modified="2024-05-29" version="1">MSSEIRKRNSSRSRDKSNERVREPSPDRKSFDQLKKERVILEDIRSSGGGVIHFGKFASYYLERTYYFDVHPPLGKLLLAAGYDGHFHFDKIGDKYLENNVPYVGLRLWPAFCGASVVPICFLTMKEMGFSFPGALFGAALLLFDNALITQSRLILLDSMLLLFFVMSGYAWVKFYKTRHNAFSQEWWLWLVLTGISLSLTIGYVDAKIFEHLLTSKFRVKMVGLFTFGSVGAAVIIELWDLLDYRKGLTMRQFGNHFAARALCLIVLPFVLYLSFFYIHFSVLIYSGPGDAFMSTTFQQGLLGNEIATKSSSIPYHANVTFKGRAYSVYLHSHIDRYPLRYKDDRVSSQGQQVTGYPHKDVNNLWEIYPVDDSEKPYELDELEVKNGVRYVKEGDTVRLRHVLTNSYLLTHDVASPLTTTNMEMTTWPANDTSRFDDTVWLIESSDVETSSYLKSKKDLFKIISKKHKVCVHSNKGTLPEWGFKQQEINGNKAKKDDPENLWAIDEVQHERIVNGTEIGEEVEAVEPQKKKLSFLSKFFELQRLMISHNSGLTKPHPYSSTPITWPFVLRGISFWENKEGLRQIYLLGNPIVWWISTLGVFMFPALWLMDRLFLQRNIDDFGLHARRWFDRSVGFLWLTWALHWVPFFIMGRMLFLHHYLPSFIYSTMIAAGVFEFLGRVVNQIMPLHVMQNKKAPIGSWLVTQGSAYYWLFLLLCGLFCLASAYYFAPLTYGSGFPSIEALRGRKWFESWDLQLMSLTLEKNEINEIFKHLQKQRANKVCFDCGAKNPTWSTVTFGVYICLDCSSVHRNMGVHISFVRSVLLDTWSIEQLRVMKIGGNQNATEFFSQYGGTGKFQDGKSKYTSRAAVMYKDKLKKLVDEDELRYPGRIVFEDVAVEVSTSVAANQDDFFSDFGLNTSKGNQVTQSQPVFEKRQLSFGVATAPVKQNQTSFSSDGNPVKQSGSVSSFNSISSEPLSVNLSTSQADDVFNNVNNTFGSTATNQKSFQSVHPAYSQSNAPSSVTSTSFLKANKKSLGAKKATKTINFDEAERKAKMEEEKRKLEEVELKNRELEDVTRHFTTPSKSNSDFSVKSLNSNRSGYPDTSKVANGNNNDEMMDRLGIGFGKLNTISKNTTSNSGGFGATGGFGSMGGGNSSQEETGDATKRFNTAKAISSDQYFGRGNYDEAAANEARDRLRNFQGKSGFGSSDYYGRDESRPLNAAQGGDVLGDVGESAREFASKFAVQAQEDLNSLKRVVNVGSQKLGEMLSDIQNRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWX0</accession>
    <name>A0AAD5XWX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001596</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001467">
        <property type="protein sequence ID" value="KAJ3203159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWX0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF6">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0868">Chloride</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3203159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="52789" checksum="569C7482A8F93AA4" modified="2024-05-29" version="1" fragment="single">ISEISTRFEQISPRRVAYDNFTTIDWNYDFAKDRIRKRTLKRRIGIKARLAEYYDHFQGWILVLLVGIITGFVAGFIGITAEWLSDVKDGFCLDYFYLSKGFCCLDTEFNQECAGWKNWFEVDSVNNIYGSVLNFLGGYFVFIWFSILFACLSALLVKFYAPYAAGSGIPEVKTILGGFIIRRFLGFWTLLIKTVGLCLSVASGMSLGKEGPLVHVACCVGNIIPKFFKKYANNEAKRREILSCASAAGVSVAFGAPIGGVLFSLEEVSYYFPYKTMFKSYFCAMIAAISLSLMNPFRTGKLVLFQVVFDRDWHEFEFPFFILLGIFGGVYGAFFIKMVSALANNVKLAKIRQTSWIKEWAIMEVIIIALFTAVVSFPFNFLRVNSTELITNLFRECKEIEGDFFGLCKFSNSFIIIFMLLFTCVVKVLLTIFTFGLKIPAGIFIPSMTVGACFGRALGIIMQAWQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX80</accession>
    <name>A0AAD5XX80_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX80"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10827:SF85">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10827">
        <property type="entry name" value="RETICULOCALBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="13"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="84"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="121"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="155" mass="17714" checksum="488FD62E1EF78F06" modified="2024-05-29" version="1">MSKLTPKYQVDVSDKASVEKAFKQFDYNNNGLLSLAEIDKAVIEILPQFAKDKPAIMRAYKAADKSKDGFIEKDEFVSLIKLLNHYDSLFKVFQKLDTDKDKRISLKEFIKGYELIGLDTKDAAKLKSEFEKIDTNNGGYILFEEFCIAMAKKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXG3</accession>
    <name>A0AAD5XXG3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000751">
        <property type="protein sequence ID" value="KAJ3213062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXG3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036149">
        <property type="term" value="P:phosphatidylinositol acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="63"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="364" mass="42005" checksum="3999631D043D16A2" modified="2024-05-29" version="1" fragment="single">MLANCIQLPSYILYILNYKLFRKVNSSLQKAYGSLIVILTWMFCPLELVLTGDFNELLEEDNTVVMSNHLIYSDWWYIWILSWVSGKHGNIRIILKNSLKYLPFFGWAMSYFEFIFLTRKWVADKANLTENLSKCKSNNLPIWLVIFPEGTVICDETIPSSTKYLKKMNWVEKYPLSNVLLPKHTGLFHSLDILKPKSLYDVTLSYSGVTEGKFAYDVYPLAKVFFKGEGPKRVYLNIKRHDLSSIRGFQSEVAEGGGSNVSERSEEFGDFLREQFLLKDLQLKNFYSHQDDSSNDIDEAIHNQQQKKIIKCTPKIKDFIFLGLILFTCCFTLNRILALLKISLSIKQTGGLFGTSILAILIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXI1</accession>
    <name>A0AAD5XXI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000114">
        <property type="protein sequence ID" value="KAJ3223869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXI1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="363"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="397"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="545" mass="63361" checksum="2FB1D1BAE14FF43D" modified="2024-05-29" version="1">MKFFEEEEYGTTNNIDNLNAFNANTDLATKKFNVITIEPSSTTTQLRSTLDQSEVEEDLVEKATTSLTEAIAELRKQHDEIQVLKKDRMFDDEITEKEMEIIEKRVKLQQEQFKEFQSRDLKRKYKRFKQEWEFLTLEEVELALKETNENEEQAFLNFTDKTYIAKIRKNLCLNGSDVVISEEVKLEREKLVKRRVNLVKRVASDALKNKGSGRFKGARLDVALKQLENCEDKEEVFSGWSAARTTAYKAIDTNPNSYYYRFNAPGEKQKNGQWDALFMARLREWGEVGQWGIFSQKIPGRVGYQCSNFYRLLLKNGEVKDENYYIDEEGQSHYLFGKKEGKEGVVRRNSKHWKEENKGKVGINNSCNNSNINNENTKFGGVKKRKSRSKLKKNIHEEDEDIDMEDEIDFDEFDSHYSSSSNNTGNPSSHNQTLGSEQDGKDESGYQPLKNPKRLKKDNRCEKVFTEKNLNPLPGFIDPITLDEVIKPAISPFGHVMSYESWTRCLSDPDRKNICPLTKKSLTKRELVVLTHENIEEYRDKIVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXL8</accession>
    <name>A0AAD5XXL8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000104">
        <property type="protein sequence ID" value="KAJ3224111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXL8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="189" mass="21441" checksum="E1CD79BAC5DD1785" modified="2024-05-29" version="1">MSQTRLNSSFSGKSSTKDLNSSFNNLRKQSKVSINFKDLQFKGKGLLRNYEQEEDIPHQNMKLSITFRILTALTAIAVFLTTALNKFVDISWLVTVSFFVTTLTIINFTVYGIALKFRRNSWNFIIIRFILDAILLTICLNLWTITHKNEGPLSALDLNVSGTNETLLDLRDRNIRKKSAMQLAAAGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY08</accession>
    <name>A0AAD5XY08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial fission 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FIS1</name>
        <name evidence="11" type="ORF">HK099_007646</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Has a role in mitochondrial fission.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FIS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000076">
        <property type="protein sequence ID" value="KAJ3224926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY08"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008835">
        <property type="entry name" value="TPR_repeat_11_Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3224926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="147" mass="16724" checksum="5768AB8C2E863F75" modified="2024-05-29" version="1">MSYLPTKEESEALVGSNELATLRQEYEEDQKDQQKKFNYSWALVRSNTRKEQEIGVLLLHEIYKQNTSRRRECLYYLALGEFKLGHYTEARKFTETLLQKEPNNPQAVQLLQQIDDKVKSEGVIGIAIAGVAIAAVGLLVGALTKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY14</accession>
    <name>A0AAD5XY14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Iso-1-cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CYC1</name>
        <name evidence="13" type="ORF">HK099_007590</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000075">
        <property type="protein sequence ID" value="KAJ3224961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY14"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 9 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="6"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3224961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="108" mass="11809" checksum="6B62989A44210BE9" modified="2024-05-29" version="1">MSFKGGEAAKGAKLFKTRCAQCHVVEAGAAHKVGPNLHGLFGRTSGTASGYSYSDGMMKKQVVWDEDQMFTYLENPKKFVPGTKMVFAGLKKEKDRADLIVYLKEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY22</accession>
    <name>A0AAD5XY22_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ERG10_2</name>
        <name evidence="15" type="ORF">HK099_006864</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000062">
        <property type="protein sequence ID" value="KAJ3225406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY22"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000007">
        <property type="entry name" value="acetyl-CoA acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF156">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0630">Potassium</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="13">
        <location>
            <begin position="18"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="14">
        <location>
            <begin position="279"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="11">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3225406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="41902" checksum="B20D78D572C6EF66" modified="2024-05-29" version="1">MMLKRFLSTSSKLNNKSVVFLSAVRTPVGSFNKSLAKVSATELGSVAIKGAISKANLKPEQIQEVFMGSVLQANLGQSPARQAALGAGCPVTTEATTINKVCASGLKSITLASALLEAGHRDVMVAGGMESMSNVPFYFPRNHGYGHAQANDGIVRDGLTDAYDKIHMGVCAEETATEHKITREVQDQHCLSSYTKAKNAWEKKVFAEEIVAVTIKSKKGDKVISEDEEYKNIDFAKVPKLNGAFVKGGTVTAANSSSLSDGASALVLSTEDFAKENSLKPVAKILGYADAAVPPKKFTIAPSVAIPLALTKAGVPLKDIALFEINEAFSVVARVNEKILGLDEKKVNINGGAVALGHPIGSSGSRIVVSLIHQLKSGQIGVAAICNGGGAATALVIKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYK3</accession>
    <name>A0AAD5XYK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000486">
        <property type="protein sequence ID" value="KAJ3216293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYK3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="460" mass="48957" checksum="60EF92BC4C5FA19A" modified="2024-05-29" version="1">MEFISQKASQAYTAVHDTIIPKQHTEDEQKEDTFYDAEDRKLGDSLTKTDDYQRDTGLDNTRNFTEDRGVTDVHGVSPPLYHGYSETKERVLSPGFNPDIAPNSDLHKPTSKNLGTDKQSSIKDSAYSGLQTAKSYISGGTQKIGSVLHSAVAPSAEHSNVNKDIHKQSTGSEKKSTIKDSAVGGLETAKSYISAGTQKLGNVLPSSHSTATKKNTASETVTPHTTTEKKSTVKDTAMSGIETAKSYISAGTQKLGSVLPSSHSAATKKNTDSETVTPHTTTEKKSTIKDTAMSGIETAKSYISAGTQKVGSVLPSSSTTTQKSYAPEGISPHTTTEKKSTIKDSALSGLETAKSYVAAGSEKLGNVLPSTTTATKRSSNVGDVNVKETETPGPEGKSTIKDSTLEGLQSAKSYISESTQKIGDTLHSAVAPSAEREVVYKPEHKLEEDVVNSRNYVTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYM9</accession>
    <name>A0AAD5XYM9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYM9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="25"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="131"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3226772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="301" mass="33845" checksum="6A71ED9F316CAD09" modified="2024-05-29" version="1">MASTSSPYIPNTTAPISKKIVESNSQSAFIQKLYNMLEDAEIQSLISWDISGTFFLVHDPTEFSKIVLPQYFKHNNFASFVRQLNMYGFNKLNAGVHLVSNATGSPTDVWEFKHPDFKRGDIHSLQLIKRKASKSNANGNNNSSTPKLPHMYDDSNNQNNANKDEKINFLSHKVAELEEKLDKLHESHNLLWSETVACRVLQSKHHQVIGNAISFLASIYREENANSDSRSKKRKLDVDVLQAEVAKLSDHTGSPASTQQTQLMTPTSNQTVLSRDVSDQGFFSSSSNLNDSQTTLFRQDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYQ4</accession>
    <name>A0AAD5XYQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000040">
        <property type="protein sequence ID" value="KAJ3226268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYQ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001650">
        <property type="term" value="C:fibrillar center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001164">
        <property type="term" value="F:RNA polymerase I core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038801">
        <property type="entry name" value="TAF1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15319">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15319:SF1">
        <property type="entry name" value="TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="978" mass="113179" checksum="1E41C380F6428FC1" modified="2024-05-29" version="1">MFPISTPVNIKNSSQTTFGSLGNFNLDFDPQFLFHNGNYNFVKTLCSTSTANGTHLNALVSKRLSSFTRSWRLPRFPSSILSSGLAQSLRCKNLDPSSHEIEQMVGYWSLVDSTQYIPHQLLYNNLSEGLKFEYQNYYQFPYLRSCTSCFQLKDKHWIAYASGTLLNELRINLATDFQDAFASSLKLKRSILQIVVSEVKVSELCTILAIRTEKMVSFISVNLLDGVNLSMEIFKAFEFEENVVDVNFCNTIAFEALILLKDGTVCLWEADTIEDPSVKIILKMKNYPANEWLHCFFGFQPESLVIVGSSRIEKCDFKRSSSKSTLLIYRFDDDEKNEKIQFGCSGGRILPFKLLLATNFGFKLIDIRHPKKVMLEWNDCDLSETVAGIELFKLPNIGVLNQVGVVTWNRKNADIIFRIIEIVQHGNALKTNGFSQTIKPFFEFENYKYFNDNPRNVIPTLVRQTNRTEKKYLESFPNVKWPPLYGVSIFEDDNSIITIFQLVYDGSLYSQQFILDYTSSKISEEYRTVIEGSIEVSEKKKEESLQHNHKSGDNKITDKSNFLDVIKFRDVKSDIKIKFGGFNTNIFPPRALSTKMNFKSTPIYQFQNLWKFLKGFIDPSNPYYFQEDNLISFNDVLQEKVEYWDELALSGTVKLIEYRNMVPVIPNSYPTNYFTSIEHLNDFEKIFKSKTLNLSIQSIPLFFLNKYSHNRNNFTSTNFNSLEELRNFLNGLFAVQDEQVTDDFNAYNGEIVDFYEYSRKKSIDIATIEIFKSLKTFNITTRFIETQDDTLNEEIHMERIGNREVLLENNFLKADSSDEEEVVPSPQILLKSHFTSYPVKLSKASSELYHRWLNPEKYYVKRDYFRNRKDNNDEELKGVKKSRRKTMIYQEKMKQKSDLNLQNYLLSQQTQSQISNVCSNGEELPTSYQLPAVLSASQNFVIHNSVNSLSFSQNSGTSVLLGRQSQKDTGKKKRKRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYR1</accession>
    <name>A0AAD5XYR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000240">
        <property type="protein sequence ID" value="KAJ3221267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYR1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="120" mass="14317" checksum="4B737E38C139FBF4" modified="2024-05-29" version="1">MNKSIYQAEFLDSLKNEDFLKAKFLLKKMEIENRDKRMTDEENYYHFSAEEEEDPEEEEENIFKTFGRNFAKKQQNSKTNTLNSSIKSNSSHKEDLKLVMLDLLDLLEELDFDDSILQIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYS6</accession>
    <name>A0AAD5XYS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004981</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000037">
        <property type="protein sequence ID" value="KAJ3226403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="WW" evidence="5">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="288"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="6">
        <location>
            <begin position="498"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="437"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3226403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="581" mass="65713" checksum="CF3F13D1C2EA7228" modified="2024-05-29" version="1">MIVTLGIASFDYEAIEDNEISFCASDTIYITEMCNSDWFTGYTDPNRMVLGVKVTGQQIIVNQLDSNASENIATGDFDADTNIENFGNSNSFNETQILNVASRDIPVVDFTDNKESIDNLLSTEQVDKINSPENNEKGKLEETLVDLTVKASLNEQPDDNLPPFTALSNDVWQPVQNDQGQTYYWNPTTGETSWNLPNEKDSVENEAYNDLEWTKAFEKNNSSESLPEAPMNLNLEVNVDDHKEEEDEEEGLNFSEMNLDYFNFIPNEYIKKQGMIGKKFKSKAKNNELVASGQQQEVSAVSGMKKKSTWKNYWCVVVVGFIFFFKHQPGKSKKIEKPKSLIKLKSFVIENASKTDSKKKNVFSLSCVENNGEDQFLFLSLNESDMLSWMDCISECFVENNAIKEVDEVINLIFVKNPILSSEKKSTSILMKIPSRFRSSSGGSEQEQQTSSIITPQQSKKSSKFGFFNKKNSPSNSNVNQSSNSHSNIIDYNKYNNLELEKVFENSLESQINFEYHIPKIVLDCVKEVEFRGLLSQGIYRLSGTSSVIKDLKAKYDRHEAVNLSEESLDINAIASLLKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ16</accession>
    <name>A0AAD5XZ16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000566">
        <property type="protein sequence ID" value="KAJ3215127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ16"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="190" mass="21929" checksum="753F72E70A93AE9F" modified="2024-05-29" version="1">MEQLRSKKDDHLFITDPLNPSRYDDKLISKNLENQGYQLPHHFTQANTSNSNTSKEPKALSMSTFVDQDRSTKKNKSKNYSTGSTRENKSEKYSMGGCNYNWDECCNRTYESTHKSSMGLFKNNKKERIFNSDPLVPPRYVDVVASTSLQNQEPESISMTTLADKDLSEKKLETESTKNKCCNDWYLAFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ30</accession>
    <name>A0AAD5XZ30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ30"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF26">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="348"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="656" mass="73908" checksum="6D44CAB2DB10A2F7" modified="2024-05-29" version="1">MYHNLTLPHTGFATDDHFIQQNQLNHDAINLLSQIHIDSLINFQSTVSSASNSFSIPNQFSYSNEVTSTSPNADSIYPSTQLLQHHEFTSQVNTTVDDTSDNNNNFDSEFSNPTLAPQFLTTECESTHNQQQQNAINFFESNNNYQLDLKNPPSSKIFPISPMNSLYSPLSEPNQSPLISFTSPNLSNYNFENSNHILFNTSILPTSSPQISSSQISSPQVPNPQISSPQIPNSQVSSPQISKNSPPITPLLTPLLIPSSPNIQLDNQFSQSVANNFLILKGNKISKNDTLHKCPCGKSFKKIHSLELHSKLHQKDRAYGCDVCFLRFMRPNDLKRHKITHIEGYKPFQCSNCLLNFTRQDAMQRHVHSKRCHVPKNTFKSIEEAKDSKVEFKFALITTKNVPELEDLNNIIQHFQDSFVILLQNGLGIEDHVQLKFPNLKLASAVLYLGISQPEHGIIKFVDKSIQGFVLGLNTGTHFSNRHDADECINLLKEFYNMAKESGIQGLKYIEHKNLLQPNFEYQAVRWHKTQWNAAFGCLTILTGLDTLTLIEDDGTKSILSTVMSEVSETAKAVLKSNTPFPPVGKFDILEYLEASKGLGKYYPSIQVDYEKKVPFELEVIVGAVIREAEKSNIMVPILKTFFQMLKVVQKTRISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ42</accession>
    <name>A0AAD5XZ42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="13">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CNA1_2</name>
        <name evidence="16" type="ORF">HK099_005176</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPP phosphatase family. PP-2B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000393">
        <property type="protein sequence ID" value="KAJ3218162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ42"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033192">
        <property type="term" value="F:calmodulin-dependent protein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097720">
        <property type="term" value="P:calcineurin-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07416">
        <property type="entry name" value="MPP_PP2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041751">
        <property type="entry name" value="MPP_PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043360">
        <property type="entry name" value="PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45673">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="15">
        <location>
            <begin position="186"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="500"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3218162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="523" mass="59628" checksum="5AF5B5BD5E54CBD1" modified="2024-05-29" version="1">MADKKQSRPGSSKHEAHAALASAQSKSPTSGLPTIDFTIHTLETGETVSTRERVIKEIEPPAVLKPTNEQFYSKKDPTKPDLDFLKNHFLHEGRLTEEQALFIINKGCEILKKEPTMLEIEAPITVCGDVHGQFFDLMKLFEVGGSPADTRYLFLGDYVDRGYFSIECVLYLWSLKIWYPDSLFLLRGNHECRHLTDYFTFKLECKHKYSEVIYEACLESFCALPLACLMNKQFLCIHGGLSPDLVQLDDLRNLNRFREPPTHGLMCDLLWADPLEDFGQERTNEMFIHNHVRGCSFFFSYHAACAFLERNNLLSIIRAHEAQDAGYRMYRKTKTTGFPSVITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCTPHSYWLPNFMDVFTWSLPFVGEKITDMLLAILNTCSKEELVDDDAEEDEKESEKDARRKMIKNKIMAVGLMARTFQTLRKESESIVELKNVMGVDNLPAGTLALGAEGIKQAIVSFDIAKKADEDNERLPPPRVPGTEPTRSTHLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ67</accession>
    <name>A0AAD5XZ67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">METTL18</name>
        <name evidence="11" type="ORF">HK099_002651</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ67"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="313" mass="35832" checksum="261CAA41428A8DB6" modified="2024-05-29" version="1">MSFRFNFSVNEDEGESDATSEELEEVHSSNPAPKQIDPLKLDPIPISAELIHYSDHLTLLKRQVHDAKLEFCQNVELEDNNSNISKTITESTDLITGVYEGGLKTWECSLDLCAFLSELDFNFKDKTVLELGCGSALPGIFCLTKGSTVYFQDFNEEVITLITIPNLILNINFEKLMKEIDLKEAALETIVSPQEEEVLKSRRCRFFSGDWGSFESVLRSEEKNIKDFDIILTSETLYEKRNYKSLLTVMKNLTKKRNGFCLIAAKANYFGCSGSLKEFENLILRDEVFNWEVLKIFDGNNVRREIVKLSWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZF3</accession>
    <name>A0AAD5XZF3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000169">
        <property type="protein sequence ID" value="KAJ3222582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZF3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042195440" description="Serine aminopeptidase S33 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="92"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="301" mass="32960" checksum="E2E7EAD70D753E58" modified="2024-05-29" version="1">MQFSMNFFVVLLLQVVFSLSQQSLLDNYQRELDSPGSGFKGNNITEILRNRHIVLVDGIMNELASILNNYWADNIAALKEIGVGHTHLRYSSARGIPTNADSLYNDILVISKRVKLPIVLIGHSMGGAEAAYLFLKYPELLLDGVIEKVVCVNPAIGGSILADNLNLLGKAASLLLGSGLNSLKPVVAKKNFEDGFARFQKTIAEAGYKGGLTPSSRFEYLSKKLYYVRTALSPADISEFPNDRLLTAKDQMIQSNPAIGVDLGILEGDHIELVVNGFVSSGDVFHRKAFTRALLQKLFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZF7</accession>
    <name>A0AAD5XZF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Interferon-induced helicase C domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">IFIH1</name>
        <name evidence="4" type="ORF">HK099_005742</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000461">
        <property type="protein sequence ID" value="KAJ3216767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZF7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051363">
        <property type="entry name" value="RLR_Helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14074:SF16">
        <property type="entry name" value="ANTIVIRAL INNATE IMMUNE RESPONSE RECEPTOR RIG-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14074">
        <property type="entry name" value="HELICASE WITH DEATH DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="12"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="340"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="733" mass="84095" checksum="38610AD830F079A1" modified="2024-05-29" version="1">MTLKLRPYQSRLALTAQEKSCIIVLPTGCGKTLIACDVIKNVGKKTLFLVPSVMLVNQQSLVIRRETKLNVTTFSGGQRSVSNIFFDVLVTTPDALLNSQKRIPLLDIASFDLVVFDEVHHLIKKHPYRIIAQRIKEIGSNPKILGLTASLTYHTQTHKIPKMFSDICDDLSIDISEILTASNEELEKDNFFQIQTVKYDSNEYIIKKGIFWDVLQTNTSTYFLNKISENSPILHPITVAIYNSVKYLEDSYLKNKIANFTSPIQAENKLSYWLKYASELKTRHKTSKDADLKKKILFYCALLESLKFIVTTFQKNLELSLYFLFSEISNDNFEVEPFNLIKQEYELLKDDFEELSSLKSTLLNAYLTNENFFGILFAEQRISCHVINDFIAKDAELKDKLKSTFIYSTSAITGAALSPHLNISSTQFNERVNAFKSKKFNLLITTSVAEEGIDIKDTNVVIRFDTVQNPVSFKQSKGRARHVNSEFFVLKEEDKLKALIEAERYHDNFIQNLSNSLEQFEEDKTKSFFEENVEDEILIIDENFDFNFTKKEMEEFKYHTKNFFIQEISKVQRNDLQTLNVFIQNFIGYNLKELKCSFIDGNCEQEEIEEQESQEKALEEGEFHSNPVITGEIQNIPHQMMESTMPSSTSNLRNSINLRSSKDEVAIKISNLTSNSKLTSGSLVSLGLSKFNWTKFSTLVEKAALIALISEAETKTLKKAILHQGKKKKERKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZG8</accession>
    <name>A0AAD5XZG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000336">
        <property type="protein sequence ID" value="KAJ3219519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZG8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06786">
        <property type="entry name" value="cpPDZ1_ScNma111-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06719">
        <property type="entry name" value="PDZ2-4_Nma111p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025926">
        <property type="entry name" value="PDZ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366:SF8">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12812">
        <property type="entry name" value="PDZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ-like" evidence="2">
        <location>
            <begin position="323"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="945" mass="106019" checksum="86A4FE1DA20673D8" modified="2024-05-29" version="1">MESNIKKRKISSTLCDGKFDELNWENTIKNSLNSIVSIRFSQVRSFDTEVAGSSQATGFVIDKEKGFILTNRHVACAGPFTGDAVFHNHEETEVVPVYRDPVHDFGFLKFDPKKIKYMDVTEITMDPKKAKVGLEIKVVGNDAGEKLSILSGSISRLNRNAPDYGEMTYNDFNTFYLQAASSTSGGSSAATDYFFPLDRVTRAFKFIQNGQQVPRGTIQVHWLHKPFDECRRLGLADSTESKFRKLFPDEIGMLVCEVVLPNGPSFNLIEEGDILLSVENVEITKFVPLEEYLDSNVGKKICIKIERGGEIKEFTIKIQDLHSITPDRYIEYGGAILNKLSYQLARQYCVEVSGIYLAHVGGMMRLNGHNGNLILSVDSKPTPTLEKFVEAVCSIPNGERVPVSYCPIDDAHAISVSICKLDSYWSGLVLSIRNDKTGLWDIQDLTSKIPKRIPMKPLTATAQALNKNLGVGALKIFTSLVKVIFYMPIRLDGYPASKKAGSGLILDKDLGIVVVGRNVVPIEIGDVTISIFDSILIPAEVIFIHPTQNFTFLKFDSKLIGNTLLESCVFSEDVINQGHKLSLFGFNNNQRPICIETTVTDMTAICIPQNSNPRFRATNFVGMTLDTPLAQQCGSGVLIDKEGRVNGLWLTFLGERNANGNDTEYHLGIPISPVRTIFESFKDSYTKNGVFEKDFILRGFGIEVSPCMLSHARLMGLNEEWVDKVIESNPSQPRLFFISRVENSKVKSEKMELANGAEIKNEDNNLKELDLILSMNDKVASRITDFEPLTNVPEIIKFKILRNKKEKNIIFKSITLNELDRKVFLVWSGAVLQEPYRAVLQQFNKTKLPSLVYCSGKSKGSPAYQYGIGSTLFITAVDSKDCYYLEEFLDLVRNRKDGTYIRIKLISFDLIPVVVSIKIDKHYWPTIKFVKNAEAEHGWKKELID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZJ9</accession>
    <name>A0AAD5XZJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Multidrug resistance-associated protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ABCC12</name>
        <name evidence="13" type="ORF">HK099_004527</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000321">
        <property type="protein sequence ID" value="KAJ3219950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZJ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000610">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="125"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="372"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3219950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="619" mass="68514" checksum="7F67982E29EFB28D" modified="2024-05-29" version="1" fragment="single">ELAGKTRILVTHQLHFLPQVDYVIVMDRGEIREQGTYMELLELDGEFARLIGSYGGVEDNDSKAENSLDVIKNNLDENNRISGEVLKSDDADVAELMTKEDKAIGAVKQNVWMAFARNGGIWLSVVSCFILTIATATQVAKDLWLAFWTENRFPLIGQVGYVSTLVSIGILDSLINFVVGVIFTYICLNASRVFHDKALIKVLHAPVLFFDTTPMGRIINRFSKDIDGIDNTIFEKGMVTIKAYQKQENFIQVCDEFLDTTNSPLFLLTCGLNWLNFSLNTVSSLIVLSSVIVAVFARNTISPAIIGLAISNALQVTSYLSFCVEMFSNTEIAMNEVERIHYYGTKIVPEAPKEIENTKPPKSWPLLGKLTVENLDIRYSESLPLILNQVSFSVQDKEKIGIVGRTGSGKSTIINALFRIMEPAGGRIIIDGIDISTIGLNDLRTRIAIIPQDPVIFQGDFRSNLDPFGEHEDPALWTALERSNLKSKVIEIGKGLDGEVNEGGANLSVGHRQLLCLARALLRNPKIIVLDEATASVDYETDAVIQQCLREDFKDATILTIAHRLNTIIDYDKVLVLEKGRVIEFDSPKALLSNPNGLFTSLIEETGPANADLLKSLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZP4</accession>
    <name>A0AAD5XZP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004345</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000301">
        <property type="protein sequence ID" value="KAJ3220452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZP4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004868">
        <property type="entry name" value="DNA-dir_DNA_pol_B_mt/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33568">
        <property type="entry name" value="DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33568:SF3">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03175">
        <property type="entry name" value="DNA_pol_B_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B mitochondria/virus" evidence="9">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B mitochondria/virus" evidence="9">
        <location>
            <begin position="110"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B mitochondria/virus" evidence="9">
        <location>
            <begin position="153"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="336" mass="38680" checksum="9299D98D5B9CA137" modified="2024-05-29" version="1">MLLPNSLRDLCNSMQISYKKGFFPYTFPNASNLNYIGITPIDHFNQEDKIYVEIVNNWSLKNETIKYLHLDLMALYNILFKVSKSIYNKFYLNITSSVSLPSLAMKEGGYYGGLVDVYETFGENLFYYDVNSLYPFAMLKDMPVGNPVEPVRKSKLITPLGEWEAWYLSEELKAALNANVGYEIIEIIEGVQFERNSNIFKTYINDFYSIKVNSKGAERNLAKLFLNSLYGRMGIKPIDFETIFINKKDFNPNLSILSVMELDNHLLIDLPISYYKSKKPLVNIAIAGAITAYSRMHINKFKNIPNNKCYYTDTDSVILEKELSKDLISKKLGDMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y027</accession>
    <name>A0AAD5Y027_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">UBTD2</name>
        <name evidence="3" type="ORF">HK099_000351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000108">
        <property type="protein sequence ID" value="KAJ3224025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y027"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.225.20">
        <property type="entry name" value="Ub domain-containing protein, DC-UbP/UBTD2, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032752">
        <property type="entry name" value="DC-UbP/UBTD2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038169">
        <property type="entry name" value="DC-UbP/UBTD2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039869">
        <property type="entry name" value="UBTD1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13609">
        <property type="entry name" value="UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16455">
        <property type="entry name" value="UBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="171"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="247" mass="27307" checksum="95E0758C0C86F68B" modified="2024-05-29" version="1">MGNSSSRNRDRASGARREQRSGNRNSSAIRSSSQPPIVQTGEPKPLIPQKDIVWTHTNKITLEELTSMRQKACCEAISTLETAQAIIDASNIICPSGNLVDGCYDEFGNHYVIPQFCISEPTNLAKHRSGLEERKREETLVHSTAALTMLNPTAKKGVDDNDSNNLITGCVPITARLSTGKDLKITVDPDNNILSIRKQLLDNSEFKDNKKVNLKLIHFGRILDDNIKIKNTKISAGSVIQIMVQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0C9</accession>
    <name>A0AAD5Y0C9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ras GTPase-activating protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008159</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000087">
        <property type="protein sequence ID" value="KAJ3224614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0C9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF60">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN RASKOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="137"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="336"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="5">
        <location>
            <begin position="521"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="936"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1075"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="971"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1145" mass="128484" checksum="29BE3DE41AF2E089" modified="2024-05-29" version="1">MDVSFQQFLDIIPIWEEGDAVKVIKEKNLDLKLSQFINDNKISSEKTEKTTKSQETVKNGVLEEKIRKTEGDRLKLMKSTIESILLIEKINLESELCLNSISVEKASCIEVEKDVDVLTKSSSESSGVLLSSLSKNEKIISGKVNLKKENSIVWINYYAVIHGSSLYLFETPSNNELSKEIVNLSNLEVHYIDESYFKKANCFQLIPKTPSPDSSLRKSGKLLIDSSYYMYVNDSAEREKWMSHLYKLCYCCSKCVTFHEFETPANELLKKQASFVDSVGGSFSDITELYTGKKNTSSSSPDLKQESTKNQPSNLVIPEVKNSTNSLLLSSNSNLFTNNATVADFSQKVYPKRFLTIWITDGKELLSLIGSRYLKTCSFYCEILIDDIKQAKSNIVSGGENQTFFWGEEYKLSKLLPCYEKVKVILFGAKNSNDSYREIGYVNLPLDSFKPGKKVEEWFSVENKSASQNSSSQQQTASIRIGIMLSVEQRLPPQLHHQLLEILTEPTFACVRHLDEFLGNTREDFTKHFVNILISQKADLEGIKTLIGFEIDNAENSKILFRGNSIATKSLDQYMKQIGSEYLHTTLHAIIELLFKTTENHEIDINKLSPKLKPEEKLKQIKKNLKSLLDNADCLSYAIFKSVDKFPREFASIFHFIKNKVKEKWPDGNTQYTAISGFIFLRFFCPAVLSPKLFKLMPEHANESTNRMLTLLAKILQNLANLTYFKESGKEEHMLPCDVFIGDNINKSEEATTRGSLTETSPKDIKHNTAVVAFLFTRHLPELKKKRKQTDCPQLNLLIPLLNELELHSFEKDSQSYIKKSTSYYFNSTSVEEAMAITPEVNNSFGSSSKTKFSMFQKQPSITTPNGSSIGVIDESKSSFDKKGSSFAPSASFILNANEDLNSSFEDFSNTTKRMKSNKSVKKIFQQMKSLPELNVEKEKNVSKSELSNLEGANADNSTVEDEKLSRKNTTKFNSSEVSNSEPEFAGEATHVNSPKSKKGMTFFKNLFSHSSTESKVEGTIATNEGIPSAEKLSAKNLFSKNTTVKVKPEETTPNVILGKNTIKIGTAESYLIENQEKDKTPTSESGGGSNNSSYLGRRGSGNGTALKSEKSKLKTGIMGMSLPAEHAMMGKEEVFASLSGINEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1H0</accession>
    <name>A0AAD5Y1H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003518</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1H0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="166" mass="18881" checksum="025B603EFADD3798" modified="2024-05-29" version="1">MEVDTSCSICFDEYEVGASLRELNCKHVFHKDCIDGWLVQSGHRTCPLCVQAAIRKEDEDVDGGYLEMYFVMFPYFILMSILILWIVYLSSSPKVVEFLRAKGLSPTELERLRTFHFTGNEVGVMESENSSNVTNQFQPPLKDDVNEQCTIELDKVAPSEETGLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1J7</accession>
    <name>A0AAD5Y1J7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002939</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1J7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF0">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="587"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="625"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="666" mass="72038" checksum="D54BDF25C101E181" modified="2024-05-29" version="1" fragment="single">IGITQGATLFATMLGGLVMKPYLAVISHFNKTYKFMGPKQHCCFQSAATASGALNGGLTAGVIGLFWMQNDSEQLTPAQRLGGFKGLAGDNVLGLFLLVFCAVGFGVFMAVPYRKIFIINQNLQFPDGLAAAEIIHSMYKKGRTAAQDAIQARKIKIMITSFCVGLLLYLVQQFFPALIAWDIFKNLSNCGVQQSADDCIANPPQIEGENGLVATKTFIPFALAAAWGWKLSFDPVLVGTAFIVPHHVNVWFFIGGVLAFGVIGPLGVYNKEYPAGLSYGGAISYVNKHTLLWPAIFVVLFAAFFNIILEYQALNGILSGFKGNEDATEKKSFLDKSRQDIKAMFSKKEPGTDRSDEQTPFLVWFGGFIVLAAITIGIEATYFGPGNFEVEWWHVVVSILSCIVLAVVYLQILGKTNWGIISVMGKTAVMILGVSGAPVGATLTMGNLVAQTMSQVGDLTQCYKTGHLIKASPQAQFVANVIGSVIGLFSAVGGFLLFTTATPCILEYPQTSHCEFLVPSTKAWYNLAIAFNGGFKVGLEKNSTMSPTGFKLCVIFCVLAFITNVAKKSLQVKNPVAYKRWNGFFPMYEVMFIPFILTADLAVATFVGTIIKFSWQMANKKAEKIYGVSLGAGLMTGGAMGGVLYCIMKISGVGKYDYLQWGGQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1U4</accession>
    <name>A0AAD5Y1U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">OTUB1</name>
        <name evidence="10" type="ORF">HK099_008664</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000098">
        <property type="protein sequence ID" value="KAJ3224273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1U4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22749">
        <property type="entry name" value="Otubain_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.60">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.20">
        <property type="entry name" value="Peptidase C65 Otubain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019400">
        <property type="entry name" value="Peptidase_C65_otubain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042468">
        <property type="entry name" value="Peptidase_C65_otubain_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042467">
        <property type="entry name" value="Peptidase_C65_otubain_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931:SF15">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTUBAIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12931">
        <property type="entry name" value="UBIQUITIN THIOLESTERASE PROTEIN OTUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10275">
        <property type="entry name" value="Peptidase_C65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="9">
        <location>
            <begin position="69"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="278" mass="32011" checksum="F7C257A029BBC279" modified="2024-05-29" version="1">MTELTKLNESEAVIGPGERDRPSDEEILKFEKEIKKAEQEKALISQKMDFTQLKLEYSKSGSNLTSQYSMMRTTRRDGNCFYRAVGFRFCEILKRELSDQNNSTSKFKPWATWAFNNVKESKNLLVKGGYDLIAVEDFYTMFIETLNKEPDQIFADFLTEYVSDTIVCYLKLVTAAYLKLNSEMFEMFILDSYPTLEDFISSQVVPMNIEADNPQIVALVNALGLNVKIANLDTSLTQNGEENYHDFSPFESVVDNIPTVTLLFRPGHYDILYPNYEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSP1</accession>
    <name>A0AAD5TSP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">54S ribosomal protein L17 mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">MRPL17</name>
        <name evidence="1" type="ORF">HK099_003375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002210">
        <property type="protein sequence ID" value="KAJ3199009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSP1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040008">
        <property type="entry name" value="Ribosomal_mL46"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="104" mass="12384" checksum="6D31937622081A92" modified="2024-05-29" version="1" fragment="single">MDKVLYLLIREKAEDKFRLPEGSINDGELLHEAVKRELNEKFGNGFESWVVGKIPVGHINENQKNIFFYNVRIFFGQVKFKKENFCWLSKDEIKDFTDENYFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT73</accession>
    <name>A0AAD5TT73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001721">
        <property type="protein sequence ID" value="KAJ3201474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT73"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43802">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43802:SF1">
        <property type="entry name" value="IP11341P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="22905" checksum="883FB360BE7799C1" modified="2024-05-29" version="1" fragment="single">QLVAVLTGANGCFCAGADLSAVVKIKEKESKANLLSSNMEDMGPMGPTRLFLSKPVIAAIEGFCVAGGLELAAWCDLRISKPSSTFGVFCRLRGVPLIDGGTVRLPKLIGRSRALDLILTGRSLSGTEAFNWGLVNRLVPENEDVLTFTINFIKNEILPHPQLCLQMDRKSIFDEEEEKKLLAIEFKNGLKSLNDQNFGTEIKKFFSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTE4</accession>
    <name>A0AAD5TTE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Intraflagellar transport protein 56</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TTC26_1</name>
        <name evidence="7" type="ORF">HK099_001976</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFT56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001614">
        <property type="protein sequence ID" value="KAJ3202153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTE4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120170">
        <property type="term" value="F:intraciliary transport particle B binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035720">
        <property type="term" value="P:intraciliary anterograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030511">
        <property type="entry name" value="TTC26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14781">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14781:SF0">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3202153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="78" mass="8722" checksum="B820FF227CC88D10" modified="2024-05-29" version="1" fragment="single">MLSRAKPAVNPNQPQNAAITADKKKSTPKVDTFINNRDYTGAVTLLEFLKTTGKFDNDTLLWLGYSAFHLGDYKKAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTI4</accession>
    <name>A0AAD5TTI4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001586">
        <property type="protein sequence ID" value="KAJ3202334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTI4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="10671" checksum="2EB4F190800181DF" modified="2024-05-29" version="1" fragment="single">IFETIVPSSSQSTLSEPNTPPPSQLHYEPQQQIPQQQNNTQIQLIQPTYLNPTSFGGNLQEVASKSLKKSETRGGGKSFLCTVCNASFSRKYDLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU45</accession>
    <name>A0AAD5TU45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001502">
        <property type="protein sequence ID" value="KAJ3202915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU45"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="72" mass="8428" checksum="63A88A274E1C980E" modified="2024-05-29" version="1" fragment="single">EELQKAALYGLTLLNENNALRNENLKLKTTLEENKILITNLTTDFEDLQVKLKKFQNENVTLFEVSNKKKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUI8</accession>
    <name>A0AAD5TUI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001220">
        <property type="protein sequence ID" value="KAJ3205263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUI8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="744" mass="86550" checksum="4E92C02C3B4EDF26" modified="2024-05-29" version="1">MKEVRNFNPCVNCKSKKKKCSNGNPCERCSKANVECIYPPVRDINSTVKLKNSVPNTSRLYIKNFINNENSPPSDTPTTFFHLDSMFPLLISQVEIAIKQDKPFVLKEVNRQEKLQNLAEVLNLYNESGKERCFKLKLISYLENTLNNKENRTLTTTPVLFHNTSFNLTNKNYSAPRLVKHKNSPSSIADFNNIMNMFNFSGVFNDPICDPISSHSFIKEIDSEEAIQVYMPTEGIIQPSQNLNNALNLLLTKKYYTQIKNLSKVDDVVLVLAAMFYISRIRCPSYIFLLTPDSDNKYKGSPPKGQPRLPNETMRQYLRRTSYDLSQLIHILNYMFHHDSFRFYFWLAYGCQSSNHPLLYETFGGPNVAALNFSEIGYSLMINIDKNLDIYIEGMLDYCHLQFSYGNRIKAIEAYDKLEMLGVLSDYDSPNGVNCLEFAKNPAMVYKKRILWVKFFCFSTFVKFPLIGDELQNMDLTLESEWEKFFVLESVPKFVDIGSFFTITDFSRICFLTRKIIRFANTKNLFGDKDYLLENTVSLHNELIGWFENLSKNSRIFQSLADYILGFKLAAPMHSREFYDVSSKSRLLIWFLYGIIKIHSIQRKNFPSYQFPFEKGGKLKGTSMEFILCGIRALSSILANLPPEHYLRKVEDTKRFVFHLDNIIYMTPILEEVVVISLECIEDNIEWASVFGIQEEVLNFHIQDFFIKILRGFNTPYALETFYRVEKKIKDILYQRALKNNYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUX8</accession>
    <name>A0AAD5TUX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">G2/mitotic-specific cyclin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CLB2_1</name>
        <name evidence="8" type="ORF">HK099_000502</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001115">
        <property type="protein sequence ID" value="KAJ3206555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUX8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000010">
        <property type="entry name" value="G1/S-specific cyclin Cln1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="106"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="201"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="209"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3206555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="349" mass="40429" checksum="34DBF2EC9C3049C0" modified="2024-05-29" version="1">MSYLQHHKPLAIKIPKHLSNTSISSNDQPHYQHSKHINQNINHVNYGAALKKIENSFQSIEFEEYGDEISSYMNDLEDKMQPLKNYMGIVQAEGQIDWKMRKTLVVWLVEVHKEYNLRLETLYLTINILDRYCSLAQVDRPTYQLLGITSLLLAAKYEENHGYVPSLKNLSYMCCDAYTDKQFRIFERRILNVVGFEMGFISPETFTKRFLYLNPFLFTNPETRALIRFFNELSLVTHNFLNFKPSVISLASMLLAHQITEGSGWVVEEDVEICRVALIQVIPEVPNAIYQKYNQVELCNVSSLAKNWSNQQRKMYVSRLYASGQLTPPKDNAGFTFPNSYNAGSDTTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUZ1</accession>
    <name>A0AAD5TUZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001034">
        <property type="protein sequence ID" value="KAJ3207763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="13654" checksum="C7C18C487304802A" modified="2024-05-29" version="1">MFFIDKNGNSALRVSEQDYILGIADFTGELMRYCINMVGRHRNEEVNHSKALLQQISAVFGELDFTFLKRKTEELKRSLAKVEKVCYMVKVQQAEFPDINLNIDISNVKFEDDFPKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVD3</accession>
    <name>A0AAD5TVD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001575">
        <property type="protein sequence ID" value="KAJ3202409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVD3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="219" mass="25456" checksum="0A91DB4B63230B93" modified="2024-05-29" version="1" fragment="single">MEILKKAVYFQLCFGFPYVVNVDSDARLFEYAFGILLEQRLKNSVERNIVVNESFILQTAYNILSKENDILRITAETRIGESLIAQSRGCLWEDYFPHHLKRIAENRNILDILTEPTNISSNIYNINEFPIISDLCFFIERCDGGGLIPVFIQLKLSHHVSRVAALSTTDPIKFYSDKNNKQIENYIEEDSDGWVRYEKVFDGTLENRIFDETHLIYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVN9</accession>
    <name>A0AAD5TVN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001037">
        <property type="protein sequence ID" value="KAJ3207714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVN9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="319" mass="36822" checksum="268660E042A62836" modified="2024-05-29" version="1">MHFTSPEFNHQTTKEIYALGLRFFTLLYADAYKCTAFLVESRNLLIDSINFYQKRIKVSNKTLPKDFDISTLKNCYFGIFENGLNCPACALYWDKNDVNKNLHSYREHFTKKDHGELLITKLQDPENFTERRLLNLLCSCAHSFFVFFTNHTGKGKAKIAPYGFMEKAVPFVAFSESKFFKSVQLNGKIEENELLEINKDCDFLEGKVDNNTLDERGGGQEKILNKADMLMDALLKLRSNCIPVPPLETILPRLLSNWKVIQKQKGPAKEFFQNAQNFKNIQDLYNTVDNYFVDEDLNGELTNKGIIKDYGSQWNLALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVQ6</accession>
    <name>A0AAD5TVQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_000166</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001022">
        <property type="protein sequence ID" value="KAJ3207931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVQ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12339">
        <property type="entry name" value="RRM2_SRSF1_4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000028">
        <property type="entry name" value="Putative serine/arginine-rich splicing factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF51">
        <property type="entry name" value="SERINE-ARGININE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="107"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="171"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="180"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3207931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="271" mass="31916" checksum="6B52C0D5760F83EE" modified="2024-05-29" version="1">MSRIYIGRLSRDAQVEDVEKLCAKFGEIKEVNLKNGFGFVEYYSNRNAEDATDELNSTEFFGEKIIVELAKGLARRRDDRRSDRRDDYRRSERESRSSRRAYQHGGYRLIVDNLHSSISWQDLKDYMRKAGHVTFADAHKTRVGEGVVEFSNKDDMRYALETLDGTELKGHKIYLTEKSPRHHSRSPRSRSRSPRRKSRSWSRSKSRSPRRRRYSRSRSRSPRRRSYSPHRRSPSPHQLPRRSAEGRSYSKSPVKDNVGDNEKKFESDKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVY7</accession>
    <name>A0AAD5TVY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000806">
        <property type="protein sequence ID" value="KAJ3211921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVY7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021463">
        <property type="entry name" value="Methyltransf_34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11312">
        <property type="entry name" value="Methyltransf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="305" mass="35603" checksum="2274588C88786281" modified="2024-05-29" version="1">MKKKNFNIFNEINVLDIFKESCEEELTDENFQEKLKQIKKFFIERDYLGIFNDKDLIKVYATSYSPSRALCWRNLFLNNEHLLKVITEKSCNCYLLGAGSGSELIGITAAYSEHLKVLKNESTDVDHLENVKTLSLNVQDLSDNRILLGKMEVSLRSKYSKVINDNNFKVEYSLGDILSQEIPNLQYLKSILENANLITAFFLLNELLSNSKLNFTKFIIFLVKHMKRGSHFLVVDSAGNFSDVQIGNVDAANKKKYMVYQLLDGIKDFEILTRCDSEWYRFPKELQFPLKLDNMRYFIRLYRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWR3</accession>
    <name>A0AAD5TWR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000999</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001257">
        <property type="protein sequence ID" value="KAJ3204863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1066" mass="120350" checksum="12C13BC3B3B9C995" modified="2024-05-29" version="1" fragment="single">LMGTLSQIKTLIKTLNNKEKVKYNQKLQFICAAVQALEKTGFQNSFSPEATPFQKDLKIEKEFFELFNKEPDFVNKFCLDEHEVNTTFNSMKNLLLRKITGFMVLIISLFGEKLNLNFKLKGKLNNLILDTVFGQKHVQLDFKAAPLKNSPSSFPPVSSGWEDMDVDNFNDESNPMVQDGWDVDLGFDFEDELDTKPYGILDPIKTDAPAAEGWDLESNFEFSPSTLEEINFEVKIEDSLTESKIGSPFDDEKNPQTLKNDFENEVNVNSSHFNASNSFINFEDKVDKNITSVKKNVEVILSSQLPTSIATINMQVELENTENTGWDLGSEFGSFSPTTTDFKVTENLDVGLESLNVPGNFHNEEPFEHKKELGWDVESDIEPISPIKENLVEDDTIHIENNSSIVGGPVFSVPSIGKTDYLSSELWKPLKEVEDFDREKDIENVKLQNQLNSVTTDRPEIYDISWNKQPADGLEFSPHHFKQNNDLITGPMESDASNIAENSNLKQVSISPQNESTVVGLEYSPTNVLELPYFGNTADNANVAQSDVTKSVLTIETESEKNNENNLSISPKNENIIKEELTPAFSDFSKTGKKLELIANEMSPSNNEITDSEPSDFKTTPTSIHSANLLMNVLPTAIEETGWSFEENSLLSLNIENPNTTENTKIIESDIYKQSTPDDATPTEAITSNIIPVNHNLDLAEENFKREDEIAYNPKTIEPRNTEPTGWDFESGDEAFFTEHIQPDIITHYGEKISVDSNEQTEDISSNLILTVNQSNWNFEDNFFTNTNTEANLKNPAKKVDKILANNPSIPVSDKKSQHIFFEDNFDGKLESGNKLSSSNPKAISEDSNLIDIPDLPNSIQSPFSTEFQGGGTISSKNKKNSLLSKKDVNQLETSIPTEDREFFFKTENFSEDCEERKQLKLQLEFFFDKISEFKNKRSSLLKFSDVLGGNVNYDSGTSLYSYNNLMLQVFKEVITESNDIAAKDVFYRVPPKKKKDTFGVNVFNRLLSVEPLHPSQFQTILFFVVGGGLKFSELKLMNDFLNLKEENLHLYDNVERQKSNIMFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWZ8</accession>
    <name>A0AAD5TWZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Blue (type 1) copper domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001228</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001324">
        <property type="protein sequence ID" value="KAJ3204228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWZ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028871">
        <property type="entry name" value="BlueCu_1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00196">
        <property type="entry name" value="COPPER_BLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Blue (type 1) copper" evidence="5">
        <location>
            <begin position="13"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3204228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="139" mass="14914" checksum="CAA87A62E8DBCD90" modified="2024-05-29" version="1">MSKIIQVEVTDDIFTPATVNILAGDTVQWNFRSFHNVYETVDSSCTVKNTWNSADLSTGTYTQTFANNGTFYYACTVGNHCQMGMKGVVNVGALSSATANNSPATTTSTTTTSISKSNGSKFVVLSTAFYILSSTILFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXN0</accession>
    <name>A0AAD5TXN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000629">
        <property type="protein sequence ID" value="KAJ3214347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXN0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="733" mass="83392" checksum="77694DB5E0AA372B" modified="2024-05-29" version="1">MSNSEVWFQLVDSEGNPYNHLKSTTVIVGPDTDVDDLKSLIKEELSNNLSHVDAGQLKIYESVDKLSENPINESTLVLKLDNSVDLVVVVPDRVTDERQVDERSGQENFKKKMRVSESEFTIGNNGSSQLLGKPPLTSLSTDILDFDTVTKQLNLLFSKCKFDAIISYMEKTETKVDSCNKPSLLIDELGRFRSSALKPLKEKILNNEVIVLLGTSGCGKTRTIFEYLATDYGFFFTIKGSSNDSMPGSSDFKEFLKKMEIKLKRKRAVSQPRDEAQVIVDVGENSFPSKTNNTSALLNAIKNAVIGLSDDFVFIASGTGLRLNDLSGNGSKFSAACKINPAELKLVVSNMWTTTESINGYIKHYLKETLSEENCILLLGRVRVVATFIEKFLTSNNKNTSVDEYFDIFYKMLTTCEDIEWSFLSLFNRKRFLEEKHYLQVMENLKKAVYLKLCFGITYTVPVVQEVLLFELAFGILTEDSDEKDQLTISIKENLMLQTALNYFSDCNPKFLQSFAERRIGDNRTPQSRGFLWEEDMPHHLKEVGEFKSLWKIFTGEDFDSTIHNLEKETLIQKDGKKSLSDFLKNPESTFFLPNCYAGPDLCFFISRANKKLVPVFVQLKLASDLNLQNALATTNPAHFYRNKNLKTYGRYMYEKGECLRIIEGDYDNTTIGVVFCYQKCLRTPICTKMEKDGVVRYEKVFDELNVDEFFTAEHVEYLNTITNVLKLNATNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXY8</accession>
    <name>A0AAD5TXY8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-processing factor 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CDC40</name>
        <name evidence="11" type="ORF">HK099_006433</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000554">
        <property type="protein sequence ID" value="KAJ3215294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXY8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000034">
        <property type="entry name" value="Pre-mRNA-processing factor 17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="277"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="321"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="407"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="508"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3215294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="569" mass="64577" checksum="FB1115C2D502773D" modified="2024-05-29" version="1">MTTLVSNYVSSSEDELQENSHINDTIARHANKRQKVNLNPEIQTTVNDLIDLVPTSKEITTNLNYNQLNKQVQGPINPFSTNRSSTKNTLTGFVEEAAISDFQFQSLQRTFKRDGYTLNPDGMGYVGDINKAILNEGSTIAEEKQNKTKKQKRLPKGDSSKVDGYFGPWAGYENENVGKQVVEGEINKSEEAVKVADDVKLPVVENIGEEEKEPEVIDPEDEELKKNTFEKTIFHGKSELDYLGRSYLHVPTDLDIDLKSTPGDKECFLPKKVIHTWTGHTKGVNAINFFPNSGHLLLSGSMDNSVKLWDAHHDRKLLRTFLGHTKAVKDINFNFNGTSFVSAGYDKWIKNWDTETGQCINRMRTKRLPYCVKFNPDFQRANTFLVGCADKCVYQFDIRSNKVVQTYNQHMGAINTITFVDNNRRFVTTSDDKTIRAWEFGIPVVIKYIAEADMHSMPAVSRSYNKKWLACQSLDNQILIYSATDKFKYNRNKVFKGHLIAGYACKPSFSPDDRFLCSGDSEGKVWFWDFKTCKVLKKLKGHEGVVIGSEWNPQEQSKVATCGWDGTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYD4</accession>
    <name>A0AAD5TYD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000535">
        <property type="protein sequence ID" value="KAJ3215563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYD4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018810">
        <property type="entry name" value="UPF0662"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086:SF1">
        <property type="entry name" value="CU(2+) SUPPRESSING AND BLEOMYCIN SENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086">
        <property type="entry name" value="UPF0662 PROTEIN YPL260W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10303">
        <property type="entry name" value="DUF2408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="470" mass="53868" checksum="2C0ADC8521298455" modified="2024-05-29" version="1">MTRREKSTRNEAVMPVLMNLQHDLRNKHKEKAPKLTEIQDLAERTWKANFMYENRLAKLEKEKRMLENTMKNVWEGFDKLILPMWRIDDDLVPVYENLVEIKRSLEALDCQPFYNADDSERLLKLQEQLHNIENEHCVNGLYVPIGWKRNERIPSGQSILASLMARNYKLVRHIQERGPTVSSELIPLESRLRRIIQTLDMIKENYTAPYEDDFGPIPIEPLEIRLLQDQLAEIEGMKENGMFYAEDGSIPSGQAVLHSLLEEAYDLVHDCLIQIENQRAGNKEVDLVEIALSKARYVSDSIVTQASAVTKDIAAGARSVSLSSLHALQASLDEGSYYLRKVIENPSDSVKSTSRVLASTTRAALGFLSKLYGEFEPVDPSLLDTYNQILKTRNDLKLLRNEFDLNKIRNEVLDTVNLNKRLRILQEELDAIDRQKVDGKFVNKDGEIPRGQALLSSILDESYCLVAEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYI5</accession>
    <name>A0AAD5TYI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000479">
        <property type="protein sequence ID" value="KAJ3216437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYI5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="458" mass="52552" checksum="AAA7DC8A2495BE47" modified="2024-05-29" version="1">MDQILQTPRIKFLTFAPRNGFYIRFKDIDGLDFHKTASLPASLHNKLSSRQIHLPPVSFLNMSESNGQEIWFIRFNDGSTTWSSGVQMYSEKLWEAITNVDFGEMMEEDDDAVSYCVFAPNNGWFLQFRNGECCFERLPKSLNQLLEEKGIVDCQTDPETAKKRLIDRALWKKLKQTGSLNSNNTQNEFNHEARRLSNWRSFSSNSRRPSIASMDALDNTQSNFVTVESMSIGANGSWFVLFDDGEFLFEDLPTSLDICLNLNLEEADPLQFDVFLSPSDPSAYVVSFEDGSIQYSVPEEMLEELNQLKIHEFESKLKKKEDELGDLFTSFQPDIICEEGNEEIEISEVSLIEAQDSFSQLEISQQDSGIDLDVTNSCKNNQNVNLATKVESTEEIHYLSYEEVYFTTRSINSTLPSEICENSESNIYFLYTDIMRGVKSNENLKPIHVFVDNKDRVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYR7</accession>
    <name>A0AAD5TYR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoglycerate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007403</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000713">
        <property type="protein sequence ID" value="KAJ3213413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYR7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050857">
        <property type="entry name" value="D-2-hydroxyacid_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42789:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="33"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="145"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3213413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="46116" checksum="3347526DE1E586B8" modified="2024-05-29" version="1" fragment="single">MIHNHQYQKTGIFEKVKKDTICLEMVENKKLLLLDPITLSAEKSLELAGFKIDRNYDFLTEPQLLKKVSEYHVVVVANERNEIYLTDEVLRSAHKLLAIGVFSRFSNQIDYKTAQSMGIPIFKAPYQHQHSIAELVKLKKIFLTEDIHSGFWRKVSDGCHEVRGKVLGLVGYGQIGSQLGVMAEALSMRVIFYDDVSLMPIGRAEEKSLNEVLSTSDFVTVNVSDRKDNIKFIGRNELNLMKKGSYILNASFSEAIDLVALAEALESKHLNGAALDSFSDDIVNGTWPNDIIARLAKQDNVILTPQIGALTTDAAERISNEVSHSLIRYLHDGSTVGSINFPTIVTWPLKDGTRRILNIHRNVRGVLKEIDSILSSYNVGKQVLDTHDGYGYLIADIATDSVTTEIVSQLALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYX8</accession>
    <name>A0AAD5TYX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur clusters transporter atm1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ATM1_1</name>
        <name evidence="2" type="ORF">HK099_005396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000417">
        <property type="protein sequence ID" value="KAJ3217637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYX8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="15810" checksum="10E21925AFC29885" modified="2024-05-29" version="1" fragment="single">FYDALSGKIEIDDQDLKTVTQYSFRKEIGGMRLSGGEKQRVAIARTMLKAPSIILLDEATSALDNTTERQIQQTLKTLSKDRTTIVIAHRLSTIVDADLILVVKGLLFFLLLIKCFADGRIVERGTHNELTAKGEQGNFSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYZ1</accession>
    <name>A0AAD5TYZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HGH1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006382</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HGH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000545">
        <property type="protein sequence ID" value="KAJ3215414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039717">
        <property type="entry name" value="Hgh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007206">
        <property type="entry name" value="Protein_HGH1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007205">
        <property type="entry name" value="Protein_HGH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387:SF9">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04063">
        <property type="entry name" value="DUF383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04064">
        <property type="entry name" value="DUF384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein HGH1 N-terminal" evidence="3">
        <location>
            <begin position="91"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HGH1 C-terminal" evidence="4">
        <location>
            <begin position="292"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="374" mass="42405" checksum="EF29AAA0EEA4A1C7" modified="2024-05-29" version="1">MDEILTYLDNDREEVRLLAAENIASLSASPEMLDFFKKDNFAAVQNLMQLINDEVMVAHQILNSLINLTAHIEICEVMNIDSFIYELILKIVLPKCLLSDPCCMLLNNLTKSPAIISKLLPNSENKENIGETQAPSKLGYRHLDNLLEIFCKGDGINGTKKYNPHANYHFLSGVFANISATPGGAEFLLGKSTVDDSQRLSRLIVFTTHKDKIRRSGVISVIKNTSFLIEKELKLFKPVEDGGINLLGHILIPLAGTEEYDDEITEKFLPELQYYEGTRESDAVLRQFLVEALLIMCSTLEGRELLRDKGVYYILQKLHLWEKSESVQEVIEKTVDLLQRDEDICQITEKVKISKIVEVVDSDDEEEEEINKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ71</accession>
    <name>A0AAD5TZ71_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000853">
        <property type="protein sequence ID" value="KAJ3211150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ71"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="140" mass="16390" checksum="4E4873FD9BC5ACAC" modified="2024-05-29" version="1">MCCNMIGKLRIGLIISELSFLKVLSKIRASSLRYIPQFILLFWLAFRCYDQGFVDWLNSYKFPLEGKIRIPFLERGLPGVEYKFTLDEFVTGLSILLVVEISPIFQRLFQLRIFQLLGKASFGWYVLHCCKFLPIILEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ80</accession>
    <name>A0AAD5TZ80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000420">
        <property type="protein sequence ID" value="KAJ3217592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ80"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="327" mass="38622" checksum="3371F1F7CE6A39E4" modified="2024-05-29" version="1">MYKIEAKNILVFKPFGIENQNEIPTQKVKRKNSNSYLNDIEYVNNFSFPITEGTLKNITLESESVPTKLTLHTAVWGYSDVVNKRNKKMHANVIFGRNFIIRIDESNFKLQSFQYSISERQNNDISQFQHSIHYLHNYLEFDDTIYSSARWELLKSLFVLSNIKTEILDNLKYDPILLDYLSCKKKLLAETFLPLLEVLQHTVDISTSNDENKIALNYENNSLWKIGEDLDRIHQKLMRECLDYFESIRGSEIFLNITGYKNEEGTVEEKYRHIIYYMLPLLKPKKRKEFTPADFSNENLKLTNQEEFFDFIDKDFKEGAKENISLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZB7</accession>
    <name>A0AAD5TZB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000534</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001122">
        <property type="protein sequence ID" value="KAJ3206470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZB7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="591"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="367"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="753"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3206470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="773" mass="86894" checksum="B966E8F314CD57D8" modified="2024-05-29" version="1">MEKSINDTLKNTIIDANIQMEYYDSELTPYKAVMHGFDMITSEKRETSPLLGLYGEFISARTIPLALVSSGYNILQCSGMATSPTLTDKNHYGTFFRTVPSDIFQGTALANFAFAHNWNKVAILNENGAYGQGVRATTFENEIDLIKKSFARIIIIIVYPDDLLKFMRRARIDGLLNSNYVFLGSDSTSAISSILQETSDMENFEGYIAISALDRVVEGNAYKSLNSEYQKIFNQTVPGYGGFVYDCIASLIYTFENFLISTNSTPSDYTTKFNSSSRVSLQNVQKIAFTGISGNVSIDENGEPKNQLYTVTNVVNKMKTSRVAGTVEGGNAKIIYNKKYDLVFNGGSTVVPSDSAGEYEVKLDNAGTIVVFAYFMLNLLITLGSIIFLIIKRKENTLKTLSVPFLFLISLGLLLNWLSIFSFLGKMTVQTCYLQQVLWLAFCLIFSSLLVKVFRIWRVFDHSGVHSVYLTDTKLFIAVSLLFIGEILILVAWAVVNPPVPTIVNQQEYFYVECLSDNLALQTNFNLVLIVYNGLILCVVMYLAYKTRNVSSAYKESSWITQLSLNVLLCASIPILLLFTSNDNSILNKFYIKMLTLAFGTSVTYFCLIGRVILSLVIIQSSKKIRQNRKQKFKQTTSIIKSAISSTNKVIKESLILKKFTVMSKNEKIWFSNWKNTQITINEITCNLHYLKHDFMPNPDGISISMRSLKFEDMGFDTLRIFTAKLSFIILCSEEGEKNRIISCLRKVKEKDHDPEVPNDAVKGGNTAHQGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZZ6</accession>
    <name>A0AAD5TZZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004811</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat IPI3/WDR18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000351">
        <property type="protein sequence ID" value="KAJ3219117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZZ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120330">
        <property type="term" value="C:rixosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045227">
        <property type="entry name" value="WDR18/Ipi3/RID3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763">
        <property type="entry name" value="WD-REPEAT PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="112"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="161"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="272"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3219117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="51971" checksum="CC10AAA1394F88BD" modified="2024-05-29" version="1">MEENILVSTNEGIQIFSLSNFAKKNTLKNTTKIDLALVQNFKNNAILQEKNKTTITNLNLKNNSGQSLIQFNSSEIITSYSLSKNEKFLVGGGLSGRIYFWDFKSGFLINSFDGHFKKINNLSFTSDGNFFCSCSDDGLCHLWFLTDIFDLSASPAPFKTFQGHSLPVTDFYLGIGLFQHARLFTVSKDRTLRIWSLSTGNLLTTILYPRILTKLVVDPTENHLFVGCIDGKIFQLDLFKKFKDTEIIYSVINNYNAAHLEKVEDFDENRVMIGHSQEVTGMSFSFDSTKLCSSSLDGQLIIWDCQSRQILKVLISQDSPIKFCQIFISFKDENIDKLHNHNLNFNPLKKFIEVDEREKSKLILDLEEDYFVDDQMLLELETEYSCFEVDHDSTTITGYNNASKYFAKDESFFKNELNVALEKLENTIKIKEKLEHCNKEILKICQNEFMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U067</accession>
    <name>A0AAD5U067_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000354">
        <property type="protein sequence ID" value="KAJ3219054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U067"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="entry name" value="paralog of FGE (formylglycine-generating enzyme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017805">
        <property type="entry name" value="SAM_MeTrfase_EasF-type_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03439">
        <property type="entry name" value="methyl_EasF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF1">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="4">
        <location>
            <begin position="48"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="3">
        <location>
            <begin position="540"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3219054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="791" mass="91213" checksum="262E646AF82E7D01" modified="2024-05-29" version="1" fragment="single">MKSTVNIIKLQATINATRDLIWNSLQKKSTVFDPKTSLNSDENQLLIRSIPTLVLYNDDGLDLFDQITYNHQYYLTDCEIDIFKNYGVQMAEYVQNDSIVVELGVGAMRKTRHFLNSVVEQNKSPTYYAIDLEEETLRSCLEELAKEFPTIKFVGLCGLYEKGLEYISKLPKANSPKIILWLGSSIGNMTRPEAVEFFKFVDKTALVPGDLFFVGIDRRNEPEVISKAYNDDMGITRDFILNGLSNVNDIFNENIFDKSQFEYVSIYNSILGRHEAYYKSLVDQTLSVNDPKFEDIHLCKGELINVEYSYKYNIDEVETLAHDSKFNHTHCWFDSTKKYGFHMFQRPPFFFPKVPTETLPTCPTLEEFHELWKAWDLVTGTMIENCYEKPISLRLPYIFYFGHIPAFSDQRLNQYLCKPLTEPAEFAVVFERGIDPDVTDGICRHSHSEELDTWPSVEDVLDYLSRVRESIGAVFKEFDNGKEFSSQLKEILFMLFEHEAMHLETLLYMILQSDNLIPPKNVLPPPFSLHSTNMKIPSSSLIDVDGGIEKVGQNKNRKVLGWDLESPIQELEVKAFKIQTRPVTIGEYFKFLKLKRKENAVSLEELIPSSWSYDPEAINSGMDLNPSDFKLKTVFGKLSLSAGWLKSVSCSYVQASAYAESVGMRIPNQQELLKLKRLSLEENGDFVTRGTNVGFSSWLPKDLNIKKIHNDIRDVDICGNGWEWSSSVWEKFEGYKTSDLYPGYSFDFLDGKHNLMFGGSWATHPRLALRNSFKNWFQRDYNFMFAQFRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0C8</accession>
    <name>A0AAD5U0C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000323">
        <property type="protein sequence ID" value="KAJ3219883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0C8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="699"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="790"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="699"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="723"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1256" mass="139543" checksum="0B550C303678CB9E" modified="2024-05-29" version="1">MSKFHSLFKNNDSNNFDDNFESDTDDLFTYSREALLEIFNNLTQTENKISKFPSVQLLKREPPLFNTPFTELEQKLFETGVNSEVKGYKKPYTGPKASRSYGAKNDYDRNAFRGKSEHSAGERYRRYEKKDDLWDSPNANSGTFSVDGSFNIQKENRPRKTRSTSPSKNRKQSKSPKRTQFEQTSQIEDLENHGLLNVKNQSHDFSRSEKFQPIITDENDFFPASAKNSNVKRTPSRSNTFPETVRSNSPGLMGTESVSQAHHTKHFVPVEKLGIASTVPMGINLATSSPLRDNLVHKSPLLAATQLFHNHSSPVGHSMLVTGEDFKLKLWEFKYLGQQGITNILVFRMNIFCNILAIHGPFSAEVMDKHYEDGHLQSLFIRRVGSINFEQIANITFRYGSHKPFSVEAEEQLHLYQQSNKFNPGFGENSSPSAGGLAAGKFGPEDHQFQQRNRFGIPLSQQDLFNSNHGMLPSSINMDNSQTLHPSFGNTNVLGGYAANFHPTNTGGFENGGFDHFPNQQGFQNFNNSSVNQLGNNFMGTQRPAWGNVGMGENGLSGLQYGQSATWPMGFSNNNLFMHQQQQVLPNQQHHSTIGVLNTHNLEKNIPPSSAFIAITSSAANTAAPASVSTSTGNNWGSFESSNILEHIGIDEDDHIHGSHFSVKEHPDVGKEIMENNNESLSGEVEEQEKDTLENIQQVEEQQEQNVPPKVEPSDKKKLKKKQKEEKRLQEKLKKEEEEKKLSNKVEKNKSNYLTSDEEPILIEETVVLEEVPKKTWAKPLVSTKSKVNLKEQLLLEEKLKKEEDRLKAERAKEMLLKETLYLKEMEAVGKTSLINKTSSVWGSSNSLVSGNEFLGAGGAIPLQQIILNEEQLSKQKKKKSNFQQPEQPFNEVNNNVENFNQGKRYADISNNKTNVIASAAPPTKWSVVGKKEVNNKVGVSTVNNTSLAARVGSNIKKEGGGIKPVNANSKPMEVKDTTVKKNLSALENEELIDWCKKTLAIIKSPQFDLKTFLDLLFLNELTDELLIFQICDATLGGYNMINSKKFCEEFLKRKKMLMEGGVGGEGFGWKEVKSVGGNASNAANTAGNGMQGFASKNKFQIVSSKGKKNRNLMKLSIIFLILLWALVTAQTTSDSPTRTTSKTTSKTATKTSSKTSFSKITSISKSQTSSSKLSTSSTSSTSSSSTATIFNGTVTTDSISTEEATTADAQETCAVNDPSCGDNTDNGVALGSSALSSFVPHLYPNFIFFLFYFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0K1</accession>
    <name>A0AAD5U0K1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="8">5.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Pentose-5-phosphate 3-epimerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">RPE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">HK099_005853</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000477">
        <property type="protein sequence ID" value="KAJ3216451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0K1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006163">
        <property type="term" value="P:purine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000191">
        <property type="entry name" value="ribulose-phosphate 3-epimerase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="16" id="KW-0170">Cobalt</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00030599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00057323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3216451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="20644" checksum="7073DACF4828E2DD" modified="2024-05-29" version="1">MGPQPHISPSMLSSDFANLAAEAKRMVDFGADYLHLDGAPVVKSLRKHTNAFLDCHLMVSEPEKWVKGDAGKLIDEIHKSGMKAGISVKPGTSVDTVIPFAGKADMILIMTVEPGFGGQSFMSSMLPKVKTLREKFPNLDIQVDGGLSNDNIDVATEAGANVIVAGTSIFSAPSPKDVISNFRSFILKNVTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Q1</accession>
    <name>A0AAD5U0Q1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004062</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000279">
        <property type="protein sequence ID" value="KAJ3220712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Q1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006709">
        <property type="entry name" value="SSU_processome_Utp14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150:SF12">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04615">
        <property type="entry name" value="Utp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="442"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="483"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="565"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="723"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="147"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="448"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="496"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="589"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="603"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="728"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1001" mass="114306" checksum="46F394ACF4467011" modified="2024-05-29" version="1">MPKNKRQKTRKEKKKINYDVFSDEEKVEKENPHLDSVTNYEYNVDKIKFEDDEEISEDEAFDDDDNEKYGEFFSQELDLNETDLEDEGEKGEDDEEDFDHDEDMMDISDLLNAEVKESKNSVKRQSHNLVDNEALQKTMSILLPDTHDEEETGELTNSEDENESIDSEASENEDDGLVTLISNLDTIKSGKKRKRTADEVTEAYEESEYNLTTSQNDSNLNGTKKKVNVSDLVGVLKDTTSFGGLKKHIEKLNKVSNNKENLGDTLAAPLAKRFHDKLNREAAYEQSKKEVGKWGHIVQKNRQAEHLNFPMNEAPKINLTSGSLISKFEANTEMENEIQAVLNDADLTEKKQKNLEELEMNKYTKEEVSIADRRAELAKMRSLMFFQEQKKKKIAKIKSKTYRKIQRKAKGHLSADLDLETLKSLDPEAAKEKLLQMERDRAKERMTLKHKNSGKWAKKMLSRKDTDSETRKALMEQLEKHEELKKKISGMHSSDDDFSGDEDDDDEEGDGGEDIANAVMELNSMKNSISDTQIPTTGVFAMKFMRKHVKEQLDASKRSIDELQEMLESERQHSSDFSENEEESKLDSNTKVSGRKGLNSTRTFDDNDKDLEQKFENTLTSSGPISIKKPVDPLKPLFEVESFEDSNLFEGSVNSNTINSSLKVSEVGDVDAHSSFKSDSLKDLKEEVPKGKIEDDFSGNESNAENPWLSSFSKPLLKSIKTNSQSFKEGKQEKALKKFAGDKKEKLRNSKIKNNDDTYEKLDITSIAEMEKAEVDEVTEEVTDSATIAAAEVNTVLTGKNETSDDFSVTKDMRKVIVESDDGADSDFEVDGERNHFNMMNKKDVSQLSQREVMRLAFADDNMFEVEFEKEKVSIMEKEKPQEIDVTLPGWGSWSGIGVKQKKKPSKKHIKKVDGIDIDKRKDSKLKNVIINEKRQKKSLKYQIPSVPHGFNNREQYEKTIRLPLGKEWQTSDTFQKLNKPKISTIDGKIIHPLSSKLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1F3</accession>
    <name>A0AAD5U1F3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">RAD15</name>
        <name evidence="20" type="ORF">HK099_005594</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="JADGJW010000442">
        <property type="protein sequence ID" value="KAJ3217138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1F3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045951">
        <property type="term" value="P:positive regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000135">
        <property type="entry name" value="DNA repair helicase RAD3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000128">
        <property type="entry name" value="Putative DNA repair helicase RAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001945">
        <property type="entry name" value="RAD3/XPD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00852">
        <property type="entry name" value="XRODRMPGMNTD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="7"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3217138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="779" mass="88050" checksum="36615639C98137CD" modified="2024-05-29" version="1">MKFELDGLPIIFPYDYIYPEQYSYMRDLKKALDGKGHCLLEMPSGTGKTVTLLSLIVAYQQHYGEHRKLIYCSRTVPEIEKALAELQNLMAYRKSHGESVEKFLGIGLTSRKNLCVHPEVSKVKGINAVDINCKKLTASFVRDQAKHAGEGTVELCSFFETLENAEDEIPSGVYTLENLKDFGKTNTYCPYFLARRLLPMANVIIYSYHYLLDPKVAELVSKELSKDSIVIFDEAHNIDNVCTESLSIDIFRPTLDASSLSDIKETNSEKLQSEYTRLVEGLRDVQQSRETDELMANPALPDDILKEAVPGNIRRAEHFVAFLRRFIEYLKTRMRVLHVVAESPISFLQHVKEVTFIEKKPLKFCAERLSSLIRSLELPDLPDLISLQRVANFATLVSTYQKGFILILEPFENDVDSIPNPVLHLTCLDATFAIKPVFDKFSSVIITSGTLSPLELYPTLLGFKPIVVESYQMSLTRNCFLPLLMNITQVITRGSDQVAVSSKFEVRNDLAVVRNYGNMLLEFSKIVPDGLVAFFPSYRYMESIVTAWNELGMLQDLLKFKLIFIETPDASETSLALENYRLACDNGRGAVLLSVARGKVSEGVDFDHNYGRAVILFGIPYQYTESRILKARLEYLRDNFKIRENDFLTFDAMRHGAQCVGRVLRGKTDYGLMLFADKRFARADKRSKLPKWINAGVTEAAINLSTDMAVTMAKKFLKSMAQPFEHSQLGISLWDTAMVVEANAKDVKKRSSIIEINGGSVGNQLNGMDMVEDDEMDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Q2</accession>
    <name>A0AAD5U1Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000223">
        <property type="protein sequence ID" value="KAJ3221554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Q2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="757" mass="86993" checksum="F9D873B5F35C3933" modified="2024-05-29" version="1">MSSTVDKQLELRKKLEEFKQKKLLEKNKKPTTTKTVRKPGPIKPTSKTAGVQQKIVTNKLDAQKSKVPLEKRIPTISSKTTKPVNTFNKKGTAEVFDVSKQTDKKKGKKWEVKDIETSPKKVLVLPNKDSFLSNIEEKENVEEDYNQYDDSDDGEDIIKNDIGENIFLDKPAPWVYKNQRKSKEKSEKFDNSVQKRDESSEDFFNFVNIRINVIKSRTLQDEVNAMNSEQGQQIHFMSDSSIQYSDEICQNSNSMAIHTVNKTDHLNFSDESSDGSDKSGFVIHEEFEEKGSVEYNFYKEENEKDSEELFQNAIELAEMGDEENSRKILLNLSCNEEINRRIDFWLTWYNIELKFNNLENCAKCLVQTDNLKKTHDDEQYIRSCIKHITLMLHKQNADSELVASSTEKDEQIDVVEVHDAEKKNDELNNFDVNEDPFNINKEQYDSSTKFLSNSAMQASTIFSNKISSFTIESDVESPLREAPEPSLLPGFSKEVIEYTEVSKQDSDLGTSKPNAETINDVVNLMNEMCIKNEENDESEEKLIKKVLDMRGSLTVLTPIKASKKERNMHGVKSVITPVRRSVRVLQQDDKLHGNKIDDVDIVEWGNEQQIEKLLEGNGYAYVPNKNIQLEKIKKVSVSGYTSPLKKRVNFDESRQSVDTDVTDVCDISEFTSNINPYSTNCEAESEIFSKNNNIPYRTQLTPFSKNNYFENNSFTPMPVTEKIGNRKKTPFTMNRFNDVLDYEDFEELSESGEHSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1R0</accession>
    <name>A0AAD5U1R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inositol polyphosphate 5-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">INPP5E</name>
        <name evidence="2" type="ORF">HK099_003670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000242">
        <property type="protein sequence ID" value="KAJ3221239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1R0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF275">
        <property type="entry name" value="LD06095P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="1">
        <location>
            <begin position="98"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="730" mass="83972" checksum="D7EFBF5CB0ED489A" modified="2024-05-29" version="1">MFCWCLNKKVSSKKLRAVFPISLKDETDHSFSFIHKKSHSEEVSATKEEAVETLPINPRRSSLLIQSISKNAHLSKLFHFQEDNLHRNRSKEVFSKKESLKVFIGTWNMNGKVPKVNLEGFLKSSKSCHLVVIGTQESQKSIEQSLIYSNFVKWETLLLHHLNLKKEKEAEQYELVKTDFLIALHISVFVLKKYKHLVKATDSGKIATGIGNVVGNKGAVAVSLLFGKVSILFVNSHLSAHQKRVAERNNDYNRINQELKLKGYFPTDAQYSNLVDKFDFVFWFGDLNYRINGLRKVVLLNNDQLFNEMKKGNAFKGFWEDAITFPPTYKYSVVDQQSEEKKLSTKRSQQSLEKNVLENQETYNQTNEENIGAQEITYADRNNTNEKEIKEKKKNISSIDNTNTHKYSTQSLVTDELQKKSCNEKEGKIFLKENHQSPLKYIKIKTKTCDEEQSITGFGNLQQECDLLKKGSPRSSTATTVHTSSESLCLNGNFIADTNVTSTSFDQSLKTSYQLLKKGNENFTNSYSFAYNPRQDRIPSWTDRILFKSRIKHHNDYKQLRKIEKLTKEKNESSPYDSKQWCGTVKNLEEKEEDINIGEMGSWVNLHLQRKKLSRERKKIDDMDFNAEEKICNNNFIEADGNLKKSTSDYSLSPRPTAMIKTLLYNSISEYTFSDHKPVIGAFLLNYEFDFLEEAVVRDDKGNPLDLFLNFSTQSALGSRGLLKDTCNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1R9</accession>
    <name>A0AAD5U1R9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="2">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ASN1</name>
        <name evidence="15" type="ORF">HK099_003672</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000242">
        <property type="protein sequence ID" value="KAJ3221241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1R9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000031">
        <property type="entry name" value="Asparagine synthase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006949">
        <property type="entry name" value="PRK09431.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="14">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="545"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="555"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="357"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="12">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3221241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="589" mass="66957" checksum="6D476597FBC47FFC" modified="2024-05-29" version="1">MRTKAVMLSKKIRHRGPDWSGCYSSTEHNNVLCHERLAIVGVDSGAQPLSNVDEDIILSVNGEIYNHVTLKKLLKKKHTFKTHSDCEIILHLYEEMGTDFLPLLDGMFSFILYDKKKDLYLVARDHVGITTLYQGFRSSDNSVWFASELKALNEDCDKIISFPPGSFYLSSAKKTTTYYKPNWYNHPKQEYPSLADENKKLTAAEEEKMYKTLRTALEKSVQKRLMSEVPYGVLLSGGLDSSLIASIAIRMKQQELNLPNDDDDVRSAMSLAATWPKLHSFSIGLKGSPDLIAAKKVADHLKTVHHEMNFTVREGLDALEEVIFHLETYDVTTIRASTPMYLLSRKIKAIGVKMVLSGEGSDEIFGGYLYFHKAPTAQALHHECITRTQNLHTSDNLRANKSTMAWGLEARVPFLDRAFLDVAMETVPANAKLTKKGPYNHPIEKYVLRKAFDTPENPYLPKDVLWRQKEQFSDGVGYSWIDGLKDHAEKEVTEAQLKSAKEKFPHDTPTTKEAYFYRTIFEKLFPQKACLESVVRWIPRKDWGCSEDPSGRAQSGHEEAYERAKLNGKNKEAHSSPSKKENSPKRQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Y1</accession>
    <name>A0AAD5U1Y1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">La ribonucleoprotein domain member 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LARP1B</name>
        <name evidence="5" type="ORF">HK099_003168</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000211">
        <property type="protein sequence ID" value="KAJ3221748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Y1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048255">
        <property type="term" value="P:mRNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006607">
        <property type="entry name" value="DM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF132">
        <property type="entry name" value="LA-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21071">
        <property type="entry name" value="LARP1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00684">
        <property type="entry name" value="DM15"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="457"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="335"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="623"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="768"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="854"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="628"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="856"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="872"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1104" mass="125061" checksum="3E0DDFBD1702C5E9" modified="2024-05-29" version="1">MTTVQPNSEVAENSQQIAFANEVEKKEVKPVPSPIPAVNVWKVRLAKQSQDSKLNQQKNENNINETQKTENQKKTPKYRSNDRSNYKLSEASGSNIKHNIENITEGDLDRDGFVKVVNSKHKKKEIKENYKIKNSKSYLKTDASRKDFKKTKNNSVLLENKEQNQANIEHPAEEINSTCESDATEIEDGTIEVNEKALTNGQLRTKVDSVESVEGKDLPKGVSSMPNSTLPTQKTPAKLVHVAARSENLITASEKSKTPKNFSSASVWPLLNKNSTEIVNETLSSTLKPEINTVTSAASSDLSNASEALTPAAPRKTAWSKVDLSIPTPVANSAEIAPSNTKTGNSAPKVMKKEESAKTIKGKKNTPNNFTKHAKKTVPTQNNENKTDNADSNISAEKIAPSVTNKPQQHFYKKKVNRKNGYQNKRYQHNYGGFNNQYQGYIIPQHQANFFPVDPELVNLDTVKWWIRCQIEYYFSIENLCRDIYFRQQMSTITGTVPLTLVSNFNRVKTLIALAKTKLPVSAAVSAIPNVEVSSLDLLLSALKDSEEVEIIDFNNEPSIRKRGDWEYWLLKFHNTEGDKTAAQPNSPFLVNNQISDAEDTLVKVHSNSENIISTAENSTPATISQLTTPDTSFSSPTTPKDEIDFDESSLKESDWRTTVRKKSGKTRLVPAKIEIKAIDTNVSADQLEHDVEESMFNFDDGEDWVGTKDLRKKPTFSAAVSNNKEDFGEGLVNTESIPMDDEDADEEWKDFDDDDIASLLIVTQLPKEHSKPSDSTQKHHITSNLDGEQRKAPRKHSTAPYDRSKMNDEINEMINEGLFFYERDLRKNFKERKTYQTVETVDEAHFKALKKPNTFEVTSNSPNSSIKSNQTSSATASAKSKPIGFSRRFIPVGSPVSASPPVGWLLGARQSQSNYIPSSSLGDTSPILTNVGSHQEIPVFHHPSHELLAENGFVQQKYSKFHAKALRERKLQGSGVSQEMNTLFRFWCHFLRDRFNMRMYQEFKKIALEDLQLGYRYGLECLFRFYSYGLEKKFKPDIFEEFQVLVVKDFKENKNLYGLEKFWAYLFYRNDKFKVNVEDKMDDELKNILKNFKSIKDFKSYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U234</accession>
    <name>A0AAD5U234_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Very-long-chain 3-oxoacyl-CoA reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_003406</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000223">
        <property type="protein sequence ID" value="KAJ3221561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U234"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05356">
        <property type="entry name" value="17beta-HSD1_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086:SF2">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086">
        <property type="entry name" value="VERY-LONG-CHAIN 3-OXOOACYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000126">
        <property type="entry name" value="11-beta-HSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="35716" checksum="2419C17993635562" modified="2024-05-29" version="1">METLTPLLVLSTIGSLFLLFNVLKLLKIVTFPILNHSKLSKYKTENSYALVTGASEGIGKEFAFQLAKKGFNLIISARTLEKLETIKKEIELETKVKVIVIPFDFSTTEERNFLEFEKKIENLNLTVLINNVAMNHSIPTPFLEEDEKLVQNIINCNITNTLKVTKIFLNLAKRENRKGLVVNVGSVAGLAPSAYLTVYAASKSFLRSWSIGLAHEVKSQGFHVEHVNTYFVVSNMSKIRKPSFTTPTPRNYVKSVLSQVGNSFSSTPYFSHAVLGYVIGFFSEKFLASTSASMHLNIRNRALRKRERESKNVKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U241</accession>
    <name>A0AAD5U241_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zinc finger CHCC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000208">
        <property type="protein sequence ID" value="KAJ3221802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U241"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="2">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="14913" checksum="43D6EDD099728096" modified="2024-05-29" version="1">MNLVIKSNRILNIFRITPKNVKLSTKSSTPATELKSELTLDEVLSQSPNRVEPWSKSQRPRKSALSGPRFEQIDLAAQPKPLAAIELINAEPIKIVHERVVACDGGGGALGHPKVYINLVSDHERIKFCIEFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2A1</accession>
    <name>A0AAD5U2A1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Store-operated calcium entry-associated regulatory factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Transmembrane protein 66</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_004939</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SARAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000366">
        <property type="protein sequence ID" value="KAJ3218756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2A1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006816">
        <property type="term" value="P:calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001256">
        <property type="term" value="P:regulation of store-operated calcium entry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009567">
        <property type="entry name" value="SARAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15929:SF0">
        <property type="entry name" value="STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06682">
        <property type="entry name" value="SARAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0732">Signal</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042085362" description="Store-operated calcium entry-associated regulatory factor" evidence="16">
        <location>
            <begin position="24"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="218"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="304"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="320"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3218756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="358" mass="40726" checksum="20D29A52E1239A9E" modified="2024-05-29" version="1">MKFKNSNSNLLLFTAIILSEVCSQRVLLRDIQTLTFQHGRQTKGRRSVVNQMTCIGGDARNHVNIKTIQCKNAGFDGRDVQWNCEANLSDDFEFGNIMVNCEGYDYPDDPYVLAGSCGIEYEIYRSQNKKRNNYDQQGNNNYNQKKNQKSNKKNFYSQKHKSYFGGDSIFSNILGNTFSNIKDIWSFIENLLIFVVVAYLLKQLYSWFTSPSPLGPPPSYSESTHRTSSRTQQNYNSQNHSSSSNSFPKKVFSSFPSLGFFSGFGLGNLFGSSFFGRNRYSGRHYRPNSSYRSNSSWFGRDTHYDHPDSRSDSSDEDNHTYASTTNTRNSGAFPNQNNSDYTSSTSTPVKGFGTTTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2A9</accession>
    <name>A0AAD5U2A9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000365">
        <property type="protein sequence ID" value="KAJ3218771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2A9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="147" mass="17872" checksum="91129696B82165FA" modified="2024-05-29" version="1">MIDRYNNKHFCRDDINLFITQMPSNIDDWKTSDDIRNKLLMCIISIGEIVKNLNQKRHFREYSNAWRTWYYHASWYILVRNQLCHMPLCSQFLSLNKSLEKRTVEEEYYEPYLVEEKYDKFGNSVGFIATEYKLEYAINKCIRTKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2P4</accession>
    <name>A0AAD5U2P4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pre-rRNA processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRP9</name>
        <name evidence="7" type="ORF">HK099_002389</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000179">
        <property type="protein sequence ID" value="KAJ3222352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2P4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039241">
        <property type="entry name" value="Rrp9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="266"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="308"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="435"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="548" mass="62628" checksum="A87E150FE7D6FC42" modified="2024-05-29" version="1">MKQTRIDPDQKIAKNKRKRIVKSKEQRKIDLKKEAKENFQFENEQFDENENDNKIEDDDDDSEAEIEKKETAAQKRLRLAKQYLQKVKEEVADDEDDDPDKDLIADRLKYDALEVAGKNFHKVAERYANLENVKIRTFKAKKNCHQQSITSISVAKLSERFLNKKSQDNSALNNHPVYIYSTSKDGSIVKWCFYTGKKLKYIPGLIKPTKRIKKKFNEKMITSNVGHNDHILCSATSMDGRFLVTGGKDKVIQIWSVLDDKNLGQFKQHRDAISCLVFRMGTNQLFSGSFDRSVKVWNVEELSYIETLFGHQDGITNIAALSKERCLTSGARDRTVRLWKIVEESQLIFRCAQTGEDDDLLLIEEGGDIKKKKKIIGASGGSVDTVCMIDEETFISGTDSGAISLWSVNKKKPVYTRLRCHGNGEIKEGKNLLGNNSYCNWITSLASLPYTDLFASGSCDGFVRLWKIHESKKSFSILSHFPCLGFINTLSFFYGPRIEVCENEKVNKEENFELNCLYLAIGVGQEHRLGRWWSCKEAKNCVKVVTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2R6</accession>
    <name>A0AAD5U2R6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fumarate hydratase</fullName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004116</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH. In cytoplasm and nucleus, involved in DNA repair in response to DNA damage: following DNA double-strand breaks (DSBs), translocates from the cytosol to the nucleus and promotes DNA repair by catalyzing the dehydration of L-malate to fumarate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000282">
        <property type="protein sequence ID" value="KAJ3220667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2R6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000002">
        <property type="entry name" value="Fumarate hydratase class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008909">
        <property type="entry name" value="PRK12273.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF1">
        <property type="entry name" value="FUMARATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="5">
        <location>
            <begin position="12"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarase C C-terminal" evidence="6">
        <location>
            <begin position="410"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00056821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3220667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="466" mass="50583" checksum="D2997F9D0B55D6D2" modified="2024-05-29" version="1">MADFRIEHDTIGEVNVPNDKYYGAQTQRSLQNFEIGGPNERMPELLIKAFGILKRSACKVNVTNALDKKLGDAIMTACDEVIEGKFMSHFPLVVWQTGSGTQTNMNVNEVVANRANELLGEVKKGTQSPVHPNDHVNMSQSSNDTFPTAMHIAALMSFNNDLVPALELLRDSLDEHVKNWNNIIKIGRTHLQDATPLSLSQEFSGYHTQVCYGIERIKNCYDKLGNLAIGGTAVGTGLNTRKGFAESVAKEIAEYTKLPFKSAPNKFEALAAHDAIVEASGALNVLAVSLMKIANDIRLLGSGPRCGLGELNLPANEPGSSIMPGKVNPTQCEAITMVCAQVMGNNVTITIAGSNGHLELNVFKPVMIKNLLHSTRLLSDSITSFTNNCVKGITPNIERISCLMKQSLMLVTALNGKLGYGNAAKIAKFAHHQGLSLKESAVKLGLLTEEEFDYHVNPEDMIGPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2T1</accession>
    <name>A0AAD5U2T1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ALDH3B2_2</name>
        <name evidence="9" type="ORF">HK099_002308</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000175">
        <property type="protein sequence ID" value="KAJ3222454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2T1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000003">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042166724" evidence="6">
        <location>
            <begin position="23"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="13"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="8">
        <location>
            <begin position="518"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="786" mass="89149" checksum="2198531429292453" modified="2024-05-29" version="1" fragment="single">PTLRLFLLLITMTSQNIPQIYQEVKSNFDKGLSLPLSFRKQQLRKLYNLLEENKELIFEAVKKDLGRPTFEANLGEVVPVQGDVVDALENFEDWAKTEYPSVSLHNKADRCEIRKQPKGVVLIISPWNYPVQLLLAPLVGAISAGCAALLKPSEISKNSAKLLSELIPKYLDQRIYRVILGEVPETTKLLELKFDHIFYTGSTSVGKIVMAAAAKHLTSVTLELGGKSPVIVDKSLTDPEIKTISHRIAWGKFINNGQTCIAPDYVLVHPSKKNVLVEGLKAAVNEYYTSNPEASRDYGRIISLNHHNRLTTLLKKQIETNINSKIILGGKSDPSVLFLEPTIVEGVGMDSKINPLMADEIFGPILPIIEANLEESLKYINQNERPLALYYFGSKKTDIEMVLNSTWSGGCVVNDVLMHFLEPALPFGGTGASGIGSYHFKKSFDAFTHERSTMIRSLGREAANKLRYPPYKDSNTKMMLWVLSKKPKGSIQQLVSRIIRQIVRNFGFIGWVIAVGLKESKTADLVIKAVLNGFRAIDTACQPKHYQEHLVGVAISTLEREFNIPREQLFVQTKFTSIDGQDPNRIPYHKNFSVPEQVKESFSISLKNLKVNYIDSLILHGPLDTVEDTISVWREFESFKTYELVKFIGVSNFYNLEAFKIFFDQCRIKPMFIQNRFYKGTNYDKELRKFCKDSNIIYQSFWSLSANPHILKSKVVDDVLQRLAKVKGKAVTREQVFYRYLMKLDIIPLNGTTNEKHMKEDIEVLEWNDLNGDLTDEEINNISELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U349</accession>
    <name>A0AAD5U349_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_003797</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000253">
        <property type="protein sequence ID" value="KAJ3221080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U349"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="F-BAR" evidence="9">
        <location>
            <begin position="1"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="408"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="469" mass="54508" checksum="3F22ED7EC05D784B" modified="2024-05-29" version="1">MQSFNNSFWGENERGLEVLMQRMKMGKHINEQIFALFKERALIEEEYSKRLSKLHKNFIVKEEIGTLRSALDVLKNELEISSKSHNDMAIEIKNQLEKQTQDFIIQQSGIRKSHQVIVEKIQKNKSQLISQVLKTKEKYELKCQESLQLLQMRKNPLPPKEAERTKKSLDKAQQLANQLDFDYLAGVEKLQEVHKKWEEDMRTCCTDCQKLEEDRIDYLRTKLWTYANLISTTCVSDGIFINQLLNLTITDEGCERIRVSLEKCDIEKDIQEFLEKSATGSEIPPPLQYINFYTQTNERPISGVDQLNSLKKSVSQLTLTPGLFQQQQLPQYNSSNKLLNEQLQFSSSIESRSVKTFNEAITIQNDNLSRPGVNNNTLPRPVSVKGNVDLSNETYFHYDPYDIEDQLKILFSVKVLYDYQAQAFEELNVKKDQIISVIAKHDDGWWEGIIMEEGKRKKGLFPSNFVEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3R4</accession>
    <name>A0AAD5U3R4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000141">
        <property type="protein sequence ID" value="KAJ3223166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3R4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039136">
        <property type="entry name" value="NUFIP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019496">
        <property type="entry name" value="NUFIP1_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309:SF0">
        <property type="entry name" value="FMR1-INTERACTING PROTEIN NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309">
        <property type="entry name" value="NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10453">
        <property type="entry name" value="NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="57430" checksum="289AD2DE60EADADF" modified="2024-05-29" version="1">MNNNNHNHPKYPSPQHMQFSQHSAYPPPQQYYHQPPQQFQVQPQQPIYTTMQVPFYNNAYYNQAAVYHHQNQTLQHFQQQLEQTKFSLIPPAYNPPKPYIFPKKNQIHKQNNNKFQHGNGRFNNPTKLPSDLECKNCEKKFQQQSQLDAHLKSHVNCTECDFVGLKKFVDDHITEVHKIQSQPNMTHHKKKFVIETEEEIKKYIEDRKKKYPTDSNVSRKLEETEAKKRKNESKHMSNLKNEKKQKLIEKNIHCPVFVSGNCTKGQLCEFLHEIPSSISKADTLNLEENVEGNNRKKKNNKSRKNNKKKEHENFKVQNITDGKRKNLLKMLLEPEIKRERNIIFQFCKYLVKTNFLKDTSDVGVKMVAGFKICKDDKELIRKEKELLLVKGANAEDDESSGSETSLDDGDEQLCDPVLLKKNYLMADDDTDLLADENMEDLEVEEVDLIVREIHSSNSSLNYVELVKLVLTKVDGRTTKKVISNSVKKLLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3S5</accession>
    <name>A0AAD5U3S5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000128">
        <property type="protein sequence ID" value="KAJ3223484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3S5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37849">
        <property type="entry name" value="YALI0E11605P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37849:SF1">
        <property type="entry name" value="YALI0E11605P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="143" mass="16146" checksum="A6984B00764FD41C" modified="2024-05-29" version="1">MNFLLRSSQRNNAFFKNQNLFNKSIRFQSSSPTSSGMRGGIIGFLFGLTTAGATGYVYLIDEYQNASHALLLSVEDVAKSTNKLKQNTNKVDALERDFKEFKSTAASQVELDSLKNEVLKLIDEINISHLNLKTDVWDLKHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U418</accession>
    <name>A0AAD5U418_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000280">
        <property type="protein sequence ID" value="KAJ3220694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U418"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="437" mass="50249" checksum="4596CC014F5F8FFE" modified="2024-05-29" version="1">MDSFLREESIDSPCFFDNKDTESSQLTCSPEFQNKCLQEPTPVRTQSQCSSLLSKYKSNPSINSHGMSTKGSIKNAGESFSTSKLSVFKLDSELQRLWKTENSKLWLENFFKVNLDLELKNRKESSENSIKNLEHKLNNIEFNVTSQIEQFQKQFETLENEVKTNFKELNAYINQTNTCLQKMREDQLKLSLALKANGENVKKSLDSQKENYASNEQFNEFTRKLEQDIKQLIVEGTNTVSSDIEKKIKIAEQQIGEKMACFEKNVKDLNADIAAKNKAEKKQEQESNFRGLPNFDFPTPKNQYLYKINDQNQSKILNLSGCSYNVQIADSSKLTNRKQNNDNFHGDQNNVNLTLPKSISNNKILQFSNKNVSSLNTLNITRSEFFPKNYQKNFNQNGCDTDFFSNNFFPVPHLNKNLEVVEKELVKGLVLKLINCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U458</accession>
    <name>A0AAD5U458_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">anthranilate synthase</fullName>
            <ecNumber evidence="3">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000389">
        <property type="protein sequence ID" value="KAJ3218250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U458"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="9">
        <location>
            <begin position="68"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="8">
        <location>
            <begin position="245"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3218250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="525" mass="59223" checksum="0F6F54237DEFAE68" modified="2024-05-29" version="1">MEIFSPTLEEIVSLVKAKKGNLIPIYSEISSDLLTPVSVYSKLAYSSKNKVTSSKLDNDNGLRYNTPGAYSFLFESVAGGEKIGRFSFIGANPQKVLHVGENEYIHGDPLITLEKYLDHINFVPVNGLPGFTGGAVGYVSYDCVRFFEPKTANKELADPLNIPDAVFMFCDTIIIFDHLHHVIKVCSHFKVNENFSSTESEIKKEYERVQLEILDIIKTLNDDITPLPFQTEILLNEPSVSNVGKEGYQKFVGDLKFHINEGNIIQGVPSQRIRKKTTLHPFNAYRQLRSTNPSPYMFYVDLGAFQLVGASPEMLVKVDETMTVFTHPIAGTRKRGKTPEEDHNLAVELLSDLKERSEHIMLVDLGRNDMNRICEPSSVKLDSLMHIEKYSHVMHIVSHVSGKLRKEKTRFDAFRSIFPAGTVSGAPKVKAMELIYELEKEKRGIYAGAVGYFSYSGNLDTCIAIRTVQGYVYFQAGGGIVYDSNPEDEYEETINKLKSNITAIEKAELFHFNKMKEELKNFVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U466</accession>
    <name>A0AAD5U466_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_000746</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000119">
        <property type="protein sequence ID" value="KAJ3223726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U466"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="233" mass="25720" checksum="0894B96B887AB57E" modified="2024-05-29" version="1">MPLTSDQPEPTSQKELVQKLLDDKRLNLTSSVAQIMEKVDRKNFVDPSNTYGPYEYRAPSIGYGATISAPYIHADALVHFEQHLKPGMKVLDVGSGSGYLVACFAEWLGPTSTIVGIDHIEHLVEQSKENIKKGNANLLNGNNVKLVVGDGRKGWKQEGPYDAIHVGAGASMLHNDLIEQLNSPGVLILPVILEDKSQVLKKIEKNSQQQITETVLRNVKFIPLTSKEEQLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4F1</accession>
    <name>A0AAD5U4F1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD repeat-containing protein 43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">WDR43</name>
        <name evidence="7" type="ORF">HK099_002243</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000173">
        <property type="protein sequence ID" value="KAJ3222489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4F1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="6">
        <location>
            <begin position="420"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="546"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="546"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="580"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="619" mass="69499" checksum="A3B7EF992CE7F1C5" modified="2024-05-29" version="1">MTTQNTILTTFGSDDYWAQLQKSIKSNEIIVYQSQQLISRLDLNSEIPTCLTFHSIQQVKKVKGKKSTKLSKLLGVGLDSGDIIFFSVESASITFQLKNGHTNKVTDITIIGNTLYSCSLDGFVVEWDLNTNSQKSKFKAHSKSVKKIAKSYNEKFLLTADFDIKLWDVEKKTCLKTFNGHATDVTQLLFTVDDKLCISCADQDRYLSIWDVDVNGASTNVAALRLDVPPLKIATSIKGHVLALTETGELQLFNEPNITVNIPTPKKKKNKSIQTVKPQSAVGVVNLIDGEKKMEILDANFTAEKIEIVWGKTLKPNFEYLDYVNSSGNIIEKIELDRHSTALFADENSFESMSKIQDYSEKEVVITNSFDKLTHQTAKQKDSTLQEKLESMTLHTKSSENQIPTATSLNSILSQAIHSNDKLLLEKCLGVRDTKVIFTTVARLSPHQAVPLLELVLNRLQNKPSRAKTLVEWVRAVFLAHASYLMSNTALVDRLSVLYSTLDARIVTHQKLCKLSGRLDLIASGIERRTKTATETFEDEGALIYNESEEEPSDDELMEEVIGDADDLDDYDMIGNKEDLSDEELSEEEEEDQFSDNDVDGEIEDKEEDFDDIESDEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4Q4</accession>
    <name>A0AAD5U4Q4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000236">
        <property type="protein sequence ID" value="KAJ3221330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4Q4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="268" mass="31322" checksum="FD33E13BDA0B320A" modified="2024-05-29" version="1">MLLIKLLNLITHNTLFKNNDQNTAQTSFGLSEDYEKFPKPKNIDCKEYFVQSSTYQTFDLQQSTNLPTLTKKQKFDEAVNYITSKFNTTRDQISVTSVYDTSFSSFYFKPLINSIQVKNAEANLNLDNFGKVMSFGEFWIKPTSKNFKKKKNLSPLQSLFIVNDRFLNFKFDQNLMEVEKDFITFNNGYDELLIQDSIIIKNLPFIKGGNVNIAEKFYRTQDEEIFNVWEVSIPMLFHRNPSDDTWYTFLIDSSTGHCMGYFDSVIHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U506</accession>
    <name>A0AAD5U506_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000090">
        <property type="protein sequence ID" value="KAJ3224527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U506"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031537">
        <property type="entry name" value="DUF5092"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17010">
        <property type="entry name" value="DUF5092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="593" mass="66130" checksum="22D4518A09B2E3DE" modified="2024-05-29" version="1" fragment="single">MSDIIQLLDSSGSSVIDSVSVEYEDSFSLETFGDLAKAFYDSGAKSFIIARVQTWDHKQPDKAFYSYYHAFHLNKILFQTQVYLGKKLIHRLHVLNPLTNTDIIGSVQYFMVKKRGEPLIFPKKNSKGTNGGSILASNIAEDQVNIPEAKIIPNLSNDLESQVTQNFPNNDKKRKSSMKPAKIDTKLDNTSLTLTDGLQSSTIKEVESGVKQAWNSGPAVIVEEEDSEKPTEHKPGYRRITFSKTSRIRALSFKHAINPPQSPVRNDTINIPITPLSAPPAPIMEPSLSVEQRKRACSIDGETSNLEIADSQQFKRRNTAVTVSMLPSASPLQVGAANQVKKTVLPGSVTKFGIKVTENDLKSIAPPTVKSRRRSLSYANAITAAGTQATLEEWREMVLKEKQSIDLEHDTDYDKVKTFGTPTNGNIPPLSPVKVSSPLKSPRKESIKEKIEAIKEEQEIGLEGAEVLKVEEELMWDATLFATDTDFLESSKTRVKFKDNALVPEDAMLFKMKEYTGEEIASVEVIMDDRVFFLDCCYPTQQQLQNSSPLMRIFHHFKCYALAMTLMTGIFLFIFFTLKSSQKATGATTLPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5R7</accession>
    <name>A0AAD5U5R7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006803</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000061">
        <property type="protein sequence ID" value="KAJ3225432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5R7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="470" mass="52977" checksum="F73DC34127045583" modified="2024-05-29" version="1">MDSYELTAFEKTLLNAPADFCVENTKIDGNGVFGSLDKNFKYNDLIAAKQEESKTKSKLLTEVSTFQTAYQGKLGTVDATSAVQNKELLVDLESNLSPVLHEADKLSPSFSSALTHQLSSYQISKQRKKSLASDLSFSSTQSPLSSVLSTFTFEKNYSMVQDTDHPSSSGMNQNKYYSISNSIEPSTIHNVEEYPPVIPARKSSNNHNSQEKIQIRPRKDSLHWEEKIHLKKESLNESKEELCTEKKQSLNFSLQVSESQLIDKNSPILSEYDVTSDSRDETEELSIEKKTLSTITIFTDASIIDYLRGIEEYQLEISDEDYSLEINADKQSDYGRISVLTDNEVENKFLDEIIEKLEDARETKIKRTSGKIRSFSLNSNSTSSILSLLNSLGKEEKSVTIANEGKEEISVVANQNTDDSTVTSTIKWNSQLNSNKIDLMSIRNHMSMIRLNLESKKENQNLKNINKTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Z4</accession>
    <name>A0AAD5U5Z4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000056">
        <property type="protein sequence ID" value="KAJ3225635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Z4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="209" mass="24466" checksum="211390C60CE53C52" modified="2024-05-29" version="1">MQLTFEKGERQRSILWNNNIHGSGDIFIRLGAEYSLKKRKDGSTYMKHYDLTKSPKVPLGLSVILPETLPHMFRLESHRKMGCTNLPKPTRYYRLPYPETEPVQYCHHFVLYPAREMTVIELEAELKNLGWADCDLKASGLPISLLYEDEDDDVDAKLDKVDDHRLRQIHRIVIFSYEISTNAMDDILLLEVRQWILETNPLFEDLLCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U605</accession>
    <name>A0AAD5U605_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000165">
        <property type="protein sequence ID" value="KAJ3222650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U605"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="21798" checksum="DBE244FBF056F454" modified="2024-05-29" version="1">MSTFNICTTLPQTTIDDLRNNGAEVRDACEIIVFNVLDPQPIEIFDKFLQADKEVDPLLTPHFGNPAAPYVAYNIQLEIYQLLHAYQQIPAANLVPVPQLTPIANLVIPPGGGYQYHYAQIAINYVMKQIENPDVGFGLVGLPHVPSGTYVDYADFKKKIAKEVINNSLSQEQYLLSNKKHHSEEFKLAALYAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U654</accession>
    <name>A0AAD5U654_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2062 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000171">
        <property type="protein sequence ID" value="KAJ3222535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U654"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018639">
        <property type="entry name" value="DUF2062"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35102">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35102:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09835">
        <property type="entry name" value="DUF2062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2062" evidence="2">
        <location>
            <begin position="86"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="21216" checksum="2092B8E22CDD47F8" modified="2024-05-29" version="1">MEESTLELKPLISNPKVLVNKTSTTNLKQKLLKQLKNQKSLSESSLIEGEQNLDDVENKKDSTYVKKVIIEPFLTALKTGSSINELTLTITLGIVLGLFPILGLSSVICLVLALVFKLNLPLIQVVNFSLTPFAFALCVPFFKFGTFLLRFDVDSFLPNSLWNKVYSEPILGLKIIISGIFGWLIICLPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U696</accession>
    <name>A0AAD5U696_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">NEDD8-activating enzyme E1 regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">APP-BP1</name>
        <name evidence="7" type="ORF">HK099_005953</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U696"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01493">
        <property type="entry name" value="APPBP1_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000475">
        <property type="entry name" value="NEDD8-activating enzyme E1 regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030667">
        <property type="entry name" value="APP-BP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF29">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039099">
        <property type="entry name" value="APP-BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="6">
        <location>
            <begin position="11"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="542" mass="61513" checksum="6AAB042505FE050E" modified="2024-05-29" version="1">MQQPNTKTQRYDRQLRLWHNHGQQALENSKVLLINGSATGTEILKNLVLPGIQSFTVLDGNKVANADLGNNFFLTRESVGKSRSKEVTDLLRELNNDVEGNHLEEDPTNLINNDLNFFKKFTIVVASQLIEVELLKLSAFLWENNIPLIVVRTYGFIGYLRIAVPEHTVVETHPEQIVDLRLDSPFKELSTFANSFDFSTMTSFELSHVPYVVLLLRSLGEFRQQYGHLPSSTNEKNEFKNLIKQKMSGVTSETENFDEALSSAFRTYSPTSNTQSILQDEKISNLNLKSTNFWILAKALKSFIENEGNGFLPVAGTLPDMKSDTTSYVELQTIYKNKAKQDVASVNNYLLEILNNLGKPKDSIPLEEVERFCKNANFLRVIKYRSLNDEYLNASTTLGFTTNDILHLTVLKKKKFFYKGKLLEDLNSNVVFFVLIRAVDSFWEKYRRYPGVHNSEVDADIPLLKRCTQNLLQGWGVNPGLIQDDHIHCMVRAGACEMHNMAAIQGGIVAQEIIKILTGQYIPLDNSFIFNGMNSTSTTFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6H2</accession>
    <name>A0AAD5U6H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000210">
        <property type="protein sequence ID" value="KAJ3221760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6H2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="311" mass="36194" checksum="01DEEEB780D7FD45" modified="2024-05-29" version="1">MFVKELESKFTCKFKPAKPLIHSTCIFWKHYLIWSGLPNLEEFYIIYDYLTDPETGKISDGLINMTKSKDVPLISTKKINLTSNCNYNFNNVHHNVVADPAHRVKDFLIGPTLSDLEREEKYFTKNSPSNFLTEKPKSVYIGKEGREAKLLCYQFEEDLTILLFLSPDTVTFKDNNTCNKISSKINETKENVISSNPNGIDEIYSDLPNNRNIHCNYDLKFYKDLISFFDEKLPDLNAVIELEFNQTQKFSENIKKSANFFEIQLKSSSKFWSCGKLEEEKELILVVPKEEYNLIDINVEFQKLTTLLYGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6M3</accession>
    <name>A0AAD5U6M3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6M3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="59" mass="6198" checksum="BEEE7F8D8FE2F4CD" modified="2024-05-29" version="1">MSDTGSYIVVFKAGTSKEKIDEAASKVESSGAPLQALDHLDFIESDGEVSIVAKNLGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6V0</accession>
    <name>A0AAD5U6V0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DNA ligase</fullName>
            <ecNumber evidence="15">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">LIG4</name>
        <name evidence="19" type="ORF">HK099_004421</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="15"/>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6V0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07903">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07968">
        <property type="entry name" value="OBF_DNA_ligase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044125">
        <property type="entry name" value="Adenylation_DNA_ligase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029710">
        <property type="entry name" value="LIG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45997:SF1">
        <property type="entry name" value="DNA LIGASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 15 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="17">
        <location>
            <begin position="329"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="18">
        <location>
            <begin position="631"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="18">
        <location>
            <begin position="867"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3226677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="946" mass="109039" checksum="F7A3BF3225F29CA3" modified="2024-05-29" version="1">MTDDNSAKPQLDSLITFSHIVNLFQTLEKKKGKKQDVLIGFHQFWKKRDKHSQTYPYIRLLCPSSDRERNTYGLKELTLAKSSSVGSFSNSLYDILSNRCVVQHGTITISDVNKKLDELCLNQERESQEEVLRYFYMNCTAEEQKWIVRIILKDLKIGISADTVLTHYHPDALEQFNVTNDLKKVAVELMDYDVRVPAPQISLFNAFTPMLSQKTSIDDVLKAMKGNTFWVETKLDGERIQMHKDGSNYQWFSRKSHSYTYLYGSHESEGALCNLIHKSFRNEVKNCILDGEMLALNTETGRFLPFGNLKTAALDAKANGLNAKLRPFFRVFDCLFLNGKCIMESPLEKRYGFMLKIFEPQKNIFDVVPHAEGNTVEDVIRLLDESMLKLEEGIIIKNPLSLYKPSSRGEDWLKLKADYMDSIGDNLDLLIVGGSWGEGRRGGKLSNFLLAVFDEDRKKFISVGKCGSGYNYQELDEILRVTEGKWKPYNAKNPPSWLIHDYDNKNREKPGIPILKLTEKLFSLKDMVISPEHSKIVEVLCAEIVVTDMYECNFTLRFPRFVKLREDKGPDDCLTFLQLKEIIRHTRGKLRSRTAKSLHEESIRKKRVIAPRTVIGVSVENLAVNVKEIEKIGIIFKNLEFCVLADGIEFKLNDKFQTKHDVERVIIANGGNVVQNPVSTTNFVVSDKLTVRVNNLISGKRFDVIRTNYIYNCLNAGEVIQLNSRYLLFATDFTKAKLNSIADKYGDLYEEQLTESSLKELFFSMDMTSIEKKYRESEEFQYRGLKKKRRKTILEIEERYFGLTPNPGGLFRRVVAYLDSSTTIKVSPNFIQENFCDDKVSLISPEDESYLHLENKRDSDLEISRLILLSKGASVVDVWCEDVTHLILDDDIESTTLDRFLKILTSLKDRHERRPHIVYKNWIKDCCYNETLLPEENYRPRSSAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7C2</accession>
    <name>A0AAD5U7C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynactin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DCTN6</name>
        <name evidence="7" type="ORF">HK099_003340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7C2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027777">
        <property type="entry name" value="DCTN6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072">
        <property type="entry name" value="DYNACTIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072:SF0">
        <property type="entry name" value="DYNACTIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="164" mass="18124" checksum="1AC48EB53D429D7F" modified="2024-05-29" version="1">MSLICSNAIIEAPVTFGENTTVHPKAHIKATGGGAIIFGSNNIINERAVINNLTAAPLIIGDNNVFNVGCLFEGKRMGSNNTLESKSFAMKNSVFGDNIILGSKCSVNEQIDDFMVIYGKDNVWRKVQEGNSMKKFNDNQVLHSKHLDYLKEVLPKYHTIKKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7D3</accession>
    <name>A0AAD5U7D3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7D3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="608" mass="69055" checksum="B2EA6593AB56FDA2" modified="2024-05-29" version="1">MADDELQRILISVSVTTQIGGYSFRTQREYLATGSTYSALAKKQNWIKSEDEAFPIQLDTFHKYVDYELERVKSGALQLKSFKRNIAKLDLYHKEMLKLNFSGIRNNSDIISKIDNFVKLNSDNVKSPAKSTGKFVADNKSTTEISTEGKSLIEIPQVTGKKLETEKQYTAEKKSHEVCSEKLDIDNEYIHYLGKVKIKPTGKLSAPTQKNRAGYNTYANLMLKGGWVISIENAFPITLKLLHHYLDYQLERVALGFLKLETLRKTNLGNLFAYHNCLGYDWSEVRYHPSVLKKLVVKEVEHGKDFQSISSSYLTPQYSSKITDSKIKDKVKNVDIVVDAMQEVLSEEDESVNLDVIRNNIQENRKRNDNITCNEDEFTKSFSDSESSNTSSLKSGKFKSKHEYERKMGMDETAFEENAENNASGNTIQHSVNNTGTESTNSSGAPLNITSLMKKRSVSESDDFETFPSTDGNKNQHAEHYDKKYIPYLCNTSKKQKKQPLQSFHEKDFLALLSDAHKSEKKLDDSMASVENFCNSSGTNLKVNCLNISNEPEGAEIVEGTTNDLRRIELNLQLKIEENKTKKINLCSKMFENGASLEFLKNFLELLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7J3</accession>
    <name>A0AAD5U7J3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cilia- and flagella-associated protein 91</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MAATS1</name>
        <name evidence="13" type="ORF">HK099_006076</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CFAP91 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000050">
        <property type="protein sequence ID" value="KAJ3225873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7J3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026720">
        <property type="entry name" value="CFAP91"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032840">
        <property type="entry name" value="CFAP91_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22455">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22455:SF10">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14738">
        <property type="entry name" value="CFAP91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="11">
        <location>
            <begin position="186"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="CFAP91" evidence="12">
        <location>
            <begin position="590"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="952"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1205"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="703"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3225873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1241" mass="143397" checksum="87602DC8D968C35C" modified="2024-05-29" version="1">MIFNRLSIFVDYNHEEEQSLLPDINVQNNALVVKKTSFIDFIQSEIIYLATFSVHAIQQIKSGLSHHKVITLDPERSDWRLDHTIMSKCFQGLLDFNGHSIARTRFLQTLIPKVLPWNVYVVPFSFHVNLETLLVEENKVKAKNPRLFSTHYILPDEINAKNEFTLSGEWVSWGKLDNVQEKKKVILYLHGGAYFAGSTKTHRQLVWRYAKESGAKIFVVNYRLAPENPFPAQLHDAYACFLYLTNPGHPAFKSSGFFSSNYPLHNPIAPSDITLMGDSAGGGLCMSLLSYLKNYLSIPSVADYLVSKDECKQSSCSLLPKTLPNGAVLLSPWLDLTCSMESWKTNASTDYLFRMEFFSDIHHVGSKNPVYWYTYGEEKLFGKDYLNWGRKWFMDKEFKKDDLHVLELTSKVVSHPLVSPYFLDHENLQGFCPILIQAGDAEVLRDESLFMAHKLFVANSALNKEGLIRHELYRHMPHVFPAFVWLETSIVSIKSVGKFIRKLNNEKNSNLIDAVDGIFSINKFEDRYSLPYANAKSGLLLERVDSSLPIIPYQPSMGGTIVYAKKPIKKVDSDSGKERAASPLFRSSHVQTVFRESFSQTEPYSPEYIISSSSKTTPELLALATLTYGAGLPVGQQELEMIERARLKRAWEASLPKVVDQKSFEKRLKMMEEMELKEWIERDEEIKRIQEARLVVLEKVIRKREAENECINAERIEKIWQRKLQDRNACMDRIQAKRIKALRKLSEKREQVGIDFQRRDIIQEYADFGSKIYAPKTRDGVFKDRTVTTLCVQISQLKEHLGIEQLEAQIPDSIFLPDINQPSVKKSFVTKVRMDQQMQQQLNLMDLRLKEKKMLHLESKKRPQETQLKFSQKIQKSPIRPPFPIIPETAEDEIRKEENAIFLQKLIRGIIVQNFMYQGKQRRLSLINELKMRYKIEQGLVKLKEFEKKNTLEEEDEHSFKNSDSFVEGENGHAQGNLNSDKIVHEIEDQEFSFHIDSHAKNEDNFKIKPLSARKAIQSNLQSEYIAKTFDFLTKELTRLRQEKVIAAVVRLAERTRRLREAEERGCREEEIKRRDIEDQVFKQLISVNQETVESFLETIVEDSISHTSKVQARIKVRDYAAKINDVVDGLEKRKEKGENIIDNTVQDLVSSFLIPEVEKNCLREKVKLNQKRFLLAAHRTVYSQQPAIEQNLADLKEKQDSLRIEQSKSNRKMLSKGNSSISMAKIGSKSSRKIEDINDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7M7</accession>
    <name>A0AAD5U7M7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome biogenesis protein SLX9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000047">
        <property type="protein sequence ID" value="KAJ3225980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7M7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028160">
        <property type="entry name" value="Slx9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15341">
        <property type="entry name" value="SLX9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="66"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="572" mass="65774" checksum="F439B21C4E5DB588" modified="2024-05-29" version="1">MGKIVKERSYKTSGPGNKEVTLENFGGSKSCSLGKKEWKKQKKEMWLKKVADFLEKKDKKFNNKKKKMSEIPNMDSFKEAMLEITKNEEQKPKEEKNIKINKKAVSQKHRRKVALEEITRVQKILKYKKFSENPISIIQAHINNTIANYELEFNFFKDQIQDSNLISENSGFGKVYKVSNIEGKTVCLKSENLCDILTGPNNEGSPLPNSLVESYFKDLVNGLNFLHSWDIAHLDIKPENLLIEKSTNNLLITDFGSSININKELPQNYTPYISEFWSAPELNSFDSTYFDDKKKFFKCDIFSCGLIFLAMYHGYKNLELFTNNCSVLTPSNISKAIQKIDSENWRKTLTEMLAMESRSISLNFILEIHYNFSIFRKPDFKNEEKSLAKKVTNDALEKHLQGSAQLNRNFFSSSTSIGSSSDFNFCRSFNNLQLSNKSVSSLLSSSNSQYEKPIQRREDSSHSLNKSTNTLHLVSTKTLSSRKSTHLPSTETIYNSAIDLNSTNIDAKFKKSISKMNKGKDISKLEIKSEKEFNDDFRGFTPPVAPRPNKKLIEKVREERLKELNLYFLNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U899</accession>
    <name>A0AAD5U899_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U899"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003830">
        <property type="term" value="F:beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006813">
        <property type="entry name" value="Glyco_trans_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224:SF0">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04724">
        <property type="entry name" value="Glyco_transf_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="435" mass="51056" checksum="1FB15B74FFE88247" modified="2024-05-29" version="1">MNEVNEDIPLMDLRDHRNQRLTTLEIPGGVNIERRQHSQQRNNSDRNLSRSSSQQRTNRIDTVKKISKLKLLWHACEYKSEIDRWKIINNLGFPNNLSDPEVFCKLHNFNPRENYFNNVKYVNNKIKVFDVFLFSFELDLLEVRLNELYDVIDKFVIIEVPCTTKNRPKELLFKQSMRENNFRRFLDKIEYVVFEDFCLLEMKGKQYQDELRSRTIKSARDAGAVDGDLFLFSELEEIPRASSIRLLTKCDFGSRINLMLDSFEFRLYPSFVFKSTVSVIGRINDEKIHSRFSYLSDLLLGDAGWHCSWCFRHIGDIQKKMIGYSHSDGVNFNMKLLEENSIEKKLCDGRNPFDYLPQAKEFSELFEQWSSIRSLRNNPIKFRYLLPGGCVVDIVEAGVISGKCVSIPEEEVNLFGCNDHLIRIAKFGEDKELIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8P3</accession>
    <name>A0AAD5U8P3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8P3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="396" mass="45775" checksum="126A25D98858EC25" modified="2024-05-29" version="1">MNNAQYIAKRTFYSTPLSYQIIFPKQENLLTFSTKNHQIQNKHLIKYFTTLRPNQLKIVDNTFLIGNLKTFNLLKKSDFSKSSLYFSKKGTVQNESFIKEFSTLTPYPLTVNGNSTNLMGNLKNYRSLKEKLFHSSARNFSSNVVVVKETMFSKFIKILGWGTLICVVAPLGLQLIGITIGPVFTILFAGFTIAFVAAVLVVTFVPVLIILCVAGLIVSIPISKYYFALKEFRKESMMNEEFLILTKNELKKKKGGLNNCDIEEEFENEFKEKINKKHRGKKEVSFKRKNFGEGFEININDVNGEIKTSNSSYLKNDEFTEYFDETLFKRVKERYINVARLCEEEVSRREALGEKFGDDGRVYLYKESWPISIVFPVNVNWVRKQNNFDNVTQIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8W7</accession>
    <name>A0AAD5U8W7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000798</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8W7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="4">
        <location>
            <begin position="30"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="161" mass="18229" checksum="F5121BC5F0C8F5A6" modified="2024-05-29" version="1">MSISSITGKRAEPLFAKKGDSTKKIREGMPMGAKVDLTGKDMYEFLDKLKETVLPRLREWEGVHPSMGRDGSITISLPDHAVGYFPDIEPHFDMYPRLFDTDIKIFSNCANEKDLVLLLSGFGIPFSPKVYVKKTNENGKDPWARYRKKGSSTEVTIKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U957</accession>
    <name>A0AAD5U957_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_007320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U957"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045347">
        <property type="entry name" value="HIND"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19252">
        <property type="entry name" value="HIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="110"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3228039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="159" mass="18822" checksum="25A156E61A19DC54" modified="2024-05-29" version="1">MDEFVDHLLRDDRYCDTILPRIPKRYVLEDLGELEPRVSKLEEELEDEDLMNDILENGNASEVEEEFNSLENEERNKKKTKEDEDDFKTKISKKKVNKLFKKDKFERMEEMNKKEREEDQLKLKKINKINSSGGDGDDSLSIEETNKIRLSLGLKPLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9B6</accession>
    <name>A0AAD5U9B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006913</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000063">
        <property type="protein sequence ID" value="KAJ3225372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9B6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="ASHA1/2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="264" mass="30217" checksum="D880795772A99EE3" modified="2024-05-29" version="1">MSRNVNNWAKDYFRDSLVGISYESSLNGVKVEIEKLSDFTGTKGDTTATGRIKVPEYMHDTELDEIVFEVSVDNETKEKEEIKKVLRSELIKLLREKFAPFQKDLIKHHKADVFLEVFDDKIPGQTKEKYQPKPPAPLLSDNFANKNQVVGGVTKIELDVEFVCSTSDLYSTFLDQKKVQIWTRGGAKVATKVGDEFSFFDDHYSTVTLLFDDKGDATILKLTQTDVPIGEKEIVRNNWHQYYMNPIKSLFGYGANFQVILFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9J3</accession>
    <name>A0AAD5U9J3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000059">
        <property type="protein sequence ID" value="KAJ3225509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9J3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="192" mass="22034" checksum="D97D6AE9E13C13B7" modified="2024-05-29" version="1">MITPSQLTFDKPSDDENDVSFEDTNDREVLSEDESDDEVSDNEVSDIRKEVQHIRSIPTEALRLVNYIQNFLFTKIEFSSGQAILLQDADLDAEDEEDDDYRDDMEENEDDSSCDSSEEMALEEELTDDELVEVVKGATHILSTESEEFLDENRLRGGKIIQNKNTSEKVVEVGKKIKEMMLSDEFEEDEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9W5</accession>
    <name>A0AAD5U9W5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9W5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="235" mass="26977" checksum="9856550AA631863A" modified="2024-05-29" version="1">MPVLENPWNSGSFSDSNDALVINFAPRKSSLVNPNIHIFQDDIQVATDSDYLDNDEFNDSSFKNDNLNLFNSNFFSFKSKHNNSNIDNSTTPTYFSSDTLNDEWKRDDNVSNYNNNYLKEDFITDTGSYGKKNFSNVKSNSSETLVFEELDNHFKKIEDTSLRDVCEEKHSLKISTGDPEKDSLISQTLYIQDTLKALLQKVVNCEKLYLQQENENDVLGSYVENLLVITNQKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAC3</accession>
    <name>A0AAD5UAC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005503</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAC3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00157">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="225" mass="25975" checksum="5F3BEF8A743C2054" modified="2024-05-29" version="1">MMTADEDAPYSLSKSRSSSKTLTRKGTISSIKNKLKKFEDGSCAIRRKLVCVGDGCVGKTSFLTRYSTQEFITDYIPTMYNNFKTPLTKYKINEYRFENYITEVEVDDKLVHLALWDTAGQEEYNRLRPLSYPGTDCILLCFAIDNVDSFKNIESKWMPEITHHCPNIAVILVGLKADLRGRFIKILEFLTYKQLYKTTSHFQEDAYLQVKESNFPILLELKSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAW5</accession>
    <name>A0AAD5UAW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">K(+)/H(+) antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">KHA1_1</name>
        <name evidence="9" type="ORF">HK099_003624</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3227001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="8">
        <location>
            <begin position="201"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="756" mass="82527" checksum="30C80010A0C10DDD" modified="2024-05-29" version="1">MVEAHAASTFLQGSNPLHDPFALFLVQIVVIIAFTRFIGFFLAFINQPRVIAEVLGGIILGQSALGRIPAFQNNLFPPESLSGLNMVANLGLVLFLFLVGLELDFGSMITNGRQATLISVAGIIFPFAFSTLASKVLYDTLMVGTTTPFGTFLFFNGVAMSITAFPVLARILSERKLITTEVGLITISAAAANDVVAWILLLIIVASISFFTQAVGVHAIFGAFLVGLMVPHDFGFAIKIAEKIEDIVSIVLLPLYFAYSGLNTRIDQLDSGIAWANVALVIFCACAGKIIGSFIACKVSGLPNRESLSVGVLMNTKGLVELIVLNIGLSAHVINESVFTVMVVMALATTFMTVPLITLTYPRSLHKFVGGPLTAPSHLSIESQDKKKLKIFLALRNMQSVRPMMSLLQMAPAGETNIELTAFRILPLGDRIGSLMKAQEASETLRADPVLEVFKTFAQLNHIPIDTMLSIAPQSEFAFNTIQAADESNVNLIIVSHRLPKFSRNEDSKIKLFFDDKYSNAALSRAIFAGAVNTTVAVFMDRGFNVGLDEQNFNIQDTVRSINSIRMRSVASPVLAKVFVPFYGGADDREAIIFCLHFYKGVDIKFLIMSSTKSHRALDLQESQAVLEKSETLEHVSIPAGEVNEDSEILETLRNHIDTLTNSQKFDEGSMVIEEVECEESERQFKTLSWLKDAALGSSDLVILGRALYEKARVNNTDASKFELEIPSSFFVIQHSSKAIEKGGNIATGNKVEKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBG6</accession>
    <name>A0AAD5UBG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBG6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="123" mass="13943" checksum="7C08A6765000F4F0" modified="2024-05-29" version="1">MEINLILVLIAIILVAVSCLVALTIYLVRSNKRLTDNFKKLEEQTQVKYSGEDQRISVAKPRKSSISGRLSFKEISLHDIDENSALEKEILHPKVVQSEANEQDDLLTEGPNYEISRNNSLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS80</accession>
    <name>A0AAD5XS80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001577">
        <property type="protein sequence ID" value="KAJ3202394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS80"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3202394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="398" mass="44150" checksum="2B58E41FCB10FF46" modified="2024-05-29" version="1" fragment="single">MTIVQSNFNRFNKRNHKRTEKWKILKQLKEELKKDFENDIEELINGSRRKDDDDDKDFHDHDGLSLEKLIPTLLDGERSSQGLPPPPPPPPSGKPEDGPPPFDKILFSPTTTLPESTIPPLETTEDIPTPQTSIIPPPLQIPGDMINSNVSGVVIPFSQQQTKKIVPLNPNDVDVNNSSSGFNKGGQNKLLQVNPLIAVAGSIFFCFVLVALTIGFKKRSKSNLLKGRRSENFDLFNSKRFNNKIADKETSQSRNSAPTTVPDDSMPPLKDIKGNSLTSSSAFSWNDLRASLTNVSDARGSFPTSISDIKRFSTLQKHRLTKKSNTTSTSSGFSWGEINRESMVKSDCDGAETANRILSQQSSEFSWGDENGFGTLDVEDTNNTVDMTVFIDINNNHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSC4</accession>
    <name>A0AAD5XSC4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001266">
        <property type="protein sequence ID" value="KAJ3204779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSC4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="200" mass="23426" checksum="065D42EF000EF0D1" modified="2024-05-29" version="1">MTVDIPTLTYFSSRGLCEPIRFVLSEARVNYKEVGVGAYNPNDQPKEFLELIESGKLPFNQLPIWEEPTGFVLSQSNAILRHLARKYKLYGDSIEENGLVDSIMDAIWDLKYLLRQQHLNEQDKVFEVTLPKYFKFFERILEKNRLIESLKVNDLNERFNFSQFPLLQKIYKSVSARPGILKHLESSTRYPAQVFFSPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT80</accession>
    <name>A0AAD5XT80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000900">
        <property type="protein sequence ID" value="KAJ3210248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT80"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3210248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="137" mass="15851" checksum="505B3103D4502E74" modified="2024-05-29" version="1">MSAPKYCPFDISRLSYQDKKDLYSLLGHDLKREKKIWVDINSSGGPLNVDNITKKFQSILMIKKDDLLPEKNSRLSGIVNDSAKAIQKRILEEQTQSTMTSEKRKEYNEIVASIEVNLGKKLEKYSLEDDDFEDYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTE2</accession>
    <name>A0AAD5XTE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL15_1</name>
        <name evidence="6" type="ORF">HK099_007871</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000801">
        <property type="protein sequence ID" value="KAJ3211996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTE2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="164"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3211996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="201" mass="23826" checksum="AEC1BE22BE249043" modified="2024-05-29" version="1" fragment="single">YKYLEELYKKKQSDVIRFILRMRCWEYRQLNVIHRASRPSRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPNPKGAVYGKPASQGITQLKFQRSHRSVAEERVGKKCGNLRVLSSYWVNQDSTFKFYEVILIDPQHKAIRRDPRINWICKNVQKHRELRGLTSAGKKNRGLGKGHKHNKVQGGGRHANWKSRNTLSLRRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTR9</accession>
    <name>A0AAD5XTR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynamin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000710">
        <property type="protein sequence ID" value="KAJ3213440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin N-terminal" evidence="1">
        <location>
            <begin position="105"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="180" mass="20511" checksum="9B8E312F7770263F" modified="2024-05-29" version="1">MSTEDWVKLNKYYDTSSDLTLSVSDLQTIQLNNVVTSVSDIQIPELNNTDYKPTTTYKALISEFYNDDISTLFNSLVEIKNKIHNIGKKSNNISSVELDIQLPRIAVVGNENCGKSSVLSRLCHLDIFPKNPSRCTILPLEFRLENKTEVELRKFYHDQFKCCPDNLDLSVAYIQVENGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUJ3</accession>
    <name>A0AAD5XUJ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c oxidase subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TTC6</name>
        <name evidence="4" type="ORF">HK099_005996</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000494">
        <property type="protein sequence ID" value="KAJ3216163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUJ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050498">
        <property type="entry name" value="Ycf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="150"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="246"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="503"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="671"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="705"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="739"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="773"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="843"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="877"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="911"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="945"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1021" mass="117139" checksum="99C51EEDE6A4EC29" modified="2024-05-29" version="1">MTKVELLRYPTFNDPTAMALAMVGTEAEEDLETEIKKMTSLIDDPFNTEVYWFRHQLLLRNKMAEEALKDLDTVTDSNRLHLGAFQAKAKIYQLLGLPKLAIVCYSQVIKLNPDDADPYLQRACQFEIENEMVYANEDYKMVRTLDPTNIRAITNLAIYSFERQLWDDAIQAFSKLINLHPNHGRACAFLARWDEALLDLTTAIQISPNRADFFVYRGCLLKERNIQKAIEDFSVSILIDDSNDNHNAYYQRALLYYKLEKYDFAVIDFKAAIEMNPKQSIGYLNLGLIYMQYLQDYKNAHDCFSKSILHGKGRSHLIYFLFHIQDAIQLRAYLCRGALYQKMFKENIPYHKLEVKDDAPVETDKPFNEIILNKNYKSNILIEKAVRDYSKCIHMSPGNYLVYLYRGKLLLKLHMMRESTYDFHAAFELNSGIAQTFVQRVLVLSFRKQFKQIIEEFNKLSAAEKNENPGLFLLVAKAKLKCSDYLGALSDLDSALELDPTDSQIYLQKGICYEQLKRFNDAVAAFSKSIQINAEFAKAYFHRGNCKLNDGNSSGVKDLDKALLLDPKFFEAHLSRAAYFHSRGKYVEGIEDCNKALKMEPSSIRAHLLRGSCKCKLNQFQLAISDFTKACNLDKNCYFAYYNRAVTYQLINDNLNAIKDYSIVLLLSEDSNTYRNRGLIYWKTGDTDNALLDLHSARDNFPEDANLHSLLALCLQKVGRMEEALESFTKAIQAMPLAIDAYLGRGNVYATMEKKDLAKRDYAKVLHMYPKCAEAYINIAYIFQSEEKFKKAWETFTAIITINPKCTAAYDGRAIVYYNSKNYFGALLDITKAIVTGTDPTNAELYTNKGVIFQALNDVSSALKCYKKAISLNKNYFLASFNAANSYFQYQRWDTALEFYNKTLQLSPCDVAALLNRAITKVMLKKDAEAMEDFNRAVELEPNSPQIYFNRAKLYFSLGRLQEAEADYSKVIKLSPSDAMAYLKRGETQKCQVKPLEAMKDFASWIATQDINNKALNEINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV09</accession>
    <name>A0AAD5XV09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000407">
        <property type="protein sequence ID" value="KAJ3217843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV09"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041987134" evidence="1">
        <location>
            <begin position="18"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="13504" checksum="79C0C7C7DC7012EA" modified="2024-05-29" version="1">MKFTTLISCSLIALATSQIAITRTDQAGNPQTTTIADNEPTLVIDGPNNSDAVGTGTETFVQESGSATLEVSGNSTALFNSTTTLSSAVTSLETSAILTTSTTAATAAATAKSSAMKSFNIGLGFALALAIYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVV8</accession>
    <name>A0AAD5XVV8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000274">
        <property type="protein sequence ID" value="KAJ3220775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVV8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="381" mass="43873" checksum="7D7E6A73D7636C4D" modified="2024-05-29" version="1">MKLEQNSSVATTDQTIINPDFSNFHQTTINFDNDDSLVIDEDSETKGVPYSQETIRRAHGCGQAYIKLAIEKKWKTGKNSNYFPLSLENLVVKRLSINFSEENLLMSPTTPNSNFLPSHNFIDVADPLHHNGIGNIGLKVNSANLKRALRVASTVTKVVLQNSWETEDKLFPIELHVLQKFTDSELKKVELGTMTISSFLKQLQYLDLYHKSLNLDWSSVRNDPSIIEKINLFFALSNSKIKKHDTDLNVYHLVKNDENTSLLQLNEKSDNLCINWNNNVNDLNHTNNYQNNGNHLDFQAPERQLLVYENKIEEGLKRKVIHNDINKITDSSKVLKNCNKFELEIKNKIEDNKKRKMEIILKMMEKGEDTRIIADILKFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVW4</accession>
    <name>A0AAD5XVW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CPR2_1</name>
        <name evidence="7" type="ORF">HK099_004054</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000278">
        <property type="protein sequence ID" value="KAJ3220728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVW4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000001">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041776960" description="Peptidyl-prolyl cis-trans isomerase" evidence="5">
        <location>
            <begin position="20"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="29"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3220728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="21592" checksum="1EFCB861747B2A52" modified="2024-05-29" version="1">MQFIKFFVALALMLTLAHAKGPEITHKVFFDVYQGDQNLGRMVFGLYGKTTPKTAENFRALATGEKGFGYAGSKFHRVIKNFMIQGGDFTRGDGTGGKSIYGERFNDENFELRHSKKGLLSMANAGKNTNGSQFFITTVLTPWLDGKHVVFGELLEGFDVLDKIENTPTKPGDKPKVDVVVKESGEISLSEKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWB7</accession>
    <name>A0AAD5XWB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003313</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000219">
        <property type="protein sequence ID" value="KAJ3221617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWB7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042023328" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="251" mass="27178" checksum="C07F138D11864326" modified="2024-05-29" version="1">MQLWSYLLVFSIFSTALGQNSTIPDTTTLPPTSSVVSTTTDATTTITTLPPTTQTSITLSSSITSSFSSSISNSQQSTATQSQTNKESTSLIPSTSSTAPPILANDNKASESTIIIVAVVIGVAIVVVVGIYIFRKAVVSKSTNFRNRMDPNRRLDNDSIAYGTNDYEGTSHFNNKNNNWIKLNDDVGRKVTVNTPSVTSHGLSNSSTIYSNTTHNMQPYGNGYSPNYTYPPNANNNHTTQQLPHNYVTYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWR4</accession>
    <name>A0AAD5XWR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ABCC1_2</name>
        <name evidence="12" type="ORF">HK099_002528</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000184">
        <property type="protein sequence ID" value="KAJ3222253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWR4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="108"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="456"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="623" mass="69655" checksum="1088E1F1FD11474A" modified="2024-05-29" version="1">MIDVKVREDDVKDVPKVSRNCDKPNPFDRTNIFQKITYSYIFPLFRIGYKNSLTNENLYPIPHSLSTSVSLDNFEKIWSEELKLKTDTYTPSLTKVILRLVRKDLIKAGIFFFFFSLASFVNPFLLSQLLLYISNSQNPLIETTLAQGLVWAFLMFLVEIVAAVSFPYYFNICGIAAIRTEIALQAFIFRKTVKLSTASRHIYNPGKVINLVSTDAGRISKFVKDVNFFWSVPFRVIMITIVLVIQIGTSALVGVGLLLVLLPLQGYLFKLYENIREAIAPITDRRVKTMQEIVSGIRVIKFYSWETSFLKKVTDIRNLELSQIYRKNILSAFLFSVLICVPMLCSSISFIIYGLTEALRAEKIFPSLTLFANLRFPLMDLPETIISYASFKVGIRRISELLLAEEMDETANNLIKESTETLVSDFAIELNNADYSWVLPKSDLNSVDTKNGDSSVSDYDGVEAGESGTVFGLKSISIRIPHGSLVAVVGKVGSGKSSLLNALLGEMKKTSGSAILNGTLGYAPQQPWVQNASLKNNIIFHSTYEKDRYVSAIRVCSLEADIRGFEDGDQTELGEMGINLSGGQKQRVNLARCVYYNSDIVLMDDPLSAVDGNTSLIVNGFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWY8</accession>
    <name>A0AAD5XWY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TRAF3-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TRAF3IP1</name>
        <name evidence="4" type="ORF">HK099_001503</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001426">
        <property type="protein sequence ID" value="KAJ3203462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWY8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070507">
        <property type="term" value="P:regulation of microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.50">
        <property type="entry name" value="Microtubule-binding protein MIP-T3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018799">
        <property type="entry name" value="TRAF3IP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041476">
        <property type="entry name" value="TRAF3IP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042576">
        <property type="entry name" value="TRAF3IP1_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31363">
        <property type="entry name" value="TRAF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31363:SF0">
        <property type="entry name" value="TRAF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17749">
        <property type="entry name" value="MIP-T3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAF3-interacting protein 1 C-terminal" evidence="3">
        <location>
            <begin position="248"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3203462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="403" mass="45949" checksum="81A9FE5277AF431F" modified="2024-05-29" version="1" fragment="single">GLEPEETNSFLQLLAKAVLKKVDPTSAVKKVLAGEHHGKKNRSKDSLAKASSSSLSKEKKESQPPVKESAPKQQQQQQQQQQVVTEQKPNLPNQKDLDSQYQKEQTQKDSKQKEKLKDQTLSNKSDQNKRSSSQPSQQDAEVSEENFKNNISSKDLLEQENKPILQQKEDGQQEKAQTIQGGLKKQMQRPASARPPPPKIRANKVVVEEQAVAAPIVFQENNQDKKEEEEDDFIVVNNDIQNEKLTIEENEKHGGLVRKILENKKDLEGNNAEKLAENNEKNSKIPKDKLTAKKEIDSLRDSIQMLCRSTNPLGKTLDYIQEDVDGMNKELNFWINEGKKWNERLEEEIKITNEEVEPIEIHLKNVEEKIADQLKVISVSKGLMLQNEISIQKLMRNIIHPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXP1</accession>
    <name>A0AAD5XXP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cilia- and flagella-associated protein 206</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_008709</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CFAP206 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000099">
        <property type="protein sequence ID" value="KAJ3224253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXP1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003356">
        <property type="term" value="P:regulation of cilium beat frequency"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021897">
        <property type="entry name" value="FAP206"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21442">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21442:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12018">
        <property type="entry name" value="FAP206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="696" mass="78756" checksum="9F15F4C4B2A7CA12" modified="2024-05-29" version="1">MNSAKEQRDYSDDKIALEHVISDIVSKANNELKAIKLSSTLNSIVKLESSLTNHPPKDSNIPISITEDETKKIENQQTDDKQDSQQQHISTLHSTTQNLKSRVSPYAVTDTLAAFVLRSVALDPQNKFDVDMEFEPNEVNRLINTCVEKIVQTNSPQMETVKMQVYFDTHFPAQADFLQKEKMSRTQACSVVLKEITDIKTKSVSIYESLYRKVASYVLIKSHVGNPTDIRIIREGTAALESVFPQSELSTFIPLTRVEKEEQLNGLTQLVTGIRLFNKQLGKGGESIDNLPELCASELQDLTTTVGQLTTETETFIQVYSGAIDYLTKFPEEQFEEVSLPNIKSALAFRRQLLMYLDALQDQMIRSRSTLLTLSNKFDSSVQELKTICRAKTAVAVDQVYPHFLLLSSLWINWLDELFLLSFRRGLIDVLEFHSKSFEALIPEKLKVASSSFLKDVEPVNLSEQEIIAAASELMVAVTSINRGVDIIHPGNITNYFNIPVEYGGFCPVTLLFRDGLVVPGNKNIGLLRYKDSVFCFAGIREAKEFAKTPEKFIEGVVIKAKFNPDLVQLLHLYQYFPTVDALEKARSFTRQKLLGKLPMVSEVGTQVDTHIVDGYIDPKYKWNEWELRRSALLLVNLKNKRTHGAQTDLSHFKRDITQTSTESSTSVPRRVNFHRGLRNDGKNVKFKVVDLTLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY04</accession>
    <name>A0AAD5XY04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RAD50-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RINT1</name>
        <name evidence="1" type="ORF">HK099_007093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000066">
        <property type="protein sequence ID" value="KAJ3225267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY04"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060628">
        <property type="term" value="P:regulation of ER to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007528">
        <property type="entry name" value="RINT1_Tip20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520:SF0">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1 RINT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04437">
        <property type="entry name" value="RINT1_TIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51386">
        <property type="entry name" value="RINT1_TIP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="427" mass="49488" checksum="8491E202BA7123C8" modified="2024-05-29" version="1">MDTHYTSTKLKNSLSEFISLQDLNEIDIKNVSLMMNGKIKKKMILQESILRKSTLAKNDALKTKISLKVLKDEYFSVTQLLQDTFTSEIIDTLKILTVKDQQLENFTLANLYLEVLAAVTRIIENIAKSVDVPRTAIPFLKELISFKEQGYRTLIGKQHDFDIKTELQLTNYINLKIKSFQEVLESNLSLKFEMILTELGWPNALTVKKMEQNYKEFRSIVSDLVLLPSNAGEKRTHLLFTILSKKQLVRLKYHFSGDRPTNRIDKPDWLFSYIKNIVREQSEFIHAILQPLLDELGISINGKFCQNLFETLKFDVSLAEEFEIDDGATFKNYVFERVFLNMNGCKETRSGESALDINYFHTWLDYEKNFNLSILQEISKKEDFSLVFGGMVDIASFDEFRLTRMGSDFITLLESITGDFFKSRHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY52</accession>
    <name>A0AAD5XY52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HBS1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HBS1L_2</name>
        <name evidence="5" type="ORF">HK099_006526</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY52"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16267">
        <property type="entry name" value="HBS1-like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="698"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="607"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="607"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="622"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="986" mass="108930" checksum="E48A1731C1D56ADD" modified="2024-05-29" version="1">MTEETISLINQIFKVKEVVGKILSDQTIQMALKEFEYDVEKATQINNTANEDNCASLNAEIVNEYSFTHSPAYCILKISNLSSNLPIQNNKKRLHHAYTKNELVPKCKKIERKKEITNAAADNEKVDFTLKLNPASREPVYPESSLNVISESIRNSNVPLNSPLPNVDLGSVPSSKINCNSTTSNNISPEINLSIPLSASATLSDIRTSKFDSGLGSRSGLGIDIAQNDESVLPIFGLENLSSAFSLPSAGLSNKLLLNLELPTGLGNLSVNNSSTLGFGFNDVSSTSSLSTSKIEPFEFGLGKLLSTKPLCEFQDGNLLPGKLSSGFQLDSLSSALPLLSETEPTMSQVVDSETATCEGSGGLSAKPQVMVPGLGSLYHQNESLHQQQISENNNSTLDKFSSFVENVNSLNVKLINNSLGSKFSETSLVKNSAVENKLDTLPLLKTFTDFADFCFSHNFSFIFASPVKFSLKNDFSLNSDDLTGEVNFLKEERNITKLKVLGLTKFSKEWNNKIEFLPNVTKHNFKKEIKGVTNDSNAPNSDNFKTKNFSSLEHTVLKAFQFDLPSPDVTAQLKSAIPFRDLGVKKIDNLAVKSEMLNNNLNKSTTVDSKVVKHSTSTHNESSKKKEELKSKTNKERKAIVTSDDSTVKISKCAKKNKEEASVPSPNRLKTFKKLINVEQEIEKLKATGEKAGINLVVVGHGKNSTKMEREYGFTVHYTTTSFQTEKLKVTVFDTPGYQDFTQDVICALSQACLFGDVALLVVDSYNEDAAVPFTLNRQTKEPWSQKKFEDVKDSVASFLVTAGFPRHLIYFIPISGFLGENLVEAKNPLLKSWYSGPTLHQQINQLKAPNRLIQNKFRMSITDIYKISSSNTAKVCGKILTGIVQSGDTVLIQPADFRIIVKAIEVEAEDTKWAAAGDVVTLSFINCDLDLFSYYFRYIVNLKFIFRIGNILCDPMVPLPVTFHFKARIVTFDLKHPLIGDHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYP9</accession>
    <name>A0AAD5XYP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYP9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="213" mass="23689" checksum="413850DF966864AB" modified="2024-05-29" version="1">MIVPSTTTINLTTTSAQAITNVSDAVKSSSSSDSVVQFTQVAFIASVIGGALILFVVLFCGFKYYKKKKNQKEVDLYPFLQNRRHFSERFPSTDDRLQKKNEEKMDMDQVVVEQKNYTDTPQAVSRPMTENLALRKNLTLSQFETHKNWLKLSNSSNHNDGLSENSGSSFQQDIQANATSSQHSSSSGNVQVHGDGNNLSRSPVKSKFKKTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYV1</accession>
    <name>A0AAD5XYV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Biotin-protein ligase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000226">
        <property type="protein sequence ID" value="KAJ3221511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYV1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019197">
        <property type="entry name" value="Biotin-prot_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09825">
        <property type="entry name" value="BPL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin-protein ligase N-terminal" evidence="1">
        <location>
            <begin position="50"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="250" mass="28162" checksum="B6B71463FD7E3C78" modified="2024-05-29" version="1" fragment="single">ISQWFPPPFTPPSSLSNLQYGSSLCPEQNFRKTALIFLRKRCDEAESACSEDIGRMLQSDGWSVKYCGIGEIEKNLVLSEVQLYVQPGGNMDVDKLFRKLTDSDIASIRNFVSCGGRYLGICLGAYLTGPKCLNLTEKSSPYSSKKGKYKPLLSEVIFENQTRLIYTEEPPELGTQQDIPGKLKILSRYTKDQTVQILIRKYNNGRVCLMGGHPEAMENWGNKHAKVVDKMAWDIGCKTVRQLCDDNFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ90</accession>
    <name>A0AAD5XZ90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GHMP kinase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ90"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047940">
        <property type="term" value="F:glucuronokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053034">
        <property type="entry name" value="Glucuronokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38710">
        <property type="entry name" value="WITH PUTATIVE URIDYL PYROPHOSPHORYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38710:SF1">
        <property type="entry name" value="WITH PUTATIVE URIDYL PYROPHOSPHORYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="3">
        <location>
            <begin position="183"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="414" mass="46908" checksum="DEF3DCD12C1A2627" modified="2024-05-29" version="1">MREPVINYFKQKSLEFNTKKVENVNEYKHFLKFLFHKTTVQPIKPPKGIVWDWLKLNLSAEKYLSIYQNLTWSKANFSETESFKTGKRSVAKVYARVGLLGNPSDGFFGKTLSMLISNFWAQVSLFPNETEDIIFLSNSLLDPTKFSSIHGISGVVNKDGYSGALILFFAMTKIFTNYCKNNSISLKKCGFKVIYETNIPRQVGLAGSSALIIAFLKALLKFYEIDDSVIPLHVQANLALNAEKLELSISSGHQDRVIQTYGGVVYMDFRESLMKERGWGEYEKLEDNVSFEVFDGLWLAYVGQPKNSGLVHNKVRSKFENGDKEVIAAMEEFGSFAKGGLQALKNRNRKEFALLMEKNFNLRRKIYGDDVIGERSLKMIEIGKKYGFAVKFSGSGGACIGLWKGINNMQFVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZI9</accession>
    <name>A0AAD5XZI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome control protein 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000158">
        <property type="protein sequence ID" value="KAJ3222809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZI9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034066">
        <property type="term" value="C:Ric1-Rgp1 guanyl-nucleotide exchange factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040096">
        <property type="entry name" value="Ric1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746:SF10">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746">
        <property type="entry name" value="RAB6A-GEF COMPLEX PARTNER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25440">
        <property type="entry name" value="Beta-prop_RIC1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1153" mass="130860" checksum="F248E09DCF13EEA2" modified="2024-05-29" version="1">MFFATGSTKILSAQNADVSVDYQTSPLNPVNPETRTLLNLISIKRSRHGDLFASITYNSLYLWSCRVSTVDAFMKILIFLRQPDVMIGKITRSQVTVEEDGENVEILWKPDSTAIVVTTNKGYLHFYDILNGEGKLFDFKFINPHHYVIGAGEKGGCPNKSLRFKMAIQIDTGIASAIGLSDEILICTSESPSLLSLCWNGEVNASGTCSLADVSFLTNPADPFVHMTTNKFLDLFCWTSKFRNCYLAQRKLVQKLDNNGDANAPQELNCVWVWSGLCFFNSAKTKNNAVTCAINSKLLKLAVGTHDGDILLFSLSEDKTSLSYMHTLSLSQPPGLSNVFHVGPVSCLEFSSDGNAIAVGWHFGGLSLWSVAGRLLFSTMSEDTIAESPTERPTISQEDYFNGVAHLFFGPGSYDLFILPSQSYSNDVVNDIYVIPFAKSALTMSKNSDNTRCICLVSDDKLLLHEANIGDSFGYLDSNLVLWDSIQIPVMYLGENWPIRHCSVNSTGHFAAIAGKRGLAHYSAKTNKWKLFGNEHQEQTFFVTGGILWFKNILIFACQDLETYNHEIRFFSRDNNLDNNLALHVEKMPRVVVTMNILANNILVYTADNVLRYYVIKFQDQKMKLLLQQQLSLTNMVTLPQYVNSVCWFPPPSPKINSKVLKKSPILFLRNGILSLIIEKEKGEWEHIILSDRIEFFWLSNNEERISDLYNSLWAFDGFGVKIWTNLIVSDEVLNSRMQQEASGFANKYQSLDYFSHSLELLLHQVLEEESDTQKLNLLPVVTEFIQTNFTKNYFDIIIRCARKNEPSIWNFFFSCVGDIKLIFRQCLDLGLLNTATSSLKIIQILETESVSGKFATELLDKALYMEEFEISREVIRYLSTIEDRLPYTDLIQKETNFEKSDSATPIDVVSKPAINTTFYLEVLISNHARKMVERDRWRALGIFSNSLSFPIVPWLRNESPKVSLPWSTILSKLHLQFNLPLQNDYTVIYNCMKQALTPSGFAIKRRETVSFISPRESEVNRRTNNNNSGLKIVIDQSSRKPFKSKSFATFESDTDSSFSNTLESNSYFKSNVKSLLEIRQLFKYMEESGLIEMGIIFGIMIMEIEWICCKLHDDTSETKSLMKKFVEVTKNSECQAYRQLHNLVINIIAEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZZ1</accession>
    <name>A0AAD5XZZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutaminase</fullName>
            <ecNumber evidence="3">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003907</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000263">
        <property type="protein sequence ID" value="KAJ3220922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZZ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006543">
        <property type="term" value="P:L-glutamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.710.10:FF:000005">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00313">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015868">
        <property type="entry name" value="Glutaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03814">
        <property type="entry name" value="Gln_ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544">
        <property type="entry name" value="GLUTAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544:SF29">
        <property type="entry name" value="GLUTAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04960">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="624"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="648"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3220922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="678" mass="76732" checksum="FFB1137B3E338C27" modified="2024-05-29" version="1">MDKCSFSHELETCDVAEKYSVCYNFFKSHLKNDQNLCNLHEFAIVLEKWGFLKDDPRFQKLYKELMKNDHQYKTVDFKEWLSILTKSQVFVILTKAFSLKLVVQDFENFTSEIIKIFEECKKETNLGGANASYIPQLSKVDPNLFGLSICTLDGQRFLLGDFEKSFSIQSCIKPLIYCMALEENGEQFIKNHIGREPSGVAFNSLTLNRENLPHNPMINSGAIMSCSLIKRNLCTSERFEHINQILRKLSGDKQWGFNNAIFLSEKETADNNFCLGYMMRKNHCFPEKTNLMDVLDLYFMCCSIETDCNKLAIVGATLANGGVCPLTGEQIFSRETTRDCISLMYSCGMYDYSGEWAFTIGIPAKSSVSGGIYTVIPNFGSISLFSPAINDTGNSVKGVQFFKKFIQKFTLHNFDKCDGLLTLGDQRINPFKNQVVSEREMKVAAFYAASEGDLFELKRLLTLLPINPAKVVDYDKRTLLHVAATEGHILVCKYLLKHHNCDMHVLDKWGGSPESNAKRFEHNEIVELFKNWKNNNFQAVESEFSSSPTINKTFSFSEKMKKSYSQQELQANNAVNFKLPDIGYKVTDLHIDVDNRRALAISFYNAIGTSRVFSGIFAKVFGRLNTYVLDTFVAGTLILTLLSLSESFIILIIFTILYGLLGGGIESLLAVVILDILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0A5</accession>
    <name>A0AAD5Y0A5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000226">
        <property type="protein sequence ID" value="KAJ3221510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0A5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="1">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="112" mass="13416" checksum="EE4791F15392749C" modified="2024-05-29" version="1">MQLDVSRSCQIYRKALKIIRYYPLKVHRFKLAYNTREIIEAYKNETDENFLNELFKRGERDLKVLNAFSLLKNDKDLFKLMKELALFNPNSEHKGWLPTFKGNATVMKSRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0H2</accession>
    <name>A0AAD5Y0H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000079">
        <property type="protein sequence ID" value="KAJ3224840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0H2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="264" mass="31084" checksum="7D120F8AE93133D8" modified="2024-05-29" version="1">MILIGIQLLQITSFILQFRNYKIEDENAKYKINTSDVRYSFFRDDYNFFLTNIIGIIMWFTFVAVIYMDVDRFVKMEMILINSFKHKLINIVRIFSIILTMAYIIFEIVDSSTNRYIRLSEHVFLEKEPSRENFHLAYNMFGVAMTFWFSGLDLYFGVKMVKMVILSKRSERKDKWVYIVLLALVTLMDVAAAVLLMFQLNKAMNHIAVSFVACHYQFSNILLILIGSFTKQNRRKKCKLRNPSIVTQLSDVSYHEEAPESLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0W7</accession>
    <name>A0AAD5Y0W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar protein sorting-associated protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VPS11_1</name>
        <name evidence="10" type="ORF">HK099_003478</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000228">
        <property type="protein sequence ID" value="KAJ3221468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0W7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16688">
        <property type="entry name" value="RING-H2_Vps11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057308">
        <property type="entry name" value="CHCR_PEP5_VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024763">
        <property type="entry name" value="VPS11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF24">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23356">
        <property type="entry name" value="TPR_PEP5_VPS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12451">
        <property type="entry name" value="VPS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17122">
        <property type="entry name" value="zf-C3H2C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="236"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="323" mass="38248" checksum="57E70A7DA9D17C8A" modified="2024-05-29" version="1">MPYTENALESEQQNLSIKSKASLNVICDTLIELYLGKNNKYEKENDDSHLKYENYALDLFKHSLTIFDYEKSLVLCKLRKFDDGVNYLFLKLKLYKEVIQFHVEKKNFDMLIKFCKEQNNPELWIEAINCFSEITNFSDDGKNLELNNLNFALKEILSQIEELNLLTPLQVLKILSKNECITIGMIKDYIIRRVENDKQILEDDQKLIKSYQEETLKIKQSLLDLKRPVIFQVSKCDLCERPLDIPTVHFMCKHSFHQRCMQEDIKECPICGPEQSIIRDLIKSQKENANNHELYLTTLESKRVDERFNYISEMFSKNVFRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y125</accession>
    <name>A0AAD5Y125_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the NRARP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000209">
        <property type="protein sequence ID" value="KAJ3221778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y125"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004857">
        <property type="term" value="F:enzyme inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019208">
        <property type="term" value="F:phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051226">
        <property type="entry name" value="PP1_Regulatory_Subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24179:SF21">
        <property type="entry name" value="MYOSIN BINDING SUBUNIT, ISOFORM O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24179">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="315" mass="36038" checksum="A0AA41F89F842C81" modified="2024-05-29" version="1">MAVGEIPKFLISKNHEIEVLDSKYSGTPLAWACYCGNLELVKYLVELGANVNAKNSSGQIPMDLVDEEHMQYGEFYEKLTGNSKYTATKKKSDTEKKVEEVSPRKSDRRFKDSDESDGTVEGKWYNFHKIFEFLVDNFDEDNESEEISYPQETDHMVTRSSRREPKNLLNPDNISFISSVGMVSSKNIIRKVIDPSHFKHHSLQIHPSVRTLAIRVILKDFNLEKFPFLNLKVFWNQKLLEEKKKNINNSAKKNNNTISNSNILGKFGYTIDFQISQLFFGINKIEVQINGHSTGLRSTGTNAVLESVVIFLIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1C3</accession>
    <name>A0AAD5Y1C3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004177</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1C3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="2">
        <location>
            <begin position="165"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="362" mass="42799" checksum="6F182B611D1A5668" modified="2024-05-29" version="1">MKLLLILTGVVTCMGISFIKFRYNLTKEIKKLRLELKKEQQKNSVILKNRDVFKTLNDKLLQSLSVEKDTRFFVEQLLNEKIKKLELSLDFKDEEVETLKSELTDAKEDSSWETNNIPCNNIYQFTFNEDELEQYLTKNSSLSNEYIEEETENVNEIDSGCETIEEDESKIHENAVELVLQQIISNSCAESVLQDLENYNFKYLFNFNVKLNKLNVIVEALFKYFNLKNILDSEKKILQVFEKYNSAISKYVLSEKDQLQYLRLIEKLSITHDTHHRHHLKILKVQYRLELIEFNSLSLWFNQKSNDADSIQIRMLCKPFVDWLTSQFEKDTDDEEEGDSFDEYDVSDNIRSKILKSVTFQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1G8</accession>
    <name>A0AAD5Y1G8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1G8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000286">
        <property type="entry name" value="PH-protein kinase domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336:SF8">
        <property type="entry name" value="PROTEIN OPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="38"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="278"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="452" mass="52035" checksum="157DB09AABD309F5" modified="2024-05-29" version="1">MSQSNSASGSRDSLRVRINAPFSNKEILQSISPLHSEKNLKSGYLKKKGNSRKSWKKRWFVLRPTKLCYYNDEKEYELLTIINLNEIHTIAMVNYNSHREFVFALVSPNRTFYMQAETKESLVDWVATIKAVKKDGFDMANGTVSMDPKNLKRLISIQLSEMEATDDTSQISNPSTIESQLTVLSNTPSNSNLNNNRRGSHPLSQSSINRVSSPESSSADSDSSEHLVDDEEDEEEEEEEERLPNVGVMTHRGDLLVSSNSLNLERELTDNGVFYEDKILLQGYMKKRSKNFKNWKTFWFVLRNKTIYMYKNEKEYILLKIIKLNFASSQNLTNDKKLNKKLIIDIINCNSKPEDSNKKQRDLSSDNKTTNNHHCFKIVFLKKEMLFSCETEKMRDDWVTKLKEILEESKTIGSNSMGSRFNSNGNLINNTGRSGSHHYIVDRSDEGWIEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1N7</accession>
    <name>A0AAD5Y1N7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydrolase 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1N7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="145"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="638" mass="71985" checksum="9DA9B93C00856F07" modified="2024-05-29" version="1">MSHYPGESQPLLPQYSEALLVNQQPANVITLPYGQRIVSSQPQPQIVVIERPVLYQQPVIVRHINRYDDDCDCCCACAITTYTPKLQIPLNYDNGALSKIYFNATVYTVDKMNPVVDSFGVKDGKFFSVGKFRDAEELFKGVNVEFINLNQKTVIPGLTDSHGHLMNLGRMLSNAQLQATRSIQEIRETLLEFVAKNPLKSNEWLIGRGWDQNKWNEASFPTFKDLEHPILSKFHILLTRVDGHAVWVNKKVLDFAKIPAEDPLGGSIVRFSNGLPTGVFIDNAQNLVTSLEPEASEEKLNKILDLAIKEMLSKGLVGVHDAGVTKQELKLYQKAIDENRFPIRNYAMFSSENLVDKNLKKIKNYKNKLVMTSVKVYADGALGSYGSAMDKPYSDDPSKIGFLLSDEKEFYNIVKEYVKLGFQVNTHCIGDRGNRVILDAYEKVIKDLNVTDNSDLRLRIEHAQIVSLSDIKRFGKLKIIPSMQPTHATSDMYFAEKRIGKERIKGAYAWKSMLNAGVSALPLGSDFPVEAVNPFFGFYAAVSRKDNSGNWPRKENVNEISKENGGWYPNEKLTRMETLRGFTIDAAYASFREDVMGSIEEGKFADFIVLDRDIMKVEEIDILGTKVLNVFIDGKKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3H0</accession>
    <name>A0AAD5Y3H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-phosphofructokinase</fullName>
            <ecNumber evidence="4">2.7.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PFK1</name>
        <name evidence="16" type="ORF">HK099_000776</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3H0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005945">
        <property type="term" value="C:6-phosphofructokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070095">
        <property type="term" value="F:fructose-6-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000007">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009161">
        <property type="entry name" value="6-Pfructokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02478">
        <property type="entry name" value="6PF1K_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697:SF4">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="15">
        <location>
            <begin position="166"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="15">
        <location>
            <begin position="561"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3227672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="751" mass="82147" checksum="E2E169ABCAE15331" modified="2024-05-29" version="1">MVEINLLSENSEEFSQLINFYLAIGFKKLNQVENQVKVHFFEKLSGLTLNLVLKSNEKYDFDSKNLKSQINQKLNNTTPSKVSFLSLNSSSKVVLETLKKFQYPFKIEENLNEFYSYDPLLNLIKIKLSNQNDEKESSKNEIFLNKSNPKKEDAIVSDLKSATRKRVGILTSGGDSSGMNAAVRAITRYSIYKNCIPYAIFDGYDGLVEGGSKIREYGWENVRGFLAVGGTSIGSARCLIFREREGRLKAAYNLIKNGIDALIIIGGDGSLTGANILRTEWKGLLDELVQKGKLQESECSVLRNNLTIVGLVGSIDNDMSLTDITIGAYTSLHRICESLDSLTSTALSHQRAFVVEVMGRHCGWLALMAAIAVGADWVFLPERPPPTVESTFEDWETEMCNRLLEQRKLGSKKTLVIVCEGAIDRHLKPIKPEYIKQVIDKRCGLDTRVTTLGHVQRGGTPCAFDRILATLQGVQSVEAVLKSTPDTPAPMIGMSQNKITSVPLMKAVELTHAVGKAISEKNFKLAMELRDPDFNAVYDAYVEATLLTTSPVNGGEKKGLRIGFINIGAPAGGMNAAIRVAARLCLNRGNLPIGIRNGFSGLIKDEVAPLSWDEVSGTQVMGGTILGTNRDHPKPLDNNMVLTGVSDFVDIGLIAFQLQKHKIDALLIIGGFEAFTSTLTLCRGRKAYPAFCIPIVTLPATVSNNVPGTDYSIGSDTALNAIVDSCDRIKLSANASRNRVFVVEVQGGNCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSN8</accession>
    <name>A0AAD5TSN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Xylose isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002025">
        <property type="protein sequence ID" value="KAJ3199839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSN8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3199839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12633" checksum="B14E530B4A465509" modified="2024-05-29" version="1" fragment="single">AATLIRSWDTSDDTNIGFEKILQNCKDRVDAAFEFFVKLGVDYYCFHDRDVAPELLSSRNFLNDLKFLDLPEKANTRIKKADKLIGKQKYSSAVIKICKVLMVIPEELQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSP9</accession>
    <name>A0AAD5TSP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003488</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002282">
        <property type="protein sequence ID" value="KAJ3198715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSP9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053238">
        <property type="entry name" value="RING-H2_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14155:SF627">
        <property type="entry name" value="OS06G0192800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14155">
        <property type="entry name" value="RING FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="30"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3198715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="84" mass="9901" checksum="EF037A2EFC9D5786" modified="2024-05-29" version="1" fragment="single">EMEQLKTFHYKKNELSSNIDNNERIEQHSCVICLESFNEGDSIRELKVCTHIFHKDCIDEWFSSKFNLNKRSCPLCSCDALNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT83</accession>
    <name>A0AAD5TT83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001705">
        <property type="protein sequence ID" value="KAJ3201580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT83"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3201580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="333" mass="37861" checksum="E52395925B340C41" modified="2024-05-29" version="1" fragment="single">IEQSQRLALKFKALSLFFVSNNGNEGIEMLKSRLFNLGKEEKFDYTMSDLNFTLEDLDKKNEMEKKEKLNLLQMQLQLENEEKLRISIEERRSFEERRREIQKDFDKISLNTTLTQLTADEVNEIDKDNVSSENIEDNSKKSFLEETDISPISTKTVEIDASVKSNVNLNETGNQPISTENIEMDILTKSNTDHKETEGNIIVDSNISKISNTSELLNNEKKKEESEKKLSSETLTTISNLAPSPSMSKSSLSCSSSIDGKKKKNSRISFALQDDVVFVPTNKKILKKNSITSHSQTSHSQTSHTTKVFVPRLSKEFTEKLMENEPGKCCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTX6</accession>
    <name>A0AAD5TTX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001475">
        <property type="protein sequence ID" value="KAJ3203112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTX6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="11425" checksum="472DFD8908096F99" modified="2024-05-29" version="1" fragment="single">MIGALNKLPVTILGLVLFEDQVTLPGICGIILAFFAGLIYTFAKNAEAATQQDLLTNLSFSKTFNYKKVELNNLLVKNDFKININSDKISDGKFGEKFVGFTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUT8</accession>
    <name>A0AAD5TUT8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tubulin beta-1 chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Beta-1-tubulin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_000302</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001063">
        <property type="protein sequence ID" value="KAJ3207316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUT8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000009">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="16">
        <location>
            <begin position="64"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="17">
        <location>
            <begin position="263"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="484"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="631"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="498"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="515"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00077944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3207316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="668" mass="74271" checksum="9F72CEAA42AD246C" modified="2024-05-29" version="1">MTREIIHIQTGQCGNQIGLKFWEVICGEHGIDPNGNYSTQENSDQKINSSWSKRTVKDLQLERINVYFNELRGGKYVPRGILVDLEPGTMDAINGGPYGKLFRPDNAVFGQNGAGNNWAKGYYTEGAELVETVLDITRKEAENCDCLQGFQMIHSLGGGTGSGMGSLIISKIREEYPDRMLCTFSVVPSPKVSDTVVEPYNATLSINQLVEHVDSTFCIDNEALYDICFRTLKVSTPTYGDLNHLISNVVSGITTCLRFPGQLNADLRKLTLNMVPFPRFAPLTSRSNVMYNNYSVLDLTNQLFSPTNVMAALDPRNGKYLTVATIFRGKLSMKEVETTVYNIQNKNSSNFVEWIPNNIKTAVCDIAPKGMTRSATFIGNTTSIQELFKRIHNQYTAMFKRKAFVHWYTGEGMEPMEFTEAESNMCDLISEYQQYQDATVDLNVDGEEEEESLDSRIKQNKKQQSTIEKKKEDRLFLKEREEQELKQKRENIQKSKIKSNADNRGNFNQLKVPKKATAAGSSSFSSSSAEKKPEVNNNQKAGVLNPVSKESKPVLPTKSLNQKVIVKPIGNSSTSEKNRSSSTLVKSTTTFNSVIEKSAIPKIKNSGMSSFNDMINKNPIIYDRIGTADSKISTPTSVKSSSSTVSLNKTLAKSTTTSKASLNSSFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUU7</accession>
    <name>A0AAD5TUU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002594</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001871">
        <property type="protein sequence ID" value="KAJ3200600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUU7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="6">
        <location>
            <begin position="8"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="49"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="232"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="349"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3200600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="375" mass="42144" checksum="833999FCBE0491EB" modified="2024-05-29" version="1" fragment="single">NGVDVTRRLSVESDPFTCYSPREYPGTIESTPLDKYFSEQGLKIRIRKETWNSRARTSNDAHFNENKRRRSEEDEPADVAPKNLKVYDSNGNLLTSPQEPSYHSWSNTPPSEPALSPLSMPRVDSRPTPPPPNPPSTYQHSTHQNTQGSAPLNPVTNHSRPPTQSPPLDKPPYPPASYQTVQSPQYRPEVNFPPYSNYRPVQIPPLPEYDIAAHPRPHSPVRYLAPIEAPRDYYQAPPSGYHHPPSQIPYQSDPRLRYQETAYRAPPGSRPYPPPDTYRGVRQPVGGAPSGYPHYAPQHHHPPPPFQHHPHSSLPPPQYQPHLSPHPGSNSHQQGPLSQHSHQGPPPNSHQSAPIHQNQQASQQNSPVGQPSQQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV00</accession>
    <name>A0AAD5TV00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002441</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001800">
        <property type="protein sequence ID" value="KAJ3200987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV00"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="164"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="64"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3200987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="465" mass="53142" checksum="66C4841D2F4D29BC" modified="2024-05-29" version="1" fragment="single">MSVINNNKLKDIKAHSVTISTKPISLTNNPCFPIKLNETDKKAQQIFFKQQLTSFIYQSQQGFTTSTSPKSVNTNSSLLSPPSPPHLIDTLNNKDISKSDPTTDSTNSPSSLPTPISPNSQLFSSVGLVESKVYVCDHENCDKTFVQLAHLRIHQRKHTGEKPFKCSFENCEKQFTQLGNLRTHERKHTGEKPFKCNFPGCNKSFSQMGITHQCKSHNRNPNSADISSEDEEEIIILDEPINSTSPLLPNNNNNNLKRERQEFEQQEEESSFIKTEKNEKVFEDEAPSFPISSTCSSPILPPQTTDATFNNQFSYDSPSPYYQQPLEKKIKISKEEKLLIKLKNVLNRNSYDDHSSSDEDDYDEETEDFNQEEENQFKFLCSVVEKEANEFEDLDLDEMDSDDDEDELLNSINNNQQQQNFDNNNSLLNQHHQNFLENIDNQEEDEEEIIDIVGGIDESPNFNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVA7</accession>
    <name>A0AAD5TVA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL32_1</name>
        <name evidence="4" type="ORF">HK099_000498</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001113">
        <property type="protein sequence ID" value="KAJ3206589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVA7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_eL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018263">
        <property type="entry name" value="Ribosomal_eL32_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_eL32_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="Ribosomal protein L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00580">
        <property type="entry name" value="RIBOSOMAL_L32E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3206589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="133" mass="15520" checksum="656CC7E2883F20F0" modified="2024-05-29" version="1">MATSLNKTPIVKKRTKKFVRHQSDRYDKVKESWRKPKGIDNRVRRRFKGQIAMPKIGYGSNSKTRHLLPNGFKKFLVSNVRDVDLLLMHNRVYSAEIAHNVSQRKRVEIVARAAELDVKLTNAHGRLRTKEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW36</accession>
    <name>A0AAD5TW36_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Regulator of chromosome condensation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RCC1</name>
        <name evidence="6" type="ORF">HK099_008138</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000863">
        <property type="protein sequence ID" value="KAJ3210970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW36"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="66"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="67"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="119"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="169"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="227"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="287"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="340"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="394"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3210970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="440" mass="47836" checksum="A8E94330521003A9" modified="2024-05-29" version="1">MPKVTTQISSPRQLRQRVEKPNTDTKQNINSKTEKKDKSVKSEKPHKMPRHVEGFPLPNLLNEEIGDVFVVGSGDCDQLGLGEDVREKEKFGKLAYFDDKDIVKVVAGGMHTVAISKQGKLYSWGCNDEKALGRAGEQDVPLPITALEHETIVQVCCGDNCTAALTADGRVYNWGSFRSSTGSFGIKGGIMEKDGIRVTNPLLVKDLNHIKFIAAGSNHLVAIGHDGKIYTWGIGEQGQLGRKILQRFEYNASLTPRVINFKPKGKSSKFIKAYAGSFHTFFVHESEEVYACGLDNYGQLGLAKTSYEVNHTPEKVEGDFNGVNFISAGEHHSLLLDNEGKIFSFGRGDSGQLGHDDEKDKNFPELLNNIPLASQITCGSNFSLAITADQSAGDNLYGWGYGEMGQLANGGQDETTPANIKVGGRVVIGITAGGQHTVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW72</accession>
    <name>A0AAD5TW72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4360 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000841">
        <property type="protein sequence ID" value="KAJ3211330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW72"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042166705" description="DUF4360 domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="21574" checksum="228E405CB17B0C81" modified="2024-05-29" version="1">MKLILVLLSIIVFVFAQAPSPNELSIAKITYGGSGCPQDSVTERLEEQNTKITLYFNEYSAKMGPGIPVVDSRKNCQITIQFDILNGGWQFSLSSANYSGNLKLSVGAVAQQSSAFYFEGSLNAGKKDKTFTAEQNGEYSVAKVFDDTTIWSECKRNTLLNLNSQVRISGPAGSSGEITSSLVSLKSTQSFGLIWRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW84</accession>
    <name>A0AAD5TW84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_008194</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000879">
        <property type="protein sequence ID" value="KAJ3210644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW84"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17955">
        <property type="entry name" value="DEADc_DDX49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="17"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="265"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3210644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="447" mass="50092" checksum="0203761E6B1B9FF8" modified="2024-05-29" version="1">MTELSIKFPTPIQVNCIPEILNGKDVIGSAKTGSGKTAAFALPILQKLSEDPFGIFAVVLTPTRELAFQIAEQFKVLGTGINLKQVVVVGGLDMMQQAIELSKKPHIIIATPGRFADHIKSSHEAVDLRRLRFLVLDEADRLLSESFEEDLECILDNLPTNKRQTLLFSATMTKEIEELKFGGNPPFVYSGNTRYDTVDKLDQRYLLIPFTVKDVYLVYCLKEKFGIEQVEKKSDNTIVNGHGKKSIVKKKKPNLKIQDENEENNIKSELNTSVEKKSLIIFGGKWKTCERLYLMLRELGFKCTALHSRLSQKERLASIAKFKGGIVPILITTDVGSRGLDIPTVSTVINYDLPADPTDYIHRIGRTARAGRGGVALSLITERDVEVLLNIEKSTKKKLIEFEGLIENEVLDLMNEVSVAKRVANLTLVDESKSKFGHKLRVYNNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWF0</accession>
    <name>A0AAD5TWF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPL19_1</name>
        <name evidence="7" type="ORF">HK099_000668</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001166">
        <property type="protein sequence ID" value="KAJ3205921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWF0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="6">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3205921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="215" mass="24769" checksum="0000006EC937D379" modified="2024-05-29" version="1" fragment="single">VNLTTQKRLAAAVMKCGKRKVWLDPNEINEIASANSRKNIRKLKKDGLIIKRQDKATSRFRVREKLAAKRKGRHMGIGNRHGSADARMPEQVLWMRRQRVLRRLLRKYRESGKIDKHLYHQLYLKSKGNVFKNKRVLMEYIHKAKAEKARSKTLADQAEAHRNKARAVRERRAARLQAKKDELFGVAETKPVETKAPATEAPAATTKSSKKTSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWP9</accession>
    <name>A0AAD5TWP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cupin type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_007806</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000796">
        <property type="protein sequence ID" value="KAJ3212080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWP9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042270293" description="Cupin type-1 domain-containing protein" evidence="7">
        <location>
            <begin position="18"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="8">
        <location>
            <begin position="38"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="212"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3212080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="312" mass="35583" checksum="06B5F756630F24A2" modified="2024-05-29" version="1">MKFLLVATLALLNTITSDPKAETTVQKLDKFKPEDFVIDLLNPAQPGIVSPMNLGNLPSLEGQGISLALINLPPCGLNAPHIHPRASEALFVIEGNDVQVGFIQENGAKLEVNTLKKGLATFFPQGSMHFQINNDCKPAVLIGGLNSEDPGVLTIVMNFYLLPSGVIEASLSPETDLLHEAKGHKNLGTAKGFTDECRKRCGLDVENKKEYKDMKEDKKEEKKEEKKEEKKDKKEVVDKWTQKGEDEDGEEGEEEDGQKFRQEAKYDDDSDHYKNHYKYKYHKHHNKYYQGSNYKKHRYHKNHRYYVNEEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWQ0</accession>
    <name>A0AAD5TWQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_007532</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000739">
        <property type="protein sequence ID" value="KAJ3213170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWQ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000110">
        <property type="entry name" value="Nuclear factor Y, subunit B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="8">
        <location>
            <begin position="23"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3213170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="176" mass="20897" checksum="88DBADE3CF629AA0" modified="2024-05-29" version="1">MSHSIKLVNNDDDFEELREQDRYLPIANVARIMKRALPENAKIAKEAKECVQECVSEFISFITSEASEKCINEKRKTINGEDVLWAMNNLAFDNYCETLRLYLHKYREATKVGTSQKDYEFEQQKLNHSHISHLQMLHQRQQLTQQQQIQLQHNQEIIQRQSLEQQQLQQGNQDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWS7</accession>
    <name>A0AAD5TWS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NPC2_2</name>
        <name evidence="10" type="ORF">HK099_007098</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000661">
        <property type="protein sequence ID" value="KAJ3213968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWS7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00917">
        <property type="entry name" value="PG-PI_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033917">
        <property type="entry name" value="ML_PG-PI_TP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042275214" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="9">
        <location>
            <begin position="34"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3213968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="156" mass="16903" checksum="C43FD244AC6FB78E" modified="2024-05-29" version="1">MRFFLLPLFSVVLSTPISQWPLIPFGSSSVVQPIISCGVDTDVFIPKKILVSPDPPVRGQSITLTIEGTLSEDVVDGAYADIKVKLGLIKLLETKVDLCSEIKNVDLTCPLKEGELTIVKQVDIPNEVPPGVYKVHVAATNADELSIACFDITIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWU3</accession>
    <name>A0AAD5TWU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vesicle transport v-SNARE N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007678</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000767">
        <property type="protein sequence ID" value="KAJ3212696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWU3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vesicle transport v-SNARE N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3212696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="184" mass="21229" checksum="5DF218C63781EC9D" modified="2024-05-29" version="1">MLDPTNSSEVFENYQQEYKTLTTDIQEKINSQLQNVSNEQKKLLINQITRELEEADEIVGQMEVELMSLPQVTRNRLTAKVKQFKDEVKNYKKELNKQSNLARSGLERDSLLGGGNSEIESRQMDQRSRLISGTERLQDEGHGISTLEELNRQREQMLRTRDTISTADAWIGKSQGVLKAMNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWW7</accession>
    <name>A0AAD5TWW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000776">
        <property type="protein sequence ID" value="KAJ3212494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWW7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042124828" evidence="2">
        <location>
            <begin position="19"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3212494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="216" mass="23438" checksum="C06AF320574E1A7B" modified="2024-05-29" version="1" fragment="single">MKFSTVFTIAAFSTAVIAVPAKDDPANPSDPRGISGPNQHGHSCHWYEHHNLQAPASCNPSQEDTKYDIENPQPCEEELKTYAKPKAEKAETYGKSKPEDEKYSKAKPEAEKAETYGKSKPEEEEKYSKAKPEAEYNAKPTSTPCLQPTSTALPENYEKPTKAYETATPKAAEEKQYKATAPEATTYAAAAGKADYSASNLESSSSKMAASLFAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX99</accession>
    <name>A0AAD5TX99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002984</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002022">
        <property type="protein sequence ID" value="KAJ3199855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX99"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="78" mass="9203" checksum="4F7DFBD5B50D8754" modified="2024-05-29" version="1" fragment="single">YKIMIFDQQTLSTVSVVKTITRNTNKLVQNPENIEEILPKYSEKQILNEKDLPTTHTDKIEKTKKRFNIPIDFAQRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXB9</accession>
    <name>A0AAD5TXB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_007101</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000661">
        <property type="protein sequence ID" value="KAJ3213971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXB9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="1"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="111"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3213971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="454" mass="52329" checksum="B1C397F9CB76EF71" modified="2024-05-29" version="1">MCFSCGYKSTYRLETYDNISLSLEFRMTTKIENVLTNYILPENLVDCYTCQKCSLTETLNFYNKILEKKDSFLNELRLHKKKIYNNIPLQTEANISTTAFIASTTVNSSISNSENTVEKRGSSSLQNKKKKKKNNKKKVKKNNLDGIFNAEDNTNQKSPNPTPQEFDDLIRENLFQLIKCQREVEQIKEALLHAPETDLPKGIKLQKVITPLAKKQCVFANQPKILVLHMQRSIFQPNGYVRKNNTRVEFEEFLDLKKFSTCLKDENFGNSKEDGVRFFGKGGNLWKGGDDFSLKRNDIVKSGKNFECSKVNAIKNKSVDEIREDENTLVDISFTNGSIATVETADCEKNKPPLNNKVGKRTVDTENVTLNFEDDFKENKYLYRLQSVVIHYGGHDSGHFVTYRRCSQKKNKEDKTGGVDPWFRISDESVLPCNFEEVKDIGSQFVYMLFYEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXK6</accession>
    <name>A0AAD5TXK6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007102</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000662">
        <property type="protein sequence ID" value="KAJ3213945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXK6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF7">
        <property type="entry name" value="OBG-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="281"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00068719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3213945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="376" mass="42312" checksum="4AC73ABF147DFF07" modified="2024-05-29" version="1" fragment="single">GLVGLPNVGKSSLFNLLTEQSAAAENYPFCTIEPNESRCAVPDARYDYLCSLWKPPSCYPAYLQITDIAGLIKGASEGAGLGNAFLSHIQAVDGMFHIVRIFENSDVIHVDDEIDPIRDIKTINDELCKKDITFVENAMRNEEKAVKAGAGKYKLSPVFKETFAKMMEMLEQNIPIRNGEWTTEQVHIINEKTRLITTEPMIYLLNMTQADYIRKKNKWLGKIAAYVKENGGGSIIPFSVEFEQNLWNLREDPKKQEEWLKEVGATSALPKIVTQGYNVLNLIYYFTAGEKEVRCWTIPNGALAPQAAGVIHSDFERGFIKAEVAAYDDFKQYSEGEKSMAKVKAAGKYRQEGKTYVVKDGDIIYFQFNVTAPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXT0</accession>
    <name>A0AAD5TXT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Folylpolyglutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FOL3</name>
        <name evidence="10" type="ORF">HK099_008600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000963">
        <property type="protein sequence ID" value="KAJ3209031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXT0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF0">
        <property type="entry name" value="DIHYDROFOLATE SYNTHETASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="129"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="178"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="555"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="713"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="560"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="715"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="758"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3209031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1206" mass="137983" checksum="0AF41926BF440411" modified="2024-05-29" version="1">MNINETFTLEQFLSTPQSNFFQEDNNCTQFQNYPNLISPSFTKQLPIKLNQFFFSQNSIPSMNSPSQIKTENSFDLLFQNAISIFQTQTTLKQTTLTSLPEITVPSTPPINEKSKKTTPTKNIDYPVSLKCCICSYTFKRKHDLKRHHRTKHLNIKPHQCKYCKKGFGRRDALERHTNVPPPFGWKNKMATSPLPTNDGNTTNTSPCKHTSPGSKIPVPIKVNTPLKETTLPSSPPKNLSTSPIKSNNQFNQSHTSPKKKKKQQTQKFTEEIIDDFKTYSKSHHQDTEVVEKEERILQPQTPQKILKTLSRVEEFETIIDKKNKDLSLKLPNKNFLNLLQENITSSANTPNRGLALEAKRVTNFLNNNDSDKIENIEKSSSKDVDKFFELKATANTPVRKLAMESKIVTNYLKNEIVKNENLDKLINKDIDNIEDIIDLNSTDLNFGDSSEEMDELEPSMEVGFFKCDIESINREVSESFLNDEKIEDIFSEQFENIADEKPMIVDELCHEESSVKEDDIIDIEKNETPKSKNSKVLNSPLGQEIIESIAETVDQDIESESNSADESCSDFNSPSEQRRLRMSNSILTKKEDLVIKNEQILFISENEILKSNLGMDNGFNKEDPALKLKLETKNTFEKEILDEINYVIENNSYFEEVEEASKYDISLLSESDAIPKKNWDPEVDEDLPPVDDSEKNFEQLLTDDDISYAKKEIGENTTSYPLDSSSESAKDINNSDIKESIDISTKNEPIQQKKSELSDDESLSIESDEENIDDLNEKNIESFKALLEFIEIGKKYQRSRINKEKIPITDYEEHLKFIAKETEAITMEMNKCLAMQNQISIQEKEFENSKNIIIKRNEELKKLELVNENIKKLNIQHEYKMRHSKTTNSIFSLALKTIIVSSCLMLANDATNVFTNPLCCVFTSISFDHEALLGNTLKDIAIVKSGIIKPNSKVFSTANQDPEVLKVLKSACEVSKSDIKFSSNDLKFFNLNSNEILTKFKENSEFKIQFYLLGEIQLENLSLSLTVLETLNLCQEDEIIEGLKNLKNWKGRIEKFIYRNKSTDKDIAFILDGCHNPASAICLSNFVNGLRKADNKKILWVFSLTKGKDAEQILTKLLSESKEDEIFFCGFSQPQEMPWIDCVPPKDLLNLAESKFKKNLRSFNYGNSVLEALKFIDAKDDIADFNVIFCGSLYFISDFHRQFLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYW2</accession>
    <name>A0AAD5TYW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006456</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000558">
        <property type="protein sequence ID" value="KAJ3215233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYW2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF7">
        <property type="entry name" value="FUNGAL TRANSCRIPTIONAL REGULATORY PROTEIN, N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="290"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="385"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="337"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="395"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="409"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="460"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="482" mass="54058" checksum="F86D8DDE33DD5610" modified="2024-05-29" version="1">MSFTTDTELHHEGNLTIKNNSSNTDAINLSNENYISISINEKPPAKRTQVRNACTNCQKACKKCDEVRPCWRCKKYDLQDSCSDSIRKERQKGMKRGPYKKKNSEVVAVKRKVINDEEDNSVKSEEHNGAKIVKKRKAYKKKQKTVASPETVTSDSIKVEQQPVENENQLLILSELCSAVLSTNEDQTVNETSLIKEEENLENVAVKKEESQYFLPTPPRELSLNKQNDATKIVEFNAHPEFYSNFSINVDEVDSFRYNETVLNKATKNCLEEQDVVTCFGDAALDIPPPHRPPIVPRPKNTLLSPTPAPTPPVRKVSINFSPPPSPTYTSSNFSSEQLKANSITQADTPISPTHSITARGPSPNNNISQLNYNFLATDQRYFNSSSASVNRPTSPIPGLPKRMPSPQPYLSSRSTSPQPYVSNRSTSPQPNFSNRMNSSQDLNSMQRSYSSRYGEKSKGSISSKRSLNIINTNPHLHLKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ40</accession>
    <name>A0AAD5TZ40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Far11/STRP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000422">
        <property type="protein sequence ID" value="KAJ3217550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ40"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040185">
        <property type="entry name" value="Far11/STRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021819">
        <property type="entry name" value="Far11/STRP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239:SF4">
        <property type="entry name" value="AT25231P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13239">
        <property type="entry name" value="PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11882">
        <property type="entry name" value="DUF3402"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Far11/STRP C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="180" mass="21674" checksum="D1C5CCF4F9975947" modified="2024-05-29" version="1">MKVISMIYSKLKPALWEDYLSGDSDVDIEEAQAQEQNIRNLIDFYHERVYKNIYQKVEEHSTISDIEKLKLEKEIKEKEVLNQLDENFKENYKEWLNLEVFGILGETRETLFTLTRRFSREMLKEKIERERDYVKENGNSIIFGRKNEFFGSNIIEEDYDEKDKDTGNFGWNDLVEDLMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZE2</accession>
    <name>A0AAD5TZE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000382">
        <property type="protein sequence ID" value="KAJ3218392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZE2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF18">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="57"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="519" mass="61033" checksum="A3D7C10D0EFDCC99" modified="2024-05-29" version="1">MPNYLYNPYTDTFTDSSEIDYIEGQRSKIEEVYIPDFLMPKLNKKLFEEKYKILGLRKQKNNSEKGEDYELFTIKRKYDEKLYKCKAIKESEIKSIYEDPLTAMKVPMEIFVLNSLKDEKDLSVIKYVEYFYKKEKNFFGEVNETEGSFYIISEYLDQNWISLNKYIGESGLKEKEAKLIFRQIYSTVEELERRGYFHNDLSTKNILINMKTKKIKLINFGNAVFQTYIPDNNRRDSKATKSNIGSTDSLLPIEQNNSFNLNTTHNFRSNLSLNATPKFGSPQTENTTNIEKADFSELSSFFNGQTPESSRALGSTVTFQAATEKNNNYFTYNKLSEQRNSFSFFQEPQEVFSLGKLLEDLILGNKFRLVFETSEQDLNEKETKLKKYLIKKKKRSTKILKQNILQMLDPNIDTRIQFKSLHNLKFCCESFKSKDIKLAKVKNIFQMQFQRLRSYPSVSSLPSVSIESNYQDFAIEDYSSFVSITSTNATNKDIFYRFCRNCIYYFSYFSCKTHHDFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZL6</accession>
    <name>A0AAD5TZL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000243</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001046">
        <property type="protein sequence ID" value="KAJ3207586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZL6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.450.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047002">
        <property type="entry name" value="Tcp10_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026581">
        <property type="entry name" value="TCP10L/CENPJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10331:SF6">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10331">
        <property type="entry name" value="T COMPLEX PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="49"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="501"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3207586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="883" mass="103936" checksum="04B68BA4602BCD99" modified="2024-05-29" version="1" fragment="single">MLTHETKINKAKFSLFGNNNYHENTPLPRKTLSFEELMEEKLLLYNNPTKNQLSNNYQSPFSNNNSQTSNLTEVEPYSNTSFSEETSNTNYNYHLENEFKEHFNKEEHETESSLGSKEKDDENFPFRSDICKIKNESSRLYYDLNENNYQNTTSLEKVLVPNYDDCGYTVDNETNVSVDYAEDQNLHHLEYIEKLKFEQEQKWIESNKLELSALLEFERMEKLIKALEDEELHINNHSCESVEINESIDELSSRAYFSDDHNIKDSKIVKTTTEKGVDSLQYSNKYLEDSINFSEISDIASEYKYDLEDDHNDTLGHTDTNDFKENQTTPNKLTTDYIENNFFTNSEFPKENIVSHEQEELGLEDNEADKSITPRQSKLVQKIFKNKNTFNNETPIKSPIPNNTAKLKKDEDFENDFKNEIISLKKLLYEKDKHILELEKKNSNEKVLEKRKLIKEKEDFEKFRHDEIEKIENFREVELKKIKNAKIILEKQKKANLILPTKKENLTIQSLKEELSSQEKKFKLKESKYLLELDRTKKNLENTKNLIQELKEESKVLESSRLNLIEENRILIFKLRNFEVENKNLKLLQEKNQSIASFKGEDGLSDSSSDLFASDNECQDERLHEEIDIKARNKNHSKEFQDEQHNNNISNDNNFNKIANQHNENQIQLQNKWNNNFKYSNATFDHEQISTYMEKPNVPNLYQCKVNQIENDESCLNDLPSCKRRYSKNVIENFQRSKQILDELAAKIGLPENYLKEKHYSDGKLERTYFNGVSLSWYKNGTTKESRPNGFSCIRFLNGDYKTEELDGSSKYFFAKSKTLQITFVNGTKIFQFFNGQIEKMFKDGKLEIIFPDLTFKTVLPNNSYKIVYPDGTIEKSKNFLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZX0</accession>
    <name>A0AAD5TZX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000744">
        <property type="protein sequence ID" value="KAJ3213109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZX0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="129" mass="15120" checksum="0314CBCCD7D9598D" modified="2024-05-29" version="1">MSGKDLIYRLYLTLNILISKINHVKKKTIFGKELEQKIFKNIGQESTSERQIDEEKCKYLTSATKTSNNLNFNIQNLLLGKFNFFNYGLNDNETCSRSVFSLFKTNSNFNEEVEFLLEFEESYVYLPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U031</accession>
    <name>A0AAD5U031_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase DED1</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-dependent RNA helicase ded1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">DDX3X</name>
        <name evidence="16" type="ORF">HK099_004616</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000330">
        <property type="protein sequence ID" value="KAJ3219721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U031"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000397">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="213"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="409"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="88"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="575"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="10">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3219721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="657" mass="73002" checksum="4F8AEBA48B513AE3" modified="2024-05-29" version="1">MVCKQSEKLANVSLSGEKRERQQYVPPHARNRSGDSRAFDNRSSDGEQVRSNYHSRGYNSGNSFNNGNSYNNRGNFYGGGNRGGFDRSSGGGYNRGNDSFQKKDNWGGSRYNSNGGGNYNRQDSRFEKDPNDPFFDRDDVKPRDTRLEDKLFGSQHNTGINFANYDDIPVDVSGNDIPEGIESFQASDMDELLKDTVTKAGYHNPTPVQKHSVSIVCAGRDLMACAQTGSGKTAAFLLPILSQNFKDGPPPPSQDYGYRRKVEPNALVLAPTRELAIQIFEEARKFSYRSWVRPCVCYGGQPIGDQMRDLDRGCGLLVATPGRLVDLIDRGKISLGRIGYLVLDEADRMLDMGFEPQIRRIVEQENMPYERQTLMFSATFPRNIQMLARDFLQDYIFLAVGRVGSTSENITQRIEYVEDEDKRSVLLDILHNDLDAAEANGTNNLTLVFTETKRAADMLCEFLLDNKFYATSIHGDRSQRERENALASFRSGRTPIMVATAVAARGLDIPNVTHVVNFDLPSDIDDYVHRIGRTGRAGNTGKATAFFNLGHDKNILKELTELLREANQEIPTWIAQKTREADRENQQRSFNKKAARGRGGGGARFGASDYRNETRSNTGGGGGGGGYNSGGYYNGGGYGGYNNNAGNNNSSFDDHWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0U2</accession>
    <name>A0AAD5U0U2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Dynein intermediate chain 2, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DNAI2</name>
        <name evidence="13" type="ORF">HK099_006799</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000609">
        <property type="protein sequence ID" value="KAJ3214578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0U2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000584">
        <property type="entry name" value="Dynein intermediate chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF7">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="505"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3214578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="575" mass="65687" checksum="DE8B164987D8413F" modified="2024-05-29" version="1">MEIVYVYQKKRKEFGKQTLFSDKLAELTNEILPDPSLAKNFIERVECNVETQSLPDKSEHEVNTESFTFINRGILHLQGGWPKDVDPSDVEHTIRYRKKIEKDEEYIRSVKGMGDIMEHCIKQNNAIDIYEEYFIDETDTLVTEEPIAKSLNVYKDPNPVKRCASYVSWYPEDGTKIAVAYSVLQFQKMPQNMCLDSYIWDVENPNMPDLTLTPTSPLVCLKYNPKDPHILVGGCYNGLVSYWDTRKGSYPVDSSAIEKSHRDPVYNVQWVQSKSGAEFFSVSTDGQALWWDIRKLSEPTENLWLDPEKNGRIVGGTVLDFETTMPTKFMVGSETGSVFMCNKKAKNPSEKITHIYPGHHGPVYALQRNPFFLKNFLTVGDWTAKIWAEDVKSSIMSTKYSNSYLTDGCWSPTRPSVFYTGKMDGTLDAWDFIFKQNEPTLTIQVCLVCNSPIHCVKVQEHGKLLAATARDGSTTILEVSDLLSKIQPNEKIIFSQMLEREAKREKTLESSAREKRIKAAQKRPNSGSLKPVGTDLNELIKASEEDFYKCIEEDQWEREKMLEKEAKLNAALNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U172</accession>
    <name>A0AAD5U172_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000551">
        <property type="protein sequence ID" value="KAJ3215331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U172"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd13437">
        <property type="entry name" value="SPFH_alloslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="2">
        <location>
            <begin position="76"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="319" mass="35770" checksum="CBB0FA831186D1E4" modified="2024-05-29" version="1">MQPTLPQPTNTIGPFPCTSLINASPQAITPMSTQRLFFHEIPVAKSEDYLYEGCLTFWGKFFGMIGATPCGWCFPNPYKIINQGEVGLITKFGKYYKSVDPGLYEINIFTELVLKVNIKLQVDQIYQQTITTKDNVSCQIDSVLYWHIVDPFTARFLVENVRVAMIERTQTTLRTIFGTKTLQECIEHRESIAVEISELIDKPAAGWGVKLESILIKDLQFSKDLQENLSAAAKAKRIGESKVIAAKAEVESAKLMREAADILNHPAAMQIRYLETLTGMAKSSDSKVIFMPASESEFQKKAKNDLSEVVSNPFLNEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1F1</accession>
    <name>A0AAD5U1F1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA polymerase</fullName>
            <ecNumber evidence="7">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">POL3_2</name>
        <name evidence="9" type="ORF">HK099_003896</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000262">
        <property type="protein sequence ID" value="KAJ3220937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1F1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="8">
        <location>
            <begin position="370"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3220937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="750" mass="84514" checksum="F75CB5DF95FFE5CE" modified="2024-05-29" version="1">MIKLLDQGWIPIWTGYIKIANRHELDHDDSRSNLIYVRLAKDSMRIWSDIMVEYQIPESYGILVKNTAINPSSNVDILPSINSDIGRTRVAAVLGIAPFCIPGLGVSRPLSLPSVIKIIGLDIEQSTYYRRGAFPLPHDPLISIAIATWDGRFYCGYIPGKHDEDICAPSNNYKIIKFGNSTELADWAIMWIVKEMPDFVAIHNGFKYDISRLGVHCSSSFSKYFIELNLGKVDKGYDLIIPGITVIDTYWFLSKLHNTDYQTFALDALASSIGESGKLQHPTMQINVTDHNIDMTKMIQYNIHDAYLHIQVALKTRCLTEICTMCAVFKAPICDITRFISGTVVCSMASSYALSKSLVIDWSEDDLFNVRFRGGFVMTPITGLHKNVIVLDFASMYPSIIIGANISPETVHVVTDENVRLKIIRDYQLIRPQTEGDIALGWNSEFIFIRSSDVVFCIDRSEESISAQVMKELVSRRKSLPDKNSAEGWTLKIGANSIYGVYGASTSGLSSRLSAISVTGIGRYLIGKVMELATILKFEVLYGDTDSVFIKVGLGCKSNSDDLMDMYHQWASQTPFFTVRLEFDKSYSDIILIKPKIYFGREYGKDHSKPMMKGMASKRRDRPDISRTILKNVCNIICDNNIEIATRKISQLLYDTYKNVNRGLIKYDLCMKEMKREGIIIYSYRSVSGQHITLDKSKYDGGIPEPIDTIWLMNSIKSSISNVLSVCGIPTFDRLIDKIENLADDIEDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1L2</accession>
    <name>A0AAD5U1L2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000508">
        <property type="protein sequence ID" value="KAJ3215950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1L2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="3">
        <location>
            <begin position="157"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="2">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="336" mass="38680" checksum="60067EF92C422FC5" modified="2024-05-29" version="1">MNNYVTAEEKVNQDNKKYMFLKEYKVINEAEIFDDLLEIRVSEKNYFNDMTLALDITPDQVLESKWQFIITDPGAKALDLTGLTKSYISKFIDEYIKNEFEASANGVGLLPKAEFNSQTRKFKPFYYCILKSLTLDMKLPNSISDVLLMIDFSLRDFEKFDPQTYKLKMTEFKTLKEMSNGCGISLVENRYGMVELRNYSHIEHFKDMITNLNGYFNFEEFKSVFLGDVEFTASDLIVNFINNSPGVSNKNFIWFKKFVSELSSKTAIDLYFEITGLKTFAKHVIIKINITAKSDLLPVSHTCFNILDIPNYDTETIALKKFNCWVANFGGGNGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1U4</accession>
    <name>A0AAD5U1U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">LicD/FKTN/FKRP nucleotidyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000360">
        <property type="protein sequence ID" value="KAJ3218893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1U4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009100">
        <property type="term" value="P:glycoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009644">
        <property type="entry name" value="FKTN/MNN4/W02B3.4-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007074">
        <property type="entry name" value="LicD/FKTN/FKRP_NTP_transf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407">
        <property type="entry name" value="FUKUTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15407:SF28">
        <property type="entry name" value="RIBITOL-5-PHOSPHATE TRANSFERASE FKTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04991">
        <property type="entry name" value="LicD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="LicD/FKTN/FKRP nucleotidyltransferase" evidence="6">
        <location>
            <begin position="148"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3218893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="316" mass="37731" checksum="E2027BA06B478E7A" modified="2024-05-29" version="1">MKFKEIKFHHVFKAANFYFVVVIFVITLVFYSHFIPQQQNLNPTITVIEYQWLPKILQDTKNSLVKAEQKIQNFNTGKLLNVSLTALIPQTHDFKNDSTFVKVPDNKYFYEANWDNHLDARWGLKNLTHEKIKISLTETIKAFSKFSNKQGLRFWICHGTLLSWYWNKKIFPWDFDIDIQISWEDLNLISKHNQTFLEDRFFIDVNPWSKFRYHQQHNVIDARIIDKTTGCYIDITVIAKTTLSSGLIHDKSNPPHYYEFEELFPLHETELEGVKVWRPNFAILSLANEYGVTSFEQDYFNKYKFIPEYQEWVYIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1X0</accession>
    <name>A0AAD5U1X0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 6">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PLCD4</name>
        <name evidence="10" type="ORF">HK099_003569</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 6"/>
    <dbReference type="EMBL" id="JADGJW010000234">
        <property type="protein sequence ID" value="KAJ3221368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd15898">
        <property type="entry name" value="EFh_PI-PLC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd08558">
        <property type="entry name" value="PI-PLCc_eukaryota"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037862">
        <property type="entry name" value="PLC-beta_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015359">
        <property type="entry name" value="PLC_EF-hand-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09279">
        <property type="entry name" value="EF-hand_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17787">
        <property type="entry name" value="PH_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="608"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="710"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="PI-PLC Y-box" evidence="9">
        <location>
            <begin position="1611"/>
            <end position="1722"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1722"/>
            <end position="1839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="516"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1867" mass="213815" checksum="C2701B396A8D4985" modified="2024-05-29" version="1">MDSTVFNSLDLKDSESCCIPKEFDLMHYLIKGTKLLKIPNKKSSFFSEKPTERLVKIDELPLQISWQSKKNEFSSVDFNSVREIRRGQNTKAFEYYGKRPELEDRSFSVIYFDGIKYGMLNFIAPTKFDADCWVFGLYRLLNFELQETDISADSFFFNDSKAINSDSLQSFLKNVWNKVDTKNENKLNLVQVVELFKKINITLSVSEIKSAFKNSNLTKNNFIDFYAFERLYKNLRLRRDIAEIFLDLSKTKKSFITYEEFKYFSIEIQKNDWSEEQLQDYYRKYTPADTLQENNELMDIDHFSAFLISANNSIYKKEHLAVFQNMSHPLKCYYINTSHNTFLLGDQLKVESSLEGYIRVLQRGCRCIEVKCWDGPHNQPQVYHTRTFTSKLFLKDVIEVIKKYAFVVSKYPLIISLENHCGIDQQSVIIKLLHDILGSSLLIAPLSSQETKLPSPEALMNKILVLGKELIFKENGAFFSKFESEDDTLTKRPIYNSSMPHQTALNSSSKSILDAVRVSPPASPSQKELTAAKNECNSTDSEKKNLSSSAVEENDKVLLNANLDLRKEEKIEDGEDDSCQHEDVADLKKTDSDSSCGSKINLLQAFINLVIYFKPREFIDFEHSIINFNYNNICFIGEKKSLQLALKQREAYLQHNRRFLTTVYSSPLRVTSKNFDPFPHWKCGVQTIALNHQTFDRGMQLNHALFTLNGRSGYVLKPKYLRSGNCNSFLKTSVSFTIKIISAQQLPKYKGNLSSAVINPFCMLEVVGEDSDCNRFKTKGISSNGLNPIWKESFTFKVKDSSLCFLRFQIFDVDNTNDFIACYCAPLFSLQQGYRHAPLFDWKVESENVKKLIEREVDTICKDLAKLATKEELEQFLLKGQKMSKLSSKVGTKPKEKFVKIELLPLRIVWESKKKHHVDFSSIREIRKGQNTLAFELFGKSQDLDLRSFSIIYFDDIKSGTLNFICPTVADCVKWTAGLEMLLEQHKVLNKPSSPQNFSAVHSSEKISKISPQNSTVSNSSTELFSGNLNNMAKTDAENPVTKAMSPTSNNLLPTVSNLPSFAASFEKEKLYHILDTGIVLLKIPNKPNSKAQERLFKVDCNKLQISWESKKKKKLSFVLFSDVREIRLGQNTKAFEIYGKNPDLEECSFSIIYFNGIKYGTLNFIAPSKRECKFWVAGLHLILAQDSDLISKGNTGWLRKYWNAVDVNNDNVLGLDQVTEVCGNLNIKLSKAEIKSAFKNQRLSKNNLIEFEAFERMYQSLRLRKDIAGLFTSLCNETRSGLTYSEFKNFIINVQKNHWTEEQFKNYYDKYRPQNQVGSGNEESLMDIDHFSAFLISANNSIFKKEHSSIYQDMTQPLSSYFINTSHNTYLLGDQFTGESSVEAYIRALQFGCKCVELDCWDGPNGQPIIFHGRTLTSRIPFKDVVEYGFVVSPYPVILSLEIHCDHSQQEGFNSFIVFLLRNLVMAQIFQDVLGDKLLTHPIKEEETVLPSPLELLNKFIIKAKIVSYGDEIEEDELYPELDTTAPAAKLTKRKSFIGMLSQVALSISPTSSVTNSASYSTLPNMQYLNVNVESSFESSQLSVENLATEEKNINKPLKQPKKSFLSPKLMKLVIYFKTRKFLGFEKCAETFEYSHMCSIGEKNSTLLATKNRTEYKKHNSKFVTRTYPSNLRVNSSNYDPIPHWKSGVQMVSLNFQTFDRSMQLNQALFTQNGRCGYILKGAEKQVKVEGKPALTVSVQIISAQQLPKKKAVEPYVLMEVVCDDIKEIIFKTKAIRGNVSNPIWNEVFRFSVEEPELAFLRFQILGAENLVSNEFIASYTIPILSLEQGYRHAPLFNYFGEFQKFSSLFLKISIDSNLSEDFVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U224</accession>
    <name>A0AAD5U224_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000342">
        <property type="protein sequence ID" value="KAJ3219339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U224"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050152">
        <property type="term" value="F:omega-amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006528">
        <property type="term" value="P:asparagine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088">
        <property type="entry name" value="NITRILASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088:SF30">
        <property type="entry name" value="OMEGA-AMIDASE NIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="203" mass="22808" checksum="2AC42FD0528F4B7E" modified="2024-05-29" version="1" fragment="single">MAKEANVHLIGGSFPEKLNDKFYNTCTIFDNKGLLLGIHRKIHLFDINIKGKQTFKESEILSPGNEVTMVKTKFGPIGIGICYDLRFPELAMIAARKGCIAMIYPGAFNTTTGPLHWELLLRSRAVDNQFYVAACSPARDLSATYHAYGHSIIIDPMGKILSECGENEDIVYGEIDLQFLKDTRESIPVSIQRRFDIYKDVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U225</accession>
    <name>A0AAD5U225_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000224">
        <property type="protein sequence ID" value="KAJ3221535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U225"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025649">
        <property type="entry name" value="DUF4360"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38847:SF1">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE RSUA_RLUA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14273">
        <property type="entry name" value="DUF4360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042008268" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="21954" checksum="4D53FEE924D0E861" modified="2024-05-29" version="1">MKFAVVASLLSALTVAADVPVSGDAPPPGSVTIGKVIYGGSGCPQGTVSQNFNSDNTAFTLLFDSYYASIGQGVPITEARKNCQFNAELKVPQGWQFSLLTIDYRGFLALDSGVTAQQSSNYYFQGSINQARKTSTFTEVNNGDYTIRDTFGLVSTVWSDCNASANLNVNSQVRLSGPSGKNGLITADSTDFKVTHKYGIQWKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U294</accession>
    <name>A0AAD5U294_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_005614</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10 12">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010000446">
        <property type="protein sequence ID" value="KAJ3217058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U294"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.50:FF:000002">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1760:FF:000001">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="entry name" value="Glutathione synthase, substrate-binding domain superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="entry name" value="Glutathione Synthetase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01986">
        <property type="entry name" value="glut_syn_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130:SF0">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 10 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione synthase substrate-binding" evidence="13">
        <location>
            <begin position="205"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="397"/>
            <end position="400"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3217058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="472" mass="53470" checksum="06242AADD137392E" modified="2024-05-29" version="1">MLKQEIYPPTLSILEEKNLITDAVDFALDHGLLIKQKDTGNIIHAPFSLFPSPVSRQAFQNTVDIHTTLNKLFFKLSRDDIFIRKVMKSVIGVDNFMEKLFNIYTTVFDHDTNTQTISLGLNRSDYMLHSSENGLVPLQVEFNTISCGLVTLSSKVTELHQFVHKNDEEILKNLPTCNSIEGVPKGISAAHRLFNSKYLKNEESVVLMVVQPNEWNMFDQRGIEFKLLNKYGIKMMRKSLTEIFNEGKIADGNLVIDNKIISVVYFRAGYCPNDYPTEDEWTARLMMEKSSAVKSPDIAYHLVGLKKFQQILSCPNILKKYLTDPLELEKVRKTFTGLYPLDESEEGLAAYEMALNHPEKYVLKPQREGGGNNFYGNDIPLVLNKLSAAERRCFILMDLITPPTLQNLMVREGKISRQDVQSELGIFGVWLSDGEEVLINEECGHLLRTKKSTSTEGGVSKGISVIDSPYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2L5</accession>
    <name>A0AAD5U2L5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000266">
        <property type="protein sequence ID" value="KAJ3220882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2L5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="58184" checksum="8BB1F679C1746EA3" modified="2024-05-29" version="1">MEENKVFIFYKQGNSEETLYHFDLNNPFFKNLIYVYCWDKANFIYIGNREYMESEKKLIFLLEKDEHCDVVTKPTNENKIHAVNLATAEYEDSDKKIIDSESRYKEEETILTTKYTNYLLSASESILKLKEETGVTLVINKLRCGLLESSTDMGCKIQKRKCVVEETQSDKATCAGCIKKSIECHFTVSQKRGPRKANVADKATSQSQTQPQSQSLRPSQNLQFSNSPEKKNTSFHNNSTPAVPSVNAVTSMPYQLPPNSLLKDEDMLYASYLNGVESTQLTNLKGEQNTNSDVEKTQIQVQPDSTQLQQQSNTQNPHHSTQQLLPSSQQLQSQQHSNHHVSLQQSSTQQQLIKHKPKQQQQLQQNSNQQVQNSHSPLQQNSNVPCLPATPSQIDSSISKAEPEIFSNIDHQRVSFLQYNNLSNTESLPSPSTTLPPFNPVKFKFGSSIKKRKGTDGYSSVNENTYDEITLDLNLRNKIEDNKKRKMEIVLKLMEKGESSEFISDFVKMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Q8</accession>
    <name>A0AAD5U2Q8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative lipoate-protein ligase A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AIM22</name>
        <name evidence="6" type="ORF">HK099_004124</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LplA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000284">
        <property type="protein sequence ID" value="KAJ3220644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Q8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017118">
        <property type="term" value="F:lipoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="LIPOATE-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561:SF3">
        <property type="entry name" value="LIPOYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="5">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="296" mass="33996" checksum="51A26249F46E5E20" modified="2024-05-29" version="1">MNNRRRSGGGTVYHDEGNSNFCVMMPRLEFTRRKNAVMVSNSLNRLGLDTQVNDRHDITLANKKISGSAFKVIKERAYHHGTMLIDSDLKQISGLLTGKDNIIGRGVGSVKSEVTRLSDYSKTITHDLFSKSLMKEFIKTYQREDSKLILDTDNDGEFNLLEFSNSNDIFVKELTMKDFNSSKELNSIYNELSSFDWIIGQTPDFIETSEKFDFYWGQLQFNLVVKEGLIFDFDFKGFEVDPYVQGIEILEICEILKGVRYSTSEVQRKIFDSGLEISQEMKEFVNALANMINFDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2U2</accession>
    <name>A0AAD5U2U2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SPX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000331">
        <property type="protein sequence ID" value="KAJ3219659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2U2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14447">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000720">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="SPX" evidence="7">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="553"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="698"/>
            <end position="704"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="704"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="723"/>
            <end position="727"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="792"/>
            <end position="795"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="847"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3219659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="876" mass="99951" checksum="A71DB1E5FA01B08C" modified="2024-05-29" version="1">MKFGEQLLSSQIPEWRFNYLKYNALKTYLNDIVLEMNELNLNNTSNQISHENLKSFVKFLDLLNKNITLIYEFYSNLKSSITSEIEFFKLKEKNSFFMEKDMNSLQNFILNCFITSIKLKEFVFLNKIGVQKILKKHDKATGGNPNLSTYETNLVTNYLLELTEDDLIEIQSELKELFQKSGGFMDSLQFKTEVRKLPFNIVEKKNFIIDMDGVIYHGSHLLPGVVNFINWLKSTNKNFLFLTNSSDKTQEMLQEKLKNLGIEVSKSHFYTSALSTARFLAKQHNNEKGRCFVIGEVGLKNAISEAGFIIAEEEPVDYVVVGETSSDSTFNFTQISKAINFLNPSQTKVNGNYHDSAELQKNQILNRRSKSRPKFIATNCDVVDRALPSGWSPSCGSFAAPIEAACGLKPYYLGKPNPLMMASATELLGGKREETVIIGDRMDTDIIGGLEAGITTLLVLTGVTTLDDLDKFPYQPDYILGGIDELMQVIFANTQQLGFFSPLNSVQTTPLSVRKIAKKRSMEIDKNLELESKIIKLPSTKVLILGSSDAGKSTLIRGMRIKYVKNFTLEEKEYFKLIIHKNIIDTLKKLIKYYIKNCNLKNNGTDQKVQLQLSTNASVNMEDFYLYLNLFKSHDFKCRLSSEIKNAVQVTWNNEIIKKIFFNKTQCGINIQDTTIYYFNDLQRLLDEQFSPTELDVLYLKNATKTVTETVIHTRTMNIKLFDVGGQKRLRNSWTPFFDDVSMILFVVALSSYNQMMKEDPTVNRLNDSFTLFESLANNKLLRGCKFILLLNKIDLLAEKLKLIPLKTYFNDYEGGADTKLAKNYFRKKFLEKSKGREIKHILFITATELSAMKRITGNLVKVIGNVAMKASPVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2V3</accession>
    <name>A0AAD5U2V3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000164">
        <property type="protein sequence ID" value="KAJ3222675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2V3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="172" mass="19768" checksum="4E91C1F421FC1AB7" modified="2024-05-29" version="1" fragment="single">MLFQQFDTVTIILLSVIALTLIIFSIVLTYYIRRCLIRREKLNQKMEVVEAKDVLFLKPPSLNSLSSSKRTRENRASTWGTSMKNDINGIYLVNLSEEEAKRRELAFSEVGQTSTVVGFHNVDEIDSVGERKNTKNLQRFNSIKTNLVSNLDYYDPTLLGRQLDDELESETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3A2</accession>
    <name>A0AAD5U3A2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DnaJ sub C member 27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DNAJC27</name>
        <name evidence="2" type="ORF">HK099_002090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000167">
        <property type="protein sequence ID" value="KAJ3222620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3A2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002392">
        <property type="entry name" value="DnaJ-like protein subfamily C member 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="177" mass="19570" checksum="5A25C2B143EF097B" modified="2024-05-29" version="1">MSAVNSAKRLKILSLGDSGVGKSCLIKRYCESRFIQDYISTIGIDYGVKSLTLGGVDLKINFWDVSGDPTYLEVRNEFYKDTLGAVLVYDVTSGKSFDALDKWLDELKKLSGNNNVIVVLVANKIDGDPRVISTEEGMGFAEKKGLKYFETSSQTGKGVKEMFENLFEAIILKLNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3H5</accession>
    <name>A0AAD5U3H5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000140">
        <property type="protein sequence ID" value="KAJ3223194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3H5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="80" mass="9396" checksum="5C8EE68A39DA798C" modified="2024-05-29" version="1">MPSINNYLVLDIMSKENNIYKPFWTPDYKTLSKNFMKPLETSQLPLIETQTQFSNFLSLKEVTPSEIITLPTHSNNRKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3R5</accession>
    <name>A0AAD5U3R5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Resolvase/invertase-type recombinase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004016</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000273">
        <property type="protein sequence ID" value="KAJ3220796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3R5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="108" mass="12495" checksum="52A17832B325C27D" modified="2024-05-29" version="1" fragment="single">MNEEEKSKNKSKNKYISIGRAASISGLCQQTLRKLADTNKIANYKTPSGYRRYDVNSIMEMCTAFLFTESDVVRKSSKISRIERTNFIYTRVSSKKQLDDLSRQRTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3V5</accession>
    <name>A0AAD5U3V5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">glutaryl-CoA dehydrogenase (ETF)</fullName>
            <ecNumber evidence="11">1.3.8.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_001291</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13389"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid metabolism; lysine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid metabolism; tryptophan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.6" evidence="11"/>
    <dbReference type="EMBL" id="JADGJW010000135">
        <property type="protein sequence ID" value="KAJ3223317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3V5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004361">
        <property type="term" value="F:glutaryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046949">
        <property type="term" value="P:fatty-acyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01151">
        <property type="entry name" value="GCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000006">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000008">
        <property type="entry name" value="Glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019519">
        <property type="entry name" value="Elp5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052033">
        <property type="entry name" value="Glutaryl-CoA_DH_mitochondrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807:SF1">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10483">
        <property type="entry name" value="Elong_Iki1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="16">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="15">
        <location>
            <begin position="77"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="14">
        <location>
            <begin position="186"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="648"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="687"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="659"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="690"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3223317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="716" mass="80713" checksum="C12458A9012B6617" modified="2024-05-29" version="1">MGSMGLLGSTIDGYGCPGVSSVAYGLIAREVERVDSGYRSAMSVQSSLVMHPIHAYGSEQTKEKYLPSLATGEKVGAFGLTEPNHGSDPGSMETTAKKVGDTYILNGSKTWITNSPIADVFIVWAKTEDNAIKGFVLERGMKGLSTPTINGKFSLRASVTGMIVMDDVEVPAENLLPKVQGLKGPFGCLNNARFGIAWGALGAAEYCVDQAREYTLNRRQFGVPLARFQLIQMKLANAVSEIALGYQACLQVGRLKDEGKIAPEMISIIKRNNCGKSLTIAREMRDMLGGNGISDEYGIIRHVCNLEAVNTYEGTHDIHGLIIGRAITALLCHALKNNFQGVVVFKSMVDETKFEREGPVGENLHCYWLDDETGLICFHSDRIFENGSYLMIIGEVEYSDNYGSFTIKPSKIIDKTKDALFQELVWNLEVVDIHQKIYHVFEKMNFNSVLDSFKTSKVILFLDTVRNPSSEILTTFDLGEFVFIKSSLNFDLKNVANIKNKKIILNLNDLVLTNNTQILVKDLLEYGTHTEKLILIFHKDLLLRKTETDILAENLLKEICNCWLDLDYHFEKTVNYNVNTNTEEEVENEKNTCYFFQKQHNGKIQKHVFEKSFKIIGNKFEFCLLEPKKKLLEEKLIAERKKKEKKKPLPTSSFNLNTSEREKEQKEKAELPYMKIIQESENQILKESFYSDDEDDASSSEEDDDDFDDPDADLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U437</accession>
    <name>A0AAD5U437_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="20">3-oxoacyl-[acyl-carrier-protein] synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">FAS2</name>
        <name evidence="20" type="ORF">HK099_004046</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 4n H(+) = a long-chain-acyl-CoA + n CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.86"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">[Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000277">
        <property type="protein sequence ID" value="KAJ3220740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005835">
        <property type="term" value="C:fatty acid synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004321">
        <property type="term" value="F:fatty-acyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00828">
        <property type="entry name" value="elong_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03447">
        <property type="entry name" value="FAS_MaoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08950">
        <property type="entry name" value="KR_fFAS_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.20:FF:000005">
        <property type="entry name" value="Fatty acid synthase alpha subunit FasA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.930.70:FF:000001">
        <property type="entry name" value="Fatty acid synthase beta subunit dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000078">
        <property type="entry name" value="Fatty acid synthase beta subunit dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.366.10:FF:000006">
        <property type="entry name" value="Fatty acid synthase beta subunit dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000168">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.25.70:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3330:FF:000001">
        <property type="entry name" value="Fatty acid synthase subunit beta dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039569">
        <property type="entry name" value="FAS1-like_DH_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013565">
        <property type="entry name" value="Fas1/AflB-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041099">
        <property type="entry name" value="FAS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040899">
        <property type="entry name" value="Fas_alpha_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047224">
        <property type="entry name" value="FAS_alpha_su_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040883">
        <property type="entry name" value="FAS_meander"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041550">
        <property type="entry name" value="FASI_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003965">
        <property type="entry name" value="Fatty_acid_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050830">
        <property type="entry name" value="Fungal_FAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032088">
        <property type="entry name" value="SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982:SF21">
        <property type="entry name" value="FATTY ACID SYNTHASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10982">
        <property type="entry name" value="MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08354">
        <property type="entry name" value="Fas1-AflB-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13452">
        <property type="entry name" value="FAS1_DH_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22235">
        <property type="entry name" value="FAS1_thioest_ins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18325">
        <property type="entry name" value="Fas_alpha_ACP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18314">
        <property type="entry name" value="FAS_I_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17951">
        <property type="entry name" value="FAS_meander"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17828">
        <property type="entry name" value="FAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16073">
        <property type="entry name" value="SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01483">
        <property type="entry name" value="FASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="18">
        <location>
            <begin position="2205"/>
            <end position="2284"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="19">
        <location>
            <begin position="3127"/>
            <end position="3667"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="3467"/>
            <end position="3494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3220740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="3901" mass="433185" checksum="922B69825F9AACFE" modified="2024-05-29" version="1">MSKESSLRPLVLKHDLIQISIPIPLQEWPIAERIKDQFLLEPSIDDVTPITLIISLIHFTRVFAQSNSNGNGQSNSELDFYPFLTVLFRFFQENFCKNNIHISIKSLNKEQKLFVLKNYYGLLVTLKKNGFITKKEHSLEKIPTLLSAISAERASALVIFGGQGNVDDYFQELVQVYETYYSITRSFIHAVATTLSALSKSEKAKSLNANPIDLLQWLENPSSRPNTTSLLDTDISLPLIAVTQLLNYNITCKALDFTPKEFRSYFAGTTGHSQGIVSSAVIAASSTEQDFLNNAIKAITLLFWLGLRAKSAFPLTTLGPNILQDSLANNEGVPTPMLTVTGLPLKDVKKHVDASNAHLQESSRISISLINGPRAIICAGPPQSLYGLNVALRKFKANPNEDQSRVPYTQRKLRFNSRFLPVSVPFHGFYLEKVPSQMEKDVIESECSLNDFELAIPVYNTNTGEDLRSCKNLTASLIEQIAVLPVNWELATAHKTTHVFDYGPGGASGVGGLTHRNKEGSGVQVILAASLEGTTELLDKSSLFDTISPVPYSQNWVEEFRPKLVRIAGTDTIHLDTQFSRLLGKPPLMVAGMTPCTVDERFVSAVINAGYHVELAGGGQHTEAYLRDRVKKIMERVAPGEGITLNILYLNPRLWGIQYPATMAMRKEGIPMEGITIAAGVPSADVANEILKNLMESGIKHVSFKPGGVDTIKRVIQIAKNNPDMPVILQWTGGRGGGHHSFEDFHQPMLETYASIRKVKNISLVVGSGFGNGEDTIPYMTGQWSVKFDYSPMPFDGVLLGSRVMVAKEALTSPAVKDLIVATPGIADETQWEKTYKGEIGGIITVNSELGEPIHKIANRGMMLWREIDDTILSLPKDKRLPALLAKKDYFIEKLNADFQKVWFGKKTGGKTCDLIDMTYLEVINRLFETLYISHQKRWLDFTLRDTFGDFLKRVEERFTNKSNTLSLLQDYEILNQEPAAFISKFADSFPEASEQTLTQEDVFHFLTICSYPWRKPVPFIPVFDERFEFWFKKDSLWQADDLEAVPDQDAQRVAILQGPVAVRFSDKANVPVKEILGDIYQENIKAVKSLYYENKVENIPVVEYLGVLPAEKLKSKLNGITLTPLKDGNETSIMFEVSRKASEIPSLSEYLSYIAGPKPSWLRALLCSDAIVQGKLLIPNPIKNVLKPRPNQTVFVKLNKNNDPQVLTVYDQSTEGQIPSRNPALILSVGSENVISLNIFEKRADDFISLEFLFKYERFQGYNPIHEIMEGRNQRIKDFYSKLWYVDKSKSNLTPYDTFTSTFKITSSQVSEFVNVVGNQAHAYLIGQEGKTETPMDFSIVSGWKSLVTAILPKEIDGDLLRLVHLSNEFRTLNNEVFYPGDVVKAEAIVNSITITDSGKIIEVKETLYKESIAISQVISRFLYRGTFTDYETAFTKKSEKPMQVILKSQKDISVLKSKSWIKWKEAAPELLPSSKLVFRLTTLSKFKAANTYSMIQTEGSVFLTTSKETIEVGVVNHCDENAHGNIILEYLKRNGKPIEQEVYFKNGGYSVLPVQTLFPASVTSPPSNKKYSLASGDLNPIHTNPYFADLAGLPGTITHGMWTSASTRKFVEIFAANNEPQRVKSYSVTFVDMVLPNDVLSTKLFHVGMANGRKLIKVETFNQRGSKVLEGTAEVEQQPTSYVFTGQGSQEVGMGMDLYKTSTISKEIWDRADSHMLNEYGVSLLEIVNLNPKTKTVYFGGKRGAAIRKNYMSMVYDIMSDGVLKSMPLFPTITEDSPSYTFSHPTGLLSATQFTQPALTLTEIASFQDMKANGLVQQNCPFAGHSLGEYAALASVGEVLPVESLVDVVFYRGMTMQVAVPRDSEGRSNYGMCAVNPLRVGSTLGEIGLKFIVNSIAKLSNGLLEIVNFNVENFQYVVAGELVNLDTLRIVLNKVKSLNVNLVELSKSKSVAEIEETLDELVTEAIAASKKRLELAGGYLTQERGIATIPLNGIDVPFHSSFLLNGVVPFREILKKKFEARLINVDLLVGNYIPNLTAQPFQLTLNYVKLVFEQTQSKLIKEIIDNWCEEHFLTPSGKQELGYALLIELLAHQFASPVRWIETQDHLFQSFKVERLIEVGPAPILCGMAVRTIKIKYEKKDDAVTQKRVQLCTSKDASEIYYEFEDEKVEEAVPLVQDAAVAAKTPEVAVSAPAKVSAGPIADEPPTAVEVLLALISNKLKKPLSELAPTKTIKDLVNGKSTLQNEILGDLSSEFGNIPVDKAEEIPLAEVAAAIQNNFGGSLGKMSMTLINKLVSGKMPGGFGMGQVKSYLSNAFGLGAKRSDSLLLHGLTMEPAARLSSEVEAKSWLDKVAQDYAVKVGISFAVSTSSAAGTATAAPVMNSEEFNKFKAKIDKLVLSQINEFAKYLNMDLLEGGQTLAAQKVNSNLIQEELDLWVKEHGEIYADGIKPAFNPIKSRVYDSYWNWVRQDALQLYYDLVFGKIPQHLNRDLMNKVTHLTNRSADFESMFQFMEYYLEQWPDKGDEKYERLRSLTKMLTENVKEAIDRDPAYINLMYQPTAPRTTVSDNGSLIYTEVNRKASSMKEYVQELRDGSSLTTLPQSDLAVKFAEIQRLLLKEKLNSKTKTQVSKIISEIQETLPKAAVKMPFISLKSKSASDPLHYEYDEKLTTKYLDILSHIAINGISFKGRKVLVTGAGKGSIGSQIVQMLLSGGAQVLVTTSRFNRDITKSFKELYENSGSKGSRLIVVPFNGSSATDVKNLVQYIYDKDPKSGLNWDLDFIIPFAAFPQEGRELDSVDSKSELAFRLMLTNVFRLMGEVKLAKQKNGFDTRPAAVLLPLSPNHGTFGGDGLYSESKIALETLMHRFHSENWGSYLSIIGAVIGWTRGTGLMSANNIVAEGIESLGARTFAQLETAFNIIGLLHPKMVELSQAEPVWADLNGGLQFVKELNKIVYDLRKSLLESAEIKYAVTQEIALDKVVLEGPAKQQPSIVTPRANMKYLFPELKEQRLTHLRGLLDLEKVVVVVGFGEVGPWGSSRTRWEMESTGEFSLEGCIEMAWMMGFIKFHNGPLKKLPAYSGWVDTKTQEPVKDSDVKNLYEAKILAHAGIRLIEPELFNGYDPSKKLFLQEVIVVDDMPPIEVSKEEAEAFKLQHGDKVVIEQKESQYFVHIKKNAILHVPKALQFDRLVAGQIPTGWDAARYGVPEVMLLDIVKQVDPITLYTLVSTVEALITAGATDPYEFYQYVHVSEVGNTAGGGMGGMRAMQKMFKERLFEKPIQNDILQESFINTMPAWINMLLLSSSGPIKTPVGACATAAESVEIAVDTILSGKAKVVVCGGYDDFQEEGSYEFANMKATSSSAEEFARGREPSEMCRPATDTRAGFMEAHGAGIHILMTADLAIKMGTPIRGIIACTNTATDKNGRSVPAPGQGILTTAKEVKTGLKSPLLDLKYRAKQLARERKSIKVWIAEEYENLKEEVEELKASGEQVSDDYIKERTAFIEKEGTRKEKSALSHWSHDWWKNDPSIAPIRGALSTFGLTVDDIGVASFHGTGTKANDYNESSAVNQQFAHLGRTAGNIVPCIFQKHLTGHPKGAAAAWMLNGVLQSLETSIIPGNKNCDNVEARLEQFKYLLYPSKSIRTNGVKAGILKSFGFGQAGGEILIIHPDYIIAALEENQFKSYLDRRNERQVKSYRYFHETLTGKSPFVKVKNSAPYTDSQQSKVYLNPSIRASYDKKSDSWNFNAGLVDHAKPQVDVTKALVENLVNFNNSTKTEKGVGLDVQLISEVNVENSVFVERNFTKNEINYCLQQPSPNSSFAGRWAAKEAVLKAVSSLVGKPLWTGGAGAPLIDIEIVRKDGEAPVVKFHNDAKKLVKKFGVKNVKITISHSGSYSVAMALAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U452</accession>
    <name>A0AAD5U452_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PHB2</name>
        <name evidence="8" type="ORF">HK099_005162</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000391">
        <property type="protein sequence ID" value="KAJ3218203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U452"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="52"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3218203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="300" mass="33018" checksum="DAF5F93C0DC0154E" modified="2024-05-29" version="1">MNNPQFKNFLQNAIKQAQNSGGGSGSGGVKKMGGLGLLTIGGGALFLGINASLFNVEGGQRAIKFSRFSGVKDDVYVEGTHFFLPWFETPIVYDIRAKPRNVASLTGTKDLQMVNLTVRVLSRPRIDKLSTIYRTLGLDYEERVLPSIINEVAKSVVAQFNISQLITQREKVSFLVREQLVKRANNFNIVLDDVSITHLNFSPEFTSSVEAKQVAQQEAQRATYVVDQAKQEKQSIIVKAEGEATAAQLIGDAIKNKPGFLELRKIETAREIAQVIANSQNKVFVDSSTLLLNVNEAKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U472</accession>
    <name>A0AAD5U472_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000809</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000120">
        <property type="protein sequence ID" value="KAJ3223697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U472"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="91" mass="10638" checksum="5962B6D77BC14959" modified="2024-05-29" version="1">MILSSSFNSIATAKKSLSSHWVKDNTYDDQCCSPEKKVELLEHKKLKEEYKEEVAKESVLMDILRILEKESAKLKSFNERCRLAKKLKENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U495</accession>
    <name>A0AAD5U495_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="3">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">OGG1</name>
        <name evidence="13" type="ORF">HK099_000749</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000119">
        <property type="protein sequence ID" value="KAJ3223729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U495"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1670.10:FF:000005">
        <property type="entry name" value="N-glycosylase/DNA lyase OGG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="12">
        <location>
            <begin position="171"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="446" mass="52069" checksum="858240DDC3C3D91F" modified="2024-05-29" version="1">MEGLNKGFKFLCLSKDLDLERTLFGGQSFRWIKSELQNELIYSSVLKNFEGHFKIYSLVQRDENILFRRELESLTAATQGFTKKENIKLEDGNDFEAIRMEKSINIKEEPNIEGDKDLNFLKSYFQLNVDINELFNVWSNADLNFRMKSQNFKGIRVLDQHPVENTFSFICSSNNNISRITLMISKMAKKYGKFIGKFNDVEFFSFPEIQDLAKDVVEDELRELGFGYRAKYIFKSAKFLMNNGGEDFLYNIKKLPYFEAKVELLKLTGVGPKVADCILLMSLGKTEAIPIDCHVWQIVTRDYNFKSKSKSLSSATYLEIFEMFYKIFGVYAGWAQNILFCADLRQFKEKKSKRTLSELELDEIETKKNIDDKVPLENSIIKNEEIEDLENIKMEDAKKENDIISYSVKLEKTIDLANENGEVFDLFSKQREYANKFLESRARYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4L3</accession>
    <name>A0AAD5U4L3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED31</name>
        <name evidence="9" type="ORF">HK099_008574</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000096">
        <property type="protein sequence ID" value="KAJ3224330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4L3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1340">
        <property type="entry name" value="Mediator of RNA polymerase II, submodule Med31 (Soh1)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038089">
        <property type="entry name" value="Med31_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008831">
        <property type="entry name" value="Mediator_Med31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13186">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05669">
        <property type="entry name" value="Med31"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0010">Activator</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="144" mass="16550" checksum="36898B9B679B7F2D" modified="2024-05-29" version="1">MDSKVVDGALNASLSESEERSRLRFQLELEFVQCLANPLYLQCVYPICLEILDLLQNPSFREATASSEIATFIHHKEFFHWQHRRVFTGVKDNNDLKIKKEVENFDIGNSTKSENSGESVKVEDAEQIDELNMGDLVFKILNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5B4</accession>
    <name>A0AAD5U5B4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007733</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5B4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF80">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="4">
        <location>
            <begin position="37"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="22459" checksum="00B5199F5D1B1A9A" modified="2024-05-29" version="1">MNDASSGIRSSELYDWFKDFSHFEEFVSANLKKSDKILMLGCGNSKLSEDMCLKGYKNITNVDYAENVINFMKERNLDKPEMKWITMNIKDMSDFSNGEFDAGDVWDPPEELKVEVGKYLKEVSRVLKANSGKFLYITFGQAVSLKFSLQLTEVQHFRKIFLDKSEYNWKIETNTFGDAFHYFVYLMLKNCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5L8</accession>
    <name>A0AAD5U5L8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007084</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000066">
        <property type="protein sequence ID" value="KAJ3225258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5L8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="277"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="437"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="489"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3225258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="911" mass="103886" checksum="FA506930B9E0077C" modified="2024-05-29" version="1">MAKKRKLVKPTLKSLKILFYFCFSFTYIYLLRFRSISKGSSSSSISNSKASLEQKNPDPCKHIHPLVKLQNLKKLFSISKPLKECQLNNCKNLNSPNVDYNTWICLCCAETYCCSKALVKGETGNNAESGGNSPQLIRKSQRLLAKKSASEIYIDANPVDNLLNEDLLNKKLEELNSSDDYYVLEPNSHAIQHFNDSKHSIIFCNDTAHFYCFLCQKSMIYNSKQNATLLEAKAEILKWFDKPKYKSSTDHDNQNTNTFGAKARRKSNKRSEKVLYPGLTNLGNTCFFNSVTQCLVYSDPVKREVQKLREEEMGLVILSFKNFLADMESSTKTVNPKDLFAKISLKFKIYKGFQQQDSHELLRRFLDELSEEHQTLIPKKTPTFIDKVFRGKLVSVIVCLECGFISPSFEDFLDLSLPLNPVKSKLFSKDIFKRKKPTTLNNDGEGTGISGTQLNRSDSKSDSSVEASNYDTSNGVRSSSPFSHDSNASSPAHSPSRFSSPSPSQIIDNVNIHLPINENQTFWIQSLLKKLQKNTSDVNCVDYCLNNFFAKENLSGENSWSCEMCTKRKFEEEMNNKKDGIVEFQKHQEGTITVENASKNVIIEKLNLLSITDSSIPKHNIISPIPISPTSGIPNFLRNEIGLTNSADEFGNIVKDSTPFSNQHICDQGEFEKNANSSAQHHETFHNSQNCKSSELKLIESPNSLGSKNCSPNNTSHTFKSISSPKPAFFKSQKRYLIHKSPEILVLNLKRFQQMNGIFSLRGTKKIEDLIMFEEYLDLGDYMADFQVLQDLISFNDKLDPKNKDLEVKHDSTKLAELDLSRKNHIYRLYGVVVHSAFSFFNMKGSLFGGHYYSYIRIPRKMDSEEEISSQKEKFEWVYFSDNRVSLSSWEEVKKSQAYMLFYERTDLETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5M1</accession>
    <name>A0AAD5U5M1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4'-phosphopantetheinyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 88 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000266">
        <property type="protein sequence ID" value="KAJ3220884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5M1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052757">
        <property type="term" value="F:chondroitin hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052369">
        <property type="entry name" value="UG_Glycosaminoglycan_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36845:SF1">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G05090)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="4">
        <location>
            <begin position="76"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="611" mass="71674" checksum="63EC10270A8E6ABB" modified="2024-05-29" version="1">MLKELGFKKKKFNEIDIAMQDFCFNDLIIKRNAYGKPILEKVQNLDPEIAEKQIFFNLSHHGDWVISCTGVDIKSLGCDVTQIEVYKNKESLFQFLDCFKDVFTEIEWKYIYQDFLLDHDIAERCKTLYKRFSQFWSLKECFIKAVGEGLSMDLDKIEFEKGKVCSDSFKDIQSDIKVRYLNKELQNWIFEITFLDDLHPVAIGTEYDTLNEKKIFEQAEKVYSNFKFEDPKEFLEEPCFPHYITASKSGFFKKVEFDHRWHLEPKTHWSAPFLVGIYWCIFLVNKNEKILNLAVTAMQSLDFIKDDANIDDIGQVFILGTKNAIQYEFSKPKHDQHVIDNYQKTMLTAAETLCTRFDEKIGCIRSIVNQEDIEFGFSTTIESMMNLELLLYIAQKYPWKKRFYDIALSHAIVTATNHVRSDGSTYHYVTYDEKTGDGSFQGKSRESTWSRGQAWAIYGFLTCYKYTRDEQFLDVTLRLTSYFVKHLNEKSFIPNWDFIVKGDSISVKDTSAAAIFSSALIDLMEILYKLNLKLEEVKKFEKILKTILQKLYNYHLNKDTNANSVYLLNNGIDNFNKHLKNHGLIYGDYYFLEAISKLKESKSNFLLEVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Q0</accession>
    <name>A0AAD5U5Q0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Stromal cell-derived factor 2-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SDF2L1</name>
        <name evidence="5" type="ORF">HK099_006909</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000063">
        <property type="protein sequence ID" value="KAJ3225368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Q0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23279">
        <property type="entry name" value="beta-trefoil_MIR_SDF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809:SF2">
        <property type="entry name" value="GH21273P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809">
        <property type="entry name" value="STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042293029" evidence="3">
        <location>
            <begin position="20"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="4">
        <location>
            <begin position="31"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="4">
        <location>
            <begin position="94"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="4">
        <location>
            <begin position="148"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="213" mass="24473" checksum="311CE2FFF9131B20" modified="2024-05-29" version="1">MKQIQIIFLFIFLYTTIKGSSKEDFIIEEEFKYVTCGSTIKLTHKPTGFKLHSHSITYGSGSGQQSVTAISSADDVNSYWIVEGAFGKERCVRGEAIKCNQHIRVNHLQTKKHLHSHAHVAPLSSEQEVSAYEHTNIEDNFMLRCLKKNVVYWERESEVRLQHVQSSKYLSSNQNHQYRHPIPGQLEVCGTSRQSENEIWIAQEGIYFSTSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Y9</accession>
    <name>A0AAD5U5Y9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002112</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000168">
        <property type="protein sequence ID" value="KAJ3222600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="637"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="700"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="701"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1502" mass="170829" checksum="078A631B0516BF0B" modified="2024-05-29" version="1">MSNPSNPNSPSLLEMEAQSSSNVTSTSPLNNKLRYESVRTVMLTIFRFIKLIVECKEKTDFKLAKISKFEKLENQLHKVVNYKKRNSVTPSARNAAKKNQNYSFITNKFNVPKFLIIFVHICLLIITILTVKFNYFSAKVDGFSSVESIGCFESVTVETSTSFFEDTFPVRCASQCSNARAITRKFVGGKQVQYQPFIVGSEESGYRADTWICMAALQQKLINHFNGGCVVATVKNSFASQTFNSSVENANVKVTNFDSTYPLSLSLSSPSEAEFCEDKFYYAIPFFIVGLIILPFLKCSKSHFYWSNLFWISVYFVFVSPFISKSSYNIGQLTGLIIPLFSVLFVIYRWISKFSLPTPADFPIDLALFWLLPMWIGIHIDTIEGYLPPFSSFSFSSKMFRADNMIPLILIIGVVLSVIFYFFYLHRKNGTLFTICARITIFFVIYISFAKLLGLVLHLHHYVLALFLVSLTKIQARFSLIIQGIFLGFFLSGILSWGFDSFLETNFESDLGNGFLFGSSIPTWNLNFTNLHENKMIEWNYEFNQTTNITSLYQDDLVNVLGYDSAARFAVTEYVLMMNDIKVYQGKKNYFQLKNSQELPFKVEGSDLPFYFRVSTIQNSRTMDFSKQKGKTPITQACDYCRIKKRKCDGAQPRCGNCSVHNNEDCTFKMEVGKRGPKKGNKSALLSRLDHLESLLASKAMDTSQQGQPSNFERASSYGNSNQFDTNSQQQQIQQMQQFYQGANQLAQLQGGSQFYQGNDNNNSPNSTSIDSLLAPVNINLDPLLTLVKHQQNIMQSQQNQFGDLFNISHSTLSPTSVQNSSPAIPNKGDQFSELQKILIEQCWFKTTVSMVPIFEKKEFFERLRQTEKTGEGYSDPSKSIPFPQYLLDAICAFGAVRSKHRLLYTPDYGGSPIKASELFATSAVEALKGISMNEHYSTECLQTMSLLSYYFFHVGAQDKGFYWMVETYKAAQVFNWDIPSEPYEEKFHPLMNLNPSGKKDRRCVWAIFILQSTFGSRPLLCNERDHLYMTDPSEWEALGFPTEDTGEWHGVRNANRMAIMMQLVFLYRRVIRYCADKQATATTPVLPARKAVLDAIPFVQISDIHRSLLVWHENIPSANRAFNSLTDFIQGSQKMKDNEDWVQKFCNLQVASTYLLALAKIHHHNSKSAQPTGKFQFSTNHLLVGTSLDMILVCIRAFASLMVVPQSSKLEEDSEYKMFYSRLSLDTIMAIALSEVIEFALDCIHQRKGWAAVIDRRQNEANPLIRKYYDKLSPIINDVVERVEKERRDFAIKLNSDNSKVTYPILATDVFINNDITNKNSEITINQSIETIKHPQILSPYKELKMSPIMCNFAVDLTSGVHRPLFSSLEQSYPTSNFTPQQLCSPNSETQLPSPALTNCLDLDELESMLLDSSTYANISNNSKTSSHSLDLLSVTPPPLLINNEYTFKLLNNTTSKANFCEVSKNTFPYSYNYSLSNTPSYTNTQTIADDVRNLTDTLYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U653</accession>
    <name>A0AAD5U653_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006261</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000053">
        <property type="protein sequence ID" value="KAJ3225761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U653"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="158" mass="18706" checksum="190E50F129FBE95D" modified="2024-05-29" version="1">MRERLKDSNIKSLEERRALRRNHQAQQNKLAREDKINENRNSFWFKQMLEKRYKELNLDPSGFMDPLLSQQIEDQLYLEQFFDFESDPNEFENELLSGVFENSVSTIVDCIVCKRGEMKSEVNLISCSNCALKLNTCSNFNNAHELMHYLTQVYSNHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6B2</accession>
    <name>A0AAD5U6B2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="1991"/>
            <end position="2062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="78"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="369"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="941"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="985"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1087"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1528"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="450"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1087"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1113"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1177"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1206"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1220"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1246"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1289"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1364"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1392"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1414"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1460"/>
            <end position="1493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2062" mass="229220" checksum="887CBDC31907FA0F" modified="2024-05-29" version="1">MDASEETSIFLPNSKMSSLHQINRSLKNVASGESLPGLPTKLSSQKSLQDDGNRIIDECIDEKEKNEFESGLNVLSKSKPASVYNSGKPSSRSLNKEPAENADSLDPKIINKPQSSLSLKEDVHAKTLSNNNSVILDENKSDFNAESGNKVGSTLSLVNKEKSVHSLRDDHLGVTPHSTHSIKGLDSKTHSMHSLKESRIQSTNDFDTTPNSIAVGDQSNEMDEKHKKSDSRFLVKTGSDVSAKDYHTSSQKSLKNIEDDMNFCNAKMQGNIKNPSLHSFKDIEGNNVLIQASNESGAKLLQSKKQSLISLNDVALKESHSFGSIKESLTNKKNSNNNIQNNGSQSNNSFQEIGKNELDEAENYVKDVPEESTQMKPSSQKEINSHIKPGMESKQTSSYSQRQQSHHSVYQSDMQPNFETDISSEPLIEKKRSSYSDSTEIDFSNNARESISQLSKKSQSFQSDKNPSIQSFENIPSQNSLKNLKNTTKSSLSFAEEKTSENQENFGIKTEEFCRASSSFSEVKKLEEASCLNKVPSEKSFKERSRPRSAASVKHFGSSHHSGYSLQNLIPKSHSQQSMNGVDSILKSTNSFKEFGSEVLSSKTLDESRNDAVNQQSVSQAFSVHEHNLSDEAVTRHENEVTRQPSLHSKNNSIILSSPAVKSELKNSCLEEKIIFEPASTFTPMTEEKLMNDIVATDNYNLDEGDIEETEENNIMYNTNIEQIQLYLDSMLKEEEDAYSNILPSEEDNRLNQPVSQKKNDLFKGCRKISTNFNPRITGGDFDKYPVIENLRSRLLTERQLNTDHMNELLMLRLANPWSEIQNSSLAILGRLQLGDKTILNPENLQHKLDKAPYIDRDIKWHPKSISLPEDRALYYKRLSAPHPKRPFSPFPEGFLRRCDLTKGRAVDYERCCKLSKPKTVWKYQKPVDLDIVTLMQEEKYRSDAEKRKQVSRQQRKKIDTENYNEDQEAECEPPIVKIRTANTEFESPNAISRHSKAALVQKEKNTTHSTSKHSKAASSTKPLTPSKKEINLEIEKEETVELENHNELNLKTSLVSSSKQIFKAESIGGIVESSDTVVIPNVSKLSSKQHSVTGVNSKPHSKQISKTQSLKESSEDSKKFGSQHESKANSKVTSVTELKPLSRQISEVPTKEKMELNEIVQDEFDGKAPPATEVPLKSQSKPLSKSTSLRENTEAMEPATHKNASKLSSKAPSVTEVTLKSQSKQLSKAASLKEDTEAMEPASLKNASKLNSKAPSVTEVTSKQQSKQLSKAASLKEDAEAMEPASLKNASKLNSKAPSVTDVTSKPPSKQMSKTPSLKETSTKIETATSNNVSKLNSNVPSVAQSKQNSKAPSVHEIETSNEKNVVSQTALKINSRAQSVNKIASSKAVSKNPSKQQSKQNSKISIKECTDVVSQQEPVSQKPFNSKTSSTKEFPSKTTSKIFSNPQSKKISKEPSRQENVSAAISNERSTPGEASSSKHSKGTSKALSRQISKTLSLQNNAVGVVERDKSVILKTKNSNLNSKVASTVELTSSKPGSKTNSTQSSKRVSKTPSVANVAKSTVELPKNSSKTLLVNEASLSKKNSQVISKAASVESVAAEMKASDKEKIEEHHEKFVELTDEEELELKIQEDKKLEENFNKISILANEGDPAAIREKANYLCEGKGNVTVDFESAKELYIKAAALNDNESMRLLGLLYQNGIGTQKDVAEALKWFTQAYECGNIQATMNIGDLYAEGCEELDKDAEMGLTWYEKGANAGLTNAMVRIGVLYLTGELGDEEESAEQANKWINKAKTFSNNDAEVIRTNGLLLVKSGIRKFHEAIDSGASNSYDSCFTTAIEQEANVKGRAEIATIIANSLKDILDEDDDIMSAKETEIFSKKILNYYELAIEQRKEISKESDKLSALLIRSAELFWKRLQDYETAGSRYKEVLQVKYKPSYIPYGEFLLHATNDIEGALSWFKIAMEANVSGAKEKYLELKKKQEQKETVWIEVKKMDGSSIRLEVETGESVLNVKKMLERSIGMAIEEQLLIVGETELQDERNIKDYDVKMDCTVYLVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6C8</accession>
    <name>A0AAD5U6C8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Guanine nucleotide-binding protein-like 3-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GNL3L</name>
        <name evidence="8" type="ORF">HK099_003292</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000218">
        <property type="protein sequence ID" value="KAJ3221636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6C8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04178">
        <property type="entry name" value="Nucleostemin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000002">
        <property type="entry name" value="Guanine nucleotide-binding protein-like 3 (nucleolar)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000493">
        <property type="entry name" value="Guanine nucleotide-binding protein-like 3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF30">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="41"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="380"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="385"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="417" mass="46966" checksum="A93465227784F76F" modified="2024-05-29" version="1">MSEALEKQEEFELKFQEDQSEESEQQESSVGKKDDSRKAYFKEFKKVVEESDVILEILDCRDPLGGRTKQIEEMILNSGINKRIILILNKIDLVPRETVEQWLKYLRNEFPTIAFKASTQNQKNLSHNKVSTKHASSALLSSSECLGADTLLKLLKNYCRNNQIKTSITVGVVGFPNVGKSSVINSLKRQRVCSVGSTPGITKSNQEIHLDKNIKLLDSPGIVFSKAKNAKEAAEAILRNSIKVELVDDPVTPVELILTRCKKEHLMVLYNIPYFDTVQDFLIQIAKQKGRIRKGGIPDLENSARCVLQDWNQGKIPYFTTPPKDSGAHVESLREHSLVDSWSKEFEIDGVIKVEKEVVLNGVKSRSDIATPLFGIQSSGIVDLPMDEGNSEDEDMEDDESEEDSDEDDEDENMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6S5</accession>
    <name>A0AAD5U6S5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6S5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="202" mass="22623" checksum="CB7C5EC8E7EBF57D" modified="2024-05-29" version="1">MSTTTTRNGNEDVENIYTQSEISNAFLSYQYIGNDSDSRSFISSTVSPKDEFATSHESYEAEQLFKLAEKIVNAKEEAEIKQNVLKKHPSWATVNIKGDVKHLYGIAESQGSSFQYTTREQIFQPRQNQAYQYSFENISQTSGSRSNISFLPTATSPLRNPVIMIDKNSSHKVSAFAKEMFGWVLVQVNTAVGEDGVGLRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U797</accession>
    <name>A0AAD5U797_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000059">
        <property type="protein sequence ID" value="KAJ3225522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U797"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="480"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="518"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="559"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="617"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="651"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="697"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="746"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="808"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="302"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="847" mass="96571" checksum="ACD3A502ACFC2A7D" modified="2024-05-29" version="1" fragment="single">LKELQEVIRNLQQNRVKFENDLDYFDVKLKLENIEEKLLPTLSRIKKKVEKPDNSDKEFFDSSHESSQFNDINYWKPAKQPIVALTNNNLKKYLKKNTAIEEEEVDAADDICVDRIQSLFDRLKLLESAVFKDMNERLEKKLDLTVELKGDFISKSCLLEKDSKTINTQTNVMNVQANQINVIKNNQVNHSTTVVNNNVMVASISSPKKIETKSPVNNSVTSNTTTIVNNVVTNNLIVTNLSAPVQKTETNIPVNNFVTSSTLNPPIQFSQKINYYPLNTSLAPNSYFNKTDTPTIDVSNRLENIAAKYKVEEQVILNLQNQVKEAQLKNNQMFGEKRTLPSYVGFGPGPSSIPYLTPGFRPPVNYSPTPQSLVHIYKTETLLNQNVDQPPPKENKEIEEISFHQNKKTFNKLEDKDFNKKTELDLKKKKKQENLNPSHLPIQHDETAIQLSQDNLFIVENLYEDKKINKILKKSLSKTIFIYFNLIRACITSILTIMEAKRALSDVTYNSFNANWLMIATIVFASVDFFVAFIKAFPKSFWFCWDIKEFDPYSGKKSVFALIADHELLTDVIPLLLNIVVKIYTTRLHEVMSDPDATNIHDFSRLRNFNDPKNKNFYLLSSFTICLFLTILFHTTKIAKVLIIEKKSNILAILVIFKGILLCYDIGVSGFFLYQVLISLGPNLMYSSTLTSLTLSVVIPAPVVSLFTNAFINLPLHYYFVSLLLKNSKKKNSIFSKLAFSANRAFHPLLESIFGTYSIWMVFATFYVLKSIRGVEIFSTNGLDIKSLISEELKFKDVLVGLVITNLVINYVVGVVCCLGYWSFVILKGIFGGDKGIRWFKKKSGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7A9</accession>
    <name>A0AAD5U7A9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger MYND domain-containing protein 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ZMYND12</name>
        <name evidence="7" type="ORF">HK099_002645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7A9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053248">
        <property type="entry name" value="Zinc_finger_MYND_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46533">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46533:SF1">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="37"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="363"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="44894" checksum="4F8C30E79D5496F0" modified="2024-05-29" version="1">MSVQIGISETFPKTTQLVQRGKAINPLSNPKGQKFECELCGKPAYIQCKNCRLTYYCDKDHETIDFRGIHEKICQLIIPLRTPLGDFGSEEERAYREKQTRIRQMNLLEITKIEAHKKLFESQFDLAIPAALQALRFSMDVYGQDSIELVPSYLLLGEASIGLKQFSQAEDYLSLAKWAVLKADSACHPSIRAQLHRNLGLMFSSQGNYDAALLQLANDIFFSSIAKSPDHITTSGGYFQLGNVFQKLGRLEDATATFDKVISIWKLFLKEKTKFLNEAQQAEAVQILTTIHSFRSVHMNSSVTSAAEVMYVLAQLYNTCNKFDKAKACAERALETYESALGRDHSMTVEVKIFYKGIVVDDKDSSPSSRIQSANSKSRKHSINGMMRRTSSVNSASPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7L4</accession>
    <name>A0AAD5U7L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bromodomain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002424</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7L4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="106"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="249"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="6">
        <location>
            <begin position="437"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="390"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="514"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="593"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="802"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="624"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="537"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="600"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="823" mass="94666" checksum="AD668CD41534AC5A" modified="2024-05-29" version="1">MTTTESIHTSIESKLVNDPIEIQLDQLKPVSQQSIDTESPSITSNSEANTQQQSNVEQISSKCEEVSQASNQSNNVIQEENLTSITNPLLHAQQIKTLKTICKYLKKTKGAENFSKPVDPVALGIPQYFEIISNPMDLDWKEFVADMDLMVQNCITFNSRENVYSQIALTLQANMHKHLEKLPKEYKKRGSEVKLEPIHSRSDNPRPKRETHAPARVEFGDNLSPGRKQRKHLPEFKFCNSVWRELTNKKYPFHLPFLEPVDTQLVPSYSKIIQHPMDLTTIKKKLDSDIYNSCEEFEADVRLIFKNCFQFNLVGDSIHTMGRQLEQVFNSKWAEKPYEFPAPAAKSLTRKYRDDSDNEYDSAEDRNLLMQMELDKKKVELQITNLKISMEKRRKRRDERMQQARKRPQTNGSQNNRKRGKRQKRIKSFESEDEEIKSLAMDEVPVLTSDQQMKLSLGINKFDDVTLQRVLQIIKESTKYRNLDEAQGEIEIDLATMDVRTQFRLYTLMLSKESQSTKRSYKRRPDTGVTNALGAISHGESSSGESSDGSSSDSGSVSSGDSLFNNKNKKKKGVVSKQSTIFHVAESQMKVNETKKQLGRKTSNINQQDDFNLPFKSHSTIPIKSTIELQKEKELEALEEEKEKKKKIIENQKLKKKNSSLREKSLLDSIYQAFDGLEEATSPAAANSTSTSTPVSPNKTEKLKNIEKVADKGMPITEKEKNFIIEENENLRKIYFNKNKQNYDFEILKKSKKIYLEFGLGNRGGNTNSRLEDELEDEELRLGRELFRENILKERRLRRKKEQEVGGVMNKADNGNLGNERFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7P8</accession>
    <name>A0AAD5U7P8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RSE1/DDB1/CPSF1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000099">
        <property type="protein sequence ID" value="KAJ3224248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7P8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="1">
        <location>
            <begin position="814"/>
            <end position="1125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1144" mass="129068" checksum="B2434A9C683E7035" modified="2024-05-29" version="1">MVLSIQEMNDGKDSDIYVYMKEVVVGLSVKKAHLSMYKTLIFINSQKVLLAIYNKQKQDSFKVIKSYSTTSAISDSAFVKEHLYLLINNNFKILKLVNQDLLLDYETEILNVKNLLKIATNSLETVALTSSNKVLTFLNVESKRLRQIFVKEDIIITEFLSEFTFATHSTSKINIYYIPNDLQDIQILANLEVNSFPLHFIPFNNELTNAKNEEHFLLFSTSEISVFKFNGATLMCVQNLPLDELVSSTLNTAGTIYFASISGNFYKIQKKELLRISPISSKISLVEKRLPVKSMLLLENEVNMEKSEELQTLILFGDNCDSEIIEITRNTLSSEILLTKKIKTIQNWAPVIDFKLCDLYNEGKDTMFFTSNVSYTNSPINCKGNSRGGAIREVKNGISVKGEVIHNTTGALNFWALGGQSDQLNDSYLAITFPFETRLMILKKTLKFENENFEESGGYHFEDISVKSAIVREQHTLFFGNLTFENDSSDTYLVQVCCQGVYVTCQNSHMSGCYISGKNVVQWISPANTLLLHCSCIKNCLLIISKNLLTGENLLLKLLVRKNINNVFYIDLIQQFSLNEEPSCCNILNSSKNDTALVAVGTYKPSLVLLSLEINDEVNSINILHTEDFPFSFSKNNIGLDIPNSVCFYQEFENGSSKNYIIVGLRDGNLLLFSLNENNIKFIHKIGFGILPVVLIDYKTPNDANINILCFSNRSARIFIKRGRLLLTSLAYPSISLAKPFNLPFGKNSLGIAQHFLAISSENALLNLQINKEKSIDFRMKIIGETPRRILYDHCTGKLIVSTTFKDDGGGCFSEIKIIDPLTGKIIQKECLPKNEVFWDIKKEKRYICIGTFGYRKGVETGMESGKEMGRVLVYNLKQNEKKSVSSTDNTDANSKLKFRRLGEFKCNNSIFSVVSYLNGLISGAQIKMRSDIHSLSTNGDKIIVGSERESISFYTLDPKTKKFEFLASDRQPRYTVDCFSIRDNLAVGSDKDGNFFGFTCKNKSMKDFSTPSKIEKTLENSFLINVGQVVVKIQKGNLVHPNDTFNFDFHEKFLNKDINLGWKDTFINDEALKSVDTDFSSISISRNSSTSNAILYGSTMLGSIFAFVEISKESYKKLIILQGCLMLNSSTRPLFGETKKIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U801</accession>
    <name>A0AAD5U801_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U801"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018788">
        <property type="entry name" value="Proteasome_assmbl_chp_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053720">
        <property type="entry name" value="Psm_Assembly_Chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31051:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10178">
        <property type="entry name" value="PAC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17651" checksum="68F20E1BF6A02270" modified="2024-05-29" version="1">MSSVENNDGSFPLKTKTLSRNFKNKNLSILFNEFNDKLFLLISNYNKVGTFILTNRSGVLNNLDFYVEKFDKNDDSMTFEHKILLGSRESINLPSIYSSFILEKIIKKNENETRPILLGLSLDSKLLGTEVDIDLNREYLSEIESMLMELQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U808</accession>
    <name>A0AAD5U808_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Isoleucine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Probable isoleucine--tRNA ligase, cytoplasmic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ILS1</name>
        <name evidence="18" type="ORF">HK099_001444</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000140">
        <property type="protein sequence ID" value="KAJ3223193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U808"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00818">
        <property type="entry name" value="IleRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000004">
        <property type="entry name" value="Isoleucyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000023">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000050">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19302">
        <property type="entry name" value="DUF5915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="16">
        <location>
            <begin position="21"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="17">
        <location>
            <begin position="680"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1059"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1066"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3223193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1113" mass="128092" checksum="EBED535D7F61C254" modified="2024-05-29" version="1">MASRTIPDIPSNVDFPAEERKILEFWKEIDAFQTSLKLSEGRPPFSFYDGPPFATGLPHYGHLLAGTIKDVVTRYAHQTGHYVERRFGWDCHGVPIEFEIDKKLGITGPQDVHKMGIANYNQACRDIVMRYASEWERTVTRIGRWIDFRNDYKTLNLPFMESVWWVFKQLFDKNQVYRGFRILPYSTGCTTTISNFEANQNYKDVIDPAIVVSFPLVDDPTTAFLAWTTTPWTLPSNLALTVNPDLEYIKIRDEESGSIWILCSERLDIIYKDPKKAKYAVLEKYKGVELRGIAYVPPFDFFKDRRASGAFVVTVDGYVTNDSGTGVVHSSPAFGEDDLRVCVEQKVVTGENDLPCPINEKGEFTNEVPAYAGVYHKTADKQIQKDLKERGRLIRQTQSSHSYPFCWRSDTPLIKKAVPGWFVRVSNINDKLLKNNKDSYWVPEHVQEKRFANWIKDARDWNISRTRFWGTPIPLWVSEDFSEVVAVGSVAELRKLSGCGELNDIHRDKIDHITIPSKCGNGVLRRVDEVFDCWFESGSMPYAQQHYPFENKDKFEKTFPANFIAEGLDQTRGWFYTLLVIATHLFDKPPFQNLIVNGLVLASDGKKMSKRLQNYPDPSLILEKYGADVLSYRLYLVNSPVVRGEPLRFKEEGVKELIAKEHNFDFMVEETRSKSTNVMDRWVLATLQSLIKFVRQEMAAYRLYTVVPRLLRLIDDLTNWYIRFNRKRLKGENGVEDAVHALSTLHEVLFSLSKMMAPFTPFLSETMYQNLRQVMAETKEDTRSVHFLMFPEVKEAEYDAVIERQVSRMQTVIDLGRFIREKKTLSLKTPLRQIVLINSDPEFHSDIKSLENYIYEELNIREIVVTSDEEKYGVKYKLEPDQKVLGAKLKKEFGKVRAGLSKLTEKDAKEFAKHKKLVVAGVTLTEEDLKIIKFVDAKDSTFEAHFDTNVIVLLDTVLDQSLIDEGIAREVMNRVQKLRKKAGLQPIDDVNYHYEINKDEKGELENAFKSQVAYLSKSLKQDLILGKPKGKLVIEEDLHCLAGLMGVRDFASQNGRCLGKGEDRSNQQWTPRLSDCQNNETTDSPSRKRVIVGEVLAVFLIEKSFCFKFNNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U809</accession>
    <name>A0AAD5U809_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="3">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">STT4</name>
        <name evidence="11" type="ORF">HK099_004600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05167">
        <property type="entry name" value="PI4Kc_III_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.70:FF:000011">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000012">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000014">
        <property type="entry name" value="Phosphatidylinositol 4-kinase STT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019138">
        <property type="entry name" value="De-etiolated_protein_1_Det1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045495">
        <property type="entry name" value="PI4K_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF15">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09737">
        <property type="entry name" value="Det1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19274">
        <property type="entry name" value="PI4K_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="10">
        <location>
            <begin position="1186"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="1457"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3226573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1733" mass="198645" checksum="82F5DA9E412E666B" modified="2024-05-29" version="1">MLQIKDGNFFEVRTIGYHNNEDDDFVLAKLRDQEEKHRLSLRKIAQPRRSSRFSLKSEKDQVVQSEDSEASPVSMQDEPTLCGLKQRLMTFLYRKALVSGSAKYIFIHDTLALILIYWTLSQLAHFALTFDLFASLVMWRVHFLDEAHLMFKFGTIDNIMYRNNPEPVRLTPQASIQEKVDPLLQISNRLDSNLSFNKNSDYEEPNFIENVLSLASTLFVDAKISRENAECVKLFLDYFLSILENSFELKCDEDCTDIWDSLLKDQKNVTLKHVDPVLVDYIFDVCWKTEWKEKIQIYWKEDLYLEYLSVILKLRIYCSFHKIDVLTVIYNEFSDMFKSFKKLYEDNHPIGVILHIVEALGIFAQRFAIIDRDEELLTTTIQLFLNFLTEPADCFMVFSQDDTESVIQCVCVILSTICQNSGNSAVSKSALFTLINIAQSGKLLTTGTNEKNSYLRLRNSFTGISFIAPTLKTKDAVIVFPVFSKYLEESDRQYDELIWEALGNIALLTDDISIYDEVVTLVLERCRKSFIKLTRISRTLARVTGKPAAFRDLYLRKIIALLIDRAETSLKQTDTSSLDEVKEVAYILKYLCDQIATEMDPQKFTSSLEDKYLVIFRNLWIYIIVTILPNLNGSWTKDWTHILSSVAAVTPALLLTKDKKQLEADLLSNSAVGVIKLTEPAMTKLRGTLLGLLPSKTNEVKGLSPALTIYLLAVYNLELFRVWRKFNVDYVLQYTTDDRNSDAADLLESIADEILKFHLTEKSLKHDVNSIQSHLKSLIKNSAHFMIRVRRFCSAKIDEVIAEDQKRACEDFRKLSERWLFTGLNSCPKEIGGLFQSYTSQRFLELFTFITPDDSNLASLFKSFYSNQAFASSLVSSLIKQGHYIGEIRGMIELTKSGDSFDERREAIRSVAEKMKLNLKNITSSKNFFNIEKFTEEYSGCLHRAGAVLLLEQMDDPELLSLICNTNVLTRFNIPLIETSVSVWSWVMSSDPSVAPKLFAKLIGLWEFSAIKRLGLYEKNSEVGPFYSKFTYSPSVTPSDEDDPSLGHLVWIEFLHERLLVLEHGEKGVVDLLVQLVSVFHSHMDKISVRKIGRCGESWVQKTDRKCENFIICCPAMCLKKNPPFTIKSSRLDLKVGRNMVLSLKIKFFVVELQEVQNLLKILMENELNRAITWANEPNSVFIQENLANSYTPAKWASVYKTAWAINPSVAMHLSYRYIHTSDIAAKELADLIICNPTKALHSPYGVSHLISKSGNELRFLLMWAPISPVEAVCLLGPNSSMHPWIVQYAIRVLEFFEVEQVFFYIPQIVQSLRYDTFGYIEKYVLETARSSQLFAHQIIWNMNANMYRDEEQQIEDPLKPTLDRIIKKIKDAVSGADREFFEREFGFFSQVTGISGALKQYLHCSKQEKKMRIDEEMAKIKVDVGVYLPSNPESIVVGIDYHSGRPLQSHAKTPFMATFQIKKATEKYTKRMSILSQTDKSVTKDAVWQQCIFKVGDDCRQDILALQLISIFKCIFEKAGLDMYLFPYRIVATNPGCGVIEVIPNSISRDQMGREKVNSLYEYFVAHFGTPNGMNYQQAQLEFLKSLAPYSLIIYLLQIKDRHNGNIMFDSQGHIIHIDFGFILDLYVGGVNFESAPFKLTTEMIQVLGGDSSSPAYQRFSDLIVKAYLACRPYANEIISMVSLMADSGLPPFKGGSTIERLRERFQLEKTEKLAAEFMILKIKESHENTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U829</accession>
    <name>A0AAD5U829_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U829"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041646">
        <property type="entry name" value="VC0807_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="27751" checksum="4A7DF07ADAD650B1" modified="2024-05-29" version="1">MTQSMNKQEFNLTSDSSSSSLHTNEPQPPRKNSIRIVILRMILMNFVFPAIIFNVATNYTTDVVALILSAIPPFLETIFVMITKKHVDLVSMLVLFSIAAGVIVTLCTNNPVLLLIKDSCLTAFFGTAFLISLLFPINLIWIYNRSFQNTKEDLARLDEEWLKPGVQRVTRICCLVWGLGLLSEAVIRILIILFAKIDFKVLANLSLAFPFVFTGLLAIWNYLYILYLKKKYPPKTTIGSEASSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8E8</accession>
    <name>A0AAD5U8E8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NGG1</name>
        <name evidence="8" type="ORF">HK099_005229</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8E8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019340">
        <property type="entry name" value="Histone_AcTrfase_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10198">
        <property type="entry name" value="Ada3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="668"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3228219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="741" mass="86094" checksum="230F1DF0B8D42656" modified="2024-05-29" version="1">MSIAKSIESKLSLQLRPSFLEIVDDSASHAGHAAMKGLKAKETHFQVKIVSDKFLNLSKLKRHRMVYGILDEEFKNELIDIEEMNFTEFLISDVSAEKCYHKYKSPSTLLPKPEELKEIKKELLDVLKTTQLTGEILIKNQKIFNDWKNNSSSTAATLSNSSSFQNNSNEKLKLEPVDSKVNRKRSHSIEDKVNGKFLILTIIRKFYEFYATLILEEAVISRTDGTNRISLYQKEGFIRVGIAKLEKPSPPPHSPSASTNAKISSVGKKDTQLLLKKRKVESESLSANSTPPSSVLLYEEVSMDMKNMSGDYSKAKAQNQIPLNTFIAYTDQYFRNLTEEDLKWLDRKDDEVTPYIIPESNKKHYLDQWASQDKSHSEVLQKVFHNSDLGEEADTVYPGDIYFGSLSERILSSLLEEGIVENHFEDEQDVADNTILRKEERTYEDVNMFEERVRNELKYIGLISENEDDERHMDNDEISVELRQKQAELRKQVKINNKRKCKLYEVSKNFMAYQEFLAVLDETDKTIEAAYSRRFKAVKKQKKKLTKEARPVSESVLNEIEKRKTWLSELAQQDVAILRKKQQILEQNKIKKGFGKLKEKALETEPSFIKEIFFDGADVKSPKNFFTNNNSKKNKSLDLVKETSINSMFLKAKSEQKSKKKNFKRDPYKKITDERKKLREERIKKNEEYLKNKQEREKQHLLNVQKNKEKKFKLMKKTKKGQLVLSGTIEHLLEKIKKNEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8U1</accession>
    <name>A0AAD5U8U1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPB1_1</name>
        <name evidence="8" type="ORF">HK099_000282</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8U1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF63">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="7">
        <location>
            <begin position="83"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3224070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="452" mass="51630" checksum="17EEC3FA1337F887" modified="2024-05-29" version="1">MEFFLLTDSQRKDMADYVISSERGLQDEKGDLYNSYCEICNTYDCHGHLGFLDLKHAYICGRCLKLSRYPLFTVLDNPELGLSKYLMRSMLVPPASIRSKDNGEWRTKLYKLYKKLLHDIKIDKYSTVAADIRKIYGLSKGDSLLLFMSGKSGIIRKICYGKRIENSARSVITGNPSIDIDQVLIPREIADILYKKHILTGNEKDLSKYFIVKDSPLEKFQAIAGLEVFRHLEDDDLVFLNRQPTLSYQSMLSFRAKIRTDNIKTIGIHPNVTKTFGADFDGDEMNIYVFFSEEDSKKCHVLNFPECINKIQDEKTFEHLGLNSYKELDNWGLTVNIDDIAAKKYNNTGLEAMIESGAKGSIKNFDQMTNKLGDQFVLGKKVGHIENSYYSGLSIDEYIIHQMAAREGIVTQGVSTSETGYINRKGCHTFADVYQKNNIIEDEFGYISFLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8X8</accession>
    <name>A0AAD5U8X8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8X8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="75" mass="8359" checksum="9CD6DA65851C2BC7" modified="2024-05-29" version="1">MKELKKVNAISIWKTASNVITSNVGSFSDGSSSCSIEGKTRSEFSLQNMKENLKRELKEEMSRELNALMASLCKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB56</accession>
    <name>A0AAD5UB56_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase</fullName>
            <ecNumber evidence="4">1.1.1.302</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_007837</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27274"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27278"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HTP reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB56"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050765">
        <property type="entry name" value="Riboflavin_Biosynth_HTPR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011:SF7">
        <property type="entry name" value="2,5-DIAMINO-6-RIBOSYLAMINO-4(3H)-PYRIMIDINONE 5'-PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_8G06820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="13">
        <location>
            <begin position="53"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3227968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="301" mass="34301" checksum="E04C6B8715DBD220" modified="2024-05-29" version="1">MIGLFEKIPTIESIKDFYSIDNLNSYTDRPYSWSNTVCTLDGVINLNEDLTSIGGGIALKHVPQLGYLSEADFRILNAGWAFSDAVLITGKILRDEIDAICKIEFEDLTNLRLQIGKKTLQPLRLVLSSSGHIFNIRQDSTSIDSKFFENVTSKIIILTTKKGSDYLSTLRLDYKFNFEWNSNVEIVIFDDDQLDNGKESIDLRKMLKLLKIRFKIDYLDVSSGGTVIQQFRDLNVVDELRMTISPQIVGIKNSLGVDRPTIFPSTCKSYNCNNSPLLTWKGIRLLGERMIFLRGIYQYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBD7</accession>
    <name>A0AAD5UBD7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005223</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBD7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF22">
        <property type="entry name" value="VERY LONG-CHAIN ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="39"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3228213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="290" mass="32643" checksum="3676D80913F20CEF" modified="2024-05-29" version="1">MSDLLHDLNLVRKLLPDIVRSKYYIRAKKGNFIDLWLTTVQNFQDKECLVMGKKSLSFNDVDRVSNQIANYLLSLGIKPKDTVCIMMENSPEFICTILGVAKVGAIGALLNYNLRVNPVLVIFENPFSSAIQSIHSNLKQTFENLQFTLFNTENDLFNEEGFLINSFLSNKILKSISSRPVKEELRINSHFGEPYMYIYTSGTTGLPKAAVVPHAKAFSAAFLYSSNFSVQSTDRIYNCLPLYHSSGLLIGFGFTVRNGSTMIISKKFSATSFWKECCESKATVVMVNPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBF2</accession>
    <name>A0AAD5UBF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcription factor IIIC 90kDa subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBF2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044230">
        <property type="entry name" value="GTF3C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024761">
        <property type="entry name" value="TFIIIC_delta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15496">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12657">
        <property type="entry name" value="TFIIIC_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor IIIC 90kDa subunit N-terminal" evidence="1">
        <location>
            <begin position="18"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="463" mass="52595" checksum="1F688772510CE53F" modified="2024-05-29" version="1">MGTEDVHDYRREMLEKESFHQVDWSPSGCTKRNSCLLIVVSGSSKVYIFGPTNDPYVSKWDKIHDLSVLLVKHYICNENNVTVSKKYVDKVETMSACWSDTFQPALITTSTLSSLMATGSKNGSIVIWRIISEFQAFDDSWVILMDFSKWIKDNDEAHHNGCVKSFLFKLSFKSDGAIGCEVSLYEEICGGDLRNCQSLLFYKCPYNETAPLCAISKGSRLFVWSTSGNSKTGNSFGTVSSLKIPSNFGTGGLVWGASPDELRVYTIDGKAFKVEVSSRRLKLLLDFTEALRNQAVIFKEHCFVNEEDHDTQDNKKNNYTKDIRIYGVFTTFNCLTDFVLFQVGASSELYYNIAKFDESFFFPLPMHSNNDLSLESFLFERFKKLIHQKQLTESYSPSHLFWDIIIYSQNDANTLVGEAESFFYRFMSILMKGYVDSSAVVEEIVAEENTIGNNYGGHSSWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBK5</accession>
    <name>A0AAD5UBK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphotransferase</fullName>
            <ecNumber evidence="11">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GLK1</name>
        <name evidence="14" type="ORF">HK099_001431</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16126"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22740"/>
            <dbReference type="ChEBI" id="CHEBI:4194"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:229467"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:22741"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JADGJW010000014">
        <property type="protein sequence ID" value="KAJ3227582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBK5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24018">
        <property type="entry name" value="ASKHA_NBD_HK_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.367.20:FF:000020">
        <property type="entry name" value="Hexokinase-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF16">
        <property type="entry name" value="HEXOKINASE TYPE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="12">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="13">
        <location>
            <begin position="139"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3227582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="393" mass="43949" checksum="CAB57CD6BF76FA3D" modified="2024-05-29" version="1">MWFLVCSKLKKGLTSDEYDLKMIPSYIQFLPTGEETGTYLALDLGGTNLRVCQVYLKGKGVIKMKQKKFKISDEIKKASGTHLFDFVADCIKIFLDEYNLSNDNLKMGFTFSFPVEQKSIGSDTVGTLILQAYRDAQTRIGVILGTGTNAAYVENLKNIPKWKGQVPEGGKMIINTEWGAFDNGKKILPITEYDNLVDSSSVAPNSQVFEKMVSGMYLGEIVRFILLDLAKKYNLFGGSSFHLLEKKWSFETSFLSRIERDHSTDLIDTKTILENFFQIYNTSLTDREYVKEICELVGIRAARLTLAGIASILILINRLDGCTVAIDGSVFEHYPHFTSRMRDALLELVGISAENIVFEQVRDGSGQGAALVAACCDTLKTPFVPKDVHKKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSA7</accession>
    <name>A0AAD5XSA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001468">
        <property type="protein sequence ID" value="KAJ3203157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSA7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140268">
        <property type="term" value="C:endoplasmic reticulum-plasma membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120015">
        <property type="term" value="F:sterol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13220">
        <property type="entry name" value="PH-GRAM_GRAMDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRAM" evidence="2">
        <location>
            <begin position="231"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3203157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="353" mass="40602" checksum="EE957AAB293985F7" modified="2024-05-29" version="1" fragment="single">MSAPVFKHSHKLLTTFKPDHATKNVNLMHINNDTRLKNNQNSNLINHFTLPKNNVARRFSNILLKVTTDTDYSTDFLNIPYDISSNDNDTTDNTPVHPFQPSLDVNFEISQNNSDSTKNIRRKSISLPVNEQKKIGELQEEKDALKENLEEKNLLLKEESKTPKSSIEKEGTRSSEKGGNLNNQGDLLGEEVNLRKKSIKTCLNDTHIGLRTSRVFSESNRSLASHEKRNKEVHKLFKNLPEDDYYVDDFKCALQKDILLQGCLFLTERHFCFYAKIFGFVTTLVIPISEVQVIEKKLTLRIPNAISLNTKNSWYFFTSFISRDIAFKKMDTLFREVNDLEDAQSLPNSNLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT17</accession>
    <name>A0AAD5XT17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000980">
        <property type="protein sequence ID" value="KAJ3208722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT17"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3208722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="314" mass="35813" checksum="F7D6FC4521292E3C" modified="2024-05-29" version="1">MSSLENSEENTIDFIDDFDTDDGINETKADVNYTDKNEFDTVHDSNISQNEDLDYHNDFEESDNKETLPHLESSPVEQTFIESNEESTDVTNSSTIKDDIQHNFQPNETPSVLEVKKPRISTISNANSLLHNNRSSQLKVKPTSKKSGTLKSISKTLALEVEVLKENEKVCLNTIKEMKLEESLIAKNLSDIRKRENLIGDKKTKRLLNKQAEAYQFLVHKLEEEIVRLSGFKQKGRDKRHKFPLEQKYDFINDNRLSSSTKVKSLANLEKALSTKSGSFNTRKSGELNFLKNPTVFDNDETTFMGDPVSLIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTQ5</accession>
    <name>A0AAD5XTQ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxisomal targeting signal 1 receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007351</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000701">
        <property type="protein sequence ID" value="KAJ3213529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTQ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005052">
        <property type="term" value="F:peroxisome matrix targeting signal-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3213529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="585" mass="67206" checksum="02844BB9283D66BB" modified="2024-05-29" version="1">MEASCVGESSVQKLGSLINKDKSLYSDNIRNTQSRISDASRKKILQFDSNANNFINQKQIINSNNTPNFLNQNLINQNSLNEKLIPKNVIHINDEWSHEFMKGKHLLNDNARFDLTSGNKQMMESVFQSHFTTPANSNWNTEFQTFQAHHQNLVVLGDAEMEKAFERAQGHSWEQEFITENSWEKEFEKQQLAEAEDWADEKITNDENFTSEALELPQNLANKWAQNFNGTQVKSGEWEEDFLMEQHASSSSNWATEYHESGPEYDWNSRNDNISWVDEFNGISLNAKDETLTWNEEFQNSVTRKGPSNLYPFTKNNLFLNQSIDSLQQLSTKSHLSESILSLEALVQMEPNNAQCWYQLGMKQQENENDHLAVVSLLNALELNPKLLDAWIALAVSYANENSNEGVLESLTKWIENNDLYKNKGNLKNRQYGREGHEFLTKKFLALARERPLEVDADVQDYLLWNKLGATLANSKNSVRSLDAYFNALSINPEFIRARYNLAISCISLQQYTEAAEHLLGGLQIQEQINGADNIGKINGNEDISSLRSDGCWKLLKLICDVQRPELTEACNQRNLNFFRDHFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUV6</accession>
    <name>A0AAD5XUV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005599</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000442">
        <property type="protein sequence ID" value="KAJ3217143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUV6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF15">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="291" mass="33935" checksum="6BD76EDB24DA2527" modified="2024-05-29" version="1" fragment="single">FQEEGYLVIPNFFENYQELLKRSKELLENFDIQTHPKTKFTCKDDNHVGDDYFLNSGDKIRFFFEEDAFDEEGKLKKPKEKSINKIGHGLHYHDKVFKDFTTQEKLKNLAKDIGFKDCRVLQSMVICKQPEIGGEVSPHIDSTFLYTNPPSAIGFWFALEDCTTKNGCMLFAPGTHKRHKVSKRFVRNKESTGTTFLRSTNEDEKKWFGGEFTQIGDEKPEPAEDDYVVAETKAGSLVLIHGEVWHKSTHNFSDKSRFIYTFHMIEGNNEYDEKNWLQPTAEHPFMKLYDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUY4</accession>
    <name>A0AAD5XUY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="13">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="13">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Translation initiation factor eIF3 p33 subunit homolog</fullName>
            <shortName evidence="13">eIF3 p33 homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">CDKL3_2</name>
        <name evidence="13" type="synonym">TIF35</name>
        <name evidence="19" type="ORF">HK099_005473</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000428">
        <property type="protein sequence ID" value="KAJ3217432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000049">
        <property type="entry name" value="cyclin-dependent kinase-like 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF400">
        <property type="entry name" value="KINASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 13" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RRM" evidence="18">
        <location>
            <begin position="179"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="263"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="563"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3217432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="733" mass="82975" checksum="78DDF917755AEBD8" modified="2024-05-29" version="1">MTTLVKSSSNGNWADSVDDVTDDIKSVVEYTTNEKGQKVKITRKIKFTIIKVKASHVVAERKKWKKYGDVKGMMPGPDTKSTSLGEIVHLRMGIKKDEPVVEVESATAKIGKSISCRTCKGDHYTFSCPYKDTLGAAMEEDVEKERTSNQENSGKYVPRHKREGADQKGESMDRRDDYSTIRITNLSGDVQDQDLRDLCSKFGNISRVYVARGHNSSLCKGFAFVSFYDRVSAENALRVLNGKGYGLFKISKYNYKSHLMDAYEKLGSIGEGTYGMVMKCRQRETGQIVAIKKFKESEDDLQIRKTALREVRMLKQLKNDNIVNLLDVFRRKGKLYLVFEHVDHTILEDLDKAPHGLPDDVARGDTVRKNMWQLLKAVDYLHSHNNILVSINGVLKLCDFGFARTLAGPGAKYTDYVATRWYRSPELLVGDTEYGKAVDVWATGCIFAEILTGQPLFPGDTDIDQLYRIIKCLGKLTKRHMEVFLKNPLFVGGRIPEVSKVTPLESKLPHISAEAMSWLRSSLIYDPDQRATTRQLMQHTYFSRDDFVSRYETELKHTIEMERERDQTEKFKRKKPKKHSSYGHNSKKDIRQPFEEIENSKRFHDDEMFRNISTIPPINNQGKPHLLSNYNNIGGGGMTGMGIVNGFNGVMLHGINNTISQNSPTIVNNSLSYSNDKLVPSTPNSNFSKKKPHFSQHTISFPKIGFNTSGFGQSMVRGQGLNGNNSNNDNTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVL1</accession>
    <name>A0AAD5XVL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Subtilisin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000251</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001049">
        <property type="protein sequence ID" value="KAJ3207523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVL1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000016">
        <property type="entry name" value="Proprotein convertase subtilisin/kexin type 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042287776" description="Subtilisin" evidence="7">
        <location>
            <begin position="27"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="40"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="160"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3207523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="44373" checksum="92621E7AF84AE80F" modified="2024-05-29" version="1" fragment="single">MYLNVNINQMLKVFTSALLLSSAVMATPAPAAQPEPLGKWIVKLKQDGNPLKKREFDLSFAQEILSKDNQKPASFVGSPKQEKSEIFHEFDALDSFSGFAFKSSLEAMKEIAQNPRVEYIKRDAKVKIYDSQQNPTWGINRVDQRSLPLDSTYKYPTEAGSGVTVYVIDTGITAQHPEFEGRASEGGSFVNGVIGTSAKDNHGHGTHCAGTVASKTYGVAKKAKVVGLKVLGDDGTGSDAGVIAALNWVAKNGIPNKSVASMSLGPDFETCVEVARPDHPEDEECNSKAVRDAVSSLVKLNIPVVVAAGNDARNACDGAPASEPLAYTVAASTSSDRLASFSNFGTCVDIIAPGQSITSTWLNNRTNTISGTSMACPHVAGGFAVILSKKQYTSYTDAYADMSSAASVNKIKSLNSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW25</accession>
    <name>A0AAD5XW25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional adapter ada2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ADA2_2</name>
        <name evidence="2" type="ORF">HK099_003737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000249">
        <property type="protein sequence ID" value="KAJ3221141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW25"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070461">
        <property type="term" value="C:SAGA-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000087">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF20">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="1">
        <location>
            <begin position="51"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="140" mass="16450" checksum="490A40663B1C5BA1" modified="2024-05-29" version="1">MCSNYTKNPTKLLSKSSRLNLKFKENSPIVQTIARLIAMEKIPEEEEHKAKYLQPQEVKTCLILRLLPSQYLRCKQVLLDTWYEKGPFKKRDAQRLCRIDVNKTARLYDWFQNLGWFSQVEDDKLIDEEIKLGVDISATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWD4</accession>
    <name>A0AAD5XWD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000220">
        <property type="protein sequence ID" value="KAJ3221596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWD4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="22034" checksum="A307CDC6F0FBDEE8" modified="2024-05-29" version="1">MANNLQFEKILMKLKTIGNEIKGLDSLEFEEKCNRDLESSFELKIMQSLFIIVQTNPMVSGNTTEDDLNRNPLQSEKEEHRWIRCANCWENVSVDTLRESFIALTPGTINDETTEFLESLSVGFENMQYTDDLARNELIKCQKWIAEVISWQKANKQLTPVKENLKKSMKSMESWRSIQKRFNIRFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWI6</accession>
    <name>A0AAD5XWI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uracil-DNA glycosylase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007196</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000679">
        <property type="protein sequence ID" value="KAJ3213749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWI6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097510">
        <property type="term" value="P:base-excision repair, AP site formation via deaminated base removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF0">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00987">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="6">
        <location>
            <begin position="80"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3213749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="234" mass="26988" checksum="69972AE171D71F0B" modified="2024-05-29" version="1">MLKYLEKENIVKKNVKDTEQDLEKAVDDKLSGEKADEKQVVSSVKNGEENFIEKELFNEDWYNAKISKVYPPVNEMYSFAKFELSQIKVIILGQDPYHGPNQANGLCFSVKKGIKLPPSLRNIYKELQQDLGWKKIPDHVEEGKANSHVKFGWETFTDNLIKYVNKNFENLVFLLWGGNAIKKSALVNKKKHCVLETSHPSPLSVHRGFFGCKHFSKANEYLISKNKQPIDWKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWU4</accession>
    <name>A0AAD5XWU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TTC16</name>
        <name evidence="1" type="ORF">HK099_002183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000170">
        <property type="protein sequence ID" value="KAJ3222551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWU4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45153">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45153:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="517" mass="60332" checksum="2A05309AA26D272A" modified="2024-05-29" version="1">MNQVIHQSFENNEKGLNLLFNKDKLEKNPTKAQSFFSKSILLHPKEPIFYWHKAESFLESGELTCSIIFFKIAIQKIREFNSTENEGFLDKIQVKIKSEKDNLYLNMRYEKIRRSFKKFSVCLRHELEPTFCADPNASRELNFLKVNFYYNHRAFANIGLKNYEDAIENICLVVLHCPNYLNAIILRARLYMRLEKFDFVNIDLERIVELDSKHFVIKELRDFVIRVAVNYKNIASHMMLKGNVGMAIFYLSHAIELDKNDWTLYFKRGVLFSELGQFDSSIIDLRKALDDISAKKLDGTLEITPEREQNVWDHLGSVYNQMGIICFKKKKYEDAVYNFTGGIKCNPCITTLYKNRADCFYNLNEIKLALKDLNQVLSIEDEDQETKTKLATYNFILGEEFFSTGDYIKCIEKYNLAVKLNGSETKYFFERARCHHIMENIEECIADLKQVLKLHPNNVDAVGMLNRLIGGKPLDNILPFPPQKVLKKIEEKQENLITFPSISLLGVNRVKKSKEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWU5</accession>
    <name>A0AAD5XWU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Programmed cell death protein 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000176">
        <property type="protein sequence ID" value="KAJ3222423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWU5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052815">
        <property type="entry name" value="PDCD2-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46421">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46421:SF1">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Programmed cell death protein 2 C-terminal" evidence="1">
        <location>
            <begin position="373"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="558" mass="64184" checksum="335E508E5DABC0E8" modified="2024-05-29" version="1">MQIGYEANQQLKGAYSKKNYIMDKLGGNPKFFPTINISPMCFNCKEKCLLITQLNTTVDEELERIFYVFACNNRKCLKVSGSWKVLRVLRKVTKLKKKLLTNINEKDTNGKNPLTTDASLNALSTEKKKTKSASTKKFIINDLLTFIDADNFEIPLFGSTDALNTVQNNSFAFGDAPMFGNVHFGDVSPNELSNEINNLIEERDKIYDFNEEHEEFENDNDKSNNILISEITANLNELNLVSDETNAFHFSETLIDFYYEDRESDFENDNIFYSSSDDTEEEVQKKKKRKNNYNNVKYELKLLEEYEQRTGDSKFRLFMKNDTPTPSNTEHLTKTKKPLLNTRDLNENSSSNNSITWDGEVYENIVPNFLTTEFNKFLNAIKENPDQLIRYEFNGQPLLFSSLQEVSKKEDLKIKSIFHPKSGSTIFSEIKDNALISKCQNCGSNRTFEFQLMPKVLEFLKSDELNYMSKILNNGSSGDFKKNTISGPKKNSSNKYEFSEYLNIFGSGLDFGTVLIFSCENDCFNKNIDNNLCTILDENFKSSLSITEEICIVQFEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX04</accession>
    <name>A0AAD5XX04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">25S rRNA (uridine-N(3))-methyltransferase BMT5-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000152">
        <property type="protein sequence ID" value="KAJ3222930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX04"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="15149" checksum="742B15329BBF84FE" modified="2024-05-29" version="1">MSEDIKKVLILGDGNMSFALALCKLLWKENGNLLNAAHTYFGINDKATKFQIIATTFDSKEQLMTKYHDAKEIVSKIEKFGKEKIQILHGINAWELSKEFGSFDDKNSIGEGKCESMPLGKQLFDIVLWYVIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXA6</accession>
    <name>A0AAD5XXA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001206">
        <property type="protein sequence ID" value="KAJ3205412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXA6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="420" mass="44888" checksum="61E6BCDA0F834B0D" modified="2024-05-29" version="1" fragment="single">PGRNRYQTTTVTCTETETETETTCSSTPTQLTVFSTITTTSVTTSTTTSTHTLSVQTTSTTTDVCLGKREECLPGFFRLVECGPCIQPPTLTISEQQTTVTTTIAGPTITVTTSTTVPPTLSPIACDKRRCLPGYIRIADCAPCVAIPITSTSEPATIFSTVLTTISQVSTLTLTSVQEKIVTETLTTTAPAELVSVDNTIVVTVTKTQPPAITPVACNTVKCPPGLVRLAPCAPCVENQKSVETTTLTSSTIINPEPKTVTNFAFVQVAAASEVRKTLISTVYVEVTKTVSDTVTVTETAGNAATRIVREETTVSESMQTSEVLFHFEEVKETSDEEFALANDVKVEEESSEDGSSSSESTATVEYESTATVGYESTATVGYESTATEGYESTENYYDESECIIMIMIMNTTISNKIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY51</accession>
    <name>A0AAD5XY51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000328">
        <property type="protein sequence ID" value="KAJ3219735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY51"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase alpha subunit" evidence="1">
        <location>
            <begin position="313"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="783" mass="88670" checksum="C695C8E6BBD475C3" modified="2024-05-29" version="1">MSSNTSFSEIETNNLLYRNLHIDLMLDSNHTIRCSRYEDHHWKHCTLVNEFSEHSTLDIGIEQLSLFHTPASLNLISSSQLLSKDVKFTIYILDFLWEGLALDKCSHISIDYLYRALYPIATTIESIVILSDSYCSNPDDLVDEIQMPRQYLCTEDIPQFYINRFIYNNNSVSYAPRINRVRLAPINTDNLKYIMSSSEHSMLSSFCNLPDHKLCKGHIQGVTSDLIGLPKFLTVDEDNIIDLRGLLNKELFNEKVSIEDYSTGVRESIMGKTGIVRKGLLGMTPLTSCRGVATILWDVPKHHIYLPESWLKRMKIPYRDEDRVNNLISPSYKFRNAVRGDLGVVLRCPVISTSSIQPVEIYPWNNMSIGVSVEMCEPLNLDFDGDELHIALVASSESREEIKVAISMDKDLKFSKERINSILRSEILTTDEYSNILSSGNKDEQSIYDDFMMASTCSITELSDINYTSDLFVASRCKESSRKEVVDNYMSPKHQMSVVNSSLVAISHVAKSHLTVSNGYTFARSLKLISMESMVNPKTKDWESVWTPNRGLNNVASSGLKVQYSNEKFYGCPGARLATKVTNSLIQHSLDLAKHSERISDTSMVVAFLSNSNDHVRVIGKDNNLRVERYKVSPRDKDKANVSLSRKYQSKVYMCTNRASISKLHVSNCQKCDIVTYTLCYIVRALGISHSLDELADLANSIYVSLYIDSGKKPLTGTSPANFLTYTNCSFIVKYIADNIKVVDLQKIPMKQVESFSISQQSPLQSICLGNFTNLRYRSIAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY60</accession>
    <name>A0AAD5XY60_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdopterin synthase sulfur carrier subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000068">
        <property type="protein sequence ID" value="KAJ3225193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY60"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990133">
        <property type="term" value="C:molybdopterin adenylyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00754">
        <property type="entry name" value="Ubl_MoaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359:SF1">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9059" checksum="304D753B023E16EA" modified="2024-05-29" version="1">MVKVLYWAKAKELVGISDEEVYIGAPTPVSHFILKLENLHPILKTLNNTNLYALNMEFITNFNSILNNNDEFAIIPPVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY68</accession>
    <name>A0AAD5XY68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL18_2</name>
        <name evidence="6" type="ORF">HK099_006510</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000567">
        <property type="protein sequence ID" value="KAJ3215123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY68"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000039">
        <property type="entry name" value="Ribosomal_eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17135">
        <property type="entry name" value="Ribosomal_L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="299"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="145"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3215123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="351" mass="39212" checksum="C4B964F1BEB6A3FD" modified="2024-05-29" version="1">MGVDLPVKHHVKNSKRSEPKSEDVYLRLLVKVTRRTEANFNKVVLRRLFMSRINRPPIGLSRLARFLKGKEEKIAVIVGTITDDDRLLDVPKLTVCALRVTKTARARILKAGGEVLTFDQLALRAPLGKGCVLLRGPKNTRLAVKHFGKPGVPGSTTRPKVRSKGRKFEKARGRRASRVMQDRSSINRSSISSPYTQKGGQKAESPGSTNNAAASAAGNFSKHDIDSAFEILSKDGKKITQENVCLFYKDLFGNCFNKVPNFKNGNIGSWLKREELNRDNLNNLLIKKHLPANYYDETFQNGDLEAVLKEFDFDGDEKIGLNDFISIKNHYQPSKVHHLGSQKNCSPSTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYC8</accession>
    <name>A0AAD5XYC8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS20</name>
        <name evidence="5" type="ORF">HK099_007657</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000760">
        <property type="protein sequence ID" value="KAJ3212847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYC8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000002">
        <property type="entry name" value="40S ribosomal protein S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_uS10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005729">
        <property type="entry name" value="Ribosomal_uS10_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01046">
        <property type="entry name" value="uS10_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="4">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3212847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="122" mass="13921" checksum="E37C3C3851EAC90F" modified="2024-05-29" version="1">MSYVAPQKKFDDVAEPKIHRIRITLTSRNVKNLEKVCSDLINRAKEKDLKVKGPVRMPTKVLKITTRKTPCGEGSKTWDRYEMRVHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIQNAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYK4</accession>
    <name>A0AAD5XYK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_004510</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S9B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000003">
        <property type="entry name" value="Dipeptidyl peptidase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.140.10.30">
        <property type="entry name" value="Dipeptidylpeptidase IV, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050278">
        <property type="entry name" value="Serine_Prot_S9B/DPPIV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731:SF200">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 10, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731">
        <property type="entry name" value="PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Dipeptidylpeptidase IV N-terminal" evidence="15">
        <location>
            <begin position="236"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="14">
        <location>
            <begin position="775"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3226629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="976" mass="110616" checksum="D90BFE7123A34CF1" modified="2024-05-29" version="1">MSRSISPSRGRNASKNRARSPSVGVEDGKYERDFDRDYIYEKDSETKLLQPKLMKQPPLYNQKSNLGPQGLSGYSTLFKRKTFLLLKSPIFLLLLLGTVLLSIVSIAISSNKNLPTQNLNQNSLDNTIKNQKSTQNSKAEEELLTSNITHKIVEANKIIDGRPRLDFQIPSSLFAGASENLKWVNNDLDGSYVVKTYENAILLKHIEKETETRLVPPNAVIDDQGTSLHITDYSISFDLLYVLVATDYEKGWRHSFFANYYIFDVELKTNNALTTSKSDKSIPGALGNGKISLAIWAPKANHIAWIRDNDLYVTSILPGVGEPFTLKETRITNDGSKQVINGIADWVYEEEVLGSHDAMWFSPDGSRIAYLKFNETEVPEYHFQLYESPHGSYPREVSVKYPKPGFPNPVVTLHVATPSTTNDISDIAVQFKNEENFSDSNRLIVEVKWLTDSDTLLVRIMNRVQDVQRIFLVTPVLKNSKEIWEAVLIRDEPSVDGAWFNLLQPAVVVEPFADRSEPSYLELQEDANGFTHIAYYADVTRAEPTAWLTKGNWEVTEISAVDFQKGILYYLSTEVDSTQRHLYQVHLNGFDNKKLTPPSGLTYEKTISVLNMDSFKTSKTKRDKGAEFDLKEKIDISDSDATGIELELYKNKKKLKLVGEEGVYEALFSPKKKYYILMYHGPDVPWSRIIKTDDDWFKDSITNQHTRNAIPTYSIPQRNIFTIENEFKQTMNAKIIVPADFDPSGNIKYPVLMKVYGGPGSQTVNQVFGFGFMDSVANAGFVVLMVDGRGTGFKGRKFRTCVSKHLGKYEVDDQIAAAKWLSKLDFIDSERIALWGWSYGGYMASKVLEANSGFFALTMAVAPVTDWKYYDSIYTERYMKTPELNEKGYQNSAVTDMTGFENGEFLLIHGTSDDNVHFQNSADLIWRLTKAGARNYRVQFFTDSDHNIDAGGANKEVYALLKNFLFDKFNVMEKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ78</accession>
    <name>A0AAD5XZ78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002422</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ78"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="21364" checksum="0D813792078830F7" modified="2024-05-29" version="1">MNPFKQNTVYKFRRSYHAVGFAFDIDGVLIKGKRLLNQTKPALKLLSERKIPFIFLTNGGGVKEQMKADQLAQLFDLPKSLVKKYRNDLVVVIGGAKNECKKVAKNYGFEKVLTTNDVLRTNHSIWPFSNAFDSEEDDSFDLSKEPFKAIMMFHDSRDWGRDLQICTDILRSKNGILGTVKDNGTPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZK4</accession>
    <name>A0AAD5XZK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000319">
        <property type="protein sequence ID" value="KAJ3219968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="327" mass="36135" checksum="4B5CF0340EC785DE" modified="2024-05-29" version="1">MFETNLEVAEAELVRLSNFRAPKDKLTILNNTMQIVVDLIHKSSDNKAGNDQILPVLVLLLLRSKPPKMISHIRYVAPSISINTSRNDTPEISEVSPLQQNSPLSQKPQVQEYNPPSIQIGDLASQVFQSTSGFLGHLFKEVKNVGDKGTIMVDELLDSVLGPVPTETVSTTLPNATSTNLNYPGIASSSKKKEQAKMKKQGSLPNFQVFNNDRCEEEKDTGNKGLKQSPSFPSRNDKYKNGNSQEDYELELAIALSLSTVEQEKTQLEESLEAFLPENANFPINETEGINSVSNVETEIGTSISVISEKVFTDVLNKNVNNNKEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0R8</accession>
    <name>A0AAD5Y0R8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000181">
        <property type="protein sequence ID" value="KAJ3222312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0R8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="262" mass="31357" checksum="1232A0D5656DBF82" modified="2024-05-29" version="1">MKEKVYIKSIDNKKEAKEISEEEETLKQLADDTIKSETKGMFSFPVFKQINFLFKLFFTKKFISHRLGGLNYLIQWFLALGWWIYDYDSFKDSLLIWSLPLSGVFQSLNAMSVFWFLPKNTKETGYFSDKKTMSYSFIKENSFFALLLLFQFTYFNNYFFEIYKKTFIFELIFVFLPYFFRPLWPKTSFRDSKGKENKSEKNFGFYSYAIVVTKCVYVWGVNLGKHFFGFYLNYVRFLNRLNEDHKKSLYLSLIFGCAAVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0U6</accession>
    <name>A0AAD5Y0U6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">37S ribosomal protein S22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RSM22</name>
        <name evidence="9" type="ORF">HK099_003578</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000235">
        <property type="protein sequence ID" value="KAJ3221352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0U6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052571">
        <property type="entry name" value="Mt_RNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184:SF5">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="563"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="572"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3221352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="632" mass="74107" checksum="147D3CC40BF02362" modified="2024-05-29" version="1">MYNYKKQLKLLASHRIGQIVYPTYLTNKLLLIKKDLKKNLLKQDLERLLKNFWEKGKFNNINNFNKLKNLKKNSNSNYDKLHEEFNLQQVQENNIIQFGERESLVYALVRNPLTYSAAFKILMELKFRLPEVDQFKSILDFGCGSGSASIACLETLKSISLVQGVDKSLDQLKLFQQFFEFYANVDFHLKRYLPLTKQKKPFPKILNALATPDTLYTPDPNKFDLTISSFVFEEIVEENMRLQYLKQLKDLSANTLVFIEKGTPGGFKLILEIRNFFLSLNEKKKEDNWFVVSPCTNDLTCPMETTRKKQWCHFSQRVQRNSIMMNLKNCKSNQEDIKYSYVVLKRGQRPLRSPNIEYDQMNLKAEELEESEVEEEHSVREEQETLFHENIQRSTSANENRYDVTRRNEASLNRNDEVNSLQTHYEGLEKNLNRNFIQHHLTMESKNDISQNREEAFHGQEAQGSSNTIYNSYPKSSAIYRDHNAINEELICDSFHWKRLVAPPLKNHAHVVLDVCSESGQLERFSIGKKSKQGLNGGYHDARKSYWGDLWFRKIKKSVTRNEFDLPNDSNSVKEEKSEENNKSRHSKDKNVRSSKHYNENFELLNFQESLSLSKEQILKDVTFKNINSKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y252</accession>
    <name>A0AAD5Y252_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000076">
        <property type="protein sequence ID" value="KAJ3224924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051492">
        <property type="entry name" value="Dynamin-Rho_GEF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN FUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834:SF20">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="344"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1411" mass="162949" checksum="BA4EF8F3D9DD9210" modified="2024-05-29" version="1">MNSFPLNKFKKKRSPSSTKSLHQIGSSHNSSSSLSSIDVKCQKQEEEENLQTAINLRIVKLIEELGFVNSVTTPAPYHLQRSTSVLSVNKELASETLPSVNQPVLVENIFRNEFKIDVFNNKLAFIYTGFDDRIGYVIVALKEEEEFVLCYVMTKIKYKLINLEKCANKTVQATAKAKNHMIQLDWAEAAFGHFLRLIYKELIEDQEKYGFAFTPAVDLEFLKDDMEIDSMAKYFKENCQEIGSQFVNELALLECSPWRESVSSYVVDVITNSNLESVDSVETSNYNKLESLLGINFSSIFKIQTKTLALKENIEFSAEVNYQTRNLVPKSKEGFNFDVICSKIKELVTSERAYLEKITLLEEKYYRPLRDGAFINDNYNTATSKARCFPDMTKLMNLIKNFIAELLSEDIILFEGLEIPTLNRMCKVFIQQAEKIRMEYISHFEDLDTSETYLRDCPNEDFHTRIRNIENDCIKEFEADFPDLTAFTLSDLRIQAVQRLPRYLMLFSDISNYIPEDHECSMYFSEAVNTMKSVVSSVDQQNVLEKTKKLVTVLSKSFEDESYKNAAYPMSIKFLISELLIEGTCLIFFVEKKKKKFISEKKTFLLQLFNDRLVLLVKTKESIEKKDENSKKSRENFKSELELYGYIELKGAEVWVSRNFDDSNNVNGIVIGTNSKTNKEIEEVFKCDVKLQRSAQRRRTMSKIFFNFKGGPVFGKPEVDDDYLPKNSERLEFFFPEKNESDIKDNKIEEINDFFEKVKLASKYHEYVKDDKKQSLKLYEFKERQALTYSFRKDGILNKNKKSKFLLVFITATSVADAENEILMLKKLISPDNQRDSSYCFIGWICQHEGKFRLSIQSMLDKYQFHTIPQYWFDEAQFPAVCSHNILLCLKQIDTLIPLYLLPESQVKQECDVNSFCAKVFQPPKYPPVFKHFEHNEVDAKKSVDFVDNLSTKSKAPVLFSIKNFFTKVVNAKEKRIYEKKSSSPVVLNEEDACEKGKLKKRFSYRKAAPKICENQKGSLKREELLQKRTNSVKDPLSLNDDESKKKSSSKIVEADEIKIINAQCAIEAIFKNEEELNLLAYLFECIENKGPLIYQELSLFSDIHKSHAESILKEYRPKFNNENKFFQSIEKLSLLNKLVLLKVFITTLSTSGRILESTEVTKFAWIGVIDLRRLANFYLHPIFSDRVDFDMASEILSVMVETKLKTLPVALTSHKSETFLKIEDSFTEVTNITAPLIVKKGTLCVIEEEEENTCAIDNNPNSPLDNYSKVLNNNINLKMENDPTPKKNLLIEKCPEVDVSTSAECVSNKLDENLDCKDEIITSQVSSSSMETMVNYNEEVSQKKFLDKHFGFMGKKQLIKKRRSISFSFTQSIQQGNADAMARKDSYLKKSLSFCFEKEKGKEEKTMDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y296</accession>
    <name>A0AAD5Y296_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000069">
        <property type="protein sequence ID" value="KAJ3225164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y296"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="202" mass="23697" checksum="66420ADA1F0F473F" modified="2024-05-29" version="1">MAFLTNPGNPPIKYEEEVLNSDTFPDSESNIVVIEFKKTERTPSSGMTTIETFEKEKIEELVLRGKIRKEDAIFPYSSIDEKLEKEGYFNNSKEYVYYWPPQEYLNYKLEQNFGIKSERSFKQDINEKKFNLENRKKRNYNRNGNEGLDVLENTLEERNNELEHSLGNTGSPLVTNDVIGFEYDSEEDNEVLGLLKKRILQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2A3</accession>
    <name>A0AAD5Y2A3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000068">
        <property type="protein sequence ID" value="KAJ3225191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2A3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="5">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS N-terminal" evidence="6">
        <location>
            <begin position="496"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="10"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="314"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="633"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="726"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1063"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="320"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="654"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="664"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="676"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="728"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1065"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1084" mass="121806" checksum="14B35D77F01690E4" modified="2024-05-29" version="1">MSLPLKGSRFSSEQTQILEHHFTNVNKNPTKNEIIDLSNNTKLSESQVAGWFTRRRSKDKASNYDPQKVQQQYQQQQQLKQQTLMFQNSNNPNHQMPLPLSRTNSDELINLNNNNQGYLMQQAGQLTGQNNPSPHFFAQQHAPNSNPLPLPPNLTPQQHQHIQMQIQQAQLQLLQQQNNKNNSTIPITGAGALTSVAGLSLTDNLQMFNQQQLNALKFNSTMPLIPNNRNSPLNFMASPHIMNSGQFQPFSNNTNTTALNSTAVQNSQVIGDAQLQNGISTVGKVNPSPSVPQMIGTGSNLNLAGFDVGFNLQNHSASTNQNPNISNNLSSQNSSLNLLNNNLNSNQSTNNLNSQQQNQLQLQHQFQLQRQQQMQMLQQQQNFDQKSLQHQSPILNQQIQQQGQQQSYDASQQQNRQDSPEEVEEKLVLSSDGGLLNVKDSSKFSRIILSSYKEQLEQMEKLSGNVEIDKKKKIMKNFEFVREGFFDIILKTLDIGILKKFVDSKGFQCFKPFLVDAKKNKSNKLILVILRTLKHLPIGLEEIKTSNGLAKIVKQLSKSDFDKEIIDISNSLVNDWSQMVLNKNAEDDNNKKRARVEDVTNVPTAKKNSLSEGTYQAISYIYHKFKIDTQENINRKRLRDDSNVGPTPKKSNTENETTNLNKTVAGTNAINSSKVIRKDSAPSPKDSKPATMAVSFDPFKEDKALTMPKIKKIDKVIPKVIETKNMDSMDQQKSPINSQLQPLPDSPTNSTNNTLLIDSPSLPSYRRGQSPTIDSNDLKKKKKVTFPSDDKLVQVKIFYIDEAPDENENENVSVSAPINPEFDLGEGLQDFKKRRLRMVSSIPYVRPPLLDLQQNSKLRNPEVISQEKLVQEEREKKEMEVNYYEESDYPLSADESLIISQNVQNTDMEKNCSNLILMKVIPFLDSTIEENAKNLDILKKQPQHVIQPQKSLNSGFTDQNANNTGSLMQQQILSKLNLSAPALNNLLNVNPNTLPGYYNQQKSQQPSINNLYVGLQNLVSGVGSGTGINQNLNPEILKAFIALSAQQQVPQLQTVQPLQQLPVSHQHSQQLQPNANLSVGSPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2I0</accession>
    <name>A0AAD5Y2I0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ethylmalonyl-CoA decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Enoyl-CoA hydratase domain-containing protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Methylmalonyl-CoA decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ECHDC1</name>
        <name evidence="14" type="ORF">HK099_006589</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Acts preferentially on (S)-ethylmalonyl-CoA but also has some activity on the (R)-isomer. Also has methylmalonyl-CoA decarboxylase activity at lower level.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2R)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2</text>
            <dbReference type="Rhea" id="RHEA:59540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:85316"/>
            <dbReference type="EC" id="4.1.1.94"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:59541"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(2S)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2</text>
            <dbReference type="Rhea" id="RHEA:32131"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:60909"/>
            <dbReference type="EC" id="4.1.1.94"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:32132"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(S)-methylmalonyl-CoA + H(+) = propanoyl-CoA + CO2</text>
            <dbReference type="Rhea" id="RHEA:61340"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57327"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="EC" id="4.1.1.94"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:61341"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.94" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2I0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004492">
        <property type="term" value="F:methyl/ethyl malonyl-CoA decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF27">
        <property type="entry name" value="ETHYLMALONYL-COA DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00056546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="313" mass="34780" checksum="1685D63B2C49743D" modified="2024-05-29" version="1">MNQNNLKLLQKKFKLYGGLGSVDFNPNFQKSIALVSLNNVESKNALSPKMMAELSEIVDSLENTSHDKNYPLTALILTGNKKTFCSGFDLRMTSSDNKFKGKEFANEMTHLMNDTLRKFSKLSLISIAAIDGWAIGGGAELITACDFRCLSKNAKIKFVHSEMGVTTDYLTIGWGGSGRLISILNQKEALKILVSGKTLTANDCLQNGLADVVSEESSYGSLTDTVSINPVIKKSLDFLNDFIFVDKENSIMRSSSSIKSFKKIISSFSEEKPFIKFNEIERDAFVSLWGENDQLMALERKIKIKNAGENKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3Q9</accession>
    <name>A0AAD5Y3Q9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_002926</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3Q9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="523"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="8">
        <location>
            <begin position="164"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="10">
        <location>
            <begin position="244"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="9">
        <location>
            <begin position="348"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="583" mass="63323" checksum="E1A4399ECDEBCF29" modified="2024-05-29" version="1">MNPTSVDNKKEVPEAIAIDVTAPTDSKKEVLLESTQVVSGEKPFFKRPSQRSQIIHVVVMTLLTAYFIWMTIKGSSKNGYIPATLIYIFIALRTMAKYVNITRTFYNPLGKAYDATIAKVIGAIPEKIRLPLLALVWFVALIVVAVVSPVTEVGNVVQRLQSALGVFVFLGLLYVTSSDRKSIPFRTVVVGMVLNYIIALFVIKTQAGVVVFSNFSTLIKNFLNFSEYGLEFLFGKGLAHTYFVINVFPAIVFFCSFISVVYYFGGMQYIVQKMAWLMVRLMDTSGAESVVAVASPFVGQGESALLVKPFVEFMTMSELHSTMTSGFSTIAGSVLLAYQAYIGDLTPILTACVMSVPTSLLVSKMRLPEKENSLTRGEVKIPETEEKEANFLHAAGNGAAVGVNLILLIGGSLLSIMALYACADFIVGFLFQMVDGYDTFNPSPDGKPVWVTIQLILSFPFYVVAWLVGIPKDDCRKAGEFMSMKMVVNEFAAYAGLNAYAIGGVGFDGVYKGPTGKFEVRTIKLLAFALCGFANLSSIGIQIGCLGAMAPTRSRDLAKLAFSAMLTGTISTWLCAAVAGTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSZ6</accession>
    <name>A0AAD5TSZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPI-anchor transamidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002379</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001787">
        <property type="protein sequence ID" value="KAJ3201073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSZ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003923">
        <property type="term" value="F:GPI-anchor transamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1460:FF:000003">
        <property type="entry name" value="GPI-anchor transamidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028361">
        <property type="entry name" value="GPI_transamidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001096">
        <property type="entry name" value="Peptidase_C13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067:SF1">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01650">
        <property type="entry name" value="Peptidase_C13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500138">
        <property type="entry name" value="GPI8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019663">
        <property type="entry name" value="Legumain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00776">
        <property type="entry name" value="HEMOGLOBNASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042069928" description="GPI-anchor transamidase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR019663-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3201073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="43599" checksum="87E39C8F3F051373" modified="2024-05-29" version="1" fragment="single">MKYQLIILSLLYCITRTIANNDNKLTTEEEKLSKKLFSQVDQVEGFFSTSGHTNNWAVLVCTSRFWFNYRHIANTLSIYRTVKRLGIPDSNIILMLADDVSCNPRNHFAASVYNYAGSNIDLYGDNVEVDYRGYDVTVENFIRVLTDRMDPKTPRSKRLKTDDRSNILVYMTGHGGEEFLKFQDNEEIGSFDLADAFAQMWEKRRYHEIFFMIDTCQAASMYKRIRSPNILSAASSLTGEPSYSHHVDRDIGVAVVDRFTHRNLQTLEKLGREEQATLKDLFDTYDPRDIASTPGIRTDLFKRRIDQTLVTDFFGGVQNVELTLEAYKLDEDVKNFKLETDSNTKKTNNNISNASTPPSSDTFTQELKFVDFKFRNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT70</accession>
    <name>A0AAD5TT70_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sm protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_002806</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001964">
        <property type="protein sequence ID" value="KAJ3200133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT70"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01722">
        <property type="entry name" value="Sm_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034100">
        <property type="entry name" value="Sm_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="81"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3200133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="123" mass="13948" checksum="2C4A354E378BC2A3" modified="2024-05-29" version="1">MTGKPILVKLKWGMEYKGFLVSVDAYMNLQLANTEEIVDGVSNGILGEGEVLKGFKEYREKYMLKAKDREVRRKFVNINRGNQNNFSNAKFSEGNLDDGENSAATSSSIREDLSDATYLKRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTZ5</accession>
    <name>A0AAD5TTZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001569">
        <property type="protein sequence ID" value="KAJ3202451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTZ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055334">
        <property type="entry name" value="PEX8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214:SF1">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="466" mass="54380" checksum="C51EF20788E1AD63" modified="2024-05-29" version="1" fragment="single">AKIMQITFQTVFGLNGLKFIVTEESLVKEALARKTLSDNLVYSNLGRFSKFLSIMIKLVSNDDLERLILLFEGTEKFTRKFSTVFLYVTEDNKCEMEWEYLQKVLFVITFVSKGVTENAIFAKTKPLKVFSLIKITFRVFFNLHFVTLKFGSEGFSVWQQVLKNLVELMEIYHDDEENENFDTILTDLMKFAINYDHSSNENKIIKSSLLYTVALSKQLSNKLNLSTVAKLMNILNHYIPVPASREILNQNEEKPSDSSFNVEVEISREVNLFFQSVFNDFKFASLIFTDCPKYATLIIECYPTKLDFDILLSGISVAFKSISNLDAALDNLKDLSKDKYKSEYFVLQTFTIVEDIFKKMSSTSEQKLQMNYFKLLFSQIRAINFQYLGSYLEILQCLIIKNELPWSVENKDDRDRFLTTEILEDLLEILFDIISDPRGYDYTRKDMCLRWFLELKSTIKELESTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTZ7</accession>
    <name>A0AAD5TTZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">H(+)-transporting V0 sector ATPase subunit e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VMA9</name>
        <name evidence="10" type="ORF">HK099_001547</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001445">
        <property type="protein sequence ID" value="KAJ3203332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTZ7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3203332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="80" mass="8988" checksum="0D0A7F393B6DB254" modified="2024-05-29" version="1">MSTINIIFVTFALVAFLTVGLYLAAPKNQDQVVFRTAIVLTAICCWTMYAITYIAQLHPLIVPEHGWDPYVKDAPAHENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU04</accession>
    <name>A0AAD5TU04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001326">
        <property type="protein sequence ID" value="KAJ3204212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU04"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052256">
        <property type="entry name" value="E3_ubiquitin-ligase_CHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16079:SF4">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16079">
        <property type="entry name" value="UBIQUITIN LIGASE PROTEIN CHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="176" mass="20180" checksum="4895098AF028F381" modified="2024-05-29" version="1" fragment="single">MKRKSSTELTLDKEEDKNPQIIESNQQKKLNLDDSLTCPICRDILTTPVSVHCPSCRKNMKSASVNHTIASLIETYLDDNPEKKLSTEELEERKNLNKISTANPMVFKDTEYDSEFDDEDDDDDDIFPISSSITCRFCNYPSSDGFRCPSVNPEHVRCYTCNELHPLIQPQVQENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU51</accession>
    <name>A0AAD5TU51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001359</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010001378">
        <property type="protein sequence ID" value="KAJ3203804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU51"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001123">
        <property type="entry name" value="CK1/CK1/CK1-D protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="36"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3203804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="540" mass="62492" checksum="C2F63C31B6B16BF3" modified="2024-05-29" version="1" fragment="single">MTTTQPQVLELQQQKLEVQKHRAQRQPSPTIVGNCYKVGKKIGEGSFGVIYEGIHIHSQIPCAIKFEPRKSDAPQLKEEYKTYKILKGSVGIPNAHYFGQEGLHNILCLDLLGPSLEDMFDLCNKKFSVKTVCMCAIQMLTRIESIHERDLIYRDIKPDNFLIGKIPNKSEGSTDILANHSLEAPHMTSQIYLIDFGMAKHYRDPKTKVHIPYREKKSLSGTARYMSINTHLGREQSRRDDLEALGHVFMYFLRGTLPWQGLKAATNTEKYEKIGEKKKTTPIKELCEAFPEEFGIYLSYARKLKFEEEPDYNYLRGLFLNVLKKRDQTNDGVFDWMWILDRQIKGRERKRDHYAQKQQQQELQQKQQLQQNLHQKPPQLEKNYQLLEMQQNKQSELTNSNIEIGTFIPLSSNTTADNGIGLNSIGKTVTQEINSQNINFNNIKNHHQKDSNLMVKNSAKNEENFSNNDVKTDENNNSKFITTRINHTQDLLVQQPCNLSNEQKHQQQLSQNQCANETVNPKPTKRKNFFRCFPCGSKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU83</accession>
    <name>A0AAD5TU83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Axonemal dynein light chain domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AXDND1</name>
        <name evidence="2" type="ORF">HK099_001279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001344">
        <property type="protein sequence ID" value="KAJ3204071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU83"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052845">
        <property type="entry name" value="Axonemal_dynein_LC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019347">
        <property type="entry name" value="Axonemal_dynein_light_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23052">
        <property type="entry name" value="AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23052:SF1">
        <property type="entry name" value="AXONEMAL DYNEIN LIGHT CHAIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10211">
        <property type="entry name" value="Ax_dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="650" mass="75462" checksum="31B8B844CCF8D2A1" modified="2024-05-29" version="1">MSLKPTNRKEVAILKHTMVALLQELGAEDEQDYPTDMHAFLSVIQEEQKIYDTVFEEIIRQVTVNMVERGDILSEIRNRYSHLFIKIPKHVRHLHTELVAQRKLNKRLTEELVRAKDTVCELHKEVEVIRKHDIEVAKQAQDTQEKLVSILTQSDNTDEILEEYHKLYKMQRDRLEEAVTITESEKRMWIDAATKLVMRIGHESGINELLQLHRFEQARLRSSNHMIEIIRSSNDSELHLIEKKSQDSILKLMQISRAVVDEDQLNIETITKMEKDIRLILKSLDCETTYESEAEKRLLDRFNLYDVKALSEHLFKWVEHITLVAQRFTSDKDLSVQEDLINIRGMMETWVEAGLKLLQKNEKTTNGKDYKVLTEALNSCNAEIDLWLRKVEMRVSGEDGIASHVISLQNQLEDRYTTYSARDFDKPLPASERVQLKDAFTNWIEQTTLLISTLTNTTEREQQRVPMHLENWLNRILDQINTDTDVRNEENVKVHNSMTSWMVQLLVKGAEELPSDQWDQEFHQLNQELISFNLNLLRDSGDLEMISDDKSDLRKQMLGHSDKWLTIAKRLLINEKKLVQKVLDEKKKVKVIKFNAADDIILPEDTSNLTAIGGASLSRNSSAVLTPDPNLGNEATKTSLIEIKEGEEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUD6</accession>
    <name>A0AAD5TUD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA-processing protein 14 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002191">
        <property type="protein sequence ID" value="KAJ3199089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUD6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029188">
        <property type="entry name" value="Rrp14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007019">
        <property type="entry name" value="SURF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369:SF0">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15459">
        <property type="entry name" value="RRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 14 N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="214" mass="25015" checksum="2AC38701D27A4D70" modified="2024-05-29" version="1" fragment="single">ERLLEHQSHFDKLLKMIPTKYYLSTLEKSDNSKYQKNKKNKKEIKILAKNAKFTKLDPEGQKSILDIQKSTLLEKKNEKEEIKEDENNIIVNNTNQEKKIIKPMSNISSTEARLKLQSRIAELRKNRRATQLPNSPLEKEGENLKTARSRAEILERRQKKLDERKNKKKLKSNSNKGGNVIDVNANLVENTKTPKKRKVEDTVLDEKQIKDDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUX1</accession>
    <name>A0AAD5TUX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001842">
        <property type="protein sequence ID" value="KAJ3200755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUX1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="79" mass="8705" checksum="10B0F7BEACE3494B" modified="2024-05-29" version="1" fragment="single">RKKAEIYRELLATLIENVHVNTIGGINNSGLQLLLPSENGTFEIAVEVNNYDLVKPIAGLLVYDGFQCKLCCDISKIPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV77</accession>
    <name>A0AAD5TV77_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000960">
        <property type="protein sequence ID" value="KAJ3209093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV77"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="94" mass="10957" checksum="0C8931B713E3FA9D" modified="2024-05-29" version="1" fragment="single">MGSSDNSNRPFVGNSTVTPVNNLNDSVEINMVTTINQEKQRFYFVDWLKFVLTVDVVFHHAIYVYFSGWWPLQKTWDVDGPTTTFFVTVLKYNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVX8</accession>
    <name>A0AAD5TVX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000903">
        <property type="protein sequence ID" value="KAJ3210184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVX8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041908203" evidence="2">
        <location>
            <begin position="19"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3210184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="270" mass="29174" checksum="D84068A3AD62C533" modified="2024-05-29" version="1">MKTCIITLIALTVGTTAASYGNSYAQQSEPQSAATNPQQQSVENYPSSEPEEKVEPNEASKKLPCSDSKQKQEPELEQIEKSKPKEKTKPQNAEEKSKKPQDAEEKSKKPQDAEEKSENEPSKAGKTKEVSKTKPQEVEEKSQKKKEDSEPSEGDNENPIQGNIIKPNSQELNQKLYATETPCEEEKNNAALTQTAKPNETATPSSNALPLEGSKGLYEAKKPPAEKPASTLTPKLPNAEAQNLGVGNAGNSLQAYNLFAAAGAIVLLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW18</accession>
    <name>A0AAD5TW18_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008427</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000920">
        <property type="protein sequence ID" value="KAJ3209850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW18"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="5">
        <location>
            <begin position="29"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="4">
        <location>
            <begin position="548"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="602"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3209850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="634" mass="71804" checksum="2B0A0F6C03E78BA1" modified="2024-05-29" version="1" fragment="single">VYKKKMDKVDKLCNIDQIDILRSLGLDRYISLPQLLVCGDQSAGKSTLLEKLTGIEFPSSSGMCTTFITEIIMSDGDVESYVVEYPTVQIEKQNYANLSADVQKQVELVEALIGKQEPLNSISDVKSRIEAFKSLTGGRIVSEGVLRVYIKKPKSARLTILDTPGYIHSTINGQSKDLPTKISAMIEEYISKSKTINIAVLPANRDLATNVVMSKVEQYDPKGARTIGVISKIDICSEEEFEDCVKLLHGELKPLELGYHAVSGNDIIPMKWTKATAKENLGIDCLREKLADILASHIARELPKIRYDIDIDLASSKNDLLKLGPDLDSNAEKLRQLIITSKKAKGIWIQCLEGGFVNNPKNLRAQLHKIQQSLQNTIKEMVDTEKFDQTKMKEFLEERRGPGPAGFIDYNTFSLLVYENVKSWEEQIQISVLNWSNTYEDCLKELLKNEICPLFFEMAAYTCKNVISLIKEEMREMVHELIKDESRPHTLDDHFNTAEDNLRRISESAFNVMALGIPKTATHFSGYAIHERLNSSTTPVVSNEVRAVTAMICKCTAYEKTAFKRIIDAVCQNIMERMLVRKGVDRIFDEIEKMDVSLFRESIKAKNKRNNLKKKIEVFENSIIKINEMYSRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW35</accession>
    <name>A0AAD5TW35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000778">
        <property type="protein sequence ID" value="KAJ3212448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW35"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="338" mass="38221" checksum="71FEC5F8586335F2" modified="2024-05-29" version="1" fragment="single">MTVFNNSLNCAENEVSDRKPVSTLQQQNSIPYNNPIVPVAEFFTNATRKAPKVSHDGQYIAFLAQGQNKNKNLQVEIQPLALYLQGLNEGRKVVVTHPTHDIRGYTWSLSSSKYIIYYQDKNGDENLKLYRTNIHTLETICLTPFEDVNLGELHSSYIYQSKSKPNQCVVSLNKIDKSIFDLYKLDLETAEIELHMKNPGNAIQFLCNDNLDVLVYAEMAKDGSIHVYCRGTAEDNWRNILTVDANETLQVEALTDDGKSLLYQCSKDEACTVLKKYKIESGAVEVLSRGNVDIADIKLNPQTNTPEAVCYDTGRRNWVILDEKVKDDLNTLVSLDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW62</accession>
    <name>A0AAD5TW62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000765">
        <property type="protein sequence ID" value="KAJ3212713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW62"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3212713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="538" mass="61116" checksum="7633C4B77635CEDB" modified="2024-05-29" version="1">MQQIQANAEEASSCSLHFPSHEITCLHCQNQQNQRNFADHNFTGSLAIVSTNNHNNNFNTTGFSSLIRPLDQSSLQKLQNPLDFYISNTIPFVNLNIQFSFTQQQYATTNFNYQPLHSQGFNTPSPLQPINQYSPTNFSSPSPQPSQTSNNNVISSSLSKGNSQNNLSFGLSSPTLTSSPRTNKLISKRSTKEKNVQFNKLYCNSCKIVQLGKFSVKTPVNETTCEIYCKDCSTKPPSYCKELMCSICKNSVGIGYIQKGAIFELICFSCDKKYMFCTECGGGGKFRIGKYRPIELFTPGLKKTCTLSHLRIGSIKISWQLCKLGKNSDEYKLYAHDIVNILNDGIYSLLAGAKSLEHPRSKYKSFSDLEVWINQIRAFIDNYVKLEMEECNIKRFISLARNGTHERAENIGFGIFEINTNFGTLCLRPFTFNMMAYTVSGVLRDMICDAVRWSQDYANQHSFDPIQYVWFALDDNEIIKKLFTKIKFKPIDEFLLSNPEVDRDIFTFVDNPYLCRGKKTDFTTYVCKASEFTSATFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX30</accession>
    <name>A0AAD5TX30_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001163">
        <property type="protein sequence ID" value="KAJ3205958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX30"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="308" mass="35701" checksum="10F31AAC0581BEAD" modified="2024-05-29" version="1" fragment="single">QCLECLDSLEVIEYQDKLKSSKKNFKEKKLQFDDLFGKSEVLLIDEEGGVSRCGNCHWEVVDRVCVNCETVFDLQHNFNHNHEALDEDSDAYDSQDNLIPIGNRGEIGFVRRRFSHNRYEVEEEDDDSFVTDGEEIVEDNSNHDFSSDFSDVTDTYSVNEREVDELNDRECVQEFMDLSAEEDTESQYGSDEKEDFQEQNVEEEGFNNEASLERILGNPEPSDDDYEEKEEILIKKSSSPKKKYVINDSDSDSETRCNAIATKNLRRKRRIELNNSDLDCSSEIPSSNIFGKNKKKKRVKRINSEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX68</accession>
    <name>A0AAD5TX68_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000707">
        <property type="protein sequence ID" value="KAJ3213463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX68"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="29"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="283" mass="31336" checksum="9C40D03DA1F499BA" modified="2024-05-29" version="1" fragment="single">MPTVLIGESRLSTPFTMNYQLFGSGNTKLLFVMGLTVSLEAWENQFNYFGKLKDYTAIKQLVCVFDNRGSGLSDAPAGRYTTCEMAKDTSELLDHLHWTSDVHIVGVSMGGMISQELALLRPHTFSSITLTSTHAGRTLAPLKGAFGIPMSLIYPQGALDTLASVLFPDEYLASPAPLEFVPVCISKKNSYTMKDVFWDTAMKRSKKTRASPLRGFLGQLSAVFTHHISLDRLEKLKNSQINFLVCTGTEDNLIKPVNSIYLAKMLDCKLQVFEKVGHTLPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXJ8</accession>
    <name>A0AAD5TXJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000598">
        <property type="protein sequence ID" value="KAJ3214709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXJ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1119" mass="128669" checksum="9EA30691AEBBDF03" modified="2024-05-29" version="1">MEIHFLINQDSKINEEQENQKLSIRKSTKKNSRKIPTNTKEVETDKDYKQKIDSFLEEGWVQYLPPSQNFSAAIELWKEARILAKIVGCVFREAQAWNNLATVWKSTQQIDLAINACENAWELSGMMLTVGLTKDDILTTNEKNESKSSVLEPKEDSTNNLGIINKAYNNFILKKKGQAQKEWKEVENLPDIPNVPLKAGKILGTVKKSNDNVMLDTLLSTGVVPKNFTKRRYSTDVNFSSEVLPKKESTKLKHGFSDNLLHQDIKDEKLKQTKDNQTKILQALSFLGLNEKGSTSKVAPIMKEAVSGRANSKAMKILGVDSMVTAGLPSQNIENSIKIKNEINPSSEADIPKSSRKFSFSEGQQPSDFSSEGDAKCFHRRSKSLNSSQSKEKVQLEKTEEKKTITSKLPIKSVKTAGSCSKESSNSYFKNSESEINFKINSFYEGDELNFFPTTFSAENFTTPSIGSFKDYNGQNFLSFVNTESFNESEMMKDRGLKKLNTCVKKMGSSFMENNRFSRSRSKSENSQGVYFNSSMSFEEFRDSTSNAVELLNSFGSVKKKNNFNCENDSGSAIFDTDARVYNDRKFSYKSLSGEVENGTEAKRKINKSYLNREIENFETSLETEVVEEKKKKWEEGNEFFNNDNFINPTSPINLKLFSRTVIFDKLDMEGVENRNCYFYNNQVYCKKINVEKEIQQDKISQVTIGEYFRDYKEGKKDKSNKRMTKDIVKNNPKIYSEWFKTRKNIPGYKKISPPLALFFIQLANTYGNWLCQDSFKNYLSALKLHQLAKLGLLEFQNLIFKRKIESKYYKPNTLIAEINGNLGISLLNYGLLKKSKDLMDLSLMGHSVADNPREIIRAQANVMAQGLYETIRNNFFLNFNQLEDEKRKREGLKFLQYFDYLAKISALQGDLECENMSRFNVGTALLLLNESEAAAKVYINLLGLDLTLLEKEFMESVYVPEKFDVLRELKRRVEINPFFKNKMDLLTFNFCEILIRFLSQGIKSVMLIVVSNLVNSSSELEEIKKKILVFEEMENREMLIIKKEFLIDLLNFIVEKFFELKVIKNEVVKRILEIGTRDGKSEEMKEIFGFDVLEDEEILKYSVYSRIKNVIKDLEKEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXQ6</accession>
    <name>A0AAD5TXQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prolyl endopeptidase</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006693</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000597">
        <property type="protein sequence ID" value="KAJ3214715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXQ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051543">
        <property type="entry name" value="Serine_Peptidase_S9A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757:SF19">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757">
        <property type="entry name" value="PROTEASE FAMILY S9A OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="8">
        <location>
            <begin position="115"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="7">
        <location>
            <begin position="595"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3214715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="768" mass="88570" checksum="49163D2E86479DB9" modified="2024-05-29" version="1" fragment="single">MQQNNLLKNYIEPTLNCPTSPTIQNKKEHPSLYYSNLTSNAIGRSYSVPSQQANSVQHSPAHSVNKANYFNDSRTLPSLEEMEQLNDFIIKQPSPTILTYLEQQCALDAKLSLGHGEEWSDGYAWLNDRENQEVLDYIEAENKYADQMLMSTRPLQRTLYKEFVSRLDESEESPRATFSDKWTYYTKRIPGEEYRVHCRIREGEEEAIFLDENKLANDDMFKDANYFKLGFLKHDPSFKFIAYSVDSVGNERYTVMFMDIDTKEVFLDRIEGVYEDFEFSNDSQYVYYTLLDEQERAYQLKRHKIGSKVEDDEILYHEQDEMYYLSLTKSCNGQYIILNSAAQITSETRIILANNSKDVPHLLFPRRDNIQYTVESHLDHFYILTNENSKNNWLCRIPVASCLDSSLTNWETLLDLCETVIEHRDFVLIEGFQLRKHHLIILERSNCLQNCRIVDLSIPGFNSYHYISFSESVYSLWPGAVDEEIADLTKATQFDTNTFRFTYTSFLQPKQVMDYDMNSRVMTVVHEEKVNGIFEYDPSAYNSKRLFATGVDGTAIPVSIVYRRDLLGCNMNPPEPNPLLLHAYGAYGSFVTPIFSSNRLSLLDRGFIFAVAHVRGGADMGNAWYEEGKLAKKPNTFLDFISVAEFLCKEGYTNPSKLAIYGRSAGGLLIGACINMRPDLFKAALTEVPFVDVINTMFDSTIPWTAFEYEEWGNPNDIEIYEVMKTYCPYTNVRGDLLAKELYPDLLVIGGMNDPRVAFFEPLKFVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXR8</accession>
    <name>A0AAD5TXR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Superoxide dismutase</fullName>
            <ecNumber evidence="2 7">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SOD2</name>
        <name evidence="10" type="ORF">HK099_006297</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 7"/>
    <dbReference type="EMBL" id="JADGJW010000533">
        <property type="protein sequence ID" value="KAJ3215594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXR8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.990:FF:000001">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050265">
        <property type="entry name" value="Fe/Mn_Superoxide_Dismutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404">
        <property type="entry name" value="SUPEROXIDE DISMUTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11404:SF6">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="8">
        <location>
            <begin position="7"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="9">
        <location>
            <begin position="79"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="110" mass="12169" checksum="5025CAD8E270A2D1" modified="2024-05-29" version="1">MLIFAVADIMKIHHSKHHATYVNMLNQFEEKQHDFLDKNDLTGQLSIQQNLKFNGGGHINHSIFWTNLAPAKKDGGGEPSGAIAEQINKQFGSFNDFKTKFNTAAAGVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXU6</accession>
    <name>A0AAD5TXU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000951">
        <property type="protein sequence ID" value="KAJ3209237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXU6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042274686" evidence="1">
        <location>
            <begin position="17"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="547" mass="60206" checksum="6E1DE83FCDACE701" modified="2024-05-29" version="1">MKLQFIQALLSTITLAAISDEPADEFSTKLQRQPSFALRSQPSQPRSLLTVEHVEEDYLGEITFETNENVNAVWLDNLNGLLNVDCSTTGEMKLTFDSPTNAKLPEVWGTFPITALISAKYSNCLGQEVLCEEDNICEVKEALGVQVIEGINLAAATNENDLVLSTTKQEFFDDTVTETSFNFASTNVESDDPSLNSLQKRFNKQKEFQFSKSWIDKDVFSTAYLDLQSIFGPSKISPESKITCRNCTIDYRLGWKISGHIRSRRCKTNSQRKCHTNKMSYELTGGGKATFDLKFALSGTHTVDIITIPIIPSIPLGPSAGITIPGIFNAGFFFEMGANIAIDIVGKIEFTAGIDITQNDFTFTRNSRNIFGSEADQIDNLNGGKVDFNLHKPTFKAAAKFIPKLSINPTFSAKIELPAVKNLGVSIKLGMGNELQFPMVVDTSEILEKDCLVSFALTYHPSIFVSAKALKLFQAFKELTNFPTFELVKKRCIKFKDGKILAQLDGNNTVKTAIASTASPQQTFVTAIPLPSSVIVPLIPTTATPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXV2</accession>
    <name>A0AAD5TXV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/arginine-rich splicing factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SRSF1</name>
        <name evidence="4" type="ORF">HK099_008043</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000842">
        <property type="protein sequence ID" value="KAJ3211312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXV2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241:SF304">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241">
        <property type="entry name" value="TRANSFORMER-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="540"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="655"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="775"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="322"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3211312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1078" mass="122780" checksum="68080899804C0B7D" modified="2024-05-29" version="1">MNAKRTSWQPSQPSSNAINNNWNSVTSPQSPSSNQDWNTFKTELINNNPSIRNNWGTSNLEPASSDWNGVPLRQSAIDNSNRKLSSNHNSGNVSPARKLHSSASSSWLSQNDPVDSWRKTPSPLHQHQPELRRHSSQQFQTNDSWRQLPSTLQQNQSSNSFQQRQQGNAAAKWRANSSSPSTMEQSSFHQSKSFSNAANNQQQDSWNNSDNTTPEPREEPWNRIDIATWNPEQSTGWGKAAPVLSESPTSTVSELPEWRNSYDVRSSSGDVNNSWGDGNTTNYTQPSPLSTPPQMLASKSWNTSSSTFESSNQRRSNSSVSWNKPASNVNSWNSPPVGNTFVPPSNGNRQLGQTRRSWSKHNSVESSNWEAKPSWETKPPTSPYANNTDVPAPKIAAGWGNPIVHTNLNKRMSHQQLRSNSWNSNSSVSFAEKAKGTWEPQVVKVDNDDEFNSYNNSSYSNQLQNRIVNNSLKKTKSTASFFDSSKTIASGRVPRESGFPARQLEQLNKTITSNNNNEEFSSYNLRKKLSNDMNSIVPSPRIYVYGFPDWVRVRELIDIFCDYGSVLNGNKNFFFDSFIVVLVGIMSNEIPPFAFVDFEGSESTMNAVSSLRHQYFFDMDRPLEILHEKKPVNGRGINNISNGKQEVTDVLLESTTIHVGNIPQNVQRSEVEKLFGKYGDLKRVQIVTRQKENRAFAFICYKNHNSAQNAMNSLRNSKSLHFNMSEPLKMEYSKIEKKKLTEKSSMLSLKKNTSKDELKLAEYKKDKPFQVNTKNSVYINLIPNNVGDEEFLEIFKQFGNIKYYFFVNRSTPEAYHLVDDTEENSITESDRLYERYGIVIFNNEQDAFHAVNSNNFNCCFPYLKKLTLSNLIFNTKNLALECLKIKNLFNEALNDEDENMKVLNLDFKLKRCDLEFNNAENCFKILNLILEFPENFTPDLKVEYSSIVKRTDSNFSVSANDSINNEKEEEVYRFEEEVIVEEVISERILTETFKEEVVEIIEVLVEENEQTEDNGIIPIEEIKFEDLMSGNDLDVTTEEITLNDLSLDNIPVEEINLKDFVNEEDDINAANVEVINIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXW6</accession>
    <name>A0AAD5TXW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001656">
        <property type="protein sequence ID" value="KAJ3201880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXW6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000823">
        <property type="entry name" value="Small GTPase RAB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="194"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3201880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="229" mass="24986" checksum="4FBC0084B3EC2020" modified="2024-05-29" version="1">MSTNSGNISEASNQQQQQANQLKPIQVKLVLLGEAAVGKSSLVLRFVNNEFIDNKEPTIGAAFLTQKCKLLDKIIKFEIWDTAGQERFHSLAPMYYRNAQAAVVAYDITKAASLDKAKSWVKELQRQANPNIIIALVGNKLDLEDQRQVPKEEAQLFANEAGLLFTEASAKSGEFVMEVFTEIAKKIPLDSLSSARSRNGLSTSGSNTNADGTVNLGDDSTNNSSQCQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY05</accession>
    <name>A0AAD5TY05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000544">
        <property type="protein sequence ID" value="KAJ3215418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY05"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039725">
        <property type="entry name" value="CC2D1A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13076">
        <property type="entry name" value="COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13076:SF9">
        <property type="entry name" value="COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="428"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="915" mass="103163" checksum="E994AED53EA9FF90" modified="2024-05-29" version="1">MSSKKNLPKQEDINDINFQLHDVEIDPDLEVDFNFEDPALLAELNILIKNQPKDVHTNSGSDNFETDVDLMDELQVLQCDMQFNSVKVEKIASSKNSIHEPAAHSIGETITSTVEFENNLSGSKVMHQTTTFQNKKLKYHENAETNSNSVDLTSILSSANIPSDFNADNVEVEVTDEDMNDPLMLAQLDDIAFSQFKSESKSSELSNQNNKLDKENDGLIPVKLHTAVDLDKNFLLQRQQEYKAMALQLSKNKEKVLAREMLSVKKSLDKILEILNYGGTLPSNFKLPPSPQEYLDKKSANSVSVPPLKTINSFEPESNFCKTSTPSKITKKPLVTSTVPPTGNLSSKPEDGKEGLEMDSSANVYEYLISKLRNQLKILSGLSDYHLKSNAKALAHVLLNMRKNLKSDIERLEVLSKSPTNNQPPFFQTKSFEYEVTENFLHLASDDLEVNILSGSDFNTSCPGVEYYCTFNLGWPVDDKYSDSKFETNRVYKCTNPEFNSTKILKIQRNSKAFQRHLERKKVATIDIFCAKQQSFSSRLFGSTPTLIGKCFLPLDQLLTKAEISEQLTVMDPSNVRKRLSAKLDIKLRLRQPIVKPSIIVKNVVWVMVNFYENLFDTNPVYIAINENSTNLTNFNSVPNKKITPPATPSKKITPPATPSKILPSKDTVVSKVEKKNITPNSKSLSINQTNAEPVRVIDNASEEDDIETLEFNFNNPDTMRSNYVIESEYNETLAEIKKFETNGKPIPEELTTKKIGLEIRMQLLITSVQTGALSMEGHLANCKNDVLELKKLTLRFMHHGRKDLAKLALKRSKIVEKEKESKTPSLANPPPTPKKVVKKWMIKLSSKDLIDTPELFAAIPSEDFTRRRLRSAYYGKVRVANKPSLLAATEVPFHNNNLQDSRALKEKSTICLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY70</accession>
    <name>A0AAD5TY70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000520">
        <property type="protein sequence ID" value="KAJ3215788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY70"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031367">
        <property type="entry name" value="CCDC24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28601">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28601:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15669">
        <property type="entry name" value="CCDC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="432" mass="50465" checksum="D9FB45AF254586B4" modified="2024-05-29" version="1">MIKPIIVQNNNNIQEKPDEVPISIWETLTETIPPEQLLHLASIIGPNLITEVQDVRTEYETLLEIRSDYRRDTEQNQHSVVFNEVDKSIVDWIFVDEFLQVNRPQSRADSLTSEKSLNSEFGNVMEKWKTNLSSQEWRKITQVLRKALKEEKGFLLKKIDAIYNLLDKERELRNKTENMDLQEIPSVKTLNEFSIKLEETVEKVERTKELNKIVEKTENKRNFKDSVCKEHLYQKSPQLSNELNPKKIIIQKEENLNEMFEEFLKLEEKTNFKIKLPTAKEKNASSLAEAKRNFKQKAPLKKGIDLKSEVMHKNKTSNSSTRAEIVSIKELQKKNKNVYGQADSKFHNLSSCLPQPPNSKLFSTHVVQSNSQKFRMRRIVKKEIDLTLEDMCLFENEEEKVHFPTNSHSSTVTVLSPLKLPFPPKKSERIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY94</accession>
    <name>A0AAD5TY94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000548">
        <property type="protein sequence ID" value="KAJ3215383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY94"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01167">
        <property type="entry name" value="LPXTG_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="197"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="256" mass="28408" checksum="C00948280EBC5725" modified="2024-05-29" version="1">MSFLSGTYSSTPAICQTPPMFSCFDFCTNNIKLEFNENIAILTPLKNSGTSCDISEFCEVQTFVFNKNDNNYFRRYNNVAAHGSNQTIQYQDGLLRSINRYPDTTGWVGGSCYSTLTAISLSEPPPKPSSSPLENTRDTGTNINIYIGLAIGLFLLLLFGLGSFYFFYRKRKNSESVLKEEQSNGNSSKVEGINLYPLLTNYVAIASYQPVLDDELEVLTGDHITIHSVHSDGWCTGVNERTGHTGQVAMNLLQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYJ1</accession>
    <name>A0AAD5TYJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Cu(+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cu(2+)-ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">RAN1_2</name>
        <name evidence="16" type="ORF">HK099_006634</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.8" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000587">
        <property type="protein sequence ID" value="KAJ3214851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYJ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140581">
        <property type="term" value="F:P-type monovalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46594:SF4">
        <property type="entry name" value="P-TYPE CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0186">Copper</keyword>
    <keyword evidence="16" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="16" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="631"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="15">
        <location>
            <begin position="99"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="15">
        <location>
            <begin position="189"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="15">
        <location>
            <begin position="274"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="13">
        <location>
            <begin position="787"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="13">
        <location>
            <begin position="869"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00080126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3214851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="950" mass="103896" checksum="547BA19B3FE40918" modified="2024-05-29" version="1">MSCCSETIKVTESTPLLSDAPFNCIGQCIKVLNVNSTTFSTIRSGVNELVYLEIVLKKESDLSVVSNQCLKKLRKHFESEDINLIDDDALKHSDEYDVFTTTLHLTGMYCIKCTTAVEKLLLNDTRVKFVETFLKPTQKVVFKHESSLDLRDIKSKIEGLGFVVVGQPETNNEKLYEVKSEANAQPNKQKTIIHLNGMSCASCVNSLESIFKSTRAFDLPDTSVSVSLFPQKVVAEYYSNSIDEKTLIKKCVDAGFDVILSHTESLLAEDSSKKKVEFLVFGMTCSSCVATLENILRVDGVEDVSVNLLTKKAEIAYDTSKIGPRELLDIILDAGFEAELYKSNDSNFLKEMEEEVFRGVTRETFISLLLATPCQFILGWRFFKGAYVALFKLKSANMDVLVVLGTSSAYFYSIYTITKNVYNDSTKDGKIFFETSVFLIFFILFGRYLEALAKGKTLETITKLLTLKPDRATLINLDAEFNEVNQSEIHVDLVELGDFLKIFPGSRFPTDGIVVKGESICDESILSGESFPVSKKVGDTCFAGTVNQSGVLLIKASKVGSETALARIVKLVEDAQTSKAPIQSLVDKISRIFVPFVVTCSILTFVTWNIICNTYPEVVPSTVTQFEFCLSFAISVLVIACPCALGLAIPTAENVLAFNKLNTIKRLVGLMENQPEDVLVNVVGALGACAKSVEGRSSIRESNGITPLVNLLTGTNQALLVNVTVAVGESALDTDSMAIIDRLDGVRLLWSLLKSPNPHVQASAAWAISPCIEHAKDAGEMVRSFVGGLELIVSLLKSENVEVLASVCAAIANIARDEENLAVITDHGVVPMLAKLSNTRNDKLRKHLSEAIARCCHWGNNRVAFGTASAVAPLVKYLRSPDEEVHRSTARALHQLSMDPDNCITMHEHGVVQLLLGMVGSTDTALQEAAAGTIGNIRRLALASEKAAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZC9</accession>
    <name>A0AAD5TZC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable glycerol kinase</fullName>
            <ecNumber evidence="3">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_007950</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>glycerol + ATP = sn-glycerol 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000820">
        <property type="protein sequence ID" value="KAJ3211670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZC9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07792">
        <property type="entry name" value="ASKHA_NBD_FGGY_GK1-3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000177">
        <property type="entry name" value="Glycerol kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000108">
        <property type="entry name" value="Glycerol kinase, glycosomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042018">
        <property type="entry name" value="GK1-3_metazoan-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000756">
        <property type="entry name" value="PRK00047.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF69">
        <property type="entry name" value="GLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="13">
        <location>
            <begin position="32"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="14">
        <location>
            <begin position="294"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00052101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3211670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="534" mass="58236" checksum="056C92D14D16E807" modified="2024-05-29" version="1">MGFFNCTCADEEVSTRTPNMKPVKTFVAPFVGSIDQGTTSSRFIIFDKHGQVVALHQIEIQQITPKEGWTEHNPEEIYETTLTSIKGATDKFVALGYKISDIKSVGITNQRETTVVWGKSTGKSLHNAVVWLDTRTKSTVEKLVSKTKSKKTNEFVSIVGLPLSTYFSGVKLNWLLEHVPAVSEAKSNNNLLFGTIDSWLIYKLTGGLNGGKHLTDVTNASRTMLLNLETLQWDKKMLEFFDIPQNCLPEVRSSSEHYGNICEGILKGIPIAGVLGDQQAALVGQRCLKPGQVKNTYGTGCFTLFNTGNKTILSKNGLLTTVAYKLGPNAEPTYALEGSVATAGAGVKWLRDNLNMINDAKQINEFASKVPDTAGCHFVPAFSGLFAPYWKDDAKGCISGLTSFHTKHHICRALLEAICFQSKELVDAMNADAGQPLRSLKVDGGLTNSDLCMQIQADILGITVERPAMRESTALGAALAAGLSTGVWTSLDENVEGGFKLSDGHDYFESQILESDREVKFAAWKKAVEKSFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZI6</accession>
    <name>A0AAD5TZI6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000788">
        <property type="protein sequence ID" value="KAJ3212243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZI6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="395" mass="46449" checksum="FFE51C2CB4C5451D" modified="2024-05-29" version="1">MEKTKTEYLRPSPNEEKEVKLKQFQQARLTRLLQVRKQQAQIQNKKIAKYQNLLSASWNQTVKDLEDIWVVNKLERLEKLKDVAEQNESLIGLSHSEAYQIEIIEKPKIQNEKNLKKRKETEFEKKRIKTSAKILREEKYLERRKGESRNENRERIKNLELERSIKVVQNLKKNKKHYLDTVAIDNLNLQSVNLNRLTKNKLALKYKYNRDSNIESLDFDANCLHRGFPGVAVKIVKTETEKNCDLVKRNIASKNAIIQSHLNSVKLKNEELKKIENSKSAFWRYKNAVGVIEKEKSKKEMLKELDQLNKDDLKRKQENSTINSLFYRRNETLDDVEKIFRNRFIVQDVPVNLKTPKLTKSNSKGGGYTFVHDNSAENYRFGTESSDGSIKIIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZN9</accession>
    <name>A0AAD5TZN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006696</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000598">
        <property type="protein sequence ID" value="KAJ3214710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZN9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000688">
        <property type="entry name" value="zinc finger protein 197 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3214710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="244" mass="27981" checksum="5EF34A958A672AE3" modified="2024-05-29" version="1" fragment="single">MNISCLINHQNLHQQHKTKSVGQVVEPLLNSLLDYFPDKLSQQRFGKTNPAAFKLNNDQNTISSPNLRQQRLSFQKLHINTKLNFPEASYKTPLSANSPTTNSILDSSTSSISPLENSFSLKKLVAPPSPVSSISNHEDSANDLTNDDEYPFTCTSCPKKFRKLVHLKSHRRIHDIKKPFKCNECNQTFLRKHGNFYIYKHILTKLSADLRRHEKIHEGVKPYVCKRCGRAFARKDGLRRHEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U003</accession>
    <name>A0AAD5U003_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4209 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000589">
        <property type="protein sequence ID" value="KAJ3214821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U003"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025209">
        <property type="entry name" value="DUF4209"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039635">
        <property type="entry name" value="ERMARD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31701">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31701:SF2">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13910">
        <property type="entry name" value="DUF4209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4209" evidence="2">
        <location>
            <begin position="114"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="735"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="745"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="850"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="866"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="876" mass="101535" checksum="8AE30E61D796AF39" modified="2024-05-29" version="1" fragment="single">MFSDRVSKVVRLQWKSKGSEKCTVCIETILKSVSNVFLGESISNLCEDKFHVASSIIREEIVTLVPTLLSVYDIQSNLNYLHFFGSKHLCNFELALKSFKTDPFFTILCMFTLIERILRDVIYTKRELDSKKIEPSYLFTDLIVAEDVVTSVGVDMVHVLRVTMGPSCGMNLRNLYWHGFAVTKDFESSTSIYCFLVIHIFVVVCSRIESKLKSIGVSRLSAAPNFDLTAVKGFNISRNLPTLEIEVMSILNSMDSSLLKKSFCNPLLSEAFLLLHNNKWDELARFRFLVVTLPIIEQLLRNAYVEVNKLDNKMVLTANMNEKYIILDTILLPELSSGARNFLINFVGANCMDLMFDLFLSNFGPKLRDKISHGEIFYEDISNSIYSLYFLLIIYLMAILDYKFFISTTTIKDLMRSYYPQYHPYCLCLRNMEDSVLHLRENFITLKNIISINYQVSLMNEPNTTPFSYEENFYSNFFEITNHQFLEEEFMENLAILDSKFRLQKSSKFYVNTKILGYDSDSEGGLNKFHFENYTILVDTFKLDNDTSTYYLIECNFYVKTIKLYNTFKLLEESLISNTTRINEFVTENNFCLSSNAVTPNFTQGYKKKPLILLNRNEKILIIFLRVYFKLYQILEFLFLNLTLLTELPKEVDDTYLTKIPVKQQAIHDFDANFKIVIKRMEILNSKITSCLKPILEISMSGEDDYQSKSGGLGYNSYNYNQSNQQRNNRFSQHSKYSNNARNDNQSTYGNSGSSNYTSYRSNNRNQQYNSSLSSQDNYSDYNTPYESNYNSNTMATASDDADTEATTENVEVALDDLKNVAIMDKKENIEKELDCWSDDSMKEEEEFQTQDYLSGNNNDVSTESYMREEYVEKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0D1</accession>
    <name>A0AAD5U0D1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rad60/SUMO-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000420">
        <property type="protein sequence ID" value="KAJ3217594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0D1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad60/SUMO-like" evidence="2">
        <location>
            <begin position="298"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="498" mass="55931" checksum="B2DA737A62B3CE1E" modified="2024-05-29" version="1">MNFAVEISDSDEEVKEIADEMTELDQKPVAAKLPPGPSKPPSKLRYKTSPKKKLDLLTESDEESTLTEVNSQQSSTTTDESLGNSLQSICENIPVCDDIIMSAPRTSYINDDDSLNGNKTSLKEVSDLTIVDSIVSVREKQSISKSVSPMRSPTPPPATAKINNPSVKNPSHNLKKTAQLVNKIAADLLADLNKNNIENILDPVLQEVLLQKKKDFNENCFSSDSKTKPLTLSIKYSEERKQDGTPRSVNLKDGDVIYCFSVEEKEKWDLKPLTETNNDIDWNEEDSIAKNTDNNLLTLKIRCKNFDPIKLYVNLTSKISAVTATFIKILMEKNPTSFVKKQLTIGSCLLLFDNEILDSNSTLEETDLESDDVIDAKITIIEEISSQQKSVTSQQTLITSQPTMKSSQQTMRSSQQKLDKPPLEFKLCLKSALKSMKIKVNEITPIVIIYKAFHTKFDLKGHENLIFEYKKKILEIDKHVKDYGFNCNEVNIIQVNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0J1</accession>
    <name>A0AAD5U0J1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chromatin modification- protein VID21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EAF1</name>
        <name evidence="5" type="ORF">HK099_004401</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000309">
        <property type="protein sequence ID" value="KAJ3220300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0J1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459:SF1">
        <property type="entry name" value="E1A-BINDING PROTEIN P400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459">
        <property type="entry name" value="E1A-BINDING PROTEIN P400-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="4">
        <location>
            <begin position="203"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="546"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="853"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="898"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="901"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="921"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="930" mass="108286" checksum="17A500730EAA4138" modified="2024-05-29" version="1">MESKRNELLLKKSQQLKKIELRRYTELKSLFQLSQHDFLELDDFIQNYIKKNNVKTSEPKGITNNINLINFKHQKSSPYFFNMNTLTNFSNKKLNQENVFNQNNLLKKKSDLYLKKKNLLNNKNNVIEVVPGPKESKLDINGYQLNAFHMNLNQNSVSNILQNSKKVVLTRDWQLAREEYKYVKLHHRVEHMKSIGLWSFRQILAHVAPERPKAHQDFLLDEMKWLSEDFKQERKWKIAAAYNISRSVMEYHNASDKSIHCVKVKPPNFLTSDDKEYIKVNCQIEEETNINMEDVYSCSDIAISIDPKYIFANPFSNTYFFDYSANDHNKDSDSESKVYRPFKKRRLDRDSDEEEMYQDIFNKNKRVVEVSSLMMEKTFSNLSNRWDDFGRIQSFSPWLKNIKDGNNFSVVPLDELSLEDDSEILVLNGDEKFDHKVILSPFVSPDNSKELEIRPPTPPPTENEEAIEDKMDIMKEENTEQPETAPLKKETPEWTIEEDEYFTTLNTKKNQFSLRNVYQRNKLECYNRYMHLKNEKKDIVTVKEENAKPDLENGTNYNGDNDYNNTTNDANNNSVTNIQTNTNTNSNNLLKKEKIKKKKYLTEKKLEKFFAHFDIIHKFAKKRDNVKLSVNKKLSLAAHDTHLSSQTNAGIILGGNTLGPLEVTALKERRETEAKIREMETQRLYLHCGRPMMMPYGLQQYPMLRPPQQPAGLNGQPVGGNVRPNYNNQMRPQQLPNNYTTEQLKYHQMRMIQMQVQQQNQNLMGSQPNQQLMQGVLRNTSGHMYQGPVGPGRPPMPPNQQQQIQLNNQLNNFNNQIINDPANPNFLLQQRYLQLQQQQSLQQLQQMHQQNLVKNNNGSNPNLTTTSGPNVNTTSSIENASTPAVSTPVITAEELMVTSPEEEKVVEEKTEKVEKNDKSEYSQLNETISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0M2</accession>
    <name>A0AAD5U0M2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000303">
        <property type="protein sequence ID" value="KAJ3220438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0M2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="269" mass="30804" checksum="F1BF1E5DA9E9DF32" modified="2024-05-29" version="1">MSENDEKKSQTQLQTEIKELKDVFGGVKTKATKKNTENPPFPISLTYTFDFPPSNLDVYGICVQLVLGSLEKSNIKVIVNHSDPPFPSDLNKKIEEEILKVWKNFINKNESSFNFIKIFQWIEANHLKLIRLIPEYLIMYMGEDANGTSTRRYEMKPPASNIPEPSDGVESEEDERALEARRLREERKREEEEYLLAEKKKESEKIRAAALAGELDPTFAKPKIASKKEREAEKEARNKQGVRMAKTASKKKKFDPEAAAKLAEARGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0N0</accession>
    <name>A0AAD5U0N0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000322">
        <property type="protein sequence ID" value="KAJ3219893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0N0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF17">
        <property type="entry name" value="AMINE OXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="545" mass="62152" checksum="ABF185078DC30641" modified="2024-05-29" version="1">MNCTSTDQTKPRIAVIGSGLAGLSSAYFLSTIRGSPFTVHLYEKSSSLGMDSGSIEVPCPCVNCNNTDRNSEHFQDPKRVDVPMRSFFPTYYPNLQKLYDQVKIPYTHLTDNSMSFCIYKNAKVNPASIYKLSENFPSNIQTDLKTANNSYDVEYPDLYFTFSCYTLPYFKTVYSLPDLPKFVAICFPFGKMSFVTSSVNHVVSELSKPIDKVFLNTQVTNFKPLNDTTSKCRCIIETNSSSPIEYSHIIFATQANQAAKILRTSASEKSTHLEKTLKLLDSFPYDRSLVVCHMDEKVLPDKENWRCLNFSKVASKKPEMKFYRRPNETENNLNPKFSYKYKNLSQCTHIINFVDKNLDGPKSITGKIFIKFIFIWIFVLGTPDPNSYYVLQTTNPIVVPDVRKTIGVTWYERCIVTMDSVDVVGKFWYGNYFYQKIYLVVKGELKEMEVASTIQILVKRLMEILCKEKREDGLLAVTAGQVIQKSTFGGKIFEFCLKIGIPLLEGCVSSSIKVVESLCLQEGIEFKLPWNKELTKSIDETKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1F5</accession>
    <name>A0AAD5U1F5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006223</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000523">
        <property type="protein sequence ID" value="KAJ3215747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1F5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3215747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23530" checksum="C2B2236B61D668FA" modified="2024-05-29" version="1">MSFLYQNNISFIKSISNPKNLIQKRFEIRPKRVKYKKQQKGFFTVNSGGSLAGTIPQIGEYALQVTEGGRLEDKQLDNARTSIRRCIKQDKGAKVYLTTFPDRPVTSKGSEARMGKGKGAVEFYAKWVSAGAIVFELTGCRKETARDALIRAARVLPLKTKVITAPKEGESRTPPRVLPFFLKQRFKLAEALKYDKKLELNKTEEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1R7</accession>
    <name>A0AAD5U1R7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000328">
        <property type="protein sequence ID" value="KAJ3219741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1R7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="645" mass="72931" checksum="EE20420F4F2ADA05" modified="2024-05-29" version="1">MFKENSSDSEDSESIDLFETLPSFRFKEETKIISLSEHNLNIQHEQSIIKEYIESYIAKCSEIANCQLHPSIVVGLRLIGQNWPYKYIIVGQSPYKSNILPAIATAYAYDTNRCYGFTPSLQVFSQFLAKSGNFDSQEICKRLTLSYCLLEHSICAINARPYVSKDICINTQLESKTSELLHNMIKLTPNSMFNQMLLIPTGDSAVMTVSNAVKSIHVQKRADLHLRVYSTSHPAGIARNSKIVTIMPNVKVSDICKRINKLARVELEGKQSLFTDSGYKMLSEEVQKLQVWHNYSTADLMFMGKYKRLKDFTKYLISLSITLPNMAYVKSKSKSNVSNSYDVNSYVNSILSKMWQIACDSEKALRQDRENMLLLIKKFTTQSDIDDASEILTRMSEVVRHHEKLLAQIRATNHVIFKPNSPHASNSGVVPPLLDTNIQEKRGNEKDKKKKLIIRKVASNNNNKEQTHRADENTPYVLDNTLSDNEPEVGTSQSINKIYNKQNKGKYHIFSNANVDFDVKDNDYNSPSISIALNTSSSTLVQRRARLAALARNMKSAQPTTDEDEIMKLSNSIRTVTVTPPIEKPQDTSINVDEVSASDTSFVKRRRLRTTSTSSITSNTSVSSRLSSINMGSKTKLKIKKYTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1U2</accession>
    <name>A0AAD5U1U2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_003276</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000217">
        <property type="protein sequence ID" value="KAJ3221652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1U2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="13">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="123"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="340"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="486"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3221652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="514" mass="57053" checksum="BBC91C41A12EE1E4" modified="2024-05-29" version="1">MPSFNNFARGNNRYQPYGRGGSTRGGATGSTRFSMDVNHKYEENPVFTDLKEFKKNFYKESEADKLTSAEVQKFRVEHGMTLTGQNIPNPLLSFENNQFPQVINSIFKSNGFDKPTPIQSQGWPMALSGRNVIGIAQTGSGKTLSFILPALIHIMGQPEVVKGMGPSVLVMAPTRELACQIQQVAAEYGKVLGIRNSCLYGGAPKGKQIFELNRSPQIVIATPGRLLDLTQMGKTSLKNVTYLVLDEADRMLDMGFEKDLRKILAQIRPDRQMLMWSATWPKVVQKLARDFLGADNIKVQIGSINLKANNKIKQSVQVMDDSDKSEALGKLLVQIWDGIPGDEATKQMERTIIFVNKKYVCENIANGLWENSWNCATIHGDKTQQERDYALAEFKSGSCPILVATDVAARGLDVADLRHVINYDFPNGVEDFVHRIGRTCRGGDDNGNAYTFMTRNKQDRANAADLVNLMKDAGQEVPAELQSLIQQKRSTSSKWGRGGFGNRGRGGSRGYGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U253</accession>
    <name>A0AAD5U253_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000597">
        <property type="protein sequence ID" value="KAJ3214714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U253"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042239291" evidence="1">
        <location>
            <begin position="19"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="87" mass="9537" checksum="37D757B703A4BD0E" modified="2024-05-29" version="1">MKLSLSTSLLFLSTIVAAVERKCHEKAQYSSGAIPEMPGAKRCYWTSRGGIGGYVVDFWCDSGYDNIVVFDCVYRTGGNNPACLCKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2D8</accession>
    <name>A0AAD5U2D8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000184">
        <property type="protein sequence ID" value="KAJ3222246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2D8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="362" mass="41521" checksum="8D837BC20436A07D" modified="2024-05-29" version="1">MNNSTPGNLQKLSDLLIATSMVSLTNGVQFSVSFLGLIFALSNGSSIKAENINFKHTRLLKILLNFISIFNAILYTIFSTFEPQDKACYYLSFIAELTHHALYIIIDYLLLFRMIKIVCDPFSKTLKIQTYICWIILLTRTALTIYALYVLQIITNKLTGLCSFSTPEYLVQIYCYLDISIDIYATSAIVYKLYSYTHRKENNRAMYNVLVTNILRCFIVTILNILPLILDAILNYMTYERVFIKLLTKYNAFYCDTKSWYQKKKDDKTSKHIESEGLGTSGNGDLSTFHSRFFNSSIPAKQNSNDNSTVQTFIDPAKIYEPEWYISSVELEELQSEVEQQGMKDSKVSIPPLPEINNRASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U353</accession>
    <name>A0AAD5U353_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine-protein kinase HAL4/sat4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SAT4_2</name>
        <name evidence="8" type="ORF">HK099_003607</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000239">
        <property type="protein sequence ID" value="KAJ3221280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U353"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="339"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="84"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="233"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="120"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3221280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="535" mass="59026" checksum="4102C9724F5DE0A0" modified="2024-05-29" version="1">MTSTFSTEIWVSNKAIPSLHKESQGVNSTADSVTANSNNLNQNSSTNTIPKKHNILYRFFHNEEQQQINNSKSQQRQTPFSSIFNLTKDDSDDSDSDIEEKKSSSASSKFLTTSSKKKTNNLPIITKKQPSSNLVNDTPINSINSSQVHTRNNSASTIVCTDDSKIKKPKQPPKLKLNLLHSNLSSTVPKQLHKKNILDNDPDSDMEHEPLSPNFAKRSTSVLFKNLLQKARRPSLNSPVGYSGTSASDSSDGESSTHSVSSTTVHEEHHPTNMFKGLMLGSKYKKSSSSHLLSLAGPPSPSIISMNKIPSVSGETSTESVGSPLVRSNSETSLAEKYGKKEHVLGKGGQAVVHLVSFQNSAKKFAVKEFRKRRKEETQKDYVKKLVSEFCISSSLDSPYIVKTVDLIQDEKSQWCVVMEYCCGGDMYSRIHDGTLTDPNEINCYFKQLVLGVEYLHSMGVAHKDLKPENLLLDNTKRVLKITDFGVSEVFRAPFCSVSQKGKGCIGSGPYIAPEEFGKCEYDSEAVDVWAVGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3D0</accession>
    <name>A0AAD5U3D0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">POR1_2</name>
        <name evidence="11" type="ORF">HK099_004725</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic mitochondrial porin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000341">
        <property type="protein sequence ID" value="KAJ3219394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3D0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07306">
        <property type="entry name" value="Porin3_VDAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.10:FF:000012">
        <property type="entry name" value="Voltage-dependent anion-selective channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00185">
        <property type="entry name" value="EUKARYTPORIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-0626">Porin</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3219394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="348" mass="37981" checksum="C1D7C7E26286AD34" modified="2024-05-29" version="1">MFKSKNENDVEELKKDTQNFLSKVTDSYKDLTSKVSSSYSDLSSKLEDYTKSNKPKAKNTAVKFSFIPPNFGDVNKLSNDLFNKDFPIGATKLELNTNASNGVKFTAIGIKDNKSGQVSSELKTKFTDKLKGLTLTESWNTSNVLGTNIELADTLTKGLKLTLNGQLHPTIGKKNAKAGFEFKQANVYTRAHVDLFKGPTIVTDAVVGNADVLIGADVNYDVTDAKVNKFNTVVAHTSRDYTISVGASNMFGLFSFSYFHRVQPGLEAGARAHWNKATDSAVSVEIGAKYALDIDSFVKAKINNTGVLGLGYYQNLRQGVKLGFGASLDTTRLNENAHKVGFSFNFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3N5</accession>
    <name>A0AAD5U3N5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coiled-coil domain-containing protein 87</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CCDC87_1</name>
        <name evidence="3" type="ORF">HK099_001556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000145">
        <property type="protein sequence ID" value="KAJ3223075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3N5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037383">
        <property type="entry name" value="CCDC87"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16078">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16078:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="828"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="879"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="695"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="839"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="853"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="880"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1109" mass="128958" checksum="DD5D939A5C499FF6" modified="2024-05-29" version="1">MLTERTYRPSSYDEMSEQTKKRSATTEKILEEGDGLEKTTQFLGYDLLLLKDLTDTSQIKKKTIKEQDLNKEAENPEDDIIKRKENQLATTSVQKALKKMALEILDNHKWLSNVEAESLMNIFIADLAARFYTLQDLTFKNFTPTQNRNLVFRIFEKINEVKNFALDKCKKKKRRMDHKNIFDENKNFNRIRGIFRNELLKKINTREIMKEAVREIESGSAIKKSYTGTIQQVTKSEMQERKKFKETLDSVTHPTPALIPIDNSLLYYLQKDKKKKYLEMSAIYPKRDLFSASESGLDIINVPNFTQRFQQMAQKEYNDVRKKSVYKGRRASLIPQTSINNSEETELLNRKKKEEENNLILDEKIFNEKLENEIFRPEPKLEDGSFKYSNLMRNDPLLQSHTEHSLISLKRAQRRKKLDNLVTPRSRYLIPTEEVKNALVGFDYDNFEQDMEQNKLKVLEPINKRDYIETEIESNDVVRTERSKLSIRVPKSIISLQSSVNSSIAFLGNQIDGSAMDTLDVKLRHYKEIEELYEEIMKTIHENFLNAQEENDELVICPTAPNDLEIMSNAFLGYTTYADPKTGMLIPLAGDASEKPSMQSKAAGGALMPSVRLITRVKGHINIPPEDFIKNRKEAMRRITTSRYHGTLKYNLGGYMPKNVVEKNSSLANREEFHIQNYIEFLRVHKTDFVLDILVDEEAEEKQRKKDELRKLKILHEEEEKQRYETAKLEKRKKREELLMYEHGFWNPGLLEVYTEFHDRDVEFGFVKPSEAYLVKKKLELLNNDNFSQSLTNDTLDSSQRKSKSSLYASSNFSNFSLYKENESEAGSEYGSQFGHKSGLSSRAESTNFEYTDSSESEDDEDFQGGQIESAAVSEINIISRESNTNSGSNKSKEKRKRVEQRLLYPLKPAESLIDMDTCQNQLEAIWVVLKMPLDQKIEMAVKYGNPRQALKIDNAINLWKKVARNIAERELILKQAETFETKASDPKMEEAEQRKIIMANLHKIESMLTELIKKISTELKETVTYEGAPYAIKMKVDYLEMLQRLEKKRIRSLNNKTGTRNTSVASKVGPFKLMKSENEITIVKRPDGEYQDPALEEFQNKIKYQYYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3T0</accession>
    <name>A0AAD5U3T0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000126">
        <property type="protein sequence ID" value="KAJ3223528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3T0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052626">
        <property type="entry name" value="SWT1_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16161">
        <property type="entry name" value="TRANSCRIPTIONAL PROTEIN SWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16161:SF0">
        <property type="entry name" value="TRANSCRIPTIONAL PROTEIN SWT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN" evidence="1">
        <location>
            <begin position="45"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="333" mass="38514" checksum="B1E6A7A660691EE6" modified="2024-05-29" version="1">MDLMDLDEVEREISQFRLADKTSPKDLKNDNFNDLNTIESFDNRLMIVVDTNVWITHLETLKKLINTLVLNNIFILVPKMVVREIDGIKKNLNSVGLLSKKVNDYFFESIQKEGTGIIFQMEHETFNEKKEWMEPDDLILDCILYQKKLKKNVILFSKDKNLCVKVKSNQVNFYNFDSERELCGIDLKNSQDDSRISTLMSIILQLFGDEPTSSFNGNSSGSQLNLNNSNNFNENLNMRIRNNISEKSNLKSRSNSNEKLNITKEKDGINFSRCSDGQYHSDPFFSIRLGISDVILNEEYGISFCLLSILPRIFGSGWEYSHEPRPWVPSYVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3W1</accession>
    <name>A0AAD5U3W1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DHH1</name>
        <name evidence="18" type="ORF">HK099_003097</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000208">
        <property type="protein sequence ID" value="KAJ3221803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3W1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17940">
        <property type="entry name" value="DEADc_DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000114">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000364">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="77"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="257"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3221803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="421" mass="47659" checksum="62C1DB4B6B75412A" modified="2024-05-29" version="1">MATNLANQLNNTHISGHEEEDWKKTLNLPTKDLRPQTTDVTNTKGNNFEDYFLKRPLLMGIFEMGFERPSPIQEESIPIALTGRDILARAKNGTGKTAAFTIPVLEKINVNKNNIQALLLVPTRELALQTAQVCKNLGKHMNVQVMVTTGGTTLKDDILRLGQTVHIVVATPGRILDLAGKGIADLSQCQTLVMDEADKLLSPEFQPIIEQLISFLAPQRQILLYSATFPMIVKAFKDKFLTKPYEINLMDQLTLKGITQYYAYVEERQKVHCLNTLFSKLQINQSIIFCNSTSRVELLARKITELGYSCFYIHAKMLQSHRNRVFHDFRSGKTRHLVCSDLLTRGIDIQAVNVVVNFDFPKNAETYLHRIGRSGRFGHLGLAINLITYEDRYNLYRIEQELGTEIKAIPPVIDKSLYVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4B6</accession>
    <name>A0AAD5U4B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000354</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. TRA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000108">
        <property type="protein sequence ID" value="KAJ3224028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05163">
        <property type="entry name" value="PIKK_TRRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046807">
        <property type="entry name" value="Tra1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046805">
        <property type="entry name" value="Tra1_ring"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF1">
        <property type="entry name" value="TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20175">
        <property type="entry name" value="Tra1_central"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20206">
        <property type="entry name" value="Tra1_ring"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAT" evidence="4">
        <location>
            <begin position="2422"/>
            <end position="2986"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="3">
        <location>
            <begin position="3248"/>
            <end position="3532"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="5">
        <location>
            <begin position="3537"/>
            <end position="3569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1872"/>
            <end position="1909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3002"/>
            <end position="3048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1872"/>
            <end position="1887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1895"/>
            <end position="1909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="3005"/>
            <end position="3016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3033"/>
            <end position="3043"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3569" mass="405943" checksum="D9D71A723E33472F" modified="2024-05-29" version="1">MDIKLKAVVELRGRCENFIVTILSNKNKSIEIVQTADYQRYLTALMPAFLHFLSTTQPTFQSEEPVQKVRLLILEIITRLPNLEIMRQYVKELMDILLKILKEDNEDNAVVCLKIITDLHKNFKGYMEKTVFLPTPVPAIDDGKHPNRTLGKSIQSFKVLTECPIIIALLFQVNRKIVTANVDELIKCVISALKLQPHQQKQAHEEAATKGTVFYGVSPLIKNRVAYAELKALQIKVTFILKYFINSFAPHVQDIADSVVSLMKDCPPDCSSARKELLVATRHIWQTEFKFYFLTHIDVLLNENVMTGTGVTCRETLSSFPVICKYHRKKISHLNNVSGDLSTSNSEHDSENLTVLPEYQGYLDLGFSQPIKTSTNPMDSNADLVKDIRFLLKYIIPGIKTVLISIAKCNPVTNNLDPEYNSIARGFCDKEIEIFITIARDGLFCFNYFNLDQFDENGVFLTNSDSSASTSSPSVDGIVTTKNNSMSSNAVNASNASKEEKESLEGFAAIFKSIEPSVFQEVFGSQMGYFFELALINQQLMAVPQYFLATASVSSNFAGLLLRYLIDSLDKLGSDSGYAAVMLKIFKVLFLAVSIFPEKNEPVLLHHLPNLILTALRLAKKAIEPLNYFLLLRSLFRSISGGKFEKLYQAVLPILPILLETLNNLLATTQRVQMRELYVELCLTVPVRLSVLLPYLSHLMKPLVLALHGGNELVTQGLRTLELCIDNLTHEFLEPILSPVMNDLMNALWRHLHPEPYSRQHSVTALKIVGKLGGFNRRFLKDAPNLKFVKQDSGLELPFLFNPLTDKPVKVSLNETLTVICDTLKSGTAKPFYISQCFEFLKGCIPLLIDTDTGPDNLGHILQSHIEQYVSNRSTHDEVEIMKDGTNPFPIENTTPQFLLDAHVKVLEDVFVGLFYAAINEETRAESRAIINSLCRHFALLSISELVNGEKKAVPSTGKTNLDAIISTPSTRIDSFINGIVSVMSSPNSDIQELSKEYFGSFYNTCLTFLVSKEAVEDMKIFKTFASKFCSACYEGEWFYKRGGCSGILLLSTQLGLSHSWILLHEIEFVKALLFVLKDTGSEMTIINIKEATSTLLHVLELCNKPLKDEQEKLPKKMNNLVALLIGELSNSNQVVRETIQKSFDLLAELSGIDVTELLLPSRERLLSPIFIKPLRALPFQMQIGHIDAITYCLSLRTPLLVFNEELHRLLQEAILLADAEDAALIPGKNLFKNQGVVTNLRVVCIKLLSAALVFSDYSNRRLNTTRARIISVFFKSLYANHPEVVEYSNKGLQQVLATQHRLPKELLQAGLRPSLVNVSSPDSSKLTVSSLEGLARLLELLTNYFKVEIGRKLLDHLRNLAEPALLEEASSRPLSEVEKINVIVGIINVFYLLPAAANCFLVELINSVLGLEEKLKRFRSSPFRLPLIKFLNRYASESIKHFYSQISTSVGHNRLLIGVLGSEHADVLRAEVMKSTDLFISKTLGSPSAEANYHGVLMMKEITKFHPEWLLENKALITILKELWKTQIEKKDFKAEYSMNPMMQSILELFVLYLENDSSETSLLFDMIDALDLDVCVEQDGIKKFIYETVALKYSVILKQNILDSFFIVFQDKSYSRAKVATIIRMLIIPMLMVHSDAHFVEVFGSKVSLMDKCVWQPLASEKVEYYSDTTMIVELLQLTSLILQRGRQIVNEFKKNIIKFSWNYTNKVEEITCKQAAFVVIARFIVEFPTLGSIISKTFVELLKTHQPEVKNLVRQAMDSLLPILPSRTGTETGRDALFWIAWTRKIMIDDAHSSSQLVSIYQLIIRHSNLYYNKRDAFIPQIIGSLSKLGLAATSTKETKILSIDLAELIFNWENQELSSTTIIVPQTPLVPQTPATPQTQVDEPTSKRQKFSISTGESQGSKSQTSNYRDMLVTYLIRFLLNSTHEPISKGELASRVAKLLEDILNRWPECNIKFSLFDKLEDKSLSESTILIINALEIFLMIVKVKDDQWLISNIAQFQNYLNPYIKSDNILVSKGLKPILSKIFQAVANNTSDAHYPKEVADFVKNVDVTIRSNLGQDNLKPYSTIVLLCTSYLNRKAEITMWYQDIMKLLQKLANEHCSNAVDMEGKDANSEMITMLLSLLKTKTSAMGEQRKTFLNSLLLLIEKSKDTNLLKNILSIVSDWIYAKAEAFPTQKEKANLMVTLLTFANREDKSLLEDYLELVAKIFSDSSFLRTELSVRLENSFLIGTKYSNPITRKKFSKIFNDSVDKLLSTRLNYIFGVQNWEYLSSDFWICQALDLLLGSAIKNVPVFSSPTYYKLYSIASFFQTSADEMMSTDTNEAVTSIVLEHQKFLLSLQSITIHNEKSLAFSLWSQIFPICWELLTNRERHDLTKSIIFLLSKDYHSKQADVRPNVIQCLLEGIRRSVPHILLPPQLVMFLSKTFNAWFNGIELLQCMIVDLKTGNASKYQEKVRDSTLDNLADLYSSLNEDDYFYGLWRHRCQFPETNAAISFEQNGMWLTAQNFYEQAQQKARLQPHPFNESEYNLWEEHWVLCSKKLQSWDILTDLAKQDVNCDLLIDAAWHTVDWCSESETIKCILGGVTEGNQKKQIYEIFHFLTKMQAENESDRVKFQGLCDNGMQLALKQWQSLPEIVSNAHIPVLHSFQQFVEFQEAFAVLTNLSQTNPQNVEVKSTELKGTLQIWRDRLPNIWDDINLWSDLVSWRQQIFGIVNRAYMPLLPSLSIPASVPQSSFAYRGYHETAWIINRFAHVARKHRLTDVCVNQLTKIYTLPNIEIQEAFYKLREQAKCYAMNPCEWPSGLDVVNNTNLMYFIVNQRAEFFSLKGVFLSKLKLHEEAVNAFSSSVQIDTSLPCAWAAWGKYNDQLFKDAPKEKEKESIKHAADAINCYMHASTLYNSGKSRKYMSRILWLLSLDDETKSISKAYSSYKSETPTWYWINFIPQLISSLSCKEAAFAKDIILRIAKIYPQSLHFHLRTAKEDLAVQKKQFTMRMTVATAAESHSTDNSQSQAPMPATENKPSLGGDMGDTAKEGEKEGNGDLNQCISTDASAAMTTDNSATSTEQVQKRPMNSWDYVEEIMGLLKTAFPLLALSMETLADQIINKLKPTTDEDIYRLIIALLNDGISQLARDPEDKSGLSPATETNLQKFAETMAPNHLKYKAAFENDFIKSKPTLTVLVQRFREWRNKLETLLDNRPQKQRLEHFSHYLVEFEYQKFDQVEIPGQYLLLKDSNRDFIKIERFLPEVILVRNNQGMARRLTIKGHDGSLHPFSVQQPAFRQCRREERILQLLRLGLYKMIPLTCLYWKFMMTIVAKRECIRMKDIMQTEDIKQKSKVDLLNLKTEVMDEIGSKMIPEFLLTQFMSRNMKNSSDLWFIRKRFTTQMSAVTFFSYVLCIGSRFPGKFLISRETGNIWCCDLVPSLSNSTMMFTNQEAVPFRFTPNIHHFIGPIGVEGVFTSSLMAISKALTECDMENYLSIFIRDELNACQSISKKPLFQESQIKDLVSANVDILTRKAQALACTAEREKFDKECNIPANQTILDLISQAVNPLKLSQMDLAYMPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4F6</accession>
    <name>A0AAD5U4F6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine-protein kinase KIN2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">KIN1_2</name>
        <name evidence="8" type="ORF">HK099_000447</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000110">
        <property type="protein sequence ID" value="KAJ3223963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4F6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="29"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="176" mass="20207" checksum="E1BC55139B1903E2" modified="2024-05-29" version="1">MLNSSSISKQPSHSHIKSAKVIKGTKGNWILTKTIGKGSMGKVKLAINETTKEKVRPTTSIRDIPAANHYKNLQQDQAKEFRIIREAAIMLLLDHPYIVTLHEILLIDQYYYFVFDLVSDGQMLDFIISHGKLKEKVARKYLRQIVSAVDYCHQNSIVHRDLKIENILIDKEGYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4P4</accession>
    <name>A0AAD5U4P4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003203</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000213">
        <property type="protein sequence ID" value="KAJ3221714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4P4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="62"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="16399" checksum="92DFBC2AB73C99A3" modified="2024-05-29" version="1">MFFTTVLRSQTSSINHVKTVWERMSKNGFNGLFTLDIITSDSKSGTITARFLVDKNHANMYETLHGGSIASLVDIAGSLAIASKKTTDYTGVSTDLSVSYVKGVKLGETVTIISKMQSNGKTLAYTTTEFLNDDNEVVAFGSHTKFIKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4R8</accession>
    <name>A0AAD5U4R8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 33A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000096">
        <property type="protein sequence ID" value="KAJ3224336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4R8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043155">
        <property type="entry name" value="VPS33_dom3b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="67523" checksum="ABD969795AC74927" modified="2024-05-29" version="1">MSISSFALKEFAKKQFIQVLDSVRGRKGLVLDKQLSGPLSLIAEFSLLKEHGVEKIYHLQKSKLETECKSLIYIVRPKIQSMKWISEQIKYFVSLGLKLDYHLFFVPRRTLVCEMVLEAAGVFGSITFGEYHLDLIPLDEDVLSLEYDSAFKEIALNGDTTAIYYLAKAIMNLQTIFGLIPKFCGKGNNANILSSTLLKMREELVSDLDDPAIQSKIFPPTSDFESMIIIDRQVDLVTPMCTQLTYEGLIDEVFGIKSTFVELDQSLIGTQQQPPGTSLATSSTNVSNKPKKVPLNSTDKLHFQLRDKNFAVVSGLLNQIAKRISDDYEGRHQAKTIGQIKDFIGRLGGLQAEHQSLRMHVNVCEQISKYTSEQEFHKNLEMQQSAVSGLANQNHLDYIEEMIGKQRPIQQILRLLCLYSLVNDGLKVKHFDFMKKEIVQTYGYEQILTLQNLQKVGLLKKQVATSSLALAKSNNFPSIRKSLRLIVDDVNEHTPNDISYVYSGFAPISIRLVQLATHKLVDETKKLDANNNNNVIGWKNWEDALKLLNGVTFEETQKTFEDFLLPHKSRREFVVVTTNILNGTTLMTELMHNEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4W4</accession>
    <name>A0AAD5U4W4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000086">
        <property type="protein sequence ID" value="KAJ3224641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4W4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="221" mass="25326" checksum="17168DB71B92332C" modified="2024-05-29" version="1">MSGLSFNLKTKALQKHLRKKFKPEVIEFTFINGPIKIIDEESDGEEVFTWLNRAVTSEHDTEVVRLSGYQFTFDYLDQIIVKEGPFDGIFGFSQGSHIASVYLAYLQSNNSKTMEALKFFVAISGFYERRAQDYLDDTLVDLKKNLPIQIPSLHVYGKKDEVITMDLSEKLAENFLEKEKSIYIHNGGHLTPCDSASLKHFTNFLCKFTCQSECIPKKNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U574</accession>
    <name>A0AAD5U574_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH dehydrogenase [ubiquinone] iron-sulfur protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NAD7</name>
        <name evidence="7" type="ORF">HK099_004351</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000302">
        <property type="protein sequence ID" value="KAJ3220445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U574"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.645.10:FF:000005">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="entry name" value="Cytochrome-c3 Hydrogenase, chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004739">
        <property type="entry name" value="PRK06075.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NADH-quinone oxidoreductase subunit D" evidence="6">
        <location>
            <begin position="153"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3220445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="423" mass="47993" checksum="8B49549F95B0046B" modified="2024-05-29" version="1">MTPTTYSVTTRWFVPPKTRQLTEQMIVPIRETTGLHMENFTLNFGPQHPAAHGVLRLILEMKGEFIERADPHIGLLHRGTEKLIEYKTYVQALPYFDRLDYCSMMCNEQAYSLAVEKLLNIQVPRRARYIRTLFGEITRLINHILAVACHALDVGALTPFLWLFEEREKLMEFYERVSGARMHAAYVRPGGVALDLPNGLLEDIHKWASHFAGRIDETEESLTNNRVWKNRLLGIGKVTSAQALDWGFTGPMLRGSGIPWDLRKEQPYDAYDEMEFDIPVGTNGDSYCRFLCRVEEMRQSLRILDQCINKIPAGPIKVDDNKIAPPSRSTMKESMEALIHHFKLYSEGYSVPVGETYVGVEAPKGEFGVYIVSDGTSKPYRCKIRAPGFAHLQGVDFMAKGHFLADAVTVIGTCDVVFGEIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5I4</accession>
    <name>A0AAD5U5I4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Decapping nuclease</fullName>
            <ecNumber evidence="6">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DOM3Z</name>
        <name evidence="8" type="ORF">HK099_000644</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside-ribonucleotide in mRNA + H2O = a (N(7)-methyl 5'-triphosphoguanosine)-nucleoside + a 5'-end phospho-ribonucleoside in mRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66928"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17313"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:172876"/>
            <dbReference type="ChEBI" id="CHEBI:172877"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:66929"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60880"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:60881"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78683"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78684"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DXO/Dom3Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000116">
        <property type="protein sequence ID" value="KAJ3223814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5I4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034353">
        <property type="term" value="F:mRNA 5'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110155">
        <property type="term" value="P:NAD-cap decapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013961">
        <property type="entry name" value="RAI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039039">
        <property type="entry name" value="RAI1-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395:SF9">
        <property type="entry name" value="DECAPPING AND EXORIBONUCLEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395">
        <property type="entry name" value="DOM-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08652">
        <property type="entry name" value="RAI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RAI1-like" evidence="7">
        <location>
            <begin position="30"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="381" mass="44416" checksum="A1AD0D3712C88ED2" modified="2024-05-29" version="1">MKRNLNSIKETFTINQQQHYVKKNINYQFPLEISHFSYDENRVVSVNDRSGLKYFYEPEKNSDLNSGFPDLFIKREPKLEHLDSLIKCLFEVNTNLKKVNKSVYAPNFCTWRGIIRSLMVTPYFPKDSWELNIISFDNTIFMEENETLERKAASYGETEKEVKMSYYGYKFENIATISKPPSDLKKNDQELTDRNSEAVNTNVQYCSVWKSSLGTNSMILGGEVDCLYSENLVEHNHQKHYAELKTNKVFQHSWQRKSFERYKLLKVWAQSYLAGVPTVIIGFRSDEGILKFVKTYKTVEIPSMVNSWNPHVCLGFLDSILNFIKTNLEDVNDATQIYKLKYDSLQPHAIKLEGPIAAENNLCFLPQYFVNEVSQNKKNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5J8</accession>
    <name>A0AAD5U5J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002834</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000198">
        <property type="protein sequence ID" value="KAJ3221971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5J8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000182">
        <property type="entry name" value="Cytochrome P450 3A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF175">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="69"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="186"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="377"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="712"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="906"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="962" mass="113164" checksum="2D3D108348B30968" modified="2024-05-29" version="1">MVFKCCSKIHTFINDYIAESYSIPRIATKTTVVAGTSPNSYPFDSLTQMQSIHNTVTPEQLLYTQSLINNDKENMRNDLLEKKKELHQQSLNTVKNWENTIMGKRKKRLQNLEEKKIVAESIKQKIDEDWKVLQEKEKSEFLNKVKRIREQQTASFRNLNSSLLIQEVKMERDLQLKEKDRRNKYIAEAEEMFKKDSKELAFLKAKKEYKELVEARERRHEVAKFQVNQAQKKLESEKHEKEDLEILKINQKRIEDIEREKKNSKIEKQKKVEEYAKCLDMLTEENNLKNLNAKLIDNKILLETKKFNSLKQFLENKKKDINKKNIQDRFEFIEKIGERQLSEAKRKELLMDKFFDQILHFKEDEPEKRRVRELEKVKKYNAESKAFREEKKILDSEAKKVEKLNNETIMEIERLKLEKEYIKQKENQQTIKQHLKSNFNYNKLKVIENLKLLEEKKLKEKLNENLKLDELNLELKNFENYGKEILEEYNDKGPPSAMWTLIGNLQTIMNEDNLAPHRRWAAKYGNFVKYTSLFNKGRVLVLDPKAIQRILVTAPEIYERQSEGDFFNYVIGPGLLSVHGGDHKRQRALINPAFSYKNIKNMSVDFSVLSLDLKRKWSDLIKTNQTIDILPEVSKFTLDVIGRTGFGFEFNALKDEHSDLHEFYETVLLQTELSPFLILESFFPFLSYLPTKRNREFKKCVNGLHKVVDNLIIEKRKNLEQKKLENNLEEEKDILSMLIKANESEVASKKLSDAELKGQVGTFLLAGHETTSVALSWTLYYLALNPDIQEKLYVEVSKVLDTKDSFPTFDQVNTQMKYVDSVIKEVLRLVPPAPITSRVTTQDDELGGYMIPKGTPIILAPGVIQRHKEFWGENADEFVPERWLETNETSKNIAKFIPFLFGPRNCIGSKFALIEMNIVLSVLVKNFRFEQDFDFPLKDVKKKIRITWKPEPGIKLKVFERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5K0</accession>
    <name>A0AAD5U5K0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine/threonine-protein phosphatase PGAM5, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Serine/threonine-protein phosphatase Pgam5, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PGAM5_1</name>
        <name evidence="5" type="ORF">HK099_000913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000123">
        <property type="protein sequence ID" value="KAJ3223621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5K0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090141">
        <property type="term" value="P:positive regulation of mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051021">
        <property type="entry name" value="Mito_Ser/Thr_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20935">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20935:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="221" mass="25870" checksum="356CCB4527E2B698" modified="2024-05-29" version="1">MQFQEKSKWDYNWDRRHFENSDKKIETKRRNIFLIRHGQYENKVHDSERVLTEKGRIQAKLVGQRMKEMKFTFNKVWVSTMVRASETAKIIESCFSEPLPIEHSDLIREVCPADPVPPLEGYDPAESELFQETICAEAGFRQIFHRPDVKDPAVSYEMVVCHGNLIRYWTLRALQLDPQGWLRIGVHNCSVTWITIAEDGKVSIKTLGDFGHLPKEFQTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U604</accession>
    <name>A0AAD5U604_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TCF25</name>
        <name evidence="2" type="ORF">HK099_002297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000175">
        <property type="protein sequence ID" value="KAJ3222443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U604"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006994">
        <property type="entry name" value="TCF25/Rqc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684">
        <property type="entry name" value="NULP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684:SF0">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04910">
        <property type="entry name" value="Tcf25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="706" mass="81659" checksum="0B6F235A1E27E91B" modified="2024-05-29" version="1">MSRQLKRLQKEKEQLFFNDVVEQTALEESEDDETIKPKMNSFLHLFDDQMSNENDLIDEEDEIVNEEEVPPVMPTKQKVKKSTKKKGNKASKSNKVKENVSEDNEFDDFDKTLKELSEKYKNSSIEPPKANRKNFLKLFQVDTKNLNPTSEMRRIFGSKVVNDALERNQRNQLRSGRGVKTLAKRTYLAQSNDTWPRIEKQLGLDMELIENDLETDTKLFTFTHSKKYQEVQKKFLDCQLTHDPNTIAHLLRMHPYHIDSLLQLSEVSRHNGNMNDASELIEKALYAFENAFHSMFIVASGKCRLCFDRVESRSFFLALYKHSILVSRKGCWKTSYELTKFLLSLDLDNDPMGCLLVLDLYSIKSQMFEVMIVMWDAAREIGKNLGGLNCFPNWWFSTALAKKELHGEDQANCILEEALLTFPYFITKLYNKLGIVSDFQINPYFFYKGSGILGDDKESPILTLIELYLERSSSLWKEPENLEWLKKVFNGLHSDLKHRNLKTFVDFRLKLFKNTEFDLPLNIKRHVYISELNSAVSNLPLSSIGSFSVNDPLPPETAVASVYDVYLQERARASNPFAGAGVASGFVRSLLPWLNIPNNIRDLPQQRREAVNVVENLNQEEETIRYVEEAIRRQGQEGRLPGMFPEGAEEQESWISSIRDYLFQSRLFAASQNNAEESTPDLEESIYVEEEDAEEDDEDLMGEVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U611</accession>
    <name>A0AAD5U611_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MCM6</name>
        <name evidence="15" type="ORF">HK099_006259</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000053">
        <property type="protein sequence ID" value="KAJ3225759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U611"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="412"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="743"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3225759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="893" mass="101465" checksum="2BE5B524BED648C2" modified="2024-05-29" version="1">MLSDGLPLPSQEMSRMSLMSDPMSEDVEEAIDNAPKRSKNLSKRRNDLPLNVLREMVPQILDDLGEEIKRDFQIFIETFSEYDENEGEPVYKYLEQIKNFKHDGRTTLFVDLMHLFEHNEQLCELITKKYYRFEPYLRQAIQLVIFKHDKEYLQSSDLYQISAGEDLPMKEFWVSFYNLAHHTLNIRCNSIGELITIKGTVTRTSEVRPELLFGSFKCDECGQFIHDVEQQFKYTEPSTCHNTSCNNRKIFTLDGERCKFVDWQKCRIQESSDEVPSGAMPRSMDVIFRNEIVDKAKAGDKVLVTGIPIVVPDVGQLFAVNAETRREIYGRGRDGFGSDGITGLKALGVRDLTYRIAFLGIFVKCENDKVSGAANLEKNKDVSIEESSDEILNSFTQHEVEQLEVLKKTKFLQHKLINCVAPHIFGHEDIKKGLLLQMLGGVHKVTQEGINLRGDINVCIVGDPSTAKSQFLKYVSGFMPRAVYTSGKASSAAGLTATVTKDEETGEFTIEAGALMLADNGICCIDEFDKMNLVDQVAIHEAMEQQTISIAKAGIQATLNARASILAAANPIRGRYDKKLSLRQNINLSPPIMSRFDLFFVVLDDCDEMTDFNIASHIVNFHKAHGDENASANVPEITQKSFHNYLKYARSIKPLLTSNAREYLVDKYRQFRQEDGAGIDKTSYRITVRQLESMIRLSEAVAKLDFSQTIEVNHCMEAAKLLRTSIVTIDQDNIEFEEEEQRALLPNEESYPATDKADAGASSAKETTEAKSSQSQQKIKMDAEEYNRIVKLILQKIKANEDDSLEKGIKTSELVEFYLEVKEDEILTQEDLIKEKKMILLVLKRMQKKDGILMEISDFEMMTTNEKDGELKEFKKKVAEDPVLTIHPSYYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Y2</accession>
    <name>A0AAD5U6Y2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyrate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001040</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000127">
        <property type="protein sequence ID" value="KAJ3223509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Y2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000006">
        <property type="entry name" value="3-hydroxyisobutyrate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011548">
        <property type="entry name" value="HIBADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01692">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981:SF7">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22981">
        <property type="entry name" value="3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="9">
        <location>
            <begin position="4"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="10">
        <location>
            <begin position="146"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="281" mass="30167" checksum="1C7E8C39E17A0949" modified="2024-05-29" version="1">MYWQMGYPMAVNLTNKAKNSNAFFVNDFNNSTLQKFVSENNHASKQLTPKALASQSKLIHVREVYLGANGILNGVSKDPKTSKEVAECAKAQGCIMVDAPVSGGTLGAEAGTLTFMVGSETIDYFNLVKPYLQMMGKNIVYCGTNGNGQVAKIANNMLLGISMLGTSEAMNLGVRLGMEPKLLANILNTSSGRCWSSDTYNPCPGVLPNVPAARDYEGGFGVTLMAKDMGLAVQAANESKSTVTLAAVAHQVYNQVGSTEGFQKKDFSSVFKWLNDNAKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U700</accession>
    <name>A0AAD5U700_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U700"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="299" mass="33662" checksum="60332918824AAFAE" modified="2024-05-29" version="1">MAADDTSAILPGLNVENFQWGMLMSCTFLNLLFSVKYVFMNKTGKLPFFIQLTWFISQIFWINYYFSDKSSVECLYYGIFMAIFDTVAKMLLVWYINVRLEVISSVNYQMNILRKIFVLGGLLTSILSNVLNWLPTWMNQELGWLTHAMAMALYLSADIIIAVQDIIVGILFVGKISNSNTFAEGLHYLRNTQEIKFVAVILSGSLIGSCVSFILKMEGVDGSTWAIYATYFAFKASLTAFSLELLVQFCINQDKSQRSEGTLKKVNVVESENVTDTKSTQTQFSAIESSSGAGERDMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U751</accession>
    <name>A0AAD5U751_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003621</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3226998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U751"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015910">
        <property type="term" value="P:long-chain fatty acid import into peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042760">
        <property type="term" value="P:very long-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF67">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="289"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="567" mass="63926" checksum="5DAF6FE36CCF0105" modified="2024-05-29" version="1">MGNNNYFKAINLDTRLGNTADQLITTDVKRFCDALASLYSNLGKPVLDIVIFNYQLVRNIGSRGMYGILASYIVTATIMKAITPPFGKLAAEEARLEGNFRIAHSRLITNAEEIAFYNGSEMEKTILDRTYSQLIKHINHIYKIRIAYNMFEDFLIKYSWSAVGLIMASIPVFFPEYAGSAQIEREKILDKNNAGSDILDLKQGSRTQGFITNKRLMVGLADAGGRLMYSYKELSELAGFTFRVYSMIQVLEDINEQKFVQTSGMKPEGEEVFDINKIEGVTEYGHEGLHFKNIPIVTPSGDTVLVKDLNVDINPGDHIMVTGPNGSGKTSILRVISGLWPVFRGVLKRPSIGINEIMYIPQRPYLSIGTLRDQIIYPHNFEDFQKSGRTDKELFSILKTVYLDYIPEREGGMNAVKVWKDVFSGGEKQRIQMARLFYHHPRYVVLDEATSAVSPDVEALMYGSAQDEGITIITISHRPSLFKYHTLLLKVGEGEKGKNWILESISSSNTLIESVDTEIKKIEGHLSDVAELKERLNEINRELKLNVPLVGNDDDDKELKHAKRTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7D8</accession>
    <name>A0AAD5U7D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002431</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7D8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040176">
        <property type="entry name" value="RNF121/RNF175"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13407:SF0">
        <property type="entry name" value="FI05221P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13407">
        <property type="entry name" value="RNF121 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="234"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3227365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="360" mass="41812" checksum="F578E2875D6022C0" modified="2024-05-29" version="1">MADAVTETFVAVLPSIIIDNQGRQHSIDELTDQQKSLLKEKIIFQHEHAGHEETHARMGLILLTALISVQFLIMFWKKYHKKSFDWASLMGLLIVPPLLAINAGNYRYLIIWFLFALTNFFVVRLAFEKPLRNSTPGFVYRFYAWTYTLSYIIGFFGLFITISALFRLPEKLFSIKEQSEIFMFQGGLIMLFYGLYFGCLGRDIVDRLSEAMAASIGYYNRKGFPAKHLRDSICAICGLTTTNAKQAEYINPTEEKNLFWWFNGILGHYGQTKVGNSYQLNCKHIYHESCIRGWTLIGKKDCCPYCKEKVNLKVFSQGSNPWDTTQLLYLNLLDALRYVIVWNPMVFFIIHYVFIIFDMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7H8</accession>
    <name>A0AAD5U7H8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carbohydrate-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000051">
        <property type="protein sequence ID" value="KAJ3225827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7H8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09620">
        <property type="entry name" value="CBM9_like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010502">
        <property type="entry name" value="Carb-bd_dom_fam9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039367">
        <property type="entry name" value="Och1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31834:SF1">
        <property type="entry name" value="INITIATION-SPECIFIC ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06452">
        <property type="entry name" value="CBM9_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate-binding" evidence="1">
        <location>
            <begin position="160"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="345" mass="39411" checksum="24F43CB590F5341C" modified="2024-05-29" version="1">MFGVEADTILEPCTSGKYGKCFARPLQFTQWTLVSTSKHQLITEIVEEVSKALLVYDGHFPTVWEILDLTGPGIWSDVIIKNLISRTGKKLEDFSGIKDDITVGEDLRMLTITGFSSGRSPPLMGAHPRDHPLAYVAHKFMGSWKNEQYKCKKTSVIPPLDGRLEGAWDTAPWSTDFSDKTTHEVLKPRFKTNFKMLYDNNHLYIAAKIEDPHIWANLEVDNYERKLSQYVELYINPRRNGKNFYKFEINPVNEIKESKQGGTESPIKISGLQHKVHINGTLNSPQDIDKYWSFTIAIPWDGLSDLVDNKVTHTPPNVNELWMIDFSRELDMEWFKTSTLGISGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7L2</accession>
    <name>A0AAD5U7L2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">propanoyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Propanoyl-CoA C-acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.176" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7L2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00829">
        <property type="entry name" value="SCP-x_thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055140">
        <property type="entry name" value="Thiolase_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006102">
        <property type="entry name" value="PRK08256.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42870:SF1">
        <property type="entry name" value="NON-SPECIFIC LIPID-TRANSFER PROTEIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22691">
        <property type="entry name" value="Thiolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thiolase C-terminal" evidence="6">
        <location>
            <begin position="279"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="502" mass="54785" checksum="3E03C6A44273E654" modified="2024-05-29" version="1">MSNKVYVVGVGMTHFDKPGRRKDVDYPDYALEATTKALLDANITFDDVQFAAGKYFSLFDLFAQLLFILVGYVYGDSTSGQRALYQLGLTQIPIINCSTGSTAYYLAKQSVASGQYECALALGFEKMAPGSLASVWEDRTNPMDKTIEVMNELREMTPAPFAAQIFSNAGLEYIEKFKKSDLAMHLIAEKNHNHSTLNPYSQFKDKYTLEQVQKARKIHGSLTLLHCSPTSDGAACAIIASEDFVIKHNLGPQAVEIVGQSMATDSILAFDPTGNSKSMIEVAGSDMTRRAAADVYRQAKINPKEDVDVVELHDCFSANELITYDALGLCEHGKACEFMESGATTSPLFDRPSVKANPPKKRIIVNPSGGLISKGHPLGATGLAQCAELTWQLRGWAGARQVPNIKNALQHNIGLGGAVVVTCSRNPEPNSKILSSHNIKRWEDPRKRFGYNPAVEARPVTESQVRAVMSYRGGLSGTKEKLDDKYAEHVGTTIASGNTARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7U1</accession>
    <name>A0AAD5U7U1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008287</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7U1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042095061" evidence="3">
        <location>
            <begin position="20"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="947"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1036" mass="114873" checksum="379800962167B7CA" modified="2024-05-29" version="1">MIFLSALIKSFFFLTYIASQQSLITTPTNLEEVIGSPLDFLSDKNSNLYTFSLTSNCASSSNSIGILISKFKNSIKPTWNVQICPSPSEKKLTLLSSSYDEINETIYLSYKTQRQVIVRSISGEGTPNPTPISVSSADVTIPGVIKAFPLKDSATSKVFLLSESNVYILTRNGTTASAALLKKLLLNTFATTMEVVEDRIVVVGYITPAMMNITGTVEENSIGIFLQSFSISDPLESRIETFKESENLRIFQKSNVIPSIPADTKDLSDDTLSVNRKSILTCGEYVFFLFSASSADQEVAVYQYNKNPMRLITYKNFDFNGDRYISATCIDNVVGSAVKTGLLLLVQSGKTIDGLTSQYMVFIDTDLERSRSPLLVDKQILNLKSFSTLRFSTADVVVSSNATISRLLFGYSKSLQKPTLNAVFGVMATTSEPLLSVLIDTSCSLNMYFDTTSESCKTCNPSIAACFNGVQSGRENDGGLSLTDKVAIGVFVPVFFLACLFLFLIWYRRSENKTSDGFYSSDYYAEEKLKKQPSFSKPPSDFTKIISLGNDWDTDENPGTYEVLQPTVEVNESVKRKNSEKYLKISNTATASVVKKDEAITNLIKRNNSNHIKQKLPEEMVISQPTLISSSTLNRSPSHTYTLTPIVHQEENKNNDTNYNFLSERVSTLHLSNESHQKQNPFSDINALNAQPSQSVSTVSKPPIAPAVEENLWTQMPNEMSRRGINENHLVHQNQSLLPKERKPLNQSVKPIGTEDLENLINALDEEDRMSTLSRAISYAPSWHNQPYYAATEVSFDANTAISNGTTSKNDNTSYSRKEEFNKLINLNNSQSANSRSRTFSTPVIPTREATGNSLDNLSKNVNSLKQQLNSKPPLPHSSSFSLQRSQNASENISQKKFSWAIVNNAGSRSRTTSNGSSLKEKHVSFDKTEKSGMNFGSHKRFGSIDSILKNNSLPPPPVPLPISKSPPRNNRESQMSVSPKFSDAGSLNRYHDFEPFAYDSNDKEFCTVAEGVTETGKKRESVLSDYMSSIYDGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8N2</accession>
    <name>A0AAD5U8N2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRELI/MSF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000113">
        <property type="protein sequence ID" value="KAJ3223902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8N2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037365">
        <property type="entry name" value="Slowmo/Ups"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11158">
        <property type="entry name" value="MSF1/PX19 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="126" mass="14522" checksum="93798C2CC9A445D4" modified="2024-05-29" version="1">MKSTIRNFQAVSEAVFRKYPNPFAQHVYSNDVISRTVDDNGDVWVLEQSIVDPITLSMKTITRNLSHTKLMLVEETQIIKPHPINVSWTQVEASARIISNVSWSSLRSSVERYGFYKGKDNMIRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9B8</accession>
    <name>A0AAD5U9B8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat-containing protein 70</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006033</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9B8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051858">
        <property type="entry name" value="WD_repeat_GAD-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017">
        <property type="entry name" value="GASTRULATION DEFECTIVE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="67"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="118"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="408"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3228153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="49284" checksum="2CDAFEA90C07F6F6" modified="2024-05-29" version="1">MDGNFRPFLTAKEVCGNNPIRDMQFSISGDQFLVTSGASEAKILTREGNEVTHTVKGDPYLRDARNTKGHTSALTSGRWHPSDKNVFVTSSIDSTLRIWDINRCKAGQTYVISVKSKLPGTRSPITCTTYTADGKVLLACAQDGAIHAWSSNGPFIRPSIDIDNAHCQGSGASGVAFAFNNINFTTRGLDDTVKLWDLRNTKNPIASTPPNLPNFFEETNIMFSPNEELILTGVSVKKNDPSHGKIVLLNSLNLEVIKEVKISLSASVIKVLWHPRINQIVTGISNGSCHVLYDPLVSVRGATICAAKKAKMAEFDHIDLQTNGVIVNPNALPMFRTDGNNQKSKKRQREDKNKFKPEMPLSVKGKRGELNTKAVDFIMKTREVDSTRLEDPREAILKHADDADEDPYWVAPAYDKNQPKPVFSQSVFETEEEERQESLKKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9W9</accession>
    <name>A0AAD5U9W9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">A1-alpha2 repression</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AAR2</name>
        <name evidence="2" type="ORF">HK099_006583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9W9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13777">
        <property type="entry name" value="Aar2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007946">
        <property type="entry name" value="AAR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033647">
        <property type="entry name" value="Aar2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038516">
        <property type="entry name" value="AAR2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689">
        <property type="entry name" value="A1 CISTRON SPLICING FACTOR AAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689:SF4">
        <property type="entry name" value="PROTEIN AAR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20981">
        <property type="entry name" value="AAR2_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAR2 N-terminal" evidence="1">
        <location>
            <begin position="27"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="278" mass="32551" checksum="D99207B05BA15CDF" modified="2024-05-29" version="1">MNEISVASQPSLKSVDNELLKKLFFYGGILLFANPPQITEFTIDFKTWQVGEKFKGLKFIPLGFHFISFQLIGSESTYLFWHFFNQNEVLVINWNTETEEFFKAQPEEIARYKYNIQEFDKFLGPYPLEESRSYEEFCALTSKLTAELLKNILPKSKDSDNKIVLNSFEVTSHLSKGNANVENNFLNFIHFDFKNFKKLKKHNLQSFRMQEHSDTDKIANISNSVNEKISSNLVGENLTNFYLDKSLLFENILMDFDKNRILGEYFILKWTSNAIFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB28</accession>
    <name>A0AAD5UB28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PAR-1</name>
        <name evidence="19" type="ORF">HK099_003511</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB28"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12121">
        <property type="entry name" value="MARK_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.80:FF:000011">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000156">
        <property type="entry name" value="Serine/threonine-protein kinase SIK3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF106">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="46"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="17">
        <location>
            <begin position="316"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="18">
        <location>
            <begin position="726"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="485"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3227058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="775" mass="86834" checksum="DE3B1C72C6F8C0DC" modified="2024-05-29" version="1">MASSVSPPCFNPSPIPPESCDKEKQKATPITTSPSYLQKVVKIGNYELNEVIGKGNFAVVKLATHVLTNEKVAVKIIDKSKLDKKTAKTIFREVKIMKLLNHPHIVKLYEVIDTPKEIYLIMEHVTGGEIFDYLVAHGKMKEREARKLFHQVVSAMEYCHNLRVIHRDLKAENILLDSNMNAKIADFGFSNQFTPGERLKTWCGSPAYAAPEIFQGIEYSGPEVDVWSLGVVLYVFVCGKLPFNGSSLAKIKVRVLSGKFEVPFSISLDCEKLINKMLNLDPTKRITLAEVMEDKWYIGEGTLERNKNNNLKLTITPDQRENILLELVQAGLNRDDIIRSVEENIYDPLSAAYYLVADKNFRKQQTETCTSNLIDIPAPERDVALSNLPNKLESKINIEITTNHLTSQTKPSNVVLFPQIKKIIQGQEIFNSKQNAMIQETSINTNLEKKTETSQRAATSTSGRRRAVTISNGYTTTEIRASVQTKTSMTESEQQKPQVIKPAAEQDQETSAILRVSKFPNSASGRRPLSFVDYPSTPVTEATDSSITNPCESNAKSNNVVAESEFKLKPRRLLSSAKNRPLSFTGVPTTMQIPPIPLKTDTKVISEVAPIAKNSFNIGGLFDNSISKAAVVPDNVQKRRRSKTFSAIITGNETKAIISPQTSEMSNIVTSPSSSLFSKKYEPRSIRFTFSEFTTSSKTPVMILENLSKVLTEIGVKFEIHLFTTKCRFDDKVEFEIEICKLPRLSLNGLRFTRLKGDSWVYKDLMTDILKKVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBK4</accession>
    <name>A0AAD5UBK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002893</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044444">
        <property type="entry name" value="Ribosomal_mL44_DSRM_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207:SF32">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="RIBONUCLEASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22892">
        <property type="entry name" value="DSRM_MRPL44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNase III" evidence="8">
        <location>
            <begin position="53"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3228388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="312" mass="35269" checksum="925D07C4786ACEEF" modified="2024-05-29" version="1">MLLQLTKSYSTKLQHFIKLNVKLNSSTSATSQNSKNIHGDLSQNLTPSEIATFSAFAHRSGLKFKNTSTLISALTHSSFKNDNSINHQRLQYLGHNTLKLFATEFVYFKYPNMPSEVVDSVTKGYIGRKALASVGEQFGIQNVMRWKFLQIDNNDPTHVNAKPYVISKVTEALIGALYQEEGAQAARRFIHSHFLNRSVDVRDHLLYLTRDPRLLLLKVTTKLGKRRPVARLLKESGRESNYSAYVVGLFIEAEKISEGYGESIHKAEIKATRAALEMHYLETLKEIELPSNLITENTTFFDADDIKEVGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBR3</accession>
    <name>A0AAD5UBR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="204" mass="23903" checksum="A1FC120CEFE3C43F" modified="2024-05-29" version="1">MSLLVFRSLWGIIDENNANDWDTTLKSLKEKGFDGVRDIGGDHETFQKAMKKYDMKLILGIYSSWQDYSDNGWKNVSVEGHLIEWKRQLDLAATLNTFHINSHSGQDTFTLEESKNFFKNALQYKNEKYPQLSLSHETHRSRILYSPWQTLELLNCFPDLDDPVYAREVQVFNDFWKLCLLEMNTAGYNLTLTPEYGKLLFKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBR9</accession>
    <name>A0AAD5UBR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="299" mass="34221" checksum="343ADFA54965FC10" modified="2024-05-29" version="1">MGLACSLQGWENQFLYFSENEKSEEYQVCCFDNRGAGLSDTVLGRYTTSILAQDAAELLDHLKWVKDIHLVGISMGGMISLELALLKPTVFSSLCLTSTHSGTINHPISYRYPVFFSRQLKMLNPSHPFISAVHMLFPEKFLAREAPKEFQPVHIPFKDNYTMEDVVIDGIRRKDRKTRLTTAAGFIGQISAVMTHYVSPARLRMIKENPNVLMVEKLGGRLDLYHDHGHALPEENPKRYNKMLEEFINESILKKEALITLSKKMEDILIKECKDNDNGFIQLNDKRVVHSKRDSKFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC03</accession>
    <name>A0AAD5UC03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transmembrane protein 63C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TMEM63C</name>
        <name evidence="12" type="ORF">HK099_000047</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC03"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF139">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="435"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="590"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="661"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="698"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="19"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="215"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="387"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="872"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="879"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="895"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="931"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="968"/>
            <end position="1023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3228492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1023" mass="117634" checksum="D6FBA27067EF918E" modified="2024-05-29" version="1">MSDTSANTQLKTNTDLQGLGTAFGIQVLISFGVILVFSLILRPYHRVIYEPRSKFAPDSKKPLPLTKEPLSWIQTTRKVDILLAVDKIGLDAVMYLRFIKFCVHFFLCATVFAVPLCLFHYFIMPAPPKPTTRRSKAKVSYSLELLTISNIHFKVEEFGGDTDPNFYYWFYMYSSLLWMASLWCYYNLYVIWRQFTHLRRHWFKTAEFNNGHHNKTLLLSGVPDELKSEEKLQRHYEKLFEKESYGNFQLIVGRDSKKLTTLVTEHLKCTEKMEKTLIKFLKSSKGKRPTHSEDGQKVDSINFYSKKLNELEEQIYDLRVNGDKKLEQDSSAFISFDTILSCHKVAKKLEHPLNIGGVLDPSVKLCPNYDDVIWKNVGLSKSALRGRRFLTIAIFIAIALGWTGLVSFVTVLTQLDTIKTFSPQLALLINENKFFTIFFTSILGPLLLASLNLLLPIILRYLTVFQGVKTNEGVEKSVLRKYYFFLLYQFLLTTGVTTLLVTYFSSLNLNPQTGEQIVEKTNADGTTTTNGVFNTLLTPIASGFLKFSTTFIILASQSLTGYSIEIAQAVPLLSNMIKRRFFNLTPRQDYIWFTTVSICLFRLLFYRRSIYSTIRIIRCVYFMLEIYLSDKNIAAFSFTYSIMKYQILYVYETRVETGGTWWPKVSTLILIGLFLCQFTTAGVLSMKIWIENSGRSRGPVIMATIAPAATLLFWFYINRTFAVNTKFVSEDLSSYAAAFQKETENFNLEEEVFNPAFAKPLPKIWLPSSLENKVEQFHKLEYSSLEDYLKKKNPYMFDNQRNNANDSSSTLGSAFDVAKAHRLAAQAQRNDDFVRRETMKRMSALGNPIQLGGELRGYEADSLKYRQQYSSDNFGFSDYEGRPLMVEDRPESPHYMQSTGNMYPQPNNQEIGSQNVGHPQELSQSQMRYGQTQYTNQPQNPQPYYQNSRPSPQQQFQPHQSSALHYQRQPQLAGSVISTASHRSANSSHNPAGYQQSSQHHQRNFPQQRYPQSNHVKNNYNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSX0</accession>
    <name>A0AAD5XSX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000272</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001056">
        <property type="protein sequence ID" value="KAJ3207402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSX0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056155">
        <property type="entry name" value="Beta-prop_IFT140_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056168">
        <property type="entry name" value="TPR_IF140/IFT172/WDR19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056156">
        <property type="entry name" value="TPR_IF140_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722">
        <property type="entry name" value="IFT140/172-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722:SF7">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23385">
        <property type="entry name" value="Beta-prop_IFT140_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24762">
        <property type="entry name" value="TPR_IF140-IFT172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24760">
        <property type="entry name" value="TPR_IF140_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT140 second beta-propeller" evidence="6">
        <location>
            <begin position="31"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="IF140/IFT172/WDR19 TPR" evidence="8">
        <location>
            <begin position="329"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="IF140 C-terminal TPR" evidence="7">
        <location>
            <begin position="547"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3207402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="713" mass="80464" checksum="26240FA42E4BFA0F" modified="2024-05-29" version="1">MNDQVQPEGQTKMLLYDIESDKVIPVDFGSTHHVTPVTQHWDTTDGRVFVTEVEGFISRPSADPDMTEICTPFKEVFTMFATSDNGIHIQDRKLINDASDSLIGSSMPFHFYLKKVVSKDSKQGEELIIEKKATKDFEGMEDADQNTIKATLDFSFYLSLGNMDEAFKCIHSIKNKAVWEHLAKMCVKTKRLDVAMMCLSNIGSSHTIRALREAAKEPEPEVQIGILAAYLGLLPDAENILSSCNRYDILNKLYQASGQWEKSLELSGTKDRINLRTAYHKFGKYLGEIGDVNGALAAFEKSAAYSFEVPRMLLLQSGELEKYINTSPDKAIELAQKTKNSAAAYHIARQYENDKKINEAIAFYSSAKCFNHAIRLAKEYKMENELIHLALQGSKESMLEVARYYETTPKNHDKAIHLFFKAGSVARAIDLCFQTNQFGILGDLCSELGKDIDPKLLRKCAAFFYEHGQFDKSVSLLVKAGDNAEALDICIQKNVTITEELANDMSVTSETQELVAKGILIRIADCCLQQRSFLVASKKYTQAKALDSLATFYEACAQVEIDEYQDYEKGLSALTEAAKCLSKAKNVSEAEIRLRTLQHKMDLIKQFVEARNIVKLDPSSPKWVAICEKLLAEPDIDESGVKSGDIYAMMIETHYSATFYEPAFNLLQRMKEKVSSANIEYFLDNRIVQALDKNERKLMEVNDDIREDIREEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV52</accession>
    <name>A0AAD5XV52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DBP3</name>
        <name evidence="18" type="ORF">HK099_005178</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000393">
        <property type="protein sequence ID" value="KAJ3218164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV52"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="374"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="405"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="631"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="211"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="374"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3218164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="815" mass="91443" checksum="4A2C419B547E31B0" modified="2024-05-29" version="1">MFNSMTSLFGKAQASKTQPKDAIVKLRENIEMLDKREKYLETKVIAEISIARANATKNKKVALMALKRKKLYEDQINKNQGSRLMLEQQVMVIENANVNKETMEAMRIGAEGLKNIHGAMDINKVDEIKDSIGEQMDLANEISEAISQPIIFGQEIDEDELDAELELLQQEEADEKYLAADGMHHAPSVPTNVIPAIAQPPRPIRVQQSVEDEEDAELAELKASMALARTETEEENVSNLKNGDESLKKIEKKLKKEEKKKRKLLQEETVTSNIDTNALKSHKKSKKSKKEKVEEDKVDKSEVDTVKNKTTVKDRTLAENLKRKEKTISDNCDEWNYVENPSLTTLSQAEVDSYLKKHTIELIDEHQSPKRPVMSFNLINFPSEIQKIFDKLKFENPTPIQAASWPSVLSGRDLVGIAATGSGKTFAFGIPALIKILNKKIKQKVKNQKAVIKAAPIVLILSPTRELAIQIQQTLENFTEVLKINSVCIYGGVPKWEQKKLLLENGGADVVVATPGRLLDLLGFSFGSDELSGNEISMDVQNVEMFILDEADRMLDMGFEKDIKRIANGITNKNKQTVMFSATWPKEIQSLALTYMKSPLRITIGTTNLLTANTSITQHVTVLDPMAKEKKLLELLNLYHSSRKNRVLIFVLYKKEAVRVEQFLKRNRWNNVKSIHGDLNQQQRLNGLESFRDGTTPLLIATDVAARGLDIPNVEYVINYTYPLTTEEYCHRIGRTGRAGKSGISHTLFTLHDKSHSGALINVLKGAGQVVPDSLFAFGTTVKKKLDPNYGAFAKDVDMTKKGTKVVFGNDSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV65</accession>
    <name>A0AAD5XV65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein kinase C</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PKC1_2</name>
        <name evidence="18" type="ORF">HK099_005080</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000381">
        <property type="protein sequence ID" value="KAJ3218427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV65"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05570">
        <property type="entry name" value="STKc_PKC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000210">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000103">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="16">
        <location>
            <begin position="485"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="642"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="17">
        <location>
            <begin position="902"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="671"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3218427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="979" mass="111593" checksum="4A6FFFBFBF880A7E" modified="2024-05-29" version="1">MDTDIFVKNQQNHEPKEIYQIKTGKSKYGINDINNQFCNIELDTKSFSLSMDGFFQSTKETKTNVSNTENNAIRLKNKEPIFSTSAITPSETQLPNLLKENNSKNHLRGNTVSRSTVVETVLTTLGRKKDTFTGGKATTSNQSPSKIATNQNNVNRIPLTQFGRVLFISFHCLTLRQDYLLNDVPLSIEKIKYKLGGIGYKLDVEQKVYSGTERMHQALIKNATSVDQKRMAEIDSKMKECARKVLILQKAECKYKSIIPEGVDIGNDEYFGSNYYTNHTTLSLHRQTEFRDNASDAINGVPKIRQLRQPLSGKFYIKVGKMFGISETKAVRSETSVLIKIDGNEKGTTRVLKSFQKWNEEFIITVEKSSEIEVSILEKGGNILGSVWFKLWELEEALRARRKAFFPIHQTAIENAENKENFKDKVLEGIFDLEPAGTIELCLNFVNQTNIKRKEGVARRKNVQKVFPMDDSEGDSIAQMRHRIPHKFEPTNNLLSSWCCHCGSMLSFSKKQSLRCSECSIMSHKSCAHLVPNFCGLNPMLISQMLKAIETVRSKKSETKKVENFVTKESPKKDSYNKRKSIVEDITTAFSFDSIGQSTKISNHQSINQQLVSNNQSSNKASNLGTKVVAKNVPRNVGLNDFNFLAVLGKGNFGKVMLAEEKWSKKMYAIKVLKKEFIIDNGEVDSTRSEKRVFLAATRERHPFMINLHSCFQTESRIYFVMEYVAGGDLMWHIQRQYFTEQQAKFYACEVLLALTYFHKQNIIYRDLKLDNILLTIDGHIKLTDFGLCKENMKFDSRTSTFCGTPEFMAPEILEEKPYGRAVDWWAFGVLIYEMVLGQSPFKGEDEEDIFEAILHDEILYPVNMTRDTVGLLQQLLMKSPDLRLGSGPGDGEDIKVHPYFRGIVWEDVINLRIPATYLPKVSSPTDVSNFDSEFTKEPPVLTPCRKILSAVDQDEFKGFTHVSEWATMERINLLTQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV70</accession>
    <name>A0AAD5XV70_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">small monomeric GTPase</fullName>
            <ecNumber evidence="1">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAP1_1</name>
        <name evidence="6" type="ORF">HK099_005042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000379">
        <property type="protein sequence ID" value="KAJ3218469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV70"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032486">
        <property type="term" value="P:Rap protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04175">
        <property type="entry name" value="Rap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000182">
        <property type="entry name" value="ras-related protein Rap-1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038851">
        <property type="entry name" value="Rap1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="183" mass="20875" checksum="81C548E50CBD7D71" modified="2024-05-29" version="1">MREYKLVVLGSGGVGKSALTVQFVQSIFVEKYDPTIEDSYRKQVDVDGLQSMLEILDTAGTEQFTAMRDLYMKNGQGFVLAYSITSQATFNDLVELREQILRVKDMDKVPMVLAANKCDLEEDRVVTKEQGQALSQQWGCTFLETSARKKINVDEVFFDLVRQINKSMPEKEKKKDKKKCLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVC6</accession>
    <name>A0AAD5XVC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">V-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000759</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001191">
        <property type="protein sequence ID" value="KAJ3205602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVC6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000004">
        <property type="entry name" value="Vesicle-associated membrane protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016444">
        <property type="entry name" value="Synaptobrevin/VAMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45701">
        <property type="entry name" value="SYNAPTOBREVIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005409">
        <property type="entry name" value="Synaptobrevin_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3205602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="105" mass="11688" checksum="CE1278A2426A5BE0" modified="2024-05-29" version="1">MSSSKGKNFQQSNGGVHKAGQVQEQVDEVIGIMHKNIEKVMERGEKLDSLQTKTDDLQQGALQFKKGATKVRKQMWWKDLKLKLVIAGIILVIIAVIVTVAMAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVD5</accession>
    <name>A0AAD5XVD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BRCA1 BRCA2-containing complex, subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BRCC3</name>
        <name evidence="2" type="ORF">HK099_000701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001176">
        <property type="protein sequence ID" value="KAJ3205779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVD5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041933470" evidence="1">
        <location>
            <begin position="20"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="295" mass="33995" checksum="6404C37E255FD923" modified="2024-05-29" version="1">MKVLSSVFITSNAFNLILAHSLTTDNEEVCSLLLGFFKTQQHSINAFVTNIQFVVRRDKRRDRVEIEPEQLSLAIENAESKGLKVIGCHVDVGTQNSLQQLDLNFFGLILSCFDKNVNRLQLTCFQAQKDANEHVKSLEIPVFILPSLNKHDLIDHFDGCDLPDQQDTFTELGERLVSVLMEEEKLNFEKFVNKNDNQELINIEKLNENTNNYLETSYHSLLYLMSLTNILDKICLPIEHLFKERLERNLREIKELEECDSISKAKKNKDSVDLISFEDDDEVEVIPQSPNLFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVS2</accession>
    <name>A0AAD5XVS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isocitrate lyase</fullName>
            <ecNumber evidence="5">4.1.3.1</ecNumber>
            <ecNumber evidence="4">4.1.3.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Methylisocitrate lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Threo-D(S)-isocitrate glyoxylate-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ICL1_2</name>
        <name evidence="14" type="ORF">HK099_001900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.1" evidence="5"/>
    <dbReference type="EC" id="4.1.3.30" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010001592">
        <property type="protein sequence ID" value="KAJ3202294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVS2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.850:FF:000001">
        <property type="entry name" value="Isocitrate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF3">
        <property type="entry name" value="BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="9 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3202294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="351" mass="39145" checksum="C7537E62078B714C" modified="2024-05-29" version="1">MFVERGAAGVHLEDQSPGTKKCGHMAGKVLVPIQEHINRLVAVRLQFDIMGVENVIVARTDAEAADLLTSNIDKRDHPFIVGSTNPDQEALVNVMEDARAAGKTGAALQQVEEDWKKAANLKLYSDAVLDVLKADKSKAKHVDDWKKKIDTLSHSEARKLAKSYGVDIFWCWDLPRTREGYYRYRGGTKCCIARAVAYSPYCDLLWMETKKPIFDQAKEFQEGVHKKCPGKMLSYNLSPSFNWDAAGMSDKEIGGFCDKLGSLGFVWQFITLAGFHSNALITDMFAKDFSKRGMLAYVEGIQRKEREHGVETLTHQKWSGADYYDNLMKTVQGGVSSTAALGKGATEDQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVY9</accession>
    <name>A0AAD5XVY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003899</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000262">
        <property type="protein sequence ID" value="KAJ3220940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVY9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="204" mass="22704" checksum="3619D76FBCBEAB6D" modified="2024-05-29" version="1">MNSWSLPAEVLISNKLSLSENSKSASKHKDILPGDGLNAIWGHGKQEESRTNCEMCLSIFSNQLGNNNIDGNPSLEGLYANFRVTSWGTIYPFNTWEDKIYRDVARGMVIEQLKYHNANRPIIIVGTWKLCKSAIVTVFFLMPAIATSSWSIPSMTDDTIEHARGYLNVESASSNMKDNICITKSYGPTKIAGRIKSCISCLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWR9</accession>
    <name>A0AAD5XWR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000182">
        <property type="protein sequence ID" value="KAJ3222288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="168" mass="19135" checksum="A0165644DD27EE93" modified="2024-05-29" version="1">MNGFSFNNISLFGSKKRRSTNGIDSLLKKSFNSSSSLSSFDKKLIRQREEEEILENELNFKIASLIQDLGYNTSFTTVAPSQIQKSKSNLSVSTEASTSCDLMVQRELSHNQSIPVENLYRTEFSDENIFKQKLAFVYTGFDERIGYIIVALKENKNNLICYVMTKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWV8</accession>
    <name>A0AAD5XWV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U3 small nucleolar RNA-associated protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_006623</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the NRAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000585">
        <property type="protein sequence ID" value="KAJ3214881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWV8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005554">
        <property type="entry name" value="NOL6/Upt22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035082">
        <property type="entry name" value="Nrap_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035367">
        <property type="entry name" value="Nrap_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035368">
        <property type="entry name" value="Nrap_D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035369">
        <property type="entry name" value="Nrap_D4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035370">
        <property type="entry name" value="Nrap_D5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035371">
        <property type="entry name" value="Nrap_D6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17972:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17972">
        <property type="entry name" value="NUCLEOLAR RNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03813">
        <property type="entry name" value="Nrap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17403">
        <property type="entry name" value="Nrap_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17404">
        <property type="entry name" value="Nrap_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17405">
        <property type="entry name" value="Nrap_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17406">
        <property type="entry name" value="Nrap_D5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17407">
        <property type="entry name" value="Nrap_D6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Nrap protein" evidence="7">
        <location>
            <begin position="187"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="8">
        <location>
            <begin position="340"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="9">
        <location>
            <begin position="493"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="10">
        <location>
            <begin position="676"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="11">
        <location>
            <begin position="883"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="domain" description="Nrap protein" evidence="12">
        <location>
            <begin position="1054"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3214881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1211" mass="139114" checksum="8C3BFF0C020758D8" modified="2024-05-29" version="1">MKRTANKKELKSSKKHKSIKDDTKLESTEKEIALDEEVDVFSDEDFIEQPNFENERQTVVGDSKFRPPTAEEMLMLKDTMQLYKSSLFRFQIEELLKEVQFDFPKMIESTLHEVKSTLDSIESVSECSLADIISSLGVSDIKIPFPEPKPSTHNQLKFSFIKPSKIFIVGGYLLKSNVKSKNEEKNIDVAIQMPENLFQEKDYLNHRYFYKRSVYLAVVAREFNKNSNKLSLKAEFQYFNGDELRPILILRGSKDNSLKDISKTNTIIRILPLLPENVFNLKKLSPNKSCIRYTENDTLNNKEENNNRCSTPRYNTSILQDMGFVSHLNYLHVNQKKCQAFRETVILAKVWLKQRGYGTNGDFNSFIFSMCMAWLLNSGPNGAERRLMSTYSSFQLFKLTMEFLGNHDFEASPLFLTKNGCPISDTDFSKANFSLYDVAIVDPSGRINLAGHLSTSQILEFQESAKQTVRFLNDKNDDKFDLIFLKKVNVLHLEFDQLIKIDTETCKPPAFIPPYSLDYSSSTQFTASLIPKKLTAGLGTRLLQCSVRNSIHKKSWALDATPKMHSTFYVGLKIDQENSLRGVEYGPSAEKIKDVKAFKELWESKSELRRFKDGSIIESVVFENDGTFEGRSMTVSKMAIHLITLHCGIAARDIIIWSGAQFFPFLSLPGKSDVLLPNKSFKSVMDVFNSFQKKLKNYTTLPLNISTVQPCSPGLRYTSIFYPQPDNGNQMEIVKLDEALEVNLEFESSARWPDDFDAIQEMKLAFYLHLGKTITDDWEGSKATVSVNDRTQFNNTIQFIGRSILTERFLDVKSPEGYTFRCRIKYEREELLLEQLINPLPSIKQASTFGIATAKQTLQIYKHLFKLTPYYSYQIQQFCLRNPCLSFTIRLFKRWLSSHLFLNCQIPEIVPELLCCRAFMEDNVWSKPSSVFSGFIRVLHLITNFDWENVPCILEFEDFDNNSGINVDTIVEGFKGIRSNSSEKGGIGGGFFFIASMADPKCSIWEKGMGNNFDIVSRLITISKACLKHVNSWFENAEASDFAKMFLPATNFIDIKVNLNKSLIPKYYENFFYKKTFAPKKKITFKNLSNSTEGKLDKMEYLKYVDPVEVFFDEIRTANFIGDESKIFSMFYDFCGGDYFGLKLNKKFRNEVQEERKDFDFKVNLGFSSIPAAKKEMKGNKILPKVYLNFEGILAEIKKLGDDLVEGFEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWY7</accession>
    <name>A0AAD5XWY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Outer dynein arm-docking complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tetratricopeptide repeat protein 25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TTC25_2</name>
        <name evidence="10" type="ORF">HK099_006459</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000559">
        <property type="protein sequence ID" value="KAJ3215201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWY7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040111">
        <property type="entry name" value="ODAD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040:SF1">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="340" mass="38510" checksum="1D2DEA055B73D367" modified="2024-05-29" version="1">MADASDGEVILSPEEIMATFVSLAAEGDLYGQRGFFVEAIESYTRALSLRPEDKNCLVSRSRCHLQVGDADLSLLDAEESLKEDPSYFKGQFQKAEALYAMGDFEMALMFYHRGNKLRPELEEFRIGIQKCREAIENSIGDPKTCKISISPKLKKEVLQLFSNPLRKEKGKANDKSSKIGGYLASTPTNVVPQTPVVSTVNPNNPNSVNAFLIHRGITPPATSTLTPAMESKLLGDLYDDKAYLSKLLSDRDLIEHPNDHVLRLVAEGLNYFNTRIDFWRQQNPLYARQTHQLKYYKPLKTKHHEDDVLINKKKIKRVVDEHNKKNRVHLPPIDQKKVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX16</accession>
    <name>A0AAD5XX16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000157">
        <property type="protein sequence ID" value="KAJ3222824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX16"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF1">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="165" mass="19349" checksum="CF11F1FB993A66A4" modified="2024-05-29" version="1">MGKKDINKYKRFSGAAVTLALQQYELLGCWNKVAALDAYKRFNLTGQQMCEKVYASKTTKKQTGVKITIALDTPYEKIESLKDYLVHYLENEESREFFSDLSYKINDFVSKQALVLNFWITHKSNWQDVGRKNARRNRFMCKLREGLIALGIELTDFRMELQERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX39</accession>
    <name>A0AAD5XX39_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="3 12">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ALG11</name>
        <name evidence="15" type="ORF">HK099_001490</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="3 12"/>
    <dbReference type="EMBL" id="JADGJW010000142">
        <property type="protein sequence ID" value="KAJ3223143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX39"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="38"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="270"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3223143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="468" mass="53776" checksum="D77906E7F8B4A222" modified="2024-05-29" version="1">MHTFTIVIIAFALLSSLFRILKNKLKLKQRIRHNIGNKVIAFFHPFCDGGGGGERVLWTAIHAIQHKKELSHYTILIYSSDIPKSKKELLAKVKDQFNIVIFEQGLEVVQLKMWKWLEAKRYPRFTLIAQSLGSIIVGLEALWIFIPDIYIDTIGHSFIYPVVNFFFDCVVVAYIHYPTISTDMLKNVKYGMANFNNDKRIAGSAILSNAKLIYYNFFAVLYGFAGYFTNLVMVNSTWTQNHIKHIWRFNFNEPKIVYPPCDTTSMLKIKLNDFKRKLIILSIAQFRPEKNHLLQVKSFKMFLDLNPKFEGKVELILVGSCRNQEDRKRIDDLKTVIMELNLSNAVKIVENAPYSVLFDYLESATIGIHTMTDEHFGIGIIEYMASGVIPLAHDSGGPKSDIVVDYKGEKTGYLACTVEEYASGIKTILELSYRERSKIQLNARNLITEKFSEENFSKMFIDNLSKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX71</accession>
    <name>A0AAD5XX71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_006077</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000500">
        <property type="protein sequence ID" value="KAJ3216059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX71"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07817">
        <property type="entry name" value="GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="129"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3216059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="498" mass="58155" checksum="D0034C8AC2C9930F" modified="2024-05-29" version="1">MGRYSFNTTESEVRTPTQIENLAEIEEFTSNVKLLTIKSPQKLKKFNVDVVNEEKKKKKNKIKPNTFDIGTEKQHSPEFKSALEKKNKILEQDLKLQTQKTLNFLKNLKDRQNNVNSKFEESLKLCLEIENNEKLKVQEKERIQQEEKQKKVLKEKQQQEADRLEKLNKEKLEQEKILHKKMENEKKIQFEKLQAEKLQNDKILALKDEDLNYCSVKANEESTKYLQKILKIKKILKPKLRQNPRFKKVFFDQKREINTRIGQVKNSLKKIQEIISVIDQAFQTAARESPELLEWLMDFTAKALTKQAESEVAVNKPVAKFLGMVAVGIFQKYPNFLEILLGRMMKSCPYIIPRYFKRLPNESGEDFKKRHGYGENEKEDLYVVRMNGVLAFYCGIFVSDGNNIHGIEYSWVWLARLLNMKPRKITASLIQTFLEIAGSRFLEVFQTQGRKLINFIIKDYCILFPSSAIASGSRLKTFLENGYLNDGSLPSILPDLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX96</accession>
    <name>A0AAD5XX96_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2-hydroxyacyl-CoA lyase</fullName>
            <ecNumber evidence="9">4.1.2.63</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">HACL1</name>
        <name evidence="15" type="ORF">HK099_007872</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 2-hydroxy-3-methyl fatty acyl-CoA = a 2-methyl-branched fatty aldehyde + formyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:25375"/>
            <dbReference type="ChEBI" id="CHEBI:49188"/>
            <dbReference type="ChEBI" id="CHEBI:57376"/>
            <dbReference type="ChEBI" id="CHEBI:58783"/>
            <dbReference type="EC" id="4.1.2.63"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:25376"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an (R)-2-hydroxy-long-chain-fatty acyl-CoA = a long-chain fatty aldehyde + formyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:67444"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:57376"/>
            <dbReference type="ChEBI" id="CHEBI:170012"/>
            <dbReference type="EC" id="4.1.2.63"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:67445"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.63" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000801">
        <property type="protein sequence ID" value="KAJ3211997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX96"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106359">
        <property type="term" value="F:2-hydroxyacyl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001561">
        <property type="term" value="P:fatty acid alpha-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02004">
        <property type="entry name" value="TPP_BZL_OCoD_HPCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000006">
        <property type="entry name" value="2-hydroxyacyl-CoA lyase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000038">
        <property type="entry name" value="2-hydroxyacyl-CoA lyase 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045025">
        <property type="entry name" value="HACL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026947">
        <property type="entry name" value="UBN_middle_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43710">
        <property type="entry name" value="2-HYDROXYACYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43710:SF2">
        <property type="entry name" value="2-HYDROXYACYL-COA LYASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14075">
        <property type="entry name" value="UBN_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="13">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="11">
        <location>
            <begin position="190"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="12">
        <location>
            <begin position="389"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Ubinuclein middle" evidence="14">
        <location>
            <begin position="862"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="576"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="666"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="592"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="666"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="694"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="727"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1086"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3211997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1086" mass="122229" checksum="B7DAC49C3CADF443" modified="2024-05-29" version="1" fragment="single">MDGATVLAKSLKQQGVKYVFGIVGIPVIEVAEACIAVGMQYYGMRNEQAASYAASAIGYLSQTPGVCLVVSGPGLIHALAGMSNAQVNNWPLIVIGGSSEIRQENMGAFQEFPQVDASRLYCKYTVRPGSIPQIPNIVEKAMRTVTYGRPGVAYIDMPADFVTAKVPENLITFPPELLPPPQSLADPQQISKAVDEILKAKTPLFIIGKGCQYSRSEKEICNLIEYLGIPFLPTPMGKGLMDDDHKLCVSAARSTALKSADVVVLFGARLNWMLHFGLPPRFKPDVKIIQIDIAPEEFGNNILGDRAIHLLGHLPQVITQIYKEISKRNPSPVRKEWWSVLNKKVAANKAANLLLMKEEELPMSYYRAFAEIKPLLPRNVFLVSEGANTMDIGRTILDQHLPRSRLDAGTFGTMGVGLGFAIAAQVYEPDRVVCCIEGDSAFGFSGMELETACRAKLPILFIIINNNAYKNWDGPRPSTSLLPNAHYEVMAQAFGGEGYFCENPKQIKDAIINFLEKRKKGVAKTTVLNIMIRLLKYLWMSSLRIEVDVDFTNENGNVIDYAKLLKEHLKATEVSEEILTKNSTPGTNEEKLEIEEDLNEEEERSSSEDEKDEEEKESEVEKKEEEVVKKKKRTRNNKETEYDYDDDFIDDSELFFVEGKPLTDYEKEEVEREAEEEEGLGFFCWKGSLDDVDPFEKTADQEKKKGGRKSNIANNTTESKQSRRTKNFATDNSGGNENTTPTKRNKKKESVLLTENSTSNNLNSDSSGNVFISPVKPKTAKKKSSLAKDDKLVKTEELIEKNKKDGLLTVNTSNLPIKRKLNESERHSIIQKKKKIDEFEETVNTPANVAEISKKVGSAVIQPLPFELQMDIEFLKHKADEHSWENKKHFPESLRPAILQIAKNAEKLNLLDDNLYHHVTKAIPYNILTVRKLLQRSILQHEIIKVNNNIKSLSAELKINLDKELPSQEVAFSALKPSSVLVLGEKGQSVTKLEDPKRKFKWNTTIRSLFFDFVNCEFEKVELENKFHTLKEKFNLVKNEKAARSYIFNLVAGFWPEGWVTSSELSRTFSNMKSNLKRKEKPNLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXA5</accession>
    <name>A0AAD5XXA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">26S proteasome non-ATPase regulatory subunit 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PSMD14</name>
        <name evidence="9" type="ORF">HK099_001271</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000134">
        <property type="protein sequence ID" value="KAJ3223349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXA5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="8">
        <location>
            <begin position="32"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="310" mass="34458" checksum="EB0CF9D549DD15E1" modified="2024-05-29" version="1">MDNIQRLFGSLGGQLPQQAQIDTPTVDTAEMVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQTKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSSVDVNTQQSFEALNQRAVAVVVDPIQSVKGKVVIDAFRLINAQQAMMGVEARQTTSNIGHLNKPSIQALIHGLNRHYYSIAINYRKNELEQKMLLNLHKKTWSNGLVLDDFIEHSVDNEKAVKTMLGLAEAYNKSVLEESVMTADQLKTRHVGKQDPKRHLEDNIEKSMTANIVLCLGSMLDAVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYG5</accession>
    <name>A0AAD5XYG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000506">
        <property type="protein sequence ID" value="KAJ3215983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYG5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="3">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="16448" checksum="A28E0383598BB92E" modified="2024-05-29" version="1" fragment="single">SCVNTIKKSLSTLTGIEEIDIKLNEGFATIKHDIFLVSVQDLITNIEDCGFEATLNTEGNNTIPFAASPVVAPFKPSKKNTPEDSSSFQAAVENFLSASSIKSNNATLLDTESFPLTNMLRINENASITNIRVQVLLFLIYILTILTLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYG8</accession>
    <name>A0AAD5XYG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000276">
        <property type="protein sequence ID" value="KAJ3220750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYG8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="178"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="233" mass="26415" checksum="89FFC9048444B9D0" modified="2024-05-29" version="1">MNNCFNSYISNECSVTEIQAAASFSLISPLHQSIPFDGNFHSTLHDTVNSFLSQFSPYASHYSLASPTFEESVEQELNDILFSSSILHPSNSASHLYESESETQLSSVSSLNLSSNSIIMNNYELKPITDDKSNQISDLSFHIKNKSPNPKVKSRKSMNVKKKKFNNPLNQEKITQFFPCSQPGCKKVFTRKYNLRTHESVHLGLNPKFPCNECTSIFTRKNDLLRHSRKLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYS1</accession>
    <name>A0AAD5XYS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome 5 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000456">
        <property type="protein sequence ID" value="KAJ3216873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1148"/>
            <end position="1164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1319" mass="144814" checksum="0DDF7E483A785161" modified="2024-05-29" version="1">MVLTAHYSHPLEAFVLNAMSLLLGPIILRSHLFTSWIWFSYSLINAINTHSGYDMPWNRGSNLFCDFHFENFHYNFGILGFLDSFHRTDTAFKQRYPSITLLPNGAEITREINAEFEKDEEDGVNWVLNDENNVNSREIKIESKKISVESSVSDSVDDTESTINSQVIASVETANNIQTNGGLDVNEIISEQVLDSLNSEIVVDSKSINNEVDTSIKTLTVEDSDTQVSMTTMSVGKEPKEHIQTKSTLNETIQEEKVDDVSQFEEFSIQATEVVDLTKPAETIETIQYNIKLSNAELENVQITEEVELSSIAEESSSLQAIAEEAETPESIKVESIQSEAVQGKLDADSQSVGTIEKETSATASEVKIEIVETTLVEVETVQATKMEVEFTNSTPVEADTVNSIQELGDEVTQKEPAAEIELTSSETVQVETTQSKAIQEEVVVAGEQAINSTEEVIITTSHEVKIETTESTEIEEVKPTETVVDENELTKLQLSQDNNSDVEVTSSETVNVEVTQAETEVEVTITTSHEVKIETCESVEIEEVKTTETVVDETESTNLQVSQDSNPDVEVTQVKDAVEKTSSETVHVEAETEVEVTFSETVQVETTQSEAIQEEVVVADAQAINLSEEVTITTSHEVKIETTESTEIEEVKPTETVVDENESTNLQLSQDNNSDVEVTSSETVNVEVTQAETEVEVTSSETVHVEAEIEVEVTSSETVQVETTQSEAVQEEVVVAGEQAINSTEEVTITTSHEVKIETTESTEIEEVKTTETVVDENESTNLQLSQDNYSDVEVTQSETALEATSSETVHVEVTQAETEVEVTSSGACNVEVTQTENEIEVTSSETVQVETTQSEAVQEKVVVDGEQAVTSTEEVTITTSHVKIETSESTKIEEVKTTETAVNEIESIAVELSEFAETVSQIVESEASVADVVENSAEINLETVQSSEMEVQASEVNDTEGVSQVASETEENVAIQEAVAVELITNTTEVSEVRKEIVESIEVEIIESQTSSTVVEVTQNEESIQVIQEADDVDKAQMTDAGEDSSLSSSKVEITHTMQKVVGVTDESIVTDAAEFSELQLEKISESTKTAQVSSNNIETVNTEYDAHQSEQVVVADIKESVSQITIEETSVKQVLSEEKVDLDSTEVNESNYGNSDDQMDSTVNLDDVKKVVLTAQKSTNVETLEEQVDDNMGDGIPLATKILSVDVAVEEVSEVMHLKEEISSVITTIDTEEPQLKIENSELVKELSEKVEEVTKEENQLEESKFSVKLEEAMEGSAVGEIKVVETAKVIEKKTIKVMKQHPGGRFEIVDEIVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ26</accession>
    <name>A0AAD5XZ26_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ26"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF3">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="216"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="377" mass="43680" checksum="B361A53A7FF61979" modified="2024-05-29" version="1">MNFSSVENRVGIILKLSSLGKNLEFLTVYNLNLKELKNFDNNFSTTEEVFEIVFKKVDSNTTIGKVGDLINVELFPELDEKTSLQKVSRKGFKCFQLLNKIEENIYLGLDKSEFLLELDIVLWDLTLENSANLGMQLLKIMSLSFSNFNRHEFFTKSEELKVMEEINLKSKANKKKDFEMNTHEGDFHLCEKVEKTKSDKEFTKWIIKTFGKSYLQAGSGVIDIAGGKGHITFQLHCIENINCTLVEPREVILRSWQRKLIKKQNLVTFQHKKNFFNKEFCLESSNTEMLKNCSILIGMHPDQATDEIVDFALKNWKSFAVVPCCVFSNLFPNRRTSAGKHVRTYQEYIDYLLGKHADIKKDFLNSEGRNIIIYLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZD8</accession>
    <name>A0AAD5XZD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GTP-binding protein Rho1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RHO1_2</name>
        <name evidence="10" type="ORF">HK099_004775</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000349">
        <property type="protein sequence ID" value="KAJ3219177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZD8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01870">
        <property type="entry name" value="RhoA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000329">
        <property type="entry name" value="GTP-binding protein rhoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3219177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="195" mass="22093" checksum="85661850F0B52BB8" modified="2024-05-29" version="1">MNAEIRRKLVIVGDGACGKTCLLIVFSRNEFPEVYVPTVFENYVADVEVDGRHVELALWDTAGQEDYDRLRPLSYPDSHVILICYAVDSPDSLDNVQEKWISEVLHFCAGLPIILVALKKDLRNDQKTILELQKTRQQPVSYEQGKAVADRIGAYRYLECSARTREGVKEVFEHATRAALAVRPTKNKKKGCKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZE8</accession>
    <name>A0AAD5XZE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006056</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZE8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015086">
        <property type="term" value="F:cadmium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034755">
        <property type="term" value="P:iron ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01197">
        <property type="entry name" value="nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037982">
        <property type="entry name" value="Nramp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706:SF101">
        <property type="entry name" value="MANGANESE TRANSPORTER SMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3228176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="498" mass="54716" checksum="3A69456901212E31" modified="2024-05-29" version="1">MSNTLKHTKSFFKSFASFLGPGYMVAIGYLDPGNWATDLAAGAQFGNKLLFVILLSNVVAVLLQYLCVKLGIVTKNDLAQSCRKYLPNGVNIFFYILCELAIIACDLAEVIGTAIALNLIFGLPVTLGIILTGLDVMVILFGWNTKHFRRFEIVLFGCVALVFACFVVLIIKAQPEWLSVFKGFVPNRLVLDNRDALYIAMGILGATVMPHNLYLHSHIVKFRTPKNEGTTEDNLGVPLFVETFDEPECNEVSPLNVSTQVSSVTYNTIPADYMPLVNPNSPFNYFKLIKNAIMYSNYDSILALSVALLVNSSILIVAAAAFYKIGETNIAELKDAHSMITANLGPFAGFCFALALLLSGQSSTITGTIAGQICMDGFLGNKIKLAPWLRRIITRSLAIVPAVLFAVFKGEDSINDLLVLSQVVLSLQLPFAVIPLVYFTCSKEIMTIKHKVGNEEYVEKSYENSKLLGFLAVIVSIVLTFLNGVLIYQSLFMDETKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZI2</accession>
    <name>A0AAD5XZI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Polysaccharide lyase 14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000330">
        <property type="protein sequence ID" value="KAJ3219717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZI2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048958">
        <property type="entry name" value="Polysacc_lyase_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124:SF1">
        <property type="entry name" value="DISAGGREGATASE RELATED REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21294">
        <property type="entry name" value="Polysacc_lyase_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042296450" description="Polysaccharide lyase 14 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase 14" evidence="2">
        <location>
            <begin position="116"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="322" mass="36014" checksum="431D69030033CD7A" modified="2024-05-29" version="1">MKTLIILLNLVFFFNAIDARKSEKWLKKHGESQPLTTIFDANERNLQKKLKKNKKIKKVKSSDKVQEYTTSKIGVKSWSLLNFNGVDDAYEALYGQHQTGSDSKWRSIVDDPLEGGDKVMMVEYGAGSYGSKSNGGQTFYAQPPIDWENAKKVKFCYEIMFEKDFDFKNAGKVPGLWGGPAENCKLPDTCWSARFMWRHDGAGEIYPTIDLNKQPEGFCANPKQCLNGSGDQGISVGRGSFTFATGSWLPICQVIRATTTKGEMKVYINGDANPVINWENLVYAQSGFTGIQFGTFFGGGSDDASPKQQHSYFKNFSLEILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZM8</accession>
    <name>A0AAD5XZM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000412">
        <property type="protein sequence ID" value="KAJ3217738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051075">
        <property type="entry name" value="SCF_subunit_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872">
        <property type="entry name" value="UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872:SF9">
        <property type="entry name" value="UBIQUITIN-BINDING SDF UBIQUITIN LIGASE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="58"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="138"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="178"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="218"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="259"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="342" mass="38659" checksum="EDF2486189ECE416" modified="2024-05-29" version="1" fragment="single">PSSIPTPQPLMILEESSLIQSQVIPTDKYSTLNWNYIYAQKYTLERNWNEGKYLLQDFFGQKEACYCLEFDNEKIIGGSRDNTIIIWNIKTGRIQKILLGHESPVLCFASNDGYLISGSSDKSIIVWNLESGEILQSLVGHEESVLSVKYYEGFVISSSRDKTIKIWNFETGVLKKTLNGHREAINSLSVKNGIIVSASGDRTIKIWDFKSGELQRTLKGHSRGIACVQFDGDNCIASGSSDGTIKIWDVKSGDVLKTLNGHTELVRTLQFNKDMKLVSGSYDSTIKVWDMKKGKLLLDLKGVHKSWIFKIRFNKSKIISCSRDNRVLCWDFGLGVDENFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZW4</accession>
    <name>A0AAD5XZW4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anaphase promoting complex subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ANAPC7</name>
        <name evidence="3" type="ORF">HK099_004958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000368">
        <property type="protein sequence ID" value="KAJ3218711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZW4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF36">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="379"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="517" mass="59024" checksum="EDC0892B2C82444F" modified="2024-05-29" version="1">MSLPMISNKFYNDALNLFEQKLFYSSELILGKLISGFSNLNSLEVQQNLVLKIKTLELFADCLLENKEYFRAITYYKKSIQQTKIFKQKFKLHENFLRVKAARVAIFINEYKVAATILEGITENLRSIEVLKLLAKVYEENGQTFSAINVYKKIIEMQPLAIEAQLALIRLNVSLDDILTTSNSGILIKKKIVKPDFSAFGGMVGQGEQDYDQENWTHNFLQAHQLLFCQNYTRMVRKQDPEVLDQMDYYASTIKGKGSSYVINRLAEELLKISDERPEAWLIMAKYCEIKNEIEKALYFSDKAIALNKRHVAAYHLKGSILLANQDYELSLETYKKAHHISNDIFSFIGLVESYIGLKKFSEAELFSIDCHETMKGNPLAETLRGQVLFKTKKIPESIELFRHAIAIDPKCSKAVSLLAEVYVADEKYMEAIDLLEATLENNHNSGILTLLAECYIAISNFDKAMQHLNNSAMLNQDCLKTKNLIERVEKLINGTLTEPEDMADESMVVEDTSLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y000</accession>
    <name>A0AAD5Y000_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004829</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000353">
        <property type="protein sequence ID" value="KAJ3219062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y000"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3219062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="47503" checksum="F202F9942DAF3AC8" modified="2024-05-29" version="1">MNKSSKKIKYYSFSLLLLILILYATFIYKLQEENELALATEVEKNSAERGSTFKPFDHSFEKGLKNLKKELIFDKMFQNILKPTKLEPFHFEMKGLFEPSDITLTTMITVDRFDILLNCMTIFDGLFSVALHIAEDSDLSENLEKLKIFISKNREFIETRLDIHLVVDKFPRQLNYLRNVARFFSRTDLILPLDVDFMINKSFIKHVKSNDFIFGKLLNGEAVFIIPAFEYHGVHINTTYESFPQEKKDVIKLFKEEKLMIFHGTDNKGHTSTNYTMWMNTTDPYRIEPNSFSYEPYAIFNKNTVPWSDERFIGYGGNKAAWWYEIYLAGLEFWVVPNDFLIHQYHKYDDSVRLKERHRNVKLFWNFLPEICNRYRVRLLEHKNEHIDLMGCRPGNNSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0N5</accession>
    <name>A0AAD5Y0N5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component SEC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007204</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the exocyst complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SEC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000068">
        <property type="protein sequence ID" value="KAJ3225192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0N5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029175">
        <property type="entry name" value="EXOC2/Sec5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039481">
        <property type="entry name" value="EXOC2/Sec5_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15469">
        <property type="entry name" value="Sec5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC2/Sec5 N-terminal" evidence="6">
        <location>
            <begin position="131"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1191" mass="137872" checksum="F6F4AF3542B64994" modified="2024-05-29" version="1">MQPTQLKKNNPNNARSSTVSNSKGNNESTVIRRKFADDQDSEEDSEEEEKPEVNVLVQKQPQAQKLSLNEQEQVVQYYKLESFTQDYWLEENATEESVSQRISKIKRNQLLSNTSKNMAIFGNTEDDDTLDPLGKNDDVYREKRKALMKGKSGDENILKPNLLITSKNFDPKFYLNEVHINATYNDLVQGSATLKTSIQHRNDVMKNLVKTHFAKFVSAKSTIDSFYHEMRNKNLISSTDFGIAPFVTTLNTLSEDANKLYGPMLERRAKAEEIRTTLSVLDQWKFFFSLPATIKELIRKHKYDAVIRDYNKGKSLMLSSFPTAIPVAGPPEVKPKATQPSIFQNTVAAKTTVAKSASKVTGEKDNLLSQHHQKVFEKVWEEVNRIISDFSIQLLFHLRNPRLPLESQERTMSYLVELDPLGDPVWFYLENQYSYIIDQIDSSYKIHQDRLDALMKLSNGVLLPAESIAALDDEMEMEEFLQQSNTFNNEKFFVKKSEPFDVIFLKKVMNTLNSRIEFENLFSNDMDTLLWKSNFNLIKKICSILKSCIPTFGKVCKIFIEHRLEKDKKHLDLKKQELCHQMLQNMLNFASALISNTFFLEKDLTGLKNDLECNGTSSSNANDGEVSDILSPQSKIQKNFNTNDTSFKNNNKIFNGNEILNLSRKPSYVVKNPLSNNSGGEKTDNLNNLKLPVEFSIYLFSHPLKSLFYTTKICDEVRKFLFFFNDNNFFGLNTLILELCNEIFGSVNENLKDRFINCICDSVLLESKNFFLYQDWKFEQDISAHSKFFIGQQMETSTTTIVKLFYRFLKYTVRSLHSIVSTNEVNNTNFMDSPVSQLIKNLPNEEGENQIKRNYIERIRQTFYESLYLFLDGLEWLGVHWNENLQMRNGFKPSCEEQYLESSRPSSTKYNDLIAESWWEGERYGEFGKYDSMLGIHTIIGSIIAGKHSAIGSSRRSSNIDIRRSDIRILVIISDLQFLKSNMIPKLCQLFENKFKVFCSNDTHGLVTSVEYLDEILFRNYCRRKSKPIIYLLKNGILKSGLDWYDLRKPQGVRSFCYEALLLLVMVHAQVSDVSKELVKRILNELLHNFAQELLINFRQVDKFSLGGMMQAHLEIMFLEETLKSYENPEIKGLFDIVKESIEENCEIMEEKKKNSSSQNLNKYNEMLNQVNKFLEESKRSTFVQFSCFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2F5</accession>
    <name>A0AAD5Y2F5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">7-dehydrocholesterol reductase</fullName>
            <ecNumber evidence="18">1.3.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Sterol Delta(7)-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">HK099_008458</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>7-dehydrodesmosterol + NADPH + H(+) = desmosterol + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:46740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17737"/>
            <dbReference type="ChEBI" id="CHEBI:27910"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:46741"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>cholesterol + NADP(+) = 7-dehydrocholesterol + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23984"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16113"/>
            <dbReference type="ChEBI" id="CHEBI:17759"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.21"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="21">
            <dbReference type="Rhea" id="RHEA:23986"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Steroid biosynthesis; cholesterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.21" evidence="18"/>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2F5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047598">
        <property type="term" value="F:7-dehydrocholesterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016132">
        <property type="term" value="P:brassinosteroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1630:FF:000004">
        <property type="entry name" value="7-dehydrocholesterol reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF38">
        <property type="entry name" value="7-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01017">
        <property type="entry name" value="STEROL_REDUCT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0152">Cholesterol biosynthesis</keyword>
    <keyword evidence="5" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15 24" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="17" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="16" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 24" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 24" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="420"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="23">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00038851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00039984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00042688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00047826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAJ3224438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="483" mass="56276" checksum="EA76F19669F613E7" modified="2024-05-29" version="1">MAKDIKPELRQRNATSSNNYSSSVTNDSKTNFNENKLAQVGKTWGRARDVSFADILPPFFIMLLCPYLVIYFWTSCTHYDCSITTPILLLSEKGFTIDTIADFIFENFPKPTVEGFLLYFGWLFFQGFLYSILPGKIGFGQTTPAGHTLPYIVNGTLAWIVTHGLFVALSLGLNLFPASIIHDNWGGLLIAANVQGYLLSFFSYWKAHFYPTFADDRKFSGSWIYDIFWGIEFNPRFGKYFDFKLFFNGRPGIVAWTLINFSFAAAQYNNIGYVTNSMILLNWLHFLYVIDFFINEDWYLRTIDIAHDHFGFYLSWGDCVWLPFMYTLQSHYLVRNPIDLSWEYFSLVFFIGHFGYYVFRATNWQKDVVRRTNGDCLIWGKKAKVIRTKFETSDGKIHESLLLLSGFWGVSRHFNYVGDLLISLAMCLTCGFAHLLPYFYVIYMTILLVARINRDHHRCLGKYGKYWEEYCRAVPYKLIPFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2I7</accession>
    <name>A0AAD5Y2I7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000057">
        <property type="protein sequence ID" value="KAJ3225587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2I7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF4">
        <property type="entry name" value="CHM, RAB ESCORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="546" mass="62033" checksum="BC5F011222AA1109" modified="2024-05-29" version="1">MTTHSSEFHFENIILGTGLTNSILAGALAKQNSKTLHLDKNDFYGETGQSNNPAEILKCLLNSSLLIKINDEQILKSFEILGDTSELQSFLSTLNGDERMLVEKLLESNAIQFVEEIDFLQKKNKEEILIFKFRVLLLFLKDLRRTSLDLDPNVLRSNSSMVELLVKSGVGRYMEFKALEKIFLLFNDSVIEVPQSKEGIFSDSKINLRDKRKLMKFLNLINNAEELNAMLEEFGNTPFQEFLTSKGLDAKMIKIVLHALSFVIDGDESIFISTKDGVCRLTNYMKSIGMFGGSTGYIVNIYGLVSELYYQLFRYAAVNGCTYILRSDIKSVTHDNEKGTYTIAFMEENTKYTCNRLISSLEYMNLISTNLDVNVVYNSRAIVLQKKVEDENYKLTVFPPEAEHQGVVSFEQPLFANVAGIEICNTPESDLNWNPDLTSSLTPQKDYRSIAPGSEKLYLAPENDQISKFAYFNRDARRDYPQTVIFTQSEISKRITDGKSPESTTYTADKLPPVVNLKRKWVRSCEHFEDAKSVNPDFSIVGYRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2T3</accession>
    <name>A0AAD5Y2T3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000069">
        <property type="protein sequence ID" value="KAJ3225167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2T3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="164" mass="18645" checksum="BCBED6645AC930C9" modified="2024-05-29" version="1">MSAEVQNQNSFNLHNNKEDDNLSEELKLLSQEFEPLKNKKSHFNGGEWDHDCDAPLGKKFKLLNDFKVYFESVDKSRKNLDVIFKVLKNPDEIKKNHPGSSTKEPEDTPSLMPGPVIMGGGGGASGFGRDNEVVYLYWRNKHDYLYFTVKGDEVVGVDWYNAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSI7</accession>
    <name>A0AAD5TSI7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002136">
        <property type="protein sequence ID" value="KAJ3199332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSI7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="312" mass="35517" checksum="276B5EA93332F64C" modified="2024-05-29" version="1">MILSKTSPLSNDLIHHDSKKSDKSLKIKLSSFFKKIIREEPKSTQTQPNKVVINSNLSRSLEKKSTTPISQKNQTIPNSDNVSYSSSSHTSNTESQSTLIDTEKRVTAFLFSEEKHFFDSTNTLPVSDLNEFSSNHHQNYNSNFSHSEISSSALPKSTDANRPLTSISDAAMVYRPNSGKNKFLNSDDYSFEEELDGCETKDLNNETQYHHVNNDHNSNNNNLPAKIFIQTTDGKIFEKPKLSELENFKFDLRLILNELKVEIVKELEFGFNCKHVVEIGIPGPFQPTIFFEVYNRGGNIRFRRNSGDERLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TST0</accession>
    <name>A0AAD5TST0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002127">
        <property type="protein sequence ID" value="KAJ3199379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TST0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031101">
        <property type="entry name" value="Ctr9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14027:SF2">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="130"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3199379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="26969" checksum="1BD67724DC967387" modified="2024-05-29" version="1" fragment="single">MIFAFEFLKTNLIDEFVSFLRQCLTTVQDNPRYYEGQVQEHCLVANTLLAYYLNLARSESDKLARENYIGNALENQFKEAHYEFNTVLKDDPNNVPCLLSSASLYFDTKDFSKALEIYQKILTLAPDLKPDVRNSIGHCFYRLGMLEEARYTFCRVLERDENNVEALISLSIMDWNMFKNTTLELSKEEREIYLKNANARLNKAFKLEPTNSVVNITMADRLFKREDYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTC3</accession>
    <name>A0AAD5TTC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001835">
        <property type="protein sequence ID" value="KAJ3200793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTC3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042045699" evidence="1">
        <location>
            <begin position="19"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="101" mass="11244" checksum="FADED482D6BB6905" modified="2024-05-29" version="1" fragment="single">MKLTFMIISVVYISSILAKQDYNPTNYYIQKDCPKTCNVETALNATNTTQVNQNVTNSSDIDNEVQNTTTTIKTASTSTTLKVIFPNYDNLQNTALLQTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTZ9</accession>
    <name>A0AAD5TTZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001754</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001528">
        <property type="protein sequence ID" value="KAJ3202734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="216"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3202734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="224" mass="26078" checksum="5DAE9C8CF9171044" modified="2024-05-29" version="1" fragment="single">EDINVNLSSLTVEDGINLQETLLAVPKMATKRNNAIEKQLKKDQKEQKLKGIKILVLGPGDSGKSTFIRQMRLLGSSGFTQEEKDYFKIIIYENIVTMLNSLLDGLKFIENSQIDISDEVKNSIKTFNYQTLFNEKTFKILKSIWENPNIKLAYEKRKEFNIVLQDTSLYFLDDLDRFLDLKFFPLEQDMINCRKITLNITETSIVTKDTKMRLFDFGGQKHFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU77</accession>
    <name>A0AAD5TU77_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Argonaute 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AGO1_2</name>
        <name evidence="2" type="ORF">HK099_001168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001305">
        <property type="protein sequence ID" value="KAJ3204394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU77"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Piwi" evidence="1">
        <location>
            <begin position="58"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="302" mass="33298" checksum="055DA59EBB570F82" modified="2024-05-29" version="1" fragment="single">MTVLEVRGDIRQTLVTAKKKAAEIGQKFAGAKRTNSRSVDLVLCVLPQARNTALYNEELVVDQKGGYLGNLILKINAKLGGVNTYVLPSDIPLNTGSRIPTIVIGIDVTHPLAGVTNGISIAAVVGSVDSGYAEYRCSVRVQAGRQEIVDDLHDMVIDLFEMFRERSKGVYPQRVIVYRDGVSEGQFSEVIFNELKSLKRAFVTLKMNKAPTVTFLSVNKRHHIRFFPTNQKDGDKNGNVMPSTVIDTGIVHPYEFDFFLNSHPGLQGTSRPTHFTKAVSIVPAYHAHLVAARARAHVEKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVC8</accession>
    <name>A0AAD5TVC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001779">
        <property type="protein sequence ID" value="KAJ3201123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVC8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018859">
        <property type="entry name" value="BAR_dom-cont"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10455">
        <property type="entry name" value="BAR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="214" mass="23881" checksum="41E507BF4FE372F8" modified="2024-05-29" version="1" fragment="single">MTAEAKLSFNDYSRPAQDSLTDFASFFQRNVLNGVSQAEAKLNEIEFNPQPKPKSDTPQSLAHAFGRVGYYGSFVYSSEDPTAIALKKFSESEEKIGDLKLKFDSEAVEKFHKKLASLTIKLSESNSFRRHVLATRLSYDASRASFKSSKPEKVDEAKAKMEQAEDAFVKAVDDSMAKMKSITENRDFLPALADLVAIQLSYFKSAHEILAELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVM6</accession>
    <name>A0AAD5TVM6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CPR2_2</name>
        <name evidence="9" type="ORF">HK099_008557</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000953">
        <property type="protein sequence ID" value="KAJ3209218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVM6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000001">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042004043" description="peptidylprolyl isomerase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="8">
        <location>
            <begin position="157"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="293"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3209218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="323" mass="35324" checksum="5FA5DD7C80BC4A5F" modified="2024-05-29" version="1">MRFFILLSIISLAAANNCVASCDVNCAQKPRSEMCIKIFYPFATCFNKLPADACRETSSTNSTCQWHVPENFTSCLEKQDVDFEDIEFLNVVLDDNSTSVDNSTSTTTDGVATATSSQNPSATASNISSALIMYNFNLAAIVLIFGAKGPRITNKVYFDIYQGDESLGRIVFGLYGKTTPKTAENFRALATGEKGFGYAGSKFHRVIKNFMIQGGDFTRGDGTGGKSIYGEKFADENFKLRHNKKGLLSMANAGKDTNGSQFFVTTVLTPWLDGKHVVFGILLEGEDVLDKIENTPTNPGDKPKVDIIIKESGELPLEEKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW85</accession>
    <name>A0AAD5TW85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000754">
        <property type="protein sequence ID" value="KAJ3212990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW85"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="153" mass="17492" checksum="125C67092F7F21A1" modified="2024-05-29" version="1">MKSLEFYGRCIGLVICYPKTFQNEVAGIVEIGGLKCYHRVIDRTNVNAPNLKLKNRKEEAEDENEIFFLLEKKILIKLNRIKKSDTEVLIGVRCFFFVCVIKNNFSGCGKTATCYQLCRTRFALYFDGCAGNNVKSLMTVCDNTFQEPCMISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWA8</accession>
    <name>A0AAD5TWA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000842">
        <property type="protein sequence ID" value="KAJ3211313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWA8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="208" mass="24426" checksum="2A2B4E950FACF137" modified="2024-05-29" version="1">MSTTSIQQTSTRHYKVCQFKDNTSSFRKIEIESLDVIFKDVFDINDIERKIIDSFVRLSRSKIKIIIYIQKNHEQIPLFLICSEKWVHTKEISSIYDFSVERKRIIMLVEEEKNSRNITVIKGRKLIKAAAYNNLNNIPIIYSENIYGVKVVGLKFTFYKAVKPIDDLTSLTDGMPDMNIRIYRFPPQGNNKELQALNYSIGDDRKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWX8</accession>
    <name>A0AAD5TWX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DBH-like monooxygenase protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MOXD1</name>
        <name evidence="4" type="ORF">HK099_007579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000747">
        <property type="protein sequence ID" value="KAJ3213093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWX8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030667">
        <property type="term" value="C:secretory granule membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042421">
        <property type="term" value="P:norepinephrine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006589">
        <property type="term" value="P:octopamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF23">
        <property type="entry name" value="MOXD1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042282769" evidence="2">
        <location>
            <begin position="19"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="3">
        <location>
            <begin position="48"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="230" mass="26228" checksum="B42B2AD24BD94635" modified="2024-05-29" version="1">MLLNSFLFALTIVPSAFAIKKTEAQSWIPFNTDNFTSHTELITQRHKLSFDLFWAHHEDEIEFGFAAKGRQGWIAFGPSLIGEMKGSDIIWGYTDPLDKKFKVQDRFMKLDAIISIDKVQNLEVISGEQNENGTAFTFKRKYMLCNEEDLPILSTQRFIFAAGFSNERNLHEDRGTMEVQLGGKFNSPCINENIKNVANTEEKKSSAQKSVFINLINVLGIFLFILAFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWZ4</accession>
    <name>A0AAD5TWZ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">70-kilodalton heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HSP70_3</name>
        <name evidence="3" type="ORF">HK099_003413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002238">
        <property type="protein sequence ID" value="KAJ3198892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWZ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000020">
        <property type="entry name" value="Chaperone protein HscA homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000003">
        <property type="entry name" value="Heat shock protein 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3198892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="26543" checksum="B7CD6B6C260C238D" modified="2024-05-29" version="1" fragment="single">EKVQGSVIGIDLGTTNSCVAVMDGKTPRVIENSEGGRTTPSVVAFSKDSELIVGAPAKRQAVINPENTFFATKRLIGRTFNDKHVQQDLKTVSYKIVKHTNGDAWVEARNKRYSPAQIGAFILGKMKETAEAFLGKTVQNAVVTVPAYFNDAQRQATKSAGQIAGLNVLRVINEPTAAALAYGLDKEGGDKIVAVYDLGGGTFDISILEIQKDVFEVKSTNGNTHLGGEDFDNLMVNHIVKEFKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX44</accession>
    <name>A0AAD5TX44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000686">
        <property type="protein sequence ID" value="KAJ3213686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX44"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="292" mass="34246" checksum="45B2D1B43FCFCB31" modified="2024-05-29" version="1" fragment="single">VHGEKEKMGFLKQRIVKELKIPTFYPANGVSINLDAENLVKVKVSNLIFDQAVHDSKKILFESRLKKKLERPNEKINIVGNLKEAKPVKYLSFSKLEGKFNGENFTLYDNTLKSKNTEFEKKKENIALFANANQLDKIGNDDETSEKVEKVFKRTYNPIPLIYKDNDEKKEISLLKKKREFIDEVIKPNFKVLAIKKLFSNLESKFNFIYTADNKSNSSSQKANTDLFDDNEEKNYKPVLYKNEIFFKSIRIKHFEKNLKDRECDFGFEINWLEKDNLYAIRIITILNSTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXH0</accession>
    <name>A0AAD5TXH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002682</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001903">
        <property type="protein sequence ID" value="KAJ3200450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXH0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007258">
        <property type="entry name" value="Vps52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048361">
        <property type="entry name" value="Vps52_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048319">
        <property type="entry name" value="Vps52_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190">
        <property type="entry name" value="SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190:SF7">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20655">
        <property type="entry name" value="Vps52_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04129">
        <property type="entry name" value="Vps52_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps52 coiled-coil" evidence="6">
        <location>
            <begin position="2"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="7">
        <location>
            <begin position="58"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3200450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="209" mass="24007" checksum="5B2305FBBEB42103" modified="2024-05-29" version="1" fragment="single">ATDKIREFLLKKIETLKTPNTNISIIQQSIFLKYKELFWFILERYSEAATEIKINYVNTVATYYFSSFEKYLKSTQKLQMIIADKLDLIGCEENAKRGGLFASKINLKDKSNVFTLGERIQVLTNADAGIILGHIAEEQNIKYPYEAIFKSVNRLLIDNSSSEYTFTAYFFCSPKLNNKVNQSNLNNTTSTDLNLANLIFLEIFDSTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXR3</accession>
    <name>A0AAD5TXR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000593">
        <property type="protein sequence ID" value="KAJ3214763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXR3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36851:SF1">
        <property type="entry name" value="GLYCO_TRANS_2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36851">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="2">
        <location>
            <begin position="152"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="620" mass="69678" checksum="0079DC3E10733FE0" modified="2024-05-29" version="1">MAYGIYNAYHKSILHATTNWLEKYCNETGSSGPSDTSHDLPFSDIIHVIILPNFSETLETLCETLDVLASHTMALTQYKICLAMEETEFGSKQKALVLMRLYSDSFFEIVYTIHPANLPGEIRGKSSNVAWAAKEMAHNAADGLKGRHSHEIVTIVDADTCFAEDYFTSVTYHYCTATPEQRKMLMFMPPTVFDRNLNQVPAFVRIYDIGWSIGVMSNFHDSSIIKFPCSAYSISMDLCVTVNFWDTTPEAIGEDFHMYLKCLFSTQGRVIVKTIFSPASCCNVEGIGNGISGYLDGLKAKLIQSIRHMWAALDIGYILRRILLGVLAPEYDLMVNQSSIADDKLIPNRSKFGGLTFKLFVNLIHRALEAQTLIGQAFLFMLFSLIIIPSGGSHGYIWNLLTTSSVHPYVELISKISAFTQLLILIPNVLILIYYQKYHKFVGFERWILQPMDKKESLTINSKSKFFQRSHLSKANKNFKVSRLGRRPTLFSERSLKKQFVEGLFTPIFVGVLYYLIPVFFCQIKQLFTDKLDYQVAGKPTVYNSNVSSGSDNNLELLLTKNMNDINSGNDGSINASANNLNNIVITLHQNDFNAEGNDLVEVLSDEGYGGSDTSFCSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY38</accession>
    <name>A0AAD5TY38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006285</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000531">
        <property type="protein sequence ID" value="KAJ3215621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY38"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="5">
        <location>
            <begin position="507"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="5">
        <location>
            <begin position="584"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="181"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="373"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3215621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="922" mass="105161" checksum="C864389F0DCB7089" modified="2024-05-29" version="1" fragment="single">MVNQPSSNGGTKNVINRRGTMLPPMLSTFETKVNQNGNLGIVKFQLKTPGLIKLKRLVNFTLTNSQQDLVESKFLGNKNKDVYTGFLSGKSKLYRATIDKKVLDKVEKEKKQKKKEMISKGEFIVERSPRITLINGTRPNRFETEKIKKELKKTEAKDFLLRKWQHMQGLRVSAISTIQAIKFYKDEFERLKNENARIQKNHAQIKEAVNKDISVRLEDNENMELKAAKLFENLIQQKKDQFNQFRIIENTCLNDQKVYLEELKVLEIEYQDMMEESSKLIIFKELSETDPESFQKVIEELNSKLVMMQAEEDKAIELLQFKNEQELKEIETKTLIKMAEIDEATGKVLQKKIKPSTPVSNAVFNNSILKKEIKLHKENHIKIDLEIENLEKAKLTLESNLKNFNEGNFGDVIVEKQCNGNNDESETGCKEESLNVINAGLSQLEKFTGPGKSKVGGRYLLGSGINDFRNLKEKNLKKFMNCQPEMEFKFEKEQSAEVISRKSNAARILELNRPKALNALNLNMINIMKTELESVQNSSLCKVVVLTNDENLKAFCSGGDVKTVVKEAKSGSFDNALNFFRTELFPDVGGSFFLPRLDGEIGTYLGLTGHRLKGEEVFMAGIATHFVPSSRLSTLLTHLSDTTSDDYDVVNMILEDFVGDPIPYSQWQNWSLGGEKRTAIDRCFGFNTIEEIFDALQNEQSEWGEKTLKKLKTFSPTSLKVTLKQLRFGKHLSFADCFKMEYAMVHEFLKNHDFAEGVRALLVDKDQKPNWKPTFLDKEQLSEENIENTYFSILNPAAKSQKTTVALELLNNRTYLDYPHRTLSGLPSENDIQRVVSNEGLNTKQPLISYADVLNYFLLNWGKYDEKLMGQYVSRKNCSIDGGLGRGKVGLKEKVLSVLTKNAVEEKDKDGTVVGLKWSSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY39</accession>
    <name>A0AAD5TY39_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="3 11">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NDK1</name>
        <name evidence="13" type="ORF">HK099_006580</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3 11"/>
    <dbReference type="EMBL" id="JADGJW010000579">
        <property type="protein sequence ID" value="KAJ3214964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY39"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000002">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="12">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="9">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3214964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="132" mass="14608" checksum="83985BC02706D78E" modified="2024-05-29" version="1" fragment="single">MSNSEQTYIMVKPDGVERGLVGEIIKRFETKGYKLVALRQMTPSREHLEAHYADLKSKSFFPKLLNYMLSGPVVGMVWEGKDAVKTGRRLLGETNPLSSLPGTIRGDFCIDVGKNLCHGSDAVESAQHEIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY43</accession>
    <name>A0AAD5TY43_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000605">
        <property type="protein sequence ID" value="KAJ3214612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY43"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF1">
        <property type="entry name" value="3BETA-HYDROXYSTEROID DEHYDROGENASE DHS-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3214612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="605" mass="67387" checksum="6217D04D6252FA5E" modified="2024-05-29" version="1">MSLLSLPSYILRQLSGSTDAPTYETVLKLHNADELTLAPIPEKLTETLEKPNSEDNSFTANIDLLGLADWASTTWNNAIGLVATKVLGLPFEFPVYDNGIIIVTGAGSLIGFHAAKTLALKGFTVVAGLRTEQEVVKMETWITAQKQSDKPKINLLPIILDITSDESIKQAVTYVENLTEVLVVSTNGNLENLKLIGVVNCEATSSMGPLELMSHVELTRAFQVNAGGMVRLVQGFLPLLRASKGRVVNLSSSAGLFAANGSYAASKMALEALSDSMRLELFKWGISVSIIEPGAVDPRVWLDASGKENQNHIPLVDIDDEDESPHLPSGRRQSIDTRGRNRNLNSNNSRARSTSNTKSLLKKNEPTPLEGKTPVFNEQASKLAPLYMPMMQTLADLAREHSESLGDKAPSARPTTRAITHALFAQYPMTRYLCGWNAKVAAAVKWAMPDRIIDMGFQTIMMSNEEEDKEIIGVERLLCNMDKDAPVRPIMILALIYVSRLAKVDSSIIDNLPLVWLIAVNLSKKYLMDKNVTKRNNLLQKVFSLENTSRFELLNLVKLETHFLKLINFELFCRREEYEYWERELKRMSLIFFVNQDRFVTSVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY79</accession>
    <name>A0AAD5TY79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000554">
        <property type="protein sequence ID" value="KAJ3215295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY79"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="438" mass="50024" checksum="21BA09C94DB72773" modified="2024-05-29" version="1">MQLFEKNDTYWNTFSIETASICIGITLVITSETLFKHGLSINVNKDRDRQKLLSFICLVGAINCCFYYGLSQTRLSTLLAIMSGLIVQFAGQFGVIIIFHNSIVRLMTSSPRNAKKLRRKRYKNFFVTLYFYPILCLAPTYYAIYYFINNNNNIPSSDTYLLRIQRGISLLNILVMEIFATVTDVILMNSVNKVLKDSYLSAEEDNFEPPLQTYPMDFHLPSNEFPDSGTIESVIPLAVEYDANNEVYGSASTMPKTFSAPELNKQLSVHDLQRIAKMNSTVLQYKWNTSEDYLLPIHKPNFTSKKKEVNFRHTHEENSESEIIVSSDCGVSRASSSKQSKNYISMISQEPSLGKLSNKLRNAHRSLHKGLPNALHLNYYMIWLTMALDFVVKVLIMTGYNFRIDGITTILMIALRGRTNLEFGLNLEKIFGRKSLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYC3</accession>
    <name>A0AAD5TYC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Twinfilin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TWF1</name>
        <name evidence="9" type="ORF">HK099_007685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Interacts with G-actin; ADP-actin form.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000769">
        <property type="protein sequence ID" value="KAJ3212642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYC3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11285">
        <property type="entry name" value="ADF_Twf-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000042">
        <property type="entry name" value="Actin depolymerizing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1530.10">
        <property type="entry name" value="Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028458">
        <property type="entry name" value="Twinfilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759:SF1">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="ParB/Sulfiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ADF-H" evidence="8">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3212642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="568" mass="64157" checksum="FB51BFD5F2938BC9" modified="2024-05-29" version="1">MSHQSGIKPSQELLDFWQTALNSNSIRAIKISVKDEELIFNKSVDCSGNWKDDFSLISDFFESKSPSFVLYKLDTKEPPKIEKGNWTENQESGSGLYIPDFAPVRSKMLYASTKATLSKELGDSSFVDYYYGSTKEEFTLNGYREHREHQNAKVPLTEREQEILSIKENESANIGISARKGYNPMNSELGGFSIPVTADAEEGIDMFVNGSQNLVVLKILIAEERIALDFFDNLDVNNLSTNDKMRESNGLIEPRYILFTWNEKKVFALTCPDTSKVRERTLYSSMRASIIKFIDDKLGVGNELAKKLELDAVSDLNDDNLKYEFGYLESAGQEKEEKKVFSKPMKPGRGPSEVYENGYVVKDPFFHFPTPQIRWVDPEGLVPHEYTSANGLKNLLKHLETLSTTSPLPMPVVTSSYPPVILDGHHRVAASIAMGITRIPVWIVDIGDDDPPSNVKRTFEEELSREEERTSIRCYATKDNSRIKISDIAKAARAGTIGFGIKGTRHVAIVAHNGLEVKLEKVTPRIMWGVWARYKITLQELNQFISFSSGRLNATDIIIHQQNQLRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYG8</accession>
    <name>A0AAD5TYG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005673</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000452">
        <property type="protein sequence ID" value="KAJ3216947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYG8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="5">
        <location>
            <begin position="54"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3216947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="242" mass="27796" checksum="7465AE247D6DEFCC" modified="2024-05-29" version="1">MINDVTTADVQNKKKRIFDSIDNEDNSQFNNTNSLKADVSSNDLLESSLRRMKHRSIEGNKQYKLVMRQEPVHVRMCGGSDKDRRTIDPPPIVEVLEVDEAGQLYPIIKDSGFFIMRVELWNEAKTERAKIRKRINKDLPLILGDLVMGSRVLLDDLGRTGTFFVFDDISVRYQGRFSLKFKFYDLESEDENDCLVSKATIKTDIFSENFVAITAREFPGMLKSSQITKVFKTQGLKLSVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYQ6</accession>
    <name>A0AAD5TYQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005983</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000492">
        <property type="protein sequence ID" value="KAJ3216198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYQ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="396" mass="45593" checksum="CD8E913437AB3BF4" modified="2024-05-29" version="1">MHMYAQIHSGAESHKNISKSSNKLLHLYYTNSNVLFGVCAGISVEINFNASNTNVDIQTDTLEDALMNLSNDLILDKIFQTVLKPSKLDYYHFKMSENPEISDVTMTGSVSIDMLDNLLVCLNNYKGPLSITLHINDDNNLQLNLDTVKSFLNNNFAVLKKQLDLHLIIDNFPHQHNYFANVAAFFSRTDLILPMDFNFISSTDFSLNKYEGVLSKLMDQNNKVLYIIPSFEKVQSENAWELTSQFPHSKKGLMEENRYQIYGGSDNRAHISTNYSEWYLANNPYLTASISFFYEPFAVFNKHVVPWMDERFIGSNGGGRSAWFYEITLSGFEFWVLNDDFLIFSNTPTSLANELKNKTFWGFLPEICNRHRVRLWESEKKEIDLMGCRPGPNSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYU2</accession>
    <name>A0AAD5TYU2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005946</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probable zinc protease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000489">
        <property type="protein sequence ID" value="KAJ3216236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYU2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.70.10:FF:000003">
        <property type="entry name" value="Disintegrin and metalloproteinase domain-containing protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051489">
        <property type="entry name" value="ADAM_Metalloproteinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45702">
        <property type="entry name" value="ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45702:SF2">
        <property type="entry name" value="KUZBANIAN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041961012" description="Disintegrin and metalloproteinase domain-containing protein B" evidence="7">
        <location>
            <begin position="18"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="670"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="9">
        <location>
            <begin position="236"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="8">
        <location>
            <begin position="478"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="705"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="881"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="705"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00056552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00074021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3216236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="915" mass="100828" checksum="3BA71961A81E519F" modified="2024-05-29" version="1">MIKFLVSTFSFFLLINASPGTAPVRYYDFLLTNNIQLQFNSINLKFSAFNESFTLILEKNSDLLLPDSIVHLHDSLTNQKTISSIVAHPYKGVVVNSMNHEVGWARIMFHEVPLSESPNKLLFDGTFTNLNGMYHINTVANYRASRRPGLDIDLVSPFERNPLHKNSRLILFKDSHNEDDHKHDSLSNPMSATYGCGFEHSEANTRAILEARGNTFKLKKRQQAGVMSSCFGQTKRVLKMSVAADCSYTQSFRNPKTVLNQIISYWNEASQVYEVQFNIKLAVIEVKILQTCGDHNGEVLSWNKGCTDNYGINDRLSDFSQWRGQLAPDEAGLWHLLTACNTGPSVGVAWLSQLCVQGLSEQNQNGKKQFVSGTGVSSIVPVTWKVVAHEIGHNFGAIHDCTFVNCPATCDTSGLSTECPCCACAGCDCGGQFLMHPTDNSAKPQFSPCSLNYMCSNINEPVHSACLLDAATVNTIKENTCGNGVVEAGEQCDCGKGCATDSCCNNDCTFKAPAVCDDLNDECCRGCQIIPAGEICRPSFDMCTKEQFCNGKSATCEASIKLADGTSCNKQAASNTTKGTTCASGVCTSRELQCISLVGDSGPRTVGPCKNHENDCKLLCETENGICLSLSGDFIDGTPCVGGGFCRRNVCEGASLIGVGLYYFTSQPALAYPITIAILIVFLLFLYCFAKVVCCRGSKKKNRKIVNPKNKNKKNNNNNNESNVAQKYYPGSSTVNPSVSGSGNTLQQSSLSPLYNSSVIPPALAYNSQSNVGAKIPGTSNISESQQQSQTTGYHIEPIKFQYDSRKESNFTQQNNYIPSSQSQRHDYNYGYENTNGRSFNNNYGYNDGYNSYDNYSYNNDFNLQNDNNILYYQNESNEFKYQNDNNGFDAKESFNSNRENESRNKYGRWRPPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ01</accession>
    <name>A0AAD5TZ01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">transketolase</fullName>
            <ecNumber evidence="4">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">TKL1_2</name>
        <name evidence="16" type="ORF">HK099_006361</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="12">Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000541">
        <property type="protein sequence ID" value="KAJ3215465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ01"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="15">
        <location>
            <begin position="350"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="111"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="521"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3215465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="687" mass="75943" checksum="CC3882C814750AE4" modified="2024-05-29" version="1">MLEIDTIRTLAADMVQKANSGHAGMPMGCAPMAFVLFTNFIKQNPKNPRWVDRDRFVLSNGHGCALQYIIFHLLGYKITMDDLKNFRQVDSITPGHPEAKHGIEGIELTTGPLGQGISSSVGIALAEAHMAATFNREGFKIIDNYTYCICGDGCLQEGISSEASSLAGHLKLGKLIVLYDDNSITIDGDTALGFTEDVLKRYEAYGWHVSKIDDGDHDLEAIKNKIEEARSIKDKPSIIKIKTTIGFGSMHQGEEKVHGSPLGDDDIKELKKKFGLDPEKKFHIPNSVYEFFHKISARGDQSEANWNKLFENYKLKYPELAAELIRRIEGRLPDNFESFFPTFTPDDPAQATRKYSETVLNNIADHLPELIGGSADLTGSNLTKWKTAKEFQADSTGLGSYDGRCIRFGVREHGMAAICNGIASYGGLIPFAATFFNFISYALGAVRLSALSRFRVLYIMTHDSIGLGEDGPTHQPVETLAGLRALPNILNFRPADGNEVSGSYLEALKHQHKPSVLILSRQGVPNLKGTDLAKVRLGAYIIVDSLAGKKLDLIIIGTGSEVSVAVEAGKLLSEKHKLLVRVVSMPCWELFEEQSQEYKESIFSKDVPVLSVDILKNDPSVEALSALGWERYAHGSVSMKTFGSSGPYKKLFTKFGFDADQVAKKALKLIEFFKDKKPDWKVCRFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZI4</accession>
    <name>A0AAD5TZI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol kinase- protein kinase tor1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TOR1_6</name>
        <name evidence="2" type="ORF">HK099_006896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000625">
        <property type="protein sequence ID" value="KAJ3214396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZI4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.240">
        <property type="entry name" value="Ku, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036494">
        <property type="entry name" value="Ku_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014893">
        <property type="entry name" value="Ku_PK_bind"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08785">
        <property type="entry name" value="Ku_PK_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101420">
        <property type="entry name" value="C-terminal domain of Ku80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ku C-terminal" evidence="1">
        <location>
            <begin position="287"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="394" mass="45484" checksum="0A0275766762D930" modified="2024-05-29" version="1" fragment="single">MYALIKLTQESNENIPDVINLINKNIIQLINSKDKNNLIVGILVIDQLLEVELDYSDENNMKVTRFANYLRILLKSDDLEVINKSAHTLGRLVKFNRSYNSELVEFEVKRCLEWLQDEKATDSNRFASIRILIELGSLTEVTALLHSFFPQIIDVILKIIINDSKTIIRENGAKCFEVYIKMIILRSSKIPENIARRSFLEIERGVRINSNESIHGSLLILNALLSFHPNTFGAVIDGKYDHICKFVVGKKENKDLMIRKVLISLLEKLATFNSNLKDEVLEVGSVNPVSDFKKLIARRDDDYIATATNQMINRIQEFIFSSHSEDYFEKAINCIKVLKDACSKELEFEIFDSFLKNLKLKCVDQGRDSNYLKNFWNFFLDQKIGLLNESENEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZT9</accession>
    <name>A0AAD5TZT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alginate lyase 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005079</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000381">
        <property type="protein sequence ID" value="KAJ3218426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZT9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014895">
        <property type="entry name" value="Alginate_lyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08787">
        <property type="entry name" value="Alginate_lyase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042288169" description="Alginate lyase 2 domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate lyase 2" evidence="3">
        <location>
            <begin position="52"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="324" mass="35876" checksum="4188D361BAD0EB7B" modified="2024-05-29" version="1">MTLKSIFKLDSNFMLISIAFLLFSTQSKTIQEKAPIPTENHPKSENPTSQPFSLQNWTLQLPIGIGSKFETVKHPILTQPGDGFVFHTPVLPLNGVSSANSDFTRTELREMNATNPKYNANWDTVTGVHFMKVTQSIDKISSSTEGKLINFQIHSECCAVMTVRLFSKPETGVLLFADFDKFENGSLTKIIGADKYPLIENYVMGTKFDLEVVVDNGLVYVYLNGELKTPKEGYKTNLLGVYFKAGSYSQNLPSETIPATAVNQVTIYKMELYHGDGPYTPPTPSSPKTNSNDTSVDDSPALNSANGYSFSSILFILLLSFVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZU4</accession>
    <name>A0AAD5TZU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavoprotein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005787</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000467">
        <property type="protein sequence ID" value="KAJ3216639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZU4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071513">
        <property type="term" value="C:phosphopantothenoylcysteine decarboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF6">
        <property type="entry name" value="PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="3">
        <location>
            <begin position="7"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="119" mass="13563" checksum="13A81E37CC560C20" modified="2024-05-29" version="1">MNGRDPVLHIDLRNWADMILISPLDANTLSKLANGQCDNLVVTWDPKKPVILCPAMNTYMWDHPFTERHISFLKKELGYLFLDPITKQLACGDYGIGAMADVKDIVAFVKRVKEEFNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZW5</accession>
    <name>A0AAD5TZW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Radical S-adenosyl methionine domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RSAD1</name>
        <name evidence="2" type="ORF">HK099_005756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000463">
        <property type="protein sequence ID" value="KAJ3216725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="COPROPORPHYRINIGEN III OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932:SF5">
        <property type="entry name" value="RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="18"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="37876" checksum="FE0320C285CE1BF3" modified="2024-05-29" version="1">MLNSFKIDIDGALFDINERRMVKSIYFGGGTPSLSRPETIKQIIDYICSKSAVDKEAEITLECNPTSVELDKLKSFREAGLQSFDDSYLKFMGRDHNRELSLSSLTACDLGASQLSLYQLTLERGTPLFKQYFTNNVVPKLKLKSEEELSDFWDLTIETAERNDYLQYEISSFAKGGYVKNRSMHNSFYWNGTDYIGVGPGAHGRYTDPYSIRYRSFRVLEPNAWMSQCEQMQTGCKKTEKLSQLETNKELILFALRTIEGAVPELFFENSNGCKLEDFIDFNTLDHFVTHGYLEIIEEKDYKFGRGFKASKKGLKVIDFITKRILEACN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U062</accession>
    <name>A0AAD5U062_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SUZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004668</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000337">
        <property type="protein sequence ID" value="KAJ3219509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U062"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024771">
        <property type="entry name" value="SUZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12752">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51673">
        <property type="entry name" value="SUZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUZ" evidence="3">
        <location>
            <begin position="206"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3219509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="294" mass="33528" checksum="579F0C822973DED1" modified="2024-05-29" version="1">MSNRCKDKFLVQAIKIPEDLMKISKEDAQEKLQELWAIAELSKKTDSNSLTGIICEKRLKCVYLPSLESRNAVTHNDSKSQSFFDYRQKGSQLPNVQPSSSLSDLTEKELKETIKKLSAACEGYKAEIDRLNDLRKSKVLNEKGGEISTQSGATVALSEISGIKPLDAFLISLVAFLIEKELMSTSKSLVIDHWDDTVVEEDTYTQNPVTVITESSRSEYKPQIKLLQRKPEVAVSNKMETRTVSKPKEKTKEERELEYKLTREKIFNEKDEKLSSRNNSKLEEKKTTDHWDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0L0</accession>
    <name>A0AAD5U0L0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">JmjC domain-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">JMJD7</name>
        <name evidence="2" type="ORF">HK099_006209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000520">
        <property type="protein sequence ID" value="KAJ3215790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0L0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF99">
        <property type="entry name" value="BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="289" mass="33200" checksum="FAFF34FEFDBE662A" modified="2024-05-29" version="1">MDKLEKVCKKCSKNCRDFGLDVFILEGKPTPLQFSKIVGKNRPALFKGACKNLPAFKLWRSKSYLCDVMKNTKIQLAATPNGLADGITDNFFVLPHLIYCSFNDAIEKFSNAKKDVLIYDDKISYYIQSQNDNLQSDFKLLFETGDVPKEIFWASEVFDKKPDGEQCCLLITNMIHFYSDVQLSNDTIWEIKPLNSKTPWVSVNPQQAEIQPIIVEVSAGDVFYLPSLWYHQVEQESTCLEKGFNATIAVNYWYDLDYDDARFSYFQLLRSVTKLAEGTNIDDDEDDDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Y0</accession>
    <name>A0AAD5U0Y0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000292">
        <property type="protein sequence ID" value="KAJ3220553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0Y0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="52" mass="5822" checksum="A36D45974DC43BAF" modified="2024-05-29" version="1" fragment="single">MSNNSAPVCITCEIDFQCLKSFATDNLTKEEIHSTYNACLCEGDKRVDAYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U124</accession>
    <name>A0AAD5U124_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosylnicotinamide kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NRK1</name>
        <name evidence="2" type="ORF">HK099_003917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000264">
        <property type="protein sequence ID" value="KAJ3220910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U124"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="220" mass="25806" checksum="728C44DB272C8297" modified="2024-05-29" version="1">MTKSTLTGWLNKILPNSKILHQDQFFKKDSEIPIVNGIANWDCPEALDNENFLMTLKNCKKVGLKESVLNGNRPKLNSSEVDDMFINQLKKELLGSDSDLEFILIDGFLLYHDERFLKEFDISFFCLANKEVLIQRRQKRDAYITLEGFWEEPPKYFEEFVWPCYLKYNQKILKHLENKNAAAKDLEDNLKVKLLDSTETSIQNILEFAIRDIIHKVKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U128</accession>
    <name>A0AAD5U128_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="18">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">HK099_005436</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 18">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="18">Membrane</location>
            <topology evidence="18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="18"/>
    <dbReference type="EMBL" id="JADGJW010000422">
        <property type="protein sequence ID" value="KAJ3217546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000087">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000014">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF180">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 17 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 18" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="345"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="403"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="979"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1010"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1061"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1103"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1130"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1165"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="21"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="947"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1228"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1312"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1478"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1489"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="15">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="622"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="663"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="687"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="721"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="801"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="802"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="803"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="895"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="901"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="921"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="924"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="925"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="925"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
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            <dbReference type="ARBA" id="ARBA00022967"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
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    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3217546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1498" mass="169189" checksum="46545964D6C560AB" modified="2024-05-29" version="1">MSSNTTFVITLNGDNCTLNKNSNKIITTKYTFYNFLPKNLLFQFSNVANIYFFLLIVLQAEPTFSQNIPLIVVSTPLLIILLAVALKDAAEDWKRFQQDSVVNSYDTYVCVGRHRTKKKFGIHSILLNFILNPLILISQLFRRKTLVNLPEEIQLTDYLDIDSKETEKDYHNRFSWQKTKWQDIKIGEFVLLRNNDAIPADLVIISTSEPSASCYIETKNLDGETNLKVRNGIPQLSCIQTPFDCATMRGTLELENPDAHMYSFHGVANIDTSVLSSEKEHFKESLPVKVPLSINSVLLRGCFIRNTKWVIGVVVGIGADTKLMLNSGKTPTKKSRIDRQLNPQILLNFMILFTMCLACGVLGAIYQIAFNFVSNSSGEFINKPNFLETDPLKIILPIAEPTFIALLTFASCLIIFQNIIPIAIYISVDVAKTFNSYLIYRDQDMVDPATDLPCVPRSWNLCDDLGQIEYIFSDKTGTLTCNVMEFRKCSINGVVYGNGFISQANVGLLKRNGDGKCGNLEKNYSSNRLKEETEMRDTMSNLFDTRYVKADALSFVDLELHNDINLGLQSKVKNDEINETTEHAKAIIEFFTLLAVCHTVLVEYPDPDNHDNLSYAAQSPDEAALVAAARDCGFTFLRREDDLIFVDVMGTEKSFQILNVLEFNSDRKRMSVLVRKPGQKDVLLLCKGADSIIFEMLTKTEEKLLRSTTNHLETFANDGLRTLCLAYRIIPEAEYEKWAVEYAEALNSVESHDENVDALSASIECNLTLMGATAIEDKLQDGVPESIALLSKAGIKIWVLTGDKMETAINIGFACNLLSRDMLLIVVKSTKNVEETLKQIKDALTLFWSPDGTPIKRESHALIIDGDTLNFALDTECKDFLLELSCRCKAVICCRVSPKQKAQVVTLVRNGLSAMCLAIGDGANDVSMIQAADVGIGISGLEGMQAVMSSDYSIGQFRFLSRLLLVHGRWAYLRTAELVLNYFYKNVVWLFVLFWYQFDSAFTGDIITDYTYGMFFNTVFSLLPNMVLGMLDQDVNDQISLQVPELYQIGIQQKLYNMEKFWFYIFDAIYQSVVIYFMGVFVFSDSVINPDGLSPSKQEFGTYLSFYIICTVNLYMGFNIVNWTWITHTALWSTLLVFFGYVAVYLNFIAIYMPGVYDTTYLPNVFYMPMFYLSLILALTLSLFPRFLFKFSQQYFYPTDIDIVQEYQSYIWKDGDVVNLDIKHSDKNSSLKESDQSSVQTENEPNTDDLDSNTNFLRRKHNKKSSATSAVSSTQLPSITIDSPVETILRRQPRLIPSSMFFSSTSNCEHDSFENEADELPNTSNITNPPKSPKMLLHERIITPLTEFNKKTVEFVKSVPRLLRIPSLTPSWRLNPYGENRSMVFMGGEPVGREVPNTGFAFSHGEGMGQQIMGRSATLYSTTSYGERFDPPILVETDGCATPIKSVKKDDLTHENNFEGLRSRQLQQVKIDINLSPSIDISLNSPPPNDKHSSSHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U181</accession>
    <name>A0AAD5U181_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">fumarate hydratase</fullName>
            <ecNumber evidence="3">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FUM1</name>
        <name evidence="13" type="ORF">HK099_006390</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH. In cytoplasm and nucleus, involved in DNA repair in response to DNA damage: following DNA double-strand breaks (DSBs), translocates from the cytosol to the nucleus and promotes DNA repair by catalyzing the dehydration of L-malate to fumarate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000548">
        <property type="protein sequence ID" value="KAJ3215380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14478">
        <property type="entry name" value="SPX_PHO87_PHO90_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000002">
        <property type="entry name" value="Fumarate hydratase class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008909">
        <property type="entry name" value="PRK12273.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF1">
        <property type="entry name" value="FUMARATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="457"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="496"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="539"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="683"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="721"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="766"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="12">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="110"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="569"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3215380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1301" mass="143261" checksum="922D612A33267161" modified="2024-05-29" version="1">MKFSHSIQLNANPDWIDYYLSYSNLKKLIYVIEKNTLGITTDEEVSVNLDLDHSDAPKGTTAHFVVALDEQLLKITEFYKKTEHTLFLKVEQFLTELNFAESYETAHIYSPTTTSPNDASSGKINSPTSPNQTTVSISEDRGSSNFAENSSIAWSSKNMKLRRKQLANTCVELYVLLCNLRNYVDLNFTGFSKILKKFDKVTGSKLKRTYLEKVEEQYPFFPSTRDALNDKINKIAKGYSRMACDGRIELAFHDLDSHLREQIEWERNTIWRDMIEQERRTNFVSLGSAKPRGGDQSNITTDKTINVCGNKLNLPWFFTFSNVIMLFSLGIFFRLIIYPVFESVEQSYCFAILIFASMLWAFELVPLFVTSILIPLLVVVLRVLRAPSQIPHSGEEIYYRLTAKEAAKKICSEMFSPVIMLLLGGFTLAAALSKHNIAKEMASFVLAKAGSQPHRVLLANMFVSTFASMWISNVAAPVLCFELVKPILRNLPHKSPYAKCLILGIAMAANVGGMASPIASPQNIIAVGYMDPSPSWPDWFLISLPVCLMIDIFIWIILLVLFHPTESTTPPELFQRRSNRDNNNENTMHSNVNESTPLINGRGRTRSLPRSFTAVFNTDSDGQTRHWNKKQYFILIITFATILLWCFESALEKHVGDMGILAILPMVAFFGTGILTKEDFNNFLWTVIMLAMGGISLGKAVESSGLLKEITNNLNPMLEGLAPFKCLLIITCVVAVATTFISHTVGALIILPVVKQIGESLPSPLSRTLVMGAALMCSGAMGLPVSSFPNMNAISQEDPTGQPWLKVSDFLKVGLISTLIAFLSTSNVRNFSGSLKSLQSFRKERDTFGELSVPSEKYWGCQTQRSLQNFKIGGHTERMPEPVIEAFGLVKKACAIVNVKNGMDKKIGDAIIQAADEVASGSLKEHFPLVVWQTGSGTQTNMNTNEVISNRAIEILGGELGSKSPVHPNDHVNKGQSSNDTFPTAMHVAAVSEINKKLIPSLELLHKSLKNKSEQFSSIIKIGRTHLQDATPLTLGQEFSGYATQVEYGIERVKDVLPRLCYLAQGGTAVGTGLNAAKGWDVDVAATLAKLTGFPFKTAPNKFEALAAHDAIVEASGALNTLAVSLNKIANDIRLLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQSEALTMVCAQVVGNHSAITFAGAQGHFELNVFKPVLIKNLLNSIRLISDAAASFTNNCVVGIVPNEKKIASILQESLMLVTALNPYIGYDNAAKAAKKAHKEGTTLKEATIKLGLLTPEEFDRYVRPEQMIGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1J0</accession>
    <name>A0AAD5U1J0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="18">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">HK099_003538</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 18">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 18">Membrane</location>
            <topology evidence="1 18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="18"/>
    <dbReference type="EMBL" id="JADGJW010000231">
        <property type="protein sequence ID" value="KAJ3221416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1J0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000021">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000064">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 17 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 18" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="917"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="966"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1008"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1047"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1074"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="62"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="19">
        <location>
            <begin position="157"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="886"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="15">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="558"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="581"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="614"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="694"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="695"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="696"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="833"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="839"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="860"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="863"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="864"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="864"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAJ3221416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1172" mass="132751" checksum="34E20987283C4DD4" modified="2024-05-29" version="1">MFTKKKNERTLKNSSLENSFELNFNKSSIIPNNQTSQKRTSSINSQSRIFEDEDDTSVHRIIYINDCIKNQQAKFLHNSITTAKYNFFTFLPKFLIDQFSKYANLFFLFTACIQQIPEVSPTNRFGTVVPLSMVLLASAVKELIEDAKRHTQDKTINQKKVKALAGNGGFVSKLWKDVVVGDIVRIENGEFFPADLILLSSSEPEALCYIETSNLDGETNLKIRQGLPETMHILTPEEAVNFEGIIKSELPNNSLYTYEGTLRYNHKELALDPISLLLRGAVLRNTRWVYGVVVFTGHETKLMKNATKTPIKRTKVENVVNTQIIFLFCILLSMALCCALVTLVRSSQTGNFEEIILKQSGSLVALEAFPLIVTMEFVKFFLGTMINSDLDMYYEESDTPATARTSSLVEELGQVDYIFSDKTGTLTCNIMDYRMCCVAGSGFAQVVPDDKKIRVDESGKEIGYHDFEAMKRALKDSKSVLGDNLREFYTLLAVCHTVIPETNESGDITYQASSPDEAALVKGAVSAGYIFTTRKPKSVTIHINGIEEEFEILNICEFNSTRKRMSAVVRLPDGTIKLYIKGADTVILERLSQNNPYVDSTCVYLEEYATEGLRTLCLAVRTISEEEYSKWSVIYEKAATTINNRGDALDAAAELIEKDLMLLGATAIEDKLQDGVPETIATLALAGIKIWVLTGDRQETAINIGFSCKLITEEMSMIVCNETTHHETKKFLMDKLELVKYGTTNLDSIPDTKINYNDSIDEEYDERSPTFFQKLKGKLFKKKKKLFNKDIAVDNEPLALIIDGKSLSYALEPDVALIFLELATHCKAVICCRVSPLQKALVVKLVKKNVEESVTLAIGDGANDVSMIQAAHVGVGISGQEGLQAARSADFAIAQFRFLKKLLLVHGNWAYSRLSKLILYSFYKNITLYLIQMWFALDNGFSGQVMITQTLILTLFETWTVSAYNIAFAVFQPVAIGLFDTYVSARMLDRYPQLYRQGQKSLFYNNKVFWYWLFNCFFHSMILYQLMKFAYGEGTILADGRLADNWLMGETVYTMVLITITWKAAIVVDVFVKFTYVAIFGSIALWFVLFPIYATVAPMRNYRPHSYHIIQEIQKFNIPDYRPRMEWFRKAVHKVRQIQRLKRNRGFAFSQNESGQAELIRVYDTTKRKPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U277</accession>
    <name>A0AAD5U277_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002975</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000202">
        <property type="protein sequence ID" value="KAJ3221907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U277"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="288"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="288"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="496"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="735" mass="81707" checksum="1A4846D1EC9AE9BA" modified="2024-05-29" version="1">MDALYQKFYKTFTLSTQKFDKWYHFQKQDVLDQRTTHRKKLNELTEKIALVKEQNLQYKENELRLAEAEEKRKKETEYQKAELQKILDENSTLMEKKKKLEEEIKLCRQDFEKRSEALLESKGNYQEQLKKNEPELKIFEDKLAWKIKTIKISSAAIKIDNHDSLHYNEILSKKNFYRRQSEGDLSASLLEFNNVNESEDDNSSTGKQQDDVLITLLGDTKLSTKSVDINSVHSMKQSSDTNIKATLPMHSSTKSSLLETTKVSNIGGDERQALSSVTFNLPSASASASASSSASSSASTSVPSSASSSAPSSASSASEISPSDIPNQLPDLSITKTSQIQRKHIAPKTVPAETNIFSVNDSFTQNDNDAASIKTTFSRISTPQPSTSAISNAATKIEPSPTPNLLGSGVIIQTTSVESNLAALLQNAPLNNMVADTPFITFNADKETSSLASEFPTPTDSILPTPDFDISANTFSPNVMPMDTENKPDIPKDTEQQQTSKGQSSLLESTGSKVLLGSVTGSVVVVGAIIGSILISKKKRRKNNILKYNDSSRRGSPDSFNEKYFQDQPKPNLSENASLHISQLTFATNNSREVFRSNVNSNNNYFNNSKYTIDSFQKPTLVTLDRKLTLIPENTVESGHFAIDFTTMPRDKSSAIEIDEKYKSIYSSRTKKSNSYSFSVAGSDLQSFSSGSERIESVYSVETFSSYDDGKRESTYSEYNMPINYDSVNYNAFHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U297</accession>
    <name>A0AAD5U297_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SRP1_2</name>
        <name evidence="10" type="ORF">HK099_004125</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000284">
        <property type="protein sequence ID" value="KAJ3220645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U297"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000021">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.690">
        <property type="entry name" value="Importin-alpha, importin-beta-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036975">
        <property type="entry name" value="Importin-a_IBB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="9">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="113"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="325"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="532" mass="59057" checksum="0FA2F5B549CF8854" modified="2024-05-29" version="1">MTSRLSNFKNRGDMQQDELRRRREDAAVEIRKQKRLESLAKRRNIPLGSENQSESEDEQPKSSQSNQISAQLPEMVAGVFSANEALQLESTSKFRKLLSKERNPPIDEVIHCNVIPRFIEFLYSTNSTLQFEAAWALTNIASGSPQQTQVVIDSGAVPVFIQLLSSPAMDVKEQAVWALGNIAGDSPRCRDYVLKEGALKPLLGILNESQNNLSMLRNATWTLSNFCRGKNPQPEWSLISPSLPVLAKLIYAHDEEVLTDACWAISYLSDGSNEKIQAVIESGICRRLVELLLHPSYHVQTPSLRSIGNIVTGDDVQTQVVINSGVLNALLSLLNSPKDTIRKEACWTISNITAGNAQQIQCVIDANLITPLIDILNRGDFKTKREACWAISNATAGSVQQNPDIIKFLVNQGCIKPLCDLLTSGDARVIQVALDGLENILRVGETERHLTNQNQMSVYIEVADGVDKINQLQMHDNQDIYKKAYNIVDTYFSNDDEDDDLVPEVNAEGAFTFKEDANLNGDIPQGGFNFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Q1</accession>
    <name>A0AAD5U2Q1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002363</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000178">
        <property type="protein sequence ID" value="KAJ3222375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Q1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="9"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="491" mass="53951" checksum="D0CD685531EFE794" modified="2024-05-29" version="1">MGNFFNYIIAFASAIGGLLFGYEIGLIDQVLGMQNFAITFGIKHYNEAGLLVDTEQAKDIKGNVTFTFLLGCTVGAVIVSIMADILGRKRSILVGGFAFAVGGLLQALTGSIELFYFGRVVSGLGIGVLSMCVPLYISETAPTAVRGRMITVQQLMITIGILLAALVNLAIRNSQEQVNATEKQGSEPEWRIALGMQVVPGVILVFLMFFMPYSPRWLEDRNRHAEAVNALSKIRSADENSAAIQAEYKEIKEGVEFERSIGNATWSELLKPGIINRVLIGVTLQFFQQWTGINVILYYASDLFTAMGFPYETASKSLNIVNSFVNVVGTLPGMYLIERIGRRKLLIFGGLGMSLSHYLVCLFIGLSKTGNASLNLGALIFVYVFILCFSSTWGPVVWVYQSEIFPLRIRAKGTGIATFSNWSMNAVIAKVTPIIIDAISFKFYLIFGSTCLVMSLFCVSFVPETMGKSLEEMDELFGKVNVHEVESQKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U357</accession>
    <name>A0AAD5U357_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Actin-related protein 2/3 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SOP2</name>
        <name evidence="9" type="ORF">HK099_002113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Cytoskeleton</location>
            <location evidence="7">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000168">
        <property type="protein sequence ID" value="KAJ3222601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U357"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038093">
        <property type="entry name" value="ARP2/3_su1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="52"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR038093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="382" mass="42494" checksum="678D637FC36B300D" modified="2024-05-29" version="1">MTYSEAHQLFWDKPLFTHSFNKDRSYLAVSPNSNEVHIFKKSGTNWEFVYNLAEHDKLVTGIDWAPNSNRIVTCSQDRNAYVWSFDGQSWKPELVMLRINRAATCVKWSPNETKFAVGTGAKVICICSFSEADNWWGSKHLKKPLKSTILCLDWHPDNILLAAGSTDKKVRVFSAFIKGLDEPTKNAVWGEKLPFEKLCGEFGTESTGWIHSVAFSPSGNQIAFTGHDSTFTVVSPGQSVNSTVKGSMLPLTSVMFVSENQAIGKLDRPFRKLIFIGVGHDCRPYLFSFTGSQWQLTHNLDEGKKKSFGGNSAMDKFRQMDSRNQQAGTDTELSTVHQNTITCVRAFAGNPSQVTKISTSGIDGRIVLWDLLAAGVSGMSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3R3</accession>
    <name>A0AAD5U3R3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000205">
        <property type="protein sequence ID" value="KAJ3221854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3R3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="171" mass="18867" checksum="BEBAEBD81C2E2134" modified="2024-05-29" version="1">MVPQNSKLIRRDFNITIPESINIPTVWLIVICVILFLMFSGVIKCCGCVSRRFKSPQSFGTQQFPVQKSTPKSTPSSKIDNNSNKTVVQPDFSTNNTENANSNFDVSGTSNFPAIAPIQPLAPIVPISKIDNTSASTVRNYTTSVYNAPSTVRTPQNDELSEYVRIAYDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3W6</accession>
    <name>A0AAD5U3W6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SF3 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000292">
        <property type="protein sequence ID" value="KAJ3220550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3W6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051620">
        <property type="entry name" value="ORF904-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372">
        <property type="entry name" value="ATP BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372:SF2">
        <property type="entry name" value="SF3 HELICASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="30889" checksum="A5A640DC99599711" modified="2024-05-29" version="1">MIIQTKKTNPAQMPGSESDCDPWAIEEVDKFLEKVLPNEQVKNYALKKFSSCLNGNLPNTNFIFFQGGGANGKSQLLNLMAKSMGGFGTKIDSTLITRRRSDANSAIKELTGQEGTIDARNLNEGIVEFKMQAKLFLATNFLPNVDGDDNGILLFLLLSKLMLLISRLLVGSVNNIRMSLIFALLLIGLVNVLQLKRLRVVKFHSVFKENANTDNRFEFERTAFMNILLTFYYKEIFDPPEVIANTEEYREENNELEVWAKENIVYKARSMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Z4</accession>
    <name>A0AAD5U3Z4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosome biosynthesis protein rrb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RRB1</name>
        <name evidence="6" type="ORF">HK099_003020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000204">
        <property type="protein sequence ID" value="KAJ3221874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Z4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051972">
        <property type="entry name" value="Glutamate-rich_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903:SF1">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="5">
        <location>
            <begin position="96"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="342"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="392"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="491" mass="55958" checksum="34E524D9CA1364CF" modified="2024-05-29" version="1">MNKRKNLNQVEKVDAKKNVKSNKSKEKIENEENVSDLEYEDVYEDEIEEEVVVEQKDEEEEIGEDDLMEDIDDNDDENEENVKVYLPGQEIEPEHVLLPDNSAYLMLHQMGVEWPCLSFDIIKDKLGLNRTQFPATSYIVSGSQAPNPNENKIYVMKMSQLHKTKNDDLDEDMIEEDDDENDLDEDPILEHREIPHYCGVNRIRLMEHPEQQICATWSEEGRVNIYDITQHVLSLDTPGLIPDSNLLPLHAITNHNRIEGYAMDWSTKVTGRIVTGDCKGKIYITSKNQSGFQTDSQPYKGHNGSCEDLQWSPTEKDVFASCGVDGTVKIWDVRMKQSALSIKAHNCDVNVIAWNKKVDYLLASGSDNGIFSVWDLRTFGKGQETATSAATFNWHKKAITSIEWHPFETSMLACSGADDQLTLWDLSLEADLEEQQVMEEKDGRKIEVPAQLLFIHQGQSNIKELHFHEQIPGCIISTSSDGFNIFKTINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4D6</accession>
    <name>A0AAD5U4D6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000565</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000113">
        <property type="protein sequence ID" value="KAJ3223904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4D6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF7">
        <property type="entry name" value="FUNGAL TRANSCRIPTIONAL REGULATORY PROTEIN, N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="667" mass="75881" checksum="A72555CE05A45BFD" modified="2024-05-29" version="1">MHGFSGNACLHCKKKKRKCSLDFPCARCIKDGVECVEQKVKPRGKRIKSPSLQTVNQNETNKTVTYDPGTLHNQERRCSSNLSSSSSSDSVSSTEEVSSSSVSPVFSDLVPSSSSSSNTSQIFNLFDFSGVFNNPIPNPERNHSFIKEFSTEESLMIFLNEEIPIEPTQETKKTLSLIPKSYSKLKNHFIKQSLLPLYFVIFSSVFISGGIQFLEPQRIGVQKNSNFRPRKLDESLKEFNLSKATDLNFILLQLNSYKDSPSEFLIYLSWCCLSCRHPVLFTKEFCGSPQKASIMFLEEGIRHLKNFTSISEISLAITYAIPIFFCYGDKSKGLVLLYKLYEIAVKADFDKTTGDNCIEFVLDPVNMYIRKLNWVNLLCLSTFASYPCLGNELDNMEMLEESEWNIFFDIKVIGKFQGAFNITTYTQICFLVRRALNFSNCNDVTKIGEKLSVATILNRDFIVWLESIPLESKLFSSLAEFIVSVKKIALDWRLVINNAKVYMWWIFGIIKTHFSSIKYNKYYKFLLNSGTSPIKATSMDIILCGIRALSSILSVFPPEETISEFKTNYNGGKRFSFGPEVIFYYSTILKEVTLMSLSALDLCEGWAAINEIREEVLKFHLKSVFLTVLKSFNTPYSTECLQSVEIKVNNYLGILEINNLYITHSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4X4</accession>
    <name>A0AAD5U4X4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_001605</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000147">
        <property type="protein sequence ID" value="KAJ3223030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18597">
        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18606">
        <property type="entry name" value="ABC_6TM_YOR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="742"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="785"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="868"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="971"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="112"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="450"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="743"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1060"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="437"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1309" mass="146016" checksum="BD486403235961A2" modified="2024-05-29" version="1">MNKEKSANSKPSIDHEILNSSKNNPVDSANIFSVLSYSYLDSVFWKGYRNPLEVDDLYKTPKTLTSVYNVNAFEVEWEKELKKGNLDPSYTPNLSTAVTKLVFWKLLPIGMLKVLGDTAVVLSPLVLSSLIKYIALSENNRNTPVYEGILYVLAMFLLSIFNTVLINYYFQTAQYIGTQTQTALSTAIYKKSLRLSAASRQDFNAGKVTTVVSTDCFRIQLNLMFINVLWTAPIQILLILIMMVISIGPAAIAGVGLLILLTPVQTVLYKKLSLIRKVVAPITDERVKLTQEILSGIRIIKFFSWETSFLKKLQTIRELELKQIFRRGVLTAIVVAIVFGIPVFCSTLSFTIYGITRELKAQDIFPTLTWFGQLRFPLMFLPNVLVGIAEYRVAIERIQKLLLAPELESQPEKVVDSTYSVQIENGEFLWESPPPDIVKDDEKNSKKNSEKVEEIVPTTHIPTESTLKNINIKIPHGSLVAIVGKVGSGKSSLLNALIGEMKKVNGSIKISGSMGYAPQQAWIQNASLQNNILFGQNMDRNRYVSTLRDCALERDLEVLPNGDQTEIGEKGINLSGGQKQRVNLARCVYYNSDVVLMDDPLSAVDAHVGKALFENCILTALKGKTRLLVTHQLHFLPKVDYVIVMKDGAISETGSYAELIESQGEFSKLMSSYGGVEEEESAEADNDVDHKENMAANDRIDATVVKNIQNPAKALMSTEERNVGRVTGATWFAYIKNSGGPLLVFIYLLNLIINQGTALANNYWLVVWESEQIPGWSQVQYIGVFWIWGVAQTISLFFLVLTFAFASLYASRNLHNNAASRILRAPVLFFDTTPLGRIINRFSKDLDAIDTNLAEAIRMFTMTFAASISSFVLIVYATPLFGIIILPLLIIYYFMQSIYRTTGREIKRLDSVSRSPLYSHFGETLQGLSTIRAYNEQEKFISVLHNRLDATNQPYFILIAAQRWLGLRLEALGALVVFFAGIFGVLARHSISPSILGLSLSYAIQITGILSWCVRQFAETEIAMNAVERINYYGTEIDMEADPIIENSRPPPNWPSTGVIKFENLDVKYSKEHPLVLKNVDFTIGDKEKIGVIGRTGSGKSTMMNALFRIMEPSNGSIVVDGVNIRNIGLADLRKGLAIIPQDPMLFSGTFRSNLDPFGEHSDNELWDALERSNMKAKVLESEGSLDAPILEGGENLSVGQRQLLCLGRAMLKKPRILVMDEATANVDYETDSIIQRSLREDFKDATILTIAHRLNTIIDYDKVLVLDNGVIVEIGTPKDLLNMENGKFKSMVDETGSANSELLKSLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U505</accession>
    <name>A0AAD5U505_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NIPSNAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NipSnap family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000089">
        <property type="protein sequence ID" value="KAJ3224564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U505"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051557">
        <property type="entry name" value="NipSnap_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017">
        <property type="entry name" value="NIPSNAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017:SF17">
        <property type="entry name" value="PROTEIN NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="2">
        <location>
            <begin position="102"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="NIPSNAP" evidence="2">
        <location>
            <begin position="189"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="271" mass="31947" checksum="E0DCBACF443E6966" modified="2024-05-29" version="1">MIKNFNRKYSSALVKSFTSLNSFRSNRYFSVSSEVSNEEKGKVKTFVKSILHGNEAIKADLSSTYSKTLDRGKYVHEKQVHLVKPEAWDDYQGLVATHYKRMNEMEEFKVKLFGSWDVEIGESLDQAVHIWEYNNYPGYISTHDLLKKDEKYQQFLKELRPMLRSRSNQMLLEFSFWDSKISQKPNGIYELRTYVLKPGMLLEWEHEWQRGLEARRQFVQPIGAWFSQIGHLNVVHHMWADLQVRKKMREAAWQVDGWAQTVVNTGIIRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U530</accession>
    <name>A0AAD5U530_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004445</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000313">
        <property type="protein sequence ID" value="KAJ3220139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U530"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF27">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE FAMILY MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="497"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="5">
        <location>
            <begin position="435"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="5">
        <location>
            <begin position="520"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3220139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="688" mass="77970" checksum="3E0A62495F5FC6AF" modified="2024-05-29" version="1">MTFLDSCISCSNSNTEKGVHPLNFDDNPIVPIAEFVTNATRNFCKVSHDGKFVAFLAKGQSKNKTLQVEIQPLHAYLQGSNEGHKVVVTHPTHDIRGFTWSQSTSNYILYWQDKNGNENMQLFRTNIHTLETICLTPFEDVKLGLVIDNFYIYQSKIKPNKCLVALNINDKSFFDIYHLDIESGEIEIYLKNPDKASLFYCNDNLDVQIYCKLAEDGSTEVYYNEISSGEWKNIIKVEATDTVSIVSLTSDGKSLIYRCSTNEACTVLLQYDFKSNSQQVLSRGSVDVASVKVNPKTNLVEAVCYDSGRRNWVILDKEVKADFDILVGLDEQADIEIYYQTKDNNFWVIQTFFGNKPTCYYLYERESKKLSKLFATHPNLEKYKFGKCESVNFTARDGLQLQGYFTYPSNFSPDLKYPMVLLVHGGPWSRDRYGFGLVAHWLANRGYVIFQPNFRGSTGFTKELLVKGYKQWGKTMQTDLMDAVDMAVSKNFIDRDYIAIFGGSYGLIISYLFSHLILIGGYAALAGVALTPEFFTCSVDIVGPSNIHTLLNSLPPYWEPEKRKFRVRIGDLEKESEMLKEVSPLYHAEKIVRPLLIGQGKNDPRVKTAESEQIVDAIEQNGGNVYYVLYPNEGHGFSSPVNRIDFYSKTELFLSKFMGPKTRIQQGLSLDVNVEGSSAIVKIIGKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5L9</accession>
    <name>A0AAD5U5L9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000070">
        <property type="protein sequence ID" value="KAJ3225124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5L9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070646">
        <property type="term" value="P:protein modification by small protein removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013535">
        <property type="entry name" value="PUL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF7">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08324">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51396">
        <property type="entry name" value="PUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="6">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="146"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="PUL" evidence="5">
        <location>
            <begin position="285"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="66556" checksum="6CF06FEE88A92BD5" modified="2024-05-29" version="1">MAKVLSKQLTGMQINGIWHTSVVCFGKEVFFGQGIQQCPPGRSGHGQPIEIIDMGETELTTDVYNDFLNEINGFWSADKYHLLDNNCNTFSNEVCNFLVGKNIPDYIVGLPAEVMNTPFGAAIRPMIEGMFGPSSHPQLNLNGFQLTPTTSANTLEPTAISGKIYSVKSLTEFQNLLKTHKCVAVDFTSNNCPPCRVISPYFEELVMEKSKLVGVSVEVPVSREISTFYNITATPTFKFFLNGELLLEFKGANRQELKSAIDFLIYSGYPPHPHSLINTSVLDSFFSPSCSPIKFKNFSNLDQIFLKIAELLNRSETLKQEKLNFDILKKKLKQQFELNQDVFFKNESNFKQFDDSFQKVLIFFVQNNQLNDIFPFVDVIRLLMLNKDIQEFYMTERVPFPILLINEVINFEQRGKALMLMTNRLACNLFYSEQSIKHILFSENRNVDNTKTSFKSIVTSLLIESLLSKEKIVREAASSLSFNFCFSFFKYFSEEEKKNFEMEEVKTELICCFIKSFEEKFEKESFERLLVSLGILIKFCEKEVLELISELGLKELLGKVDMVLLSEVRVQKLINEVKQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5T9</accession>
    <name>A0AAD5U5T9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RPL37A</name>
        <name evidence="10" type="ORF">HK099_006863</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000062">
        <property type="protein sequence ID" value="KAJ3225405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5T9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000001">
        <property type="entry name" value="Ribosomal protein L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3225405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="92" mass="10405" checksum="CA09A203C5CBF04B" modified="2024-05-29" version="1">MTKGTCSFGKRHVKTHTLCKRCGRRSFHNQKKTCAQCGYPAAKLRSFNWSVKGKRRKTTGTGRMAHLKNMPRRFKNGFREGTSAKKVTAASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5W0</accession>
    <name>A0AAD5U5W0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="10">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_003732</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
            <location evidence="10">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="10"/>
    <dbReference type="EMBL" id="JADGJW010000249">
        <property type="protein sequence ID" value="KAJ3221136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5W0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000828">
        <property type="term" value="F:inositol hexakisphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000036">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040557">
        <property type="entry name" value="VIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18086">
        <property type="entry name" value="PPIP5K2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VIP1 N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp fold RimK-type" evidence="11">
        <location>
            <begin position="235"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3221136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="974" mass="111636" checksum="95AC361F40B029E1" modified="2024-05-29" version="1">MEDYKKEKGVCAKDNKARSKPMRNILTRLLNLDLFEAVIFGDKVIDEEDIEKWPTCDVLISFFSKEVFDNIPFNYCNYCNKGTGFPLKKAMDYVKLRKPYCVNKVGLQELLLDRRFVLRILDKIGVPTPNRIIRQKAYDKPIVSEEVVREIKLALNIDISPESFPEHNVVQLDSETIMCEGRILKKPFVEKPISGEDHNINIYYSAEMGGGGRKLFRKIGNKSSEYSKDLVNIRMDASYIYEEFMMVDNAEDVKVYTIGKDYAHAETRKSPVVDGIVKRNADGKEIRYVTPLSEAEQAMARKITLAFGQNVCGFDLLRANGGSFVIDVNGWSFVKGNTDYYTKCSEILGKLFLEEVEKRNKFPFLKRLTTEKKIEGPWKLKAFLSVLRHADRTPKQKMKFNFKSQTFIELLNGGQEEVVLKKKPELELIVGACKKARTENKENQESVSSCLRIMQLKMDLPGTKVQIKPIFKKADDSETTAKQNIKPNLVKVQLVLKWGGNFTHGGKFHSQDLGENLRKDLLIINKDLLTNIEVYSSSEQRVTDTAEYFSKALLELEELPLNFLNISKEMLDDSNAAKEQVDLVKKKLQILLSPVGMNTISESQLTSPSEGNAFPLEIPSLQQSLNNANNNFNEIMNQNVSNAFNNNSPYLFPDNLSSAASSVLDPSERLQMQSLSLDFHPASYIVEDLIDILRNLRFIMRDNFKKLDVEKIQTFWCCHEDPFLFKERWEKLFKDFCDVKREAFEASKVSELYDSLKYDLLHNRKFIDKIFYSDKEYVNSLYFKSKALFDFVGPKEYGIEEKEKFEICLLSSSVLVNKLVEDLKTAASEETPRTRLFFTKESKVICLLNFVLLSGLNAKLPVSKSQSRSDLDGIVSHILSSSGFNPLPDTEMAELDYLTQITFELYERGGNDNLANEYSLRIGFSPGAHDYNLIDMQMDERHALGVKPRKWITEYIPLHEAIRCLSQRNSPAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U601</accession>
    <name>A0AAD5U601_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cleavage stimulation factor subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CSTF2</name>
        <name evidence="3" type="ORF">HK099_006400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000055">
        <property type="protein sequence ID" value="KAJ3225679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U601"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="15"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="70" mass="7934" checksum="2BB2D83211FE6B16" modified="2024-05-29" version="1">MSHQTLGSGKKPPSKVVFIGNIPYDFTEPQLLEIFREAGPVINLRLIFDKDTNKPRGYGFCTYQGDFINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U638</accession>
    <name>A0AAD5U638_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DDHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008576</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000096">
        <property type="protein sequence ID" value="KAJ3224332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U638"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055555">
        <property type="entry name" value="PA-PLA1_DUF7131"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057826">
        <property type="entry name" value="WWE_C20G8.02"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF10">
        <property type="entry name" value="LD21067P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23465">
        <property type="entry name" value="DUF7131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23463">
        <property type="entry name" value="WWE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C20G8.02-like WWE" evidence="2">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7131" evidence="3">
        <location>
            <begin position="195"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="54284" checksum="D79DD6039D5E0B13" modified="2024-05-29" version="1">MSSTLEEEESELIKEPKAQWFFGDVIKRDSREYKTVPTSTKPTVWTPFTEKDSNEIEKKYISFTKRKIDSSIEKSNFKVAVQEDYLSEVDLETLELYSVYWPGPVYEVRRGFWFCAPDGKTFIPCNENLCRQVEAGFWKYKPWKKDISIPGVPTSFSSSENIDQVPSEEKSKPPSTSSAVNSAVQKHATDKPELRWALFGPYMNQYVIYHSQSVAFLLSDLLSSKIYRGVMETISKGENLGGVRLVRGWDEVNKLKKPIVISPSSSVPTSTSPVRSKEKAEDEQNDKSKIEAPRIRSVEDLNLREEKEVKPTSSDIENVVNDFINSPRPSSNYLLNSESEDRQIDHLIFVIHGIGQKLGERIDSISLVNDCNMLRSTLKSSSKLVRESMVELNVPDGSGVQVLPIQWRQKVQFGTSDKLNKNSKNSDNETDATWSTDAGDVSGSAVKKKPSKVLDEKLERVADTASLENITLDGVPSIRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U647</accession>
    <name>A0AAD5U647_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003543</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000231">
        <property type="protein sequence ID" value="KAJ3221421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U647"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="454"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="504"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="620" mass="72772" checksum="1540D800C53D22AF" modified="2024-05-29" version="1">MTLSSIELISINNKTQNNLSSNRELKKLLKNVQQNSDYPVNTQDERFHSQKDINYFDTHTEEYITKFTGYFKYFPPWVQSLIFVLALLSLTGFYIFIDHGRQSKWFDHSDDTTARINLIPFRNVEITSVSAILLYCFGSSIILNSIGYKFFLNQHDARFDYCGKLVDTTFSLYSRPNSSLANFEYPTPNFWFKDEEQSNATLLTGADPYVGIKNFFRILPYLIIFTSFFTLVISYGNISRQCKNYNFPLHQRYIIRILMSAPIYSVLCLLSLVFYQHFFIWQTLRDFYEAYTVYSFYWLMRYYLGDNEIKQLLSLVSYLDEETKSSLSGFSSLLKSKKKKENLQIYLKERKKFYTIFGGINLFSYNPTVSSFLINTEKYILLFIFWKLITTVSINIMNILNVYCMKFTSIAKLTIFFLKFLGVIATNAVNLLALNGHPCFVGRGLENQHIRAKMWSILFLINSVFYQTVFISIFFTAGFSYYPETLSRIIPATPRWSYVEIQEALNNILIIFEMFWLSIFYSFAFPSYLYQPSSNPLKLRKIGLENKGIDEKYRRNLNQKGNLKGFLAFFEAFHFLSDFLKFIKHTRDFGIAFGKEDNRFHNFEEDASDVSSLNQSSVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2024-10-02" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6A9</accession>
    <name>A0AAD5U6A9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exportin-5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000089">
        <property type="protein sequence ID" value="KAJ3224559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042565">
        <property type="term" value="C:RNA nuclear export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045478">
        <property type="entry name" value="Exportin-5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF3">
        <property type="entry name" value="EXPORTIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19273">
        <property type="entry name" value="Exportin-5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="1">
        <location>
            <begin position="105"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-5 C-terminal" evidence="2">
        <location>
            <begin position="393"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-5 C-terminal" evidence="2">
        <location>
            <begin position="1024"/>
            <end position="1266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1312" mass="149654" checksum="83897EA91425565A" modified="2024-05-29" version="1">MEHELIEAINLIYNPTSHSDQRRAATEFLESIKSLKEAPFLGHKLAHKNNNQQDHIRHYGLSLLENSVKFNWTKFSSEEAEKIKLLIQDLLNEGIKDINEEKLFTKEKLVKVTVEVAKRMWPMQWPDFNYFLKCLYDQNPTTRELSVLILRSLYEDVFLYEDVVAQKRKSELTTALFVISYSYRVLGASTIPSTTVSLELNHSAIYLTPNLDTFLSNAGLAPGTKLLNQNIFSNLIQTNAGDVEGWLSKWTSDLFILHQNWCNEFNAGYGKSAEISELLIVSILSAISVAVHWASLYAIIDTAIVPRLLDLIISPSRKIRLGVTEVLFVLFSRPVSSNQEAYRYDAVLKPIFEVPLPSGNIGLENLILAWAKNHCLVVVDDIDRAEQNAKVSEDDYIVIKRLAQAITALGENYVCHKTTKKIPNLIRFLEEMLVLSDHPSLIVAMQPTNFWTLILRHESLKVSEEVLAVMPPLLELSAKKVSKSEAASKSNLNSNYSNIDFDGHTEQLAFGMLIRQKYLEICKLIAINKPLDSYKWMLSRIEYRFGSIPNPEELTNLTGRNNLNQYFFAYLTFSADGLVTFDTPFYHHFEADVNIMSIVLSVLPYVIPEGNTILKAELFNSVELLLSKVIGFESNDPLLIRTKIDAVTAFSVMIPYDLKMLSPFFAKLFEYVSFHQPFEKSLVTSSSSGWYPQLSIETKIIRKKAAAFFAKMGSTMPNILIKIYDDLSRTVFELVEKDLINYQEQNFLMECLLAIIYFNTALSYEEKIAPFQAIVNVTMRSFEILNNFQIFDLRIPDENLGNVMQEFLGIDFLAKNCNYFTLCGCDSIFLGDALNEKEKCSPLVLESLNRTKATRFQCSKPFFSISQLTTRTLQVKKSEDFNADHELWGDYALRVVPYLIGIIRGLHSLADPAKWESLPPLFYNTLTSVTYMERMLILGRTIDPTENEISKLNETYLEKELKGIKEFLNHARDHSQILPHGISTKSNYSRHFWLCSSYRKQALDIFTKLNSKTVGVKLSGGLVKLDSEWKILMDKGSALDKKGDEFESLIDEMNYLGGDKMEDISDEIFAEKVLRNLTRSVVNFFSLIFDVKKSTGEPPDNYFQHKELAEFFLKSVAIASPLMTFLFHILVYQDSTSSRKSVNICTHLVNLIMPSDENSNCGFNPYHILFGQDLVVSALDCLRDPYHQEVHFEAVNLIGLIYSKLLIVGKIETNDGLERIREIFSGLPGKGIQATVKFENEFVSRETFKEQVMVLREFLADVKGLSVSQRGRKPTSFLLNISEKNLLVRPKIVKSNVLDEEDNSDMMENLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7G0</accession>
    <name>A0AAD5U7G0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002415</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7G0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF7">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="299" mass="33642" checksum="38A8D00EAC095788" modified="2024-05-29" version="1">MESVNLVEASKTLQKKQNETLQDFFSSKKQEKLNKKVVWHEFFNEIPKDITSPSIIIAHEFFDALPIFKFQYTKNGWREILVDIKEEIEDSKNSGEFRFVLAPGETQASISLTDTPRFDAEKKVGNVIEVSAESFDITREIASRINENGGFGLIFDYGKDNVSNDSLRGVSNHKFVSILKEPGSCDITADVDFSLLKSACSHLAFPYGPITQKKFLETMGIYTRLGMLLKKGGLNSSQRKSLVSGVKRLTSLENNVGMGNIYKVLAITNNQLVPYSFDSDETLVNETRQTEGLEEEKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7M8</accession>
    <name>A0AAD5U7M8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">mRNA decay factor PAT1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000115</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000101">
        <property type="protein sequence ID" value="KAJ3224193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7M8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039900">
        <property type="entry name" value="Pat1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019167">
        <property type="entry name" value="PAT1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551:SF0">
        <property type="entry name" value="PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551">
        <property type="entry name" value="TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09770">
        <property type="entry name" value="PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="mRNA decay factor PAT1" evidence="8">
        <location>
            <begin position="1"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="83"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="263"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="451"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="94"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="462"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="799" mass="91913" checksum="AF94B7C6131BB7C9" modified="2024-05-29" version="1">MSFFDFNTALPPENGKEYNDEEEKYGQMDLLMEEKYKYGDELQEEEDEDNNETFGDSNNHMIDEEFDFTQAGNAFFQLEEKQIKRSPPPKKENPSSWNQSTSQFHAKQQNQYQLPQQYGQEQQQHIVSVRKKNSIQDIWKKNPQMGSQNYQMPTLQAQMKQQFQSHQQHQPHFQQQQQNMIRQQYQMQQTHSKHISNQVQQQRQHQQTMSVEELESQLLYSRKPGGPENAMSLEEVEAAMLSKRQLKFQHEVDMEILKQQRLRQQQQREYTTGRLTPPTDFGSPKQVKSAYQSENNTRQFERDRQYSNDRQQRPSNFNSMRSLSHGMGRKEGQIMNQFEKELIAKIQISQLVSQDPYTDDFYYVVYSGLKNPQHHQEVGQQKVSSNSFDKNLNWQQNMLLNNNGAKVSLENAIKTQMQRLIDGRKQQKPKGTSLSLEGALGKIALNSTKTPKKQMEVKLSDKLSNLDSKSSGKKSVSASNTIVSKKNVLKNIESVFTAVLNLEHLKRKLSGEALDLSSEMDEETKQGKWNKEYEENVDALVTNLHFTEAISLDTPHPLTHFIHYAKGKKIIPRAVRYLTPELTLRFLSTLLSRFEGLDVCHIPIGILNEEVELFMMTVIPPFVQVISEVNLAVVNNFMRILLERHPTQWLTKSKIGLATLTMLLSRAEILKQTYPNGGVGVLEVNSWTELYNFLFNSLQNNFLGIFPSFSKLLKTAKVTPTQLAQSVDQDEVYVWQFLAALAVGATIPDHQRILVIEVREKVVECSKQEGNVKALGNVNLFLNALGLGIDAAQLAAQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7R9</accession>
    <name>A0AAD5U7R9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phorbol-ester/DAG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001624</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000148">
        <property type="protein sequence ID" value="KAJ3223008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7R9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="560"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="4">
        <location>
            <begin position="703"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3223008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="758" mass="85753" checksum="7F422E8402B6EAA2" modified="2024-05-29" version="1">MFDSNCLLCNGIQISELDLKILNLNYLRAEKENNFTLELIESLMLPLNNIYNNLAFSCPNCSNLETVGLVGETGSGKSSLLNLLLKNKLVGEVDLLGFNVLSCSNGVKTGGGAEAITLLPKFYPYEGLIFVDFPGLNDTRGPYIELLIHLFYKLLILKRKFKFIVVQSYLALSERTSLKKFASLVNCSFLHASNSVVVYTKISSEDGSKKKNSANSVLKNLGDNLFEGSKLNIASFYMPSPDKRAQLSLGVDYTKKYSSRRKEILSSVETLQSKAVIFEKEYSKSVEQLLSKMSKILIALIKSEFTIVLANTLEKFAIKPYDVNPLKSLFNENNKYPLRQIISRLETVQILTTQEHFNESFLNLLTYLDLLDFFQSTTTKKSLRNWTIDDTILNFLQRLENYHSPIYELSSLRLPQKLLEWIKLCEEHYLDFKSFEVKTLYELNILRVHENKFQEVYNEILKVCNFRIVVCGKLLNLWRELAKELQDLCESDEGGTKKKKDPVKIFSDSINLKDGLDLLRFGLGGILPEATRNGLLGGLLVGGTGGLLDGLPSSSVAVTVVGPVGIGLVAVGGLIIVASIMQSIFQMHLESKSRKPIAALGMDFSPFILEIQCWEEIKSVIKDVEKNSISENIANIEEKFLNIERSFKNFIQNSLKNSIEVNEKSKGAPEFKLVICTVIEMYSRIELKMDLIKQSSIGLHFKQHNFVYRSFKNLKWCEVCSSRMFGLYCENCGKHVHVDCQVSMYSRECSRRDFGVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Z5</accession>
    <name>A0AAD5U7Z5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_004794</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000035">
        <property type="protein sequence ID" value="KAJ3226484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Z5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11054">
        <property type="entry name" value="CYP24A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050479">
        <property type="entry name" value="CYP11_CYP27_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002167">
        <property type="entry name" value="GDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279:SF120">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00928">
        <property type="entry name" value="GRAVESDC"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="15 16 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="16">
        <location>
            <begin position="17"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="16">
        <location>
            <begin position="130"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="16">
        <location>
            <begin position="273"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3226484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="20">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="869" mass="98916" checksum="922B90B6820C2A50" modified="2024-05-29" version="1">MTLNSSLNHDKKKQSFNYWFKSFIAGGVAGCCAKTVIAPLDRVKILFQTGQPKFQKFSGHFFGVFSAAYNIKNEFGIRGLFQGILNSNKILFTVYVGHSATLLRIFPYAAVKYMSYEQYKSWLMPSAESETAFRRTLAGSLAGVTSLFISYPFDLLRVRLAFDINIDSKNGVSVTKTFLDIFNEPSPFFRSENQNAIFKFFSGMSNFYRGFCPTVYGMIPYAGVSFLTYETLKNSLLNNEKLKFLLNEQHQKVNNKDTKLDDILNKKSHKTQLGVLGTFFAGSVAGICAQSVSYPLEIVRRNMQIGGLQNKNSLDKKPFHLNTFQTIQLIYKNKGVRGFFVGLTIGYIKVVPMFAVSFYTYEWMKNFTTAVDEGYKILPFESIPKLPSDAQNTSIEYFMKEGGFVKMAQTFQKQHQKFGPIFRYSFFPGGPDNVSVADPTAVSEIYRREAEGEVPARIISQGFAKYRDYRKLPQSLANTNDYEEWRVQRKIINETLFKPEVVFTCYKKKNPDVARTYVPRLDFIAKDFVSRVLGRNPETDPDYANNINRDITGVSLEFIGSIVFGKRLGAFTGEASIEIDEKQQRFIDAVNGIFTTSGTLLSYPENFPAEIFYELPAFKELVKHSDYMMEYAGDLIESKHKNKESKGGLFEFYLNKNEVSSELAKLMAIDIFGAGVDTTSRLVNWFLHALASGSKSIQERLREEVISIAGKEGPIDAKMLSKMKFLKDCLKEVHRVMPIVHANSRINLKDLNILGYNIPSGTPLFMSNYTMSRDSKLFKNPEEFNPFRWSKADKLDPSIPNKSFSSLPFGHGQRMCPGRRVAENEVQLLISNLIRNCEVYYPKGARHPEPVFNLFMICDINPDFRFKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9K9</accession>
    <name>A0AAD5U9K9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methylmalonic aciduria and homocystinuria type D protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9K9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009235">
        <property type="term" value="P:cobalamin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019362">
        <property type="entry name" value="MMADHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13192:SF3">
        <property type="entry name" value="COBALAMIN TRAFFICKING PROTEIN CBLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13192">
        <property type="entry name" value="MY011 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10229">
        <property type="entry name" value="MMADHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3228456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="27099" checksum="40805F12C04843D6" modified="2024-05-29" version="1">MEILHSNKNLLNNLNSVKDVTPYRNQQRQCQQQNRTQVCQKEQQNQNNSKNVVSISKRPEVLSPPKVINYTKENYNNINLNFQFSIHRPGKFLNRDLKLIFPNIGEEVLSNLKILPIFFKASVDLVAVNERSNLERNFFLEEILAIAAKLKKVLNNYFLDLTDPASGYPVYSDRGCSLYPDVDGSVRLLKYDCIQAGCCRVIVHPQWGTKNYPCSIFTDAPVDVIFNIFDNFHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAR6</accession>
    <name>A0AAD5UAR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031942">
        <property type="term" value="C:i-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040201">
        <property type="entry name" value="Mrg3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28142:SF1">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE I-AAA PROTEASE SUPERCOMPLEX SUBUNIT MGR3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="466" mass="52841" checksum="10F9DDBF77C64A2B" modified="2024-05-29" version="1">MQPQIVHLLKYRKFHTIENLKPRGILTKKAFSYQNFSQFSTVIDEEVKKRRRKPFYKRPWIYIAILLCSLPLAYKGLLLYVAWTSFPPSVRVLLRNALASQNNSELEKAEAFLLEAIEESKRVGLSETSDAMNVLIKNWLTLLKFCGKEMASFENLKVEVERGETDKVLRKFGLIHQVITVASKISDVFLRAGNVKAGQLFLEWTTKSLLGWTSDPVELLREVEKTIQDQSRDIETLIDEISLDTSFYSKVPPYLENKEIEGLTSDNFNVLTPGLRMNFLQLSYNFIAKWASPLALGATLEMLAHTFTLQGNYKVGAALYIRALQLVDASKPKSGLTKNSFVATELSVPEVLCRKSILSNNISNCFVELNNFKEAEKWSVKSVEEARLSGENCEICAVIAEFGLAKIYEFMNEKKIALKHFGKARELAIKIGYQQGVDLVKDAILRMKEEEKQSDATVDIGIAKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB75</accession>
    <name>A0AAD5UB75_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed primase/polymerase protein</fullName>
            <ecNumber evidence="3">2.7.7.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002917</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:22509"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate.</text>
            <dbReference type="EC" id="2.7.7.102"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.102" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB75"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044917">
        <property type="entry name" value="PRIMPOL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31399">
        <property type="entry name" value="DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31399:SF0">
        <property type="entry name" value="DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03121">
        <property type="entry name" value="Herpes_UL52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00026139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="609" mass="71770" checksum="F95C52FC531BEF6F" modified="2024-05-29" version="1">MKSKDSRIPLNTVWNLMHAKMNTVYLKDYKRYAFQIYDSTAFKKESIVPKGSPTFSNLIDVKEMNLAAPYRSYDFFNIESNINTTANIPIIFNFGSIFHERRLLLTPSQDKILDGIRSSLHYSNPVLLSIAKRIVARLGGSGTFPRLPKQHRGKCKKFTKGNFGINDTTIAINKLNHCETIRRYDGEYKKFVVYVATDYRGTFQDNPIFSLLPQKFPCIYSMNDFEDEIYISKELETQPNLINKENLNSFDSSKPGKRKFLVATIDQFWNYYKRLLENSRHFYEIICEDVSSKLYFDVEYEINDYNKNLNSTELIGIFKNEVLKELNFQFKLENLEQDEVILDLDSSTSEKFSRHLIFNIPGHIFKNNYVVGHFVSNLIQKIKIKIIEKKDNYLELQKLFIHNYKDNMNEIFIDQGVYTKNRQFRLFLSSKINKNTFLNISKIESFHSKLNKKTIFMKSLISIPNINLTKFKILETFNSFEKKNSEYSVAQCLKTDSLKTTNNSVFPDLDKYILEKIKENVNSFNIRFRSAIWYNDSNTIVYFIEGSKYCYNILREHQSNSVYYIVDLKKNTFYQKCFDPDCKNFRSHQELFPSELNPFTDNEEILIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBE3</accession>
    <name>A0AAD5UBE3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PABS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBE3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.140.10:FF:000001">
        <property type="entry name" value="SPE3p Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000013">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030668">
        <property type="entry name" value="Spermi_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037959">
        <property type="entry name" value="MFS_SpdSyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002010">
        <property type="entry name" value="PRK00811.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000502">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="13"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3228045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="288" mass="32088" checksum="E5A1DFF5ADDCD334" modified="2024-05-29" version="1">MNHPNITELPSGIKWFKETEALWPGQAMSLQVTEVLHHEKSQFQDVLVFQSSNHGNVLVLDGVIQATERDECAYQEMIAHLPLNSHPNPKKVLVIGGGDGGVLREIVKHESVEEVTLVEIDEVVIKVSKKYLPSMAVGFQHPKVTVHVGDGFAYLRDNVGAYDVIITDSSDPVGPAESLFQESFFQLMRKSLREGGIVCTQGECQWLHLSIIKDVISNAKKMYPVVTYGWSSVPTYPSGQIGYVLCSTNSETNFRKPLRNLEEMKYYNTEVHAAAFALPQFTKKALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBT0</accession>
    <name>A0AAD5UBT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBT0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="164" mass="18496" checksum="BBA2B8F9713D3B99" modified="2024-05-29" version="1">MVTKNTALIAAGFLLCLQVFQFFLPLFHISLTSVIITAAVLSLHIVTFTTIYRNSNSTTKWILTTFILHVIAWLLFSTFFIITVFALVNDDSVPHPTLYTAVFLYSLVPLVIDIVLVSILVKYRKVLLANKKKEDKNAENLEVGKEPEVVQIPAPAYVETPYHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS88</accession>
    <name>A0AAD5XS88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD repeat-containing protein 53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">WDR53</name>
        <name evidence="2" type="ORF">HK099_001804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001550">
        <property type="protein sequence ID" value="KAJ3202583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS88"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042453">
        <property type="entry name" value="WDR53"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44666">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44666:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="270"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="331" mass="38552" checksum="E8298D908DEC88D9" modified="2024-05-29" version="1" fragment="single">MKREKYEIPKNNKGQVLSLSINPSKKNILVGTEESNLYLFDIATKNLVNELNTTKKNEINFVKFKKENEILFSSGDAMNLLDLRENKKIHLLFKCEEEINSFDLDDELILSGDDDGNVNTFDLKNNKFLKLYKNHDNICSTVKFRPGGFGEAWSGGFDFNLYQQDYMNLRFLNSWDLNLIKFEEPSRKPFLNPAFINCMEFTKDGKNLCLGLGNGCINLMRLKKNKNFLKKKKLHEKKNSSTENFEFNTNLDTNNLKKQIFKMDCTPKQIPGHNWAITCLKFLETEKQNSQLLVTGSIDGNFGIWETFEDKEKLLKKFFLNTKFNCFDILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSV2</accession>
    <name>A0AAD5XSV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001036">
        <property type="protein sequence ID" value="KAJ3207734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSV2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="1">
        <location>
            <begin position="54"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="431" mass="51139" checksum="E10F1F4F801AB403" modified="2024-05-29" version="1" fragment="single">MEDYGFLKSEEQKSYDFHYLEIMKRRLKKWDKLLEKSEVLPPKSEKLKRYIRKGIPPSLRKECWFHYSGAERFMEENDGLFDILQFRELQDIQAGYSRNDNKIFQHIEVLDRDVFRTFPDNSKFKRRNFPDSEEISSNSSTATLVNFDKFELEGESYYIQSLRKILVCFAYYSWPHPNPNRQLPKSCTYQIGYCQSLNFIVGLLLLIYSDNTIYETDENCRYEIEKRVFFTLVVIIEELLPKEVYGVNLEGTQLTQDVLWKWLFNIRGSRFGVEKTAQWIRSLENRKSDSSMPPLDLITGHWFMTLYIGVLPFETTLRVWDCFLYQGEKVLMRVAITIFKLYQEQILSFPEPIQSWKFVKEIPKKLHDCHSFMNIVFKPRYPIKPTEGSLENFGSQINGRESFDSQDENLPMISNTKNLSIRRGVGNIPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT89</accession>
    <name>A0AAD5XT89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000889">
        <property type="protein sequence ID" value="KAJ3210457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT89"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3210457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="547" mass="62720" checksum="8AF02F8968ABB479" modified="2024-05-29" version="1">MEISLNGLAWGKVQVELIKINVPNAGLIKHLKLAVSTSTHLHSKLKVYKVNEKLYLQDKRLQKNSNGLCSKIEDCQLNVNLLNQKNDFRSIEEIFNEKKDLFFDCNQIHLIFLWDFSINEEEINNDDNLILYKVPVNDELLNLERPPRYSMATGMDLGTSSSNFLLNMYSPSAHIATIDSPPLESTVDFESKRKSTNKHELLTQQFSIPSNQINAENINSKELVFNKSTSQLNQSHSNEFSMDDESSITTINDTNNIINFYSNYLPNISSDPVGDSSKQYLKTLSSLKNMKTTKFYKKKNFLLIFAFCTSLILILIIILMLNFFRESNLTTSSSSPPNENKFYEFNLVPFDVFNTTGEPEGFNNTDIRYPNLTNVVYSNVKYQIFHTSIQPYNNSFVFDISSLRALNYTYNNRSMSATYKFDIGMYSFTLLQNSASNSTIVTVPDDSIGRYFSDSYFFLFGSPYNLATKFFNIERPYMGFTLEYLTITNNIFPLVLNFVCNNTQNNTFELFDNEFDFSGINITFYSKAGCALCPDEKILDPELGDCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTD9</accession>
    <name>A0AAD5XTD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000833">
        <property type="protein sequence ID" value="KAJ3211450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTD9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="463" mass="53076" checksum="1C9C862EC01D4F33" modified="2024-05-29" version="1">MNLSFIVDNLKTVRPCKRQRLSSKTQYPLSPISANSTISCKSCNALESIDFISLKPAKFSKKSTFSPKTAKKIKVERCLFTDKDSTENPTLNTIKTEASILYAGQTLYNDFISNNFSASAFFNECLKNYVISIADSLPEIIQLELDFSTSNREHVNTIGSECKEFLRNCNFFYFALGKTLDKAIEKKILSYSKNGGYIPEYVSLMILEEMFNSLSLSGYNITTLLTLRGFFLEEICSVQQEKYHKVYLRQFNQLKLNLKNKSNQTITELENLYTQHNLSSVCKYAINFNTFSFHSQNNLKLVLHNYLKQMRKNFLNQFNEIDIELVEISPLNDIENDNFLPAYDCSKALAGLQITLSEDAVSSHTEINRYRKQHILSSVACYESTLDRLVNEEVWGSEEDNQLIKLLCCGGVYCNSESGKNPRVSMYSVEYPEENKIIIWTRIGYEESWVFNSFSGDNIVIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUA1</accession>
    <name>A0AAD5XUA1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000554">
        <property type="protein sequence ID" value="KAJ3215298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUA1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF386">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="3">
        <location>
            <begin position="155"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="847" mass="95650" checksum="0F500D3839872F5E" modified="2024-05-29" version="1">MPNTDDDFLVSGSSVVYDFNEQNVNGSNSNLQNLTQEFNNSVQQAASVLKLPTISEPISPTMKDFFQNDTQFYNKNSQYTINSSTKFENSDLPSNDLKLSVENKHFRNVEVANNNNADIKSFDGNVNSNFNSLRKERLRKKTGEVKFQRPSKEALDRAAIRSRLPPNKFSELEKMLFPKFFKEVILRRGFIELRNCVLLLWLLNPKKFISFPECFEKVGLILGEGGFEFSTMLSIIWNYLHRYRFINFGLFESPNIEATLETDNQKTSNLIPKKKKINIIIIGAGISGITTAREIQNIFIEAPEAERPNIIVLEARQRVGGRIFTFPLSSKFPNITKTPGVDLAAQIVTGFEGGNPLDVIIRSQLQLGLYYLKNASICPLHDIDGRPTDKEEDQFSERVFNECLNQACNSVLINGQLKIVTPLEKKFIASKTELNLSLGEVIDHYLQNHSSFSELSESQLRMFHWHQANLEFANATTLNNLSLHHWDQDDGYEFGGHHSMLKNGFGQVPEALKSGNKIQKEIKVKFNKIVDSIDIINTADGISESSTEGIVKVTCRDESEFEADAVVISIPLGTLKQKAIKFSPELPLWKSQAIERMGFGWFNKVVFVFPEVFWDPKVDVFGSVGSHVPGEINEYGDFLEIIYDPISYASNRGRNLVSTTGLPVLVSFVSGWAAVEMESESDAVIVNKAMTILAKILQGKRILNPIETIVTRWSKDEFSRGSYSYVANGSSGDDYDALGLTLWDKLFWAGEATNRHYPATVHGAYISGLRVATDISNRLLGPINDTNFKKEIFFTNLKKSKYSCWRKNCEHIIDERESLFDHISKYHQKTVASTNINSSTKDLNDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV49</accession>
    <name>A0AAD5XV49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_005128</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000389">
        <property type="protein sequence ID" value="KAJ3218255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV49"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF113">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CTSA-4.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3218255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="461" mass="52288" checksum="1A9B89CE099E1446" modified="2024-05-29" version="1" fragment="single">LVTSKPLFSTSFTSPSHPGLELNSLQLKVVQPNLCDETVKQLSGYLSISKKKHIYFWFFESRGDPKRDPVVLWLNGGPGCSSFTGLMMELGPCRIAPGGKSTIFNKYGWNQNANLMFLDQPVGTGFSFSEHGGPSTSEEAAEDVYLFFQLFFKTYNNFAKNDFHIFGESYAGHYIPAIAGTIHRYNKHRKSSSELLHIRLKSVGIGNGATDMLIQFREYPTMACDTKYGPILSNATCAEMASHYPMCKKLMEKCYETKTPLSCVTAETYCDSKIMAPYATTGRNIYDIRDKCGDNCYPIEKDKLVWLNDKKIQAQLGVDRHYDGCSDLVSKKFKITGDGALPFTKQLVELLEDKIDVLIYAGDADWICNWYGVKAYLKEMKWSKQFEFNQAEDLPWIGGETGREAGEIRTAGPLTFIRVFNSGHMVPYDQPEHSLEMLNLWIKAKIWDGDRDEKRRNELIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV63</accession>
    <name>A0AAD5XV63_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vacuolar sorting protein VPS33/slp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SEC1_1</name>
        <name evidence="3" type="ORF">HK099_005118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000388">
        <property type="protein sequence ID" value="KAJ3218289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV63"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="736" mass="83160" checksum="6F801DCE65A2297B" modified="2024-05-29" version="1">MTATSSIKDLVKKKILVDMIRSIQPEGKWKILVIDANSLAILNSVCRLNDVLDENVTYISRKRQAFPQQEAIYFISPIESSIQAFINDFSIKGKPQYSKAHIFCTSAASDDLFAMVKTSSALPFVKNWKEINVDFIALEKQVFTFNMPENFVTNYTANPSQEAISEDMRAMAKKMLSVFSTLAESPIIRYYDPSNLKVNKSYQLATALQTELDNFIKEDPEFPSKDAEYRAEGKGTVIIVERNFDMVAPLLHEFTYQAMLNDLLVLKNGKYSFKIEAEEDQKAGMATIDENDDIWRLIRHWHFADAVEYISGTFEKFISNNKAAAAALGHNEGPQGIESLNNMKDTLSALPEFQEMKTKFSLHINICQECKTVFEQRNLNLLAGIEQNLATGETAEGKTVRNGMQDLVPVLYDKSVPNVDKIRLLMLYIICQDGINDNDRRKLLEYAKLSIEECQAITNLSLLGLRLVPLTTSLEKKQVADLRGPYTYRGKKGDKRRTTNDDMAYDLSRYVPLLKLVMEDEMSQTISQKYFPFTVEPPTNATLKRNKASNEIKVSSQPQVVNGVLMGTGQNPYSLRTLRASWASSPTKKKISGADDNGKKPENDKLELDPDALLLKEYRKNGPRLIVFVIGGMTYSEMRSCYEVMRDSRREVIIGSTHILKPQAFVETLKDLHKQDIKLGNAAKTNPLLSRNSIAEIVEAPSTLTSSNSVYSMNPEKEKKNFNLFRKKTATTAVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVJ9</accession>
    <name>A0AAD5XVJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rap-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000322">
        <property type="protein sequence ID" value="KAJ3219894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVJ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11210:FF:000001">
        <property type="entry name" value="Ral GTPase-activating protein subunit alpha-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050989">
        <property type="entry name" value="Rap1_Ran_GAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711">
        <property type="entry name" value="RAP GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711:SF65">
        <property type="entry name" value="RAPGAP_RANGAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="2">
        <location>
            <begin position="157"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="42535" checksum="CDFB980F845A4AC4" modified="2024-05-29" version="1">MSVVLGNSDFKIEAPVQNAKITGVQESLLQESEKDIIWYRDNFFGKGTYYPDIFVTNCLATTLNIYLAHMNFLATDSPRGPMAISLIDDADNTYKALIRATQGSERLSVSSTAVTTSWWRSLFGLKPLPEDIFAALSRNIPSHNLKLCKDPNLPNELLQMEERQVIRSYKFGVCYLAGGQDTEEQMMGNKMETVSPAFKQFLNFLGETIELKGWKSYRAGLDVTNNNTGTHSVYTKWQGYEIMYHVSTMLPYNPNDRQQLERKRHIGNDIVVIVFQDDANTPIQLQSIVSHQNHVIVVVTPHGDLYRIVVLAKNGVPVFTPELPEPCLITKEAVGRDFFLHKLVNGERASYKAPSFASKISRTRTVLLFETATKGLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVK9</accession>
    <name>A0AAD5XVK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Selenoprotein O</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_004476</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000317">
        <property type="protein sequence ID" value="KAJ3220047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVK9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070733">
        <property type="term" value="F:AMPylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057:SF14">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3220047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="796" mass="91125" checksum="82303F7C16EFE6DC" modified="2024-05-29" version="1">MNRKNSSKRINTPSQKSSSLNITKPKKKLTDLTLIDNFTTELTPDALTPTGPLPHLDNAKPLKLPTNVEDADLTELVVKTSRMVKNSFYTFLLPEPCPTPVFILNVSNEAVKSLELDPNQEGLSTNFENENSHFEKVITGRALLNEDSKPWAQNYSGHQFGFYSGQLGDGRCVSLGEVLNSKNERFEIQLKGAGRTPYSRFGDGYCSISSCVREYLCSEVMYLLKIPTSRVLGIAACNRFLPRDKQEVKELAEHLIKNHYTELNLPDEAEIENTVEEAEKLNEHKEEDKEKIPLNVNIEKKKYSKKTILTLKLSPTPQPVMKSFSTSEEKMKYLKKEKMILDNYLKNSNQIEDGAGVIKVDVIMNRYAKLFLEVVKKTAILIANWQAIGFCHGVMNTDNMSILGLTIDYGPFGFFDSYDPSWTSNASDSTKRYTFDHQPKVALWNLSKLGRCFIDLVLKDLTTGEKIVPELPSTYEVNGVDIISEILKKFENYFSEELELKFRQKLGLKENIDDDLVTLINPLMSILSDTKTDYTKFFRTLSFSTVKQIEDYLAGNSKEGELEAFNLVLNSCASVQKKEGVLPTPRESLSDMQAALNGANELRNNHKSKDCEIEEFTNHYLPSQVEIRKRLKNWFQTYKERILLDFEMDCSKKEESQILKVASKTSLFENFENEKALLMKQTNPKYSLRNWALMELNDNLANEFPNIFNYSAQKNSHALFETFNSNLNNFKPPIQLSKQKCKEMIERVLRIFTEDLYGEISDSDVGWKNVEDRKYSEKLYQSNVEDLNNLQSVCFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVQ6</accession>
    <name>A0AAD5XVQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="11">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RRD2</name>
        <name evidence="13" type="ORF">HK099_004268</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="11"/>
    <dbReference type="EMBL" id="JADGJW010000299">
        <property type="protein sequence ID" value="KAJ3220477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVQ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3220477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="714" mass="81670" checksum="D1581A8E9BF02EF4" modified="2024-05-29" version="1">MLKSLTPLGGIIAFISSATHSPVLASCSLSILAYYFTKKLIHKSKDAFVKRSIMGKDLLKTDHPIIQEGLSQYLASLLSLFSMLFLGFADDIIDIRWRVKIWLPFLASIPMLMVYLVTFGLMRTTVKVPPFLRGLVGRGQSLVLALSILGNNIFKILTTFDPEREAHFNSFFFLLPFVGVTCGYLRHNWYPATVFGGDTYAYFAGMLFAVVSIQGHFSLTVLLFMTPQIFNFLYSCPQIFRFIECPRHRMPTYNSKTDKLEPSKVSINNAGKFGIAMIKVLDALFLVDLEIDPKTGKLEKCNNLTLINFVLIKSKNKTLSEEECCSRLLKIQSLVSLFLFFVKLSIATYWVYSEIVKMKKQILTTEDLNNFNACSAKSELMDFLHLLNNSIKNKKLSDLKVSDSSTLIHLKNLFKTLKDEIKNFKPVENGKSRFGNPSFRLWFEKVEELLFNQNLLSFLSLGDSQRDEVNSYLLDSFGNKQRIDYGTGHELNFLCFLFCLYKLNIFTKNKENIEVEMEVIFENLVFSVFWNGYINLMRELQKVYWLEPAGSHGVWGLDDFHFLPFLFGSGQIVDHKHLKPKSVRDKEILEQFSNNYIYFDCVKFINETKSVGLGWHSPMLNDISGVKSWKKVNEGMFKMFEAEVLSKLPIMQHLKFGSLIHFRGTDFPEDVVLNNEHVHAFGQEFPTCCGMRIPSSIAANAKGTDNIAKPLPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVX1</accession>
    <name>A0AAD5XVX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000900">
        <property type="protein sequence ID" value="KAJ3210247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVX1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3210247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="269" mass="29945" checksum="B806BE83970B0AF7" modified="2024-05-29" version="1">MIFIQISALLTFDVTNPNTFTVQITDIALSGSTGGGPSVKVGTLASYQFLFGNYSDTIADVLGFPIENSSVNRIVGKTTFLVAEDHGLQVNDRIKLYNFNVQPSIYTNLEHQGENEVYSEVSPDVFSIRCYTERVSDISNYQVLITTLFPHGLITGDNIRLNNTNSVPPINGYYLNITVIGLDQFIVSNFIDPLQPNILPLTITHSGFHGILNANQKFYLYNVEPVGGFTNTDLNSVPFNFREVIDENNFIFTGMYGFSLKLNLEVDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWI7</accession>
    <name>A0AAD5XWI7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000198">
        <property type="protein sequence ID" value="KAJ3221977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWI7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="359" mass="42480" checksum="71870F3450996BB1" modified="2024-05-29" version="1">MLKKKNLREGLIFYNSLRPFLKTVFEKLAKDQNLHALLFEVIEISILNEYDLPNLYSLIKEYEVMKMPLNLINGYFHKDSFNNDTSRLNKKILLNSINFLKFGFLNSEIRKQNKYNFQNIFTQLIDLILTNLTTVASDINRHFLKQINLLELIKLMIQFLEQVVEEEDYFNTEHLVAKFNIPYLTNEILEHLEKNAILKNSAVFDVMDNSCIEQLFIYKFRLLLMLNLIDKCNYQKIKQSNNLPILCSTLFTTSMDPDEMKTILFVVNKFFFEKSFFENVAVLNKNTKIDFLKLNQKVKEDETSVKFIKKEGCKSSETMDDLESIENMERVLVEVTEKFNLENKLRASLLNKKIEIFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWM3</accession>
    <name>A0AAD5XWM3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000650">
        <property type="protein sequence ID" value="KAJ3214096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWM3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="194" mass="22303" checksum="AE0143F0DE370184" modified="2024-05-29" version="1">MPTEFLKVVPSQLKKPLYHTTKNFLSLILPKDSRTGIQSITTPTICSVKKKIIQWEIDLSCRAMNEVEKLTSQDAVGKVCPNADELVLGILKRLNLDPEDRASDKGSYKLNLNLSNFKKQEIQLQPLDIRDNHQFPTMNIISFSKSFFRMLAEYSSDEIEIKWLSILSSVQGTSTLKLFRERNANVFRYFNKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWW5</accession>
    <name>A0AAD5XWW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000172">
        <property type="protein sequence ID" value="KAJ3222522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="580"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1807"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="650"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1358"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1438"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1569"/>
            <end position="1659"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1728"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1817"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1830"/>
            <end position="1846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1982" mass="226240" checksum="2E28E95C5A987BE6" modified="2024-05-29" version="1">MRDPIINAEQLALTPEKSSSVPITKFNSLLNHLTDLSIAIDTNKPPVTENAELGSLYSSFTDGVSFLEDSLNKAQEENSMLQLKVQLLEKELMEKNISEKLDLQPSSTSNSNLTSQDSAVDLVSQLESKEREILKLENKYNSVVNNVQNLVYAVETGNSVKELNFGDDKLSTLFQSFVGNLNKMEDEFLTESESQLTENIMTLTELLKSGNFNMMNDIIAVGPEKELISILKLLVDKLPLISETIDKSVEKIEKFDKDIDNENNLLKLSKLAETIENVNFKIENKQDWITRQMDQKVTALEKSISVLESGNVSRNWELTIPAVDISVSELQQSTVDAHLAQSYVNDVTFLRSQNFENNKPVLQLQQSTVDAHLAQSYVNDVTFLRSQNFETNKPVLQLQQSTVDAHLAQSYMNDVTFLRSQNFETNKPVLQFQQSTVDNHLTQSYLNEVTYLREQLRNAYENNTDAIKNYSSENDNDVAYHQQILDDHLTQSYVITIESLSQSIKELDAQKLSIRRMSADQHVLDSHLSQSYLSDISSLRQTVQDLDWECFNLKNRRRPSVEKAYVHGTADHVSSLKQIKEEGSGEGSVGSSSGSGTPIDDRQTYITPPRSPPSVHRQKSPGKVYSQFTDSGIDIASLDHRLSVSYREGLDSPEEELDNLRQQLLNREAEMDAAINRYESYIDDLGRKLTKTTEVTNAMALALSASKKDNQELQRVAKLAAIDYDQAVLENHLLFSYLEAPVSDTETPNTNLDELMVKYDQLVLDNHLLLSYMDEKLHISSEFSSLMDIPRKFSLDLPESLGDFVIIESDDESHFEILNNHYELKDTENSAEDLLLHRELEVEISTASYESKIDELTRQNRFISLYYQNTINAWKSSMEEIVRLKNECNKLESLSTQHSAGGEKISNLLEEALARNEYLETKLNQAVVDQHLMLSFQNDSILLVENKNAENNLIGQIPTKKKVKQFFAENSSQELAVSKQGISEEEFNSAGSVEGSLVEETEFEHKYHQLVVDQHLLISYLLENQENYPTENEISINQLVLDNHLLQSYYIQISEEIELLKESNLVSETDLNCTKTQLATVSSDYISVSKITNWVNNERFDLIDELNHTKLKIATVSSDYISVSKITNWVNNERFDLIDELNHTKLKNEQFKLLLSNSDQLVLENHLLQSYHNQSTEELSFLKEELKNTYTNLQPSKQVELKGADSDQLILDNHLLQSYHIQYTEELLQLKQESAKNLTELKSTTEKLLKLTDDYQVITKINSWVNNERFSLIKELDISNTKNEQIPLLHSQMSELNQKMEQIILNEQLLLSYQLDVHSLREQLNEFKNKELASEFEVLSASVSPALKSVDSPESFKIVEVERTLEIKKLELAASEKKIQELNDELSKFKNYSFTQSSAIDYNSDVDSVTSTSLEEEEHGKKKVIIRFRKADAEDTKLKEIDLLLQEKKKELNDSQKVIAELNQRLAEFHEKELQLKSQSIAEVPKISGNSRSTRRPSQMDVERSKIKEMERLLEGRETELGQMVLDHHLLLSYQYGAETDHSIAAATTVKGLVSPNSIETVTISLAELEALKADADKCESLTQKLKDTEARLRARDLYLQNTIMDTAKRVAELENRLIEQQGVNEDLERELKLAARDKEEMENELQDLDHDNMILQNQLNHSGTSQVDTFDLEAYEESELGDDYVVLRDMEVQTDLTVEQATSEMPSSSEQQIMSVVSRLTYSNMIVDTQKETIQELESKLKKVDIEKERIIQQSFEKNMELERIQAVNSQRAKLIDELWKRVEKLETDRTSIHLKRTVTLLSNAPEYRSERRGSTKSTRSTISQRSQSARDEPDYKSYHQDRRSTAGSSYLNDELVNSVRETRHRLPTNSMYSSAPTEVSVDTVLDSEYIKNIPDVKYKQQDSKVTHPKSLSRSSTINEENYSNFAGNNFSLKNGRRKSISISTFPNSPTNIVSDIPQVPSHGSSRISMLAAREATPWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX21</accession>
    <name>A0AAD5XX21_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small-subunit processome Utp12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001629</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat PWP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000148">
        <property type="protein sequence ID" value="KAJ3223013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX21"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25168">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="340"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="382"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="468"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="510"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="7">
        <location>
            <begin position="740"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="945" mass="106931" checksum="1433DD04F83FC681" modified="2024-05-29" version="1">MKLNHKFTNLMGSVYTGGNIIFDENKLISPVGNRVSVFDLVNNKSHTLACENRCDIMTIALSPNGNLLITIDEEGRGLLINFKRGIILAQNNFKKPVKNLKFSPDGKYFAITLGKQIQVWKTPNFNREFSPFQLHRTYTGHYEDVLHISWSNCSEFFITASKDMTCRIYSLNPIEDFIPVLLSGHRDSVVGAWFGNTDMSVVYSVSKDGTLIEWRKVLLNPDFGEKYHPVKKKRGQVLPPVKKTYKWKLHAKHYFLQNHAKVVSTSFHQESKLLTVGFNSGIFGIWELPEFICVHTLSISQNKITSVAVNPTGEWLAFGCAALGQLLVWEWQSESYILKQQGHHYDINTISFSPDGQFIATGADDGKLKLWNTQSGFCFVTFNQHSAAITGTQFTTKNSILFSSSLDGTVRAFDLVRYRNFKTFTAPKPVQFSCLSVDPSGEVVCAGSNDTFEIFIWSVITGNLLDIYTGHEGPVSALQFSPTDGSLVSSSWDKTIRVWDVFSRDTNVEVFQMDSEILSVSFRPDGAQIACSTLEGNISFWDIKEGKMDYYIEGKKDLIGGRTTGSLITAKNQHFESITYSADGSCILGGGTSKYICVYDIISKQLLKKYQLTKNRSFDGVLDQLNSKNMTEAGDINAIDDEDYSDLEERMDKSLPGAKIDPSLRKTKKTIKVKSVLFSPTARSFACATTQGLVVYSLDDYLLFDPFDLEIDVTPDSVLELCKEGDFLKAIIFSFKLGERELQNFVFKSIPSELSTIELIIQGIPTKYLEKLVKYLCFLMENNDVEDSQLKNKKLELNGTGSNLNLTTNSAINHYNNNNNNRIEFILSWLTLTFKIHGRFFKDRKYEFGSVLRLCRKRIGEVYDDLSEVCDSNTYALQYILHAINQKQKKKDDNEKIFLSNGKFLREEINEEEDTLEDKIEGAYNLNNFNATNENPNTMEDILGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX56</accession>
    <name>A0AAD5XX56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000510">
        <property type="protein sequence ID" value="KAJ3215918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX56"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="868"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="887"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="922" mass="108003" checksum="6861F5FA55A90087" modified="2024-05-29" version="1">MFDKLPINEKSAEVRLGDLERFIVLNVRSFFSLTSEKVCKRNESKKVRNICTTVKSKRLNFFSTLNLNSSLLNNFTNYFAVIEFLCNCMESFFNQFKQAATSNIFSKNGVQNDRTTNKLSGSTSNLNSFHNTTLQNRAKPNNSLNLNLDSVNEVKPTQASFFQEATQSKITESSAISSDKRQTMLSTVCHSSQLPFDLLEKGQSVSHEKKSTDPIQPLQQQPKLHLSSENSPENQSKYNHPEKPLKIHHQQHFQPRQPQQLDYPVNEFNSPKQHLEKSPTKHFIHLPTTETSIQNRESDKSNEINFSPNLRVSKTLSASPASRSSKSNSKTNEQVSTSDYRSRFEEFKYLKRVREEYAPIHEEPRQFEGRRNDPAKSFGTNFSREDRNDIKRNLHDEKRRVARTEHIRENPNIEMVRIEDRYSEDLRSFERGRGNEFSNRHSDLRFERDYVSRLDMVRQEVHRKDWADPSIRSRSIDRLDYDWGRRSLDYDRSSSLRPERLSASEGYERFGYYEDRRLLDWRPDRYDERYDDRYDDRFDERYDDRYEDRHDDNWEVERNYSRAIMSHSRLENEESKIRYAFDRINSLSRRYQGFPPTPVDSPYQRELTYSRSKSKEPLELKVRAKETLEVKVRPKDPLDAKVRAASRINDYIKPYDNPLRDKKRVKLNNDKQDRSISLSKFNSIPRIPYQNAIRVNGTLTYYSDSFLEDPWKQFGTLPGEYKWMEIISKTKKRKKLGENKLNDKSSSISTVLNTEVINNLVVDDEKVNSSTVEGSKVHTTENVMQKLIATGEFKTFDTTKSNSILKTSSTEYRDSVEKSVPLVITENSSSVTLPQNENFVDTQHCKVNNKKPNLVNNNGVDKNNLRIEDSENHGQRNQISDTDDNFTSDRNKDKNSKNFSYYEKINNYRSNVKLNEGLGCSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX90</accession>
    <name>A0AAD5XX90_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000127">
        <property type="protein sequence ID" value="KAJ3223511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX90"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="82" mass="9499" checksum="27471F9097859011" modified="2024-05-29" version="1">MKIWPESPAKKFKRWGREIMELPFQISNSILATQKFIINLPKNVIFGVFTTAQLFVNEFNFVFFGGSRGNYAKKNCNYDSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXI5</accession>
    <name>A0AAD5XXI5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005537</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000436">
        <property type="protein sequence ID" value="KAJ3217256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026054">
        <property type="entry name" value="Nucleoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039462">
        <property type="entry name" value="Nup159/Nup146_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23193:SF46">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16755">
        <property type="entry name" value="Beta-prop_NUP159_NUP214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="9">
        <location>
            <begin position="1156"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="475"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="561"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="598"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1224"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="606"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3217256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1905" mass="203879" checksum="D61AF01997B1238B" modified="2024-05-29" version="1" fragment="single">MIKELQTFDSETIKFVPLQIDAKLKVSDPLATTASVNLLAASNIYGYIVAASDSGFKFYNTKNLVHSFKISENKKVNYESEVVVNIKNSKISHLRLSADEKKIIIGTNKNEILVFEAGSVEISKGNLEPSKTILFSKPSTFTDLKPNPDQFPNLCTILFDDGSVLNVDVTDGKIIESKLNEKISSICWSKQGKRLACATVTGDIIQFTPEFEEKKRIAPPPSFIEEFGSEVSIKSLTWIENKTFLAYFLKNDDSEYDSATLYCIDQVGNEISYQKFVDPPLFSRQNEAGINYYYEYIPSWGKQSKYFVIYGEAGSTDIGFIQASENPATPNNYTWATVTLSDYVTLPLKEDDTETRIVGFALDFTSKEETRQLNIPDPIPPSPILLILLDDGNLVGYHCFDTALQESTNAMTTIKPLEVEHNFVRSNNPPSVISNNSTSFVSNSFGITEGKNNDSSVLDTTTKIKEQNSGFSSFGSFNLNSKKENNEKTSPPKSPFGSFTASKPSDSNSTFGFSALKEPSKSNTGLFNSTPFKAASAFSDAAQTPSASGIFGSKFSSFGSNLGGKESENESSEESFQFGSSTGNNVIEKFNNNEAGMKKSGAGSLFGQSPAATSSDGKSSFTEHVERPGKNPATPSIFNLDKKVTPLKIEKNIFSSSISTSPTVTNTPTSAVFNATAETDPSFQSSKGTKLLVDNFDLMYREFEQDREAFNDLMRDSLNKWAEDVKSRFTENTDTMKLLSTSDWGFNDLNLLLILREDLSDLVKKAQSDFVKIGESFDKINNNFYSTKRKVLECRNYLEQIENNKKIEENRKGKQYFSLPPEAEELELAVKVVSDYIQGKIKNENQLSGPVLHKISTSITRLFAFSQEITARLNEINDMLKNNVDKPNEIKAALNKKKKKKKGYGLFDSEDEENAVAEITEDVSELCLPKSDGLEFEKRHKKLEMLKSYYDNPSRTVFENKKLVVKPKTNWIRALEEDVEDVINESIVIENEVADKKDEVDKSIGSKGTSIPAPPTLPLVADSLVSSIFSSASPMIKVNIDSPVGTPVESPSLSLFDSPFSKISFKKSNLAETSAPTTTSGFNFESKGWNCKKCFFNNKDGTQCKSCKTTHDFQLGNNNGVTKAFTSASNFGAKSSFNDGESSKSKPFTFADLGFKQSGWNCTICLSTNQENINCCLACETDRFPVAVNKAETKSPQKKTFTFGSSTSVATSWTFGAKTDPNTKSPFGLKTDSDTKSPFGLKTDSDTKSPFGANGASIDTKFNFGENANIGEKPQECTEQVLSSAVNHMASDQSPQKTEGTVEQGIFEDDSVVVDSEDAPSNPEQGDKVNYEGDEVDVSGVMVSGADGSNTDVSDLSYNLVKSSEDESPVNSVLHGDDELRDSISAIQLSPTKPGSLTKEIIDNSVLDKTEKLEDASPTKPASSVKVQESAFIVNETDSLNSLFNTSTSLGDKCEIDSDKTESSLKASPLAKTNEGVVFGTPLKTEKGLSSKESDIPTKSISTAPVFGSSSFGKQPSPSLLSNLSVSKPNDGGADTPSLFGVSATSPFTTQPKNTTSVFGTIPSTVTTLPFGAGVASTASPFSAQAPPASSPFGAVSATTASPTSAFGMQPQANSLFGAQSTIAPSAFGIQPQVTSAFGAQSTTAPSAFGIQPQATSLFGAQSTTAPSAFGVQPKATSLFGAQSTTAPSAFGIQPQATSAFGAQSTTAPSAFGIQPQVTPTFGAQPGFGNQPQTAFSAFGANSTSTPSTSVFGSSNLNSNALPSAFGSGLNSSPAFGSVQNNSSFQSAPAFGSSSFGGVTPAFSSNSFGAPAYGSSSFGSQPAASGFGSLNNGNLASNFGASFGSTSFGAPRTGMPLNSSAALASLQSTTVFGSNTATPPSANNFSGFAQLASKDNDAATIFSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXI9</accession>
    <name>A0AAD5XXI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C-1-tetrahydrofolate synthase, cytoplasmic</fullName>
            <ecNumber evidence="8">1.5.1.5</ecNumber>
            <ecNumber evidence="7">3.5.4.9</ecNumber>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ADE3</name>
        <name evidence="21" type="ORF">HK099_000117</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="7"/>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000101">
        <property type="protein sequence ID" value="KAJ3224195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXI9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000006">
        <property type="entry name" value="Bifunctional protein FolD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000245">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001123">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000005">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.410.10:FF:000001">
        <property type="entry name" value="Putative formate--tetrahydrofolate ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.410.10">
        <property type="entry name" value="Formyltetrahydrofolate synthetase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF5">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="18" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="16" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="19">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="20">
        <location>
            <begin position="142"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00017592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3224195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="944" mass="102515" checksum="DCB462DEDBD2B5F2" modified="2024-05-29" version="1">MSTLINGKLIADSFRKNLKKEISELKQKFNDFQPQLAIIQVGNREDSSIYVKMKQKAAEDCGIKFLMKKLDNDVAQIQLLQEIEKLNNDTNVHGILVQLPLPSHISEVDITEAVDPTKDVDGFHSHNAGKLAKKNTPPMFVPCTPKGVMALLKETGVSLMGKNAVVIGRSNIVGLPVASLLQAADATVTICHSKTINLKEICQRADILVAAVGKANLVKGDWLKPGVIVIDVGTNSVADSTKKSGMRWVGDVEFDSAVKVASAITPVPGGVGPMTVAMLLSNTVESAKRFLIGFERKTQYLKLNLLNPVPSDIDIAMAQQPKLIKDVAEELGLFNSEYELYGHYKAKINLSVLDRLKNNENGNYIVVTAKVINNLGITPTPLGEGKSTTTIGLCQALGAHLNKRVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAVVAANNLLAAAIDARMFHESTQSDTAFYNRLVPAKKGVRTFSKVMLKRLKKIGISKTNPNDLTPEEKKKFAKLDIDPETITWQRVVDTNDRFLRKITVGQGEQEQNKTRQTGFDIAVASEVMAVLALTRNIDDMRERLGNMVVANSTTGEPITCDDLGVGGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADQIALKLAGKPANDFEKEKGFVVTEAGFGADIGMEKFFDIKCRSSKLIPNLVVLVSTIRSLKMHGGGPEVVAGKPLGEEYQTENIKLLELGCVNMMKHIQNAKKFGVPVIVAINKFTTDTESEINLVKAKALEAGAVNVSCCEHWERGGEGCVDLAKSVIKACSEESNQFKFLYEVEDTIENKILKIAKEMYGADGVEYSELAKKKLEVYTTQGFDKLPICMAKTHLSLSHDPKLKGVPTGFTIPVRDIRASVGAGFLYPLLGTMQTMPGLSTRPCFYDVDLDPESGRVVGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXL6</accession>
    <name>A0AAD5XXL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000423">
        <property type="protein sequence ID" value="KAJ3217512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXL6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="462" mass="54034" checksum="86ADB4D04424F67A" modified="2024-05-29" version="1">MSSSLTSFNNIPSNSLVSNDSEYSSFNNTLEKWKWTSNWTQEQLDILNIEYRDADKLEDITDINSIEELYSESIELFLPGVNLSDNPFKNKKLTSNQKLFISEVQKSTIKFDDELIVDGLISRLLDATYFINDKINFRRQPKIEVKWKDYNIISKADFGVYNNTNVTNRFTEYLMIVEDKKMTFKSKIEHQLAGELFTSLCGRESYSLKDYTNYGVANRGVYFRFYRSKMTATYYKDISKDKKPLAKLIIYRYPKECDEPLSLVNEKDREQILKIMSSIRQDIETDEPPVDAIAYELLNNIGYEGLILHFRPKPHLEFKWQGYEIASVPDYGVYVGDDIEEFAEYLLIVKDKPAGKYSYLKGECQLFGEMITAAINNYIIKKEQQNIYGMTIRGSYIKFYLSMFDKEYLSNIINDKKPTKDVNIYRYPSDDSKGLSLNSTQERLHIVKILKTIKEIIESKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXZ8</accession>
    <name>A0AAD5XXZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 26B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VPS26B</name>
        <name evidence="5" type="ORF">HK099_006840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000615">
        <property type="protein sequence ID" value="KAJ3214505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXZ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000010">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3214505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="407" mass="47215" checksum="03DAEE6585327CC8" modified="2024-05-29" version="1">MDLDSNWVVDLWLQILLTNYCALEVVVANFIFASIVLTNLNRVGKFTASVGLAPNTNVRLDLGNCWHHHVFGTGVRKNLNTQQFNIINSNEYQSIFGLGTQVDIEIAFNEDENSLKKRSYVDVKTQEKQKQKFPLYFDGEAVSGKVMVRVKDGKKLEHQGIKIEFVGHIELFYDRGNHYEFASLTQELAAPGELRQNATYDFEFKNVEKQYESYFGINVKLRYFVRVTVGRRLSDVTKEKDIFVHSYKMPPETNASIKMEVGIEDCLHIEFEYNKNKYHLRDVIVGKIYFLLVRIKIKHMELSIIRRETTGAAPNQYNESETITKFEIMDGAPVRGETIPIRLFLSGFELTPTYKDVNKKFSTRYYLNLVLIDEENRRYFKQQEISIYRLKESDNLIPGLSSVSLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXZ9</accession>
    <name>A0AAD5XXZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ACAP1</name>
        <name evidence="9" type="ORF">HK099_007078</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000066">
        <property type="protein sequence ID" value="KAJ3225252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXZ9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="244"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="8">
        <location>
            <begin position="369"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="549"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="588"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="678"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="690"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="764" mass="87297" checksum="B8AF6F3A29022210" modified="2024-05-29" version="1">MKFFEIPLDEAFDDTPSFRRAMSECESRLVLLESIIKKIIITTQQISENHQILNQKQLLLASEIQNLINLDSSNGFITKSGLPKISSTIEDIERSRTMMTAHISGEKRNLYFKFNYPLDVFIDPLNKFITDEILPIKNLKKERISCLDHYESTINRYMKKNNEDSLNFAVEVSDGFEYLKDLEPSIRDVTVTLNKIRAEFKEKYEKDEKAFLNSKLKSDEYYNPLHQSGEVKVQATKLQKLSNKTGKGSYLYIKVKGAILTTWERRYFELKDDVLHFFSDTKDQQKTTIDLRICMVREVQTPERKFCFEIVSPNKSFILQAENEHEMKDWISVLQGSISRNLQAVPTQKNKNNNESKFSMDEISAVPTVDVMSQIQQVPGNLQCADCGNTEERTILINNINNYLKIFSVEWASCNFGILLCITCSGVHRGLGRQVSKVRSLELDRWDPSTVEFMKNLGNDRSNKIFEAAYKPEKFDVKKPLKETNRNDREAWCKLKYLEKAFVRMPFDEMNLVENPPQAQLWTAVKESNFVKALRAVGLGASLNACDMHGRNAIQLAVSNNDIDMADFLLQWNSSPNSPDSNGLSRKSFLSLMHLAAKSGNLNMVVLLLKRNADPSAEDVNRKKPIDYALEKSTTHEDYVKIVTILRLTELNRETRNNSTWRSNDLGIEEALADLKTKSTAGSPHPVRAQSRSPSPTFSTATFPQKLVPEFIIPFDDPLQNLEAPVSILDKFIPKKSVSNNSIYSAEEHDPWTANANQAWNDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY57</accession>
    <name>A0AAD5XY57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-glucose 6-dehydrogenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">UGD1_3</name>
        <name evidence="3" type="ORF">HK099_006463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000056">
        <property type="protein sequence ID" value="KAJ3225630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY57"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006024">
        <property type="term" value="P:glycosaminoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028356">
        <property type="entry name" value="UDPglc_DH_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374:SF3">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374">
        <property type="entry name" value="UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00047473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="84" mass="9244" checksum="83CF10FA5F9E7FDD" modified="2024-05-29" version="1">MFSCPQVKVIICDLNQARIDAWNSDNLPIYEPGLDEVVKKARGRNLFFSTDINNAIQEADLIFVSVNTPTKKRGEGAGYAADIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY65</accession>
    <name>A0AAD5XY65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Intradiol ring-cleavage dioxygenases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000055">
        <property type="protein sequence ID" value="KAJ3225689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY65"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050770">
        <property type="entry name" value="Intradiol_RC_Dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711">
        <property type="entry name" value="DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33711:SF10">
        <property type="entry name" value="INTRADIOL RING-CLEAVAGE DIOXYGENASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="Aromatic compound dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Intradiol ring-cleavage dioxygenases" evidence="5">
        <location>
            <begin position="16"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="256" mass="29759" checksum="3D84E0A3AB7B85FE" modified="2024-05-29" version="1">MALDVAKECRSTSVDIEGPYYVDGAPFRKDPKICQQATFAHDRLYMQGSIFSSDDCETPLAADLDIWQADMDGKYSVGEKDQFFCRAKIVTDNNGYFQFESLMPGRYDDGGFRPAHIHFKIIPHNKSYRNITTQLYFENDNFLAENDSCKRCHSGDPTITTKLEHKKDIKTYVGKWEVFLPKIGKESNVVIMSRERDNYVNKKSNIFRNNVEKVIVVIDLNYFLVFFACLVILCFLFLNHLPRRSVIERNIFNRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY81</accession>
    <name>A0AAD5XY81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Outer dynein arm-docking complex subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tetratricopeptide repeat protein 25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TTC25_3</name>
        <name evidence="10" type="ORF">HK099_007022</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY81"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040111">
        <property type="entry name" value="ODAD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23040:SF1">
        <property type="entry name" value="OUTER DYNEIN ARM-DOCKING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3225287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="650" mass="74287" checksum="31D8EF68CBCD31B9" modified="2024-05-29" version="1">MASKQNNGKIADDVHSELEGPVSSFQSYAAEGDILAKQGDLRKAIEAYTKALEKRPGDKNCLVFRSKCYLQLGDSQSALEDAQESLKEDKEFFKGIFQKAEALYAIGDFEMALVFYHRGNRLRPEFNDFRLGIQKASEAIDNSVGNPDIHKFQAPPNFKKETLIQSEVKDLAAATLNLNNSSKNVDGQAFINTLQPIKGEPISKDPSVRQLLGELYADKVFLEEIANDKDFVSNPNPEISNLVNSALIYLEKRTEFWRQQKPIYARKKEQSNVFVKAVSAKNRRTLHETQKNLKLVEDLKIGSNERLVHQLKIENEEQKNIEATLKLVRNAFKRKDFVCALETTESVIERLGDVLDVDQRKYLLSECYGYLGNIHSEMGNLAQSVLYHKKDLSVSNEIGNFDGLKRSYGNLGIAYVKLKRFREACTMFQARLKVSKKTTCISETAPAKRIIREKFKKLNNNSISVNNIKIDNLEKCWLLHDIARCKLEIGEIEDALNFALESLTYSETSKDKEWILKCKVLVSQIKCYKGNLNESHLLHLQALQLSVELGDKKTQSLIESSLLEIEKREEFSLIKRPKAMTARANNEVETNRRVSILERKKKYHDKEKFLILPNNSFSFKRNNIKVISTVIKSNNSRNNEEKFKLISIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYC3</accession>
    <name>A0AAD5XYC3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alpha 1,4-glycosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004227</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000293">
        <property type="protein sequence ID" value="KAJ3220537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYC3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006688">
        <property type="term" value="P:glycosphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007652">
        <property type="entry name" value="A1-4-GlycosylTfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051981">
        <property type="entry name" value="Glycosyltransf_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042:SF21">
        <property type="entry name" value="ALPHA1,4-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042">
        <property type="entry name" value="LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04572">
        <property type="entry name" value="Gb3_synth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="9">
        <location>
            <begin position="433"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="9">
        <location>
            <begin position="522"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="128"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="611" mass="71604" checksum="5DF40727ABE64588" modified="2024-05-29" version="1">MIANKTKLIGPFLFFVCIFQAFTLLGNTLFSRYEKNAQNVYFSNDVTSEESSAKLEEYKLQLVDSIKSKKLDYLGYDVNKKDFRNVKFDSEKLDMNLKVNDKFQIFGKKNSTPLDMDTTENKRFKLWKSNAYLEKIKLEKELKELKLLEEEEARINETLRAEASSNNEEKVNNQAQTAENKIITIENTEEINQENIPVKESEEKISEEKVAEEVQDKKEEEKVEELSPENTCRNFHAQSRKIPFNFSNGDGESFNFNGMTIRSFANAVYNVSEKSEEILSKEISSPINVPKVINFFNYNPTFDTVAAVESAAMHNKDHYIKIYVRNTDDFNKKAAVWLDRIKFNYRLRILPLNFAEKFYNTPLQAWYNNKEYLNSDWQFQNLGNAFRLALIWKNGGVYMDMDIISLNSFKDLKHIRLVAREDGTRINNAVLSFPPKDPYIWSAMEIFVNNWNGYNWGNNGPLCLSRAMIRDCSWNSLATAKMEVFENFKPKGRNVKRHSPEREAEIESNIEYLKKYGSQVTRPYCSSIVTASRIRFYPVHYSQSNLLLKDWWENCNLLKYIYHKSVGIHWWNRMFKFKKNKTELSPNSTIVKIFNDQCPKFMDSYGLKQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYD0</accession>
    <name>A0AAD5XYD0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000528">
        <property type="protein sequence ID" value="KAJ3215662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYD0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF15">
        <property type="entry name" value="SPORULATION PROTEIN RMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF155" evidence="2">
        <location>
            <begin position="233"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="778" mass="89911" checksum="15C8794D27AD7922" modified="2024-05-29" version="1">MNISDTDHSSNAILNRNLQHNPYVDSFPRGSPVSPYPSLEDYHKKSKKYLKQTSILTSIRTTKKGQKLVLLPDQHPVNLSEPNSKQQSSEEFFSHLIQEKQDFFATPQHTTQAERTLKEDRFDLPRVSSYCVAEGYKLEEITKFLNYSHGVNGVSYDECLHASYEVSTKFAVLGLERPLFLKKMTSRPLQEEKPLSPFSTDGSSENVVGDVRSPNIGYDSIPTFPLWMLRSDVFFFDYGVIVFWNFTKEEEEKFISLFKQFAINPIRFDNYEVDELNFQYDLSGPQQPRIFNDIITLKSSNHLIKLTISHGIAQSVKLSLFCNIMEETIDSTIALPHEMSKYGKINMERTEVMKIVGELFDLRMNVNLVSNVLDTPEIFWSERELQGLYQAVRAYFEISQRAALLNKRLEVVGDLLNMLSDLQNFGNIFGCSLNFINLFRKDMESIKSSNNNNLDNFYIIEDNFPKNNISKLPFIEQNRRFVQFEMEDSNIMNNFSKNFIDYNLFENIKEKNCSLDNLDLIEANYNKPIDDVLKFDDTRKIKVKSKGINYSEDCIYYKKRKITLSTKPLNRNQIEINKNLYQIDSKEKIYYLISNKNSKRLSCDEAGDNKITEYRSLSNLHRLQKLMQTDAETGEYTSGSPACFMAPPVNLKKSAAAEDELKAMEANDSNLKNESFKGKKVLKFFRNAETKWIKTEQDKKKDFSKTDSVETNTKVHSRNFPMKPFGRDDDGNFGILSGGKLKQFSEDIIKANFSTAVETNGKSSIENSNFEQMFCWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYM6</accession>
    <name>A0AAD5XYM6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_007179</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000675">
        <property type="protein sequence ID" value="KAJ3213798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYM6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="2"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3213798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="363" mass="39950" checksum="0151AAD5F387490E" modified="2024-05-29" version="1">MDVLFATLSLCYILGVARNATFIIFPVIASLYIFIFFYGSKIEKANSVYLKFMDKRIKTVSELFSSIKSVKFMALEKDYLEKINTARKQELKANLSLVKHQSIMDAVSAIGSALLSVAVFTIAYLCFPQGTLNVQTTFGCLSVFSMIQSPMTFVIVNIGVLFQSKESIDRVLKSLNASEVDKSQNSITKSNILNNNDAASIELVNCVVEWPGTKSESVVALKNISISVPKNTRLTIIGQVGSGKTALVNTILGEMKITSRSKAESIGKISFAPQEPWIFNGTCMENVVFNSKFDAEWYNKVIKACCLDLDFCNFKKGDQMLVGEKGLKLSGGQRQRIGLARAIYAKSEIVVLDDPLSAGKIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYU5</accession>
    <name>A0AAD5XYU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003127</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYU5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="288" mass="33608" checksum="D196B94CD3CC40D8" modified="2024-05-29" version="1">MENFSLLPNTPIDDITHEQDDFTHQLNLNYFQPQFQYYEQQSQFNSAPNLNYVPLQQPNSFSLNNNNNFNTQNFLNKQSDFGFYNLLNQQKTLVSIQQQEQQNFQKILPTMIVQKKREPLFKEGLSSSYPPGLLSVQELNKSIAPERFPCTRSQYCTKVYKNANGLKYHLIHGICEISDQEKNSSSLVTPIGTPEKNSIEINKSMIPVELDENEDSPNSRHFKTFIEGVPESERRDKPYFCKVNLCGKRYKNENGVKYHAKSTHPNLDWKQIYGHDSETRSNLRHQPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYX5</accession>
    <name>A0AAD5XYX5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005471</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000428">
        <property type="protein sequence ID" value="KAJ3217430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYX5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF27">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3217430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="377" mass="41814" checksum="8E7ADEB1A4699DCE" modified="2024-05-29" version="1">MITKSQECFDSKNLSCANSVYQNATLDLSKICTSNSAIVGCSILRDCKEKGKSTSFCNEFSILGDICYSDKPSLGDCLQYKSICGISGLVGDQITPSSFNAIFNNTTILDCEINHPLTNLPPTSLVKTKVESVCKRMASMDGCSSCMQNGVSLPTCNLFKTYGNLCLQMPMNECNEWKKMCDSSPDLTSFCTSAVEDDTPPSSPTNKDSSANKEVFQIPDMLMFFHSGPVDYILFKSLVPQNSLHYAIAIVILFFLAVFYEWLHVFSILKEEEWKLKNYPAICYPYKPLNLKEVKEEDENNSQYIGLKILLLRGLFKFLLTTLSYSLMLIVMTFNIGYFFAIIIGYTVGTMCFGGLCKRGSNTISASSQEASASVCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ58</accession>
    <name>A0AAD5XZ58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000192">
        <property type="protein sequence ID" value="KAJ3222092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ58"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="569" mass="67285" checksum="D5C00A8D5AE6B150" modified="2024-05-29" version="1">MQLYQNDDKNLLSYSTPKKLKFKTANLQIQNLRSLLRKALLYNGEMREESVELQLKIFKILTSFTNENSTFFGGKSFNLTADNLILFGSEILLRDFLVSKEGNCEEDQMDFCDEDEHGARTNMMLQFFKNVLECESVKLSEKTIIDIALWRIYFNELDDAFELLEKEASLPPYSESSVLLGYLGLVSFLIFLKEVENNFKSFEEFSWKKVDFNDYQHFESYEKSLTYLENSINIKFNDQFILLYSSISILTNRTEKVGEILTEYQESEGKLDPNALRYSLWFSLRLNNGLKELRILVENKNLKNFGFIEEKFKNGKNFPYWLKFAKNLLSMDPIADDCFLLCVLYFECIDESVTVLEYLLERIDHPYFQNNEEKNKYINVNTEIDLSEEGLAAYLNLKLTENFIWEKICFHLKKIRTSNKCRSDIFLWENRGRWWKKMHFQTISEPIVKITSEYEELIVLKAIAATFIYTPESYLKLKFFSSKFENSTDFTIKKKMKFAFIKDCLNRNETAIIKYFGYNEINENTTIANEQVLNCYSFDFNENSLAKIKLYLALDFKYEFGWDIFLGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ88</accession>
    <name>A0AAD5XZ88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000516">
        <property type="protein sequence ID" value="KAJ3215858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ88"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="28799" checksum="E90DBCE41CDAE8B1" modified="2024-05-29" version="1">MIKDKESASGIVEVVSTQLGEERIIPPSYRPDAALEEAPRVGPEFFPQVGTFVKIIFKNTEVIYGRLMVIDPITNSKILLQTFESEDKDVEDLPLPKSCNFKLVFDNSIKEIFECENEQDHFSPQKKISSTTIIEIFNHYFPLEKVNKIENSLLNNLQQKLISFLREKKFTSYELKDEIYFKFFNNKLDEGMEKEFFMVLEPPYVKKSLLRYFFGKEGEKELGLIKEFITEVENLLEEFRIVYAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZC3</accession>
    <name>A0AAD5XZC3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000356">
        <property type="protein sequence ID" value="KAJ3218995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZC3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="38"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3218995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="15518" checksum="3FF75BB2A9007438" modified="2024-05-29" version="1">MIEFVYGDEASLFSNKEIIANELTGELGYKNLSAGTYLDLKVFILGSLVTGVFGFLINVAGFLQIKVTSPVSHMISSAVRGVIQTILAIMIFGDSVTEAVVIGTVLILTGSSLYTLFKSWEQKSEFRLTQNELNKKDSSRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZN0</accession>
    <name>A0AAD5XZN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PRE8</name>
        <name evidence="8" type="ORF">HK099_006733</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZN0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03750">
        <property type="entry name" value="proteasome_alpha_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000028">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3228108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="257" mass="28070" checksum="81C4ADDF1B38BF8B" modified="2024-05-29" version="1">MADGRYSFSLTTFSPSGKLVQIEHALTAVNQGITSIGIKAANGIVIATEKKSSSPLVDDKTLEKVTMICKNIGLVYSGMGPDARVLVDKARKAAQEYKKIYMEEPPTLILVTEIATVMQEFTQSGGVRPFGVSVLVAGFDEKGPSLYQIDPSGSYFAWKATAIGKNMINAKTFLEKRYNEQMEIDDAIHTAIITLKEGFEGAMTDNSLEIGICYCEDEEFSLPGEAGFVEGGKKIRKVGKFRKLVNEEVKDYLANIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZR9</accession>
    <name>A0AAD5XZR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL32_2</name>
        <name evidence="4" type="ORF">HK099_005157</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000390">
        <property type="protein sequence ID" value="KAJ3218214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_eL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018263">
        <property type="entry name" value="Ribosomal_eL32_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_eL32_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="Ribosomal protein L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00580">
        <property type="entry name" value="RIBOSOMAL_L32E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="133" mass="15564" checksum="FF1CC6EEF92350EC" modified="2024-05-29" version="1">MTTSLNKTPIVKKRTKKFVRHQSDRYDKVKESWRKPKGIDNRVRRRFKGQIAMPKIGYGSNSKTRHLLPNGFKKFLVSNVRDVDLLLMHNRVYSAEIAHNVSQRKRVEIVARAAELDLKLTNAHGRLRTKEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y013</accession>
    <name>A0AAD5Y013_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004778</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat AIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000349">
        <property type="protein sequence ID" value="KAJ3219180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y013"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000102">
        <property type="entry name" value="Actin-interacting protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000167">
        <property type="entry name" value="Actin-interacting protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856">
        <property type="entry name" value="WD-REPEATCONTAINING PROTEIN WDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="184"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="230"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="319"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="531"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="571"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="607" mass="66376" checksum="AD99FC95DC6E02CD" modified="2024-05-29" version="1">MSFKRVQTYASNPNTTRGQAVHLGGDPKGNNVLYTNGRSVIIRNLKNPEIATEYTGHSCNATVARYSPSGFYIASDVQGNIRIWDTVGSENIIKTETKVFSGKINDLDWDFESKRLVAVGEGKDKFGHAFLFDSASSVGEISGHSKVINSVSLNKSRPFRAVTGSDDCSVNFYHGVPFKFNKSISDHGRFVQCVRFSPDGNFFATVGMDQRIFLYDGKSGDKVKELSLSKDTHTGGIFSVSWSPDSKNILTHSADTTVKLWDVEASSVISTYQFSDTLGKIEDQQVGGLWQGDFMLSLSLSGDFNYLDKNKPGKPTRVVKGHQKAITALATSEDRKTIYTGSYDGKIYAWDNGNTKDCISIEGGGHKNQITALCVNENKIFSAGMDDCLKIIDEKTKSFGPLNFSTGSIPKSIASKEDLVLISTLKQELILTNLKGEKVFSQSVKYTPTSVSISPKGYQVAVGADDNKVYLYELKGNSLVDLNTTLDSKAPVTSVSYSPDSSLLAVTDSSKNILVFDVATKQVKISQWVFHNARVNSFSWSPDGQHAASGSLDTNVEIWSVENPMKHISIKGAHLEGVTGVVWLDNQTVASTGQDCMLKVWSLTHHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y118</accession>
    <name>A0AAD5Y118_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphodiesterase</fullName>
            <ecNumber evidence="7">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PDE9A_2</name>
        <name evidence="10" type="ORF">HK099_003167</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="7">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000211">
        <property type="protein sequence ID" value="KAJ3221747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1300.10:FF:000006">
        <property type="entry name" value="Phosphodiesterase 9A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0140">cGMP</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="9">
        <location>
            <begin position="1338"/>
            <end position="1671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="202"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="441"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="247"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="486"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="513"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="701"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="735"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="786"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="825"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="859"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="1426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="1426"/>
            <end position="1430"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="1430"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="1466"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1467"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="1467"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="1467"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1576"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="1576"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1627"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1673" mass="191028" checksum="C1E1CF5F8BD55A37" modified="2024-05-29" version="1">MSTTLKSPPMENPSVASILTYEGILSIPNADEFVDGFSGVLKTYFPNNVHEYGTLLPPDLRQHNYNGRHVTPQVWKDEFKGGQHPNAYEKSYINSSLKTAHTNFDKSKRSSTSSNATVEKSKEISNKINDKKSIETSIKIVKEISKVDKSSISTDAKKKNNLFSKILEIPFFMNLPLPIPNDISKEKLLSGTVIKKKSNLKSSSLNSISGNSTTPFITNTTPNAAKVTSEKKTSSMETLINKRKQRKEFYDSEENKRAETGRGKTGEKSAVKRKYVDSESSDSEAVEYKQTKKASKKPLKLSKVNDKEKHLITFSLPDSFSQKDPIPPDSDLISPVSDKDTIDADKKLVSKKENRKEEKNSGDNSKNVGPSGPGEKVEIDMIKTKSIETPHISKSSSKIVNETEDGKLNEKELYSTSVLSSKKEVSTKSKNFSKNTLLDLKIADKNSGSPKSSLKKELLRGSVSPPNSEVKRQDTQTKSTSGSIKQKSEKSSAVLKKSDIKKSRNKTSPTSKKLFEEKSDDTNGKEMHKDKEVGEKDRAEDDEDGRREFGKEKEEREKERTKEKEEREKERAKEKEEREKDRVRAKDKDEGEKDRVRTKEEGEKDRVRTKDKEEGEKDRVRTKDKEEGEKDRVRTKDKEEGEKDRIRAKDKEEEDRSRNSKSSKSENRKEGSGSATVSSAKEKESVKSSSGKRKPSPSNSDRGESKRKRNEENQRRPSELSSRRSHSPPSKRYSSRRDSDRRSRSPERRSRDERGRYDRSRSRDRERRRSNRSGSKDNLASPRYNGDSRSRKDEKRDSDRKRRDGDDRREYSSSRRDSVTETGGRRSHSKDSRRKSSSPKKKSSPASTKKQNFIRPGPVSSTPEKVSITSNTLPKSVLKLTDYIARKNDGTPPPPPPLSKTLLSTSVTGKNLISTPTPTTVVSILVNSQAVNSPSTPVSTPSQPTAYFISKKLLPIFPQFLEESLPELHLDFQSTARLHKRLGDGLKKENPGNVKKTKEALCHQAACSIYYLKHFFILEQRGLQDIKKRERVMKDFSHPFYSSSTTFVYDRISELRKYKLYGIASVLLQLLALVEEKAVFWKELEIERLSHNHFLNPISSGEKEVQTMMTLMQENRINILRHHSIQRLKSDALSLLTANYSEKIREKYKVIECSPRLNLDEAMKKAVGLVEEFAAENEFSQFCFLKPKPPIQQSNSGNDKSETLMIDPRSSLKEVQGLLRAAAKLNETTSDSLVFKLYNQQGMLIPIGPHIPPNQPNEVYHLKINYAKKLREEALKQTETSATENYKTKEVLDEINEIAEKFQILKAKSEIECKQNVVSVKNEFERIINKPALKRIDDLMQEPSAKQDIFLSQEIEDTLNLSESDLKDLQTTRFDVWKYKTVDEIILILEEIFKNFDLLNIFKIERKTLHQFLRCVSLVYNKNPFHNFRHCLCVTQMMYAILHESEFYKKFSNLEKLTLIISCIGHDLDHPGYNNAYQVNAGTELAIIYNDCSPLENHHTAVLFSILKHDEMNIVKNLSDANSKEFRKDAVNLILATDMGKHGEITSKFKALIESFKIEDENHRKLLLQMIIKCADISNEVRPKVISEPWVDMLLEEFFQQSDKEKSEGLPTAPFMDRQRVTKPSAQVGFIGFVMIPLFELVAKVLPNIDTKFIVPIKEAHQYYKNLLENEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y194</accession>
    <name>A0AAD5Y194_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ccr4 associated factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CAF17</name>
        <name evidence="5" type="ORF">HK099_002696</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000191">
        <property type="protein sequence ID" value="KAJ3222117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y194"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057460">
        <property type="entry name" value="CAF17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602:SF0">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25455">
        <property type="entry name" value="Beta-barrel_CAF17_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="CAF17 C-terminal" evidence="4">
        <location>
            <begin position="248"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="376" mass="43325" checksum="07DC1EF8B9EE5943" modified="2024-05-29" version="1">MKALELINKLNSFSKISARSLISIKGSDATKFLQGLTTNHMPLIESGHGNGLYTGFLSAQGRVLYDGFIYPKLNLSKIPEYLIEVDDRALEPLILHLKKFILRNKIELNNISNEKDVYQIWGPNFTSLYSGTLIDKNLDLLNKNEKFPVGCLIWDKFSNIGMRDPRHLDMGLRVILPKGDIPNLPSDFKQVNRDEYKLRRILYGIPEGVDDLFVNNSLPLESNFDYMHGERGAIWELTIRTYHTGVTRKRIVPVEIFKSTTRDDEILKKTEIEVKKDFKLDFPKSQSDIKLKEEHLMTTKEVTNDQNLKKKKKREVVAGKFCSGIYNVGLALMRLEYIQQTISSNTSELRNNEQILVLEDNNKVKPFSPCWWPKCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2J4</accession>
    <name>A0AAD5Y2J4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2J4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="513" mass="58063" checksum="0CE78199F4AF4522" modified="2024-05-29" version="1">MNSIQSSFSLTDDISNNSSPNLSSLSLDATSSHELFFLKDQLKKNYQNNLSKNLPHHQELKKSATKKWSDILGPADFNTLISHAFSKPRTPMETQIYIKLLYRRLPVNHYSKGIKKCLRCGYNDETIEHAIFECKESFEYWNNVNNLIYSILSPNVLTAKPVKLMDVIYFFPEIRKILNIRQLHVLSVIHSNALFALWSSRSNTFQSDVLGINLYWKTFCMRLKANLEVHHTLAVKIDFQNGYELKKNSSISSSNSSNHSNTQNDILKENYAKAASRLGNGKEDNYSSGFNFSDSPMQLQITQVSGSSGIITPSSSPIAERNRKQSLGSSLNQIINSFGSHELAINDFDFSPVEKASDNNNINIENNCSNSNGNTETLTEGFTGSEEELFFERWGKIVTQEKDENISQFNKPFLNDEKTRLNALPNSKKDGTPIDKACKIKKRKGSKQNLNLTWKEIILIKIGHMSEPKSSPVYTTKARNNPEPVNNSKYLPIFEKPKYPTFQLSTANVVGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSY8</accession>
    <name>A0AAD5TSY8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001802">
        <property type="protein sequence ID" value="KAJ3200972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSY8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="54"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3200972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="160" mass="18359" checksum="C557E7FE5824A716" modified="2024-05-29" version="1" fragment="single">MSRVGSALKLSAKEPETARDSTFIKPRASANVRPSLSNYNKNQKEFTHHLELYLPQSLRCYDVTGRNLTATWIELSETAEQEHQELLKKTNKTLLYQLSKSDETNDGVYTSVYEGAAKRFDVSGLVPLTNYKFKLRVKWEEDENEDAWSTKSIMCEVKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTH5</accession>
    <name>A0AAD5TTH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001575">
        <property type="protein sequence ID" value="KAJ3202408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTH5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="233" mass="26625" checksum="9C4F0CE086A5E93B" modified="2024-05-29" version="1" fragment="single">PEIINDNQKYVDQFIQCILVARLYLFNDLQQKLKTKLTPELWLFVQLFPERYYSHNFFTILVEILRHLKENDLKDMLNSLVQKIPEKLLAIFLDESQLIVDVGSDSFPSKSTPGATCSLLNAIKNSISNEAEKFCFIPTGTGLRIGDVHGEGSKLSSAAKDSKQSLILTVSNVWETPDDIQKYLSRYLGSSFILEKEKACLLLGRVRPVALFLEQCLVCIDTDFEINNYFEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUE5</accession>
    <name>A0AAD5TUE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002176">
        <property type="protein sequence ID" value="KAJ3199158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUE5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011:SF1">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="2">
        <location>
            <begin position="59"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3199158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="144" mass="16371" checksum="33D8DEAC58DD7BEA" modified="2024-05-29" version="1" fragment="single">MGKLLLMQSIKLTTISLIKKQNTFPQTFNYLNNRYHQHTYFSTSSLSLSEAEIPNIQKKIFISDNAAFQLKKINSNSPQKNNFLRITVDSGGCHGYQYLIKLDQNKFDDDIEFEKEGAKVLVDNISLDLIDGGTLDYVDELIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV20</accession>
    <name>A0AAD5TV20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008737</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000999">
        <property type="protein sequence ID" value="KAJ3208360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV20"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004081">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006167">
        <property type="term" value="P:AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006754">
        <property type="term" value="P:ATP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3208360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="28987" checksum="D7D3DBA34EDC1374" modified="2024-05-29" version="1" fragment="single">GWYLPGGRAEQNEDLIVAICRETKEETGIDIEVKGVLRMEYTPSRHGFRLRVIFYAEPKTNNDFPKCIPDGESSAACWITIDQLEQLNEKEDEKAFLNLSLPLRGPEALYWINYVDQGGAIWPLNILAKEKDEVIIIEDPWLHTQKKIKPVSKVSTANTTISATSSQANLQKQQQKKNKVLEVESSTEESDDSKGDTVGNLSSIDSVSGKRSEKSRRRHATTDSEGYSVSEGASRATTGGRRVIEVVVDTSETDAYDWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV21</accession>
    <name>A0AAD5TV21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001186">
        <property type="protein sequence ID" value="KAJ3205671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV21"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="439" mass="50103" checksum="B435A01BFC4D515F" modified="2024-05-29" version="1">MSSLYYRQRINPTKINDTLTRRRVSISDLLDDYESNEAEEVIKFRENLFPQSESMKLSFHSSRNSKSATSSSASTINSVRKSIKSFDSLYDEINNSVTFDFDDVKADDMNIMANLSFNSTKNSKEGLSPSTASGNLINMNNNLDNIVAPVENNNSVNFSIKNFGKKFRNFLNINDNSSTHSTNSKKNIFNFFKNNQPKNISPELPLSESRHVAAGKYNSSKSLDLNSNDRRNFFESSSEADITNNKYKKKINSNSNKMSHNNSNISSSKNIDSSKASKVSHNKIVTSKETDELKHLVYQNKKLQQKKSVPQQSSVPQVRQQNYLNQPVTYNQNLQNKLYLKNDSIKLNKKHFDQSPVLKPRKNFNMCNEKVNANTISDISELKKLRRRSSLPKNFNLTIDTEVNKEKKTEDGAKSGDSDKTLFLKTITYSSWLDMDIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVM9</accession>
    <name>A0AAD5TVM9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001044">
        <property type="protein sequence ID" value="KAJ3207619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVM9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF19">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fatty acid desaturase" evidence="1">
        <location>
            <begin position="242"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="359" mass="41174" checksum="2779BDF9F8BD42A0" modified="2024-05-29" version="1" fragment="single">VDYNFHFNRLKLGAEELFNFALTVDDKKKIFFLIKNCIEEFYKQILQIDIPNSSTEIEAKVTILIFKDETENMKIICLCDTFKENKLPYCKILLGGKPRSLPMVKASQWVLDRVKFDDLVVSPIHEVVLMDDSNDIFEGLTSNFCVLTTNDSNFDPQNAVDFSMFTIISAPQDQVLPGSMISLVSSDKPQEILKKFKIGKLEGRNEFPSFPRDTGFYRDLTKKVGDYFKKTNKDPKDPLPGLWLSWNFQVSHVSPIADFYEKEGEIDEWAKVQVRTSIDYAHGNALGTFLCGALNYQIEHHLFPSISQYHYPAIAPIVMEVCKQHNVKYNLLPSFTAAFKLHLHHLYNLGSEPSKVKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWA7</accession>
    <name>A0AAD5TWA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD repeat-containing protein 34</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">WDR34_1</name>
        <name evidence="4" type="ORF">HK099_001480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001417">
        <property type="protein sequence ID" value="KAJ3203523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWA7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097014">
        <property type="term" value="C:ciliary plasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF26">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3203523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="29702" checksum="634D5EEED9681116" modified="2024-05-29" version="1" fragment="single">MLKEDFQEEIKENYNFNDTKTNVIDIETSWKKEKIISVSSTQTEDLSFKESQFQTITTCNQQVQTVPEKLKSQNFLQDYNRETMLKFLSLVEPLISSQLMNNIRSSAFDGYTVNWEPEIDEISCVHTLKEKRREIDTICTDLTWNKSGSVLGVAYGRYDHESWCTHKGTLCTWNVAMKNVNTEIANFTTEVSSCLMCIAFHPEIPSIIAGGTFNGDVIVWQTNDVDNPILAYSKMEELSHEEPVSKVTWIPGKKHGDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWH0</accession>
    <name>A0AAD5TWH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000621</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="JADGJW010001150">
        <property type="protein sequence ID" value="KAJ3206122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWH0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF6">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3206122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="492" mass="55399" checksum="C54131BE2F351D3A" modified="2024-05-29" version="1">MTLSSVEAADIENNEQFSSCVYGFARQHNPTHEIPEEEMPPTVAYAMIQDELAMDGKPCLNLASFVTTYMEEEAIKLMTENMTKNFIDYEEYPATIDIHNRCVNMIARLFNAPFTENEEALGCSTIGSSEAIILSVLAMKRRWQQKRKAANLSTDSPNLVMGANVQVCWEKAVNYLEIEAKYVYCTEDCLVLDPKKAVELCDENTIGICLILGSTYNGEYEDVKAVNELLEKKCADTNGAVDIPIHVDAASGGFVAPFINPELEWDFRLPRVVSINVSGHKYGLVFAGVGWAIWRSKEYLPQNLIFTINYLGAEQNSFTLNFSKGSSQVIAQYYVLIRLGKSGFRAIMRNLQSYSDYLGDILEKSVFKVVSKRNGEGLPLVAFKLKEKKHYDEFDIANKLREKGWIVPAYTCPPSAESINILRVVVREDFSKSRCNLFLKDIAAVVKYLETLEKSSLKVIRTHTMSAKDRWGLVKNVFKIKAAHKISTHGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWH6</accession>
    <name>A0AAD5TWH6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000709">
        <property type="protein sequence ID" value="KAJ3213456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWH6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="113" mass="12844" checksum="E36355EBCFCA03AC" modified="2024-05-29" version="1" fragment="single">WPIRVGQGTYNLPYNRKGKGTIACYKKDHEDDNCRAYSVQDKSNVRRIGKDEVTKTGVILGLMQPLLGHSFYSFKESKSRLDTKRAYTTRSKAKELVPVVGQPAMPKDYETIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX04</accession>
    <name>A0AAD5TX04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">H3F3B_2</name>
        <name evidence="8" type="ORF">HK099_003380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002217">
        <property type="protein sequence ID" value="KAJ3198979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX04"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000001">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="7">
        <location>
            <begin position="44"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3198979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="129" mass="14440" checksum="2DE6F5D93DA75EBB" modified="2024-05-29" version="1" fragment="single">MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKADLRFQSSAIGALQEASEAYLVGLFEDTNLAAIHAKRVTIQPKDIQLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX78</accession>
    <name>A0AAD5TX78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000702">
        <property type="protein sequence ID" value="KAJ3213510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX78"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="126" mass="14072" checksum="2C50B9E535024F9E" modified="2024-05-29" version="1">MKRKYRIEGYNAIHDTVNPPKPAGNKLDASKGMENSKKINKNCNSEEGANLSMQNAKEQVNRAANTVYEVANKGLEKTKEAVSKGVDYTKQKTGVDANQEPKRVGEDYNIISDNSERAHVIEKFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY80</accession>
    <name>A0AAD5TY80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Autophagy protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ATG6</name>
        <name evidence="4" type="ORF">HK099_001701</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001505">
        <property type="protein sequence ID" value="KAJ3202899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY80"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6 BARA" evidence="3">
        <location>
            <begin position="78"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="3">
        <location>
            <begin position="168"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3202899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="209" mass="24621" checksum="06C647DDF1F8D55D" modified="2024-05-29" version="1" fragment="single">LKDKEENALNILNELDKEREQVEMELSSVLLEIQELEAAEMEHFQQLNKLELEISEEFEEKQWLKFKNYFNSRRLEELEKTNVYNDSFRIWYDGPFGTINGLRLGRLPTENVEWSEINAALGQTLLLLYSLAKKLNFTFQGYQLVPLGNFSRIDKIDEHGGKSRYDLINNDKIGDKSIKFTSDESWTKALKYTLIDLKWILTFAVQNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYC5</accession>
    <name>A0AAD5TYC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein 53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VPS53</name>
        <name evidence="9" type="ORF">HK099_006320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VPS53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000538">
        <property type="protein sequence ID" value="KAJ3215505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYC5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.110">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 53, C-terminus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039766">
        <property type="entry name" value="Vps53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031745">
        <property type="entry name" value="Vps53_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038260">
        <property type="entry name" value="Vps53_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007234">
        <property type="entry name" value="Vps53_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16854">
        <property type="entry name" value="VPS53_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04100">
        <property type="entry name" value="Vps53_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps53 N-terminal" evidence="7">
        <location>
            <begin position="43"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Vps53 N-terminal" evidence="7">
        <location>
            <begin position="127"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Vps53 C-terminal" evidence="8">
        <location>
            <begin position="616"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="765" mass="87999" checksum="FCC4CF6D9CEA9693" modified="2024-05-29" version="1">MFNENLGYEKIQLSNELDIALNNFIKNDDLGNFAFKIYDHSSDFSITEYINEIFKTEESLTTIDVVLMKLRTQIIKIDKEINSNLTNQFDAGQHSEQELASVKKNISLLYEKIKTMKENALKSESMRLQMIVLAMNQLKIIAKNKQYSDTSQLLLAIKQLLINFENFKNVKQVQTIIENMNRFEADLKKQIFMDFEESFVGGTLRTPAKKLYDACLVVDILHKDEKKHLIDWYCEMQLKDYIQIFRNNPEVSGLADVSRRYAWIKRLLKTYDEEHATTFIQEWKVPEILCEKFCLVTKKDITEVLNKSGANKTIDVKTMLVSLQTTMEFEAKLDKRFGIKDYSETGFQETAIDPSSKFYKIISSCYAPYLEYYIESENKALSEMMQQYREQPIETSDQQANEDSVLPSSTDLFYCYRQTMVQFSRFSTGKPFLDLSKLFKKWLSIYSELLLSKLPREDLKKISEEEIRVTCVIINTADYCTSTTAQVNILYQKCYTKTNGLISWKRSWQKKLMWSLRLFVTSSALKILVKCIGSSVDPALYNMSKVPWGSIESVGDQSEYITMIAQILSQLVGTVKKSLGGPKFFKTFCDKFADALLVKFEANIYKCKPVPEVAAEQMLLDTHALKTILVQMTNIGSQNNVQPPSSYTKILTKGVLNVEKLLKTVMIPSDPAEGLIDRYLMMYTGDVSVSGFQKILEVKGLRRGDQQLMIDVLQNKLANLGPAAEILYNKSTNEENKKSNADLLGQNEKVSNKLKEDISKFFKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYE1</accession>
    <name>A0AAD5TYE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Actin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005743</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000461">
        <property type="protein sequence ID" value="KAJ3216768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYE1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10208">
        <property type="entry name" value="ASKHA_NBD_ScArp9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="42168" checksum="43DC97E449D64F32" modified="2024-05-29" version="1" fragment="single">MNYVVIYPSIMPKDPCLILSVGSFNTKVGIADHLEAPTTVFNTCLAKENQTQTFIFGQDLKNIPESEKNWPINQGIVQDWDSLCEIWKHILVHKFNVIRMRNDKPILVMIPSYWSKTDIERLTQIMFEYLNVPGLYIAEQPLMAVYGIGAVTGVVIDIGHETTDITAVLDTTINYYSRQTILIGGRHVEEYLLELLKKDEKFLKEYGKQPDINLARAIKESSICEVFPSLEIVKSRLGQNEIRKEFEYDNIKFSVGSARYECVEPLFDSSLIGKDYLTLAEALTMTITSYTEPEKRLSLWESLILTGGVSQLNGLQNRIEEEVKPFIAASETSHETQPKEIRFQKIPEYFTVYKDIPSEVTFLGGSIVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYJ8</accession>
    <name>A0AAD5TYJ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_008606</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000966">
        <property type="protein sequence ID" value="KAJ3208986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYJ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="118"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3208986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="642" mass="72411" checksum="5F907FB18564D512" modified="2024-05-29" version="1">MTNLVSNQQKLSKRASFIRGKTAEKNVTYSKIKKGSKFLSNTVDFNPCFFLAAVATEGLQNARNKTVALVSAISKECRSKNEKFRDSEFDLQKDPKNCIFSLDDNEFDATKVPNGVARVTSIFENPKFYSDGVNHNDIRQGADGDCWFLSALSIASNIPKVIENLCVARDEEVGVYGFIFFRDNEWVPVIIDDQLFVYFDKLQNAPPLIKNFFVGREKMYDKLIAGSNRLHFSKCRDSNETWLPLIEKAFAKANGDYNCIEGGQTGEGVENLTGGIMSQIFIGDILSKERFWNEELRYCNADRLFAVQNMSLATNDEHQGLIHYHAYGILKTCEIKGKRFLLIKNPWGESEWKGAWSDGDANWDSEWIQLLDHKFGDDGAFWQEYDDFLKSWTSIDKIQLFDNSWTLVSNWLEISPSFPSSYGDAVFKLEIKTATKACISLSQSDAFRSTTCDAFLEPGIYDIIVMVKYELNSSPSIKSLLQSTEAHDIKKFTSTASSYEFSRSKASNYVPFDIVGIGRKLLESNGQVKVSKSKVTKGVRTTKNIPKKSATVSDNENCSTEGEGEIIKVATQHDLSLNEIEETDEIKINKQFGHPTVVIGLRVYTKDKEMELTGLHGDQCENLEILEHANVPEANEIHLFGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYK3</accession>
    <name>A0AAD5TYK3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005895</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000480">
        <property type="protein sequence ID" value="KAJ3216407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYK3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042135830" description="Aquaporin" evidence="11">
        <location>
            <begin position="19"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3216407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="47194" checksum="49AD266C38C5B8CF" modified="2024-05-29" version="1">MSTKLISVVVLFIASVAATPALMCPQVMPSCDAVRCASGTCKVFPQTKTSCAQVKCVEDTLVCPQHLPCSAVRCASGYKCENIPQTKTSCASAKCVKRFQKTSEFSEVKDYSNEDIESKGTFANSPHSDTTDNGHLLGEREPEIRPLSLNPMDWYRDIKSEYEQFTWAMTEKKRVLLRAIFGEGLCTFLFLFTVMAASVNNGRQESPENLVVGAVCVGFCSIAYIYSFADVSGAHFNPAVTFGTIIMGKVSVKKGLAFIGVQIFASILATIWVMAVFPKHLPTGITVSNALVVNLDANTKLVNAFFMEVTLSFILVYVIFATAFDTVDTNPVKVDGGKGAVGNNLTIYTTSGNSKAGFAPIAIGFTLGFLGLLGGSVSGGCFNPARAFGPAIVADSWDNHWIYWIGDFAGAALAGWTQSFFAHKPTHKSAAAPTNKSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYS5</accession>
    <name>A0AAD5TYS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005738</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000460">
        <property type="protein sequence ID" value="KAJ3216803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYS5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF20">
        <property type="entry name" value="[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase N-terminal" evidence="10">
        <location>
            <begin position="48"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="9">
        <location>
            <begin position="241"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3216803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="349" mass="39461" checksum="B72E21F0AE6A437F" modified="2024-05-29" version="1" fragment="single">MIEKLSKISNKTVNRFLHRESVVNLANHPIWNSSALVEKYSRQPIVPVTLSWMRELGETHSIRESASYLHKELPKRLARRVKALQNLPFIVGENPYIKSIYHLYSASFEKLRTFPPIDSSEMEDLFSDTLLELVETHQDVIPNLAKGFAECGHYMSKGDRTKFLDGLIHARIGLRVLAENHLALNDEDPEWAGVVHKNFKPALLISSIGSYCQNLCRMNYGTAPEFVINGQENATFPYIPVHLDYIMMELMKNAMRATVEHSQKIGRVEHPDIEITVVSGKEEICIRLRDQGGGIPSHCLPFIFDYSFTTVPKIEEEDLDVFSAQSRMQMISSSGGPMAGLGFGLPMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYS6</accession>
    <name>A0AAD5TYS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000747">
        <property type="protein sequence ID" value="KAJ3213094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="97" mass="11217" checksum="788C8D17452D03C8" modified="2024-05-29" version="1" fragment="single">MKIKSTKDSVCSQENLSIEELLNKVTNLFDLINGSKPTKVTEINKNYIYLCPMISCNKVFKKTSSLKNHFISHGFAQKYTCHCGKSFYRNHDLSRHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ52</accession>
    <name>A0AAD5TZ52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lebercilin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005476</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000428">
        <property type="protein sequence ID" value="KAJ3217435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ52"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028933">
        <property type="entry name" value="Lebercilin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15619">
        <property type="entry name" value="Lebercilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lebercilin" evidence="3">
        <location>
            <begin position="125"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="588"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="683"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="799"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="212"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="808"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="822" mass="94810" checksum="D5CD2669C2006FB1" modified="2024-05-29" version="1">MMEFDDYHYDFEMEEKFKSKSPSILEESTAIKVHGLKGSEVSSINEFQTSNIDPPLLKKKVITHKTVVVSKNLKEKLIPEKKKEDKKKHKKNKSVYNGDEYAKTVHAGQFEEIVKAIKVADERKAICKKLIAEMKLLKLESQKKDKIINQLQKENKQVPEIIHSLSEEARVLRFEKQGYLEKIKITEKNSQLNIEELLSLREQVNKLNTIIKSKKLNNVEKLMEELKNLKDQNEKNLTEISNWQRKATHIEHEKGMELREVRQKLQKALKENSLFHSERDGLIEKIKSKDKQIAALSIYTLSTKKTQQKIIETLPIQQIYSPLPPQLLATEDSVTFEAEILTGLKQNEPDPSQKLKKNENETKQNLQEVTRSLEAKNNKIINDPHVEKSTTTTAQFTKNFAKPILNKIKNEDLSISQQSVDYNTNQDFKIEKSNENNTFKPNLFKPVMGKNKVELQKEKHHVTEVTVETTVEKKEFDTEEDSEFHFKNKDNFKKNDTTVENNNEEVEKFTIKSTADSISSFGSSNTCSSPTTNGLQETTFQQNLKLKIKELQTKLQNLEGIKINSFTDLEEKAKLKLEIKNLEKSLLTSGEGNEQVDENTLQSTNNAPTIENRLDFLETSTNQKSKKADKEEEKFNSSQIPTFGRRKKREELKKDIFASSDSLTNSQKQNETALQKSKISNSSLSFLNSKPKSPPTNNLNTSSGYKPTFLNFNNNTFNNKKIASTESLIFSNDNLNKKKEDEICKPSFFNTNQKSLEKTKKENVEEDFSYNKESSKQSLVKEEIEEELSKKEEFKYGNSLDTVHDPYQDDFEAQDDLDAEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ99</accession>
    <name>A0AAD5TZ99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000836">
        <property type="protein sequence ID" value="KAJ3211411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ99"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="173" mass="19538" checksum="B560E3F312D3E3CE" modified="2024-05-29" version="1" fragment="single">MGLDPLCNGCGVKWKRARILQEYPHPHSLKNKKNKKMDLEKPKKQLPKTKSKRRSIPFPEEAENNKHIITASSFNSISLVNNFCSMDDDINFFNSPNSVTNNSITATAIALTEVDKIAYFKAFLESIPADRITLVCSLLVEDNPTLKTKLANGEEVDIKFQDLSESAWKKIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZB8</accession>
    <name>A0AAD5TZB8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">small monomeric GTPase</fullName>
            <ecNumber evidence="1">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAP1_2</name>
        <name evidence="6" type="ORF">HK099_005163</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000391">
        <property type="protein sequence ID" value="KAJ3218204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZB8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032486">
        <property type="term" value="P:Rap protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04175">
        <property type="entry name" value="Rap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000182">
        <property type="entry name" value="ras-related protein Rap-1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038851">
        <property type="entry name" value="Rap1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="183" mass="20844" checksum="ECD3EE3CB13E970C" modified="2024-05-29" version="1">MREYKLVVLGSGGVGKSALTVQFVQSIFVEKYDPTIEDSYRKQVDIDGQQSMLEILDTAGTEQFTAMRDLYMKNGQGFVLAYSITSQATFNDLVELREQILRVKDMDKVPMVLVGNKCDLEDDRVVSKDQGQTLSQKWDCTFLETSARKKVNIDEVFFDLVRQINKSMPEKVCSSLTEFLLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZH4</accession>
    <name>A0AAD5TZH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000630">
        <property type="protein sequence ID" value="KAJ3214345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZH4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="689" mass="76932" checksum="72767F34281E4069" modified="2024-05-29" version="1">MNSLPKDNLLAKETTSTNNPPSVDFQPNTILQPNKPTLSIYGSPYHQVNSNLSPYTPFSTQANNPFNKPNLPPQGQMYFHNPRYYESPLHSSTVKLDDNTNSTAPHSASLSSTKPQTRSQSISKATQDLKKVNFNSSQLTNFSIPPLASHLSAANPKLHSANLTEKTSDILILSGTNHISETKLITKAIEDKSTVMTRCSEFNENIRKYLYNGDSNGYHLVNILKKSCPELSLEDSTINQLQKNLKQLPEFNNPIPSLTKVSLTDPEKGLELQTNVPIKSIPISDLNLGKSNTEPNFKPSQEQSIPFNNADAEFQPSLPSNENANLVIDKKSKIESSNFSDSKVQNNISDTLELETPSSTKASVREQGVNNEESEAEGEENEEEDDGEQEGGDTKKENTKSRPKRRRNASFFGRRKKKAKKNTANEEVKPTNKDENNKDDVAIEEDVDVLEIEKGSPVEEKSNSPPPVQRAPRSAPTNNGRERMLRSKKTADVVHIELTQNKATFEASKVKPVNKGPSKPISTGRKLTSKSPPGSASPKIKSTNKTLKKQDEEEILVKKVFKFDALTMAANIPELDHKYTEFGMELQNGEKSYLVTNESDLKKKFLPFSEEEVQFFEIGLKNYGKNFPKILENEFRQGYVNLLKREIEEEIETEKNGLNVDPEQTSKVLKKSDSSVSYAAAQLDIIFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZL0</accession>
    <name>A0AAD5TZL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Plasma membrane t-SNARE, secretory vesicle fusion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SSO2</name>
        <name evidence="10" type="ORF">HK099_004952</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000367">
        <property type="protein sequence ID" value="KAJ3218719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZL0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="80"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3218719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="209" mass="23509" checksum="B3AC2911D8354AC4" modified="2024-05-29" version="1">MKLTEQKSLARKLIEVAKEYQNIQQSAKTQYRGQLERQFKIAKPNATREEITEALDNNSGGNVFQQQILSSRVTDQRRILDQVQNRQQELNKIEQSLVELFQLMQDMQMMLENQQTMIDQIETNIEDSSTAIEYGSKELTKATDNARSARKKKWIIFFCVLILLIIVGLVVWFQFVAPLVNAANAANNGNGSGTTPVTTTAAAASPTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZL3</accession>
    <name>A0AAD5TZL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein O-GlcNAc transferase</fullName>
            <ecNumber evidence="3">2.4.1.255</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007706</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.255" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000773">
        <property type="protein sequence ID" value="KAJ3212570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 8" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="700"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="734"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="10">
        <location>
            <begin position="885"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="10">
        <location>
            <begin position="1186"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3212570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1507" mass="172293" checksum="80D097228F16B55A" modified="2024-05-29" version="1">MSILMHEPIPVTSEIQMQQSLTQNEPLREGNYSKRDRRDSASAFPYRKHNPNRISQSNIIPYNSVQNTENTLKRNSTEILPAASKRNSIPFFKLSLEDHIQQTNLNGNMGISQVTSEPIQQQQPQLFKNNNNQIQQLQTTTLIHSNATLPERSFSLSGFHHTQNNLFNAIENPRIKSIPSDELLHRRHSAYHGNEISNITFNNQQHILENKMSGQYPNHSFHFQLNHNENNTVFLQHLQQSQQFFSQQQSSFFTQNLLQHYANPPSFHNFAANITHIPNQYYAAGPVVFHGLPIPSNQQFSIGGIVGTANNVIPGTTAIGYSSFVQNPTSPFDSASQELINRKEWFESLLRLAHQKYNSQEFSGALSILQDLYNLNQHHLPTLLLLGCTCYSLGLHNMSIFYNNLILNIDSNFAEAYSNLGTTHRALSNQNLSQQLAECRNINLPPNLIGKSNIECSEYYYRMAIQIRPKYWDASINLAGLLSSQSRHKEAIDVYEAIESLVDDLSEQEKIFDLDKGNKSDSEVVSVIMELEKRRSQLHYANNAGNSVVFTTERRRDLYFAKGNLLYAMNNIQAAKKEYFKGLIAVGLDIGSVFANSIHGTLPISSVTPQLALAINQKNLNTPSNDPLYHPTTSSILQTLAKIFQDFNLPALAVSLYYLSLSIFPTANTCNNLGILLASHRLQESIQWYECGLALDPQHVHLYTNLGSALKDRGQINEGISCYQQAIAIQPDFFIALANLANVYRDLGRVEEAVDLYRRALQIKPDFVEAFCNYVNSLLFICSWENRDQNLQKIKEVVEKQLKDGIAIYPNAVPTVLPFHTFTYSSLSSWMVREISRRNADRVTWNVKSSDWFPGFPKKPREVLLDYNGDVSSVPKNVFENSLHYPFPYDVSTEPTEFIHVGYVSSDFNNHPLAHLMQSVFGFHDRSKFRVFCYSLSPTDNSTYREKIKEESDVFVDVSSWGLKEIVERISLIDKIHVLCNLNGYTKGGRNEIFAARAAPIQMAFMGFAGTMGAGNIYDPENNGPNQGVAISKDGKDRSYFEALESRWIDYFVVDEVSCPRKLVCGEPLSDEEVLFENENQQFISPQGRAGLISNLDDRNRVYTERLIYMPESYFVNDHAQGFREQEDTEVTRLIKAVYHSEDQPGNLKSSDIWPDEAYLSNAERLLWRTEEIRRLKMRNEVFPNIREDTVIFANFNQLYKVDPDIFYTWMNILKRVPNSILWLLRFPPAGEKNLRKLAEEYAGVEVAKRLIFTAVASKHIHIHRGRVADVFLDTPECNAHTTAADILWSGTPIITYPKYEFKMCSRVAASICYATGSWDQRDSRNFKARMQPGGLNLPLERLREKTLLGHHMVVNSYSEYEQRAVSFGLGIKWGWKRIGSRNDNGRPFSDPVSNPLKSDFQNHPVPFYPNTQSPLFIYVPSGTAVDLRRTLFLNRDKFPLFDTKRWVYNLEKGMKLAVKKFYKDWKEFKTFNKNEFLSLPTKVDESGSFAQSKCLWIKDITDEDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZM9</accession>
    <name>A0AAD5TZM9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000389">
        <property type="protein sequence ID" value="KAJ3218252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZM9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042009107" description="LysM domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="22782" checksum="94394DD2873837BC" modified="2024-05-29" version="1">MSEVCLSTSLALLPNILSACAISEQDFDINVATLEKFCIPGSCNTEWAKYFDATRAACPNVSSAGQLTPETCCANKQACVDAVKAQTAPQPGGQPGTGLTDPVPTGVCKSHSVAQNETCFDIAKANNLTLPEFEGFNSDVSCGPTLQTGSIVCLSSGSKPSASPSATAIGATTSASATASAGSSATSSSASATATSTAASGDAKSSAKALNKSIFSLAVMVVFSLCIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0R3</accession>
    <name>A0AAD5U0R3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000460">
        <property type="protein sequence ID" value="KAJ3216799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0R3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000117">
        <property type="entry name" value="Monoglyceride lipase, putative"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="3">
        <location>
            <begin position="26"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="3">
        <location>
            <begin position="312"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="795"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="681"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="802"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="823"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="983" mass="111396" checksum="956ECBBEF0850A29" modified="2024-05-29" version="1">MTIKEEWVLKNNTQIYYKTWVPEKKVIATVTFIHGLGEHCSRYDEIFNHFSDVGIKVISFDQRGFGKTARKNGILGHNEGLQTLFSDVRDADNKVKLAGVPHFIMGQSMGGGLALRYVIQNSKENFAGVIACSPLIGAGKASAVPFWKRYPILGLSYVIPNFAIANPVKSSFLSRNLECCNKYDEDPDVHPYISFGTAANIVLSGEELALNGWENFKTPILISHGSEDVLTCPIASKRFIEKVPIEDKEFWQMDGWLHELHNELECQKVFDKKNFMKRNNKENSNCIIKAEYVIVDDGFSLYFRYWIPKVRTKATLTFVHGYGEHISRYDHFFSLFSENGIKVGGYDQRGFGKTVKLNGIYGHNYGFENVLNDISLANERIREKEIPHFVMGHSMGGGKGIVLRWCIEYGENIQGCIVSAPLINFGSIVPKLAAWQKYLVYFLANFFPTYNLRGEGGGLGRYCTRDAIFNEEAANDPFLTSKISLDMFSQLLLNNDKLLNDGAENFNIPVLCVHGTSDVITCPNTSEEFIKKVPVKDKEYFKFDGYYHEQTGETAESSPNVATELVIQPEAAYMDSLFNFHADSSQSDIFQQDQEVRRDITSVSHNEMQNYFSSNIDTCTNDESSLSHEIRSSGIGVDIGNDRFARINSSVQNSSLIGASFTAGVNRLLELDVDNLYGTMLDDLIQTVEESELSIRRTQNRIMELEERLELEIRMAEQMGLTGWTSDNELDEVLGIITNLERLPTEYHNRQRITASGEEQPERSALRNRFALESLPILPNEIVLRQQEAYERDSRALRGMTRGTNETSEFSEYTSGPAQYFIDNEDESDSDRDEGEDEDNIDERLIQTLFQLHAHHQRSLSNRNHVIENQNSQHYSASSEGNKRLNQELIFFLANEEVDESFLLLNMLVQPLIDRNGDGGEELLKFGLNENGEELVNHAVADGELLKDTLLGGIKHHNNLEENKFFLKTNSFLKLKDGSCVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U117</accession>
    <name>A0AAD5U117_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 13">Aurora kinase</fullName>
            <ecNumber evidence="1 13">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ARK1</name>
        <name evidence="15" type="ORF">HK099_004157</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1 13"/>
    <dbReference type="EMBL" id="JADGJW010000289">
        <property type="protein sequence ID" value="KAJ3220584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U117"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032133">
        <property type="term" value="C:chromosome passenger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051233">
        <property type="term" value="C:spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045143">
        <property type="term" value="P:homologous chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044779">
        <property type="term" value="P:meiotic spindle checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032465">
        <property type="term" value="P:regulation of cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090266">
        <property type="term" value="P:regulation of mitotic cell cycle spindle assembly checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902115">
        <property type="term" value="P:regulation of organelle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072479">
        <property type="term" value="P:response to mitotic cell cycle spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14007">
        <property type="entry name" value="STKc_Aurora"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000235">
        <property type="entry name" value="Serine/threonine-protein kinase ark1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="13"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="80"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="129"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="12">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3220584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="30152" checksum="25090904FD173731" modified="2024-05-29" version="1">MGEENKTFNIEDFDVAKALGKGKFGFVVALKVLFKNELQEYRGEGQLRREIEIQSHLRHPNILRLYQFFHDKKRVYLVLEYAAQGELYRHLQKVGRFSDRKASIYIYQMTTALLYLHQKHVIHRDIKPENLLLGAKGELKISDFGWSVHTPNANTRRTTLCGTLDYLPPEMVEGKNHDASVDLWCLGVLTYEFLVGQPPFEDTESKATHKRIVGVDLTFPEYISSEAKNLIKQLLQRNPEDRLPLNEVLLHPWITKYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1K0</accession>
    <name>A0AAD5U1K0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[RNA-polymerase]-subunit kinase</fullName>
            <ecNumber evidence="2">2.7.11.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">KIN28</name>
        <name evidence="16" type="ORF">HK099_003806</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.23" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000254">
        <property type="protein sequence ID" value="KAJ3221068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1K0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052742">
        <property type="term" value="F:phosphatidylinositol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046488">
        <property type="term" value="P:phosphatidylinositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07841">
        <property type="entry name" value="STKc_CDK7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000097">
        <property type="entry name" value="Putative cyclin-dependent kinase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037770">
        <property type="entry name" value="CDK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF0">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="5"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="PIPK" evidence="15">
        <location>
            <begin position="428"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="382"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="11"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3221068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="574" mass="65210" checksum="7C8936980F67667C" modified="2024-05-29" version="1">MAEKYTKDIKVGEGSYANVFLGTEIATGRQVAIKKIKLSNFKEGLDISAIREIKILKELKHQNIIELIEVFSSKTNINLVLEFLQCDLEMIIKNKNVVFSAADIKSWMLMTMRGIRHCHKNYYLHRDLKPNNLLLAHDGQLKLADFGLAKDFGDPFRPLTSNVVTRWYRAPELLLGAQSYGYSVDIWAIGCIFAELMLRTPYLAGETDIGQLQVIVRALGTPTEADWPDIKSLPDYYDLPYFPRNSLGSLFTAAGVDALNLLEKMLVFDPLKRISAEEALRHFYFTNKPYPTKPHKLPKDVGGQTHQYNLKKQDKNNANNMGNTNGGNKEENLPVKKESSMLKFKIGGKRKVENTVDGEKVEAVKGKLHGENHEAPILRSQSLPTLSPKGDLLSPNNISKKEPLKLNNEPHSPANSQSFKVLIGNPVTEGHENYMLMYDMLTGIRISVSRNNAKEKRDLIDKDFSSSHKLAFDQTGNELTPTSKYHFKFKDYSPMVFGNIRDIFKIDASDYLSSLTGKYVLSELGSPGKSGSFFYYSRDYRFIIKTIHHGEHKFLLKILKDYYQVKFIEGMFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1U5</accession>
    <name>A0AAD5U1U5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional AP-4-A phosphorylase/ADP sulfurylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">APA2</name>
        <name evidence="2" type="ORF">HK099_006982</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000640">
        <property type="protein sequence ID" value="KAJ3214219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1U5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP:ADP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009163">
        <property type="entry name" value="Ap4A_phos1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420">
        <property type="entry name" value="AP-4-A PHOSPHORYLASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ap4A phosphorylase 1/2 N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="137" mass="15820" checksum="D608FC468A4D4807" modified="2024-05-29" version="1">MFHLTKKTFESAKSNKSLIFTPTVLHIKEEDSVKFHIRLAVSLFKKPSDGLNRSLDGKKPNPFLPFDKNLFIAENAHHNFLLNKFSISPYHVLITTKEFQSQLENPDINDFQTAWDFLSQSETDSAVLNYMCFYNCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U258</accession>
    <name>A0AAD5U258_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MAGI2_2</name>
        <name evidence="5" type="ORF">HK099_003310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000219">
        <property type="protein sequence ID" value="KAJ3221614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U258"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10316:SF40">
        <property type="entry name" value="LD27118P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10316">
        <property type="entry name" value="MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="389"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="131"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="326"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="441"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="466" mass="54158" checksum="814CDA90D0361A8C" modified="2024-05-29" version="1">MDNLAYTPIAINSKIETEEVLGPLPQNWEKAPWGKTNRHYFIDHNSKSTTWVDPRTYDLRKHDIRDIVAGELPYAWEEAYDEQVGIYYIDHTTQFHFIDAPWEEHVKEQVLQLQAAKVPLESEVLSNTAAVESINIEEQLENERLKRLEIEEAELKYNTLHEERTKIELQIKELEEKINMINSESPEEVSQEDQEKVKNLKIELSQLDVKIEDERKELELFNNQHEKLKREIEEYQLKIKELNSVNERLEQNTNALIEGNREAHDGINEMRQMIEAEALQRAALEDYIKQLKSEVVQLYDPNAVPSTETETKPAHSDAPLPEPGSAEEVELLNERLEKEHKEKERLQRITKALEEERTKAHDENESHVHHLPTWVKDLDINNEDFNQSLSGKVGSEKSVAASQEIIVEHDTGNGEEESAEPENEKHEVENHVEEEQTVGAETHEDSEVKQHESEQLQVEEEHAEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2H5</accession>
    <name>A0AAD5U2H5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000303">
        <property type="protein sequence ID" value="KAJ3220439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2H5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052438">
        <property type="entry name" value="Chromatin_remod/trans_coact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15572">
        <property type="entry name" value="GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15572:SF0">
        <property type="entry name" value="GLUTAMINE-RICH PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1066" mass="119261" checksum="9338985371E55A44" modified="2024-05-29" version="1">MVSANQSLPPRRLPGNGPISPSYQQQQQQIYYQNQMQQQQYNHPQNQAPSPNQHYNQNHNTPYNPPMQHVAANHNLPPQHPIHLPQRSSVYNQPLQSQHVYSQQQQHSYQQSISFNSNPQISVATKKLAQSNFQHQQFMNQNHIIIQPQQYGQQVVLPPRNVILPPRSNSVQISQRPISPGFVPPPRRFPPQQSGPSGIVPPRAALPPRGVSKTAVATNLPAYSAADNPPMYDALSLGHSSNEMSPTSPTKKLYIPSRTSSVTRVTPDDLMNQGQISFVKNNYDEAIQRWSQTLEGIASENDLFKEGKCLSNIGCALRVQGKHSEALDYFNIAFEKFSRYLVESKSRIGGLKNFIWIEIVLRTLEIDEVKYNFTNITNFYETRALNRSSSTKSAGSTTSSSTANSNGVFVGDPAFGPPIVVAFLNLVSNIGNINFSLGSFEEAIKWHENCLRLVDAVLEEFPLPVGFDPPAAKSNSEKSTTSEVPIKKNLKKLRSNDSLGHDDEALFYQVRASSVLAFFSSQAPSSQSSRKSSLVSAVINHATQYEAVVSANHGDYSKSLELHERSAMKFIDIHDTYSLVKERGNLGCIWIDIGKSMNSVHWLHNLQKHLKLFPDTDRLINSPVIEKTEIFWGPPLIDGLNANLFEDLDINTTVSAGSKQIGKGIDILDNMLEKSKQVGDWMGIMNCCLNMAIGCTLTQQPFLALYYLSRTVHVLNENYELSIGSLSIPAYFEINIFSVLTQTLYLIVRMQATSDIQFFNSENVDSPQNPQTLNNILLALGIDTIDASNLNSDTLSYLITILIDKISVFQSINSPMTINLGIEKKSFNSLQKKKSISLLTLGKLQFLNGVSDKHPLNDTTPLDLKMEFVSKAEASFKQGSTLLQEVLKVGYHTEEELNESFLSSIKRLIEVEGESFVVNSQNNLTLVSSTVASFFELSLDLILISLNKRTSKFEPLQLLQFFQNNSRYVLAEDLTARTLNIYFEFLFKLYEHNLGLCSSCINEILNFGKNIEKVEVGGEEEFEEEEEVKVNEELVPVSANGVGLQYKDDPFGKGVICFPCAHFEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2V0</accession>
    <name>A0AAD5U2V0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Glutamate pyruvate transaminase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Glutamic--alanine transaminase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Glutamic--pyruvic transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">HK099_004586</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Is probably involved in a pathway contributing to genomic integrity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the IRC22 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000329">
        <property type="protein sequence ID" value="KAJ3219730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2V0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1970:FF:000001">
        <property type="entry name" value="Alanine aminotransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000012">
        <property type="entry name" value="alanine aminotransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045088">
        <property type="entry name" value="ALAT1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005595">
        <property type="entry name" value="TRAP_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751">
        <property type="entry name" value="ALANINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751:SF29">
        <property type="entry name" value="ALANINE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03896">
        <property type="entry name" value="TRAP_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="662"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="20">
        <location>
            <begin position="106"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="686"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00077894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00078532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00080525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3219730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="736" mass="83583" checksum="7CE8A88957C0315C" modified="2024-05-29" version="1">MLATKISRMNSKLLTKIPALNLSSNKTFTLDKANQQVKNVNYAVRGELAIRAEFLRSELNKTSHDFPFQYITNCNIGNPQQLNQKPITFFRQVLSLIDNPDLILEENLHLTKQLYPPDAITRAKTMLAALGSSGSYTHSQGIPLVRENVAKFIEERDGYPSNPDHIFLTAGASPGVQTVLQTLIEHAHVGVICHSALFISNIHFQIMIPIPQYPLYTAAIDLFNGTAVPYYLDEEDSWGMSIAELKKSIKQARELSVDVRALCVINPGNPTGQCLTERNIRETIAFCKEEGLVLLADEVYQKNTYAKDLPFHSFKKVLRSMGDEYKDFELISFHSVSKGMVGECGRRGGYFECTGIQKEVMDLFYKISSVSLCPPVPGQIMVDLMVNPPKSGDFSFESYTEELNAIYNSLASRAEKLAKAFNELEGITCNYAQGAMYLFPQIRPPPKAIEEAKKQGRKVDEMYCMELLNATGVFFGGDNSQQEEEENSEQKNQRNNKDYCQGYICPSNKKCVDAPIRCACEVRCEDQVEEEEKVKDLEFFHVFPKNQYNVISSGKKTELLLGLKNKGSGDQNIREVYGYFTPKDNFNKILRNLTRYQYPVKLEGGDELTIPYIFLPEVEPSEYGLVVIVEHFGQGEDKHRSVAFQDKVKVVGSDSYFDFESISIYIIGLLLAGFLFKNYFGSSNREQSKKQKKQQQKLKSEERENEIKKLNEGELDEDWIPQLRKSPRLKDKQKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Y7</accession>
    <name>A0AAD5U2Y7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002084</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000167">
        <property type="protein sequence ID" value="KAJ3222614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Y7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050994">
        <property type="entry name" value="At_inactive_RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010">
        <property type="entry name" value="OS05G0588300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010:SF5">
        <property type="entry name" value="PROTEIN TOO MANY MOUTHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042202135" description="SH3 domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="255"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="315" mass="34213" checksum="DE90FA1F154D156D" modified="2024-05-29" version="1">MKQHLITVIVLLAIILTQSSPADNDCQVLNEWAPTIFNNTDCCSVGTSVSGVVINCNPESRVISLSMLNGALPKGSKIPLNIGELKFLSWLDINTNGLVGELPDSFYNLTSLTSLNLENNNFQGIFPDLSTLKSLNDCALTGLGPVCLKEGISLPAICISFPLPQCKSNDTATTTITTGGKESKETSPNSGILIGSIIGGIALLSAMAIILIVVKKKKSNSQRNQKKNNELGNNGYFFESKNNKNNHDLLKDQIREEVNWVATEDYQRTLDDELDVNKGDHIEVQAFYTDGWVLGVNKRTGFQGNVALTLLTPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U332</accession>
    <name>A0AAD5U332_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endoplasmic reticulum vesicle transporter C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001943</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ERGIC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000160">
        <property type="protein sequence ID" value="KAJ3222775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U332"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="3">
        <location>
            <begin position="68"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="402" mass="45528" checksum="BEA1092C5293118A" modified="2024-05-29" version="1">MDVSGDHQNDIDHSIYKVICMISDIFKSVFQVRIDQNGRVVQKSKSTVGDVKNEVKKNETEVAACGDCYGGQLPPSGCCNTCEDVRKAYEAKHWSLTNMEEVVQCVREGMVTNMKEQENEGCNLHGHVEVNKVAGNFHFAPGKSFQQQNLHIHDLLQYVQHPKFDFTHNIHTMSFGKSIGFQNPLDGSGKVATQNYFMFQYFVKVVGTEFNFMNGTKAQTNQFSVTENERDVSPQVGSGGGIPGVFFNYEISPMLVVYKEYQKPFAHFLTDVCAIVGGIFTVASMLDGFIYNAEKSLKKKLDLGKGIKYQIFGKEMSISTISATLNKTILYSHPVEDVKNLKELQEKLVVLKNQLNEHFKPERESQEDEKEFENDDDDSDDDEENSNEILLKKRKLAKSEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U336</accession>
    <name>A0AAD5U336_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="24">WD repeat-containing protein 35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">WDR35</name>
        <name evidence="24" type="ORF">HK099_001937</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000160">
        <property type="protein sequence ID" value="KAJ3222769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000004">
        <property type="entry name" value="WD repeat-containing protein 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056158">
        <property type="entry name" value="Beta-prop_IFT121_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056159">
        <property type="entry name" value="Beta-prop_IFT121_TULP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039857">
        <property type="entry name" value="Ift122/121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057091">
        <property type="entry name" value="NDC80_loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057979">
        <property type="entry name" value="TPR_IFT121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056157">
        <property type="entry name" value="TPR_IFT80_172_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057361">
        <property type="entry name" value="TPR_WDR35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764:SF5">
        <property type="entry name" value="LD29485P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764">
        <property type="entry name" value="WD REPEAT DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23390">
        <property type="entry name" value="Beta-prop_WDR35_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24797">
        <property type="entry name" value="Beta-prop_WDR35_TULP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24487">
        <property type="entry name" value="NDC80_loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25768">
        <property type="entry name" value="TPR_IFT121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23387">
        <property type="entry name" value="TPR_IFT80_172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25170">
        <property type="entry name" value="TPR_WDR35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT121/TULP4 N-terminal" evidence="22">
        <location>
            <begin position="5"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="IFT121 second beta-propeller" evidence="20">
        <location>
            <begin position="368"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="IFT80/172/WDR35 TPR" evidence="19">
        <location>
            <begin position="740"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="domain" description="IFT121-like TPR repeats" evidence="23">
        <location>
            <begin position="1055"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="18">
        <location>
            <begin position="1215"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="domain" description="Kinetochore protein NDC80 loop region" evidence="21">
        <location>
            <begin position="1461"/>
            <end position="1691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="1391"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="1547"/>
            <end position="1656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF23387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF23390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF24487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF24797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF25768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAJ3222769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1707" mass="195772" checksum="5F8EFB3955D46DCB" modified="2024-05-29" version="1">MFVYLTWNNDQGWIACGGEDGLLKVLKLEQNTANQSTLPSIAASERRISNSQNVNNPTSPTLQNSQEQQSAPSNLTMNQTLEGHKGGVVVSTWNTQHRKLTTSDSMGLIIVWILYKGVWYEEMINNRNKSVVTDMHWNRDGQKICIVYEDGNFWFNKSNLLKICAGAVIVGSVDGNRLWGKDLKGQTLTNVQWSPDSKSILFGTATGELLLYDMNGNYLTKTLSYCHENAAVIKLSSIEWYNGINGYIEPKVPCLAICFENGKIQIMRDEKDMNPTIVDTNMRYLKMKWNNNGSVLAVSGVQIAKNAQGEEKELSIVRFYSPYGEFQRFLKVPGKRISSLSWEHNGLRIALAVDSFIYFANVRPDHKWTFFANDVLVYTYNRLERTETIVVFWNTKTGEKFAKYLNQVYFITSNNENCLIVTRSEENSEKYNFSIYNAIGTSVESKEIDFEPKSVSINKSHVFISSNEIVVDWQFKILGVNNTPQINAGAVNKFSALDALRRKETKERAFHIDDNTIIGNSSDSGQSVADVKQKQGTTDPIISTTASEKYLILIRSSGEICQYILPSLNLENKFNIYKKDNGQNLIKVFKSSLNSTSTRLLILDYSGILKMVNLESRLKGSSNAEDSQRLMDFEKKDVCDIRWAEDNEELFAVIEKTRMFVFRNYEPEDPIPCSGYTCHFSDLQIKVALMDEILSENENGLKESIITIETKRLRDAKNILSQSGLSEAVLYVEANPHPKLWKVIAEASLSSLDLNTAQKAFVRSSNYQGLQFVKKLRKIEDRLKQRAEVAAYFCNFDLAEKIYLEMDRKDLAIDLRCRLGDWFRVVQLIKSGGGISAADDMVLDKIRKNIGDYYYDRQRWVQAVTYYSQGKDMENLAECYYLLEDYVGLDKLAFSATDNHPLLKKIAKYFSSVGMCDQAVDCYLNAGDIKAAVDVCVHLNQWSRAIELAKLHKFKEIEALLANYANYLLDRNKVLNAIELYRKANYCQKSARLLFQLAKSTAKQNKSPLLVKKLYVLAAMEIEHYNHINKNTMKVGEGYPSIANKGNSDLIKKDENPWRGAEAYHFYILSQRQYYSGNLDGALKTVSVLILQRYVLILFTKKAFHLQEYEDTIDPKIIYSLLAFLSAQCKHFGTCSKAFIKLEALNSSNGENSEQEDFENLAFNIFTKESLLPVSKQSSNGSSRLSNRKSLVENFNNLSVNNSERNSLKKLISNERQSFIGRRSSNVRHSMVRQQQPFKDPRPIREKQWLVHAIKTLINFLVGAGYTNPVSQKTLQAPSAKDFQSIFKFLYAQLDPYFEYDKDKKFEEEVPMILKALRYPFAEQISKSHLYSVGSMHAWPSLLAVLTWMVELILCCENLDQVDSYEEDAQAEKIFYDYLTKTYTMFLINENNDYHEMVEELKGNFDKKNEQILKAVEKLENTNKNLEKQLTELTVSEQVVDSQEISPADVDRMNAERDQLQSTLIQLSNKQEEVNKRVWEKEIEIQKEMDKLDKLIKAFNDSSFQLGLSDPSADGDGKIYELILNFHASKTDEMLNLDLKNVVKPTLMALRSKNKESIHRIEDLNIQLQEEIEKLIEEISEKKEELKEMQQNIIKFNLQYTEQKDIMGNAISNSNKEKERLEGAIQKLKLEINSKLVQSHQKVKEMEIEQDQVQRKCHERSENNKKIIYKVLEDYIQYSSHVSECLTELDSIVLKEYVDAGGELPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U364</accession>
    <name>A0AAD5U364_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="3 11">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RGTB1</name>
        <name evidence="13" type="ORF">HK099_004841</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="3 11"/>
    <dbReference type="EMBL" id="JADGJW010000355">
        <property type="protein sequence ID" value="KAJ3219048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U364"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000012">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="12">
        <location>
            <begin position="3"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3219048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="311" mass="35257" checksum="36910116C0AE89BF" modified="2024-05-29" version="1">MTFLRNKHLEFIKNLENSTEKESFATEHLKTSAIYWAITTLDILDCLDLLDQSEVIKFILACQADNGGFGGNIDHDPHLLYTLSAIQILATYDKLDLIEPEKIINYVKNLQTEDGSFKGDEWGEIDIRFSYCSISILSILKSLDSINVKSAIQYIRRCQNFDGGFASVPDGESHGALCFCAVGSLVILNGLDYIDCDKLGWWLSERQLPIGGLNGRPEKLQDVCYSWWVLSCLRMIERDSWINKEQLISFILSSQDTEYGGIADRQGDIPDIFHTLFGVAALSMLGHNKNEFEEVDPRYCMTTRVTKRLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3C8</accession>
    <name>A0AAD5U3C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003604</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000238">
        <property type="protein sequence ID" value="KAJ3221300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3C8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF126">
        <property type="entry name" value="TYROSINASE-LIKE PROTEIN TYR-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041943887" description="Tyrosinase copper-binding domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="6">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="444"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="644"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="495"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="613"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="661"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="674" mass="77102" checksum="3853BCECC966B263" modified="2024-05-29" version="1">MKLNQLLALFTAIAPVFTAKQNCGSDYIRKEFRECTEHEIKNYIDGSTGHYIDDFTNAHHEAIGPHHSGTASFLPWHRLLLSTLEAAMRECTGNNEIFIPYWDNGLDSQSPEKSLIWNYFGKDGNINNDQIGRNEEDIKNYGECVDGPLKGVLFQHVPPDMINQSPDCLRRDFGARSTNAETFTLVTLEVIDLIIREKDFGTMCAGLEGLYHGKVHAWVGGHMGGLETATNDPIFYMHHANVDRLWSEWQLSNPDLARTYIGKNAEGEPVNEADLLELYNPETLNKYYDTRPVSDMYDTNDWCYKYTLSVIPAKQDGTPINSTSSGSPNNKDTPSSDNREDLFNQRTTKPYTAKAIKRLHLNMEQTGAWEELTNDYIRYINSLEGYVSYDALINHRNQKYISTPSNIYEDLKIVRGMLLDNFKQLNNLPESLKVLMDAENDLDELGKDDEENPEGGGAAGGEEDSADSEGSDKSKPPAEKPGTTESTDKSVVVDVGDKDETQKEKGGNKVDDKPKKKENEKKSDEVEEKKDQKKTKEESEKVDHTKAHKEHKENEDGKKGHKEYKEKEDDKKGHKEYKEKEDGKKGHKEYNEKKEKDVYGKANKNYGNNNSNEKGHSDKKYNEEKGYEKQIKWKETEWFEYEKPANYKDNGNLNSNSFDEQFYEDEEDSDFYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3F3</accession>
    <name>A0AAD5U3F3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001872</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000158">
        <property type="protein sequence ID" value="KAJ3222804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3F3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="508"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="508"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="622" mass="70488" checksum="D8BE0B5B19230CB9" modified="2024-05-29" version="1">MTETTTQRKTRSQTQEDKNPNPKLSPKKTITAVRKRGKKFELQEENELNNPILEPIAPRIKKKQKTYDSVEMIEDSVNTIIYQGSEGHTIMSILNNGQLSPRLRARLDQYLEKLTKTVCEAVGIDTTGAELKGEPDPNDRIAIETDEIYQSIKQQELDSSKYSTLTKFFELMELVQSAEELFTFAETDDNSKHREADIKTQELERALKILEGLALITDNLEDEGYFRATADLLTLICISKKFSLSEAEAMKEALKLFSSEITSATDHQKIAIVSRRQSEFAQNVKTLTTNFSFEDLSNNLVISVRSMLVDVLGFDDFDHNIHAPKAFFTHQTAQLNAEEELQLMEVTSNLLNTPSESLSHLRHTQQKGKGRAKQHEFDNSTDSQQSQNPFGRLPQAPQLFNAESIHQYQYYQHPFSDTNNQFLGYGMYQDPTMLQNATYLNQTPRNYGEGDSFTDSPTARTTARRQGRNGDVGVNGLDDSGDLSDIEEDQIVIPDYQTRQLEPPKKNSAGRGHGAWTPEQIRVLEKAIRKHGTHWAEIERNYRLQLGNRGQLSIKDKARNEIKRRTNNSLPLGFFHKALSSRHLSPFSAVNQGRAGSQTVNTASPLSNNMVSQEHEDEDDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3W9</accession>
    <name>A0AAD5U3W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001243</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000133">
        <property type="protein sequence ID" value="KAJ3223367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3W9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="322" mass="36467" checksum="FBA639E6391873DB" modified="2024-05-29" version="1">MGYDVNFFVAEGSQLCICYLCQGVVEEPFECSCSSSFCKRCLDVWLEITEHCPACKNHLSENELTKNFNAETNSFNLLVLCPVSKLNERQHQECQKVMTLENVFDHLTEEDLKLLKLPTVTYTQSQIFAIQNYFNGKNSYEVDDFTSAFEYFELSAIYNNVDSMLELAIMLKKGLGCEINVERSFHFFLKAADLGDSIGENKVAYCYLKGEGVIKDVKKAEQYFEKSAKKGQSDSQVQLALLFLEQNKEKDALQYFKLAAEQGNSTAENELGYCYLKGYGDANAVDSIAECFEFGYGVAKNLEKSLKLYKLALSKGKLKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Z5</accession>
    <name>A0AAD5U3Z5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000842</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Z5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05676">
        <property type="entry name" value="M20_dipept_like_CNDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF4">
        <property type="entry name" value="CARNOSINE DIPEPTIDASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="5">
        <location>
            <begin position="209"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="568" mass="63394" checksum="A80C9755602C01C3" modified="2024-05-29" version="1">MTQNTFSKVSEYIKQNEQRYIEKLRDAVAIPSVSGDINRRADVFKMGKWLVDEMQRLNITIKQHLPGKHMMDGVEAELPPIIMGSYGSDEKKKTVLVYGHYDVQPALLSDGWNTDPWTLVEKEGKLYGRGSTDDKAPVISWLWVIEAHQKLGLDMPVNVLMCFEGMEESGSEGLDDLIHSESTKFFKTADCVCISDNYWLGTTKPCLTYGLRGVSYFQISIKGPGKDLHSGLFGGAVHEPMTDLVLLLSKLVTPEGKILVPSIYDDVAPVTEAEEKMYETLDFSFKDVHNATESTNTIHKTEKELLMARWRYPSLSLHGIEGAFYSSGAKTVIPAKVIGKFSIRSVPNQDPARLTQIVTDYVNSEFKKLNSKNVIGIECLHEGKAWLADVNDWNFRSAATAIEKVFGVKPDMTREGGSIPVTLTFQEALQKSVLLLPMGRSDDGAHSTNEKHRPVHCVRNTKGADFPPNFPEVETTIEKGTLQHLEAYSGFKGEEKDLNSILKKLKIKRVFIVGFCTEYCVKATAVDSLSNGFETLVITDLICPVNKLNEEVVFTEMKGCGLKLIESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U486</accession>
    <name>A0AAD5U486_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">INO80 complex subunit B-like conserved region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000120">
        <property type="protein sequence ID" value="KAJ3223699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U486"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029523">
        <property type="entry name" value="INO80B/Ies2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006880">
        <property type="entry name" value="INO80B_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561:SF12">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04795">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01406">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit B-like conserved region" evidence="2">
        <location>
            <begin position="109"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="208" mass="24614" checksum="9AD2EDAE0DD9E060" modified="2024-05-29" version="1">MENDIDDEIEEDFEEQNEVSNEEDHNEIQEELDEQKEKGMEEDDVESELNLDDDLDDLSEDEFLKILQKRNEKKKLTKRQQMALTGENSNLSFLEPEVSNKKLKLTTEEEELKRSENNRRRKNLNQQRMERNKQLTIKKLLKKQAKKLNVKDNENLKNSAAKNTKNNTFLNINYVNKPDISLLSLPNSDLLGEKYLNYFEKNSLLRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4E9</accession>
    <name>A0AAD5U4E9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dynein heavy chain, cytoplasmic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dynein heavy chain, cytosolic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_002434</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000180">
        <property type="protein sequence ID" value="KAJ3222332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein 1 heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000122">
        <property type="entry name" value="Cytoplasmic dynein 1 heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000002">
        <property type="entry name" value="cytoplasmic dynein 1 heavy chain 1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000005">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000003">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000071">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000517">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000003">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000004">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000004">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000373">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="1942"/>
            <end position="2075"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="2240"/>
            <end position="2377"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="2610"/>
            <end position="2760"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="2954"/>
            <end position="3115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="3244"/>
            <end position="3278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="3434"/>
            <end position="3461"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3222332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="4666" mass="533410" checksum="FE1723826957A2F9" modified="2024-05-29" version="1" fragment="single">[encoded data, 4666 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4G9</accession>
    <name>A0AAD5U4G9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000178">
        <property type="protein sequence ID" value="KAJ3222377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4G9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12824">
        <property type="entry name" value="MRP-L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="299"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="343" mass="39985" checksum="D0C1DAD42C56206D" modified="2024-05-29" version="1">MPDGSVLILRENPKPEAIKYNSIMTEDNLPPRIRPLNGKKCDFTENELTEARKLRQKDPGTWTIVKLSDKFNVELDMVRLRCPAPKEYSRAIRKLNDEIFENRDLAAKKRIIERIRRKATCKQQQPLQPAEHHLDIQPQQKSTSPKSVLISLKDNKFVMFKSREPVNKIKPHTVFKSPLTDNAKKEHSAFCLKSILKVHHTNVSSKVLEVDIKEDKMLRKKRKNSTSLDKENVKLMKDCNQPEKTILLNIEEEIQPKEFVVEDNRSIDSNENSKLKDSIEENFQTQKPLKEKDIVNHSCVVCLKDINVIKRCSRCKNDDFYCGVSCQQTHWNHHKKNCLKLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4H0</accession>
    <name>A0AAD5U4H0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000363">
        <property type="protein sequence ID" value="KAJ3218827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4H0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="813" mass="88890" checksum="7377B9CA4E1DD355" modified="2024-05-29" version="1">MTLFIVVLGNTSLNPREVKKAQEKICPVPVTITKSVFLTTIVEYRTKITTVTNPTVTKTVTKYRTKTITNTKFPPPQSQNNSSSYTDSPSTSTNHATVDDIYTTEFNEVTKVSTFENQRVTTSIKYFSNSPKSNAVSTELYGVPEETTESSAHVTVSDRYQTSPSTQIDNANVVTDNYSSTSAGEITHLATLIPSSGFTKGPHQSGQVEVETFSVRQTVYSSSEYYESTTLAAVAVDSVITGVHSISSPSQSEELNTAAQTVAFTEGTSEVYFPGELTSGPESTTLYTPSVEYSTNEYNNYVKDSTTQPHIFSTTTVDNAHSSVEFNTSPLQTGVVETFHESSLPTTEIINAEETELFNSEIFKTSSVQPSDSIHVTAAHSTSKRPSHSQSINTNLEVDEVSTAVFVAEETEIIEFSTAQAELTSTQQGVVQVTEIVSTNSRILPDSTTAVVHTQWPVWETDVNADSSTKVIGVLTSGAEATNVPKTPTTTYTKEFSSTLYNQWPHWESLSSEPSFSTEVDSLQTTKSNNVVNTNDVKSTKTKDFTTVDNHQISETVVLENQSSNEVSSNTAISKSTSKDFNAIYTLEEQKTTNTQNFVFTSASESVSFTSTSPSTKHHSSAAQTPTDSHENPTFTEKFPLETPKETTEYLQEFETSTAFENAAEESSESINVEDFETTTQQSLATETSVAPNPTLTSVALTTVITLTSVQPETTETIPVVTTSTDEFGEIVITSFITRVIPAMTMTQTVIETFPTFILTNVTPVVTVPKYTVTETFTYTLGERTYTQTFVRTLTPTDVATPAPLVRKFYLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U584</accession>
    <name>A0AAD5U584_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GUK1</name>
        <name evidence="10" type="ORF">HK099_007867</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000080">
        <property type="protein sequence ID" value="KAJ3224823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U584"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:GMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.10:FF:000002">
        <property type="entry name" value="Guanylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000776">
        <property type="entry name" value="Guanylate kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.10">
        <property type="entry name" value="Guanylate Kinase phosphate binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117:SF13">
        <property type="entry name" value="GUANYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117">
        <property type="entry name" value="GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="9">
        <location>
            <begin position="3"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3224823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="21136" checksum="0455DEE827CF1E07" modified="2024-05-29" version="1">MSVVLIVLCGPSGSGKSTLLKKLFADFPEKFGFSVSHTTRNPRVGEVNGKDYHFITQKEFEREISLNSFVEHAEFSGNCYGTSLRAIQDVLDSKKNVILDIDMQGVLSLKKRIWALKPLYIFISPPSLEILALRLKSRGTENDDSLQKRLQAAKVELEWGTKPNAVDHIIINDDIEKAYNELKATLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U592</accession>
    <name>A0AAD5U592_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_001159</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000130">
        <property type="protein sequence ID" value="KAJ3223435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U592"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16658">
        <property type="entry name" value="RING-Ubox_UBE4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="12">
        <location>
            <begin position="1014"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="63"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1095" mass="125933" checksum="2B1FCA39691C51D5" modified="2024-05-29" version="1">MSSANQDTIDMNEDEIRKKRLAKLASHSASQNNNPKPVSAIVSSLPSQKSAEVKVSNFQKPAEAKAINSPKKATVEISSPTVTRKSVTSGTPTTPSSAEAKFRSQSHEEWEHDALCYIFHVSLEETQKPYDYLTNLAETLRNEQKPLLITSDVIESIIFERLSLENPKKKLPIFDYLVECWKRCVFVKSKLVNNYQEKSKDDASLRMLVEYRKNLLCNPKGYFNFIVSYSGLVLNDMLEMFPQAEEVVAQGARYLGSKLLMQDVSIVEEQVPKAFLDEFVARFNGDGLEDVPRVQNFNPANTTPKTLEVIPFFGPFFRQISIFAELDPQIGENYFFSNDSTLSDGVELNGFNIGNRNIADVKSSMSVLQNLSFRSQKMLYEVVMLIIKSSPEAKEAILQFLADSINKNRSRGKLQVDKNTVSSDGFMFSVVSLLMFLVEPILDQNFSKLTLIDTKYLHLNSRLIIELDDTRILSEQAQTEQFLKTLKEINDPTSINKPNFISDIFFLTIFAQHYGFLAILRFYQNFVKQIEEFRGQVAVMREKKNSGGFQGPQEAMATMALAKYEKQLDQMISLKLSYDSLITDHQFLKTNLKFYDLVIAFLMRTVFVGCELLTQGPKVDQGFNWFNFFRGDLRSCTSLKTLDLSKLENIKQPDLFFNLPEFIFEDIVEFYLYILRFEKPLFKNTDRNEILTFAMFFLTNSSLVKNPYLKSKLIEILFYFTLPLYKTRTGETIGRLDEVFSTHPFCKEYLVNSVLKFYCDVEQTGMSSQFYDKFNIRYNISQILRAIWPDFLHRQKVIDLSQQDFPFFVKFANLLINDTTYLMDEGLSKLTEIRNVQNEMASPDWESKTQEHKNERLGTLKSAERQAASFVSLGNETVNMLRYLTTEEGIVGPFCDKIIVDKLAAMMNYNLVALVGPKCTELKVSNPEKYRFNPKKSLKNLIQTFMNLSNKAEFVEACALDGRSYNKSLFERAIVILEKNFLIETQDIEKLMVFLNKVETYKSKVEEEEELFGEIPDEFLDQIMSTLMQDPVVLPSGNVLDRSTITKQLLNNPIDPFNRQPMTVDDLVPDLELKARIDEWKRGMKGKRGEPMQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5D5</accession>
    <name>A0AAD5U5D5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000075">
        <property type="protein sequence ID" value="KAJ3224964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5D5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="295"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="591" mass="68423" checksum="FA26D6F9390FFB10" modified="2024-05-29" version="1">MSAKKSRFDLLDNVEKNISDYEIELDNILFSKTTHFAKEKNITNECNKEKQEKPKNEIGEKSPEKEENDAAKTEESFRLKKKAVEKLGKVDPRLTSQRSIFFSKNNLSSRKSSIVFNNFSNSRRASSIFSSSSNFFSGDSFSSEVLKAKLSSFNNDLVNKIENSAVSDEAKLKVQEEIPFPITQKKEKKELNIMLNKDVFGAYNYKVKDNDFRYFPNLIQKLNLNKRNNVINNKNKFNIEEENVSELDQIVEITFFPNPSIKYSNLEKDIKMEGKRIESECEKLHDTIFSKNFEIKKTLNECEFIREEIKNLQRYNELLEAKINNFVLENVNLCQTKIQRDLQKERAPSPQKNLLPGYSNSVILSQSNINSTFSLNKTKNQFILEKILSLAQNFSKELFSLAMFEMQKIEKEFAKDSELVATFEKNKKKKFRNRFSLQQSHLTDGSRSTINFYSKDILSSKSSLGNHTRENSLSFHSNSINLSQRSLSNSPTSPCQSIPNSAYHLSATSPIALNNYSVSNSSYHNSTYSNYSQNFNNSPYLPDYPNGEFVGRNENYYESEEQLELRKKNENWVKANKKIVPLIRFFHATEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5S0</accession>
    <name>A0AAD5U5S0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000064">
        <property type="protein sequence ID" value="KAJ3225331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5S0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="304" mass="34221" checksum="0F25B2CF3CFF97CB" modified="2024-05-29" version="1">MSSNLRFVFTVINHYSGVVGMACFLYVLLDRFKLIKVVTPYSVWWDIFLLVLSTTAVLILFGANTTSIICGYLKSSNTQPPLCKSFASSKISTYIAAGCQAYIQMIDFFLGTILLIKVLNIEKIQNSIRDQRKKLNLNLKKKIIVSSIGWLITMILAFSCYIISGFCYGCVTTIELGTVCKQCFATPDYDTFRKIIYIISSSAYLFYVIELGFFSLTVTLISELVKLGRGTLTEAEPGLIKSYFRQIIKKVLERKHGAIADSSKANTSVHQPTILLQVTDFKSTENDEFKDFLESKDDFLSSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5W6</accession>
    <name>A0AAD5U5W6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ubiquitin-protein transferase activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CDC20</name>
        <name evidence="10" type="ORF">HK099_006585</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5W6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF8">
        <property type="entry name" value="FI02843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="9">
        <location>
            <begin position="239"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="367"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="497"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="537"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3225551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="560" mass="62108" checksum="A207866865E472DC" modified="2024-05-29" version="1">MKNIRSPCSPISSPRFSQRTNLEFSRASAKKKSQSLFNGSPKSYLSNNSNNAQMSPLKTLSKLSKASIALASFRKQKVNETCIFSFNPDEHKQSTLLTTPKKNSQKLELEDDSFWLGAGNVSQTPAKKQPKTQKAITHDRFIPRTTSDTSATFAVEKSASYIEAKQKQPSYLDVNAIAYQEEVAKACGVALDKRILAFNIEPPPSDHRDVLKANWNRPLRPPNSNLAKRKISTQPFRVLDAPGLLDDYYLNLLDWSPSNLLAIGLGRSCYIWNAVTGTADELFEAEEGDYICSVKFSSCGEFLSVGTNFNVVQIWCSRTLKRIRLLKGHVARVSALSWKGATVTSGARDGSIWNHDVRIAKHKIGELASHTGEICGLEWRLDGQLLASGGNDNMVNIWDARSSLPKHTKTDHTSAVKALAWCPWQLSLLATGGGREDQKINFWNTTNGSKLNTINAGSQVTTLIWSRQYKELFSSHGHPNNRLMIWGYPSLTLISEMNGHDDRVLHSALSPDGQTIVTGAADENLKFWKSFESKKKKQLNSGAGQNEPDLSSSFSKMAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Z6</accession>
    <name>A0AAD5U5Z6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable RNA polymerase II nuclear localization protein SLC7A6OS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000189</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Directs RNA polymerase II nuclear import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IWR1/SLC7A6OS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000103">
        <property type="protein sequence ID" value="KAJ3224139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Z6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040218">
        <property type="entry name" value="SLC7A6OS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013883">
        <property type="entry name" value="TF_Iwr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31196">
        <property type="entry name" value="RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31196:SF2">
        <property type="entry name" value="RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08574">
        <property type="entry name" value="Iwr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Transcription factor Iwr1" evidence="11">
        <location>
            <begin position="216"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="247"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="298" mass="35561" checksum="1DFB855D8C44CB7E" modified="2024-05-29" version="1">MISTINNDSNKNSTKQVYLKVKRKRNEGPVNVLVVDRETSKRAKLNNKNNVQIKKVQEQKVFRLVETFDDELEETKPYNERIKDVHERLILLHRNKVSIKKEEKKLKSFNEKRMDLYNEKVKLSKASRYKVVLKNRKTFDLKEYKDDNMEEDIIQVVDVVKEEEDGEDANWNYGIPKVLNSKDIKKHSEDDILCNYEPMLREFLNVSIDSNKKKKEEFVYDIYYNENLMEDDETDEKNNPEVEIAGLTWNEGNQGNFIESESEDEYQEEDEDSNEEDYYKNDYPEEEDYDDEISGDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U618</accession>
    <name>A0AAD5U618_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000099">
        <property type="protein sequence ID" value="KAJ3224242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U618"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="141" mass="16691" checksum="DD3BDB0FBE45B075" modified="2024-05-29" version="1">MEMTEFRKNPAKSEDLDLKELKILVDNMFQEILQSYIVHERHCTKEILLINEECKILKNQTERYKAELQNKKKTIINDESKVDSSEVKNADVNQLKEFMLNSQEAMEMERTKLLLRCNIAETEVTELHNYINLLKSRGDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U669</accession>
    <name>A0AAD5U669_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_008462</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U669"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07843">
        <property type="entry name" value="STKc_CDC2L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000054">
        <property type="entry name" value="Cyclin-dependent kinase 11B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000211">
        <property type="entry name" value="Cyclin-dependent kinase G-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045267">
        <property type="entry name" value="CDK11/PITSLRE_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="80"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="374"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="429" mass="48847" checksum="22FCCD388E8E2084" modified="2024-05-29" version="1">MNVIKKSKWDQSDEEVEASAKPEPLKQKKKKLKTSKKKDDCSSTPNFDPGPPPIPCKDMKKKSFRMFNSSNLLNGPVDNYENLNRIDEGSYGIVYRARNRETGEIVALKKLKLEKEKNGFPITSLREIYTLMLAKHPNLVDVKEILVKPEGTGIFIAMEFVEHDLKSLMESMLTPFLQSEVKTLMLQLLSAVNCMHQNWIVHRDLKTSNLLMNNRGQIKVADFGLARRFGDPLGDMTQLVVTLWYRSPELLLGEVVYDTKVDMWSIGCIFAELVNKEPLLPGNGEIDQLNKIFKLLGTPNETIWPGFNNLPGAKTFGFTKYPSTLRSRFTYMTENGMDLLSKLLCYNPEERISAEVALKHPYFLEHPAPKDSNLFPTFPSKGANEKRKSYASPSAPHGNHGLDRDEEEKELRNALNAHKFESTSFKLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6B4</accession>
    <name>A0AAD5U6B4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPG/RAD2 endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000050">
        <property type="protein sequence ID" value="KAJ3225872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6B4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09858">
        <property type="entry name" value="PIN_MKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022039">
        <property type="entry name" value="MKT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022040">
        <property type="entry name" value="MKT1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF32">
        <property type="entry name" value="POST-TRANSCRIPTIONAL REGULATOR MKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12246">
        <property type="entry name" value="MKT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12247">
        <property type="entry name" value="MKT1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Post-transcriptional regulator MKT1 N-terminal" evidence="4">
        <location>
            <begin position="325"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Post-transcriptional regulator MKT1 C-terminal" evidence="3">
        <location>
            <begin position="530"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="826" mass="95575" checksum="1461B36258A72C53" modified="2024-05-29" version="1">MTIRKFDNYLNERNLQSTLPLSALNEVRLGIDGLLWLRKILKFKSNDSSTDLNDLGKIFASIVATGGTVPFNTLNEVITKELDNFKSVELMVNIQPFFVFNGLQVRHVRDQSHKSFLLTDYRESTRESAWLSYEKGDFKSAFELWFKSNSVGVVDYLSVVFKILHDNNVEFMRAPFSQWAQLVYLENHPKQLTHCTYSDTNILVWDGIERCITHIDFEKNTFKFIEKSRVLADLNVSNEQFLDISIMAGFDFIDTFPPIATAFDFRKAVEAGANYLATLHNFLEHPQVMELNYVEMFNRTKTTIRNHLILTEEGRVEPFARDYAPNDLHEIFGFRYPDELFFFLCHGVISPQLMIYLHTGAVFESHPLGKGDSLEYRNFLKSSKLLELRGIAFNLLTWNLHVNIQNQPMVSVNWFEKELNLGIPKPEITGLKWLPSVDHTQLPQPPHVKTPQLSDKNQILPSKTVNWFPDSKKKQKTEIIDIKFVLKTVQLFQRFKTTQPKDPNTLNPSLLREFKFCSTTEELQSLLLLRLLEVLNYSHNSIHLRTFGIALLKGLSLQPVTFNSSATNVTESANFSANNGEELLNVFELLKKGVLNNSKFQKNYEYTESFVKIFANQPAFMQDEKKTYCHLRLIIRVISVLNFQLKAGKLFPGQFDRSLLEFNNFVKVSNRCTRNIFESILISYAVNDQQEILKEYNSQQQQPEENKAFINSTKNILKFNFNSAIINTETNSFAKQMDHTHYNKSLENKKLGEKGTDLIELSLAKLEDIYQDASSFDVRDQFYRGIHFWKQVLEGVKSLANAAIDGIPKDLTQAFLQAEEWFKDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6B5</accession>
    <name>A0AAD5U6B5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000149">
        <property type="protein sequence ID" value="KAJ3222982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6B5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="254"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="476"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="571"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="642"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="706"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="765"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="836" mass="97813" checksum="825108D7E8504AE1" modified="2024-05-29" version="1">MNYNLLKNTDEKGGVGNSTKFVSLEKIDDLHQDDVEKFDNQIQNMNNVKKFVSFNEKNFTMVAPPRTTSSLLLQNNIGRTSISTQLSNNENEKVKLQAVEIDRLKSLIKLQSEKENSYIYAIEVLHDEIKRKDTTINNLKKVNLENNNNFLGTDDKFPYNIDNGKEDIQSELLWNQADVMNHLKSLLFTQSTKIKNTAKKSDLACLNAEEKDNLISKLQKNLNLMYFESEKLVSKINEMKLSQDLKTQELLNLIHEKDEMLKENEEMLNSLELNLELTVNESRQVEAEYKLKSELCEADYSDKLYFNSVQLEEKNAIIDDLNNSLESKETALKNLQFKIDDLQRNENNASKFLNEIEMIESGINEHKVKFIQELQEKDLALKYKEEKILELEESIRTVNDEKTRIKTSFELKLNEIKNFEEKIYKGYNDELSERELRLREKEDIIHAMKFELEDLQILFKATKEETVKLPEEKAVASNLQKIINETQEELKKLQLNYDIKKRELGEEVTKKEELALQVLKKEDDIKSLKKNLNIAVKDIEKSFDENIKLEKNFKLQQNEFDALRIKLESSCTVKTNELKAAQEKIEKLEKSLTAKSKELLLLEEHIETKDTESHKNIDDMTKAIKSSLQRKCEENTKLLTSLSICNEEKATLEEKLRKQKLQFHKEVVEKEEEHLKKSNDLNFALKTLKLALESEKQENHSNIEEYEVLSKATKSLKMEIEDLKVELNKKNTKISNFQLEKLKIEAMSLELGEKTLNLIKEKNILQEEINVFRSLEEKNKNIIEEWSKEIKKLRYEKESIKIKLENYTKANTDFSEINSDVLIKKGSIKLNEKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6B6</accession>
    <name>A0AAD5U6B6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Centromere/kinetochore protein zw10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ZW10</name>
        <name evidence="2" type="ORF">HK099_008200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6B6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048343">
        <property type="entry name" value="ZW10_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20666">
        <property type="entry name" value="ZW10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centromere/kinetochore protein zw10 C-terminal" evidence="1">
        <location>
            <begin position="427"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="742" mass="86620" checksum="6B05AFA3ED75CC77" modified="2024-05-29" version="1">MLQNSEIEGSRPPAEISTVIESVKNELLSTIDSHNNKTIHSQTLNFHIREDLARISEFIQEKLSQASTVELEILKKEETILNLLARMITQLAGFDEQLDAGDVREAAETLLQFECGLDKLHVLQMENENMCPSTIEDVLFDQYLDRKTTLKLLEVFSVAVLFESDLGRSSESLHIQTRIISTYKGKKATTRKSFLTPVSLDTIFSSLELIGLLKPVITEFSMQLKKRFLSPIFSDDFSFKKELVIEKVQNTFSLMYEKDINVSGKKKNSNDTKKNDVYGFFDKLKTLGNFLNMHLFSTTNSYGTLRASEYFSEICYEILISEINKVFYNNLPSDSLKLEDYIVESKLNFLQFENEWKELKLLPPYKNEIEKILINAKFTYCIKRRNELMNITREVIMSQDWNTVEVQDATERAKDNLESNAYMSEMKFPHCLISSHAQTVMDMVYQTIQDARGIKGEDSVMEMFYLAKDMIGINIYNHEVYFLKDLYRALFPIVHSENLQNFPARTMIFWNDTQYFCHHLLTLNEFVKRNCSISEESKFFFNTFGTGLDVIDDFRRLGEHWFRQIMRTIRGEILFHNNKCGSFFALSTDKNLEVAETAMRGSIFYLTTLSKNLMPILPRKTYLETFGILVDTLLLEILRKVLLLKNEEAQINEEKLLKKQDFFQLNYVLSMAEKLKTVFECSNSHKKFKKLTEPDEKVPIQKFSKWWEFYFQVLTILNRISFKNDFQNSDFLPVLDLIKATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Q1</accession>
    <name>A0AAD5U6Q1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000148">
        <property type="protein sequence ID" value="KAJ3223007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Q1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="634" mass="72651" checksum="FF9D11DAD7795376" modified="2024-05-29" version="1">MQKRISLNKKFSSKDALTLEKARSPAASNKSNTPSCATAPSKITQFKLSVKPTTGTRSRANSIKTSQFDVFELQERLLHRRNTVKKITSAVGTPGKNFNEVYSEDFANDKSIKLNLKIPNLFENQQKRLKNLERNIRSVCANLNPETKINFRHYDVLEERRKRLKEFEEIPSSASDYNTAIDKSENQQHRTSTSHKAFTNWKRASLYGKVIFAMKPVRDTNNEVIASEFEAKTALAENVETFDDIHKKKAVKVAAIIKLQKSVPVVKKNGRKILDKKLFSTEINGGIVESNENLIKEKVGKTENFSCIPMDTQLKAMQMMECKNILKVFESKGLEDKITEKALVKSLVFPEEVLHKGPQKLKKKKERGPNQNYINSLSLSRKETLLKKLLKNNSVYSDNDSSDETGSNYSDSECSSQIYSEKKTKVSSAKLRKIQKRIQERNAKDWFNFPNIVARPVNFEELLEEQINNTSDKNRCKVKSYWKKNEFLKIKRNFELKKMTDLKSKEEKKLKLNTLKKLKLESRNVKNTLNGSRRFLSSKKAKTTENNLILVEKSSEIDESANNTWFPSFDHPGNLHPTSESLFGKTSNATSRVGSSFVRKVGEDFSGFLPQIKPQDLSTMHIQEFYTKYKPNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6W7</accession>
    <name>A0AAD5U6W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000034">
        <property type="protein sequence ID" value="KAJ3226525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6W7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="844" mass="93868" checksum="CD87993D6F33D6A1" modified="2024-05-29" version="1">MLLGSHKEEFDRFYKACQEWEANSNWNWLQTIRSKGELSTLVRNLINVNNDATGQKSLKLSDDLIFRWINYASSNFTAFAKWIQDHTDEKIASNAEQQQNEVVNLYNINNNGITKSCNNTGNNSNLQQLSALYNITNNTNAANFNVGNVNISLTSQNQIQSNQFHHQEQKVLHQNTNDAIRSSKLWQTSSIIPNTGGKKSKGPAVAAEPGSNKNYRQQLHHCVIPLSSATTKQKKPSKKVQAALLAAQVSQAVLQASNNSSAVTLQSNSSQCQKNNSTPTNTPILQQTSNTLATPTVSSHTPSPLSNINVASHTNGNGFAPRFNLFQQQQLSNQQGTGVFCISSNNATLEPKNLLQQNNNSQLPSYLNQNQQHFSPNCNVGQLRVNQQFQQNSNSNKIQLSLLSQQQHIAVLQNSLNFCNQQQMMQQNIANVGRRLPQRHSANMVPQSLKQQLSNHSNILQTQLINLQANCSGSSLPQQKVHFPSTPHQILSQVPTNSFLQDYQGGTDQLLFNHQQNLFETQAQSSQLASNIDIENREVDCSSSASIVNTPTLNKANASTSKPQSNNDTKLSSSEDALDTITPTNLEKNTSQSKDSDVPCVSSFVNAPTFSSNKTIVSPTTNFFYSNAPIAENSVITNVTAFSDNGIQPSNVLVSHTNHISIPQQLMQQINSQEYLSQLPYSHPNISSDIPVTTMAGSNPFKATNGVCLATVQPPSQPFLGSNFVSNKVTTAFTTPLIQKTLPSNNYHLQEQFIPPQNQIKSMFLQQHQQKTQQVEFMKIHDHKIRMENDVYFNKMFKLVKSKDELFSRPFYANEGVIDNIVDEVVVGLNPFYDFLTRFEDNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Z9</accession>
    <name>A0AAD5U6Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_000931</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Z9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000177">
        <property type="entry name" value="Apple"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF47">
        <property type="entry name" value="APPLE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00223">
        <property type="entry name" value="APPLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Apple" evidence="14">
        <location>
            <begin position="208"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3223581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="279" mass="31795" checksum="42F257ED8C33ED8E" modified="2024-05-29" version="1" fragment="single">LFIGESPNITIGNIEVEDVCTNLYENISEKPTGWKESVELLQKEIKEDKIPTPGEKTEGWKMDAHKNLPGFVQLYNKIPEADWYIMLDDDTYMFFGNLDVLLKKYNPNHDHYFGTGTLFNGCDGVTKFGEGPEFAHGGSGIVISRSAMKKMVKNSKKCIKQYRDCWAGDVRTSLCLRDQGILLKSLPGFNNFTPDKFTFNIYDKKNEYELDLNRKGNDFKNLYCSTANLCQKICTEHQSCVAWTFEDQRCWLKDGIPEGEFSIGSISGVLFKKYSCEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U707</accession>
    <name>A0AAD5U707_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000140">
        <property type="protein sequence ID" value="KAJ3223192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U707"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="30160" checksum="08B0B6F8D25BDA78" modified="2024-05-29" version="1">MSVVTALPSNYNTVFLNGNCKYGTLCRLPHVKENTTTAKIANNNNTSTKVVNSKSIYVKNRCKSDVIASSTVTNDISYATILKPKPEENLESDSSQEKITLQFSNLELQSNNDLNNFTVEEESIHSKHFNYLEENIINFHFQQQTHFVDCELNKNYNDNIYFNENSEKFNNMSDLNNATFLNDSMNFSDLHTINNMPSFNTIQNITEENICENQSIQNNNENQKNNSLLNGLPNLKSGEFINYPQKSRWNPWNNNFNPLASLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Q1</accession>
    <name>A0AAD5U7Q1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Q1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010737">
        <property type="term" value="P:protein kinase A signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="270"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="795" mass="91912" checksum="BB9D2DE54CECBBBD" modified="2024-05-29" version="1">MDNKTTTATATKRDTSSNQAVESIIENLESFSFAEQKQSVSASEEKPLKIKTQNFTTFNATTPSNLLISSHLITPTSPKLTSVQSFSPTVLTSTKNSISFFIPFNKKILKYQVLSENFQFQKLKNVKENYTSEEKKMSLHFKQHRAALRKSFILQSKLHKLRIRSERIKHNLHLKNQRDRLIILKFRTKNDFKISSANLKKKIYLKLKSEKFGAVVERAQTVALVNKMRKYIDAKKSFIEQVSKDLHQADEEYYGEEVVGDFYNSSEPPVFPIPSPTSSSSESHNTVLSANSDDHNDNDDSTKSLGQMAMEMHFLPVDMFENLTEKIFLKEYGELLPMITRFTLRELDVDEIIDNPQLRHDLYFDPNLQFKPNFQGEKETRKKIEQNMYWDRLEVEFKNNDLYRIPLILFEIKQILLNLLPITEELSAELNSHFDLRLLEQQIKYKCFQPINLIKYLTGMLKENCAPVRDAAVDLILLEAEKGKFCSAIREIFNVLEMMKLDYANHQLTRLRQFVIENAAEYEYKYFKTLNYDPELPKTTSWLRNSYNSIITNNSPFVKNIPNFVLNFKTVFFNGILDLILRASEFDTMDTPETLQMDLNRMIGFYNDWQDITIMSSLLVIFKQTCGGKTVLTNEVIKKLKTSLWVLLNDNETSLKHVSLQIAQVSGKIRRKALDKEEVEMLNRVVEKTLSGVDGPIFKLMQNRIGNIIFSCTMKQSNFTNTTSLKSGNEATSSAPNKILFFEQGLALKLGLLEFQDEILDLGERIKSVSDLNVAVFFECHTKIWNVLVSGQREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U925</accession>
    <name>A0AAD5U925_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000094">
        <property type="protein sequence ID" value="KAJ3224391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U925"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="471" mass="54372" checksum="AB313D7716901303" modified="2024-05-29" version="1">MYSNNKQHTSSSDSDNLVDINTSNLNANLIQKANPEFTTKNWIYQNPDTGQHLEKNETSIKDRFLVKNFYGSNYFTFDYSFLNNFTKTESSLQVKSFYQKFYIRNINKLNNKRLSCFDFSVNILSDASKHFSHDEFAVVTLTFTNLNKDDKNYLHFHLDSNLASDSEEKLSLLNKNIINISKNVVSFKEKEDVKVTKLNLVYQFSLEDRNLILNLTDDMEVLLGLTFFSTFNNTSFNETAANDIAKQEPTAKKRYESLHFFGLNELKLKFNFEEIFTAVNSNTTDSNVYNSRTAGSTETSFLHDIRFVFGISFGLFVLLATFFGILFCYLKRERKNANNLEKNDVGLDSSNGSSNIFNVVIPDIEESENKKLSSSEDLNSTERIQPIYNLIKFDKIQEEQITKNEWLSPEDRRSNNVTNSSSDISYNNKELKVNNTSSKKFKEYICKKNYKTKKADEINLNLGDILIIDQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA94</accession>
    <name>A0AAD5UA94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3</fullName>
            <ecNumber evidence="6">2.4.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">STT3</name>
        <name evidence="24" type="ORF">HK099_003638</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3227015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA94"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004579">
        <property type="term" value="F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043687">
        <property type="term" value="P:post-translational protein modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12610:FF:000001">
        <property type="entry name" value="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048999">
        <property type="entry name" value="STT3-PglB_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048307">
        <property type="entry name" value="STT3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21436">
        <property type="entry name" value="STT3-PglB_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="181"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="22">
        <location>
            <begin position="36"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="STT3/PglB/AglB core" evidence="23">
        <location>
            <begin position="528"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="423"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00059243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00067960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF21436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAJ3227015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="690" mass="77918" checksum="21E533D21A6B6281" modified="2024-05-29" version="1">MQKQTTKISSASVDSYKTGLRLLILMLIGILGFSSRLFSIVRFESVIHEFDPWFDELSWYPLGRVVGGTVYPGIMVTAGLIHYILHLFNFPIDIREVCVFLAPLFSAFTAFATYLLTKELKDERAGLLAALFIAIAPGYISRSVAGSYDNEGIAIFLLMITYFYWIKALKTGSSLYGSITAFFYFYMVSAWGGYVFIINLIPLHAFALILMGRYSPRLYVSYTSFYIIGTLSSMQIPFVGFQPTFTSEHMAALGVFGLLQLVAFSYLVRSHFTEKQFKSVFRVLLYGVGAAGAGLLGLLAVTGKIAPFTGRFYSLYDTGYAKIHIPIIASVSEHQPTAWPSFFFDLHVLIPLLPAGVFLCFKRLKDEHVFVILYAVSASYFAGVMVRLMLTLTPIVCVASAMAFSELFDTYLEPVPVAEVTTTVNDSTPSSFSKSSSPKKKSDSIITSKHQLSNKGIWGVDIKYITIIPMVFILWHFVLHCTWVTSNAYSSPSIVLASRNPDGSQHIIDDFREAYYWLRENTEEKCRIMSWWDYGYQITGMANRTVLVDNNTWNNTHIATVGKMMASSEEVAYPIMRRHDVDYVLVIFGGVLGYSGDDINKFLWMIRIGEGVYPKEVNERAFFTDRGEYKVDENATPTMKNSLMYKMSYYRFPELFGQQQAVDRVRGAVIPKKPIKLSTLDEGNWNKQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAC2</accession>
    <name>A0AAD5UAC2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_002662</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAC2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd09630">
        <property type="entry name" value="CDH_like_cytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015920">
        <property type="entry name" value="Cellobiose_DH-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF3">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042098154" description="DOMON domain-containing protein" evidence="8">
        <location>
            <begin position="24"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="9">
        <location>
            <begin position="27"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="10">
        <location>
            <begin position="158"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="35839" checksum="E3B07EB7ABDCF6D3" modified="2024-05-29" version="1">MLPSFLNVPLLIIISLNLVSTQAFCSKDLTDQFCVYSQDKSDSVEFRMVGPPNIGWMAIGFGSGMSNAEIYVGYLEGNTPKISHRSSTGYDLPPILPTADSTLVSAESGIKNGILIITFLVPKSRPPVNGQALVLNATPAKMIYASGTDKVVNNNFNYHDRSHAAVTAKLLDAASSYSSGKGPSETSAEVSTKEFYTNIHGLIMYVAWFAFAPLGIFIARFGKGRFKKWWYKLHLFCMLLGTFLLSIIGIVFIWLGKDASNSPHFALSTYSAIPVGAAHLIFGLFVVIISLLQSVLGFVIDKLFNPERTSIPWWDKVRTVKRKCTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAG4</accession>
    <name>A0AAD5UAG4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">DNA replication complex GINS protein PSF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GINS2</name>
        <name evidence="10" type="ORF">HK099_001908</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GINS2/PSF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAG4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11712">
        <property type="entry name" value="GINS_A_psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21694">
        <property type="entry name" value="GINS_B_Psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1020:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.5.50:FF:000001">
        <property type="entry name" value="DNA replication complex GINS protein PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007257">
        <property type="entry name" value="GINS_Psf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056784">
        <property type="entry name" value="PSF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25005">
        <property type="entry name" value="PSF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028998">
        <property type="entry name" value="GINS_Psf2_subgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160059">
        <property type="entry name" value="PriA/YqbF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication complex GINS protein PSF2 N-terminal" evidence="9">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="GINS subunit" evidence="8">
        <location>
            <begin position="68"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR028998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="180" mass="21051" checksum="E8A4CABD69AAD866" modified="2024-05-29" version="1">MNYVKEEELAFLAENELIIVAPTVKLPILYLMGNNYGPFQPPLKEKVPIWLAILLRNRNKCRIVPPEWMKVEKLSDMLTKKNFKSLPFQYLEISHLLLGCATADIPNSNTILTLIREIYEIRKATFRAKIKDLNSDHMLIEDLGMMEINEFRPFVTTSFNHIRKLNDSYKKKDDDSDSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBK3</accession>
    <name>A0AAD5UBK3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone deacetylation protein Rxt3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBK3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013951">
        <property type="entry name" value="Rxt3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08642">
        <property type="entry name" value="Rxt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="47126" checksum="24F4C05D6F588C3D" modified="2024-05-29" version="1">MNSSQPKNNLPPLVGNTSNANVSLPSFSRISQSFSQQRVGEFPDYYKNRGSISSPSTSRSSPFASTSQFSYNSNFQQEKEVNVIPKSSSTGSLATFNLPGIQSLKYAYPTSSEITHVRSKSLSNESQNEPNSYLSSSFQQQSSEEVQFGKENNILSNQLESAVNEEINNINSNISVKASTKRKREGLELSSGLTRTDEKKIEFEKLKEEARRKKYLGEVPVINDECLTKIPEETLTVESSKFKNKTLRKTIGPIIYTGAKVRIPFSTKPSDLELFLLPIFTRKDFYSTVEIKIPAELLLFSTNVALRVCAVWGTDVYSDDSDIVAAIVHSGFYRPADVENPFKLLTEPFNQPVKQTVIGEIDSTDNLPDHDLLVVIMVLPRLVKYTGSIQYGMKSRGWGEHNGESFKIQNVSKIKKGLAKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBS7</accession>
    <name>A0AAD5UBS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_000027</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="549"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="960"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1067"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1248"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="292"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="647"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1067"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1340"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1466"/>
            <end position="1488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1467"/>
            <end position="1488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3228472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1628" mass="181988" checksum="C67540B2A2A30B04" modified="2024-05-29" version="1">MNSDWLCDHQPFQIWDGNLVNPCFEKVILNSALPASILLLSVLISLLCSSRNSYHRSRGYTPIASSSLNNEVRESPEHIESKKKNIFRLSLLSTVLLVAQLTLSIISYHKGTAKKLGNSDLIYYVSCICLWAFPLIISTLSTIGVLHKPTIVHFYPNFIFALLAQLFILRHLNDKAFAVAQIVISFLLIASELGQRFLDSYVEPLPADGDMTNRPLCLEENASLFSRAFFFWLTPMLRIGDRRPLEEADLWELSEIDRSKHVINRFHESKKISNSIYIRLLYVVWKPLSVQMCCGVITAVLSFAGPYFLNKIVSWIEKPDDSLFGPWGLLISLFSCSVLKAINDGQMFFLGRRVGLRLRSILVGEIYSKALRRAMTAGAAIATEEVMEENPDAELTADDVKEEEKEKLLKEKVASEEPVKQQASQGKIVTLMSTDTENLRTFFSYLHDALIRLPLSVIISFVALYLLMGWSAFIGLGVLIVLAPLTAYVSKIANDIQTDLMEATDNRVNITNEVLQGIRIIKYFSWEPQFNERINKLREIELRKFVHNWLIWATFGLLSYGSGILVSISTFATFTLIQGERLSPSVAFTALSLLHRLSRELGFIPMEFTHILQMKVSMDRIRDYLAEVELEKYQGDIVRNEEELDTIGFKNAKFIYHGSVIDPALDTNTFQLQSLDVEFPIGKLSVICGATGAGKTSLILALLGELNRVNGECFLPDPRLHAFNNPDAETGLIPRSTSYVAQTAWMLNATVRDNILFGRPFNAKRYFEVIEACALTRDLETLDAGDMTEIGEKGVNVSGGQKQRISLARAAYSPSSIILLDDPLSAVDAPTARHLLYKCIKGPIMAGRTVILVSHAVGLVLPKSDFAVVIKNGTISDKGTPAELAEGDALMGILSEDVLARGSDAILEDLDTNSKEVNDLYEEKEPHTLEEKSKEIERKAQGKLVQDEEKASGSVQLGVYWSYFSAAGGIKFLIVFVLSYILMFGSDVNLAWWLKLWTDSAKKVGKDTVAATPALFVMPNTNQLSKSLFFSSLMSLPSNAVSSLSSNSSKLPASESDYADTVYYLKYYALFGFVVMLCQNINMVVQLYSGIKAARNLHKKLLETVLGAPMRFFETTPIGRVLNRFSRDIRGCDMEVMGALGFFCQTFFQIINIVIIVSFASPVFLLFVIPTLTLYRYVARSYLNTSRELKRLESVSRSPIFSQFSETLTGASTIRAYGHESRFMKLAESRVDENHRAFFYLWVSNRWLCLRTDIISACVVFASGFAIFYGNIGAGAAGLTLTYSLEFTEALLWVVRMHADMEMNMNSVERIQEYSCIEQEPPAIIENQRPPSNWPSAGEVEVKDLVIRYAPELPAVLKKISFSTKKFEKIGVVGRTGAGKSTLSLAFFRILPLSEGSITIDGIDISNIGLRDLRSRLTIIPQDPVLFSGTLRSNLDPIEEHDDAAIWAALRSVKFLESLQDNKDESQTLNDEVSVTEDNASIKSGSSRKSTTQISLDAQVTENGNNFSQGQRQLLCLARAILKRTKLIILDEATASVDNNTDTRIQETIREEFRESTLLCIAHRLRTVIDYDRILVLDRGEIAEFGTPHELIERGANGIFRSMCEESGEFTELCDLAKAKHQSLLASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBV9</accession>
    <name>A0AAD5UBV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBV9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="331" mass="37084" checksum="EB9E6334C8D75C95" modified="2024-05-29" version="1">MYLFFEITLLRCIVLLLNLISLLFGVYLSCKNKVKITYASKQSIYRFSALSAIALTQCLHIPRQLLAYHHFPVYDNDLHIITKIVDWMSTATLYGSYCTVALGTIDRYRHIQLILPKSVSGGILDSMCVFTVVLSLVVAIYSCLENTNKVLCLVLRAFHPFWVVTVEYTLNIHMVVTTLINVKTMTNGKVNQQNISNSSSRTSRKSMCDNNEKSIAATTSGEFSESIVATKAVALKKMEKKLITTLTSLIVVDIVLIICYLLGCFVYLDIGSELAFIVSEISVIHVYISFQLLTLFSREIKKTNVKKPFSKNSSPVNEKIIVTTNSLGIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRX8</accession>
    <name>A0AAD5XRX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001513">
        <property type="protein sequence ID" value="KAJ3202857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRX8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="88" mass="10002" checksum="9046B7EFCB4C0104" modified="2024-05-29" version="1" fragment="single">MRKEWTPLNVVNSPLTSCTSPNSIDSLPNETEFNFSGLNLSNQYPLDLDEIENILLQEFKLSKISKTSSFNYNSESNFNKYNANIFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS10</accession>
    <name>A0AAD5XS10_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Leucine rich repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001789">
        <property type="protein sequence ID" value="KAJ3201057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS10"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051071">
        <property type="entry name" value="LRR-bact_E3_ubiq_ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47114">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47114:SF2">
        <property type="entry name" value="OLIGODENDROCYTE-MYELIN GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3201057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="43850" checksum="58E0A7CC091BD3E9" modified="2024-05-29" version="1" fragment="single">CLYQQGVSKLENLPTHLTTLDCSYNIISEIPSLPTFLTSFYCYNNQITTIQNLPNSLTKFHCNNNKISEIQNLPDSLIVFSCYGNKLKKIKNLSTSLIEFNCSSNKITKIENLPIPLTKFDCSFNKILTIEGLPTCLTEFECCFNVIFKIENLPGSLTKFICEGNLISKIENLPSSLIEFNCKGNKITKIENLPKYVIKFNCKGNRILKIENLPNTLIKFICGGNKITKIENLPNSLIEFNCKGNNITKIENLPQSLTKFNCAHNKISKIENLPDTLTEFYCEKIESSKIESLPLSITKFVFTLSRIKYINNVKIDRLSSFSLIGYQATKRLQNRIKRRFKKKSLAIRKIQAGCHSWIWKPVCKDGSYGIQYRVGVKALQDYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSC7</accession>
    <name>A0AAD5XSC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001414">
        <property type="protein sequence ID" value="KAJ3203546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSC7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="137"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="208" mass="24077" checksum="8A700CB8A8FCE190" modified="2024-05-29" version="1">MNFKDLFSIFKKPLVKKNVVKIENSNLSFLNVNFVEKNAGLEFMGKQENGLQVGNAEKIVLNNQKKTLVNPDVDRRNYINILKESLKSVENTKKEENSSKKTCHINDDRRKNVDKFKALLKPTQKDIVDITPNVIMNEKQRLLVNQLKNSLKSVENVKNETEGVESSVKNLKKLSFEDLKNLNSLEIEYQNDDILYRCIKLVIFYIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUB3</accession>
    <name>A0AAD5XUB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="18">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ATP8A1</name>
        <name evidence="21" type="ORF">HK099_006460</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 18">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 18">Membrane</location>
            <topology evidence="1 18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="18"/>
    <dbReference type="EMBL" id="JADGJW010000559">
        <property type="protein sequence ID" value="KAJ3215202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUB3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000087">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF174">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 17 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 18" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="844"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="880"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="938"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="993"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1023"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1067"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="19">
        <location>
            <begin position="74"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="20">
        <location>
            <begin position="817"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="20">
        <location>
            <begin position="959"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="15">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="533"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="613"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="614"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="615"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="734"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="740"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="790"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="793"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="794"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="794"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3215202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1210" mass="136471" checksum="F795AF52395ED96F" modified="2024-05-29" version="1">MFVSFSMLREAYDDYHRHLHDSKENHTYVQRLKFSSTKSSSGLLGSLTKKKLSLNRPKSEQIFSSGDLNNGCLSWEIVYWKELSVGDIVKVKDKEFIPADLILLKTDNCDGICYIETANLDGETNLKQKQALPVTNDFLVDDVKLMHLKTQIHAESPNGNLYHFEGYLEMGERYPLTASQLLLRGSTLANSGYIIGVATYTGEETKIRMNANEEIRYKSPMVDQTTNKIILAIFCSVLTLAAISTVNMVAWNVSDPWYLRETKNPVTTFFSFVILYNTLIPISLYVTLEMVKLVQIYFINHDLMMYCEASGRCAEANTSSLNEDLGQVQYLFTDKTGTLTENIMIFRKMSSLGLSFSLIDDPKSTLYSEKDFPAKNFIEDIKKLSMEDLSVNFELGVDFLRAIALCHDCSLQKSTEENTLAYQSSSPDEVALVSGAKQLGFTFKSRIVDSVTVEFEGEVGEFKILNILEFSSKRKRMSVIYRFPDGKIILICKGADSVIIDRLDAVFRKQGQSKELFTTSLEHVSRFATEGLRTMLYATKEISETDYEVWSTKYKEAAVSLENRSQLMEALEDEIENDLNFLGATAIEDKLQFQVPETIEKLQRAGIKVWMLTGDKRETAINIGYSCELIKEYSELILFKSCNKEELNTCINNATQTLLDLKTPEQQGILSHPSKHVVAIVDGDSFLVMQQEYIKVVEDVGKSNSSVNKGLLEETLLSKFFRLAVTCSNVICCRFSPSQKSFVVSNVKNMLKKSPDGVIGLYSTPRSFLYSVINVFKMRKVSGVTLAIGDGANDIPMLESAHVGVGITGREGLAASRTSDYAIAQFRFLQPLLFVHGRYSYQRVALFTLGTFYKSVTCYMCQLFFQNWAAWSGTSLFEPWTLSVYNILFSSLPVLVVGMFEKDLNISTLLNVPELYRSGQVNHYYNIPLFIRWVCQGLIHAAIAVIVPFYCYNGGLAYILNGTFLSNRSFGSANNFLQQIFFSDATGKFSESSLISIGTVSYTLVILLVTMKISFLESHNWTIFTFLAAFFSIGGWWLFQAIYSIVWPYLGEFGYDSLGLIFVLGDIQIQIWSISILGSILGLVLIDLNFNVIRDLWVSPWHYVKTDLQRESLKTLLSGNESPKSPYILDDSENENNKKTPLTFLNCSKAARAVCKAWKGEDLTYAAAWFARWESIHNIGPLSPFGLKKKSATIQHHETGNQSCLTKTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVB0</accession>
    <name>A0AAD5XVB0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_004912</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000362">
        <property type="protein sequence ID" value="KAJ3218836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVB0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004741">
        <property type="term" value="F:[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042255200" description="PPM-type phosphatase domain-containing protein" evidence="9">
        <location>
            <begin position="21"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="10">
        <location>
            <begin position="397"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="11">
        <location>
            <begin position="510"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3218836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="909" mass="100553" checksum="B6861A37C482A86B" modified="2024-05-29" version="1">MKRNFATLLLTLYFSQLYHSQITVDPPPITTTSEPPITTTTTSSCVVCPANPNRPCAGSVSTIQTADCDNCLSTTCIVPETTDPPTTTSSRTSSSTTTKISSVVPTKTSTSSETCTIEDTYSVPANNFINLATYDNLLNSPGVNPRTDIFWKTLSKNCPAEAMNSIILNTAFITTYFCYQDISLNSKPNASIADSLCTINNVNLPKICQSTCKSVIDSIKAFLSQAENINLCPNLDLNASLNQIYDNCMTYSSTDANCVGSISLESKNSCGFKSTAVQAEYCRINKNPACCIVEPPPSNFPLIVGILVAIGVVLLGVVLVLTCAKLRSAKTDDDEDFLKTPVLGNGSTTGPPSTTGGYAISNYTNRPSTLDRNMANRHSLNLAARPATLERNQANNNQIKKYTVLQDYLPNASDELDLRIGDVVLLNVVYNDGWGHAYNETTNMEGALPLGSKKLLLASGLLGGSVIALYYKKNTKSTINNQLELNPSANSAKNSSVDQFLKKNEKTLQNLHFNTVNSNDPCEDRYCESYYKDNLILGIFDGHGGYQCSEVVSKNLPLYIAKELETIKNTKENKNRKDAVTKALKNAFLNLDHDLLIGNFTDEKGNFFKPALAGSCAIVAYFDGEKGEDLYIASTGDCRAVLGKRKIDGNFEAIQLSEDQTIKNPHEYGRKQRMLELHPEELNTLFVKGRVLGGLMPTRAFGDARYKWPLETMVPILQQTPNKKGRGRSVPPNYKTPPYVTEPEVVHYKITQPHLSKNINGEDVLTGDLFLLLACDGIYDELSSEEAVECVNRYLQHSSLLPTSKNMLQKDKNNNLLPKYEFKKDENCMTNIIRNSLLVAAREDNLKKLMAIPAPNCRRYRDDMTGYVLFFNNGQNFNEKIENIEEVDLKNFNNKKSFRIAKFLEENKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVF8</accession>
    <name>A0AAD5XVF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000340">
        <property type="protein sequence ID" value="KAJ3219402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVF8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF11">
        <property type="entry name" value="OS06G0360300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="248" mass="27940" checksum="794521D80DC64495" modified="2024-05-29" version="1">MTTKPIFIIGGTGRVGRQVLEQLLSNGNEVKALVRSKESEVLKDFLNNPKLTVIEEKDLLSLSTEDFSKLIQDVETIICTLGHTSVSAKPKTLVVDTTKLIHKSVEHLKPSVPVKLLMLGTSGILNPADDRKMGFGENFLISSVKYLVAPVQDSQECVDYIANTITKDNQYLQWTIVRPVNFVEKYEDGITEYKTFEKTIHPFYNNGVVKIKNIADFFVNLVKNNELFDTWKGKMPVIVDSDQALYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW71</accession>
    <name>A0AAD5XW71_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SNARE-binding exocyst subunit S6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEC6</name>
        <name evidence="8" type="ORF">HK099_007786</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000790">
        <property type="protein sequence ID" value="KAJ3212200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW71"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051601">
        <property type="term" value="P:exocyst localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18089">
        <property type="entry name" value="SPOUT_Trm10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.70">
        <property type="entry name" value="Exocyst complex component Sec6, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010326">
        <property type="entry name" value="EXOC3/Sec6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042532">
        <property type="entry name" value="EXOC3/Sec6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21292">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06046">
        <property type="entry name" value="Sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="7">
        <location>
            <begin position="808"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3212200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1021" mass="118812" checksum="02E09B6283CD5520" modified="2024-05-29" version="1" fragment="single">MLDEDNFFSEATEAAIDRISDYLKHPDDLTNKFAALKKKLVQERGNIDAQLKTAAESQFEEAQKGLNALQFSKNETLKVKQNLTNIDKFCSDAQASISNYDKIKRISTTHQNFLATKEMVEQFQQLNSQIYRIKNLLQEDSQNILGSHDNILFVHHQLFALEDFRNRTLRKAKSSPADVLNTLHNYFKKIDVLILEFEDYLWSVARNTLELVKNKNRPAVVRMVKIIELEEKADEEAALMENSLFSEISENPAEADLIKPRTIKSYRIKFFDVLREGIVSHFKKLYEGNKSNLQSFLDGVDVVVDDLILVFDELAPCFPSRYNIFQFFVLEYHRIVYEMINKFISGSMEGGAILKLLKWVRDYYQNMSGRLGVGEELLEPRLLDGREEELMSAYVKLVQGKLNEWLHNLLISETKEFLTRDHAPDGDATGIYMLSGSVIVFQMFNQQIDVAASSSKGPLMKSVVFECVNTLIEFQQNWLKLMDSEYKKFETKASDLNEGLPEYIMALANDCYRSTEFSETMCSRLESVLDEPWRTQAIEKVKQGSDGFMNVAKKAYQMLLNFAITDSKRGLVLIHCSQWYEQDIMRMVIATYEDYCNDYQAHLSDYLFSKLTSDLLDKFVLMYIETFKNKGAKFKMPHAPEKMKKDLALVENFFLTLKPEKRVKKNLTEIVEKIINFIEANFETAFLDFYTIWKSFPDIPLAFIEDLLSRRDDLSKSQVKEIMLSCNEKVKDDIRSENFTPSVFSKLKLLKLEKRKSQSKARNLKNDLKIKETLKLKQSAKSLKLNSLKSIEERQKFLDDMKFEKLTIEKDLIFAKLNGIKVFVDLSFTKTQSLKECNSILKQLSNFYGSFKNASRENKLISLHLTHYSGEIQNVGKYFGVQNWFIFNSESNLEVNLNTFSNSNKKRKIFFYLTPDAEETLPLNFNEFFDDNFESVFIIGGIVDRSVRKNETLNRKFDFIGDVQDFHDLKVPFTLCRESIKFVKLPLKNFGYKNIVLNIDTVLHILNDFFFFKNWETVLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW78</accession>
    <name>A0AAD5XW78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4-aminobutyrate--2-oxoglutarate transaminase</fullName>
            <ecNumber evidence="3">2.6.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GABA aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Gamma-amino-N-butyrate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003617</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23352"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="2.6.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.19" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000239">
        <property type="protein sequence ID" value="KAJ3221290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW78"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034386">
        <property type="term" value="F:4-aminobutyrate:2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000073">
        <property type="entry name" value="Probable 4-aminobutyrate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206:SF1">
        <property type="entry name" value="4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43206">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="410" mass="45979" checksum="43F31DEEB83142A2" modified="2024-05-29" version="1">MIKSLGRLGKIQDSRSAMLVQDIEGSVGNYIKDVDGNVLLDVYCQIASIAIGYNNPGLLNLARSEKWVRASVNRPALGVFPPTDWAETLENSFLRVAPKGLNQVFTAGCGSTANEIAFKAAFMYQQTVRRGNKDFTAEELESCLLNEAPGSPDTKILSFRTGFHGTLSATRSKSIHKVDIPSFSWPVAPFPDLRYPLHENVEYNHSEESRCLDATEKLIKKWDSQVAAIIVEPIQGEGGDNHATPYFFKGLREITKRNNVLMIVDEVQTGAGCTGKFWAHEHWELDTPPDFVVFSKRLQSAGVYHNLSTRPPQPFRNFNTWMGDPIRAYQAEFMINEILTHNLAENATVVGEYLKEGLNKLSTLYPTQVSKVRGQGTFIAFDCENTEIRDKIALSMRQHGYDILMIFHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWE3</accession>
    <name>A0AAD5XWE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000210">
        <property type="protein sequence ID" value="KAJ3221765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWE3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3221765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="306" mass="35726" checksum="0A55D8EB315EB87F" modified="2024-05-29" version="1" fragment="single">MILCNKPSVSRSARFSLNLPVSGFGGLQEVNYRHSFCWTEDQENLKFLKEFEVEESKTYEEVVENILKLENSIGLYEEEISQDLKVLLESLKEIFCTENFRLTDLAMELQKPFQVVVNMRFGLTVVKKMLKKKNLESLNGSIKLIKDLLKKIYFKLDIQDDFENLSDLEEKLVYKYCVPLYDFPVSLPMTLNLKKPNLASEVNYLLDSPKIISRTECQMRNNNFNKNQIFEMILLTDTLLICQKFGNGKEEKLVLKYPPLPLELVRTRDVETKVGMAANLIEFMMSSKEFNELVNFLTKEQFETLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWS6</accession>
    <name>A0AAD5XWS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000611">
        <property type="protein sequence ID" value="KAJ3214557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="279" mass="32095" checksum="6E1C5552CC7E2847" modified="2024-05-29" version="1">MNTKESAANFNSADLDFLESLASDKPKKLNLTSSQLSFKNPFGDENQLTLDNLNLNNDKSFKAFETYKDPQYQKSTDIQPSVSKNESIKNTTTHIKDDTSVSPFYPSHWKPNWQLEIDLSSDYIKSVEEELNLKTLDFGFFFNILKCAWEDYETQQKLKTSPTGKKSKELSKKTETETIVEKILNGEKTLKDPIFDLKAKDVGDESNEQRRGSLSDNYSFKPFQKILKNLKEYYVEPSFISGDCIVIPSKPLQLEFTDNLNLAMFYIEKGYSLNFLRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWV3</accession>
    <name>A0AAD5XWV3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAM50A/XAP5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000942">
        <property type="protein sequence ID" value="KAJ3209407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWV3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048337">
        <property type="entry name" value="FAM50A/XAP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007005">
        <property type="entry name" value="XAP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722:SF0">
        <property type="entry name" value="PROTEIN FAM50A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722">
        <property type="entry name" value="XAP-5 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04921">
        <property type="entry name" value="XAP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM50A/XAP5 C-terminal" evidence="1">
        <location>
            <begin position="162"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="30433" checksum="77BA8C745052BBDE" modified="2024-05-29" version="1" fragment="single">MGDFNSGAQLKEALDKQRERIFQETQRKKVEIQQKNKVVIGKEKFVAQSDFLESELKTKTYGLVALRDFQRIKDEVLKNESKKGVDKKRKKLKEKVKISFDNEDEEAGVEETADNTAFKKLKKNPTVDTSFLPDKEREEQEKKLKELELVKWLEEQEIIKAETISIPYTYWNGTGKNREMKCLKGDTIGKFLENCKNKFPEIKGINPENLMFIKSDIIIPHSYTFYEFYLKKTRGKNGPLFDFEDVKNQKIKDLSVAKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXE0</accession>
    <name>A0AAD5XXE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Adenylyl cyclase-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CAP1_1</name>
        <name evidence="7" type="ORF">HK099_000936</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The N-terminal domain binds to adenylyl cyclase, thereby enabling adenylyl cyclase to be activated by upstream regulatory signals, such as Ras. The C-terminal domain is required for normal cellular morphology and growth control.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXE0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008179">
        <property type="term" value="F:adenylate cyclase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019933">
        <property type="term" value="P:cAMP-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.330:FF:000001">
        <property type="entry name" value="Adenylyl cyclase-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.330">
        <property type="entry name" value="Adenylate cyclase-associated CAP, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001837">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013912">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013992">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018106">
        <property type="entry name" value="CAP_CS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053950">
        <property type="entry name" value="CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036222">
        <property type="entry name" value="CAP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652:SF0">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08603">
        <property type="entry name" value="CAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21938">
        <property type="entry name" value="CAP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01213">
        <property type="entry name" value="CAP_N-CM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101278">
        <property type="entry name" value="N-terminal domain of adenylylcyclase associated protein, CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01088">
        <property type="entry name" value="CAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="6">
        <location>
            <begin position="222"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00054756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00072052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="408" mass="43853" checksum="68DD672F24AB68EB" modified="2024-05-29" version="1">MESVLARLEAATARLEKLSNQGVSKSLNEVATESTSTSASVAAFQEIVSGSLAEFLNDSAKLGSLVNEQANLVKAAFNHQLAIITTSSKSKKPADQKVLQDLTKPLSTTIQQIVELKDKNRPSKLFNHLAVVAESIGALGWVVVEPTPVPYVGELKESGQFWANKVIKEFKDSDKSQVEWANNYMNLLSELQSYVKKWHTTGLSWNPKGGDASTADVSKVPPTPTPTPVPAKPTVAGAGLLAGLSGAVSGLRKVDKSEMENHNNNPSVIVDKTEIRHVVYIYNCQNSTVQITGKVNAVTLDNCKKVGLVLENVVSTVDVVNCKSCKVQITGKAPTANIDKTDGLQLFLSREGLDVEIFTAKSSELNVVFEDPKVAPGSADYIEKPLSEQFKTKIVDGSLVTVPVEHTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXM0</accession>
    <name>A0AAD5XXM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXM0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="57"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S12 Pab87-related C-terminal" evidence="3">
        <location>
            <begin position="416"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="58770" checksum="F141F29DB9838DAF" modified="2024-05-29" version="1">MSNSVSNVTANAKEISTEVPVSTVDLDLKIRLIPKDLFELEQKIEEIRCYFNPQTALSVAIVKDGKVFLTKGFGPKVPNKPEKVDEKTLFNIGSVTKSFVSLIIASLVSEGKLDFTSNVKKIFGDFNLVDAELTEKVNLIHVLSHQTSLPRHDEIYLLKKRLEISDLFNRMSQFELIPEGFGKYSYSNHMYTLAAEISSKVNKKPFPETLREKVLKPATMNDTILWEEVADKSNLNIFTAAALDFDALSDSQIPEKFTALPFSANDDLFTGCGGLLSNAVDMAGYIQFLISRATGSLIKDAEFAEVFKCHIERNNKNKDHYGLGFAIGEYEGNLSWSHGGAVFGYMSMLRVLPEKNLGVFVAANGDNFGLLCAADVILDALLEIPFEDKKNHPELQSKAVAERMRLLVEEVAKTKKSDKTMHQLDLSKYAGNFYNPAYGKFSITINNSSKKIEGKLLDSTFFDFIHFDKEEFRCKVLYPNVNWAAQTFFNRKTCWFDLEDGEVVSVRLDLEPQLEKGVLFLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXQ2</accession>
    <name>A0AAD5XXQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005276</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000400">
        <property type="protein sequence ID" value="KAJ3218010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXQ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000017">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="WW" evidence="9">
        <location>
            <begin position="181"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="9">
        <location>
            <begin position="248"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="10">
        <location>
            <begin position="337"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="10">
        <location>
            <begin position="371"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="68"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="148"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3218010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="572" mass="63816" checksum="FD6BA1DE8B226C05" modified="2024-05-29" version="1">MKNQGFLGTATQNISEVFRDGLERGGEEMVTLDLKKLNNNDAVSGKLILHITTKFIPDPSNRTLLPGATYPSTPHVNSNINSARGSSSSLDGPSNQPASTVIPKQVITPNPPPARPSFINEDNFGPLPIGTPATQEVARQQHLNRNLPDSASIHSNSSASVIVSPTPNPSVVHSTSSSNLGPLGAGWEQRFTPEGRSYFVDHNNRMTTWSDPRRNQAATPATTTTPMNASQTATQLALAQQQAAATLGPLPGGWEMRMTSNGRVYFVDHNAKITTWDDPRLPSSVDASVPQYKRDFRRKLIYFRSQGLMKPVPGQCHVTVRRNNIFEDAYSEIMRYSPLELKKRLMIKFHGEDGLDYGGLSRENSIDGVLDMTFDVEEDKFGEIVSIELKEDGKNILVTDANKEEYVRLMCEHRISKRVEEQFAAFLSGFNEIIPSDLIGVFDERELELLIGGIAEIDVDDWKKNTDYRGFTENDEVVQWFWKCVDSFEPEKKARLLQFVTGTSRIPVNGFRDLQGSDGPRRFTIERLGDTGALPKSHTCFNRIDLPVYKNYETLVTKLTMAVEETVGFMQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYP7</accession>
    <name>A0AAD5XYP7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000465">
        <property type="protein sequence ID" value="KAJ3216675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYP7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.790:FF:000001">
        <property type="entry name" value="50S ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_uL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="28201" checksum="F6FDB74FCED15A7E" modified="2024-05-29" version="1">MQSPFLLSQKRHFDKKKFFKLKKAFKLQENAENVSFKDSIDVLRTYTMGEDLPTTIHLKIKKSDSGKILRGEVNLPNQLVEGDKGDGSTILVFAKGEAAEEARRLGAHIVGGEELVKEVSEDKHVFQKVLSTKEMYPHVVKIGRYLGPKGLMPSPGKGTVNDDIASMMQTLKASTKYEMDEDGFVHLEIAKTGWKDEKIIENIKSLMESLNVVKPAKTTLKRLIVKIGLSSKYSPGVIFNRAELVPSEILKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYT7</accession>
    <name>A0AAD5XYT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000448">
        <property type="protein sequence ID" value="KAJ3217022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYT7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="71" mass="8219" checksum="818DE7B412D79621" modified="2024-05-29" version="1">MDYELKNQATNSNSDVSSDEQEDFSDREDLLLHKSYDPSLYENIENSIEHGLFCLNYSNKLKSKKNLAKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYU7</accession>
    <name>A0AAD5XYU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005597</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000442">
        <property type="protein sequence ID" value="KAJ3217141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYU7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026124">
        <property type="entry name" value="Sperm-assoc_Ag8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15510">
        <property type="entry name" value="SPERM-ASSOCIATED ANTIGEN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15510:SF5">
        <property type="entry name" value="SPERM-ASSOCIATED ANTIGEN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22584">
        <property type="entry name" value="CFAP143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="194" mass="22548" checksum="C1B0015D1EB0BACC" modified="2024-05-29" version="1">MIIKNGTDWNRHHGNGATLLENWVEERAIDPSLHFEDREKNYLKRAHKGILSEGKAFPMKTTSQESYTKKDDEIHKITIGKKRLQFETELLMRAVKDMEEKVENRTAKDWISTNHQDFAHSDIYGEIKDLGSVPPSEDDLEKYKVPITFWSENGKFGEKYNLEFDGTVKVPSLTFKKDTTFSTPIEENKKTSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZC2</accession>
    <name>A0AAD5XZC2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YABBY protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000488">
        <property type="protein sequence ID" value="KAJ3216259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZC2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056775">
        <property type="entry name" value="YABBY_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04690">
        <property type="entry name" value="YABBY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YABBY protein C-terminal" evidence="2">
        <location>
            <begin position="44"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="96" mass="10179" checksum="0794B2F6F9C30325" modified="2024-05-29" version="1">MAKVETMTKAETSKKEKSSSPAKETKPKATTAKPAAASTTKKAAPPGGKKVNPYNVFMKTEIAKVKADDSSLSHRDAFKVAARNWAGSDKNPKNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZD6</accession>
    <name>A0AAD5XZD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006026</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZD6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050872">
        <property type="entry name" value="PPR_P_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128:SF181">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="351"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="456"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="560"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3228146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="825" mass="95675" checksum="6115B911A38A3FBA" modified="2024-05-29" version="1">MHLTVSRINFLIHWVQNVGLISKKNSFCQFSNCRSQEKNNVSQKERNFLKKKHILSRSKKKNKFNKHIANAKDPPKNHHKVSETLENSDVPVKIDFFENVTNKHYGKKNEKIERNLRDLNDTIIEEIASEGTLNLNKYVQCAYKIEKGGVIRKGNINRDINKIAKKDVDTSCFRNYSKFDTNRAQKVNLINRVSGVLDRNFHTKLLMKPDTAEKKFREDKCSMLQAYLQQDNPDITKITTYFEEAIKFFGSFNPSTIALYLKFLCKLNLEKELITAFSNLRAPNLIHYTIILQYFSNKSKKAVFFYFFKKLHKTGWSCNVAIYNALIGLQESISAMDFYFNELKSNGFAPNLTTYNLLLKSASSLGMMNKCADYYEEMMKNDITPDIKSYTFLIICCMKSINHEKMEFFYQKMKTSLVKPDAVFFTYLFNSIPLSRKYHRIEFYLNEMESSNVIPNVDTCNSVVHAYISANDIRNAESYLLKMKSQNIKPNASIYNLFLNTFSDDENYYKFKYYYKEMIQNGVSPNVSTYNILLKTLFENDGQKLLDIYRSLLSSGLSPDVVTFNFIIKYFASNEHHKATDFFFNQMLSEGVLPTARTYNILISSAVKHDFFKANQILNEMVAAGIKPDIITYNTIYLSDFTISESEFLRRLNLLSRLEIAPSITTFTSIMQFYSLSRNYLLALQIFHSVTGLRKNFNYVKFPLKLQEIELEDTKHSRIFFSVALDVCKLGNFKKDLFIVWNMALSSGVNLDSNVLTSYVEALCVFKEFNSAIKIVEESLCSTNIPKADKKTLEHLIMGLKDNGGLMEYNIAKFTLLKLKMILKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZG7</accession>
    <name>A0AAD5XZG7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005672</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000452">
        <property type="protein sequence ID" value="KAJ3216946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZG7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="6">
        <location>
            <begin position="50"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="237" mass="27334" checksum="C17EC3156F5A6544" modified="2024-05-29" version="1">MRRNSTTSKKSSKESTPLSSPETAKQNSVSQSTEVESNVLLESSLRRMHYQTLTGEKKYRLVIRQQPFHVRMCGSTDKDRRTLDPPPIIEILEVDEAGHLYPIIKDSAFYIMRVELWNEQKSEITLFKKKFVDLPLIIGDLVVGSKVLSDDLGRTGTFFVFDDVSIRYQGRYRLKFKFYDIESGNELDCLMPKAYVLSEMFSQEFVALTAREFPGMLKSAEITKHFKTQGLRLSIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZH5</accession>
    <name>A0AAD5XZH5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000447">
        <property type="protein sequence ID" value="KAJ3217026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZH5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052809">
        <property type="entry name" value="Actin_polarity_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012860">
        <property type="entry name" value="Afi1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245:SF1">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07792">
        <property type="entry name" value="Afi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08616">
        <property type="entry name" value="SPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="2">
        <location>
            <begin position="5"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="802"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="847"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1217" mass="138397" checksum="7B769983D7A8DD00" modified="2024-05-29" version="1">MTLVSHIFIAEFDIDKGSNLTYQYPTQTNYDPAQLADLMLPDGAHQRQEDWTYFFLNRDVVNDAANFFNALLNAGVQENSNNLKYKELPLPLTKIQQKCLTENTHFEEHKPFLHVINLVRTKFISGARRGAEVKALAIASQYSWVHIFKPLLVLGLEKFFNQPSELILKELFESVNKMIMDNFPFLTNYEKLILRSSEDETIFEEKFLYSQNIVNKSNNLVLKSTEENLENSNNSNIYNTTQQKPVTQNNLNQKKYDRHFFETKVDFDSITIPIRIPCSVFSEEIGDFSIIKLISIFSSTSSAILPLPNNSNPIKYRNGLPYQWHPHLDNGPNTHPITLLLNALICQKNVLFLGYGKPSAEVANFVLAACAMASCGGSLLRGFINRCFPYVSLVGIELLLQINGYIAGVTNPVFEEQNSWWDVLCNINTGKITVSPKIKFPNSTDKSGSNFKSEKLLDGGEEHVFDKSIQNDVTSEFIYDLVTSVNSHMPEFYVREKIYDFVERFVDLTSTYELETFGKSDISTKKEVDNLENDSDDGNSIYTLEKLVGSGTFFSSKEVKMKELTFFRNWFEGWRETENYLLYVKDFQTKLLRKSIRGIDAKHLISRLKSSETISDIDTVTIFLAIQDSVTSSSEQQLTEFLSFLPQSQGGVNNCIALGLIHRRWEVRRATVRIFARLSAHYVGIKFLHHLNPFFKIVYEKLGAELLVSELETLNSFSSDAEKVVLNSKINNSGERLTKFSILQRQQHQQEKGNPLNFGSTFSVADSYWEEESSRKNSTNQRSSPSFLPQDQHQPGIFGGTSSSSLSSTSYESIRSSSPHLSNLQREPVRHSLTRKILPFTKSSSDSNLSRTLNNNANATSNFNSLQNLSMDYPPQKSNVNNNTIPASNPNDQNVNRYRTNLKSPLSQESIGKNYSLATSSFTQQSKYNETTMVNSNAKSSLQYGTFNYNSQSVQPHPIILKRSSSENIFPQLQQQEQNNSLQEQKSPLKSGKIFDVFRSKKNSTNNNSVSNSNSSIVDSQESPPKAAVTDSSAVVKKLIEQQQMKQQLLMNKLKEVRKTEEDNSESSFQGELLVPFGGKEPPVSNSLGLKREREKLTSIPILQLPPKKKKDTLNLTIAENVVISKGFQEQLKDDKKFEILLKDPVKLPVQFNFEQEWEEIDKLTKSFENDFSFTPRNSKLSNKKSSVIYSDTGHNRRPSVEIFEEEVWAEESDDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZI3</accession>
    <name>A0AAD5XZI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004305</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000003">
        <property type="protein sequence ID" value="KAJ3228312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZI3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="86"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3228312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="127" mass="14349" checksum="7697901A6490D804" modified="2024-05-29" version="1">MKKGDGLIVGESLPKSGTCKHYKRSYRWFRFPCCSKLFPCDECHHELSLDCKENILANRVVCGFCSREQKFDAKNSICICGKDMSMSSAGKSFWEGGKGNRNKSKMSKNDSKKYTGLSKTVSKKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZK7</accession>
    <name>A0AAD5XZK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-directed RNA polymerase II subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPB7</name>
        <name evidence="6" type="ORF">HK099_007316</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000007">
        <property type="protein sequence ID" value="KAJ3228035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZK7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04329">
        <property type="entry name" value="RNAP_II_Rpb7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF4">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="5">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3228035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="117" mass="13211" checksum="D334DD5F17FAA83D" modified="2024-05-29" version="1">MFFAKDLYHTIALHPSYFGPKMKEYLVKRLHEEVEGTCSGRYGYVVAIIKVLEVGKGVLQHTTGSAEFKIHYQAVVFKPFKNQVVDGVVTTVNKLIPDYMKFDPNSNPPAYISEGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZX0</accession>
    <name>A0AAD5XZX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SNF2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000366">
        <property type="protein sequence ID" value="KAJ3218762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZX0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SNF2 N-terminal" evidence="4">
        <location>
            <begin position="395"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3218762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="548" mass="62589" checksum="CE5A5F4C99E85418" modified="2024-05-29" version="1">MSSILNETDDKNNKNFIYDTSIVPEIIKDSEDEEELALKEDNSDDNDDVIALNGVYYDDCDDDNNCTLNVPSDEDVILWNDEPCSSKDFLKRKLNSNETLNNEKRFKIDDFASKFSDNDIPTDNAANYNDISKIEPVSETYYISEFSDDDDILDLTTEEFTFSTKKKQETEVIDLTGDEKLAFSIQQLDLELEKQRKLQEQQDAEYALKLSLELNAEIPVETALQRNKIENSNNLVYPILSNSSFDDTSKEKLKEIERTVPFDKQNASIAPPLVKREWGFKSTVSPIVPTEFPFHLNPLTQQRLKQARMDAAGKRALATETPVFLSASTLMQLPSIIPPTQKTYWTPTVNNLQRSSNADDMVDSDLKNLLSNVAHNENITPINRRLPTPALMVRKTIQTIALLLSNKPTSDGTNDITNQVLIICPKSLLNQWKEEMIDKTNYFTEKSIHIYHNDSPGGKEKNLKILKQYEVVITTYGAITSEWINEKKIEKASNAKKKNKQIKDFFLDEEADKTKKSSKRPANRLGNLFQINWWRIVLGMIKVVGEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y035</accession>
    <name>A0AAD5Y035_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003738</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000249">
        <property type="protein sequence ID" value="KAJ3221142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y035"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042170676" evidence="1">
        <location>
            <begin position="19"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="19233" checksum="CF70338AD0C04384" modified="2024-05-29" version="1" fragment="single">MKFNTQIVFAALASVALTQEPGLPGLPGAVSPIPVLETAPQDCPPEVFTELVAANTPFVEPTAPINDTDPQALFQSIKLPPSIQKLSFAAVGETPILLVEFTNGTSCSTSQDAFLAQVAAFEAANGSVNTTAATNNVTTTLPILPTSSIQTTFAAPTATEVKATSGALRNFGSLSLLALSSLTYFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y058</accession>
    <name>A0AAD5Y058_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell cycle RNA binding protein whi3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">WHI3</name>
        <name evidence="5" type="ORF">HK099_003650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000240">
        <property type="protein sequence ID" value="KAJ3221266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y058"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="12"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="576"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="469"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="469"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="672" mass="74097" checksum="9D33FDF5677AD93B" modified="2024-05-29" version="1">MPSLSPTQEEITTIFVIGFPEDMQEREFQNMFTFCQGFEASTLKYPQNYDFDESKKQIIGFAKFRSRSDALNARDVLCGKKIDQDRGFFMKAEIAKKNLLVLKKSATFAESVTSTTTVTMASSTAPVSNVQTPPPSVNNVSSYSSASISKARQSSISSGSTSLNPTQTPVCNQFTSPSTFTQNSNFLENVATRESPTSELPGQRFSPDNSFIVNKDFSKSNDSFIHDENFNSDGYFQLPKDLLNGLDKLDSSVDSLDTLSSNLTNSSNSSVLTGDSLAGDSNTFTKGRSLLQKEKSFDSNLGSNGGSSNYINASRFHNLDNFIPRFENNYKGPENNVKSISTVLDGMNLNATLNSAGQKSSHFWDIYSNNTKTTVFNNNITKKNASSSAGNISHIQLQQDHITTTSGGIFNNGKNTIESKFFNSTEFSANNSLNDVSVNNSYLTNIGVGTVNDLMNDKLILKSNDQFHQQQGESNNFQNSFNTGSASSDRSRSLTPVTNGLISPPVTPVHNTFFGRFPNDSVYGQISQQQVQQQQQQQFLQHFQQVSNLPSQQQVPPIIPPTLLSTMQRDQNPPCNTLYVGNIPNLTNPEELEILFGTCKGYKRLCYRMRPNGPMCFVEFEDVLCATQAIKDLFGRPLSTHVVGGGIRLSFSKNPLGVRLNSQRGTSQPTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0H4</accession>
    <name>A0AAD5Y0H4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000279">
        <property type="protein sequence ID" value="KAJ3220711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0H4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018800">
        <property type="entry name" value="PRCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13621">
        <property type="entry name" value="PROLINE-RICH PROTEIN PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13621:SF2">
        <property type="entry name" value="PROLINE-RICH PROTEIN PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10253">
        <property type="entry name" value="PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="288" mass="32409" checksum="31F52988A15964C5" modified="2024-05-29" version="1">MNSLAEYSSSDDEDTVTDKSTQKRSSLSSILPPPKLAGDNSINNITSKNAQQQKRKQFFVVVDETEKEIQEEDNTNSKKIKINQETVKSTGLFSLLPKPKAVSKKTLQESPKTTHFIPNTIKKSSLPIKKEVDKVEDFFSFGEAEAVPEDNEPIQGPVYKPLTSASSLYTPDAYYSNQPQAPNDDFDDEKQNVIESVAGRKKNEIQYVEIKQSEIVGRWDEEKHKVSLTQQELARAHLATLKPVTKSQKKNHTIFSLAREAAINQAELLEAAAIRRQNVKITKAKYGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y211</accession>
    <name>A0AAD5Y211_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000910</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000123">
        <property type="protein sequence ID" value="KAJ3223618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y211"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04515">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.200.10">
        <property type="entry name" value="MHCK/EF2 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004166">
        <property type="entry name" value="a-kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052969">
        <property type="entry name" value="Thr-specific_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47763">
        <property type="entry name" value="ALPHA-PROTEIN KINASE VWKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47763:SF1">
        <property type="entry name" value="DUF659 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02816">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00811">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51158">
        <property type="entry name" value="ALPHA_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-type protein kinase" evidence="6">
        <location>
            <begin position="960"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="454"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="831"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="893"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1205" mass="134295" checksum="D15204236DC9836B" modified="2024-05-29" version="1">MEFFVNQYNKLVKRWQVTRSQLLRDHPEIDPSTNSKYLGRFNERVNHGGDINEFTMKNHAQTFSENHQNLSATQKAVVADEDSRTFAGLSHTSPLHSKSTDIPSNIHHYATTFFGNETISASGNFGASPTKPVVTHRPSNNGLDSSTFLGSGSYANNTAVSETSTNPLLYHSKAPEANTFLGYSSHINSLPKVNVPGMTSNGPPPVPQRGSNMSETPKTFDQNQLPPPVPKRNEASTITPGINSASTFIGNSGSSLLYGRNSADSLVRTNFNGPVGTSIGISGKNANHASGTFIGPKENNGNNAAATFVGTNENSVKSAAATFVGTSGHNVNHASGTFAGTSTNSVKYVASTFVGTSGNNVNYPTGTFVGTSGNNVNYPAGTFVGTSGNNVNYPAGTFAGTSGNNVNNPAKTFVGNNLNYAGSTFVGTSGSNLNHAATTFVGHNQPEGAANCKIKPSNTFVGNHSQRPPPPPPRVNLNKNATPSTSVNNQLGPNLSPGFAIRPSSPLVNAQESIILAKRLQAENLKHAERNRVQKMAIDCCFLMDLTGTMRVWIEQTKKTIVSIMNTLQEKYSVDTIIKVSFVGYSDYNNDTPPVSKTVWRRYDGEDVPEDVMSGLDKVLQLNWSAKTKILIHIADDPAHNKEFHDFRKGFDRYLDINDPSGRGPKELYQMLGEIANKGIDYHFFHLDDNTKKMEEKFDLELKKYGSKLSVHFIGDDPEGFVPQVLKVENLKVTEDLKDLNIDVQNLGKKLLLEKEREELNKIVLDDIDYKLNNLLVLRAVQLEAIRFHEKIVQYEASNVINAEIERKLIYEKISHTEDEEQELVKNFIDVTSLSKILKKLRDKKKILKEENLKLKEASKESFIKKKIVDIFNDFEIQVFELANPLMRNLKFYKEVNNKIQKDILEKQNIEKQRLALEERNLQDDHANKIIPWLISTNYEWDLEVNVTMEVFERTSANSIFDDIINNKHFKDICRIRKVNVFLRMMSKPFDSGTYRYAYYAMDQQGTKYVIKHFKVQEDFQNSEEKCASNTSKAYFVCGLLGNEFTQELSLIGIDSSIRYTPSWPAKLILANQKKPNENMEFFSQKTLMIERSSYVADGNGGELMSAYSHFTYARSKKLMMVSDNQGHYEEKMMDGGKRKELFVLTDPVIHVPDLNLSTAKLDSTPLLMDLSHPLDGNRRKDGINEFALTHTCGPICNSLMLKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y231</accession>
    <name>A0AAD5Y231_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000754</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000119">
        <property type="protein sequence ID" value="KAJ3223734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y231"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05379">
        <property type="entry name" value="CAP_bacterial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31157:SF1">
        <property type="entry name" value="SCP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042160632" description="SCP domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="3">
        <location>
            <begin position="57"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="327" mass="35932" checksum="4A105ED6FC457469" modified="2024-05-29" version="1">MSFKLATVFVLAIAVSANKQQTNENYTPTTPSNPNPPSGGYYGAAPPSNPQYCHLVNGVNQYRAQNGLSPLVGDSRLDDAAKVQCNAMAAYNNLDHSADGSRLGDRIEQAGYNWGGVAENIYNESGYGATDQQRALDGWINSAGHRANLLGDYTSVGHASCKTGNTVYWSQDFAKGSPEPAYQYSCGGDYEHKEPTYNDDNNEEETYTKPEPKQEIKEQEYKKEEEEYEEAPPAPVKKEEEYKEAPPAPVKKEEEEYKEAPPAPVKKEEEYKEAPPAPESKTVPEAEVKYGKHGKPCKKTTYGKKSPANDAEAKPYTAPKSAAYSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2C5</accession>
    <name>A0AAD5Y2C5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000065">
        <property type="protein sequence ID" value="KAJ3225300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2C5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF52">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="382"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="586"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="619"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="652"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="685"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="718"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="751"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="784"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="817"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1038"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="923"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1038"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1059"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1076"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1252" mass="140667" checksum="CA400A2A3EC79124" modified="2024-05-29" version="1">MNSRHRKVAPTEYIGNNSVKRPHSNVNVINHEISSSNSADEGGKVNLEKKKNASRSKEQQEELQLKKNVNSKFIKKRISGANAHKEHKAHSLPRNLDTPLSVRYQTLNSNLGPAEDNAMSRPASAPETFHTKKVPNVSYQRLPTNRSQKFNKNQNHYLENIQLSHSKLGFENDNFPTPRNLPLKKSPVSISPISEIHYNANSITGDELLDILAESAESAGKVVKSGSLEEDAFPLNKLDNFSGYHKPMPAANATEAIFNHLDEDTNFLTNEVGLNFSKRSVNEILSPLMDKVTTEKAYTQFEENKEHIMPTLEGKNSKDIYDEFNGKEYTIEKKFKFESLLQKLSLYQINVLLFHLARVGDLKSLKKLLNVHNLDLNLKDDEGRTPLFYCAIGNHEKSLHFLLKNGSIISNIDSSGRTAFHWACYYGCYNSCKVLFKYLTDSSLINSEDFQGKNFLHLSIYPEKSLTLKFLLRKCKLEVNQVDEEKMTPLMWATFYGNTDNVKLLLKFKGDPFLKDIEGKTALHWSTCNKHSGCCSTLLKFNPELANIKDNLGRVPVHLAAGEGNCAIVETLIKNEITKIGIRDNLRRTPLHWAAVRGHVACTKLLCDRGSNVNKVDQFGASALHYAAERNFRDCVHVLIKKGIAVDCNDENGQTPLLWAASAGNVGVIKMLLENNAQIEVHDINGLTALHLSADAGHTSCCVFLIQKGADVNAPDLKEQTPLFRASINGRTDTALALINEGADVNVNDRDGRFPLHWAASAGHFDVVNILIGQGANPNCVDFAYTSPLHEAAFQGRASVVSYLLQCGALVNAKDEFGITPLHRAAGNNQLECCQLLIEGKAKVNALDFEDVGTPLDLCLRNINYQCIQYLQSVGALTKYEVVLYSVKTIQKFWRKIKENQIELSRSNVTKKSNLNSSSKSGLGTQNRRVNSLKELNKDFEEKILKFELEKLNFKEERLKLEKEKAEFYKEKAAFEEELLRITSEKRKLQISTMQTSNSENPNINHKNNIKLIKKQQSEVLKPLNTIPFKMPIEQQLQQEKLQSSMSSSKKLNLSLSSEPEKKEDIDVNSKKSHHQQSLVNSATSNKLPVTANSLNYSEQQSDMDSNLQAELLSDKNVDANQRAATIIQKVWRSHNSAKIKGPTEDLQNTTKSNDCDVHSNIVNENLPKQKIRHDKLDKSFKGEQLLEKSKKEKAIRQLSKLDNCESENSASTYPIIPSYSETKNSEKMQATNSSLVSLMAVDELMKVYEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2E3</accession>
    <name>A0AAD5Y2E3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UBE3B</name>
        <name evidence="7" type="ORF">HK099_008545</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000095">
        <property type="protein sequence ID" value="KAJ3224373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2E3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000002">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000011">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF3">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="6">
        <location>
            <begin position="432"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="796" mass="92224" checksum="D0AA4608E88C5373" modified="2024-05-29" version="1">MVNKNNVNNLSFFNENLILHDLSKSSLHLKVTTFQIIHRYPLLLKKFIKILINRVNGVNEDGSLYLTGPEIRVLLLLLDQKQWTNQAISVTFFIDEDNCRIISTGIEKRLNAIWKMKLKYNGKNFTTPLNRESLFNLVLNQLAYLYENKTILMAFNPILHHKIKEEEGKLTSPIYNFLKKTDSGLMNLTLIFSNVAEVYLLFTKIFYQKKTMVLSNIAFIKDIILNSWNFLSEAGSNSNGIEILLQVKDLDREKLVPILELFCELGCLLYLTLDNDEMYVLETPLKKESLQKLCIFLNKFCFNYYWNNLGKTPPLFSAIEPMQRFLYLLCDKNQRQSFLPTPNENWLIIDEVKEKNFLKFIQEKEDSEQKIRSIKILSQLPQTIPFKTRVEIFRNFLTYDKETNSATTISGEIIIRRSQFLVDAFTALSRFSADKLKKTIKIKFISELGLPETGIDQHGLFKEFMSALCSEIFDPNLNLFSSTQGNIGTVIPSLTSSITAKVNGLNNLELFEFCGRMLGKALYEGIVIDIPFPLFVYSKILGRYCFFEDLPSLDEVLYKNLIFLKKYEGNCQDLSLTFSHEVDYFGEHVIKEIRVGGTDIIVNNDNRFEYLYLMSDFRLNKELKNEFDHLIKGFRSIINDRWLRIFSPSELMKLMAGEDTDFDVNELRVHTKYEGGYFDQHSTIRAFWKFLQKISSEDRKLFLKFVTSCSKPPVGGFRHLQPQFCIRYVSDGDENDGSVTIGGVIKSFVGLGKDYRRLPTASTCFNLLKLPAYRKNATLKEKLLYAIRSAKGFELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2H9</accession>
    <name>A0AAD5Y2H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Translocase of the inner membrane</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TIM17</name>
        <name evidence="13" type="ORF">HK099_008197</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2H9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="169"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3224588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="203" mass="21842" checksum="CAB7C1CB9BE47F11" modified="2024-05-29" version="1">MSRDHSRDPCPYNVVYDVGVGFLMGAVGGTIWHGFKGYRNSPRGERLTGMITTVKVRAPVLGGNFAVWSGLFNSGDCLIAHIRGKEDPWNAILSGFSTGGLLAIRSGTRAMAASAIVGGIILSVMEGVGVMINRLTLDSYKPVAPQLPDLLPQTLPPPPKSKIEKKLDNEISEEQSLQDSSSQINQISSLPLEKPKSRFGFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3F4</accession>
    <name>A0AAD5Y3F4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_004694</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>dihydroxyacetone + ATP = dihydroxyacetone phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15773"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; glycerol fermentation; glycerone phosphate from glycerol (oxidative route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000034">
        <property type="protein sequence ID" value="KAJ3226518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3F4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050354">
        <property type="term" value="F:triokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10440:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase, DhaK subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF4">
        <property type="entry name" value="TRIOKINASE_FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="12">
        <location>
            <begin position="6"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="11">
        <location>
            <begin position="412"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3226518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="615" mass="66539" checksum="8FEA023C4D79FAC5" modified="2024-05-29" version="1">MKFYNDATTVVDEALNGLINTNPMLSLLRKHRVIYRSDIAAVRDHEVTLISGGGSGHEPSHAGFVGDGMLSAAVCGDVFASPSASQVIAAIKTVRSNKGILLIVKNYTGDRLQFGKAAIRAKKDLNIEIKLLVIGDDAAIPKEKVKSVGRRGLAGILLCHKILGAMAKKGCSLEEIFFQGEMIAKNLGTIGVATSPCTLFGKTPVLFTDANVMEIGLGYDVLIDVNIILISIHGEAGFQKSAMSSSKKVVKTVLDMLIHNPMELAEFSDMFSNYFKLKISNADKVCLIINNLNSCTSLELGILINDTILELKSRGIETLRIFSGPLMVNVIKIHINSCVKTSLEMTGFSITILKLQNEDWLSYLDYQVRVLSWPFSQITAESWKISSKNRTKNEENETDKVKMLDIVTKNGKLFAKSLYLGCQALIKASPKITELDKIAGDGDCGESLSQGASSILNKISVDLNGDPKSSEFAFDNFSDALSSISLVLEDNMGGTSGAVYCLFLDAAAQCISEIDTEDTLAIWAKAFMGDCTLVDSLYPAIQSFQSGVSKNMDLQEILKECVKSAKEGVEHTRLMKSASMGRAAYQPEGSLEGIPDPGAFGVAVLIEEMTTIFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSU2</accession>
    <name>A0AAD5TSU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001938">
        <property type="protein sequence ID" value="KAJ3200270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSU2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="184" mass="21554" checksum="6E68F8E9991D5889" modified="2024-05-29" version="1" fragment="single">MLADNKNWFDQFFENLTENILQFDKNNFSIENLFLNQINGDFDKNLMCIARHHLSCSLFQPPSNNDISRLAFFIETISTRSDSYVSLALQVNMYSESLYKNFQTKVSCQKNEFDNFLHQKSVQQKIEFVVEFLLNHVTVFKPSFSVLQGLFNIFQKLSEEWGNNKRQQIEVASKITELANLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSV9</accession>
    <name>A0AAD5TSV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002533</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010001844">
        <property type="protein sequence ID" value="KAJ3200741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSV9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052162">
        <property type="entry name" value="Sensor_kinase/Photoreceptor"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304:SF1">
        <property type="entry name" value="PAC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304">
        <property type="entry name" value="PHYTOCHROME-LIKE PROTEIN CPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="62"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="108"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="178"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3200741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="340" mass="38829" checksum="0C8CC9C316B8B083" modified="2024-05-29" version="1">MIWKTDPTGKAINLNKNFLDYAGVAEDKIDTINVFSQALIHPEDFKRSSEAFKNAMKDNKQFEVTRRIKGFDGNFKWFLTRGTPMFDSKNKIQFWCGSCTDIDKVENFKLQLQTLPEVLPVMLWKINAEGDVLFGNKKFKEFSGVDPAKTTLNLFSADIVHYEDADKSRTVLVQALKKKSDFEVTRRLKGANGSYTWFLTRGAPEYNADGDVCGYFGTCTDIHVSKAVQDELLVLPECYPQMVWKSDAKGNVLFSNKKFTQYAGEDKKINVFSEMIVHPEDLRGNRDAFARATKEKNTLEMRRRLKAVDGSYKVHFSKAAPTFNEKGEIESWYGSDTVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSX2</accession>
    <name>A0AAD5TSX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nuclear segregation protein BFR1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001888">
        <property type="protein sequence ID" value="KAJ3200518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSX2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042175">
        <property type="term" value="C:nuclear outer membrane-endoplasmic reticulum membrane network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039604">
        <property type="entry name" value="Bfr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027:SF2">
        <property type="entry name" value="LEBERCILIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027">
        <property type="entry name" value="NUCLEAR SEGREGATION PROTEIN BFR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="417"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3200518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="471" mass="53777" checksum="BFC96ACA820AF55F" modified="2024-05-29" version="1">MSVDQKENKVDKKTDTKNQKYTSKRIPKPDEEAYKIATAECEKNINLLKEKLVAAQAKVTGGSSGNSKNEYEAKRAELKASFDKLFNEKKALENERSKVFDQIKKIKADIKKRGEEVKSSKDKLGVKSVKDVDVQVATLEAQLAGGKLNLSDEKKIVQEISSLKKARKVLDGFSAQESTFENDKKNLDELHAKLKVFDEKRKELNSLIDASRSEKNEFESNLKEKIGSLSSLYEARDEAKKNLDAEYTKVKKLRSDFKVAKDEFYQHLKAERERKNEAYQIEKQQIRDRKLTEEAEREREEAEIPAYTEEINQCETLIKHFNQYIAGSNDANGQTQAAAVNANIRKVDDSLPEGAAVLVKNKDREEDFMVMGGKKNKKNRKHEQIKENNTPVTKVLKLDLLLIDQLAKLKIEIPSSIKDVESTLKSLEEKKKFFKENQASKTLENKKKAEEKISLLKERANNETDVVETEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT31</accession>
    <name>A0AAD5TT31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002037">
        <property type="protein sequence ID" value="KAJ3199786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT31"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3199786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="166" mass="18378" checksum="3CF6A4B7EBEAD52B" modified="2024-05-29" version="1" fragment="single">TNSYGEIYGLRSAYDVCLVLWYKRTPIEVTFITACTITISGPTSFMAFAYYKIYKDVKDTGKKLNACFATTQAQSKLHDQESNDGKLSILGTDSVVGDNLNSKNRLHKDQADLEKIVLLQSISICFCFIVGWIPVIVIVSHEVISGTSAPVWLLHLNSFGPAFTCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTC7</accession>
    <name>A0AAD5TTC7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Homing endonuclease LAGLIDADG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001658">
        <property type="protein sequence ID" value="KAJ3201865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTC7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03161">
        <property type="entry name" value="LAGLIDADG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="1">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="145" mass="16673" checksum="3854680D9BB0B044" modified="2024-05-29" version="1" fragment="single">FQIDQEYKHKEYLDWLTNWFFIRGYCASIKPKTINRGDIKIVRLTLYTYTNLDWIYNAFYKINYSSSSSKSTKIKVLPSFVANFLTPASLAALIMQDGSRQKGQGVFIATNCFTFTECQFLSSLLSSTFDIKTSVVSAGVPQQWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTR0</accession>
    <name>A0AAD5TTR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001381">
        <property type="protein sequence ID" value="KAJ3203780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTR0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="1">
        <location>
            <begin position="55"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="253" mass="29106" checksum="3620C62806E81B8E" modified="2024-05-29" version="1">MTLSIDACYLRPTSLLLGTKDSYKESTAKRSKKLENFFGSAPPLDISVTDIKKNGLSAILLSRVPLAYFLYQILQEHSCENLFFLLEVDHYESTEFNSINHQRQAAHHICETYLSKNSHFEINVDQKISNQTIENIKSDEILKYAFSSARMAILLLLENSFQTFTKSDVYKRMEKEIGCSGLYTSEGRESAVFLLKKHLKKMPQSTEGPSLRRTLLIKHMVQEFCFVMLDIDMQSLDDKKSSGFSNWMSRRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU92</accession>
    <name>A0AAD5TU92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001334">
        <property type="protein sequence ID" value="KAJ3204148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU92"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041999261" evidence="1">
        <location>
            <begin position="18"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="214" mass="23604" checksum="9F800F8E0D41260F" modified="2024-05-29" version="1">MMKSTLFLSSIVAIASSEFIFEEMNECIKGCVSSTLSKVENAVVEPCQEKVIVHYHNCVTNLVCPDVEKFLPTNACPNYNAVVSNLKSDAKSIQSSTVITTLALAGIDQISSIIPSDTTSLTPTNPPLVINNESTDFFTPWGNVPRNVITNCSIECIVKTSEKFSTFIEPCRDELIQEFVNCEKSNNCPDIKEIVPYEVCKNSLILNPDFKFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUQ8</accession>
    <name>A0AAD5TUQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001938">
        <property type="protein sequence ID" value="KAJ3200269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUQ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="91" mass="10794" checksum="8BC3F4787F96E455" modified="2024-05-29" version="1" fragment="single">YQCDHFFSTLIFITVRRFENIIDLKKNVIDDQISKAGKEVALKFSRLENVNELVIKEIKKKSIENKLEFERSDKLKKLKKNKKKTLSIVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUS1</accession>
    <name>A0AAD5TUS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001077">
        <property type="protein sequence ID" value="KAJ3207138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUS1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3207138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="84" mass="9774" checksum="DADDDCF2CCECCC4E" modified="2024-05-29" version="1">MPNQYGYPTKQDLILNPNSNKRTTQELKPTKNSILNSLKKVSPNNDYTEQNLKTWLKSKTVRHETYHILIIVGELVGFLENARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVK4</accession>
    <name>A0AAD5TVK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Iron-sulfur cluster biogenesis chaperone, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HSP70_1</name>
        <name evidence="7" type="ORF">HK099_000276</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Assisted by the DnaJ-like co-chaperone jac1 and the nucleotide exchange factor mge1, it mediates ATP-dependent Fe-S cluster transfer from the scaffold proteins isu1/isu2 to grx5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001059">
        <property type="protein sequence ID" value="KAJ3207362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVK4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11733">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000014">
        <property type="entry name" value="Chaperone protein DnaK HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000020">
        <property type="entry name" value="Chaperone protein HscA homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003520">
        <property type="entry name" value="PRK05183.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="627"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="645"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00059314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00070638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3207362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="656" mass="71668" checksum="0E671EF9A2399CF1" modified="2024-05-29" version="1">MFRLSSPLKQTRFIKNVRNASDKVQGQVIGIDLGTTNSCVAVMDGKTPRVIENSEGGRTTPSIVAFSKDGELIVGTPAKRQAVVNPDNTLFATKRLIGRTFNDEHVQKDMKTVSYKIVKHSNGDAWVEARGKKYSPAQIGAFVLGKMKETAEGFLGKAVQNAVVTVPAYFNDAQRQATKDAGQIAGLNVLRVINEPTAAALAYGLDKEGDKIVAVYDLGGGTFDISILEIQKGVFEVKSTNGNTHLGGEDFDNLMVNYIVKEFKKESGLDISKDRMALQRIREGAEKAKIELSSTLQTEINLPYITADATGPKHINLKLTRNQFETLVKDLVDQTIQPCQKAIKDAGVTTNDINEVILVGGMSRMPKVQETVKSLFKRDPSRGVNPDEAVAIGAAIQGGVLSGEVTSILLLDVTPLSLGIETLGGVFTTLISRNTTIPTKKSQVFSTAADGQTQVEIRVFQGERQLVKDNKLLGQFNLVGIPPAPRGVPQIEVTFDIDADGIVNVSAKDKATNKDQSMTIAASSGLSDKEIENMINEAEKHQEEDNLRKQNIEAKNDAENIISSTEKSMSDFKDQLDKEEENKIREKIAELRKVISNEDSSAEEIKTKCGELQQDSLKLFEMVYKKKQNDNSSGDKSNDGDTVDAEVKDDKKDDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVL7</accession>
    <name>A0AAD5TVL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001671">
        <property type="protein sequence ID" value="KAJ3201797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVL7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="66" mass="7492" checksum="1307167F254CE8FE" modified="2024-05-29" version="1" fragment="single">TLEEVLEKHGPQLLKSSQESQSFERHRDFESPNKKKRVNAPKSLLNPTLPVKEPLGCVFESESDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW13</accession>
    <name>A0AAD5TW13_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid scramblase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001016</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phospholipid scramblase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001262">
        <property type="protein sequence ID" value="KAJ3204822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW13"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017128">
        <property type="term" value="F:phospholipid scramblase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005552">
        <property type="entry name" value="Scramblase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248:SF9">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03803">
        <property type="entry name" value="Scramblase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="244"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3204822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="331" mass="36667" checksum="48D1B41A40D51620" modified="2024-05-29" version="1">MLKFAYTPIRRISTNSRITASLRAQKLKKKVNSSNIENLKKINQISEGTENNKLSTEVIETTLVQNPTATVNRNIDGVDIGFIAEEDGKLSQSVVRQVMRTRRQFKATVLDANGNVVLKILRPVKWLINSRITILNELDEEIGEVTQVWHPWRRKYDLFIKKKQFAEVDGDFLTWDFSVKNEDNKQISLINRDFMGFIKDQRAVILACAIDVDIDYFSRHSSHTTPIIPFGASVPMGGGSGEVAPTPPVDGTGVGTGGFPSAGSNSTSTPGAGNKWGDEEFTPDQGFTADEGFTPDEKSTEDFMSNASENSEGFFSAIGDIIKKISDFFND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWG1</accession>
    <name>A0AAD5TWG1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001559">
        <property type="protein sequence ID" value="KAJ3202520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWG1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="500" mass="56841" checksum="7329BD90476941A5" modified="2024-05-29" version="1">MVSEPTLLSSTVHLTSIIPVSENSKKNPSTRSDKTNSNYKRKSFNETFHFGSKKNNQTSLPPVPHLDKDTIEQYSKSSHARSFSENEILNHSSGSEISSLTFFSHYPSLRKKSASENFHNFHNPFKEEVNLPPVPLAVKSVSSNSSSQNTLVDNEMYNMDKSCFSSPSSSSSSSIAEVGNLHFFSPLSNFNAESEEKVFNFENLKLNSPIFEKILPGKNKTKKRNILFKEKFDSNFIDFKIDFGSENLNLDFNFTLSDLKLNSGIQSDLKSNSGIQSDLKLNSGIQSKEDSVRNPIEINKNLVDCQVSESEIKKAKEITSTNQNVPEIKLDKTSDRSAIEDFILDYSEPYPCLVSPIRSPNTPDSPKYENMMECSLNGVNINQQSPSRTPTRQIEIQNASHSPPIFLPTPPSSRQRTNSSKSRNGVFGFLKRRSFIFSSSSIFHNNNKNENFENWDLDKEEVFEKRIGKMMNFEEMIRNEETTKVNNYNYHKFFLFFTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWG4</accession>
    <name>A0AAD5TWG4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Homing endonuclease LAGLIDADG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000714">
        <property type="protein sequence ID" value="KAJ3213411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWG4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.28.10">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027434">
        <property type="entry name" value="Homing_endonucl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003647">
        <property type="entry name" value="Intron_nuc_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004860">
        <property type="entry name" value="LAGLIDADG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051289">
        <property type="entry name" value="LAGLIDADG_Endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181">
        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36181:SF2">
        <property type="entry name" value="INTRON-ENCODED ENDONUCLEASE AI3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00961">
        <property type="entry name" value="LAGLIDADG_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00497">
        <property type="entry name" value="IENR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55608">
        <property type="entry name" value="Homing endonucleases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Homing endonuclease LAGLIDADG" evidence="1">
        <location>
            <begin position="115"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="360" mass="41530" checksum="D6E3B50B753B3507" modified="2024-05-29" version="1">MHINNIEALKIIKSLLNVGNVTVEENRNCCSFVVQDFTEIKDVICPIFLQYPLLTSKNLDFKDFYKAIIIKNKNNLSLTDKEKIILLKNGMNSKRKIFTSFSINSQINVSPEWFIGFFEGEGTFGIKTGSSLYFQVAQKNTSIENLNAIITFLTNLKATQLKKNSQILPLNVVSIINKKTDVISLVVSSVDAIYYYLLPLLDTSKMYTNKVIDFKLWRMALILKIYGYYYLSEGKTLFLDISDILNKRYNPSAQKNINLRIEEIFNRYQLILLKNPPFNVENCISHVDNVRDYRLKIKSDIQKTIYIYENGKLIKGSPFSSFSNAHKALGLKSTSNTCNRYLDTNRLYKSKFIFTSKHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWI5</accession>
    <name>A0AAD5TWI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007812</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CATSPERD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000798">
        <property type="protein sequence ID" value="KAJ3212046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036128">
        <property type="term" value="C:CatSper complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030317">
        <property type="term" value="P:flagellated sperm motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028751">
        <property type="entry name" value="CATSPERD/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33722">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33722:SF4">
        <property type="entry name" value="CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT EPSILON-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="608"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="723"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="799"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1083"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1119"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2083"/>
            <end position="2138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="723"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="744"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="763"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="806"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="820"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="845"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="917"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="960"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1002"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1083"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1124"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2104"/>
            <end position="2118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2123"/>
            <end position="2138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="2138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3212046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2138" mass="244128" checksum="FAC0E35890006727" modified="2024-05-29" version="1" fragment="single">ESQIITKSFQEVGELPNIFSIEEKEFLISSIEYNKDKMYWNIQFSTTISGELPIIIDSSKQPIGNCLIQKSKFILNIKKLSLNFLNFLKTKSTNPVISKETDFEIIQDACFNNLIFAKFSDGVVLVSQNNLTKPETTSFLDFNQIFNQSNTNIIQTTMTSNTTCFLTESGIFCNNYQEDDNYFFPSGISTSNNLNNIRSLDFCSTELESTILNEVFITWSSETSETEIFDKVFLSFNSRLNFTSLNVPLGIGGIISDIVIQPTFNNICILYQLKGMFQILLYNFGSNSFSNGFIFSEKLKSLVSLGNIVMPKLKVVAKRGGELLIWGDGLVYRNNLLTNEKEGLEKTEYLKKVITTVDGDIATLTSLNRVFFGKSGLLELIEITAGISIEAKVADILFDSFKRLLIYTVNNLGSNFNVRYISINNEIQNLMPPLFTTPLTCGFEDWTSDLKSTYTLDMNENLNFSSKLIPKINSSNKISVSYTNQTITSFKTTFKEEPIWSLTKNGIVLKEMVSNTSTHIKRHIDGRVDVVLRPHAANIACDSIAKRSTVRVGCPLTRKIKFRNSVPTTGVTNLILKSYYYYTDFFTKQVGIVDKQVKRRKVSTFSALDGEDSQQHQNDVQNHNRFNSSESGRRSERFSSSLSDNGKRLEEEKKNNDEIVVLSFEEIIKQKRLKGAVNEKASAENVGLKPPINNSGEVVSNVDTKAITISETKIIATLDTPKDVKKEKDSSLEQNSNRDDFSKNSKNMENIRNPNLIPLGEPNYKKDEKKNAEKSKNVAQSTFRRVEPESMEVIYDFDSDIEEDGNDQKNRKGTQDEKTLNSNHDNSNSVSMGQHEKNFTYSDTNDGRITSEHSNKVDKNSKVSSKYETDMREGDSNRIGKQVRKEDLRSRDAASDVKYRNLHDISAQRKSSSPSFRRAEYSEKRDTTSDRGRRRSPSSSYRTQTDGSKVDKNFSSSKVFNERQRNEKEPDLGGSKGTNNLIQPMNIAADEKNITLGRKRDRSFDTSDRNSKSRIDDRPPRSDIKATEKEYSSRLRRISDHYEPETVKFRKDHYEPQPRGRNDYYEVPHTKSKHDYYEAKNKLEHHESRSKLDHYETPSAKSNYDKTSYNLSQSATKFYDEGSSRNSVYTADSVNSTPRTGSQNYAKSIPLKSNKNEYAPSQKTAIRDHERHHVASLSSGNLINIKHSNHIEPEKNTPERVVENNETHGLTLTEVYAGFPLEKAWNILVQSSGEQLIIKELYKNLIFEAMAQKNSKFVDRFFTAYKSHHSASVSSVDFVQVLSFYINIGDEITLENELKTLFSQSFKFTGLEWSTVWWSGEPLLKSSKIILLLLNAMEKQYLSMKKENLLEFSLMDSITLDLILSEAVSCGLMNQALNFFFTVLKFHKFSQSSKHCEPFFSSRVLEDFLSAQIKSENFTGVYNVFESLLELNINFNNKNLLELFDILLKSGKEILAVDVYKFIAKVNALTYHDAPKLLDYIKLLLKNSRVNDAIEVLKKMQTLKLPIRGMANLRELIQLALEQDCIERCLQIITAMIAPSDGRQLLHLNFLVCSDIINACVNKKLYPHAFWYLKYMKSKDIQRSASLYQLMFQTLAETEKITVSDILDLYRDAIYSGYHLTSKDCGYLLQTLSVGDVKTAKEILKEISSTTVSLSCIPTLVMLNLVSNSEEGLEKLLNNYILLGYVSLYHLNTMDGKMDETLLENAFRYICRVKKNYDLAEKLTLDLRKHKEFSPSDSFCNSVFLLLDEDQASLDDPLHFGIKLLYLQNEFNFNQSLISDIIAGKFDLSGCQSFLQLKLTFVRFLEIVNYKLMRESNASKLPESLEVILPQQFAKFGESVSTKVADVKIVDMFKTFLTKDLKPTIKIYKDVLVNGKYAVYIEKYHLKQWLFDIKNIPNFLHCLSVNDISVEKGTLINDLKEEKLISKKNIQTTTHPKIINSVLKSKNETKIDTPKATSVLEKSSLPPPTTTTSPHLIQNKYRPDKDNTTGFIEYFDAVSTSSSGTVNNKNKEVFERVLREVKRVMYELGLHNLPKDQFKEFSRIYTKGMMSHTDAMLIYSKESLPNNNDLRKICSEYINSERKKSTKINNNDHKSSTTGTNSTKVDHMLIHKKEDRHNAGRYHSTTNNSSYPTSGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX11</accession>
    <name>A0AAD5TX11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001019">
        <property type="protein sequence ID" value="KAJ3207990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX11"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="143" mass="16242" checksum="BFB0194B27864921" modified="2024-05-29" version="1" fragment="single">FLSDPSKNDALFFHPVESAGPDLVFFICNGDDKLVPVFVQLKLSRDVNRKAALSTIQPNLFYTDKNGKILEKYQQEFADCMKSLEFYGRCIGLVICYPKTFRNEVAGIVEIGGLKCYKRVIDKTNVNDIFGERHLNLLAQIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXB4</accession>
    <name>A0AAD5TXB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007229</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000685">
        <property type="protein sequence ID" value="KAJ3213690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXB4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042262313" description="Peptidase S1 domain-containing protein" evidence="4">
        <location>
            <begin position="16"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="32"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3213690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="278" mass="29089" checksum="7291E59C3D6952BF" modified="2024-05-29" version="1">MKFLTLSAILIAVQSAPSFEDAEIAPWFKPSIVGGEPVANQSVYPWVASISISGSSHSCGGTLIAKNLLLTAGHCSAGSASSRKVTVWRYDISKTAASEQAVQYSVEKIITHPSYTGSPVPLNDVSVWVLKQTSNPANRVVQTVNYAKTADHPLFPGKVRAIGWGTTRQGGGGSLATKLRQVDINLISNAECKKSYESQYPNGVPDSTVCAAEAEGGKDTCQGDSGGPLFQTNEAGEVVVSGVTSWGIGCADKGNPGVYARVGSFSSWIDAQVAQYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXZ6</accession>
    <name>A0AAD5TXZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD repeat-containing protein 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">WDR12</name>
        <name evidence="7" type="ORF">HK099_006795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000608">
        <property type="protein sequence ID" value="KAJ3214583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXZ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855:SF11">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855">
        <property type="entry name" value="WD40 REPEAT PROTEIN 12, 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NLE" evidence="6">
        <location>
            <begin position="13"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="258"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="346"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3214583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="425" mass="47895" checksum="281B35A626DF63AB" modified="2024-05-29" version="1">MTSSIATDPITSVQCIFVTKNLLYSSLIPTNPILIPTKLRRFGLSEIINHVLNLEKKIPFDFIINDNVLTTSLQTYLKKYEISNENVLTLEFVESLTEPKLEKAMKSNDWIKCIKANNEFIATGSFDHRTRIYNHSGDLLHNIEFESVVQSLCWLKDESGIASSVILNGNQSGIVECWKVKPDEMEKELVFFCQDAQGAIECLDVNFDGTLFASASFDSSIHIYSTDKDDNTLDSTLDQSKRRKTGKIVKKKIASGTLKGHHASVSSLNFSKDQHSNTLFSVGWDHTVREWDVNEESNKNTMNCENVILNISQSPKTGLLATGHTDNLVRLWDPRVKEGLVVKLKLKSHSGWSSCVSWVNAYNLVSGGYDGFLKVWDIRSTSPIYSIKTFDNDSDPKKIFGLDILDQRLYSGGEEGLLRTYFCTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY69</accession>
    <name>A0AAD5TY69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006451</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000557">
        <property type="protein sequence ID" value="KAJ3215237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY69"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="521" mass="58280" checksum="FACD7B99AF5500E6" modified="2024-05-29" version="1">MKDFGLTFGIKFIDTNDTLISTVRAPDIKGNITGYFLAGCAIGALCVSVLADILGRKRSILVGAILFSAAGLGQALSPPVIEVFYTARFISGIGIGILSMVVPLYICETAPTAVRGRMIAVQQLMITIGIFFAAVINVCIRAMQNGSELEWRLSLGMQVIPGVVLTVITFFVPYSPRWLEDHGRHEESISTLAVIRSSKVTSPAIIAEYTEIKEGVLYERSVGNASFKELLRPGILNRVLIGLALQFFQQWTGTFPGMYLIERIGRRKLLIYGGYIMGFCQFLICFSSMFAKNQENIFSYMAIIFVYIFILAFSSTWGPTVWVYQSEIFPQRIRAKGTGITTFMNWTQNAVIAKISPLIINSIDSYTFLIFGGTGVLMACFCTFLIPETMGRSLEEMDGLFGRSTPHDIALKPFNVERNNATVTNNDTSIQPDLNQDYEDIAGLQKAVEHEEIQNFGKKGILRKSKINKSHQKNFQDTDKMLNKMSKLNDEGNFFKRKVKNKKRSDFLESRTKKKVKLSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYK1</accession>
    <name>A0AAD5TYK1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000514">
        <property type="protein sequence ID" value="KAJ3215881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYK1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="63499" checksum="890729515FA97C6D" modified="2024-05-29" version="1">MIFEQYTNSLLLDLYSFLSEDDFLDSGAKFLLRELLNSLLKNSPSELNTKVLLKENLLKINAEDQQIFFIYLQKTKNLLKTLKVKRKDKERLSKFIKNLEELEVNMFSKPSYLTLDPAAKTNLPNKDLRPSTINKFPNEILNLIFSNLKTLSHSSNQMLLNLALVKKRWSTVALPLIYNKLYTNHDNLVTLHKLVKGLNLNKEYLEKDKFWFKPNIFSIEFFSKFKNTSQQYKAFNKELILEIIKFSKNLRQLAFVVNEKERVEFTLQDLSFIFKHCSNLVSLDISGIKINHGEEEETITAVKNGFSKLKTVRVFGLNEGELVYIFKLFEDNLRNLELEEVTPELSKVLVGKLKNLTVLNLTKSDAPFHMEAVNNLFKSCPNLKSFYTFRLTNVILNALVDNHIRLKKIQGWLDGRGEDDLFHVDFETVSRFFNNSNLTEINFGLIKFNLFSGKNNLKLLSENLSNLNQLSIFANYNQNISPECLFKCVASTDFKSFLSDFKNFLVNVRKLKTFLFKFEEEIEGNEDELKEIKKLLDEFKIKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYS7</accession>
    <name>A0AAD5TYS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MEP5_4</name>
        <name evidence="13" type="ORF">HK099_006499</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000565">
        <property type="protein sequence ID" value="KAJ3215132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYS7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00999">
        <property type="entry name" value="FUNGALYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041769984" description="Extracellular metalloproteinase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3215132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="754" mass="81844" checksum="66B8D52E48917083" modified="2024-05-29" version="1">MKSTLFASVIALATSAASVPAGESNSLNSNTGNLLGTTFPKYFQPASTVEEVVPLLEKRDGLAKTLEENQQLALDHVSQLTGTPKSEIVLTSSVESSGGFTTFHFGRILEEKLVDNVAANVNVDSLGNIVSVGQSWTTNKETVKNETKITANDAVKAVTSALGLPFDENAVVENKVDGAQFFSGFDEKIVGDVKVSEKYYRTSNTLEKCYNVVLKLKDNHYTVFVGQESGKILGANNWVTSDSFINQNAKQKRSTLTKRADYKYNAVVFPQADLSEGRSITTNPADKTASRLGWHNTGAGDVGTTVGNNVQAQEFQDQNNPRRATKADFNFDYPIDEKKEAKTYWEAGLVNTFYVTNAIHDISYHYGFDEKSGNFQKDNFQNGGKGEDEIIANAQSSVLVNGQNTNNANFGTPPDGEHGEMNMYLFDVTTPGRDGDLDNNVIAHEIFHGVSNRLTGGPANVDCLSTTEAGGMGEGWSDVNAFFLTTKTSHTRNTDRSTGSYIINNAAGIRSKIYSTDMKKNSYTLEDVKKNFEVHDIGEIWATMLFEVMWNMIDKNGFTENLISDAKSGKGNTDFYQILLNGLKLQPCSPTFLTARDSIILADKNLGSKYSCEIWAAFAKRGLGFGATKDYKNNFDVPPSCTGKAPTSTPTEAVTPTLAATTTTEAILTTPPASKTAVTTTVAKTTTTLSKATTQKPQPTTSTCVHDKCLTGGFLQASCDSCVAKICAKDPYCCTTGWNKRCKRAVQTVCNQKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYY8</accession>
    <name>A0AAD5TYY8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEATR5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000440">
        <property type="protein sequence ID" value="KAJ3217178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040108">
        <property type="entry name" value="Laa1/Sip1/HEATR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046837">
        <property type="entry name" value="Laa1/Sip1/HEATR5-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057981">
        <property type="entry name" value="TPR_LAA1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663:SF0">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21663">
        <property type="entry name" value="HYPOTHETICAL HEAT DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20210">
        <property type="entry name" value="Laa1_Sip1_HTR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25808">
        <property type="entry name" value="TPR_LAA1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="197"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="425"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1786"/>
            <end position="1806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="160"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1786"/>
            <end position="1799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3217178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2612" mass="287672" checksum="84F35896911C57DB" modified="2024-05-29" version="1">MSLRAEAIFDCESDDPQQELSFKKGDIITDVKPGVDDGWFMGKLGYKYGLFPGNYVKFFNDEFQTTTKAAPISHQTPESYNHARSISAPSQNLISSESTSAKVYRPMNLNKVDARKAIQERGNQIVRETIEKRSVSNPVGKFNMNSALNEINYDNSNPTQSLNNKFLQNQNSNNSHLLSRNEMKQNENMEKSYGMNATSTAVKKPTVLHSNKNSDSPEIPNRNVNKLSSSSLQKFESNSSIEQYTNTPPKIGKKPPILVSNQSYQAPALPSRSFGVPVNQFNESSTSSIDSMNAKKQVDVENDSTELNNADQCIPASSNNSLIAKKKPPPPPPSKSATLSNYTPGFKGSSPSSSTAEFLVDSGRPLKPSELKGQNMAKQTIPWLSSATASKNIIHNQQESANEGQSERPLRPSELKGKSAFNNLQEKVSADISPPRPSFTTKSPMQTMNSNSTIFDQTPRLPFRTKEISKDDHELSINKPEKKDIPPPLPVRPNDGDLATIPPRPSQHNGSNLKKIISIDTKRRYEKLFEQLDDKFTGNLDGTTVRSCWIKSGIDNRGLGNICSSEMETFVFNVEEKITAADADKKDLVLFQWLSALENFITLAEKEELMKQQQQITSTIINFINTTSPKPNRPIRNLMSRCLCSLYTKLKDDTRTLFDTLQTLQKILALKKVDDPQIKIAAISIIGSLELAHGSKVLSLSAESISSITKHFKNAKENELSLKIESLIALTKTVKGAGRGANEATIKDLMKIAKAGFLDKVLLTRVSSLELYEAIYTNTSQPPPLKDEYEGIVSSISKTLENSNQQVRQAAASALSSIIILSQQPPPTLKNAKKSNQPVQKTILSEAEMIGLLSSSILKAINKEVKVGIFEVYLSLIRNIGINFLESNYVTISNNLIELASNQKMCQNWNDVVMMREATGIVLRTIGKTISEGGQVTALQELNRNWLKKVAVESTCPNKYALVIVLNEMSALLIDVGSAAASLQDSLYESLVALLSHAAESVNIALCWTLRCFCFSLPTNLPKLLFKLIPMMQKDASVLSGEKQDQLKKFLFLGSAIASLITVVPHKTFYVSFENSAKVFGLATQLLKSSQSEKAKDFKVMQAQGIALNLRIFFKILVQTAWTLIASLMTMGPNFEKMLRKLLKSHNQYYIIRRLRTESEILYHLSMREAALGALHCFLHYNSKDLLTNDVAKRLLVCLNNLATYLTAPSSIQQVPVGLAANSVQRSQVTFLDRENAIRFRLFRCYSYIPTNLYETTHAILLKATIETFALDPEKTVDRGALANQVGDKPNGNFEFWGQTSLANGFKIDVAKSSGAECRGIGMVLSKDIQNKVIEELIEPYTLNALENDPYAIYLQNKSDQSALSVNSKLNTSADLYEISYIRPLPKPISICVVDSAIELFCLLFPLQSASVQEVTLENFIRLSKSAKATVSRRNTFQVNVLTAIIGTLCYIMTKHGSLASGRVHVAIRDLVEDSLISTNSLLRLVASEVLGRLSRVVGTTIFVNEIMQNLIDIVVNNREPEARAGASLAIGCINSYVGGMAAGAHLKTIVGILHSLASDPHPLVHKWALFSLWLTIDSAGLLYGPLVNSTLTVVAKLFMSESHETTSPLANLPTAESNADVYPCLGKILYALLGVVGPELSSSAKVRDLCTSLYEELKNDGDAFVMVEAIKCIQHFILFSPKHMNINTLVPFLQNQLSSSVEHSYLKRKSSVTCLYQLVQRDAGKVQSAGVQLEEQLFSLLDVESDQQVQLEIKDILMGLLKHMAPQCPSRWLELCKGILSKAGSSGTVAPTQPQEPSVVSAAEEDEENYHQDVSSVPKKKTDEKSLVVILVPRWRTQVFALTCLLHLLPTIKNTDIKEHFNLKLARKFREANENCDFLVFKLGDLVRIAFNAATANVLELNMAGSYLLNSILHNYAASADPDVEGNALLEQYQAQISAALTPAFTSNACSVEVKSLACQVAAAYVSSGINNDLNALGRVLKSLSTMLEQYSGDNDSDISPHGQLLLRLSILASWADIQNASQKLAIAKEVVEPFLHILAPQWVSVLRDYAKVRSDIETNANNITSGNPNGNTTSLDMYSSATRELTFPYYKKWWPSILQAVSSLIETHESLLLPLIGIDENKEPSKSFKMVYGLCTEFLSTAEFSETSLDTIGLTIVQNSRKKSLQIILSSFKPFLSARIAGPKFLGKTEDVPVQLQIVEIIHQIVKEYGESYFMDEGVDVALSIGGSMDLLNSPVGDFGSSVPVDSKIYSVAKLLYNIFILHVPALSINPTALFSAIKPVTVESASLLVFSSNVITDLLAFPNASPFFVNSLAPVVLYLFVAILGTEKLAEEVSPKLLIPIRVVLEKISNSTSEFDKGSLSNVVQGFAFSLLDTIFPENEFSGDISSSELALLKNCMLSLVLVHTTCPDFAYNETILTRLTKYLQKAITSNSVGLSVTALQCVKALTAVHLKNRESSNLIASEIIRNIGPTIFGTIFTLSKHREVEKNLILLECSKVSVDWCLNAKEISTDATFTVSAMSILTPLLINMLVETSSRNADEIHNFALESLIKFLSNEGNTFKIIVSHLDTSAKVKFEKCFKAYVGGGSNNDENVTKNESSVQSIQLKSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ03</accession>
    <name>A0AAD5TZ03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000449">
        <property type="protein sequence ID" value="KAJ3216993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ03"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="424" mass="50602" checksum="E97B66249A3FD5B4" modified="2024-05-29" version="1">MSSSFVEDHEKKKKLNNLKNLANYMEKKFFPDNTIDKEPLVTLLEENVHVSSTSSAEKLQQNHRTLTTSPLFDNGFPSYVEESFLVKNENDLKFSFEDSDSVVNWYQEMEEQIFKKNEFENLSSSEHKINNGNHSIIDNDAYWIDRFIAAEENWKENGILSGQNSSVDTANFEIDYSLLLDPPREADDHFRLLFNDFPSKVENDKKPLIDELKEDNLLVFFKNHGDENVVNHRNRAQVFRIIEPSDLGQNQKFSIYWDGESRKYYKLECSCNILIYRTKFGRYKLDLRYYRGLERETRFGDEILNVFLNEIDVEYNYKIRNAINYVKLSRKVRDSDTANCSKKRKNNLADSEIDKKKFFLLILQFPIRLTEDMFQERLKKAQMIEEKYYNERKDIDVQYLEKRNIEYVPLTLEEQTIKFDHYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ18</accession>
    <name>A0AAD5TZ18_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD repeat-containing protein 89</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">WDR89</name>
        <name evidence="4" type="ORF">HK099_005291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000403">
        <property type="protein sequence ID" value="KAJ3217932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ18"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039328">
        <property type="entry name" value="WDR89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="167"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="315"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="349" mass="39129" checksum="B3DEE934FDD7554D" modified="2024-05-29" version="1">MAFQPFKLKKQTPKDARNYCLNVLPNSTESILAIPNSSNKIQILNSTNLNLISELNNEIDLNNVDINFQNSLKKKKRQLKEVLTDCTFGGTENLFYTCLNDVEGTVNIWDLRSGGKVSVFKGYVPLLSIAVSCAGDLLAAGTELQEEDAKVLFWDLRNTSTKLSEFSEAHSDDITQVKFHPNFKNWLTTGSTDGTLSIYNIEKTFDEDEAIFQTIRDNSINKLGFFGPSNEYIFSLTHIETLSIFRVEDAETIVSFGDVRNTTKLNDSSTAIDYLIDCQYISSLMRLFVFYGTNDGNLGILNVDLDSLDLVHKLKGGHNGLVRGAHWRRDGRSLVSCSEDGVVSLWDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZC1</accession>
    <name>A0AAD5TZC1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000669">
        <property type="protein sequence ID" value="KAJ3213870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZC1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042058370" description="SCP domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="160"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="312" mass="33852" checksum="C2C034C9E8C37028" modified="2024-05-29" version="1">MFTLLKFGTLSFILTLVQGNVTPLEESVAGLTFESILPSDLGKGAAEAGWSLKCDPNHGLAGTVIKCSYTTAYVNANNWVGFFFDRQTSTSVFTKLPSNNGVVHFTTDNYIPGSYSFKLVDGGSRYVKVEAEYTVDKSTPTETLPTSTVVVTPTSTSTPVPPNEWLFAFNTNRNKFGSPDLSWSSYLETNAKSRSNAIAANNCNLGTPYNSNGAGLTIYKGYGNTTPTDIINYFFTGSQHYNNGYCYNNVNACQVFTQAAWRSSQYVGCASTKCGNTGYFVTTCLYLRPGNCNGVNYQSNNSPCGPFQPPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZV7</accession>
    <name>A0AAD5TZV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000377">
        <property type="protein sequence ID" value="KAJ3218520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZV7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF95">
        <property type="entry name" value="F-BOX PROTEIN YLR352W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="35385" checksum="49BB51E76B074A80" modified="2024-05-29" version="1">MIFYLRKHLTEVNLSQTNFDDLNFFGLLKNCTNLKHINISDNHKLSDLFSKLNENDFNTIKGNIKVLSLNLSYCSNLSSNSLHNFEKIFMKLEQLNLEGNSSMNYNSLNVISNLMELKSINITGLNYEENGDIHFVSSKIQDFIVCLSKVEQFNLKFCPKFNGDCLSLVSACWNELTFLDITCNSQARISHFEDLIVGCSKLKTLLIGSCPGVSDEVVYKLVKNLKYLETLDISKNLSITDKSVKLISKLGASLKELSLSKCQNINGQSLKFLVFRKCGVSLKFLDISGLPNITNETITQLYTLSPNITLVSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZW0</accession>
    <name>A0AAD5TZW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000562">
        <property type="protein sequence ID" value="KAJ3215190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZW0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="140" mass="16075" checksum="291EFAC2D33279A4" modified="2024-05-29" version="1">MYSYQVFTQIQKSSSDETVVILMPINDKSLIISQERKFSIVTIITSALTFFTSLLTFYWFLFGPGPFTPWGFLQQRLGLVSKIALERKKQKGGKLIDQDLKLFLKIKNLRVNKKDTRVKKFGNIPLGLVELEEVTADKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZW1</accession>
    <name>A0AAD5TZW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007576</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000747">
        <property type="protein sequence ID" value="KAJ3213090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZW1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="80" mass="8943" checksum="1504FF024A413AE5" modified="2024-05-29" version="1" fragment="single">MSMKTEITKHNVTTEVTSELKVDPYIPKHLPNNFKNIEDGLTAIEMDQILSLGQGPAYTVSFECAHHAFEELAITDPELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0C3</accession>
    <name>A0AAD5U0C3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000670">
        <property type="protein sequence ID" value="KAJ3213853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0C3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="211" mass="23949" checksum="E6779895970253CC" modified="2024-05-29" version="1">MNETEYLLALQDWNQKTSLRWPLNNVAPSILAILILIQLKPTLNRNLLLVSAIAKIETGIVYLIFTNLSIFKGLKGEVYGVWGYLMVGLCTPGWLISETSIVLSNGLRCFYICGDQKYKKVYKISAGILIVCEIFWRIYGATFSQISDDVNKPNAVIAMINTFTWGTNAVADLIICIRILWFTVYQLKCSSVQKSTKTIYKVILHVKTFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0I3</accession>
    <name>A0AAD5U0I3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000327">
        <property type="protein sequence ID" value="KAJ3219799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0I3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="31934" checksum="59BF287E1AEB1985" modified="2024-05-29" version="1">MSSTNSSFATIFSTTTLSKSSFNSSTASRTSSLSSLQVTTTPLSSNDSFSGNSTNFNISTSISSTTSIIPVILTPTPVNSGNEQNSLELKYLNIPLLAWVIIGIVALLLIVAVIYFIFFFDKNKLRENKKKKILRKKNVGVSNAHTLESIQPHFIENYDNHVDEAIMNVVKARQQELDRLNEIERKKKIEEEKRKAALNKVNVGSNGQFKKTKVFNKEEMTKKLAKRPLNNHVTDLEKQTKINKFRKTLLNEAPNLKSTTTLNETPIVKTDEENNNMNPIPEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0I4</accession>
    <name>A0AAD5U0I4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[histone H3]-trimethyl-L-lysine(9) demethylase</fullName>
            <ecNumber evidence="2">1.14.11.66</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_005903</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 2-oxoglutarate + 2 O2 = N(6)-methyl-L-lysyl(9)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:60200"/>
            <dbReference type="Rhea" id="RHEA-COMP:15538"/>
            <dbReference type="Rhea" id="RHEA-COMP:15542"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.66"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the JHDM3 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.66" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000482">
        <property type="protein sequence ID" value="KAJ3216367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0I4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051864">
        <property type="term" value="F:histone H3K36 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140684">
        <property type="term" value="F:histone H3K9me2/H3K9me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF7">
        <property type="entry name" value="[HISTONE H3]-TRIMETHYL-L-LYSINE(9) DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjN" evidence="8">
        <location>
            <begin position="119"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="9">
        <location>
            <begin position="385"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="10">
        <location>
            <begin position="618"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3216367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1059" mass="120646" checksum="A81BD359272841E2" modified="2024-05-29" version="1">MLVNEERISHPSYSPTSVSKINDTSKETENLITFATNYQVNDTLVTTSNHNIPHLSSENDAIISRESVTDGELNSLENATSTVENYAFKEDIKPIVKSIEQELETLFPHHYSNSDGTGIPVFTPTWKQFRNFNKLMKRIEIFGKEAGLAKVIPPKEWNLGLVNQTDYLKDVIIKKPITQTFEGGRLPNGAYRQTNIENRRNYTVNSWFEFCNQNPPPQFDELGKVKKFEKLVNNNVLNKDEIEVKEEKKKFKKVDDAQLENNLHYNVNLIDLHENTEKKFQPAATEEVKNDEVNAESSLTILTKKSTFINENLTPVVTEPVDVAKQLEPKKRILKSTVLNFDPYKTGEGFDEKYCEELERYYWKYIIFKSASYGADLMGSLFENSKSGGKWNLNRLDNLLNKIEAALPGVNVPYLYFGSWKSTFAWHVEDMDLYSINYIHFGAPKQWYVVSPKDAAKFERYSHSVFSSESQECSQFLRHKAFVISPKLLAKNDIFVHKLIHRAGEFMITYPKGYHQGYNLGFNCAESVNFALESWVDYGMKALYCKCISDSVKIDVKTLFSDLSKLTKLNIPEKREGWEGRIIPKSDNLAAVNTTSVLKMRGKNAAQLKKDTSFKPNGPRCAFCIDLVGELYPTDKENFVGHEICAKGIPELTFLEDEKKIVGFENIPKSRWKLLKCDVCKNERSLSYSKEGCCIQCIKGKCVKAYHVTCAKNTGLNFSYNAETNIAEIFCPTHNPETLEEKKSRKELALHNFQLLNFVEGKLVIVKVGSSGYEGEILNVDEAEKTCEILYTDDKCIEIVPWQNIRLKSEDMLKDRACVSNAPAKKKVIKAVVPKKKVKKEKKVSNDKSSAINNNSNIPASPQIPFYPATQSEPLKYNSVTKEGKNLVPNSYTASYSQLFNPGNIYYNHFHNFELMKASIAQSKKFSFTPHQWNNNISVTQSGPFQPLPTSENFNTNTNNNFTYFPCQQPTQPLCEGNSLSSTLTYNTLLPPKKRKVGSAAEPATEVNSKKIKTSIIDEVKSSKPLVKNYFYSDEKFHFSNEESDKTINLNNDVQQRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U101</accession>
    <name>A0AAD5U101_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TBC1 domain member 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TBC1D9</name>
        <name evidence="5" type="ORF">HK099_007669</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000764">
        <property type="protein sequence ID" value="KAJ3212763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000002">
        <property type="entry name" value="TBC1 domain family member 9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="654"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="1128"/>
            <end position="1163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3212763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1358" mass="154789" checksum="8F021B92AA0D71C2" modified="2024-05-29" version="1">MVFVKPIDAELLSTGMINWLDKAGNQYFSLQQKKQGNAFFGNLLQNLSLQATIYGPNKKPINDFEFRIILKTQNGKKLFIVAVDQSFETIHKELDTKSYNQIDKLLLKQFEEMTEEYSDPKAAESHQKILAMTELMIKYFPTLEDEVLLNFYACTYCLDENNSLRGQLFITRNYACFNSTSQSVEVFQKPISICLPFKEFLTIELTSAKRLLQPDNLQIGIKDKVFVFSLHFHRREVYRALCCLCDAAMNRLVKGAELSVAASSDMYAKGNTTGDLANNLVNRGGGLLSISMGRSRDEVNFSPISALPGVSDLGEGDFTDEFMEIDTSPNTVSKNEILQKQKELEKAKSDLLYSSITTLNINNMVDLDFQLKNNEFKNVFRLPGDESIILEENPCHLYQKLSGNSVTGTLFLAQDFICFSSAVTPVNAVIQNLPSLPNIYGYLGVQNTLLIPPATNLTSNSLLFENSLESVISFVIPLPHITSVTKQPPTALNTGLKINAFAISGYLVITTKNKFEYWLSFSSLKNRDKMSVDLLQKIKNVDFRFDNDVLIGEREGKVLKEAMLKKKENRFRSSSLNDSMDDVAFHSLTSKKKVEAEILQSPLRLKFGKDPPKVTLGNVNPNQLWEEYLELSGKDVCIVKDFKKIRELILKTDGIPHHLRGDFWMLFTGAWYSRSDADYYKNLVEEKSGKVGPFTEEIEKDVHRSCPGHPAFQSPIGLGALRRVLTAYSWRNPVIGYAQALNIISAVLLLYLKEEDAFWLLCHLVERLLPDHYTKTLVGSVVDQSVFGYLVQTHLPSLWTHMNKIYLDLSTVSVPWFVCLFLNTVSLDCGIKILDCFFLDGPKFLFWFALSVLKLNEKKLVKAKDDDIFMSILKNFFQRLGENDTEKDSETVDIYNINGMLLFEHTLTLSYGVYAGLVTTDTIECLRSRYRLQVVHQMDSNNRRSQTRTLQESVSLTIEEVEAVYDEVRILDFAKEERRQHVEEFKRFLTQEHDEEEELREILINQGGWGMVKPNQKKAVVKNLDDRSSIGLKDFRKLLTKVSPWKSSFLKPKKLENYSPLEKLLPQNLSEDEDIHVPLLDRIYVYSSVHFNLVRLKRGGADPNFVKDSYIVDLATVINILDIILKQPLNSRLRFLFDIHDVDGDGFLNKRELKSVMDSLLEMFEQARHLDSNIKPKNIKTLNLATENEELYLKAVSSFLSTALKLGSSKGAQTYGENSNNNNVINDKKGKFSSKLAFTDSADENASTDIQTIDEKSNKFNELLEGDLTNFDESKKSRTKSNLLVDTKKKKLDSSYIDKSRQNSNSSSVIFANEGIHFKLTFNEFLLAVLSQSIFVSYFERIWKIIHEDSTGEIFLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1E9</accession>
    <name>A0AAD5U1E9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_003654</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000240">
        <property type="protein sequence ID" value="KAJ3221270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1E9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2230">
        <property type="entry name" value="Uncharacterised protein YcnI-like PF07987, DUF1775"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038507">
        <property type="entry name" value="YcnI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3221270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="616" mass="67478" checksum="7FA7292F5CB90349" modified="2024-05-29" version="1">MNQILTSESLSYINLILSKRSSDTDETDSKLENPMFKQGFVILVICVSVLSYLYRETKETKSELTADVELEKGDNDTTFESNVSKRFRKGAIQQIQVELLASILSSSDWLQGAYVYALYSAYGYDVQEIAILFVAGFLSSAVFGTMFGSVADKFGRKLMCLSFCIIYIGSCLTKLSDVFTILMIGRITGGIATSLLFSVFEAWMVSEFYSRGFNEELLSDIFSWQTFLNGLVAIVSGVFANTIVDFFGKGASGYVAPFMAAIVVLCISFFVISTTWKENYGKESTGNLPSSSGNSSMMDSFRVIKNDFTIFAIGSMQCFFEGAMYTFVFMWSPSLEAVNAFGGCQGSPMVGLAITVPVGLQNVQFAEAPNWQMASTLDENTAPPSTLKRRDAIVSKLEKRQNGTAPSDPLAPSLVTFGTKVFTVIPQGTGIPSVIITSKPPRPFTKPPPSTVTITNEVEKTAKTNRSTVTIGPLPNLATNVVSFTGYNLDPSFYQDFFFNATIPSSLVNGTLFFFPVLQICVNESIRYTNIPADPWGTPGPYDAPRLVISVPKIFAGAPIISKFFNFATAVSIETKNIDVKNPQIGNPNREIINIATPYGVFPDDIVEILKMLTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1I7</accession>
    <name>A0AAD5U1I7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003547</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000232">
        <property type="protein sequence ID" value="KAJ3221400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1I7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001025">
        <property type="entry name" value="ATPase family, AAA domain-containing 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019145">
        <property type="entry name" value="Mediator_Med10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09748">
        <property type="entry name" value="Med10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="204"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="532"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="785" mass="89426" checksum="7718B55D24AF8681" modified="2024-05-29" version="1">MNENEEIANLTKIENQILKLLDAQYKLSLTIHDFQSSAVLHERVNNLIIELRNLDNLKNLSNLKIPPQLIEYIHNNKNPDIYSKQLFQSLADKNQKTSGRINAIKVYIGLLLPVVQVNDVELVFAVTKINDKNEAEVYYKMEDYSNEFEIEVEKDFTISEKNFDIKKNFLIKNSYFINLELKLKSALEAAFYVDNLYLKMNIKPPISVALVGANGVGKRTTLRKFCIENGISIFNVSLSETCNYLESLQFSGSKISNSTTYSPFRAAIEKARLCPPSLILLTDFDLAFQESNKKTSMHLSNHVSFEIDRLIEVNHAPGFSNEICIIGMVDDPLNVPSQLQQKEFFNVYVNFELPIEAERCLIIKSLFQKYHVGFIDATELNNHQEFYASELAQATEGYTIDNFNKLFYHALEYPIRNRAKDSKVLKDGLENKNLITVTNIFEKMSLSENGATTFEPLNLEDKQYTVDFKKDFFSALKLYNPKTDLEFQTHFNNNTLAWDKIGGYENVKKRLEQILIWPFKFSKTYLNLGIDAHTGIILYGPSGCGKTALIHSLAAASFMNFIELKGHQIFSKYLGDSELTIRKAFASARKMAPCILLIEELDNIGTKRGFGDDGGTGVGERVLSTLLNEMDGIQSNNEKKIFVVGCTNRPEMVDEALLRPGRLDVHIYVPLPNKEDRIKILSILTNSDSKNESIVNDEIDFENFVDATEGFNCSDLVSLLREASMINLKEHQDKTTDNLLSKNDFILALEGGNVFCDETKKNLSKNQWWRPGSNTDVKKYERFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1L0</accession>
    <name>A0AAD5U1L0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RasGEF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RALGPS2_2</name>
        <name evidence="6" type="ORF">HK099_003786</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000252">
        <property type="protein sequence ID" value="KAJ3221092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1L0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042214793" evidence="4">
        <location>
            <begin position="21"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="5">
        <location>
            <begin position="135"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="511"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="809"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="815"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="832" mass="94238" checksum="F3AF0730D3DBB78E" modified="2024-05-29" version="1">MRGVLALIKVVNITFDLLIAQSTSILEFLDNDENSAKFEFLDLSNIKGMLAVCQTCLDKTSEFFNTAKFEKPKLVRQRSFSKKHSSFTGAEIPQLKLKNDNLPMSPLLLMYIDALKEITDKTTEKNEKIQYDKPDYTSLAENSEKKKQKMGKILSLIQFSASSLSFLSFKSSVLAYRLCIIQQDLFCDITTQDFLLYRMVESTILEDLSFNDRAENIMQWIHIANKLLQAKNVQTCKAVVCALGTPPILRLKKTWPLVSKKMLERLRHINLLLSEQDNYKNLRAWMAENKDTPGIPFLGIFIQDLTYLRCLHDTELKEKRKKEILDTFENFKNGQKYTYEKFVASVKNISGFNIPKNGLEYNKLKGYLVNAKQMEKDSVGLLAHHWLLTRKKYSEKEIDEISSSREPKSKSQENFYKVNFTNYDGINEYITLDLSEAFEYLSLNNLDIPSQDFLNSFNNSEELYPKSPKMSKRKLTTSSTIKGVLGFGTGINKKDLLNEPNDPLELLQLNENDVNDTDQERGFSTPTSTSESTATQRIKKKAIGIGMGMGMTLNPFHSNLKSNKKSFQELELVEEKSSANLNNNSETSVSPVKGISESTSTNNIKNYLKATKSTVTRQLKEKETAKETNNQTNNKEENLSILPSIVDTNKTMLQQTLILNETLNFYNLKNDGNLTGNRGSENESESAIQSARSSLISINSLNSLNSFNFVLEHLIDDELMNSSNDNDNSSTTSGRVENGKIRLNTLSNVDVQQPPVNTDLNSNESNVASVAVFITPDKFYSSPSSQICPSEKVEKNSFKKIFTDSKSKLHEQFKLPNSPSIERTNTTSGFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1N5</accession>
    <name>A0AAD5U1N5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000335">
        <property type="protein sequence ID" value="KAJ3219573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1N5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF38">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="23"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="126" mass="14487" checksum="5988BDFC3E2B2614" modified="2024-05-29" version="1">MVHPTYLEPENLVSILRDTSKVSGKDYLIIDVRDEDFEGGIINNSNIPCHEFLENIESHHKKLATVPILIFHCALSQVRGPKSATRYANLIRNVALNTNQKVYILRGGFDGFKQQFYVSHRDLFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U211</accession>
    <name>A0AAD5U211_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000389">
        <property type="protein sequence ID" value="KAJ3218253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U211"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="15724" checksum="F6AE768736F53BA6" modified="2024-05-29" version="1">MNDTCVSTTLSLIPDLMSACDITAEFTEFTVASLDQYCNEGACNTAWVKYFNAQKAACTIEGGGWTHWNPETCCANKQKCFDETTKFVEELIANSTETASVSVVSTASPTVPANTKASTTASAKSSATSLNKGIFSLAAMVIVALYMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2F3</accession>
    <name>A0AAD5U2F3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Chromatin-remodeling ATPase INO80</fullName>
            <ecNumber evidence="13">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">INO80_2</name>
        <name evidence="18" type="ORF">HK099_005469</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the INO80 chromatin-remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The DBINO region is involved in binding to DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="13"/>
    <dbReference type="EMBL" id="JADGJW010000427">
        <property type="protein sequence ID" value="KAJ3217438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2F3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020838">
        <property type="entry name" value="DBINO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF2">
        <property type="entry name" value="CHROMATIN-REMODELING ATPASE INO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13892">
        <property type="entry name" value="DBINO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51413">
        <property type="entry name" value="DBINO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DBINO" evidence="17">
        <location>
            <begin position="144"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="383"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="209"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3217438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="622" mass="73742" checksum="6EC5A62EB2110715" modified="2024-05-29" version="1" fragment="single">MTISKDDIHKKKNTNNEEPKIEQINKEYEIMENANKIKNLEEVEELSEELEFDKTDQQLLASLIESHQRKKRLNQINFPRIKKGRKKFYQKFLVQYHKKCKVSERSEENLLIKNEKSSEIEEEENSEIEENVARDFIEVKYKKIWKKISTNFLPKAHKILTHSNQVKKANHKKIAQLCAREVEKTILKERQIQKKDLVARTKKATREMLQFWKKNEKEEREERKKYEKEELERRKVEEELREAKRQARKLNFLISQTEIYGHFIGKNLKDISSNLNLENNEKNADDDMFDELTEEQLEKKAQLNAKIALEKQQEKTKLFDQDVKSKRLEIEGDLMNICDEELIDKIDFKHNEDEQNNKMDVKQPEILTCQLKNYQLKGLKWLANLYEQGINGILADEMGLGKTVQSIALMAYLAEAHNIWGPFLIISPASTLHNWQQEVEKFAPSLKTLPYWGNVNDRKVLRSFWNSNKLYTKDAPFHALITSYQLVVTDEQYFRRINWQYMILDEAQAIKSSNSARWKTLLNFNCRNRLLLTGTPVQNSMQELWSLLHFIMPTLFEIVSVDSDISDCTMDIKKNEHLEMLSGTLRTTLQLLKTTKIYLIQKKKLIIEKELLLLRLSEIQPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2J0</accession>
    <name>A0AAD5U2J0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Translation initiation factor eIF2B subunit epsilon</fullName>
            <ecNumber evidence="6">1.3.3.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">eIF2B GDP-GTP exchange factor subunit epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_004804</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:25576"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.4" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000350">
        <property type="protein sequence ID" value="KAJ3219173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05787">
        <property type="entry name" value="LbH_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11558">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044123">
        <property type="entry name" value="W2_eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="10" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="15">
        <location>
            <begin position="404"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3219173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1919" mass="217822" checksum="6DA6D9035579405E" modified="2024-05-29" version="1">MSRKLEEEEEVLQAVVITDRKSRWGKGSIPDIKYVVSQELYSHGDALRELDQKGLLKSDFVLVSGDIISNMNLEKALKEHKARKLTDKNSMMTMVLKEASPGHRTRSKGEEGLFVLDAKTKELLHYESLEVYPPKKKVEFDIQEIFKYHQEIEVRNNLIDCQIDICSLEVPPLFTENFDYQDIRKDFVKGILESEILTKTFYAHILTGEYAARVRSTQMYDSVRSAVLEHHVTIGRSTEIGDNSKIKNSVIGKGCIIGANVIIDGSYIWDNVVIGDNCRVFQSILADKTHVLNNVHVSKGCILSSKVVVGPDVVIPEHTKLFLKEFLTDENKDANIEACVASSDLIGVEGNACLWNDAFDGDEDEDIDPRNIVLGSIGYEQEMNEEEYPETSDSEISDSDFQFRSKSEIAYDEIAQVTQRALNEGLENDVAALELNTLKMSLDIKFTDLRMVVGSKLIEIIDLNNLADGSRKVIERWGGLLQKFIFSELDEVETIGFLEDHCLLESEDRTKKITLFMYFLKYLYDQDIISEEAILKWHGAPNEKSTEVKASPLLSNWSLCYTKTQVGMEKKIAILGGGISGLSCAWFLAKSTLNAKIMLIESSNTVGGWIKSKKINNALYELGPRTLRPVGEAGAITLDLVHKLGLEKKVVCVPTTSDAAKSRFFLFNGKISKLPTSVKEVLFDRTGIFHRTLLHLIKEPFVKAGNEDDESIDGFFERRLGSSFAQNIVSALVHGIYAGNSKKLSIKSTFKVLWNLEKRDGSLVRGMLRRWNKEELKNSVSEPMFDATSRNFIEEVQKNSIYTFKDGLQTLPDALYNELLKMPNVEIKTSTECLEINLSPGSTEIKVYEKCVKKAYSFNSDHIISALPATSLKDLINISYLKDSLSKISAVDVAVVNVCFKGRDILPISGFGYLVPSNSGSKILGTIFDSCAVPEQDEGLDITRVTVMLGGHKFHQLFGDPGKVPKELMLNVALESIRENLGISPQPMGTLVSIHKKCIPQYNVGHQEILNNVHDFTLHENLPISFIGSSYQGVSVNDCVMYSKKVVESLEKKIKELNTEEFEKPDFNVITFVNNILCQPETQIYSESSSTDKFDKNVNSLESKATQKLLNLQLLSGELSQNLDLLSEQTQKNLPRVLIDLDQIKNHTKNLINFLEATRINLEKNEKDKSCFETLFNLDKVKSRMEKSRDSLKEAENWNSLNSEMENIFKTTEYEKAAKRLGEAQRSLHLLINAPDYQDKKTLLSKLLNQFESSISPQLVKSLNEHDTENVKQFYNSFLQIGRGNEFTQFYHRSRKFKFIKLWSSFEEDPSIKNLDINNEKAIIDWMSKFFDELFMMLNKEFNWTANVFTNSKEVLIELIQQIFNSLKPSLSTRIDDVIQKLGDQHVLPLIIKIYLKSLEFGLKIENLFRQSFEKNQLSQQYEESLESLAPTSNLHLNNSTLNALIIEGGSWGHIIFQEFISFQQSYGKLEEKFLLFQSNSLLKFDRKVDNLELGKIMLDSLIPLFKHAEAALTRCEQFTNGYGAAGLVDGLDNFWKSVLNRFSQILMIISTESGVNNLPKPSKSPKNIIKAGISPSRSSSNSSLQNYLQEADDEMEDSFISNGNLGQDWTNFQVGLRILGVCLTFSKKLSAFDLELKKFISLVNTEENNLNSLKQGRMCHSSLSLLTSSTLNSFKLHTLTESISDKGLEKKDLENFNNNASNGLEYCLLKNSVRNLRIFISNAQKFVFDTLFFYINNYLQLIPTMEVWASEQNKIVSSFGLTIPQFSLSPSAFITRIGEHLLTLPQQLELYTDDEALGFSCHTLPYLEKDDLELIEEEEVWHLWLISISRGTMLKLVEKVLLIKTLSVIGIKQLKTDLNYIINIFEKAMDIEINLQLKKLLFFLELENEILLEADFVNSNKLVGWEIDIFEKVRDMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2P5</accession>
    <name>A0AAD5U2P5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Synaptobrevin homolog YKT6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">YKT6</name>
        <name evidence="15" type="ORF">HK099_002676</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000190">
        <property type="protein sequence ID" value="KAJ3222136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15867">
        <property type="entry name" value="R-SNARE_YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000020">
        <property type="entry name" value="synaptobrevin homolog YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045848">
        <property type="entry name" value="R-SNARE_YKT6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806:SF1">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="8" id="KW-0564">Palmitate</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Longin" evidence="13">
        <location>
            <begin position="11"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="14">
        <location>
            <begin position="143"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3222136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="429" mass="48708" checksum="91BF5BA05E269074" modified="2024-05-29" version="1">MPVFSLQVQYLNTKSSTPTATILAAEFELSSFGYFQRSSVQEFLNFNGKLTAERTAPGMRQKIEIDAYLGHVYVRNDGLCGVIVTDKGYPTRVAFSALNKILDEFADKFPSSQWPELNPSITSSKFPLKLLLDKCQTPESNDPIMKVQKELDETKIVLHKTMESLLQRGEKLDDLVTKSDQLSAQSKMFYKTAKKTNSCCNMSGLNDQEVANEMNKMVAFIKQEALEKAREIKVKADEEFNIEKAKLVRQETLNIEAFYQKKTKLAEVQRKIAQSNHVNKSRLKVLQARQQMLNELFLEARKRLPIITDNRESYSKLLSGLILQGLYQLMESKVTIQCRKKDLEFVKAACEDSKAAYLKNFPKLSVNFEFDEENPLPENCPGGAVVSVMQGKICCANTLDARLDLLADKMLPDIRILLFGVSENRAFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2U9</accession>
    <name>A0AAD5U2U9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RCK N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_005112</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000387">
        <property type="protein sequence ID" value="KAJ3218295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2U9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003929">
        <property type="entry name" value="K_chnl_BK_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF10">
        <property type="entry name" value="SLOWPOKE 2, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03493">
        <property type="entry name" value="BK_channel_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="12">
        <location>
            <begin position="299"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3218295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1002" mass="113395" checksum="EF3DA8CE4328D02B" modified="2024-05-29" version="1">MTKSINSNPLIAQADIGGSSYDVASSSSFAFPPNLADNRERLAFYLDSTKVGRWWEVFDTILNSMLCINYVFLTQFKWKNSLFNYNSIFHPNDVYKFQLLDLVLAITLLLQHLPMIYVSFDRVGSCLSLYSVLTFAATISVFCAFFELNNNSLTFLGSGYWSYDRKHSISESLAPNKNFIFNLSSVTHKGIHILVAILVTLVTIAAWVHLILIEDEKVSPKSSFFDVFYTITLSATNGLDTDIVPDNNTSRIATLAIMIIGAIYIPKSLSEFLTLLKQQSKYDKPYNSALNNETESSLFKHVILAGNINDVGALRSFLREFFCEDHGPQTITTKLVILQPFEPSEELELILNDVAYKSKVQYIKGSIISFSSLQKARADTADACFLLTSKFGTDGDLEDIDANTILRAHAIKKYNPRLPLFVQVLLPRNIVLFQNLAEHVLCIDSYKLGILSQNALAPGFINLITMLTTSFSDASKKFFYYKNSKFDEWIQEYIAGSTQEIYTVRLYINYKGQLFENLASNIYQKYGALLFGIGYESKKNNSNSFQISLNPAGYVFKGTEMGYLITSEKFLAEKIAKGEGLKEEEFRNDYDVNSILSFDFPEIEVEGIDEINEASTSTNLSSVTEKTPLLEKIGNREKGFINNASDEMLYSENVERMRQNISGALRKCNNSGSLSDLLYRGPKIEGNNSQPENLRKLSSLQFLNNLSQDSSIFDLSNLNVLPEFVKKHVLICDLSSSYPANLAYFVAVYRHKDPFTPIVLLSKEKPGVGVNDENDDGTLNQESWKYLEQYSNIFHVSGTPLKRKDLLAAKVESISSAIILCDPFAYESGDRLADAAGLHSLLSIEELSPKGVFISIEFVHEENMKIIGKEDYGKGPSSVTLENFGAAATPSFISGNCFGHFVLHSLLCQVYYNDEEEYEEDEEKKIKKFFFNQLNNFNLTYHQLFLYLLKTKSCLPIALYRRINQTNETQHYYTVLNPSFDLSLRHDDRIFVLSRYKLVDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U315</accession>
    <name>A0AAD5U315_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000163">
        <property type="protein sequence ID" value="KAJ3222699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U315"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="43252" checksum="B6A81C23B806EA54" modified="2024-05-29" version="1">MIIPSKKGNSHISKIDGKRNLTSLPPTYPLDFNLYTVDLSLEKLNVTKLKEERLFRLKNLEDAKINLEKTRIEKKILNEKRKAPGLNNNGTILQPTPISNKEYITGSNEISETPSFDKNDAFFKNLIESTKNTSAEIKDTTFEKKRKSFNYSDFEVSTPPPLPWDINDNTSEKSDIQELIGLMSIQDKKNVDLDKLKTVNHIQKNQDYMDTFPQFSSNQQLQTLQSSSPNLTQNYFQQQHSNNSQYLNNHQFHGQNFSTQGNQIQRTPSLPNYHTNFFTNNSSLVTENRNSTLQYQPSPNSSQQSQHLPMNNNNIVHKCLVMGFPLDKILEALKLKGHDENKVILLQLLINLIIVGVGALTQKLLMHIHELNENLVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U379</accession>
    <name>A0AAD5U379_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein fam72a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FAM72A_1</name>
        <name evidence="3" type="ORF">HK099_001776</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000154">
        <property type="protein sequence ID" value="KAJ3222891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U379"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026768">
        <property type="entry name" value="YPEH2ZP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31841">
        <property type="entry name" value="PROTEIN FAM72A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31841:SF1">
        <property type="entry name" value="PROTEIN FAM72A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14976">
        <property type="entry name" value="YPEH2ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="339" mass="37569" checksum="C8FB729CBD49BF9B" modified="2024-05-29" version="1">MSSNDQSSSQLSRGSRQDSNHHSNRWSLHDVINMTSHREQQSSRYTPRTETNLTIRPAESETNISSASNYDSAYTYGFQSASSSLRSILETRRLMRSVERGTSASNLETTSSRNQSQSELVTEDAYSYTHPPSVSTGTSRPISQTPHLSSARTNSATSIIVPSQGSHTISSSSSFSEYQNARLNIQPAGIFERSFLTATSSQARPQFRSKAVCQLSCKYCGNGVCRRGMKAILLADMALFSTDMPPSGVSLVNEDYQTRKCFCRIRDVACLGCGNVIGYHPCQSCMDACNNGHFWMFHVDHVNSTERMNSSGTKTLLWANLTRADADVEKVDCYDEMCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U400</accession>
    <name>A0AAD5U400_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein tyrosine phosphatase domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PTPDC1</name>
        <name evidence="6" type="ORF">HK099_005321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000408">
        <property type="protein sequence ID" value="KAJ3217837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U400"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000157">
        <property type="entry name" value="Protein-tyrosine phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="58"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="73"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3217837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="605" mass="70240" checksum="27CB339990683FB6" modified="2024-05-29" version="1">MARPSTRLLKNYNLIEKFGIHAIFNLQESGEHASCGDGNEEKSGFSYLPENFMENDIYYYNFGWKDMDIPELSYMLNIVQVMAHMLREGKKVAVHCHAGLGRTGLTIGCYLVYGEHMEGEKAISLVRKKRPGSIQTKKQVQFLLKFEKYIKSLMIIFPQQKVTAVNHQKQSETLQKSSSILHPTEDLDSFRRLSLTSILRKQRLYHHGLEQRQFRHIPKIVNKVVHRLIDLTQSKSVKMKCFAYMKEFEYSTEIPRHVREYQVEVNEDVWFGLDAETKYSYLVDVLFYWFLSLRTPLLDNSQLLLIYQIPGPNLILPADCDQNNNNIEGLPSKKDFEDLYEKTTEEVIFREKLKLMNMETVFALDMLLELFRKKNFKEEQESPTLNENAYVFTKSYNGSYEFNDESKEDLEIFKKISKILTVKYNYNSNSTKDDTGPLANSIILPIIPDNNLLSSPISNEEKFQIEKKILKVREEAALEEENLKAIKVSNFLTKLRDINLSQEGLFKINSNDADDNCSSIYSNQFTLSSGKDQSAIPILPKRSSSLNANKNATFKIKRKEVARDLLLQFPEKRDNIDRKDLETDALEVLKKEFIELPNLPTKDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U415</accession>
    <name>A0AAD5U415_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">IQ motif and ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003787</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000252">
        <property type="protein sequence ID" value="KAJ3221093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037695">
        <property type="entry name" value="IQUB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057887">
        <property type="entry name" value="IQUB_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21074">
        <property type="entry name" value="IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21074:SF0">
        <property type="entry name" value="IQ AND UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25805">
        <property type="entry name" value="IQUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IQ motif and ubiquitin-like" evidence="6">
        <location>
            <begin position="471"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="840"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="882"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="924"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="951"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="984"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1044"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1093"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="672"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="818"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1216"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1332"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="679"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1225"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1332"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1360"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1379"/>
            <end position="1388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1388" mass="157242" checksum="0A76F111C47CB211" modified="2024-05-29" version="1">MSNNEEDFKNASIQDEQLIKNLESETSKPQTADDHEGSRDSKPLTAHSNTSKSSDDSKAAEIAGIANNDHLDLSIRNSEVKNESKENLQILDNSEIIQVETKAEIQQFELNSHPTTADTELQLKFEVANSTEVEFVEEENSQVLMNIQSNDAGYGGEFESEDQKESRDSNHINVEANEIIHMPEMQNNIEQFIDVEVQASQPKDEITINFENFDEDLQTKAEGGEKSTNDSKFVEFDKSVEGEEFKSGLISSNLNTWHRKLYMGGYRHKETKVEYFHSTTQTTTAQEKKAMAAAPKNHRDTQTKFTRNRISQATVESSTQMTKPGVYVSTETDYELTPSKYVTADDFHAFIEKTVIRIQCFIRRCIACRIVEKKRKEKRIRGMALAAKEKRRKQLAEKRRNKEIESRLHPKTSKDFEILYNGLENWRIQETQKINNANFSEPARLTALADLLDQEASLIQKIDRLKITANEENKELSIVNLLDKMSSPKKWAVHSKLGGFCSVDTPNTIRARELRDLYHALNIPLLSVDERLQILLHVKYTVKEFDCNLTRDIVELIDREGDLVSRGREAKSLEGLRRRISNLFLQFIQTPEFNPESKAHQKFPDAGQSWKREQSVYYCRGCTKYLASTEFYLSTTMRHLGRCKLCTMKENIANQRKDDSCYVEMLKMARGQEVAKSQNDPEDKFSKENGESEQGKQSYNAISLLQESDIRYLVDTIWNRQSAVSGSKKIEELVLTRWNPKLELSPWNVILLTVSEASNHEMQEDPESVYTDEFVRRCQQRHIAAKKHFSSLPYMEKYLKGKFNHKDVNGFNGLNDEVKKKSKKGGSDNIITPPSLGKKEDSVNDVITSLSFKPSMTQLASSSMDNSVMVWNFKPQLRAFRFVGHKGVVTSVDFSHTGNVLASSSRDNTVRLWTPTVKGDVTVFRAHTSSVRTVQFSNDSEKLLTASDDKTVKFSPDAKLVVSGSDDKTLKLWDLNSKTCIKTYFDHIGMISSVAFHPAGTIVASAGIDKSIKLFDIRTHKLIQHYSDAHLGANVDGSTTQGGVNSICFGGSQGEWMISSGMDGLVKIWDLKEGHLLYTLYGHKYGSTTAAVFSPKGDFFATGGSDSQVMVWKSNLDSISKVAESFRNEKNETFKEGNYMQKDINKGIEFSPPKQIPNLHQEPSVDYNRQNLNRSPIVQQASGGVTKSIYNESEKSNPLILNIGESETFLNHQIGSSNRSISSSPVNNGSYRSYSPSRLNTSSPISQFQPEYEDIPAITSNLEVQNENISSEDLVNTLKTLTNQINVLTQTMGIFETRLAMNEDHVQNMDSRFNTVLDRMERILNNKETPQINKENQSNNYNNNSSILKNNALNSNNLNNEKKITTSEKSKNLNQQQEVAEETDFFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4B7</accession>
    <name>A0AAD5U4B7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_000684</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CYC8/SSN6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000117">
        <property type="protein sequence ID" value="KAJ3223791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4B7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017053">
        <property type="term" value="C:transcription repressor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000403">
        <property type="entry name" value="General transcriptional repressor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000078">
        <property type="entry name" value="Transcriptional corepressor Cyc8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051630">
        <property type="entry name" value="Corepressor-Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017:SF1">
        <property type="entry name" value="LD02225P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4 9" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="190"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="262"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="296"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="330"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="374"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="455"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="383"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="460"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="480" mass="54889" checksum="FB1C51CC654CC701" modified="2024-05-29" version="1">MSIVQKLALKNEELWSQMGAFCESLGETERAQIFYENALRNNPNSIQCLQQIAALCQNREQYAAAVEYFQQILNLEPTNGEVWGAIGHCNLMMDELQKAYSSYQQALYHLSNPKEPKLWYGIGILYDRYGSYDHAEEAFTSVVALDPDFEKANEIYFRLGIIYKQQHRYDTSLSCFRYILSNPPKPLSELDIWFQIGHVHEQKKEFLEAKKAYEKVLAENPNHSKVLQQLGWLYHQENSGFTDQETAISFLTRSLEADLNDAQTWYLLGRGYMAQQKYIKAYDAYQQAVYREGRNPTFWCSIGVLYYKINQYPDALDAYTRAIHLNPYISEVWYDLGTLYESCNNQISDALDAYSRALELDPNNPHIKQTIETLKKQQASGVKSHGQLSSSKSQISSNLGPNGVHTSFTGPNGPPKQIRENAHSNANIGARPPQMELRQDMRPVGGATAIERQQQLPSMNTNNNNNSPPSTHHSSQRERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4I1</accession>
    <name>A0AAD5U4I1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enkurin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003407</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000223">
        <property type="protein sequence ID" value="KAJ3221562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4I1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027012">
        <property type="entry name" value="Enkurin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052102">
        <property type="entry name" value="Enkurin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21490:SF0">
        <property type="entry name" value="ENKURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21490">
        <property type="entry name" value="ENKURIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13864">
        <property type="entry name" value="Enkurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51665">
        <property type="entry name" value="ENKURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enkurin" evidence="6">
        <location>
            <begin position="172"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="268" mass="31037" checksum="2121C7146DA66248" modified="2024-05-29" version="1">MYPKVLSAAAEIQDSNKFYVNPVPPDPFEESVHKLIPIELRKEEKAARYKSVHAYEVKAEEKKGKKLAASMGKVNIQPNPPQEFLRKGDGNVRLIPAEVFQCDKTILRDPLPKDRGIIPKPTEKDFIKLNALENIHSIPKKTKDEGPNYKEKKDYGKVPGYLAKRITEQQNIKQQRELEYSERKIMEKRQSELERGLVPLPEEERLKILNGLKNNWERLNSDYQKLSLTVDTVPKIARKVNMEQQLKQLEEQLAKFSNSNIMVNFNSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4W9</accession>
    <name>A0AAD5U4W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008332</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP domain-containing ribonucleoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000090">
        <property type="protein sequence ID" value="KAJ3224533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4W9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052240">
        <property type="entry name" value="SAP_domain_ribonucleoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551:SF1">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="61"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00046328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="217" mass="24113" checksum="80A4C7C56D3C8FEF" modified="2024-05-29" version="1">MKVSDLKIELEKLNLLTSGKKDDLIKRLQDHFANQTHENSTLMKDAPSAKSVELTSANITTPNTATHSEGININQQSLKNTSSPTVTSSLTRTAALTEEERRKLREQKFGTVSSSTNKANKMQDKLHEREKRFGTSNVNTTARNSQNFSKLGTEAAGLAYSKEDLEKMKAREEKFRTGGGLVSAESIGNNVLGNSEEEKKRRREERFGIVKNGDVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U523</accession>
    <name>A0AAD5U523_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007899</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U523"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010828">
        <property type="term" value="P:positive regulation of D-glucose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090314">
        <property type="term" value="P:positive regulation of protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031340">
        <property type="term" value="P:positive regulation of vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038983">
        <property type="entry name" value="C2CD5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057815">
        <property type="entry name" value="C2CD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056430">
        <property type="entry name" value="C2CD5_YbjQ-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412:SF2">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23028">
        <property type="entry name" value="YbjQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23128">
        <property type="entry name" value="YbjQ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="226"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="C2CD5 C-terminal" evidence="3">
        <location>
            <begin position="455"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="622" mass="69207" checksum="02598EB7C6C0559B" modified="2024-05-29" version="1">MQIFFFGLKIQISVGENMITGVATGTSIFVKALPLPPSLKVLRNIDVVDEEDVKLLEVQKKIQIQSEQNRMKIESALNEKDIIENVEALFVSKKDTEAGSESIMQQNSDEVAPSRSDFPKKKSTTVGQSSQIDGVEAITDVLSEDGSSGESSSESEFDELMKSASNSLRHRLVVVQIDDEQDEDLVLLLDPTFPVGFQLLNLEPTANLIFNSEEQKKTGSQQNFTERSQSKLQLITLVKQGLIHLQHHPNRQLAEIFKTMYKEIQLQLSYFSPCIVAGIEYSIKLPQENEVQITMIAACIGQSLPLNDLEPEYQEDDSVNLFKLENLTDRSGYDSPKSSKHGSASLNESFKFRFSKFQAKPSALNVSKVPTPIDEKFKSPSVSEEDFNPIQENDEEYNSKSLNVSSRFHTSQSEGIDLENGNSRSNISNPRENTVTDTGVRNSNMPNNNIPFVELTPLKSVQNRRILKFLGRLSLHFVKEANIVFETGLGLSGMGGFTHEFWCEVYSVLRAHTAAQGGNCLIGLTIDQNIFSESIKNQGYALLSCSGDVVFCDPDSAYETFEEEDMGKGFGEKLFGEVIDFNILGGNNIESSQWLKASRIGLDFFGRLSETTSTRNSALSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U590</accession>
    <name>A0AAD5U590_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sperm-tail PG-rich repeat-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">STPG2</name>
        <name evidence="2" type="ORF">HK099_007868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000080">
        <property type="protein sequence ID" value="KAJ3224824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U590"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051291">
        <property type="entry name" value="CIMAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010736">
        <property type="entry name" value="SHIPPO-rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580">
        <property type="entry name" value="SHIPPO-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07004">
        <property type="entry name" value="SHIPPO-rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="646" mass="73064" checksum="7B79A20DFE4CE38A" modified="2024-05-29" version="1">MYSRAEKHKADKNANPNLGPGCYTLDEVTLVAGKLLGEDSYAPFSALTKRVCAFDEMISRNPAPGIYEVEPISVHNEKKASLFGRSKVQRFKEVESSTPAPTQYNILGEEKSKSKKFKGAMENSLKLRILEKEIAGLVEVEENKKNWTSESRSSRESLEKRDILNERVKGHSNAFKKGKKLSLSAENRKKIVWKRKYLPPSIPMGNNAYGYEESKAGELIPRKPPKKLIDSGPAYNFLSSFAEKAKYENKGFKFGKDEERLKFDTYNYPSPLQYNIFTGDNFLHKTDSGNGAAVMALAPCVRITDTVIKQEKKKGIPAPNSYNINSPLEMALKEKRRRVNFGGSVEYRNVTGVIQQTKTPGPGSYHPEFNDQKVSGKNKSFLSTTKRFEDKQKLKSYNISPGSYEVEKVDLKLNKMSNVHRGTRNMPFGSYTERFEKKKVNEEPGPGEYEPEIKNSAPLGFSTYNYYNTNKKTGIKDFQKRITSATTGKLTKGKTAKLVLNKDEKVHIPVFGTQRERFNVDEGKDIPAPGSYSVSESFESMKNKGKIDPQSFLTTQTQRELFPNKYCVPGPGEYSVLEYSLPGNKKVKDGIFVSNQERFKEKFVEMVPSPNHYHTADYEQGLVKKTFNITLGPVYDTARPLEKIYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5F4</accession>
    <name>A0AAD5U5F4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000076">
        <property type="protein sequence ID" value="KAJ3224919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5F4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="126" mass="14453" checksum="BE260D34006222B6" modified="2024-05-29" version="1">MKGSRDSNETDSVNSLTSKVRMKVEIEITNVEPILLHADLNNSASKNEYEINIFSKQSYFPISRWPIVLNAKTTLHLVYENNSWVVVKHKDVWLDYTRIDLAPELIKAAWGSLTSVVINTWYGLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5H9</accession>
    <name>A0AAD5U5H9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">60S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS16_1</name>
        <name evidence="6" type="ORF">HK099_002569</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the eukaryotic ribosomal protein eL13 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000186">
        <property type="protein sequence ID" value="KAJ3222214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5H9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000007">
        <property type="entry name" value="40S ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00499">
        <property type="entry name" value="Ribosomal_eL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001380">
        <property type="entry name" value="Ribosomal_eL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018256">
        <property type="entry name" value="Ribosomal_eL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01294">
        <property type="entry name" value="Ribosomal_L13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01104">
        <property type="entry name" value="RIBOSOMAL_L13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="321" mass="36630" checksum="4B6A53FFF88BA0BE" modified="2024-05-29" version="1">MYKTATAVAYCKRGRGLIKINGAPLDQLEPEILKFKVYEPILLLGKERFQDVDIRVRVKGGGTTSQVYAIRQAIAKSIVAFSQKFVDEATKKELKDILVAYDRTLLVADPRRCEPKKFGGKGARSRYQKDWQTRVKTWFNQPGRKVRRRENRQKKASLIAPRPLDGLLRPAVRCQTVKYNTKVRKGRGFTLEELKEAGVRRKEAKSIGISVDHRRKNRSQESLNLNVQRLKEYKSKLILFPKKANKPKKSDSPESALKSVTQLKGDVLPIKQDKNAVSTGKVTNNTVHAYAALRKAQSDARYKGVRELRAKAKEEEEKQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5S7</accession>
    <name>A0AAD5U5S7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Gamma-butyrobetaine dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006812</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000061">
        <property type="protein sequence ID" value="KAJ3225441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5S7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045329">
        <property type="term" value="P:carnitine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2020.30:FF:000002">
        <property type="entry name" value="Putative gamma-butyrobetaine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF25">
        <property type="entry name" value="OXIDOREDUCTASE AIM17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="8">
        <location>
            <begin position="17"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="138"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="47991" checksum="B914AB4E8032EE9A" modified="2024-05-29" version="1">MIFLSSKVMQRHYRATQFSDTIKICWNDSSSPSVFHNYWLRDHCQCSACVHPSNKQKLHSSGDVKVSAKPAIEIAGKNLKIKWQKGSLRTDLEKTHESVFDLDWLKRHSYSPKPTSNLDNSFNSQKLVKLWDKDVYEKEKYEVDYNDITSNNPAGLSKTLDMIKKFGLVFLKNVPTEGRKLNPDSETETISVEEVAKIFGPIRETFYGKSWDVKIVPEAKNIAYTNLDLGLHMDLLYFEAPPGLQYLHSLKNSVKGGTSIFLDSFKAVEYLKQISPESYEILKSEYITFHYENDNHNYHYQKKIIDTSNPNEYLQVNYSPPFQGPIIFENNNKIEKFYKSLFEFEQILKMPGMIFKYRLNPGDLVIFHNRRVFHGRTSFDAVGGERHFKGTYTDWDDFKDLERRSNFEEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U623</accession>
    <name>A0AAD5U623_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000162">
        <property type="protein sequence ID" value="KAJ3222717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U623"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="201" mass="22782" checksum="F9B768ECD0EE4215" modified="2024-05-29" version="1" fragment="single">MLAIKNRQEKLAASQLQQFQLQPQEQKKIRKKEKLASIEMLNKITLSNPDNTQEKKFNYSLYDNCDTSNPFVSNCENAYTNERNIALKFSSQNDLTSGQDTGNVQLSATSVDQMENSTNALYNTKENLSSLCGHIGRVAFKASKENISISPEDIASRLTNPQNMTGIHRYQTEPAKFEFHGNHLNFKVPPKKVKKKPNIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U673</accession>
    <name>A0AAD5U673_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Propionate--CoA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005883</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U673"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050218">
        <property type="term" value="F:propionate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347:SF3">
        <property type="entry name" value="ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="2">
        <location>
            <begin position="458"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="63992" checksum="9EAC13E844E44A11" modified="2024-05-29" version="1">MVYISFYNNSNLFVEIKGFGDQTALIYESPLTSQKKKYSYKELLVKVNLLSIFLRNEGVKRGLTVMIYMPMIPEAVVAMLSVARLGAIHSVVFGGFAEKEFSKRIVDANPVIILTASAGIEPKKIINYKPLVANAIKLSGLNPKVLLFQRKEIPEVPLNDSFGEKDWEKELAIIESKGAENVTPVPISSNDPLYLLCVVRECGGHAVAAAWSMQNIFGMKPGDVFFCASDIGWVVGHTYIVYAPLLSRVTTVLYEGKPVGTPTAGKLWDMVEEYKINAIFTAPTSIRVIKREDPKGELFHKSKIKTLRAVFLAGERSDPATLKHFGTMLGVPMIDNYWQTETGWPITASCFFDGENRTKEKYGSAGLPCPGYNVVVLESEETDEKLGNLALKLPLPPGCATTLWKNHSGYLKAYLNKFPGYFDLTDAGKVDDDAYVHILSRTDDVINVAGHRLSTGSMESCLSTHPNVAESAVVAVHDKVKGELPIAFVVLKSDGNNSVNICEDLKNLIRDEIGAIASLKSITIVPRLPKTRSGKVLRRCLRQIGDGQESFQIPATIEDSDCLEEIKKAFNEKSFLKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6F3</accession>
    <name>A0AAD5U6F3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mixed lineage kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000084">
        <property type="protein sequence ID" value="KAJ3224705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6F3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054000">
        <property type="entry name" value="MLKL_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22215">
        <property type="entry name" value="MLKL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mixed lineage kinase" evidence="1">
        <location>
            <begin position="91"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="941" mass="107140" checksum="003C0EEF4CA132D2" modified="2024-05-29" version="1">MSDFRDIEKKISFENLNAGGIKKSITENLYEKGLDAASKSFDDYTAAKGKFDLLTSGAKQIFGESNPILIQTMSIAKNVLDIGSTIPFVAPIFSVLQVIISIEAKAREADAKCNNLLERINFMVQNLEVLKKVKLESTVEAVVNKMAGVLEDSASLIKIYRKQNALSRRLNTGNKEKFVSCCKSIEEVSKDLMFTLQIQQTSQISVITNALPKDSEDEEAEKFLKAKGGFDNIKNNPELIAEFAKNINVEVPEGIIQELNQNIGDMLQKNNEELSKMLKGEMSSAVADGLKDLAATLTALEKEQILKCVQCDADYREATNAEGSCNFHSAASYGGKIHRCCGKTAEFPCQKWKHTNKHHNKLRYGNYFQILSDISNYSDTVDTWETFELVDYLQGEFKQEWSLGKLLRWKTRASLIHEPILFLKFGNFFDDLNSYYMGFITVADLAAIQDQMIMLKKRSLSIFDGSMKCMDYFTKAEWVLDSNNIVNIIRVSAKVTSFEKLTIHEYKFNPANFELIKLENIQQSWESFNPKSSYNLPKTISVGGFFSDTQIREPRTFKTLNSSEFPIIVLPDEHCSILANSKLANYEGDFFNGKFAIFNKNPTEAMIISKIENFYRYVGVKEYTKTSNFKIESDFPLEVPPKKSVQVEWSCYIERDPNDKIPQLRWWDKSVNARHRPLRLKFLVKGLEGDTASHVLEYVYKPYKQKDLETDTDTEYNFRLDDENLFQSYIEKVKVKEFGNNDTTLVEFSKINCSLNKNDLDSLVFKGKRLNVTEVEIDRKYEDSDGIFKGNLWALIDTNCQRVYAIKVLITQGSFYETKTKAVLGYIPIPNYASSTKTKEIKLAEEKIQFPILKEEEKREIITDDEFDDVEAVTENVKSVPGSVSSNVAGVGGIMNQDLTFLDKRLENIENHIGRTADALETLVGLLKKIVIEEVEYKITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U760</accession>
    <name>A0AAD5U760_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UFSP1/2/DUB catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3227013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U760"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012462">
        <property type="entry name" value="UFSP1/2_DUB_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07910">
        <property type="entry name" value="Peptidase_C78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UFSP1/2/DUB catalytic" evidence="2">
        <location>
            <begin position="266"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="510" mass="59794" checksum="A66F38BAD1838A3C" modified="2024-05-29" version="1">MENQIPCESCSLLINFEHFDEHAKTHGLETKTKGDEMTSKTIPCDVCFKDVNTSQYLEHYSFHNNDTFQNICDAELQHCLIPCESCKESVSVDEYASHIAMHQKDFENVKLINELLNEEKILKLELENFEKTLRKPMEEEDFFIDCELCSESILNKVYLEHQNFHQESDEKVQFNKLKRKYQEYNPNLSFSSKFENNLNSQLKRGKITQEEYSKKIELFDNLKNDPSKVSKGLVYPLFNNFKFLSHSTLKLKLCCKEVENFSFDFDDGSCGYKNLQNLLSSIWNKAPFKSKLVAVFNEFPHILTLQKTLEEAWYAGFDAEGCEQLGNKVYNTLKYIGGSEIYAILSFIGIDCTLVEFHLNKRKNDYEEVFFKYCMDYFDANENSDVALTEKFPLYLQHDGHSRTIIGYEIFKDEAKKQTKILSYLAAESTEDRAPDAVCDTTETTDTTEKIKIFLTKPKYFKYEPLFYFRQSLKSFETFDSYQLLKINNRVFDVGSKEWEDKKILKSSKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U767</accession>
    <name>A0AAD5U767_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar protease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PEP2_6</name>
        <name evidence="8" type="ORF">HK099_003507</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U767"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042209518" evidence="6">
        <location>
            <begin position="17"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="7">
        <location>
            <begin position="56"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="462" mass="50591" checksum="879D1145B8100B64" modified="2024-05-29" version="1">MFYISTVFCIFSYAFSLKVPLSSLANHFQFNSNNANLPTNDKIIEIAKFATEKGGLTAPIQLGQSTMTVLIDTGSSNLWVPGNICRNNIMVLSDCGPGYDNSTSKPVDTSLIFNSTRFNKFTGIQYLRYGDQSIADGQLQNDILTFGGQPTVYVNFEEVIKEYGVDEVGDPNPDMNTITQAGGFNGIGIWGLGFPSNNAVGFNTVIETLFMKKAIPEYLFGISLGNPQDDDVNGQLSLGEIDNTKFTGELIYTPVDPFPSSLAGRFNDEWRIKLSSFKVGDIDVTSILDTENFDDRVLIDSGNSNIKLPSAVYLQLQNIFGATMSVISNCSDNIIDNYPSLTLTFGNQDFTLPSTFFVKRNSVVTSSCRLLFTDGGSARPQRFTLGAPFLKKYYSVFDFANKRIGLATAINAGDAVVPATTTSTTKKTSTTSTTTQNEKSDSTLSQKLNLDILLFIFIAYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U781</accession>
    <name>A0AAD5U781_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RAD51C</name>
        <name evidence="9" type="ORF">HK099_002209</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000171">
        <property type="protein sequence ID" value="KAJ3222536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U781"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000707">
        <property type="term" value="P:meiotic DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19492">
        <property type="entry name" value="Rad51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052093">
        <property type="entry name" value="HR_Repair_Mediator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="14"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="278" mass="31262" checksum="5BDD4CEE92A584B6" modified="2024-05-29" version="1">MESNGLIRFQEETLKKPLTTSSRSLNNLLNGGFPSVLNEIFGPPGIGKTQLCIQLSLNVQLPSSLGGLEGEAIYIDTEGSFTLERVEEMARHICKKLNKSLLTSVEKFLSNIHYFRIFDLNENIAIFNALDEYIKKNKKIKLIVIDSIAFHFRSSFTDLGLRSRILNTLSQKLMKLASDFNLVIVLVNQMTTKLIKGGNCSTLVPALGDSWGHSCTNRILLFWEDGIRNATLVKSPNMKVNTVQFEILNEGISDISTLNVPNVVSRKRPFEEEQNNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7J4</accession>
    <name>A0AAD5U7J4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GAR1</name>
        <name evidence="10" type="ORF">HK099_000806</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the GAR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000120">
        <property type="protein sequence ID" value="KAJ3223694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7J4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034513">
        <property type="term" value="F:box H/ACA snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000454">
        <property type="term" value="P:snoRNA guided rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.230:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237:SF6">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237">
        <property type="entry name" value="NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="127"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="139"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3223694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="179" mass="18622" checksum="A815B3A1888577A0" modified="2024-05-29" version="1">MSSRGRGGAQRGSSRGGSRGGRGGFGGNFNSGPPDVVVEMGSFVHPSEGDMVCKSVNTKIPYFNAPIFLENKTQIGKVDEILGPLNEVYFTVKLQEGVLANSFKSNDKVFIGTDKLLPLERFIPKPKPVGGKIEKPTGKQGGARGGARGASRGGARGGARGGRGGFSRGRGAPRGRVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Q2</accession>
    <name>A0AAD5U7Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Q2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009602">
        <property type="entry name" value="CBAR/FAM92"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21223">
        <property type="entry name" value="CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21223:SF2">
        <property type="entry name" value="CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06730">
        <property type="entry name" value="FAM92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="289" mass="33062" checksum="D41617B953368590" modified="2024-05-29" version="1">MTNRINHANDEKLRFISKEIDITDKNMQRLRHSIESYVRNQTRLRSKTIKMSEVFQDFSDSEAPALSEILSSIAEKLKEREKSREVMSNRISVMCGEPLKIYSTLCSKVKAELKIRDNAYDKQSRKKSSLDKMIINNSGDRSKINQAQLDLLSSSQVVHHSTNLLVESVERFEIQKRLDLKTCLSDFLWSEINFHAKALEGLTKLHQQIHLTNLNEDLIEINERINLASSRPGSPVRSLSNSPSKGHFSHENLSPTKKSYEENEVGGKKILFTNENSLSKRPSLKAGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7R0</accession>
    <name>A0AAD5U7R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001668</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7R0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="250" mass="28609" checksum="F48ABCA1E6BF0437" modified="2024-05-29" version="1">MTTITYNEAVNEMETLKNFSDHLKQKNLNTEEVKINSSCSKNQKMIDAVLKRSEISRRTALFKKRIELAVVKVKYGWTDRTFEEVQTLWYKKYPKVVPRQKPLHRIINSQVQKKKDLAAPPKFTCQVKPNFTFTPPSPSTTATTTTTTNAPYNTSISQTNSLTNTSNLNLMKFSVNTPCCSPKYAQSLKKPNFTQYNCPTDNNNYLRPPTVKLNYLTPEASPLREPKMLRENVINDNEVALLLLDIHNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7R6</accession>
    <name>A0AAD5U7R6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000011">
        <property type="protein sequence ID" value="KAJ3227762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7R6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="80" mass="9620" checksum="FA0D6EE337DC0E45" modified="2024-05-29" version="1">MGKSSKAYRKKTKSEKDLIKIEKQPSNDLKQLVKEKTVELNKKREKIFKLKKKNKLKKLEEKKNKTLEENLDEDQEEMEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U823</accession>
    <name>A0AAD5U823_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Coiled-coil domain-containing protein 63</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CCDC63</name>
        <name evidence="6" type="ORF">HK099_008206</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U823"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051876">
        <property type="entry name" value="ODA-DC/CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049258">
        <property type="entry name" value="ODAD1_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21694">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21694:SF18">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21773">
        <property type="entry name" value="ODAD1_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="163"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="109"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="502"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="595"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="677"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="247"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="405"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="502"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="537"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="601"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="633"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="687"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="699"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="721"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="744" mass="83987" checksum="4FA7F69316B32538" modified="2024-05-29" version="1">MMQHQTSSEYLTFSKYPIHSNILSHSHPSNLMINSSLSEKKIKSFQESLRTVNLSSLQLPPILLRRKSNESIISYSSTSLPSSPVDESYVSYLNLPNLLHKNEEEIQSRLPLFNTPNKKRSSLKSSSSEKKVNHSAKSPSLQKKASSTSSNSNKSSKNKDVIFRCPHPKCKGEKTFPKLFNLKSHMMSHSNDRPYACRICNNASFQRKHDLQRHALVKFNKSLAVNKQLRSTIDNLRRERLVFDNIYKKFEKELMEQKKAMAEIIEMSNSAYEARDEAQAKIIAWREKVEKEHQAYIQEVKDLDRSYEQDRKLKEFMATKAADRLEKILEASGGNLECLSHKKGNKKKDGVSPKFSSQESLSESLEFYEKAFAEIKTVTGVSDMEGLVQRFRAVEDNNFSLFNYVNEINNEIEKYLEEITELQKEIDKMKVENIVADEERKKVMASLENALNTCNEKHLLHEKQYNDTLYTTSEMRKGVNKLVKIFQTMRFSFSGRQAQINYNNQHNHNPEDSGNNNSESHTQQNTVDELGNPINGEEQQQQNQTESNFIPTDNLKFDLGSTATTDTNLIQILGVIEHKMNELMTLNYMFNTPRKIGSAGSNQPTTPSQPNNPSITAEDKFSSGSGGTGGAENTNNSTAPGTATGTAPKEGVLIMPLLGTIGGLLGQGPIAPLGNITIVAPSTGDDHDSEENISDEEDRPMTREELKQKTLRGLSKRERTQGQNSGTQIKLSKQKRQIGEKRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U849</accession>
    <name>A0AAD5U849_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U849"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="473" mass="52358" checksum="C314887032DAC2D5" modified="2024-05-29" version="1">MINNEEFVLSNKVTSSNFEMENEELEKKEKNITVEVIDFLDGYTKLCQQKKSPVVKTIQKLLQVAIDGGHVPKKLDFRGTCNELKYDRINNETLENVLKPLSSSTFLREINLSFNEIGDKGAMEIASYIKCDLTLEVLHLNSNNIGVEGGTAIAQALLINESLFTLNIAYNHIKDEGGMEFASMLQINKKLCTLNLSGCSLNARSIIALSTVLQNNSTMKSITLTDNRSNLSTLTQSLQNDVVMHLSRMLKLNTFLQEIGLAKLGITDWSTIDMLSKALKISNGLRVLDLSCNKISRDGGVAICQALHDHPTLRTLKLSCCSILDEGAEAVGEFLSKNKEINNLYLDHNGISGVGLEAIAKGIMESRSLFRITLWGNIWDVAACEAFSKLIGGVVCENKVGVNEDILPDVLHASNLKNLNVTENFVDSKLYSKNSNKAFAKKCSRLNKNQVDFVVYSVEGVLNIAHQELVENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8B3</accession>
    <name>A0AAD5U8B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Inositol-phosphate phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000981</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8B3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="26708" checksum="D940D48278FA9417" modified="2024-05-29" version="1">MAFQYEKEKAIAVAIEAGDIIKQAFTSRQLSFAPINFKEDNEADLVTKTDQYVEAFVFTKLRESFPNHNFIGEESEAAKENKSKSVDAPTWVVDPIDGTTNFVHATEYGSDRSTKVLKSKLDTISKVICSPTRGIRSLGSAALQCCFVAKGVFDAYWEAGVHIWDIAAGALIVREAGGVFVGFGNGENNENVVKEKVNYCSRRFLAVRPMKGDDFEKDKAVKLLRPLFEDVPLEMDGPFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8I2</accession>
    <name>A0AAD5U8I2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008373</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000091">
        <property type="protein sequence ID" value="KAJ3224505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8I2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="138"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="336" mass="38066" checksum="670F0D545E88FE40" modified="2024-05-29" version="1">MSYSNDFLSLCQSNVKEDLYSLKLLIEQNPEVLQERTNYGRNGLYLACQYNLLETAKLLLDNNMKVDSYMIDGWTPLYHACHTGNFFTAKFLLEHKANLNKRTVAGFTPLHAAVQNGHYETVALLLQHGADVNKATSIGTTPLMIASYFNHLQIAKLLLENEANHSAKNKFGKTALDCSHKRSALCRILEKATGCMRSVDNLNSSKNLPSVDIKLALNAQVNHFDDSAYNSYFNETENNTPVNKHLSLNMNSTSKKRDSVTLEVVKEKSINAFNFWKENFSTSQEVKTTDFLKALELKKGQKLEDFAELHNLENVDQKTFSFLIKEKRGPLLPIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U959</accession>
    <name>A0AAD5U959_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BET5</name>
        <name evidence="7" type="ORF">HK099_008203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Part of the multisubunit transport protein particle (TRAPP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Golgi apparatus</location>
            <location evidence="6">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAPP small subunits family. BET5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000088">
        <property type="protein sequence ID" value="KAJ3224594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U959"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007233">
        <property type="entry name" value="TRAPPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249:SF16">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04099">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01399">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4 6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3224594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="135" mass="15508" checksum="346F6ECBEFD211D3" modified="2024-05-29" version="1">MAFIEEAKLVYGVVFSLRNYMQKISKNPSADSFSSFSTSNYKLVFFQTATNLKFIMSCSINLDTSYVLKILKEIYVNLYLEFVVKNPLIKLNVKPEIVDKKNKNKIVDNANCNYITSELFNSNLQKFIKSVAGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9F8</accession>
    <name>A0AAD5U9F8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000042">
        <property type="protein sequence ID" value="KAJ3226191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9F8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="639"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="814"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="878" mass="97819" checksum="094B4C929EAEF0F5" modified="2024-05-29" version="1">MKSIIRTNVLFKLNQEKNGIYNQPTVRQVLIVSNPTITIEEFQLQILQNIIEIDNKKLLRCRSKNMKDIVDKLEFELFDIGILDHTALVIKNKFGSEISNEMYLGEVFEDGDEVIAQAEYCEAVHSFKNENSKKRCGDSLRSYTTIKKTRYSLSFSKDKDSVDFIFSDELGKKSSIYDQVETESDSDVALKDHQSKLLYGGEGRLNKSRLVPSKTQLESISQKLESQSVSHSQLDSQNQSHISLALGRFSPDISIINPGVKEHTSNDENNFSSLKETPHDIYYSQFNESFNESINELPNYASTKAENYTVSSKNSVNGTDSNISENNFKEMGEEEKILDHPVSNENELVSIENNFSSSQAHMVLCWSPKKLLEHKTISSGDAQASLQKSTDVESEKQYVLKAVQVVHEPTKKADIDTASEASLESVNNETDYNVDQGALYNIKDVEILSMADTTTSEGGSLELENGKSGVKQIQNISNQPSPNENFKNLKKIAKNNIRQNVPTDNDDIDMFYSQTDTQKFSLSSLNLEGGDKLNRFKLVESDDFSTEDEKPEITIKNNDLEHTHLLVMNNTQESEKFLAEHQNLKDLTQKVFAYNQLVIDDNELSGDSTSFSSSSDDENAVSNVKKQINEKVILKQKSITSSPSEKTLSSDVKQKLKATSQGRGFKKRMLSLSDIAKTTDFNSSIVSVGRTSFPNSFESSEEEEDDFSSVEPMLENRNGQIQNAKNDLIDINISSDSTESSNEDNKGSGEEQVLKKNKKNSSVRLAGDTLKKEANSRKRKVSGLAGLANDAKVAPSQAAKVNLTMKNTAIARKKKAIDSVSQKKTKNSSIPIFNGTVNNTPQGSLSDGAKNKRKSSEIAVPLTQPVKLSFESTEEDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9U3</accession>
    <name>A0AAD5U9U3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000061">
        <property type="protein sequence ID" value="KAJ3225445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9U3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051114">
        <property type="entry name" value="Mito_RNA_Proc_CCM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934:SF6">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN PET309, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="316"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="78380" checksum="AC6213E6647D99C5" modified="2024-05-29" version="1">MFQNILRHKHNRTRSQCISNLAISRCVNKQFNYPCFHLVQKCFLTSQLPSLRTHSEGPVKEKKSNYKQKSEDLKMDKTILLKHNINKFMYSINTMNLNEAISNYNDLKKNSTTASIFSCVNQTNFSKYLELLEDSYLKNKIASVNALNQFAEDFRPILQRKYLDQQTKNNIATLIRLLGTVGNVESAVQFFITFKSTSLSRRELLDLQIFQIMLIIFERHKMIRNAEIMFKEMVENANLVLDKLTFVLMIKCYASVADVNGAFKIFRYLTTQTNYGVNYGVFHSLISASKSLKNPSPSHSPQAILDIMRKYNFPPNERTYTMIMAIFVQRRQFVEAVNLFKKMKEDALTNPEATPQIATYNTVLNIYGTIGDIQHAKVIYKEICEKLKPNNVTFTILLKAFKKVNAFNAAKQLILEMIKKKIAVPSRDFNLVLSFKTNPVEYEKLYREFIQLGMIPDIYTVKILICSYVDKSDFEGVVKIYKESRQVYKITPDSAFFEEVLNRILRLTRKQYIISRVDTNTTTKNDLESVFKVLMYFEEEIMKISNFNLQLVFNLASIKNCLILTKLYLDQLNFVKKEDVLLHFLVNFKEMFLGEGIEGTDNHKVIIPNEATLKIILNELPKSEVGSKCSIIEKEILLLCYTMLGKHSVFLEPDLHTSVADRIMKLSEVKVSYCGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAA2</accession>
    <name>A0AAD5UAA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAA2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="73" mass="8382" checksum="0D87C9ABA1A3D497" modified="2024-05-29" version="1">MELASVEEEYNVRLDTNLDLLVSNFSYLLRASTLTYEQVDKLGQEITVKKNKFNVKQEKLLIDGTTANIVIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAH9</accession>
    <name>A0AAD5UAH9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000038">
        <property type="protein sequence ID" value="KAJ3226352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAH9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="4">
        <location>
            <begin position="47"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="343" mass="37533" checksum="FFC1E11ED61BA8CC" modified="2024-05-29" version="1">MITTLLRGQNKNFLFKDVKLINQIRFQSAYSGKNQYKQSRPALPTNTIIKFVPQQEAWILERMGKFHKILPPGLAIMVPVIDSIRYVKSLKETTVEIPAQSAITQDNVTLELDGVLYYKVIDPYKASYGISDSDFAVSQLAQTTMRAEIGQLTLDKTLSQRTQLNLNIVEAINVAAADWGIKCLRYEIRDIHPPDNVVASMHQMVSAERKKRAEILESEGARQSSINIAEGQKQSVILESEALKTKHLNQAAGEAGAIVLRAQATSQSIKEISDAISKAGLSGKDAVGLSVAEKYVDAFSLLAKKGNTVILPSNVGDISSMVSQSLAIFKGVSNTLDNGGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAP6</accession>
    <name>A0AAD5UAP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAP6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="525" mass="60735" checksum="DFD0D9CF9E698C32" modified="2024-05-29" version="1">MTRVDYRNLAKKFLLQAPQQTEQTTKNQPKLSSVQKTPEKLNFLKYLKFKCLDVNSTLEFYQSLGMAVDLNTTYVVEDSLQHENEVGTTKTIMVFSYWESSTNQLPNDGESSDQIYLFKPTVTNTENSHDFKLMFEYTDTKTVNKVPVTEEEDNLNENKKKFGFVEEKHNSEYLVIYVHFLSRLIKRIANKGFEIVVFPIDISETKIAIIKDPNGMEIRLMELNDTQLGETGPKKLWFARIGFYTIPTNCATDTCANYEKLFLPKSKPSDNHHKIDKNEKVDLNKPNVLGFRVVDSDDFIVGLTRTQFFWMGTEQRSQNFTICFVQKKDMSGAYISDDLNTPNLKLVAIGFQVGNIDSFVIKARNEKGTFHIDEGKFKIPGLGTFQRLQDRINRICVESFTPGLGLKTETQKEKQNKTAEKKLKENNKNKSQETKINVMAPRFPSAGVIEVKGRYWEKDDDEEDEEIEEEKEQEKKESKLSFNEKHKLPKLPKLKEDEKRKSTRVKMLQETLTSKDKLKSKSANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRC4</accession>
    <name>A0AAD5XRC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002126">
        <property type="protein sequence ID" value="KAJ3199385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRC4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="126" mass="14682" checksum="7B85C7E6C866D6B7" modified="2024-05-29" version="1" fragment="single">MFFEILDDKIELPYKKLKAVSSGPTVLIGVSGCGKTATCYHLCRTRFALYFDCYASNNMMYLLQKIAQIVPTEKSEETQWQFENKTRHYISCLLLSRLLVLDYLLSKDPLLCSFDWLKYQLSSRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSU1</accession>
    <name>A0AAD5XSU1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">REV3_1</name>
        <name evidence="8" type="ORF">HK099_000259</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010001050">
        <property type="protein sequence ID" value="KAJ3207509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSU1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="6">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="7">
        <location>
            <begin position="117"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3207509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="189" mass="22228" checksum="0540DE5C60855CEF" modified="2024-05-29" version="1" fragment="single">DPRAVPEYKERVPYVITYGTPKQRLIDVAVPPQELVSNPNLLLNGKYYIKKQLIPPLTRVFNLIGFDIEKIYEDMPKVNRAIKFYESGKAEKESKNEEEKKKKKKFTIDEFYDAKYCDKVAGMLNLTMKIRKYEESLEKCVKTCKLCSGYFDDFNIECDSVDCPVYFKREKSLKKYGFSLELKKIIEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSY7</accession>
    <name>A0AAD5XSY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Multidrug resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ABCB1_1</name>
        <name evidence="13" type="ORF">HK099_000178</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001027">
        <property type="protein sequence ID" value="KAJ3207855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000102">
        <property type="entry name" value="ABC multidrug transporter Mdr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000009">
        <property type="entry name" value="ABC transporter B family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000205">
        <property type="entry name" value="ABC transporter B family member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002283">
        <property type="entry name" value="p-GlycoProtein related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="723"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="770"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="847"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="874"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="950"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="69"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="393"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="727"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1048"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1036"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1036"/>
            <end position="1058"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3207855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1297" mass="141489" checksum="4F8B5D449CCFA0F9" modified="2024-05-29" version="1">MTKVQVDNNNLELKDIPSSQQEIKNSQDNNNNENSNKKDSKDKKPALPSIPFTTILFKYASPSDKFLIAIGFIFAAANGASMPLMTIIFGDVLDSFISYPYTKDVNALNNDVSLGCLYFVILGLVCWLAASLQMGCFMCTGENITKRIREEYLKAILRQDIGWFDKNETGELTSRLTADTALIQEGISDKVGLCIQSVCTFIAGFIMAFARGWQLALVLCAIFPLLGIAGFVMSRNMAKQSSGGQDAYAEAGAVAQQTLASIRTVTAFNGQEKELNKYDKCLVKAQGSGIKQGLFHGLNIGIVFFLMFGSYSLAFWYGSTLIVNGVMTGGTVLNVFFAIIIGAFSLGNAGPGISAMSVAKGAAFKIFSTIDRQSEIDSSSNLGEIPTTFTGDVEFKNIDFHYPSREDVPILKNFSLKVKTGQTVALVGSSGSGKSTIVKLLERYYNPIKGEVLLDGKDIKSLNVKWLRENLGFVGQEPVLFSTTIKQNLLYGLPTSMANLSKEEIDTKLKNALEQANAWNFISKLPNGIDTNVGEAGGTLSGGQKQRIAIARAILSNPKILLLDEATSALDTESERIVQAAIDKASVGRTTIVIAHRLSTVRTANLIVVMREGEIVEQGTHNELLKLAGVYKSLVDSQRLKSKNSLSDISEREGGVDADIVSPQMQEFKDEVLIKMEDKKVEKRVSIIKSLDKLEEQKKKEQEILKSRSVSFLRVFSYNKAEWYLFLIGGTAALINGAVMPLFSLIFSSILTVFGNVGNPDELRSGANFWAGMFLILAAGTFLGNFLQISIFTATGEKMTRRIRKQCFESLLKQEVGFFDDENNSVGILVTKLADDAGQIKGLTGQLIGSVFQTMSTMVVGLTIAFYHGWQLTLVIFCAMPVIAAAGFLQLRLLTSSGAKVKKAYDEAGQVACEVIMNIRTVLTLTKESEFLKQYYAAIELPHQNAIKGAVLSSFAFGFSQGSIFLIYALAFYYGSRIILWDIRGAEDVMKVMFSVIFTAMAAGQAANFAPNVAKAKLAAISVFDMVDRTSRIDPTTNIGNKPERSSVQGEASVNSGKFNYPTRPDTKVLQGLDVLANPGKVIALVGPSGCGKSTVIALLERFYDLQGGEAKVDNEKVESWEVKHLRSQMALVGQEPVLFNVSIKENILYGALEADTPDSKIEEVCKMANIHDFIVSLPDGYNTLVGEKGGKLSGGQKQRIAIARALIREPKILLLDEATSALDSESEKVVQQALDLASKGRTTLVIAHRLSTIQNADLIYVVNDGKVIESGKHFELLEKKGVYYELVNQQNLGKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT75</accession>
    <name>A0AAD5XT75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000906">
        <property type="protein sequence ID" value="KAJ3210123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT75"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052091">
        <property type="entry name" value="Beta-ala_Activ/Resist"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44394">
        <property type="entry name" value="BETA-ALANINE-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44394:SF1">
        <property type="entry name" value="BETA-ALANINE-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="Beta-prop_ACSF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrrolo-quinoline quinone repeat" evidence="2">
        <location>
            <begin position="413"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3210123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="760" mass="85871" checksum="D765A62FEB594D37" modified="2024-05-29" version="1">MEILIPLSSNGAVVLIDRSDLLQPDTFFNILVKTKINLLMMTPSLLKRFNSFQLHDILNGKTYIQDLILGGEQFPNSITVCRIRLWNIYGTTENSVWASLTRVDFQNNGRASIENVLDETTLKIFSPDVDKITSLTEEITNGDGQIWLGGKSRQCIVGDEVTPQDLRPTGDLASINELGIFYIGRTNNVIKKSGYRLCLEELSNHLHQFSGISNCVVLDISSKLVIFIDFINEKPLNVDLLSNYISSTLPFYVHPSELVVLDENFPITINGKIDKREIQKIYDNLQDSQIIQLDPSDLNKLRNTIILKHIYDIQMQDTEVFSKRLLTLILHKSINDLVDEIHDYLANSYAATTASSKSVIAEKEKANRLVKFGHAKEKSNVLDISTFSKGGRLITDDSNVKINYFNFVGKVYLKKCIDCSPLIVQYKYEAFEEAICFIGSHFGNFLCFKVEDGCPVIWEITLGDRIESSACFMFDKKYLIQNVCFGCYDKYIYFVSARSGEIVDKYLTGDIVKASPVFNKKEEVTYVGSYDENLYCFNLNGNLNWKKKLVGGIIGSVGLNEDCSKLWIGTLKGKVYCLSTDGQKILVTVDLKMPIFSSPVIVEEISNSVVVGCVDNFVYKISELGDILWKFDTEGPIFSSANILKKDIIIGSHSKKLFLLNLKNGKLLKKIKFDSEIYSIPYVIFDEYVIISTIGGSLKLIRIEEKEVEEKEKIEDSEEKLIEVEFSKECFSSGVVVSVGGKVYCVVGCRDNFSYCYELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT94</accession>
    <name>A0AAD5XT94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="18">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">HK099_008217</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 18">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 18">Membrane</location>
            <topology evidence="1 18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="18"/>
    <dbReference type="EMBL" id="JADGJW010000883">
        <property type="protein sequence ID" value="KAJ3210559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000087">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF174">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 17 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 18" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="974"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1010"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1063"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1124"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1151"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1201"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="21">
        <location>
            <begin position="56"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="20">
        <location>
            <begin position="206"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="22">
        <location>
            <begin position="947"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="22">
        <location>
            <begin position="1119"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1310"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1315"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="15">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="611"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="634"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="672"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="752"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="753"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="754"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="864"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="870"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="920"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="923"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="924"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="924"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAJ3210559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1362" mass="153979" checksum="910FEB2A21107DFF" modified="2024-05-29" version="1">MSVSPSGRKISVEPALRNQLHSNYDPPKPFFSKKIERCLPGFISKSASSINSYFSKNSNSNFINNKVKTARYSIIDFLPKQLFFQFSKFANLYFLFISILQYQPDWSPTGRYTTIIPLSIFVAISMVREAYDDVQRHKQDSSENNTLTKRLRIDGAIEKDFMASLARRSATLRRAKSEPITPSDTDVNEPFLEEENKTNFNNISLSWESIPWRKISVGDIIKVEDKEIIPADLILLKTDHEDGTCYIETANLDGETNLKQRSTLPATRDFLKSDFKLLKLKASIHGESPNGSLYNFEGYLEIDGQKHPLTSNQLLLRGSTLANSGHILGVATYTGEESKIRMNANSAVRSKSPVMEKITNKIVLLVFTSVLILAGVGTVSRVFWERAVLKGGSAPWYLKSQPTDWVATFFSFVILFNALIPISLYVTLELIKLAQIFFINKDLMMYCEKSQSPAEARTSSLNEDLGQVQYLFSDKTGTLTENVMIFRKISVSSLPFSFVSDEKSSLFSKADILTENYIKDLKKHTDQESDYLCGVEFLKAISLCHDCTMEKVKKDAPNSSIIYQASSPDDVALVSGARDMGCTFKSKVSSTVTIEFQGENQLYEVLDVIEFSSARKRMTVIYRYPDGTIKLLCKGADSIIIERLKSENTTEESKVFDDTMEHVQRFATEGLRTLLYSYKSLSQEDYDKWRTRYQEASVALNNRTALMEEVAEEIETNLTLLGATAIEDKLQAQVPETIHKLQRAGIRVWMLTGDKLETAINIGSTCQLIKEHSEVIVFKGLNVEDLGRHVKVASGDIKKFKSMESGGKHVVLVIDGITFGNMEKAHQKILKQHKSKNRKSKLLESVFTQFFTAAVTCNNVICCRFSPSQKSTVVLTVKELLNNSQDGVIGLFQVKKTMYYYMANLFSLRKVSGVTLAIGDGANDIPMLESAHVGIGITGREGLAASRASDYSIAQFRFLQPLLFVHGHYNYRRVALFTLGTFYKSVAFYVCQLFYQIWTGFSGTSLFESWTLSLYNILFSSLPVLAVGIFEKDLRIGTLLGVPEIYRSGQQNLLFNIPIFLRWMFQGLIHAGVAVILPVFVYNAAMFKDLLVGNFTSSRLIAGRKYIDEIFFSDMTGPYGDSSLISLGTISYTIVILVVTLKIGFVEAHNWTIFTAISAGCSIGVWWLYQFIYANLWPRLGEFGYDALGLFYTLQNIQLQIWSIALLGTTVSLVLFDLSYHSIKILWSRWRRYSQNLLRRDLEFDADNFKKTDAVYDFSSVSADKVSEHWQNDDFTYSIRWWQKWEKLHSKELKLEEENNWKQFGKLCPTEKNSKPNSNINNCSNKIGLESNSPNSNGNLHNSSNQSGEGINSAINIDETVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTS6</accession>
    <name>A0AAD5XTS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GDI1_3</name>
        <name evidence="3" type="ORF">HK099_007224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000684">
        <property type="protein sequence ID" value="KAJ3213700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3213700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="243" mass="27248" checksum="E4355ED097F3B3B9" modified="2024-05-29" version="1">MNETYDVIVLGTGLSQYLSLDGKKVLQIDENPYYGGESASLNLVQLTEKFKDANLDLKELNSKDWAVDLIPKFLLSNGEIVDMLHYSNIPRYVEFKQIDGTFILKNGSISKVPTTEVEALTSSLIDLAEKNRLKIFLEFIKSYVSEDVSTHQGVDLCSIKMRDLFEKFNLSKETQDIVGHSLALNQDDAYLDEIAKDTVNRISLYVTSVARFGKSPFIYPLYGLGELSQGFSRLSAVNGATFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTX0</accession>
    <name>A0AAD5XTX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GYP5</name>
        <name evidence="6" type="ORF">HK099_007129</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000668">
        <property type="protein sequence ID" value="KAJ3213876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTX0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.750:FF:000003">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000027">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000001">
        <property type="entry name" value="TBC1 domain family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="5">
        <location>
            <begin position="250"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="55"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="545"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3213876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="676" mass="78051" checksum="63729730DDE6341D" modified="2024-05-29" version="1" fragment="single">KFNLEFVLKLNLKNRKIEINFNYRMMSTAVEEPSSPWNENSTKIILNLTSSEEIKSSPTLEENKWNDETQIEKKDTNLDQNQDSDFSKEEDSINLSKDDSSDDLLLSELPRNKFPKSAKSVFERRSNNSVSSNLSFISSISDLAADYSPTDTNSVIDSPGNCSTVVEEETANLLLARIKSEKEVQKEETTNNGFDPFSFIKSSFLAVKESVVGQEKENDVDWDFWGKVVSDFDRVALKHSRTLTKKIQLGIPSALRGMVWLLLCKGKNPELEAVYTTLLTRSTTHEKLIQRDLSRTYPKVEYFQGNDGPGQEALFNVIKAYSLYDLEVGYCQGISFVVGALLMNMPEEEAFCALVQLMKQYRFRELYTSDMAGLQLRIYQFDNILKEHLPLIQKHLEKEGIQSNMYASQWFLTLFAYRFPLDVVFRIMDMVFAEGLETMFKIAIALLKKNKDYILSLDFESLLEYLKNGLFDVYISSDTITSTSNGLEKSPTQVASSPTNTEKLTTTNLISDASQIKLYKSTLVKLETEFLEQQKNDNDPELQEAKQLRSQNRVLAENFKKIEEAYELLNREHIILANDNLERKTLMEKQKEKLEELEEQVNSLKQILLDDRKKAENLVKDEMDLLMNKNFNLTKRNCELQDINLEQDDVIFNLKRKNFNLEQEKIELLKKINEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUT4</accession>
    <name>A0AAD5XUT4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005624</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANT/ATPSC lysine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000448">
        <property type="protein sequence ID" value="KAJ3217021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUT4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905706">
        <property type="term" value="P:regulation of mitochondrial ATP synthesis coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610:SF11">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="174" mass="19822" checksum="C98AC7CC48D38F35" modified="2024-05-29" version="1">MNETNRNSIDSENNPFPFSNEDFVGSSLNLAQSPPQTCIKVIDLLISYSSAEVDAAKRGIKSIGVDLDPRLIKECKELSKSLNLDHLTEFVLLDMFDFDLSNFTICSCYIYKKTLNDLHFKLNTRLALGGFTLATILYPFNKINPVFNDDIYKIFVYDQTSLVVNNQNKNKKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV96</accession>
    <name>A0AAD5XV96_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000370">
        <property type="protein sequence ID" value="KAJ3218666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV96"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="517" mass="60580" checksum="DB1C715BAF5D3B7E" modified="2024-05-29" version="1">MLTSLPELNDHSLKSTSDLKKNKTNFLPEGKIADETNEDEPDDELNDVVVDLKATLYENADFDVNKLNEMVSSEKCIKSNFVNAICNSPKQKFVRMGSKRKESKFPIKQLVIWPELWEKVRNYFGVKCIYWFRDSPLIGHWKNISNMKAWDYMIFEYIYIIKGKKINSLNNEFDPVNSEGWNDFILKPYIGQGCRFFRRDVRIWLSDNKSEISKIFKNVSKAVVPSEVLLILKQLLSFEQNYSNLHEAGFFERPSFDADLESEAERRLNLMKSFYNPEHEVWTDHESIQFNRTGIPRREKTVKRKSELSIEEERINKIQKTSSISSRENSISETDIDEEDIPEDDSGIDDEEDIPEDDSGIDDEEISTIHKEISTFHEEISLENSKYPNEIIELINQENSKIILMESRKYFGENISHSFWEKGDALKVNIYNKNGKPIAKNFNISKDPDFNFEQLLNILPLPKIPTEFNEKYFFFLLKKPSLHKQDLLELVFKDEDCCSAKLKMGDNLFIKREIKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW77</accession>
    <name>A0AAD5XW77_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001265">
        <property type="protein sequence ID" value="KAJ3204790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW77"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="102" mass="11449" checksum="12C3D2FE8519C1A9" modified="2024-05-29" version="1">MDAMVHTIGNGKQKFNVWYPAKNSGNWSSTLIEMAIDLVLDTRELEQDSFTVNLTEVGWDGVVAKEIICPESCPDVILLGTTQLANRLQKKVKKKNTYKFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWH3</accession>
    <name>A0AAD5XWH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000209">
        <property type="protein sequence ID" value="KAJ3221777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWH3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="3"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="239" mass="28063" checksum="CCFD115DFB652B07" modified="2024-05-29" version="1">MGVFPLLELPLEILERIGKIVLLEDIVSFINTCTKLHNLAVYRPFMELYHVTSSRKIQVIMKSPWKEIIHNTKIRWTPLTRTGTLAFMVQDKGFKFFYNNLKYFLDRIWIGSRPDDVEQFERDLSKISTNLINARDPLKFSDLKLLIKSDNTTPRKILFIESKRILWSELTQENLIELCKYLKEENIGGSAIILESVLTNLNFSIAKNNNNFDKFFVALDKIKCEENLRLIFEKKLSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWK8</accession>
    <name>A0AAD5XWK8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000662">
        <property type="protein sequence ID" value="KAJ3213948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWK8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR 157-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23112:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3213948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="247" mass="27996" checksum="09382C7E4E9EF698" modified="2024-05-29" version="1">MQIFHMAAICWQGCIATHCFIVTTRAATTNVQKLMKYYHIISWGFPLLMASIPFLVQISSNFKVLAYGPAGIWCFSALDWQRVFLMNIPVLVLFLYNVILYAIILKLCKYSGKSKASKGIDRIIVKTGLYILTFCFVWSGPSANRLQNLMYPGKPMFSLYFLHALTVASGGFFNALIYLYFLWKDQKSKFKDISLNKIMKKKKDVVTESSCDSALSSMNVSNFSAMQSTPSTGVESTFSKPNYTYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWU8</accession>
    <name>A0AAD5XWU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000591">
        <property type="protein sequence ID" value="KAJ3214789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWU8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="673" mass="75342" checksum="F89296EB4AE76577" modified="2024-05-29" version="1">MKDISKSLTDFQHIFEAENMKNSTKLNYTSKPNLKVDTTEGKATDLSSPNYMNYDENKIIIPETNQKLDFKCLEVEEIFQLLKKTCLNASQAARNLNDDGKFYKTLIEVKDSFLVRAKEIKSFRNNERDDNINDLNQRLFDLHRVCWNLNNKLVKISAQRSPLGQSTKILLNKKKLVAFANEIHEAWISLMLQLAMMLADKSTKDATDASVHVAQLAIATGSPDWKDISLDDAGKLYTQGDKFLFGYGFPQSYDLAYKRYQAAANAGFPEAFNMLGMMHENGLGQKRDMNLALQNYREAASKNCLDALNNLGRIYQNGLGCSVDYGTAQEYYTKAAEGGHLDAMVNIGYLLEHGLGSSANSEASFHWYNTAAEKGYAKAENAVGSCYYKGLVSLKKNPEEAVKWFRKSSLQGNSHAMNNLGICYEEGLGVSKDLGIAKQYYKESALLMHPSATNNYGYMLLLEHDYDEAIKNFHMSMHLGSAEGAFNLGNLYENGCYHYSELILSTDLDMAIKYYKIAAKKNHVQAQIRLGIIYLTGPQQIQSPEIALQYLTPAAEEGDNGDAQNLIGQMKELGLVGSNYQEQPGLGGSLNSLKSSNNTLFQPDYKSSKVWYQKALLKGHLGAMYNMGSLYEQGNGVERDIEKAALYFQMGAKGGHKESTLKIEEYKTLRILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXM3</accession>
    <name>A0AAD5XXM3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Tubulin polyglutamylase ttll1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TTLL1_2</name>
        <name evidence="11" type="ORF">HK099_007280</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tubulin polyglutamylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000696">
        <property type="protein sequence ID" value="KAJ3213584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXM3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF31">
        <property type="entry name" value="POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3213584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="97" mass="11756" checksum="FD9CF0E7D9444301" modified="2024-05-29" version="1" fragment="single">MEKKKEVKWMTDIDKSCLKANFEKRGWVEGTVDDWNFYWAGVGNYRTLMESQRLNENQIVNHFPNHSELTRKDLMVKNIKRYKKEIEKTNPTELKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXZ4</accession>
    <name>A0AAD5XXZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein bL21m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007737</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXZ4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="187" mass="21238" checksum="49EB30E4DF25128F" modified="2024-05-29" version="1">MLKLIKGSRLFSNSKSTSSIGDVIKNSIAERSGLNSSTSSIQKTINSKKTENISSGDTFYKLPAAAKDKWMSFSQEDQFYAIIQLKLKPYYIKKNDIIISSKLNDLKPGDKINLEHCSELGSKNFILTGKPLIDRNYFKIEAVVLENFKSDLLIKERRMRRGRNKIVINTNSHTALRISEISVNQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY47</accession>
    <name>A0AAD5XY47_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polysaccharide lyase 14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_004613</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000330">
        <property type="protein sequence ID" value="KAJ3219718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY47"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048958">
        <property type="entry name" value="Polysacc_lyase_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40124:SF1">
        <property type="entry name" value="DISAGGREGATASE RELATED REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21294">
        <property type="entry name" value="Polysacc_lyase_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042030588" description="Polysaccharide lyase 14 domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase 14" evidence="3">
        <location>
            <begin position="208"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3219718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="414" mass="45318" checksum="1B8C5CF8FD1E7598" modified="2024-05-29" version="1">MKFSFVAVVFFLILLSSSIPLPKKSGTVIVKSPISSNVDGFVVKELDSDDKTKATKTSKIKSPKETKTKKSSNEKTKDSKPTPTEVSKKKDDEKVEIPKKSKSKDTKQNDFAEVTAATITEKPTETSDVTTPSQDPSQEPAAETTAASKKSKSGEKQQEFTTSKPGSKSWKLPNFNGETDAYKALYGQHQTGTDPKWRSIVNDPLGGSDKVMRVEYGSGSFGSKSNGGQTFYAQPPVDWKNAKKVKFCYDIMFEKGFEFNSAGKVPGLWGGPAENCKDPSTCWSARFMWRHQGAGEIYPTIDLNKQPKGFCANPKQCLNGSGDQGISVGRGSFKFSCGSWLPICQVLRATSSNGEMKVYVNGDSNPVINWENLVYANSGFSGIQFGTFFGGGSDERSPKTQYSYFKNFSVDILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY76</accession>
    <name>A0AAD5XY76_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="8">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">UXS1</name>
        <name evidence="24" type="ORF">HK099_004461</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-xylose + CO2</text>
            <dbReference type="Rhea" id="RHEA:23916"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="EC" id="4.1.1.35"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
            <location evidence="3">Golgi stack membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010000315">
        <property type="protein sequence ID" value="KAJ3220127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY76"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05230">
        <property type="entry name" value="UGD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000150">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078:SF6">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="13" id="KW-0274">FAD</keyword>
    <keyword evidence="10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="18" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="20" id="KW-0456">Lyase</keyword>
    <keyword evidence="19 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="11 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15 22" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="23">
        <location>
            <begin position="73"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="24">
        <location>
            <position position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00051601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAJ3220127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="724" mass="82011" checksum="F6ED9FA8BBA78EA5" modified="2024-05-29" version="1" fragment="single">SSKKMQKLGRVPFSNFGQQKRLMRFEPLKNYDVKPEQYKIIYFIFAESAVIIGYDIYYVLYLHEPPIYELSTKEFRKAFLKEIVPVTNSTSLFRFHILTSSVENTPIPSHVLVKDDTCQVARAYTPIAFTRETIDLLVKKYDDGLVSKHIHNLKVGDKMEMLGPIWSFPYETNMADEIGMIAGGTGINPMYQLIKQILRDPLDNTKISLIYANRNEGEIVLKNELEILSRNRPDRLRVYYVLDEAPKNWEYGKGIISKKILKENLPTGARSLVLVCGPEPMVKYLAGRKVAANNQGAIDGLLKELEYTEQNALTINNLAFSNQIIMSEQPKKEKKSEIKLKYVGSDQYSSKVDLEILQSLYLEPSKSMVETDKGSTLTFTPTVAAYPAVKNLKQHEKKRILVTGGAGFVGSHLVDRLMLMGHEVIALDNLFTGNKRNIIHWVGHPNFEFVRHDVVDPFMVEVDQIYHLACPASPPHYQYNPVKTVKTSVMGTINMLGLAKRTKARFLLTSTSEIYGDPIPEQHPQVESYWGNVNPIGPRACYDEGKRVGETLTYAYAKQDNVDVRVARIFNTFGPRMNEFDGRVVSNFIIQALKGEDITVYGDGSQTRSFAYVHDLVDGLISLMNGNYTDPGFLSSLIILMSVIFLVNLGNPEEFAIQHFAEVIRDTVNKSVDIVNLPATTDDPQRRKPDITRAKQFLGWSPKFTVAQGVEDTVAYFRTRLESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYW0</accession>
    <name>A0AAD5XYW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002937</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 7"/>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYW0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000808">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.340">
        <property type="entry name" value="Nucleoplasmin core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="9">
        <location>
            <begin position="294"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="107"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="107"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="190"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="233"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="537" mass="59071" checksum="6E8AF3BB3BC9B15D" modified="2024-05-29" version="1">MLLATQLWALRLVPGKEYSHVLEESIVVKMASIASENPKTGRVQVLLTKNEEGVKTQFVLCNLIVNAHEQQTLDLVLSAGEEVTFSLKGASEVVDLVGNYVENAMDGDDDIFDQFDDSDANNEEGIEEDGEDDEEESDEDDEESEEEMDENEIKKILDQALKRKSSEETHSSKKAKLANGTAKQSPVDTPSKKAETKKSESPAAKKAEVSTKKEEKNSTKKTETPSKKANAAETKKKDTPIKDSESPVAQKEKEKKKTTPKEEVAKPAANKKTLPNGLIIEDILVGEGPKAKKGKKISCRYIGKLMNGKTFDSNTKGKPFSFKLGGGEVIKGWDLGFEGMSVGGTRKLTIPANLAYGTRGAPPDIPGNSILQFEATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNRNSFMNTTKWVDDVRAERGNDVIIVLVGNKTDLNEKRQVTTEDGEKKAKEFNVMFIETSAKAGYNVKALFRRIAQALPGMENTVTEQPTLIDVKLNPNANKADGSSCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ64</accession>
    <name>A0AAD5XZ64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Annexin A6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ANXA6</name>
        <name evidence="4" type="ORF">HK099_006296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000533">
        <property type="protein sequence ID" value="KAJ3215593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ64"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0041">Annexin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="591" mass="66723" checksum="ED05526EE128D2C9" modified="2024-05-29" version="1">MIMSQNPVESHFENYYSKRIGGEEEFQQQFTNTVEKKLSCCSLNTVFSSEEFAVQPVLQPLNNTSLLQTNYEYQPATVIIQTASTDIQALPEEAIILNEPITVSNVNTNTCSFEDGYISVPVIPNEQLNTQPPPYSPELAGSPSTQSVLFTNNPTAGCPSSLVYTSSSSFTDASHCQPSMVCSSNEFIENVEINPNVLLSTLQTNNGVIEDPIINVSNSNTLTPINTFSAVNSNHNLTSELQIVSLEAPSYPESTHKFIGEDIPTYESSVAGNYDKHHHNNNFESDMEDLLRCFKGIAANEYTLIKIIGKRPISHLNLLNEKFQGKNGESLLLCIKQTTDHDMFEVCKAYLCDPYDYDSSCIKDSLRGMIGVDLESLFEILSGRTNLEMEQICTFYKKKTNCCLRKAISSKVSAKLAKFFDILLTTKRKEEEIITPEKVEFLTISLQNYVKEKKLTKILTVFCTNSVKVLQLTLQNYKIKEKRNFKDSFKKKFTVFNSLGDFEKGILYLVSSLEDLHLFFAEEINNSLDGIGAKEFKLIRLLVRITKLGKLEDIKHLYKIKFGRSIADKISRELKKNNFQKMLLACLDRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ66</accession>
    <name>A0AAD5XZ66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ66"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="171" mass="19240" checksum="0A67A3EC16956215" modified="2024-05-29" version="1">MKFTTEIVALLLSGVPPFIESIVIIITKRRVDIVSSVVLFCTLVGVVVTVATKNPLLLLVKDSCLTVGNNKVSRSLINFQTTKEDLEKLDKEWLLPGVQRETKVICLVWGIGLIFESILRTLLNLFSKIELKILVNINIAFPPVFVALLGLWTYLYILYLEKKNPIDVITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ72</accession>
    <name>A0AAD5XZ72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5'-3' exoribonuclease 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">XRN2</name>
        <name evidence="20" type="ORF">HK099_002667</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Possesses 5'-&gt;3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Interacts with RAI1; the interaction is direct, stabilizes RAT1 protein structure and may stimulate its exoribonuclease activity. The interaction also stimulates RAI1 pyrophosphohydrolase activity, probably by recruiting it to mRNA substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ72"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1050:FF:000002">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000003">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000005">
        <property type="entry name" value="5'-3' exoribonuclease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017151">
        <property type="entry name" value="Xrn2/3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF41">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037239">
        <property type="entry name" value="Exonuclease_Xrn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="16" id="KW-0862">Zinc</keyword>
    <keyword evidence="16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="19">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="886"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="938"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1010"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1069"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="519"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="967"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1069"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1134"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00046943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAJ3227302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1155" mass="133882" checksum="A9391AE468894B87" modified="2024-05-29" version="1" fragment="single">MGIPAFFRWITVKYPKLTTQAEEENNTDINNVKIPVDATKPNPNGVEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMYKEIFLYIDRIFDIIRPRNLVYMAIDGVAPRAKMNQQRSRRFRAAQEAQILIEEQEKIRKDLMERNIVGEGEEKKEHFDSNCITPGTPFMTRLAIALRYYIAEKLNSNTAWSNIKVILSDASVPGEGEHKIMDYIRRTRNQPEYNPNTSHVLYGLDADLIMLAIATHEPHFYILREDVMFKNAGNTGCFICGQPGHLAAACKGTPVDQTKTKTVLPAKPYIIFHVAILREYLEMELAFNHPAVQWDLERALDDWVMLCFFVGNDFLPHLPSLDIKEGAIDKLVELWKKHVIEQQGYLTNSGDIDLKKVKGLMMDLGVLEDQIFIERRKGDERRREARRRRRAEAKKSEEMKNLPKVHPSEVFDLIPSYPVNMSAQQRQETNLKAISDKRSGVEWTPDDVRNKNAALLLKESFKKNISSTTSVNLAKSEITEQVIGVKRTIENVKLEDRTDLVEEAAESVEKEETEDAEKIEEEEDEEEIEEIESGIVDPILALNIPEEVKKVVSKKMAQKDIMENDSEEEPEDNVKLWESGWKQRYYNDKFQTEADNEEFKRKIVTAYVEGFCWVLKYYYQGVQSWTWYFPFHYSPFASDFDFIDELTITFDLGKPFNPYEQLMGVLPALSRKHVPEPFQDLMLNENSPIIDFYPEKFPIDLNGKKYAWQGVALLPFIDEKRLVEEMKPYYSQLTAEQQKECMIGSEYLWLGKQHEDFEEICSFYGKKQMLKDEDNICKLPGTDVLGSCKLDAEVCLPASTFYSPLEDFSDIFDNCSISVIYLMPSYEPGFLFPSKTLSQVKFPRKMLDSVDYEFVRSGGGSVRGNRGRGGRGGRGDSRGINGASGRFIRHGIGADNDAEYYERQLDTPAYFNNHPQQQGGRHLPHHRDKKGRYEESHISHSQQFTSYRGSYRGNTRSQRGGSSSYNHANSHNTQYQYRSEQTFQYQQRPAHTTRQPHHHTPRVGDFQYQPDQRYQQRPAFQPSQYQQPAYQQTSYQQPIYQQPPQFQPHHQRPPYQRPQYQQPPNQQQFSPSYQQPRGGYNQRQNVHPNINHRYNAYPPRGRGRGNYNSRENSSHNGQISGGFVPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZA3</accession>
    <name>A0AAD5XZA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_006094</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000503">
        <property type="protein sequence ID" value="KAJ3216024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZA3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000048">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="C2" evidence="12">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="146"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="14">
        <location>
            <begin position="407"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="488"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3216024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="509" mass="57363" checksum="89392CE23B8CBAF9" modified="2024-05-29" version="1">MSQILGKLFVKIVDAKNLQCTSNAPKPYCVVEFEKSEFVTREPIDLTHDVNQNNEVTYASVWKHDANFDVSRKGSELTISIWDRAINNSDPSLSFIGMIKVRPPTINGKLYDNRFKLTPADRVKGDIRVQLMFQTVTSSSLSVDDFVFLKLLGKGSFGKVLQVRKKDTGRIYAMKILVKRDIVERQEIQHTISERNVLVQASSPFLVSLKFSFQTPEKLYLVLDYINGGELFFHLQKESSFTISRAKFYTQELIAAISHLHLNNIVYRDLKPENILLDSTGHICLVDFGLSKENIKFDDKTHTFAGTAEYLAPEVLAGQGYNKAVDWWALGILFYEMTTGLPPFYSENTNLMYNRILTSPLTFPDNNPDFTDAAKSLCLGLLERDPRRRLGGGIEDADEIKRHVFFDGVDWEKVNSKRYTPPFKPHVESSEDTRNISPEFTNTMPVDTPSQDAPISETLQKNFEGFSYIGNQTYSAESFSRSQFGSYGGSLGGGNGHGDGSYGGSPMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZD0</accession>
    <name>A0AAD5XZD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_000794</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZD0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17782">
        <property type="entry name" value="CBS_pair_MUG70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051462">
        <property type="entry name" value="CBS_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108:SF26">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN DDB_G0289609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="619"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="77"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="144"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="337"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="6">
        <location>
            <begin position="505"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="441"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="648" mass="71212" checksum="95FE9AECF278E58D" modified="2024-05-29" version="1">MLANSSQLSSRRSTTSIPRPSETLTSGEAARSRNKRRDDAIRRKVEQELSRKKPARKTSSMTLQAKRNALKGTVASLKPNPAITVLESARIANVAQLMAAKRSDAVLVVNEEGQLSGILTDKDICFRVVAAGLDSRTTCVAQVMTPNPIFVFDKGSRTEALSIMTERNFRHLPVISEVAVDEESEVNSEGEGSGVGTNVVGLLDITKCVFDRLDDLEKKVNEDENIIKALETLERRGGGSVVSAGSTPSFGCPDVGSVISSIHDGLDILCEVSVKASVRDAAKVMKERHHTAVLVLNHSTDGPEFDKLGGIFTTKDVVLRVIAAGLDPATTSVIRVMTPHPDSVTVNTTILDALKKLHIGHYLHLPVVSGTTPVGLLDVQQLTMAMLNYLISKDVSNNQESGPMWNKFWNSTFAPHTNSIGNSHSQMDDFSDNLSISSAGGNSVDYGNSTKRQSHHSRSNSQRSELRSLTHHGKTVVSSPQQQNLSTIESEIVNNSFVMEEKNLSYPFKIKDLINDTKFWITSTFDDYELLLNLIKEKLNGKSNSSIFRLTYEDDEGDLVLIECDRDLREAVNVSKRENTKRVQIYLDFVDSAMEKKKDYSNNAISKLSNDNNSQVLQFLYNAPLPVNVALSAGIIVIAGWVFHRLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y012</accession>
    <name>A0AAD5Y012_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_000481</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000111">
        <property type="protein sequence ID" value="KAJ3223941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y012"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="265"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="413"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3223941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="58370" checksum="307322C052F42704" modified="2024-05-29" version="1">MYITLLLIHKCCIDEDSRTLSLSSVCENRQSICVRNKITRATFYNWRKQWDESGIVKPLKKTGPKLILDKESKQELIEFFNKYPTATNEDGSIHVSNKIKPRTMSVSDEPENYLDERILQETKDYLDIIKNIPNETRVYMDESFVYDNEAPRYGRSISGQRKSRPRKRHGKRWTFYLALRLNGISRKFLDYVRNTLVPNLQEGELVIWDRLGKAGRCKNPKKQHYNPEAKALIEAKEQGLYFYHHKERTLKTNIRISYTLSDAGKEKRARTDSGAIAGLSVDILLFPLDTIKTRLQSQFGNFSTKSLYNGLQATVLGSAPSAAMFFLTYDQSKKLIFNNNETPLSHVVSSSLAEFNACVYKNLKDAVIDVKNKKEFYRGFYMTLFRDIPFSVLQFCLWEDLKKSYSKYKLRKIKPWESAICGSLAGAFAAFSTTPLDVVKTRIMLEKKNCKEYNSIFSTIKRIHSKEGMGAFFKGVGPRVLWIGVGGFIFLGTYEKVKKTLEDISSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0B9</accession>
    <name>A0AAD5Y0B9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_003354</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000220">
        <property type="protein sequence ID" value="KAJ3221594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="14">
        <location>
            <begin position="1333"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="620"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="723"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="630"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="729"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3221594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1403" mass="159652" checksum="C0CD026E57A6A1AE" modified="2024-05-29" version="1">MTDRLQFKYNNDGLQQGLESEERYNNGYSKSHSRVPSFDDIDAYIGGIVPLTDDPTMPTLTFRVLLIGTFWAIMLSFLNTFFLFRTNPFTVDTSVAILLAFPMGKILEKVLPSGVLNPGPFSIKEHVLIMVIASAGSATPYGIENVVTQKHSLYMGNTGITFLHSLGWLLSTQFIGFGIAGLLRRFLVKPKAIFWPGSLAYISLFTTLHKPDLPLGKWTMTRMKFFWLVFAAIYIYTWIPQFLAPVLQFISIFCIVGGGSKVLSFLASGDPNSKSGVGLFAFALDWYYVPPMSIQSPFIYSLNYFAGSAFFFWIVIPALYYNNFFRSDKSVVNHAAGGSRTLNTPELYGRNGTKIFPQSLFNTTTFDLNEKLYSEVQPIYISEMFAINYFSSFAALTAALAHIGLWYSRQISSQLKSAFRQVDNEEDNDIHNELMKAYPEVPDYAYLTFLAVVFTLFAVVTQYTPFEMPIWGVFLGFAITIFFLLPIGIIQGVTGTQIGLNVITEMIIGFIIPGKTVAVMCFKSYSYNNAIQALSLIADLKIGHYMKIAPRAMVFAQLYGAFIGCFVTLGTTWWILTAKVWMDSIGVHPEWNPYSGFGVFFNAGALWNLFEGMKKKKKKKKVVEEEEPQQEEKIQHEEIQHEEDQRVAEEEKVAVEEDPDAMFADLKKKKKKKKKDFDLEQPTEESENTEQLTEDFGALLAGKKKKKKSRQNVDDFEALLKADGDEVQQENNQENYNSVNQNVDPWIGSNRDYTYQELLRRVFNIITESNPDRKDIGAYRIAPPSIHREGTKKTMFANLVDICKKMRRQPDHLIQYLFAELGTSGSIDGAERLIIKGRFQQKQIENVLKRYIVEYVTCKTCKSGETTLTKENRLFFLQCESCGSTRTVSAIKAGFKATTKDSRKGCRKWFDNVELFLCEKRKLKESGGFSPAPLLRALFLWNGYGLGLKRKEKEKNISGFASPKENILFVQNKGFSFSAANPKKFIEGYLLLPGLRSSNLNFLKKIFNEVHSPNSSVASKSANGNSFNNNTIYPLLTTKTVFDSDASLLTNADLHSPITVLAKDLGSNLKVLEISPVKTPVKWLLQELKTNSSPLIKEDRITPGKVGIPFWESTPMKISPLGFKDNLFSDQRELTCQLSAEESDEIIVMEKEFNWEVDKKSCFLSKSFGLGHWNNRKFNHEVENVFLSKPDKKLVNPNFIQKKLPEMQVLKRPVLFNAQKPAHQQHLHVKKKLQRSFSFNDSNFPNKARKNMDGVFKKTDRIFLDDNEEECSSIKYDLENLEIAEIDKKIVVNVKELVDEKTGVPYFLGKDTFKRITPKTLDKILNGEIASIPNEKLKIIDCRFPYEYEGGHVKGALNLNTFESLRRIFETNRDGYNDKALDENSFFVFHCEYSLQRAPDMYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y166</accession>
    <name>A0AAD5Y166_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NEDD8-conjugating enzyme UBC12</fullName>
            <ecNumber evidence="7">2.3.2.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NEDD8-conjugating enzyme Ubc12</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">RUB1-conjugating enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ubiquitin carrier protein 12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">UBC12</name>
        <name evidence="16" type="ORF">HK099_001580</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.34" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000146">
        <property type="protein sequence ID" value="KAJ3223053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y166"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061654">
        <property type="term" value="F:NEDD8 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000005">
        <property type="entry name" value="NEDD8-conjugating enzyme Ubc12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="15">
        <location>
            <begin position="21"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="12">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3223053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="177" mass="19889" checksum="A38A895028DBF1AB" modified="2024-05-29" version="1">MSLKKKQGGAASSGNSKKQSAAEIRLQKDVADLSGLPKTMVMDFPDPNDFFNFFLRVTPDEGFYRGGTFKFSFKINTNYPHDPPKVLCTQKIYHPNIDLEGNVCLNILREDWKPVLNINSVLVGLQYLFLEPNADDPLNKDAAEVLRKQRNVFESNVNKSMRGGTINGVVFENVFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1M5</accession>
    <name>A0AAD5Y1M5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001936</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000160">
        <property type="protein sequence ID" value="KAJ3222768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1M5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="29689" checksum="9C35078963B4D74F" modified="2024-05-29" version="1">MYCSKTKTQGRIPDPCRAHSATFLGHKMYVFGGGDGSTYYNTLYMLDTQNFSWEKLEVQGTTPGPRRAHTSWSYNGNVYIYAGGDGVKALDDLYMLKLDEGDSLICWIKIKTMGKSPRPRGYHTSNLVDDKLVVLGGSDGHECFSDIHVLDLKTFTWTQSIPNRQIPRLSHSSTIVGSYLFVLCGHDGNNYSNQVLLLNLKNFTWETKKILGNFPKQRGYHSAILFDSRIFLFGGYDGSQVFDDFWALNLTSSAYLPLVKFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUI6</accession>
    <name>A0AAD5TUI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001343">
        <property type="protein sequence ID" value="KAJ3204083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUI6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF24">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="1">
        <location>
            <begin position="142"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="361" mass="39938" checksum="852B536AD35145A3" modified="2024-05-29" version="1" fragment="single">SILSSICLSTPLENKFTPAEFEIRKKVYKDYLPNASEADINRLATIENPTSAQIYAVSGVTDKFVTTSNNSRTISASSAVVQNLNQMQLYSGAAYCLFGLNNWSCNTRCTKTPNTIFVEKFDTLKEDTTGFIVYNTALKAIIISFRGTLSIRSAIIDLNLEQVPLESAPASEGVKVHKGFQAGYKVVQNLIRSNVGKLLQSYPDSHIRLTGHSLGGAMATVAALDLATYFPNQASKIQIYTYGQPRVGNPAFSTRVNKLFGDRIFRVTHETDLVTHLPSVNLNGVGAWEHHRREYWIDFNKQTKTCSSTVNEDKSCSAGQRDFADLNTLAKMLSLLTRFQTAGDLIDHLVGYYDVPFGPFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVH6</accession>
    <name>A0AAD5TVH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001506">
        <property type="protein sequence ID" value="KAJ3202891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVH6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="43093" checksum="733B6B5713E5AABA" modified="2024-05-29" version="1" fragment="single">IPNNIHPDNPSVCLITKDPQSEYKELILGNKDFPYIKKVQGVGKLGKKFSSPQEKRQLCDEYDLFLADERILPMLPKILGKKFFETKKVPVAVNIKNLKNLKEELDNAFNCTLLHINTGTLISVKIGLSSHTQEQVLENILKSIDQILKKIPFGIENIHSIALKTSTSPSLPIWTSSFEPLSEVEQKIKLENELKEKKELERKLKKSEKKNQNKVTENSVEQVSIETKKEEVEVEATDSKKRKLPDAQEKEETESKKVKKVTVIQEKNATKQVINEEKKIQVKKVEEEKKKIGEKKNQTTTITENKEKSEIIVQKPKKKKSNKKNKSTYVFSYPVWPAKTNGLVPPSSQTTRTELREYSVAWGYGSWHSFHVVYPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVP9</accession>
    <name>A0AAD5TVP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001380">
        <property type="protein sequence ID" value="KAJ3203792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVP9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042092912" evidence="2">
        <location>
            <begin position="21"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3203792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="117" mass="12128" checksum="ABB124CAE985766E" modified="2024-05-29" version="1">MRFTKFYLLIVLSIIAFSFAAKTTGADGVETKIRPNGGGETNSSGPKHTKDPKPVETTTDAVETNDIASTSVPASTTTPAPIPTSEATQPVGESQANAANKLVFGAGVAAAIYWLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVQ2</accession>
    <name>A0AAD5TVQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001988">
        <property type="protein sequence ID" value="KAJ3200018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVQ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="199" mass="22995" checksum="86A0FC8D21F1687B" modified="2024-05-29" version="1" fragment="single">CLIFLKFILTEKKDLESKVKNNLISLIKVYELILNSSTADNFKKSKLSASIPGGDTLLKKFQNYKENLCDYNHLDSQLTEIQLNKRKFVIKEEPKETINILNPNKKFKFQLVKDFQPSPIGTFSNTLNLSFEYDGDFWNKFGGPPKFDFDLSKVPNDDEILTNTINLEDDPDSVNKTFSNIDDYTNLDIINVKKNIRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVT9</accession>
    <name>A0AAD5TVT9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Asparagine synthetase domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ASNSD1_2</name>
        <name evidence="6" type="ORF">HK099_007965</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000826">
        <property type="protein sequence ID" value="KAJ3211575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVT9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051857">
        <property type="entry name" value="Asn_synthetase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparagine synthetase" evidence="5">
        <location>
            <begin position="211"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3211575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="331" mass="36897" checksum="D86D276BC610E845" modified="2024-05-29" version="1">MPHHPRLGILFSGGLDCMSLAAIANSYIPEGEPIDLFNVAFENPRALKGIAVTLKNSQQQKKKKTKLDKKLKYLAKQAGNIPINPNSITEVTEEYQFNIYDVPDRVTARQGLQELKTRFPQRPWQLVEIDVPYTEAVESKKKVLELASPSASVMDLSIAIAFWFAAKGVGRKISITGDVTEMYTSPVKVLFSGLGADEQLGGYRRHRGSYESNGWQGLVDELQLDVDRIATRNLGRDDRVISDHAKEVRFPFLDEKVIDFLSSLPCFVKSNPTVKEGLGDKILLRSLALDDRLGPLTLTAKEPKRAIQFGARTAKMHDKKEKGDDLADNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW69</accession>
    <name>A0AAD5TW69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="13">TC-AMP synthase</shortName>
            <ecNumber evidence="3 13">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_008141</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="3 13"/>
    <dbReference type="EMBL" id="JADGJW010000864">
        <property type="protein sequence ID" value="KAJ3210967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW69"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.870.10:FF:000009">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010923">
        <property type="entry name" value="T(6)A37_SUA5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050156">
        <property type="entry name" value="TC-AMP_synthase_SUA5"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00057">
        <property type="entry name" value="L-threonylcarbamoyladenylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF16">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="Sua5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004930">
        <property type="entry name" value="Tln_factor_SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="16">
        <location>
            <begin position="18"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR004930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR004930-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3210967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="390" mass="43708" checksum="DC1F8239BD106C74" modified="2024-05-29" version="1">MILKFENKEEPLNCINDRKILEAAAKLLRNDNVVAFPTETVYGLAANALSENSVLKIFKVKGRPSDNPLIVHISSFKMLCDLFPSTDSKIIPNIPRIYMNALKKFWPGPLTILLPKPSTIPYIVTANHDLPANPIARALIDVCNFPLAAPSANKSGRPSPTKAEHVFSDLGSEIDLILDGGSCETGVESTVLDGTANPPTILRPGGITWEMLKEVEGFENVKIYQKSNTNVHENFELNPTTPGMKYRHYTPDAKVIVFLVNDYTTESNLKLFNLIQEEIKKITENITNDEEKVDFIKNKIGIMARGNRNYQETFNDINIYRLELEQEGSTSDCENYCNQLKTIAKNIFNGLREMESLKMDYILVEGVVEENEGVAIMNRLKKAASKLVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWX1</accession>
    <name>A0AAD5TWX1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000722">
        <property type="protein sequence ID" value="KAJ3213330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWX1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="36308" checksum="98819A52B9C43E07" modified="2024-05-29" version="1">MLTDECIYKGEIKGQKENTNESTLKKFNFCKNEKKLNILNYLPTEIVVQIFNDFLKTKGSRKNIITLTKVSKSFRRIALKILNSQYKLGILELFQPVSDSNSNRYEKFCKKKLRFIETIFSSYERLTFRFAGYNYEKNMFEFIPFSKDRCFVVKNDTSDVVFGRDEESEVPKEEKNEFLIKQSSLISPTSPPLSLKVGNLNDFDFSFKATLKKAVGKVRPGVRVEEYAKEQNYYSLPIQLTQSNIFNENGRNILDFNGIKLVVNTEYDKKGQVNVEVENVYTSVEIFELNVNKVKSEYHTIEPFRIEIGGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXF8</accession>
    <name>A0AAD5TXF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001920">
        <property type="protein sequence ID" value="KAJ3200366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXF8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="147" mass="15964" checksum="D9145F137E8E0AE3" modified="2024-05-29" version="1" fragment="single">LNIILSTFIGIKFGQEIEKSDKDVESGSNNSGGDSSSSDEGDSFVSDADDKRDIERKLKEELGLSPRKKKSNTKLFEEKSTGEQPNNVPNTETEMEVSTNQSLETSNDSLSSSPSSSSVASQNLGLNVSRRCLDCKKTNLEKLKLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXG9</accession>
    <name>A0AAD5TXG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2 W</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">UBE2W</name>
        <name evidence="3" type="ORF">HK099_000261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001051">
        <property type="protein sequence ID" value="KAJ3207492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXG9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23808">
        <property type="entry name" value="UBCc_UBE2W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="4"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3207492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="21531" checksum="C91D2BE5B8B1F66A" modified="2024-05-29" version="1">MSSISLKRLNKELRQMQSNPPQGLELEIAEDISLWKIKVFGAKSTIYEGETFKLLVTFVENIPIHPHIYSNGHICLSILYDHWSPALTISSICLSILSMLSSCQKKERPPDNNIYIMTAGKSPKKTVWAFHAAHHPHFTNKTDLQNVTENTVNNNTNVASNIPPPPSSGAFSQQTSASLVVVSTFLSAIYYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXI7</accession>
    <name>A0AAD5TXI7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000898">
        <property type="protein sequence ID" value="KAJ3210294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXI7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849">
        <property type="entry name" value="LEUCINE RICH REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3210294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="337" mass="39596" checksum="8696134BD6FF5138" modified="2024-05-29" version="1">MVVLTREQVFSKIKAYRAHQSLQLNQIETLNLWGQNITDISILSQCKNLKVLSLAVNELQSLRPLCEVDLLEELYLRNNLIDDFVQIGHLENLENLRILTLSENPITAYDSYRSIVISILPKLTKLDDVEITEDERYESRIAFPNYHIESDFNDNNDNFFFEDVEQLNQYGDNYAFRSEEFPVNKITSNKIPDVTNFKFPPEEGELLLEEDWKDRNFNKKKKNTVSYRHKLMNDAENALHPEYFYVNANESENVKNYNEKENLLPDRLENLKLSENYKMMDTMKMQHKQNSIKEIDLQANKEYSTSNYPYTPISNSDTSSKINNVSPLKSFTFNVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY14</accession>
    <name>A0AAD5TY14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c oxidase subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MYO22_2</name>
        <name evidence="7" type="ORF">HK099_006002</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000496">
        <property type="protein sequence ID" value="KAJ3216130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053086">
        <property type="entry name" value="RhoGEF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45834:SF3">
        <property type="entry name" value="RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45834">
        <property type="entry name" value="RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="131"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="235"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="DH" evidence="6">
        <location>
            <begin position="695"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="374"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="425"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="548"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1027"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1180"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1278"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1397"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1630"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1717"/>
            <end position="1930"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1973"/>
            <end position="2007"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2129"/>
            <end position="2237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2273"/>
            <end position="2328"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2441"/>
            <end position="2482"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2588"/>
            <end position="2615"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2669"/>
            <end position="2794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="374"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="441"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2937" mass="336906" checksum="7780CB4D4E01DEC5" modified="2024-05-29" version="1">MSMSDSMSRRSSIKKTLDEINKFSAKNLLASLSKPTTVANNSLGGHSLGNLKKSNSQIEVNKLEKPCLLKKSNSNMDVSQISKKVNQEDLISSFSLNTTTNKKKKSDEKNKIDNSNKNCSEKIIQDGTLLGIGVSLRVVKENVANFEGELNLEQGDIVELSKVPITKSQLMWEGINRSWGERNGQRGLFPGKCVELEVYDLNPVGTESVYNTNSSLLVESIPSSESLNTIKKPVPLGTQVVVVQDYTKQKADEVDLNIGDVVVVLESPEGGWWRGIKNVGDKNPASGWFPANFVNIVRQPEKKPADQESLKEEESRVNSRKTWYKRLADLTHKSSKKGRKRAESAPSTKTISVIHQNHDSDRPESLLDSVAESNTSINQSKITKSKSSINEFQRRTSSPSISNESLSSILPTTEIVNNIITSRQQSHKRSISAPPGITFDATSHLSTATSSTSSQRHSRQSSRSNSMNNPAPPPTKNTKEADGNDWKKDSLLAAEDEEFRFLLTSEPENSSVNNILPSINLEPPEIGKETLAVNSNNVLPSIILEPPETKKESSVNIEESKPKEDVQSSILTTEIHDDSKSTSREKELELEKKEENLSITPSEDRKKIIRRSLSLNVSPTSGAFEIEGSMPENDIIALNRRSSNLNSTKASSIPLNPENSDKQIILPKRKLTIVSANYSGPDSKGIEKLSTKEQKRQTTILELIQTERDYVRDIKMVVEVFLKPITEKKLLAPKHIDEIFNNLETILLMNKEFLKTLEDRLSESPVISNIGELFLKAADKFIPYTIYCSHQAYSISKLQSFTKNKSDFRLFLEESYKGQQTRGLDLGSYLIKPVQRLCKYPLLLKEILKSTEETATDYPDLKLALEKVQAIVNLVNESARQSEGNGMKKIIDIQNSFTEKVNFVTSSRCLVREDIFFLQIGESKKPRKLFLFNDLIIVARKDWRDKLHLIEKATFRQCGISDVQEDSFEGHVSKHLFEIEIGEEKDASERTRYLFSCGSKALKQLWLDSYKNLSQLAVESKHLKDMKTESNYNSDSDDEEEVKKKRKADKLEIKNLREKLEKAEQKIANITKDLNLVQKAKSEQQIQIIKSDETILSNLATINKLEISQKEALLKIAELSTENQSLVEKARGFAADVNRLNNIITSNANKEKKNDAEKKAQIEVLDNTVANCNLETKKLKLEAIENQKKYDTLLNELENQKKLDLKSLEEKQAFTNKILELECQINSKNSEVSNLKANFQENLKLVTEKLCKSTKSLEEAESQQFKLTQAADILKKTIFKAQTQLQENESVIARLNENLSNAKLVAEKSDAIIQQKNVELKKLEFELAKNETNNLNLNELKSFFEKTVQLNQEKEKNNSQDLKIVELKEKILKDSTDFDKFKQEFEISEKLKIAGLKKEFSEELQTVKNQLQDSSEKFKEKLHEVEMQNQKLKSDLGRSDEILIEKENKIKDLEKQIEKLSRSFEDLKQKSMHIHEKQKLAIQVLNQKLEEERREKDTVTASLQKSHLIAVSEKDKNKVELERLKEEKEQLQNHYEMLKEELQSVKSFKDNEIQNLFKVITDFKDQFKCMEDSKAELTASKDLQNKTIAELNEKIKLNEILNKEKAERILILENELSKTSGTLESNKAFKELLEKTIQEKNDTLKEKERQCNELLQKLSAATESLVLKSEDAVKVKHSLNEKSKEFSDLKILFDNQEAVIKGIISELQGDKQELYRLSTLEKVLQEKNEEVVESSKKLKNAELGFKETEGEFRQEVKRLRAELKIVEECYDEYKKKVEAEKKNIVVAQQSKKTIELAATILEKDADIADLSKTVKEKNDIIKNNEAEIEKLKTQSNQTSSKLTTVISILQSNFKTLEDVNVNKDLKLSRLESELEKTTKQMNDDKSLLEKKVDLCNSESEKIIMNLKEIILKTTTEVEKANNEVEFQKRKCLDYCEKIKKFEKELNKKHNLITNQDESIKSLKNSIASMELFLKEKETKISEKIRENEVLVRDLHIAKNQLTEAEKSHSNLTIKFDDYKLIAGESQSKFEIMISKLKNVIKQKDEIISSTTKKTEELIKENEKKLSEQFELLHNEASQNKVEAKVLCDKLMEKEIKLVRVEIENEYLMKENSKGTNALNDFTQTANKKIDCDNMKLKESEIEIKNLQALVLELKENMQRVEKSSLEIERLNTKLTNLEIENKNLEMLSTEKQQNNNQLLQQLEEKDATLLTKLNEKNSEIETLKEKYQQTIDEVSHKLFESQKSLTDINHKLDLERDATKERNDVIFTKDKEIYKLRKELEAYENNVQEMVKSLEQKKSLIILLKREKEEIIISLQKLKVEFQGLETEKDLLFADNVKLKNQKQKFKEFLTQSAEENSNVLAEKKGIIKKLKRDIAQCSDSNIRATEALKLRDQKIVDLNQRLGLKTHELTKYVEKIGSLQIELDGLRVLKLESQQQMNKITEMSGKLEVLKEKLSSSNKQISELKLVLKKLEVEEKKATDSNFDLQLKLACLENEAGNLCSKLKESSLLEHQSTATKKELESLIFAKNTLNENFLNVSVLCEKRLKIISNLVKMINEISNLVLKRSLLDSENLAGQELSTDNEFILFLDLKEKLNNLLSDKKKLEHELDVQKSNFLELTYLSKVDLENIELLTSKIERSESNSNEKLKIKFAEVLKLKKELQLANNCLQTFKTENENFRKDLVDINKKIKYLNLEKIKVENDCFAMSEENKNLMKNLAHCKRELEVANSKIDGNLKLVNKLENNLSRCNSEKEKFKLEKEELVENLNVQRSMKNSLNAKISHLEENNQLLHSKFTIFKNGIPEIKKTFETAIDVKVKQHLEKQNEVKLKLPKALEEFKYSFNQINTVVRNNIENCCLLVETAIKNMQSLKKPTLISKDLEFFVKKPENFKAEDLAEEMVLVLNDIQTELGLIFINYKNFYDTAIENSIQVEKVFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY67</accession>
    <name>A0AAD5TY67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000483">
        <property type="protein sequence ID" value="KAJ3216344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY67"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="4">
        <location>
            <begin position="60"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3216344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="237" mass="27315" checksum="C92D154BD6E9AF73" modified="2024-05-29" version="1" fragment="single">FTEYVYQVVVAKEVLKNKEHLKNILIALDDPKPIIIPREFFDFSAPDPESAGGPLQSAIKQNTILSDALKKKPIELNVYDQFVNNMMKMGKKSLARRYLDLALKRLQHSADRYNEEVRSNRDIKEKIFLEGTPIDLLNEAVEKASPLIRLVGERRGSKVQLTPRPLHDRRRRRTGIIWILDACKESKSSKLKFDLRLANEIFAVLTGTSSVLQKKIQIHKTALANRSNINLFDRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY97</accession>
    <name>A0AAD5TY97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Adenylate kinase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AK2</name>
        <name evidence="7" type="ORF">HK099_007757</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000783">
        <property type="protein sequence ID" value="KAJ3212333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY97"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000106">
        <property type="entry name" value="Adenylate kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001329">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001381">
        <property type="entry name" value="PRK00279.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="6">
        <location>
            <begin position="298"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3212333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="385" mass="42937" checksum="7369E43441461F4B" modified="2024-05-29" version="1" fragment="single">DSGTGKSSLLLRFTDDKYLPQDQTKSTIGVDFKLKILTINGKNYKLTIWDTAGQERFRTLTSSYYKGAQGVILVYDVSNRTSFENLQFWFSELEAYSSPQNPVVKMIVGNKIDVENREVERIEGENLAKKLGTLFIETSAKSKFGVIDSFTEICEKIIEKGDQKSRSDRENVITINSGTTSPLSTQAPKIKDEYCVCHLATGDMLRAAVSAGTNIGRQAKKVMDSGGLVSDEIMVNLIKENIDNNAECKNGFILDGFPRTVVQAEKLDEMLENKNQKLDHAIELEIDDSLLVARITGRLIHPSSGRSYHKIFSPPKIDMTDDVTGEPLIQRSDDNASTLIKRLDSYHKQTVPVAEYYKKKGIWSGVDAAQSQEAVWASLAAIFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYE0</accession>
    <name>A0AAD5TYE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000540">
        <property type="protein sequence ID" value="KAJ3215472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYE0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="43"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3215472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="249" mass="29007" checksum="225AA955FD2A17B5" modified="2024-05-29" version="1">MSEDVLNNLQNTKNQSWNKYNDIITKPSSRVINMQQNSVHNQIICQPITSENVHSLRKINQSVFPVSYNEKFYYDVCETHPRELSSMAYMSGHVVGAICCRKEVLDSENFQYITPKSYPQHRPSQQQYQQLLQNGNSAKDSNLYNLNQNNFLIPPPVGRVYIMTIGVLDQFRRHKVGSILLQQIINQCVDDYTVDKICLHVHVRNEGAIIFYQRHGFRIETLVEGYYRRNKGVEPPNAYLLQLDLRINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYL1</accession>
    <name>A0AAD5TYL1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000786">
        <property type="protein sequence ID" value="KAJ3212281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYL1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3212281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="425" mass="47884" checksum="F3B83ADAFE1C761F" modified="2024-05-29" version="1" fragment="single">YLNFKSQSNFFFNWVNDPINNFVTADTVKDGGFSFIIDFGLGSYLSAGIAGTSLFSFIFTVLGYSMSKRGKIKNMFPYKQSKKKEIDSDDDDVKGGGDFRGNTITPSGSQVNLYDKYDNNQKLYDNENYDFQNQIPLQPLQNWNSNSNPLYSNATTPVQNYYEPKFVDYSSKDTSNNGGYTDTSAPSDVISSPVFNRNQNQQQYSPYTDNNYYTTYEENYSGTGASAPSDNIQYPDPVIATAPTWGGNGGRLGNANYNNHSQKKDNYNAPNSINYNGNASNSTRKVTKNINQSIKNGYAQNNVDNSNRFNDNYDYDTRPYKSQNEESRSVKASKSQYANDNVQGDWKSSTSSPKLRPELEITWQPKSKKDLNNLKVVNLDEDNDASRWSIYTEAPLPKNSASRKTYGTQSRTNRNYDNLGRGGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYQ8</accession>
    <name>A0AAD5TYQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005944</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000489">
        <property type="protein sequence ID" value="KAJ3216234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYQ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043226">
        <property type="term" value="C:organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCH" evidence="4">
        <location>
            <begin position="19"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3216234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="584" mass="67601" checksum="3994F157FD5A61D2" modified="2024-05-29" version="1">MNYLENYFDLSKFPKSTTEIVIKRLKKGMMMESEFAELIKERSLIEERYSNDLLKLNKKISQVDSEFVGPLENIFENVLKKNIEKSTIRKNFCKEILENLEKPLKSLNNFENFKFFEQESLKYLKDFELKNLKYLKHLKKKKSDNKLPALKLAMEQSKQTWQNESQKIFDSFFQMDENRIDFFKEILMKYITMDSNISQTEFTELQNLYIEIVSLESKFDILEFCKQNGNKGNADIKNEIGSSLSELESPSRRDSIRDSIKSFQRPSFGAKHHNVVSSQENIVASPQNDSERKIEEKDNFNNNLTQDARVQKEQENFSAYHIDSLKQNEVINEQTVQIVGIHNKHPQNVEEEQIGNQECNQRVQKDLNINPQSQFQHTDTHFGYNAQQQNGQQQNYHVEESINEVFQHEQNNQILKNMMVSSSPKVMENSGSVHTISDEGSEFKQTSPIKIDIKNYPIVEDEAAARNAMDLIASVLKPPTVNSVATARRRTTSQNRAQSVENPLLNSAFSIPVTQRSLSTNSPIFSHNPFLNSNQISQENVQENFEPYSSENKVTEVSISLNVNEQISILFNENNLIKVLLTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ76</accession>
    <name>A0AAD5TZ76_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U three protein 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">UTP7</name>
        <name evidence="12" type="ORF">HK099_005322</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000408">
        <property type="protein sequence ID" value="KAJ3217838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ76"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000378">
        <property type="entry name" value="U3 small nucleolar RNA-associated protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012952">
        <property type="entry name" value="BING4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040315">
        <property type="entry name" value="WDR46/Utp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085">
        <property type="entry name" value="WD-REPEAT PROTEIN BING4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08149">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01033">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="874"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="908"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="264"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="BING4 C-terminal" evidence="11">
        <location>
            <begin position="345"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00076453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3217838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1015" mass="115088" checksum="5C750400D937C94F" modified="2024-05-29" version="1" fragment="single">MKTASKISEHKKEDALLEPYLRGNHNIPIGNIKDKKLKGNLRKTEAKFKNAAVKAVQSELLLTEDKGFLEVDNMEKTFKFSQKILKEHVDMNTKNKMFELKLDEFGPYKIDYTKNGRNLLIGGKKGHVATFDWKSGKLGCELHLRESVKDVKWLHNETMFAVAQKKYTYIYDNTGMEIHCLRDHIEVNSLDYLNYHFLLVSVGNAGYLKYRDTSTGKIVAEMRTGLGRCDTMTQNNYNAIMHLGHNNGTVTLWSPNVTTPLVKMFTHRGPVNSIAIDRGGNYMATSGLDGHLKIWDIRTYKPLHDYYTPTPASSVCISDTGLLAVGFGPNINVWKDALKTKATSPYMTHLQPSCFVEDMQFCPFEDILGFGHSNGIRSLVIPGSGEANFDSMEANPYQTKKQRQESEVHNLMDKIQPEMISINPDFIGNLDRAPTEVKAEERVLEWEANNPTEKFVPKRKQRGKSSAQRKYNKKQSNVIDSNKLDLLKKIKAEKAKNALAARIRSGGGVIEERWDPFNRFKVNLEKSDRSTSLELNLSRTFGAIPVERPQDLTKSGKGTIFSSDLSRKTIQGNKTKFTAELKPRSTIQLLNGVKFEVSEVLSDNLIILKNPFEENSLPEKEVDGVSYKIIPHVDQGEMFKTVYDSLHKEQAIGIFPEGGSHDRSEFLPLKPGFALMALGAMDMYPGLDVKIVPCGLNYFNPDRFRSRVVVEFGEPISVSAELVNLFHNGGSDKRLAVQTLLDQTHNRLKAIAVTAPDFETLMILQAARRLYRPVHKKLDIDQSLEITRKFGLGYSKFQSEPKVLELTRKVKDYNKLLYAFGIKDHQVKNMAIGGYWAFKTLIKINDKSLEKAAEAKRESKVKIEGKDVIGSWKLIIGAVLFPAFYIFYTLIFGLYLKYLGHNYVFLKSLVFLFGFLPTIAVLTTLAYETELDIFQSLAPLVIASFSSSHQHESVRVMRSELQNLICEIIDEYGPKLENISKEDFNTRRIVKKKDVDYSKKINEDIKKNSLKAKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ77</accession>
    <name>A0AAD5TZ77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000426">
        <property type="protein sequence ID" value="KAJ3217469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ77"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="120"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="484" mass="55929" checksum="F8183F75E22E0CCE" modified="2024-05-29" version="1">MLQSSHTSIEKFIFSASYKLTLYITHIPNTENSTILKLHSMYSKMIDNMLMQYHSFNSAEFNELMKFTISSLRSINVSCGEILEEILIEASSLQLELNNIHESRKCDFINNEHKTFLVSSNLISFFPSEILLLILKNLSKIDLFELSLLNWHWSFVASEMLYKKIRVSFEDPYPLYKLIKCLKFNEGYHTYNNIYPSKRFLCTDLTLFSLLKIGLTNAHKTCVNILIALLPNLIAFSFTSSLDHYNKVGLDSIQLNCLLKNCKNLATVSLDYLDVSDERNHEKLLYLDNVKSLRELHLKQFAGYPLIIKTFLINSSFSSLTKLDLTNPGSDALLSISKTVKNLRAFSLCDYRGNVNEQEVIEVIKNSVNLISIRLEFLSSPRFNFDLVLLGLCDYNQNLTSITLIGARKVTSYGLETFFYNFSKNLKIFNFILFGFDMTEQIMRNILKKFKFKNLNSFELNLASQKYGLEQIKYFDNGSSQLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZI9</accession>
    <name>A0AAD5TZI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Guanine nucleotide-binding protein subunit alpha-13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GNA13_1</name>
        <name evidence="6" type="ORF">HK099_007007</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000646">
        <property type="protein sequence ID" value="KAJ3214141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZI9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="27"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3214141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="86" mass="10229" checksum="034A2C11CE10E7D1" modified="2024-05-29" version="1" fragment="single">MVDSIQLYKSVVLHPLLKNVPVVLFLNKMDLFEEKIKRIKLRIYFPDFNGPEHDLKKAKHFFKEKFEVATEKLINNVFYTTNTDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZR6</accession>
    <name>A0AAD5TZR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein mono-ADP-ribosyltransferase parp16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PARP16</name>
        <name evidence="6" type="ORF">HK099_005039</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000379">
        <property type="protein sequence ID" value="KAJ3218466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051838">
        <property type="entry name" value="ARTD_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21328">
        <property type="entry name" value="POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PARP catalytic" evidence="5">
        <location>
            <begin position="56"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3218466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="212" mass="24346" checksum="5926270365B27B64" modified="2024-05-29" version="1">MLYQNDRFMSELDFDNEEKLLFSWILKHQRYHLKFVDKDETFTNTASSSSDIPDIVFSIQKKTDIKFNPDNLKATVAFHGTNLGNLYSILNYGLNSHLNKRNLYGAGIYVASDLSTALSFATPSFGRKIKSKISMGATYKVVLQCSVVLHEDVIQNREQKERSFSFDEKVPATKKTKADKNRNDTGKKFISTLMFEWATICFSKLSKLPIWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZW3</accession>
    <name>A0AAD5TZW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BCAS3 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000358">
        <property type="protein sequence ID" value="KAJ3218948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045142">
        <property type="entry name" value="BCAS3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048382">
        <property type="entry name" value="BCAS3_WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268:SF0">
        <property type="entry name" value="BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268">
        <property type="entry name" value="BREAST CARCINOMA AMPLIFIED SEQUENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21034">
        <property type="entry name" value="BCAS3_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCAS3 WD40" evidence="1">
        <location>
            <begin position="187"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="697" mass="78811" checksum="E25187908AE7E776" modified="2024-05-29" version="1">MREVQSCTFGTLLNEAVVIICYKDEIIVYSCCSGDITQKLQISCIAIRIVNDTFYLTTNDSLSKYDKNFVLLKTLNGHRSSKILNNKKYIFTQQGNCIFSHSLNSLEVISRFTTDNNDPIFDCGESLLAYSSTVPNINVLNKQNASSHSTTILKNFTEYSYNKLLDLTNTSISSDSQTEHNSHLGNVVIQNIFSSKLISHFRAHSNAIAALKFNSNQTLLITASMKGTSFYVFEIIISFENSLEISSAVNCLYKLDRGYTQAHIKEFTFSFDSKFLLASSARHTRHLYIIEPVNRERSGPKMNSKQYALGIVNGLVDEYVKSKSFENDQVEFPLQCAIKPVSRIKPVMVKEYSSKIAPLSTFSQNTANEIYLLSGQNLSIHKIEFENMGNKVVIPSSPSSPSAGFSLGSSVSPKSSSCNNTSPLANFLSSSYQSFQNTKNNAFFEGGKNVNIFELSKFDLSASKIRKNVDNSNFLSTADRENEKSSWMAEIELSTFDSVSFGTPLWLNSQFKFLTFKPLQGDVEDNRKILRSEVLFFEDKKGYHPHDSKRERKREASMNRINNNSKINHSTIVGGIVRQGSEPGRPDYTELPEYEELSIRCEIAVPWSFSTIEQYSKKLAEAIDDELEVNETYQKKREGTLGVYLAIIKTKPLNLEVLSFEDAFHIELEEPVIDDEEKELSLNNSFNQMFPHKKKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U098</accession>
    <name>A0AAD5U098_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000312">
        <property type="protein sequence ID" value="KAJ3220214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U098"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="247" mass="27755" checksum="899A57B986772864" modified="2024-05-29" version="1" fragment="single">MTGYFLRSKSNLKVVENNDVSTTNKPDHIKLKTVKLKKPSKSHKNTIVDSYPHRNNQDEIVKLKRYSPYSSPPKIEKVLETTPVKQKKKVDLKQRLPKPKLKSKRAVDFFSTNLESNNSKLSVRTCDQVKLEELIENRASKDTTPPTSPVYSPTLKAGSSRENSISSVDDLVLFETESQAFFSKPNTAAVKSNFFQKLLLVKDAPSSPPPSKANMAVNLKSLNKKGSSIKKSTNSEKPKLARKNIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0D2</accession>
    <name>A0AAD5U0D2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_006370</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000543">
        <property type="protein sequence ID" value="KAJ3215438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0D2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3215438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="157" mass="17042" checksum="A406D86DECE4B194" modified="2024-05-29" version="1">MVNFSGAVSGFVAGTITTPLDVVKTYLQTQKMQTGTTFVDNSKLPNIQAIPASSKPFGLAGIVASQQRNLSAELLNSRQFNTSTMARNLSKQIPSSKIPSTPAVYPGVISAFRGIYRRSGVSGLFYGVGPRSFWCGMQSMIMFCIYESLINVLKEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0T3</accession>
    <name>A0AAD5U0T3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable quinone oxidoreductase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NADPH:quinone reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005688</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000455">
        <property type="protein sequence ID" value="KAJ3216880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0T3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003960">
        <property type="term" value="F:quinone reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05286">
        <property type="entry name" value="QOR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000053">
        <property type="entry name" value="Quinone oxidoreductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047618">
        <property type="entry name" value="QOR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF13">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="368"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00070796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3216880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="913" mass="102350" checksum="FC30E7C3F04D867F" modified="2024-05-29" version="1">MELKKLSDNFDSSKLTIEEVEMISTPTVTIEQQRKHSTIAITEVEDVTINTTIINENVDPGDKESEFDWGKNDTLSLKKRKRGCFSNLPVFLQNLLYAFFGSSFFMSFGLISYFFFVENKNVGFLSMKSNTTFFAIDGLPVLFYSVWLAISWSVFFGIRYVFTVLPSILVHISNSIFGKALDQDELASEVSHYIDYVRHLKKWLTYLIWSVVNLIVFVSIFSRFVMSSYQILFNIFASLNVFFGFFLAEKFLIQIFAEKQKFAEKVLDKLAKARKRNFNTTMNESSSSSSSFPVNTGNLINNISGVTKGVRKGVLGVAKAAFAKESNSSMTKDLQHGDPYKFAKKTFEALQRGNVSYLTLEDFIPYFKTKEEAAEAFLVFDKDGNGDIDKIEMKNCIIGIYQEHEAIELSVHQSSQAISKLDSLFKVFVYVAVLFIVLGIFNINTSSFLTVAISLWAGLLFALGGTVKNLVEAIIFLFLTHPYDVGDRIDIEGSQFVVKEFGLLTTIFTDTDGKEIYAPNPKLAGMLIHNIRRSGPIGEDIDTTKDQLEKLTDFLVNYLETEESREFFPVLKHNVNEFISSKSMIVSYFLNHKHNWQDNGRRGGIEVLEVKNVPKPIPTQSQLLVRNEVVGINFIDTYHRSGLYKVPLPYIPGREGSGIVEKVGEDVKNFQVGDKVAYLGENTNAEYALANPDYTIKLSELEKFENGAGILLQGLTAMSLTTLAYEVKAGDIVLVHASAGGTGSMIVQVCKNLGAVVIGTTSSIEKVKSSMENGCDYVINYNEEDVLAKVKEITGGKGVHCVFDGIGKSTFDLSRQCLRRLGTLLSFGNASGKVVDIDIMKLVPNAIKLMRPSLFQFITSKEDFQFLTIPLLEMMSKQKLHLNIHKVYPLENVKDAHFDLESGKTQGKLLLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0X3</accession>
    <name>A0AAD5U0X3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_004264</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000299">
        <property type="protein sequence ID" value="KAJ3220473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0X3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045891">
        <property type="entry name" value="ZIP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133:SF0">
        <property type="entry name" value="ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="320" mass="34879" checksum="D8D1901EBC3EFD69" modified="2024-05-29" version="1">MEGIVWLIVLCLAMGTGSFMAGSIPLALHFDEKKLKLLSTLGSGILVGTALIVIIPEGVETLYQLQNLIQNESQRDSLVDLKDPTIIRNLDIAEDNETVFKAHHYIGVSLALGFAIMFLIEHLGNSNHSHQHPSHITVSDMRNGSVSSNENKKGMSATIGLVVHSAADGIALGAASADGRGSLEFMVFLAIMLHKAPSAFGLTTFLLQEGYSRRTIREHLMIFSLSAPLCSLATYFFLLQNGVNEPHIMQKWTGILLLFSAGTFLYVSTVHILPEIYNHSSFAPLSPVTTASTQEKSITKLQIVVFVLGIFSPLFLMIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0Y7</accession>
    <name>A0AAD5U0Y7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007681</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000768">
        <property type="protein sequence ID" value="KAJ3212663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1544"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="282"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1713"/>
            <end position="1758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1788"/>
            <end position="1831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1850"/>
            <end position="1869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1876"/>
            <end position="1942"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="950"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1730"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1885"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1913"/>
            <end position="1923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1931"/>
            <end position="1942"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3212663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1996" mass="223738" checksum="E277640654298A7E" modified="2024-05-29" version="1" fragment="single">MSNNFHQNQFDQNNTSNENQESFGNTEYLNNQDSFSNQNHYNSGNNYLNNPQGDYLPNQEHYRGQQGEFSYNQNNYQHHHQQQKNFNTLDAQNQHYQNSVNAPYNNQQTFEHGDNYNQQHDYQNQDNFHKQQEYDTQDNFASVEDAMKNPQVTSNSSNFNEQQQNNQQFSQQYQQFPQQTSTDPDFKHGSQFPSFSGYSKGGESTQNNQQNQQQYSNYAFPATSGGLTNLAAPNAEFAVPTLNPPTTDFRRTSTYSNISSTSQPPPIGDERRASVIEIGGYGSADHPAIRRKSSPTAKKLSRLAPTPNGVSPPRLFGFQDGTIHNNGDSLGLSYSSPETFSTDLNPKYNETIYNTTHFSPTQLPSQPYTTHANEIPFSKGSQSVPQPFDYKNINEPVSDFPNSQILGNSINSQNQTQGNSPTIQQLSHPGIPLSPTIQQVHYAQASPISPVPISPLLIQQQQYFQENFNDNNDFSSQQPTQEQFSNHYNYATPQVKKNAVLNEGELVNNQDINERKQSMAFTEGEAQFIDPEGGSSNDDWRNSIAPEQTVPTSDINGHLNFAENSQMQFVNVNLANQGDISVQNSVYENNNKVVASVPPLDSADFLHSSVGTQNYPQSVTTNFDWIIPFSRDYYSNPTSEEKLVSIPFSSDIYRIQAVVFPKGVGLGKDTHLSLFFRPIKNSDEVSLGTQWRRQISSISVGLMNYDHSSGQRECVMQISYGRDHEIGIIGFDGESSTGFGQETFLAIEDVYSAIETDETLHFQISVVVEDEIKINTMEQHFPNPFIGVNLLEVNSCFTLPVFGSEDQKWQLLIYPDGGGVDEYGSKISSIYLKPIKNTLEVAMKENWLRILTGLTVKIYRGEQFFLIASKIFTGSFIFKYEFNETNPDFSLLCGWSAFVSLDELLFTEEQYYISVSIVTDDKANSDHYFYPLCNSIKNLATTSASLLTERETLNSKLQKALSEKIDAINEKSKFEKEVSRLEAINSILLQQLEEIKVKVLEWEEIVEETKKEVIVSKKEVEQKLNEIHAMKTRIAKAKMSMNSLRALMEENFTATAEAGVGTDVVTEEEDVESWEHLSDDLDLKSLSATEKVSELAMKGVASKKKLLTKTLLQQQSSVLKSEYLKLKAKLSALDFEVVELKNNLELKSTENQNLRWELDHLKSLPKPATVSKMDFTSTDDMYNDSESESGNPNIVEQMSSLVIGAKDAIEKAKSRASNFSDPGSRILDLASVAADLATVQAELEIARIPFIDIVAKTKAASSDPTQNLEFSEKEKQNIEVISSELEAVRKSLLDTLYNVGVQESNPGSAWSLANNYTGSRDLIGSQHLDNELSSEQKRKVILDSYEYKSLQKENLLITEKINALTEKFNKINELISVSNEHNNHKDETSENEIIFPTTTTHLNSTNFQNKPPVDSVAPNLQPAGDTFRTTAQVVNEETPLISQKIPLFIPPPAKIIAPPPMNSEFNHYRLSSDKALSPEKAAIGNTSRPGRLSITTTFDSSVPTLQHFGAGSDYQQFEKWEISKGKNVKVFETEDKTQKPSKSIFVFFCSVFILTLTIIFTLKYFCSVNNLRTLTLINDATKETILSYCLNFKIKESLSFLQGLSATTLETVMFGISRTVTITKLSGTGYFKLQKVLFLSNVNNTNNKVDLEVSFNENENNDKINIPYYGLTSDQSKSKLTTKLDAKIDSSQTSIVSSTFTVEKIVESPKIPFRKPKKATPVSKKENSNSSLTQNSATSPSSSAQSNENVETSTSEIKELPKLNSISIKKSNPVETVKLEHTPEVTRNEIKNEMNDEKVKMESDKDEDAIRTDEKSVNSKKDKGDVENLKTDDKKEKITSVVGLPEVVVEDSTQPVSEKENNINEDLDLTVDEAVKSNNDETETLDVTTTSTTITPEVAPPFSLESAKTPSTENFNNENTNLPENEEKSEVTSFSPTNLSSETFLTSKKESILEPSFTPITNEMKAKSIVKEPIVDDLRKLKKNLESEIPNVNKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U116</accession>
    <name>A0AAD5U116_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003918</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000265">
        <property type="protein sequence ID" value="KAJ3220889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U116"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041965480" description="Peptidase A1 domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="89"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="442"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="690"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="758"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="758"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="785"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="827"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3220889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="956" mass="106936" checksum="C1FC36CEF7670AA1" modified="2024-05-29" version="1">MNTMFTILLLLISSTSSLEHHIPLSTISLNKRLPDNNDNLLFLSRYHNHPAFKNGIQLEKTLFKRKKSLNNNDHNLGQKPLEVVDSDEFIAQIKVGKPPQKLDVKFTFSQQSWLLRAKRSVVPNEDFDYNELSEYSDDEYVNENSGSYKHKKSTSKLTKRDSYYNYEDQSNHHHYRVYYDDEYFPDISTLGFDPTRSKSFRHHAEPFTAVDGKNTISGKSGGRDIIKVASLKAKTFFGLSEVSPSKEYQGVLGFGLNKQGKDSDPKLNSWFQNMFYTTPECKVGIFGFYPSTSGHFNNGTAYKTDAEITLCGFYQNNGGSNLPSFEVTKSGLDNGFWQISLEKFLVGDVDVLVPKKKKYYEKDKYVEEYGYDAKVSKEKQKELDEEEENEEESEESEIENENQEGSSKLSSNYDYSYDYEEKSTKKSDGVDYYIKEIVYKPKIKFEAIIDLSIKKLIFPNKIFDRVIKELNGKAFFAKEHDGWFVNCDDIDKLPNFTFVYGGHAFDLLPNQYILSDFVNIKEEVYSDEEDGESDFSDYEVNEESGECSKNGIMRCNGKGFDTCDHFSWVHRDCGKGTACKQKGKNSVYCDYDRALSKRYTEADESESDDESEEESGYYGGYNKKQYYTKEVIKKICPLGFLSKKSRDTFIIGNVFLDKYASIYMVPPKAEDNYNYYHEYNYNYKEGKDYNDYKEGKGNYEEDEEDEEDFSDSDDENNQKKKYYGIKTFKRRGVYTPVLKKRFSLNAQAQISFQNLQSGALSARASGTTSSGPGSDGRRNPSDTINSNGNSNTNPNQNTNPNQNTNNNPNQNTNNNGNTNIGGGNTGNNGNNNVGNTGNNGNSNAGNNGNNGNNNAGNAGNNGNSNAGNTNSNSGNTGNTNAGNTNSNSGNTENTNAGNTNNSNGGNPNNGNSNSGIPSVPSNGNTGNTGNPISGSTNASTPVNTSAFPPPPPAFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U158</accession>
    <name>A0AAD5U158_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">mRNA cap guanine-N(7) methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">mRNA (guanine-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ABD1</name>
        <name evidence="12" type="ORF">HK099_005763</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000464">
        <property type="protein sequence ID" value="KAJ3216715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U158"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRNA cap 0 methyltransferase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3216715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="224" mass="26173" checksum="A70A2DB32B209E51" modified="2024-05-29" version="1">MEACGKGGDLKKWEKAEIRDLFAADIAAVSIDHARMRFSEYSYKFGARFVAMDCFETKISTVVPSNHLFDFVSIQFALHYSFESEQKARTALINASSNLRKGGYFCGTIPDADRIIKNVRGPKKRLEFGNSIYKIKFEQVDHTYEFGHKYTFDLMDAIDRLAKDYGLELVYKKGFHELFYEEIRNPEFRQRLHRMKVLNKKNTISNEEWEAIGLYTAFAFKKMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1P1</accession>
    <name>A0AAD5U1P1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000247">
        <property type="protein sequence ID" value="KAJ3221168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1P1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="408" mass="46664" checksum="F557B51A36900AA9" modified="2024-05-29" version="1">MESTFNLDSDLKSSILDFNIVDQSFFYNKLENLNDNNIGMTDEDIDVSFNNILSDLNITQDQSFLLNNENSFESDLAIKNNNSLSNTKCLQSPGDFFRQRSGVLGNIEGKGNQRERKNNTPNSRQIRTPLYQHSNNHKTPKSKCKKSANDNKTLKDNFLDHKLSNIQENLTQNDCKFSKSIFPKPDIEKLKKLKNNFNLEKPCELQKQTCVWNSTVGNNSTTLNINFSKGMDSKDITAVQFSTSFKDVKCSTTDFNTFEVPHSSCDKSMDDQKNLSATRELSSLSSLNLSSKSYTQDFYRNNILNFGNTNVKEKKVLEVMICNPNKSTLYLTGWKSEKPFYIPQFSKFSKKWPTSFHENGLIQVNPKSYLLLPVVFLPKYKGKYMSFLEIEIYNGDEILMGLVGYVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U235</accession>
    <name>A0AAD5U235_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Probable glutamate--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
            <ecNumber evidence="4">6.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glutaminyl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">HK099_003408</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Gln) + L-glutamine + ATP = L-glutaminyl-tRNA(Gln) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EC" id="6.1.1.18" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000223">
        <property type="protein sequence ID" value="KAJ3221563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U235"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1160.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000007">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.800.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2420:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1290:FF:000002">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1290">
        <property type="entry name" value="Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007638">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007639">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042558">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042559">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF4">
        <property type="entry name" value="GLUTAMINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04558">
        <property type="entry name" value="tRNA_synt_1c_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04557">
        <property type="entry name" value="tRNA_synt_1c_R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding" evidence="19">
        <location>
            <begin position="8"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding" evidence="18">
        <location>
            <begin position="166"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="16">
        <location>
            <begin position="256"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="17">
        <location>
            <begin position="568"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="20">
        <location>
            <begin position="677"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00070830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3221563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="783" mass="90384" checksum="6C3B7476CD5B0820" modified="2024-05-29" version="1">MTELEENEIISLFEAIGLSNQKALETKNNKKLCPNLINAIQSFGSIDNLDKTTGALIYNLASLITKDSVKHLPYISVCIRDKKLLSSDQILAAIKFCEDVDGEINDEEFNRYCGVGVEVSQEEIAEAVGEFFKLKKKELIEKRYTMLGPILGTLRTTIKWANPLLVKEEVEKRMLELLGPKDERDDLKAKKKEKKKENVNVKGAEIVTAPQISMAERAKTLKFVFEGELAKLHKAGENKQINPQLMKDHLKRTKGKVITRFPPEPNGFLHIGHAKAINVNFAYAEAFKGETNLRYDDTNPEAEEDQYFQSILKSIEWLGCKPTRVTYSSDHFQKLYELAIVLTKKDKAYVCHCTAQQMHEGRGGDTKGERKGCIHRDRPVEESLTEFRKMKEGFYAEGEATLRMKMDMNNPNPQFWDLVAYRVLYTHHVRTKDEWCIYPTYDYTHCLVDSFEDITHSMCTVEFVMSRESYYWLIDALEIYKPVQWEYGRLKLTNTVLSKRKLNKLVTEKYVAGWDDPRLHTLDALRRRGFTPEAINAFVRELGVTTTNSTIEMSKLEKVVRDHLNEVAPRLMVVLDPLRVTLTNLPYGHVEELELKEKDGSTHLVPFSKVVYIDRSDFSEEDDPNFFRLKKGMSVGLLQVPHPITCNEVIKDSKGKIIELKCNYDKDVKFVKPKTYIQWVGESSRHQSPIPVEIRLYSNLFHHSDPDNKEQVPGGWLSDINEESLQVKNGFMEVGIRHQLVPENKFQFLRIGYFCIDKDSDFEKNKYVFNRTVGLKEDSRKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U236</accession>
    <name>A0AAD5U236_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000605">
        <property type="protein sequence ID" value="KAJ3214614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U236"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16075" checksum="EFB655DFF89B0D8E" modified="2024-05-29" version="1">MQFIIFGKSLIVDGAIVYATLAAALREVEFNNATQVVPDTIVDIQQPLTAEFKPRVQSLLMLKYEKLETRNDSLLQEKTSNGLNSGIKYVKKSFLPTKDSPTDEIALLIGDPVSISKKYEDGWAFGINWKNNFSGIFPMSAIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2U0</accession>
    <name>A0AAD5U2U0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carnitine O-acetyltransferase mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CAT2_1</name>
        <name evidence="7" type="ORF">HK099_003814</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000256">
        <property type="protein sequence ID" value="KAJ3221036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2U0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF107">
        <property type="entry name" value="CHOLINE_CARNITINE ACYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00439">
        <property type="entry name" value="ACYLTRANSF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="6">
        <location>
            <begin position="34"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="659" mass="75633" checksum="05820DB44BBA8780" modified="2024-05-29" version="1">MLRSFNKFSTIKRNFYATNKNYITFDNQVNLPKLPIPQIADTAHRYLESTKPLLSPQKFEETSKLVQKFTEKGGLGEKLQNRLIDYAATRPNSWLEEIWLNKAYLEWREPSLINVNWWCNFLDSPVHDKLLLKKPPPSGVLSNFQIERAAGLITNLLNFKHLIETETLPPDVAKNVPFCMNQYRYLFHTCRIPQPKCDKLVVNPGATHIIVMLKNQMFKVQVYGKGCSRVSTAEITRQLLAVGKEGLISTEPPIGLLTAAHRDTWTKAYNYLSKSPSHAKNLKLIQDAIFVLCLDDHSTKNNPDHTHLQFFHNFNAENRWFDKSLQFIVASNGKAGVNGEHSPVDAVIPGRLFDYLIQNEPAVDPENVTESLLPPPELLKWRETTEELTDLINEAKTTVKKLINETESVLLHYRVYGGRYIKEIAETSPDSFMQLVLQVAWLRLHKEPTAVYETSSTRAFLHGRTETGRSLSNESLEFAKSFGNDDILYDEQRKLFRNAIQKHLETMKLCAAGKGIDRHLLGLRCMLQGDEAKDSLFSDEAFVKSIPGNRFYGGFGPVVPEGYGVNYAIDKDVIKLSISGKKNTKTKKNAPDVYQFRAMIERTLTDFMILFPKRSSIWGMDWKNLHEEERKEEVYFKSMAKASEDYLKRKTNLEKKYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U340</accession>
    <name>A0AAD5U340_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SWI/SNF and RSC complex subunit Ssr2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SSR2</name>
        <name evidence="3" type="ORF">HK099_001894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000159">
        <property type="protein sequence ID" value="KAJ3222789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U340"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12861:SF3">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12861">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05753">
        <property type="entry name" value="TRAP_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041940637" evidence="2">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="182" mass="20633" checksum="CE3529C64FDFC7C7" modified="2024-05-29" version="1">MRIFAYLLLTLLPLSVFSSLIISKEFVPEHLILGKDVTVLITIYNVGNKFAKEVTFNDQTTNNKTAWKLVNGTTKANFLAIPAYHNVTHSYVVKPLVLGEVREPFLVVKYKRKKQHLTARSGSKSSFVYTAGDYNAHFAKHSLEWSIYFGIAALCTVFPFVFYQTSPAKTIDSKIKDKIKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U358</accession>
    <name>A0AAD5U358_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">NADH dehydrogenase subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_001849</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000157">
        <property type="protein sequence ID" value="KAJ3222832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U358"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.740:FF:000012">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] iron-sulfur protein 1 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.740:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.228.10">
        <property type="entry name" value="Dimethylsulfoxide Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="11">
        <location>
            <begin position="23"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="13">
        <location>
            <begin position="101"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="12">
        <location>
            <begin position="240"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3222832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="722" mass="80195" checksum="1846F98A3F2F4CEB" modified="2024-05-29" version="1">MLRRLAFSAINKRLFSNTSIRKAEIEIFINDKPIKVEQGVALIQACEKAGIEIPRFCYHERLSVAGNCRMCLVEIVKSPKPAASCAMPAMPGMRILTDSPLVRKAREGVMEFMLSNHPLDCPICDQGGECDLQDQSIRFGSDRSRFSEFVGKRATEDKEFGPLVKTNMTRCIHCTRCVRFANEVGGAEELGTSGRGNDLQIGTYITKPIDSEMSGNVIDLCPVGALTSKPYSFTNRPWELKSTESIDALDAVGSNIKIDSRGLEVMRILPRLNDDINEEWISDKTRFAYDGLKTQRLEVPLIRKGEEFVPVTWPEALKHIKKSVQGIKGEEMTAFAGQLADAESLTALKDFFNLLGSENLRLDGRHMDQAIPSFTDFRSNYVMNSTINGIEEADVLLMIGTNPRQEAALVNSRIRKAFLRNNLQIGVLGNTTYAGDKTLNYFFEDLGKGVEDLKNLEKSSFVTEKLKKAKKPLILVGQSLLERSDSVAILQMISKLSLGLKSTLVTESWNGFNFLHRAASWTAALDIGFAPAKNLPTTPKFIYLLNADDIQTSDIPSSSFVVYQGHHGDAGAHYADVILPGSAYTEKDATYVNTEGRTQVTRAAVSPPGVARDDWKIIRALSEVFNVKLPYDDLQSIRKRMGELSPTLVQYDNVEKNTFTTLGLQQLSENNGVIDTNARLIDSSVKDYYLTDPISRSSSTMAKCSQVFFHKKESLKESIIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3M3</accession>
    <name>A0AAD5U3M3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Histone-lysine N-methyltransferase, H3 lysine-79 specific</fullName>
            <ecNumber evidence="2 11">2.1.1.360</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 11">Histone H3-K79 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DOT1</name>
        <name evidence="13" type="ORF">HK099_001558</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60328"/>
            <dbReference type="Rhea" id="RHEA-COMP:15549"/>
            <dbReference type="Rhea" id="RHEA-COMP:15552"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.360"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.360" evidence="2 11"/>
    <dbReference type="EMBL" id="JADGJW010000145">
        <property type="protein sequence ID" value="KAJ3223077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3M3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140956">
        <property type="term" value="F:histone H3K79 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000033">
        <property type="entry name" value="Histone-lysine N-methyltransferase, H3 lysine-79 specific"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030445">
        <property type="entry name" value="H3-K79_meTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451">
        <property type="entry name" value="HISTONE H3 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21451:SF0">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51569">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 11 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="12">
        <location>
            <begin position="265"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU271113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="603" mass="69217" checksum="57B1DFD7777482AF" modified="2024-05-29" version="1">MLKKHTRIKNESKLDFLSERVFYKRVLPVVEKNQSEKYKKFKSTLKNVDSDNNYSSSYGSVIYKESKIKAENPVSIQSEAYQHNSYSEDNFSIKQISPTDSAYEKSITINKKAVSKNVLNDNDNPKSNIEKFEIKKNLMKDLKIKKLMKLGEQSSSESITVPATSKSLVKKYTSVQKVLLDEKFDLEETLAKKKIKNIKKKKKIYFERSEEIDLKFIQSEDICLKYQDDYLLLGTQIKYNTNDKQLLKYELITVYLCYPGTNLTEKFPLILPKDPDDYNPCLDIRDSIQQIAKTSIPRSLQEKFGDSKVGIIRKCIKALNKKLPKDLKLAVEEFNSTLKQVKNTPEFKEFLNNGGVENLDEEFNKSTPNFDEDYFNSAEQFEFVSHVLEQSYARAISPNYNLLKQSGFSNNVYGEIKPKFVNQLINQCQIKKGQVFLDMGSGIGNVVLQISAQCMCDSYGVEILENTSKLALAQQKEFETRMKFYARPHGKIDLFKADFLNSKKVDDIMKVADVVFVNNYIFDPNLNNSILQKFLDLKSTCKIVSLRSFVPVGEKKRKISDSNSINSILNCQEFIFGRDSCSWMSEGGSFYIHTINRGSGGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U432</accession>
    <name>A0AAD5U432_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWR1-complex protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SWC4</name>
        <name evidence="11" type="ORF">HK099_002813</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SWC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000197">
        <property type="protein sequence ID" value="KAJ3221996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U432"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000087">
        <property type="entry name" value="DNA methyltransferase 1-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032563">
        <property type="entry name" value="DAMP1_SANT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008468">
        <property type="entry name" value="DMAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027109">
        <property type="entry name" value="Swc4/Dmap1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855:SF10">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05499">
        <property type="entry name" value="DMAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16282">
        <property type="entry name" value="SANT_DAMP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="115"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="184"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="706" mass="81643" checksum="8FFC015CA6837464" modified="2024-05-29" version="1">MSDVFDILNIQQHKPKIPQLKEKQKRPEGITREVFALTGGLPSLTIAPPTLKQKINKKARKWAIKQFTNSARSDNLSLYHWVRLNDDDTDSKFSGFNKTTFVECYTDQEYDQYFSDSNWSKEDTDHLFDLCKKFDLRFIVIADRFSGSQERSIEDLKDRYYSIVKKLVSLHDKAADTSIYNYNKEKEVERKKNLEVLLNRTTDQAKEEEALYFELRKREQTEKKWMKERESIVCLLGNYESQKDSLFLEKKKKRLNKKKKLEDGIEEVDTPQKKEKCAPGVYLRSSRVAPVKTTMQQKLNTSLQELGIQNGKPTMPTAAVMAAFEELRQQILALLELKRQIDRSDHDLKLQQSRNLGSSIVKGTEEDDIESGSSRRNSVGIEKMREITDIFENTDEVRASSMVKVSSGPSNFYDNFYSTTYSTLHEYRKNLGRSGPAEIFQTQPIKGGINREIVNPQDKILREKFFLRNPSVKSSSGYSKNVIPFVAYKKEVDENETFNIKEPFLTNYEHDYKTPEEAPVASVGVLGYSGFCRIPLSHKQKAVPNNAFYTSTTHKAHQQGQYTQKMPLIDYSKIIPSDSGFTSDVEHILSLGTKGGDERFKMFRLKLGKKEPTGAVRNNDVYLFKKENLSVNKRFLTNNEIDFGLSLKKLTGVNSDINYTKKYINEVKRSGYSLNQKYEYERKLEDEYTGVHSTIKKYKELREPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U460</accession>
    <name>A0AAD5U460_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000113">
        <property type="protein sequence ID" value="KAJ3223897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U460"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="535" mass="57095" checksum="1FAFEA1C05D371F3" modified="2024-05-29" version="1">MSKIPPQIPSKISTPKEIHSSQTSCNVENVTGGRKILYMKGLLDHQGGLKFGPPPVLPKKESSGDIKITSEELSSPENSEIPSNVSTVKSKISSSTVAKEKFSSNSQENDGLPFNQDGRKIKYLKGFLENANGGFKVNANVPDETLKVESVDTLSTDFQLISPVLKPPTLLPKPQKKISDTELQAVPLPSTPSVITKPQVPKPQVPKPIYKESSIMRTSSTTTTTTTPVVKETFKESNLAASSPQRKTTDENSSPNGILQPSSSPLSKPSAETKENITSTISNPHAPLAKEASKHNITTSIPAIVTDTAKPLRKEDSKTIVITNDAAIIAINPLSSTPITVKDAANISPKINITAANLSPTTNTQPPKPVVKESANCDVKANIKTVNANQNQPPKVIVKDNLNDETTKQDVAVSSQQTVKNLEIKTSGNIIAASSACQTVASSPQVAKIESKLPGGVNPKLPPTNNEKQEIRIAEPTIHKDAGLPQSQVGLNSNAVDGIPKSSDPLKFLANYCYSCGHGFGAKDKFCLDCGIKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4C8</accession>
    <name>A0AAD5U4C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_000650</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000116">
        <property type="protein sequence ID" value="KAJ3223820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4C8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="255" mass="27716" checksum="0D8D6026D96DEAF8" modified="2024-05-29" version="1">MAPIPISSNAKAGVSSFLVILVSEIGDKTFLIAAILAMTNKRLLIFTAAFAALFVMTILSAFLGIVGQNLLNKKYTQILAGILFFVFGVKMLLDARKMTGKELEEETEEVSKELLEKEEEEKEKKSSLEEGNISKKESTGFAAGIHNLLQFLFSPVFIQTFVMTFLAEWGDRSQIATIALAGAEDFLYVTLGGLCGHAICTCVAVVGGRLLASKISIKTVTIMGGILFLIFGFTTFYSVYAGEENSENYDIPSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4K7</accession>
    <name>A0AAD5U4K7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 17">Dihydroorotate dehydrogenase (quinone), mitochondrial</fullName>
            <shortName evidence="17">DHOdehase</shortName>
            <ecNumber evidence="4 17">1.3.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">URA9</name>
        <name evidence="19" type="ORF">HK099_004842</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>(S)-dihydroorotate + a quinone = orotate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="17">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 17">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Mitochondrion inner membrane</location>
            <topology evidence="1 17">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="4 17"/>
    <dbReference type="EMBL" id="JADGJW010000355">
        <property type="protein sequence ID" value="KAJ3219049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4K7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106430">
        <property type="term" value="F:dihydroorotate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009220">
        <property type="term" value="P:pyrimidine ribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000066">
        <property type="entry name" value="Dihydroorotate dehydrogenase (quinone), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003645">
        <property type="entry name" value="PRK05286.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003652">
        <property type="entry name" value="PRK05286.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF4">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 17" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 17" id="KW-0288">FMN</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 17" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="18">
        <location>
            <begin position="73"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3219049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="573" mass="64483" checksum="9B973A3FFFC5D150" modified="2024-05-29" version="1" fragment="single">MFISDCYIVHRAYLNFQAWEMRHNDYARSEIHKQLFMPLTHLLFDAEESHKLAIWLAKHNLSPKDLTEDDVILNLKVWNKKLSNPIGLAAGFDKNGEAIDGLFDFGFGFVEIGSVTPLPQPGNPKPRMFRLKEDKAVINRYGFNSFGHNEVEDNLMSRVRSFLRKNTIYHTNDEVLNNVNKSLKSGKLLGINLGKNKTSPSESDKDYLDGIRNLGSYADYIVINISSPNTPGLRSLQRKEPMLRLLNDAIKTRNKLENRPPLLVKIAPDLNNEELEDIANVIQESKVDGVIISNTTITRNNLKSEYRTETGGLSGKPLLNLSLETVKKFYKLTNGQVLIVGCGGISNGKDALKFCKAGATLVQVYTALGYDGPGLVNNIKSEVLKELGEKKWQELFESGYTVDVKCNDCEIDDEDNGVNVDNMNIDAPQAKKDNPSTNIFISSNNETQTNLKKKLLKELLNSNKTKKRVREEKPTVDCEVCKFKLGTGGVRKGIINENLNTSPTISTTGFFNLDQNFWEEPSFNVEVVCLKCVDKYLFCSECGGGGNKRTGKWRPKQMFQSKRKTCSLPHIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U597</accession>
    <name>A0AAD5U597_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cyclin-dependent kinase</fullName>
            <ecNumber evidence="3">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CTK1</name>
        <name evidence="16" type="ORF">HK099_007731</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000078">
        <property type="protein sequence ID" value="KAJ3224866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U597"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008024">
        <property type="term" value="C:cyclin/CDK positive transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000124">
        <property type="entry name" value="Cyclin-dependent kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="210"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="15">
        <location>
            <begin position="681"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="12">
        <location>
            <begin position="681"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="519"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="626"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="719"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="765"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1064"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="539"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="570"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="635"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="719"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="799"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="823"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="845"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="860"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="904"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="932"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="950"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1064"/>
            <end position="1081"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3224866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1272" mass="146025" checksum="1D8D12B8F6A70FB8" modified="2024-05-29" version="1">MSNPNHNYPSSRYSSQYPHNYYAQENYYSHGDAAPTPSAPGYPNYYTASSHNYYGHGQPPSTYPNYYNRPENYYNQTPTSLNAGHQPYKPTPYPAPPNSILPAPPLFNTRRKSIDSMDIESNSSIKSIENVVTQLESPQLTQKKSFNLNKKLPSVSNPFIYNSSTIKHTVDTINSKPEEKILIEKNENEKNLISDCSFDKVRIAFNMDHYERGVQCGEGTYGKVYKAKHKLTGRIVALKKVLVDTSSSKEGFPITSIREIRILNATRHKNIIQLMEIISIKDKDSPSIQMVFEYMDHDLTGILANNDLKLEPQHIKCLLKQMFEGLDFLHSKGIIHRDMKGSNLLLNSKGELKLADFGLARNLFNGSGCGIQKKIDFTNRVITLWYRSPELLLGATNYKFEIDIWSTGCIFLELFDGDAPFRGTNEIEQLDKIFRICGVPTKTNWPEHTQLPWWQMMKPKHLHNRIIRSSYSKKLSPYALDLLDHLLQLDPKQRLTCKQILEHELPKIEGDWHEYESKQRRRIERTSSQQEQHAGDSISHSRRESFEPSANSRRESFEPSANSRRESFEPSANSRKTSFEHNSNSRRGSYDETLTSDNNATFQIPSLGRVASQSYVKSTFLQQNPQFQKPLHLQKPPPPPPPRNPPPPPPPLTGAKRRFEMVGREDIQNQKMMDQELVKKYSAATYCKYITAASCQFGEKCKYKHYRELKAEEKVSMKPGDEAFSTKKAQKDKSVTLLENSKINEVSRSKDFDEKLTKLLSSSEKGADLHEKIALTPTKKPIGRNSLPFSKYSRRESPSTDSLSSSCTSDSSPASRGRKRSYRSSSSSGRSSSRSTSRQRRSGYYRRSTTTLFRRSRSRSPPDSRYRRDYDHGRDRVRDRYGSSRDIYPRPRSRDRYSQISYLDTRDRYPESRRENKDWKTIPRRERSPVTSSRGRSPPRYRSEYSNSRSDYDRDRRSRKKSDSPPSKRERSSVKNENGDYDQKIKIEEKVSARNDGKDSTYDSKIDDVANKSFKEREIFPDVKLAALSNSNKSESSEFAIKYEIPESNKHALDFDMEKQITSKSVRHGESEASKNDKPGSKDSSTLSAGQKTFEMDLVDSKVIVDSNSLKKSVSKELKEKTSEDNHLAVIDEDEEIIEEIGGNVVPLYAAEKYHSEREDIPSNNNITVSAASHFEYSNEMKKHAFILVSSDDEEEIIEEEVGGEIIPLLKENDSNCLLSNKQQMSHAKSDLEFDNITIRKENIINTHNEFVKIKVCQGNLFQNNKRHLLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Z5</accession>
    <name>A0AAD5U5Z5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit delta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">EIF2B4</name>
        <name evidence="11" type="ORF">HK099_002347</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000177">
        <property type="protein sequence ID" value="KAJ3222403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Z5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233:SF14">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="46"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3222403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="481" mass="53716" checksum="8005DE56303E4546" modified="2024-05-29" version="1" fragment="single">MSEQINGPHQSNKSKKKIQTQNMTKAERRELQEKQRAEKNQKKQENTQLNLAQQKKTQQLASSVSSLDLNRTSQPNQLSASTPNIRKPPAQMRQDDPKMVKKIEKTQTVQRIPVQKPVALFSHLTQYEKPQSNLAQDIVHPSIISLGLKFSEFVIVGGNARCIAMIDVFKKVIHDYVTPPGSSLIRHLTMYLGKQIDYLTSARVLAASMKSAIRHLKSEISILSIDLPDIDAKEKLYDELDNFILKNITIADQYIVHQTLQNIHDGDVILTHARSSVVLAVFQAAYDMGIKFRVIVCDSRPKLEGKELLKRLVATGIPCTYILSNALGVVMKEVTKVIVGASALFSNGAVMSRAGTAVVAMMANEFQVPFIVCCETYKFSDVVRLDSFVWNEIGDSDELLDLTNSEPSSKLPSVVPTLTNMQSNASMIRRSEWRNLDSLGILNLHYDVTPSHLVTMCVCEIGIISSTSVVTVLRDLLEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U678</accession>
    <name>A0AAD5U678_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phorbol-ester/DAG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_005876</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U678"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031106">
        <property type="term" value="P:septin ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053026">
        <property type="entry name" value="CDC42_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006614">
        <property type="entry name" value="Peroxin/Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00694">
        <property type="entry name" value="DysFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00693">
        <property type="entry name" value="DysFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="926"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="7">
        <location>
            <begin position="2"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="DH" evidence="6">
        <location>
            <begin position="156"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="8">
        <location>
            <begin position="667"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="446"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="540"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="820"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="314"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="469"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="485"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="501"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="556"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1201" mass="137223" checksum="3B1C340CF5D7F7D3" modified="2024-05-29" version="1">MSHTFKVYNYSGPTNCDSCKKFLWGFVKQGYQCEGCKFNSHKKCLSEVCHLPCSALIQVGAPFQHNGSDVDSSVVMNEPVASLGQNSNDIENNSSKAISLHSNGTGSVINLTSINSLSTLNTPQLPTHSRTESHSSFSSITPTVEVSSNLITTCDNRAMVIRELLETERKYVADLDTLYKYSKDVQQNNLLEESELCMLFSNLPDLLRFQSKFLSLMEETFLLPSNEQRIGLLFSQHELNFVVYEKFCANYKKATQFLLQEGHKLNSLKDVIEPFYGLPSYLIKPIQRICKYPLLIKEIIKYSEDKSYPFMDEILIAEDVMKRVTQKINELKRLEENEEIKNSLKEQLINSSLRGSIYVSSIGGVQDTSIISQQVFGLKVFWKDGDVMETFALNCKNMEQATLWKSRLETLMEAEKSRRRASVYALQQSVRNRVFRVEDDTEDFDYRSRDSGYSSTSGGIRPRGRSDAGDTSSDALYATANYNASQRSRSRTSYTRSKSQPRTQTIQPLWDTNNLPPVPVQYRRKNSENFISPYTPTILNNTIAPQSAPIQNMRRPSRDQRSGERRGSRDDRLEKNLPKKSRDERLGEPRNDAEARMLARRSQILFPTQETYTLEDDSRLRLNATTDAVNKTDAEARLSAKLKQLRQSSNATKEREKTAPTSPEGFTMKILATYAGDVFQVAVSPEGLTYKELVLKIEKKIKIFHKLAEDKRLRIKYLDNNKNEYLLINSDSDVMYAFNSSFSRGTFGEAMNLYYCHCNAHKKCKGQMQDPCPAFLQDMLDEDAYLDRDYTYIGEDSSVVIKDEKEESILSAANNNNTLTPSMSASLAPPHNNSRTFTRSKTSPSFSGSDTGSFINELAVNTAISSQEIKKASSIKTGLTARLNFATTMPKNMTRFIMRLGPLVAIQDDLIEIFTWKNPYRTVAIMLVYIILCLYPTLFLIVPQTAFIYYLIKQYYRKTKHIAMNKKETKINVNLQYLKNLQFIQNHMGAFADGYDEISRFNRNILTWNDEDETMKVLKIAIASIFGVVIFLRLVPTSWIFLGGGVFLFLQHTALFRAASATLPPVLMRNLQYRVDFVREAILNVTKAGTTGKTTVQLYENQRWWAGLGWIAHLLRSERVAWSDESGENAKPSKDDYELPGVEWEWASDDWKIDMAWNSTMDENGWVYSDHNWLNIQNKPGVTSLTRRRMWVRTMQLKKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6A7</accession>
    <name>A0AAD5U6A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000045">
        <property type="protein sequence ID" value="KAJ3226068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="550" mass="61323" checksum="904C9AE6325CBE79" modified="2024-05-29" version="1">MVYGEISPNLIANGDAEAGDYAWNWNNASGSQLQVASYSSINITRGILLNQKHILALGQSCFQASSSISDAPVKRIFSATQTILLPEYARNSTLLGLTNFKFSASFIRYFSTKDYVTINLSFTDINNKKLNFNSQDALSLVYKNDVGDILGGNIKPFWGNSSAHAYFFSEVSNGTVPINSINIVIDMIFYLADDEESLVSKAFVDNLALTLFYLRNKPPSFEILEPETIQAITPTGYIGIFVGGLGLFLLFIVVPLFTCFKKQASPILKRFTLKRRNSKVTLFKKSINRFSALYTFSRNKQGSNRPYSFPQSSPVPVRQSNQFLPKLVENHIAEEQATTPVKRFPNLNQSFNPFAMSIRQQHQSQQAVNHIPIRQSNLRNGFISDEDFQYSADATPYEEHSIVLGSESLQSPQLQFHKYESLHTPTAVFPPSELSQLYGRNFEPSNVNEVATNEFGAADCTNTAGKLKLALKNIKSKWYQVSGVYESNFNIQLAIIELKIMQSCGDGEDVAGDYLCQLDLHQQKFNLQCQSLSTSGFKTVGPCPGQDDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7G3</accession>
    <name>A0AAD5U7G3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7G3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="170" mass="19556" checksum="640D66D0A5BA33D6" modified="2024-05-29" version="1">MFKNAEDLKNNSSEKKKIYFRNFKNSLKSIQEKRGELVNINKKNKKILQLEKVRVNLIKFLVIWLSFVIGTLIAYTINRLPGKHLYSLNAYSNTNINEVAISAIHIARTLELLIYFKYMDILKSIVLVGSGRIRIDDSKPVTQLSSVNFSRISKSVVSPPSPKDFEDSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7I7</accession>
    <name>A0AAD5U7I7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001921</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7I7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="4">
        <location>
            <begin position="178"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3227465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="466" mass="52624" checksum="4DA31B07ED201602" modified="2024-05-29" version="1">MNNEEVDLELAVSLHSTLRNEPITKKDSKFQQHLKTLRFIMPYLPTALYSVPQYYLRGPAVKSWPLQLHVLINVIKRFSKIANNETSTPYQLQSFTKLKQALPIGFILKPIKVKRSIKAVNFFKNGGMLFSKFPKEAELKNFEFDEELTREKNNGFAGPGVDCDWIFKNGLEDSKKVIIYLHGGAYVFGSKEVYRRLCSQYSEGAECRVLAVNYRLAPQNPFPCAVIDALSVYFYLLDEGFSANQIVFSGDSAGGGLALSTLLVLRDGGFSSPAGAICFSPWVDLTNSLPSFRLSGKTDYLPSQARDLKLGDRLHYYAENKELRNPYVSPLFAKSLRGLPPILIQVGSVERLRDECVLFATRASTSFLKNNSDYDIFDHTKVQFEIYEDQVHVFQIFHFLPCSVTAMNRAFDFCKSITDESSVEKLINFNSSNNLFDPAGKLVKMVTFDPTTGLYQKNGVLRSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7K5</accession>
    <name>A0AAD5U7K5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7K5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="364" mass="41649" checksum="AC0BBEFF7F1F6029" modified="2024-05-29" version="1">MTKISFVSNSVTLDVNHDDGKCTVSNKYHHGINLNNSELTTINIDFDLTNVDGNEKLKKAGIKLSIKNGKYLENKLSCESLNPKNKLAVGDFIKFCLKLDCLRNKTSKLCTKLSDFDAHLEFTHVDGFVDFSELVPSINKIKSKLRNIADFSESRANNNVKNWRFKEVSLDTVVGANLLLNLDDKFEKNDHFLVHHSKKNNILELMLKHHINIGKESVDRDARKILLENYPCNILMVHSLMKVPTKIKKSVNMNADANCELTKNVFGDLEPKTRILNSKRKIVSEVLNSYTDNDSIINIRKLKKKKMVAKFVVNEKLERGVNTGNFFKNDEYIRSKRKSNRVRIPNPRFTRGLTASCNIEEMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7U9</accession>
    <name>A0AAD5U7U9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Suppressor of glycerol defect</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SGD1</name>
        <name evidence="6" type="ORF">HK099_007826</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7U9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF4">
        <property type="entry name" value="NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="5">
        <location>
            <begin position="650"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="181"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="245"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="899" mass="103258" checksum="1A27C1D00695C53B" modified="2024-05-29" version="1">MSISLPSSLTSQLSELDSNDSRFNYKGFSKKSLKRKALRKEERKLKKQKMNLFQTGKSKLTVLPSENIKKTAKLEKSNIHLESDSEKRDRIAEPNKKKKKREISNNEKLETLKKQNPHFHELLTGESKFYNSANTSKEKFEQDDKLIKMYAKKLKLKKVGKIPSNFADDGLDFLFEDLTLPGNLNSSSEYQEGDKERSDLDETEFGDQSIAEDSDDFEGSQVGEEEKMSLSDSLNFLENLDEEEGNSVDNDAVFSSGEYSNSAEEDENFSDNYNADTSVEDEKRSTDVNIALSENTNSHFLGKNEQNRAKLIDSQNKYVPPHLRLKSASLSNTTDTNIKLKKQLIGLSNKLSDMNIGNIVDEVEVILRNNTRNEVTTEIINNILNQISDPSLNLLDSFHCLHAAFVSSLTILIGNEFAATFIQKLIETFETERNFYLNTQNVLNKNEVGGDSNAANDLSLKIEHSKKKSSNLVTLFTFCYNFNLINSSLLIDLIKLFLESGLNELDIENLLRMLKICGSKLRNDDPTAVKEIVVLLQKTVKEVQELSPRAKYMVETITNLKNNKKQKQKADGLANILQTEKLLKFLQKRGLKEPLRVTLKDIRDVPEKGKWWVVGAAWVGREENFVKEMENSKNVGDLEMLARAHGMNTDVRRSIFIVLMSSEDCVDAFNRLSRVNLNATQQREIVKVLLHCCAQEKVYNPYYTLVLQKFLLKSHSFKITFRFTLWDQLKLLKEKEDINVSLINNLSRLTFYLIFNESVDFTVLKVLDFTDLNDQQILFLRILFGLLLFNKNELKFRATFKKIVKSNELQQKNIQKNSKKRKKVEGSLDNVEDMDNNNFLDGLGFFFNKYVKNEIFRKKIKRVDGEEVVNVGGFFSIFFANFTLESIKLRIEYLKTIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7W4</accession>
    <name>A0AAD5U7W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7W4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04139">
        <property type="entry name" value="RalA_RalB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002309">
        <property type="entry name" value="Ras-related protein Ral-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="167" mass="18669" checksum="A0DFBAAFBA9A3D37" modified="2024-05-29" version="1">MVKKVAAKTDLPLHKIIMVGSGGVGKSAITLQYMYGDFIEEYDPTKADSYRKKATLDGQECMIDILDTAGQEEYAAIRDNYYRSGEGFLCVFSLTETESFSNTSEFRDQICRVLDDEKIPFVLVGNKCDLTTQRKVTTAQGEAKAREWGCSYLETSAKTRLINSSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Z8</accession>
    <name>A0AAD5U7Z8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">proteasome endopeptidase complex</fullName>
            <ecNumber evidence="3">3.4.25.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PUP1</name>
        <name evidence="12" type="ORF">HK099_004697</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000034">
        <property type="protein sequence ID" value="KAJ3226521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Z8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03763">
        <property type="entry name" value="proteasome_beta_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000005">
        <property type="entry name" value="Proteasome subunit beta type-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024689">
        <property type="entry name" value="Proteasome_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF4">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12465">
        <property type="entry name" value="Pr_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0888">Threonine protease</keyword>
    <feature type="domain" description="Proteasome beta subunit C-terminal" evidence="11">
        <location>
            <begin position="229"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3226521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="270" mass="29607" checksum="385B4B5BD4525EF4" modified="2024-05-29" version="1">MALKFELPKSGFNFDNYNRNLILESKGLKSPKTIKTGTTIVGCVYKDGIVLGADTRATNGPIVADKNCEKIHYLAPNMYCCGAGTAADTEFTTNLISSKLELHRLATNRQSRVVTAMTMLKQMLFRYQGNIGAALVLGGYDVTGPHLYTIAPHGSTDKLPYVTMGSGSLAAMTIFENGWKKDMSREEAIEIVKDAIESGIFNDLGSGSNVDVVVITKDKTEVLRNYKRPNERVKKEQSYKYPRGTTAVLKTSIRNFVDVTEGVATPMDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U853</accession>
    <name>A0AAD5U853_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U853"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="329" mass="36227" checksum="DB6A464807DFF107" modified="2024-05-29" version="1">MIFLKATYVESNLTEVRRVPLVNQELTIDELHIMLKRLFKTKNFDNTIFKYKDHDDDLIVLENDDDKLNSIKSTIKDLDLKIDLILKEVNDAEGGNTVTKAGSLKSPVKSLSVSDMAEFELKTTGSTNQQLQQAPAVNAPQVHANHRGGQQNIVQPPPPPLQQSHLSQPQYNPSFTGQQQPNPSYSGPHSQASQQAPNYPTHSSQGYAGPPPTSNLSTASQASQSINYSGNAQTPQSYAAKQSAPPSGYSQPQNYQGPAAYATSQSSQQSSNYPTSNPPYQNAPTAQQNYQQNPTHPQSQQFNSNVPPNQYNQAQQQPYSTGYPGYQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8B5</accession>
    <name>A0AAD5U8B5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Midasin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MDN1</name>
        <name evidence="13" type="ORF">HK099_007688</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the midasin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000077">
        <property type="protein sequence ID" value="KAJ3224894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000142">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000582">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001053">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001368">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001384">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040848">
        <property type="entry name" value="AAA_lid_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048617">
        <property type="entry name" value="MDN1_AAA_lid_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012099">
        <property type="entry name" value="Midasin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041190">
        <property type="entry name" value="Midasin_AAA_lid_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103:SF2">
        <property type="entry name" value="MIDASIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103">
        <property type="entry name" value="MIDASIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17865">
        <property type="entry name" value="AAA_lid_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17867">
        <property type="entry name" value="AAA_lid_7"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21108">
        <property type="entry name" value="MDN1_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010340">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="12">
        <location>
            <begin position="5032"/>
            <end position="5226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="4347"/>
            <end position="4401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="4414"/>
            <end position="4759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="4813"/>
            <end position="4835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="4853"/>
            <end position="4882"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="4907"/>
            <end position="4934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="4348"/>
            <end position="4358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="4414"/>
            <end position="4425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="4432"/>
            <end position="4448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="4487"/>
            <end position="4496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="4515"/>
            <end position="4528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="4529"/>
            <end position="4540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="4549"/>
            <end position="4558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="4559"/>
            <end position="4577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="4609"/>
            <end position="4621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="4630"/>
            <end position="4647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="4665"/>
            <end position="4675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="4676"/>
            <end position="4685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="4709"/>
            <end position="4728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="4729"/>
            <end position="4759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="4817"/>
            <end position="4831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="4859"/>
            <end position="4870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR010340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3224894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="5236" mass="598539" checksum="8B16937BFDBAE698" modified="2024-05-29" version="1">[encoded data, 5236 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8D1</accession>
    <name>A0AAD5U8D1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8D1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010393">
        <property type="entry name" value="DUF991_YecM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37519">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37519:SF1">
        <property type="entry name" value="DIHYDROXYBIPHENYL DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06185">
        <property type="entry name" value="YecM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="154" mass="17958" checksum="FC40F4DDB1AB03DC" modified="2024-05-29" version="1">MIIDHICYRVATTEEYNIRKEELLKLGTLLIENPIGGRLISTFKLLNPIAFHDRNIYLIELPSPKKGSFYNSGLEHVEIVTTKKLEEFQLDYPDVTFNKKSFYKPVNRDLRFNSLFSNTNLSFRLDFEGNISVKFHEDTLENVINREIAEGLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8D3</accession>
    <name>A0AAD5U8D3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Platinum sensitivity protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PSY2_2</name>
        <name evidence="6" type="ORF">HK099_005220</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8D3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072542">
        <property type="term" value="F:protein phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055236">
        <property type="entry name" value="EVH1_PP4R3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006887">
        <property type="entry name" value="P4R3-like_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051137">
        <property type="entry name" value="PP4R3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318">
        <property type="entry name" value="ATP SYNTHASE GAMMA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22972">
        <property type="entry name" value="EVH1_PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04802">
        <property type="entry name" value="PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PP4R3 EVH1-like" evidence="5">
        <location>
            <begin position="4"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central" evidence="4">
        <location>
            <begin position="125"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="634"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="798"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="639"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="661"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="812"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3228210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="823" mass="94409" checksum="0276685CA06A56A1" modified="2024-05-29" version="1">MTYRVKLYKLDQNGAWDDKGTGYVCITEHENLNTIQVSKEQDSSNLLLNVKLIDDDVYQRQQETLIVWTEPDGENLALSFQEAEGCNEIWDQIATIQRKLMLLSGDEYNSQLNFPPPEPSNLKDIEQSFLSASRSVIGRDNAIASIIEQKYIDKLVELFEKVEKSYMDLENEKSLDNLFTMSNIIKSILFLNDASIFTLILQENVFLNIVGMLEYDRDFSTAKANHRQHLLHHAQFKEIVPMEKHIVDKIKLTYRVQFLKDVVLARLLDDGTFSLLNSFAHMNHYEIVSYIQENEEFLKNLFSIWTDQNKSEESKNDVVLFLREYCSIAKGLQFAHRTAFYRSLCHHGLFTIFSSSLNNSQLAIRIAATAVLSNVLEHDPSLVRSYTLAQIRQSQPNLIFQVIERLHDEPDAGVRSQYSEILRILIDGPKNDGVIEKIVTPHDSEIDEFLNFFYKTETADMLMKPLINLPEKSKFSFSSGIERLDISRDEASICNHLCEILCFSVKNHSYRSKYYILASPLMNGVLLLLKCKESYIRLSALRFFRTCVGMKDEFYNRHLLKLDIFGPIIQAFNETKSKYNLFNSACLEFFEFIRKENIKTLINYIGEKYSKSFDDVDYIDTFSSIILKYEQSKDPCSGLDEKENSESQKLEKDGWSKVDKSEEDYFNTSDEEENESTTPQTSSVIKDSSLSVATSPHLSNSLTLGVGGLVENYPDDEEEEEFPLRKKVLVVKSNSPTTNIFSNLNKNKFKSSININNNTSISKTVKSSSVIDIGNNVKVKNIYGSDDNNLQADSETFLNDDNDNSNLTSSNKTANCNLKRQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8E3</accession>
    <name>A0AAD5U8E3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">P-type ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_008495</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000094">
        <property type="protein sequence ID" value="KAJ3224390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015965">
        <property type="entry name" value="tRNA_lig_PDEase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF11">
        <property type="entry name" value="CATION-TRANSPORTING P-TYPE ATPASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08302">
        <property type="entry name" value="tRNA_lig_CPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="314"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="513"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="688"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="712"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1211"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1253"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1304"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1336"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA ligase phosphodiesterase" evidence="13">
        <location>
            <begin position="28"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="12">
        <location>
            <begin position="550"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3224390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1451" mass="162025" checksum="B2283151950E1696" modified="2024-05-29" version="1">MEKLKQENVLKDEDLLKEKLNSTLYPKIAQMVGTEIKFSSDRILFNEKILCLFCSNLEGVESFNKYPHVTLGTISESVKPVESNLLLEKYFTNTIGKDEFQVLRDATCPSIICVTNINLCPPTQKPSCPNGQTLCNDGATCSNDCSTVTDYCACNTEALPNTKYQACSVVSVVLDVDNFIPTERSIGIANQCSKYFNASFAPDGTNVTLINSVGFWAEPLCAGPALDYNYTSQFALSIYGVLGGEIAIIFAWFLYKTFLERNSKNSSVLNTGSNSTIYNEKLGKAAEGKGETVQLKKSPTTLIQPYQNSMVGTFAAFTMVVTSFFLIAWLTSFCVIWHIAATWFVTINLQWENLHNFFKIKSTGFSATSVKILKLKENVIFLDNSSWLVTKVNQFSSLFDNYIGSQYNTFNAKIFKLNQVKYFEFQCTRYVFSEKEDTFAPITIEMANTIGRLRSEYKTGLTTEAAKSVSDLIGPNFISVIVPNLFIAYGEELRSYFYIYQMMCIWVYASFSYYYIGVIQAAVIIISATVKVYVRTTSEKKIKSLAEYKNIVTALRDNEWKSISTTELVSGDIIQISPNSQVPCDCVLLTGDVVVNESGLTGEPLPIRKFPLPANDNEQDVLYNPATSSKKNSLFSGTTVLQADGASNSGYLNQLYGNRAVALVLSTGSSTDKGQLVREILFPTPISFIFDIHLKVVVCLLLIWDATNISSWYYGIFIISEIMSPLIPAALVVGQTVAASRLRSKNIFCINLSRIIVSGKVRIFCFDKTGTLTKEGLEFYGVKNKASDAKEFGEFVESSMSEKVGELMKFGLGTCHAVTSVNGTLVGNPVDIEMFSSTKWSISKVELSEDQHFLNILQPNTKDEKVYKVLARHEFDHARSTMSVIVKDPSTNHFHAFVKGSFEKIMDICAEETIPANYIKTAESYATEGCYVLAMAHKDLGLVETEEALLALKSLERDSIENDVNLLGLILFKNKIRDDTRESIKHLREGGCRNVMITGDNALTGIHIAKAADMLNQNSKIYLAEMVVDEELGGKKKFEEDETLTEIHYKLIWTNIETGKVEVDIDHILKKTDNVELAMTGKAFDRLCDTGEIRKYLLDTRIFARMTPFGKVQCVELFMEHGVTAMCGDGGNDCGALRAAHVGVALSEAEASIVAPFSSKTRSIASCVELLKEGRNALANSFASYKFLILYGTTMVSLEMIQFYYSVICAQYVWIAIDSLITILLSWTVTLAKPAERLSKDRPTARLLGLQTVASIVGQFIINIIFIVVAFVTLYKQPFFKCHEFDASASNIALWWLLGDNYEAAVLGLMVLFQFINSAATVNFGYKFRASWYKNYTLVIVYFLEMAFVCFLVLAGPNPVGCFFRINCGSVNILEKEFNIKPYWEIPQYNNIAGHNIIPEYFRTTLLILGLTNSLLNILFERLVVIGPIGEIFKKKFGVKNKEKEIELIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8E9</accession>
    <name>A0AAD5U8E9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8E9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902554">
        <property type="term" value="C:serine/threonine protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047173">
        <property type="entry name" value="STRAD_A/B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014:SF21">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="83"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="368" mass="42006" checksum="4E6F9CE2E0484812" modified="2024-05-29" version="1">MDEFSFEDVSELGNGLQNEKNSNQNYQSHFVPITFEEKGNKQTMSKHTSFSLSKKSSFNGLLNFKERKLDPYKKYSTNINDYELISDIGGVDDISFLYLAKQKSTGEIIALKYTDLSLSPNFEFMQELIKTSHNCAMLRHNNILPYFLTFEENDRLWTVTLPMECGSCRSIMKNSFSEGFSESVVATILKEILKAMSYLHGKHLIHNDVQADNILIDYNGEIKMTGLRQLINLQQDGWVQSAAFLQVGDNIEWAAPEVMAQNANYCEKADIYSLGITALELAFNKTPFDNWPPLKILCSKLLYPCPAVKAPGKVFSHSFYDLVLRCVHRQPTKRPTVIELLEHPFIQRHAKGPQLIRDTVVKKLAKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8J0</accession>
    <name>A0AAD5U8J0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8J0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037688">
        <property type="entry name" value="ZBBX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28634">
        <property type="entry name" value="ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28634:SF1">
        <property type="entry name" value="ZINC FINGER B-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="341"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="458" mass="52991" checksum="C8B8DD8C0C9D6463" modified="2024-05-29" version="1">MKSANARMFEKRKKTQSQVELEIRKLEKDNKAMEDRLKSLHENLQKQKEQRKNSAYLWKGGQEQKSLNAYAKDVLMAKNFKSRFNGVGQEADRKRAVIESTKNSKSLLERALADFKKSSTNNSQSLEQLTQKPITQQSPQRPSVPMPPTQNIENASNPRARMWKIPVSAQPTVLSTKSLKDESFEDTKNQNNTFSNYNFKPLSDNDPLKFTYTSSLLEHSVDDPVPNKNNSLLSGTFDEAKNQKSFEDALMEWRNGRKSEVDLLIPKAAESENNQYFQENKKEKRINTDFNNNQLANSKFYKVDSNDSKGTETIVEKLPNNNDTILHLITSGKGQNGISYMEKLLLNKLRLEKDLVREKEEREREVFFKKKEELLKKEESLEQFNSGQSNNESNFFSIDTLDVVESSDDEFYFENNKNIKNASIKMEYEKKIELTVKEIETCLEDKGKMRKDVTVIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U911</accession>
    <name>A0AAD5U911_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">U3 small nucleolar RNA-associated protein 25</fullName>
            <shortName evidence="6">U3 snoRNA-associated protein 25</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UTP25</name>
        <name evidence="9" type="ORF">HK099_007541</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Nucleus</location>
            <location evidence="2 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UTP25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000074">
        <property type="protein sequence ID" value="KAJ3224993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U911"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001559">
        <property type="entry name" value="U3 small nucleolar RNA-associated protein 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010678">
        <property type="entry name" value="UTP25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053939">
        <property type="entry name" value="UTP25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053940">
        <property type="entry name" value="UTP25_NTPase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933">
        <property type="entry name" value="ORF PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06862">
        <property type="entry name" value="Utp25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22916">
        <property type="entry name" value="UTP25_NTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP25 NTP hydrolase-like" evidence="8">
        <location>
            <begin position="196"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="UTP25 C-terminal" evidence="7">
        <location>
            <begin position="471"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="652" mass="76093" checksum="8CCB6D26CEBB0487" modified="2024-05-29" version="1">MEIKEVSTLTRKQKRAIKFGANSNSINTVEIENSEDFDFIRENAYDDLLKKIKTKKRRIIDISNNLAEITFNKESFNDNQEIADELSAIDEVDADDTLISGEISHVGGIIACTESGEYKSEKEYCDILNFVIKYHIDTENTNNNSDITFDNIIINPKVKEKWNLINYKNLKDKTLKEAKVPFTPLQDKLFNPIFTYKDVLFQNESEKNKKELRDFYCLHSVNHVMNTRKNILQNNETIKLASASGEDIEEIKDQGFTRPTVLIITPFKETCFEIVQTLIQLSGIKQVENKKRFREDFHGEDETDPTKPLDHQKTFKGNIDDCFRVGLRFNQKSVKIYSDFYTSDIICASPLGLRMVIGDESEGNKDFDFLSSIQIVIVDQCDVLLMQNWEHIEYIFENLNLIPKDSHDCDFSRVRNFYLDGRSKYFRQTILLTRYSAPETNSIFGKTLKNIKGKFKTKLDYNQKKNLSHTNLVLQIPQVFLKFDANNISDLNDSRFNYFIKNVLAQISKSVSKSRTIIFIPSYFDFVRIRNYLKEHNYNFAQLSEYTSPQNISRARLNFFKGNVDLLLITERFHFFRRYHIRGSFQVVFYGLPSRSDFYQEFLNRIDVEKSLGEATSQTLFSKFDLNLLERVCGTARSMKMIEDGKSTFMFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U926</accession>
    <name>A0AAD5U926_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat-containing protein 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LRRC23</name>
        <name evidence="4" type="ORF">HK099_005058</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000038">
        <property type="protein sequence ID" value="KAJ3226350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U926"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849:SF3">
        <property type="entry name" value="LEUCINE RICH REPEAT CONTAINING 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849">
        <property type="entry name" value="LEUCINE RICH REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="391" mass="44461" checksum="C8D282E055E7EFBC" modified="2024-05-29" version="1">MDLKESIETTSNNGFSIGDEPNQSQNDQDSNSIQEKLSSTGFSSGNIPTEAIQVQNDADSILSNQNESFLEGENEETYNNTNHLSQPKKAGVNDFNTKPLTVEMIAQGISLLARTGNGNSHAYTRLELHNLNITSIDVLETFCHLRYLNLSNNSIQNIDVLAPLEYLLSVDLSNNHLHNIPNVLDRRKYLQQANFSKNRITSMNVSNWHLLTWLNLNGKNRLKELCLHAFPSLVHLECRSNLLANNQIEKLGELENLIHLQLLHLRDNKLEVLDNLCEELKELSYLNLRNNLISSLNEIDKLNVLPNLKSLVLLQNPLENIPNYRLEVIMRLPRLEKLDKEGISEEEREEAIQLKLQLAVSKEKEDEAKGDDKDDSSDTYKKGNEDEEADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U997</accession>
    <name>A0AAD5U997_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007087</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000066">
        <property type="protein sequence ID" value="KAJ3225261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U997"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051356">
        <property type="entry name" value="SOX/SOX-like_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789:SF2">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="32"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="32"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="400" mass="45551" checksum="4FDC62E21E6F41E8" modified="2024-05-29" version="1">MQIELNPPMQTLQNEINVSNRRVKKKKITEHINRPPNAFILYRSHFKESQGKGNQRNISKILGQKWKGESDEVKLKYKHLAEKKKNEHKLLYPDYKFQPKKKVVKNEAATLVKTCCLSKTNSNSDSVQNQKYINDTMEYKINTNAANFVNEKISINENQDNITDKCSTTFFNKKSISCTLENTIDCGTTNNPDENKVRYNLENSLNSASVYCAKEKTINNTLENRIDRDIDNKRNDAAYNLKNTIDCRLNSSANKIINPYVKSTIDWRSNNFKEKMIGVQNSDNALVSGCFADKAIVESKIEYTIKREAITVSSNTGIFDNTLENKKSDADAILVNNNISDQNVENAKYKNVTNYRNLCAIPASMVLLGTDKYVVDLKAIKLVSAVTQSFANQEYLSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9C3</accession>
    <name>A0AAD5U9C3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome recycling factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007638</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000076">
        <property type="protein sequence ID" value="KAJ3224918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9C3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="4">
        <location>
            <begin position="94"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="255" mass="29062" checksum="E305D44CE6C2E70B" modified="2024-05-29" version="1">MSSTFTRQFKCISPLSTTITRPFISNTCNNRNVFFHLNSYNVESSNTKFIIRTFAKKKEKNDKTKKLDKSNNEARTPFNTEKYSVSMENALAKFKQELSGFILGRASPSLLDNITVLYKDNKVPFNTVAHTSVLDNQTLMVHIYDEEFIPFVEKAIRNSDRGYNPVKGQHGLLVPIPRVSKEGKDSLLKACSLAGEKSKTIVRKIRSDARSDLKKLKMPSDDSKYYEDIIQVSVDEKISEIDKILTSKQNDIKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9U5</accession>
    <name>A0AAD5U9U5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000050">
        <property type="protein sequence ID" value="KAJ3225860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9U5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc1-like transposase DDE" evidence="1">
        <location>
            <begin position="145"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="345" mass="40564" checksum="048A5502577E499C" modified="2024-05-29" version="1">MPQPSSLSQEYTTIVKRKHHSEQVKLSALYAFRKGDFISVICSKFKISRSTFFYWRRQRSTLKNVKPLKKTGRKERLTPDQQQKLIDFYKKHPTATNEQASAHINNIITRKKVSDEPENYPDDRVLQETREFISALSDIPMKKRVYMDESFVYDNEARSYGRSLRGKRISRQRKRHRKRWWTFYLAIRMEGIVHAPLISTENATLANFWIMLKKFCLHVYGKEMCKNPSKQHYNPEAKATIESKRARILLLPPKGKYFNPIELAFGTIKTNIRNSYTLSKAGGENRPRNDKEVRVKITMNDYNKMKQAVPNHFNAFHYEQLAGQILSLNATFFVSTDSTEYKKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9X3</accession>
    <name>A0AAD5U9X3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9X3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44207:SF1">
        <property type="entry name" value="SURFACE ANTIGEN BSPA-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44207">
        <property type="entry name" value="SURFACE ANTIGEN BSPA-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="32053" checksum="5DC5F198373DEFDB" modified="2024-05-29" version="1">MKILNNPLIDLQQFEFKKLNGLSHSTFFYWAIKNNYFDVFVKLLRKKLDPSIHNNLPIIMACEYGHIDMVNELLKDYRVNPAAQSDRAILEASRYGHLSVVKKLLLDIRVDPSSLNNYAIKEACRFGRAEIVNFLLADPRIDAFDNNSEALCWASQNGHLNCVKELLSSSLITAISTIDSLIWAFTNERYDIIKYLLEDGRVDPSEEDNFCIQQASRKGYVEIVRILLEDHRVDPTANENYALIWSIRLNYDDITELLISDIRLKNYNISGLMQHYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9Z8</accession>
    <name>A0AAD5U9Z8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL3m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MRPL3</name>
        <name evidence="9" type="ORF">HK099_003864</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000026">
        <property type="protein sequence ID" value="KAJ3226912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9Z8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000004">
        <property type="entry name" value="50S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_uL3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="37568" checksum="A1223EC8B6CDFEFC" modified="2024-05-29" version="1">MQILQNSKVNKVLTFHLQKRYLKRILQDKQRKFVADIHEPLTVKYSRIPPQNPLTSPQITANNPVKSNMYKREKFFVTNKVPLPPTFPFSNGRECTPQLNWDVKSERVGLIGKKVGMTNLWDQWGKLRPVTVIQNVYRKYLIQPKEKLMEFEVSENALLPSGFKLNVAHFVPGQYVDVQGITKGKGFQGTMKRHGFGGQPASHGVSLTHRSGGSIGASTSPGRVMKGRKMAGRMGGELRSCQSLEVLKIQPKENLIFVAGPIPGSNGGFLKLRDAVKKLQIQKCFPKEINPNSIPFPSFFGDVEKLPLEILPKFKENKDDLLLDPLLKVVGELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRM8</accession>
    <name>A0AAD5XRM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">STK24</name>
        <name evidence="12" type="ORF">HK099_002400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010001792">
        <property type="protein sequence ID" value="KAJ3201041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRM8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3201041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="170" mass="19049" checksum="19D926E9FF7ADEFD" modified="2024-05-29" version="1">MISPEASDPLNLYELIEKVGEGSYGEIYRAMSKNGPQIVALKIIDLEKTEDDIEDLLTEVDFQAKCDSPYLAKYYGSWMWENKLTISMEFLSGGTLEDLLADFGVAAQMTTGKAYRDTFVGTPLYLAPEIITSEKYDTKVDIWSLGVMGIEIATGFVPRRDQHPMDVNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS01</accession>
    <name>A0AAD5XS01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CASTOR ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001457">
        <property type="protein sequence ID" value="KAJ3203224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS01"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASTOR ACT" evidence="1">
        <location>
            <begin position="54"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="272" mass="31435" checksum="01A54B729CDD3B35" modified="2024-05-29" version="1" fragment="single">MKPIISQLFLSTNKKNTSTLFSITQNADEITLIVDQPFLNNKDLINLDGLYIINDKFKALQVDNLDHNSSSSGNRITNLTEPLASAGLSIFYLSTYQTDFIFVKKKRLTKVIEILKDLKFKIFSDFDDEEILDSNLRFDVDSSSLKNENITTNLTTLKEIVGKDEFFFLDPDLEYFEPETKNFKEIKNVIQIEKELNIVPEVSDVIDSGQKDFYYHHFSQPPIFKQNDFSKGSLKKNVLSKNLELTGLNKETLKKNVLELIQIIFFDENFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS63</accession>
    <name>A0AAD5XS63_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001632">
        <property type="protein sequence ID" value="KAJ3202037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS63"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="269" mass="32252" checksum="F13C81A748E8551B" modified="2024-05-29" version="1">MTHLMKTETNVSHLAVSQQAKNHTSSHRRESKRNAIRINWENEQILQRIEEKKPQYDSLEWLEGRLTQVKYLQNISSFPQRYIEQRKNIEKILGVVEKPKKPFSYQHIQRKQHNEESVRVNMTLVPNPPPLADFLPKETSDKKKYVRKANRVKLTMLEREEEKRKLKETIEEKKNKNNLPALPKIQQKEKVEREKSPIERNDSKKSEIFKKNETFQYNESTLKKNLKIFDSPNKTDAEKKKVVVKHSKTKIENKQEEEKGFFFFTIFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS83</accession>
    <name>A0AAD5XS83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001289">
        <property type="protein sequence ID" value="KAJ3204536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS83"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="371"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="537" mass="62990" checksum="B50F41C7AC817971" modified="2024-05-29" version="1">MERLKVPKNINEKFVFEPLTENEKYEFLRFKEIEFCKKNHLDIYDKYMKMKSIGSEKASIYLAQLMVLYKFKNLVINKSIAQDRRDSLFLREKNGDSPKSKNKNKVSHKKTPSHDDATSLASKRNSDLQAENKIKELENISNLLQQKAEGYRLAEKEKSKYIPEDKLDEYTYKSETVKAIQPEKLVSTPSPILSYEKASTSKGKVKLEPYLNILEEPSKLPLFNNEGKHFDGQKDLIRGITFLIQKRIQRDKFLNQIQILKSEKVAHPSRAYKIDQEIHHLEIKSQDARDVYDREINSLPPKMIDSLTALFSDLFADFKKKVDGENENISLKLQEQEKTFTSSFKTVTENMTLFNERCFGESSDVASKRKVDLVVNEIKSTQEALKAENEKFKKLLESWKIKFNLENEKFDFLKKQNDQFKLEIKHYKEEQLKQEKKILQYEELALNLTKQFENVQDFFTKNIGNLEKRVDSVEKIKTEVIEFLKTREFGNKNAQIRFEDMHHGFCSARSDFSNPENAKKTSLAISHFAKFFNENLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT20</accession>
    <name>A0AAD5XT20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000943">
        <property type="protein sequence ID" value="KAJ3209386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT20"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="76" mass="8639" checksum="1205BEA277552C53" modified="2024-05-29" version="1" fragment="single">FILNNNFDEATLDFFRSCGVVVLDENNNKGSTQIYCEESLTGSSDSEEFFEELSENDSSFSDSDENMEDSDDDHFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTK1</accession>
    <name>A0AAD5XTK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000746">
        <property type="protein sequence ID" value="KAJ3213096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTK1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="430" mass="49730" checksum="F57239FE9910FD6C" modified="2024-05-29" version="1">MKDRITVLESQGPLVAPSAIIRFKKKKLNSPNENVADIVVVEVNELYKEQWNSGSEKKYYVEVNCAFSNSDFNNESEFPLTASKMHKTSDISSKRKEKNELNNLNYDIVSVIESKSFSTDEHIEKLMISLDLKELNEKFAKDVFLNQYQDGNLIDRGTIRKRKGVDSHTWPAEDNVKITYQFRVRAENGLGSSPIGSVVGEKVEVNVYGTNLNQEEQILQGVEKLNPVADEEIINDMSTETNDLEYSFLDDDRYSSQQNSEFNDFSRPGSPFNDSSTIYPTLGQFGESFPVFPDTWHFKLGFGDQFLHNWKNTFYLARALYYTVEMDGKIKLKLHYVGYNPKKHDKEIVISKYIKKVNINNKLEIEKRLKKHFKQFSTDLTAGKDYNNLFEIQEENGWFDSNSEACLYKDVITEFENNFEQGQILVQKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUA6</accession>
    <name>A0AAD5XUA6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000550">
        <property type="protein sequence ID" value="KAJ3215354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUA6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042154092" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="16970" checksum="9D6E4C1546122AF3" modified="2024-05-29" version="1">MKFTSVVLLLSTLISYLLAADGVCQPTGCHGVYTDCRKVARLRGNDCNSTSNDHPYYPCYAALGPSMCQMQADGECAWTVNSTFADCLAKFKASKKINSSDVHFINTTEETSSSVAPIATETSPPVSEGTTASQISSAFMQKSTGFLMIGVLSIILMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUT3</accession>
    <name>A0AAD5XUT3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001619">
        <property type="protein sequence ID" value="KAJ3202124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUT3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040204">
        <property type="entry name" value="UBR7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="206" mass="23709" checksum="B33B6F19473170EB" modified="2024-05-29" version="1" fragment="single">LPSLDSFNDFICKSCVKNNKFLISYKNNEKSLFNFVSLSPAIKRESTALKRKQEVGNTNIPKKLKVEELSSEKFDTPVSTCLLEHAIPATTEEFNLFLNDGWKKELCKCVRCLNIYHDNNLQFLFDEDYELDDEDDESNFDDKQSVVSIEEKGINQLNKIDRQVALDGISAYNDLKSDLMEYLKSFSNKDGNGKVVTKDDIEIFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUX9</accession>
    <name>A0AAD5XUX9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000430">
        <property type="protein sequence ID" value="KAJ3217377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUX9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="288" mass="32812" checksum="97C152DBA0C2AB29" modified="2024-05-29" version="1">MSIKCLWDGCLHKELFNTEKDCYDHLAMQHSSEGKQVCQWKPHFTRPNCLIVCRHRGYFLDHIVSHFSYDLRPIPCQADNCDKLFRNRQDRRRHEINCQYVLDLNKNTSQSNIGMVRASSEGTSINRPKKKRTTTSRHARRGSCSELNFANSGSSTSTYSSSSSNMYSSGSTNTNSSRSTNTNSSRSSNTNSSRSINTNPSRSTNTKSATSSSITLNVYKSVFSKSHPRIFSDEAVQPSTTSSTHSTNQQIQQIQQNQQNQQNQQNQQNQQNQQNQQNQLQDFYTPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV31</accession>
    <name>A0AAD5XV31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000396">
        <property type="protein sequence ID" value="KAJ3218110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV31"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="522" mass="61147" checksum="0D4E5CFC0402161B" modified="2024-05-29" version="1" fragment="single">LYPISFESSLNRFPAELLKELDLISNNDKLYTDEPNLIKVERIFRKISTTDEIHIKDFIDLEKLEIVRICECDEPENEIAQNIIFDITNNDASKNVENFEKVNKLNPICHFSNCRNVDPSHFLVQNFEKSILRIQLINFENNEVECKFISNFDQCSKRIFGEERKQCAELNNVIPSKDCASIECNLEDSIVQIETKKKSHDYEMLQNNLNIEYLRNVKAAETEIKNLKLELKKALFDLKNLNDVNNFSLDTVDKKDQVEIQKTDIHYSSIRLEKENKPHQEVFFNQLDVSNDEVTINSSNSTKVTLKEMSFEPNSFFNREGNLLIDENKISENNIYHTNDVQLNLLLKKIRDLEMIVYQKNEDYNLVSSDLHLQVQNLTTLQQSHKFLQDLNTNLDQKLLDKSIEFSKYATSCENALIEKDSYIKDLTYDFRLREKDFTKKISGLREKNATLAKDSIMQKKIEDVNKKNFCFSLEEAKLMMNNLNITLELEKQNSLSLKKENDVLRQMNETKCSEIEFLSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVF0</accession>
    <name>A0AAD5XVF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Muskelin 1, intracellular mediator containing kelch motif</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MKLN1_1</name>
        <name evidence="3" type="ORF">HK099_000628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001153">
        <property type="protein sequence ID" value="KAJ3206086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVF0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052456">
        <property type="entry name" value="CTLH_complex_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010565">
        <property type="entry name" value="Muskelin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15526">
        <property type="entry name" value="MUSKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15526:SF5">
        <property type="entry name" value="MUSKELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06588">
        <property type="entry name" value="Muskelin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Muskelin N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3206086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="678" mass="78787" checksum="26B10810588745E1" modified="2024-05-29" version="1" fragment="single">SITFGKYHKVHVCNLKEFKIYGGVSLDNLVLLLHAGLRNDTEKETFSLKHLFGNIVFPCLYLKIVPILAHGASFNFSIWYVEVRGTSDTEILEKTYKNYIDYKESEVIRLCLKHFRQRNLLEAFTTLNRNANIPLEDPILTDLHQHLAMNGDFSSSENILVQACSNGLFEEYITSYTYNPLWKRVVLPNNPSMRGGHQMCIDIEGRKIYIFGGWDGHKDLSDFWEFDLTNRCWNCISTDTRKNGGPSPRSCHKICFDSKAKVIYVLGRYVDPENRPNVNLEGDFWSYTTVDKKWTKISSSTAQENGPDLIYDHQMVIDSENQILYSFGGRLVTPDSSVVSYAGLYSYDIKANRWTLLRSDASQGENSSQIKSRIGHSMLHDPETKLLYIFAGQRNKDYLSDFFIYDIKNDIFQEVARDYSVLGGPNAGFTQRATIDLKLGEIYVLSGLMKEKNNPTEMVKSSFWVYNIPHARWSKIYQNDQTENEYWESMQDVQPLPRFAHQMVYDTVTMKQYMFGGNPGDALYPNLRFDDFWELTLERPKPKDILWKAQFQIRQQKFKEMCKNPTEALQYLKTSVYEIVDHSNEKESRMFRNLSWYLFGWNKKNNNMESSVDTKFKYKQNGLVNKFGKISSADGGLLGIESTNEFYDSRIELYEKLLEFFPKSMRQPTENLVDLVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWG3</accession>
    <name>A0AAD5XWG3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000213">
        <property type="protein sequence ID" value="KAJ3221719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWG3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF14">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="2">
        <location>
            <begin position="103"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="544"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="568" mass="65075" checksum="D75A9B11B222DE01" modified="2024-05-29" version="1">MKNDLQSDVEHRESEINKETNIEENNNFLESNDVKPLSAPERATQVYDLVQITYSRFLKLHKGPDDLQSWTPVSNSKSGLIVTKKIINLNSIGSPITTTNNFWQPTTNSTSAALLPLYKGTKVLCGKSVEEVFSVIRSYGCRKKWDDTFEDGRLLEYCGEGVDISSVSLKPYFPLSRRNLTVVNSITRIKNTLNSYTPPNENYKLLNNNSSVVFTSCSIPPDCLTKESWKKLKEFEKSGIRAELIFSAWVLEPLDPYDSETKYPIPSTRVTYYVQMDLGTAYSFFMGSFPSCINGLEKYCNKIPPYVEWPKTGKVEKVSVQKSSNLRVMDTLFDEETGTYTLYCDSSIYCEKAGNLQASATEELLIQFIVNLSVYPNQYEIEWTFDHIKISEKETTDFKPKLRFEIMELDPTLLEEKSENHSTRRSSFSEKALYQPRHLISVYFVNKELKLLEKPDKNVSDGPQAALELKDRFYFEEKSVELKKDGNYIKFKFVIKKSTLPLTSLIDREKFYIFVNGFKTLIKSRNNNDNSNIKVDEKIFEKPSSNLSSSIGSSSTSPINIDKKSIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX31</accession>
    <name>A0AAD5XX31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001559</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000145">
        <property type="protein sequence ID" value="KAJ3223078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX31"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF27">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042271549" description="Copper transport protein" evidence="6">
        <location>
            <begin position="20"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="377" mass="41368" checksum="A9EAD3D6C0A89B7E" modified="2024-05-29" version="1">MKTSLYFKSKILFLSIVAAQNYPDANATADITLLCESMPFMAGCSVMTACSGKSDAFCKPFSILSDICAADMPRMNDCTNYRVRCNITGTGDKNVPANPIALLGNTNDAQCKSELPLPSLPSSKSLSSQVSSICSEMNMSGCEKCKNTGSTYMDCNLLEVYSFLCKSMPDMKQCGEWKSLCAATPTLSFCPSSSGSEESEGPPAMKMFFHSGFADYVLFESKYKKLVLSFILLTFTEWVPRNALQYWLSNLALFVLAIFYEGLSTYLILLEAKWSKFNKAAACYPYRLSTAAGFPSSSSTTFPHSGIRIALTRFLFKFVLTTLGYALMLVTMTFNIAMYFSVVLGFAFGTLIFGGLSKRTRMESTSDPAEEKISACC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX64</accession>
    <name>A0AAD5XX64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000833">
        <property type="protein sequence ID" value="KAJ3211448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX64"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="56" mass="6195" checksum="2AA3B01FDF7CF9DB" modified="2024-05-29" version="1" fragment="single">ITYGASYGAADPQSPENSFNGFVINYMVALFVSIAFFALVRFIGCLIFIIKTPVYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX66</accession>
    <name>A0AAD5XX66_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000143">
        <property type="protein sequence ID" value="KAJ3223116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX66"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="210" mass="24308" checksum="3D84581D1C3E890D" modified="2024-05-29" version="1">MNWIDRYQMMIDISTGMEFLHSKSFPNGGAKQDVFHQDLKSGNIQLYSKNKSLRAKISDFGLSILRDYSFVSENLLRSHYSHENLSVVNLNGWTEEYKAPELQSDTAQFTKLCDVYSFGIILLELITLNQSNSKLVKTLKSSLHLLKFGKLEICNSLGYILEKSLNLNYKLRLPFKNLRILILSEKIEIIKYFSTNDGIFKCKIEYEDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX72</accession>
    <name>A0AAD5XX72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001017</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001263">
        <property type="protein sequence ID" value="KAJ3204809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX72"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="41"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3204809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="287" mass="28225" checksum="D90ED8A9C135C27F" modified="2024-05-29" version="1" fragment="single">DAIATIVGGSDPSPAGVTWGIDRVDQRNLPLNGQYSPSGSGAGITVYVVDTGITAGHPQFEGRASEGAYFAENDAKDGNGHGTHCAGTIASKDYGVAKAAKVVGVKVLGANGSGTNSGVIAGINWVAQQATPGKSVASMSLGGGKSQAVDDAVNSAVAKNIPFAVAAGNSNGVDACNASPAGASGAFTVAASDKNDKKASFSDIGPCVEIVAPGVDITSTWINNGLKTISGTSMATPHVAGGFAALLSQQSFSSAQAAYDALLAKSTPGKITGLPANTANKLLYVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX97</accession>
    <name>A0AAD5XX97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000124">
        <property type="protein sequence ID" value="KAJ3223583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX97"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="204" mass="23747" checksum="D30CA9BD10FAB6F2" modified="2024-05-29" version="1">MGKNAETFQCEQLNCSEPYFDKCVTYKQDYYFRHLDCVTCGKNPVDPLPIAPCIEKSETAVHPLKMCRKGTAETERALQLHYESSRKLDALISITRNRKRTFDKVIINENATFHKSSKSAEQTKLDHTWKAVPASQQMVIYLKVAEYFIAVDDVLSKSMFWALYSQYKPPPWFMLTNQLSPAIFNEEWLAKRRVDKIEVCNDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXL9</accession>
    <name>A0AAD5XXL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxin-19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000701">
        <property type="protein sequence ID" value="KAJ3213530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXL9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033328">
        <property type="term" value="F:peroxisome membrane targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.900">
        <property type="entry name" value="Pex19, mPTS binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006708">
        <property type="entry name" value="Pex19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038322">
        <property type="entry name" value="Pex19_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774:SF2">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04614">
        <property type="entry name" value="Pex19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="34342" checksum="0A59679BC24B9F13" modified="2024-05-29" version="1">MAEVNSKPDDFDEMLDDILDEFDNDTLPSTTTNTQKSFSKEVKSSGNKTSASEVSAMELEEAKFLAELQKNMEEMLKGNLDNNQADEITRDIKEFSKELFKTENKENLDSRNSSNISKNSNNKDNAIDNTTLQSKITDTINLLNDSKSKVTEEFNENKPFLSDMGNMEQMMKDLEGLMSTGEMDSMFNFDKMLQNFISRDLLFEPMKELSLKYPDWLKNNSSKISIEEKKRYTSQAEIITKIVKVYNTTKVPNGEPDEEESKIITDLMQQMQEYGNPPQELMPEINDLDLNNGIPECSIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXX4</accession>
    <name>A0AAD5XXX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004911</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000362">
        <property type="protein sequence ID" value="KAJ3218835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXX4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042041263" evidence="7">
        <location>
            <begin position="24"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="28"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="150"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3218835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="394" mass="40286" checksum="2B7D707A8DA1480D" modified="2024-05-29" version="1">MNFLKPASLLILLSSALVTKSQGLVENQYIVKIKSEVAALTTDVLDSHLSWLDGVLAKHADEFNSQSGVKSAVLHKYENLGTSFTGYAIKASESVLEEIKQNSQVEYVEADSIATALGNPTPTATAIWNLDRIDQRDLPLNGVFRPSSNGDGVTVYVVDTGIYAAHPQFEGRASEGAFFVENDATDGNGHGTHCAGTVAGKDYGVAKKANVVGVKVLGANGSGSFSGVIAGINWVADKAVPGKSVASLSIGGSKSQAVDDAVNGAVAKNILFSVASGGSGNVCNTSPAGASGAFTSAASDINDKKAPFSDVGPCVKIFAPGTNINSTWINSGVKTLSGTSMAAPHVAGGFATLLSQQNFASAQAAYSALLAKSTPGKITGLPPNSPNFLLYVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY55</accession>
    <name>A0AAD5XY55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000832">
        <property type="protein sequence ID" value="KAJ3211470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY55"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="366" mass="42775" checksum="F1ED8B48423FB928" modified="2024-05-29" version="1">MGLKASAKFIKSNKECYYSSIRVQEAIKSINPHIVCLELDRERAPDFQIKNINKNLRSTLHSSIYGSEMSEAFESAKKINAVVKNIDLQSTLFEHHEGDYLNYLHTKYRISNPYGFLKNNMESGVLLKDKFLNDNTTVVGDWVYRFLLFLVFKRFGVLKELNNDELSVAEHASQLRLYQNFYPNSYYHWLELRNAGMVDNFRKIVKATFDLKNVVNEEKDFKFKAINKLRHNSLLKTGEGVENLKIAAVIGKAHLFGMIEIWSEICENENYKKLDLIKGEDDYYKQIIYEKVFSSDHIENEEELNVELKRKASKTKSKFGHEVLIISDLEDDLRKDERERLERNFEKRNNINADSEGKGKTVTKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY70</accession>
    <name>A0AAD5XY70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rab-like protein 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RABL2A</name>
        <name evidence="2" type="ORF">HK099_006341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY70"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="28303" checksum="9ADFAA67DAE512AE" modified="2024-05-29" version="1">MSKITLPGTGGNLEKASDLKIILLGDSAVGKSKLVERFLLNDYHPQQLSTYALTLYRYKCLNPITKKKEITVEIWDTAGQERFQSIHPSYYHLSHCCILCFDVTRKITYKNLEKWYQELVEQRGFNLPLILIANKIDLDPSRAKKVYGFIEKRREERKGDFPVYFCSASDGTNVVSAFRDAIKRAMIFKENGANGDLSDEVLRFIEEESLREDGIFNKNVNEENDMDLNFKELVIDKTNTALDVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYG0</accession>
    <name>A0AAD5XYG0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">LMBR1-like membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006329</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000054">
        <property type="protein sequence ID" value="KAJ3225716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYG0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652:SF0">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36374" checksum="3AD23790630EA989" modified="2024-05-29" version="1">MALDITLIVVSSIFALLIIVAALYFLIYFQHPDDKWRAWFPKFVVVAGLSLSAYNIFLLPLDVANQRGSVTGGIPLGTMTMLTIVFYITTTIMVLVVVPFTVFWYEGLDNDDDVESSSLGKQILYAVKWVIPLDLLMFGGIIALYWFFGSASIKVVNLTGNLQPRGDFINFDYCAQPFTCIKTNTIVNVAVSPFVYVIACVSFLGSVIMSIFGGLGFIALPIDLIEGFIHRTKPISTALYEERKAIIGQKATILHEAGEAIMAEIKGQKQGGIGLNRRQRNLKRKENDFRRDVMIIEIHYQRLEDSYKHAGGDFLLQIGKLVAGIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYL1</accession>
    <name>A0AAD5XYL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_007235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000687">
        <property type="protein sequence ID" value="KAJ3213682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYL1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054080">
        <property type="entry name" value="TPR1-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051350">
        <property type="entry name" value="WD_repeat-ST_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838">
        <property type="entry name" value="WD REPEAT PROTEIN 26-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23627">
        <property type="entry name" value="LisH_WDR26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21889">
        <property type="entry name" value="TPR1-like_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="4">
        <location>
            <begin position="55"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="271"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="313"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="555"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3213682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="583" mass="66250" checksum="216C507C1D70BDE1" modified="2024-05-29" version="1" fragment="single">MKPSSEVSENTFSTKIKENKSINDDLVRLIIQSLETLGFNNAANTLQNEAGVMLELPTVTKFRNLVLDGQWDQSEELLSFLNIPTKDNSIVKFLLRKQKFMELLEKNLINEALKVLRNELQPIVNSTQTRTLHKLSSLIMCNSIEDIKAKEDWLGIEGGSRKVVLEQVRQHIPSSVMIPENRLGYLLDQALEYQKSKCLYHYSSDEQISLLEDHTCNRTDFPGSASHVFEEHSDEVWYVCFSHNGKMLASASKDATAIIWDTINFKPVHVLAGHKEAISHCTWSPNDTKLLTASHDKTLKLWNVENGQHEQTFFKHNEAVSSCSWLPNGQKFISGSVDKFIYLWNLKGDVLYKWENIRCHDLAVSYDGNLMYAISDKKLMMFSLKNLNNIYPTATPTLPVVDGNVTSINSTADNSNFVAPPVFTNNVHNAYPNNVSNNVSTNLHNDLNNHTHTMEAEESNSLAPLLETFMEDHPITSLFLCEDKRYALVTLATQEIHLWDLEEKKIVKRYIGHKQGRFIIRSCFGGVKKGFVLSGSEDSRIYVWHRERGDLLEYLSGHSGCVSCVSWNPKFNMFASASDDHTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYR6</accession>
    <name>A0AAD5XYR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 73</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CCDC42B</name>
        <name evidence="4" type="ORF">HK099_003616</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000239">
        <property type="protein sequence ID" value="KAJ3221289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051147">
        <property type="entry name" value="CFAP_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025252">
        <property type="entry name" value="DUF4200"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13863">
        <property type="entry name" value="DUF4200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4200" evidence="3">
        <location>
            <begin position="40"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="40"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="310" mass="36410" checksum="F5BE37B8CF4C14FD" modified="2024-05-29" version="1">MTSRNVVSMEDYFKANVEKKLFIKMPRHDDDLDLTPATRLLEKRREMLEVENGLKQQKEEFALKMESLAQRREELARKETQLKDSLTKFDKFLKENDAKRTRALKKSLEERKLREQKEGEVNNLRENFTNLTQKKEHQLQIVDTNLSYQRYLESVIETVGEYGEVKDLIARYDTLAATNSELVERARNAQEKTERDRLNFIQSSEEKNNTILNCNNIIAKLQTKLEESQLKSGKWQSEWDHTLENATHKTLLLGQIKMATNNLFTLVKSHLNNRLNNTNDTLSQLDKIQQFICDLNQITSTTMKDINELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYS3</accession>
    <name>A0AAD5XYS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006960</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000638">
        <property type="protein sequence ID" value="KAJ3214242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYS3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051809">
        <property type="entry name" value="Plant_receptor-like_S/T_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27008">
        <property type="entry name" value="OS04G0122200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27008:SF497">
        <property type="entry name" value="OS11G0695000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042017158" description="L domain-like protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3214242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="322" mass="34473" checksum="EA230B92C3022107" modified="2024-05-29" version="1">MRNSPLVFFLLFLISFVTSQALVLPQNSTDCSVLNKWQPQLFAPNCCQVPSNSPFVKLECNIVTQKVISLTMTGNVPTGFVGLNLPQGSSIPAELGLLTGLQKLVIQNYPTQLAASSNVPDIFQNLTYLNHVDLSNNSLSGPIPPSLFVLPELTYMILKFNKFSGSLPSTIILPKIQNLDLQSNAFTGEIPPAISSLTTLTQLTLSQNQFSGQLPPLEGIPQLGNGTITVDNGRLGPTFRVLANCSIAFAGPSICSAGFIPTLCGTASYPCCKADGCKSGAPNLSQPFITVGPIMIIAIIIGTVVVLGLIYICFIFFRGRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYU1</accession>
    <name>A0AAD5XYU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_005610</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the stealth family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000445">
        <property type="protein sequence ID" value="KAJ3217066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYU1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047141">
        <property type="entry name" value="Stealth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021520">
        <property type="entry name" value="Stealth_CR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031357">
        <property type="entry name" value="Stealth_CR3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24045:SF0">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNITS ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11380">
        <property type="entry name" value="Stealth_CR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17102">
        <property type="entry name" value="Stealth_CR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="4">
        <location>
            <begin position="16"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth protein CR2 conserved region 2" evidence="5">
        <location>
            <begin position="396"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Stealth protein CR3 conserved region 3" evidence="6">
        <location>
            <begin position="546"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3217066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="673" mass="77106" checksum="6D0883C8B2E0E08E" modified="2024-05-29" version="1">MSLFKPNQISSKFRAAVLGGSGSVGKPLIKYLIEQQNCEKIILINRKNIAEFEGNSKVEQHVTNMEKLNVETEKIFKSGNSKPDIIYVTMGVGSPSSVTKENLFVVDVNLPTEFAKAASSCGVKHAVLLTSVGSDINAKWSNITKTAAGGGYYVYCKGQVEKNYEDQKFQSLAIFKPGTLIGSPNTPGFFSTLAPKVDWLLPERFRSIHVEDLAGAMVEQSEAQLSSGASSSPYGTKYFEGATLFSSMNISLLPSPKGPNSPSSPLYSPFPHRTSKKVKRSTVAAIVLFVLLIFIWQVKFIHNSFHDKTNIGKGYKKGNIIVSFPNNKKKKKESERLEVVEAVFNETAVSQEEDVWSFAKDCSIIYTWANGSIKEHQELYNYYKYDDKSLRNSFQRFRDNEELKHSLRSYTKNMAWHRGNIFLVVPDGHVPEWINLEHPRLKIINQSTLVDEEDNPTFNTNAIEQNFYKIPGLTDHFIAVNDDIFFGRELHPIDFFTEEKGVNFFFENSALIPNVVYTDHVLESRKTTAKALIRQYDIKDKIYSPKHAPFVYLKEVFPVMKELFAEELKNTSTHKFRHVKDLVTPILHHYTLMNEKKLSHLHYKFLTSKEMENEFYMVPVTENLPKILKNFEDIEKRKPKIFNLNDDYNESYVSYLMKLFLFKMYPEKSPFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ03</accession>
    <name>A0AAD5XZ03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001663</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000015">
        <property type="protein sequence ID" value="KAJ3227512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ03"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023269">
        <property type="entry name" value="RCMT_subfamily_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF16">
        <property type="entry name" value="SAM-DEPENDENT MTASE RSMB_NOP-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02010">
        <property type="entry name" value="RCMT9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="371" mass="42459" checksum="2BC02E48DB4B152A" modified="2024-05-29" version="1">MTEQLHYPDSFLTFLEEESIDIQEFDVLLKLKRYIRIKENSSVSKEDVERDLNTTIDTISYLPNYYSLDSKKNIANSQLYKEGQIFGIDLASGIAVYALDIHRDDHVLDLCCAPGAKLCYIADLQSKHEQDFESTGTVTGVDVCAERMANCKTFIKKYKLDKARLFVADGTKFDVHAPSRTGNSINLNYSEDLNVELIKTNEYLKPFHATKKIRFDKQLKTANLLYDKVLCDVECTHEGSIAHIKKYFDRGWDSFEKKFLDKGRLAGLEDLQRGLINNGFKLLKPGSKNTCSFSKKQNEDIIVWFLKQHKDSAVIEPVPNIDKFPAAPNMFIQEFIAEFPTIKNVVRFTPKYSETSGLFIARIKKTLRSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZB2</accession>
    <name>A0AAD5XZB2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DYNLL1_1</name>
        <name evidence="10" type="synonym">DYNLL1_2</name>
        <name evidence="11" type="ORF">HK099_002360</name>
        <name evidence="10" type="ORF">HK099_004105</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Also a component of the nuclear pore complex.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
            <location evidence="1 9">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000281">
        <property type="protein sequence ID" value="KAJ3220680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JADGJW010000178">
        <property type="protein sequence ID" value="KAJ3222372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZB2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21452">
        <property type="entry name" value="DLC-like_DYNLL1_DYNLL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000001">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019763">
        <property type="entry name" value="Dynein_light_1/2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01239">
        <property type="entry name" value="DYNEIN_LIGHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 9" id="KW-0243">Dynein</keyword>
    <keyword evidence="4 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00055833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3222372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="89" mass="10358" checksum="C26C32E3715DF5B2" modified="2024-05-29" version="1">MSDRKAVIKNADMSEEMQQDAVDCATQAMEKYNIEKDIAAFIKREFDKKYNPTWHAIVGRNFGSYVTHETKHFIYFYLGQIAILLFKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZF9</accession>
    <name>A0AAD5XZF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZF9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041909522" evidence="3">
        <location>
            <begin position="23"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="702"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="382"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="664"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="105"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="494"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="717"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="736"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="753"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3227869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="774" mass="81528" checksum="DB7CFDE6F4B21FFE" modified="2024-05-29" version="1" fragment="single">MKFTSFKFTTILILSLATVSISTPLPANPTQLLNAEKNLVSSHPLFTKRQLTYDAENQKLPAGQEAQKEDEAAVQQDEKKEQQPKENEEVQSAAEPQVKDEQKNEQAAGQQEQQQAAGQQEQQQAAGQQEQKETAGQQEQKEAAGQQEQKEAAGQQEQQEAADQQEQQEAAGQQEQEAAGQQEQKEAAGQQEQEAAGQEEQQKAADQKEQQAENQNVEEAVKQEGAAQKEEEAAAADQKDAEKEQEAAGQDKQGQNQQAAGEANQENAAAAEEKVNENAGAVEEVKAEEKNEEVKAEVQEAKTESQKLAEEAQGVLAADKTAAVEATQKLKEARDALAKDPTNELLKLAAKIADDRAAIADNKVFTDEALISNASDNNGAGVADIKKALALAEEQLKKDLENEATALANKAAADKALADAEAKEDAEEIAKAEQLKAEAEAAAKAAVECAEASKKLVDNANQQAGNGKNVGGNIVDNNNQQNNQAKPEADKAAENNGQAANNNEQAAENNGQAANNNEQAAENNGQAAEGENANNETGGEEVLNKEEKKEIIEKAKTESQTLAEEAQNALAADKAAAVEATQKLKEARDALAKDPTNELLKLAAKIADDRAAIADNKVFTDEALFSNASNNNGAGVADIKKALTLAEEQLKKDLEIEATALANKAAADKALADAQAKNDAAEIAKAEEVKKEADVAAVAATECAQQSKKLVDNKTGKAGKKPKTKKKNKKNKGKTGKNAGNNTNAGNNSGAGNNTGAGNNTGAGNNTGAGNNTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZG1</accession>
    <name>A0AAD5XZG1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002116</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000168">
        <property type="protein sequence ID" value="KAJ3222604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZG1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="50732" checksum="C7DFD4B6ECF1442D" modified="2024-05-29" version="1">MSVVSNFNSNANVTNIQRNPTLELTKSTMQMNEDENLMMQISIENIALPNLRDSTSSAVSSEQEDPNSKSQIQWLKEYGHLENIQGNIRNNGVLKKNITFVDELPIKRNNQNYIKSINNLENDTASANNKGSGRKFWSKVKDDSTNATFHGGCLSNRFNLFFFVGSRSRHFLRPYISEFIGTFLLTFFGTGAVAASVLTDSMGSSWQVASVWGYGVAIAIYVSRHHSGAHLNPAITVAFSLYTDFHWRVALGYIFVQNLGGVCAGLVNYWVYERLLENFETNHKIIRGQEGSQRSAAVFGEYYPNPNVFISTQAENKVIVTANDALLAEALGTAILTFTIFSLTDQNNKAVIKGMAPLFIGFTVAILTVLFSPLSQAGFNPARDFGPRIVAYFAGWNSVAIPGPQRGFWVFIVGPIIGAIIGGGLYFFSLRLDDRGIASRMGRKDLRDLKTNKKILPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0V6</accession>
    <name>A0AAD5Y0V6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000056">
        <property type="protein sequence ID" value="KAJ3225632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22408">
        <property type="entry name" value="KH-I_Vigilin_rpt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057778">
        <property type="entry name" value="KH_Vigilin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24668">
        <property type="entry name" value="KH_Vigilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="131"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="208"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="291"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="374"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="443"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="524"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="614"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="800"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="946"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1045"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1140"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="1198"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="30"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1276"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1463"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1542"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1276"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1326"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1388"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1417"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1548"/>
            <end position="1559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1571" mass="172501" checksum="678D8ECF1D6685D7" modified="2024-05-29" version="1">MDHSNNHNIGQQQQQPLNLLTKLQNRLHPDSTHDYLISPPSHDLDFSPKPPSPTLNSQIPVQQQIERQQSTSENSTSRLDLKNEDAFPSLAPSTHKVSTTSWAKPAVLSAGKSGKIIGSAAVTAAKKKVPNQVTDRFEIPSHAQAKHQSQLGAKSGAPGDICRGISSRTGTNIDISSSKMSGNLTVIISGTANDVKQAKREVQNALCKQITVTLNVPSCVRPHILGAGGKTLKALIARTMTKINIPKADTNKSSEEEEDSFEEQPITIIGDYEGVETAKTEIEAIVTSRTSRSNSKLIIDRQFHPFIAGVGGSTVQLVMLETNTKIHVPPLFLSKDSEKSQGKNLNEIVIIGDRKDIAVAAEKLNNIYEQVRQSTNTLVVSIKKRSHKFVIGLKGSGLQNVFAETGCFVEMPPASDSSDVVTIRGPSQNLSKALNLVMEMATSTRIAEIDIPSLLSKSTDPNLFIKYLYSKHRATLKNFESTYSATIIPPQENANILEIQSKTDTGCQSMKEELQKFIKELSTDYFFSVVEIPRNLHKFVIGKGGANIVKLKAMPECGGRILDIIVPQESDESDEVIIVAKLNKEAAKSSQTEVMNLIGKVHEQLISFATNLAEYGVKNIIVDAKYHGKLIGSKGEKLKELLGPLDGSVVVKFQSSKGKETKAEESNDPHTVIVKGPLKEAEEVADKILKVVAEWRHNEVMNSFEEKIKVPKNLGKKLLNGGGNDTGSGIYWLIKSIKEYITANDKHHQYSEKDLSGNLALKADLDESNSNHDIIHVVGPKHVVSAARVVLEERSVKIADIVEVEVKIFDEVSSIARKELKFGNLEEIQSRVRSRIIGKGGKAINKFSQKHDISVKFQSKRSEEDDEENDDQGTVKLKGIKGNVERAKKDLLELVEFEETHDVRVDFNDVLGENDEELIETVVEGSKENCETIKRTILNQVDDQASIDTRTVQIPSYMHKQIIGPSGSRIKKIIDQFGGNDKIKIQFPAANHKGSKSANNFEQDAVIIQAHKDLLPEIEEQIKNLVSSVYAGQDENDETILDESSIVEQVISIPRSDIGQVIDRGGRNLKDLMSRFGVNIWISDVDSKDADVPVSVVRIVSTPGKEEEVENAKNEILSKLRVSKHITLPTEIVECLNSSEKDIEKVFLQEILKRISSESGVSADLNNSSDEVILRGESKNVKNASKEFEAILKKMAKLSVTRQVKVASSLSPHVIGRNGFTINKIRNDSGCLISIIKGKASNVDLIVIKGTEKSSSVACAAIEKIIKAQEIHQQRDQERAAAAEDALKKKETSSLGKNSPARIDDEDFSSNDGSDQLRSIPGLTNKKGTSQRNVRSAPQTVVQSEHVPIRTSVSSFKKEEQDWQQVKPRYSTKGAEDGDVGEEALEKSKKKNKKKNKKSKATSESSQVGEKIVEEIPVTTPKPSSSSPHNKKEADALTPAALKKPLQQDYVAKKQSATANIAQPDKVPKSEITKAVPPTVTESKKIISSIEKVSLPFTPKVDDWQTVETKKVKPTKAGGPQQPVVQTANSVVTDSIFEVLEPEVASSGKKKRKNKKKKIQTNGVSNEDEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1D6</accession>
    <name>A0AAD5Y1D6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxyisobutyrate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002465</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000181">
        <property type="protein sequence ID" value="KAJ3222315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1D6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF8">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE NADP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="6">
        <location>
            <begin position="167"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="33200" checksum="6D00D94CAE69037E" modified="2024-05-29" version="1">MGYPMAKNLILAGYNLAVFDVDLSRGQLLQSETVAKLGSVELFSSAKDIFSKQLNITTLITVLPNDKILKSVLIGNDNEGGILELLLPNSQHISCSTISPQTARELHQAHKKRNIGYVASPIFARPDGMAAGMASLVLSGDEEAVLRATEILKSTASVIKTFGNDPGAANVVKLCGNYLIGSAILSLWVAWGLGVSNGVDRVEAIKFYTSTFFDCAIYKGYGQRVSERDHKAGGFALELGLKDMTLVRDTAYLSNTPMPFLSVLVDRFLGEKAKGRSSLDWSAIGLGVSELSGVNVCKYVEACSRGEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1W3</accession>
    <name>A0AAD5Y1W3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Gamma-aminobutyric acid type B receptor subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GABBR2_3</name>
        <name evidence="12" type="ORF">HK099_008502</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000094">
        <property type="protein sequence ID" value="KAJ3224397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1W3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042141714" evidence="10">
        <location>
            <begin position="21"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="576"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="416"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="803" mass="90250" checksum="FD9693611671D780" modified="2024-05-29" version="1">MPFQKYLFLAFILIVNKAFAELEFTIAAISQKSTEALGEFATQLIWATEQAVHDLNNLTDPIIPNVKFNFQHKDSYLSKKESIKAVRDLMTQPNQTTSPIIGIVGEIFSSISGVISLSSQVYKVMQCSGASSSPDLSDKDSYSNFFRTVPSDVHHLGQVLQTETKRLNITIKARYSYSETGSDMNNCVKTVQVSGAKVIVILGYIGDVILFFKEARKLNMINKNYVYIGSDGTSIDSLANLDLKDFDGYFYLSPKTYANNDFYRNLKQNFLDSSKNQSSNGTLDESSFIDRTGLYYDCVFSLVHAFKNLRDMESLSLDTFSSSDLNSPKINLTHVERVNFTGVSGDITFDKFGDPRSVPYLVTNIQDNQKLVIGFIDGKSGIFTQNENFIPKFNENSTIIPFDSNGELKVKWNDPGPLVVLSIYIMGFCLTVVSTFILYIKRSYSAVKCLQASFLQLISLGLLMIWSSILGFVFESTAFTCSYQQWSLYVGIGTILGAVLVKVFRIWQIFANTVCVKANNGYLRNGVVLLYAGLIILGEVIILSTFTVIDPPLPTKVETLSYFYYECLSHNSETQITFNIILLGYNATLLLMVTVLAYKTRNVRMIYRESSYIAQMSLNIALCAMITNSKTYHKLVCLIGPVVLSLLLESYATKVDDSKTKSHVLSSNIDDDNSLESAATNRYQSSARGNNQENHKKTSFMLATKNLKHFVLSNWKKSLVIIKKRFLLIYMLNEVKKSNNSKFEPSSEGICIIIAEMNIKRNELPYCLNVFTEKISILIQCKDDKECDLVFYSLEKNGASVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2P5</accession>
    <name>A0AAD5Y2P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005887</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2P5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="103" mass="12125" checksum="D4A40C088667A65D" modified="2024-05-29" version="1" fragment="single">VKDDSRSVKEEVYKVLKKMKSYLTKNHKFTNDKDSGIKKRDRLDDTIFSQFCLKVLKLDLEELRERSLAEGLYDEALRVDVEFLVREDDLINDGNNVLTCYDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2Q5</accession>
    <name>A0AAD5Y2Q5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2Q5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="123" mass="14184" checksum="EC526AE69D2E2A03" modified="2024-05-29" version="1">MFKNFHRVTQKIPQRSFINANLKEVKVNVISIIGNLTKEPTWRTFGVPQENGVERGSWNFIIATPKSFKKPASDDVRDKVMFLKENIQLLRSPPQARYGSNETENTPNNNKEMDPTQSKLNDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3C2</accession>
    <name>A0AAD5Y3C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="5 17">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">HK099_005150</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 17">
            <text>2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 17">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the ALAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="5 17"/>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3C2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000048">
        <property type="entry name" value="Delta-aminolevulinic acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006762">
        <property type="entry name" value="PRK09283.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458:SF0">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="10 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 17" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="14">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="14">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>5-aminolevulinate</name>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3226319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="348" mass="38191" checksum="966968DAF1C6CE95" modified="2024-05-29" version="1">MKTNSIPTTSYLHSSFGHPVLRSWSELNTNLTKESLIYPLFITDDANAVEEIKSLPDVYRYGVNKLEEVLTPLVRKGLKSVILFGVPKTAKKDNFGTSATSEANPVLPAIRLLRKKFSELLICCDVCLCAYTDHGHCGILKDGELENIASIQRLAEVAGTYALAGAHVVAPSDMMDGRILAIKNELIRIGKGSKTALMSYSAKFASSFYGPFRDAAESGVKGGGDRKCYQLPVGSRGLARRALQRDMAEGADMVMVKPGGPYLDIIRDGKVTGKLTRELCTNYPVAVYQVSGEYAMLWHGAKNGVFDLKVGVLESLTSFYRAGANVIITYYTPKILEWIDERNYPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3K3</accession>
    <name>A0AAD5Y3K3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">mRNA 3'-end-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_003966</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the CPSF4/YTH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3K3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="13">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="13">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="13">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="13">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="14">
        <location>
            <begin position="205"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU369008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3226854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="224" mass="25800" checksum="CD4A32E1367FFA2F" modified="2024-05-29" version="1">MNQISLRNFSDFNLIDSSYIFEFENFIKNDLKIKIEKQQIQPVCQAYLRGNCLKGNNCPNKHTFEKSVVCKHYLRGLCKKGEQCEFLHEYNMKKMPEYLHIDPNLKIKDCPWYARGFCKHGGHCKNKHVRMAVCQLYLTGFCPKGLDCEKGHPKYELPPSEEENHSNSHFQQGAATSGTSGGNNFGKFQQFNGEFVKKDLKDVVCFKCGEKGHFATVCPKRRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSC6</accession>
    <name>A0AAD5TSC6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002244">
        <property type="protein sequence ID" value="KAJ3198868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSC6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="103" mass="11883" checksum="4935074AA8308F56" modified="2024-05-29" version="1" fragment="single">MQNIIEIYNDNNCTDKISPLDKTCYDEYLSIKVFETKTGNKFSFCPEGDINFSLPAFNGSCYDLENYLSFNQSIDQRFKDIGCQNLKCTMMFVSNIITIDNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSH5</accession>
    <name>A0AAD5TSH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002138">
        <property type="protein sequence ID" value="KAJ3199321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSH5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="291" mass="33214" checksum="4BF868EC4FFE1D14" modified="2024-05-29" version="1">MIQLDDSTLLRDLLIPGTHDSGATEADVGFPWSNSVATQYWRIHEQLEHGIRYLDFRVAANCIKVPLDGAPCSQDGLWLWHGDIPLINYKLIRIEDAFNQVVTFLKRNPSETILMRIKKENNFGYGFDLVTALQEFIFEKGYQDFFVRPKDAKINTGIGKMRGKIFPWWDAENGDESDYGAKYSDLVDAPEHDLGKFDNLDQFEEFIRGKFEESKTVDVSKRFFHISASGHDSGIPNLAKFSDRSMNVLLSLVRDSGNYPKQGVISMDIKQDKTERADKIINLLIKKNLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSR1</accession>
    <name>A0AAD5TSR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002256">
        <property type="protein sequence ID" value="KAJ3198819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSR1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="151" mass="17930" checksum="C60CF5A8F78F07D3" modified="2024-05-29" version="1">MSKKEFENQSFIINSNKNINFNNLNENFDQLQENGHVKEGFTFSKGEFNVTLEELRESYSKVCRNFSNSESDNVNEEIYYRDCEDNEYYELDSEFSDESSEADCEEEDEYQSNLNSTFDSIILNSVKAQFLFCEGLLRRLWNVYQLVLKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT09</accession>
    <name>A0AAD5TT09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001965">
        <property type="protein sequence ID" value="KAJ3200125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT09"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="52" mass="5609" checksum="ADB8FB52EAF720EB" modified="2024-05-29" version="1" fragment="single">MEETLITTINNLNKIMGDGGMIVSVVTENETHSLTFGTVDGQHPVDTSSLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT82</accession>
    <name>A0AAD5TT82_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_002769</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001949">
        <property type="protein sequence ID" value="KAJ3200211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT82"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3200211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="75" mass="8260" checksum="64DE154B1081D486" modified="2024-05-29" version="1" fragment="single">MHLMMNMLVLQSFGPLIFETLLNSKELFLAFYLSAGITSSTLYQLVSTIFYKTGFRPSLLMCPSLGASGAIYGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTD9</accession>
    <name>A0AAD5TTD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit beta</fullName>
            <ecNumber evidence="14">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ATP2_1</name>
        <name evidence="16" type="ORF">HK099_002041</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="14"/>
    <dbReference type="EMBL" id="JADGJW010001642">
        <property type="protein sequence ID" value="KAJ3201975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTD9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01133">
        <property type="entry name" value="F1-ATPase_beta_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000001">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.170:FF:000004">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000026">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039072">
        <property type="entry name" value="ATPase_subunit_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="151"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3201975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="480" mass="51875" checksum="8377C4FE92A8504E" modified="2024-05-29" version="1" fragment="single">RSQSSSASVGSTGEVRSVIGAVVDVQFDAGKLPPILNALEVQQHDIRLVLEVSQHLGENTVRCIAMDGTEGLVRGQKVLDTGSPICVPVGPECLGRIINVIGEPVDERGPIKTKQVASIHADPPTFVDQSTVPELLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVLITELINNIAKGHGGYSVFCGVGERTREGNDLYHEMQHGGVINLKGESKAVLVYGQMNEPPGARARVALTGLTIAEYFRDKEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGGMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRGIAELGIYPAVDPLDSKSRILDPRIVGDEHYEIATSVQKILQNYKSLQDIIAILGMDELSEEDKLTVERARKIQKFMSQPFDTAFVFTGYEGRYVKLLDTIRSFKEILDGKHDDLPEAAFYMVGDVEEVRRKGEQIAKETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTI5</accession>
    <name>A0AAD5TTI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001702">
        <property type="protein sequence ID" value="KAJ3201598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTI5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34204">
        <property type="entry name" value="RNA-BINDING ASCH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34204:SF2">
        <property type="entry name" value="RNA-BINDING ASCH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="155" mass="18554" checksum="ACAB5ED86222ACF5" modified="2024-05-29" version="1">MENLIIPWSENPTEEELKYKANVYFVRTIGTCFDIPIPTECELRSSFQNQPNPNSNLSVGARALTKHFVRKTKDKKVKSVNEKHQFWQEPIGSEKNKNLIALQHLEYFLTNSTWKNLHIITNQTTVFEMRVKEMYGMRWFFLDEKWQFRGYLEPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTS6</accession>
    <name>A0AAD5TTS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC transporter substrate-binding protein PnrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001463">
        <property type="protein sequence ID" value="KAJ3203184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="ABC transporter substrate-binding protein PnrA-like" evidence="2">
        <location>
            <begin position="37"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3203184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="135" mass="15024" checksum="811909786FB343E2" modified="2024-05-29" version="1">MDINYKTSYDISFLGFGVENILHIIIHSDSAAMAEFVPEAYKQLNFTLIDPTLPPTQYPNLATIYFAVGYLEGAVAGLMTETNNVAIIADYPKSVQRRYVNGFKQGVLAVCPICNIHHLYLKAFPSKNNDFITGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTS7</accession>
    <name>A0AAD5TTS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001622">
        <property type="protein sequence ID" value="KAJ3202103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTS7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="529" mass="59729" checksum="667C43F62D8F7389" modified="2024-05-29" version="1">MISSTIDRKSKVDSIQKQFPNIDLKSSSIKETKVRKTGLFAKIVNQGDFEAEKHFYPRVLNAQVHPLVASFFSLGNERILARYTHLNPQVNQETLKELLTYKPKYFQWAGSDLFNVTTANGQRQMIIVETNSCPSGQKSMPLLQDNDEHGGYGVVIDVAFKNLLKSTKVTGDLAVVCDKNMMEASGYAAVLSEATGEKVWLAEFFEEDPEPPVKWIDNVMFVKDKSNEWHQIRACFRYVTQKPWNRFPVNPRTVVLNSIVSCLAGGRNKMMAARAYEFLNAEIIDSGLQIRIPETIRNVSKSEIPLWFDSMGGHAVVKVPYSNAGQGVYTITNKNELADFMAKNHHYDKFIVQSLVGNASWSSVTRAGKFYHVGTMPNKKNHTFVSDLRMMVSANESGFTPVACYARKARKPLLRYLDDDPSVTSWEMLGTNLSVKHEDGSWSTEAQRLLLMDRKDFNLLGIGIDDLIDAYIQTVLSIIAIDKMSKRLMKENETGKVSFDLELFEALNPDPTLIDELMEKTLIENGHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV43</accession>
    <name>A0AAD5TV43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001720">
        <property type="protein sequence ID" value="KAJ3201477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV43"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="107"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="290" mass="33996" checksum="B4ED47E82CFA1BEA" modified="2024-05-29" version="1" fragment="single">MIDPDLNFKKVIPASNLKNFNSELLNNFDFERKHKNERELNDINKIVTNKEYENGFFLKEIEILKQKAKVTLKEKIELQNQLAEECVVSDKLKQEFLEQENALLIQLGVLKAEKSEYKKKVLKLEKELQKIDISIFQKKYNFNTQLKSKSNDIKELNEEILKLKSLNNQCNQKLMEQNQKLDQVIKENIELKQINSKLMEDSETYNLSIEESIYTHLNDITVPSKKMSELVKSTEAINVLIEDEEDLKLKNEMLADQVEALTTYVSKILSKVCKDERLEKALTNCIFEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVG7</accession>
    <name>A0AAD5TVG7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Glycosyltransferase family 71 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_003212</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002135">
        <property type="protein sequence ID" value="KAJ3199336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVG7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000033">
        <property type="term" value="F:alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392:SF1">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3199336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="36043" checksum="2806B80A58872AD7" modified="2024-05-29" version="1" fragment="single">EKKFEITTLDFKKNLGLISKQERALLETKLDKKNLIQLGENLRLFKKYFDAKLLIKEEKKDSKFNEFNVIYSKLENKLFSWFLKKNNNSNFISLHQSFREKGIVMCIGDKGYPHLAYTTIMMVREVFNCDLPFELFYLGESDLSLKNKKKFESIVGVTLINLETMLDNNILKLKGYDMKPFACLFSSFKEVLLMDSDTVFLKSPLTFFLQSNYIKTGTLFFHDRQVKDFHFGIFKTSNFIKSYLPKTIPKAVLNLNILNWKTDHEQESGVVLIDKSKHLVGLLASCSLFQEGYRDILYYYTPGDKETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW89</accession>
    <name>A0AAD5TW89_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Superoxide dismutase</fullName>
            <ecNumber evidence="2 7">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002066</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 7"/>
    <dbReference type="EMBL" id="JADGJW010001657">
        <property type="protein sequence ID" value="KAJ3201872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW89"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43595:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="8">
        <location>
            <begin position="4"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="9">
        <location>
            <begin position="120"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3201872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="26879" checksum="24DBF03E3F374FF7" modified="2024-05-29" version="1">MLVLPVLPYAYDDLEPFIDKQTMELHHLKHHQGYTDIANSALNDILHSENPSEFVSKNRYDMLKLLRAIAKSDAESVESTFKGKQTILRNNGGGFYNHSVYWKNMRPNPQKEVLLPKKDSAFTAQVTKDFGSVKDMVNECKHSCKAIFGSGWVFLVRDSKDKCLKLVKTANQDIPEFSLPDSGNLDILIAIDVWEHAYYIKYNNRRMEYVDAFFCVINWEEVECRFERVKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWS4</accession>
    <name>A0AAD5TWS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bud site selection protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BUD6</name>
        <name evidence="3" type="ORF">HK099_000364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001083">
        <property type="protein sequence ID" value="KAJ3207038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWS4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005519">
        <property type="term" value="F:cytoskeletal regulatory protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1540">
        <property type="entry name" value="Actin interacting protein 3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022782">
        <property type="entry name" value="AIP3-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005613">
        <property type="entry name" value="AIP3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051825">
        <property type="entry name" value="SRCIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741:SF10">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN CG32809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741">
        <property type="entry name" value="P140CAP/SNIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03915">
        <property type="entry name" value="AIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00806">
        <property type="entry name" value="AIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Actin interacting protein 3 C-terminal" evidence="2">
        <location>
            <begin position="199"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3207038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="673" mass="77527" checksum="37498EE40C05D78A" modified="2024-05-29" version="1">MNHFLQIMSLSETIPNCVLSCKNYLMNIDKKQNTIPNIIQNIQNVLTQNIDESDSTINNLKEILLILEGINDPKIVVQRAIEVLSAVTYQEENQLYPPSIASEIFNDTSSKCENMDFEREGNNWSNYLELFTFQFIVTFFIQYMDVIKPIFISNLVKKRNFEIKAVILENIEGIRIKNGNAGNKMLHSFNSVSSVGLGLEVSHHNSPLTTGANVIAPPTLDVDNVFLRNSKEKDFFRIEDFNFSEVNDQDILILSIPASNPYEWMKKYMDTAVLQLTKEITDLKKAVLNEGNTATEYSSPRYPKIVNSSNDSRRTSVNERSKFHLSESRRASFTSSVSALKGIKQPSSAQIYSMLKNITPNNKNAKLQTTIKKYSGIVGGLRKELAVCKQFYKTCQQDINQVLSDLITQTAEVRKSLIEEDIGNRKLLVSGKKRIEEQSSQLVTKVQDLQDIINELKLDVTVRKCRPSSQEMEYLIKEIISTKDEIDEFSEFVEEVRPCWKSVWEFELQSIVKEQNFLKEQENLTEDFKDDIFSIIEVFETLKTLIELQLKSSKTSSEIKLEVLTDSDEFGEGVRNVLTEIQLSPYDYEKDSKKRLRALERNLKIKRFEKATRVNIFELELRFVTLLNFKKSILNFMFLSSKFVNEKKLKQTGGIEEVERKLKGNNIFLKTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXQ2</accession>
    <name>A0AAD5TXQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001782">
        <property type="protein sequence ID" value="KAJ3201108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXQ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="131" mass="14146" checksum="BC5EB21906369191" modified="2024-05-29" version="1" fragment="single">MDNLETGVGGGEAVKSFSKKNYGDPSPISTTDTPNKSYILRKGDRNKNYGDPDTTVEKRNRNKESKYGGSNYGSSSSTIFDDEKSSIVSETPPIIPVLLKREVSFANEIKFAGLAANAEVAKPKLPLSKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYB6</accession>
    <name>A0AAD5TYB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005784</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MUB1/samB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000467">
        <property type="protein sequence ID" value="KAJ3216636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYB6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990304">
        <property type="term" value="C:MUB1-RAD6-UBR2 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051664">
        <property type="entry name" value="MYND-type_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47442">
        <property type="entry name" value="MYND-TYPE ZINC FINGER PROTEIN MUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47442:SF1">
        <property type="entry name" value="MYND-TYPE ZINC FINGER PROTEIN MUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="9">
        <location>
            <begin position="520"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="252"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="363"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="256"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="370"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3216636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="628" mass="69811" checksum="C4B846F552E924D1" modified="2024-05-29" version="1">MNLLSGAKQAAMVISLNQYDKRALTCTDLLPLTNSLHNLCYMISASTLRISYILATDGGLELIIQIMNKLTSRDTLPRLAYSAALSCLTNVAVRGNQRLRRRLVEAGVIKVIVDLLQKVVEVLKVVKATNNSFSDEPMHPQHVQQQALFMHLQNQTTLNTQMQSPFIIDTNEDLNGVLNDNNETANSNPVQNLLNNNNFIATAAESDAMNSGSTLVENANSYSIFTSTNNANNGSSSPTQAQQREILTANDRRQILDSNQNIPSTSDSDNESLNTRSSNLFSSGQNEQESASRFTFNNINNDNNIPLQRPLHSRADFLNRTLGTANFETRDSEVDFATTEQENFNFASHATIDVAIEVGNDVRSGEPMEQSSDVQSNSVDNNMNDVRSGGDSGSSESTSDSHFHEILYRVEDILQAIKIIAYLSKYPTIRQDLHAYSGKNVFELVEIFTGPSNLVEIRKWATVCMRNAFKRDTTTASSNTNFGTFGSAMSNYSSSIMNADILDSTDSSSSCGTNLRRCGFLKCGKVEKTPRQFSKCSRCRRITYCCKLCQRNAWPLHKHWCLKYEAHGNEQQLQNELPQNNENLQEQQEEKDVNLDDEGDSTTAENVSDEVIMGEIAALNDDVLMTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYV2</accession>
    <name>A0AAD5TYV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000462">
        <property type="protein sequence ID" value="KAJ3216760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYV2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="51246" checksum="28591989F4F46E24" modified="2024-05-29" version="1">MIYPKNSLKLSKVPVTTPTTQPSKCLWLNCSKTFDTELETYNHFIKCHCKKGVQKCLWSGRGKICNLTLRHKGDIKSHAVVHFNDIKPIQCAFCGDRMKNRQSLHRHKLVCKKTLTPTVEITVTEPSKNDSTDDTICITIEDNEVKKTNLGEGSNYLPSPEISNPPSPLFANVTVSMYPSGTLTPSFNNITPMSSPMLNTQSLSLNNQCLSPMLNTQCLSSPMINTQCLSTPMLNSQCLSSPMLSTQCLSSPMLNTQCLTSPVVNTQWFSSPMLNTQCLNTQLNNLSFTNPHCMCSPLVDTQGLLATSTSLFNETPKSPYDNQFLSPVNSNNPYTQNSIFHDDNDFLLALLNTDISNIEDTTPPSTTPTVNNELNIFDDLDKVVQQEYNVLDELNKLVHKSPNLNESKLDIFTAPTSPSQNSEAMFAPLSENPLSENVGTKNTEYQDVLPFIDQFMMMEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ05</accession>
    <name>A0AAD5TZ05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_007413</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000716">
        <property type="protein sequence ID" value="KAJ3213382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ05"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="10">
        <location>
            <begin position="53"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="343"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3213382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="434" mass="49454" checksum="79CBC8B9F0B93B98" modified="2024-05-29" version="1">MQHNQNPLTIATDQLHEQQQPSINTSMTGISNGSAISQSPVASPKKSPNVGKSGCLFVHKLHNMVFDKNYQTLITWNFHGTAFTVMNVDKFAKEVLPKHFKHNNFSSFVRQLNMYAFLKTNKSARGSRTAAEHQIWEFSHPKFLRDKPALLDEIKSTKSRKILELDKNSASNNSQGIQQLQNQLVQAISTIQSMQEQFTEVVRELNDLKRKGALHQMMMTNVLMFMKENKMNLQPQQFSGLEAAMKDPTFASIEQDLEIKKTNQQNDGNSNFGKIDFDFQSFDKILPLESKGDTMPRQHSNILFQDQQQRQMNSKFQPPAVQLFSFPSNTSPTQVNQHHTNFNNIQQKPSNHPQSSPYHTPIQSPYNAPQHSPYFAANHSPYVPPNQSPYNKPSQSPYNTPNQTVLNNSSSQVQFVSQQQINENILRSNLNPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ09</accession>
    <name>A0AAD5TZ09_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit D</fullName>
            <shortName evidence="5">eIF3d</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">EIF3-S7</name>
        <name evidence="7" type="ORF">HK099_006328</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000539">
        <property type="protein sequence ID" value="KAJ3215501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ09"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098808">
        <property type="term" value="F:mRNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002191">
        <property type="term" value="P:cap-dependent translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03003">
        <property type="entry name" value="eIF3d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007783">
        <property type="entry name" value="eIF3d"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12399:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05091">
        <property type="entry name" value="eIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016281">
        <property type="entry name" value="EIF-3_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3215501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="569" mass="64458" checksum="258ED2BAF35A997F" modified="2024-05-29" version="1">MVAKKPSKEIVLPSFKLPVIDVNPNGFGPCNLPVELSSVPYAPYSKSERVGKVADWTAPTEGQYRDQEGVTQTRRKPRFGNEPSFGAGSAGLFMYQHSTEEEASFSVVDRATSTRKTTGFKTQKPRVSKHANAADRRLMTTDHKKRRYGYNDKPQRIRDSSVTVAPDWRIIEEIDFNRLNKLFFDVDEPEDIAVTSQLKYLDQKVYDRVSTKNDKILHHVEHPIPNFTSSDDPILQKFAANVTGATVFATDAILATLMCASRSVYSWDLVIVKEGNKIFIDKRYDALFVNENAADPPMESTDDNPNTPGNLSSEATEINRDFARQILKEDEKYIFKDSTELAGDDQPIGAYRYRKWDLGDDITLIARTQIDAAIHQPGFNSQQESEFLEAKKSAHNAQETMFVTVKALNEFDYKAPGAGGAPDWRQKLDSQRGAVMASEMKNNGNKLAKWTVESILSGADQIRLGFVSRVHTRDPKRHTVLGTTFFKPKEFANQINLNMNNAWGILRTIVDLCLKRLSDGKFVLVKDPNKVNFNLIQYFYFFVQTLLRLYQVPLNTFNSDNEDKEEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ53</accession>
    <name>A0AAD5TZ53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysine-specific demethylase 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">KDM8</name>
        <name evidence="2" type="ORF">HK099_005389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000416">
        <property type="protein sequence ID" value="KAJ3217644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ53"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="229"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="377" mass="43977" checksum="F4C9FE33DEB0047A" modified="2024-05-29" version="1">MKKCSGSYIRACFIKSLYWICLSENGNTNWTLPVQDGLSGDLELQCLRLAIKELDLSILISGSPLLKFETHDLIHKLEQLIEKKEGLRSLNKNSVKNIFSELINKKIGNFDILKNKKNLKFPLQKEKIALSLEQFCFRVKMVEPVFIETFLKPIWNPKIFKIDNLLNKIGLDRTLTIEIGKQYTDEKNWTQKLMSFNEFLMKYMLPNENLKMEFKENSIFGNLQDSRTGYLAQYDLFEQIPALKEDFNIPDYCYCNDVSDQEEDDVLLNAWIGPEGTVSPLHTDPYHNIFTQVIGFKYIRLYHPNQSHLLYPFDSNSMLKNTSQVDILHPDLLSFPLFNKAKYVELTIGPGDMLYIPKGYWHFVKSLTPSFSISFWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZK0</accession>
    <name>A0AAD5TZK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zn finger-containing GTPase- Activating Protein for ARF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GCS1</name>
        <name evidence="8" type="ORF">HK099_004962</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000369">
        <property type="protein sequence ID" value="KAJ3218674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZK0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030100">
        <property type="term" value="P:regulation of endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08830">
        <property type="entry name" value="ArfGap_ArfGap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000014">
        <property type="entry name" value="ADP-ribosylation factor GTPase-activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="4"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="159"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="327"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="329"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="355"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3218674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="488" mass="55190" checksum="079FF7A0BD851A3F" modified="2024-05-29" version="1">MEYKQILSELQKNEAKGNKTCIDCGAFYPQWASVSHGIMFCLECSGVHRSLGVHLSFVRSLTMDKWTEDQIKRMQFGGNKKALEFFKLHPDWRENMTIQEKYTSKFARLYKEKLTADCEGKAWVMPAYERANSPMNQSRLSESQNSFNENFNKNLQNSNMAKNANNRNYGSTNIDNEWNNNLAKPGATDKERNEEYFRKKGLENNYKSDALPPSQGGKYVGFDTPTQNSQSDPLSDPLATLSKGWSFFSTNALSALDYSTKIAMTSAELVGQKLTETVIEPTTKAVRDPEFKSNMSSYVTHGLTKVTSLTSQIVKEGSNIVNSAIGHTPSGTGFNGQGNQKETNDWNGRDDWNNAAVSEQANYQSTGNNNITSNDWTASNRNVSDKNYRNTNNWKESGNTNNDWNNTSNEENITNREENLTSNFDEWTQPKDSTKKAEALDNWDDWPEAVSNTDTSKNDKKEVNASLNNRSKKVETKVDSWNDGWDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZU0</accession>
    <name>A0AAD5TZU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease H2 subunit A</fullName>
            <ecNumber evidence="5">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RNASEH2A_2</name>
        <name evidence="13" type="ORF">HK099_004900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase HII family. Eukaryotic subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000361">
        <property type="protein sequence ID" value="KAJ3218876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZU0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.460:FF:000001">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.460">
        <property type="entry name" value="Ribonuclease hii. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023160">
        <property type="entry name" value="RNase_HII_hlx-loop-hlx_cap_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF7">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51975">
        <property type="entry name" value="RNASE_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-2" evidence="12">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3218876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="128" mass="14990" checksum="79E388F083C9471D" modified="2024-05-29" version="1" fragment="single">DKILENFKFIEEGLDLKLGKDFGSGYPSDPNTVLWLKNNLDYIFGYPRLIRFSWSTCEKILEEKAAGCKWLDDEKENHGVDIRKFLKGKKKHRMEDDEAIINDMEDLNGPKRETWIRDLIGLKIVESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0I5</accession>
    <name>A0AAD5U0I5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ras guanine nucleotide exchange factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007016</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000648">
        <property type="protein sequence ID" value="KAJ3214118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019804">
        <property type="entry name" value="Ras_G-nucl-exch_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00720">
        <property type="entry name" value="RASGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1 3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="182"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="251"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="283"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="923"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3214118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1372" mass="154797" checksum="3BBBEEB014DF84A3" modified="2024-05-29" version="1">MDRFGNTALHFAASQGDYPLSYMLLLKGADPNALNKSSISPTTIACRCGHVILLKVLIKHGGVLLSSDEQHAKKIEALELKKKLTKESSKKNLTTNLTSATNTTNTATQNFKTSTFFCQEEGSTGLGVENREKKPSFFEPPLDLQKFFPKKKFHLASAAYLGIAQPLIENLNAMNMNICDENKCSVLMKAAFKGHLEIVQHLLTLGVDVNAKDNQGNTALVWACASKQLETVKCLVEEGNASVNGDNVTNNAPTPLITATFSGSYEVVEYLINKGADPMKMVGGKSPLMIAAWMFHFDIVTLLIDNGTRATFESKEWVKAGVILLRKIALEHNAWTTTYEGGNNSIISKNAPLSTLLAGTPPSPFTPLLAPPSQGISLKEKMSFLTAEEHEKLTKIEILFASPNFNDGQEIKKFIKENFILKKVKLSKTDESVNDLKTKELRKKSVNEEKFFDKMIEISLNSQMDINFSDRGSELDFSCLIVYQCAVQLAIAANKNIKHQYVVISAKAIHYASELIRAIENMENMVMSSPNNLRNFLNKYNEGIVFPNSALQLSVKEKTKLINTETSKQLMLCTRIAVGVWPPPNAITDMINAAYTLAHACKELADLTNLLGFFPLLEKKLDAHIEPFEEELIEVKVTNPSGQMTNISGLNFQEYNKENHLLQMREMSRRYEDGSTNELERSLSTRDLFKEEVEPHQEFIASLDLLLSRLIASVAEVKRAHTSHLKDEFISATAGVASCAESVLAQVQGYEPFLEASDNQLLFEVEDLKQIEESNININLEIQEEMLPTPYKSILAPLYQQITNASKLTLFRGKLAAQELAPLNASLEMIQATIPCLLSVKKLLVFVKQGAGKWQISTSEEKKKRELWRKECLQNERVKNMFQMWENASNVVKKIEFIAPEESAQLQDSKDGLVLIDSSTSPSKYLVKGGEIFKLVSWMTDHSFVDIEFTTIFLMTHHSFMTSLELLDCLIKRYAITPPYGLTKRMFEIYVQEKIVPVRMRVCNVLKIWIEFYFEGDFAQNESLVLYFRDFVENKISLDFQAMTKTLLKTLDFKIGIASKSKSVPPGITNSLHQNNSKPDFILMATDAAVINRLNLDPNNFYEWTEPLEMAKQLTLIDYEQFLRVKSFEMLDQIWGDKRMRELNSSSSGGKIKINHDTMLTGISRMIKQTNHLTWWVTNKVVNNATLKGRITALKYFAQTALVIIKINNYCREMKNFNALTGIVAGLSTAPIFRMKKTWAAFADKFPKTSEAYREVAELVSPSGQYSNYRKTLKEQTPPTIPFLGVYLTDLTMIDIGNSGYLPDSHYINFDKLRKVYAVIKEIQYYQHVSYSLQAIPTIQMVLQQLGTIVEEGPNVMYNQVLIGEDELYDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1J7</accession>
    <name>A0AAD5U1J7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000230">
        <property type="protein sequence ID" value="KAJ3221441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1J7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="575"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="16"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="4">
        <location>
            <begin position="212"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="788"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="790"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="811" mass="89379" checksum="FAA3D10C20D3E74C" modified="2024-05-29" version="1">MVLYFQIDKISTSQYNDVTFVVGAQKKEIKGLKGLLASQSKVFEKLLFTNSSTSCSNYIELPKMLEAPFETLIRFFNSGIIDEKLFKQNQKFCVQCSCVARYYEAWLLLKTSNEFFIKNLSNENFVESLLLTKEYQFEDLRKIVLKFSAGALSSVALITSPFDIVQEVFYSVKDCAFGQAMFFSLLLWVSNNSYTPNQLTALLSLINFEDFTSSELMQLEKLGSVGSECLSNVCKERVLKGAPVVSQQYAYNLNWEDTSETIVYSANEDEHTILSHQSVSSGVLTWEIDIIEVCGYFGIGISNALDTIRKTWAGDYNFGYLYCSKGKLHNNGKSVAGKMPTFKNGDTLRFELNLNMHQLRIMKMNYENEEYIVAFSELPKASYSPAVSLKTPGSATIRFISHLLPLENTFENHNELSISNLQSLILDVSAAAPHRRTATKTWHQSGAVFLFLLLSFATAQIPCVDIPGVTTCFQLPTFPPASTDVLSTTVISTSELPPTTSLPPTTTSVAPPPTSPPPVISTSEVVETSTSQPPTTSQASTSLKSTPTVGTTSSKTPTATADSIQNTSVISPNTLRIIIIVAAIVGFVLLCAIGVCIYNSCKRGKEEDSIPTYAKPSNYVYATKPLDDTTPLQTIPVTVSGASGYGLQNSNTASAPSMKSQSPPVDSYGYNSNYPAQGPTYNTQNIGNNANFDPYYNYSYQGYPDNGNGYAMANGGYDPNAVYDANGYDANYDPNYNQQYQNYDPNYDTNCNQLPYDGDVSQLQPQDYQQNNRDITSNIAADSTNFTKANENSINNPHNENSPPVNFQNAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1J9</accession>
    <name>A0AAD5U1J9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007187</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000677">
        <property type="protein sequence ID" value="KAJ3213770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1J9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="407"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3213770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="499" mass="56419" checksum="61AD0A84A898A6A5" modified="2024-05-29" version="1">MSLSIQIPSTNNDPGEESARLLQNSLNRSFLSPLAKSFTDSPSKQLENEFCKMFDCCNVKIQGLHELLAHYEQAHSSLKRPSSPTNVNVTHHQQSNASSFEDLCLKAFRAPQLLERKNFLVPMEDICKRAVVDLTDPDLTDIEDDLDLYSSDDNSADQTNPRRNGTGTSSSRSSSNDTVLPSSYSDPIVTGFADRITYKRRQNRNSTTKKRTRNEQQRSIQNAKVPKINIINIIDDIDESTDEVDIDILTVDDDDSTLINQVTQLSILPISPPTSENECDDVEDLKKVRKGDILLDEKDDDNDHGSVTSQDDLQEILQDSTTNLLDTYQNSQGQQNQKVPRQSSLSILDPETGERKYICAVTTCKKQYKNANGLKYHLSHAHPNGEGVPQEYLLFQKKKEEEGYRPYKCTVDGCQKRYKNLNGLKYHIEHTHVHLLPPSHHSSSFSSSFAMPPNGINYNNQMQQQAGRQQVNLHHHAFPQQIPMGYPSLFPMYPVVNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2D4</accession>
    <name>A0AAD5U2D4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ras GEF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_004907</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000361">
        <property type="protein sequence ID" value="KAJ3218883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2D4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11883">
        <property type="entry name" value="SH3_Sdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056685">
        <property type="entry name" value="DUF7783"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25006">
        <property type="entry name" value="DUF7783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="2"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="9">
        <location>
            <begin position="662"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="7">
        <location>
            <begin position="829"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="593"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3218883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1080" mass="121305" checksum="F3AA1CA8C3338D36" modified="2024-05-29" version="1">MTKRFIVSALYDYVGNEERSLSFKRGDIIRVITQLESGWWDGVCKGQRGWFPSNYVTSTEIATDIKISSVELHSNSNSSATLISAVESNVSNNLISPFSDRSYQQYQKQLNEGTPTDTLDDISAVHQSSLTKDSLKSSSLDKYSLSMSSPSQTITPMSAISEQSFGMYSMKSPSSAAILKFDQNLPPNWAKKQNSDGKIYYQNLLTEHISWSLDNVHMENGELMKSNSSQPNQTSQNIERDEDVVSNKWNWNALSDDIVNAVHNLNLSAKSSRKENFVSQSLQIMESIKIMLYASGTFQKDTPLVSSHKILKTNHKHIMNALTKLGLSAKLASNTPCPVDAVQHMQQACHDVLLAVRHFVSAALEAEISINNLDGVDLSEVTNWQSDMSSYTSLMETNQDVSSFVELQQKQADADLIALYEKHTKSVVKTISLLVRLIRSNQCSSSSLIAEVRSVVTDVGNFLALVDEIPVDTLSHEVTVDFKVTRLALYNSISGLVMATQTATSPLSPSNALEQVVLSTGLVEKAVKDLFASTKFMIEEKEEVDQLSDIKKEEAALIKPRRTVSLSSAIPPVITPMAEGELNNNTNKDLKLGHGQPQSAGPLTTPNGIFGDGETSSPVRSKIKKFFGEVPDSPISVGVVKQETVPPFLQYDYGPNDIIFNMEGKIKGGTLEGLIERLTPHDSNDSNYTTTFLLTYRSFTTSTEFFELLKKRYLITPDPFLSKDELQQWVEKKQTPIRMRVFNILKSWIENYSESTPEDLKVLSEMKDFATVMSHSIQFASQQLVKLVEKRILSLETNTPSKKIIKTSNICPLPILPKNLKKIKFLDIDPLEIARQLTILESKTFNKIQPMEFLKKAWSEKESDNSKNVKEVAKMSNLITSWVAETILLQSDLKQRAAHIKHFILIAEKCRTLNNFNTLMSIMAGLNSAPIHRLKRTFELLSSKTQTSLDQLQSLMSTTKNYSVYREALHASYPPSMPFLGLYLTDLTFIEDGNPDLLKPDNRLINFSKRSKTAEVIMEIQQYQRTHYNLTPVVEIQNFIINCLTESLDENKIYDLSLQLEPREREDEKIARLLSESGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U355</accession>
    <name>A0AAD5U355_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004851</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000357">
        <property type="protein sequence ID" value="KAJ3218987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U355"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="115" mass="13709" checksum="4443D9893484F03C" modified="2024-05-29" version="1">MVRTDGVSICVLLSSPKPKQKESLPRVKKRKIPEKSEYFQDNLEDLHFNKVYIDPNKRDLLYCLGESGLKHYRKIRERYEVATEEVVNYELTKKTLDKTKWNDHMEDFLLSFTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3C6</accession>
    <name>A0AAD5U3C6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Xanthine dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HK099_001575</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000146">
        <property type="protein sequence ID" value="KAJ3223048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3C6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000015">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.50:FF:000001">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="CO dehydrogenase flavoprotein C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="CO dehydrogenase molybdoprotein N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="Molybdenum cofactor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="13">
        <location>
            <begin position="9"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="14">
        <location>
            <begin position="241"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3223048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="924" mass="103335" checksum="CB2529BA975E4825" modified="2024-05-29" version="1">MLASIPVRALLEFYLNDKKVFVKNPDPTESLISYLRRSGLTGTKLGCSEGGCGSCTVVVSHYDYLDKKINHLTVNACLAPLVSMNGKHVITVEGLGNTQNPHPVQEKIANFHGSQCGFCTPGIVMSLYALLRNNPSATDHDIEESFDGNLCRCTGYRPILDGAKKFLVNKKPCKASCSEEGYCKSKNATERCSHSSGDGDDIEDIKVHPDLEEREIVLEFPKVLLNEYENGRLATPDAFYFDGGKTKWFQPSNLDQMLDIMHQFPNAKVINGNTEVGIEVRFKSLEYPILILPSNINELKTFKMEENGVSFGGCMTIAKFQKNLLDICDIKKSNLKRHQIRGFEALLENIRWFAGNQIRNVAAIAGNIVTASPISDLNPIFVAMGAVLTVQSKENGLRKISMEEFFIGYRKTALLPSEIVISIFVPYTREFEYIKAYKQAKRKDDDIAIVNASLRFNLERETEGYFIETASFAYGGMAPMTIRYRYINDLADFKFFRPMSAIKSVTGRFWSPEVIPSIQEALLADMPMSATTPGGQVEFRKTLAYSFMEKFGLYISHEISQLDKSCSINRPLNERLLSSLKDIERDISKGSQSFEQHSGSDVVGKSTVHLSALKQVTGEAVYTDDIPKLHNELYAIVVGSTEAHANIISVDYSEALEVEGVVDYISWKDIPNFDIKMDLNDKHNPNIIGPVFKDEELFATKTVHFVGQMIGMIIAHDERTARYASKKVKVTYEKLPTIFTIEEAIDKKSFFPYPRELANGNFSSMKSAKKNDDRPLSLATKFVSGKIRMSAQEHFYLETNVSLVVPKKEDGEIEVFASSQHPSECQHLVAHVLGVLSNKVTVRVKRMGGGFGGKETRAAFLTCGMAVAARKHGVPVRCMLSREDDMVMSGYRHPFLGDYKCGFTEEGKLISLECDVKNIFLFIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3W4</accession>
    <name>A0AAD5U3W4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_003897</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000262">
        <property type="protein sequence ID" value="KAJ3220938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3W4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="7">
        <location>
            <begin position="560"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3220938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="851" mass="97220" checksum="29D92F73AA931AB8" modified="2024-05-29" version="1">MFADEDNTYDHPSIDDNNDLLDELVTSKDKSISDIYNISLKTGDWKHESKLPLFIDHALPTRAMYVDYFNEPRRTIRYGKETIEPECRLSYDVLGVCSIPRLYRPLVSLPIIINNSIHTMIYSDIDGIDGISESIKYLSNSGTSWYFSNTRLMQIDRNNVVMNRVISCYRFQPLHIFSDIAIHEIAQHPTGIEIWRRLFDNIEDFTRRPGIFGIIHDNSIIDIRPYDHDSEIINDSRNIEARLTQDHWSGFIDCTYTPMSLEAGRIRSVVHGCKYRVMTSITIKMAKSILNLVRSGIKFNTASNKNITAEDWIFYCCGKACIITAECAMDIVELWRSFRSHNAPSIHAFNSIRIMVMTVSSGCIMKPINAKYGLNDYNVWDNAMWVDSIVYNTPGMLEFMTGYKRLDTNNPFDNVKMGIHLIPFFLDDEPPRPALATSMSMQAICRPRVELTSTIAAKHEFLPVVRTPLMQSLIEAMPNRQYISIPGVPLLVVFANMKGNYEDSVIINKSINDLGLFAHASLVHHPVPDRVPVLKAGYKLTEKDKWFRPHANATVVKEGLSRSKARYVTVRMESSVIDIGDKLGTWHGQKFTVSSILSDDEMPTFICCRTNERIIPHIIVAATSVHNRGTLGQIYESWIGMQTVDNIRFDPSKNDKYVIIDSFDEQLPSMQQYSCYINNNDDNIMESFTNDDCKYVKADYGISHFWLLSHLARDKQHYMNEYPMSATPKKGKLRGSSVRFGEMETLSMMSGGLINSLSYLSDTSDLVNVTVCVKCRRLSLLCDCPTSHIDETNILVRNPLVRFDIFRSIYSANGITQIDDDSEIVRDESSIQLEGKHKSDPFIAESFKYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3Y4</accession>
    <name>A0AAD5U3Y4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Centromeric DNA-binding histone H3-like protein cse4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CSE4</name>
        <name evidence="14" type="ORF">HK099_003037</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000205">
        <property type="protein sequence ID" value="KAJ3221853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3Y4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000096">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810">
        <property type="entry name" value="HISTONE H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="13">
        <location>
            <begin position="37"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3221853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="145" mass="16993" checksum="40B303AB4513BFB5" modified="2024-05-29" version="1">MARSTPVKQSRRRPLQSIGRKKVTVSPKKSKPHRYRPGTVSLREIRKYQKSTDLLLRKLPFARLIKEIASDLVQDQFSQEGKRSERDQLVFRWQSQAILALQESCEAYLVHLFEDANLCAIHAKRVTIMQKDIRLARRIRGRDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U425</accession>
    <name>A0AAD5U425_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial splicing suppressor 51-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U425"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47570">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47570:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial splicing suppressor 51-like C-terminal" evidence="1">
        <location>
            <begin position="111"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="245" mass="28046" checksum="127F699EF917B1D8" modified="2024-05-29" version="1" fragment="single">YNKKERLYDYNTVILLVHHALHNIGLYRRICHCFSKVPYGILGLEMYSQCKSVENNLNEQAKFLGVPESLLPLDKPFENGVDTRKIDSWKSYYENRNIPLDSPLALILEYPLTIFHLLNKFVLPKGALPSKFVIHLVGVEKEADLIPLFQVLMPLFPKMNLFIHMIGPAIPSQLEEQHRIFSYENTTLKSKLTITLTSSAYDLTHLQGNNGMLKLVPEDCRKPDVIMGLNSGLMAGPSWYVIFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U488</accession>
    <name>A0AAD5U488_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000647</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000116">
        <property type="protein sequence ID" value="KAJ3223817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U488"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000060">
        <property type="entry name" value="Ubiquitin conjugating enzyme (UbcB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="16998" checksum="D10074B334A16163" modified="2024-05-29" version="1">MSSQRRIQKELVDFNKSPITGIEITPEENNLYKWKVTLTAPNNSLYKGAVFKVNVEFSTDFPFKPPKVVFGTKIYHPNVDDDGSICVGILKNEMWKPSTKITEVFYALLDLLENPNPDDPLQTSIAEQYRNDPATFSKNVKEYIKKYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4H8</accession>
    <name>A0AAD5U4H8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_002207</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000171">
        <property type="protein sequence ID" value="KAJ3222534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4H8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="23"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="12">
        <location>
            <begin position="388"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3222534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="800" mass="90655" checksum="B5E18FF0A1A73125" modified="2024-05-29" version="1">MSIEQYGKNFPILLRTPSPRGKVELLETIGKGNYGYVYRGRLVATKETTAVKVVFLKEDELKETLLEMDILRQCNHPGITRYMGCFLKGLDLWICMEYCGGGALDTLYRTLRKNLNEDQIASILYDTVSALDYLHREVFLIHRDIKAGNVFITENGDFGVSAKLKSSNGRARTFIGTPYWMAPEVIMTDPESSSSKTATYDTKADIWSIGITAIEIAEKNPPLNDIHPMRALFLIPTSNLGLAKPKNWSKPFQDLIAECLIKDPNTRPTAIQILNHPFFAKAKNLDRRRIIFELVQKVRVIREKKKAGLDIDDEEDEKKEEIPQKVLSETMKLAKKAQNASNKDVSSNSKDQLVDVSIVIDNTFKSFQETQPAVKSVLLWKPITSVLKLEVQTGDTLDNRYTLIGTTTGLYFIDMERDTGAGEMIPLIRNIRFKQIEVVQEYGVLMALSGKHDHIRQYKLESLRKLIKYLTGTPVSAIMHPDGSQDKAEDEDLYKHLKRDVEDEAVLISKWTSDYIKILGTKNTQYFNIQKTETSIYMGALFRQDLLLFQWAKEPYLKFMKLKAFWLPETPKKLKLLHDGLSIKEICLMYNNESNLINLDDSKVKEVKVHKEFSTNSNSKNPKWETFSQIPFSDSKLKELRELSEKSGTINKKLLAVGGNTPKTNQVVGDRYFLATYDCHTRVTDIDAQPMIGSGVGGWKSGVTWQEPPIDLILRPIDFVIAIGKQSCQVVDWKSASLVQEFTLDKEGIAKLICDKRGGILCSVERKKRGTVVFKVYEPNVSLNKGGAKVINSSDDITKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4J3</accession>
    <name>A0AAD5U4J3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tartrate-resistant acid phosphatase type 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ACP5</name>
        <name evidence="6" type="ORF">HK099_002269</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000174">
        <property type="protein sequence ID" value="KAJ3222464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4J3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051558">
        <property type="entry name" value="Metallophosphoesterase_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161:SF14">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041948880" evidence="4">
        <location>
            <begin position="24"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="361"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="42"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="397" mass="45273" checksum="73F1FAF07B2A223E" modified="2024-05-29" version="1">MIASKLTSLLIILQLLSIFKTLPLNTTLFQETTISSFQTFEFLAIGDWGSGSADQKMVASAMKFFSDRNNNSNPQFVVGLGDNFYESGVTDVDDSKFKTVWTDVYNGSLMQLPWYLVNGNHDWRGNTDAQIKYTSISNNWNLPDYFYDLEVYVGNGLTAAFIFIETNLIFGGIKYEGEPSMRKLGWGEADYAQTQLNWIEDRLRKHYTKDYIILVGHHPVNICLNGMGNATTINKLVDLQRKYRISAYINGHTHNLAYSVIQNIAYVITGSGGKADPEKLRCMEGDFSKGGFGFVRGLIDQTGLHFEYRNENNTLLYTSAPVKKRAHLVPLHLLDKIYHIIDDFNSKKNINFFGSNRHREFIYLFVLGTTLILSPFLFFVGVFSIRFVVKKCFKKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4S1</accession>
    <name>A0AAD5U4S1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000090">
        <property type="protein sequence ID" value="KAJ3224534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4S1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="331" mass="38531" checksum="53B90666E55946EE" modified="2024-05-29" version="1">MDFNSKDVEQGYDNLDYLYSRCSICFDETHDFCLTRCRDQFCKGCFQRYVREIVKSSWGLAIKEITCPVCNDALVGQEWKRYLDEKTIELYELYNQPHRAMSRYCGDCFIEIRIAQKPIKSSEERQFRFSEIYRLICNLFNEYKSKNKDSNCLARFQADFCNEFSGGGNGTKSILDIYTNIMIDVGKLVGVRCSDNGAFKEGAVLTLNPDLLQKVTLISTMFIPLETDEAKWKKLQFLHISNFPKVIGETPFHENLACTKYMKNIIARNEDTEKVANFKWKLENRCELDRTRSKIQLAEEKELLSTSPSKTKAFTELGVPNVFQIEEKFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U522</accession>
    <name>A0AAD5U522_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004469</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000316">
        <property type="protein sequence ID" value="KAJ3220058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U522"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="136"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3220058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="30839" checksum="FA466D0A27FDDB88" modified="2024-05-29" version="1">MEHNNSFSLKRKYQKDYCKFFAIGECKKLEECEFSHDFDNSLSQSFDNYYNSAKEQKIKTKKCRFFEKGICRSGESCPFIHQLNSHWKNEVTNSSYEESLFFEQLKRSIDNTIEDKIVDTPSSTDGEHKEQKCIHNTDIEKELNKLRKLNEIEKSEEELFFFEDNINEKLLVALNEKIESERASMTKRFSEVNKKLDDCQHENKNLLEIVSQQTDLINRCKLPNFYNENNGDFRFSLLEELQIPFSILSEKINNLEKNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5C5</accession>
    <name>A0AAD5U5C5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000075">
        <property type="protein sequence ID" value="KAJ3224970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5C5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="95" mass="10927" checksum="9A2FF29BC2BA7E89" modified="2024-05-29" version="1">MPTPTQPCKYFPFGACTNVRCVYIHEPTLYPQPEDISGLSLLMKLHQQSLKQPGGPDLNLVPQYKGVTYQEFEIGFRNKMTCKQIVEWKIAHTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5J9</accession>
    <name>A0AAD5U5J9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-ketoacyl-CoA thiolase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ACAA2</name>
        <name evidence="8" type="ORF">HK099_007434</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000072">
        <property type="protein sequence ID" value="KAJ3225059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5J9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000010">
        <property type="entry name" value="Acetyl-CoA acetyltransferase (Thiolase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF107">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="6">
        <location>
            <begin position="9"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="7">
        <location>
            <begin position="278"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="4">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3225059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="399" mass="42113" checksum="01A147BA22B6F28C" modified="2024-05-29" version="1">MSKKLAKDIFIVAAKRTAFGSFGGKLAHLTANELGGIASLAAVKQLPEGTPVEGVIYGNVCQTSSDAAYLARHVGHRAGLPITTPALTVNRLCGSGFQSLINGAQEILLGEHETVLTGGTESMSQAPYALRNARFGTRYGVDQKLEDTLAHSLTDQFPKKTPMGITAENLAAKYKIGRSEVDAYALQSQQRWAVAQEAFRFKEEITPIHIKGKKGTEVFEVDECPRPQTTLETLAKLKPVFIKDTGVVTAGNASAITDGAASIIVSSASAVKSHNIIPLARIVSWFYCGVEPEIMGIGPVPAIKGALKRAGLTLKDMSLVEVNEAFGVQYLAVEKELGLDRSITNTNGGAIALGHPLGASGTRIMAHLTHELHRTGGKYAVGAACIGGGQGIAVVIERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5W8</accession>
    <name>A0AAD5U5W8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000170">
        <property type="protein sequence ID" value="KAJ3222549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5W8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 oligomerization" evidence="5">
        <location>
            <begin position="52"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="4">
        <location>
            <begin position="120"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3222549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="20595" checksum="FF82EB76807FF538" modified="2024-05-29" version="1">MNYIFRSSLTRSVSKLNFFKTSSTHGSKRDFTIKSFTLQEATELSEKVPKNIQSLVDQISKLTLLENATLVKELKLKLNIKDIAMPAMMAAPAAAPAAGTTAAAAEPAVEEEKAAEKTTFSIKLEKYEAAAKSKLIREIKILIPGFTILEAKKFLESVPKVIKKDVPKEEAEKIKKLLDSLGGAVTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Y2</accession>
    <name>A0AAD5U5Y2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Y2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="207" mass="23888" checksum="527818FCC6BCC414" modified="2024-05-29" version="1">MAEWILADNFNKDNVGLDDKPIPGTKRHNILYLYPNEEYKQLYITVPKAEESFVKIGKPQQREVTKKDGTKFTPPRKSSTIFLDKNNISHMNVYNVIKDITEVVNSNTKLSSTFAYAEHPDNICIFCTLIEDRKNKVYTSFYDQEKVIDVEKLQTFIGRPSLSFSVNMETGKIYVQITAAYVHREIRRIFRGHSQEISPGNISRGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6G4</accession>
    <name>A0AAD5U6G4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000084">
        <property type="protein sequence ID" value="KAJ3224706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6G4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="90"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="260" mass="30624" checksum="3EC4A9E57321720B" modified="2024-05-29" version="1">MQEYATDFLSLVLLLETSSAAGFFVYKGLEKYKPAYLKTLKKKISFSHDNKQNDSIKNFEIESHNSLIEEILQNYCNKKKLDQDYWRYKHHVYRVYNLAIMQASEFGPVSKIEKEKLAVSAAFHDMGFWSKNTNIFDICDFSIELARSWLVKHGRNKVFEETIISIIKSHHHSKKKLNEDSKDILLIKWFKTAHEIDLSCGLKTFGYNQADINRCRQSFPELSFFRVLIFRSFEKVLRMPFDLLKLIPKFIMKNLAIKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6J1</accession>
    <name>A0AAD5U6J1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005499</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000043">
        <property type="protein sequence ID" value="KAJ3226146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6J1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207:SF32">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="RIBONUCLEASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNase III" evidence="4">
        <location>
            <begin position="42"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="3">
        <location>
            <begin position="197"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="290" mass="32676" checksum="6C94B83249A62145" modified="2024-05-29" version="1">MSKVNKFKLIKHIPILKYSTCLKNNEINSLSQNLNASQVTKVSNFAIKAGLLLKNPVTLMNALTESSFKIDSTTQHERLRNLGKIVLNFYTTEFLFFKYPNLTADVIDTFRKSYVGVEALTEIGTKLNVPQVMTLKDPHNPYNKGPPEKDIVSKVTLAIIGAIYQEKGALEARNFITNHFFSRKVNKVDQLNHVIENPLHLILKIAEKLKVKPVTKLLKETEKPNGEVSFVVALFMGESKVSEGFGNTLKKAEARAAKKALEDLYLEKIKSVELSESFLKQEVSLLQLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6M7</accession>
    <name>A0AAD5U6M7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 20</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Mediator complex subunit 20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MED20</name>
        <name evidence="5" type="ORF">HK099_007539</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the Mediator complex subunit 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000074">
        <property type="protein sequence ID" value="KAJ3224991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6M7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013921">
        <property type="entry name" value="Mediator_Med20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08612">
        <property type="entry name" value="Med20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="161" mass="18722" checksum="D5F0FE5900A3A1D0" modified="2024-05-29" version="1">MYTFYRDNEKVLLLFQTESRTFAYIDDNFIHATSVLNSIVKKMKNIWTLRNTIKIEGYEYSTNYCSQTIILRISNILVGNNINGILLQSYILNENSTLKTPINLKENIALVVSFLNSIFGDIFSVKEKEYSYENAGIESNTFEEQHLVFQILRTLIDARIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6X3</accession>
    <name>A0AAD5U6X3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000029">
        <property type="protein sequence ID" value="KAJ3226754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6X3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="79" mass="9162" checksum="9BCEF7AB6C2FF693" modified="2024-05-29" version="1">MFFLNEEEKFNKSLTDSQPKVEKFRLRDCMPDSRIYFGFLVSGLFTYLGEDIFGVASAKQILFHIGFGLLFFIFMAGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U795</accession>
    <name>A0AAD5U795_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ZZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_003620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000024">
        <property type="protein sequence ID" value="KAJ3226997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U795"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930">
        <property type="entry name" value="OVARIAN CARCINOMA ANTIGEN CA125-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930:SF0">
        <property type="entry name" value="PROTEIN ILRUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PB1" evidence="8">
        <location>
            <begin position="4"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="7">
        <location>
            <begin position="282"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="6">
        <location>
            <begin position="340"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="111"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3226997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="43456" checksum="CC8DB7E7C59B73CB" modified="2024-05-29" version="1">MSSKVAIKISFNNSLRQLHVDETTNWVQFSSKVRQVYQIEKIFPLIVTYMDEEGDIISVDTEFEFSDLIKQALVEKRTLRLEVQLQPAVENTEKSSDDGFVKISHVQRQDYDVMTSDPAEETVPSTSSLPSNLLTSKESQQPEAVAASLEGASSESNKTSTSHNEKGKSKVEEPKNPFETLLESFVPMFECVNNHLQDKNFIESLQEILKNNESQHEQLFEKILKNGSHLPFAAFFSDSYKDSCGSHPFQFGKCFTVGESSCNGYNNKENLGKNTNGVKLPWFGVTCDHCNKSNFTGVRFKCKICDDYDLCSDCHGKDKKVHEDHDFKALENFEQYRNYILVEKNLRVLNELGFFDEALNIDLLKRYNGNVNRVVDILFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7A6</accession>
    <name>A0AAD5U7A6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Endoplasmic reticulum retention protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ERD2_1</name>
        <name evidence="12" type="ORF">HK099_003515</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7A6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046923">
        <property type="term" value="F:ER retention sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000133">
        <property type="entry name" value="ER_ret_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10585">
        <property type="entry name" value="ER LUMEN PROTEIN RETAINING RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00810">
        <property type="entry name" value="ER_lumen_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3227062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="183" mass="21262" checksum="08291D8EEFF53AFB" modified="2024-05-29" version="1">MWSFSVILESVAIIPQMSLLVAKKKLIQLETDAIKDENILIVKYIAALGIYKGLYVINWLFRYFFQGRISWIQFFGGILQVLVVIAFLGRYYRRIKKEYYHIIEENFSDENPNDETLFNLQDEGRYLERNSFVISEEDLPNYQGQGKVDGGENVKFANTVKEEIPEQFLSAGDGLDKIENDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7A7</accession>
    <name>A0AAD5U7A7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_006595</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7A7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="517"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="612"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="673"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="707"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="736"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="28"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="224"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="465"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="843"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="862"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="884"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="929"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3225561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1179" mass="135183" checksum="CC2883BBA5B7196D" modified="2024-05-29" version="1">MFNDTTGVPDKEKIEKTISAGIIYPSFTFLSIGFVCFLIFCFARPRFRDIYSPRRGLNRCKPPRIQNGFLTWIPVVFNTPESFLISTVGLDGVMFLRFFKMGIQQFFLLSIIGLTFLAPINYYGQPDRADQSNFDDLSVKYSEEASSGGLFGFLNNFNEVEFLTKLTLENVPASLLRVHIFYLWTVSFIAYTFLIVYYRDYVYLKFQYQEHVLRKSRLSKIDMRTVMVYGIPTELRHEADLAKFYEGLGLGRVESVVICRKWSRLREAVEKRSFYLRHLERCYSKVLKLAANKRVQSSVFLFHRRRTSSQERDGSSGFDIYDRNHSNSSNEVFGYSDFSESCCVNEITSRLDSVDPKYRPKHRTGFLGIFGPLVDSTDYYARHFLTYDRMVDQLRKNPVSTNEISKATSVGFVTFESPESATIAAQVNVASHPFALMTRSAPEPRDIYWQNLSSKTAESYIKFLRSILVSSILFFLIFFNTAVTSSISLLFQIDVILKWIPPLRPAFDGLSEGVKQFIQSVIPVSAISIWTSTLPSILLILSEMQGFEARSWIEMSLLSKYFFFLFWNIFFVVVTSTTAIKGKFSDVESPDKIIKLLGNSLPRSSTYFVNYAMLQAFASFPAQLLLLGPLFLTWVYRIIPWIKGTTTPREISEAYYPSILTTINYGISYPIPILIWVIGMLYAPIAPYMLLYVHIPQYETGGMHFPMAVKRCLGGMIIMQLTFMGVLSIKADSLEYISFILSVLPLLLITITMFWWFKNGYEKQIQHLPLDILGKVGRDLETQVKTTDSNGVSCKNEWSKTDDKELGIVAPEVNLIPPGDEDHNNIKKLGELKRKLSSRTLDRTQTYRSAVKRKSEQDLKSNENFGSLQSNAKENNLFGDDALYSSSSVPQTNPNTFNTTSVNNRFRSSTENSSISMFDEPNPWEASNEKQNIPSEEQPLLSNNNRYIYDHNNIYSERISEENVEDGDYFNNSMNNRSVRRGLLSSFEENEETNGNIVSMHLEPPMQRCPGILDPPLESSIPVIPDMDEEDFMNAISGEGQQYPSSEGYSTIARKINQNEIDLILYTYLHPALIGRLPISWLATDNDNFGLKTKEQPTSLMEAREEQKFRQSELRRRVIAKQKFYCQQHNFNDDGERSGNDIDIDDDVELQPRERNVSFKNRITSVIDALSSWAHLQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7N6</accession>
    <name>A0AAD5U7N6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000012">
        <property type="protein sequence ID" value="KAJ3227677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7N6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="36243" checksum="74BA7E44F57B9DA1" modified="2024-05-29" version="1">MEEIDSFKSYLDDLVKMFLKDKPVKPPTFRNHCSPKKTNYQIWKESEESKLLYANMDNPYSEKKIELPESVEVNLENVHQKLVLPDLKKKMDVLLGVAEFNSRFGEIDERSKLLGIGSSSATIDIESNVTSDGKKILNECNIIADLTNLALHKMMQRGETLYDIKVRADNLKGAGNLFKKKTANVERDTYVQSLKVIFKFILGWDRSCIGAAPGTVWGCPITCTPGTLGCPLGMPPVMPGVPGAPGGAPMVPGAPSGAPTIPGAPPGAPMIPGAPPGAPATPKPPSVYITYSSLNYVKGYLKNLCIKIKMFNFREKARKTQTWINYNKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7X6</accession>
    <name>A0AAD5U7X6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000090">
        <property type="protein sequence ID" value="KAJ3224541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7X6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041984655" evidence="1">
        <location>
            <begin position="23"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="174" mass="18559" checksum="77BEE051E2371F9D" modified="2024-05-29" version="1">MNFLFLCLMYFNILLYTNYCFSLNIMDKKNFFEAIIIYNNNVDIRAAMVTKEVIVIFADPAVAGAAGTADVDAEAAADALALFLLSFVIDGNVVFNAAFPSGALVADPPPAAPPPPPLLLEPPVEAACSLHSVDKVCKFLVSASQVCCLKQVLKKLATEPSQGFEMAPGKVVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U827</accession>
    <name>A0AAD5U827_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051240">
        <property type="entry name" value="Mito_RNA-Proc/Resp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933:SF11">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="198"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="336"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="888"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="1061"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="1096"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="1234"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="1269"/>
            <end position="1303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1544" mass="179391" checksum="433BEE6764C4653A" modified="2024-05-29" version="1">MYFPHKSLKFSSENLPPTEGTSLKRFFSNVYTVVTINEKKLTEDKIPESDLSTKTVSLLEDSNLSDSKLMFMMQSGYSTIKEVISYFNYKSAQNKVSPSITGYYLAFLAANECEENLSTLLNSIKYPSISHYLPLINHYTISLNRRKVTYYFGCLLTAKIKPSIYIYNRMMNCYLEHSQSSMVIKLFNDSQFNDVRPNSETFNVIIAACFKEKRFGKLEYFCRYMINNKFQPAAYAYDASIKYCAEVRDYHQIDFYLKDMMAKNISRDLSFSTLINYFSVNNDIESVKDFLFGIMEHHIKPNKFHFNCLIQAFSTVNATESEFYFKEISRNGLQPDAASYNSLINALLISNQVLKAENYLKEMLSRNLFPNKANNAFILEYYYRNKFFYKLETYIKILISNNLILDMSWSVLLKVYLEKIDLYIDENFVAVNSITHTRNLQLQKLLVDAPDFKIVPNVAILNIWIKSHTDVNSAVKAFDMMESCNVQPDRITYLNLMGVFLLSSESNAKLFYQTSTEKGLNFTTDHYNTAFELILESDASITKVDRLFQYMRSRDVKFDEETIYLLSNIFMKHQDITLVKYCFDSITPNNLNKKILSCFLNFYVNFKIKDLVKFHLKDIILNTTNAPTGRKEDLLKSLSSKCEILAANVEEILLFGINYVQNRNIPNASFKDSLPKNVFQFIDNKDLLLDEVASNELEVNRIYFYLRSLIALGHIIRDEKILNKSLNNFVTDYSIAESELFEILNMTQISRVTFYELILRYFSWRFRPDRCSVYWRHLTAEKIKPNAIMYFYMQSSYKQSSRRVEQHFKAMLASGIKPISKNYEVLIKAEIKNKNLEKAEYYFDKMALMKLVPSIVSINFLITAHSVEGHIEKVQYYYQQAKKFNLLSKLNYNALLIAYAKVSNEDEILYFFNEMQSMSILPEHSTFNTILKVHSRNMPKFTQYLQNFYVTGFTPCNVTYHIVIGAFLGFNNLKKVGYYLKEVKTKGFKLNQKLLSSIVAAFTKVGDLQQVDEIVKYMVAGGIKLDHHIYCSLIKMYSILKNLKKVEDIILQMQKDSITFDVPVYNAIIEAYVLNNQRNCGERYYQKMIANDLKPDIKTFDILIKAFSKVKNEKKVLFYFEELEKEGIKPDAHLYGALISSSENNIWRVEFLLQEMQTQGIALNEFIYTALIRIYSKVNNRDKVEFFIRKINVDKIERSSFTNDAIFNYYSKQKDLLMVNETLDLIFNSKLNVDVTTFNNIIRGFANEKDVGKVEYYFHYMQKCGVAPDLFTYNILLSCYSKLADAKKVDVYFEKLVSSGIKPDIVTYNTLIASAIKDDVVKAFRYAEELLKEGLTPNIITYNILYFSSVGKFQNLDEAKELLISNMKEFFGLSISPDISTWTSIMTCFSYCNDNPTAVYIFRKLTGTFGGLDPPDLPVKIKELNLPNETASNIMFSVALDACKHGNLYEDLEFIWDFALDYTVNLDSNVLTSYIEALCHFKKFEKVIYILKASLEKYNTGKKQYYPLPNSKTYTSTLHGLKVNGGLKFIPTLRKIIFSNTDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8A5</accession>
    <name>A0AAD5U8A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tetratricopeptide repeat protein 30A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TTC30A</name>
        <name evidence="9" type="ORF">HK099_005879</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TTC30/dfy-1/fleer family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8A5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120170">
        <property type="term" value="F:intraciliary transport particle B binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000211">
        <property type="entry name" value="tetratricopeptide repeat protein 30B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039941">
        <property type="entry name" value="TT30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20931">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20931:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="548" mass="62921" checksum="9D543B8F2A04A0C9" modified="2024-05-29" version="1">MSTATPSALFQIPEGRYTHTIYSYIRDSKFTDVIKILSAELDSFPKSRAALSLLAYCHYQVQDYATAADRYEQLVQYFPDVAEYRLYYAQSLYKSGQYQPAQKGCQSIDNPEFGHKVLCLQAAIKYETNDLAGCKLLIDQSPQDDPETMINQGCLLYKEGKFAEACAKYGEALKITGYNAELSYNIALCHYQLKKFVPSLKYIADIIEKGIRDHPELSVGMATEGIDVRSVGNSQTLHETYLIEAFNLKAAIEYHLKNYEAAREALTDMPPRQEEELDHVTLSNSALMNMEEDPTTGFEKFNFLLQQSPCPPEVFSNLILLYIKFEYYDLAADLLADNQVLVNKSLSPEYLDATLLRQSSPEESYRKFDDMSNKHVETLRKLTKQVQEARQNHNDELVKQSVNEYDEAILDVTAIVLANLCVSYIMTSQNEEAEDLMRRIEKEEERVTYEDNTKRTYHLCIVNLLGTDTWYYAKRCFASLYETLTKHMILLKDSVFTDALQFFDNCELYGRDIPVLIDPVGMENIDPSKNSVSYEARRLKALFLKLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8E5</accession>
    <name>A0AAD5U8E5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003333</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8E5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="146" mass="16822" checksum="F7371D17900B25F7" modified="2024-05-29" version="1">MSENSHHHSTHMHSNHNIPEKLENSHDHSSDMSMVLNWSLNATIVFKSWTTSSEISLFVSCIIIFLIAYYQEYLKVFVFAEDVKLKNYIENKAVVNLSEVNVVDDREQQEVLLIGTSANNVRGFNKIIESPLFFEQLSNGYKDVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8S6</accession>
    <name>A0AAD5U8S6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005346</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAPRE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000041">
        <property type="protein sequence ID" value="KAJ3226241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8S6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035372">
        <property type="term" value="P:protein localization to microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000028">
        <property type="entry name" value="RP/EB family microtubule-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004953">
        <property type="entry name" value="EB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036133">
        <property type="entry name" value="EB1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027328">
        <property type="entry name" value="MAPRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10623">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03271">
        <property type="entry name" value="EB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140612">
        <property type="entry name" value="EB1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51230">
        <property type="entry name" value="EB1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="10">
        <location>
            <begin position="5"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="EB1 C-terminal" evidence="11">
        <location>
            <begin position="175"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3226241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="259" mass="29707" checksum="182A4E0EF4DC9724" modified="2024-05-29" version="1">MQGMGESRTDLLLWLNDLLQLGYTKIEQCGSGAAYCQIFDSIYRDVPMSKIKFNAKQEYEYVQNFKVLQGVFLKHKIDNAIPVERLLKCKMQDNLEFLQWVKKYWDMYYPGGTYEAVSRRKGEVGSAGSKPSMKKSTSVNSVSKAGAAATVARRVASPAVPKANPAPKKNLSPSLELEYQKQFDELSQNNLELKVAMEQMEKEREFYFSKLREIELFVQENLDNGTPKTSVEVLKDIQQIMYRTEDGFEVPVEDEEETY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9S4</accession>
    <name>A0AAD5U9S4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006195</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000052">
        <property type="protein sequence ID" value="KAJ3225797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9S4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990861">
        <property type="term" value="C:Ubp3-Bre5 deubiquitination complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000003">
        <property type="entry name" value="Nuclear transport factor 2 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="NTF2" evidence="5">
        <location>
            <begin position="25"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="394"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="221"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="466"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="272"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="466"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="480"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="505"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="524" mass="58242" checksum="2322B50A85A980AE" modified="2024-05-29" version="1">MTAVSAVSSFQPTTPTTPAVDPFEVGWLFVQEYYTFLNREPHRLHCFYNKKSLFIHGQEAEPAQQYNGQTEIHEHIQSLGFEDCKVLVSQVDSQASQNGGIIIQVLGEMSNMGGSSHKFAQTFFLAEQPSGYYVLNDIFRYLKEDIDNEYEESADPTHDTSNDAASNHRVNNSGVTDSNIDFHQQQQQPPLGLNQQLEQHNQQHAFTNGSLNESNSLAETANKQPNNLSQIKRSTSKPRSKSPVKTRTPKSPEPKEVPAEVPAVPTEENVPQNVVHQKLASTPQQPKSKPPVSASNKKQQQPKIEQRAADQPTAAINPAPASEPVKHSWAALASKPAQQQPVKSVQKPSQVEEPKEDVKVEGQKENFHAQGGRNQRNRQGEDGQQRVGDDKDKHSLYIKHLPEGTQEKHLRETFEKVGAVKNVELQGKSVACIEFVNLDPVAKCIGQQFICNGGTIVPEERRRQYGFNNNRNNRNNFGQGQRGGFKQGGQGYNNSNQNRGGFQKHGSNQNKSNNPQSGGANKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAT5</accession>
    <name>A0AAD5UAT5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003971</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000027">
        <property type="protein sequence ID" value="KAJ3226859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAT5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000383">
        <property type="entry name" value="Leucine-rich repeat receptor protein kinase EMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051716">
        <property type="entry name" value="Plant_RL_S/T_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48053">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48053:SF126">
        <property type="entry name" value="MDIS1-INTERACTING RECEPTOR LIKE KINASE 2-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042127374" description="L domain-like protein" evidence="5">
        <location>
            <begin position="20"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="37727" checksum="19929B5FE54A7AD8" modified="2024-05-29" version="1">MKVLGSNLSTFLLVLHVFAAVNITEINQQSHDCMVIYKWIPQIYPNNVADCCAITADSKDSTLVHITCDANKRVTKINIGKKYNPALTQIRGNWKSEASGILNAVLPPFLGLLTELTTFYVTDAFLYGQIPMEIGNLTKLQYFSVGYNSLTGEVPKNLFSNMKSLIALDISHNKLSGNIPNSFVGLPSLVSVQIGSNQFSGPLPDYSKLANVGLGPKYDIENGGGFLPICDFRNLGPTACVEFASDLTNKLPSSCILSTPPPKVCTPEQISPVETTKSIETPIFATTNPTPSPQGISDSLKIAIVAISIILFFTLAYFVSFRIIKRKNKVENERFQRERQIVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBG2</accession>
    <name>A0AAD5UBG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000004">
        <property type="protein sequence ID" value="KAJ3228243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBG2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="220" mass="25970" checksum="B02697336D93AB36" modified="2024-05-29" version="1">MSSINEHHDATQDYYSMENQLLRIYTFHTLITSYILFIIYILSILVVEILKYNARNLEDAHYSSNTIKEMLFSHPVQKNNDALLSERPVILYVEDNEKGKEALTEEPVSGDLEHLLSTKNDISEETKESVQRHSFYRIVEDFKEPTTEANDENPDLTLRHTNTLQTTIDENEDENWHDEKLLKMEKYDNYKENWQNVFIIYISTVFLSFAGIFLFSKRSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBH1</accession>
    <name>A0AAD5UBH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_006024</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBH1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PAPs-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="ACID PHOSPHATASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953:SF153">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041951762" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="691"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="59"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3228144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="806" mass="91477" checksum="C51E39BB10278B08" modified="2024-05-29" version="1">MSSVLILLLASALFTKTSSFGTKCRLKESDDAMKISSLPRTNEAVPRDLKMVFVGDQGINDNSYTVLKMIRDWNPDGIVQLGDFDYEDNPQAFMNMYDSTIPKHIPVFPVVGNHDIVRWETYSKLFKKRLEFSGALANCEGDLGINMQCNFKGLNLLLSGIGTMGRNHASFLNKTLTKAEDKGWNICCWHKNQRLYQTGDKQDETGYEVYDTCRRHGAMIFTAHQHLYARTKLMEGFETQVIAERKYYPQDYAGSTFVKRDFLDDEETIDVFRHHKNRKNKKVLKKNLYTKSTPRVSDNGSFDLLNLSPGFSFVTLSGLGGNSIRPWQDGLQLKEWWSANAAEDNNAQYGAVFCTFNINNDENLAKCEFIDINGKLWDKFYVNASKGRRDSFSSFSKNSAYRALNLNNAPQSNELNFPQIKLPDDTNSKTRFLEVSIDSKHDIITFEKRQETISILSIKDIDHAILKFPLAQKVGKSLNHNNSNSSLIHALHFKNLKLFNGERILKSHLQLMLSRPTNGGKNWKDSSLGIKIKVAGDEEEIIIDGDKEDWDVGEVWVSRDLSSIVNKVVKLQRFQDEELEFSVKLLIEGWTISKNAKGEHLVESRGVNGIGDDELSLCTSPTLAVILEKQRINTIPSPTYYKFSQSIQRNLFKSLSTATETATNIKAKLEKKLPEKETFKSISKKYGYTAFLVYTFLTTLLFTSVFSAITYSGLTPNEIEKKVKSFKDNYLPFLVSQSKEEQIESIDEESKIVSWFKKLGISENLATHLTNAVLAMTLTKLVSPLKIALSIAVTPSVAKRLKFLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XR98</accession>
    <name>A0AAD5XR98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002253">
        <property type="protein sequence ID" value="KAJ3198831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XR98"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="266" mass="29897" checksum="051553FD11A290F7" modified="2024-05-29" version="1" fragment="single">MESIILKLELLELETKKFNSQLKSLSYATKSLKTSVKIFETTNKRLFSNKKNSYQETISIYDQYFPDDGIKNSVVDQPLKEPATIKLADVNSTKPLAKLVDSSSESKAKITKTFKPADNSFKTIVKTKAASIKTQKNSIPVNYLTMAKAVIINNQQRNYDVTSQMIDKPNQKTTNATTIDIAKSKESTSLDIAKSSNESTTFSIPQRNASYDIKKLNLIPPKTYETSIFPERNSSKVTDNKLTEKNIKLSRKTLPTDTLIIDTSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRP4</accession>
    <name>A0AAD5XRP4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001743">
        <property type="protein sequence ID" value="KAJ3201337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRP4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="590"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="620"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="673" mass="68598" checksum="4AD462DDA8CD4492" modified="2024-05-29" version="1" fragment="single">TAKETIVASTTAKPVSTQDVSSTNTVVSTHAAESTGKETVASTTTKVVSTQDVSSTNTVVSTHAAESTGKETVASTTTKAVSTHDVSSTNTIVSTHVAESTGREASVASTTTKSVSTQDVFSTKLVQTATEITQTYEKTNSFITNILSTSTNEHNFNHGTEEVKLETISSTTSATTAKSTPLESTTFYVENSESTEVAYSNTRESTRSVHFATTNQESSTSNKITVLTSTTNAVSNPDVSSTSTVVSTHAAESTGKETVASTTKTVSTHVISSTNTVVSTLVAESTAKETIVASTTAKPVSTQDVSSTNTVVSTHAAESTGKETVASTTTKVVSTQDVSSTNTVVSTHAAESTGKETVASTTTKAVSTHDVSSTNTIVSSHAAESTGKDTTVASTTAKVVSTHDKSSTNTVISSHAAESTGKETTVSSTTAKAASTQDVSSTNTVVSTHVAESTGKETTVASTTKTVSTHDVSSASTVVSTHTAESTRKEIVASTTAKAVSTQDVSSTNAVVSTHAAESTRKENVATTTKTVSTHDISSTNTVISSFVAESTEKETVASITTKAVSSHNVSSSNTVVSTFAAESTEKETVASTSTKTVSTQDTSSTNAVVSTHAAGSTGKETVASTTTKAVSTHDVSSTNTVVSTHTAESAGKETVASTTAKVVSTHDTSSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS66</accession>
    <name>A0AAD5XS66_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein BCP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BCP1</name>
        <name evidence="3" type="ORF">HK099_001223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in nuclear export, actin cytoskeleton organization and vesicular transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001320">
        <property type="protein sequence ID" value="KAJ3204259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS66"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025602">
        <property type="entry name" value="BCP1_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261">
        <property type="entry name" value="BRCA2 AND CDKN1A INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261:SF0">
        <property type="entry name" value="BRCA2 AND CDKN1A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13862">
        <property type="entry name" value="BCCIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028983">
        <property type="entry name" value="BCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR028983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="284" mass="33439" checksum="E323FA3F2449FEC7" modified="2024-05-29" version="1">MENELKRKEVDSEESDNELMEIDVNFDFFDFKEVDFLGLKTLLKQSFSADHTLFNLSEISDLIIKQSNVGCTVKADDSTDPYAFISVINLNLHSSNESINQIKDYFLEKTRRNINMHKKLIELFDRKIDTNSNNPCVGLIFNERFINMPPQIFPQMLKMTLEEIEWAVEEGEKFNFDYYLVPAKIYEEIESKIDNEGNLIVMEETEPKKKKNKQSNTTTLYFQPEDEIFQEYCEIKCDFKFSNPNQESDSKRTFQDFGIEPSRRLLLIKSENLKKVLADVEMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSR8</accession>
    <name>A0AAD5XSR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Fumarylacetoacetase</fullName>
            <ecNumber evidence="4 16">3.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 16">Fumarylacetoacetate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">HK099_000625</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>4-fumarylacetoacetate + H2O = acetoacetate + fumarate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10244"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18034"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="3.7.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="16">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="4 16"/>
    <dbReference type="EMBL" id="JADGJW010001152">
        <property type="protein sequence ID" value="KAJ3206101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSR8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004334">
        <property type="term" value="F:fumarylacetoacetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902000">
        <property type="term" value="P:homogentisate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000004">
        <property type="entry name" value="Fumarylacetoacetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="entry name" value="Fumarylacetoacetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01266">
        <property type="entry name" value="fum_ac_acetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069:SF2">
        <property type="entry name" value="FUMARYLACETOACETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="Fumarylacetoacetate hydrolase, FAH, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15 16" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 15 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 16" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 16" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Fumarylacetoacetase N-terminal" evidence="18">
        <location>
            <begin position="11"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="17">
        <location>
            <begin position="112"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR605959-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU366008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3206101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="378" mass="42171" checksum="0A3590F1B8267930" modified="2024-05-29" version="1">MNTNELDFSIQNIPFGIISSASNSKKRVASAYGSNAIDLTLVKFNGPLLGNGVAEKVFNQCFLNDFMELGRPAWREARQTLQNLIKENKLPAESLISLSQVQNHLPAKIGDYTDFYASKEHATNVGTMFRGKDNALMPNWVHIPVGYHGRASSVVVTGTNLKRPSGLILDPTTKLPYYSKSKKMDIELEVAFLVGKGNNLGEPIKFDDSEDHIFGMVLMNDWSSRDIQSYEYVPLGPFLGKNFGTTVSPWVVTLDAMEPFRTSQPHQDPKPADYLTGSSVHNAGDAYDVNLQVYYKTPKSKDTLICESNLKYMYWTFKQQLAHHTVNGCNMNTGDLCGSGTISGPTENSFGSLLELTWNGSKSLNIDGEERKFLEYWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTB7</accession>
    <name>A0AAD5XTB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable ubiquitin carboxyl-terminal hydrolase MINDY-4</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Probable deubiquitinating enzyme MINDY-4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_007974</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MINDY deubiquitinase family. FAM188 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000829">
        <property type="protein sequence ID" value="KAJ3211532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTB7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025257">
        <property type="entry name" value="MINDY-3/4_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059022">
        <property type="entry name" value="MINDY4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039785">
        <property type="entry name" value="MINY3/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12473">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12473:SF8">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26038">
        <property type="entry name" value="Dimer_MINDY4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13898">
        <property type="entry name" value="MINDY-3_4_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01174">
        <property type="entry name" value="DUF4205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Deubiquitinating enzyme MINDY-3/4 conserved" evidence="12">
        <location>
            <begin position="232"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3211532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="611" mass="70130" checksum="CE358BCB844C80E0" modified="2024-05-29" version="1">MNFILSETLIREFLASHSIYKNTYQQFVVDSKKNLEKSPTSSIDEKIVKRSHLAKKLGIYNLYNQNKASDNPKKSIIELVVNKLMSNTDKEDKCEKVSNSSLFNSERLESKSDVEKKEWSSSVSSLKKNSTNSLDTITSKKKKNSTDSFIEGKNMADVNNQALFTNSRESIYNDLKKVNINPGEKHMFSEEIEEIEDFEDTDFDFKPVQKNLNSKSKWETYQIRPELALELRKVIFDHSSVGEKILLSFNEEWKFKGFEFSENPELRYGIVQLKGGPCGLLAAVQAHVLKHLIFNSSVSYNNFNRGFLRPKQIDTERALIESLTEIIWRCSIDTGYCLVAIYNNISKNSKNSFLNAPGYKLDGFTEKMEITKILERSKLKQFLTENILTFTKNEKDNFGLIQLLYSAVLTRSIKNITKKDFDDSFLEKQKEKNISSNFKNFSSSFIGNHGYCTQEMINLLILGRATGNVFDGTINLNGENDKETKILRGVDGISEYGYLTLYEHYKSIQVGTVLKNPKYPIYLVCSESHFTVIFSSNTALSSSTKGDMPKRFDLFYYDGLANQDQEIRLTIDTSHKHLQVEKDEFTPPLEHCIRTKWPNAVIEWNGTDPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTE7</accession>
    <name>A0AAD5XTE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000796">
        <property type="protein sequence ID" value="KAJ3212081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTE7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="20948" checksum="3DB9B2B2D6E93939" modified="2024-05-29" version="1">MCDLTDLGEDICTNLAIPKTSNNRDNHVKINQPVKKIIFEYDNTDIDENLVSTSSQAKEYMNLKSEVEEEEVDINDNFSAIKEKSTFKPLSKYLRQNKFEDFALAVKTGKDAVLSRVPIQLVTFLSNMGNIMYIGETSNITVSDINVEDVCTDLYNNFTLKPDGWDDILNNVRKKSNNGVDGPKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTE9</accession>
    <name>A0AAD5XTE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000822">
        <property type="protein sequence ID" value="KAJ3211641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTE9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3211641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="146" mass="16862" checksum="AAA54D496499D7AF" modified="2024-05-29" version="1" fragment="single">IESYLIKINQKNHNFNLNIQQIRNLTPLKKNPSQIEDLATLNFSSVPNSASQNQDFNSNEVNTPQQQQIYQQQPNNTPYFLQKENNSAYNSTSNLYPDLRANKNYHNNTNHNTDNLVKCNTDSSANVQHIVEKDKMIVELRDTVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTM9</accession>
    <name>A0AAD5XTM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_007567</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000745">
        <property type="protein sequence ID" value="KAJ3213103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTM9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF0">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3213103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="482" mass="53125" checksum="5DC9F0ECA7E8F18F" modified="2024-05-29" version="1">MGRTIKSIAHAQLVQPFIDLHRFFVESGKQVGLIFVIITAGIYFLQGFRDYALGDGIIWMFSEEFKLTTAEITNAESNIMIPWNIKMVYGLIFDSFPIFHRHDQPYLFLAAALQFIGFLGIAIKPMSSTAGAAVAFFFMFSMGIACTDVIADAMIVKKAKQLGKAGGANFQTLCWISLQVGILIGTPTSSTIVGDGPGARDLYSYVYTVTAGLVFIGAFFLTEKPSKVKTGPKFLFNQVRLLLKAALFDMRIFLPILWILLNGAVVANMDSPMALWKKQEIKVNPAMQGYISTAGTLASILGMTLYARYFKETSFRKILFWTQLLLGVFSFLDIMLVKRWNIAIGLPDLPFLFGGRILNYGITYVQQVPFLVMAAQLCPDGIEATFFATLMSCSNGGVNIARKWSAPLQAALGMVPREVDGKDVIDFKNLEIGLWITLGGYILGGFLVFILIPNTAHIFPEKEAAAEAEFAAAEKEKGDTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU74</accession>
    <name>A0AAD5XU74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acyl-protein thioesterase 1</fullName>
            <ecNumber evidence="4">3.1.2.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Palmitoyl-protein hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_006558</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19233"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="3.1.2.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.22" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000575">
        <property type="protein sequence ID" value="KAJ3215023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU74"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000276">
        <property type="entry name" value="Acyl-protein thioesterase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF17">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="15">
        <location>
            <begin position="7"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3215023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="228" mass="25414" checksum="0367CDEFA51F8679" modified="2024-05-29" version="1">MSSLPAKILNAKTQHTATVIFLHGLGDSGHGWAPVAEMLQPHMKHVKFILPHAPNKPVSLNSGMLMPSWYDIYSLTDRDGRQDEEGLLDSVKEVRNFVTKEIDSGIPSERIVVSGFSQGCAVALLYAALAPFKHAGFMGLSGYIPLEKKLIATEGNFLKKLNFQTPVQLYHGEADQVVQLQWGRNSYELLKKLGFEKVNFTTYKDMAHSSSDEEIRDVANFLKKVLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUN2</accession>
    <name>A0AAD5XUN2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Diphosphomevalonate decarboxylase</fullName>
            <ecNumber evidence="3 13">4.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MVD1</name>
        <name evidence="16" type="ORF">HK099_002352</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:23732"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57557"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the diphosphomevalonate decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.33" evidence="3 13"/>
    <dbReference type="EMBL" id="JADGJW010001774">
        <property type="protein sequence ID" value="KAJ3201151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUN2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004163">
        <property type="term" value="F:diphosphomevalonate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000018">
        <property type="entry name" value="Diphosphomevalonate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.890:FF:000005">
        <property type="entry name" value="Diphosphomevalonate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029765">
        <property type="entry name" value="Mev_diP_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053859">
        <property type="entry name" value="MVD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041431">
        <property type="entry name" value="Mvd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01240">
        <property type="entry name" value="mevDPdecarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977:SF3">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18376">
        <property type="entry name" value="MDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22700">
        <property type="entry name" value="MVD-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-1207">Sterol metabolism</keyword>
    <feature type="domain" description="Diphosphomevalonate decarboxylase-like N-terminal" evidence="15">
        <location>
            <begin position="8"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Mvd1 C-terminal" evidence="14">
        <location>
            <begin position="189"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3201151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="389" mass="43313" checksum="8E7DC9DF6A563857" modified="2024-05-29" version="1" fragment="single">MSLITCIAPVNIAVIKYWGKRDQELLLPTNGSLSVTLSTEDMHSKTSVKFSTGNEDEVWLNGKKQEMNKRFKNVLSKFKQLRKEEEALNNLPKISGKYILVESENNFPTAAGLASSASGFACLAFSLAKFYALPLNDTEISKIARIGSGSACRSIFGGFVAWEMGSMKDGSDSYAVQIAPETHWPEMEALILVVSDVKKHTSSTSGMQTTIETSELVAQRINHSVKQRLHDMITAIQTKNFDSFAELTMKDSNQFHAVCLDTFPPIFYLTDISRKIINFIHVYNKVTSDGINLYKAAYTFDAGPNAVIYTLKKDIDQLMKFINFFFPPPEDNELKNYYRGSFGSDFTLSEKEQSIALEITKLGINRNSGSLLNGIIKTKVGEGPKVIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUS6</accession>
    <name>A0AAD5XUS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005701</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000458">
        <property type="protein sequence ID" value="KAJ3216832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUS6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="9"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="228"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3216832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="455" mass="51154" checksum="DAC3BDA7DA7B0FED" modified="2024-05-29" version="1">MTPIQSETFNLCLTEKDILAQAKTGTGKTLAFLLPTIQKILNNRRLKNENVSALIIAPTRDLAQQIHIEVQKILQSIPEIRAQIVFGGTAKKVYNDVKELKKTKPDIVIATPGRILDILENYSDVKSNQFKYVSTLVFDEADRLLDEGFLPACQKILTHLSNVKQKGQILMYSATISKDVKIIARNLLKPDFKFISTIDNSDTPTHLSITQTSLLVPDEDIYYAAYSLLKNYMEANKNHKIICFLPTARAAQVSALLFSNLFKNISVLEVHSRMVSSKRENSVQKFRNANEAIIFSSDVIARGLDFPNVGLVLQIGIPQNLDQYLHRIGRTGRAEAKGSAAIIVTDLEQNFLKKLHLSNLKIVEESVSFSPRDVALVKTALENVPLERKEQAYRAWLGFYKGFLKEFGVDLDTLVSRANNYALNVLGCVEVPKINWKLESKMGLKNVKELNRGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUX7</accession>
    <name>A0AAD5XUX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001498">
        <property type="protein sequence ID" value="KAJ3202944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUX7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="148" mass="16961" checksum="FBC71B900738C850" modified="2024-05-29" version="1" fragment="single">MISQQNSEYEDELVRITKDLDFRFGDSLPCNDTKVNFVSVRSICHKNIESIVNQCAYVASRIKCTVELIGVELNKNLDFKVGIIYPDILPKEGVEFLGNFILKHLLSVKLICKSDVIIYTKRKLTKEELQPITQDCQITDDYSKLQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV29</accession>
    <name>A0AAD5XV29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WD40 repeat-containing protein SMU1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005307</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the WD repeat SMU1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000406">
        <property type="protein sequence ID" value="KAJ3217881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV29"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054300">
        <property type="entry name" value="OB_DPOA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045184">
        <property type="entry name" value="SMU1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054080">
        <property type="entry name" value="TPR1-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22062">
        <property type="entry name" value="OB_DPOA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21889">
        <property type="entry name" value="TPR1-like_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="11">
        <location>
            <begin position="666"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="844"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="887"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="929"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="971"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="1013"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="1074"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="1099"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="14"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3217881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1132" mass="127747" checksum="24222D775AE157C7" modified="2024-05-29" version="1">MSFNRESLLSLIAPSKRPLRQKNDNSQHFRSSTYTNSTPTKKFSTSQIAEAEAKKITPYKESPSKPSVKYVHRADSGKILTKLNDVPYKKKSEESDFSVAITSFVNVEQRKCYLNSLYVMGDHFDELLNNFKTNYFKDLVFTQNPSQTCGENVTVMGRISCDSYEFDAKLNQSSCLLETSRELNNALKLILNFEDYLSKNGVLRLFQGQIIALEGVLENNEQCKSNKLLYLSYFEFSVLVSKIIYPPFPELPNTPVVELKKLYNDRKKGEPSNIFVASGPFTLEENLFFEPFEEFTLKVIEEKPNIVLLLGPFLDCNHQKIVDGELDLTLEEIFSLEISSRLNRMLNSNAKLKILLFPSTQDAFHSYSLFPQPAFCTGTATEENLIKSELGIINDRILLFSNPCVFGVDEIVVGVSTYDSIKEIGGNEVSVNVDLSAETIIGGRISALYRHVLEQRRFTPFSPAKIDVSISEPELTACDLLIIPSVLKPTVGTVNGVVCVNAGKLSIGSSGGNYCRISTYPMELDSEVQSIDEEDLATYHYFKDRMCSNIIGNHAITAAIITAYSRINIDNSNENEVQENQSENQIDLTNKEENKNLTNQVKFEKIKHVGLDHTKIKPSESLFNPSEVKEDIIRIISQYLSDEGYLASKLVLLDEANLKSQEREERILDAKRVKKAILEGDWPEVDRICSKPLVKNQKSFLYHVYKQQFLEYIERHEVQKAFTHLTKRIKPLENLQTTQNEFKDLCYLLTAKTLHDAPSFRNWEGITTSRENLAEQFQTMIDIENNEKNKSVFVPPQRLLTLLRQAVAYQIDSSRYQPQIAPKISSILEDYVSLIIPNKLRHTFYGHQGNVKCVGFVGDDGNMLMSGSSDNTVRIWDTESSNCLGVLEGHSSRVWDVDSNKSGEMVASASADGTVKLWNPKNFELLTTLENSNSDVYTVKYHPAGKHLVTGAYDKVVRLFDIERGQVIKTFGGHNLSISKCIFSPLGNLLISGSKDSTIKFWDIVSGLCIKTISSHLGEVTSVEMNSNGTFLLSSSKDNSNRLWDIRMIRPIRRFRGHQNTSKNFIRSGFAGDSLVIGGSEDGVIHLWDLEKGDILEKLEGHQGIVYNSVFNARQSLFASCSDDQTVKTWYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV87</accession>
    <name>A0AAD5XV87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">beta-ketoacyl-[acyl-carrier-protein] synthase I</fullName>
            <ecNumber evidence="2">2.3.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003299</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.41" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010002182">
        <property type="protein sequence ID" value="KAJ3199129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV87"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF336">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="4">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3199129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="250" mass="26642" checksum="5F67CBD8BEFD848D" modified="2024-05-29" version="1" fragment="single">GPNHAVSTACATGAHAIGDAMRFIQYGDADVMVAGGCESSISPLGLSGFCRAKSLSTNFNENPTESSRPFDEKRDGFVMGEGAGVVILEELEHAKSRNAKIYAEIKGYGLTGDGYHYTSPPDDGSGAARAMRRALEVAQVRIEDVDYINCHATGTPQGDLAENRAIKSVFYNNTKVKVSSTKGSIGHLLGAAGSVEAIFTILSLYNKVLPPTLNLTKVSDEKEFSLDYIPLVARDEKNLKVALNNSFGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV98</accession>
    <name>A0AAD5XV98_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">choline-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="8">2.7.7.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003193</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.15" evidence="8"/>
    <dbReference type="EMBL" id="JADGJW010002125">
        <property type="protein sequence ID" value="KAJ3199388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV98"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004105">
        <property type="term" value="F:choline-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031210">
        <property type="term" value="F:phosphatidylcholine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045049">
        <property type="entry name" value="Pcy1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739:SF13">
        <property type="entry name" value="CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739">
        <property type="entry name" value="CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="10">
        <location>
            <begin position="86"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3199388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="28594" checksum="B52D5B4B6B049FD4" modified="2024-05-29" version="1" fragment="single">MKNKTTQVHSPKKNKKKVPVEDKKKDLSQLDEVKKSEDDLNQPNEKKDLRKSKIFKVDGKEVDISRWASIPENLMDPPNGRPIRIYCDGIWDLFHFGHAQALEQAKKLFPNVHLMVGVCNDELTHTKKGKTVMNENERYCGVAHCKWVDEVVKDAPWLVTQKFLDEHEIDYVAHDDIPYKADDCDDVYKFVKDQGRFIPTARTVGVSTSDLITRIVRDYDAYVRRNMDRGASRKDLNISFFKVNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVY7</accession>
    <name>A0AAD5XVY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Gamma-cystathionase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003941</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000268">
        <property type="protein sequence ID" value="KAJ3220850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVY7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000046">
        <property type="entry name" value="Cystathionine gamma-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000008">
        <property type="entry name" value="Cystathionine gamma-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF15">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3220850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="365" mass="39337" checksum="958EED142F18E6B2" modified="2024-05-29" version="1">MGRINYEGLGFFGTKAIHAGQEPDVATGAVIPAISLSTTFAQTSAGNPISTFDYSRSGNPNRNNFETAVAALEHGRFALAFSSGSAVTAAVTTMVTSGSHIISVNDVYGGTSRYFRKVANRSNIEVDFVDLNDPNNIKGHLKPNTKFVWIETPTNPTLRLVDIKAVADIVHQQPGNPLLLGADIVVHSVTKFINGHSDVVMGIAVTNNEQYFEELKFLQNSSGACPRMKKHEENALEVAKYLENSSFISEVIYPGLPSHKQHNLAKSQMHGFGGMLSFRLKNGNLSSSNKFLQNLKLFTLAESLGGVESLVELPAVMTHAALTAEARNTLGITDSLVRMSVGIEDSVDLINDIASALNAVFVKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW44</accession>
    <name>A0AAD5XW44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cobalamin-independent methionine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine synthase, vitamin-B12 independent isozyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">MET6</name>
        <name evidence="18" type="ORF">HK099_003673</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="14">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the vitamin-B12 independent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.14" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000242">
        <property type="protein sequence ID" value="KAJ3221242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW44"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071265">
        <property type="term" value="P:L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03312">
        <property type="entry name" value="CIMS_N_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000002">
        <property type="entry name" value="5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000003">
        <property type="entry name" value="5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00172">
        <property type="entry name" value="Meth_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006276">
        <property type="entry name" value="Cobalamin-indep_Met_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01371">
        <property type="entry name" value="met_syn_B12ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003556">
        <property type="entry name" value="PRK05222.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30519">
        <property type="entry name" value="5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000382">
        <property type="entry name" value="MeTrfase_B12_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 18" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 14" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE N-terminal" evidence="17">
        <location>
            <begin position="9"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Cobalamin-independent methionine synthase MetE C-terminal/archaeal" evidence="16">
        <location>
            <begin position="447"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="715"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="452"/>
            <end position="454"/>
        </location>
        <ligand>
            <name>L-homocysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="452"/>
            <end position="454"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="505"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="536"/>
            <end position="537"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="582"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="620"/>
        </location>
        <ligand>
            <name>L-homocysteine</name>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="620"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="662"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="664"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="686"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="747"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3221242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="773" mass="86745" checksum="C3B8EBCD0FF77361" modified="2024-05-29" version="1">MSAKSLVTATNLGFPRMGANRDLKKSIESYWSGKTDLQTLLLSAKNLRSHHWYLQQTAGISNGHIPSNDFSFYDHVLDHSFMFGVIPEQYKSIQNKVDQYFAMGRGRQQDGVDVPALEMKKWFDTNYHYNVSTLSPSTEFKLTPLIGDKVKPVQEFLEAKAFGIRTRPVILGPITYLLLQKSAKSAPSDFDLLSLLPKLLPLYEQILAELKSAGAEWIQFDEPALVMDLPASVTTALKTAYERLHESQPYLSLLVATYFGTVQEKTINTVLELPISAIHLDIKAPEQLDVVLSKIPSGLVLSVGVVNGRNVWKANYEKQFALVNKAVSALGKNRVFVAPSCSLLHTPHSLSSERKINSEIRNWMSFSTEKIDEVVTLTIAANHGIAKVQGAFDANLKANKFREASPLIHNQKVKQAVSNISPSMLKRSEAFEARNRAQQAKLQLPLFPTTTIGSFPQTKEVRVARQKFKNGEWSQEKYDEFIAAEIGRTIKIQEEIGLDVLVHGESERNDMVEYFGENLEGFIFSENGWVQSYGSRCVKPPIIFGDVSRPHPMTVKWSAYAKSLTQRAMKGMLTGPVTILQWSFVRDDQPRKDTTFQIALALREEVVDLEAAGMSVIQIDEPAIREGLPLRNSEQEAYLKWAVDAFLISSTGVRSDTQIHSHFCYSDFNSIFTAIKKMDADCVTIENSKSDLKLLTALETFGYSSGIGPGLYDIHSPRVPSFDEMKERLEAILTYVKKDLLWINPDCGLKTRGWTETIASLRNMVEVAKAMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWD5</accession>
    <name>A0AAD5XWD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Transcriptional repressor NF-X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">NFX1</name>
        <name evidence="14" type="ORF">HK099_000761</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001192">
        <property type="protein sequence ID" value="KAJ3205589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWD5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034078">
        <property type="entry name" value="NFX1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360:SF12">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR NF-X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01422">
        <property type="entry name" value="zf-NF-X1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="110"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="113"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="38"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3205589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="461" mass="52101" checksum="CE813A87AB4675E5" modified="2024-05-29" version="1" fragment="single">MEATPIDQKLYCQRGSSSKPRGRGRGRGGYRHQKFGSELSTSNQSPDQDSSSIGKYDNYSNEESHNSNFYHQKKFNGGGKTHRKNFKPHDNGKVQKGKMEDMCHSLSNSSYECMICYDTVKIKDRIWDCETCYAVFHLKCVQTWGEKSFTEKSGDAQGWRCPGCQGLTKDIPTSYKCYCKKVDQPTFTRFITPHSCGQTCGKERDCPHNCNLLCHPGPCPECQSFSAPTFCYCSKKKFIIRCHEMKDLNRNKSCGELCEKTLNCGIHQCQEICHVGECPPCEVLINQNCFGHENTRTVTCGDAKGNLHYSCGDVCNYQFNCGFHSCQEGKLESIHIVKIFFFSITLVCHPTEFHPTVCPLDPSLNLRCCCGKEDVNTLTPKRTLCTEPLVCCKNRCSKELLCGHECTAKCHDNECPTCRKKIDLQCRCGSKSFQVSCAELKRIGDTSEYELPQCNNVCNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX10</accession>
    <name>A0AAD5XX10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001381</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001382">
        <property type="protein sequence ID" value="KAJ3203768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX10"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018810">
        <property type="entry name" value="UPF0662"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086:SF1">
        <property type="entry name" value="CU(2+) SUPPRESSING AND BLEOMYCIN SENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086">
        <property type="entry name" value="UPF0662 PROTEIN YPL260W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10303">
        <property type="entry name" value="DUF2408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="121" mass="14361" checksum="D04777B57E6A5EF5" modified="2024-05-29" version="1">MTWITCYRLVHHLQQKSEETLPIHQSLIQIYNQLYTLKSCLSELNKWKVVLTERELIPYQMKLAKLDNKRVDGKFEVNGTIPEGQGELHGLLNECYEGLNQLKLRFIEKLEHEEEDDDDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXA1</accession>
    <name>A0AAD5XXA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001215">
        <property type="protein sequence ID" value="KAJ3205310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXA1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025340">
        <property type="entry name" value="DUF4246"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049192">
        <property type="entry name" value="DUF4246_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049207">
        <property type="entry name" value="DUF4246_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119:SF1">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33119">
        <property type="entry name" value="IFI3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14033">
        <property type="entry name" value="DUF4246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21666">
        <property type="entry name" value="DUF4246_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4246" evidence="2">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4246" evidence="1">
        <location>
            <begin position="71"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3205310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="522" mass="60777" checksum="6F947415C74CE8DD" modified="2024-05-29" version="1">MQKNIADQNKEEFRSHVTDFTYEAITTYELKLLSIINQIIEKPFWYQKINNQEIRSKWYKELQDSEQFPVKMIDFALEELLYKANNEFFVKKLPDGACITCGPVEETFISDNLINNELLEDLKKCVSVLENVPDSEKDWHPYSNNLVLDLVHPSLYCIKSGKTLSKDGNTIMLSADGNDVFQWIPSDVFIDADYSAKLLSPINSLHPEIHKNTTEVIMKIFSKFIPMFENMLNVILNGPPGSRIKLPYTLWDEFDESEPEGVEAQEEYYRRMDEYHDNRPLLDPELNDFKPYIIKKPYSLLNKHVQVIVKLANIQLTPEKPKYDGGVWHCEGTQHENIVSTGIYYYDNKNITQSKLSFRVGVFEPWYEQGDNRGMGLGYGLHDEELLIQPVGSIISKEHRSIVFPNTMQHLVEPFELEDKTIPGHRKILAFFLIDPTKKIHSTGDIQPQQLNWTLDMLQEILKNKLPPEIILEIVKRVDGLISLETAKEWRLELMEARKASNEMFYDHDGPVFLRHFSLCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXE1</accession>
    <name>A0AAD5XXE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein phosphatase 2C 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PTC1</name>
        <name evidence="4" type="ORF">HK099_007674</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000766">
        <property type="protein sequence ID" value="KAJ3212709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXE1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF837">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="70"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3212709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="36840" checksum="A46B65F8E9B83909" modified="2024-05-29" version="1">MQRNITESPASSLTKFEDEDLDDYSATLKAGTETMNQFESSDDDSSEEELEEGNNSLIRDDSVQKSSGFSIGFAEDKNKKYRRSMEDSHSFFYNFGNVLGSGWFAIFDGHAGKSTAEHCGLYLHENFQKNLKESPDIPIPELLNKTFIQTDKQLSEKKGLFSGATAIVAYIRNEIKNDKKSRVLYTANAGDSRAVLCRDGVAVRLSYDHKGSDNQEVKRIMEAGGFVMNNRVNGVLAVTRSLGDISMKEWVIGSPYTMETVLKPTDSMLILACDGLWDVCSDQTAIDLIKDESDPQEASSKLLNYALQNMSTDNLSILCIKFDKDFLVRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXK6</accession>
    <name>A0AAD5XXK6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_000382</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000109">
        <property type="protein sequence ID" value="KAJ3224005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXK6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.170.10">
        <property type="entry name" value="p53-like tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024205">
        <property type="entry name" value="Mst1_2_SARAH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036674">
        <property type="entry name" value="p53_tetramer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011524">
        <property type="entry name" value="SARAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF2">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11629">
        <property type="entry name" value="Mst1_SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50951">
        <property type="entry name" value="SARAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="SARAH" evidence="11">
        <location>
            <begin position="525"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="253"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="421"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="470"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="577" mass="65017" checksum="0D6634B3E30DC4D1" modified="2024-05-29" version="1">MNEHFVLTPEELNEDPAEIFTVLNKLGEGSYGAVYKGIHKRTSTLCAIKMIPIENDLDDSVKEISMMRNCNSNYVVHFYGSFLNDNYLWIVMEYCGAGSVADIMRLCNTVMTEEQISVICSFTLSGLSYLHSYRKIHRDIKAGNILLNTVGEVKLADFGVASQLTDSKTKRLTVIGTPYWIAPEVLGDQGYGIEADIWSLGITCIEMAEGRPPYHDINPMKHPFIVESPGLSIMTDIVTEALEEIGRVGLVNDDDDIEDDFDSEMDLESRNTSDNESESDKLIQRNNDVYSSDEEEDVNIDTATFDDSTMKAVQKDVNNLHVETEVEVLSVEDTENNKAETDDSKPFLEEPKNSTEYEKQRYVEDSDAEGQKKSIQIGKKVNINNSNNNDENIFTEFDSGTIKKVDLTNQRKEGKINFMQNDQLTNSNNQFFNDSNTDDKTNSPTFNNNDNLDQISFPVQSLDYKNTIKPINESKQPKPKGNLESTHTTSSAISASNKAFKPTSTENNTNSRKPKALHEPPDLYDLISNKLSVEELKNLLRALEINFDVEFNSIKSKYGKKREPLVEALILKQQQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXK7</accession>
    <name>A0AAD5XXK7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein kinase C</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">PKC1_1</name>
        <name evidence="23" type="ORF">HK099_000352</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000108">
        <property type="protein sequence ID" value="KAJ3224026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXK7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20822">
        <property type="entry name" value="C1_ScPKC1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05570">
        <property type="entry name" value="STKc_PKC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000465">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000103">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="REM-1" evidence="22">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="18">
        <location>
            <begin position="274"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="442"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="20">
        <location>
            <begin position="516"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="837"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="21">
        <location>
            <begin position="1112"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="626"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="703"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="584"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="626"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="654"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="680"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="703"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="716"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="866"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAJ3224026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1191" mass="135763" checksum="C71B2FF4834CA6DF" modified="2024-05-29" version="1">MSLPFISSTSKQDETKIQDLIQRIQIEKKLVEGAQQMLKKLTDSDAKQLCHLNLIQSQQKVEFLETELKKLTIKFDKTTPDSASTPFPSSAVSNTSTGKESILNNEKFVDTTEQSVCNEKKPSNSTVFGNLLSSFGKKDKLNKNFGSNSFLNSASTRNSVNTTNNAVLDQNLSALEESKPENFTKLDYLKVDTPLRTEKVNFRLYHIKGKLDLEQKVKAGTSNLVEAMKKNPNSDQKLSNELQFGLEQKIMEASAKIGFLIKSVQQYSGLVVFRDEDEDDVIPFRSARRSGRLKVKLLGAIGYGKRSSKDDFFCVIKIDSIVKATSKPSSKQKFEETFDIEVSKAQEVEISLYEKVSGGHQRSPLLSFVWFSISDLEEDLAQKYDQNYSGKKIDEFKEMWLDMEPGGQVLCKMNFASVCRTTTNSNQVFRRRAVQKLYPRNGHKFAATQIYGVSQCAVCNEFMTSQNYSCQNCQYACHPHCYNKVSTKCISELEYSILKAEGGDTNTGELLKYNIPHKFQQTINLSPNWCGHCGYILPIGKKVSRCTECQKNSHKNCSNLIPNFCGLNPNMANALIAAWDDADKKQSQRELEEAELEASKVREMVQKENNLIIKTLPENKELFTGSHQNEQESNQLNSSKKPLSVTPPLRIDSRNWNEVSQNQISSLQYPRTSKFPDIPSASSYTDNGGTETAFQQNLVQGPQFSQNQQRHSQSQNKTQEQYSQQNTNFSIEVRECDEKVQQNAVLKDYSVSPVHHVSQMQQQPEQVHTEFQAAREKVLAQYQQQRLAARREENNGLEYQRKLAQQKLLEHQKSILVNNAKPKRRQHVVERVTLNDFHFVSVLGRGAFGKVMLATEKQTKKLYAIKALKKEFIIQSDDVKSTKLEKRIFQVASAAHHPFLINLHSSFQTESRIYFVMEYISGGDLMCHIQDKKRFPSARTKFYACEVLLALEYFHKNNIIYRDLKLDNILMTPEGHIKVADYGICKDNIGYGVTTRTFCGMLLIIWVFTKTKLGTPDYMAPEILLSNRYGRAVDWWSFGVLIYVMLVGKYPFHGEDELQILDAILEDSIVYPPNLPRETFAILNQLLNRNPARRLGGGKMDAEEVKKHPYFNGVDWNAILSKQIPPPWKPTIKSPTDVSNFDSEFTKEKAVLTPINSVLSQVNQDEFKDFEYISEWAAAERLKAKSMFHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXV8</accession>
    <name>A0AAD5XXV8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000954">
        <property type="protein sequence ID" value="KAJ3209189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXV8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="88"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="367"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="582" mass="68873" checksum="79EBAFEE8989304D" modified="2024-05-29" version="1">MRIKDQKIISTVEELDLLQFHNKNLIKKIESLQQEVKKNFLPVSLSKSNSQKNTNFSNPNTILQQELSGKILENEKLQNYIFDFSNENKELKSNLIQFEHENNSLKSSLEKFEKDNENLRNQVKTKNLKIEEFQRIENQLKKKNQDGNLLKNDNLNEIIVEEEEKSLQILNKSINQFYKAISSLLSFKNLVKEEFNLDIRQSDQKLNFFSDLDHTISEATLKNLKEISITFDNFLLSFKTFFEKEEKKFNDNPNQDLAMELEKCNFLLNLMIKDLESFNFYFKNILEWMELKVNSVKKKIHRDDDEVDNIPQEQKEELNFVNFHIVYYVSKLNLSMKGLYRHALVYISLKAENEEDLHKIIKSNKILNCLQSAFIEEEENKSEIKEEVISNLIKTRSLTFETIKSRDENIFKTLKLIKIYLKFFFKEDELNLLEYYRLLNLNFKNFKALKKFNVDIIHQLKILKNTTKSETSNNLNEQKDDILKKKLTNVTVTKKVDSQIQTDEVDDDDIDDEEEISEKQQNRSVTCKSIEIQTEEYISNDDICVDNDTSLYGNSVSEIRLNQLLLKVQELDSFLIKNNLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY05</accession>
    <name>A0AAD5XY05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008266</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000895">
        <property type="protein sequence ID" value="KAJ3210366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY05"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12344">
        <property type="entry name" value="RRM1_SECp43_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12345">
        <property type="entry name" value="RRM2_SECp43_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF10">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="91"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3210366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="278" mass="31325" checksum="D2E48096CE180AED" modified="2024-05-29" version="1" fragment="single">MGDLLEWMEETFIAGIWFQYGEPVFVKLIKDKYSNGNAGYCFVDFTHHEAAAICLNTLNGSIIPGTSRLFKLNWATGNVLNLTGEIRPKEYTVYIGDLAPEVNDFLLLSAFQPRFRTIKHVKVVIDHFTGTSRCYGFVRFADENEQQRAIMEMNGVYIGSKPILVSTAVPRARMLGDHSQSSGAIPLTIAPLPKAVLAMPKPKPPQPLLLNQPPAFASNDYERGGKFGVDIDNCLRFGPTFQYFIVKNEPNQDLLKKKISINDLNVRYYSLEEEFYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY25</accession>
    <name>A0AAD5XY25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Copper chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CCS1</name>
        <name evidence="1" type="ORF">HK099_006806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000061">
        <property type="protein sequence ID" value="KAJ3225435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY25"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006801">
        <property type="term" value="P:superoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="217" mass="24139" checksum="E1713501205ACFE9" modified="2024-05-29" version="1">MTKNELHYEIAFNKAKFLPLDGVELIKETSNTLQLKSIFHPTALLKKLDYLNPVIKSVSNNSINLNAVCIFEHFSGVKPGKWQQFDNKGLARFIQTEENVLILDLSMSGLKKNAEYSVMIFEAGDISSVPDSLGSCLKNLFTFKSTGDGELLIVKEIENLFIYDIIGRSLVVDEKNVGRNASSEAIAGIIARSAGFFQNEKMVCSCSGNTIWQEAKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYP8</accession>
    <name>A0AAD5XYP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Guanine nucleotide-binding protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GPA1_8</name>
        <name evidence="6" type="ORF">HK099_003701</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000245">
        <property type="protein sequence ID" value="KAJ3221196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYP8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000720">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF360">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="224"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="293"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="443" mass="52054" checksum="7605B70C67CEC0A3" modified="2024-05-29" version="1">MYMEDIDVNVTELEEVGGVNLTEILIDSPAKAKKRNSSIDKILKMQVQKEKNSSTLKLLVLGSGDSGKSTFVRQLRLSYTVSFTSEELSFFKNIIYLNIFYSLKTLLNGLEKLKLNPNPSQEFYDNSLAIKQHFQSDEKTLPWDIIQLFPVIWNEEIIKECFARREELDEDIQDTMPYFFDELKRICSKNYEPLDQDVICTRRKTKSVTETTLHTKKYVMKIYDVGGQRSLRNAWVSFFDDVNAIVFVAAISCYDLLMEEDKETNRMEDSVKLFGVIANHPMLAKSQIILFLNKMDIFKEKIKTVPIHKYFPAFQGEQDEKACKSFFKNLFVQSTTREMKYIFYTTNTDSQIMKKILLSVRNKNQLLNEKDIEMLRYYSVRELEGLKLQEIKNKFNKRINENLRQVFRNHQDFEEDLVEIDDEDANLSDDQIFNVFDDDIEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ62</accession>
    <name>A0AAD5XZ62_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL23m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ62"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059">
        <property type="entry name" value="RIBOSOMAL PROTEIN L23-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="98"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="145"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="160" mass="17977" checksum="982D361BA914DB7E" modified="2024-05-29" version="1">MSAFNTKLTQLYFPNINFVLVRSHHPPHQAVFKCPKSLNKIDIKNYLEALYKVHVTDVRTLVYLGRLGQKDPFGKRERHASYKKAIVTMTEDFIFPPESTAATKLPTAPKRGRTGKNNAADNKKEEKNKAAGSENTVASGNTSKTIKDLKDSKDSEEKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZJ7</accession>
    <name>A0AAD5XZJ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycoside hydrolase family 5 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZJ7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050295">
        <property type="term" value="F:steryl-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904462">
        <property type="term" value="P:ergosteryl 3-beta-D-glucoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018087">
        <property type="entry name" value="Glyco_hydro_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF5">
        <property type="entry name" value="ERGOSTERYL-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00659">
        <property type="entry name" value="GLYCOSYL_HYDROL_F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="780"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="5">
        <location>
            <begin position="90"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="6">
        <location>
            <begin position="671"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3228380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="808" mass="91887" checksum="6C8829EE2A7511FF" modified="2024-05-29" version="1">MVEQVIEDPHHDFSSEGWKKRDQNEFIKTRAQHWSGKLHTKKNQFVDNYGRVLHLRGVNLCGNSKLPVTDNGFFNHKNVSFINRPFPLNKADEHFSRLRAWGLTFVRLLVPWEALEHDGPGIYDEKFIDYLIKILEKAKEYGIQAFIDPHQDTWSRFSGGSGAPGWCFEVCGMDLTKFKECGAAHIHELIPGESEESNIALWATNYTKLASATMFTLFFAGNTFAPESRYNGQTLQDFLQSSFIKCYMHLAKRLMHLDSVVGFEVLNEPHAGYIGLPRISQHFDQNSNLNLGQSPSALQSFALGEGMTQECEFWVKSWPRPSRRSGTCIINQEKATVWLNKECIWKKHGVWGLNENGFPVAFKDDYFCKHPATSKPVDFMQDFYMPFIKSYASAIRSVDSSLYIFFEPIPNEYPPVVSKEMDDENYVYAPHWYDLKTMFTKSFDGFITHDVQGLSKGTKNILTATYLGLGGANENYKYQISNIVKIGIKNVGMKPLLIGECGCPMDINDRQAFQTGDYSHHNNFLDAVINAMEANFVNFTLWNYNPDNDNTHGDHWNGEDFSIYSPKPSRSIEKKVKAKSNLNTPNELKRNKLSLEALRTPLIIPQQILSDTARLSGMSTNPTTSNHSGQVSLSPVTPMTPFDITSAYFNMEGDRDHHHHIGGRALDAIIRVYAAKIAGDPLLMKFDLQTLSFKLEFATKVDSDFDRHPKTYISEIFIPNYHYGGVKGVQILVSDGEFCYDREKQTLYWNYDPNYMGIVKNNSVIHSMKIYVPELEKKDVWGWLAGIGIAVGLVAVGFALAKLTFDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZV2</accession>
    <name>A0AAD5XZV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Serine/threonine-protein kinase 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">STK25_1</name>
        <name evidence="13" type="ORF">HK099_000973</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTAG/PCC1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZV2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06609">
        <property type="entry name" value="STKc_MST3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000022">
        <property type="entry name" value="Serine/threonine-protein kinase 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015419">
        <property type="entry name" value="CTAG/Pcc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09341">
        <property type="entry name" value="Pcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="545" mass="61201" checksum="F44F89A284C4178E" modified="2024-05-29" version="1">MNCSNIDPESIFDKQIIDLEAAEDEIEDIQREISILSQLDSDYITKYYGSYLQGSKLWIVMEFCQVILKGGSCLDLMINGSGFEEVYISIILREVLKGIDYLHCEKKLHRDIKAANILLSSDGSVKLADFGVSGQLTETCPQKITFVGTPFWMSPEVIQQSGYDDKADIWSLGITSIELATGSPPYSDLHPLRVLFLIPKNDPPTLTGNYSKNFVDFVSLCLQKNPSLRPTAKELLKHKFIKQHAKKPTSHLVDLVEKAEKYNVTNNKSSDKSDDGKEEGPSWDFGTVRVNHKTTTVAHLLPTNDTTSKISEKVKKILEKEMLASKSEYNNGSDNSDSSYHSPNGTMRIKHDSKAIKNLTLFEDLEKDILDLNGSFNSVSFLKTSEFKYNGNLAEDLDEGKNRNESKPASNDGIMNIKNSQEDFKNEIESKCIESSFSSEINLDSRCVNKSFNFGKDKNNDIVSKVLNPTFSELQKDIYLNNKNNSVEANKSLSSLQIAFENAEQIPFPTERLAVIANKVLAVDKELKPNESKRNQKVEDNNLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZZ8</accession>
    <name>A0AAD5XZZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Minichromosome loss protein Mcl1 middle region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000588</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000114">
        <property type="protein sequence ID" value="KAJ3223868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZZ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048591">
        <property type="entry name" value="WDHD1/CFT4_hel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20946">
        <property type="entry name" value="Ctf4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDHD1 first WD40" evidence="8">
        <location>
            <begin position="30"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="6">
        <location>
            <begin position="341"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 helical bundle" evidence="7">
        <location>
            <begin position="606"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="937" mass="105574" checksum="7E8D882C2718B64E" modified="2024-05-29" version="1">MRIYVFEADLIDKDKEDFNLIGTLQYHLGASTSITTKGNLIASTSEDNEACTFKLNNNVLVNDKTLIRAKCPVNFLSFDTKGHYCALAMGDGAIKLVNLSDLIQVTNLKGHRKAVKCVCYDPKSDYIASTDAEGSLRIWDVVDLHDTKCVKIIDSFLNPTEKDSENLVRLSWNPSGTYLAVPISNREIAIIEHETWEIIAKIGPHTNADNQGHINFSLNFMNNTDAEEFVDQFTTVEERYLKIAPLHSDSNTNQNGLDVLFDDDDFSDKESDVKKNFISNNKANQQFSAFEDVDNVGQKDKLTEKYLSNTYSISEDEEEKLENSDYEKDISNSNKCRNGQTVNTYSKFSSDQLGKSGIIFACQSSSTHPSTIFFRPIENWSSQNEWMIQFGTDSKEEPTGVALTKTYIVVSTSMNYLRFFSFGGLQLGLLCLQGSAVSMVGCDDYLLVVYHREEQNMGFLLFDNSRKCILKDALPISSTSKLIWIGFSEEGIPMTYDSVGILRGLIRNSESISNSYWLPFLDTRESSKKKKEFYWPVGVIAENFMTVICRVVINFIIFLKIVFEIGYSRPSTTSCTNAYGTAYSSTISQHEYNRQFRGTVGLLLLSQDELLKKEAHGIDTEAKSKFFKIKKELDKIALTLEVSTCKAKKSQLAIDICSILHSETSIDGAIKLALHNNLPVVAEKMSVIKELVDNSKLLQQESLVEEGVLQSQPSVEVITASTQETSVYLNSNKEITQNANFQEPNFEKKKQDVEHDHDTLINGAGGKSEEEKNFIRRKLEEKNNALKTHKVNRIENGSTKYVNPFALNKFQSPATSKADPKESEEVLKKRKLLLNDEGENAKKMKKDKSLQSFFKKSTGLDKNIKSIAKVHAVEVSRQNLNNENTYNENLLNLKKNNPLEVEDDTEAKISTTHTNTDLTANKKSSSFSKLSTFKFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y045</accession>
    <name>A0AAD5Y045_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional activator spt7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SPT7</name>
        <name evidence="6" type="ORF">HK099_004683</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000338">
        <property type="protein sequence ID" value="KAJ3219464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y045"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037782">
        <property type="entry name" value="Spt7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="440"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="533"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1151"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1100"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="546"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1176"/>
            <end position="1188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1226" mass="142791" checksum="03A0B0D9288C3337" modified="2024-05-29" version="1">MSISEVKWMFQELKFRRSEKLRWWIIRKNFLDSTASVNSIYPSPLLYKRFVKEFTTLNIVEKKKLNVWLNDRPFNHLNVLVRPPILIPRPETEEITAYIANEVKNVYLNTESIVNDEMRVLECCTGSGCISLSLFHELKKVIKKLKVYAFDKNLSAVKLANLNKRNLICSKEKDDLTFFQLDMFNYLEYLKINGRTDLKFNLIIANPPYITKEDYLKLEDDVKLWEDKDALFDYTDTVNYKEIQEHLANCLEYGVWRSYLTNQEYLTVINNSKPSDLLESKIRIMLFENLYESKCFLKFKIFIREKNFFSPSKNQFQLNSSFDSKNIHNTSVSETDLDPLLIPIDDTYSLLEPLVEAEKTKLEDLFESDNENDNLLITSAPIPSTRLKYLQEYLTKSTGQTVNKFKSVVEELNPNLNKWTPQGQEEFFDLCEKVLSGLKNYKPHSLSFLTKVKKTEVKDYFDIIKRPMDLGLISKNLKNRLYKDKKDFQADLDLIWSNCMTYNQHPENPVRLAGLAMRKRSNELLRMIPDGFKVKDEDSDSDDDTQEKTSRRESSRRDSQDSTFRSPFPEDLVKEDSVEIKLEKDTVMEDVAPEIDEQFDKVEDNEFFLQEVKNNDLTLNFRQKLQKARSQQFSKPFPERKAIQAMPEDFKKFAVGEKEYLKRLDLRRKVLIDKDGNFVNLENSEENQTMITEENNVSNLMNVEESNCEKGKGMKDVTEEVLELNLEEFFLPELFNFSLPTLHGNGEGKFFFGKVELDIEDLFSYETPKKLLDSLPSLSDYPEFLPDRSSKLNYIIMSNLHHLRKVKEYNARISARETNFHESWLGIPAEPEIYKPDYQKFRPERPDLNDNSAGEIFSQNLSVLVSHVGFDAISECAMSTLLDVGTKYIQNLGKTFNLYKEKLNFFINSFNLSSEDILLLVLKQNGLYDLSKLEYYIRADCLLYGQKLKDLAMKLSSAYLDNWSPTDDEDLKLEDYSEQVISGSLFEELDIDILGMKDMGLDFLSIPTELWNKKAEKPIKGRLKRKIVEVQNDPILESTVNKLTPPEKWPEIDPSQQIGLLKNLYQKIVSNNELAKEDEFKTLTMAKRNLIKVATQGRKRALQKEEIEQAKKKKRFIIEQQKLLQQQEAKELLLQQQQLQREQLLLQPPNMRGFAPNGSTDSLLFSNPVPAGTSAKDAKALEKELRKAENRKKKEQREEKKKLKLLAKLKNSNQNNDGGTGGISQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y053</accession>
    <name>A0AAD5Y053_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PUA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_003674</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000242">
        <property type="protein sequence ID" value="KAJ3221243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y053"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21157">
        <property type="entry name" value="PUA_G5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000018">
        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF3">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="463"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="597" mass="67022" checksum="C63C2725613771D8" modified="2024-05-29" version="1" fragment="single">PFELPVKLLEKNEDVKLFTVEDNFIKILHESPYFLEDPPKKPDVFRYTDKYKKKSNESKSLTKTIKYGAIVDLSFFPDELHQINNSSKKKFTSKLVKKDFDIKTLNLLASEEDKEKKEHSDVEDEEEEENIEDEDEMEEDNDYLIDYYDDDFEADDGGDNDLSLQMKQIKPKKENVIVIKLGSSSICDSKLHIRLSTLSLLVETIKDLREKGNRVVLVSSGAVAVGLRRMHLKKRPKHLSQVQALAAIGQGRLMALYDELFGQFDIPIAQILLTRDNISERSQYLNACNTFKELLDMSIVPIVNENDSVCNAEIRFGDNDTLSAIVAGMVNANHLFLLTDVPCLYTDNPNTNPDAKPVRYVDDLPKLRGEIDVSGAASSNVGTGGMVTKLIAADLATAVGCATVILISTAPEQIGIFINEFTEHNKTNSTENFIPSVGTLFAPKSNPLQDRKWWILNGLASYGKIFLDAGAVSALKNKNSLFATGVIKVQGNFTSNQKVNFYTVVRKDNKTKEDFDEFCDIDDINSALFQTVEIGSGLVNYNSTEVNTIKGLRSHLFVEKLGYIDSECICHRDNMVITKNVEVFSIVNFKKNDKKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0F0</accession>
    <name>A0AAD5Y0F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein PTHB1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BBS9</name>
        <name evidence="3" type="ORF">HK099_008033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000084">
        <property type="protein sequence ID" value="KAJ3224715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0F0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034464">
        <property type="term" value="C:BBSome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028073">
        <property type="entry name" value="PHTB1_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026511">
        <property type="entry name" value="PTHB1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20991">
        <property type="entry name" value="PARATHYROID HORMONE-RESPONSIVE B1 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20991:SF0">
        <property type="entry name" value="PROTEIN PTHB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14727">
        <property type="entry name" value="PHTB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTHB1 N-terminal" evidence="2">
        <location>
            <begin position="40"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1144"/>
            <end position="1153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1153" mass="133207" checksum="BAAD70B46E1919D8" modified="2024-05-29" version="1">MKKVYEISDKVTKFHISNDHLFTANRSSVFSFSLKNVSNSSQFSTSLNNDILQITAGQFDLNSDISSLAILTKDSLSFFSFDQCKFTIINELNILNAFDMILVEKNFDNKPTAIGSKSSISLICIQCFTGIFTLIENYAISFTFNLYNSIYPNPFCYVSEVDSFLFQSNERAIELFSFDSLKLEHVKPLQSLVLDDEITLIFSSVKLLSNNTSEAFLVLTGSYLYFLEVKSMEFLCQISLSSIPLCGYINTLYEQQSGEKILDTLLIGCCDRTIKIYKELILSWSIDLDYVPLQISTATFDGNPKMLAVLLDNGNFSISCLKIQTDDELLYFKELEEFEIQKLFSDHNDVDIEEPKAKTVKDNVADLSNKNNERGKTHLEETKCKTLGNQSASKLVNKSNLLKLNESIAALENEIHLKEKQIESNDYQDFRNIVKFKHEMYVYKDEEVKLEDFFITELKICTFIELDDQLLKDVCIYLEAPPLIEIEKTEYQINLLKSKETKDFFTKIFIKKSSPIPYSNEVKVIWIWKDSLKVIELPLWTFGVFVPIKNDLDFKFQILLQTNGKDKSFEDIYCDCPNFVNFHENVDKNLIFKFFNKVDNFVKIVNLGGESCNYSIETDDLSLLWIFIKDFSFRLHSLFEKKENNSAEAFHIFFFDEIPNEEIFNYIKEYERTCITLEEIVINSSESLSYFNYFQSDFEVTSQEKISVFEEEKEHLDNNFVHETNSEGIKDDVELAELEEAFKKEMISEASSIEQEDLKLTNLSKFETILKNRLNNLNNLQTIHSKLLELKIAVFNFLRLYVELLRIKSIISKSNYEYIVRRIFNFSLHFTEEEDEMSIFKLENIKNFFTIFFNNLFLHYFNSDDISDDNNDEKEYLDILASKKKKNFLHFEMKFLLLITIITTLSFVQSDICRDCNVEFAGCIDQIKDDASFKSCLCGSGKNNATFAQKCADNGFFGACSNNHVNKLLYNIQSRAGLDGDTLPSLCTKPINSNVQFAISTWEDKNGRLNPPATHNSNYASQPSSVFVNPNSTPQTQHHYEQNAYNNNYNTNYQQPYQNNHQQFTQQPYDNSSYSQNFSQQPYSNSNYSSTYPSTNLEQRGNNYNNNSNYSAPYSNSNTFVSQNPSNTNANLPPYESNIPLNDISPNSKISKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0H1</accession>
    <name>A0AAD5Y0H1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_003031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000205">
        <property type="protein sequence ID" value="KAJ3221847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0H1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="136" mass="14968" checksum="693D14DA9F41AA66" modified="2024-05-29" version="1">MSTGFTAFIVVLTLVSLLSMLGLIYFFKKRNKSDKLDGSEALNFNLNHHKLGDGSYHPSLTSGFLVNSGAVGYNDRIHNKLKYNNNSTSAPRSEGYSYSESSFGAGSSIVNTPYPYQNYPLGLGYSDDIKKLNVNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y191</accession>
    <name>A0AAD5Y191_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001398</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000139">
        <property type="protein sequence ID" value="KAJ3223210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y191"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061459">
        <property type="term" value="F:L-arginine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005290">
        <property type="term" value="F:L-histidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015194">
        <property type="term" value="F:L-serine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF678">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="47"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="1"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="438" mass="48223" checksum="534D5A86765C0857" modified="2024-05-29" version="1">MSRVGLGLGSLLVLLAATMSAFGLKLLSKSAILLNNRNTSFYEISKVTYANAAVVLDAAVAIKCFGVSISYLVVIGDLMPEITKTVFPSAVDSLYSDKNFWITIGILLISPISFFKKLDSLKYTSTLALVAVFYLVSIVVGFALIWPEGMPKSGWIKFENIVWFRFGNGMEVAKLGPVFVFAFTCHQNIFAVHNELYKNTKKRMAHVINLSISSAFVIYQTIGILGYLSYGESLNSNIITMYPKNSFVTFGQFAITILVLLSFPLQCHPCRQSLDKVLDGIAILYSGDAESGDNTIKKGEISPLKFNLMTLSILVFAYIVAISVKDLSSVSATGSTTICYILPGILFNKMCWIIEKEPIQVQSESAALLQDDQSQNQQHSQEVVSCNANEFHQNFGFKIGNVGNKVERYFGLLLSLFGFFFMILSVSVQLFAGQSVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1Q1</accession>
    <name>A0AAD5Y1Q1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1Q1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="989" mass="111611" checksum="6035E09C1FD8B86A" modified="2024-05-29" version="1">MIPTSIDLSTGSARNFLRRVPLSLTVNGIGDVNNFIIPNKIIREENGNDDTTDTGSYTTKLGESMIAITDIISSNSNDIEHDIVFNEVVQRYLSRSYNHFKTSLTSRIADGAQDQAHTAVLEAVQSMANGINTLHQQVCKGSITRRRSLLKRNTCTAKVVKPIEQVFKDNGIDIGSQGEITEKMVNDLFRSESLNLEEAFEVNDDKKLSNTLKKIFRINFFKVLEKRNADNPPSDDIQYTYYKADPDINPDIDLLDVLDVSKEIGLEVANDGSIIEKADINIKGIIDGKIAELEKIIEYAENIKYTDYKKYQKKLAKLQKVLESKGAHPELVKLYNTFVNIISLQFIIDFAVDKFETFLYGNPINTDKLSPPTKPLGIDPTAPNEKLVDMDNKLIEDGKGTVGDNNIQNESPLQDKLGKWHRAWKPIIKNLQIKAKDNNVADEKLTDFMNIINPIGDNKNTESFRDVFGLDKVSDLNIDEVTLEKLQAFKEKIRFDKDDIESYMLNVDIYNNIAYRLHMNGKSINSKLLRFPIINDPISVQEIKILETELGINLLASPEEIGQYAIDKIIAKKDVDRKLLKKYIGLKTLEINRTPKEERNLVEISKIELLSVSADMYIIDIRPLDHVISILTQDSLVLLNKAGLKNVLPNLGKDSDRTDTNNIIDGQELLAGEPNHDVAIHKLGELMVDYVEKNPDNKISGRLLSNQFKIHRLLTTELSTQLDETGEIDKDTEFTHNTLGSRIDRMLKANIKLQDSGEKDDPTFPSSSTSAVSKSIGINPRFNIAKKVDKKLSNKLGRLGKYGKIGVAIGRFIKSGSISTKSNKEPKSKSTAGHLSSKAILTIKKKMNLLNIKNPIITMDTDIKIDPDLRYPKPIHTMFGDELAKKFNNIVYNDNSYVFFHHSSDDSYALISVIDQGNSMEDFILYECNAQRKSAYSSTYYMGTSGTLILFYDSLEDFLTMMEPPRVFEYWNGRGVIVAQNTIFKYNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1X8</accession>
    <name>A0AAD5Y1X8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">uridine/cytidine kinase</fullName>
            <ecNumber evidence="3">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HK099_006702</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000006">
        <property type="protein sequence ID" value="KAJ3228077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000010">
        <property type="entry name" value="Uridine-cytidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002859">
        <property type="entry name" value="PKD/REJ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02010">
        <property type="entry name" value="REJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042143066" description="uridine/cytidine kinase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="2153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1610"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1827"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="domain" description="PKD/REJ-like" evidence="12">
        <location>
            <begin position="852"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="11">
        <location>
            <begin position="1767"/>
            <end position="1900"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="13">
        <location>
            <begin position="1946"/>
            <end position="2148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="542"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="552"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3228077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2153" mass="234088" checksum="4F2A8122DE4BF32F" modified="2024-05-29" version="1">MSKTKVLRLIALIVSTSSVFTHTITLPHYSPTETTKNIEDDVYSTAEFVLHKRNDIPVSFLEPNEYILQNRALTQSYEIYDTSATLEHKSDSSINFGPVTATITQNVATTLIWFDESTSLDESAEYVYTSIDAESENTSAKSETTMIWIPIDEKATTVYIENSLSEYTIETHTIEPSTTQRDRDFIISSEIPVATSITWIDDMPSSTRPIIAGSETSVYYESTKTTEVFESTVQYTAKATSYHNFFTELDSSTNAQTSTSVPISTTTYPVPVSTTAVPDCTFSEKDCNGNCPGTAKFLGINGGGRDACGVCGGNGTVGCLQFYGIEPKVVPHKTGQNVTIIGGGFLPVGNTSIAVTLDGNLIDQSQLFVLNDNILIYQVGAEKFSSTDLLSFNLQISKQYQISVSKNIFMYDPEISTLNEKPYFNIESLLTDKENVKFLINANNLLKLTSSQVAFFNPTCVFKLNDLSWQSSAVYVTGEGKFNSSYSCGDLPTFEVGGLLHVNLLYSKPAFATPFHPDVNNFTRPELYAWSSSRYTTVYTPPPNILDTGNSTENGNTTIPTNTTNTTNTTISTQYNGNGVYFSNTGASIKVMFDSTIKLINSTIFTESNGLTLVPLAEPILCSQVFDTSYPNNAGYLQSSNSLDNRDCIVTLLPTSITLTFSGSFTSKNLSAIKPGDYLKLLSNTVTRSLEPYSLPYTSRWIQVNYPIIIPLPEVIINSPHVIGGCVDYSLDFSSVSGASGRPWKLVSINFEIITGNVTLEQKAQIQSDLDAGASSVTFGSTQISIPKEVLPEGAYSFSATFENFLSGKNTETVSVTKFDAKEVPFVIITSDNGYGALPVSSSNYLRASATTISACNISDTVEFNWISADEKLNLSNPSRATQVFAPYSFEAETTYEFNLQAKYSQFNKWYNYTISLTTVKSLLTVSAGPSRSVGTSSELILSAMIIDSSKKDTDYSNLACTWKCTDTNFGLPCVNQNQEVITFDDSCKGVNKTGEFPEGNYQIDVSVVKGNDSTPTNGSPSFLTILAGNPPLINIFASELNPSSFSPSFNLRANVDYSTISSSTNLVYTWTSESSCNSEAYSSVPLENGVTTATDPGNPALIFIPGKLKSGTEYCFKVQVHDTLSKSSGSSSIIITTKEAPSGGICKINSQAPTLEYSDKVKIQCAGWTTDAKSNPIGYLFYIKNKDVPNSDWSVIRGYSPSSFFSNVYPAGNFQIKVKIIDSAFSETYSEIMEFEVIKPSIEKRSLQKRASAYQNSLNFIEDAAKDFGSTKNAADAVIALNTVKSSLPGDIASDAEAVELQLSILEFMATVVTSEEWFLDATNESPTAADILLSAVGTNWKFKETSCLKLFGLTEKTVNLINKNVADSCYDSSTATKFAKVLDAVISSLNANSAFSSTIANKFLLVVSVINKCQFNVQKCGKSDFKYSGTSVNYSLGNSNPTSPAVYGNIQVASLSATQCYQYTYSEVTSKGLLTSEATSNLVATDKNILSFSLFDETTGEKILSPNMTGTILVAKDFEERYVNKPKYAAAVATIEFLSTDSVIATNGTTILAANSGVVKFSSLKAGSFLAVVKEVPVTETATPSATPTVTTTATATPTLIPGDSTSAAAIGGGVGGGIVGLGLIACIALIVKRKKSKKKINGATGNDAAIAASFGAAGANVAGKDNDAAIIASYGGQTKEPQVVIDINDPPAPVPDSQQDFDALKQVPEPNNTDAIVNASQVMLPNDQSSDYIAPVAPQNYERVASYAEATQRSDNQNHPDNLHDASMEESANAMKGNHDFDHPSCFDYECLFQTLSDLKTGNRVNVPIYDFVTHSRLQNKSRVVYGANVIIFEGIFALFDEKVRNQMDLMIYVDTDADIRLARRLKRDIAVKPSYDQYIHATMKYADIIIPRGLDNTAAIDVCIKHVLRQLNLKGMMLLRNELATSLIDSTKPLPENFFLVKSSNQLKFIHTQIRDVNVSRPDFIFYSDRLSRLVIEKALGLLEYEEKDFITPLNLTYKGTQQTKKIAGISIVRAGACMEIALRSVVNNIRIGKILIQTDARTGEPALHYFKLPEFQNHSIMLCDATLGTGAAALMAIRVLLEHSIKEEMIYFCCLIAAPQGVHTIANAFPKVKIISSALDQGLNDHFHILPGIGNFGDRYFGTEDDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1Z1</accession>
    <name>A0AAD5Y1Z1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1Z1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="318" mass="37056" checksum="86C75E1CED466DF2" modified="2024-05-29" version="1">MKFDAHKKKASQKWKLKHAVGDSNKAKNNEKEIDVTESEISLEVDNDHKFRKRQLTSNEYRYKEDSKEDILAKEADIDVETEDLLAQLKENQLNADFDHSQFFQFKEEKIWNEREVKESTGKFNDALQINFQHLNNLMKLLPIETRCGLEKWEIEDFCKADNVKQNTMTNLVEDDKKNINQTNSRINLLKMESTISTGLKNLNEEKCIDGSNKKYSKIRQSEEKHAADSVKVQNSEISNQKVDLFQKKKETELVTNSSTEKEKQECLNNVDKEIVYRKGLDTSNISNNCGKDSHQDKFTKPDDLDVNKLEEWLDDILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2A2</accession>
    <name>A0AAD5Y2A2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RPS4X</name>
        <name evidence="9" type="ORF">HK099_000186</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000103">
        <property type="protein sequence ID" value="KAJ3224136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2A2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06087">
        <property type="entry name" value="KOW_RPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000005">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.740:FF:000001">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00485">
        <property type="entry name" value="Ribosomal_eS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_eS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032277">
        <property type="entry name" value="Ribosomal_eS4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013845">
        <property type="entry name" value="Ribosomal_eS4_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038237">
        <property type="entry name" value="Ribosomal_eS4_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041982">
        <property type="entry name" value="Ribosomal_eS4_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013843">
        <property type="entry name" value="Ribosomal_eS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16121">
        <property type="entry name" value="40S_S4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08071">
        <property type="entry name" value="RS4NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002116">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="8">
        <location>
            <begin position="34"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="250" mass="28502" checksum="0F9C47931B5D86D9" modified="2024-05-29" version="1">MYRLNAPKHWMLDKLTGTWAPRPSPGPHKLRESLPLIIFLRNRLKYALTGKETTSIMMQRLVKVDGKVRTDVTYPAGFMDVITIEKTNENFRLIYDTKGRFIIHRITAEEAKYKLCKVKKVQLGAKGIPFAVTHDGRTLRYPDPLIKVNDTVKVDLETGKATDFIKFDTGNLVYITGGHSMGRIGTITHREKHPGGFDIVHVKDALDRTFATRIANIFVIGQGVKPWISTPKGKGIKLTLEQERDRRREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2B3</accession>
    <name>A0AAD5Y2B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Elongation factor-like 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ribosome assembly protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">EFTUD1</name>
        <name evidence="15" type="ORF">HK099_007079</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000066">
        <property type="protein sequence ID" value="KAJ3225253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2B3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16268">
        <property type="entry name" value="EF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000006">
        <property type="entry name" value="Elongation factor like GTPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000746">
        <property type="entry name" value="Ribosome assembly protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056752">
        <property type="entry name" value="EFL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF3">
        <property type="entry name" value="ELONGATION FACTOR-LIKE GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25118">
        <property type="entry name" value="EFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="947"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="domain" description="Tr-type G" evidence="14">
        <location>
            <begin position="16"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="437"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00068031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00081809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3225253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1092" mass="123151" checksum="6E9ADF6E863DCFC0" modified="2024-05-29" version="1">MGVDLEKIKNLQKNSKSIRNICILAHVDHGKTTLSDSLLASNGIISSKLSGKVRYLDSREDEQQRGITMKSSGISLYFKVLRNEMDENTKKIELKESDFLINLIDSPGHVDFASEVSTASRLSDGGLVLVDAVEGVCTQTHTVLRQAWSENVKPVLVINKVDRLINELKMSAVEAYEHLKLILEQVNAITGTMFSQKSFEDDNKKYEENINDASALEDWNLDLQDDSNLYFSPEVGNVIFASAIDGWAFRIEQFAKLYASKLKIKEQLLKKALWGDYYLDTKAKRVVGKNGLKGRPLKPLFVQFVLENIWAVYDAVCGSNDKQKIDKIVTTLNLKINARDLKSKDSKALLKEIMTQWVPLSNAILLTVIEQLPSPVDAQPIRMPQILKKSENQNYADLTSKLQNGIYSCNSAISSPSVAYISKIFSVPKKELPSQKLKKALQTAEEMKEKREKYLAALKQKDMEVNAEPVKTSKIISEVEKNNEGKMEDSEEEVLIGFARIFSGTIRNGDKLFLLGPKYSPEKKNYLAEIIVEDLYLLMGRELEILDEVPAGNVFGINFTGAENLVLKTATISSTLDCPNFGSLNVAAAPIVRVALEPADPSQMQKLVEGLKLLNQADPCVEIIIQETGEHVIVTAGELHLERCLKDLRERFAKMEIHVSEAIVPFRETITNVPSVLSPNLQLFISNNFQGLDRIENKDILSASLSLEEKFPTGTVILKTANKLCTLRVRALPLPKSLANFLYEKEKIIKAFIEERESPIAIKDLDLFFDEFNKTFFQNIKIRWGRYFEEADLKKVFENIWAFGPKQCGQNLLVNMVDGYEKKTWMSSMRGQKLKQQIEGEIISEEIESTANNNKIYGIKDFQGSIASGFQMATLNGPLCNEPMYGLCILLEDCTFHITEDSDALKISLLSGQIITTMREACKLAFLQWSPRLMTAMYSCELQAPCIIFTLIISINFGIADVLGKVYAVLAKRKGRILSEEMKDGTPYFSIKSLLPVVESFGFAEEFFVKEIRKRTSGAASPQLIFQGFEILDIDPFWVPTTELELEDLGEKSDKENFARKYLNFVRKRKGMFIETDKVVEFAEKQKTLKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3E0</accession>
    <name>A0AAD5Y3E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000036">
        <property type="protein sequence ID" value="KAJ3226432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056252">
        <property type="entry name" value="Alfy-like_Arm-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051944">
        <property type="entry name" value="BEACH_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46108:SF4">
        <property type="entry name" value="BLUE CHEESE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23295">
        <property type="entry name" value="Arm_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14844">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="4">
        <location>
            <begin position="2234"/>
            <end position="2366"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="3">
        <location>
            <begin position="2395"/>
            <end position="2454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2454" mass="280747" checksum="1AC6EB8D8C5F1B0E" modified="2024-05-29" version="1">MDWINKKFGFEQSTTAAVKSPNIATKPQPQSNQHVEKTALLNGNGTLSTEDIEKQKNRLKATKELVNKLSQVISIRNENVSSKQCVEEIKKLAVIVWKRFSAAVLHQIDRQSHDAILIKILHLFNQYPPKQSHKNSTSDELCETITTILSNIAKRQKNLISIFDLMDIICVRQQNKKNLFQNQDHTWRVIALEVLHIVLNKADLKEADWQIFDNKNYLKLLIDTLADFVDLKETQHSKYYYRAIVDILTVSSQVTGKLSEEFLTHRGYDCITSYLGCCLPSGAAESFNFVINCFEQLLLAGNSVIVPKIPEQPFQLKTANFTNLKSENSIKNPEALVVFIDIFKSNYYKLSKTRGSFDPLYSPDKLKFKLLQSALLSLILKLFLQSIANYFIMESFNILFTLIENFAKFEIDLQQQVLLLCEHVLLSISYVPVKELVFLLPYIQCTNSDTSETSLAVCQMFFNVLKSSSKCYSTVFREVGLLSALTCCTHDLVIPCSNEICANPFVFHNKKLILKTISIMTCEDLENANAFRKISNGVAFDLLKFPEHRNVSFEIIKSMINESLSAGSKELPEFSRLIEVLQSIPRDHIDLKLEVLLYIMDTMNLSLQVRDAFRESGGFVALISILLALENIFCNKENISNKKSSVTEDLHLIRSMMKSIFSILIIAIKDNESNRRFLVEEVGINTIGDALLLTGIMSTNHCDIAFGGLLGLSLEDTFSLNFFKEDHLPKNVSPTKLELIAKTAITSSEQNPTIKTPGFLLCSFNLLPHANSAGLFQNYTLQIFLALSKINKNNQLQMNECGILEILINWIFEKDSWIYKSKDSIFIDYQVQTVKLLSKILIEMGISDSELRVLFKKFQINQSTLGDELHLEVMELILHGLKSNKTPCYLELNSANQSNGCLWFEDFGKPFPPANGYTFLSWVKVEKFDPVHNIPIIRIVDNEEKTRLLFTVENKLSRKLRIQTFKTNVTIDTFQFEENRWYHCAIVHQKPRITASYVDVYINGELIQHVKCPYLGHPGSAGRIRTFFGFSSEQKSTETYSSVLHLGPTYLMEETLLNCKDVNIIYHIGFDYTSNFQGNLSKYLSNEAMQLILCDLPTKKSMREKASQLNLFSSASPLKKVVLSSIILEEKILIALIPKNYLGVISKLYYGEKSSILLNTAKFSAVKAVLNSSPPKINETSQVLNMAYLKGEALVICPQKMVDGIWKIGGMATTEALLMSCKVFAECLRCNWRNVEETENNGFYELLGHLLRKKEKLLSTKIMDVLLEVVGKYHDNADSAVIFNLAAYRYLFMEFELWQSSYELQKYHISQFLVFAVQSVRSELNMKKLHLKSSDCLTIAPFAMKMQLFSDSLMQDAMNLLKILVQGNFTAEMVRHICTFLVATLPKSENGDAFKLNIGRRTLLTSSVITPVSETVNFPKIIFNSKEEEIPNYHVALRNYLLNMILEVLCESKQSNVKTKVFLSAITTKWVLLFFQKNLHPYTVVLATKVLARLMYNQETVYIDRFKEGFVVLSDLLTSHCYNYEIFHSLLSIFCGTDISLVPYNTSGDVATLMALYKLSDSSKKKTLCSEVAFVIVELIKAIVNSLIFVTEKFTQTLGDSEDRDDFNQKKVQKALEFPNAILEFFVEASRMSEEVREAITNSGIYDRLITIFFTTMNSSKVINPEDECKELAELLETDNIPSYKFTQGSFKYSDFKFSSDFTQEKIETWKVVDRDNEYKNSSYNGLRETIGKLLISACIESIFISAKPLRALDLMMKGNPIASIDSQVDLHCYLLLHLMYQIQITIKRQRSLLIDVKSISNLAKVSALLIDRLCQGLFSGGHIVIMDFVLSVLEFTQQEMDKAQKFDQSLTLFYKQSNRLLLLCLGHFSTLQKISNNHTLIDVLQKMVHYQKIIFHIQNNDNEFYKCLIHHIYGFLVNTQHENTRMASLAIWKLLILQRPTNLKTILRSQKGVEFKELIEGFGGILEMEQRSFVKWIESRKEELNSLFYENATKVWDSFSLNEMKTGKEGYKLLLNKRFLKIKKIWTADIQNMESKRALTQKENEKSMRKFFDDKWKAISNDLISERSLWGPKVELNVKWKLDFTEGRSRMRKKMVRNNTSNTYLSKLDKIHNSIGNLVTDAENSPYSSAIDPLSSSLNVSTGKFRSLSDSSATIKKSRLSNSPALRSRVISDADSIVLKDLPSENGEELSFVEDNISEDQTSTDDEANLEDEDEYEKVEMVEQESKITRLIDPGDSILEGFNLARIVGLDVFGMKYLVFSKIFQRVYCFFAEKPSMSLTPILKGQMERNEYNAFLSDNRQLLEKKDNDERYVVRKWNYQETSDLHFRLFLLRNVAAEIFLADGRSLFLSFSSTKIRDLVYNKLLSKATLTSSANTEKFSGTSGTEGLGTKLRQNILGVSPLQELTQKWIVRDISNFEYLMRLNSLAGRSYNDLTQYPVFPWIIKDYESEEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3N2</accession>
    <name>A0AAD5Y3N2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphate system positive regulatory protein pho81</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PHO81_2</name>
        <name evidence="7" type="ORF">HK099_003505</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000023">
        <property type="protein sequence ID" value="KAJ3227052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3N2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="54"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="94"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="135"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="175"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="6">
        <location>
            <begin position="950"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="555"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="871"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="330"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="568"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="883"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1018" mass="114592" checksum="78CF74DDF7342D23" modified="2024-05-29" version="1">MKPRLVTQISSAHVISTLTIHNDLLFTGGIDGSIDSFDLLVGRFAHFEPVLFAMQAHSSSITSLVASNGVLFSASEDSLIKCWNVNTGNLISVIESHIGAVQVLNICPRGFLISGGEDKNIHVFDIKTGKRQMLFEGHTDTIMALASTDTLSFSAGYDNTIKIFSLETAENLYTLSSHTDCIFTLYVTEKYLFSGSSDGTIKVYDYLNGGEMLYDLVGHGGHTVVSLFYSNDNVLYSAGDDKSIVQWSTDLEDGVPVHSLLGHKDLISSLCANQGLLYSAESDFIYVWDIDATNDALSFDSPSLLENLSIDIPSFNSKLSDVSNKILDPADEIRALKEQLSRAQELLEKQNKHKLKLRSEVSSLRTELSMVKSDLAISISKHERLPVLIEELNSTKDLLNQYKSELQSCQSAHAIAVSGFLQNFDTQWMAIESDLASTQRWLNEMDTIAKFNHDLANYMPLNPRKSKDLWERDSDWDSDIEEEIQSKNNWWRSNDTSSLSNANSTEPTFIPSSEQPLRINTEEFVVTKGDILNLSSATVELAPLNITEHPLSNIPSEELLHGDDDNTNLDSGTESSGSISRDLDIFDSDLPVPYLVPFPNADEEDSGEPITPVEEAVENHSIQLDLSAKPLVAAQLLSQKNLQPKRKTIKVPSNMVYTTSLNQHVTNKAMGWLQPFKSFVNTLVGDEEDQVYAYNTNHSKPRKHVETLFEGDAYHTVEQVKPIKMEINENIEWTGGVKINKRNKSVKHYNIVSENSLSNDDINYKKVPKIKSDFYDQESFDKIEFKGKARINSKTNSISSSSYLENSNIEGEWTGKAKVVFNAFLPDDSKVFTEIFNVQKQDKSSDANAIKKKHMKKYGKLRHSDSALDLNYSSSSEEEEEFQGNNSKTNKIQSDNNHNSQSQDSLIRFATAIENVLDNVIERPIDTICSFIGNKITNYSSSSRKKLRDIKFGKYIQSQQEEWAGAQYLNYKQLKKVFNSKPENEMNLIKTTFFYKLERELEKVNAFYLQKELQFKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y416</accession>
    <name>A0AAD5Y416_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_008310</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y416"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03506">
        <property type="entry name" value="Delta6-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353:SF88">
        <property type="entry name" value="DELTA(5) FATTY ACID DESATURASE FAT-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="FATTY ACID DESATURASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="12">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3227900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="438" mass="50486" checksum="3C8AAC173D9F36F3" modified="2024-05-29" version="1">MPSVPTFTWSQVEASNSDLSKDKLIVINDKVYSIGGDFVYWHPGGKVALSQTGRDATGAFDQFHSESVQEVLSDFYLGDIAPTERREASSFRKDIEKLQNEFQKAGLFEASKIYYFFKVLFNISLWAAAVSILHIFGHNTYGVLISASILAIFWQQCGWLAHDFLHHQVFKNRTLNNYMGIFVGNICQGFSVSWWKNKHCTHHSMPNVHLIDTDIDTMPFLAWSEHALEFFNDLTDKQAAKFLVSYQPILYFPILTLARLSWAFASIIYCITTPSTLFETSIFLFVERFSLLMHWGWYLFISFYYLSPMMAIVYIFVSQAICGFLLAIVFSINHNGMPILDTKEASKVDFYEMQVMTGRDVTSNIFNDWFTGGLNYQIEHHIWPTLPRHNFHLVTEKVQSLCKKHNVPYHSTSLVNGVNEIIQRLDKISKLAKKTKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTV6</accession>
    <name>A0AAD5TTV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trafficking protein particle complex subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TRAPPC12</name>
        <name evidence="2" type="ORF">HK099_001698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001504">
        <property type="protein sequence ID" value="KAJ3202905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTV6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581">
        <property type="entry name" value="D-ALANYL-D-ALANINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="662"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="742" mass="83921" checksum="363340843AA6CA4B" modified="2024-05-29" version="1" fragment="single">MQEEEEKIIPFSHKTLDVNDELLQKRAVGEEDHHPPIFTEKQTSQKSLNIDLSDPFFLKNSHQTSQEQNPDFIKTFQLKNKLSQSTSLIDLSTEDDNLNQQLPPLIPQLQPAQHPNIPFFDSSKFINPNYNSTNFFDNQTAISNPVNTDVISNNFTPQKMSDNQFGMFSDNHATGSADNLQKLNPSLQIGETETSLFNTNFNNGMQGIPLTSPLEPLSSVPANSSQDILQPTAYQQHPATPPNVIGNPSSLLFNSNVDPFANNHQNSVNYQIFSSNNSKAKQLIEIGNIQSSSFILDPKILALPTKKWLDVNIFSDIQRLDPIQDLIAKFFTLSERPQRKLLKFEDVQNLSEEAAFSKLFAAGSFRAAAQLVRSKIVNRSERMHPGKPDEICRLWYIRLLCLVQLKCWETAQYEMEKLGIYLEKDIDPAISVEQLELKSKNVKNPVVERPWTFESYPDIFPNRKGSMVSFELRNFHALWPSLKGNPQDSLNRLYSLVFICRKNSLNAKPQTINESINDSNFWITDSFLLWRIRELRLHLQIASCLVDLKQFKLSTQILTKVSNSVNRLTEKSIPMLTSVLQKFKIDTISAIGRCHLQSGNVAAAEVTFHSLERLLLGPDVPRIITNEKKLRVSRSSDMLSYRDPQSQANIDQKPPANFFDFPRLLLNRALLYLAIGENEIAANYFTALVTVEPSGMAVNNLAVAKLYTGDVGQAISFLESICVEKPNEAGICENLIFNLCTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU16</accession>
    <name>A0AAD5TU16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001418">
        <property type="protein sequence ID" value="KAJ3203515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU16"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052514">
        <property type="entry name" value="SAM-dependent_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203">
        <property type="entry name" value="METHYLTRANSFERASE, FKBM FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203:SF15">
        <property type="entry name" value="SLL1173 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="1">
        <location>
            <begin position="35"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="253" mass="28412" checksum="122A1A1A31BD1F4D" modified="2024-05-29" version="1">MSDTFLLNNIENLPHYKKNCLFGEQKHPDFDVVIDVGAYDGSDYTIPGYNLGYTVFSFELNPANHQLCYNKFAAAGFKEGVDFTTIEVIPGQVPKFDSSKRPHIYFIKAGVSNRNAGIKVSGVDVYGQVDPKAKGDSPIVKIDDFISDESVYVFKADTQGHEYGVFSGGLKVLNGVIKFVSLEYWPQGHRENGFNSIDTLNLMFDAGFRCMDYKREYMPITRPSEIHEFTEFIDAIPRSTDALGGWVDVLCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TU59</accession>
    <name>A0AAD5TU59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_001542</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001443">
        <property type="protein sequence ID" value="KAJ3203348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TU59"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797:SF3">
        <property type="entry name" value="CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47797">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05805)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="8">
        <location>
            <begin position="129"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3203348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="275" mass="29820" checksum="5C6B44B79DB8D907" modified="2024-05-29" version="1">MQFTLQSFKPITGYFAVGFGNSMKSAEVYVIAGRRSATGRREPQFIEEAQADFSLVPSLTKVGSEQTIITFERDMTVQSIPDVSATFKEDEKLTSMIWAVGNLGFSSDDPSNSIPIHQRDNKGQVSVNLFDKVNSPYIEGSSPRSGNLEGQGEGSSSSSTLIIMHGVFMFLAWCVFAPTGIFVARFFKDILGENWFKLHIGLMLGGGSLLSVVALIIAVVATGGIDVSDMEALGTSHVVLGLIVIIVSIAQVVSGFVIDKLFDPARNKIPWWDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUE1</accession>
    <name>A0AAD5TUE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PKA1_1</name>
        <name evidence="14" type="ORF">HK099_000769</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010001197">
        <property type="protein sequence ID" value="KAJ3205521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUE1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF153">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="132"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="387"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3205521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="441" mass="49642" checksum="1D23478C411E178F" modified="2024-05-29" version="1">MSLLKKINSSLNNKFNVNSTKNITDQKVEEAPTPPKQESNIQQQPVATNIIANKIDTTPAATQNNQNNGVVPMDTSCSRPQTPVSIPLAGSASAMEVDKEPLTTTITTTTVTQGTVAAPVVKARPKYSLTDFNVDRTLGTGSFGRVHLVRLKSASKYYAMKVLKKSEVVRMKQVEHTINEKNILEQLEFPFLISTLSTFQDCANIYFVMEFVSGGELFSYLRRCGRFPNNVARFYASEVFLAFEYLHGKDIIYRDLKPENLLIDHEGHIKITDFGFAKHVPDITWTLCGTPDYLAPEIIQSKGYGKAVDWWALGVLIYEMLAGHPPFFDEDHFKLYEKIVACKPKFPAHFDPAAKDLVKRLLTADLTKRFGNLKAGSSDIKKHKWFIGIDWQKLKALQVQAPYVPPTKGEGDTSNFDAYPEDHEPYGTICPDPYREKFKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV36</accession>
    <name>A0AAD5TV36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Cytochrome b-c1 complex subunit Rieske, mitochondrial</fullName>
            <ecNumber evidence="12">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">FES1_1</name>
        <name evidence="16" type="ORF">HK099_000314</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="12">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">The Rieske protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010001069">
        <property type="protein sequence ID" value="KAJ3207246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV36"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03470">
        <property type="entry name" value="Rieske_cytochrome_bc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit Rieske, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.270">
        <property type="entry name" value="Ubiquinol cytochrome reductase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037008">
        <property type="entry name" value="bc1_Rieske_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004192">
        <property type="entry name" value="Rieske_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02921">
        <property type="entry name" value="UCR_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81502">
        <property type="entry name" value="ISP transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="15">
        <location>
            <begin position="179"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00072517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3207246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="256" mass="28432" checksum="D2150DB3E378C5FA" modified="2024-05-29" version="1">MLRVNQSTKTVFASLKPLANKTLNSPERLSHSTHYLSSNNSLNTKNPFNQTSKTNLISLQKNLVFKRCYSSLKASATYGDVFVPPDVEDYKKERKVGESKDERVFAYFMVGGLSAFGAVAGKNIVTDYLLHFAASADVLALAKVEVDMASIPEGKNVILKWRGKPITIRHRTQDEIAEANAVNLSELRDQQEDSERTKKPEWLVMLAVCTHLGCVPIGEAGDFGGWFCPCHGSHYDISGRIRKGPAPLNLEIPEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV53</accession>
    <name>A0AAD5TV53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001098">
        <property type="protein sequence ID" value="KAJ3206803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV53"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02181">
        <property type="entry name" value="GH16_fungal_Lam16A_glucanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF24">
        <property type="entry name" value="GLYCOSIDASE C21B10.07-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26113">
        <property type="entry name" value="GH16_XgeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041944971" description="GH16 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="13"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3206803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="308" mass="34188" checksum="E7C97167B1BEDC74" modified="2024-05-29" version="1">MLSTLILSTLLLSSLKSTSVRLTHDLRSNNLVDHFDFFTGADPTHGFVKYVDRDSAFREGLVKNEGGRFILKSDTGEIAFNGRKSVRIESKQAFNRRTLIMLDLDHMPTGCGTWPAFWMFGPNWPNSGEVDIIEGVNQQEKNLYTLHTSDGCMQNGEGQTSKLITPNCYVNAPGQFDNQGCAMESNTNLSFGKGFNQNKGGVFATLWVDDAIKIWFFPRGSIPGDILNGNLNVDSWGAPSANFKTEGNCSPNKFRDMKIIFNLTFCGDWAGNAYQGCPGTCVDFVKNNPAQFNEAFFSVNYLKIYAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVP3</accession>
    <name>A0AAD5TVP3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ATG8</name>
        <name evidence="8" type="ORF">HK099_008093</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000854">
        <property type="protein sequence ID" value="KAJ3211121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVP3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3211121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="105" mass="12347" checksum="E66946D33E59A092" modified="2024-05-29" version="1">MRSKFKDENPFEKRKLESERIRQKYPDRIPCLVEKNEKSDIASVDKNKYLVPSDLTMGQFVYVIRKRINLAPEKAIFILVNDLMPPSSSLISQVYQEHKDEDGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW34</accession>
    <name>A0AAD5TW34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001245">
        <property type="protein sequence ID" value="KAJ3204982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW34"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053086">
        <property type="entry name" value="RhoGEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45834:SF3">
        <property type="entry name" value="RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3, ISOFORM L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45834">
        <property type="entry name" value="RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="218" mass="25669" checksum="3F6152A27312F59E" modified="2024-05-29" version="1">MSIYNDYCYSYLNSLSLLAKLEKSKPFQLFLKDFGITSNEKLEIRDYLILPIQRICRYQIFLNELLKRTKSLKMEQNVAELEIALEIAKQTTKSSDLIIGYYKGNNEHNEHNAPLRINTWEQQGFHLKNNLQGILSKKNTIYQKGRSSFHIVQEHKNLEKEKHISSGEKSFEMLNKRFSVDISFLACNNSVKDLSDKKQVPKKRFSFTEWVRNKVSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW57</accession>
    <name>A0AAD5TW57_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001488">
        <property type="protein sequence ID" value="KAJ3203024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW57"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="147"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="681" mass="74541" checksum="54B974031194E681" modified="2024-05-29" version="1" fragment="single">ENLDIHYATKANNPVVVTTQSGFKLTTTSELSIYSKTASGAVEKSSQTQSGNVYTKTDIKISSTVSNSDTTMASKIESNVNSVIEKDAMERETLIQLSESTNTRTLVGSLDSVSSTTQEEKYYTVTSPNNHISYQVCSVKKTLVPSDFVFLIDASSSMCPYTQALASGFSDFVTSITNQKVDARFSVVVFGGPPQLKQSFTDDAEITLNTLKNIGCTEFGQESGLEAIRMILADNNGSDLVKKCAGNEQCSLAWRNGAKRVLIMATDEDSDRPTTLKYLVPGQENNGFCAVEYLKSKKSCSINSKTNEIYDFEPPFTPVSESYQTATVWAPAYNQFFQISQKFRSSSDPLKLTAPYYTEIELAAESLINTNTNLHLLMKSDFNRNPFQPVSSFNQHNWLYNQKSEKTPNLKSDDTHTSILQYGDPNQISQNDDLTGFNASLTLEKFNSKGLENSLVGKVLSKNGLARVYDIEQLINAKSKLLANFYQATLQSVSECDTFYYPTSELSSTTENLATNDFEHGTVEPSFEKITTAADIVPTESAFLASTETHDFNHGTEGVKLEVSSTKATGIADSTTASELVVENFQSTPVSTFDSNSKSFAIETKKGSVTETTSNAKGTITSLSEEIETEAFTTKIKETVDIDATPSNPKLTTTGSLTENTVREAFSNTDTVSTLYQPTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWB6</accession>
    <name>A0AAD5TWB6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_008012</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000837">
        <property type="protein sequence ID" value="KAJ3211389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWB6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042004789" evidence="3">
        <location>
            <begin position="21"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3211389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="430" mass="48951" checksum="01E26DCC6DEDCADC" modified="2024-05-29" version="1">MNFTFLILVFLLLASTPAVSKPLDQKALNLNFHNTTLLKIAHSKSLLLSSSTISSTHTSSISSTPVFSSTSIVSHHSPETTLIQSNANSTNFPSNLTESSLNFNSSTPTSSSIAPSASLEHNSLPPTTIFIIVAGIIFCIFLFTLIFLKFKNRNTNDNCIETPSNNTKHLNSDFSVYPSETGRIPMIPPQIRLTLSRRLGIFNTLSHIFNPGERPYSMARSGTLSSVYSISHYFNQNDWKSDLKYDRRSSEKFDHKNSYESEGTDILNYYVYQTGDEVDNKNRNSLKPTDSEGRKSSDFKSKNIFKQMEYEVRKSIDLRNKNTTKATESEGRKSMEKKKKYITNQIESDNRKSMDEKSKNFTKSTENDGRKSIDFKNKNLKKKYSIDIEIEKKSFSDDLFLEQKFKELLIEKKKLDINRNSSTSQLNKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWR5</accession>
    <name>A0AAD5TWR5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007764</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000786">
        <property type="protein sequence ID" value="KAJ3212282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWR5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3212282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="191" mass="22058" checksum="0D404DAB9B24D4B6" modified="2024-05-29" version="1">MYVMQVNLDCYEKIIANEKTDFVIEDEMDKFHEMASPNLSDANFSLDNLIIDPNNGKSLTSRSVTKSSLLSMEELLLVTKASLPKGCDIEVKELIKKRSTIKENFYDHDSIVASVEPDLSSKEITVSDTLCSDDNFELQSLQEFTRKLKYMLRIERYKKNEIKVYFKADQHDIKSNSQKFLSILDKVYCIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX26</accession>
    <name>A0AAD5TX26_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PTC2_1</name>
        <name evidence="13" type="ORF">HK099_006894</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000625">
        <property type="protein sequence ID" value="KAJ3214394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX26"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000016">
        <property type="entry name" value="Protein phosphatase 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF565">
        <property type="entry name" value="AT28366P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="12">
        <location>
            <begin position="23"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3214394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="354" mass="38953" checksum="61F90E49543D9D24" modified="2024-05-29" version="1">MGQTLSEPITTKQSEEGSDDRLIYASSSMQGWRITMEDAHTTILKLEDGDAKSTKNTSLFAVFDGHGGSNVALYCGKQLQQLLVSNENYSDSVESGDFTKPLTESFLNLDVELRKDPKYVDEASGCTAVACVISDDWKITVANAGDSRIVLGSKTGEAIPLSFDHKPTNDIETKRIAEAGGFVENGRVNGNLALSRAIGDFEFKKSTNLPPEQQVVTSNPDIIQRDLEEGDEFLVIACDGIWDCMSNQEVVDFVRYRITEKEGNLKEIAEDLMDYCLAPECDLGSIGCDNMTVIIVGLTRGKSVEEWVSEIAKKTELVSQVMKQKLKKQPLTPANYVEDSDSNVNGDVEEETNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXB8</accession>
    <name>A0AAD5TXB8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001986">
        <property type="protein sequence ID" value="KAJ3200023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXB8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050949">
        <property type="entry name" value="GPCR_Fz/Smo-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31787:SF3">
        <property type="entry name" value="FRIZZLED AND SMOOTHENED-LIKE PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31787">
        <property type="entry name" value="G-PROTEIN-COUPLED RECEPTOR GPCR FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="28083" checksum="06743B801A51B1C8" modified="2024-05-29" version="1" fragment="single">MIFYSGRSMFDLQGRGNLQCFNKVTTNNQLTSNSCAAQVFKSLWLTSRKWLMHISWPISIGLALAIYFVEGYGFETLSACFVNRKWINLFFYVPLGIFSVATAIMFIWTLVYIVGVQTKISTEKSSLSIETGKSTSKGKIAAKTIKSQWRMIFFILVCMTSFIYFLIFNFVFKTETLTIGAGTVWLQEWLGCVAATTEGGQNVCSSISAKHLPPYAVLIIYDLLIDLLPIWMFIIFGMRLSLYRDWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXT9</accession>
    <name>A0AAD5TXT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000555">
        <property type="protein sequence ID" value="KAJ3215269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXT9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="106" mass="12297" checksum="1AF337CFC538964A" modified="2024-05-29" version="1" fragment="single">MCSIWYSCCFTRNITSVRSTLNDLKSPVTSNIPKEYLDSKGNFGSSGNYGNKEKIHKQVEENFKQTHPGQIPDEQDDLFYYFSLHDYNHDGHLDGHELRSAFYLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY41</accession>
    <name>A0AAD5TY41_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nitronate monooxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000799">
        <property type="protein sequence ID" value="KAJ3212031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY41"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3212031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="38158" checksum="6C7935A02D47209C" modified="2024-05-29" version="1">MSETLVTPLSKSLKMKTPIFLAGMNVAAGPELCAAVSNAGGLGCIGGVGYTPDFLRKQIASIKKNLASPDLPFGIDLLLPQVGGSARKTNFDYTEGKLPELIDIVCKSGAKLFISAVGIPPVWAVDKLHAHKILVMNMIGAPKHAKKAIEAGCDIVCAQGGEGGGHTGDVPTSILIPAVVDACKGHFSKLTGEPIHVVAAGGIYDSRGLAMALSLGAQGVWVGTRFVCAKEAGAPPAHQAAVMRCGYDDTIRTIIFTGRPMRVIKNEYIMDWETNRRDEIQQLTQKGVIPYTVDQEKVTDPTPEDMKKLMNARPWLMGQVAGSIHDIKPAKEIMDEMTQGAIKILRENSLAIVPLAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY98</accession>
    <name>A0AAD5TY98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000508">
        <property type="protein sequence ID" value="KAJ3215952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY98"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3215952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="401" mass="46013" checksum="1FDA2C15417829BE" modified="2024-05-29" version="1">MEKFVTFHVMADLQQHGHIPSNFKCLDFLKPPTLEQSKKVYNSNLDARYADYKKLELKKSIQNFFDECCSRASIAKKALESIKFSANEVNGKVDRGDSQSPGGNTCGGSFVLDVLIDSFIVIFKKGNFRIEREIRHNLVKMVGKQHDFNGGNGTDYELNERSEKIEKESANQDDTDSVVEDETTVPARENSAKGRIIEVSKSLPKYIAMNKPLKFPEQIDTNIVFPSKKKKNFPPRKVPICTSERPTGTFHFIKTLKAFGRNMYLFKSSQSDIQNNVFEKRISDFGEVLHNLTKSIFLNENGANNIYYENSTSIAFCYKKTIYFNCAYWNENITDITYHYNYWYHTYAHEITHFTCPNHDESFTSTLNTLLVEYFPGLLNLITVISKDTLLPNFSALKVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYC1</accession>
    <name>A0AAD5TYC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Threonine aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GLY1</name>
        <name evidence="7" type="ORF">HK099_006010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000498">
        <property type="protein sequence ID" value="KAJ3216096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYC1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06502">
        <property type="entry name" value="TA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3216096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="371" mass="41657" checksum="5DE4EBC16D2D3D1F" modified="2024-05-29" version="1">MGSRYGNNGNKIKLKFDFRSDTVTRPTPRMLSAMLEAETGDDVFNEDPTVNKLQGKIALLANKEGSLFCPSATMTNQLAVRTHLTQPPYTVLCDYRCHLVNYEAGAHVTTLQPENGLNYLTAETIKKNLILDDDIHHSPTKLICLENTLNGEILSIEEIKKISELARFHGIKLHLDGARIWNACVATGLSLSDYCQYFDSISVCLSKGLGAPVGSVLIGSAQFLKKAKHFRKMYGGGWRQAGILAAGGLYALEHHLSGLKTDMENAKYVSEKIKSFGFTITKKTETNMVWFEIPKSYNFSVEDLKVQLEKFQCVIFGGKYDYECRLVFHHEITKEGCDLILEGLQNCVKTFATIEKDNLFEENDKKKYLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYH5</accession>
    <name>A0AAD5TYH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000745">
        <property type="protein sequence ID" value="KAJ3213107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYH5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="198" mass="23095" checksum="EE640676BF1BFC26" modified="2024-05-29" version="1" fragment="single">EPLLNLQNYNFGLNNVNEQYSNHLLDSMCIQQPFHNSQLLSLPNPFFDNNFLFINQTQLNNPQPFTSKQQQKSPKLNQGVTVEELLDIDEVLNFEVLTDTETKTENNFFLLNNPTSEEEELNTSFDFKKKLDNSIKEDLFNMTLEQIISNAKFDFSSAHLNDSIWFIEQSLKELGFNLLELGLKKEKVEEVIFDQIFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYN5</accession>
    <name>A0AAD5TYN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin domain-containing protein ubfd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">UBFD1</name>
        <name evidence="2" type="ORF">HK099_006614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000583">
        <property type="protein sequence ID" value="KAJ3214904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYN5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039120">
        <property type="entry name" value="UBFD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057455">
        <property type="entry name" value="UBFD1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16470">
        <property type="entry name" value="UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16470:SF0">
        <property type="entry name" value="UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25343">
        <property type="entry name" value="PH_UBFD1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="110"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="340" mass="39042" checksum="8CF7D61A2B8BC81D" modified="2024-05-29" version="1">MQSTTQNQILPYPRITHELKHSHSLPQLSEKSSKATLQQSNCKLLKGINSPWSFRNLHKIGEIEYNITKKPLISKDRLCLKEEKIKVNGDYKTIYLFNDLLIVSSNLDNFSVKLNDIKMKLDESIINFSLSPELLVKDFKTLIMEKTGIHENMQKLLYKGTLKDEKTLKESNLKDNIKVILMASKVEDILSINSQKNLQKSDDSVKSNSSASEIWSDKTEHKKILDKGRPDDGEEGKLNLRLRIPERGVTNLYNSRGVKTRLTFKSDLNQLWIGTAESTQKITYSSIQDVISEPIKGNEVYHILALKLGPTAKSNMYFYFVPCQYIESIKDQILGKWEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ39</accession>
    <name>A0AAD5TZ39_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Probable guanine deaminase</fullName>
            <ecNumber evidence="4">3.5.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Guanine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_006290</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>guanine + H2O + H(+) = xanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:14665"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.3" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000532">
        <property type="protein sequence ID" value="KAJ3215598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ39"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006147">
        <property type="term" value="P:guanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000022">
        <property type="entry name" value="Guanine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014311">
        <property type="entry name" value="Guanine_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026768">
        <property type="entry name" value="YPEH2ZP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02967">
        <property type="entry name" value="guan_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14976">
        <property type="entry name" value="YPEH2ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="12">
        <location>
            <begin position="92"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00083147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3215598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="829" mass="93422" checksum="0481470467FC7882" modified="2024-05-29" version="1">MGNQICIGFDEQKPEHSQAKKIDNFKSNMKIFVGPILHSFSPSDLRILNPGTIAVNNLGKIEFVQEGVHSDQLLKKFNLTSEHVTVLKENQFILPGFVDTHIHAPQYVFTGTGYDVGLLEWLEKYTFPKESEFKDSSHAHSSYQKVVKRSLRCGTTTACYYATIHLEGIYLFPNSLTVSFLASKILANVVKSVGQRGFIGKVNMDNNSPDYYVEKTEDSLNDTSAFIEYVNSLNSDLVKPVLTPRFAPSCTSKLMSGLADISREKNLLIQTHISENCGECEWVKNLFPEQNGYADVYKHNGLLNEKSVMAHCIYLTEEERKLFKEVNAGISHCPNSNFSLQSGVLNVRQLFREGITKVGLGTDVSGGYSASLLDGMRQSIIASKVIHMKSRDAAEENICEPLTFKEAIYLATLGGAKVLNLEEKIGNFEVGKSFDALLIDLNVGENGTSTIDVFRHDKIEDLIEKFVYLGDDRNISQIFVAGKQVMRSNERSQQYLQQQPELQFESFNIPEHSILRRSNDVNITTSELNITAEISRRIQRQNYRNIISARIRRLSRQPNSVNSLSHSSSTNNEESAVVSQRNYQSLSRTADSWISLAGNNELIQNENRNLNTTINNTVSNIDINYNNQNPLNHEEYFVSRRERLNTLIDRLNSNAEVFNRMLINTNLNINRSNIAYLNRNNSVNHNASTTSRRVNNNSPQFGSKVVCKIFCKFCKIKVSSRGMKAKLLADLKISSFSTDFNSNCVSLVNSEYKNGKCLCSICDFACLGCGNVIGYHVNQPCQPCLKACNNGHLWIFNSDHVYSVDENILWATLKLSDRDATDNRMEVCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZ49</accession>
    <name>A0AAD5TZ49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD repeat-containing protein wrap73</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">WRAP73_1</name>
        <name evidence="5" type="ORF">HK099_005527</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic/archaeal RNase P protein component 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000434">
        <property type="protein sequence ID" value="KAJ3217297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZ49"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3217297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="325" mass="38107" checksum="C444C5C263CE5BD2" modified="2024-05-29" version="1">MPNCLWVWDLLHLRQISLIFQNQNSVIKLLKWNPLKTDCFAFLCVEKDNVLEKTSATPNDDDFYSSNNSSFIYIWEGEEKGVKSIEISSAGFNVNQFEWNSDGESVLLMDKEKFCLEHKHDFIKEMESQLQFLFQAAYSTLKENPELSRHYIKLFNNLAIANDIKIAKSEKRKTCGYCNSIFIPGINCFVRIRRRLENRKNKDVVEKLIEIENDSVQQQQLQYVSERLKKCHQPLKKHTKRFLVNKVFFTCKICYTSTVISGSTLNHLKELDSRIKLDIFEKNEISDSYNDINTETKLEFGKNKQKDIQLEDNNGFSISDFMKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZA4</accession>
    <name>A0AAD5TZA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000418">
        <property type="protein sequence ID" value="KAJ3217602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZA4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="869"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1170"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1171"/>
            <end position="1184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3217602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1249" mass="141496" checksum="8EED3874BB926819" modified="2024-05-29" version="1">MDLSDTLNQPEEVFKSFDISFSAANLNISQTQLDNINSDLAKLYESCQSISAGKMRLQWSLENTEFTSTKLDFEIPANSLNSSSYLVKLNASYGAEIFTYTTILKISPDTFKISLGGSKMLSIGQDLNIIPIIWKNGYLTNDFSDFILTYQLYNLEKIITTAEITSNEVIISNLSVGDYEAMFTLTSGFDSYTTTESVLITVTNTRLNTLNLYYNTPNPSISSKNFYLESTIENEDLTIASEINYVLKKNNCDFILENDLKDANTVEFFDFILTPRGSNIVKFAPNFLEQDAVYCAESIYHDTLYNSTIISKIEFTTLPIPKGGKCFSQRSSGVPMHTIFSFQCSGYLADSASTQLLYMFEIRYFNDLTVGHWILFQYSQDQILETILPKGKYEVKTSVLDQFNLIDYHPTILTVTVEEEEPVKNVTIENLTGLSCTFPSYQCSQLQNNEFYSTSFYQCLQSGVWSKKLACPSKLGCYETLEIDIICDWPQNHNLKKRFVDINTVDSIISYINSANDILQTSNSRSKALRNLATSSLLFVNSNSSDYYVARLEFYNLINSILEKSFFIDIKTTLNSISGSLQLVVQSGNTFLSKSEITLVFNLLFNLLHIADEKSSDESDLVAVQTLTEYSYNIFGVLIQNSAVLTEFNEIISKNYLDFMSTLDNFHLMERVCQQNLAAFEFEQVTKMIGVEFNLKNFENEYLYKIHFENENLNAKQCYNYILTLIKNSSSILTNIQPPVIEGFNVISLNENLVQIKIFNQTSSFLTEKFWNENYLTLQNFTVNLPKFNSSNFDFQTCGYIQINDTENLVEHINWQTKNCELVQYNLTNIVCFCKNLPSNLLFTTLYYKNSTNTQTLPTDISPSDNSNWQLIGIIFLVVLLLILAVLSGYFLWKKKTFKLSKVHHSDESVNSVVIRNNDLVEVKISKPEDTEVTSKNRSSQPAVDNQNKRIHPFTEIDNNTTDISNFQESGFQADGANSNSKLAELSMTFRDSSESILGINYKPTVIKINPSNLQKGNLADWKSSINKKLQEIKRTSVITPNTERRTSQLLFDTNNLHIISEDFSPTGTLTLEKNEIYPYDTSVSKRSKSLKKQQKANNRFSVNSGFRINNQLSAKAKSLTLSSVEDEIKDHPESVDLGTVGEYLKSGFFVEDEKDATKIEKTLKNVILTSSNGNDENSSNGNEPLLDKNSNNGILQTLQTEKKQNFTDGSDDMNSTSLTKNDKSLLNSIQSEGEHANSVRSSVSFIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZC6</accession>
    <name>A0AAD5TZC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_005124</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000389">
        <property type="protein sequence ID" value="KAJ3218251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZC6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.20:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000019">
        <property type="entry name" value="Bc1_11K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="12">
        <location>
            <begin position="8"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="17"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3218251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="72" mass="8239" checksum="D65631C9A2E0C434" modified="2024-05-29" version="1">MSDEEVVDPMPLIQEDCKNSHHCHSIKDKFEECNIRVTNADGSTEETCVEEFFDLMECVDHCASDKIFATLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZP5</accession>
    <name>A0AAD5TZP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Follistatin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000480">
        <property type="protein sequence ID" value="KAJ3216409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZP5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003645">
        <property type="entry name" value="Fol_N"/>
    </dbReference>
    <dbReference type="SMART" id="SM00274">
        <property type="entry name" value="FOLN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042178574" description="Follistatin-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="2">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="2">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="2">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="2">
        <location>
            <begin position="161"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="2">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Follistatin-like" evidence="2">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="272" mass="29428" checksum="7F789C532FB28FEC" modified="2024-05-29" version="1" fragment="single">MKLIVSASIFAVAVSTTSAISCPEILRTCLGVKCEAGSSCKVFEETPFECSKVECVKDQVGCPQVMPSCENVACNKLSICEIQPQTATECAKAVCVPFFKPAPVKCPKIMPTCENVACNKLSVCEIKPQTETECAKAVCVPFFKNPEVKARGLACPEILRTCRNVKCDAGFSCKYFEETPFECAKVECVKDKPIVCPEILPSCDNVACNKLSVCEVKPQTDTECAKAVCVPFFKPRTPVKCPKIMPTCENVACNKLSVCEVKPQTATECAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZR4</accession>
    <name>A0AAD5TZR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carboxypeptidase Y-deficient</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PEP7</name>
        <name evidence="8" type="ORF">HK099_005843</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000475">
        <property type="protein sequence ID" value="KAJ3216493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZR4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036531">
        <property type="entry name" value="Rbsn_Rab-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140125">
        <property type="entry name" value="Rabenosyn-5 Rab-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="482"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="590"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3216493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="872" mass="100498" checksum="E7976D572F45F6BC" modified="2024-05-29" version="1">MHKSESFSGTSSIKLQKNATSSGRQSASPLRQSSILTHSISTDQINKKNVCPICNNAFPTLLHLNKHLDEDHVNDEEPSEQIIGWLKSVQKKVFGAVQKNGLSLDNLNIENVVNKINNEEVFELNSSDGNRNFDGSDIEDKFVSRSHWQLEGNTCNHFKCKNSLGIRNGKQNCRRCGKLFCEIHCSLQMKLARDTRHDLENGHWSRFREGYHDTQGVQRKRTNFFLKKRKEKVDKVRLESNMLEKRLEKISKLYLGERSLSKRASIANLTGFAVGSNWKKLEKELVPWEDDNLVESCPDCRCKTLSTRRKEALKELDAKPVVVLLYQEMKQIKTVVEEKLPLFNNMLFDLRSKSVIKPDDADYHSTARARKVLIDLLAQLDGLGKKVKNLPTESRSLAKLHFNIYLSTVEFLQLHMLTLQMMPKVTKEKEDNVDEYEIKTVNFEALKKAENLKISLNILKDQRVQINATLETSLKRRKFEDCEILKENLLEIDEGIKDLEREMMSADDEQLFGALEQLTPELKIKLMQLLSQDDSIASSIANTNRSDDKSQKQIASLRRYNTKLQEDLYKTLQDYKDAQQSHQKEVCQLEKDLEQLKAELNATAQSALESDLGRKKLLKEKIEAVKEKNDAKMDQEIISDLESRIENLELEQENLIKIRKEKDEELIKMKHELDIKDSELFIMKENVQKNEYWKEEFEKLSKFVDHLKEELEFERSRNEGIGYEDALGEENAKAVTSTKKTTKSKGFNSFADEALKGQPNENWEWTNWFDRSLSKLWERDIDGLRSEINDLSVNKDMAFTRIRENVSGMMGSTLDMVVPTSVKNVADTLSNTATAIAKGDTNSFLNKSTLKIVQDTNKDHEINTSELNKLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZT4</accession>
    <name>A0AAD5TZT4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan 1,4-alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GLA1</name>
        <name evidence="10" type="ORF">HK099_005797</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal (1-&gt;4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000469">
        <property type="protein sequence ID" value="KAJ3216604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZT4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004339">
        <property type="term" value="F:glucan 1,4-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000165">
        <property type="entry name" value="Glucoamylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF9">
        <property type="entry name" value="GLUCOAMYLASE, INTRACELLULAR SPORULATION-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00736">
        <property type="entry name" value="GLHYDRLASE15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042106614" description="glucan 1,4-alpha-glucosidase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="GH15-like" evidence="9">
        <location>
            <begin position="50"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3216604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="502" mass="57307" checksum="7D481ED3B5C40237" modified="2024-05-29" version="1">MNIIKFISFSQLLVFIASCNVHASLSKDIDDWLKVQVPFSTIKIKNSIHPPNSVNGILIAATAKTDNSEPDYLSHWTRDSALVMDTLLSLYEKSWGSEQQAYENLFWDYAILSGKQQKMGPCQPYIKYECEAKGGPGEPRYFLDGTIWRFGWGRLQNDGPGLRASTLMRFANLYIQKTGDVEKVKNILYTPSNFQSVIKADLEYIAHNWYNKCFDIWEEIDAHHFYTRMVIRRALLDGASFAKKFNDAGAAGYYTLQVKNLEKSLEAHWNETGGYIMEQIELNSTPERPRTQRNIATILAILHSYNHQEDFYSPISDKVLSTVLQLQLDFLNEKTYEINQIKFDSNNLPLGVSVGRYLTDLYNGTIYDSPDHSKDEGNPWFLTTLAVSELYYKAALLFQSKPVTITKLNLPFFEFIGADMSKLELDKTYQPNSEQSNNIVSRLLVSAENTVRTVKKYVGGSPGTMKEQFSRHNGKQLSAPNLTWSYASVLSVDYYRNVIKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0D5</accession>
    <name>A0AAD5U0D5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000496">
        <property type="protein sequence ID" value="KAJ3216132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0D5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="344" mass="39510" checksum="09BCFBA487E76742" modified="2024-05-29" version="1">MLSTISESFFKTKNTLKLKVNLKSHSDANLHSTELSKRNCIFSPTRKASIKDAHSIPTNIFHTIIPTKNSSNQSESLNFLNLPAEIQADIAMLSGFFGAIAMRGTCKKLFELLNNRRSWYSYTRSRILKQKSMEILSSVDEIVNTVTIVTKIHTFDHLIFGEWKKSLDSEENPTIFFEHRAFSDKYGGLKINLSKGGLINDSDFFDHRESLPCYVEYVKNQMSEVETENGFFQEQVVPSTIGGIRVDHSCEKCEGYDLKEPFNSIFIFDQIPSNLNWKNDGFTYVHEFKDKSRKLVFNVIPYKNTAGFTNLEELPWVTVNSIRINDRKLNSHQFELFKRLANGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0E6</accession>
    <name>A0AAD5U0E6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004342</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000300">
        <property type="protein sequence ID" value="KAJ3220465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0E6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="189" mass="22426" checksum="035D636ED67858E2" modified="2024-05-29" version="1">MEKQSLDAYNLYKLSIMHWVVATENRRVWSKGEFMECVQRIKGYDVLFLDCLTQWAAGRKYFKRNGVDPEEMENEFLYCEDCYWKRKESSALNKELNYAKKSQKLMEFKEAKIAKLRENVFLDIAKTCTSEEIQLLVPQTLNSPILKNFCCYSIQVELREEENIGQREKIVLLTMISHNPYSYNKTVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0H7</accession>
    <name>A0AAD5U0H7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PP1_2</name>
        <name evidence="12" type="ORF">HK099_004221</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="JADGJW010000293">
        <property type="protein sequence ID" value="KAJ3220531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0H7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000007">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="11">
        <location>
            <begin position="121"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3220531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="38220" checksum="A83F4188D5EB5DEF" modified="2024-05-29" version="1">MADNPEADIDSIIERLLEVRGSRPGKQVQLAEHEIRYLCTKSREVFINQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIIDEKIFTMHGGLSPDLQSMEQIRRVMRPTDVPDTGLLCDLLWSDPDKDITGWAENDRGVSFTFGPDVVTRFLQKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKTKYVYGGMDHGRPVTPPRKQKKSKDMAKTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0L7</accession>
    <name>A0AAD5U0L7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_004151</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000287">
        <property type="protein sequence ID" value="KAJ3220614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056342">
        <property type="entry name" value="HTH_CHD6-9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF11">
        <property type="entry name" value="KISMET, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23078">
        <property type="entry name" value="HTH_CHD6-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Chromo" evidence="8">
        <location>
            <begin position="141"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="8">
        <location>
            <begin position="212"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="314"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="592"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1234"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1327"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1501"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1237"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1327"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1344"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1501"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3220614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1682" mass="195625" checksum="ACDCA03AA894E2CD" modified="2024-05-29" version="1" fragment="single">MFSSSSDSDLGKSKVKSKKKELAELFDSDEDDELLDDSEEELTPVKVLSSKYHSLSSPISSPIKKRKEDEYIEYDDDMEDEIEEMDDEEDGNFSNSENEESQPTTKKAKANSTSSNNDSQKKSKNKLIHFESVHVPMGDKSVIEKLLDYRTENGKEEILVKYKNMSYYHAEWLARATIEEQKLGKNRVKRFLDKGIYESQWSQDESFNPNFVKIDRLIDEGEVEQGQIYFLVKWCSQTYDLSTWETEETVEEIDPDKIEEFHQSRVLTDARKLSYEKGFQRPPAKSFKKLDGSPVYKNDNTLRPYQLEGLNWLLFCYYNGRNSILADEMVTPLSTIGNWEREIKTWTTMNVVVYHGKESARNLLVETEFYFKDSKGNFIPNIFKFDVVLTTYEMAMSGLNHLKPINWRVCVLDEAHKLKNTTSKISETLKLYKMDYRLLLTGTPLQNSLDELWSLLNFLEPDRFPDEKEFQSEFGSMATHDDVEKIQALLKPLMLRRLKEDVEKSIPSKEETIIEVELTTMQKKWYKSILEKSGAKSKNMPNLINTMMELRKCCIHPFLLKGAEDQIISEYSADTAEKQFAALIQASGKMVLIDKLLTKLKAGGHKVLIFSQMTRCLDIIQDYLRGKRYGFERIDGSVRGDLRQASIDRFCSRESESFVFLLCTRAGGVGINLTVADTVIIFDSDWLQAQARCHRIGQTKSVQIYRLITRNTYERDMFDRASMKLGLDKAILQRMDVNASMREEDPFESKAPSALSKQEVEKLLKKGAYGAFLDDEASEKFCEEDIDSILERRTQVIKHDSGVTTEKGSIFSKASFASAQSNQVDIDDPDFWDKIAAKAELHIEEPLDELDTLIQYEPRQRRQVRRFGADEIGGDSDDDDYNIGDSVTSNNSAADPSIKLWSITEKTRFERALMLYGYGCWEKILPLFPRREEKDLIAVTDLIMKFCIKRSIQDPDLVRDIRRILDIEITDESALDENLENPIRLTEDIILPEIPYEGATKKQISEYRSFLLDASKEYQEHIERKSKNLLNRIQMLYGIRFRVQPHPEIEMPPILGNPPVPWWGADEDRDLLLGTLKYGYAAYDKMRYDPEFCFNKRVYIDTLESVTIDELAEAKKGKISELPEGQENSGKLSQNNEELQDIVKENNDVKKMTIEGGETDVETVDIEKEEKLTKEVKNTTDDASSELSQVEEKVLDAKEGEAVKWPGPADLGVRIRRILAAFLRQFATIARRSAKKQLREEKNKEKRTNEAERRRQFTKKERIEFRRVLLSFGVETDPNNRNVRIWDRFRYLSAIHKTDEVLEENYLNTISMCHECIEKAERIKDGKESKDELKYDKDDNKDDVNDENEEKDEKDDKDDDDKDDLKNFRIERGTESISLEIARRMLKRIEMMRKLREEIITHPNIDTNTGNIKRHQRSGLPSWWLPEHDKYFILGIARWGITRTDSMVEDETLPFKKMQEEWQRKRDAGDEVACKDERFWMKETVAGRRFDSLCEAILKPPQKKNKKGRKKRDDDLDSDDDAMWQGDTVKKKMKKKEVSPVQRQSSFSPIKKKKRKGKFNDGGYGSLDFGNPDDMLSSENESGLDRVLHRIKRERKLAKKLLFDNEESTIILNNAGNNIFQKSYFKRIKRDLRKDWKKLYFNKNIHEEKRNKLPPLENETNIFEVLSLAGNLIAECRKETEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0T8</accession>
    <name>A0AAD5U0T8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Fatty-acid--CoA ligase FadD10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FADD10_1</name>
        <name evidence="9" type="ORF">HK099_005085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000382">
        <property type="protein sequence ID" value="KAJ3218395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0T8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="7">
        <location>
            <begin position="589"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="8">
        <location>
            <begin position="1036"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3218395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1125" mass="126438" checksum="635CDA33101B1CE5" modified="2024-05-29" version="1">MSQFFKIYEDFVGLQPNSVATPKNLFSRESLNQSLLMEANHLQLKRRNSIFQCEELKKLDLITLFQPSKRIELSVQEECQKLGDSFTFTHRSATSINAFQKTPKCLKNIETLSTEEYINFLKENFVKDASRISSPFRIAHQSGPLPFYIKHLATLLTTLNQNMMSVYGSPTLSIIEKETIAEIHKDFFGGNYERSINECYGISCSGGTVANITGLWVARNRALQCDNSGIEQNGLYSVMIKNGYAGVAIITSCMNHYSIKKAAGIMGLGESSVIEIDTDAEFKIRTDLVEEKVKELKSKNILVVAIVGIAGTTEVGSIDNMIELGRIARDNNIHFHVDACWGAPFIYSSKFKDLFLGIENADTIAVDGHKYFHTPYGLGILLYKQGSYSNFIQKSARYAIRDANDLGKYTLEGSRPGNILYLHANLSLMGKKGFAESVEAGSKSAFTFSKTLKLAGRSVQIFNRPQTNILCYRFIPSFLQRKNLIFSNKEESLLDYFNINIENIQTKTGKCFVSRTKLKVGKKVHHVLRVVFMNVMSTKDDLNFVFEEQLKISFILEKKFDNEIAFTSKYPDFILPEKDTVSFIFDDFSEKEKTLVALVDDSTGQKITYGNLISNIDSFAERLSCFDKWEVVGVYSPNNVEYPIAVYGILRAGLTVTTINPEYRLNELIYQLKDSNAKFLIVHRSLVCIALEAFIKLNISEKNIIVFGKKKCQKLKYFSEYIKCKPSANINKRRTFSVKELYNRPAFLCYSSGTTGLPKGVKTSHLVETMKYEIFLPLFFKNMISNLIMENTVEKSDCRPGDMFIGIIPFYHLGGLGEVLPIAFMNRISVAVTENYDFNSFLKALSKWKCTTAHIVPPIALLLAKSPETKNHDLTHLRLIVTGGAPLGAETSQAVKEKLGIPIKQGKKTKFNKKFFVKRSIMVAYGMTELSPISLITVSTNIVEGSVGVLVPNQIAKILSPEGQSLGFNQEGELWLKGTNVMIGYLNNDVATKNTIKNGWLRTGDIAKVDEDGNFYIVDRIKEIIKYLALQIAPSELEDILLTHPKVIDAAVIPIKDEKAGEVPLAFVVLKRGVTAIEGEIKEFVSERVADYKCLRGGVKFVTSIPKSPSGKILRRQLREFYNCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1A4</accession>
    <name>A0AAD5U1A4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000272">
        <property type="protein sequence ID" value="KAJ3220803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1A4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007541">
        <property type="entry name" value="Uncharacterised_BSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33321:SF12">
        <property type="entry name" value="PLANT BASIC SECRETORY PROTEIN (BSP) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04450">
        <property type="entry name" value="BSP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="558" mass="64354" checksum="BF4E78B63BE01A48" modified="2024-05-29" version="1">MPPIDAYPKPLIKIIHDISSNDESILSKAIEVSLEEYIEEIFVKVLQGLYPKPEKIKKKFEQVILEIKPINGVAQCSKNKITLSSKYILQIFNKSGLKGVSFEITGVLIHEMVHIVQNDGKNHEGKTINDGLAEGIADYIRLRANYSPEHWSEKKGKEWDAGYEKTAYFLRWIEDGTLCIKDFVVNLNDKIFEIGWDDEIFKHLTGVEVKELWKMYQNSINSDDEEESDDDNTECDLDFTDCDNYDENFSNINELHFKPQYIFKNKNLNHKGSDLFNSVISNPVEFFKNCSEKSLFVLYSSKPKKSYPYFIKRISLTLKEMNGVAYCTGTKRRKDINLSLNYVENVFNKNGNCLKKLKSEIEGVFVHELTHAWQWSEKVDKNGNGEGIGVAPGGLIEVWLINKLKKLKSFKIQGIADYVRLQAGLNPPHWKRVKNGEWDAGYDKTAYFLQWIEVKKNITNFTRKLNLLIGNQGYYNSHFVSLTGQSVENLWEEYCNEGKVHGSLARAGKVKGQMPKVEKQEKKKKKTGRCLKRIKYNRRFVNAVAGFGKRKMNSNEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1C3</accession>
    <name>A0AAD5U1C3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_003695</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TMEM43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000245">
        <property type="protein sequence ID" value="KAJ3221190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1C3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012430">
        <property type="entry name" value="TMEM43_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13416:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07787">
        <property type="entry name" value="TMEM43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3221190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="414" mass="47556" checksum="BEE94DF5FDC4D692" modified="2024-05-29" version="1">MFRVGRTRRLHPVENQSTLYLEHSKKLMMDAFYEAEQVMIHIGDLNHFHKKPIENTLVYINSVNPSNIVTDSILTDYDFDLKFGDALKARRNVEYCQWVETSTDQTIGEGENQETIRTYHYYKSWQTTRIPSFFFDQPAAHHNPQYDPFPSTSFQVEKVSLYNNNGEKKFDLHKELISAASPLILKKNYPKKDLEGFFNSKAHENVGFRYIGQGYFYYNHEPTFFETFLRASGMGLEGTLLDYQLGDLFSQCNAGDIRVSYTQVSKREGLSIIAGVKSDQGDLNTFLTSKNYEIGFIDSGLISPSEIFRKKIQDQKAILYIAYFILFLWCLPVQIWANRNNGISILVIGAVLIWISSLGGIKLFVYGFKKNLILQILLGIAGWTHLNTLKKNLNENSESNEAESSGNLREEKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1C7</accession>
    <name>A0AAD5U1C7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000532">
        <property type="protein sequence ID" value="KAJ3215599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1C7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="629" mass="72290" checksum="A337FA56D3F4E885" modified="2024-05-29" version="1">MKLEGCLIISSFTIGVIDATGKVVLINTELYDANLIDAIIYFNHYIICSTNQDYLIILKIENIEANEVYANDLNSNKFYIPTCKRLAQIECIDEEVAILLEISQNSYDLYYFGQSPPTNSNLLNLTKKSKCNIAYSVACASISRNCTLNRSVVLYFTTPLGKLYTLSEDVITERLDIQHQTLNIIIYGKEVLIFGFEILSLFLINVFIRVDGKITVLDSNSAQKKHYNLYKNVIKAKVDSKGNLITLDDDAKLQIFGLPMISEGKFRLISGSCLDFGCSLNSKFIMYVVSSGKLKVCNIENSDCNGENIVQPLSNWTDYIEKLDFVKKSKERTLQTFVQSIENENVLTAVLNEFVSLIKKKKKIVKFKMLKKFSDVRNEPYLDLEFKFSDDIIKNFQSLDVKVIVVLSPLERKNGSTVHCFGTNNQHWKFQIEMKTFIFPITVEMYLYLNASTINGFKSEIGEFPELIFLCKKYVDDLDYCLPQNVPVQNQYHKGLFNNRSDFENCACIGMEKFNGKATLNFSLKNDIFFQDNYRKILPSLFSYHEYCKDIVKTAEKALFKISNIDVALLLTKKNIFAEISSCQSGDVKSDEYINFELTIKCINFFLLIKVFKCCKLRLMEKQWVHFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1F2</accession>
    <name>A0AAD5U1F2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000698">
        <property type="protein sequence ID" value="KAJ3213565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1F2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="69"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="176"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="298"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="749"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3213565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1179" mass="136909" checksum="6B4BDD892CC54E6F" modified="2024-05-29" version="1">MQTLTEKYEDELKVLKERLRIETDEKVKIQELLHCQKDTYEKDFDEKATFIQNLEKSRVTLSEKCDYEIKLLKERIDGITDEKVKIEELLNCQLDNKKKEISEKTDLIQNMEEDMRTLTRKHNKELDVLGEVVVNLENEKMNIEKLLKAQIAVKDTEIAEKIIFIKKLENVTVTLTEQNNDKLKLLKEKLNFLEKEKVEVEELLILSEEKYSELESLTASNKESSQLLIKNLRCQIDKYLLEKLAFEETIDSLEENTSILKKRLDLQILSENEAKTKKEELLSIMKKKDADNSILQEKNEFLINENFLEEKLRLLEERYSKLEEKYLVAVQNCEDYEKASLKNVNELKLMRDHILTLNEENFLLKGTVETQSVSISNKLDYEKKLSKEFTEKYSILASERDNYVKIVSKLQQEMFSLQQHILEFGLIKDEEKENVECQLLENKEKSVEALTTLLNDCVKNTDSFLESETGFENSLKKQELILKASESAKNDLQLHVGKLLTVNRKLNAKIESLKVKIESLVPRFVTEVREICNSLLPEFFEFEKSLSEKNLYNPDSPVNLVCGIHYILQKFCIFFQNSEMFSDSSLEILDFLKTSYLDKGKSLISNMVADVDMILSERKAILLFFKKLEKEIKISYAGEKINVEDMCIYFLDKIKELSNFKTKSLHHKKNLKKNVEDIVKINLANVAVNTTTPTQVEKKVQISPVMLSEYTQCSHIGDISIHRNDTPKIVDSFAQTESFENKQESCVENTKLKNLAFKLNLRVKEMEEQYEVKNDEVIFLQEKTELLEEALAIYKRKLSDKSVPSSPVINEDQNIISSPRNVAIEKFEVTDEEIDNMDMEGVNDIALESKKSVMMFDLNTSQISTIQKKSSIKELTSESNSVFVSEEYIEKKLYIPLQSHKRNIDADFEVIFQKSKFESSSVNSVLIPTITDVAVTEELLTKANSDVSKLIENFKYTKNHGTTGVEEINYMEMYKDHTEEIINMRQASKSSLEGTVSTLESFYRKEELGSLDFSAEEVDVRKYEEEMHFLRNETEKSISTTADTLKNLYGIREDKCVEDIDAIKLATKNSIFETAKTLESLYGTNIEEDELGNFIYLFAVNIVELTFLVSKHDEKMQLYRNETRNSILKTVDTIENLYELKKEIELDHGADNHLRLDQSSTDGFRNYQNDIRIGDNDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1P6</accession>
    <name>A0AAD5U1P6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000332">
        <property type="protein sequence ID" value="KAJ3219652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1P6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="310" mass="34355" checksum="F927A6AA91AB8DA9" modified="2024-05-29" version="1">MNETEKLALDKLHNDRAFEFQKFAGAMVAGTCISVLAQVLNRKKSSRLNIYQIISLTAFLLQSFAFAAGNTNIASDFTIYSIVVGLIFISLGRVFHCELMNYFFIMLSKTKTRPLSEKILIGTARLAMCCLFLSAIAESVFSILGFISTGTQVEKDDLQEKYVLTNNLWNAFSLICVVCNSIEFILVLRIISDGSRICRDKARGESQEKQIKVIGAVILITEIVVSIINVAFASAASAFGMKWLLNAQYGIFSFGIIIAVIGLIHLQDVIVDYVKNKKSLSSNTGGAFSVSQSHTKDKEATYNVQYEKTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U203</accession>
    <name>A0AAD5U203_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000391">
        <property type="protein sequence ID" value="KAJ3218206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U203"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00014">
        <property type="entry name" value="CH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="3">
        <location>
            <begin position="254"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="642"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="849" mass="96620" checksum="97AC848AFC483EB4" modified="2024-05-29" version="1">MESPSFSTYEIVDFFEQYVVESGAVHIPNNFNLNDAQTLHHLVVQYLQFSRIDSSDAKITYDDYGGQIRISNRGLRIMDNFIQMKHFGRAAIVIQLFWKRVKARILINILVDFVLTDILAKKLTEKPDWQYEPITLVENSVKKQQASQQIHLLEVPQENKEILTKKLTKVVSNTKPVNLKKHLHRVSVAYQGILAKSDAKPSSKIPSLDERAFMKLLNSEETFKLSSIVQESNFFSETPMVLKSSNSSSFQTFEQYAPKVINWISDVLAIPIPLKTFLPSLLASGDILCKLAVTLYPKIECHLLNKGPEYAIHKIIFFLELCKSLGIKPSLLFSVADLILEDDNDISEENVSKKIKSALTVLRTICAFERQARKKGWKGTPLRIGSSSSNNDPSEKSEPRKTSEKPGQSSKRREKQQFNSIIGEQRVNSIYGYYSEANTTATHLEQNGSQTATNLQQRQSPVSNSSSPPTEYNDNSKNVYEILPSVENSIGLGFDEIINELGSYGLKNKQLQLLQLNEDNLIPPLTAQSNQSSPLDLPDYSYPVQNYSIETNGLDQVLDEGENYDIDNSRSNHAEESDFENGKNITDSFTVDDYYTYEGESVQHSHPFTSNYEVENPVITAQESLEVIKKMKEVEAMEKLDMRNEYIRDFVATEENYIDVMESIAAFLNGIIRRRNRVSKRASAILTNDLTQQDISKYDQENVDLLSLFSVVEDIISTHRNLVQSLEYAVKDNSFLSKVGLQFLNFSDEIMKPYISYCCLLLNPSEGLHKLVEEYKKHLNVDNMENKYKSNFELDEPLFHMLTYKNSFHNISDSGVFEGSKVKGDSMIIKMAWLKVNAIANVIKDKLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U285</accession>
    <name>A0AAD5U285_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002941</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000200">
        <property type="protein sequence ID" value="KAJ3221937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U285"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13535">
        <property type="entry name" value="ATP-grasp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="145"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="786" mass="88459" checksum="713A0289C4F57B26" modified="2024-05-29" version="1">MGEKIIKHTITRTPDVVPQTLVLLMDSYDSNRSLFEITDSKFMTIDIIHIKNDHLPQQMANFDRMNKKDTQSFKHHIIDEILYEHYYTCIKEIQNKTTIGAIAVSSRKESLVEISARLRVEFAIPVGTDLACATLFVDKHKMKQKVLEKNIVTALMSDAVLSKGNELIKETGFPVVLKPTKETGSKGVQIIRNRTDFELQLKDIQGKSSQYILEQYIDGDLYRVDGSIENGEIKFFAAFHENPSNYEYFTNRLPLAEVLVKDPQEKKDMKKIANEVITAFKFLNGVFHLELLKNKIDKKFYFLEIAARPGGGAARTIMARHGADLTVQMIRLESGLKGEFLDLPDELHFASVSFLTPDRNKTFIFDSINLPEKVYYKTLKTIDAPCGGKIMGEYDAVNIYFTCTDEKLLLQEVNKCKESLKVTYRSKSALFLPPEVSKGIDLRSDTLTTQSEGMRLYMLNASMGDDCFGENTTVAELEKYCAKLVGKEAAIFVPTGTMSNQIAIRAHTRPGDEVILDACYHINFYESAPTAAFGHVSTNLIRADRGIFSVKDIQKVIDSKPRGPLYSKTKLILLENTINAGGGAVLPLENLKEIKKFADTEKFKIHMDGARLLNASVAAKMKPSELAKYADSVGICFAKGLGAPFGSILCGDREFIDRAKIYRKWFGGALHQAGFMAAAAQYSLNEDWENILQRDHDNAKFIESALQNILPIEKVTEVETNIVIVDLDGLCEKMEMIEALRNNGVLAFPWCDNKIRFITSRNVASFKEINTATDIICETFKQFIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2G6</accession>
    <name>A0AAD5U2G6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000305">
        <property type="protein sequence ID" value="KAJ3220423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2G6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00266">
        <property type="entry name" value="TIGR00266 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43657:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43657">
        <property type="entry name" value="TRYPTOPHAN RNA-BINDING ATTENUATOR PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="249" mass="27036" checksum="F2D0C2D085C61647" modified="2024-05-29" version="1">MSYHPPSHQYQQQLPPPQVSAQNHGSFGPFFYQTMYKDANTLLKINFPQGEVITARAGAMVGMSPNIKIEGKMKGLAKLFSSGKMFEQKLIAVGGGPAEVLLAPRFLGDILPIVLDGRTQFNASKGQFLAKTQGVEKITKSQSLGSGFFSGEGLFIDVFGGQGLLFLQVLGAVHPIDLAPGQEYVIDNGHLVAWETSTRYCTVQASGFFDSMKSGEGLVCRFTGPGRVYIQTRNPEELKAWITSVVQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2H3</accession>
    <name>A0AAD5U2H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000179">
        <property type="protein sequence ID" value="KAJ3222358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2H3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="628"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="887"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1124" mass="118481" checksum="B1432C009C3ADEF9" modified="2024-05-29" version="1">MAICKSPTSENTSAKKKEVSEQKEVLSEPSNSVKRRRGYRFIDSDGEKEDDNVTLERNLDFRKVLNKKIKIDTVTQGEVVTTVPTRPSDNSVDIVLALHPPAIPVENSQSFPFGRKRSYITTENGQLTLKIVPNSPAKYRPVVYKRLKRTQNGDVSSAKKKNSHSDGEDLDRDSYKNNDEYYKRFKYCTLAEKNKDAREFMEAAYIKTRPDLFSSPSSAGSKGSVENKITFYEKVTGEKPPLCRKQTAKSLASESFLDKITKNSTDFSENKTKASAPSVEAGLSLIPTCAASNVVENDKSFSAQKAAPVQSDVGIPKFEFSASTEARKIEEKSTAIPSSALHNRFFSNVSENKPAVGSKLRYSFTVPKSTPSTSDQASDVASTSNIVDPPSQSPFTFGQTSTKFSTQAPPTSAALSQPPTTLDQNFAPSTGVTSSFGQNSASLPLVTSTLPQSTSSFTVSPALPVAAAIDKPVPANSFEQPPNPFSQPSSAPAPTSSGQPSNPFGQPSTASPTPNKQSGFTFGQSSSVSTPAPFAQPSNPFGQPSTAAPTPNTQIGSTLVQPSATPIIAPLKEPSNPFGQSSTATTGAFGQPASTFSFGQPSTTSTLAQPSTTSPFGQPSSTSTFGQPSSTFTFGQPTTTSTLGQPSSTSTFGQPSSTSSFGQQSSSSFSFGQPSATSFQTPSMPVSSGFGQSNTSNSNALGESASSNTFGQPTNVFGTSSASTPFSFGQPLNQTTGPTNSFGQSTTANTFGQSTAANTFGQSTAANTFGQSTAANTFGQPSNTFGQSTPSNTFGQSAPSNTFGQSTPSNTFGQSTPSNTFGQSAPSNTFGQSAPSNTFGPSTSTNVFGQPTPTNTFGQTGASPSFSFGANSGFSQSAPSQPFAFGANSQSSNPSANNSSSGASLFNQGASGTFNFSANKSGTAPVGRKIAPIKSRKGKIAEKLSAEPLSTRSFIKIDKRQNRAGNNNAGGNNVNLTGIKDGLTSLLTELNKLVAARGCFSFKRGNTKTYIITDDFRIRLTQIGAQLATLELVNQQRQVIPYPQGFAIRDNLYNEDVHKAGGVYVITWNASYTVSVKSIPRARLFNQRQVAVFKAHEGADGRVIADEPALEEDNVEEANVANQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2M2</accession>
    <name>A0AAD5U2M2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000535">
        <property type="protein sequence ID" value="KAJ3215561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2M2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="356" mass="40681" checksum="DD77EEA89AFDC31C" modified="2024-05-29" version="1">MVGQQTCKWVSMNKARGTCSTQFKHKGQLRDHLICKIQLRNRQQLNFHKKNPCEPKVLSDNESIPFSSPPSSPCDSEEILVDLNNWGKSSDSKLLEISNSLEVFNGLDLNRGMIEMEKIKSQNNNFLRKLSDGIYVPTQKKIDFEGLTFDIIEELSRHLQLKVSQILTQVIYNSPPVSGIQYLPPRRLSPNLNNFSLIKQFLVIIVKTVSKFIIETLSSEQQFNITYLEPVEQNTLLFKSNLDCTGASLVLHYNPINNINSKYAKLFIFNLVKILKTEVDTLVKKFIYGANSEECKKTCCFGLICGEQRFNLEVFEDPISLNAFDIVFRLGSDEDFVFLHAFDGNPLSFTNVNLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2W2</accession>
    <name>A0AAD5U2W2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 58 central coiled coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_002205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000171">
        <property type="protein sequence ID" value="KAJ3222532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2W2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049270">
        <property type="entry name" value="CFAP58_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083:SF34">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21771">
        <property type="entry name" value="CFAP58_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cilia- and flagella-associated protein 58 central coiled coil" evidence="4">
        <location>
            <begin position="463"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="789"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="996"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="131"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="438"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="501"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="585"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="669"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="938"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="792"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3222532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1040" mass="122163" checksum="11BCBCCD6991D419" modified="2024-05-29" version="1">MDNDAKDGKSTHNAKEVTIKIDEEKNEAPTNNKLSNSAGPNSRQPSAMGNSSLQIDKIVNKLKNFTEITEEPIEEEEEIFFGALFQLDHSPAFKFLEQRRQRKELTEKRMNELKGYIKNLHSFLLNSNTFEKKLAKKVKQVQQEVANQRMEIDRCGTKTFSDNTSIGELKRELLKIENEERLAMDREAKLQKDLEESQIQKADLNSEIDEIRKHKADMLEPQLIATTKELKLDVIQRRNQVENLEKDLEEKDSTLEMCTKEKDRLEIERDKLAIAISKASEMPLKILKQCEVLRNAISSLVSENSKQTTLSLQLDKEIERLAKKKIEFEERKLDQAAEFEQRRAEIHEMEKQCDEIFKQHELAKEHLSSLKAEKVKHELQIRHLIHQMKREHDILLRSLRDKESQLKLCRKLEMTVNNMYIYITWQKLLTRFFRHMSTEVLENQKEETKRHVQAAKREELRLRKEITDIRKKIDLSLYSFLKQEQMEKLEFEKVHQFFTVNQKLELELEELTKTFAALEKEIMQSKAERELKSRNVIRISQKYSFIKDEIAMTDIAIFDYSKRCGEAVQRLKDFATMYDVVKNERNKYMNQIQTTMQRAAEMKEKIRILSNEIEILRHEIMNKDRELQKKKQENDAAYSQRDGCKNEANKSLSLYREKRDQIGQHLSKIDTLNMVINGAEEDMINLKQRFALAAKERNEVGMHLLDRNDELCILYEKLNIQVMTLNKGQEELNNREDERRKYEIIRMEVSREVELLKTLRPKVNVVNCKLEKCQKELTETRSRMLELSAKMESPDDRKRSRYLGGEDPKKMNLTQKIQSLEEMLAEKEEKLLEKDLILAEISTMTKRLKQQTVKGRPESNEVALQLNDLAKRIRAVTRSMMGKVSELSMHQALTLSLYQQKTEKETLIQNAKTLLNSNKNGNQNGSSVSLFKNNCWESVELEIKKNEKQKLRRELELRNLMDKKSKEIAQASGQYVDLDEDGFFILDKLKTTAEPRPNAYLPEDAGLPIPKPYGSQAPFKPSDNVMLRHYRKPVIKPIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3C1</accession>
    <name>A0AAD5U3C1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NDT80 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003482</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000228">
        <property type="protein sequence ID" value="KAJ3221472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3C1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="361"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="361"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="475"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="671"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="482"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="773" mass="86565" checksum="5722B57436201DAD" modified="2024-05-29" version="1">MPTLNYSSDDDFDFVENGEHKVDTITPPTDEPDEVDSIEIIQEVTQVAEVNDINASGADLGAGNTAEILEVPLPKLSTDTIATDEIGIIDDVESSDLKSTSSIVEATPTSETPLIAKANFINLFHIRNKACLISWNYNYSKSQQVTSLKLLLSFISGVVLVLLNSIISTNDLAENVTEPAFTGFRTAHRFCFVKFQGSCINDRNFLVDVPQVQDKGLDDGCSLPYQRFFKISCINNRRTFENVNMGESWFGSKRLENFFHSLTEKTLKQNFDETLVAVNTGLELLKTKKDLLLKEFCKKEVTNDNGKVTGPHKNNDPQLHKKGCQFFLTKSLKDTFNSTDSEILEDVKRILIEKKKRLRVKIRKGKQYVRENLKGPQIIPTPKVCKSSGDPSIHFSNSSSHSNLHNLNELNNPSVITFERCQFKSATVTPNGKRRTIAVQQFFVLVAELYAILDDGTMIKVALSESSPLVVRGRSPGHYTDNHNNNVTNSLTPTSEISSTSTSNNSNPSPIIATHSTTPTNASLSEQIQQYNHLKGGHQEQLPNFNENNQGNNLTAVSPPLVTYGINGGNISSTTSNNNLHAPANSENVMKKTKLHHIDNHINGSNFLNGENISQIYQKQDYSTHQASRFGYSEVVTNNLQQQDRWVNNTTQFHSRHDDFYKRYENQDQITHNNWSQPDQPLHINGSSSSTPPLEKYQQLSLQDGNNGAFITSITPNFNNFNENGISNYTNSINEYPVGRSVVNVDVNGNERENYNFVTGWVCTKQIFFLFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3H0</accession>
    <name>A0AAD5U3H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_004634</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000332">
        <property type="protein sequence ID" value="KAJ3219653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3H0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF82">
        <property type="entry name" value="NIPA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3219653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="54803" checksum="8C4E47ACA0C990EC" modified="2024-05-29" version="1" fragment="single">LASLGINLQASALVSIRERNSLAELESQEEDSDSEINSNCDDEESVFNILQSGIHLRSNSICHTPELRDSQASEARIQKILDLNESPYNTKQFNIPPELSLNLDVFSSSQLDRDQLCLIREGNISQSDSEIRSKKKSDFSIENRWKLFFFQWQWYLGFLLYLLCQLLGSVTALNFIPPEIVAPLGATGLIFNMLFSKAFLGTSIIRKDWVGTLLIVIGCAIVSVSGSNNSGDVNEKKTIEDIISVYSKPQFIIYFIIQSSAVIFMFCFVKYLEYGGPLKRSHESENITFEDSQSRISFSIPHEQLEEAQDCINQEASENSPLLVSSQDSRKRLFRRKSSLSNTTSNRVSRWLRRKKRSFKLVGLIGTLYSIIGGIAASDTLILANNGLIVNSSGEKKNGEELSGEFGFILCGLVLIVMGVWLLGSKAEASTDDVEDEAKKIKKKKEKIEDNLNCSDNSNNSAKSVLENGSHLIEVEEEDQLQQQQENFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3P4</accession>
    <name>A0AAD5U3P4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000131">
        <property type="protein sequence ID" value="KAJ3223410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="171"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="368"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="480"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="590"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="791"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="955"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1218"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1355"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1547"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1634"/>
            <end position="1760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1819" mass="211121" checksum="0CC46E5D4797D6ED" modified="2024-05-29" version="1">MLTMELKSLLNSQESEINNYLKENSYLNQKNREFEENFYLAIDELEKLKRMNERYKEENELMLEDQKESAQKAIAVLIEKKDLILINDENMEKVEALSKENAKLCLNLEEACKEKKLVEESFLSLNSKFDVTLNELQEKTNFLVEVEGKNVNLCAEIESSRKELESVNFKVSEFAEKNSRLQAENNKLLSEITEKAEECQILKDENSELTKKLKLESENQSKALKGLQENFESKWSDKLDEIKNLEQKNEEYKNAISKLNDGESIFQQKIKQLTAELENSKTIYDDLTSDNNSLKLENAAILKKNDTAETKLKLNLNELEKCKSVSMELKNKNYKINFNNGQLNNDLDLLREEICKRNEMHERLVKEKGEVDFEKQNLETRVKCLEEQLVMRNGSISDLHQQVVQLEKEIQENDTKFQYISKEISRKNEEIIAKDELICDYKLNISRYLERIGVLESNIEKTASDVINTNEGLKIRFEERKAFELEIANLNSELLTREKEIGRLKNSNASLNRDLESYLEENDILQEKINLLSTKLQDNENAKNSLNNLLEEYVSKSKKREENETQLKAEAEKQLLDCEQVYLKLLVESNGELVQKISLLEEEIDTLQHEKKHLTLQIGDLMNDLCSSNSLLAEKENNFKDTTDSAKLRISELQNEKDELSKSIFELNEKVELLKKEKGDMETEYFTINKEVMELKEQLSESTQKNSEISAEINAMMLKNQAESNAGRENLESLNQTVEDLRSCNNALSSKVESLTLKSQENDVLKMKFAKLEKDFDTVSVEKANLIKDLETKHFMELNSVQQNLERLNEELVKSQLSYQDLKNEFNNLQSLNSTEIQRLLGELKLMTEQVNLLESENKNLLDELNTLKASQLQVYFMLMMYCHANNAKEKNISSNEVNNLAAQLELIESEKGLLLANIDSLNSQLFVEREHWTTSKVEMEEKLSFLESKNCDILTKNENQKVEYETVIQELNQLKSESKASVREMHILEEELIMLKLSKAEAETDFKNKIQVISSQLDEAKEAKLQADVELNSKNRELKKLREEIENLSKLMDVLKSSGSDSEKLDQKLKLLEQQLASKEQETCCLESKLKTEGNIKKKMEIYHKTLKESIKNSEEEIAGLKTSNTLLEEKLANEISYIQNNNAELKAEVVEKESAFVLLTESYDELYSQNSKLIKENEDLEFFKMKNEASIPDLKAKVDLLQSEIKSLNGIIIDHVNCLNQKNVLLEEKAAELNKANDAFNEHVSNLEAKLSNNLKNLEDEILEKSKEMHTEKKSVEICNAEILQLKNLLDDKDKDLLKEAESVRELQSKLDKNVIEVEELKNLLAARDLEINEKKNLIADFELNSFQKKSLLEDLETINERRISEIGSLEEKLIQKDEAEKTLKESYRKLELNLGTLQLELEKEKDKTHSVAEKQFEVIDELKKKLSAVENENFLLTESIKTFITDKDASKLELTQITARNALRSAEEQEKVLQFIDSKLSDILGIPIERNSAENLTKSHIEAKLNSLTELRESFCSKVLNLQQQMLDEKKIWEDIFKKYEKKCNSWNQGLNDVKLNVKELKREKSNLKKEKFLLNKENAELKMEISEKEKAISEQKSQFLILKNKFKETSAKISNSGGGLITSDDVIYIREENLKQVKNYELEISTLKNQALIEKEGAEERVKELLKENRELINKNELCKRKINFLEEIRKNSLPELSNNSFHNDSHLLQNEKLKQDLTQRDMKLQQLESKIEQFTKQATKLIKESEKLKQQLKRRDKLSNFVNNTITQFQGLYLRKDKINEALFNEKAQMLHMNFVKYGEKLNQDILKSAIEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3T3</accession>
    <name>A0AAD5U3T3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_001370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000138">
        <property type="protein sequence ID" value="KAJ3223235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3T3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08024">
        <property type="entry name" value="GH16_CCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057688">
        <property type="entry name" value="DUF7928"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408">
        <property type="entry name" value="CHROMOSOME 15, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35408:SF2">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25550">
        <property type="entry name" value="DUF7928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="617"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="660"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1044"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1079"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1124"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="72"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1156" mass="132362" checksum="F4257660B705DB72" modified="2024-05-29" version="1">MNETSSLSSQSSIRSTATMQNRRKVESKENEEKRRLEMRKWRQERQNDPALRWLKLMPLFGIIPSIVIVGIIIWRGIADLPKNNFCLKFQDDFDTFNLDIWKHEIQVGGFGNGEFDMTVNSRENSYVKDGILHLVPTLTSEKIGEKQIFNNFTVNLIGQGCTGDTFEKCVRTSNSTNSSVIPPIQSVRINTKNTVSLKYGKVEIRAKMPKGDWIWPAIWMLPKDSKYGPWPLSGEIDIMESRGNSRGYVLGGNEKFSSGLHWGPNPGLDRYLMTTTQYSKRLSSYSEDFHTFGLEWTEKYILTWVDSPTRVVAYTAFDKPFFKRGYFPQYFGFNMSTVVDPWSQTGNPATPFDEEFFLVLNVAVGGTNGYFLDGSNGKPWVDKAPSAESDFIKAKDTWLPTWDKNPDNRGMSIDWIKVWDKYLNMDSSSLELRNLRSRRKSINVIPYRYQLMLDRLYTQCVSEGVIPKDDTESCVVLKTDSNKYAIYPSNRDNELVNLLSGFNVEVAILVKSLNTEAILDLIPIGNDYVELLDNSTVQVLPSLSMLHRARKHQWGSLFRQEGVLVIWSEHVDDIIEKTIKYEKSIFDIVAQGLDQAIDLTYKEFDVEKISLEKKRPYVFVTSIISTLAMSLMVILFGLGAKTLVIVSMIDNYWQRLCLMLLLPLQLLFTSFVPVACVSSIFQIVGPIKQISQNSVYYSGKPPKRSEDLQLAHITIQIAVYTEGLHSVIDPTIKSLKAAMSTYERQGGTSNIFINDDGMQVISKEDALERQDYYRNHSIGWVSRPKHNKIMENGEKFIRAGRFKKASNLNYCLRVAKSIDDGIKFDGLTYEESFINAVKSEVGCQAGGEITIGDIILQLDADTRVPEDCFLDAVSEMNESPEVAILQHQAAPMLVAFNYWENGIAHFTKMIYFAIRYICGSGETSPFVGHNAFLRWSAMNEVVFQNEQGQYCYWSESHVSEDFDMSLRLQVNGFIVRYITYCGDGFQEGVSLTVDDEVKRWQKYAYGCSELMFHPLKYWLTRGPFTKLFRNFIFSNMNLYSKFNILGYIGSYYAIGAAWIMTLINYWITGYFMEELDAYYLISFNVLVTTLFVFTFLSTLAFTIFRYRTSSTTFFAGLWENVSWLPFYAVFFSGISYHVSVALVSHLVGYDMQWSVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U448</accession>
    <name>A0AAD5U448_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000114">
        <property type="protein sequence ID" value="KAJ3223872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1152"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1251"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1079"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1123"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3223872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1985" mass="226888" checksum="1656DBEACDDA67B2" modified="2024-05-29" version="1">MDANVKIAAEEKISNKDINEVLVKYGSDYIDEVIVPSAVVPSNSDYNFSSIFQPIPATSDSVSSDNENMLQSNSEHNSLSQAEVSPSKDCESSQLTLANLKIATELKVKTPVEEFSYNTNIDNSQLHGDLNFSQEIGQFEESVSESIPVLNQQLLPLSNEIKTEFDNQNPSVDNAVVENHEYVKELEVDKIFHFEKIDQSTNFADLDVVGKNVETKLDITLPLENKSMETSDTLKEKDSAKHLVSQEEVTSSSNINTQEHCEVENCVKEKSETELTEKQPYIQSSNKILENGNYQKKLDLENSISTPNFNSSTELTIYSASNTKPDFLNETVNISNSNIIDKFSYYRNTDAKSKQEGLNKHVDAAYNSSNGKEITLISKENIEEIVGTKNMGNDLEYDEYIKKAGGEKTNEDIQKICFVNDKNEKDGIEKSYTDILTIDDDGEKKIEDQAACHTENTSENKNNLKIDEETVQDSHLENNDHSNIVDAKSKLYYAENRNPAYGDGKYIIENTERKNEDLNDLNKEENKCYADSSLNMIKNNNSDDEKRCQAIKCLEDTYSIETGNERKCNFSDSNFISTLVDDVKDGKDNREQREMSTYFTGDTVKNNLKNTENSYTSNIPIITRTVSLISEEFSFSNSDKMKNSPMTPQLKSFARISTVDEFILFNETEAIKLEQETLDVKLEELMATNLEGQKQNKMLNLKKEPVWFKLFLKNQSRIVVLDERRDFDYFVDKVMSIFFGLNFEKDYQRFPLKTSKIVAPVNKLGLKVLGEGRELKMYYISVTGEKVTLDSNEALLKATDMLLQDPNLSFIPVFCSVVEEDGTEVKDIITAYGTPVAPPPINLKKMLELIEIVHKNPTNDNASTKVNASASDAEHLEHFVTTLANLSGISGSNPQNYHSDTITTIKQNENFPNLKETKYLDALNKETKNKSKFSEFTYKTEIKTKNLQSGSQNAIDFEYPFPGDKHIKTETIIKRPSTQSCKENFSQQYQDSVVEKANFNSMESNFGEGNKFVDKKIDKITIKTSKDMPKNINPRTKVPKNNVIKSKNLSNTEVTIARKDIVSHRSPPNIQDDNDSAESEVKLQSDVEFEKMDEEEVDSETSLSSLSTNCEDSDNSFSNYEPIKSRKGTEELSVHRSRKIKISKIQSKKIESVSKNDMLSRKQKKDRKFSESNSKLKDNSKLKRELGNSHSIFSENCTEIDLENESLEFQKNESKDLKKEEYATKNSSGLEKKSKLPKPVKNILALMNEDAKTEKGSKNINGAPSQDESLIDDTCNSQPKKKIADKNLKMPTADKKPSEIELDYSRLVKVSSSSEKFRKYKTFSADGKNSKTLINFIEKKHYGNISKVDPQKFDQNSNYYLEKKIIKDSHKVGVKKVDEFDVGDGWDNSVKIIRIKVYSPSILNEKRNCDTMESTNEKNCMTCFNKFNHSLSKNSENGAVEDHGNKDGWNCLQCVENLKSPQNDNEEVIDKEMILEKNREQSIKKKESAILKPKKLNSNVEAIQSQIEKKKTDKIQYKNYLKSGRENKVEVALSNSINGNCKSKPFNKDKIFQKNKNLKSSSNQEVRKHQTEKFQLEAEIPVDFEVFPENIYSDSIKISNLGDSQRNQNFLKKEQLCHRILQSDNYKIPCNITKQSPDIEETHEAYRNLVFPTKADPIKNQYDKYLQGRKIADHELPVGKKNFVKIEELNEDSTYYRNLENKKFKKIKNSKVISKTIFDDTLRLKEGKLKVSNQLNSLTNQKLVLSDTVNHSLLNNLNLYQQKMLEQQNLQLQLLQQQQFFKQKCLEQQIFVDNISNQISAYYQVKCDKLPAANYSTMLPADTVKSKKNGNPPYNFYNVKEFQNSNFIETYHHPTSFRQHQGNQHQNLCQYTNYSQNGNVYHQPIFYCNERKMYYDIYDYHQYANLFHPNINFGQKLPLEPINQSNAMQSTLINTYPVLKPITESQNRQLDGSIKKSQTLSCGLVQVIKNGTNAMALYSPSHLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4D1</accession>
    <name>A0AAD5U4D1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="2 6">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_003851</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 6">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="2 6"/>
    <dbReference type="EMBL" id="JADGJW010000259">
        <property type="protein sequence ID" value="KAJ3220982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4D1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00975">
        <property type="entry name" value="NMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00976">
        <property type="entry name" value="NMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="8">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="9">
        <location>
            <begin position="73"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3220982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="283" mass="33707" checksum="7D2A413BA1EDF3E2" modified="2024-05-29" version="1">MYSEQQIVEINFLCVHKKLRQKRLAPVLIKEITRRVNLFEIFQAVYTAGCYLPKPLCTSRYYHRNLNPKKLIDVGFSYLPRDTTMARQIKNYQVPKETFIKGFRKMEMKDCKQVLKLLNDYFKMKNLEFYPVFTLGDIKHWFLPIENVVYTYVVENPKTHLIDQFVSFYNLPSSIIKHPVHKILNAAYLFYYVPKKFDENESPREGEEDISIWEGKYLKELMKDALISAKLADFDVFNCLDILDNHLFLDELKFGRGDGSLHYYMYNYRCRNVLPEKLGLVML</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4E7</accession>
    <name>A0AAD5U4E7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial</fullName>
            <shortName evidence="7">Glu-AdT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000552</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000113">
        <property type="protein sequence ID" value="KAJ3223891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4E7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF7">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="6"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="437" mass="47163" checksum="03730FEEC941E1B7" modified="2024-05-29" version="1">MPIAVKGNISTVNLPTTCSSNILRDWVSPYDASVVKLLKDAGAIIIGKSNMDEFGMGAYGPTYNPVSFLNNSTNTDSLKNETSNRDLDTPTDDMFVPGGSSGGSAAAVAANFCLSALGSDTGGSVRLPASYCGVYGFKPSYGRFSRYGLVSYASSLDTIGILGNNLENTKTLYDLISSFDPNDATSVDFSSQSCSQERKDLEGITIGIPQEYYVDGLSQEMLECWSNGIKKLENSKAKIVKVSLPNTVNALSSYYCIASAEASSNLARFDGIRFGKRSEQPDLTEKHPLYSHTRTEGFGPEVQKRIMLGTFVLEASSYESYFGKATMIRNMIKEEFRTCFQKADILLTPATIGGAPTVSGIKINSNLEGGVSEYANDVFTVPASLAGLPALVVPFGAKKTTFNNRELQLPLGLQLISEFGNDELCFDVARFFNKTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4H3</accession>
    <name>A0AAD5U4H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S14, S11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS14_1</name>
        <name evidence="6" type="ORF">HK099_000122</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000101">
        <property type="protein sequence ID" value="KAJ3224200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4H3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000002">
        <property type="entry name" value="40S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="149" mass="15958" checksum="040EF2132BA8618D" modified="2024-05-29" version="1">MPPKKAPKVEKENITLGPQVREGQNVFGVCHIFASFNDTFVHVTDLTGRETIVRVTGGMKVKADRDESSPYAAMLAAQDVAVRCKELGVNALHIKIRATGGNGTKTPGPGGQAALRALARAGMKIGRIEDVTPVPTDSTRRKGGRRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4K0</accession>
    <name>A0AAD5U4K0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bulb-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000284</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="entry name" value="Bulb-type lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041957644" description="Bulb-type lectin domain-containing protein" evidence="2">
        <location>
            <begin position="16"/>
            <end position="2040"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="3">
        <location>
            <begin position="823"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="791"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1855"/>
            <end position="1878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1942"/>
            <end position="1974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="791"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1954"/>
            <end position="1966"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2040" mass="223854" checksum="885707883F82FDF9" modified="2024-05-29" version="1">MRFLLLLSLIAYVLTEMGGGWGDTGRDAQEAAANANKNSQSSLPSVNPQQAVDCVEKLKKLAKDKGLAKTKKKRSYSDNLHRKFIDEPYKKFGKREGNEPVTGFGKCLPLVSISPAANPYHDLLTGMKYEQIVSRKGFGPSMRLSEHSIDCTADTQPCPIALSQSITITTSLALSITTSSSNSKTFTNVTNWSQSASDSITKSITDSLDVSTNHQTSMEDRGSFAENVQSTLTKTHEESTSNTHTTSNERSIQNVKTWDHEEGRTENHEDGTEGSTTTGTDVTIGTNWETGKDGSTTTGTNIEDGWNKNTAKTTGVDKTDGWENGSDTDHSDENQESITGECSFSLSKESSIQGSVSGGLFGIGLSVTSTSSTTKGDTVSMSFTIGKTVRDGKTTRNSTSGSTLTHGSREDSDGTTHSTTTLNSITNGHHENQGGSQSTNYIDTTVVGHHRTNSYGRSWIDRTGGSESITNGHTESDSKETRIGDSLSEALTKGSTYEKGWSRGTTDSYGLSNSHTNGLSNEKGIVDNRGGEYSNANQMTTSTESQRTDTVTLSKTNEITFTDYVKPGTCGFLVCKPQVISVAVPWLCRTGPDSFDLVTTEVQEIQSFEIHGIDGQIRRAPDCTIKVDPCHEEPIDFLIGNQDYKFDPTKAIASGQYFTPESNPMRPTADGYLISFDQNNIFCVMHYDEIVWSTHTRPSGKTRVRITSEGHLIQESTNVYGDESIWSTIWSTIPNHLFHPVGIYGKVGYKLFLGKNGELELLDSSYVKIWSSNRRVSKNALGFKYPQTVTLPTTNPTEPNEPGQVDPHNDLPTDIIWRGSSLERNGDNCTMINEGEGLMSPNKRFKLYLTPRGNLIFKDGTRTMWESSTSSLWFAKDGGYKAYIGSDGSFQVKDTQDRLIWKTGSLTNGNKFSVEDNGNLVLYDKDKIVWNLINIDTNNLYPTIMTYYDFPVISIDTCRVAPIQLSIAPLVNILTGKCLNYNSTNSIGYYVMNRTYVRMKGCDPWTYNPARFSYTPFTEDDWHSKCLDGKNSTVKDCDKNNAWHHYSDGFLTGLNYQNLCLALNGSATRCDGNGIRVDKLWTHGPSIKESLNINDKMIMMGHVIYRNSTTVSINKYGDILFKHYPSGTIEKTFKIPGIATPVTPGPIVELRNDGSLVLTNVNDKILHTYVSGGRGTPPYRFGPKSPVVSVLSSLDNPKGSLDPEILARIKQLIGDAVPDFLPDALPTTPRPTAQASSTKYSEIKRAIQEFAKYKLSLNPDTRLNDDSIRNMERVGNMIYLNRVTDGYNIRMNEVGRFLDSLSEAGNPHGIVATYVLEPVAGLPGLRRIPILAFSQAQGNNVAANVVNEDGLSIADALDALVNNLFPDLGVTDDRTSFVLPLRVSQNAFKNKVPLKLIRFADTAVGYNIVVDQERASPTLVNQARNLVASRNEGVDLDTLSNEIYVAFLEVALGAVRAVFGPGGPNPTGEQQPIFQDIANMLTEHITARINGLNGNTNPEDPHVIVANALRELGLQAATLYGDCGGARRRKRGLCGVMNGLEDELDLSQGWSKAIKGNNNKKILLRGIFRQPLKDDEVNEMANRMLDSDMVDEDIISEEKNSNKLKGCSTKPCNRKNAKGLSSNLRNALAKLQARGDGKVNPATNFKNPSQDFIGEDIVKDAGDGKYGISIAINSLADSYTASDVKYAIGDIAAELDSVEANNDNFMEMDAVLNFHNTFATSPKGFAKLKNKLNTKQAFISHLQNIKDKTGTTNLDKYINNKDTSPESMQAAQDALQEYSDIDVRDTHASFIIANRIDLHQNIDGNSPNDVGHADIEASNYNDMNPGNEIYHGNDVLSSNARSSLLLHDTLRTYKSDTGDSDVLGNPDAKPDADGNYSPQDLIKGANNIGKVYDMLANKLSGMKIRNAFSRIKWNRIKNNIKKIVGESKRYLEKQPEVHIDDVANHNKLSNQSKNLDKRPVDTKGTEGKTISGMDTGSAVYSQKTIPKSSDSVDQPADIKIDNSKIKTGNVKNRFSSSKLFGKLLRNAMNNKVMHSGKGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4V3</accession>
    <name>A0AAD5U4V3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_008540</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000095">
        <property type="protein sequence ID" value="KAJ3224368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4V3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF77">
        <property type="entry name" value="8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="33"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3224368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="332" mass="37153" checksum="B90C8B2D3E758A75" modified="2024-05-29" version="1">MDSSRELRLSLKNKLKLRNDRSMLRILKSNTHLADFSSNDYLGLAKNESLMNNIKLASANILQNGSTGSRLLTGHSQHAEDLEFFLAQFHKSEDALLFNSGFDANYGLFSCIMTEKDGIIYDELIHASVHEGMRASKSKYQKSFQHNDVESLITQIQEFKKINNDGHLFIAVESIYSMDGHVSKLEEMINAVKNYKNCHFIVDEAHSTGILGPQGRGLVSELKLESQVLARVHTFGKALGSHGEKFRGSLCDLPNGILLESDTPIQGVLVPERYQLDVRPIRSPTVPKGEERIRICLHSHNTDSEIDLLTNSIKTLILNSYVSNTNAISARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U568</accession>
    <name>A0AAD5U568_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_007898</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000081">
        <property type="protein sequence ID" value="KAJ3224779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U568"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010828">
        <property type="term" value="P:positive regulation of D-glucose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090314">
        <property type="term" value="P:positive regulation of protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031340">
        <property type="term" value="P:positive regulation of vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08688">
        <property type="entry name" value="C2_KIAA0528-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037785">
        <property type="entry name" value="C2_C2CD5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038983">
        <property type="entry name" value="C2CD5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056431">
        <property type="entry name" value="C2CD5_YbjQ-rel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412:SF2">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23025">
        <property type="entry name" value="YbjQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="C2" evidence="11">
        <location>
            <begin position="765"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1217"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1218"/>
            <end position="1227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3224779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1267" mass="143221" checksum="21B796A739131F9B" modified="2024-05-29" version="1">METEKVQKLKELRDELALLPNKDSRATALQDEIISLAQEIRATNMDLNSSSGIIDESDLPSPTTLLLPEDYPKIFRNPQKLYAHPEDYLSDKEPITPQLFLYKDGPRSRLFLRISLKINDGFTAATFLLDTGACPHMYISSQLKELIRKRIMMDDAGSDFIKCKVGEDEINLVIKEDLPKIHQPANVMGLPMLFLMGLNLKQGRTSSFVYSDDGVADDVAPVQKDNAQAIYKPKSLYTIIFRLFYNDFRNFTSRKTCMTKNEKLTPTSTTVSSSITPQTFYNIARLPNKQTVIYSTKKSAIYNLEGCKEATLRLSYFKNDINEDLSKIKKNILIIKKPKNPKTDQAFRDLVSFLHSTYSNVNVLVEEKVFNKFFNEFNFLKTIFHHQKSDTFERVTDLIITLGGDASEMFPKECPPIISFSLGSLGFLLPFKFINFKTVLKNILTGKSNINILLRQRLNLTLGDNNNKSKDNNSKSFISMNEITLHRGSKPHLTTLKVSVNEQFLTDAVSDGLIISSATGSTAYNLSSGGPIVTLLLPSDCNIKLQVSQSSRIGCEVSVDGKNVGEINDGEEIVVTESDFPLPMVERETEGWIGDLNKILKWNIGFDNSNNGMKMDGMNVKVTSNDIAEANTIGTQLFWATSFLIMCLIERYSNYIQLKKESEAEKLIPTYIPIQEFLQKNKNEIEDFQKPHSFQINQNLTSSSYNDTVVENVNNVDATLEVNKNREVLIKTFLWTFNLALKYFIMLGIMSFNPLYFVFIIFGQSFGFYLTELRINGLIKMPCILKVRITSARDLPIMDRATEAADAFVEVKFADFEPKRTQIAKRTLNPIWNEDFRFDVSDDSDLQNEPLEIKILDHDTITYNDVIGTVFVDLNSLLSWDSCSEIKGWFPIFDTLRGIRGELNAQVKLQYFGDINPFKDSSTSVQFFSINSIPSTYQAVSLLGFVSALDSADDPEYHWSDNFRTPRTSNEARTRLMYQLSGQLRRQLGKRVLEMGGNAVVGYKQFFDLESEEHMIIARAIGTAVKLGIDNSIELNTSTLSQKWNLMQSPVLSPTALHTLESTFPPITSPLFTPFKTDNDQAGNASPTDQQHISTLDLDIAGRIEKPIQILTLDTFASACILGSGGFVSAVSVKLIENDDKELRITWWNELRDEIKSHAKQLNCNYILGYTETITIEDELCVLQCSGTATVCDMSLFEAETTSRKLSTGNKSHFYGTESKKNSKDDFDVNPPNAMESDVEKNIEEDKDEDYNVRKSVFSSSKDYQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5I2</accession>
    <name>A0AAD5U5I2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7918 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000070">
        <property type="protein sequence ID" value="KAJ3225134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5I2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057678">
        <property type="entry name" value="DUF7918"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25534">
        <property type="entry name" value="DUF7918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7918" evidence="2">
        <location>
            <begin position="9"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="37595" checksum="B36DFD12C2CA0579" modified="2024-05-29" version="1">MPITAWGSIHLIVDNKELNEHRTTVSEDGKQVHCWIEATEGKTYQIKASTLPFFKASIHVFVDGQWNEGRILSGGLVGILQGRTVGENQTQPFIFSKAKSYKSIFNHFNLLIIKRIDNVESSKDENSYNRAGSITVELWHVEIVGKLEFSWKPTFGTCKYEGLKFPFSYYKVEDKRVGSSVMITRPIFSEPFLVVTFEYLSKELLLKKGLFQIPESISEPNFSYLNNTLTKDNIGLIGDLTTEDLPSPSTQKIAKSASRKGDGVEPKQKKRKISKLNLNKTLNNDINESLTSTSKLIPVDPSLFSLETAVLPTNFLSHHPDTSRFTMHSANSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5J6</accession>
    <name>A0AAD5U5J6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000269">
        <property type="protein sequence ID" value="KAJ3220840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5J6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3220840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="346" mass="39968" checksum="D644EB5A472E939B" modified="2024-05-29" version="1">MTTLTHKTSFQKVFRGTQLHYDRLTDLLFQCNQLQLHTTHFSKYYLLNCPPAIQKSLHKDALEVITSELNKLDNTNHRGSGDRRALVDHFLPFISAYKNQINYQGEGVRYFQQLSTYMSETFETNIKDSDLEPGISDQSYLMDELFLLDADRTLIHQIQAFLPRNIHVNGIPRDITTRPEAYLNSYIALGRLFDQYGLRSFNAVPLSTSTVPRYLILDTNILLKQILGITQPTKINEETKPDIGLKAGFDVLLLDEYKTSKECPGCEGETVKTFKRRENPKPWRNNEVTVHGLLRWQSEKCQQSCGHPSRLWNRDDVATLNQRSIVESMLAGEFRPVRFQRANLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5V9</accession>
    <name>A0AAD5U5V9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-oxoacyl-ACP reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_006802</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000061">
        <property type="protein sequence ID" value="KAJ3225431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5V9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF17">
        <property type="entry name" value="RHAMNOLIPIDS BIOSYNTHESIS 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="26862" checksum="3EEE1BC43A0B4229" modified="2024-05-29" version="1">MNINKLFSVKDKVVLITGGSRGIGLMIGEACSSRSADVCDKVAKELNDKGPGKCFSIPADISKLSEVKRLVGEISKKERGINVLINNAGANWGESLDKYPDEAFEKVLNLNVKRVFSLTQACLPLLEKVATNSDPARVINIGSVDGIRTPALETYAYSTSKAALHHLSSHLASHLGSRNITCNAIAPGPFQSKMMKATLEKFEESIVSGIPLNRIGSPEDMAGVCLYLSSKAGAYVSGALIAVDGGSLVKARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U651</accession>
    <name>A0AAD5U651_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_006584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000058">
        <property type="protein sequence ID" value="KAJ3225550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U651"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037473">
        <property type="entry name" value="Lcp-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539:SF1">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37539">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic" evidence="1">
        <location>
            <begin position="148"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="275" mass="31641" checksum="B8FD410F96C47D07" modified="2024-05-29" version="1">MFQQSFPCNEQFQSPYYEPVIQFSKYHKTEMELEKLRLIGDEICEKAVTFIETIKNSDISNSNCPLKFRNTLNLMRAHIENESNPNLDVVDFLSGVSTIPEWVDFSQIERGQFSLIKYSFPTLCLSLLHSSLVGGVSSPKINAVLISTGYLSGSLTFQRLIETTHWLIDIMKPGSLVPGRKGWRSTISVRILHEKVRQTIKRKISRKDSAFDSDFPVSKRKKSNYDIQKYGVPINQEDMIATALSFFGIYFDTFPRRLGIVLQERELLDILAVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6G5</accession>
    <name>A0AAD5U6G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein 37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TTC37</name>
        <name evidence="4" type="ORF">HK099_005809</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000047">
        <property type="protein sequence ID" value="KAJ3225984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039226">
        <property type="entry name" value="Ski3/TTC37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704">
        <property type="entry name" value="SUPERKILLER 3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15704:SF7">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="643"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="904"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1476"/>
            <end position="1509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1666" mass="190036" checksum="319750AC16197EA5" modified="2024-05-29" version="1">MSSKSLLKSARECIEKKEFEAAKGFCEQVLENDPKNYNALVFLGLSETNLEEFEQAEKTYKKAINISPNMVIAYQGYITLLEKSNQLEKLIDVLLQTIELFFAANDGKKCLDFIIKLNANYEKLNDRKRIISGLNMFLPESRYFNLIKDQDNLENTTNILLKIAKLQEQEDQEHFAKEVRTRSMRLGSDTTANIKLAVEKEIILSSKLSLIYEDILKKSELSSSESTSFKQKLLEFYYKKIQYLPVGTEKNDLWEVILNLSKGLILENSNYTLAYKCLIYFNDDDFDILDHSIFEKAIETCDKDSDLYRMCRGFLIWKVDRNIEDSLKEFLAAIKNSPSLFSYKCLASIYTEIRDPESALNCVSRCDEELKIASDRTGTKEKILLIQAQSLLQLGRVQNSGTKNYLSQALGIFKIILLNNDNHGVGEALQVMGKFEDAAIQFEKVLQLDKNFFQCKKNLAWLRFLQGNYSKSLELLQEMIEVENLEKKLEADCLFQIGRVHWEISVENRTDKSRCLNYFLRSARLDPENPNTFNFLGKYYLEVENDHLRAIKCFQKSHLLIVEGKDLLQELENFQSPSHSLTNLYLNDRKIDLALEILDSIRKSNPRDYWSLKMLGVLKLDSHEYVAAISYLQSSLRINANDTTTWECLADSYFKEGKFLASLKAYNRVLELDCNNLYVKFQIALVHLKLGQFETACQNFKKILEINKLKEHLPTVRKMCDSYLLYVSENIEIGAYGHAAETINTGDLCSVSRLIPGYLNLISLETINNLKKVLFTFLREKEEPDFTIVCLDSLLTLSISSYKCCILFLKSNTSLDINFSETLAFYWSDVGLHYFWKYQLKKNKEVNEAKTHFEEAVKSLNVSLKLYPHSSVVWNNLGCILFYENLALSQHSFIRAIEFDSKNAAFWANLGLLYLKEKDFQLAHQAFGQSLFNDPENIASWFGKALISLLKNPNISMENTSVFEQFEHALDLGGAFPEINLNFAYQHYLHYTANNSDMLDSSSFNVPIFCLFKYIGRFLPVDNYPISVFNKKPVAVALNLLGLFQERQCMFQEAIYSFEKCLVVLNDSSIQSNDSLMFKVKENLARCLCGHGTFEKAVKIYRDITANIAVEKGVPEMCMGLSFFFNGDISESLKWFENSLKNASDIGGYVFDQIGVMISQVLYSLNKSNLGVVKQHLLSCVSRNSQNVNALLSLTALGLVGNDLNLATSGAAEIIKLAPDILNKANLEEDANFVLSRLFLQQGNKKISVGFFSKAIHTMPHRAERWSRLGKLMHQMHPNLSFSASLAARVSTLLPRSELSRSEIASMYTTFGVTLLSSGNGLKKDPVATDSQSNILKALRASPTDLESWFALALDLRSKICHITSKPYLYLNSAQKSDMALDLIKFKIKSVKDILNYIINKNKINNLIQECQTKKELAKKFKLTQIFYWSLQLECELTLLEATFVIDTKMKIEMCKLVVAKCEKIFGECSSSDIKASSLVIIGRGYKTIGDIKSAIGYLKQATSLLPNSSSLYEELGQLYTESKLFLAAEICYRAAIKLCNANKSSPLLRLAILALKQNNFSLSSEALNEASNLKEADIYTLKICKLLQGLLQFKSGNEGKALKTFHSILDLESSKENDQLSIPFLHYYLGVIYKSKNEIEKYDEEYELELKQFKNWDLVGKYLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6G8</accession>
    <name>A0AAD5U6G8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">2-oxoglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">2-oxoglutarate dehydrogenase complex component E1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">KGD1_2</name>
        <name evidence="19" type="ORF">HK099_005274</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 2-oxoglutarate + H(+) = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:20092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000040">
        <property type="protein sequence ID" value="KAJ3226277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1150:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12470:FF:000003">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase, E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <keyword evidence="17" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="18">
        <location>
            <begin position="643"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="1397"/>
            <end position="1438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3226277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1581" mass="179091" checksum="103782E143C5D954" modified="2024-05-29" version="1">MWKAVVNNGSYHKLKLSNATKFIINRNNINITIRRNSNFLNSTSSSYIDEMYSAWKKDPSQVHLSWQIYFKNLSNNENFVVPNPPTITSSSSQLLHSIGGDLMTYETTSSLPENANQAQIKDHMKVQLMVRAYQVRGHELADIDPLGIHRPNPAPELVYKHYGFTEADLDRSFQIGAGILPRFKKATENKTMTLREIIQALQNTYSKHIGVEYGHISDRAMCDWIRERIEVPTQFNYSKEKKLVILDRLIWSDSFERFVAQKYPSEKRFGLEGCESLIPGMKAMIDRSVELGIASINIGMPHRGRLNVLSNVVRKPNESIFSEFTGSLDNHVEGSGDVKYHLGMNYFRPTPSGKMVHLSLAANPSHLEAVDPVVMGKVRGLQFYQNDADTHNKAMGVLLHGDAAFSGQGVVYETLGMSDLPSYTTGGCIHIIANNQVGFTTDPRFSRSTPYCSDVAKTVNAPILHVNGDDVEAVVFALEFASEWRAKFKKDVVVDLVCYRKYGHNETDQPGFTQPLMYQKIKGMKPVANKYVEQLLSEGEVTLEEIEALKARIWDILEKNYEASKTYKANSAEWVSSTWPGFKSPAELAAVTVTTKPTGVSKELLKHIGRQTGVYPAEEFKVHSNLQKILKQRQESVLNEHGIDYATAEALAFGSLLTEGTHVRLSGQDVERGTFSHRHSVLHDQNSDALLVPLNNLVVPDLVPSQAHFSVSNSSLSEYGILGFELGYSFVSPNQLVMWEAQFGDFANTAQCIIDQFISCGEQKWLQRTGLTLLLPHGYDGQGPEHSSARIERFLQMCDEDPYLMPDPVGTEKKSYSRQHQDINMAIVYPSTPSNYFHVLRRQIHRDFRKPLIVFNSKALLRHPLAKSNLAEMEEGTRFQRLIPEVLHPNPLSTTSLSDEASELVGGSHWQRNNVETRIPYGLVKDPNYPLEASLPSIESSSSGSMDSGDFKLLPPNEIKTVIFCTGQVYYLLHRARTLNQLNHIAIVRIEQLCPFPFWEVQRVVDFYGNNLEEIVWCQEESFNAGAWQHVEPRFETSIRQTTWYNSQGAEKWRETLDNNRYAGGLENIRQANKLPKSVRGGRYIRYAGRDQSAAPATGIKKQHKFEEVTLVSEAFFNGDLKKPLDMGKMYSEEIQDLELVGEEEENVSSFFLEEPDEIQDINWSQQQVSRTFFRRNRILTYRTYKNLANLNNTGNSFNYETFCITKPVKNLYTYFSIKKTENKYSNHFQLRNLLWATSKNDVFIGVKYGIDHYCPKTGRIKNILDLQKEKLHQFKISSICAKSNILSCGGFYGEFAFKLLNSTENKLHSYNITKNVEGITNHIDIIQQLNQAVISSNDQKIRFFDFSSEKVCNSFSFDFPINCTGTSSDLKTICMVGDSVNSMLIDQTSGKIIHSLTGHTDYSFSCAFSPDNKYVTTGSQDLSTRIYDRRNLSAPLTVIRARIGAVRSLRFTEDSQFLAIAEPADFVHILDLNTWEKNSNLESKLSFFDDPINSMNSSSYGGGIWCCEGSKFIDNYEFLISDKATFCCQTIDFFGEIGGISFSDYHGDSLFIGNIDELYGGLIEFERNKTGKNLLNELYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6I5</accession>
    <name>A0AAD5U6I5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Restriction endonuclease type IV Mrr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005047</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000038">
        <property type="protein sequence ID" value="KAJ3226339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6I5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018828">
        <property type="entry name" value="RRG7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133:SF1">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction endonuclease type IV Mrr" evidence="3">
        <location>
            <begin position="12"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3226339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="229" mass="26370" checksum="A26B256D3CB73DF8" modified="2024-05-29" version="1">MLKKLSTVEVGTKFELATMSTLKKLNFDLRRIGGAGDNGVDLTGFWNLKKKLNFPVVVQCKREKKKIGTNYLRELEGVLSRRERKGSLGFLVSSEGFTSKSVTHFNSSILPLFLVHLKELQLKTSSQTKKDDFFENNETSYYISDFKMNKVAEDLIKDLKLNRGRRNKKAVLENQSKDICFDIFEDENFFEVVYNNKTIFVSNNIYKLDNETLKISTTNSVNSENEQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6J8</accession>
    <name>A0AAD5U6J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleosome assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000080">
        <property type="protein sequence ID" value="KAJ3224820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6J8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1500:FF:000001">
        <property type="entry name" value="Nucleosome assembly protein 1-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="226"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3224820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="30973" checksum="1ADA2B9C8D01BCCF" modified="2024-05-29" version="1">MSGPTQDPAMLAMLQHRLDSLAGQPSDYIKNLPENVQKRLRALKNLQDDHLNIENEFEAEVLALEKKYFNKYNPLYVKRQKIISGQYEPTDAESEREPEDEASIVEIKDEDALIKGIPEFWSTCLKNSPEFQELITEKDEEALKFLTDIRYSYLKEGMRTVPTDSFFNFFSPPTYPTDNEKDEEIDDAEDLEQRIEIDYENGEFLKEKLIPNAVYWFTGDAIEMDGYDFGDEGEFEDGDEDDDGDDDDDDDDDGAPGAEPAEKPECKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U740</accession>
    <name>A0AAD5U740_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Peroxidase mlt-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MLT-7_1</name>
        <name evidence="16" type="ORF">HK099_004082</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF4">
        <property type="entry name" value="CHORION PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042120848" evidence="13">
        <location>
            <begin position="19"/>
            <end position="2073"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="725"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="759"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="790"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="833"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="15">
        <location>
            <begin position="564"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="14">
        <location>
            <begin position="888"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3226813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2073" mass="235175" checksum="15DE68C2517956AA" modified="2024-05-29" version="1">MKNFFILLLCSHISTILSLQIPYKNSEIASYNCTGCNEEHPNYGASGEYNLWKTPPRLTDTDPESLVSNLSSARLLSNLLNNVQETSYTEKFISELLPQWGLQLHLDISLTNRNSSVSDDIKVPKGDLTFDPNGSGNETIPFSRTVRFGETNGKINLENTFTPFIDVSEIYGNGNYFGNKIEDVRLFKDGLLKSLHNETGEFPLVGNNEFIWSVPNTNVVPVRNIEIFEFTLIFKSSNIFATLFLREHNRKARNLKKCYNETWTDEEIFQKSRRWTIAVKQKITYEQYLPILLGSPLEQYVGYNSSVNPAIDTFFSTAAMRYGHSAVNTIIYRINENNSPYSGGHLLLRDVVYKNYADILRSGIEVYLRGAILQPEQVVDLNYVEDLRSSLPFNNPYGFDLLAVTLQRARDIGLCTYNEARKAFGLPVVTEWSDLTTNIELQEILKKEYKNVNNIEAFIGSKLLSSGLIENDGVGTIGPLFRASIGEQFTRIRDGDPYFYLSGILDEEDTQDLKRMTLGSLINLNTIIKNFPDNPFILETETVNTFSDNSRKATKIPYKVSFTMDYLLDWSVSEGSITFTVTTNYTTGWFAFGLGKTMNDMDIYFFTKNNGSWNILNAHSQFVGFVDFNEISNINNFKNINPESKDGPVSLQFSRPLVSSTISPTFKDIVNGTQYLSFAYNLNGYNLQYHGPSQRGNLEVDFLKLKQSIIEVVSVSVSSSRVNTLIMHGVLMFISFGFLYPAGIYVARYHTNLRTWLDIHQALMSIVTSNTVVIAITALVTNAFSGGLTAHSICGLVMIGTIVFVSLTGFMSFKISTRFTIKYTLFLRNIHKIIGFGMYFLGVGKGITNIYEIDFFLVVNGYLGCRDLAVLADLHEGLPLAYLLEENHQMVLIRQVRTYRNEINVRVESGAKWIIIYDTLYDVQKVFDRHPGGKSILLEVTGIDATNYFEGFQTGSKNSQLFHKHSRLARFMLEKLAVGKIALMDEEKSDLDLSRPTLIADEEKGFSKKLIFSEKFVKLYRTSIKKKFLTVEFYRDLESKTLLTEGNSKRPVYSFIFSFPDQNSTLKIKPGEYFNFRYITSTGAVITRSYCPINCINQGSIEFMIKMYDGDMTRHLLACNSINLRGPLSGVPLLCHETEDGCWDNLGLIAGGTGLTPCLQLINYHLLNSKRDATTNMLNSKIHLLNVNNTYNDIFAKQLLSDCIKKSGGSLQITQLLKVADHNYEGLVGDIDSEIVKATMPLSENKTCIVVSGPASFTNLVEKRMSELSLSPVSSTTQLTLLELYPKDEQLFSLLVKLKPIQQNFILKKKKKATVIGKVIGKIFKTNDKENFNNAVLPESQNFTEEEIQIVNLVKNLYFEMQQELEKLQDISDYGESDLPKKKSLQKRISLSPDQIQHHKISKTQTIKDVLNLIHRLEKIFNKFQNHLDLVDPLLVIYTATIEKYWNVTRKAHCSHWKFLPIIYIQPNSVTRQKICLQKHKVDERFDFRCVQINNKEVVAGTSEHPLHDFTLLKEIQTEKSKYQAVLTASYPYVQPTSTDPAMVLKEKVLVSDPNNDGYFVVVNKGIAVGATVDGSGSGFAPRLASNIILATVNQMIDELLNLLTPSTVTERSTQLDSNDDVRENNCKKTSVDSTLNSLSSHVIFQWLQKLIVKSHQNCKNVQEAGSTTASFFVILKLENKQHDFEYVCCFAVTGDVEVQLFQHKTKEWVSLLKEPTSTEKARIDTSSTPGGLGGHHGDQKRLYGMHFWSEEDWGRPTSQKATSPTIADIKQQPRRVSKSGLRCKGNNLHFGQVLLTREDIVLFSTDGLGDCIDPPQLFRTPNSAQAFANSIGIPFMEQVELKTTLDSILAMPDYTEPELDKRPAFKKEPDEVNLDPKENWLEFTRKIPEAAIKIKNLKQIILNIVLNENITYFNNNLYQPYDLFEESSDQSNSTENIKSDRTYNRTSQDFTNCNINYNSASRRRKERENNNSPVAIIEKLTEFAKFVTSGERELYESHHSYLKETTWGKKNILDTAKENFCVNNPSPSNVCEKTIEENKSKYMKLKYLKPFLVPFAKMDHIAIQVISPTIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7F9</accession>
    <name>A0AAD5U7F9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitogen-activated protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MPK1_1</name>
        <name evidence="7" type="ORF">HK099_000448</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000110">
        <property type="protein sequence ID" value="KAJ3223964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7F9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="277" mass="32083" checksum="526A783E9C25A8D7" modified="2024-05-29" version="1">MDIGADADKFNEMFMVLELMEADLHQIIRSEQPLTDSHYQYFIYQICRGLKYIHSANVLHRDLKPGNLLVNADCELKICDFGLARGFDTIGGDENNTGVMTEYVATRWYRAPEIMLSYRCYTKAIDMWSLGCIFAELISSKPLFKGRDYVDQLNQILGILGTPDDEVLKRIGSERAQMYIKSLPKMKKIPFETFFLDANPLALDLLEKLLKFDPAERITGEPIEEALEHPYLNSYHDVSDEPVCDKFFDFSFEKEDLSLEEMRKRIAQEVIDFKNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7G1</accession>
    <name>A0AAD5U7G1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7G1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="59" mass="6805" checksum="690130869DCBCF97" modified="2024-05-29" version="1">MLLHTRLWYWFKSVLVGPPSPMSFNGNPTNKKETRKKCWEGPLKKKDSTQAATIKVEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7J5</accession>
    <name>A0AAD5U7J5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000017">
        <property type="protein sequence ID" value="KAJ3227414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7J5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="487" mass="57564" checksum="5C365E4B1689E24E" modified="2024-05-29" version="1">MLSEVRINAQEKRNYLNSVKTSLEKEVISNSKNQSSLSLLRAFKKNLKNTILNDNNYEEKEKISILNHLDILLLSNLKTSINYNIDLYNRRKIFLQRNFSHKNKVFISNERLNKMNNELNTSWKEILKNLEARIDVNRLSLEEDLKKKKGELEIELNVLDAIITNDEQKMENTTDLFFKLKRNFFSATHDTYHNLMKGWINIDFAHFEKDCNFQIKKLQEIEKLKQDMILQGLKVLPDTLYYLVKAIFANRYSGDKDVSYDEINSLKTILKKFPPQTVPRDFEYISCLLEIMFLIKKEKESFVLLSHNLSVFKNFESFDESELSYGDDATKKNIAEKLKKNYDAFKKEKLIYLRFLKGLSFSKGGSRFSLNKYYYFLLNKEVLPNKNIKNAEVNIFEDEEEFNEYFLYCAYNMLVDGGYSFAWNLFENGKFDSNLFCLEVLCEIFVARNAKLGSFRRDFYLEKLNTKLRSFGLSFNVAKNMIENLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Z0</accession>
    <name>A0AAD5U7Z0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein root UVB sensitive/RUS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Z0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006968">
        <property type="entry name" value="RUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770:SF31">
        <property type="entry name" value="RUS FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12770">
        <property type="entry name" value="RUS1 FAMILY PROTEIN C16ORF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="6">
        <location>
            <begin position="106"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3227981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="274" mass="30582" checksum="836485149603EE35" modified="2024-05-29" version="1">MQHYRTLSNSLILKKASRYRCNSIIFLSSYKNLKKENNLNNQKFKSEINYKNLILLQNQNGKFGQEAAYSKVIEKDSKDNNLVEKLSTLSMQALLQSMGMGAGSAIGLASISNIGKNIGWLATSATRVSMNRGVTREDNLGDVTAKSGAQSTAAGLIGTGFGVVLSYFVGVEPLTLMAVFIPSTILNMYFAYKTNTSVVVKTFNLERGEICLREFCEKIVSSHFEKYNNVKKLEKNKLDFSIINSKKVEQNFLKFKNLLKDPSEVGNIKKKKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U852</accession>
    <name>A0AAD5U852_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Brefeldin A-inhibited guanine nucleotide-exchange protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ARFGEF2</name>
        <name evidence="9" type="ORF">HK099_001241</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000133">
        <property type="protein sequence ID" value="KAJ3223365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000003">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="8">
        <location>
            <begin position="813"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="277"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1223"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1724"/>
            <end position="1751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1229"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1727"/>
            <end position="1740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2199" mass="245718" checksum="F2A9634B0784A2CE" modified="2024-05-29" version="1">MTETYKKASKFNFENNSSMLNSTFDKLLSETTPNFKFTEVKAELIKAKEKLSLESSNETMINADLYWTPLKLACNPNLPAKLRQVAVDSLQKLVAHKLLRGSAPLSKETNLKMNRRISVVNQSNKDTNVNMDIELINRPASIDQDSKDSQQFYLIDEIIYTVCNASPLASPTTNSSEDEVQLQIIKFLLTLLTTTTVEIHTNTLLRCIQTCFSIHLNSKNLVNQVTAKASLTQMINLIFSRMENYSQVLLNKLNVNLEDSRNLNEVNLSIAANNSLESQKDEKSKHRISDSELSPMDNKSPSLVGKSFATSNQNTEGTSNDKDTEEVTRDNNQIHTSDQTEEPLEDRRKFGITDCKTNDPNLIEEKLNLEGGLKTEVDGKIEDKIMLGEKDDTEATIGDNIIESEAKVKENTKNLKKNVGSSEANVNFDEKTHNTSKFLSKKSGNNPYDPTVAYYNELLRKDVYLSLRLLCKLSMHTGNTSHSEHNQTLNEGVNNLMNDELSQTSIRARVLALELILSVLNSAGPVLQNDDIYINLIRQHLCLTIARNGISTHPQLFELSLSVFLMILRLYRSKMVQEVEIILNTIYLHILEMGNSTYKQKSMVLQALLKICENPQTLLDIFINYDCNLSVVSIFERIVNVCAKCSQGGQGVAVPDDGNWTQNEIPAPAVNSGLLSYAASAAGLGSLLGDSKSEVNKIQEKKLKVKSLSCLVAIVNSLVEWSLQVAPALPVVGIGGKVTKTIPKTENVSIKASIEKPNSFLDAIVPTNQSNPVLVDRRPLNSISLVQFSSNLPMTPTGSNTALDQISHYQPTEVEEMASRKQLLKHCIKLFNTDPNAGIALLQTKGFVSSTPVSCARFLLTAQGLDKGAVGEYLGHFEPFNIKVMHSFIDRLNFKGVEFVSALRLFLQTFRLPGESQKIERILEKFADRYCETNPETFANADAAFILAFSIMMLNTDLHSAQVRSRMDKAAFIKNNKGINDNNNLPDEFLGSIFDEISRNEIVMEEEQAGQFATLAIGWGGADLENDKIRMENYRKEIALIQRKSHMLIRAAGTAGGNQNNVEAQVVFRSAVHADLARPMFAMSCWPMMATFSLLFEAAVDDVEDWDTINAEEEAAPKISITSEPKIADLCLQGFSGAIRVASLFRMETERDAFVSSMAKLTGLSHVAEMTPKNVKAIKTLFALANILGQYLEGSWVEVMKVVSSVERLQVAWNMSQDLINQGKNSSGGASQSGSRESLSGSRDDNASASIYTRRSQSFTRPDDLVLAFTSGKLPLNLSKVFTEVSSQSMAVLVDKIFSNTVGLSSNAIIHFFKALCLISLEEVGLESATAGQSVASTPNIISSPNFPNSPGIPGKLSAMSGPPRMYLLQKIVEIAHYNMHRIRYEWSQIWRILQPHFNTVACHPNVSVANFAVDSLRQLSMKFLERDELSHYETQREFLKSFEWIMRHNVHPAIRELILTSLSQIMIARNNNIKSGWKSIFVVLSKAATPPFHIANGLLSTKVNSSSLTMTSAEWEKLTKMSFEMIQVIFKNYVDAVSKAGAFVDLVSALAEFALLEGSSSTTIRNTVSVNSINVLGECGKWLSNQAELDKLARKTNQPPSQLEDATVPLEDSNKMEINHRNLNRRESSTTSLTARQLLSPYTLPNGLISEDHFFLKWFPLVSNMGKVITDSEDNFIQTEMIKILFETLKGAVNLFELKYWKSIHRSIILPIFEDFKENSNNRQKNSIGNSSNAIGNDNQTSEDVERSQSNSGVWPQALQKLVDLFALLLEKISNSIEGLELLESVFELIISMLSKRDEKLATTGQVCLQQFIQRNIGKFIKFNQVIAKDNAENTMELWEVVISVIERACWATSPAELLNCDVSSIAETKTESESPESVTIVQQNISNAPHEAFTQLTLAKVLLAGNKAYLKALSAGSSAKETKIVPITDLEELDLEHTIIKCATHLALMDGIKHIFTTKLVLKSPNSVISLDSPTIPDNTNSTQPVNYTINVIPFQYKKRILSCFYDSYSLARSFNNNLLIRQAIVKKRLMKNLPNLFKQETTSLHNLISLLFTIYRSEGDDSGEEFLEMLVTEILDVFERYVEFLNDQQKNIRDLNLWSPVIVLIFNELLNMDGWWKKIKNNPMQNSGKSDQQQSKGSFSNLEEAHKTVVCLRLKKHLSKFFTFGVKMMGADSPTVRYSLQRFMEVIGEEFIKFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U896</accession>
    <name>A0AAD5U896_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Metallothionein expression activator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ACE2_3</name>
        <name evidence="10" type="ORF">HK099_002882</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000002">
        <property type="protein sequence ID" value="KAJ3228377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U896"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000032">
        <property type="entry name" value="Krueppel-like factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="195"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="225"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="254"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="157"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3228377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="307" mass="34889" checksum="59EF07D256645896" modified="2024-05-29" version="1">MEMTQINSAESQDNLKKNSLSSNYETNCLTSIIVPSSPAQFQNTNSIRSNNLTAFNLSHLNNYPQVPALKSNYMQNFPSSNPTPKFDNCSAEESNIYQNVMHYNNVLTNSPTSYSNSNDQTTTNVNNMFTAYPSPPTQFHDFYANSNDSSNIISSIPVSKSESKKASSISDSVKSVSESSEENGKSESAGDGTKHPCPFPGCKKLFTRLYNVKSHMVCHSGTRPHVCTQCSATFCRKHDLQRHFRTTHSNERPWQCNRCSKSFARRDHYKRHMRVEESLMARRDLAQQVQWENNSHQIVHQQLQHIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8C9</accession>
    <name>A0AAD5U8C9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA polymerase delta subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">POLD2</name>
        <name evidence="7" type="ORF">HK099_006040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8C9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07387">
        <property type="entry name" value="MPP_PolD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.50:FF:000002">
        <property type="entry name" value="DNA polymerase delta small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041863">
        <property type="entry name" value="PolD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="6">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="5">
        <location>
            <begin position="129"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3228160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="396" mass="44748" checksum="0A4C010BE9511738" modified="2024-05-29" version="1">MLSSIQLSHLDSRKIIDLGNNEKAWIIGTIYCEMKLKPNILNELVHNTHSSQVDSNLMKFTNEDDIYVVEDESARIELSGEILKNEKLVTGVTCGLFGFQDEDGKFNVSDISFPKLQPQSNISCSDIWVALISGLNLGNPSSMNIKLQLLIDYLDGELGTHDDQQENCNLTRVVFAGNTLSKPKFVEHDLEEKKTKRFGNDYTPLDTSPIKTLDSYLKQLSTSMSVDIMPGINDPTTTTLPQQPINTGLFPKSSPYETFNTVTNPYMFELEGVSFLGTSGQNIDDIFRCSNMIDRLEICEKTLLWGHICPTAPDTLWCYPFKDDDPFILKQKPHVYFVGNQPSFETRVVEDELGSKTRIILVPSFDETKTFVLLNCNTLECKSITILDEIEEKIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8E1</accession>
    <name>A0AAD5U8E1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GS catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_000030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8E1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF2">
        <property type="entry name" value="TYPE-1 GLUTAMINE SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="4">
        <location>
            <begin position="44"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3228475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="391" mass="44043" checksum="8BD12C53CFB2A219" modified="2024-05-29" version="1">MQTIGEFQLKPIISTLRQLPYYKNHSGVLTIMVQRNGERFSRDPRFFLEKGLDLLKKKFGITLKAGFEIEFTLYTGFDESGNILPLDETVYSETAAFNPKKGGAAEIMDKIVKNLKEQGIEVTMFHAESANGQFEIALEYGDVLNSADNLIFTKETIKHVAALYGVNATFVSKVFANQAANSCHLHLSLWRNGNNITAANSNLHSGKEALEIEDLSEETRKFIAGLLKNLPALCSITMPNPNSYLRLADYCWAGAWKCWGFENREAPIRICSPNGKLTNFEVKCFDGFANPYLGIGAIVFCALEGLENDLSLPPPCNLDPADFETVLEVKNLKLERLPNSLEVTLHHLEKNEVLRKGMQTDLFETFLKIKWHEVEFLKTSKNPVSYLAKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8E7</accession>
    <name>A0AAD5U8E7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PPIL3</name>
        <name evidence="7" type="ORF">HK099_000745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000119">
        <property type="protein sequence ID" value="KAJ3223725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8E7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01928">
        <property type="entry name" value="Cyclophilin_PPIL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000012">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF2">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="10"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3223725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="164" mass="18399" checksum="6E53BE4A18E4774D" modified="2024-05-29" version="1">MSITLKTDHGDIKIELFCLATPKTCENFLALCASGYYDNCKFHRNIPGFMIQTGDPTGTGKGGTSIWGRMFEDEIKSSLKHNDRGIVSMANKSKPDTNGSQFFITYERHPHLDSKHTVFGKVIDGFDTLDALEKVPINEKNKPLKDIFIREVVIHANPIAENVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8G9</accession>
    <name>A0AAD5U8G9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RHO1 GDP-GTP exchange protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ROM2</name>
        <name evidence="5" type="ORF">HK099_008419</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000092">
        <property type="protein sequence ID" value="KAJ3224469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04435">
        <property type="entry name" value="DEP_fRom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF2">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="636"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="4">
        <location>
            <begin position="1082"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="927"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="931"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1394" mass="159368" checksum="42397018EE3DDBE0" modified="2024-05-29" version="1">MSDERLFQQNYRPNNQQPYEIPPRQGASQPIRNFNQQSYLSSNPNQSFSSNLSQQQHFNGAPPPYQGQQYPLQPQFRQQNLQMRPHQPIPNPIQQQYRPQINSIQGPQFRPQQAPYRQPPQQYSSQQNHMQNTQFVPPQGFQVPNTNQPIYRSQPSIINQPINYSTQNFSISGEHAASGRRASETNIYQGSPSLYSNVESEFPPRRSSEALNRTNTSLSMMSPGMPPSFNAQYRTHSNQHFEQRLEAFQRNHSQEFINNSEPIHQRIQPQPTYYRPQYYGEQIRPQSDGRQQLQQGIRTNIQYVVTQPQIRVDEYNPLTMVDFDPRFRPPQVPVTQPIQQEYIIPVRKQSAALTDSQQQQRISDFNFSSEHMVSEAQNGVRMNKVFPVNENYPLVKYDIDGFNEERKYQEEQSDENKKNAESFAIEKRKDTKPVYPAFLSLVADAFRKNITLSTNFKYGLDYQDSFSGKEAVNVIAKVIKTNDRNLALLIGRALDAQIFFNDVTWNHRLRDSSNEIYQFQNVNFAQQSWHDKDLEPDDVIDGLINANNSTINSNSSLPNGIFTLLTDCYSPTCSRDRLCYSIACPRRLEQQNRLAIQTKTDIITEEKTDSNTRKETSWSQSVTKDILESVSTQELKRQETIFEFIQGEINFSMDLELLISVVINKLEEFDSIENPTFTRDESFFFREKVFLNIKEISNEISKFAKRLQKKQTESSDLLIGEIGEVLIDFFGKKELITMYEKYATGHIPAKHLVSTERTRNGPVLVWIEQTLRKEPGFRRLPLDSFIAGPSSRLTKSKLILESILKYTPEEHPDKQNVQQALTLEGAILERINSATGKANNRLKLALLEEQLDIDSSQKMALRLYDQKTVIVRDGKLLMKRLSGGGEVEMNVLLLDHCLVIYRQKSDLMKIKMIIPLELLLTQPSLRPTKKGVSSNRSSVGGRSGNTSSSGLTKKPSFALEEYSHSFTEGVNDANSKSFIGLTGKILQAKGTISHSLSTKSSPMANFNAENITATGSGENSSRFPLTYTKLGGKVASEIIFYCPSESERRAWTEDIEDAKRKRDFENRKFEIIKISENKFSNFNKILTSTSYKGQLIIGGYNGVWCGGEGSAVLNANLIDKFLNSGSNNQNFTKILDIKMVTKIDVLVESDMLLVLSDNQLFSFPLEEIFEEKVLDASLKKGSIISKHCTFFEVGVCMGMNLIVSIKSGNLSSTIKIYEPKPVKIGEKKKSLFKLGMGKENVKLFKEAYIPTESYTLLFLKTKLCVGCLQGFEIVDLDTLNTQGLLDPSDDNKELQSILKKDNIRPITLFRVDRRRTNTEWLVTWLGQPSHFSYFHPYIIAYEATFIEIRDVRTGELEQIITTNNLRCLNTNDYIAVSDGVGDCQQIFKINYLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8U4</accession>
    <name>A0AAD5U8U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cleavage stimulation factor 50 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8U4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005848">
        <property type="term" value="C:mRNA cleavage stimulating factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044633">
        <property type="entry name" value="CstF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44133">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44133:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="164"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="269" mass="30502" checksum="2384D6DD40C7C2B4" modified="2024-05-29" version="1">MRNIYHVQVLNIRLIFYKSNRSYKYIIDFEFLFSLNSNILIIETLSVVNSCSECLSSIDGTHKFCYNCGNPFLLGDGTLLLDGTRSECYINLIVDLQNTDPKPEPEYVTWFNYATQGSLQNSFSPDGKFLATGSKDYSIKTFDITKIKECFLEKNDIKPVLKTIYDHQQPVNQIKFHPNGMVLASCADDGFIKFFDLVKPSSKKTSDIFNYNEDYVFGSDDSGFGVNLIVLQMFLAHQNVVGYVVASLVENAIISCSEDSSARFWMGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8X2</accession>
    <name>A0AAD5U8X2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Trifunctional dihydropteroate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">FOL1</name>
        <name evidence="17" type="ORF">HK099_005139</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the N-terminal section; belongs to the DHNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8X2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="16">
        <location>
            <begin position="424"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3226308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="718" mass="80187" checksum="66F320F35F5ECFB3" modified="2024-05-29" version="1">MDNWSRVKEQPLILNVTMEIEKLDERDNLKKSVNYSTINNDITKTVKENQSIKTIHELAQKLSEVILKNDVIKNVELELRKPRALLLADYASCLISRGRDHKNPTDLTIIKNLNLNAIIGLYSWERQEKQRLTLSLIIHLSEKSHDYRTICNVVYEFVDESKFKTLEALALAIAKTCVVDCLVPKITVQIYKPNANTFADSTSVEVTRTFDDFNFIKNAQHLYEDVDLNHTAFIALGTNEGNRSKNLELAISKMNISNLLKVKETSFLYETEAMYVKDQPMFLNAVVKVSTSMDPKVLLRYLQNIEKELGREALGVRVTNGPRPIDLDILYFDDLTIHEKDLIIPHARVHEREFVLRPLVDIAPNLEHPVLCRTSTQLLSSLEYNFEVLKEEERENGHPISTKPAIYKVYPIGDKVWKLCNGPTILMGILNVTSDSFSDGMNLMNSSEEKLNMEKVLLKVEALIEDGAGIIDIGGQSTRPGADEVSLEVELERVIPVIKAIRNDPKLCTISISVDTYRPAVAAAALEAGCDMINDVTGGLGFVDDDEGDLAQTEMIKLWAKTKSAVCIMHMKGSPKTMQSKTDYRGEDITSSIKRSLQKRVELALSAGVLRWKILIDPGIGFAKTVKQNFKLLRDLKVLVSNGHLKGFPLLVGPSRKGFIGAAVNSKDPKDNKRLYGTAGACSVAIASGAVLLLRVHDVKEISSVVAVADCCFNPNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9M0</accession>
    <name>A0AAD5U9M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000067">
        <property type="protein sequence ID" value="KAJ3225236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9M0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3225236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="453" mass="51324" checksum="A482D4144F2AE6A0" modified="2024-05-29" version="1">MKDNLKINRSIKVENCNSYFRNRQDRVKHLKNAHGDASKEGTAVIENKKKSIKHQYQKANNVPFSNSSTLNVIGGADFLSPPMTPHDSAFISNDNFADSSVYLPADTNGIKGFPGVAELTPNSFSQYHNSISPFVGSEVVLSSNNFFNNSNNMNYETLPLNMFITPKCIPSVGFNWKIFLRSFLFFNFSAGIDAEQDAVNKIYDYGKNGGLVPVNAQTSIYVDVLERLKNLNLDIPSILTKRQSMLIKDMVKGGGVMKGFRKILTELKGTLLYDAELKKLSSSTSGVNFIPAKILSELLMFILETYRRTMNNDTTVELVEVSHKSRNWCNPGDCGKSQLGLRFKLPYIEDIRVVYLKKQEFYAFTESVKYDLQKMVEEIVWGDEHESILIRELCCKGLICDLGKLNSKINFNLSLIDSGEKLDIKYFMKIGFDKHWVMEDNLRDSDDLFVVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9S6</accession>
    <name>A0AAD5U9S6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ANXA13</name>
        <name evidence="6" type="ORF">HK099_004508</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="4">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000032">
        <property type="protein sequence ID" value="KAJ3226627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9S6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0041">Annexin</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3226627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="680" mass="76238" checksum="95F2B851C9493BD5" modified="2024-05-29" version="1">MSQSNLSNKSDYENFKSYYSAPSSISFPEPRRSSNPNVLNLNPFLPVQLPTTNESVPLPTKTTLPSTEIVSSPQPTVIYVTQPFLIYQNSKSQIPFPKQPDLPHSGSNDPDKVNDTQNKKQPVYPLFERKNPKIFGNIDNLKSAGNVIADSNNLKINPQNFKEHSMKLSNSIVGKSQGNSVLVSNSGGLASEIPSVSGSKNPISQVTEGNLLKSNLTQDGKTSDNMKPIAAIMENKLETIDFLPKIPSVANNWNFESLHIDSGKTDFSIPDFSVNLRPATPLSKLAELKLEEKEVTTEMLDHKRRSSNFSVNSLPSYHSNCSSFSPQKNNLNLNTSITPVVFSGDSPKSPPPGSSPSNSYYSRRGSHAPKPVSLEGDIEALLRCFRGVTADEKILFDIVGRRPLWHLDQLAEKFRDQNGQTLLHCIQRTTDSLIFETSKAFLTSWFDYEALCISDALKGLFGVDMESLFEILSGRSNFEMEQLKIHYEKLTNERLLSSINNKVSNNMRHFFNILLRTVRDESEVVTPEKIESVSKLMVEALSRRKTDDSQILTILCMHSKEVLRESALKYELKKKRGCEESVKRHFHITGDSEKGLLSLMRAIQDINEFAATEIEKSMKGLGMKEFKLIRLLSRFTRLGALKKVAETYNMKNKITLSERISKETSGGFRDLLLACLEREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UA81</accession>
    <name>A0AAD5UA81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Palmitoyltransferase</fullName>
            <ecNumber evidence="12">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ZDHHC13</name>
        <name evidence="15" type="ORF">HK099_003125</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="12"/>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UA81"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0564">Palmitate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="119"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="152"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="219"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="14">
        <location>
            <begin position="398"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3227162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="429" mass="48397" checksum="451743490C6A3B62" modified="2024-05-29" version="1">MLKSLFGHKHSHDDKCRHGKEESMFDDGTKSDNNDDCETIPLTHSLEQENINNLDLFQLAQRGLKEDFIFELQRSGNNPDLLDNEACSSLHWAAINNRIEVALYLISVKATVDIRGGQLSATPLHWAARAGHIHMVTILLKNGADPTLFDGQGYNALHLAAHAGHHLLMLYLNAIGMDWNTPDSASRTCLHWVAYQGNSLDSLKSLLKHNVGLDFLDNSGYTALHWSVIANHLDFSYELVKAGCNIDVKDGQGKTALDWAKERNTDEKFQKMLNDYYKETIKNNWYISFPVSLAVLSLIHNYIFMGYLLGNGQIKPVHTPYLTSIPQATIFYCVLDWMTMINDSGMMIENILMCILSAVLIYSFYKSVVLNPGYLKLNLSQTEKQAVIIRLAENGNLDARHYCLTCEVGKPLRSKHCKICDKCVAKFDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UAD8</accession>
    <name>A0AAD5UAD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000018">
        <property type="protein sequence ID" value="KAJ3227366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UAD8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042080888" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="118" mass="12899" checksum="51E96FBBDEAC33D4" modified="2024-05-29" version="1">MKFPLYLVITAILTYVSSSHLSSSSLDTTQTKDHPKLFNLKNISGEGRVKRSLKIANDNISGEGRVKRRLRVSKDNISGEGRVKRSLNVVNDNISGEGRVKRSLNTASGNISGEGKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBJ7</accession>
    <name>A0AAD5UBJ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001416</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000014">
        <property type="protein sequence ID" value="KAJ3227567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBJ7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF28">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="10">
        <location>
            <begin position="177"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3227567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="668" mass="74641" checksum="4A578CC7EB30469F" modified="2024-05-29" version="1">MSNTTEVECIVDTNIYFQAESYQFGLMTVVLLYNAFSLKKYRKKKSIGKLPLVVSVLWVITQVLFWQPCYFLYYYDVPAANVVGVIEGIFDSLTKTFLIYYINARLEIVSDLSRASKIIWFAFIASGTACAIGGNLLFWIPVVFPNLPAYPSDYGNGLYLIGDAMIGLQDFIAAFMFVYNYSQVYNVSNFIDAHPGGKRIILPLLGKDATQEFHQYHTGKTVLAKYTKSLLIGSVEERKAEDDNTNDPTAKNFGSMITFADPSWYQAWKSPYYNDSHRRLRHWARNFIEVNVIPFVYQWEIVGKVPKELYQKFGEAGYLNGILGQYPWPKNVGPPPAGIKPEEFDVFHEQTLIDELARCASAGVGFAISLGPSIALPAILNFANKDLVNLIVKPVLEGKKTICLCITEPYAGSDVASIQTTATLSNCGEHYLINGEKKWITNGTWADYFIVAARTGRQGMTGITLFLLKREMVGLRTRPIACQGNVGSGTAFVIFENVKVPKENIIGELNHDERLGIIISTIRMARICYEEAMIYSNKRKTFGKFLFEHGVIRNKLAHMVRKIEASQCWLEYILFQIKNLSKSEANVILGGPIALLKAQATTTVEYCAREASQIMGGIAYTKGGVGEKIERIYREVRGAAIPGGSEEIMLDLGMKQALKISKANGAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRV9</accession>
    <name>A0AAD5XRV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease P protein subunit p30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPP30</name>
        <name evidence="4" type="ORF">HK099_001837</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001567">
        <property type="protein sequence ID" value="KAJ3202474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRV9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002738">
        <property type="entry name" value="RNase_P_p30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01876">
        <property type="entry name" value="RNase_P_p30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3202474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="223" mass="25273" checksum="B28A4311B775C93E" modified="2024-05-29" version="1">MFYDLCSKKNLIEKAQKLGYEKNVINEEITQTELQKRMSQKQQQSEKFDRVTIIVENDTKPLNFLSNLNANLVAVRPCGEKSFFSACSSSDIDIIQFDFSERLGYNLKHTTVNLAIQKGIYFEICYSLAIEDENIRKNMIGNSASLIRATRGKNIIVSSGASNPIYLRGPYDVINLCSIFGLNSYLAKSCLLKNCRKVLLHADTRINSLKGIISLKRKAEEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XT44</accession>
    <name>A0AAD5XT44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Demethylmenaquinone methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000915">
        <property type="protein sequence ID" value="KAJ3209984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XT44"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047443">
        <property type="term" value="F:4-hydroxy-4-methyl-2-oxoglutarate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.40">
        <property type="entry name" value="Ribonuclease E inhibitor RraA/RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254:SF4">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605493-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="20113" checksum="EE715E076C3BC61A" modified="2024-05-29" version="1">MDELISKNYSTGDISDALSKLGIESYIPDIVIKSPIQNCQNIKVVGFAHTRLLGTRAKKIGVKGVVIEGRLRDLKELWDMEFPAFATGNSTMGAAPFSRVSTVGEPITLAADTIAPVVVKEGDIIVGDIDGVVRIPKDKLDKVLKILQFLTLQDEKVLQHILKGETLKNSFEKFRKPLPTELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTC8</accession>
    <name>A0AAD5XTC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_008046</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000843">
        <property type="protein sequence ID" value="KAJ3211308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTC8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057939">
        <property type="entry name" value="TRF2_HOY1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24818">
        <property type="entry name" value="PH_TRF2_HOY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="37"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="39"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="472"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3211308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="537" mass="60101" checksum="4D2516CFFCC085A4" modified="2024-05-29" version="1">MTFSEMFTSLSNGPPNNSISDQLLNDQQRELNAASYEANQKKRTRATPEQLLILEETFQQNTSPNAKLREILSEKLSMTERSIQIWFQNRRAKVKLLQKRAVNNNTLNHHQRNYLHQNSATSPYNPSNGFNRSNPIDFNHFQVPQKPPNTIVSNTLLLSNETLSIGTWRRVALCNDDLLCTISLADSIIRWQIVESANKFKLEFPITAITSITLDPVTDHSNKPNGGGQLSVFLSKAPIFFMEINNGQGNVWTQCRDFTEGHQATKNFQHILQGNFNNLHAELMNLMQFDQYFNHITHINTPNTLAVGSLNSLKRPSLSNTSSLDDLNQFSFPRRGSCPTSFFDSPSFKLRRGSVLDHSPSSNPSPLLEATSVDFDSPLLGSPLALPLQLYPQVNNFHFNNGTASASPNLYSEFNQLNVLEDLNFNQNAFTGTSNNVNNSFMGNLMNNGSQQNDLILNEGVNFVADQKLREKNREENQNPKQVDGVNSAPPVEDTNNSSDGKNSSAQNTDFLFDIAQFLDSTSSSSDIGFNDNLISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTL4</accession>
    <name>A0AAD5XTL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SET and MYND domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SMYD3_2</name>
        <name evidence="7" type="ORF">HK099_007656</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000760">
        <property type="protein sequence ID" value="KAJ3212846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTL4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF292">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="61"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3212846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="336" mass="38780" checksum="65429464DD1A29CF" modified="2024-05-29" version="1">MEKCCSYCQITSKKLSCCSNCRKRLYCSPECQVQATFLFFEILDWKPNHKLWCGNAGEKDYDYCVRETKNGKGFGVFALRNFEVNEKILINRVFNLHSMPDTTAASLKLLIPTSNDIKKYYVSFVDSQTEDHKKGICFDISRVKHSCLANSLPCIINQNYGALVASRKIDKGEEITISYVKGKVLKRIDESTLEERRKLLFSNYGFQCECNGCVENSEEWALLEELESINKTLREDAFMKNPMELIELLKKSLDLLKILNQSNFFLSKTFSLIFLWDCCLKKKMNNQSLTFLKSSIELMEGFYGFQSEMVIKLKELENIPEGTGVAEIINKFKSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTW7</accession>
    <name>A0AAD5XTW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-mRNA-splicing factor cwc22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CWC22</name>
        <name evidence="8" type="ORF">HK099_007054</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000653">
        <property type="protein sequence ID" value="KAJ3214051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTW7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000004">
        <property type="entry name" value="pre-mRNA-splicing factor CWC22 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="7">
        <location>
            <begin position="363"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="314"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="579"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="592"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="620"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="636"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="701"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="785"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="830"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="872"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="900"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3214051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="913" mass="106340" checksum="94FBA5DD605307D2" modified="2024-05-29" version="1">MPITSTSPNNVNPTNENEKDQIDPELGITEKEKQALLGRAGGVYIPPHKLKLLQAKVTNKNTDLFQRMSWEALKKSINGLINKVNTANIKMIVPELFQENLIRGRGLLCKSIMKAQQASLPFTPVYAALIAVINTKFPNIGELLLSRLIMQFKRAYKRNDKTVCIAVTKFLAGLFNQKIVHEIIALQLLTLLLERPTDDSVEVAVSFLRDTGSYLTDVSSKATNSIFERFRAILHEGVIDKRTQYMVEVLFQVRRDKFSENPAIEKGLDLVEEEEQITHFVSLDEDYKSEEMLNIYKFDKDFIESEEKYEKIKKEILGDDSDDESEQGSDESDESEDEVDEANENDNQKKLQIIDETNTNVVNLRRAIYLTIMSSLNFEECSHKLMKLNLREEDQMELCNMIIECCSQERTYLNFYGLIGERYAKFSQVWAEHFCTCFEETYKTIHRFETNRLRNIGKYFSHLLSSDAITWQVFSLVKLTEQDTTSSSRIFIKILFQELVEALGLVNLKKRLQDPTMIITVQTESGTIVRGAFDGLFPKDNPRNTRFAINYFTSIGLGGLTEDLREHLKNAPKLIMAQQREGVESDTDSDSSSDSSSSSSSSSDSSSSDSSSSDEDEKSRKRKSTKDSPRRRKSVSPRDERRGGDRRKRSESPRDRRRKSEVSPKDERRGEDRRKRSESPRDRRRKKSDSPKSNRRSGISPREDRRRSAVFQREDKRRSDISPREEKRRSDISPRENGRRSDISPREDRRRSDISPREDRRRSDISPKDQKKRGEVSPRSHRRRPDLSPREKRREDRSSRRDEVSSPRERKSRQESPRRRDLLSPPKKRRAEEEPRKPSEKSSSRHRSNSRERGRDDEDYKKRSSRYNSPSSRREENNGEKRRKVEEDVSERRQRNRSNSSDRGDDNRRRKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUR6</accession>
    <name>A0AAD5XUR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000463">
        <property type="protein sequence ID" value="KAJ3216720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="245" mass="27805" checksum="5F1FC4A53E32A706" modified="2024-05-29" version="1">MHISKSQRYMKKIHNLFNSTSNSKKPLRLIIDQNVVTCNPKMDILKTPTQRSPISDDHLDSALLSSKDFAKACGIVVLQDSDEETDDTLNRQPLERTYSEVSGTTLSSLSRLSIMSEPPVNYSRRASIFDSDLFTPPGSIDSAVILSTSNPSPTFSTNYLKSKINLNLELSDDEEPNTLQEQKGRFTVVNKNIHKRKGHKRRFSVTTLPSEATLKHNFHPISEETYTLKRNLIPRINEESRRKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XV37</accession>
    <name>A0AAD5XV37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000393">
        <property type="protein sequence ID" value="KAJ3218161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XV37"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="82" mass="9269" checksum="82542A9087AF9107" modified="2024-05-29" version="1">MIKQSEQESIHSQLSELIQDLNFSNEEIELDSNLNTQQILKSMQKTNEMLDTLEGKTDQLLAKLDAILSENKNSSTTSTVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVY4</accession>
    <name>A0AAD5XVY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001427">
        <property type="protein sequence ID" value="KAJ3203453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVY4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="1">
        <location>
            <begin position="24"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3203453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="97" mass="11008" checksum="3A5764ED5C670B06" modified="2024-05-29" version="1" fragment="single">MIETKYDLLVKSMVHDFLDLAAPENQNNKWSQVAKVNEGKILVFKLVGSTNCFKVIAELDTSAATAFDILADVTRRIEWDELCEFGQVIERIDNKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW14</accession>
    <name>A0AAD5XW14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001374">
        <property type="protein sequence ID" value="KAJ3203830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW14"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3203830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="247" mass="29061" checksum="2443A9DE8E355711" modified="2024-05-29" version="1" fragment="single">DNWCWYYWDRVGTTEEAFNNLPSICHTLKFETSPYTYASWIVQVWFKTITDLFLGLWLLKLLLNSKKISKVFKSVMESNQKFKYINLQENNNKNKKKKNFLKNLFNKRKEEGEEESKNLTKRNKFQLERVRLSLVKFLIIWMGLVLGIVVVYTINRIPNENFYSLNKYSNFNIIEVVNAVLQIFRSLELLIYFKYMDILKSIVGIGAIKISTGVTQLSSVDGFSKPNKATNSSRDYDSEKDFQDSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW30</accession>
    <name>A0AAD5XW30_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AN1-type zinc finger protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ZFAND1</name>
        <name evidence="6" type="ORF">HK099_003721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000247">
        <property type="protein sequence ID" value="KAJ3221169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW30"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057358">
        <property type="entry name" value="UBL_ZFAND1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF20">
        <property type="entry name" value="ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25327">
        <property type="entry name" value="UBL_ZFAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="5">
        <location>
            <begin position="58"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3221169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="263" mass="30655" checksum="4F1462597024886B" modified="2024-05-29" version="1">MDLAIGKHCSNSDCKQLDFLPFRCNKCELFYCQDHRFRHKCREEELTGNSPPKKKILDSDLKECFLSECNVKELFYSTCSQCSRNFCLRHRHPTDHNCESVQIKQNFQQAKSNEIKDLISEKLSSSTKIENSNKIKKPKKVNPAIELTRMKLHAMGDKGIPVESRVYFQVHLPLESNNKQIFKMFFHKDWTVGRTIDKICLLNKIENVNNKMNLEEKKISLYDTEKKLIIDTSKTWQDLISSNLITNTQQITLERDIAFASGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWE5</accession>
    <name>A0AAD5XWE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007409</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000715">
        <property type="protein sequence ID" value="KAJ3213407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWE5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22453">
        <property type="entry name" value="KH-I_MUG60_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056553">
        <property type="entry name" value="KH_Mug60-KHD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24563">
        <property type="entry name" value="KH_Mug60-KHD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="187"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="515"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="600"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="984"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1003"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1131" mass="127376" checksum="7323FDF9622AA16C" modified="2024-05-29" version="1">MEAQKQQPLNDNTKNIQNQQHTVICFCYNVTIYNSSESTQQLFYKNVSDTLRSLTTETSNQFNCEINISSPEFLNKVNNLHHFKFTIVIIGPPNQAVDAKGYLMRKNPSQTESTLSLVKNLILKDNGEMKSDFKRRLDEIMLITKTSINFSKSGNVDSNLDLEIMGRLDNVDQARIQCLVALDEMSGLHSETMTIDKRLLTIIAGRKRETLNTVMKDTLTNIYFPPYLQIDEVLMAPQPNDPNWHNDPNHKAVIFITGLKANTLIAKSQLSEIAENKKRSLTIKVVVCISRKLDWLFLNHKEKLKKIMSDNATILILPKLGSSSNMLTVIGDEKIFVERSIRTLMIFICGFYVACIRRQPITQTSSAQGMYKIQQPNYNGDRSAAVAAAEYDSKGEFINNVIQNACRNSGAEIILQPQYVEVCGLQTAVKYAYESLSGTEFFRTSRDSKFQLELALEHREFINGKKNGKINKITKASSSKISFQENFNGYNMLIEIQNSSPLKSLEGLTLLEDEMPAEISFYVPESFHKRIIGVGGKNIQRIMKKYGVYVKFSNSEEFQTIGGYFENMDNVIARTPAKNAFNLNELKMSIIELITTKENYEKKTFVKIPRQHHKVVIGLQGCNIADIEKETNVQITFPDVESGVEEFVIQRGDDDEVQRARQCLLDLVPEVCEIQIPSISRAKEAIESMEFYSEVVQKLKAEKSLLDYFFYFPKTNNLSPTLRSSDRATNVVENYGSSVISILIHFNPRVCNSDHIKAIVNKFLTSKEVNLVQDKVISRVASSSSAGNAFNQQNVARTSSYDSFQHFNSKLIAPVNPSESIVSVMSSTYSLFDGANKAFEFSDPRNPKQAHSAPNLRLLFEDALYPNSSSQILNNGQPSLRSNLSESYNHMFSRNNQTNNNADNFDDDDIHHDDNFHTQFDILGETLAATSIGGLQGIQKGRNLLNPSRSMDPAVFGQGFNTNSGNPSDPSINFWSVRSKQNSNTSLIDDSTHNTEKLTTSSPQQQQQPIPRIPTDNVRGLQLSRSDPNTNKIFEEKTKQRTPSKLRQHFDAEQLKNEKSEPKRWGNIAGINPHAPSFEPSSSSSVTTFETSSSTIQIQKTTTQTTTLSYTNAVLQNSKIHTTANLSVKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXN2</accession>
    <name>A0AAD5XXN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_008327</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000090">
        <property type="protein sequence ID" value="KAJ3224528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXN2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="560" mass="63784" checksum="A14E05C604C967B5" modified="2024-05-29" version="1">MECNCYQPLVLTTIFNPEKGIFVRAIAFLTAQIFECETLPFKVKRKEKMTNNLENDTRVRTQSYNSTTSDNLAPRLRKRISSGNYILRRTSSFGGGPVIVINPQDSFAIKKRTSSKLRWVNLTAYDNPAALNRPLQKYLDHNYDDYQYELNLFYSVYSFPNMFLPFIGGQLVDRLDTRKVLMAFRNKELAFALGLNLCVARLGSVMNSVMSPRIESSYSVPVAIWTGSLMCYLSFFSAFILSCLIAIKKLPEDKEEHEEHIPILSSLNNELSGHQRLEERASPRKKILKQGLVNLVNESTRIDEAQEELDFNLKTTVLNRKNTEYPNSFFTREPEAMNEGSSLHSNTKRVEFSSDEKKTVVNFLKETFFQIKLLPKEFWLICLICVVLYGTVVPFNNIASDFLMSKWFPGDTKKAGHSRYDECYISASLWDFGGPAWWTCNVVIDLFTGLSYSFYGVALWPSVATVIDSHEKKLEDDGSVCSRKLLGTAYGISTSALNTALTIFPLITAEIRVHSANYQWVLTFFLVLALIGSIACVILYYFDRNNGGLLQKPEVTEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY95</accession>
    <name>A0AAD5XY95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_005954</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000049">
        <property type="protein sequence ID" value="KAJ3225898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY95"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000038">
        <property type="entry name" value="spermatogenesis-associated protein 5-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000012">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="213"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="431"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="673" mass="76023" checksum="70B4409EB6D86704" modified="2024-05-29" version="1">MRILKFSVPEDKDTSRCRIPNHYFKNQNVLINQWVNLITETEVLYCRAWPFTKNEPSNLDPFVQAEDIIRREVFRNELKDLQIGGANVFISCDEFSVKVDRELQNSVYQLCGLAFRKDCTIRIDLGLRKIDVKVVETIPQNKDCIVDQLTQIEIYKVEKDSDIPNNTQYELENAMCNLSFSLPGLEEAFNLLFEAVSYPLLHYNLLQEMNIECLKGFLLYGPPGVGKTFLVSTIAQKCKIGMVKIDGPEVYGSNLGESEEKLTKKFEAARKVARLGNGCILFIDEIDALAPQRANTSQHESRVVAQLLVLMDNVLQEEAKLVIIAATNRPNSIDIALRRPGRFDKEIAIDPPSVDNRKKIIQQLSKKMRLENNFDFEVISVLTNGYVGADLVALCREATLLAMQRNKDEQTELCTTTNDFKNAMKAITPSLQRHALALTKELSNNLSWSNVGGLEEVKLKLKQMVEWPLKYKTTFERLGLTSPRGLLLVRNDMFIRSTFQRAREAFPSIIFFDEIDALVGKRSLDGGKGGISVSERILSTLLNEMDGIENSDGVLVVGATNRPDMIDAALMRPGRFDKVLFVPPPDEKSRLSILKIHTTGMALKDDVNLKYLAKNTVAYTGANLEGLCREAAMYALRESLNADVVEMRHFEMALLVTKPTLSEEALKSYKKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYJ3</accession>
    <name>A0AAD5XYJ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubby C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005975</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TUB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000491">
        <property type="protein sequence ID" value="KAJ3216204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYJ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.90.10">
        <property type="entry name" value="Tubby Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000007">
        <property type="entry name" value="Tubby_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517:SF7">
        <property type="entry name" value="PROTEIN KING TUBBY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517">
        <property type="entry name" value="TUBBY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01167">
        <property type="entry name" value="Tub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01573">
        <property type="entry name" value="SUPERTUBBY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubby C-terminal" evidence="3">
        <location>
            <begin position="95"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3216204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="323" mass="36291" checksum="FB3F4936817741FD" modified="2024-05-29" version="1">MSVKEDSEESEESEDGTSKLEKNKLIKKSSAEEAADDAEAVKITEPEKRTEVEQDVITVEPKVETAVDVSAPALEITGLGLNVKSLLVIAPELFQRISKESILRCRVFRKKNILDKAHPSFFMYNEGDEKFLMAARKRKKSKDVNFIISKSLDGLTKNSKDYIAKLKANSQRTNFILMDARNFNEKAGNKGLKEIGVINYSKTVLPREMNVAIPLESIEDNSANCVDILKEMSNKNSDKIMFLKNKTPRWNDATQSHCLNFGGRVSLPSIKNFQLVSEKDEQTIIMQFGRCGPDFFSLDARWPMTPVEAFSIALTAFDAYDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYR2</accession>
    <name>A0AAD5XYR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyridoxal 5'-phosphate synthase</fullName>
            <ecNumber evidence="4">1.4.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_005149</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYR2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004231">
        <property type="entry name" value="PRK05679.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851:SF0">
        <property type="entry name" value="PYRIDOXINE-5'-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PYRIDOXINE-5-PHOSPHATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="PNPOx_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyridoxamine 5'-phosphate oxidase N-terminal" evidence="8">
        <location>
            <begin position="8"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridoxine 5'-phosphate oxidase dimerisation C-terminal" evidence="9">
        <location>
            <begin position="144"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3226318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="184" mass="20978" checksum="5A037B76C19600F8" modified="2024-05-29" version="1">MLKKKGDEPNAVTLSTCGKDLKPSSRVILLKSFSDDGFVFFTNYNSKKSRDLMENPNCCLNFYWNLPGGLVKSVRIEGSAVKLSEKLSIDYFKTRPRESQIGAWASAHQSSVLKGGREEMMSNLETARNMFANESIDIPKPDFWGGYNINPTKIEFWQGGFGRMHDRLVYSKDSEEWILERFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYW5</accession>
    <name>A0AAD5XYW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MCA1_1</name>
        <name evidence="6" type="ORF">HK099_002648</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000019">
        <property type="protein sequence ID" value="KAJ3227284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="589"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="615"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C14 caspase" evidence="5">
        <location>
            <begin position="160"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="701" mass="79110" checksum="6787FF739E1D30F1" modified="2024-05-29" version="1">MTGKIQIVFLGFHSTTNTSSSPAQRILTVLPKHDTKTITEYLNEIRKLHFKDCQSITENAIKNSAIYTGPPDFWAITASDIKKLPKALAELNIKDLPALPTSKPPQIPKLQVESINKNVHKSSIKNTNSSSNFVEDDNISIASLASQGKLQSVLQQRLPRKKVLLIGINYFGQPDVELKGCINDVKNMYKLVTTRWGYKNTPEEMKILTDEKDDPKKLPTKANMLEAFKWLMEDVQAGDSLYIHYSGHGSQQEEDGDDYEEDGMDDTLVPLDFQENGQIVDDDLNDLLVKSLPEGAKLTVFMDCCHSGTILDLPYTFDKNGTLSNDPKMGLLGASKGEIVMISGCMETQTSADAKIAGMATGAMSYALLKTIQDKGAKISGRQLLESIRVHLITIVLPVVRIILKLRKFKLREILLITSTQFRYTIAILFVISASQLINFLRYTMALFPNEDLILERGMELGVSSHYYFNQQNDIPVYNVIGYANICLSGTLVIFMVTNRYKKLEMVLQNSKKDKLIRYIRIKVLTIRFINLTTNRLSIQYTILKYFIMYIAAMFLVIDLIFNLKMIKNVLRIPNPENRKRQVVVKTKLYLIMLTSVVLDSASTLLYLYSPKMGFVNIGAGLAYLHLYLTTLILELIYNYNKELKNCKGLKKSYINIFKKQCETSVTSSPSNIVANEISNFESYVSMSPSAISKQIDLSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZR2</accession>
    <name>A0AAD5XZR2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000293">
        <property type="protein sequence ID" value="KAJ3220536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZR2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="626" mass="70413" checksum="9F05CE9961D8250C" modified="2024-05-29" version="1">MLTNPNNQDSDSKQIANASNTQSLTVNNKAVDNNEVIDSLNSLKQISLQALNSVVQRLVEEEVAREATVEDIPPSPTSPSSPSSTHSASNSNSKLSKRTSFTKPLTDFLSIKQNNDKSLHSKSAENFSTNIIEIEEQDKVSFADMLHNSAGASSLNSDVLSREVVQSLPEKLKEFEHNRRVSIGVTNKSLDNNSQSEVKIKLELAENKFETDHNLALALAALCNGLYQILETDALPSNSESYQSISSNQNTPCEHTNSVQDVLSNNIVVVDGNSPSNTSPLENNAINLVHQENIITQLQNVQAQRPDLNNSSQDQRSLWSETDRLMIVIQEICKKKHLSKDLPSYEDVVKDSKNNEKVSLCSEKEKSEVNERSLENVLVAIDRVQRLAPRAFGQDVLMSENFKKKINQAEILNLLDRLLKNNEQFNGQRAFVDSESKFSKLNVLVDLITASHKRSLMDQKATLSDGNAKMMEIGRITKVIDIQSKRRFKDQDWVSPEQKLIMDLNKLQQELEKISSKKLNNQRFELSDGKVKQFYIGGVLKQMDKLQSRKLNNQCAMSSGQKQEQKFEDIEKLLDKLNKPSLKVDQRASINSRDEIDKLMDKLTKPVLVKDQRACINDRSKSPILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y182</accession>
    <name>A0AAD5Y182_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004789</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000035">
        <property type="protein sequence ID" value="KAJ3226479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y182"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="342"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="470" mass="53882" checksum="B245A50FBFE42CDC" modified="2024-05-29" version="1">MNAIDGLPLTSRQSALHMNNQIFTFGGYVDHKNTIDSNNINIINPISKKLMKSVGPKNSSISPNARASSCFLPYSADDKEFSEESFSSTSPEKTPPIIMLFGESSKDGIITRHNDVWLAKILVNEVEWVRIYPKPDKLTGLSPNPTTLNSCVRHAFMGTNTVFFFGGITTINDNETRLTNSIWSLSQNRDSLEWRWQLITTHDANLSNSNDLVPTSRATSIFNIENMQLLIYGGFTDLNNIPKLYIFDLCAMKWVERVNRNYDRMDCPEKISVFLVVTTALILIFAVLVILFISKKFRKSQFLEKFIMDINSGNPENKNNWKYYILKNRYFKKLATVFKISSISTSKKLVSDRIHKGHIPQHDDQIIVNVGDIFEIREIYLDDWVFGFNVNTSKEGIIPLNCLENLNPLDYPEILNNKRYKPLVHGLDQLGNNHNEDFNSYEAQLRQRQSQRISFPPNYAEIQNDNIATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1I9</accession>
    <name>A0AAD5Y1I9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000021">
        <property type="protein sequence ID" value="KAJ3227181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1I9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="182" mass="21938" checksum="2E3536256842876E" modified="2024-05-29" version="1">MFHWFQRNYVPHESVLTEEEQLKNTNVRPNIKVQEVIEETRTNPYYPLSGPPQNEKEKQMLQEMIREEHNNTMDSLIRRRKVEENDLTFLANLNCSDLMLEFRYCRMFGEFREKSCGCGEKKFALDDCVRFNKNAIRELGYFAAKTKEEKEKVLDNADAIYLKRMKARREEDMEMEREMTMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2S2</accession>
    <name>A0AAD5Y2S2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000071">
        <property type="protein sequence ID" value="KAJ3225100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2S2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="218"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3225100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="320" mass="35835" checksum="6375FDA37C017DA3" modified="2024-05-29" version="1">MATNGTSVLKPFSCVPSDSGTTAEGSVAFKFFDDEACGKESTSNITDTAKELPRLSGEIVNFKGPTPCGRVITLGNINAKSVQLDWSGSINMKFQKGDYKPSATSSGCECSMEGEDIKPKQCLVVGTYPIWEGNVVMLNGNTPTSAAEGRRKVRGVKYISFDFIDGLDYLNKKKQSIPLYEKIQTKYKKLKPILSYAQLKFINLPISNYQITNLSKKISIGRSESSTVQLTGSLHLSRIHCEIEWSNCFDDKENLENTSPTLENNENLMIFNSNYGWRLEVLGKKGLYINNKFYEKNYIVRLVGGEEIIMDSYKFQFLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y338</accession>
    <name>A0AAD5Y338_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HTA1_3</name>
        <name evidence="14" type="ORF">HK099_006190</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000052">
        <property type="protein sequence ID" value="KAJ3225792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y338"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000008">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="13"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="13">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="139" mass="14836" checksum="A0418B17D4E51C4D" modified="2024-05-29" version="1">MAGGKGKSGVVASAEKSKSGSSSRSSRAGLQFPVGRIHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGNVTIAQGGVLPNIHQVLLPKKTDQKMGKKGEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSI2</accession>
    <name>A0AAD5TSI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002065">
        <property type="protein sequence ID" value="KAJ3199661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSI2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="27190" checksum="A5F9E50A2C42644E" modified="2024-05-29" version="1" fragment="single">LSKGFGFVSFEKVEVATQVKNMKNLEIDGRLITVQSASIKPVKNANDRDEFFNSRSRMNERLVADRGRDYDYDRFDDRRPVRRDRDLSPRGRFEERIPLSPHREYDRRLEYGRPERPRRYYEEELLPRRSYDIRRIPYEDEFRRESRPPYRIPLDDYREERYHKLPSYDDKRELPRRYGRELETYGYDRRFDGDFLRGRSPPSYDIRSRSPFDDRRGRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSS0</accession>
    <name>A0AAD5TSS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_003234</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002149">
        <property type="protein sequence ID" value="KAJ3199275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSS0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3199275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="398" mass="46321" checksum="EC19A3CE056D2683" modified="2024-05-29" version="1" fragment="single">TDKKYPKNKLILWNEKKRKIVFEINSRSEILNVKLKKGVIIIILKNKVDIYKFSIKELPIKVFSIDTTQNLLGLCSISKFTTMFDGHECLVLAVPGKFEGQIQVLHLPLSLKTEESEHCLKSKHISPHESAVQCITISNDGKILATASEKGTVIRLYCTKSLKKLNEIRINLAPSIIYSVNFDLKNSKILCTTDKGATHMFNLKKRNHYVNDNNNKVDLKKNFNLDVNCHSPSSNTNNKTNQISKFFFPLSSYLSSIWSNATFFQKKKTNFSLAKFNFNYQTTESEKDEDEDEDEEAQEENFSMEFRDVKIKNKKKSIYLKTFLIFDDGDFFKLNFNGQTFQIEIFKNLFFNLNVNNTMENEIVLVEKNMSSNENKFNYFRNFNNNDCDEDEEFSDWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT50</accession>
    <name>A0AAD5TT50_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002681</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001902">
        <property type="protein sequence ID" value="KAJ3200452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT50"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="6">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3200452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="87" mass="10165" checksum="F53A119804C1E598" modified="2024-05-29" version="1" fragment="single">SDHINSLIEERVVSDIRCIIFGAGTTFFINTQAFWIAATSVYTYLLIVWKIKLSFGFYEWKLHLFCWGIPLVILILSLIFDQYRADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TT63</accession>
    <name>A0AAD5TT63_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001750">
        <property type="protein sequence ID" value="KAJ3201294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TT63"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3201294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="226" mass="25783" checksum="58E23F1A94470425" modified="2024-05-29" version="1">MVHIPSGIGTPILINNIMIENHSNISSNKEEESYSPYEFESFEKEDLIDIIISRDNKGFNINDYIKKSCNSKDKSSMNINKDDTINYIITPIYDLEPERDTKNTLILLFSITIILLLVFTFIMSPILVTLFPSFTMNGNFLSEGNDLTNYSTYYTLIENNILNSSSLPMDIYSYFYPSWSIEYKTITDIESLAILVYVAFPTALILISIALWTVMIGIISICSPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTN8</accession>
    <name>A0AAD5TTN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-L-isoaspartate(D-aspartate) O-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PCMT1</name>
        <name evidence="8" type="ORF">HK099_001632</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010001480">
        <property type="protein sequence ID" value="KAJ3203077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTN8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3203077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="180" mass="19745" checksum="DC1A665016142A7F" modified="2024-05-29" version="1">MGIGYGATISAPHMHAFCLEAMLDYLKPGNKVLDVGSGSGYLSSCFYQLVKPTGKVFGVEHINELVEFSRKNVLKDHPEFLKESNDEGGIKFLVGDGRKGLKSESPFDAIHVGAAASQFPQDLLDQLNSPGVMIIPVGNSGEDQYLVKYEKDKSAKVTKKNLMGVMYVPLTSKQEQLFER</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTS3</accession>
    <name>A0AAD5TTS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5'-Nucleotidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_001813</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001557">
        <property type="protein sequence ID" value="KAJ3202531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTS3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF48">
        <property type="entry name" value="5'-NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5'-Nucleotidase C-terminal" evidence="4">
        <location>
            <begin position="168"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="410"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3202531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="473" mass="53360" checksum="C5588CF1A25BD594" modified="2024-05-29" version="1">MTKKLRLATIPHMPEVFFKDFIEVGTDLSNELKSEPHNCDLVVALTHMRLPNDVLLSQKVPNIDLVLGGHDHFYKIEGNDVDEYKPNFFKGDIRVVKSGCDFKEFSFITLETDELKKKNVVSVEHVLITKDLPENEKVKEIVNESVGDYFRKLDKPICDSLVMLEARSEICRQQECNIGNFAADICRYAYDADIGFLVGGAIRSDSTYGPGLITIRDFMDIFPFDDQVVIVKLKGKDVLGVLEHSLSAYPKSEGRFPQVSGIQLIFNSAKEPYSRVVSVNFLKTSEEGKALEKTPLDEEKIYTVVTRGYLYKGGDGFSNFCNGEKVGNSKGMILSGLIRRFLTGLQVVQKINSTASNISLEPKKKKPKTEIGVAPNSVTDNLKEKNKKLWKNIVETNLIQKFNNVKEKNSSCIKDPLDSDDSETSDGEKKDVSQKKVKIDYKHLDQKKKDSFKVFLPTIIPLTENRIVDINKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUA1</accession>
    <name>A0AAD5TUA1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'-phosphate/5'-hydroxy nucleic acid ligase</fullName>
            <ecNumber evidence="1">6.5.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001526</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:68076"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.8" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010001432">
        <property type="protein sequence ID" value="KAJ3203427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUA1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170057">
        <property type="term" value="F:RNA ligase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="entry name" value="tRNA-splicing ligase RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017510">
        <property type="entry name" value="RtcB2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03073">
        <property type="entry name" value="release_rtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118:SF1">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="Hypothetical protein PH1602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="8">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="97"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="200"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="257"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3203427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="346" mass="38725" checksum="492881F89EDB2BD1" modified="2024-05-29" version="1" fragment="single">AVFATRGYIYPPLIGGDIGCGMSLTELKTLKSSKLDQDKISNKLRGIEGKNIAKLLLKKIKKKGPYESELLKNYMEEHPSIVSSNFNDNLGTIGGGNHFCEIVTVEKIVDEGIFLEKSLNEESVFLLTHSGSRGLGQSILDEFSKSVSLKVGSEECNRYLEKHDEAVEWGIKNRELIGRRVLECLNICKEDTSLILDVCHNAVVSKTFKDLNERYLHRKGAAPGDKGLIVIPGSRGAFSYLVLPYGDQEENCFSLAHGAGRKWSRNQVATKLRQKYGKSSKAHSVRNYLALTRTRFGNSVICEDKDLLLEEAPMAYKEIEDVIEDLSEFVKVVAILKPFITYKTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVR9</accession>
    <name>A0AAD5TVR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000837">
        <property type="protein sequence ID" value="KAJ3211387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3211387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="55" mass="6341" checksum="F06CDCF7F30AA65A" modified="2024-05-29" version="1" fragment="single">RNQSVFHELKKQDQKTNCKEKDSRTGSKQSFAVQRIVRNEGGKDDEDQFKGIVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW32</accession>
    <name>A0AAD5TW32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001753</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001528">
        <property type="protein sequence ID" value="KAJ3202733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW32"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3202733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="86" mass="9833" checksum="DE36FC138043CBB6" modified="2024-05-29" version="1">MDLFIQKIKVVKIKDYFDDFEVDNLEGQNTKVCRIFFEKKFRQAADNVISSIHYTTSTDSKLIRKVINSVMCLLLEGAVSSIGLVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWQ2</accession>
    <name>A0AAD5TWQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phenylalanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HK099_007360</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000703">
        <property type="protein sequence ID" value="KAJ3213503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWQ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.380:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000053">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="entry name" value="Ferrodoxin-fold anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00469">
        <property type="entry name" value="pheS_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="Anticodon-binding domain of PheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="15">
        <location>
            <begin position="77"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="16">
        <location>
            <begin position="345"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00073229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3213503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="443" mass="51651" checksum="6B898FB37AFAAB37" modified="2024-05-29" version="1">MIMSVMKIRFSRRLNFNKLFLNFSTNVKSVNSSESGHYIQICNEKYKTDQFNNLSTSILQKINVKLLKNENHPLTILKSLIEDHFEKNFKNQYMAVDNLLNPVVTAKQNFDDLFIHKNHPGRAPTDTYYINENQLLRTHTSAHQREVLSSKLSDGYLISADVYRRDEIDVSHYPVFHQMEGIKLFSKSNLTEESKIQNSVTKFNIKEEKKGGPIQTCHDLNECDLVVNNLKKSLEGLIKELFKNEDENLQIRWIEAFFPFTSPSWEMEVLFRGKWLELCGCGVIQQEILNKTGNGDKVGWAFGLGLERIAMVLFNIPDIRLFWSQDERFLSQFKKGQITQFQSFSKYPSCYKDISFWLGKNKSDTNVNVHDNEIFDVVRDAAGDLAEDVKLIDEFTHPKTGRKSKCYRINYCSLNRTFTNAEVDEIQNKVKDIMLKRFDIELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWU9</accession>
    <name>A0AAD5TWU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001069">
        <property type="protein sequence ID" value="KAJ3207245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWU9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3207245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="85" mass="9616" checksum="A2142A95E6DA4FEA" modified="2024-05-29" version="1" fragment="single">KWENPLMGWTSSLMCIGAKLDGMVLTFEQLEKLRKDFPRGIEGLREELLGLLDSSSRGLINILEDGPNKVAMLLEQRSRDLNVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TX03</accession>
    <name>A0AAD5TX03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Eukaryotic translation initiation factor 2 subunit gamma</fullName>
            <ecNumber evidence="2">3.6.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_000175</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010001025">
        <property type="protein sequence ID" value="KAJ3207880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TX03"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01888">
        <property type="entry name" value="eIF2_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03688">
        <property type="entry name" value="eIF2_gamma_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15490">
        <property type="entry name" value="eIF2_gamma_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000009">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000011">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000065">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050543">
        <property type="entry name" value="eIF2G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015256">
        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044127">
        <property type="entry name" value="eIF2g_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044128">
        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003077">
        <property type="entry name" value="PRK04000.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="25"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3207880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="453" mass="49242" checksum="5CA9C3F19ECA5D57" modified="2024-05-29" version="1" fragment="single">MSSKATKTIDPTKLNARSYEVISKQATINIGTIGHVAHGKSTVVKAISGVQTVRFKNELERNITIKLGYANAKIFKCDNKACPRPGCYKSTKSDKEEGFPCERVGCLGKMKLERHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTGEHLAAIEIMKLKDIIILQNKIDLIKETAAEEHYQSILNFVKDTVADGAPIIPISAQLKYNIDAVNEYICKSIPVPLRDFSANPKLIVIRSFDVNKPGSDIHDLKGGVAGGSILCGVLKIGDEIEVRPGIILKDSEGKIKCRPIFSRIVSLLAENNQLQFAVPGGLIGVGTKVDPTLCRADRLVGQVLGSVGKLPEIYTELEVNYFLLYRLLGVRIDDKKQTKVSKLTKGEVLMVNIGSTSTGGRVLSVKADMAKIMLTGLACTELGERVALSRRIEKHWRLIGWGTIRRGSTIDPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXA9</accession>
    <name>A0AAD5TXA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002007">
        <property type="protein sequence ID" value="KAJ3199937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXA9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3199937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="196" mass="22688" checksum="9596964CC56A1030" modified="2024-05-29" version="1" fragment="single">MSSQRSPTNRNEFLAQLLTCLSDDEKNDFESNYQAEVKVEQDEGASVAVKEETENLEFNLKENLKETVTKKENIDVNTNQLLILLNLREKEVKRLQLQNQQLFDQLKVSEPEPNRIPETSKVSAITGAMEKNIIQMVFDLSAVIPKINSKFTNNEVFNHLEHFDTYINTAKEHSLYHDRLCLMSSYNKLAEIHQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXG3</accession>
    <name>A0AAD5TXG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylinositol-4-phosphate 5-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MSS4_2</name>
        <name evidence="4" type="ORF">HK099_006831</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000613">
        <property type="protein sequence ID" value="KAJ3214530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXG3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="3">
        <location>
            <begin position="256"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3214530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="666" mass="75430" checksum="F35E8BBD9EFBCFA6" modified="2024-05-29" version="1">MSKKNDDIHCIPESDISVDNLAIMKIALQRNVLDDASQIKVGFLQKDVPSVTSTKTLSLERKDSTDKKALITSNENRFIANLKRVASLPTPPVEPNVVNNSFFPSLILENNNEILENVGSQRCKDDNILLSVNTPKRTTKARTRSKSSTNAMHKASYGLKFKKSADNIDDTLSLPVLYPESGINSDNGSSRSSVPSVPPNSKPSNEQVECSSVNSITKRPPSAKSKIFTTFLKGGSKNSSSVFTNEKEVVVGTPVKEGHSNYLLMFDMLSGIRISVSRSSSRVQTHLTDDDFIQSHKVAFDGTGQEVTPKTNYDFKFKDYAPWIFKTIRDVFHVESGDYLNSLTGKYVLSELGSPGKSGSFFYFSADYRFIIKTIHHSEHKFMRKILRNYYEHVKSNPNTLLSRIFGLHRVKLPGNKKIHFVVMGNVFPAHKDIHETYDLKGSTVGRIYDEEEALKNPAAVLKDLNWINRKQNIQFGAIKRSVLVAQIEKDVKYLQENRIMDYSLLVGIHDMVKGNKELIREKSLQVVDEPEIQEELHISHKKNPLKKNGKQMKRIRTVSEPSLLSPNNSKLSNNLPPERKFCQFYQDFGGYQATDASDGIRPIIYYIGIIDIFTEYNAIKKFEHFCRSLQYDETNISSVNPKFYGERFLAFMKNSISDKNPAFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXN7</accession>
    <name>A0AAD5TXN7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006419</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000550">
        <property type="protein sequence ID" value="KAJ3215359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXN7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="2">
        <location>
            <begin position="143"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3215359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="471" mass="53902" checksum="58B8E77A98996C41" modified="2024-05-29" version="1">MDLKNLDYREKDYIRTKIELKNITLLEVESKENFQEIRDLLKKGNVIVWAYYIPEESPLIHTPSFNIPIPLTYLDCILSGCLKISKNFARQFILNTEGWSHLLDDRTAHPSLQKYALALDLNERGPCIHQKRDIDSLLKELLADFVESRLIAGHTNSGKSNFIKTIYHTLDVKKLHFPENVEESEDIFPDEFITSCTPLLAKIEFLPATSNEKILLKLIDSPGLPIPVAINKRLKNKEDFTDLANSYVLAVTKFVESQYEATLLEESKVKRNAKAPDYQIHACIYLLDASVVESCGGLTPIDRIVLTKLTQILNVIPCIGKADLISTKHLSNLKKLVMKDIVHHQIPIQTFQEPLSDSEDDELSDTLQGANTSNEYAELLPFAIINGEEEDFFENNDGVVKRWTLERNFPWGTASVENPEHCDFVKLNEALFGTFCQELKDITREVYYEQWRTQKLLEVRGSVINDTMNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXZ0</accession>
    <name>A0AAD5TXZ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_006830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FUN14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000612">
        <property type="protein sequence ID" value="KAJ3214554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXZ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007014">
        <property type="entry name" value="FUN14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21346">
        <property type="entry name" value="FUN14 DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21346:SF10">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04930">
        <property type="entry name" value="FUN14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3214554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="15516" checksum="753C90CB6042E22B" modified="2024-05-29" version="1">MSYLITGLVKFVYVIFNSQNVRKVDSFSTRSTNGKDSLKPNYISTEAASGPEISFATILGFASKKMAKGTAFIVGLGFIGFQTLAHAVIKINWPRVEGVFMRRLDQNNDGKVDSGDVKLLGTRFLHNMTNDLPCTVGFTAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY25</accession>
    <name>A0AAD5TY25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001585">
        <property type="protein sequence ID" value="KAJ3202345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY25"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3202345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="317" mass="37205" checksum="6B0B7EB1FB2FA1A4" modified="2024-05-29" version="1" fragment="single">MMNDERDDFLPSSTEFFDHYLNFDWSSEQIEFLKKVGNEFFYEQDYFLPNISNQAEIRKILSLKTLSKIKDSSNTEKLPFHLEPSNFEIYLNQFIETNFSEIQIEQLKESNSVGSLYCTAEKEKLLSLKRSSNDSKEDENSSFNLKKIKIDNNCLDMENNNSNNNTNETKNIEDGKDSKDSLISKTKMNAMESLNCGTFTKSYPNYTKKSLAIQQLNEKRSELKLNLNSRRKLFQLQLKKMKLSKYNNTSLNDCFYQQQEEDMEYTKNNNNNNSAAAALEEEENLDFEVDDFACFNFCENDLNLNINQIEILNQRYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYD9</accession>
    <name>A0AAD5TYD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH-ubiquinone oxidoreductase chain 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NADH dehydrogenase subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_006016</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000499">
        <property type="protein sequence ID" value="KAJ3216091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYD9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22773">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:quinone oxidoreductase/Mrp antiporter transmembrane" evidence="10">
        <location>
            <begin position="43"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3216091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="320" mass="35101" checksum="3E3B34426D2556FC" modified="2024-05-29" version="1">MFKLSAAPFHQWAPDLYDSLPTPIAMYLIGYSCKGDSGDISFMVPGIFKMNPYLVAALAIILFSLAGIPPLAGFFAKLQVIHSIVNDYHIMISLIVILASVISTTCYLLLIKGIFSVISIEFLYSFGVSISLMSTPPNQTIITEEPKTPPRHRQPDMPWLSDVKPTRVVYPELPAPEPNQPEPVFLNIGKDQTVSTPDLTIQNFLTNRPNLTVQTNFEVNPRLNRYIDLPITPSTPSTDGGSDITLVNELGTPSLPPTPNSITSSNHSTLTNESDLIPNAFLPTEEIRNAVMNFSIRGANSPLVSRQLYALPPIPPRDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYK0</accession>
    <name>A0AAD5TYK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_006176</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000517">
        <property type="protein sequence ID" value="KAJ3215832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYK0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF3">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3215832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="292" mass="32743" checksum="4C4BF0A8F60E63C0" modified="2024-05-29" version="1">MGVFVPVVGSINLPAIGIGTFQLKGENLRTAILEGVKTGYRLIDTAEVYRNEEEIGVILNEVFNTGLCSREEMWITTKISPKSQGYEKAYKSIQNSLKNLNLKYLNLVLIHWPGAANIAVTNLRNAELRKETYQAMIKAKDEGLIKFIGVSNFNENHLTKLIDAFPRSVPTVNQIEVHIQLPQLSLIEFCKKRGITVQGYSTLGQGKLLNGSISIPTVEYIAKTKNMTIAQVLLRYSIQQGIPVIPKMSSKERVLENFNCLTFKFTKEEMALLSSIELDGETRFTWDPNSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYM0</accession>
    <name>A0AAD5TYM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007751</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000781">
        <property type="protein sequence ID" value="KAJ3212371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYM0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16461">
        <property type="entry name" value="RING-H2_EL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47662:SF2">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL57-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47662">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="767"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="576"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="604"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="632"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3212371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="868" mass="94895" checksum="617C0468952AA5C2" modified="2024-05-29" version="1" fragment="single">MDSNAASNFTDSNQPSLKTQLTDSKQSCSSSSSTDNLTTQNYVCEETDSDSVPYINKKSRKSNLKRIPSFLTKRGKSKDNKRSKTLSNHQDDINSNENEESGSNSFMRFIRQSLDIGSSSRSRSSKEEDFRQESVGVEVKTEDHAETSNTELKAEFKSEESIDSNVEVKDDVTTEIDIDANAQFDTSEGISLSSQSSGHATQDLMAIVENEAEPQRTTSTNEGPTSSSVNESQGEMQVQVEVDVEIEIEDEPDHLHNEATEVESNQGGEHLGNVVTEENPDSSADIADSNEPQLTESPLPSLLPGITSRNGGQIFIVGIRSRPLTNRLVGQTTIPTTNENSTTAEVDTVIAPPTIQANNVPSATISIDTDTSPASNVNPPANPEVGGRRTILRSEWMVYVLSNTGLPLTRNALGNPLTTPDLSAIPGLLAEQQDLNQSTPSASTTMSPDLFDTVTQRVRSRSEMRHRARNADVSGILERRRERLNHRLHSRTSMDSLSSTGSENIINRSDMMANDIFGDIFEGIRDRNGEGFPSAESSSDTENPLPSEQRATFPPEIASLFSAMQQRFANPFFPNAETEVRPRTSNTSMNSASESSDASRTSSGEAPTSSTQEAGGGDEFSRFGQLSFPRATDNTAEQRPTDNINESDNEVRENIPTTDNSSTPTQDSGNTNNDLGMNYEQLLRLAELLGPARPRNAQKVDVENQLHTLIYNEEEEELSNGIERLTSKEEECEVTQVEMLTSEDEQKQEKKSKLKIKDLLGSSDKKCLICLSEYEIGDEMGLLECKHGFHKDCLNNWLVGYVNSCPLCRSKGVDSTPDIPQPPPPTAGGIPGGLMQIIQQILSREGLGSGIGGRERGVNQSMGFVMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYW5</accession>
    <name>A0AAD5TYW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DEAD-box type RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SEN1</name>
        <name evidence="10" type="ORF">HK099_005425</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000420">
        <property type="protein sequence ID" value="KAJ3217591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYW5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001147">
        <property type="term" value="F:transcription termination site sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18042">
        <property type="entry name" value="DEXXQc_SETX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056474">
        <property type="entry name" value="SEN1_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23576">
        <property type="entry name" value="SEN1_barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase SEN1 beta-barrel" evidence="9">
        <location>
            <begin position="490"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="7">
        <location>
            <begin position="644"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="8">
        <location>
            <begin position="962"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="817"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3217591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1218" mass="137724" checksum="481A4C4BD5909B82" modified="2024-05-29" version="1">MPYFREESVKMISALLAFSKIYPGEFWTSLVRLLEIFNKNCSFEETPFMLPFIKHMTSIIGEILCILYTVDEGESHKGLNLPKLWVETWTFINHVLQSSAIWAKKSKDARHLVKNFLPEIFAFTSFLLDVDLPKYTAGDDFSEDEFSNFLNFPFMLALSSNFPWFSTHDDRLRLESVDLCCRMLRFAAKVEDWEIPQEIIDQVGKFADKTIATPLQDRERERLLNWDNLDVSDFAEEELLIVDNMKVDNDIKRDNDVVGRELVDIMDVDSELKKAPEEKSDIVEEKNILNEKTTVNKEAVQPIVENKISKKDTMLAWQMMAKAKKQNQSSKKPGLKSSIMKQLRNDVIAESRRIQLKPAVNSYKGYDQSFEVTPLSELTEFEVSRPKRTMQKIDLPNATLHPSQVRIQNMQQPKIKALGDISSLHKQLLLWTFPPQGKNIFPPGFDKDSLKVIPKSFENTREYATVFEPLMVLECWEQFCHAKDEVRKSDAVLTSISEVNAVDGFYDIVFNADAALVRMRNISDHDLVQICEVKNSDINVAIGTLPILAKINSSFCKKDSCTITARIFPSTRRPDIIPRLRPGSSWSLLRLISLITAHREYTAMLNLPMVPLSSQIMNPGKVVLGSGYKINSKNVKELTKKFDINEPQASAVDACVGQKSGFVLIQAEIGPPGTGKTKTIMTIIGSLLTHSTSLNASTSGKGTIIQVPVRTRATKPSIGDNSVVGNKKRLLCCAPSNAACDELVRRLRDGVQDYSGKKRFVPNVVRMGTLKSVHEDVKDLCLELLVEAKFMEAKEFQHFLKSTTVASAKEKSNLQQMEKINRERDNLNDLLVSAQSGLEISEISNKLRDLNDKRKDLMREIFEEKSKKAENKNSLDSVKIKVKQRILSEADVIVSTLSSAGHDTLLNAKLEFPTVIIDEACQSIELSGIIPLKYGAKKCILVGDPNQLPPTVLSNLGKEYQYEQSLFQRIMLSIPNQVHLLSIQYRMHPMISSFPSKLFYESKLIDGGGLMEKRKAEWHDKEVLSPYRFFNVKGTEQKKSGGKSVYNLAEIDAIVSLINYLCISYPGVNFAHRIGVITPYKLQYFKIRDRLVELGGERILKVIDLNTVDGFQGQEKDIIILSCVRGGIDKGIGFLGDVRRMNVAFTRAKCSLFVVGNAEALKTNEQWRVFVEDAVARNVLSKWNETTLSNYNNFNFFPGNLFGTISLKRCIDKVANGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZF5</accession>
    <name>A0AAD5TZF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HK099_000377</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001089">
        <property type="protein sequence ID" value="KAJ3206944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZF5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06354">
        <property type="entry name" value="PBP1_PrnA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15502">
        <property type="entry name" value="PHD_Phf1p_Phf2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050957">
        <property type="entry name" value="BMP_lipoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34296:SF2">
        <property type="entry name" value="ABC TRANSPORTER GUANOSINE-BINDING PROTEIN NUPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34296">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR PROTEIN MED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="14">
        <location>
            <begin position="589"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="H15" evidence="15">
        <location>
            <begin position="1132"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="322"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="423"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="698"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="869"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="322"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="359"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="427"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="443"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="533"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="869"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3206944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1219" mass="133276" checksum="96C5960AEBB4716F" modified="2024-05-29" version="1" fragment="single">LSTVSNYERQLLNGCKSGLNNAVDYDCEFVSRTKDETLALKTYLEVNSKDVVSVIVFILKTAEDLAPYYPHVLFTCIDTYVPNDAPINMQGVLFAEEELGYMAGAVAGTVSKSKVVGIIAGQPFGALQRFAYGFLKGAKYVCPQCQVLGRWVNDPTWGSEDIGKAQAEEYINQNCDVIFGAAGGMGSHAIKYAASKKVMVIGVDQDEYVSTFNNGTEPGSEYILTSVLKKVPMAVSLVVKSVVENSFKSGNRFFDPIQNMSSNYPHSNPNNKSVGNINQQQQNAPNFYSQQNISQSQPQLQHRVNLTSANPQNFNPNQNMFNGMAFNPNHSNPPIQQPQQNKPLPNPYNNQANNHYMTQSNNNYNSNQSNQRHLSLSNLLNSNNVNSFSTSNSINNQLNVNKFMGQQAPLPVHGIVNQTLVLNKAQQKTRRPKRRRKKMNSDSESEDVTSESELEAIAAEVGTDYSTRKTSTPGTPAVSNPSTPGGTHSEAKVGVSRSGRRVKKPEAYVATMETNLALKKKDDDGEGEGTPRTRQKGRGRPKRSSGGQLKNKGRGIYHSPGGRVYDYELGIPILAPRVLPGASQFADHTTFCSVCTFGDSGLSNRIVLCDGCDAPFHQKCHNPKVSDETAENITLHWYCHRCEGTEKDLNKRKPIIDASHGQIDPNSLPSLNNLNSANVQEPNSKLMLNSNLEDKEISKQLSKPSTTEAAKSENIPTTDDSEELERCLVCTSAIFPNWKKVVQENGINIEEKDFAVPEELRKKGPFQPDEIAKLIIAKLCAKCEAIQGNTVDAAILPVILLQASIRNKELSDFLKEKSNMVNKKFIDQELFAFSAKPRHEINQVHVILPPKPKIGLGLGSLGPKCNLATGTSASNSDKGATLYHPGSPGNDLKRKRGRPNRFDGTLNYSPLVQSVSLNSETDSPINISEPVTQSAPLEENVVATKIEPPNTTVNQQNGVSSLPSPTPQFQYTPQSVVTPLQSPRHTPLQLQNMTPQLQQVAPNPASLVSGQITSSDNKPSYTEKEAIKLIPFTTQKDNTILPPSIDTAANFQNPLNSPLGTNIERGPNSAPSVLGLGDIQPPSLNFMTSPALLSPPTLNQQVSQPLQQNPEILASVYGNSPYINNAPTTSPTISNYEDMLEKAILEILVGEKSLSDSSGVKPVQILQWIENNVKGLGNNFKSNLSIAFKNGVEKKRFLRDNSGGYKVNTEFSKIVDSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZG2</accession>
    <name>A0AAD5TZG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">WD repeat-containing protein 75</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">WDR75</name>
        <name evidence="10" type="ORF">HK099_005033</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000378">
        <property type="protein sequence ID" value="KAJ3218476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZG2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000234">
        <property type="term" value="P:positive regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057644">
        <property type="entry name" value="Beta-prop_WDR75_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23869">
        <property type="entry name" value="Beta-prop_WDR75_1st"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23769">
        <property type="entry name" value="Beta-prop_WDR75_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="50"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="193"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="WD repeat-containing protein 75 second beta-propeller" evidence="9">
        <location>
            <begin position="292"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3218476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="775" mass="87986" checksum="1E29C70BE9E4D23D" modified="2024-05-29" version="1">MINFDLQKTSGGKLGDSNVVFTADNNFFFCSKQNDVKVYSVQTGLVVKNLCGHTDLITSLSLNPNNSLQLFSTSLDGTIKLWDFNDGIQLKTFNLHLPILYFKISKQHKNFLFVVTKKKKSKGMRVAKFNIETLKNEKIVDENLECVGLGLSYDENTLVFATSSKLYCYSLIHKEIKLYCIDVNNDIPVTSVLHWHAHDVYSIAFTSNGTYMLSGGEEGVLVLWQLATNHKDFLPRLGSEILSISVSPDESLFALIHKDNTIRLVSSLNLKIKKSIMGLKYSTISNNKSIGLVVEPRNNNIVLNGPGALQFYNPLSDSHILELEVAPRNKIAKREEKELIHPDITHISFSKDGLWMATIDKRDDEEFQLEVYLKFWSFDPNTQNYTLNTRIDLPHEDTITSLEICPAKTVNNTLLAVTSSLDKNFKIWELDTSKKESGINITFSVIYLSFVVHWKCRSVGFYKTIPALYATFSCDGSILAVSYGQLITLWDPFNNLLQAVLTYPPPTNEIKEMLFSSKGHFLYARSTKSVYVWDLLTCSIIWNLKIDTNGIAIDHQSENFLVYNENCFKIFSPKSSIALVEKNQKKISACKFYKSINDNNSSEIEDCSPVLIMDKNFSLLMFADSNKIEKENQYSELTNGSDISKNKLQITPKKLQEPKNFYSDIYGKMKSFDFEKPTPSKEYNNENYILTSNILPADTPFIDIPSNVLPSPSLLLFPFLDSILKKKVVVSVPDNLEPEVEMKDESKVPDEDEQNDISLTTVNFGEMLKNSVFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZK7</accession>
    <name>A0AAD5TZK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Epoxide hydrolase, soluble (SEH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SEH1</name>
        <name evidence="12" type="ORF">HK099_005971</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000490">
        <property type="protein sequence ID" value="KAJ3216229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZK7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="8" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 10" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="58"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="220"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="339"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="263"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3216229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="372" mass="42101" checksum="B2CFA664844A83AB" modified="2024-05-29" version="1">MLNNLTQITHFSPDHEDLIHDVSYDFYGKRLITCSSDLKIKVFDLNEETGNWDLNDSWRAHDASVLKVGWAHPEYGQLFASCSLDRSIKFWEEQESENRKGGRRWQEKHKIPFKNSITSIKFSPNHQGLRLASISTDGVLRIFEAMDIINLSNWTLTDEFEVTNNLSTNTNNSHGENHYCFTWCHSRSLPPMLAVGCGKENVVKIFRMDLNNKWQAQEVLTGHNDLVLDVTWAPDMGRQSQLIGTACKDHYVRIFKLRQEKVKTSPGKNSSSLLQQQSFHPNAPGSADKNIQNSNIHQNSLPNNLSNSSMTSPPIRGALSNGGGIKKPSKFLVELMSAFNDHESEVWKVEFNILGTILSSSGDDGKVRLWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZM6</accession>
    <name>A0AAD5TZM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000378">
        <property type="protein sequence ID" value="KAJ3218477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZM6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3218477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="170" mass="19567" checksum="5477ED9C94525211" modified="2024-05-29" version="1">MCFAVNNLLFPYRYHVSTFNNINPGTFLTQIFLQNALRKNFQEVQMQQRINSIISQANASVKDKISSEKKLRDIFGSFGNLEISAPSTVSFEEFNNETFLKLEYYIVNTSNFNKGVVIVKGVENEIPSVRLLDPFGKIWFCGRGNSKNDDSNQFKNTEEIVEADFREIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZQ5</accession>
    <name>A0AAD5TZQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GID complex subunit 4, VID24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GID4</name>
        <name evidence="3" type="ORF">HK099_005854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GID4/VID24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000477">
        <property type="protein sequence ID" value="KAJ3216452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZQ5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018618">
        <property type="entry name" value="GID4/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534:SF3">
        <property type="entry name" value="GID COMPLEX SUBUNIT 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09783">
        <property type="entry name" value="Vac_ImportDeg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00061469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3216452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="257" mass="30577" checksum="C7A64470943DE7B0" modified="2024-05-29" version="1">MPSKDDLFVNKKLKTSLNYPFNEEEGEEEIESLKNKKKNLKQLNNRICKSECSSLYAGSRFYGEQKSGRSSYEVSVDLQYVDLNQSFLCGYLHIKGLTEEFPTLCTFFEAEVIGPKHSFLTRKWDADEKIDRDHWSRFSSFKKFDKIFNQDGFKFDFFNSDFVFMRWKEHFLVPDHNIKTISGASFAGFYYICFQKSTNSITGFYYHENSERFQHLTLKHVPERCFGDARDVHHHQYRYKRSSTCLIRQFLTKERFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZT8</accession>
    <name>A0AAD5TZT8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RAS1_2</name>
        <name evidence="4" type="ORF">HK099_005014</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000374">
        <property type="protein sequence ID" value="KAJ3218568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZT8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="213"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="543" mass="61693" checksum="8739A7B8815A616A" modified="2024-05-29" version="1">MLLVNDKGELTHLEVLVFGAAHVGKTALINSFLNSSQPSPNYDPTIEEQHCFYYNKIVLSIQDVGGHPFYSAIWSSAILAADAFLLVYDVGEKRSFDLIWPLYKQIIQLKLTRNVPILLVGNMVDTIVNTRQRQVSSEKAQNFAKILNIPSLETTAKAPHSVSHCFKTLIELAKKTTINLVKEDLVELSYSRRNDVNNLNQSKSVPLLSTTLSSNNSTLVSNSSHSSSENIPRSISKTSKTSLLENEDSNESGKKLNLETEEKNFLNKNHESSIFSFADKTTLEREEKKSENSTAIPTSTIERNKVAKGSFMLEPLPPPAKNSIRGRRDVVFSNWKKFKNKKESDVLDSRLNNQNNTLDKSDFNFLHEIKDSGVFLKSHINLNYAGNQKKINNSKSDLKIRTNLSNIKENIMQNEDYETPQEKELDFEQRLINKSTKAKMIMNLSNSFNSIEEDIVDSIQQESCQYNNKYVANDHSDERNLRNIEENGIYFDEEEEKDFFSSSPIIAEKAYTSNTDLVPGGEQKAKFSIKKMKSLQFIFNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZW2</accession>
    <name>A0AAD5TZW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF642 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000983">
        <property type="protein sequence ID" value="KAJ3208651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZW2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006946">
        <property type="entry name" value="DGR2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04862">
        <property type="entry name" value="DUF642"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042148409" description="DUF642 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="DUF642" evidence="2">
        <location>
            <begin position="40"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3208651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="184" mass="20527" checksum="A40B06BFD673372E" modified="2024-05-29" version="1">MQRINLIFLISLLFATVYSACNTDNLVSNFNFEKFDSLTGSYILSPWKYTVLFNDPHDGELYSYYVRQETPRNQAASLNTPGRTEVFQNVTLNPDKKYTLSFATAANDLCKSATKQATGYFGIGESLYSFTSTKTWEWVSYTFNVDKADNVIRFGSSTSGVDGDDIVESVCGPVIDDVLLTVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U048</accession>
    <name>A0AAD5U048_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_005590</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Probable zinc protease.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000441">
        <property type="protein sequence ID" value="KAJ3217148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U048"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.70.10:FF:000003">
        <property type="entry name" value="Disintegrin and metalloproteinase domain-containing protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13574">
        <property type="entry name" value="Reprolysin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042289014" description="Disintegrin and metalloproteinase domain-containing protein B" evidence="9">
        <location>
            <begin position="21"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1002"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="11">
        <location>
            <begin position="582"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="10">
        <location>
            <begin position="811"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1092"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1099"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="722"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="721"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="725"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="731"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00056552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00074021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3217148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1138" mass="125399" checksum="0E290964DC68F0AD" modified="2024-05-29" version="1">MIVQILYLTTFTFLCAFLNAIKPITVDPAMYQQSPDCLTIWTWLPQIYPRRVTNCCEVQANLQESMPVLLTCDANLRVTKINIGQTYNPASTLARKNWKSTGAGVFNAPLPPYLGNLTELRTFIVGEAFMYGPIPKELSKLTKLEHFSVGNNALSGEIPEGLFSDMVNLISIDLSKNKFTGPVPDSFVNLPNLISVKLSQNKFSGPLPDFSTMTGIAKGPKYNVEDGGFFPVCDFRDLGPNVCLQQENDLSKIPQACYFPTPSPTVCVEKTTKASPTPVYAEIVNPKNEKNSTIAIAAGVCATLVLVIFIYYFSFRIVRKRNERDAAKFRDNNGTNPIRHYDFVLLQNHIPNQFTNLINLQFKAFNQTYTLELEKNKELILHNSTLLIHDHVIDYKGKNKKIVKITNLNGHPNVHPYKGKVLNLNNEPVGWSRIIFHKDPFNYDNHKGLMFEGVFTNSDGMFHISSVENYRISRRFGLDIDIVSPFERDSVHRNTKIIIFKDSNDEASLIATIPPSKMTAQNGCGFEHTEDNKLAIMEYRKLSDTFPSPLFKRQSRNVTATASSCFLPSKKILPMGAAADCTYTAGDSVRALTKILNNWNMASQVYEATFNIQLALIEVKILQSCGNSGSEVLPWNVECSEAFTINDRLSAFSEWRGAIPDATDNAGLWHLMTKCSTGPAVGVAWLSMLCTKNSFQQPGNQWVSGTGVSSVGPTEWKVVTHEIGHNFGAIHDCFSQTCPTSCTDSNSDSCSCCPCSATECDCDGQFLMHPTDDSSKTEFSPCSIRKMCNNLSLSAHSNCLMNPGDLKTISTNICGNGVVENNEDCDCGQNCATDSCCDSNCKFIPPAVCDEANNECCQNCQLKQAGSICRPSLDMCTESQTCDGKVAICNPSTMLSNGVQCTVSGGSRNNSGTTCANGICTSRNLQCLNNVAQGSLRTTKPCPGQEMSCNLACLTESNSCIVLNGNFLDGTPCLGGGFCQGGSCKGSDILKVAQFYFENSPFIAWPIAIALGILALSLLYCFLRSIIDCFRPKKKKYVNGPAPALGNNRVGVNSNYAISQTRWVDPELYNGPIGQNYNPHSNVSSEYQYNPNDFERSENQNLHNQQRHTPNQSTQFSNYGTVPLNYQGNVNSNNFGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U092</accession>
    <name>A0AAD5U092_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000343">
        <property type="protein sequence ID" value="KAJ3219327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U092"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01651">
        <property type="entry name" value="RT_G2_intron"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049030">
        <property type="entry name" value="AI2M-like_HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024937">
        <property type="entry name" value="Domain_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051083">
        <property type="entry name" value="GrpII_Intron_Splice-Mob/Def"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34047">
        <property type="entry name" value="NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34047:SF8">
        <property type="entry name" value="PROTEIN YKFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21368">
        <property type="entry name" value="AI2M-like_HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01348">
        <property type="entry name" value="Intron_maturas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="396" mass="45528" checksum="92EC80AB2C18F86F" modified="2024-05-29" version="1">MTIIKTIQSLKDHSFTFKPSRREFVPKPNGKMRPLGIPSPRDKIVQQVMVMILEALYEPIFTNNSHGFRTGRGTHTALKEINTWKSINWFIEGDIKSYFDTIDHHKLISLIEMRVKDQEFIDLIWKAIRAGYVEVKKSNKTDALVGTPQGSVGINGSAQLSEKLKEEIKIFLKDELKLTMSIEKITKSQDKCLFLGLNIYVPFSRNQNQKTIYKQYSNRIVKSRIAANNINLMIPIQMIIEKLENQSICRIEDYNKGLIIPTGKAAWISLPITEIIIRYNYTSIHTILAAVFKKYGNPIKVKTEDGKKTISLKIKKSFAYPSRFNINQKDPFDIMYYQLRSISNIDKTCTVCGATDNIEMHHIKSLKAQIKGFKDIDKAMKRKQIAVCRSCHAKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0G4</accession>
    <name>A0AAD5U0G4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000487">
        <property type="protein sequence ID" value="KAJ3216262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0G4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="176"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="337" mass="39572" checksum="687D82EEE707DEE6" modified="2024-05-29" version="1">MLANEIVKGENLNNQLEQLKVALESVKKNQASLSLLQNQLVEEKDISQKLKKKLEEIIAKSKAIEQENLLLKSETAALKTERSNFDRKADEFEKNIINLTEENTSYGILIDGFEKEKKTFYTELNELKLKLQESLKTVTELENEIKIKNDKSENDLTREQLESTIRKKSEEYQTNLKREILKLNSKENIIRDLKNENENLIKELNLSQLDFNKILQSKKKLELEIKELNKTIEKQHEKESTIAEGTEKAMNNVKEKDMLHKIKQLEEEVDTTKKTLMVLEIEKKNNEQTIESLKSRLEEEEKNSEELKEKLNSRKNLDYNNSEQKNSIVKVKILFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0N1</accession>
    <name>A0AAD5U0N1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000394">
        <property type="protein sequence ID" value="KAJ3218119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0N1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3218119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="202" mass="22927" checksum="89F10EE152A1A1F1" modified="2024-05-29" version="1" fragment="single">MSSTEDNAVLSSGEKSLNSKESHQIVKLFNNWLSVRSDYIKMLVMAKLGNDYKTKVLIVDPELQGNALDYDFSEKETIERAFRVNEYSLEAVEFGDLQSHRYSSQYKNLMKQKKAATLQNSRKNYAYMIIGLVVKIFSYLFFSVIGNGTGNGAVVQIMEVPNQKGFVMPPVSELLQLINGEIDLKGLEKKLEREQQEKVAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1B1</accession>
    <name>A0AAD5U1B1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat rae1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000271">
        <property type="protein sequence ID" value="KAJ3220823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1B1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000190">
        <property type="entry name" value="Nuclear pore complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="101"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="331" mass="36481" checksum="2CCB39D6BFBA4FA9" modified="2024-05-29" version="1">MFSSSTTPKTSDFEVSSPPTDGISNLVFNGQQDLLSATSWDCQTRIYQVLPNGSTEPKAAIQHEGPSLSSAWSKDGTKLLSVGCDKAGRLMDLNTGQTTQVAAHDAPIKCVRFIDGGNMSNVAVTASWDKTVRYWDLRSQAPISQLLVSSLPERCYTMDVTYPLMVVGTAERHLFLYNLTNPTVVFKQILSPLKWQTRVVSCFPSASGFAIGSVEGRVGIQYVEDKDQSQNFSFKCHREDDKKNVYCVNDISFHPIHGTFSTAGADGTFNFWDKEAKCRLKAFSSIGTPISCTAFNKNGSIFAYAASYDWSKGHGTIFTQYTINIYLSLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1B7</accession>
    <name>A0AAD5U1B7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-MPP</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Inactive zinc metalloprotease alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MAS2</name>
        <name evidence="8" type="ORF">HK099_005193</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000395">
        <property type="protein sequence ID" value="KAJ3218118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1B7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF49">
        <property type="entry name" value="MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="7">
        <location>
            <begin position="512"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="5">
        <location>
            <begin position="512"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3218118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="753" mass="85803" checksum="49966B919FDA4662" modified="2024-05-29" version="1" fragment="single">MISIINKRISLNKIRRLYSSKSYRETKVTTLSNGLRIATQDSPGHFVSIGVFINAGTKYENKNTRGLTHILDRMAFKSTKDLPTSELVNQIETLGGNILAHSTRESIMYQAAVFRHDLEKMVTLFSSIVKNPLFKEEELVQVCEASEFELDELPFKPEVNLPEILHSVAFRSENEELNTYGNFLLCDSKERLKSITSDMLHEYRRTWFTPDRMVLAGVGMEHQLLVELAEKYFSDIPKGTPDIMRTQLQQTMPVKYSGGIKLIDANQLPPSPNPDDIPFTHIHIAFESMSMNDPDIYALATLASLMGGGGSFSAGGPGKGMYTRLYTDVLNRYHWVENCNMVNHSYYDTGLFGISASIPPIVEAHEAIVPILSDQLLLTTHRILPEELDRAKNQLKSNLLMSLESKMVELEDVGRQILVLGKRLDVEDMCLRIDSLTCEDLMRAARRVILGEDLKSTLNFGDESSRHWKRTGNGEPTVVIQGHLFKKDPLYNVERTLRDWVESKSLKKIKKIPRPPNAFMVFRAEQSKIFKGRQTELSGMISMMWRNEKNRDLYFQKAERLRVEHELKYPDYVYRPQKKEKKFIKNTPLPTKKKCNKNSLKSHSMMLTKNTVCFKQEVSTVECIFNQQYLPPTPEIECKILNNTIDTTPAQFGNFVDHLENIENLDFFQYLSSKNDVQEQTIAEVLDLGNLFDDCNNDLLLLSPFQPSQLEVVNYDDIKTLANRGGPLNKANAESPPSSGVRGIGEKTLLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U255</accession>
    <name>A0AAD5U255_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005693</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000457">
        <property type="protein sequence ID" value="KAJ3216865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U255"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="508" mass="59486" checksum="B102207598FC3DF1" modified="2024-05-29" version="1">MDERIQPPEVNIEVVKIEEEQNHASNYIRSQAVQIVKEVKVTVKDKMRMDDSAIVETEVEEDKEADMKRVLNDFDPVDSANIIEVLFNSTKKNLCFLSDLLHILNEGEKGYYISLCTAREILEKYLQVGGAEQNKEPQIIIMDDEQLNTNEKKFTKQLELFKEYIISKESQEKELLMIFEDNFFKLIDDIKAEGNVTSSEINLLKTEPIVNLTRKIANLEKKVDTLVESVKVKSSQRALKLVEKRNHYKMTPLKNVAFDDPWITKQELNFFNNENFKCHLEYLKFYFKIQEKFLHFEKRVINATKEIFMRYAEILKKLKESEDCVPFINWVGSLDAFVQSDVDVSERISNTFISKQTYERTINSRQFYKEEDEELLKISYKLNAYINVGWFKNYWKKANFVVTNSGYLYGYFNHTFTSDVADINNVRPNIVIDLLCCTISVNDNLEIQLIEYRQQSTLMGRRNSLKHLLKSEQVEHLCFFEALSKFINTTTQENLKTSATNLTGASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2C2</accession>
    <name>A0AAD5U2C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PRS5</name>
        <name evidence="14" type="ORF">HK099_002811</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000197">
        <property type="protein sequence ID" value="KAJ3221994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2C2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000007">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000005">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000014">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF36">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="13">
        <location>
            <begin position="5"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3221994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="455" mass="49881" checksum="0668016FE0A40173" modified="2024-05-29" version="1">MRGITVFSGSSHPELSNAICERLGIPLGRCKLSKFSNRETNVEIKESIRDTDVYIIQSGCGHVNDNLMELLIMISACRTASAKKVTAVIPCFPYARQPESNKRGAALSSRIPLADVDKLSQLYDKKKHSTSSRAPSTDVLNKSDSTVPLNLQDSLSSSSVSLKNLKDVSTNSFTELERSSRRVSTISTSQSKIAITTLIPQPITEPELPSPVHSKSSNYKCWTARSGTLIADLLMTAGADHIITMDLHDPQFQGFFSIPVDNLFSQPLFIKYIKEKIPDFKKAVIVSPDAGGAKRATVIADKLNMDFALVHKERRHKTSAQDLQREQLTSPTSTITPETEMMLVGDVAGKSCIIVDDIADTFFTISFAAKLLRDSGATKIYALITHAIMSGDAMDRLRDSDIDEMIVSNSVPQASHIAKSKGLIKTFDVAPLFSEAIRRIHNGESVSFLFDVVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2N0</accession>
    <name>A0AAD5U2N0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000195">
        <property type="protein sequence ID" value="KAJ3222033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2N0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37327">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37327:SF1">
        <property type="entry name" value="MICROTUBULE INTERACTING AND TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3222033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="29417" checksum="AFB5EFCA7C2D8827" modified="2024-05-29" version="1">MDASPSPISTLLKEAVNLATKAVTADANQEYQSSLLYYRKSIITIDLLMMKVDEHKIKGEEILDKNEVKRLFSARGQYLARVEYLFENCKDQEAVKIYNYGRENNIVRTLEATSENSEYKTASKNYNVESPYLFQTNFDAHLLEELVSKNYSEDLPKNFIADPPTEPYQKLFWLLKNLINSIEYGGYVTKKLYVPRQVWFQEGCKLTYLEVKQNSFESIIGLLTKLEHLVNCNSDIDELLSFITVIYFKFFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U311</accession>
    <name>A0AAD5U311_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000487">
        <property type="protein sequence ID" value="KAJ3216265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U311"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372">
        <property type="entry name" value="DAUER UP-REGULATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372:SF11">
        <property type="entry name" value="RE19971P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58113">
        <property type="entry name" value="Apolipoprotein A-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3216265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="743" mass="85460" checksum="39DF8A2D56102571" modified="2024-05-29" version="1">MQNEKTKEELENDARARFLIDSEIIDNIMKENKRRRRNIRYSMGALITLAFVYLFTKTYLWAPAFERDIIKYPEEKSHLRQNAEGKYESAKNYADDLLNGAKDTAKDYAFQAKDSAQGYGNNMADTAKDYAYDAKEKAQGYGNNMADTAKDYAYDAKEKAQGYGNYMADNAKDYAYDAKDKAQGYGKNMKDTAKDYAYDAKERAKGYAYDAKEQAKYYANGAKEYAEDYAEDLRQKIPKHKIEYLKNLLREIPEETKELADDVRDKVPDDKLQYLKSLLQEIPEDTNDFAQNLRKKIPQDKINYMKHLLQKIPEESMNYAEDLKDKIPDDKLQYIKNLMQEIPEDSRQYAQDLNDKIPEDKMGYAKNIGQNLPKGFFRNSLFDWNSRNTPSNEDFSDKTELEFKKFSPPENLKASTGVKEVIINYDGHTEGVVKFEVSEADNVALDIEYRLSSANTDKLFKKLSFNQKIENDQFIVDISVPRREDLNEAGCISDDRHDFSSLRKYFKRKNQECETILADITIHLPKKLNNLVIKSQTKLNIESSKANRKLKLEQLYIETEGQISLNSVIKVEDTVKLYAGSKISLLRFISLKLSQIKSMRNIFFVESKFEELKAESEYGLIYGSLDVFKHLHLLAANGDINISSLRIGKNARVLIQRLSEENGDLSVALENFMGRFSVDTKFGEVSLLGDNIKVVKNIEKGELTRERIVEGTILKGKLLDQRVEIKSNNGDVVLVLLQGEENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U314</accession>
    <name>A0AAD5U314_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000259">
        <property type="protein sequence ID" value="KAJ3220980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U314"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="76" mass="8762" checksum="9C7089F25F263084" modified="2024-05-29" version="1">MNPNKIPIQNRRSRIQKSSSPRGNSRNREAEVYRELRQKDEAQAERDQEVPEEIDLEVQEEVSGAEVQGEDIAEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U321</accession>
    <name>A0AAD5U321_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000324">
        <property type="protein sequence ID" value="KAJ3219873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U321"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="142" mass="16294" checksum="5262859BB6EEC1AB" modified="2024-05-29" version="1">MAAKVFGKNTYPFVKRHLKNVDKGHYPPVVYATKFLGGMNFAFCCLNFIRLYKRITNKLEDTLKNNTEEHAISSSDAEIIFSSGLAHSTQFLLNIESFYNNLMGYGNTNPFIFTSEMKFIFLTDFLISFLNFFTIKKTLIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3A6</accession>
    <name>A0AAD5U3A6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_003541</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000231">
        <property type="protein sequence ID" value="KAJ3221419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3A6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051864">
        <property type="entry name" value="NCF2_NOXA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15175">
        <property type="entry name" value="NEUTROPHIL CYTOSOLIC FACTOR 2, NEUTROPHIL NADPH OXIDASE FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15175:SF0">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN C23A1.17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PB1" evidence="4">
        <location>
            <begin position="337"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3221419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="425" mass="48502" checksum="513ED7E11D36EC6A" modified="2024-05-29" version="1">MSNKTEIGIWDEGVRAFEENDYLRAIEIWKDIADYSKIHFNLAIIFIKEKFWDDAFDALTRAIVCDDYLCVAYYVRAYCYYKCQDFEKCLDDYELCSLKMRSNTVVDYSQLGLQFKLFMSHVIFNKALCYFQLGQDAKGDSELLQAKQYLPQKKDDGNEDFSMIEKALNLGKGSIDYFEPCVISFNIIYKPPAQKVKNTEKVDYLGKSRVVAAANATDTFNGFSGTLIKKQTQIDAVNLPKMQANQPKSEAVKRSATVTISRNGTTVPQRKGSMMGGQSIRENNPQLFLRKGSLGSHTQSSSNYTSTNSSSSKTNNFDNQSVGWSSNGTSTTTSLDKIKVKCHFNDTRMILIPFDCQIENFIDKVKKKFYDQLSENSKLKLKYKDEDDELILITDQEDFVEALNNVGIEWGNFGGNNRFEIWCFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3I5</accession>
    <name>A0AAD5U3I5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein KIN-8B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">KLP-13</name>
        <name evidence="11" type="ORF">HK099_001367</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000138">
        <property type="protein sequence ID" value="KAJ3223232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3I5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000056">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF13">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF19 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="928"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="1"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="639"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="650"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="92"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00068376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3223232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1022" mass="117022" checksum="678490559FA68EED" modified="2024-05-29" version="1">MDEEKDKENRLLEKENVHICARVIDEHTILMTDPIDEYGDDVLRRDRQKERVYNYDYVFSEEVDQEELFHKTTKNLISSVIQGFNATAFAYGATGAGKTYTMLGTESNPGIMALTLRHLFEKVEVENADGNMEVNLSYMEIYNEQIRDLLSGKPEYLDLREDPHRGVIIPGITTFSAESAEDVLSFLHKGNKFRTCESTGANEVSSRSHAILQVVVSHKSVNLKGHRTERFGKLSMIDLAGSERAAETNNRGIRMIEGASINRSLLALANCINALGADGKRGKYVNYRDSKLTRLLKDSLGGNCRTVMIANISPASVHFDETHNTLKYASRARLIKTKLNQQITYKYALQLQQAQSEYGDPKGYKTKSRPMTTSTATSTARRQPRALANISDDVNVSLDGINRSRNTAELEEFVSSLDILFKEHLDIQFKLVECELELNRNSLLLKKYQTDLFKLEKISSNESQYKNNKSFEINWEKIGVKVKFSIDQIKKIMKSLNSVKSKYWAQFSTTGDKINSLHQNIPKSFEKRAKQFLQLYIKAHYMKIENIATKANHNQSDITLNDKDSLIQTLLKQIQCSEQIKKCQHKLLNDNNIKIPLNLRTLYFEYDSIGFDEGHLKINSESSDNVTVSNDMINSEETLSASKESIVDAAPKDQNDESYERRSVPKRFSKSSYDLPQIIGSKKKGFNESGSRKEKGKEINLPELNRKVYNRTVNWNSRQKNSELENSREQTIDDADDDYYFKEKNKKCTHAWSWNKLTGNLQTTSYANINITRGKNFNSKTRLSLGTSCFQAKYIAMNSSRNAILVAKQLRLIPVYLKNSTLHDLTNFKLTSDFIRYFGSKDFVRINLSFLNSQNKRLLFNKFNVETLKSEYGYVDVLGGEVYPFLETRDIPVSKAFVDNIEIDFYYTRDRPRLAIESPKTEGNTISVLGYVGIAVGGLGVFLLFIIVPIFMCFRTQSNPIAKRFTLKRRNSKVSLLMERTINRLNSLTKSRRHSFPPRTYHPKNMAKSSMVPIKEERVLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U545</accession>
    <name>A0AAD5U545_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Beta-amylase</fullName>
            <ecNumber evidence="3 8">3.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CCDC40</name>
        <name evidence="13" type="ORF">HK099_007781</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.2" evidence="3 8"/>
    <dbReference type="EMBL" id="JADGJW010000079">
        <property type="protein sequence ID" value="KAJ3224844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016161">
        <property type="term" value="F:beta-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037386">
        <property type="entry name" value="CCDC40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001554">
        <property type="entry name" value="Glyco_hydro_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018238">
        <property type="entry name" value="Glyco_hydro_14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275:SF8">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01373">
        <property type="entry name" value="Glyco_hydro_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00750">
        <property type="entry name" value="BETAAMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00679">
        <property type="entry name" value="BETA_AMYLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042075854" description="Beta-amylase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-activated protein kinase glycogen-binding" evidence="12">
        <location>
            <begin position="35"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="11">
        <location>
            <begin position="565"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1024"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1206"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1353"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1484"/>
            <end position="1511"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1537"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1670"/>
            <end position="1711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3224844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1796" mass="204078" checksum="878CD8923D613EE9" modified="2024-05-29" version="1">MVFKIAVTVLITLNLVLAQGFPATAITLNNPVSANAKSVFLTGDFDNWSGRTIAMTLANKWTATVNIDRTVDHQYKFVVDGKWTLDADAPKIGDGRGNTNNFLKAEPYLSTTVISSTTTVSSTSTSSSTVIPTPTNVVRTYRAEALGPLEKITDFGKFNNDLQIAKAAGVEAFATDIWWGFVETYDQVFDWSYYDQVSAAVINAGLKWIPIMSTHQCGGYNQPCDIPVPAFTGLSSKPEYQYFDIYGTAIAEAFSPWSGDYPIKQYSEFYSAFATQYARYNSSIVRIDLSGGASGELRYPSYTKNWKYPARGQIQAYGTAAVSSFRNWVLKKYGNLAAINSAWGSSLNNINQITPPCDTLTQPTTFGPCANAPISDTFFKTGYKSNYGVDFGNWYQGSLIDYSAQLSSIAHEAFGNIFPKAHIAMKISGVHWQYSNQVEPRSAEKCAGYWDYSVLLKAMKSQDLETTFTAIERDDVPGAPEYSGAHSLPIEFFGLCDKIGAKCGGENALEIFDAGGNPYSNMREILTNFKVLSLTFLRFNYLVNNLDNIQGFSTYVSTIVPEKQAIFFKVANVNVGQNQRVAIVGNVPTFGSGNTQNGFLLQKYCENNQCFWIGTAKVPITEGNQINISLFITNGGSRQCGSFQVNLNTKSTMISVNQGVSDSQHNGIRYISVESNDNNEMKNMQESINENISQTSPPEIENNEDVSSEVLVDSLKADTENIPLTINEESIEKAAFIEEKVTADYKNSTDYNDTTDYKDSADFKVTTEFNDSANEKVSDESNLINVFSTSTFVEESNRKPQTAKTETEVLQNSDLKDILDSITLKPDAAEDKTLDFGITINDSELMEDIGNEVNLKNSLPELPLKSITPKRVETTEKNFTEPHLPVISRPHTSDEDLLLELKKESIAQQINQGEQEINERLLKIRENVDAQEEVEEDEEGDDDALLDPNHPLMSRVQDALYKQLSEQNVKLDLDIKEKEESVKKVIKKREDIGVELYSVQQQLARLQSILEGTEQSSSQMIGFKEEAERKKRLLNSRQKEQTDKWNSHNKNLEQHKNELEKMQQTLKQVKLYSDELASKIMVAKRTTLKSEADIIKQEMEKKRQDYHIDNLTEQLRKLQEQRALYETQFVAQQQETKAALETLQDASVEMEAIQYEKRQLLHQWKSSLIGLQRRDEVLEQIKDGIKTNNNQIINLKGEISGFKLMLKKAAEESEALTLLMNKLDGEVNMLKRQINSVNDSKDKLKESYSVFSKSLSQTEQELAQVLQERQVLQLEVNALQKSTQKTMLQTQKLENEVNEQLQSQVSIEKGTVGTKKDSKKLFQLVHEKESLIALTQNDLSLVKLDSLNISLRLSQMKENLKKLDNDLSKKNESIEKYELEIRRRNDELGKKQSEMDLLNKKYDQLTGKNQDDSMGPLEATIHNVTKSIEAREKECTQLSQFWIKAQNELVSLSKKSADLTESTKDFKIRLTVLNRKKMVVESHFDTQIKEIRDHQKNIRQLQNEMVRVNTLLYSQASDHNKLEENNLTLELEYRAKLKTAEMESIQMESNIEHIKEEKEKALVGIIEAERQMMLWEKKIQLAKETQAALDPNIGASEIREMTVEIHRMKLRYSSMLKVQEKMISEMEKSVFRRETISIRTKTKGSGGGQFQLQKNIQDITKKIRQTSFDVSECENETRNLKEEIIKCNSQIEEASEICRKLEDKEMELFNKLEEEATKKSLGTGFTLVFQRQCKRFEDVKEKKYQPLFRDPVVRRVELLRQKEKLERIHEILKKLKNEGSPQLQKLFNAVESYAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5C0</accession>
    <name>A0AAD5U5C0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_007689</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000077">
        <property type="protein sequence ID" value="KAJ3224895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051848">
        <property type="entry name" value="PGIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059">
        <property type="entry name" value="POLYGALACTURONASE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059:SF19">
        <property type="entry name" value="RECEPTOR-LIKE PROTEIN KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="2070"/>
            <end position="2092"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="727"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="680"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="684"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2116" mass="235978" checksum="BC8BCC866C922389" modified="2024-05-29" version="1">MKAESNSNIQPMKLKRFHDRSDLRLYPTQIITTPENGDSAITYQVDTPTFLTDVNSNIYSAIISEVYTTFDGTPTTLYETGIITVVGGKVSTINGIPTNFGGQPTTIFGVSVTINDEPTYIFPFQTFLTTITNNAHTALITAKTTIVEGKTNSVIETGIITVVGGTITTVNGVPTVFGGTPTTIFGLSTNISGEPSLVLPTPPIPGIVIPPLATGTAPNPLPTAAVTSPNGLQSSNNLLLYIGIAILIFFLIALLIFCALHKRKKALKFKNDEEELGPQPGGMLHNSSTRRTIVDRSTSSSSNENSNLISFNNMAIANEPLNIRSSSEDPFYPASENATYGTSFNNNFSDFSASENLVDPELVGGAYFSNFIPFQKKLEKIPSNKTFESNFANASVINDAALASSYLSMQNTSLENDESHDVAKDIIGHYEGATVPESPTSNGTFGEVTSFGNNQVVASISNEKLDMANEDVVNHSNNIANKFEEQNSSDKNELKTVQDYLLPLAVGAVSSAMYAEKEEKSSLSQYEDSNKITKEYNTSSGEVMEVPFSKTRDVKFDPASIPPDSNTTIPQEVDTILSKIDTHDTSTTLQNFTATAIDNNRNIVEAINTDSKDQYFDKEANYFDSKGEDIPIIVSSPSKTTISDFNENKISSNTNYTTSKNIPKNNLSIETKCKNETKRDSNNATALLSPTSSLVSPTSSNEGIKNSYESYVQNQIDEADLSVRVPPPPTDFVAAQPYFPIRPDEIHMQVGDLVGIERIFSDNWARGQNMSQGKKRGLFPLSILTPIKSGPSQNVVKSKVSIFGGSLTAKTSNSRKNSSEVRYSEKRKTNVIPVRTTSLPGNETLKEIEILPDLSNSVKKNKFLSRSNSIKTIGTVKSKASINSITPSKELIVYQDLQDTVWDISQKSRLNFRSFVRRCRMYSKDFDIKVFLENLSNCENIREEAMFKVIKSSGINNLDDRTFNDLLITIGGDDDKNTSMLIFKHLRNALRDLGVDQFLEANVDVATESKYLATSQDFITKVHLMGNSSSFNLPAFVNSCMNINPDFDFRTFLKIMVEKSNNLDNDTIYENMKDCGVLVSKEEYHEIISLLCVQDDIVLEVIKQWIEVVSVVGISRFIETIDTFYDDEEDDMDAIVIESFLTSVACLSSQSTFALREFVTQSLELNSNFNFETFLNYLLLSDTPANDEEFLEIFKNAGLVLDITTYKRLMITLCGDYELRFTIISHLKLLLKQKGVKWFISRIFSTIQERSLTDMEGRSLLTKIYSISSTATFDYRGFLDRCRRYSSTFDIKIFLNELAFLEESVTDANIKELFVLSGWDISDEEYVKVLRELCGNFNLRLKIVEEWKNYLNTNTPKYIFIWLEERESAEFALKQFFLKLQSYGDKVQFNLNEFLLESRKHSNVFELRIFLEILNSNVKSIGEITTAEVVKTFQDSGLNILETEAIQLIVILFKDYNIGLEVLKDMINASKMGISIVREFYIRIRTIGEAVKFDLHSFISVCNTLESSKFNLSKFLGNFVLLEVENLNVLTLLNIFKQSGLENLNEEDYRTIVETLCGDYNSHLSVFREWLITLKECGVDTFVRINFSYITLEGSLNQLDIKTLIKIFFADILSLGGRFNIEKFCLEAKTFNPSFNLKLFLESFGSNSSFDSIFFESKLTELTTVQKESLFLTLFGLKNKNLFNTVQMLFVTLIRTIGVETIIKEIPYILNLKYNSLAEVQVDWILAEIGLENISGSEKVAIFLTLVEDYTKMDEFFHNWGSAIFASEINVYLNSLKVEYPEVRALLSVKLVNAKAGEIDPALYQQSPDCLTFWAWLPQLYPRGVTSCCDITAANKDSFPIIITCDQNLRITKINIGSLYNPALATVKGNWKSLGIGKLNAQLPAYLGNLTELTTFYITEAFLYGQIPKEFSKLTKLKYFSVGYNSLTGDVPEGLFNNMNSLVALDISHNKLSGPIPNSFIGLPSLISIQLGSNQFSGALPDLSTMKSIGTGPKYDVEDGGFTPVCDLNNLGPKSCIAKGEDLSKVPNTCVLPSPSLKVCVAETIKSSPTPIYAEAIQPKKELISEAGKIGIIVSSIILFLVGGYMIGFHIIKRGNRKAALEEEQVKKERIDRSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5E5</accession>
    <name>A0AAD5U5E5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 NT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000075">
        <property type="protein sequence ID" value="KAJ3224972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5E5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039931">
        <property type="entry name" value="EEIG1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019448">
        <property type="entry name" value="NT-C2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456:SF1">
        <property type="entry name" value="C2 NT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21456">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10358">
        <property type="entry name" value="NT-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51840">
        <property type="entry name" value="C2_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 NT-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="153" mass="17477" checksum="7C8E525EC5493AE1" modified="2024-05-29" version="1">MSFFISANRKVTFEIEITIHDLDNLPYISGLFFCKWKGKNLSGSTRRETVGKDHTVRWDHKLATNSTLIIGKDGYLQPNELTLTFRQVTNGIKNENIGQVAVNLSEFAGARSTQRKYLLNHSKVNSFLRITVSMKLIKGHVEYKVYVPCIKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5H8</accession>
    <name>A0AAD5U5H8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L34</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL34_2</name>
        <name evidence="4" type="ORF">HK099_007251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000069">
        <property type="protein sequence ID" value="KAJ3225168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5H8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018065">
        <property type="entry name" value="Ribosomal_eL34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46595">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01145">
        <property type="entry name" value="RIBOSOMAL_L34E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3225168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="122" mass="13763" checksum="988B5A4F3C941BE6" modified="2024-05-29" version="1">MAQRVTYRRRLSYNTKSNKFRVVKTPGGKLNVLYVKKTASAPKCGDCGAELAGIPTLRPKEYMRISKNKKNVTRAYGGSRCGTCVSSRIVRAFLIEEQKIVKKVLKAQQQTETLSKHQKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5K7</accession>
    <name>A0AAD5U5K7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Dynein regulatory complex subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GAS8</name>
        <name evidence="14" type="ORF">HK099_003948</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DRC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000268">
        <property type="protein sequence ID" value="KAJ3220857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5K7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039308">
        <property type="entry name" value="GAS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025593">
        <property type="entry name" value="GAS8_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543:SF0">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13851">
        <property type="entry name" value="GAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Growth arrest-specific protein 8" evidence="13">
        <location>
            <begin position="239"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="45"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="152"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="261"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3220857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="497" mass="58233" checksum="6537E43A29B6F3DD" modified="2024-05-29" version="1">MISSAGSKKKGSAGKKETASSASKKNLTGSAGKKGENGQVDIKANADLDQEIKKCNEELAAEKEERNYFQLERDRINLFWEITKKELEETKAEVLNKDRELEEQEEKHQVEIKVYKQKVKHLLYEYQNNVAHLQTDAERSLQIDQEEHLVREQQLKKDKRFLKLELKEFELAHEDIIKNLKQKNDQEITVMRSEFERRAKELHSKYERKMKMVRDELELKRKNEIHEIEERKNGQINALMKNHDKAFTEIKNYYNDITLNNLALINSLKEQVEEMKKKEERNEKLMADITSENKRLSEPLQAALAECDTLKKQLKHYQKDKMSLQNSKARLKVLEEKHKQLLWEHEVLEQRFTQVQKERDELYENFVDRIMGVQQKSNFKNLILEKKVTSLKESLEKKELQVNEILKATNLDPAALTNLTKRLEEVLEAKNQQIKELQYELCKVTKAHNDMVRVYEAKLTEYSIPVEELGFKPLMVGVNISNVSKTTTGPAGLVSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U657</accession>
    <name>A0AAD5U657_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SigF-like NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000229">
        <property type="protein sequence ID" value="KAJ3221453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U657"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057514">
        <property type="entry name" value="NTF2_SigF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24840">
        <property type="entry name" value="NTF2_SigF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SigF-like NTF2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="334" mass="35887" checksum="0E52501EFBE0D55A" modified="2024-05-29" version="1">MHSLDLNKQKMVIETYYDKDCRLQNPYMILATRTEIVSLFQSLSKQNTELAAEISSIVYDPVQQIATVDLYETINPKALGGLLPVKIHQIIKLQLERSDEPGKQKLLFITDHNETHRAQEYISRVPILGSWYDGSIREAMGKIVLTSSSIIDATGILDYVPSYVDSAIKAAYKASDKVSGIAGEAVGQVKWVVDAGSSKIGNVAGAVGDMSQRAANASGVSTVISAAGSAANTVSNTTSSVLSTAGSAVHSVTDSTYVMMQFARQTAYIVKLKAAEWVETVQKKNVSCYSPTCIAGVRCYSPSCVRNKVEGGFHAGDVVSAVYNTMLSSPSVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U680</accession>
    <name>A0AAD5U680_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000047">
        <property type="protein sequence ID" value="KAJ3225985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U680"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051075">
        <property type="entry name" value="SCF_subunit_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872">
        <property type="entry name" value="UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872:SF9">
        <property type="entry name" value="UBIQUITIN-BINDING SDF UBIQUITIN LIGASE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="59"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3225985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="110" mass="12451" checksum="1F815B509A519D3C" modified="2024-05-29" version="1">MDKTIRMWAIKNAKALKVFKGHVGGVECLQVANNHIFSGSYDKTIRIFCIASEECIQVLSGHTDGIYCLKVFNNFLFSGSGDKSIRVWDIKSVVANKKKYPWWKETALCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6K9</accession>
    <name>A0AAD5U6K9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Septin 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SEPT7_2</name>
        <name evidence="9" type="ORF">HK099_007650</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000076">
        <property type="protein sequence ID" value="KAJ3224930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6K9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032161">
        <property type="term" value="C:cleavage apparatus septin structure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031105">
        <property type="term" value="C:septin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000162">
        <property type="entry name" value="septin-7 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="8">
        <location>
            <begin position="49"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="414" mass="48163" checksum="E8C61918CB8EDFCF" modified="2024-05-29" version="1">MPLEYALQFRGKFPDPGPWKLPRSFSARPSQPLGISDLPVQRLRRSKNKPYFFNIMVVGESGLGKTTFMNTLFNTNLNDDVKGHPKNLSDSGKTLSINPTTYELSEEGVTLHLTVIDTPGFGDSLNRESNFQPIMDYIDNQYDSYLQAERSQEMRRNIKDNRVHALLYFIAPNPGNNDGLKELDSEFLIKLSMKVNVIPVIAKADSLTTEEISLYKRGILKDFEKNDIRVYPTFHAEDRENTEVEKYMPFSVIGSDDFVESNGSRVRGRKYRWGQVEVENPEHCDFVLLRDLLIRTNLQDLIDTTHSTHYAQYRSSRIRSKGRPESFLACDEYYDSRIENAKKSLTEEMQRKEDEMRQMFVSKVREKEASLREREEMLNEKRKGMMEELEKLRRSVEDEEAAINQLQAQRTVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6U0</accession>
    <name>A0AAD5U6U0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="7">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LSB6</name>
        <name evidence="10" type="ORF">HK099_002715</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000192">
        <property type="protein sequence ID" value="KAJ3222100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6U0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039756">
        <property type="entry name" value="Lsb6/PI4K2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="119"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="364"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="571" mass="64857" checksum="CDDBED8E40FC8321" modified="2024-05-29" version="1">MSKLNHLLNKKKSSNKYSKLNSCDSSDNDNLNLLHEYENDISQHNSKESLDSLENDTQMSHCPSIQDLREVDQNIKNVNDSLVKPLNKDYVNPIPPVTPVSTQQFLNIIAEVRLAISEGIYPVRISQGSSGSYFCKDRQGNIVGVFKPKNEEPYGHLNPKAAASYIDRRLQLNVCPRTEIVSLASPSFHYPLKDRKAYRNGVPLPTKIGSFQLFLTGYKDATTFFKEGYEQVLSRSDSSSAIETTPSLTTSLSYNNPANPINWNEETRKEFQMGFERLVVLDYIIRNTDRGSDNWMVRYNGNNQVSVESSTLEVSQVIMTRDNDNKDTVLNISSYETSINVKTESFTESKLTLPSDLANIINHSNSKKSSSPIFSHVTTPASPSNSNNQIPNAQQGLSVEEINENRSDFAVKPVSISVSAIDNGLAFPYKHPDRWRSYPYGWAFLPIARCRFSSSTREQVLHLLTSQEWWRETLEGLERLFRIDPDFSVSMFKKQKAILRGQGYNLVEVLRRSEMDDVGGSPLGLLQRPVVAVFDEEDEDEDGIDGLKNKFKRFSQRFETFNREQPCFSWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6V3</accession>
    <name>A0AAD5U6V3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA/pantothenate metabolism flavoprotein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004877</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000036">
        <property type="protein sequence ID" value="KAJ3226424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6V3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="2">
        <location>
            <begin position="35"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="2">
        <location>
            <begin position="160"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="308" mass="35435" checksum="C4817BE761F0AB9D" modified="2024-05-29" version="1">MDPQEYFESQIPPSNLSEVSERVDSFVNNHFKKRKIVLVTSGGTTVPLENQTVRFLDNFSAGTRGATSAEFFLDAGYAVIFLHRQFSLQPYSRHYSHSKNCFLDYMKINEKGEVHVEQKWNLNMKEVLVKYQNAKKLGTLIMIDFVTVKDYLFTLRSVTKILSKLKKDAMLYLAAAVSDFFVPDKKMVEHKIQSDDGPLDLRLDKVPKILSPLVKEWAPNSFVVSFKLETDESILVKKSKKSLKTYGHHIVIGNILTTRKKQVIFVYPEEDKPILEVTLNEEELKNGTEIESKIIPKLVEGHNMFRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7A0</accession>
    <name>A0AAD5U7A0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRE1</name>
        <name evidence="6" type="ORF">HK099_002934</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000020">
        <property type="protein sequence ID" value="KAJ3227241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7A0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000008">
        <property type="entry name" value="Proteasome subunit beta type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="194" mass="21723" checksum="0EC6E486CAB85D56" modified="2024-05-29" version="1">MEILFGFVGKDYALTASDNTAARSIVVQKRGEDKSRILSKHTLLSYNGEAGDTCQFSDYIAANIKLYEIKNGVALSTAACTKFTRRELANSLRSRNAYQVNLLISGSDPKTGVPSLFWLDHLASANKVNYTAHGYASYFILSTMDLYWHENLTLEEGLGLVKKCLKELKIRFIGNLPDFFIKVVDKNGIREIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7D4</accession>
    <name>A0AAD5U7D4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PAP1_1</name>
        <name evidence="12" type="ORF">HK099_002014</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000163">
        <property type="protein sequence ID" value="KAJ3222704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7D4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) polymerase central" evidence="11">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="10">
        <location>
            <begin position="90"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="272"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3222704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="396" mass="44853" checksum="35740AC6DD5EC369" modified="2024-05-29" version="1">MKMNWPQPVLLKRIQEGPLQVRIWNPQLYPSDKQHKMPIITPAYPSMCATHNVSSSTQAVMTEEFARAAEIADKIMIGTAEWKDLFEQNDFFHKYKNYVYVICSSSNKDTQLKWSGMVESKVRQLVNKLEAIEELEIAHPYIKGFERSFVVNSEEEFHEIAHGKFPDLMGKEGQLIDEDSVAEYEATADDPRRPIFTTTFYIGLKVKSKDKSVSSVATKKMDIGWPSNEFIKLVKLWDKYEEDCMYVYVTPIKGVNLPKDVLGDQPRVLKKKTKSKRTNLASNPDEVINGSKRLKLSSEIGGDDPETPLAISNELIPEEDEQKMGLDDTKTGTKGDEIIPESIVEFESEDIEKEKGIELRKSSPTINIQSSGPVYSGLGSRAAQSKKFGGIKFKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7N8</accession>
    <name>A0AAD5U7N8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000046">
        <property type="protein sequence ID" value="KAJ3226011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7N8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="177" mass="18777" checksum="F70CEE1BFA37BC7D" modified="2024-05-29" version="1">MTKPDNCFTCPKPECRPISECPMCKIAGCDAIRCGNDTVCKIITPENCFNHCPIAECVKLSQLGDDCGNYSDVKKICDTGLTCKLTDISLPEIGGVCVKEAPSCAAVTCLSGSVCEITQKTCVSCPEARCSLPKECVACDMMIPTCDAVDCAEGYQCSVVPPKDCTECAIAQCVPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8F6</accession>
    <name>A0AAD5U8F6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription initiation factor TFIID subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TAF5</name>
        <name evidence="9" type="ORF">HK099_000714</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000118">
        <property type="protein sequence ID" value="KAJ3223758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8F6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08044">
        <property type="entry name" value="TAF5_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007582">
        <property type="entry name" value="TFIID_NTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04494">
        <property type="entry name" value="TFIID_NTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TFIID subunit TAF5 NTD2" evidence="8">
        <location>
            <begin position="63"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="327"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="383"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="425"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="467"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="509"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="551"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3223758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="645" mass="73109" checksum="83AFB872E658857C" modified="2024-05-29" version="1">MSNEDVNMDAAVSVYLRNRGYKEADSMLKQEANLLNSRKTQKNLLDLNIPDLILYSSKDEVRDDPNIYSNFYSLLRNWINESSLDLYKFELRRCLFPIFVYSYLNLVESDHPKEAQTLMKSFEQDHQEQHSQDLEKLSCVLSKNHLVENEFVKEFKSSKYKIRMSRYSFELLLSFLQNNKMMLILRILNEHLAIKVTTDKPRLLNQDESDGGAVDNEVDGIDDDKINLDQEEVKLGTLPADPWLVKELDRCLREGSGFTPQEMPFIAQELQKLKKENPLKDSPKRDSIPLPPPKLLDIQQEIKTLNELRSKIILNNSLKPTICSYTLHNTYENLTCAKFSPSSTLIGGGFSDSLVKVWNVKGVVNPKQPTITMPSDPRTPTKLVGHSGPVYGMGFSPDNNYLISCSEDKTARLWSLLTESNLAVYKGHNYPVWDCEFGPLGVYFATCSHDRTARLWSTDHIYPLRIFVGHLSDVDCVKFHPNNNYLLTGSLDRTLRLWDLQRGHTVRLLSRHNAGVTCCAISPDGRMAASSGEDKVIMIWDLGTGKLIKKMVGHESAVQTLEFSLDGKVLTSGGLDYTVRVWDCKTGDLSNNEAEISGENRTGNPSTTATSNDLLHTFYTKKTPIFDIKYGKNSNILLTVGPFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8G2</accession>
    <name>A0AAD5U8G2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TTC5</name>
        <name evidence="2" type="ORF">HK099_000010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000001">
        <property type="protein sequence ID" value="KAJ3228455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8G2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032076">
        <property type="entry name" value="TTC5_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038645">
        <property type="entry name" value="TTC5_OB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16669">
        <property type="entry name" value="TTC5_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetratricopeptide repeat protein 5 OB fold" evidence="1">
        <location>
            <begin position="341"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3228455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="461" mass="53842" checksum="E3F6030B7D227CEF" modified="2024-05-29" version="1">MPTCIETEFTRTLFTTPSFDFDSHSEELKALVDELYCFRDNFWIDYKKKQTKPEITSQLQNVDFEQIKSQCLKLKQENILNRMLVLTTPPKKRNLSVKRELDFSNNQYSYSFDPTLSQKQKSFYHYIRGKLFNIFGDYNVNAELDLSKSIKYDPLNTDAWNSMGEVYWKKGDLEHAKLCFEGGLREKKTVEGLLNLAMILRVINKGKVELYKGQIEKSLTLSKEAVEMNIEEKNSWYGLGSSYLKKFFDLTRNSKDLMQALTAYNKAIHHYLENYESCFKDLEHSLELDPGGNSRYLLNSISNYLQNFYRGYLKSKEINYDNFKSTLNKITKKNFLNFKNLKKINDLDLGINVDSFISLKLIKEFSEPVNVHRSFICVDLLNSLNTICLTVYDVKYEALTVGDEMLIGNPNLLHINFNFNNKLFNFKSIRADIPLYVSVNEKKLIENDILFTTIGIEIRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8I4</accession>
    <name>A0AAD5U8I4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translational activator of GCN4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GCN1</name>
        <name evidence="6" type="ORF">HK099_000646</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GCN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000116">
        <property type="protein sequence ID" value="KAJ3223816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000096">
        <property type="entry name" value="eIF-2-alpha kinase activator gcn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022716">
        <property type="entry name" value="Gcn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056810">
        <property type="entry name" value="GNC1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057546">
        <property type="entry name" value="HEAT_GCN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056809">
        <property type="entry name" value="HEAT_GCN1_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12074">
        <property type="entry name" value="Gcn1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24993">
        <property type="entry name" value="GNC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23271">
        <property type="entry name" value="HEAT_GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25801">
        <property type="entry name" value="HEAT_GCN1_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24916">
        <property type="entry name" value="HEAT_GCN1_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1502"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1685"/>
            <end position="1723"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1755"/>
            <end position="1983"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="1804"/>
            <end position="1842"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="2148"/>
            <end position="2185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="934"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3223816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="2824" mass="313996" checksum="C363A6D55CD09BFB" modified="2024-05-29" version="1">MSPKEVESDVDEFLSDPEEESSTDDEVEETKETIQKNEEKNLQFEEDDDDFQVSSDIIFDIELPWLDFINQVIFPNINATRKLRTSCLKGVIAKLNKEEIPDNVLVIILQILIKTVFIFTDSKSVNLVFSIFEKLFEIKAAVANCDTFENPFTKVISKLLDREFKSSLLRLEPGLLFRIIAWTTKILNLMLNKQLSLNKFEKLDELVHKLENSQSLRITLELHFQCLDAIAISSNFSTSHFKKAQKVFLKCLKLTYTIYKNFDAESFNKFFQYFFNKYVTQHTSSNTAILGSLVNFKILNFGEGLNELEQSHLFKFFSEALLSSKNIIPHPYLDLFNLFLDNYMNEHVFYSIASNAERLMLRSPEVSLKVTTHLIKHGHFEVSVYFKKNAEHVINLLKFANVTVKNEALLLFKALCENSQDEIVLKYVTELMLKAITAQSSNVDQKLIYYNAFSFLPPSSEVSKTVIEILTVIATKEKDMQSLQISFSHLSRHIKYYSDLATVDSKFISSTLTPLLIKGVSESKHSVRKGFVSCLYGLSSKNAFETLTVSNVLQLAELATKIIDKVQAAGISLVDPKKDTPYLAEAYYCLSWLLRAADWETKFLKKDQIGELLNLKKTLSVLSASHKFLFNEKFFSKLLITEEEHYAFIDVIFLILNDNELFSPFSSDSANFSALSCALCYLAVLSPHKDVREKVHQELQQIVIDKKNSEFLIERVVEVVKVALTPLLQQKSTAEIRIWDDKIIRSSKDLGYRIFRTIQSVVPNFSANNMKKHLPKPVHQKSLLNLIIITCSSVVTESMGNDAWVSLCFRSGYNPKVLIEENASFLFGTWLKSNSASEVGKISSGILAATSLFTSVAPHVVLQSLVTWIAEGLSDNLVSGISASDLQIWKTKEGELCFDPTKKKVGQIEERPKNAEEKWEQDLRKELKLKGQASNKPMVKQSGKSGNGKSDTKQAKIERELIAAQLDKEVKIRKSVQSTFEKITAALDIFDSILSGFKLSFAEDLSEVVDNFMSILTETILKVITREMSLISKNRHLIEDSHLVIFLGRRAIQTYINLGSIADYKLEDLVQKAKPSLPMCILSCLAIREHETDGIPILYARADLQEFAKKIFGSLKSMYSLSSPLRPSSFSYVFPLCRAIILVERKVSTLKNKQVAELTMLASEILLEHCSLGSCIEIPRSEIVKCLVFLLEHYPRLHKTAKEGLLTFCSAVGSSQGEINSITGNPDFASDVILQLLESLLNFEEIVRDSCLQSLQYLQIPEHLSEVFAVKIFVAKHDNFESIKQHAETLWDTWDQNYVIEKRAINDIVDVVVHELTVIRESAGKALCSILKLYPNEISPTLEKLYGLYKTKAAPIVPEYDEYGMLIATSIDKKDEWPARAGIASALNFCSELIQDPVNLFSFFVDSEALGDANEHVRNLMLEAALSSIRQHGKGCVKELLAIFDAYLQKPAQPSETHDRIRENVVILLGTLAQHLDPSDTLIPQVVSKLMETLKTPSEAVQMAVAECLPSLVKLIPKAVVNLIYELLDQLVNAKRYAERRGAAYGLAGVVKGSGVSSLKEFNIMSDLKEYIEDKKNLQKREGALFAYETLSRALGRLFEPYVMQILPVLLNCYGDSSKEVREATHDACKVIMSKLSGHCVKLVLPSLLNGLAVDNWRTKLGSVEVLGSMAFLAPKQLSLSLPQVVPKLTDALADSHSRVQAAAQTALTNFGQVIKNPEIQALVPVMIQALVDPNKKTNSALVALLETAFVHYIDAPSLALIVPILQRGLRERSTEVKKKAAQIMGNMAWLTDQKDLIPYLKSLLPGLKDVLVDPVPEARATAAKALGSMVERMGEDSFPGLVAELLATLKSDTSGVDRSGASQGLSEILSGLGKDRLEGLLPEIILNAGSQKTYVREGFMTLLIYLPATHGASFQPYLVQIIPPILRGLADEYETVRDSALKAAQMVVKNYSTSSIDLLLPELENGLNNENWRIRASSLQLMGDLLYRISGISAVHDEDEEADTTSAEAAKKALVAALGMDRYQSILASIYIIRCDSHGVVRQSSLHVWKSLVNNTPRTLKDILPVLMEELILSLASSSADKRSVAARTLGELVRKMGENILLQIVPLLENGLLSENEDSRQGVCVGMSEIMAAAGKQSVQDFALNCIPGVRKALIDEEPVVREAAAVTFDTLHQHIGSKAIDEILPSLLNELKSGTGSGRQNYALEALKEIMAVRSNVVFPVLIPTLIAKPITVFNARALGSLISVAGHSLNKRLNIILLALVGALEQKDAAVIDVRESLKTLMTSISDDGVDSLMTILNEFISEGTHNQRKAACELASIFFSQNPADHSNYTADWISKLVGLLKIDEANEVDLETVKAAWNALEALTKSISNSELEKFVVPCRRAISLVSEDMEVGETLAGFNLPKGISPIIPIFLQGLMFGSSDIRAQGALGLGDLVKVTSPDSLRSFVTQITGPLIRVIGDRFPATVKGAILQTIGEILNKVPALLKPFLPQLQRTFIKCLFETATSVRDKAARCLSILITMQTRLDPLVIELTQGIRNSEDNGIKEAMLKALFGLMKVLNSSEDRDINSTSKTSIQDLILHILLKSSENDDGLRVWGAKCFGSLCCYLEVAEAETIIKSKILKFDDETSWTYMSGSLLAITEICKQAPDLIKNLKLLDSIVSCVTTTCTKDKLQIVEPSITVMGLLLSHKAYKHEVEKALIPLLISNLTTGSPSEIRRESLVILKEVSKKDFELIEKYLPTLIPATMNCVRDRVIPVKLAAEKALYHALQIGKNDEILQNVIKTCDAVTARSVGDYAKRVLSKFNDTDSDEGSEMVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U8T2</accession>
    <name>A0AAD5U8T2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">E3 ubiquitin-protein ligase HTD2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HECTD2</name>
        <name evidence="1" type="ORF">HK099_000319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000107">
        <property type="protein sequence ID" value="KAJ3224041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U8T2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="294" mass="33983" checksum="27C19374926310BB" modified="2024-05-29" version="1">MSSCSYELINVLENLQKDERNTEKLKNLVYLTFSKVENIINTFTLPKSITGNSTTIDCDLVDQFYHTLMANPYLQYPDHQSLIVPQICYILTKLKPEERLEFQSITNDSVRSTRRPNTSFKSEAPSGKAIAYFQSILALLQMFINIKILTRDDDDNTPAYKDESIVHAAKTLEIFYVLNEISKFVPYYDFYNETIEGTLDMKEDYPRWKGKDGFSFCDCPFLLGTASKAEILKVECLVHMRHELQDSFFRALFIGVNSPYLQIEVRRTQLVGKSTHDLRKQLRVSFVGEEGNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U928</accession>
    <name>A0AAD5U928_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dymeclin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006476</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dymeclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000056">
        <property type="protein sequence ID" value="KAJ3225643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U928"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019142">
        <property type="entry name" value="Dymeclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12895">
        <property type="entry name" value="DYMECLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12895:SF9">
        <property type="entry name" value="DYMECLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09742">
        <property type="entry name" value="Dymeclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0519">Myristate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="642" mass="74032" checksum="911DE92D5A5E115D" modified="2024-05-29" version="1">MDLSSHPNTEKKNNSVIQLENIQSNSTSTEDFDLSNSSELHSLNEIDLKNFNLKEKKSLSKSIKSSNSSKISSPPLPRITTTYNHTPLASNSIHRRFSISTSKGDPNSLEVENPAFITVISPNLESQKANFEYNSTKTVKQKGYSSLVHSLEALTSEEQIDIEDSDYWFSLISIPKMQQPETVFMRHMAYDEDWSNEAYNTLFLVRIFVKYFIDNLNSIEVHEQFEMDRITYQVAPASPTKKSPTSSFSNAAFSNFPDPKFEIDPQVLKDKKLRSEMLLEELFHVLIYADTVSQANYEFYIEAINLLLVLFASQLQKTCDEISAGNYFLDVVLNRLSYFARGTVTRLISNIIDSQYPPNSNGGVLFSAYSYLFTSKKSAESFAPLSQKSCLLILVLANQNISIGKNNYRTVLRTLLDTDVENLEEQSVNDDVLQETTEILRISFRGIYYIICQNIHSEEISLLLYLLLLQNHSFRTYILSRTDPEGLSEGSVDLIVYGDIVALVLEIVNSILTHSLQHNPQLIYAILHKKEMFVQFRLHSRFGDFVENIDMLFDEEHKILPSTEEVLESIAQHSKVWNNQNFKVFQDLKFQYEEEKEYELFFLPYVWSLVYKHSLIYWDETKTKLWLDFNPDGHLKDFSVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9Y5</accession>
    <name>A0AAD5U9Y5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Elongator complex protein 3</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ELP3</name>
        <name evidence="17" type="ORF">HK099_006473</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.3.1.311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 15">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14 15">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ELP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="JADGJW010000056">
        <property type="protein sequence ID" value="KAJ3225640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9Y5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106261">
        <property type="term" value="F:tRNA uridine(34) acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056591">
        <property type="entry name" value="ELP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01211">
        <property type="entry name" value="ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23613">
        <property type="entry name" value="ELP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005669">
        <property type="entry name" value="Hist_AcTrfase_ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01086">
        <property type="entry name" value="elongater_protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 14" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="85"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR005669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR005669-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3225640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="559" mass="63517" checksum="7FC1D3575060C5A2" modified="2024-05-29" version="1">MTHEVNKNKGYKDESSQLLKVCSDIINELILAHKDGREVNVVGLKSKYSRKHKLSGQPKLIDLIAAIPEEYKSVLVSKLRAKPIRTASGIAVVAVMCKPHRCPHIAMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRSRYNPYDQARGRIDQLKSLGHTVDKVEYIVMGGTFMSLSEDYRNWFISNLHDALSGHTSSNIDEAVRFSEQSQTKCIGITIETRPDYCLKPHISQMLKYGCTRLEIGVQSVYEDVARDTNRGHTVRAVCESFQLGKDAGYKIVAHMMPDLPNVGMERDIDQFKEYFENPAFRSDGLKIYPTLVIRGTGLYELWRSGRFKSYTPEALVDLVAKIMALVPPWTRIYRVQRDIPMPLVTSGVEHGNLRELALQRMRDLGSECRDVRTREVGITEIHSKVLPDQVELIRRDYYANGGWETFISYEDPAQDILIGLLRLRKCSHNTFRPELKPTGNFKKFAGRDENGNDLYENIEITNGQCSIVRELHVYGTAVPVHSRDPTRFQHQGFGTLLMEEAERIAREEHNSIKIAVISGKYAYFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UC20</accession>
    <name>A0AAD5UC20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Translocase of outer mitochondrial membrane</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TOM40</name>
        <name evidence="10" type="ORF">HK099_006036</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UC20"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07305">
        <property type="entry name" value="Porin3_Tom40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037930">
        <property type="entry name" value="Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10802">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3228156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="376" mass="41403" checksum="FEDB8B3234E05E9C" modified="2024-05-29" version="1">MEHFSDLFSRFNHYRKRSNLQCPGSFETLHREVKNTLPTLHLIDGAKLDAAAVLGPNFHVTHSLQWGGQEYPPTYHFGANYNTDNYGLSGQLDSKWNLQARAHYNWYLEKALKPDSVKPDGSDVPVSQLPKPSIKTKVDCSLPTVEGHPPMIALEHEHIGQDYSVALKAINPNPFNSPPSYNLKSKNSTITGMYTLSYLQSVSKNLTLGGEFLYQRPTPDQEEPSFNLVGRYIPNPVELPIPSTVPLGSTSPFPLVNPLDPTEIYTASFSPNSGMLHCSYFKKVNQRLDVCCELQSLLTPGIGGSFGRREGIASVGFKLVTVFSQVRGMIDTMGRVSGTADYTLAPGLMFNISGEIDYGKSADGQGRIGLGFQLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS40</accession>
    <name>A0AAD5XS40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_002145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001694">
        <property type="protein sequence ID" value="KAJ3201645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS40"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF30">
        <property type="entry name" value="PHOSPHORYLASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="112"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3201645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="456" mass="53261" checksum="2792317597DC0EB9" modified="2024-05-29" version="1">MIKSLNNQQSFSLHFNNISQKQKPSNLKALNITIPTYYPSPSNSENQNDLPESPIVPSQPRADRLDSAFEFDFNNDKYYLELTDDHTEGMERYARESVRLAVESTKKLTLDYKLTSFLGWGEHGVVLGATRIVDHKPCVIKFIYKKNDQEKSKNTIPDEILLFQNFNHPNILQFVEYFEDDDNFFLVTSRILNYKYDFEIIDEDEIQPWDECISIETISGTESIIRVPLRNGQCDLFSYLEKFQTLSIDQIRKIVFGLVKSIHYLHTELNITHGDIKEENVLINQNTFQSFLTDFGHSKVRVKDKDSNKFLKCESLYGTFEYVPPEFIPNFKKTKKNDNNTNENEVKKNNNTQDCQQNNLIRYESGFEADIWALGILLYSCSTGLLSAKEHSNFFQLCCLNKFDKKCYPIENNYNFAKIKSEEELVDLIKGMLMIDPKERFTINDCLKHKFFENCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU21</accession>
    <name>A0AAD5XU21_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006839</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000615">
        <property type="protein sequence ID" value="KAJ3214504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU21"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033316">
        <property type="term" value="P:meiotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14131">
        <property type="entry name" value="PKc_Mps1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000131">
        <property type="entry name" value="Dual specificity protein kinase TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000224">
        <property type="entry name" value="serine/threonine-protein kinase mph1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027084">
        <property type="entry name" value="Mps1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF21">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="317"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3214504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="632" mass="72260" checksum="292D2AABE86BFE97" modified="2024-05-29" version="1">MNLRLWRKYLTIWKLYSNLGELENSKNNLLTGIRLNAQPIEDLNKALTDLKNKNKLLKSGLNFFDEDKENSFWNWNDVSPALRSSCISNEPFSDKSSSDTSFNESPQNYQGNSSFEATQPISKYNLPNDLVSSIAIKKDSTTNIISSQPDFEASTKISEVENLHKDVAKSNKENVKKHSNEEINSSSLNHDLHSKTKLFTITNSPPMKQMLIKENINPLYEINLIKGSDDSLNIKKYSEDQNPFNYKIDSIEAKENIVSNEELSKRNLSVNNITSDEATIRAAPVLHKLQEQIISLEPFVISSLVDEKSVTINGMQYKKIDIIGKGGSSKVYKIMNEEGKLFALKKVKLKGQEESIIDGYLNEIALLKKMKNNDRIIRLIDYETIKGQVMYMVLEYGEIDLAQLLIKQNSTLSPNFIRMYFEQILRAVHAIHEENIIHSDLKPANFMLVEAELKLIDFGIAKTISNDTTNIHRETQTGTVNYMSPEALNFVETSSQQKYLKLGRSSDVWSIGCILYQFVYGKPPFAHFKNVVQKLQAISNPKHKINFPVINDALLLEVIQSCLQFNPKARPTIPQLLQHPYITGIHHVEFDLKNLNLQNDLKSEELIFNIIKKVFDKERQKSLVLKLIKEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU38</accession>
    <name>A0AAD5XU38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000619">
        <property type="protein sequence ID" value="KAJ3214454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU38"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="60" mass="7063" checksum="DEE6A978900429FA" modified="2024-05-29" version="1" fragment="single">MDEDLINHVLDIENDPIKTSKSLILKFKKFKKIKKKNEIETENLLSEMSNDVEYLLKGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XU45</accession>
    <name>A0AAD5XU45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000595">
        <property type="protein sequence ID" value="KAJ3214738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XU45"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF132">
        <property type="entry name" value="PROTEIN-LYSINE METHYLTRANSFERASE C42C1.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="225" mass="25438" checksum="20A5D778E2E90246" modified="2024-05-29" version="1">MGKNLLQALFENSDTDSDVNEEDYSLVPEQSQCRIGTVDYLTFGNVNFKIVEDTSKGCGGKIWESASVIVNHILHVSKLQPNFFQNKNFLEVGAGTGMAGLVLAQTAANLNQQCCVAITDLEYCLSIIQTNLELNLDENGKKNCLINELKWGLEIPKILDKSYDYILAADCVYLESLFDLLIQTFKDLCPINSKTQIILVSKKRRRADKKFLVKLKKFFYVEEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUX3</accession>
    <name>A0AAD5XUX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000433">
        <property type="protein sequence ID" value="KAJ3217307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUX3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="150" mass="17202" checksum="83382F7710B254D6" modified="2024-05-29" version="1">MNVSYSAYSGIPLGFFVYDLKGKKLILPNCFSYKKEANTNFYFSTQTMKKLIIGTGYLVFWNYFENENKIAGKKCNNQKYNYTDDLVKGDDSLRNEARGSAAVGERLKLLLKQNQTEKGVAVYEILENFFGVLIAFMLKRLKKKKSNLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVF3</accession>
    <name>A0AAD5XVF3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA-ATPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001929">
        <property type="protein sequence ID" value="KAJ3200312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVF3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825:SF1">
        <property type="entry name" value="AAA-ATPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825">
        <property type="entry name" value="CONSERVED PROTEIN, WITH A WEAK D-GALACTARATE DEHYDRATASE/ALTRONATE HYDROLASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3200312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12905" checksum="3F2A3E606ED4A47D" modified="2024-05-29" version="1" fragment="single">LLKSNDTNIYKAVLVGVLRVAKSGFLSDLNNLCVYPMFSDRFSSQFGFHEEEVQTLLQYYPIPPAFNEIKQWYNSYHAGNNISLYNPWSIVNICDKKTLKSYWLETGKKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVJ3</accession>
    <name>A0AAD5XVJ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleolar 27S pre-rRNA processing Urb2/Npa2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000324">
        <property type="protein sequence ID" value="KAJ3219875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052609">
        <property type="entry name" value="Ribosome_Biogenesis_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018849">
        <property type="entry name" value="Urb2/Npa2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682:SF2">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10441">
        <property type="entry name" value="Urb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar 27S pre-rRNA processing Urb2/Npa2 C-terminal" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3219875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1282" mass="146018" checksum="9E80FD4787395E68" modified="2024-05-29" version="1">MPPEFLFYLQLQNLLLLTYKSDDDNFKYIAILGDLLGLLLENEIYKGTNDETSKLVVGSLMQTFAELKPFAELSFETNDFNKISAILKCWEKLLLLDFDIINNNLNHIVSLILMNIEVKPACNEQRFNSFFFNMFTMYRKSRMLDILVKEILAVWNTLSNRTSSKYCSLFQLGAGFSEYASAISFSLSSQVIPIYEILINEIIGYVPLFSKLQNSTTLKKKKKVLCNNDTEIEFRNPTFIIQLFLSTAKSHQNLSTLQITKLHIQFERLYAEYILPIVTYCANTPFFESTVTKALSPALQLHLILAEVDVVYWETKNTKEFLDFVVALDGSLSMVFSLKLRVLLSHVEHCFCINNLSSSSSDLKDIMENVAALLFPNETEVATPGQKRSTVQFYNEFPFSPESWEIIVQYIPILCHFLSQNEQKRVLVTILKCFCEANSEMWTSLKFPCFQLLQSAAFFEIQSLRDLFEDVFSSLVSKNLVKFFHFFKSLDGTYLEISQNIILLIQCKEKNNTSLEKIFQLLKEEKPPLVKLKSSQIEILDILASLVSTFHLFPLASYFSSKEIYRLSRCLFLLEVVVYYFANISEAVCSPVKHIKKYSIIIKLVSFLRKVNCTLSGLSGDNLILLSDPVIPQWFLKTLDTYQLNRNTKEIHRNSLKISTIQTINVAIRVILKKLSLSKTVTSSDLLYKCLKSTVNFIIKDLESSEKTVYTSKIDEIAYKTEISLTAFTPFVELHDKWIDKKKIKKVAVKLSTIIQTVALQSLKEFSNTTFKVDTNEVKKFQYYFNLMEELLLFYKANLEIDFDSFESTLTLFATSLKRIPHYCSLLENNHKVNNYFSILMSNILSTFCKFSVFAKPLSSEIILDLVKLFWMLIEVDQKNEFREVVLENVFEGITILIQYATLDQYLKIITFFDQVYETSKISEQHESIYFAILKFASAIINTNTVNVEKKICKKPVSSVLTKISQIVNFTGSLDVVNGVIDLFTKLFINDGFKINSEEISLILQSILIFAAPSFYQLRIKSGLQQPNREQCEQIFSSITRLLVIIIKQGKDGLLKVIPSFVSVAKSLMHCFRSPSGAYTVASTKQKLENQKHLIVPNGIPKTEEKNLMQDPFAILSCQAPLSPACADSLARVFDSLLYKHHSVKKSQKGEFSDDAGLAMMETSIKPFTKHVLYLVAEYIAIQISDRAILSYSNIFESNIHTIIVEGIYSLLDLLGQNETNYLLSALSQGNGKGGISGTLGTIGSNLQESLGSIGVGKDAARSLFKQLVSDYNTFHKFGGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW12</accession>
    <name>A0AAD5XW12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol-4-phosphate 5-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MSS4_1</name>
        <name evidence="3" type="ORF">HK099_003807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000254">
        <property type="protein sequence ID" value="KAJ3221069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW12"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="2">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3221069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="311" mass="35523" checksum="F0BB88CFC6F6BDBA" modified="2024-05-29" version="1">MSNPNKDIHRIYDLKGSSVGRAVSDAEAANPTSVLKDLNWKKNEESLFFGKKKKDLLMAQLEKDVELLRNLRIMDYSLLIGIHDMIKGNKDNIRDNTLAEFQPDDTIFRQRHKRHSLNKKLSVKRSSTHNDISQLAQANLPAETPIEKKDFLFTSDHGGFQASNSNDEDLPILYYLGIIDIFTVYNTKKKVENFFKGLVQSKMEISAVRPDLYAKRFLNFMEEGIKPVERLTNKEENNENSEKPIIVVQESSATLNAVTIEEKVMVKIESKSCSPDDTDMYSGLKIDDMKKIDILERRSSFILSTVDSITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XW45</accession>
    <name>A0AAD5XW45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000250">
        <property type="protein sequence ID" value="KAJ3221123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XW45"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="76" mass="8723" checksum="5D3535C55DA6214B" modified="2024-05-29" version="1">MNLSDLQRTVRFFGLLIASVLPLHVSLSYKILILLKNGIRSKENTMKKKKIKKQKEEIVTELSTVKFSEITSSVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWD2</accession>
    <name>A0AAD5XWD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000213">
        <property type="protein sequence ID" value="KAJ3221716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWD2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="79" mass="9045" checksum="037A1FD5F5D71745" modified="2024-05-29" version="1">MSAGNQETFFQKLSRKHTENPFVLPAALLDNDKAKFQTSQRFRVASQLMAFAFVVGGFWFHNLPKDENELVAQKKIEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWJ1</accession>
    <name>A0AAD5XWJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_000401</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001095">
        <property type="protein sequence ID" value="KAJ3206849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWJ1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000016">
        <property type="entry name" value="Proprotein convertase subtilisin/kexin type 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042221151" description="Peptidase S8/S53 domain-containing protein" evidence="7">
        <location>
            <begin position="22"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="172"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3206849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="437" mass="47674" checksum="B4B31D14599379AB" modified="2024-05-29" version="1">MLRLLFFVLLTTVLCLPKIVSENQDHGYYIVKVKNHGGLEKRDSLVDISFAEEIIKNDNKNILKIENEEVEIKKNNNFNDDEEKKLKKTVINQSKILHYYKDLPNFQSLAVFVSNKGYQAFESNPNVEYIQRSTNLKLFGTQFDPWWNLNRIDQVDLPYDNKYTYPEQAGLGITVYVLDTGILSDHPEFEGRASEGLSFVNGTISAGAKDLNGHGTHCAGVVASKTYGVAKNATVVGLQVVDQDGKGNDVGLITALNWVAANAIPGKSVVSVSLGSDIKTCVKVARPDHPEDQECNSKAVRDAVSSVVKLNIPVVVAAGNDAMDACEVSPSSEPSAFTVTSSTSSDILSDYSNYGSCVDMIAPGDFIASPYLDNEVVILSGTSMACPHVSGAFAILLSQSNYTSVDLLYKELSSKSTKNKFSFPAPKNTTINNLLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXA0</accession>
    <name>A0AAD5XXA0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">protein xylosyltransferase</fullName>
            <ecNumber evidence="6">2.4.2.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Peptide O-xylosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">HK099_001295</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>UDP-alpha-D-xylose + L-seryl-[protein] = 3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:12567"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132085"/>
            <dbReference type="EC" id="2.4.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; chondroitin sulfate biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Glycan metabolism; heparan sulfate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 14 family. XylT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.26" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000135">
        <property type="protein sequence ID" value="KAJ3223321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXA0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030158">
        <property type="term" value="F:protein xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050650">
        <property type="term" value="P:chondroitin sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015012">
        <property type="term" value="P:heparan sulfate proteoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003406">
        <property type="entry name" value="Glyco_trans_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043538">
        <property type="entry name" value="XYLT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46025:SF3">
        <property type="entry name" value="XYLOSYLTRANSFERASE OXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02485">
        <property type="entry name" value="Branch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="15 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAJ3223321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="455" mass="52631" checksum="F4CFC1D20D66137C" modified="2024-05-29" version="1">MLEKRKTSKRLLIFLLSIYFGYTYFQYFPSYNTQKFKIKSQPVAVKEKVNDDGLKIYNFNYCESFDGSVMNKSIYLNSGSSKYFYSPNPAAGTDIQIQSLTEEDLTQIIDSVAIEICQLMPLHLEFEKINFFSCFTALMGATGFSDISEDPILKELSNSHFYNWIQETPRNEMKSIFKLAYYITINRIEDIPNLKFLISAIYTPETIILIHVDEVSGTLLKILKEYVDILRSEQKSISIKSHGFKIHLKTSSVIKAQLLGFFELYDLGSWDYLINLSANDYPVKSSAGIYQILMQNSDKVWISYDKDEKMKSNLEVPCFAVSCFWGTRRVSKFLDQFPSTKNSPWGFFPRQFIKEIRNSKSLPMLLAWVENSWAPVESFLSILTLSNESAWKNRVINSNKRFKLGKNETFAQLKLEMASENAFFLEDVYINRNIEVKHFADNLQSKSVSQNLVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXC5</accession>
    <name>A0AAD5XXC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DPS1</name>
        <name evidence="15" type="ORF">HK099_005817</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000470">
        <property type="protein sequence ID" value="KAJ3216597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXC5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000132">
        <property type="entry name" value="Aspartyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="312"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="101"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3216597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="606" mass="69564" checksum="BEA576AE43B97E58" modified="2024-05-29" version="1">MKGNSIRSRLFPVVRHHSSYCASTKLNCNNCYLMADLGLQHWSSKIKKTSPHFHFYTNLRFFSLFSKKKKYFSTTTKLSMTEQKEETILGEDGKPLTKSALKKLQKEKEKAAKKKEVADRLAAEKAAREAQNEADCSKDRYGVLPLNQSQERTFVPRAQISELNSSMENQVILMRARIQTSRLTGTKRVFLTLRQRTHTVQAILSVEEGIISKQMLKFVAGISSESLVLLEAKVLKPEELVKSCTLQNVELHITKLHVISASERLPFTMEDASRSEVELENDATLASVKLDTRLNNRVVDLRTSTNQAIFTLQGAICKLFREYLDGKSFTEIHSPKLLGAASEGGANVFKVTYFKTNAFLAQSPQLFKQMTICSDFERVYEIAPVFRAEDSNTHRHLTEFMGLDMEMAIEEHYHEVLDLFDELFVYLFKELKKRYSHELSVVSQQFPFEEFEFLPKSLRLNWKEGIQMLRDAGVEIGDFEDMNTEKERTLGRLVKEKYKTDFYMLDKFPTAIRPFYTMPDAKNPEYSNSFDFFIRGEEVLSGAQRVHDAELLLKRSKEHQIEPHTIQGYLDAFKYGAPPHAGGGIGLERVLMLYLNLGNIRRTVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXR4</accession>
    <name>A0AAD5XXR4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000094">
        <property type="protein sequence ID" value="KAJ3224399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXR4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050872">
        <property type="entry name" value="PPR_P_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128:SF356">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1258" mass="144942" checksum="611BFA0B40CA8ED9" modified="2024-05-29" version="1">MSYPFFPNRYLFLLPKRQQCKCTFQVCSYSTQPRNEHIFAVLDNVFNEGKVKKTFLKSVNFNVSEKYVPKTLSSDSNFTSWLKIASDKNVNEILKFAKIALEDKWDLRDNHFDDLIHQLLGKNQVSCAYSVALLILNYGHPNDEEYLLFTTIQEVYNSLVNLHMIKEALILLRYLSASKYFKIAKQSFETIITHHATILINFLRCENLPSHDVRALKEKEIPKLDKKELETTLETLILDAIKLNLPLNDRAWSLCFKLAFQKGDLVEIQKIKRCFELSNSVTGNNSDIFIFFPMMITAISIFSSRIPTSHQDAIEKEKIAFAMKNMTLEWLSEEKEAKQRNFPPSLEEYMFFETALNLDNHSVRHHMNTLEILQKKYPMQNLKKQLSAFCQSENVVKAVEVYNEITSKFSSPFHENEAVEHLKVKKTDNLQDNHISKILKPFLKRQHQLIETDFLLKRFCLLLNNHEKYKELMLETLSLWRDNIKVKDTDRVKAFYDTVYFLWGSAVLSSNLENFVAILNATIVNGETKSVFSYYFVDVSTIKKSITSLVAYQDDYFFSHKAFIHLIKCGIFPSNSELLHLIRTLAINGQDDLILDVSFALISCGFIPAPQIQSYFVKALTVGGKPIEALSFLSQINSVDMKPSSFEIENIALSIAEKDGLKEFNLNIENLSGLDVGKDEAVRWKLDVKFLSKLLLCSRNIEDVEMVLELADNSPIKKDIHWLNTLILVLCRIKKPEMAEIRAKELISCGIKPNILTYNLLIKGWGRVGLYYRAMRWFNWLRDDVKNRKLPNFNADVHTYESLIYAIMKCPEFDTKKKKEMIRAVLKQTVMTTFSVNTFIQLAIAESDYAGAQQVIQEAAKSNVFPDTVSYLHLIKGAVKSKRLIEVSLLYDELRNGLFNGSIKPDNKRFNPRLQKKAEFAKDIALSTYCSQGTLKEIYFLYTKIYADFGNLKKVESIIDEFRIKENIGPTIRITGNLVVAKFKKLGMENAIRFIQHYAGGATSSKQLSKHSYLWGVLMEELFKRKLFKECLGIPKYVDGLYIDGTMLAIMMKCCLHGKFYNIADEIFYWSLHLNKSNKSATIMEQEEKKMDLVLTKRTPPLNIFSGVEDTLATFCTFYLDCKGFNGKLEEIHEAFNTISSLNVLGRSKVKFSSGFAESKSVSGGKNRWPPETVYSSYIEALIRSNNVESALEIFRNLRHDIHDPVSVAVKPSEKMISNILHLLNVQHYKKYQLLFIQAVDKYFPSMSWAVNKFPSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXR6</accession>
    <name>A0AAD5XXR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000665">
        <property type="protein sequence ID" value="KAJ3213919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3213919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="295" mass="33678" checksum="79E9969C81532336" modified="2024-05-29" version="1">MTTNRIFDLVTKAGKINETLGVLTRVDRFPYDFELSNILNKNAPDYIPLGMGYIAVYNPDRLDKQSLSEWCDKEINFFKVKHPDLVSKNVVGIDGLSQKSTLVECQDILVNYKNTLGRVPLENSEELFWNEMKAYITSTLIGGLFEIDNLKIQEVIAERARVCFQSLTFPPASQANFVNERMEYLKLKLNIEKYLIVYSHQINFEIISLIKNMIVSDSVSTFSTEALKAKNDPNFKPDVMVLTIDNLLIPLEGIINGIAFKKDYLCEGEKYIQIRKTILETSNSITIANEKVLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXR9</accession>
    <name>A0AAD5XXR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXR9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="160" mass="18739" checksum="D89599148F11FD90" modified="2024-05-29" version="1">MHVLNARRKGRALPIGIPLSVKESFLKEESRPTLYTRPIKGSSSNLTFKNVKELERELEELTNDVELLNEEKFNLQKTLKDLETTQMELQQVTEFKKKQVKVFKLELSKFNNENFKNSDSASPQFKNLLNSLLSERQILEKKKMELKRNLESVNREIESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXT2</accession>
    <name>A0AAD5XXT2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000386">
        <property type="protein sequence ID" value="KAJ3218304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXT2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042275241" evidence="3">
        <location>
            <begin position="20"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="341"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="414"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3218304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="562" mass="58943" checksum="CCEF4F49BC221C96" modified="2024-05-29" version="1">MKFLAVLLLSTTTIAAAIGKDSKTSALDPAFSPFDNKVKGNQFTTGPCTKDEECQSACCDGTKCRAPDALKGVETCRDGLAPDFTNGLKFVTKPVSGAGNQGQQQGNGQQQGNGQQQGNQQQGNGQKLGKDSKTSALDPAFSPFDNKIKGDQFTTGPCTKDEECQSACCDGTKCRAPDALKGVETCRDGLAPDFTNGLKFVTKPVSGAGNQGQQQGNGQQQGNGQQQGNQQQGNGQKLGKDSKTSALDPAFSPFDNKIKGDQFTTGPCTKDEECQSACCDGTRCRAPDALKGVETCRDGLAPDFTNGLKFVTKPVSGAGNQGQQQGNDKEVNNNQGAKALADKAKIDLSEDKALAEEAQKKLTDARKNLSADPNNEQLKLAAKIADDACAVADNQVLLDEAMIANAGETNNGGVADLEKALKGAQDQLKVDLENQNKALENKALADKALQDAIANKTAEEVAAAEKVKEEADLAATKAKECAQKSKELVDNKNIKAAAEVPPVADNDNVVAEKENVVEEGEASIIDDKATGNKNLDTAAIQAAFSQLTKSLTELGAIFDNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY15</accession>
    <name>A0AAD5XY15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_006697</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000599">
        <property type="protein sequence ID" value="KAJ3214682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY15"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23649">
        <property type="entry name" value="Khc_CBD_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01369">
        <property type="entry name" value="KISc_KHC_KIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000031">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059182">
        <property type="entry name" value="Khc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 9 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="12">
        <location>
            <begin position="6"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="424"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="501"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="661"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="802"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="87"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3214682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="971" mass="110396" checksum="02186C471B1D781C" modified="2024-05-29" version="1">MESNNNIRVVCRFRPQNKKEINEGGFTTTVFDDDKRTVTIEGREKQQFTFDRVFDWNTSQDVMFEYTASATINDVMKGYNGTIFAYGQTGSGKTHTMMGDMENVTMRGITPNLVEKIFDTILKAPDTLEFTVRVSFMEIYMEKIKDLLFPQNDNLPVHEEKSKGVYVKGLLEVFVSSTSEVFEAMRKGQENRVTAATNMNAESSRSHSIFVIQISQKNLLDGSTRVGKLYLVDLAGSEKIGKTGATGQTLEEAKKINKSLSALGMVINSLTDGKSSHIPYRDSKLTRILQESLGGNSRTTLIINCSPCSSNEAETISTLRFGMRAKTIKNKAKVNADLSPAELKNMLKKIKQDLSALQMYTGSLESELSIWRSGASVAEADRVVFNSNNYSTENLSTSSPIRGSFDMLPLRSQTPITAWTNDDREEFFKRENELADQLEEAESDLKNKIAVIQICNEEINFLKEKEISYVKEKNQLHFAINDLKSEIDNLNFENKDNQIMMDSLTEANNELANEINTLRKKLHDFENKPAENFVKGEVEKRKKEKIAELMGDLNDSNSTVQKIKETLKRLSFESNLNNAPTLPRTEKEIIQQHKELLESKNHVKQQGVLITELVQQIRLAREEYNKISLKKDGVEFKLSGMHTEYESLLNGILKEKNNIDEDKVSNEIEELTLQLEKQYLEKKNIQEEHFLELKNNSSKKDDDLIKFSNNLLNLTNDNAELKKSLEQLKKASSSTALDLQKKEQEFDQMRKNMTQQMLEFDAMKKKLMIDLQNRCEKIVELEISLDENRELVQINKNNSQISKSQQQKMIFLEQNLEQLTAVQKQLVEQNTSLKKEFAIAERKLSNRNDRIIKLESLFQDAQTKLELQSQKFDAQLSSMREKLKEAKTQNGVSQNGWLYAGRIAKPLRGGGGGAGGISGSELDEKNDNLDVVNYMEVDNNAINLPNPTASATLNKTPPGKRSNWYVSLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYJ8</accession>
    <name>A0AAD5XYJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_005938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000488">
        <property type="protein sequence ID" value="KAJ3216256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYJ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3216256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="84" mass="9602" checksum="0BC2E27F2C1F157B" modified="2024-05-29" version="1">MSVEHCRKACINFNVILDNFPISDGNKCYCSVLSFGAIVGVVDHTLFNKDCPGNDEQVKLLMHYIFYKYNLAVKGYAYPIKLQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYT3</accession>
    <name>A0AAD5XYT3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATPdependent RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DHX35</name>
        <name evidence="4" type="ORF">HK099_006929</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000631">
        <property type="protein sequence ID" value="KAJ3214327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYT3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF136">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX35-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="41"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="221"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3214327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="595" mass="66984" checksum="99290D0713D2C1E4" modified="2024-05-29" version="1">MQNKFWKPEEKLPGVNLERGNVDQLVTITQNKKLPITDKSSGKTTQVPVFLHEASWTAGNKSIACTQPNRLATISIANKVASDRNCTIGTEVGYKVRFDHTNNLKSSSTKILFLTDGELFRELLEDPFLNKFSVIILDELHERSIFQDLNLTLIKKVLGKRDDLRVVISSATLDAIKFQKFFNEDKLIKVANEKKVAEILSVEGRHFPVYIQYLMEPCLNYIETLIETVKNIHKFENVGDILVFLSEKDEVEDVVSLLNEISGSLYAVPLYSGLTVQEQLKTLERAPSGNRKVIVSTSVAETSVTIDERLVGVVYVIDSGLTKLKVFDPKSGLESHITTTISKANADQRAGRAGRTRPGKVFRLYTEDTYYKFANNIIPEIQRSNLASAVLSMKALGIENVARFDYISPPPSKLIIHSLELLYSLKAVDDYGRLTIPFGMNIAESPINPMISTMLLSSEKLECGEEALSIAAMLLVQNVFLTPSGYRKEAEKEKIKYSVEEGDHITLLNVFNSFIQSKQSQRYCQQNYLNHKSLNRAYQIRQKLKIFLVNLGIKIKSCKGDTEVIRKCILSGFFSQVAEISNDGSYRSVRDKELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYW4</accession>
    <name>A0AAD5XYW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Lysophospholipid acyltransferase 5</fullName>
            <ecNumber evidence="15">2.3.1.23</ecNumber>
            <ecNumber evidence="16">2.3.1.n6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">LPCAT3</name>
        <name evidence="19" type="ORF">HK099_004412</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="14">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.n6" evidence="16"/>
    <dbReference type="EMBL" id="JADGJW010000031">
        <property type="protein sequence ID" value="KAJ3226668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYW4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047184">
        <property type="term" value="F:1-acylglycerophosphocholine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071617">
        <property type="term" value="F:lysophospholipid acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030258">
        <property type="term" value="P:lipid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049941">
        <property type="entry name" value="LPLAT_7/PORCN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906:SF14">
        <property type="entry name" value="LYSOPHOSPHOLIPID ACYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13906">
        <property type="entry name" value="PORCUPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 19" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="374"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00026120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00038923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00039721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3226668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="524" mass="61338" checksum="EE597E20AC045582" modified="2024-05-29" version="1">MEKLKTNVIDEISLIIGIAEPQLRFLLTILSTYLIAFTYRALLYKKITRYIRILYNLFFSLALIIFFTRGNRMELVILIQPIFFTWLAIKIGGDILNFRKSISSIAAICNFFYLLYCYKKHSTNSYDLNFLTPLSVSSLRLMGLALDYGDFNELIGNEKKPESRINDWQPLLPEKDRGLQEFPSLIETLSFCLYYGTFFVGPQFPYKLYEKFISLELFYLERKKGDKIKGVVLSGSISSAIRQFFIGAFYLAMNEVGNNFMPMTYFESKQFLASSFFFKLGCIVLLGKVGLFKYFGIWKLSEVALIVSGVSYNGYSSVNDKYSWNSLENFRPNIYEKLTNLGDVIVSFNVNTNIWSKIYIFKRLRFLNNKNLSAIATLFFLAIWHGWHIGYFLAFSLEFVDMEAERRWKLIMQKNVDDFIFKEKNNKDIPKKLIKAMYFGFSHVYCTFCLGYALIPFNLLHWEPTKVVWSSVYYIGHLIPLSIFIFSLIVPMSKKHGFEQVQVQHTLIEKKTLKLTRKKNWKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ19</accession>
    <name>A0AAD5XZ19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ19"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="7">
        <location>
            <begin position="245"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="292"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="397"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="432"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="467"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3227611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="706" mass="82285" checksum="9D78874E719B0ECF" modified="2024-05-29" version="1">MNKFNRFSYNNSKNESDQKNLASKNTDSENVTKSDSTKIDTDRVTQLNKNSKDIFEKEDISKIFSSSRNVFKAKRNPKDFGYESKLKKKISYQTESQYKQDEVNFQKDYDGLKKLRRKELNEKKKIEKKLISLLSKSERKRIKREKATRPYPILSLNDQTIMDMLLTKNVCFIANMFQYYKKIIDNGGSFTDTTTSAVLRFIAKRQRPKDLIAIFELLKAPSQFHYLVLFQYFVKVNDTENFEEYYGRFKNSGIPPTQYFFKEMIGTISCHKNFTLLKTIFADMKKQEIEPNAEIYNAILYMCSQTKNDHKIFNYYKEMKTRGFFPSLQGYSNLMLASLKLREFSLLDILFEEMAANCVNPDVTFFKTLIKTAIKMNLTQQIETFYIQMNSKGLPLDFVAYTTLMNAYIKLKQPDKVSGYFNDMISSGITPNTITYNTLINAYIQAEQLDKVDFYFQEMKKKDIKPDIQTYSSLINAYSKTDFDKAKCYLKEMTEVGMPPSMLTYHSLYFSDNHLNIPTLLNRLEEFSKLDIEPTFIIWGSIMNCFSNSGDYVTAFKIFQSLTGTLSESEVPPSLPIPVKNADFKPKYSFDINNFFLTAVTICKENNLKKELEIVWKVISSNDNIPITLKLLSSYFQALCHFEKFKDILKILKNSVKDNEMFTTSNLPKPNKQFFTDLVTLLDENNASFFVPDVLKLEKICLDDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZD2</accession>
    <name>A0AAD5XZD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000352">
        <property type="protein sequence ID" value="KAJ3219111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZD2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3219111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="233" mass="27011" checksum="44D332D0801BFA74" modified="2024-05-29" version="1" fragment="single">VYLESEVRDRLDKLLGYLESQDGVCGNGTMLILGDSCLFSRFSMHETRMILHYNKVRPLGINVLSYTPVFCSGAWQNLYFIRLQNYVLVVMAYMGVNYSRLERKISDFRMSFIQSRLEIPTEAPLILLRLFAKRETLAMLYHNIKTGNTIFPQLRPSPEIQQREILQTFWNFFSDASASLRVPGVTEFSVSKDLYKFYARSEGVHKLYLLLANDSVSMENVAMDVLKNLKNFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZE3</accession>
    <name>A0AAD5XZE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Centrosomal protein of 131 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AZI1</name>
        <name evidence="3" type="ORF">HK099_006041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035735">
        <property type="term" value="P:intraciliary transport involved in cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030465">
        <property type="entry name" value="CEP131"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019176">
        <property type="entry name" value="Cytochrome_B561-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31540">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 131 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31540:SF1">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 131 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09786">
        <property type="entry name" value="CytochromB561_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1068"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1211"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1350"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1550"/>
            <end position="1680"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1707"/>
            <end position="1734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1068"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1082"/>
            <end position="1103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3228161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1737" mass="200036" checksum="384906F0EA9584A0" modified="2024-05-29" version="1">MNPSETRSPFATPIKQQGNQYRIPSHFSPNDLKERDFMNRRSSPLQQLQQDNSNRSPYNNDLSPSIENSTERLVLNKEDPAVSSTKNEKFHFGVWFHPSLNNIWVNQYTFEDKNFGIYNFLSLVLYVYYKCTWETKICQSLSKHLTATKALTINLKKASFICSNAENTRSASYSPKQSSSIEFFVKNSKEVTANQKRNFIKDLVSTEVKSPRKTLSETPNILSQRKVASSPLSKQNVSTSINKFIQQTPLKSPSVFTVFVGASPSSDNKPITDQRELENLFAESEPQTQFASKNATNLPKFMSAKRLNSGIVIKERVEGGLVVKDPSDVLKELNIHDVIDEWTEGIRRWLSLKVIVPLSKRIEVVDSEFKANNISEFNCLHCCTGLVSSTTSNSSISPTKHTAASSLFGVGNALAPKSSLFGSSQAQMPANQTNAKIGSFSELAQRYFHLPVVQERFKLENYLCVFDSSCRGYIVNRINDLAQGGCLSSFNWNSGGSYLNRPFNSDLFPTDAQLLMSLFCTFLDASMPGENSAMLGSHPFLSKYFLSVDSKPDPSKSIQIRHYSKLPPHYNLVVEGKTIWDVIRVTSNGYLGMLNLGGKSLNLLDTIYFSRPETIMKKTSVSFLVTNSTSTKTESKNSKLNTTRKGTGYIPIKAKNKIPQSNKKFKSFSISKQGPSVNNNKILREVGSDFLSILDSNAKKIQVWYRNIILKRKNLISSVIQQQTSNMKIGEVSNWKKLRQKFQPCTEVNSTLTNKDIVKKRREDSAKRVKDELLKEFLRHKSENSSMETLIELQEDQSENYLDFTDLCKEKLQPKHEEFSNDNVQQVYNWVLGKNESFSNVKHNLNSNLQQDINKREWKNSELADKDCIIQGSDGNAEIELTTLELNGSKNFFEEVCFDNLQESHTLQSHYSTTKIKKSDYDIPLGNALSGTSTINEWEDSLNSINENSYHNTVTRKPGGDSLPPGCKSIPSPRYSQINFTEIPCKEDKVAHVDSIIGEKLSDTESVQSIRAQNAKEINSDIRFKPEATKKLTTMQAEGKFCFESNKPVINEYTSNKSLKNLKVRSRTCTSDSTKTSSTISNKVSADSTWENRSKTNVNSCVKSRSRTDTKNESVSSYSTESKEENLEADSNYSQSLIQEEQTNERIERILGFLKNVEDDDQKKKSKLVIEKNATSINADAFTEPYKASSFGTAAVFDGVKAKIIGQQLELEEKTQTILAFKTEIKRLKEENKENANQYKKDLKSKTSLQKKEYETIIKRHLGFIDKLLLEKDDLGKKCENLTEEVKQIEKGFKEKCKSIEEQHLKEIKQQKELWQATEKVKRDKWISEKTKLIKDQTVKGLEPEIQRMLAHHKLQLRQLEEKLRDEFSKEKDLLIDQHQRQLANVRDRIVGERQKACEEEREFARQRYQKQLERDEMEFQQQKRKLLSEFNEQKQISSEIAKEERRTEESRLKNIVEGLRNELAELRLENDKNSENMRKRHQDELHALQEKLMAQKEDWQKQYMEKQEGEIRCREKTFKEKLLKERDSEIEMIIQRLESESGSGNSEVERRHRLELEKLRQEQSEELKELRDSHRQALDKILKTKNELKTCEERNMELEKEVLILQHSKQAKENTIKKQKDSLDRLQVDETALSDLIRTEFESELEKKEQLNKNLQQEIDNFKNQLDILQRKHQNEMIEITKQKESTFSIVEEQVKKTVAGKEEIINSLRLQIDEMLIKNNHLEKMIEKQRRELLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZE7</accession>
    <name>A0AAD5XZE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Centrosomal protein of 76 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CEP76</name>
        <name evidence="3" type="ORF">HK099_002185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000170">
        <property type="protein sequence ID" value="KAJ3222553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZE7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052299">
        <property type="entry name" value="CEP76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028926">
        <property type="entry name" value="CEP76-C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056290">
        <property type="entry name" value="CEPT76/DRC7_peptidase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46436">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 76 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46436:SF1">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 76 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15627">
        <property type="entry name" value="CEP76-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24656">
        <property type="entry name" value="CEPT76_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CEP76 C2" evidence="1">
        <location>
            <begin position="91"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="CEP76/DRC7 peptidase-like" evidence="2">
        <location>
            <begin position="368"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="686" mass="79707" checksum="D10CD5C5F6C26FFD" modified="2024-05-29" version="1">MNLKKLHQSLESEDFKKILEPIVNGARDYNQEEFKTLLKDSGIIEKISDELLNNSKSPQESFNTADESQKKEKLESDVNSTLQRLTRIGKLYFNLTLGSGRAFLAFKEVTEFVASSLSVHFKWMNNRFSSEKVLSTIEPAFNENWIIELESTDLLRLLEIDEPFHFVVIRSDLHGNNTLLGTRNVEWRQVLCYGSTSKVVDIKDIYNPQVTVGLLELKINFFPSQLKENLIRRDELDFQLKKEILNQKENDRLFFIYAKRWWNDFLLLKQGVFNNNFNKESRMIKIFTFEENSSVSIANNAEGDSNDDFGGRKVSVTFFLESIKCMYHKMPCFKILQGSFLQSPKHAARFVSLIPFERTLGIGDTNVDVWPNLHTFLSLGKGDVQEHAVLLCNLFLGFHLNAYVACGLGKKFSSVFLYFLKDKQNSAHLWVVTIDSNNVVTFWESLTGENFKLISKEKKKTKLDDDVETLNKKAASQRFKFFPYRTIGCCQHTDSIENCDFNLEDENKWKSFSREAIQSTKRYNNFYSQEFPFKSFPVNINDEINNEGFGNDFSIVKHDSHKKYFKLYKSPLKKSSHLHDFEIELAIKQKIVEYREDHGFSKKFSNTANLIEDKNLKYVLKQKIFNLENEKIFKKSFNYNVFECSFSELGSKVENEEIFGDALFFEGVKSLLNHGETFKLFPGGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZT7</accession>
    <name>A0AAD5XZT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1003 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000283">
        <property type="protein sequence ID" value="KAJ3220657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZT7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010406">
        <property type="entry name" value="DUF1003"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41386">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41386:SF1">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06210">
        <property type="entry name" value="DUF1003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="79920" checksum="0B34B88EAFFB1CFA" modified="2024-05-29" version="1">MEEIKIFSPSDPELEKVTSETPKERPLSTSFSKSLHVSGVSLQRIESTSSCQELKPFKLLPTAFPESDNKKPASPEPCYTQTLCPICSKVLPEPLHTQTIQLKKLKPRFLRQIRRNSEARTLSNLETRVCIKDLHSLLQHRIDELLEEDQIDFASLQENAMKFLQKHEAEEETWQDQFDKKRNFGQKAADTVAKNAGSWKFVIAVLAFIGVWASLNLLLYNSNPDHNKSWDEYPFILLNLMLSVVAALQGPVIMMSQNRQQEMDRVESDFISKMILRGEHQTRHVNAKMDYLITNQWRRLLEIQEIQVDLLQILQTQQQKLHHSKSTDNLGSLQDHLTSNMTIPNVASMMSNFFGGSHSRNFSRNDSIIKSPIPTTPWVLEIHPDDHTTMLFRHYFSKPESDDNLLFSHWAEEGDNFYGFIKNVKVEVENLKLGTHKSRGWLEVGGGVRRDFSAKVLKRITYEVDFGDQKANLDDIFSGDGTVKLRNDFEIDHMNTNGRIRIVDIYSKEKPLHAHTFQNGDLPTRYQPSFSKNFKRSERISDFWRTNLSKIGITYSPPHQASVISIGEGFRVTNIKVEFYRPEDNIFGEGIQNVSAFPSHCFKSKSFKTKLMLATGIEFAEPIKLLDDITNNNFFNDDWKEIANVEFESKVRSVDGDVLTVELDNNFSLTGPNIYVFLSLDARTVIHGFYEEIMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y050</accession>
    <name>A0AAD5Y050_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000102">
        <property type="protein sequence ID" value="KAJ3224164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y050"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004177">
        <property type="entry name" value="DDHD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF10">
        <property type="entry name" value="LD21067P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02862">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01127">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51043">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDHD" evidence="1">
        <location>
            <begin position="162"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3224164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="481" mass="55326" checksum="C8193272C60C76B3" modified="2024-05-29" version="1">MVKVTIYKTIKSQIISITIGGLAEFRIDQLKKSYREVLKEDFEGDDEIEIEFLPIEWQSNLKSSFDKINLCTLPTLGVLRRITNEMLQDGYYYFTKFHGQSIVDFVTQAYNTAWENFITRYPSFNGNIGIFAHSLGGVISYDIICNQEAKTPNSHHINYSKLNFRPKFLFSLGTPMSAVLVQRGFSIIDYQLPSWCHYMNIFHLYDPLGYRIEPLFNPAFAAIPPIPITRPSSKRSHFTHWNTLLEKILPGLPEILQLPGLPPNYFQNLAWPNLNHLTDMNNWPHIPSLPNLPEFMTSSFFRLGKRHREETSDVEEGHYFSDSETSIRRKNKRQRVEHNESVHTLTNNSILKDNTASTLSPHEVDSINVDNLESTSFKQSEIPNNSSLLPSIVSGFTSHVRNITEIPANIMRRMSSQVQSNSSTDIDSEVDLLVESAKEELDKNINSKAQVDNKTLETEDNYLEKLSRRYDYFVQETVVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0D4</accession>
    <name>A0AAD5Y0D4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA-dependent ATPase protein rad54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RAD54</name>
        <name evidence="9" type="ORF">HK099_003261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000216">
        <property type="protein sequence ID" value="KAJ3221670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0D4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000010">
        <property type="entry name" value="DNA repair and recombination protein RAD54-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000332">
        <property type="entry name" value="DNA repair and recombination protein RAD54-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="204"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="559"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3221670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="806" mass="91163" checksum="B85E797AF97B226B" modified="2024-05-29" version="1">MKRSKTPSLLLLNNSKSNESISRKRPSPRKASLNQQKKVKVEFDENDNPNDYKSNNSDQDEDYEDEDSLKPLKLSFNSKIPLTNRKATLGISVVSFKNTFQVPNFLKGDRPVGVRNGGSQLGVTKRNSVSKFSLYDPEAEGALILYVPKETFGADQLINLKSVCNPLIQKVDIEVHVIVDPMLSKVLRPHQIEGVKFLYDCVTGKKKEGCFGCIMADEMGLGKTLQCITLLWTLLKQSPNPGKPTIEKCIIACPSSLVKNWANELKKWLGADRIHPYACDNKGSKEQTTRDIEIFSNAKGRGVCQPVLIISYETLRAYTEILKKTEIGLLLCDEGHRLKNAENQTYAALNSLNAKRRVILSGTPIQNDLLEYFSLLSFAIPDVLGTGGEFRRKFENPILRGRDSMATDKEKEISEQKLEELLAIANQFIIRRTAALLTKYCIILGMPVKYEHMVFCKLTPLQTQIYQNFTKSKEIRKLLNGDGKLQPLQAITNLKKLCNHPSLLIKDSGEITYTSSTRGSNKKLSKVTPQGDGFVDMSIFPEDFDFSGFQSHYSGKMMLLESMLTKMRKESKDKIVLISNYTQTLDLFQKMCRIRRWQCVRLDGSLTIKKRMQLVDQFNEPNSEDFVFLLSSKAGGCGLNLVSIGANRLVLFDPDWNPANDNQALARIWRDGQKKTCFIYRFIATGTIEEKIFQRQAHKQSLSSCVVDEAENVERHFSIDSLRQLFELNSETLCDTHDTFKCKRCVKGKQVKGPPDGKGYSSKSKCCKVEVPEARALIRQHGIISVNWTVSSLKFMTLFLRNVERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0H9</accession>
    <name>A0AAD5Y0H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000278">
        <property type="protein sequence ID" value="KAJ3220729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0H9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="353"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="571"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="807"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="902" mass="104775" checksum="21F20D6A32FCC4E9" modified="2024-05-29" version="1">MNQYQKLKKSKSIVTLKNAINNTWEKRTSISVEIAPLIENLKGSRRISSGTCKRKTTIDGKDCYIITPVATESPEIPPLFQENIPLALINEIPEVLFRSHILELNKLLIEAHCTRAKYYSVLKICCLILLTLLVFIMFCLMLSSRLNLAFFFFLIILSVVICWPLFTKYWFTSFLGNVQKQIQNSVVEWNYRAPQNVSFRILTAGNFYRHGEHFGVDELSADLTTNAQKYESFILEFLKANKKIKPRGVSLQAIRRAYMNEAQANDEIKLLVKEGKVIDHDYNKFSIASPNNRFSRRFNQTPTIDYSKEVPDHQPYCTSSGRKSCTPLKFGRIVAPTTSRKYQRKLSETPSSIGNLSQEINQLRRERNISNLRIRDLESTENELREKIEELKRNFDEKHRECRELLKEIQDLKKERKELRDNIFVKENELKRLLQAANASTITQESSTICINESVIYDFDESAVMLNHSNEDTEITEIQDAIQEHFGDSDGESSVGNICATNAADSPMNINDLVNETTELHNVLNVEPVNGFINEVDSNNSEISLLKERILKLKNDLSGKEALITDRANQIQEMESAAEKQTTYMEQLQRNSDEKISKLIEEMELIKIQMNMEKKMYLDQIEELNQKFIASEDEKFKTERVLREKSATLSNYQQELASALDKFEKLDEKFKKLTFENNMLQQKLNAKSVELENEISKFNFQLSEMETRLGIEFSEKTADYLKTTEEEKVNLINEHTQLTENLQKEVMDLRTKLAEELSLYNEKVKTIEGSKEILKTKYEKELHLCKSEYESLNLHFEETLTLKSQVIAKLTEEKAGLEQNKLHLLQEIQSKYENLIKEKEEAEIKIKEVEMRVKATLNNQFTEIKLKFENTLISINEEFASDYSSFGCNQMLNSEYFLLHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0S1</accession>
    <name>A0AAD5Y0S1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trafficking protein particle complex 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TRAPPC8</name>
        <name evidence="4" type="ORF">HK099_003703</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000245">
        <property type="protein sequence ID" value="KAJ3221198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058541">
        <property type="entry name" value="Ig_TPPC8_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058538">
        <property type="entry name" value="Ig_TPPC8_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057651">
        <property type="entry name" value="Ig_TPPC8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024420">
        <property type="entry name" value="TRAPP_III_complex_Trs85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975">
        <property type="entry name" value="TRANSPORT PROTEIN TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24545">
        <property type="entry name" value="Ig_TPPC8_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24544">
        <property type="entry name" value="Ig_TPPC8_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24542">
        <property type="entry name" value="Ig_TPPC8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12739">
        <property type="entry name" value="TRAPPC-Trs85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPPC8 first Ig-like" evidence="3">
        <location>
            <begin position="603"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="domain" description="TPPC8 second Ig-like" evidence="2">
        <location>
            <begin position="792"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="domain" description="TPPC8 C-terminal Ig-like" evidence="1">
        <location>
            <begin position="1170"/>
            <end position="1262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3221198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1297" mass="148120" checksum="A6B86E1201A23683" modified="2024-05-29" version="1">MAYIQKCLSPLAAIIGSEDTRSLTSKNNLPDLAALFSPFGDPITSNVTLRDSKGQASVVDNFTLRFKGLNELDIFDYQQLNSVLTEPLPPLLHGNLKVDLNLLKQSGVGIEYEDFERYTPWYTQYRDYFSLFDGPSEHETFNHPIACIFVVTTENPDPVSTFSLLSSQASLPKIFEKGFMDKNFLKHFLLIHEEKSQSQQNPEQTLIALKKAFGLNCSLLKLSGKENLTELRDKHYYDYWENHIKLQEGFSKAVVKSADENLISVSEKDEQILHGLHFSKVDINNIETFVIASRKGMAGRLFSAFSRSSKSSVQPKNSLIDASGKFMYLSDSSEVLQRKLADYSFMLRDYVFAYSIYDSARKLYQNNEQASRYFAGSQEMLGFCVLMTEGVSKVTIESNFDLAVDTYKFSKDFLYETRCTALFFEMLKHKKFHRDAPTLLNKMTGESAFCFLTESPIMARKYAFFLVLAANRYTKCLQRAHAFRCYSDALNVYETQGWTLVEDHINFSLSRQSIHMGDLVSGVNFLSKLMRSSRQSPKIQAEYLKDFYFIYGQLKSIGKKEDMEKLKPLNIPIFIDKSTIISLSRNALNSQSQNDERTKVNDEHWELLESDLVEYGYNKNQAIKKNSSNFSKIVSVKQAVNILTCAVGESVFVHLEIENPLQVSITLSNISVRCNFGSIPREDEDYNDGDRSNLILVERSGFTVENIPDFILGPNERAKLQVAIIPKQEGTIYILGVVYLVGGLIPCFKSLKSAKKNLNKEEEFVTPKLNVTLPMPVLDIEILNFPEKIFSGEIIKLFLNIKNNGNRGLVNLKLKLSHPSFFYFGSLLDVDQEEYVYLENGKNSEKFLLNNNLNDFSLLSIKLPTKDLKSASEFEDGVLMPEQSCLVPIFLRGDRMGKHTFRFLFGYQAEENETPANFRTFKFTQNLNVQPSLRINAFTRPSQRNLDEFTLGIEIENLQNFVVLIKQLSAVSSKWQIKTVNGLFSRIDNFKFEKETSPEHLVSKVIESIMYTEENITIYPPPLNFHISSLSMDKVFTCSENPFKEFSCRSRTQWRMTSLSQNYNGLSPEKLRKLFTLYYSDDVDLTLFWEMPATSSKEKKRLGHQYIMGINLSLQSPLTEIQSKFLGGKNMEGIPESRALFEQTVREKKTLINTLLKSKSKEVSPLRIVFNVNENYFHDFIKNGDCVLSFPVVLNNSSSVRSVKFTLELLSAENGSNLKVMIWSGKNFINGILKPEEEGKYNVFATFASPGIYELNRWKLSVHMLDDNGNEDKGNSGFIQTPNLNQSITVHNRIDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1Q7</accession>
    <name>A0AAD5Y1Q7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_001740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000152">
        <property type="protein sequence ID" value="KAJ3222934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1Q7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="387" mass="44497" checksum="EBED01A78E952825" modified="2024-05-29" version="1">MSHPNYKNVEVNQLTIEQQRQLLLSISPQQHPQLPITTTLNPSAAFQQHFNAGQYSPVNINQLQASFNQISQPTTSLLNLQPPLLNFNQQSPVVNNLNSNYLMPQINLMSQQQPQYPQQLQQQLLMQQQNPNIRNNQNYQQQVLPNQNLPKPSIPVVPNYSMGNSPQQRHSPHTMNSTYHRGAGLPGSQANLNMQQAYYMQQQQNRNISYQAGNQVRTNSTGSRTPISGGAPPRLSGTPISKPVGPFRTAEEIKHHEEIKLKIKNSLIADQQRTIQQKQHLSAAFENIEDAKMKLLSFHIFNYPHQNPQRKTKRVETDDGKVTEELIDEFEGIKLKTKSLYERFFNLNMVNFEELNMKRLNEKIFKEGEALFEQERLKEKAALNFQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1T9</accession>
    <name>A0AAD5Y1T9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Riboflavin synthase</fullName>
            <ecNumber evidence="3">2.5.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RIB5</name>
        <name evidence="10" type="ORF">HK099_000079</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.9" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000010">
        <property type="protein sequence ID" value="KAJ3227825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1T9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000004">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000006">
        <property type="entry name" value="Riboflavin synthase, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006767">
        <property type="entry name" value="PRK09289.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098:SF0">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="RIBOFLAVIN SYNTHASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="8">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="9">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="8">
        <location>
            <begin position="106"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="9">
        <location>
            <begin position="106"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="265" mass="28826" checksum="E25B3FCA87980F08" modified="2024-05-29" version="1">MFTGIVEQIGKVFSITVSDSTESGGGGFSLVIENANLVLDDAKIGDSIAVNGVCLTITEITDNKTKVKFGIAPETLRKTNLGELKVGSVVNLERAMSVGQRFSGHFVQGHVDTTVKISKITQDPPNSVIFEFTVSPSSELSGGIDFLSYIIPKGYICLDGTSLTVVSVDQQKRTFTVMLIKYTQDNVIMMTKKVGDSVNIEGDQLAKYVEKVVMGMLFGGKFGSEGRSEWSEGDQKVIQSRTENQLELLISKIVDEKLSQHSKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y205</accession>
    <name>A0AAD5Y205_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000085">
        <property type="protein sequence ID" value="KAJ3224675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y205"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3224675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="100" mass="11239" checksum="0A13D54E7094582D" modified="2024-05-29" version="1">MFIKTRVTKPATQAAASTWQTADDKLLGKIIESVSKHDLRLIDEDADAWTNFSILVKSHRNQYLYNICFHVPCDLSTTEFVHGLAGCENICLIFCSCNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2T8</accession>
    <name>A0AAD5Y2T8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial resolvase Ydc2 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_007206</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000068">
        <property type="protein sequence ID" value="KAJ3225194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2T8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039197">
        <property type="entry name" value="Mrs1/Cce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015242">
        <property type="entry name" value="Ydc2_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28072:SF1">
        <property type="entry name" value="CRUCIFORM CUTTING ENDONUCLEASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09159">
        <property type="entry name" value="Ydc2-catalyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial resolvase Ydc2 catalytic" evidence="2">
        <location>
            <begin position="338"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="564" mass="63893" checksum="1993BEC884536BAB" modified="2024-05-29" version="1">MMDADENHLTKDESILNPSNIFLLSQKLDSPHKNNLDISISRLNILNASKDNLDKRSYQNRFTLSEFTNSKLNLSQQIRFIHSNVSQPITFTQVTKKKKIKWTEEEFNYLVKSVQSSKPLYKLFLERYPYRNADSCRKKILHSKLSSESSLFFSNAVAPIRARNDTADVKVGELQGSRNFNDSRNLDATAITGYSTTANIDSKCEKLDLEKKKKSKNSKNLNKKLTKNEIQNNNKKDGLCNLNGEKKKICDEPRVSRKQNNITEGTKNLIDIKTKKTIKIHPKDDSILKNQLDSTKGLESILRSCGVTSGTPKTKAAMREKLLLHLSEIKNLKNPKIVVAIDVGLVNLAYIKISLESEIPKILEWKILDVNFPATYDSVRYARVVQNLATCNFKDADVVLVEKQSPTSTSWGGVTPLVIQRCVVVEALLLGVLINQNNVKYVKSCSPSFISKYFNLGSFKRTEKKKKTCNLISKILGSGIAKNGIMNDILTLDLKKDCLIYPDIVDVSNTTFFNKSAVEINTSILDNYYAEKKKDDLADCFLIAIGFLEWYKNSLKLLETMQCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y2U3</accession>
    <name>A0AAD5Y2U3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_007148</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000067">
        <property type="protein sequence ID" value="KAJ3225230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y2U3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045041">
        <property type="term" value="P:protein import into mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052604">
        <property type="entry name" value="Mito_Tim_assembly_helper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082:SF2">
        <property type="entry name" value="CHY-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28082">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="117" mass="13752" checksum="25E57A64BB494009" modified="2024-05-29" version="1">MCKHIVNAQVSVRAPCKKWFDCPECHEELAKDHPLQKTHEMVFACKKCKKVFRKDMAVYEDSDEYCPNCDNHYVIEAKERKPELQIGVEGDDPRIMRDYRAKQKYLNPDEVMADIMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y318</accession>
    <name>A0AAD5Y318_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000030">
        <property type="protein sequence ID" value="KAJ3226720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y318"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01301">
        <property type="entry name" value="RGSPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="132"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="806"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="857" mass="96736" checksum="275421D617219E70" modified="2024-05-29" version="1">MSGEELLVVANTNLELQELVSQIEAEYLIRLKNLTSNEEQNCKIGNLFNTKLELLDLKERVGSCLTFNDQLIVEFKKEFSVVSQFLGEQILQPRYSEEATKKHNSENNSNLNDFNENEEKLIKILNSFSLCYFALFCIKDYTIEHLLFWYLSEMFAKDITEESNLWKVAQYIYLLFIKQGCPLKINLSSEVEKIIQSKLESSNDSNWSENLFTNAQTEIFQFLKENTFTKFEKNNKIRQAMEADLLKDSHTVEKLTWDIAKIDDTVKKLVIHWHSTKKNDTKDLEFKEMILKDTVKLYFGDIYANDYFDVNKRVSFGTKQVMASKEKRIKKFFGENMIPQAANNVNGNPLVLNGNQMTQEINDNFLDIEEKVESFNKTDLPSNSSIDIKKKKLKKITDIFGEHIPSTELVVQKLINEPEADSENSNSSLQTEGTGKTKEKSNSKLKKNLMNGGVDSADEKIIEAILTNLHKENVGSSCNNYQKPNISPVEDISPLGRNKPVQHKKLSQLFGEQTTSAILILEQQLKETGKANHSQPVNKKTEELVEGTSKEATAVVEIEQSLKNSSPEGPCQLESNREVEKHSNNSIHEIRKDVEVKFDANQNSKLIMESEGLYNDLIKNISVVVNSTNTQNSNGITSTAKISNFSCNGHVTNSKTVEMDDTTKPKRISLTNLETLLEKLNSSKMNESKRKENVTTVLQELSSAVVETNTGCLPKETSEKIKNMEAMLATLSTNIKGVADMSSVNLTVHNTTQPGITKPSLHESLVKATSSAVTNEGKNNSKNNLTIFNNSLLELDLELERVKAISVPSKSKEGSQSDNEKILSSNRINEKLQAFERFEQNASRKIFASGTTTNNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3D1</accession>
    <name>A0AAD5Y3D1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NAD-dependent protein deacetylase sirtuin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SIRT2</name>
        <name evidence="10" type="ORF">HK099_002167</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000017">
        <property type="protein sequence ID" value="KAJ3227416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3D1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="518"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="684"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="684"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="714"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3227416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="900" mass="101870" checksum="713339B4AAE00F15" modified="2024-05-29" version="1">MIKNIHILGSGSIGFIIGKALSYSKISSTYLIKDSKPKFSSFQINGSTFETNSEYINESNDAISHLFISTKAYDTVPAIRSVFHRLSLNSVIILVSNSSLFLFNVRVPKVQNGLLGVQDELQKSFTELPKLVFSSTTLGGYKSKDLVVNQTGCSGLSYFNIKNADCRTRELLIGLKCLNPVLFDGNSILEDLKFRNLLIQKLHINSCINPLTTISNCLNGELLNNERNAKLIIELTKENEKIFKLYFAGKENGLNEVQNKELEDIFTFKNLSNAVYSTLNVTKNNKSSMLQDFLKMKKTEIDYLNLYIVKLGIRVGIDAKNNKLVYEMFREKEGQSCHGVYTNCRKVARARDNDCNSTSSDNHRVLLINNLFLNLIVYLQYYPCYQVLDPGLCRMQADGECAWSVNSTFSDCLAKYDSEEQLNSTDVIYINTTEEFSETPATRTSSVMNSEGTGLSQLMGVLDFLSRYLIDLQDNSLLDMGDDISFGLNHPNMERGMLSTEQQCLTALEEKLKYPSLNVIKDNSIESFADYVKANKCSKILVLTGAGISTSAGIPDFRSKGSGLYDNLLKYNLPYPEAIFDLKYFKRNPEPFFILAKELFPEQKNLLLRNYTQNIDTLERYAGISSNLIIEAHGSFKGATCVGGISEDGLEKLKSVERERSKHSKFEVDVVQGKTEKFDPRIEKEMPKNKSDEVAFNESEPLDQQKQNDRNTEEIAESSSSEDEINIEDLTNSINKFNLENGEKKDQKLKQEAIFLSGCGKKFENSYIEKKIFNNEIPRCDNCFGLVKPDITFFGEPLPDIFHKSIENDFDNCDLLIVMGTSLQGCLKFADLMGWKEELLDLMMDHLKFLALKKKSEILKEPILETSAMTAKEEKISEVKKEKEDKLVNDLKLSLKLEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3W7</accession>
    <name>A0AAD5Y3W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001122</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3W7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3227615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="22431" checksum="48B6BF4633B89B67" modified="2024-05-29" version="1">MNEGNNIYSAMFFPSEVFDLIICYSDDLIALKYFMRELREFTVIPWNMTFLKTIDNQISNRNIRYINRLRRSEIYVELTNMVLKLMDIDLLNDAYYDVLVYYDRNADKLDPGQSYQELDVWHDYEWIYNGEGIHRDFTKTCYPFEYKDVTLYSQSILFNDILPFTFGKDSHMIGKDAYNMFEDVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSU8</accession>
    <name>A0AAD5TSU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">F-actin-capping protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003107</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the F-actin-capping protein alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002089">
        <property type="protein sequence ID" value="KAJ3199543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSU8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030863">
        <property type="term" value="C:cortical cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.210:FF:000003">
        <property type="entry name" value="F-actin-capping protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.60">
        <property type="entry name" value="F-actin capping protein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002189">
        <property type="entry name" value="CapZ_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042489">
        <property type="entry name" value="CapZ_alpha_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017865">
        <property type="entry name" value="F-actin_cap_asu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01267">
        <property type="entry name" value="F-actin_cap_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00191">
        <property type="entry name" value="FACTINCAPA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00748">
        <property type="entry name" value="F_ACTIN_CAPPING_A_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0117">Actin capping</keyword>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3199543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="272" mass="31149" checksum="D82A1EADDD2E6A15" modified="2024-05-29" version="1">MSKEEISNEILLSSPPGEINDVFNDLRVLINDDTLLQNLKPTFANYNKSNLVFVNLPESNPVLITPFNELDNGSYFDPRTNQSFDLDHMTHAISNIESITKSEKFESIRKVLDDSILEYTNEHFPEGVSGVFETVKNGGEIIVCISDSKFNPNNYWNAKWQSLYTLSIDTKKLVGEAKVLVHYYEDGNVQLNVNRTLSINLDYDLDQPETVSTSTLKEILKFENSFQNTLNESYSKLTGNAFKNLRRPLPIFSTKIDWNTISSRKFKNKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTZ3</accession>
    <name>A0AAD5TTZ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">TBP-associated factor 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HK099_001388</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001387">
        <property type="protein sequence ID" value="KAJ3203726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTZ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007900">
        <property type="entry name" value="TAF4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05236">
        <property type="entry name" value="TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID component TAF4 C-terminal" evidence="10">
        <location>
            <begin position="31"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="69"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="141"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3203726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="242" mass="26726" checksum="B7374B3CA4D460C1" modified="2024-05-29" version="1" fragment="single">MVKASKHRKGINYQKFIKEEEKSLATSILLDNSKKQKVLVTLTSQPKKRMAELEKMEKDEERRLRVANGFGGIQGEEDFNGSTAGGFPDMSNVDDEEDGGKKKKKKGKKADQPEHIKTANANSRALTAFGGELKSWMVPKGQFDDPTLIAPKKKNKNKDNSPKSGGSSPSSSLIGSGAVGGHLQQQQLQQLLQQNKSISELNTPLYASNGEQISKIMLDRDLKRISLVDALFTLERDDNLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUF6</accession>
    <name>A0AAD5TUF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001244">
        <property type="protein sequence ID" value="KAJ3204994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUF6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3204994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="768" mass="89087" checksum="A60299F108BDE63F" modified="2024-05-29" version="1">MKAFIPTESIEKIELGREVKKQDSKFYYTIKVYPTAPKESYLIQRSFTDVLNFDGIISNYVKKKKEVTKGEAVFLRDFTLPTLPKQKFILTKIVAQNRLIKINHYLNFILKNLFFKLIFFDKNFGITTYPPLDEEDFSFKNIFFEFFGIWKIDLIQLNSNLNFEPFDIEVEKIKLKKNKKSQDQLFFFDKEEEEEDEEEEENFEEKNYFTLNKSQVFNNSNLSYSSASDGFFNEKYEETSQFYSYTSNKSSFLPLEKAATFSNSQSSYDQEFSASVTKINFIAVASSTFDDTVIDDNGRVFKDKVFALEESSYRSNNVFSKRDSLHQIQSVVSDDFINSHSLTSNLSTYKPPISVSSFADFDVLKLGPSTSPESENTALQPPLRKSSLSNTYFPSYSTPEVIAKPQLEELPVVSPLPLLVKKNDFSESKQCFQFKNEEELKFSSLNFGSLNNSNNVENNSINEFDFKKKNWNTLPKPLKVVENYGFQYNNLSLPREKTTPLIVIPEQYRFKFNNGVLSREFENTPIQQSIPNHHAQVPQFLPTLLTSRAEEDNFEKKENFLKKEEEFIQPELLPIPVENSLSLDSNIENKLTLVSESSSESNLNLKTDTNTTSSNDESKKENSFENNFSDEVVTISRPRLMEREKERNLTGVLRKSALFRSHSLTSTTIQEINQHYLDINVLMDIDSLISIKISRNISFKDLKDAILLKFVALLCIKEEEKIEEIRSRLETLSYRSENQWILIADEDGWVTCKDDVFKFTLLLIVRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUJ8</accession>
    <name>A0AAD5TUJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001213">
        <property type="protein sequence ID" value="KAJ3205337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUJ8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042289011" evidence="2">
        <location>
            <begin position="21"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3205337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="282" mass="32783" checksum="60B07B872DF2B75B" modified="2024-05-29" version="1">MKLILLTALLLALVAARSYGHKDDYHKGYHKGYHKGYGHHKHNHYGKYHKQHYGYKKKHYKEYANPEDLEFEELNEEDVQALTPQFADPPKTNTTVKNTTPTKNATETGAAERDDDEDGEDSEDNDKDLAQGGDEEFDEDEGDDDAEGQPEDETEDPEDQELGDVSPEEGDADAGSEPEDDEQEADNAASLNSQESYGYQKKHYGYKKKHYGYKKKHYGYKHKYHKKSYKSYANPEELQSQESYGYKKHYGYKKHYGHKHRKHYGYQKKYHKKSYADADEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUS5</accession>
    <name>A0AAD5TUS5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001259">
        <property type="protein sequence ID" value="KAJ3204851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUS5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="146" mass="16889" checksum="4EF23E4598E86EC5" modified="2024-05-29" version="1">MNGEKQIPPAMYPISKPYGGFTTLLHRFGLYEREMLKPNLNVKEHQVQHNYSNQRVDLSPRQQIKLELARLSSQIQKFKSEYKNENFNPTQRITGNQAPVAPSKKIAKEELEKWIFMVSLLEKIQQIESEKEKIATQNLSSSSATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVF3</accession>
    <name>A0AAD5TVF3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Xylose isomerase</fullName>
            <ecNumber evidence="2 8">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the xylose isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="2 8"/>
    <dbReference type="EMBL" id="JADGJW010001727">
        <property type="protein sequence ID" value="KAJ3201439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVF3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48408">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48408:SF1">
        <property type="entry name" value="XYLOSE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00688">
        <property type="entry name" value="XYLOSISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0859">Xylose metabolism</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3201439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="263" mass="29541" checksum="57341A764BD99E5B" modified="2024-05-29" version="1">MEVTKKLNGASYVFWGGREGYQSILNTDLKTELDNFASFLKMAVAHKKQIGADFQLLIEPKPKEPTKHQYDYDAQTVMGFLLKYDLDKEFNLNIEPNHTTLAGHSYEHDLAITAAFGKLGSIDCNTGDESLGWDTDEKKATFVMKLVIKMGGLGQGGLNFDCKVRRESTDLEDLFIAHVGAMDVFAKGLRNAAVSINGKLSKMLTERYESWESKEGKEVRSGKSSFEQLEKFIKASPQIPVLSGKQELFDRVFNDEIHDALRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVJ3</accession>
    <name>A0AAD5TVJ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">adenosine deaminase</fullName>
            <ecNumber evidence="3">3.5.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_008692</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="3"/>
    <dbReference type="EMBL" id="JADGJW010000989">
        <property type="protein sequence ID" value="KAJ3208543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVJ3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043103">
        <property type="term" value="P:hypoxanthine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060169">
        <property type="term" value="P:negative regulation of adenosine receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF43">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="8">
        <location>
            <begin position="36"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3208543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="356" mass="40384" checksum="F7DA70FE27E25F0E" modified="2024-05-29" version="1" fragment="single">MTAYSIQQSSLTTHPTTSQQPHQTNPLTRTEIKSLPKVEIHRHLEGSIRLSTIIDLCKQLDIHVPNSDNHLTKSLEPYIDMFCITDKVDNLTAFIEKMWHAQSLLKTPEILERVAYEVCEDAFQNGVKLLEIRYSPSWITISHFIDHSELTIESIHTAVVKGANKAQQDFDIVVGLIGIMDRSLDPGTARECLNFFLKNKKEFIGIDLANDEKYSCLPFKELYEEAKSFDVGLTCHAGESTTAQNVSETIINLNVTRIGHGFRSIHDEKVLDLLKKKKILLEICPISNVRTGSVESMKSHPVRKLLDAGIKICINTDDPGMFNSNILDEYEELVKHHNFTKEEFFQCNLNALEASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWL1</accession>
    <name>A0AAD5TWL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Clp ATPase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_007267</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000692">
        <property type="protein sequence ID" value="KAJ3213627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWL1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000002">
        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="3">
        <location>
            <begin position="203"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="371" mass="41072" checksum="EF41E66533C94F3A" modified="2024-05-29" version="1">MLTKVTGFGSNLSIGTKSINDATPLTQAGYVGEDVEVVISRLLQSAEYDVKKAEKGIIFIDEIDKLAKRKEGGGNQRDVSGEGVQQALLRMLEGTTVNVTLKNPPPGSKRNAGEIFSVDTSNILFIFSGAFCGLEKIIEDRIGASKGSIGFNASLKTPKSEGSDNPTRSSDILKKVEPEDLVKFGFIPEFIGRVPIIAAVTNLQESELERILLEPKNALIKQYEKLFKQSGLNLTFHKEAVTKIANLASKKNTGARGLRRILEQTLVPALYEYPGTNVRNLVVLKETVEKKLPLATFTDMQSLEFKDSLKNGTFYKCDVFTEEFDDEYEEIEEEVYFQDPSVVEECEVKINQTSKEHLINPETAPTPQPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWR6</accession>
    <name>A0AAD5TWR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001420">
        <property type="protein sequence ID" value="KAJ3203502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TWR6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3203502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="552" mass="65116" checksum="F73EB58531B7FD95" modified="2024-05-29" version="1" fragment="single">MEVESPRVPPLHHQLYNQHNTHSLDTFHYSNPISQQQLNSSTPYIFDTTSTNQLFKSNKTENLDSQLPYNLYRPENLLNFSSSLEQNNFKKKNQQTSFNTLDQQQFNDLKQKHSNFNTLNQQQVFENVQKQINLNKNVEKPPFKLNQLIPQQHPLIDSSLIYSNNNSNQSLNPFEKIPHNQVVSQSSELLSPFPQNQQIHNYLHDIQNPVNQPINSSEIITIPNPTNWYSNTNILYQPTPICEIGVNYIKFLTYLNGIENLANISLPEEWKNKILKVGKKGGRIDEKTLTEFYHNLFDGRLNLETVSNNYQLLRKNSFKDTLLKHEIMLMNVINKFKNDIKFKLLDEEKEKSNFKFINVKNNLDNFNPLKHLNMEILNVLKESLAYNDNLNQVNIIEPKDLMKFEITDLNYKERTLCGIMFNVKRSDALTTLMRKSLIKEMIDDLFKKLNSIMDQVLKNAIFKEFKHFNKKFNKDDLIDDDFKFDKELTEWFINYLNDDLDTALFSLNNNFNPKRKNNNFTNFEVRSNLFGLFDNKTDNCFIWLKIGVDINW</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXG5</accession>
    <name>A0AAD5TXG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="5">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DHR2</name>
        <name evidence="8" type="ORF">HK099_006983</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000640">
        <property type="protein sequence ID" value="KAJ3214220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF91">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="732"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="940"/>
            <end position="1103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3214220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1449" mass="167923" checksum="D9891B8EDB7A05DF" modified="2024-05-29" version="1">MKRKKLNVEYKRDFNKKVKLRSAKTEKFYYTSTEKNTSIIIFLSVDNFTRGHIMRNSDFSKKIWEASILCDISSNIYYKFLVDGIEKIDKTQKYIEVIPGEIFNIKNVKEKTVKSEVLSDNVIIIDESDDDVSILSQKKFNISSVAQEVGAAANDLSLSAFLKETAKDHLIKEGDLTCRRKSELDEIAVCILKKSVNLRDLKRMWRNILNSQFSDICSWSKPATNFKEFDNDFNAADHQSLRVRIPVASSLLFGTAEPPLTDGKKLSYNQCFVNIMRDGENVVILVNVPEFSHISDVIIFPTQGPVPHAYQASGGDLDGDKFLVIWDQNFIPKTSVKSFDYNTTVMRNTIYNAFKRRNIPVIPTKPCETDLDFFISSKPFERVGKIDSLIRKYQLSLQAESEAESDETLMLLNTIFNLGVDDEEGIPEIDTLLSVLEREINLKSSSKLSTFGELENWFLKELKSCKRIFEERFELFYLTDVFWDTFKQSVVKLRLKFKEKTNILDNLPFKREFESEVKSLHIIEMEKIQNFRKNVEYDFDISSCNFNNLHQRLFYEIKLKFGAQRLFNIQQVFQEIIFEKIFVKIKSFGVCNGINNCNVKETFTTDRMVQLEKNFKSFILAYKNDAVKGKMFSKNEKKLDCISWKSTDITSYSSSSTISNISQLEESERYIECLLKREANFLKFLNNILHCDEKRLAHSSIHEVGRVVDVEVELIKRASTTLAIYDYGRDIVESIKKFNLTILISDTGSGKSHCIPQILLNEKIITSENTSMKPIIVAQPMRNAAASLANYSKEFRNTKLGEEVGYNLGGERTVANKLVTQLIYVTHGILLGQCTSNSSFSQYSVIFVDECHELSSQLFLLLSYLKRALVFNKELRVVLMSASLKERSLVDFFGECNVIKCRNKRGYPVETVFMDRPFNTNIVDACVDVASNLHKTKTSKLPSTMYEDILVFLPTSRDIETACSQMRKLKLENLAILPFYSSLPEEIKKSVISNSVNRNYRRVIFATNIAETSITFSNLGYIVDSGLQFQVKECLVTGIKNRNVVNISQSSHLQRKGRVGRTHAGTMFCLYSKDDLDNFKKEYDPEFENLEITILRMVKCNIDFYNFQWYKTPTEKEISHTVEQLLDLDMLEKRNDIFSCTLFGEILLETACLGFEAKHLLMLIYSIDLNCFDECLTILSFLIYQKPFKLRDANDQVFNCVHEIDRNLIVDLTYDEEEEEILLIPNPFVKYSSSMLLCISHDYHEYLTNINSEQKKKFCTDNNLCYNAMKYISKIKNKCKKVLKTIDFEQKVKKILVLNEEKKQLEFNLNNLKFKPVNAASPMLERLRYCFFTGFYKNLCVFNYDESHSRNDLVVTLMFKRKNFKYAVIAKSEENFFNFKKPFHDYVEEESTDYITGRYVFYCFTNITCISNKLIVSGLEHIPSIFLSAGTYGLPERFRKMFEELFLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXU9</accession>
    <name>A0AAD5TXU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002126</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001687">
        <property type="protein sequence ID" value="KAJ3201682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXU9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19953">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3201682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="502" mass="57930" checksum="4A0A4C1938FEAF43" modified="2024-05-29" version="1" fragment="single">MVEKRTGLELNFGKLKTTELASKLKSINQTLKKTEQPTEELKILCLNLVEPKLLTHKIYVPDHPFDEIQLQDVFTVFIHQLKNLHQPENPFFTYYFQLAESLTKVRSICLMGSLEQEVHDELMIEFFQNSFNNINKNTPINVYLLISELLVNLIQEAPSIPSPVCRLIINHFEKKKKIENITAHQMAIDICKSTTMKLQRFVCQHFSELLNQASNTSIPGSPNSSSDEAPSSKQEAAKALLSVHKLILQIHNNCPDLLINVIPQLEMELECEVETRSLAVQILGEMFLDSRMEQTPGMKSFYETWPGVWKSWCDRRNDSSVLVRTLWVELCANIFKFKPELIKALTPCLHEKLMDLEEKVRIASINVFKNLTITDIINIPKSLLLDVSERCRDKKINVRNEAATVLAKIYNKCFKLIKSGENLNASDKFGWIPSHILNLQYVDDKELIALIERLFNEEILPPNLNDDERTDRTLIFLDSLFLSENVDRNRKAFLAYLDRQDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TXV5</accession>
    <name>A0AAD5TXV5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sorting nexin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_008519</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000943">
        <property type="protein sequence ID" value="KAJ3209384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TXV5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF47">
        <property type="entry name" value="MEIOTICALLY UP-REGULATED GENE 122 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sorting nexin C-terminal" evidence="2">
        <location>
            <begin position="253"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3209384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="358" mass="39513" checksum="4F468866EC3E92CB" modified="2024-05-29" version="1" fragment="single">MVSSDVKQAKIRQKLVADLQIWLGVLLSDEAICENEYFEDFMRPSSLVKSDVVSTSNSSIVSKTFGGIAKLGSVMKKVATDSGKGVISMGVGAVGMVTGESAKPAENGVVPPPQVASTDFTKMMDNLEVPARNSSIQDVVPAFPGNGTFNSTMPDGERRSFTFRSSEDTETSSINNNSVMTPERVSSPQGGLRRRSSDKSTSPERKKVAKPKRVDSLNDKYIENLSKAELEIILECAFGVIEEAFNLSDPEQWIRQKGLHMVKSILRRTYGPAISNFIKKMLIEQKSPENISDHIRNLKNKFWDKDDNFITEVKPPRTETQKEDDKILAKKIFVEGKLFNLDGLVLMVGKGNTTKGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TY20</accession>
    <name>A0AAD5TY20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_006319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000538">
        <property type="protein sequence ID" value="KAJ3215504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TY20"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3215504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="154" mass="17738" checksum="8B50B6ED43F456B3" modified="2024-05-29" version="1">MDIKIVELNSIYALVIPKSNDDIAKKNKKGCLNDLKEDAFVELGKIVPAEKVKYKTGASLEPTATLYEFGFGFDDETFIQSLPKIPEGIFKRIYERGIWVVLSLKDHHDMQEGWKFIMDWTIKNGYAPNFERGDPYELYKSGEEVEIRMPIKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYF4</accession>
    <name>A0AAD5TYF4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CYP6</name>
        <name evidence="16" type="ORF">HK099_008731</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JADGJW010000997">
        <property type="protein sequence ID" value="KAJ3208404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYF4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05379">
        <property type="entry name" value="CAP_bacterial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12235">
        <property type="entry name" value="RRM_PPIL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035542">
        <property type="entry name" value="CRIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0697">Rotamase</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041968324" description="peptidylprolyl isomerase" evidence="13">
        <location>
            <begin position="22"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="14">
        <location>
            <begin position="258"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="476"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="51"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="615"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="634"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="688"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAJ3208404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="706" mass="81427" checksum="2AB286D243158C7F" modified="2024-05-29" version="1">MKFFNLSSLSVAILFTANVNSLSLNQETRLKIAEISSRLTEELNALGDLIIPKELPQQPPNNTDKEVESQEDAPQQPQPEPQPEPQPEPEPEPEQPEQPAQQPEQPAQPAPNNGNTGSSEECQVIQFTNEYRAKFGLQPVIGDTRMMAAAKDRCERVITELGSDCGHPANLGDNIISFGYDFRAAGENVDCSSADISARKAVDDWINSPPHEENLRGNFNNIGVFKCTGGNGVFDTFFMQTFGGGDNDPQFQLQFLIETSLGEIVIDLEIKKAKLSCINFIKLCKLKKYNFETFDNLKKNFTITTKSEKNISLWGYLSTDMEINNQNKYFSPELHPKLKHKKKGTVSWVTLDMEGKKFAGSKFFITLDDNLDFLDQKHCVFGKVVEGLEVLDKANDLILLDDPFPDPKNFREPSRSPSPTPSMLNQLRIDKEFEAQKNLTEEELEKLKRKENSMAQAFTLELVGDLPFAEVKPPENVLFVCKLNPVTMDEDLEMIFGRFGPILSCEVIRDQKTNDSLCYAFIEFENKEDAEMAYFKMDNVLIDDRRIKVDFSQSVSKLGLGGQYKKEKEMENTFQKRTRYKDQKEEEEYEMVFEKEGMLDEEKLKALKKQKILNHNEYEDNDNQEYNKKNKSSYSKDKDTSSSSKRDDKHKSDRKYDDDDRYKNKYDHHDDSRYEKRKNYSDNNYTSRHSDRSYSEKRRDYDRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TYW3</accession>
    <name>A0AAD5TYW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="14">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">ACA10_4</name>
        <name evidence="19" type="ORF">HK099_005632</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="14"/>
    <dbReference type="EMBL" id="JADGJW010000449">
        <property type="protein sequence ID" value="KAJ3216992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TYW3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000193">
        <property type="entry name" value="Plasma membrane calcium-transporting ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 14" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="12 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="402"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="810"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="848"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="919"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="958"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="998"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1031"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="18">
        <location>
            <begin position="132"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="16">
        <location>
            <begin position="228"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="17">
        <location>
            <begin position="868"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1083"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1087"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1101"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3216992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1115" mass="122333" checksum="8D02C3BEF4A08089" modified="2024-05-29" version="1">MVNNETQKLEYTSLPPIPLKTAVHAHHEPTIHNEKVKLIHSKLREEMDLLSSDEFGLTTEELDEICSFDNRNSESLVENLNTKFGGPLGVAIKLRTDPSIGLKTYDVPHNVKQKKGKVSPEQETPTVKKVVQDAELRQKMFGSNIIPPPPSQSIFSMIIGQIKEDPILKILIVGAIIVISLGSAICPSSGWVDGFTILIAVILVLGVTSGNDWSKEKKFKKLLLLQSDKKVKVLRNGVKDQISSWDLVIGDLVEVSPGDEIPVDGLFFSGTRLMIDESPLTGETLPVKKNEKNPFVFSGCQVNEGSALILTTAVGAHSSGGKIQLLLNEAQSQETVLQVKLGVVAVQIGKIGVAAGILTFFGLAIRWAIDWAHDVPLPPSHCSGSSSANDTLSRLQELATHFVVGVTIVVVAVPEGLPLAVTISLAFSMFKMMKDKCFVRQLDASETMGQATCICTDKTGTLTENRMTAVKIFAGEKEYFGAGSGHENAAAFTPTTLPESIKVLLTECACLNSSCFVKYKEDSPLPIFVGSATEGALLVLSEKLGVNYNQVRETHTTSENGIWDFNSERKRMSTLIEKSETTFRLYTKGASEIVFSLCESKINEDGQPTILTADEKTKVQNKIKDWASEGLRTFVLAYKDTTERYTVDSKEVETSLTFVSLVGIKDPLRKEVPGAVLQCQKAGLKIKMVTGDNILTASKIARECGILTNGIAMEGPDFRALSESEKRKVALKLQVLARSSPSDKFILVSLLKSMGEVVAVTGDGTNDAPALKEADVGFSMGICGTQIAMNASDIVLMDDNFVSLVQSIRWGRNGMTINTLIFLLIILIKKNFFATVLNSVRKFLQFQLGVNLIAIILTFIGAITSGVSPLNTVQLLWVNLIMDTLGALALASDEPEDDILETPPHPRDAPLISQKMKEYMLIQIIYQVTVLLVILLQLDNFMVPTPEHILESGHSYVTKRTSTVVFCVFIFCQCSNLVMSRKLNGELNFLGGFTRNKLFLFILSVIITVQLLAVVLAQDFMSTTSLNWEEWLLVALLAVGNFVFTFFVKVFAKNWNYERKRNLNGALSKSNLSLYQQNSNEMKKVKSFNSGKKSSEDIATSKSSMLQSSSLDQYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZK9</accession>
    <name>A0AAD5TZK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_005186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000394">
        <property type="protein sequence ID" value="KAJ3218123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZK9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="791"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3218123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1124" mass="128253" checksum="3DDF60CD5B2191A3" modified="2024-05-29" version="1" fragment="single">METNTTMNKNLVINEQDEFFVHNVNSDTPSTEYSSRTISKKNSVTSFISNLKSHSNIIENEELSSNVFESDSQSHKEVNDNDTENNNLYELSQQNLDLNLAFIQQFDNANVAIQKQLSNNSMRSINNNHTTRTDSISSISSASCLNEPLKNMPNSIGEQIHSLENTVSLNSGTSLTQPMENKLRSILTATQSSNKSLNLNENQESAALQIERTDYSDKIEFNKGILNENDNLRKKSSDMYFDIQPLTDSYENFQSRNSSLSKNNNENSTCNDSNSKGFTEAMDEKENENFEINFVTEDYKRKEVASGNNSMEDFDFKSKEEPIGFDDFDFVIRQSQTDLDLTNYAEHDDNLKESAHSTECNSLESENKLGCQTENSFLKYQNELNSESPENSNNFEAGNQFIEIDKNILYSLESNTGITAQSSLYKEPSDILPSKKNSICNLAEKKLKTTVDLKSHDKICPRSLGSVQILDETNLNETNLVDNTGKVVAETLNLETQDGQTPEQSNSSETEDIYTYTFDGSDQVELEQESEHLLDEQKLFFSEVEEECSFKVESKEKKQTFTSKEESEALSVVSTDTEGEEFLDNDLLVENSSDEDILNLSSPSEQLHKINKRYLKRFLNFKKFGINFSDRGSFEENLKKIVKALSLIRLEYGLISFENFEMLVLLGKFYLKFKYFEQAFLHSQHARNLLEMLKSENPQKFYCFKVEKICFVYLNLTYCAIHNNRLDEAQDWVKRAEATLNRSNRRNEHCYIEISKTKAILEGYSGDFSKAIEELTQITEVSTRALHKMSNEEMMLKIDDMQKIAELLEKNQQYSEALDQYNKIYKLYQNITAGEKFLGEFTMKIVNMLLKASVFENEFYDFLLKYALVAVDHLTNHIKTCSKVLQVDVDLLNAANMLLWKSYLTVNNFEGAMSVIKPCLKKVTKNSKQQVDLLLKKAWTYAYFSETKKALILIYELCNNKTTLDFIENSTILQQKLGKTLKEAIEKDGQTNINSNGCNGVREGENFFTVKKTTTANFLSAHQDFRETFNKLLSLNVDIDATRSIGGVLKKSGSVNRISLKSEQKDTRPGYIDRTSTSVLALFSLPASDNVYEFLIFVLIVPNTSSIGLKYFPCGDRNTILAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TZR7</accession>
    <name>A0AAD5TZR7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000353">
        <property type="protein sequence ID" value="KAJ3219063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TZR7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="512"/>
            <end position="513"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="543"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="562"/>
            <end position="566"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="649"/>
            <end position="652"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3219063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="750" mass="87351" checksum="8F5794069480BF3F" modified="2024-05-29" version="1">MYTTAQFNNKLILHQTEYWRKEEIAAKVAKKELLSKKEVKPNGSGLNKIKTSLVFDKLFQNALKPSKVEPYYFEGQGTPGEFEVTLTSLITVDRFPKLLNCMKTFDGPVSVALHINDDEMLNLNLYKLNNFISSNLEFIRNRLDIHVVIDKFPRQLNYLRNIARFFSKTDLLLPLDVDFIVNKNLIKNLIRNQFALKKLYSGEAVFIIPAFEFMGELKSITTFENFPQKKEQVVNLFDDKKLMIFHGPENKGHLSTNYTIWLNATESYQIESNSFSYEPYAIVNKNTVPWSDERFVGYGGNKAAWWYEIYLSGLEFWVLPNDFLIHQYHEYDDSIRVAEEDVDVNISDLEVENGVNLQEILIQPGLKKSARSRSEKIEKKLKEDEKKSKIDPPKRILILGGSNQGKSTILRQVRIAQAKAFTEEEKDHFKIIIHNNILDNMKNLLNGIEKLGLQEKYLKEICEADHHIRLISQYERKKKISKDIADILIKTWKTDCLKEAWERRFEIANIQDSALVFFEEMELILSDDYVPTNQHIVNARKPTQNITDVIVNVPKGRLQFFDFGGQKSLRKYWLPYFDNAHGILFVVAISSYYQFVEEDEFGTEKHLERDDEKDKTAAASNKLLDSLNIFTEVFNNPTLLKSTMILCFNKMDLFEKNLKKFPIKNYFTDFEGENIKRNHLIFFFYLGDDSDLKLAKKYFSKLFVKDAIKEKKAPFVHFTTSTDTKLMKKIICDILETLIRQSLSSAGFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0I1</accession>
    <name>A0AAD5U0I1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005301</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000405">
        <property type="protein sequence ID" value="KAJ3217886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0I1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041980847" evidence="3">
        <location>
            <begin position="21"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="552"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="388"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="607" mass="66371" checksum="35C2EA042E7B4CB6" modified="2024-05-29" version="1">MKFTRISSLLFLTLTSFSISAPLPQPSVVTTQDATSTTNSLVETNDSLVETAADFQTTTVAGQQESVQTTTVAGQQESIQTTTVAGQQEGIQTTTVAGQQESEVVTASEIETVDAGNDVEATGTAANNEAVASTAAEAEDDDLTPEEIATLNAQIAQDKLDLQAAEEKLKNDQLLVEQMKAEIIQAEAAAKEAEEKLAQGIIDQAAAEKLLQEKLAAEEALKDMQQKEQAQVQIINQLNVNIEVNVNILNGKEELNEELLAALEQQQAKAAAAEELNQQQIKELNEKIAQDKLELQAAEEKLAKQEELLAQKEAEKAAAEQAARDAEAKVAQGIIDQAAAEKLLQEQLAAEKELKSAQENQQAQIQIINQLNVDIEVNVNVLNGNGVDKEQLNEVEEVNQQENNEQNQQEIDQQKEQLEAEILKNEAELKEAQEKLAEQEKLLAEKEAQRLAAVQAAEDAAQKLQQGLIDQAAAEKLRQEQLAAEQELENAREQQQAQIQIINQLNVKIDVDVNKVNNVQLENSTENIQEIAQGEEVVENVQENVLENNNEAEANQENNNEAEANQENNNEAEVNQENNSLANQQAISDAFDKLSQDLLSLKNLVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0T6</accession>
    <name>A0AAD5U0T6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000308">
        <property type="protein sequence ID" value="KAJ3220309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0T6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045230">
        <property type="entry name" value="MBS1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21213">
        <property type="entry name" value="GEO09665P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21213:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3220309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="74" mass="8079" checksum="1327DB92FCF393CD" modified="2024-05-29" version="1">MVRGHAKAEAQQKNAKKLADAKGGKSLKEIEKAREAGNAIICPKCLVGMPSYKIFSQHFESKHSGPVPDEGKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U0X7</accession>
    <name>A0AAD5U0X7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004023</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000274">
        <property type="protein sequence ID" value="KAJ3220780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U0X7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12317">
        <property type="entry name" value="RRM4_RBM19_RRM3_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12320">
        <property type="entry name" value="RRM6_RBM19_RRM5_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="191"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="373"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="486"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="592"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="687"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="703"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3220780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="715" mass="80029" checksum="FAF7BAE2E8F68E3C" modified="2024-05-29" version="1">MIVEIAAAIGDSSLSRPWSKYSAGSSANEKFNAELRIKKETEKLKKKEPTIETNNNLKKKEFTEEENKKLNEFLQVMQPRSKSKTWANDDNKIEIKNSKIEKSVKLNTNDVANDYSEEKEDMFSYDIAKDEKISDVDYLKSRMKSFDSEHTVKNVSTVAEKFGEATLVSVLEEPQNTPKEIPAEDLIGETGRLLVNNLAYSATTQEVEQLFSVYGPVAEVHIPIDKLTKNSKGYGFVLFLIPENAVKAYSALDGSIFQGRLLKIIPAREKVLPEDEDDAKISFKDKKEKQLRKASMKNEGNWNSLFMNSDAVANAMAAKLGVKKSEILDPASENMAVRLALSETQIINETKEYLQEQGVCLDAFQSNRERSDTCILVKNIPFTTTVSDIENLFGNYGTLGRCVIPPTKTVALVEFLEANEAKAAFKRLAYTKYKSLPLYLEWAPTGAFNSKFESTKKKNEIAITNGTTSDLLLDDTKDDPDMMPVATLFVKNLNFSTTEQQLKEAFSSLQGLTSTRVATKPDKKDSSKKLSMGFGFVEFNSKENAVNALKAMQGFNLNGHVMQIKFSNASIKSSSGENGKGNKKGEIKVKGTKLIIRNIPFEATKQDIKQLFRSFGQVKALRIPTKIDGSHRGFGFIDFLTQQEAKAAFEAVSSTHLYGRHLVLEWAKDDDSVDAIREKTRKNFNSNEIEEDKRKKRKVVLGNDEDSAMGGIEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U121</accession>
    <name>A0AAD5U121_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3668 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_005458</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000425">
        <property type="protein sequence ID" value="KAJ3217480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U121"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010564">
        <property type="term" value="P:regulation of cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039893">
        <property type="entry name" value="CEP120-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022136">
        <property type="entry name" value="DUF3668"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21574">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 120 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21574:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 120 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12416">
        <property type="entry name" value="DUF3668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3668" evidence="3">
        <location>
            <begin position="180"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="335"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="686"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3217480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="848" mass="99566" checksum="92494141F9BFEE95" modified="2024-05-29" version="1">MQKRSLLYSKTLSKIVLSIPLFDTELAWELDTKALGFLRSQRASLKMVLYSILPNNRRDTLGYIMLDLRGASQSTPATEKWYPLINSKQGGAFRPEIKISFSVTPSSQLMETTKEIPLKKQPKLNSSTQKQILLPTNFNVKVSNNNNNNINNQIKFEKIGENFYTIFNNASEKHFDKNFKIWELNITVAFAESLRLLLDTYRPNLSRSSEDGFHFLINFLESDFTTEKFYDLDNPIFNADGYCIKFKSSKENLISFFNQSSSFVLYLCHKNQVVGLTHVQLTTLINNFQEKSASIVEKVYNFFDANEQLPISHDSKVPNIGLSLKLELFNEEDNDKNQTYENKNLNFSPTRSEKSFASEQNQESPKNSLQNNFVKTLPKKKNFLENPKENFKVKPTENDNNTFINQKPQQEIKIQKKKIFNFNDKKVWRQYRFSIDFLCLTNFNLEEDCEIFMKYSYQPFGTNSFIKTSTISVLKEQKNEAIFLPHCFSAFEFIMSFERLKTYLDGVPLVIEVWKKGYGASSDVLLGTTTIDLSEVLNSPKEITRSEDIGEFLMQTCENKIGTVIGSEEYSYKKITDLKMNLSLEDFGEALTTREEENEEGEVDYNYETKFNDSEEKKAQYLSENMMEEIPSLKENLEYKTSLELEKFKKKEEEKFKLMMLEKERLLMQKFSEEFKKREKEREAILKKKIEEFRTLEQQLHNLLFELEVDQARRLHEEYTHQMELEKKKCKEYEIQNLKILKEKENVEKELKSLEKEFVQFKLNLNQTPESILNSDLLKMKEEKYGSYKNDDFFSSFDMDENIDPKVMEEIDRLIRERDGLLSTGVYSKNDLIIVELEKRVKSLINSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1H0</accession>
    <name>A0AAD5U1H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Man1/Src1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000246">
        <property type="protein sequence ID" value="KAJ3221179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1H0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12935">
        <property type="entry name" value="LEM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044780">
        <property type="entry name" value="Heh2/Src1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011015">
        <property type="entry name" value="LEM/LEM-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808">
        <property type="entry name" value="INNER NUCLEAR MEMBRANE PROTEIN HEH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808:SF2">
        <property type="entry name" value="LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="61700" checksum="8BD7CB6E070F4F15" modified="2024-05-29" version="1">MFDACHLVVLTTKPEYLEDDFDPNKLKIRELISILSRYDIDLPSTLKKKQFYVDLFNNELKTRIDQLQYQPYLRREETTIEYVGFTEREESSNPDGRNVFEESCSESSVQDEEQEDTCNNNLRNYFRRSPEIRLNVFDGRDSPRGVQGKVKAAQNTFENLAKLEREKVAKEYKKYLQQNLQDDYNNSPEFFTARDESLSKFDEKIIDELILEYLNKEVENNPDPSDETYNADYFSLQKGGETPQFFIEEDVSTNEEERIYTTIQPDNNYGINAVSWNHFYISLIVLALAFTSFAIFERHYHSLRFCADDRYVGCIRCPAHSICSEKYVLNCEENYSFSNNHFNNIIFYSGWPVLNSLQTTCVQKLKPTKVTVELNNLTNQNENEDYTLVRNITTPPKKFEGAATNTSFNDLMFSIKNRIADSIVFFFKDHRETLWVSFDFIKVHISSLLREKGTSRIGTEDDEGGFIKISDLKDEIFNDSNFDSYFNKKVWSNIVQNIRNSGVVVEKRTEAKDEDVLMWRFIEADGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1H7</accession>
    <name>A0AAD5U1H7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WD repeat-containing protein wrap73</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">WRAP73_2</name>
        <name evidence="1" type="ORF">HK099_005528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000434">
        <property type="protein sequence ID" value="KAJ3217298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1H7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990811">
        <property type="term" value="C:MWP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990810">
        <property type="term" value="P:microtubule anchoring at mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052778">
        <property type="entry name" value="Centrosome-WD_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220">
        <property type="entry name" value="WD REPEAT PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN WRAP73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3217298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="330" mass="38419" checksum="33F981EC7B5D57EA" modified="2024-05-29" version="1">MEFSELFKQSKNLCKFSPNGKYLGCIIQYRLVIRNAHDLEIVNLFNFTDNLQAICWSRDSTLIACASFNLGSIQIWNLVDPNWSCRIDEGLGGLTKILFSPDSRHLLTFSDFQLRITVWNLINKSVRYMQYPKFDNKGFCFRKDGKYFSLVERKECKDFISVFDCEDWEMVKHFQTDTFDLEDIAWSPDGRFIAAWESSLDYKVLLYFPDGRLVSTFSREITGLGIKSVKWSPSAQFLAVGGYDKKKIYQEVNYETKLNSFDTSDKIFENLYNKTRKGYELVDVEKFPFKIPILKLIPEKPNPKMGVGLLEFNCDGRYLVSRNGNSLEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1P8</accession>
    <name>A0AAD5U1P8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_004948</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000367">
        <property type="protein sequence ID" value="KAJ3218715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1P8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF20">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB-7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0636">Prenylation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3218715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="405" mass="45769" checksum="113C309B03432E67" modified="2024-05-29" version="1">MDVIKIVMLGDTGVGKTSLRNRYLHNKFSESHKSTIGCDFITKEVINNKGKAISLQIWDTAGQERFHSLGTSYYRGSDVLILVYSMTDPQSFKNLKSWIKLFFKNLKVTKIEEVLNFPIILIGNKIDLESEQIVLKKDAQKFSKEILKEIFLKEGEGGLVKMKNMKTLKKKSSLATILNFDLRNVKKKFSLNSFKAEHEDNELKNFNDTSQKISPCKKVVMTKYDGTLNFLEKWSYTDKIEENNNKFLKHTISNTSMSEVSSIYGTAVEGDNSLLSNSSTGTGGDEVNPSCRTPQKKNIYNQTPDSSTLGKSTLPKEVSFNSFLNIKDNNGQESLVEFPTFLEFPEIPFFEASAKSGRRIDDIFEYIANVVNVDSTSGTFSEAINDTIFLENSSEKQSKINTCYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U1Z8</accession>
    <name>A0AAD5U1Z8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000229">
        <property type="protein sequence ID" value="KAJ3221455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U1Z8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="30291" checksum="664F913829FFA75B" modified="2024-05-29" version="1">MPYTIKSSYENKLRKFTLNDVPQTFKEFNDSICALHEISFPVTFSYKDEEGDTIYFDNLSELSQILKPNTTLKIFIEIRTPPPHTQLFSNDTIYPNLDEIEAVPSYAESTQDINSVGTPSEANDHTAPTYAWGQKGKEIEISNPKVSEPEKINIIHENNVRETSDISLGEKNKVFTIIYGNKSTKNKVTISKKHFYDIWELLLKVYQLILPILAVFWKELKPIAKKIYEEAKESQDKNKINNGKGDVRVDVGSSSGSYISIKKGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U226</accession>
    <name>A0AAD5U226_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000296">
        <property type="protein sequence ID" value="KAJ3220506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U226"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="598" mass="68930" checksum="0A262B201CA305F7" modified="2024-05-29" version="1">MRRLPSFSSSTNSLISEPNDFQAILEEPPKTSKLTELSTLYFALRTVILDEQSEQTGQLLENFNEKQQQNLKKSSLSSIKSNSKDYMEIDSPDESPTTPQTPPFTTSDASLYNLSCNSAFNKRKRDFEMIVVDAKTRRLTNGLTSRLDRLHVEEIDTEDTKNFVNIGLGEGSFAGNESHQKISEELLELNNIVFEKRNSDVQINFKNVEASADTTASPQNFEKFYQVENAFSDQQIRMLKAINLQKKLPEEFFFQTWMAKKLELEHNLGFLQNDTFGVLTGASDSYDDIFLLVKKIVESAEWLSNNDLDNLVHLVPLWKTLQSNIKNFMTYINLVEEMKKTIKINLNLNFLVDNTQNYTIEEFELNFQSLVEIFKEKKSYFKDFVSNGGEQWISLGFPMNKELLDNFKSWIFNINLIVFLLFENQFNKGFYENGLSDARVTKTMKLILNVLNFTATCVAFNEVTATPKNLVDKSLLLSNVYCRYCLSILEKLETRKNSASGGEAKIVLIFENLTNLVQDLEVIMLHQKFIKSDKKYKCVSYSEEFLDKTIKEDEEEKESILKTIFQKLLEIGLILCTEKELEFEQNIKVLTSMIPSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2E4</accession>
    <name>A0AAD5U2E4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_005479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000429">
        <property type="protein sequence ID" value="KAJ3217385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2E4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3217385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="432" mass="47410" checksum="F2A25D6E93A4B113" modified="2024-05-29" version="1">MPMPMKTQQYPASNTQSIQAKVSANQLVNSMMKANGQKGAVVSSKSPAKSGNTEIDVLRSLNKAQFNQIQVLRAELQKEKKLCSAMNTRILEIEIQMKQEIQRASQKPLMVGKAAQQKKPVSPIQKQSSNQKIMNNYTNKNTQSKTKSNSSPISGESVWESFFEAKSPSTQKPKMQKTQATSAPKVTATIRPNTVQQKSSSPKSSSPSNSHPNYENFLMPSMFELPAAYMNSLSPASPVRRSPTQKSPTQKSSSQPMDVLSKPKSATQKSTSAKSATVKPASQQKSSVGLKSSKPVSPSNSNPNYENYLVPALFDLPASYVKCLAPASPVKRSPVSPQNKSTFWSVEQKSENKPAFWATEPKTSSTQQRPASPQQKPAATQQKPAATQQRPASPQQKPASPQSKSTFWSVEQKTAEPKPFSNHKQQRFTMYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2K7</accession>
    <name>A0AAD5U2K7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nitronate monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000185">
        <property type="protein sequence ID" value="KAJ3222232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2K7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF20">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="35695" checksum="A785DB636F0384D2" modified="2024-05-29" version="1">MPIQTKLTKLLNIKHPIIQGGMQWVGTAEMASAVSNAGGLGILTALTQPTPEALRAEINRCRKMTKNPFGVNLTILPSITPPPYAKYVSVIIEEGIKVVETAGNNPGEHVKRFKEAGIIVIHKCTAIRHAKSAQKMGVDLVSIDGFECAGHPGEDDITGLILLAKSAKALSIPYVASGGFGDGRGLAAALVLGAEGVNMGTRFMCTEEAPIHRSVKEAIVNATEKDTALMFRTLHNTARVFKNKVSLEVVKIEKKPGGASFDDIKDLVSGQRGKKVFENGDIDYGVWTAGQVCGIIDDIPSCKTLLERMVKDCETVLKEKHSLIVEDSPSAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2M8</accession>
    <name>A0AAD5U2M8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000181">
        <property type="protein sequence ID" value="KAJ3222317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2M8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10391" checksum="B640BCCE1B724C1E" modified="2024-05-29" version="1" fragment="single">EKKVESIKTPFKSNLWIAMVLLSLIPFLVMTYSFDDESEKIGESLLLYCLIFGIPFLACLMTGYFSRSFEEMNETLKELEREKFKYKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2N1</accession>
    <name>A0AAD5U2N1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000532">
        <property type="protein sequence ID" value="KAJ3215600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2N1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031126">
        <property type="term" value="P:sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000397">
        <property type="entry name" value="RNA binding protein Nrd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048892">
        <property type="entry name" value="Nrd1_Seb1_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051485">
        <property type="entry name" value="SR-CTD_assoc_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140:SF4">
        <property type="entry name" value="PROTEIN CBR-NRD-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140">
        <property type="entry name" value="RNA PROCESSING PROTEIN LD23810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21380">
        <property type="entry name" value="Nrd1-Seb1_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CID" evidence="8">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="396"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="338"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="778" mass="86041" checksum="E8BEF8977D78F75E" modified="2024-05-29" version="1">MSVKEIIVFDKLLYSLTESKPPVSASKITDLTKSALKYTKVSKHIVSSVEKFIVNCSPEYKLSGLYVIDSICKAAQKVNTPESNQYPKRFNEKIEPIFSSLKNAPAKDKEKIRRLSTLWKKSPFFSSSSLEKLEKKYLPESSAKGKEKTSDRSSRRDSKKDSDSPEETSSELASDINTTNSEVLNTLAALTKSQPVPAIVNHPQSAGNVELMSAILQAQGVSQEQLISVIMNAQQLQQQNIPLPSQNVLAAGSPFNCNEEDSKSLSSQLQMLSSVLLPNTQIANQQTVGQTGSVNPTSWMNANNNAANVTGTPTNDSFAAFQNLMNIQSGNLLGLNQTAPTSNFNSSENLTNSQSNFSKVEEKGKSKFSDPGDPPYCKEAEFGVDVPPNHIKVLSRTLYVGCVNKEATKENLRSTFEEYGKVQSVTINYDKYHAFIKMGTRDEALNAHKNLQSKLVGESCYLRVKWGVGFGPRDKFDFEKGESILPIDALTLADKNTMEKSARGGGKCLSQYVMEEPDLGNPLIDSAHGTPSYPPNHETIVRQQKMLQAQQPQFVQQTQPGFKKFNNNMGFNNKNSQNNATFQKNNNNLKQNYNNFQNPKNFPMPKRPNNGGFKNLIEGGKISNFGMNNNGEKPSFKNIAQGADGLKPHMGARGNANSSPDLMMKKNFHYAAQQNFLQQQQQMQQNFFGNPADNYQNYQNFNNFGEDDFNSNVKVLGGGGGSGNLGRGGNVEESGYFYDGMLDNTKKRLNNEFMNQESHNDVKVLGKGNAGYKKARVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2N9</accession>
    <name>A0AAD5U2N9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coiled-coil domain-containing protein 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CCDC12</name>
        <name evidence="3" type="ORF">HK099_002754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000194">
        <property type="protein sequence ID" value="KAJ3222053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2N9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013169">
        <property type="entry name" value="mRNA_splic_Cwf18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31551">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08315">
        <property type="entry name" value="cwf18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3222053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="174" mass="20135" checksum="E26130A0CCF6F645" modified="2024-05-29" version="1">MSSLQNEVAERKKRLAEWKKRKQEGTSNKKQKTSTNGNTQTKDTFIDVINFRNYTPSDKRDVDQDDYKGLQNSTKEAKKTNDIIEEVGAIEKQVKEFENDAKKAEESRIKELDLYNLAPKKADFDLKRDLDKKLEKLEKKTKSSITQLIRERLKASGELTDGKDNVNNSFSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Y1</accession>
    <name>A0AAD5U2Y1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sulfate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_002105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000168">
        <property type="protein sequence ID" value="KAJ3222593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Y1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF4">
        <property type="entry name" value="AFR304WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="549"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="808"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3222593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="905" mass="101676" checksum="60B66E466127EC6F" modified="2024-05-29" version="1">MTDKPENQTYSNHNLNIVLSRKSSSRSSSSSNASSSSARFPTEIRNIDSYSSNLTALCSTSEYNTDLTEATPLIKKDENKNQKPTKQSKAKLIKTSCSLALYSVPAVILGLILTILDAATYGIIVFPVADYIPDSATQAGISMFLSSTFVSQLIYTFGSEFKGVNGSMMIEVMPFLHLMCSTIVNMIPEASDEAKMSNIMLVYAVSTLLTGIIFLIIGFFKLGNIISFFPRHILIGCIGGIGVFLFVTGIKVTSRVTAGLGNYDDLLKLFEPKILMLWSSSLILAISLKCIQKKIKHPLFVPCFYSSVNIETLRLSGWLFSLPKNNGEVPFYTYWTYFDFSLIDVEAFFACVPTILALTFFGILHVPINVPALSVSTNQQVNINTEIVMHGFSNLFSGLIGSCQNYLVYTNSVLFFRSGGDSRIAGFLLTVAVGICFFYASSVILFVPVIVVGSLIFHLAIDLMIESLYDTWSSEVSNLEYLTILVIVITMTGFTEGIVAGILMACVLFVYNYSQRSVITEVTDGGEMRSTIHRPYKQQKYLDLVGSQVKILSLRGFLFFGTINQVDSYVRNHYSTEGFPYKYLVVDFSLIETVDLSAIEILKNLNIWLNDLGVKLLIVSGGGSGKEKLIHALDSNDNIEAGDAFNHFTTLEEALRFTEAELLEIYFQNLKKIEEQKKSVPASPSRDITHSKTSNDLKKKDFFNDDTTHFSPRTKIITNSAKEVLENYDDECEELAGDKEVEFKFLFDTFYLILKENQNLTRDEIYPIINSWYQYFEKVKFSKGVELWKKGYCLTIFISNFLTIDVSSDTSEVLYIVESGQLSKVNNNRIIESLFTGTMVGELCFFTEQPRTCSLVVSEDSVLWKMRKADYEKMILESPKHAVNFTRMALTFDAERMYTIVNRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U2Z4</accession>
    <name>A0AAD5U2Z4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000179">
        <property type="protein sequence ID" value="KAJ3222359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U2Z4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041931690" evidence="1">
        <location>
            <begin position="18"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="90" mass="10027" checksum="8037F56E69F37DE2" modified="2024-05-29" version="1">MKIIAILALMLLSKVQSTPHNKNAYKHNKLTRTNKKQLQFETQPCTSTSLFISVTTTTVNDSALETVFFSDVGETDAKIISDDPNNLLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3D2</accession>
    <name>A0AAD5U3D2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DHX33</name>
        <name evidence="9" type="ORF">HK099_003447</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000226">
        <property type="protein sequence ID" value="KAJ3221502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3D2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000767">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF118">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="97"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3221502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="534" mass="60822" checksum="25662100BDC4C257" modified="2024-05-29" version="1">MTDEFQTNRFRSYSIIILDEAHERTLRTDVLFGLIKNVLVERDDFRLVIMSATIDADLFSNYYKNSKVLYVAGRQYPVKIFHSIKQQEDHLDATLITILQIHKEEQKGDILVFLTGQEEIENCEKILKDTVKFLPAECDTLLIRPIYAALSNENQQKVFEKTPDGCRKVVLSTNIAETSITIPGIKYVIDCGLVKVRNFNSRIGLETLATEPISQASAGQRTGRAGREGPGVCYRLYTEEAYEKLEVSQSPEIKRCNLTSVLLLLKASGVEDIFNFDFIEKPAKSNIISALEQLFALGALDENGELTEEGKLMSVFPVEAQFAKVLIKSKEYACSNEVISILSCLSVDTLFNFPNDKKEEVTLALKKFNNYEGDHLTFLNIIKEFQSQKNGFDWCKENYIKFRSIKQALVSILTTFLFQPYYVHQDVQKQLIDLCAQNNIPVTSTSKNENILKCFLSGFFQNVALKQTDGSYKSLVNNQVVHIHPSSGLFLKGADCIMFNELVHTKRKYMRNCSILQKDWLYEIGGHYLSRNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3H1</accession>
    <name>A0AAD5U3H1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HEAT repeat-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HEATR4</name>
        <name evidence="2" type="ORF">HK099_001735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000152">
        <property type="protein sequence ID" value="KAJ3222929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3H1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019135">
        <property type="term" value="F:deoxyhypusine monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697:SF5">
        <property type="entry name" value="DEOXYHYPUSINE HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697">
        <property type="entry name" value="PBS LYASE HEAT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1081"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3222929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1195" mass="136807" checksum="BDE0687189DDC4F7" modified="2024-05-29" version="1">MPTTLIDLVEATINGKSKSKSLGYKEVVPIKPLSDQKVRNYSKPTRKQTLRKYSAQTRRKNPIVEAMDGPVHQIHGASVFRVPPILPPVYETQLKEINEVLRGIKSYNKMVMNDSSTNKENENKNSEFKLKFNEKVIKERCEWPFGMDILGNEKKKEVVGTKFERHSLKDNELLNFIHKSSWKNEATKKHFLSKFKLEDNCKLITVKEKNFEEIKFHDLENCNLNNERGILSLAAKICSSNKTTDSYLTRNVPYMLEVWQESEKVNLEKLLAENTSHDDEQKKNNKEKIIQAVERLTSATGQKEQEIDNFLKVSKRLRSKSISCSNQHPSPEINLDSSFSSSIKENEEVKDSKISLIPTVKEISNSVIVPTAVNQDSINKKTLSKSTIKLLRKLIKDSINEQGLTLQATPSNIDFLLRTTLTGHSGIGQDATQKLNEVATATRSNETKRQEKRKSLARKSKTGSPSVGKEGEYLNNSINVDLNEETLLEVKDQDFKLILPPPEAEDDGGGDDIELEADDFEIDEDLKNLNKTKKNNLLHNNELNLEESRTKTQDKDKLKKIILNAKLTNDTFKMRQNLSLTQNVENDDFKVNDFIKEEEDTEAFNLNHFVGEVRLLTNSSSHKEKEKSNPNNLTILTLSDFLYSPYKNLNQIPHFNTEAYSTLFHVLSLALRECDHKQLKYEAVKLLLQLKATQSLTRWDALTFRETLRDMLRKGSEDEKLLSALSLIHSKQIDYISIKTVVEYGLGLLQLSKTKQVKEVLLSLDKKYLDCLEMLEKWVRMLAENVEVGTPINFNTINPLYQNPVNMAVQYFLDLMWNDWSSVVRTTATNILAHLGVGKPVFDWIINLLSHVDPNKRIEALSCFGQLKILTNQSMMKFLNTFDDNFTDVRIEACKVACVLATNHRLLINKLIEKCDDIEWKVRAYAIKALGLSGYSGPKLKETLLWLLYHEPHSSVKAEAIRATFTIMRQEDNLELKEGIYNLLNDKSDLVRKEAERVLQQTGFSITPPAQKVISKSNAKKEFEELETDEINSSLEKNSKLLTSEGHKVMTLSENSNAIANTMPLNLNQSSSHNAKQSPRSITRKKKKRSYLITPKNNKIEEAEKQKILSELEAGNSNKGYPHKLLNMYNGHTQEEIEIILRTTLVTEKELEDVIFQVKDMAKMENILTEINSSEKTSEELWKEELTNNKIKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U3L6</accession>
    <name>A0AAD5U3L6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_003366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000221">
        <property type="protein sequence ID" value="KAJ3221579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U3L6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3221579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1040" mass="121764" checksum="3FAA1C9CBD45CB4C" modified="2024-05-29" version="1" fragment="single">ISVNNNIQSFIRNLSNSTKSVEILDENLKQQFVIEKENKKKNNSTKNLSTEVCKSLQDASLMKFDSQISCSAFGAVFDEKKKKVEELTTEFGKLGHKKFDNLAHNNEKMTNMVKANRLKEASIFFIELSKRNIDLDEKVLEYFFRTILKNRSLTDLYSLGFVPNVKIFTFLIKLHSLDKRYLYGDKGRKAEFYYKELIGTGLKPNVEIYSHLITAFHLLKDFPKINYYHDKMVKDNLDPDIAIFEVMIYQNRANITEVEKLFKKLKDLNLEPSLNIYTSLITAYGLRKDLNTANLFYEELKTKKQKFNLQSADYTKIFLTFSKDLKYFEPILKDYDESGLALDENLRKLILKSLPKSGIEDWEILKKKFSKGIDPPISLHSSEISDEKNLDLIRENIAEKCATVRNVASSAVDTKISDEKTKVVLSPSVITAKKNVSGKIQSALVTSFQKLIAPPNQLDAKEHEIHLQDLISRGEVPDRLTVKHLLTVYRRQRNTIKIQNLYDTLISLNQKPNPFFYHSLMFVFSQSKNRQDLGKVEHYFYEMLSTGVKPRHVTFKIISNAFQNKPLKLSELYTEIIRQDLPKEDYNKILNSGTWKSKYFDFEVFYKALTTKNKNFVPDIETYNILLDRFSKQRLEEKFLFYFEELFARDDLMPNKDTLCHLKWMFNNNLDKFKFYLSYFKKCELSTQDINFALVYSKNEIDLMDAIYEKFVLEFKCCTPDVLTITYLMRSHGRFESKAASTFYYNELLRFKIKPNSFFYLTVMQGYNSYTKYKSPTLVEHYFNLMIADKISPTINHFAVLLSALKSDDNKVYHYYKKMLEDYPKLQPNNHIFQILIDSAKKNQNNLKSKYIFDEMISQGLKPNAHILNSLYFENFDYSGDLEEKLWDILNRFKHSNVQPDKRTWTEIIKVLTVAGDYKNAYRIFQALSGTLYKHETPPNLLFEVKYDPTALNSALFCVILDTCKLGNMEKEFNKIWKFCLKSNYQLNSNVLTSYIEGLVKFKRFKDAIETILEYSKVENVSLHVIGRRVKPDMGSKVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U487</accession>
    <name>A0AAD5U487_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_003612</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000239">
        <property type="protein sequence ID" value="KAJ3221285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U487"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3221285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="223" mass="25558" checksum="30AD2678ED287692" modified="2024-05-29" version="1">MQQINKELEKNNCLGLENGLINSSQDSLQTLENFDLYLPDIVQVDFLTKQNLSRANSLLSPTFSETSSDSLSTSHNSPLLSSNFFSQENYSRNKDFLNFPIINNQHIPCSQADNFTLPLPLVDPNEAITITLMQLSLLLQIPINNIWKVLSQPKNFDFTKINISNDTQDSIQQNTTTVKKKKKNRVEHLCPECGKVFTRNFNLKQHLISHARKREKLIKKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U4P8</accession>
    <name>A0AAD5U4P8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein tpx2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TPX2</name>
        <name evidence="11" type="ORF">HK099_004763</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPX2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000346">
        <property type="protein sequence ID" value="KAJ3219245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U4P8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060236">
        <property type="term" value="P:regulation of mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027329">
        <property type="entry name" value="TPX2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027330">
        <property type="entry name" value="TPX2_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009675">
        <property type="entry name" value="TPX2_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14326">
        <property type="entry name" value="TARGETING PROTEIN FOR XKLP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14326:SF44">
        <property type="entry name" value="TARGETING PROTEIN FOR XKLP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06886">
        <property type="entry name" value="TPX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12214">
        <property type="entry name" value="TPX2_importin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPX2 central" evidence="10">
        <location>
            <begin position="268"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="TPX2 C-terminal" evidence="9">
        <location>
            <begin position="513"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="530"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3219245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="592" mass="67775" checksum="E8473DF13CC391D0" modified="2024-05-29" version="1" fragment="single">MVAQRVISEKVNQKLSTSTRKSNFQIKTQKSTYPNDNFDDAVTIDKKYELDAPKYFDFKVEEAENYDFEAADDWFAYKKKSPASVKSKRSLSIKNSNSLKSTIASVSASIVKAATEAEEKLDKRSTLRYLPTRSVKPLTIPKEFNFSKAKEKTILNKTASGVSSGKVEKTKTKTTKKSNLLTSKPRLSARLAAMIKANAAKKKIIAKKEAEITIPKPFQFHSTLKNYKSNVNLVPKSPFKPLVLKIKEFEETKPDRFKTEPKKSKKQELTAPKSPMLLTKIRSKKTNVPSSAEIELQEMKAIKPFKASKLNRKVYTMTQLLIKTYIIQILDADHPLGVPPQNKLELTCPVSPAIQKPKPKPNPEPALEALFKANPVKLTEPFEPVYEHKHTKPLLKTLPGMKISKKKLQRFKEELRKKEEEELNARNFVANPIRSVTPDEFPEREVHYTDPEPFFLKTDERGEIIQQKFKEKLCKEEEERIKKAEFHANAAPKAAPFYPEKSSKPVTEPENVVLHTEIRGKERKAFDDGIKKREEEDNELKELLKLKQQEEEKVQIKELREHLVHVAQPIRHFAPTVVAPSQRKLTEPESPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U589</accession>
    <name>A0AAD5U589_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000298">
        <property type="protein sequence ID" value="KAJ3220486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U589"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3220486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="297" mass="33932" checksum="9238B1016C38C13E" modified="2024-05-29" version="1">MQQDFSTKKRRSYALNQNTLSKKLSDIQLGTAALKLKLKNLFKTNDIQPNNKYNNWNHFNLSNSDTNFDKINANPNLTDSALSQISVLDYPPLSKTSSELSLVTTTTKETTSGYNGQNIANSNSSYPNESQNSLPSGSPVVNLLMEKVVAESDNTHLPIIKSKLTCCEIKNSVKQKSILKRTSLYEEVEISPENLNKLVLKTNLKKKKKLLFNEVTDIFETWSEFDYPRLGVTEKSFEISDDEEFRDLMEEEGELMLLNYNCNNIDEFSYQADNRETKNGIVSNWNRLVLQKKSDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5A9</accession>
    <name>A0AAD5U5A9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MTHFR SAM-binding regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_007648</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000076">
        <property type="protein sequence ID" value="KAJ3224928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5A9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="8">
        <location>
            <begin position="270"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3224928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="553" mass="63011" checksum="7E143CC751ABE6FA" modified="2024-05-29" version="1">MVRIDTKIAKALNEDRPFWSFEFFPPKTEIGVMNLYDRMERMYALGPEFIDVTWGAGGSTSDLTMQDAKNCGIKNILALRGDPPRGQANWVKVETGFAYALDLVKYIRKEYGDYFCIGVAAYPEGHDDSLDKEDDIKYLKLKQEAGANYVVTQLFYDVDFYLNWLEKCKEAGITIPILPGMMPIQNYGGFQRMTFQCKTRVPKKILDELEPIKDDDKAVKQYGIALGIEMVKQLQANGVKGFHFYTLNLEKSVRLILEGLKFVAPLSVIKPLPWNPSLARNREKENVRPIFWRNRTKSYILRTEAWDDFPNGRWGDSRSPAYGDLDGYGIALKYPLNECLESWNHPTSVYEIANLFVKYITGDVKFLPWSDSPLALESNTIRDKLEAINSAGFLTINSQPAVDGVPSSDSVFGWGPKNGFVYQKAYLEFFVAPEMLSKLIAKIGTYPFLTYYAINKLGDLKTNTESDSTTAVTWGVFPGQEIVQPTIVEAVSFKAWKDEAFQLWKQWGGIYPDDSPSSKIISEVYNNWYLMNVVDNNYKDKESIFEVFHGLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5F8</accession>
    <name>A0AAD5U5F8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_002601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000188">
        <property type="protein sequence ID" value="KAJ3222168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5F8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF2">
        <property type="entry name" value="OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3222168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="476" mass="54454" checksum="5D1DCF466DE24DAB" modified="2024-05-29" version="1">MTDSTNEQNLNVIDDHSPATEETEDRLNFPTKLDIETSLNVFKYFWEFPEKKSEAATNLALRELFEITRLMFAPTKKEREKLQKEKKNLKKKEDQLLLNQSLIRTNRNFKLVGSNVTKGALLASGSENLEYPPKRGDLNEINKFIVDSDAKIQEDLKLQVGEAIMAQKNFESEGATVLATTRFPHDAAKRLSKEEDFISFKDRIILFGLDFRDISMVHQFCAYVKKNFTRLDGIINNAAQTVRKPPSFYEHLIPFEVEELPEFISTCVKIVFINNGNENYYLKKHNSDADVNENQVSVIRSSIQVKSTSALMSQLELIPSDKKENNKILYPEGLLDRDDQQIDMSKSNSWKSLLGEISTVEMVECHAINTFVPFILISELTNLMKSTINSPIGSSGDKKWNKYVVNVSAMEGQFYRKKTDQHPHTNMAKAALNMLTRTSSSVLALDNIFMTSVDTGWITDENPIDQWYEAEFIKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5K6</accession>
    <name>A0AAD5U5K6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HK099_000561</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000113">
        <property type="protein sequence ID" value="KAJ3223900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5K6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000524">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000121">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="82"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="370"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAJ3223900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="569" mass="65947" checksum="A8FB302F613EFCEE" modified="2024-05-29" version="1">MTDAQCHQEELKVERKTTHSTSDKLQSVTFFLNNLFFSSYYPSVTRIIPNNPKQINQLYFDNIAKLKSIASLNSLKVSPKDFEKVKIIGKGSVGKVYLVKKKCDQSLYAMKVLSKSEMIQRNKVKRVLAEQEILTLSKHPFIVTLYDSFQTESNIYFILEYCAGGEFFRTLNKRGHLKEWEAKFYAAEVISALEYLHLHGFIYRDLKTENVLLHQTGHIMLADFDLSKFNNLVPYPVLEKTHFKSYFGEKDFYYLDTHSSCNIKTRSFVGTEEYMAPEIILDLGHTSSVDWWSLGIFIFEMLFGKTPFLGKDNDETFDNILKKEVKFLNNIQHVSSKVKNLITSLLIKDQDLRLGSQFGASQVKLHPFFKGIKWDLLRNMTPPIIPVLKDRFDTSNFYRYNDNGPNSLNLENECCVSQKCSSFTSNTVVADSTADGSELFDDPFVDFESENKQLIRIFCTLYSLSILATSLILVFKLSLEIFEQVKNSKSCYKKKEHEKEDGDLIFFSLTNKNFSSDLEKNKNNTFYKFMETAEKKPDFCAFNIYPVLPKSSANIRGKNPQQWRKYKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U5Q5</accession>
    <name>A0AAD5U5Q5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease H</fullName>
            <ecNumber evidence="4">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RNASEH1</name>
        <name evidence="11" type="ORF">HK099_007155</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4"/>
    <dbReference type="EMBL" id="JADGJW010000067">
        <property type="protein sequence ID" value="KAJ3225237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U5Q5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09280">
        <property type="entry name" value="RNase_HI_eukaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000115">
        <property type="entry name" value="Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.970.10:FF:000001">
        <property type="entry name" value="Ribonuclease H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017067">
        <property type="entry name" value="RNase_H1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036852">
        <property type="entry name" value="Ribonuclease_H1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="10">
        <location>
            <begin position="79"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAJ3225237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="232" mass="25716" checksum="BD8574E1C33C00F1" modified="2024-05-29" version="1">MPKIYAVKQGRKPGIYQTWDETKAQVLGFPKAQHKSFSVMSDAIQYLEGESKSLEAAYTTDLPIVTNSIQPIPYKENENGEVLNIYTDGCCINNGRGGAIAGAGVFFSLGDPRNISERVPGEQTNNRGELLAAIRALEVSSYNVALTIHTDSMYLINGLKGWIANWKKRGWKTSYNTPVLNKDLWERLDELNSSRKSVEWVYVKAHSGILGNEEADRLAKIGAYLPAVKSCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U643</accession>
    <name>A0AAD5U643_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Globin-sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_006123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000051">
        <property type="protein sequence ID" value="KAJ3225825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U643"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01068">
        <property type="entry name" value="globin_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039379">
        <property type="entry name" value="Protoglobin_sensor_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071:SF1">
        <property type="entry name" value="GLOBIN-SENSOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42071">
        <property type="entry name" value="PROTOGLOBIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="Globin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Globin-sensor" evidence="2">
        <location>
            <begin position="26"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3225825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="243" mass="27627" checksum="F77906813F85FA37" modified="2024-05-29" version="1">MNVQSNNTATVIDPTKLKSHKNDILYRFNYVRDFLDFNENDIKAIKLSATILAPLVPQIVDLVYQKLFSFDVTKQIFLQRNEGFTGNIEKNLSSLNLSSDVIKFRKDMLSKYLVKLVTADYDEKFVNYLDWVGRIHTNTPLKKSKINVDYVHVNALFGFVSSALFQIVLDSNLSKKEQDSIVVAFNKLLWIQNDFFVKYYSKDSVEESVQQSKLSFKSHSGLLCCVGVGVAAVGVAIGKYLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U675</accession>
    <name>A0AAD5U675_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial transcription factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SPT3</name>
        <name evidence="14" type="ORF">HK099_008461</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the SPT3 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000093">
        <property type="protein sequence ID" value="KAJ3224441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U675"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22926">
        <property type="entry name" value="HFD_SPT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="entry name" value="Ribosomal RNA adenine dimethylase-like, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003195">
        <property type="entry name" value="TFIID_TAF13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11380:SF16">
        <property type="entry name" value="TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02269">
        <property type="entry name" value="TFIID-18kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="13">
        <location>
            <begin position="286"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3224441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="520" mass="60075" checksum="759FBAC36DE6B544" modified="2024-05-29" version="1">MFVFGEVQEPLDETSQLVEDITRSQIIETIQRAVHICNKRGSKFLSSEDLLFLIRHDRSKVNRLRMFLSWKDVRKNSKGGGETKPEDMMEEEDAEKPKVKKMKIKFSWDMINSFSNVLSDDEDEEEDEEGREAYEDQVARLKVADEVTKTMSKEEYIYYSDCRQASFTYKKGKRFRDWCNFSSFYENKAKDEIMEILGFLGYEIVSQLTETGLLVKKEWAKIEQEQRKKNFVRDAGLEDKKYLFGKPASEQTPLLPIHIQEGFRRSQLINNPLQNFNGSFNISDKVLKLAVSEGCVNLEKDVVIEIGPGLGSLTRSAINLSPEGIYLIEKDPLLKNTLVELKSLSKDRIKKIFIDDALHFKQDALMKEILAMAPKKIHIIEMTFLFQSEIGEKLTAKPGTKFRGRLTNLFDTLCTVKDKFYLTSQCFVPVPKVDVAVLKIIPRKVPLIPEGVSKEFERVVTFSFLKKRKTITNSLKSKCRDIKSILKVVNIDGSLRPEELTTEEFIRLYTYLTANNIRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6B1</accession>
    <name>A0AAD5U6B1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPB4</name>
        <name evidence="5" type="ORF">HK099_008241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000089">
        <property type="protein sequence ID" value="KAJ3224560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6B1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030880">
        <property type="term" value="C:RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="4">
        <location>
            <begin position="20"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3224560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="146" mass="17084" checksum="E49810318C92FD2A" modified="2024-05-29" version="1">MMNRRKEVVEEDASKNLFSPEFTNVQCLLISEVRVLLQAKKENIKKEGGQKNVAEIIQKTIDYCDKFSKFQNKNTVKEVRQLFDPRDDEERRVDLHFNQFEVAQLANLCCETTEEAKILIPSLAEKDDDQLQNKLTEMQNLKKYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6S9</accession>
    <name>A0AAD5U6S9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein 135 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_004887</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM135 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000036">
        <property type="protein sequence ID" value="KAJ3226434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6S9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031926">
        <property type="entry name" value="TMEM135_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15982">
        <property type="entry name" value="TMEM135_C_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Transmembrane protein 135 N-terminal" evidence="6">
        <location>
            <begin position="380"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3226434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="547" mass="63186" checksum="B8CCCBB1AF4ED3EA" modified="2024-05-29" version="1">MVNFKLYENFIESIAVVLSKALTNDEREKIAKNFQSFNERLRQLSSDNLKRIKQEAEIKRPYCKHKLTCTQSCIRSFLKSFCTTYILKYALGFIPTLMTGKIFRNPRLILLLGGRDTTQLSLFLSSFTFLYKVLLCSLRRIFVSNDWKISFIAGLVASTSLAIDRNDTRRLMIALYLSTRNLHFISRHLWRIHVEPRWDPNDDSQNEVKEEKTKPKYLISSPRIPGEVRKYGEEINPFSFEFSSKIPKSLETKDSKKVETVVTTRKLDNKIDIIRKFVRKCAAVSLMMISSGQIAYGFVLHPETLNSSYFSFLLLHGNFKKKEPLRAKNYLNAWTNVITNIATNNLSPLYNEYKIPPELKEFKENLGMTKSGMLMCSLQHGNHYYCSGGALSIFKSEILRAVALYAPLNFFMTVVFKIDKFVKDPKNTLLIVTKSILRSTLFLASYVTVAFSSVCYFRRIFGGDKIWMYYVNGFLAGSTVLLEAPGRRLELALYCFPRALESFFNCGVKKGWFRNIKNGELIYFGLSMATMMTLYQHDPESIHDGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6W5</accession>
    <name>A0AAD5U6W5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Cytochrome b-c1 complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Complex III subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">HK099_004326</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The complex plays an important role in the uptake of multiple carbon sources present in different host niches.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Mitochondrion inner membrane</location>
            <topology evidence="1 17">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the UQCRQ/QCR8 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000030">
        <property type="protein sequence ID" value="KAJ3226716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6W5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.210">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004205">
        <property type="entry name" value="Cyt_bc1_su8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036642">
        <property type="entry name" value="Cyt_bc1_su8_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02939">
        <property type="entry name" value="UcrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81508">
        <property type="entry name" value="Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="12 17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10 17" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0519">Myristate</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 17" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 17" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="161"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU368118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAJ3226716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="275" mass="31969" checksum="1B40DA3AE77D73F8" modified="2024-05-29" version="1">MGGQMWGNQGSHQIGFYEYGISPFHLKPFKGFFNPGAFNFFKRNSRNLAYIAPPFLALSFAVDWADKKFEYYNRKEYLLSPEVSLQEIEKLRKEFKKRSKDGLSITKDQFRDVLKTQVQCWSAGAQFLFLDRLFDAFDLDNSKSIEFNEFIGGLGVFLKGTPEEKMELSFRLYDVDKSGSIEPNELIKIMGQLYSAFFNSDQTAHVKQMVNQIFNDLDINGDQSLVNILSKIYINYSLIKSISEYKLMALKEPIMIDILEQFLYVEQCDRRKSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U6Y9</accession>
    <name>A0AAD5U6Y9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U6Y9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="83" mass="9663" checksum="529DCBCB58E3C79C" modified="2024-05-29" version="1">MNQNSAKTQVWKQFWNSFESNIPNAQDFMEVDGISNNSDFNSVSYDMEIDSTSKSLSSNFSLNEIQLNLKNLELEKRQYARIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U713</accession>
    <name>A0AAD5U713_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_004083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000028">
        <property type="protein sequence ID" value="KAJ3226814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U713"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3226814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="728" mass="85399" checksum="A2E6FA01C05094C3" modified="2024-05-29" version="1">MKNLREDQSESGRPFKKSKVDAFEVLPHSKDCQIQNCSICVEADYDLEKLAMLPPRELLNFTKNFASTLKKKDEEEDETNFCIKLFELILKNLDAETPFKNDSVENEVVKGECYFEFGKFLNLEEYLQKSQEIYKKLNCESNNKFWIESCLCKLSLLDFERKERETKFTTFYDSEDVESDEEGVSLDNDDVPLINDDKYLKKNARIEYTNFFSQLNDGLEKCSKNLDKDFLKKLLLLVELNMNLSNSNTTKRSKFCLKNIKIKLLDFNIMALKFLDSLTEHVDEQLKIKVNKELGSNYYELGQGFLKLNETALSYKAFVDAVDVLNALTKRLTSRKSNVLEESSTFHLEKLGQTFIQLAAIEKDEDKILEWYESAVKCFTDASIINPEMKKRKFEKVEPVKNEFVCISKLNYIILNLNLNNIKESMRGLEFNHPDERLGRDDKRYYAAPVDPKNYLNYRDLIMHYQSSCFEAEALTLQEIDRQLKVHAKTNLNTTQKFKFAPKSYNFKSNKKLLSLTHSCIIDLKLEEGDINWENHGHRIYAIRRQSLAPLSNLNPLATSNLLILNLSRNSKITSNSIINLQRLKKLITVDLSETKITKSDFFKFFNEKQYKRFNCDIDNLKKLIMGFGPQRRNLFSELYLNDDILKSRHDLWYSIFGKMNYHIEKFEDPVEKFLDINYLPKPHNFEAFRVNCDNHYSFSNNENSNTTPKLHPTKIKSSKLTFLRFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U717</accession>
    <name>A0AAD5U717_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">26S proteasome complex subunit SEM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the DSS1/SEM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000030">
        <property type="protein sequence ID" value="KAJ3226718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U717"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007834">
        <property type="entry name" value="DSS1_SEM1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05160">
        <property type="entry name" value="DSS1_SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01385">
        <property type="entry name" value="DSS1_SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU369057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3226718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="86" mass="9945" checksum="AFD015854CE0B4F5" modified="2024-05-29" version="1">MVKEEKKVEEEKAEKKAQLNISDLDEDEFEDFPADEIPVEAEKKKEGFEHTVELDATWEDDVVEEDFSNRLKKENDATTGVAPMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U792</accession>
    <name>A0AAD5U792_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial aspartate-glutamate transporter AGC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Aspartate-glutamate carrier 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">AGC1_1</name>
        <name evidence="17" type="ORF">HK099_003347</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Calcium-dependent mitochondrial aspartate and glutamate carrier. Transport of glutamate in mitochondria is required for mitochondrial transamination reactions and ornithine synthesis. Plays also a role in malate-aspartate NADH shuttle, which is critical for growth on acetate and fatty acids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U792"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015183">
        <property type="term" value="F:L-aspartate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043490">
        <property type="term" value="P:malate-aspartate shuttle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000004">
        <property type="entry name" value="Calcium-binding mitochondrial carrier protein Aralar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="4 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 15" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5042237572" description="Mitochondrial aspartate-glutamate transporter AGC1" evidence="16">
        <location>
            <begin position="16"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="164"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="263"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="361"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00059916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00082232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3227128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="507" mass="56202" checksum="242064540BFFF841" modified="2024-05-29" version="1">MYFLFFLSLIKRLSAHKISEELEKTFNSTFPSNKVTFPIAEGIFKIVENLDNLKFSLEINVNPVEKEKLNTANFFKYCLKNKVFTSMELDLIFKLVGENSLLEELEEDEEEFTKSNKNSVMDVKKFEKIYLPSFGKQFETLKEKYEIKKVEAAKYQPTGIMQVAFSTYNFVLGSVAGALGASAVYPIDLVKTRMQNQRSSKFVGQILYKNSLDCFVKVFKNEGVKGFYSGLLPQLVGVAPEKAIKLTMNDLVRSKYKQKDGSIPLYAEILAGATAGGSQVVFTNPLEIVKIRLQVQGEAAKVGAAPKQSAMQIVRGLGLFGLYKGVGACLLRDVPFSAIYFPTYSHLKSSLFDEGKDGKKLAGWELLVAGAGAGVPAAYLVTPADVIKTRLQVAARSTETSYNGLTDCFTKILKEEGPKAFFKGGIARILRSSPQFGVTLFCYEKLHSLLPFNLIDPKFVDPSLATTSTSEGLVGSAVNAPFEKELDSYRRNSLRTTFDILPKIGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7L5</accession>
    <name>A0AAD5U7L5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TATA-binding protein-associated factor mot1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Modifier of transcription 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MOT1</name>
        <name evidence="14" type="ORF">HK099_005878</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000048">
        <property type="protein sequence ID" value="KAJ3225945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17999">
        <property type="entry name" value="DEXHc_Mot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000009">
        <property type="entry name" value="B-TFIID TATA-box-binding protein-associated factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000428">
        <property type="entry name" value="TATA-binding protein-associated factor 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044972">
        <property type="entry name" value="Mot1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044078">
        <property type="entry name" value="Mot1_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022707">
        <property type="entry name" value="Mot1_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498:SF1">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12054">
        <property type="entry name" value="DUF3535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="1371"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="1718"/>
            <end position="1878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="221"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00073046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAJ3225945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="3469" mass="395297" checksum="7258C74E4D363AAF" modified="2024-05-29" version="1">MTRLDRLVLLLETGSTSAVRLTAAKQLGEIQKQHPEELYSLISRVVTHLRSKNWETRVAAGQAIEAICANVTLWDPLTGTDKIDLEEYSDGLFNFESFDIESVVKNGAHLVASAGKEFDAGIADMDPKERIALQKKQLKQKLGLGTEFMDVDFFTEADISHSDEVINAQPIKKEAKMLLEESRQIVPKVEESNQALSARERNLLKRKKKLAAKGQKEKVQIMDISSSSTAKKRQSSYDDSAPSKTGMAVAVKKEKNMDEEDDLAPTESSLSDHLSNKVVVEHKPKEVQLFSGSYGSGDEWPFEGLAEQLCLDLFAPNWEVRHGAAIGLREVLKLQGSGAGKVVGPSKAENEMMHKKRLEDIAIRLLCVLALDRFADFVSDQVVVPVRETAAQTLGVLLKWCDEELCRKVMYNGLLKLIELDPKKGLKGDDSKARWEIRHAGLIGLKYWMAVRTDLVGEMIVSHVKGEETGVFKAIINGLSDSNDDVRAVSSSTLLPVTSILIDLLPTEKIFGSVVTTLWDCLQDLDDLTSATSSVMELLSQFLMQPAIVEVMTSSKIGLSLEVLAPRLFPFFRHAISSVRVAVLKMVETLVDVGMIMLQNKSFNGNWVGTELLRLVFQNFLLEENPDILKRTFSLWKKLISFLIRKNEKLPNTLSPLLIKDLPEKGGKSLIAVWFTLLMTPIGHKLDINLFYNHQSKGKFSKSSEEGLNVSVHDKAMAAQDLRYLLYNFLLFVKLLRIISQDDVIRGRITAATALGIILCSLSATELFYNSAAESIVFNFLQGHLGSSWASHRVFSSIIIDEWAGWYEEIHAIGSALPLVEKSTLIAKLCELMLSELIKADCGTTLLYEELIVYLYQVRQNVLILFNLFSEYGVNSLPPIPPFQGQNSVYTVGIFGPIFTVELAEYIVTEYFSQIIQTIPNQSSSIPTKTQPNPPDRHTLLYDKCRQIRYSIDAFNEAQQRCEARVLGCISAAVVKLGKIPGKLNPVIRSLMNCIKFEEHKDFQRRGAYGVSRLLELNIKTNKPVAVNEKIIKNLGMFLCSDPEIIGDVRQTRDSVGILTLRKMDDNYGKEVEASVSKNKRKDKIQALKKEELQVDKALLAEENETQKKSRILVRRGAELSFQMVFERFGSKAFELCPKLLNLISLSIQDYNLSDDLLQKVYEKVLSDEIYAQEVVDTLFTIGTVVPYIHHDLYPALVLMLKPLCTTLKTPLAVVRSSSSISIASMAKVVTLPTMQAIIENVLPLLGDTKSVIHRQGAAECVYHIIKLLEHNILPYIIFLIVPILGRMSDSDESVRFLSTHIFAQLIKLVPLESGVPDPVGIPQELVEQRKEERKFLGQLVGTEKVENFELCVEIKAELRPYQKEGVSWLAFLNRYGLHGILCDDMGLGKTLQSICMLASDHNIRAEKFAKTQSPDSCPTPSLVVCPPTLVQHWFHEIANYAGFMKAIIYAGNPGERQRIRKQLLNFDVVITSYEVLRNDVDEIAKNDWNYCILDEGHIIKNTKTKLTKAVKTVKAMKRIILSGTPIQNSVLELWSLFDFLMPGFLGTERQFNERFGKPILNSRDAKSSSKEQEQGALALEALHRQVLPFVLRRMKEDVLHDLPPKIIQDYECELSDLQKMLYEEFGHSQARDGVEDAFFGEEEEPKKKKGGQHVFQALNYLKKLCNHPSLVLTPEHPQYEKVIAKVKADKSNLTDLRYSPKLMALQQLLQDCSIGSDSTSDVATVSPHRALIFCQMKQTMDLIEHNLFKNLMPNVTFMRMDGSVEGSKRHDIVTKFNADPSIDVLLLTTSVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRIGQKKVVNVYRLITRGTLEEKIMGLQKFKLNIASAVINQENSGLKSMDTEQILDLFSLGPGQEDSKKKKMKEKGKQTTKDIIDSLDGLWDESQKNKKMDRSSELGRQFAESLMLSQIDDDEIFQLIDIQSRRSANFSLFYSSFLSSFTERLTINLGAIETLQQTLTLILKLLKLYISHVNSSFNQNNTTSLTLYCSFLSEIVALTFRSLPFFVLDGIENANCEVYYNSYLEWLEFLKTCYIPYMTLTSKLEYDAKLKINTQQIIAVFAMANYVSRYGLMLDFKGNTKSFDPLEKFLLHAICSFESITSLNPLGVISKHFVCIFKENLVTDKIRISSLENLHKFFIGSLVSCTQPYAEEGLLISAETVEEWRRLCIHSKPSEFSQIAETHNLAQFSRDFLVFDYVFTQNTYFEVNKYSDAYYLTKTSNLGINKNFLMFSKQFLSASHHPDFHYRLLKEAGEQLVLPDINVSSLKTRGLILQRCIIIQEAFGGFQYPLCCHCNNSKDTELLFKWKILMQVSNDICGKKYVRTNLFDIFFADLHHLLVKIKSSSARIEKLMSTVKHFLIQALEECPSKHYDILTSISESNWAALKSQRLNYSNEGFYLLPLIYSVLSEYRSANAQEISELPWQLFFVKSEVPEVFVNILLDLQKKDKAEGSLRRTLLFLNMLEHELKHEVGNNYLSAVSKFFDILRKTANDTTNIRSCEIVTPYLEIKSLLIQNSQRLYELAKLFMATSAESMEQNTAIEEGEFTTADDIDRCSHTFSKSLNDPLFTLERTDKNLEEGSEFSGNASNPLLLNNTILEPEFEAKNDFFAMINEMALKWSEFVCQYSYSYFNKLLEKIIDLVIVTEPPRLLEHVLLEFIKINPVFIETVFSTIIKKFGETKFKYNEEKCIFKPLIYMFKNDVDNSSGINFKTQILKTITIAMAHIRTSRKTIIKFLYDLLKFSKYLRESYFCWVLNQMDLQVPPSNQNNLDLNFLIKELVLNDKSEENLIIETFIPLYLTEDINSTKNLFFFSKRLFKRWEKGFGFNRLIRNYFSAVHISRNFVTEILEISLRASIIEEGEDVDDTIFKSFSESLYREEDEGGYQILLGLETVLLITLDEADNSESLKKMSLPSMKHKKSQSSSPMNISKKKELNWFFEYWIKQIVETIVGSKTPTQTVAYHLLKFLSSHKTLFPKLFMQEYQGVSGLSEIFKILTNFEEEQNANLVVKAILDGVITALHNTVETFENYLSWVFCVIPLYQDSSIEIKQEILENFICEGIMQKLYEDHGTSSNLTQLYVQKFFEGMINIVFTQMNSTDFIEIFVSILKAIIRSGMEDEDNNFQKFLKRNKFLGEIKKTFEDFFFNVCVNLMETDDNDRNNHKSSSDFLEVCCKGLELLWNLANSSIMMQSIKQSLITDNIEPLVFKTSEYIVFSSLPIMDSLFTILNSVDYKNIKERCLQILTKIFQGKIDCENTDALSASNNYFKELSLLECNIKLLVKLLQHPKLSIKCYDFIMVVLLYEAGEKFKLTFSSFGRGLLFSTLTQLIQNLNCTEEMEEGESFVEEIGLECKLILRLMEIDSKFGLERSIETTNEFSFAIISQLLILLDAQKANNNTLSSKLHSTIYLLAKNAFEFIKSSPNQHILFDKRFLTPDYEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7P4</accession>
    <name>A0AAD5U7P4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP4R2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000116">
        <property type="protein sequence ID" value="KAJ3223815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7P4"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015267">
        <property type="entry name" value="PPP4R2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487">
        <property type="entry name" value="PPP4R2-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16487:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09184">
        <property type="entry name" value="PPP4R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3223815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="193" mass="22458" checksum="1909701E336D3EDE" modified="2024-05-29" version="1">MNNIPINTDKSDEIIHCAKTGRMDLNWEEFKTLLQKKLYFTFNTYKNLQDDSGLNEDKSNSFQQQREIGKDSESEPPNVFGSGKNNNDNKKLTKFPFDSKIEYLSDCLNIFQKNPPFTLQRICEILLDDQRLYKNVWSYYRALEKNLSVTDELTSTVCSEETSFLLHSANNTSEALKKKRLISSIEEDLMDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U7Q0</accession>
    <name>A0AAD5U7Q0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">WD repeat-containing protein 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">WDR19_2</name>
        <name evidence="12" type="ORF">HK099_001930</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U7Q0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056168">
        <property type="entry name" value="TPR_IF140/IFT172/WDR19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040379">
        <property type="entry name" value="WDR19/dyf-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039468">
        <property type="entry name" value="WDR19_WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056170">
        <property type="entry name" value="Znf_IFT121-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920">
        <property type="entry name" value="OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14920:SF0">
        <property type="entry name" value="WD REPEAT DOMAIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15911">
        <property type="entry name" value="Beta-prop_WDR19_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24762">
        <property type="entry name" value="TPR_IF140-IFT172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23145">
        <property type="entry name" value="Zf_2nd_IFT121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDR19 WD40 repeat" evidence="9">
        <location>
            <begin position="24"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="IF140/IFT172/WDR19 TPR" evidence="11">
        <location>
            <begin position="630"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="IFT121-like zinc finger" evidence="10">
        <location>
            <begin position="998"/>
            <end position="1044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF15911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF24762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3227474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1124" mass="126846" checksum="5EF8C1E85BBBE560" modified="2024-05-29" version="1">MTISDQALVDQKISSIVATSPDLIKRSVEIEPTIVGLGPTHFVIGLDNNAWFYSIRGPKKDKPLVKRQSAVSRLLPSTSDFNSLAFKKSFVANIVSISLNAQFSSVLLADGKLYLNSIEEQEQNTIEKSKQFQKVFPEKDILLKIKPGKDFKVTCVELTNEFLIYGTSNGLIHHYVLKEWVLVNEIKHKYGIRNLAVNEKGVKFTFIDDKNEAYLCNPASNTMLRIVGGLPNSSGMIWNKIINSPAQNQSHRNIFVSWNNNSINTFSYQPFTTRGAECVLLGATRLPHGMIPITAINGVLTCLTASGKLSLVPLISNEEIKESNRTGTMLYVPKLSSEVETKNEIEQGRILQLYYSLGQMKEIWNLIPIIKTTKPWLTLVEQALHVLDILTAKRIYRQILGNVGMVLTLEDLEWIDDRNLIAGHVSSILGNISLAQDFFLKSSNPIAILELRRDLMHWEQALNLAQTLAPQEVTIIAKEYAHQLEFDGIIFFSQLLSTFFKLAKYSEAFAMYEKALSTSSTHTGHEDQLIDHQIACSGGLTRMTCRMGDIARGMKMLNGCTDKQLLSECGSILESLKQYPESGSLFERAEKWERAAESYIKAKNWTKVGSLIPLINNSKIIVQYGKNREAEKLYQDAALAYEKGRDYFSLVRIYVDHLKNIDAAVAIVRKTQCRKSAKLVSKFFQSIKDYKSVIEFYVMAGIIDEAFEIATQNDVVEHFAEIIKDETSTEMLLNISNYFENKKQFFLAGKYLLQCGQYSKALHMLLQCPTENSAAIDLAIETVGLANNDGLTHELIDFLMGERDGVAKEAKYIFRLHMSLKQYKEAARTAIIIAREEQMLGNYRAAHDLLLDNYCQLRNMKAKVPSELAKMLMLLHSYILVKVLIRLDDHEKGAQMLIRVSNSISKFPSHIVPILTSTVIECQRAGLKRHALDFAAMLMRPEYRNKVDAKYKKKIEQIVRRPDKDQVVESENKSPCPFCNSNIPDSLLDCPECKNQLPYCIATGRHMLFDDWTQCPHCEFPALYSHLKVVVQKNQQCPMCSKSLKLEQLVFVKDPTEHLRGKKEEKDLEEKGLEETGGFVKNTGNLEVKVMKGISKQNDIGGNSGIQIAPAATANMNCATYINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U844</accession>
    <name>A0AAD5U844_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Presequence protease, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Pitrilysin metalloproteinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CYM1</name>
        <name evidence="17" type="ORF">HK099_006052</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running. Preferentially cleaves the N-terminal side of paired basic amino acid residues. Also degrades other unstructured peptides. May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer and homodimer; homodimerization is induced by binding of the substrate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M16 family. PreP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000005">
        <property type="protein sequence ID" value="KAJ3228172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U844"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000013">
        <property type="entry name" value="Mitochondrial presequence protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000009">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000011">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 17" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16C associated" evidence="16">
        <location>
            <begin position="472"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3228172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="976" mass="110511" checksum="FC2E8AC164369D42" modified="2024-05-29" version="1">MLCTSSAILKGNSSIVHGFKVINVKQIQDLEISAILLKHEKTNAEYLHLAKNDSDNVFMVAFPTPSFNSTGIAHILEHTTLCGSKKFPVRDPFIKMYNRSLSTYMNAMTAQDFTFYPFSTENRIDYYNLMSVYLDSVFFPNLNELDFKQEGWRLENEVTEDPNSPLIFKGVVFNEMKGAMSDPGNLMWTRLNEHLYPDSAFGQNSGGEPINIVDLTHKQLVDFHKKNYHPSNSKFFTYGNFSLEEHLKRVDSVLSQFNARKAEKSTEVQLLKDSKIVTLDYPADPLNYTEKQHKLSLTFQCNETVDYEEALAVKILSSLLLDGPSSPMYQAFISSNIASEYSATTGVDDSTNIATLTIGFQGIRKDDIEMIKEKIFETLRVAAGTGFTDHHISSVIHQLELSLKHRRVNFGLSLGQSVIGNWMHGGNPLIAINFSENLNILKEKLNRDKDFFNKLIKKYFLAVNKKHFTLIMQPSDQYIHILQEKEKAKLSDILSTLHVADKKKFFEDGLKLKELQEKKEDLSSLPTLTLQDVSSEQRAFDVLHIQQPTSIQLRETGTNGVSYIKVQKTLDLPALYYDYLPLFCSAFTLLGTNKNTPAELSDKLNLFTGGVSATVSTINLAASPLPAFSLSSSCLDMNFDNMKAILIELMTEVNFENLESLRSVISQCANSLRDSVPQSGHIYSIACSSSDFSWNLALHQKLHGMEQVFFMNRLLERINGKEGEQALIDVSFKLKEILNFILSNGNSRGSLITQNLSNIKPKFQNFFEDLNWTNEQKIYSKKEIALKYEKLLLTNKKKLEVENKIVLPSLQVSFASKSFKTCSYEHEDSAKLQVLGSILGNKYLHREIREKGGAYGGGAQYNALSEVFSFYSYRDPSPRITLKIFDDCVNWGAKLTQHVGEQELSEAKLLIFKVLDMPLSASEEGSALFEKGLTDEMRFEKRRQLMNVTLRDCEEVCLKYLKNNALNKAVMIGGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5U9R0</accession>
    <name>A0AAD5U9R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_004591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000033">
        <property type="protein sequence ID" value="KAJ3226564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5U9R0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929">
        <property type="entry name" value="ALPHA- 1,3 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929:SF220">
        <property type="entry name" value="FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3226564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="428" mass="50805" checksum="5FB29B83ACC57382" modified="2024-05-29" version="1">MYKPTEQNVNDHSQVPETMINFSNDNYGFYQNSHQRKASPNLDSNKFNNQEDEYKIYQKNKGTRDNSILIGVNSQIYNYENKFNHPWQLLYFTRRCRVQCNYVALDKKFGKYFTQNKKEHQWLTKEQGENLMQRADAFLISSENYTAKHTEKYLAVIEKRLPNYEYNHKNLDDLTATSDDLQYDGLKFEEDFTVENSNENVIWINENQFASNITFNFITNTYRDLGDFRERLDLMNLKLKNFNKTNSVIAFLPKCSNLHESHLKYIKVLSSLVEIYFYSGCFSIEIPEPLKLNDEKKMLLVSKYKFVLQWDTRYDFGVVSEQFFQYLTYDTVIIFFGALNIKEFLPKKGTIIEVRRYEDPNELGNLVKDLMFNDIPSYEKMLNWKRFDALTNNAGNLKIESQFQNLFSNSVESVVCRLCENVKLLKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UB37</accession>
    <name>A0AAD5UB37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000009">
        <property type="protein sequence ID" value="KAJ3227904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UB37"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="63" mass="7268" checksum="FF484871E74DC1F5" modified="2024-05-29" version="1">MVDLDESVAETIKLEKEMKEKKKEEKKRKKMEKLKKMEEENASFIDKDVSAMMGFGGFGGSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5UBW6</accession>
    <name>A0AAD5UBW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000008">
        <property type="protein sequence ID" value="KAJ3227970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5UBW6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3227970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="201" mass="22650" checksum="DE85F1B1A0C2B522" modified="2024-05-29" version="1">MSAGKTQNEDNFSTSSTESKAYSMMAPFSANCKESFANISPDSIANYESEFLRIEYYCNVIMIFETLACVGNYLPETNASRQNISKKLEISKMKFKFLVLTNILVIVDLSLVLFYLLGTFLYKHISNELTHIVNHLSVIHVFTSFILLNLYSNGLKKAKKIIKGTKQIEVTQLSHVSLQVNEAETDAHFAASNLHNETESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRP0</accession>
    <name>A0AAD5XRP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_003393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002223">
        <property type="protein sequence ID" value="KAJ3198948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRP0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3198948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="114" mass="12285" checksum="17F97325981F06BB" modified="2024-05-29" version="1" fragment="single">FVYGFGEGISDFFNKPVKGGKEDGVYGFTRGFAIGTTSLITKPLGGTCDLIYQSGLGSYKTAKKLMKKKSETLKKSSSQGSLLNTLSDDEAADILIAFDDHLNNNFLFVKAVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XRZ6</accession>
    <name>A0AAD5XRZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Guanine nucleotide-binding protein G(K) subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GNAI3</name>
        <name evidence="7" type="ORF">HK099_002509</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001832">
        <property type="protein sequence ID" value="KAJ3200808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XRZ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3200808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="234" mass="26425" checksum="D83183064051F65F" modified="2024-05-29" version="1">MEENKINLDENSSKLSIQMKEIEVKNSDTKSEISKAISSSSRGSVNSGISSSSKSTRLSVNFGELLDTEEVGVNFVRDLLLSPRKAITRNRMIDKQLKLDERQFKEEAQKTARILVLGSGDSGKSTFIRQMRLLNEDSFNQTEIDNFHNTIIDNLISSLKNLILGTEKLGINTTTEDYINDVQHLLDYEWLSTDYLVSPITAATIKRIWSDKNLKLCFSRKSELKGILIQDTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XS73</accession>
    <name>A0AAD5XS73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_001191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001310">
        <property type="protein sequence ID" value="KAJ3204355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XS73"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF110">
        <property type="entry name" value="2-PHOSPHOXYLOSE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3204355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="516" mass="59138" checksum="23662DBD80E4AE19" modified="2024-05-29" version="1">MVFIEENVEIKNIHYDGMIVLDFKKQAMSINLGGELEPYHYPFRGVAQRSVLIAQNVKKYLVIKPYNLLNMPFPFFDNESVSRLYPANLQLKKLILFHRHGERTPVDAERKPWKMCFLSPQLHNFYVAAEKFTGKDHSPESPASEGSSTKYSNSNISNLLNFSGVIFEGNDSKVKNLKALNFFDNFADNGSCLTGQLTDIGKLSMQKLGGNLRNLYVDQLHFIRGELDDKTKNNVYVRSTDYARTIESVQYLLNGFFPNQYRVEKNWSLPIHIKSEETETLYPSDASKIAVDLSKAFKVRVRKELQPAIDDIVLRMKKIGINVAPRMNKLHHLNDYFLCMKGNGVQLPPDVTDSDLEDLERICVKDWWEKYQVDPLLCKYSISGLMKDLKSDLLETDRKSKVSIYSGHDSTLGPLLSAFQAFDSKIPPFSSIINIEVFEEKKTMFNFFKNNAYVRLLYNGKVVKIPHCQDNSRNLNGDGSFCKINSFLEAVEKMIPSKQDEENDAKVVDVEQVNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSN0</accession>
    <name>A0AAD5XSN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Reelin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001206">
        <property type="protein sequence ID" value="KAJ3205411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSN0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4060">
        <property type="entry name" value="Reeler domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002861">
        <property type="entry name" value="Reeler_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042307">
        <property type="entry name" value="Reeler_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02014">
        <property type="entry name" value="Reeler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reelin" evidence="2">
        <location>
            <begin position="137"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3205411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="431" mass="46877" checksum="73B6DC1C54800CBA" modified="2024-05-29" version="1">MVLCPSGWNYLLENASEVSTNDMIDTPKTLLAHKITSLLDIIMNDSEAFVRRSALLSLISLIENQDFLISEKKSNQIFLPEDSDLWRKRMYLQKILISLVLLKMMTSKPGAAPLCDTFEAGKKISASPMGENSKPLNDIFKFLADKTTYKPGEKINFKLSGDAEFVGFLMYVTGSKANTEARVGKFETNEEFQNNEAACSSQKLDDKDSVITHKQGKKYAPDSNFNFIAPSADVGDLTLHAIIMQKNGDKFGWGVFENAALIKSEGGNEAEPAPQVNAEENQSPVQGNQGEVPIKGVEVVNESECKPATITEPAQTITQPAVTVTNYVTAVPLTKIQKCKPKNWGVIPTNGAEIINKGLNIPAVGAVNGGYGSGEESTDADAGEKGSKAAGEKGSGDEESKPAEKLETIEEEEKKAETTQETKKEEHNHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XSP8</accession>
    <name>A0AAD5XSP8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP-dependent DNA helicase II subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">ATP-dependent DNA helicase II subunit Ku80</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">XRCC5</name>
        <name evidence="17" type="ORF">HK099_000496</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ku80 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001112">
        <property type="protein sequence ID" value="KAJ3206608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XSP8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043564">
        <property type="term" value="C:Ku70:Ku80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00873">
        <property type="entry name" value="KU80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="DNA_bd_Ku70/Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024193">
        <property type="entry name" value="Ku80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604">
        <property type="entry name" value="KU AUTOANTIGEN DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12604:SF4">
        <property type="entry name" value="X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Ku" evidence="16">
        <location>
            <begin position="275"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAJ3206608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="602" mass="68348" checksum="6DD2A2D69F9AD3EC" modified="2024-05-29" version="1" fragment="single">MSKFATTFILDVGNSMQREDSMDKTTYLEKATTVLKSILDSKIIQGRKTDVVELIFAGTDETDNPLAEDGQYENLNLKFSFTQANIKMIKYLDSLKKKPNNGNVDIMDALILALFSMNNFCKKLKYEKRIYILTDCQNDMLLDDFTTVKDQILSMNVSIDRKNEEILKEITEFSNGLIFLDREAISALSQLRTKSVKPTTLLRAPLTFGDPESHPEETLSISVYTYLKTSELSAKSAKKWSSIAENTEPESRTCKVDTVRTLKVTKTNEDGMDEDITVEKEDLIKAYRFGKTLVRYTADDEEAMKFRCSKGLSILGFVKKQKIKRWWLISNTISVIPEPGNSYAHVQFASLYKALFETEYCAMVRFCAREDSALKIGCLVPHEGKPYLLFCQLPYAEDLRPYEFTNLKSLLDPENIKVEDPNSSSSLKPKRNKLEARTVKASEAIQRMENFILSMDLMHAIKNPKGETKEAYKTKDIFNPYIQRVNQCISHRATNQIDSFHPTPLPLCDPKFLASITPIPSLIESSRSCATALKEAFTLLKQETTKKTGKRQWQSNKDILPGENVDAIAADRILQNMGNEDGPDAKRRKGVDGLLEINSLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XTZ0</accession>
    <name>A0AAD5XTZ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphotransferase</fullName>
            <ecNumber evidence="11">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">HXK1_2</name>
        <name evidence="15" type="ORF">HK099_006952</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16126"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22740"/>
            <dbReference type="ChEBI" id="CHEBI:4194"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:229467"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:22741"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="11"/>
    <dbReference type="EMBL" id="JADGJW010000636">
        <property type="protein sequence ID" value="KAJ3214272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XTZ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24018">
        <property type="entry name" value="ASKHA_NBD_HK_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.367.20:FF:000020">
        <property type="entry name" value="Hexokinase-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000034">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF16">
        <property type="entry name" value="HEXOKINASE TYPE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase N-terminal" evidence="13">
        <location>
            <begin position="63"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="14">
        <location>
            <begin position="267"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3214272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="507" mass="55594" checksum="A04ABB9DF7C19397" modified="2024-05-29" version="1">MSSELITSSSPLLLSNALTFLFGLTAGVTIYSLLKTAQEFKTPPQSKLIPQNSSTQQTEYIKKRIEADFTISRETLLRVTKQMLIEMKRGLQSDGQTLKMIPSFVTNLPTGTEVGSYLALDLGGSNFRVCEILLSSDGSRVRSRQKKFVISEDLKQGTAEKLFDFFAEAVGIFLKEVLGESTDEFNAEHKKLGFTFSFPVQQTALNKGNLMVWTKGFTVSGVVGKDVVGLLQEAFKRKNLKITATALVNDTVGTLVSHAYTDPQTNAGVILGTGTNAAYVELVKNIPKWTGGPVTSGKMVINTEWGAFDEEHTVIPFTKFDKKLDRASNNPGKQTFEKMISGLYLGEIARYAIVDLMKTGYIFKKESLSESLLSKPYGFETAYMSRIERDHSKDLSDINALLGDIFKIFNSSLEERSLVKRVCELVGLRAARLSAAGIAALVTKMNKLDGCTIAIDGSVFEHYPHFGNRMRDALFELLGISAENIDFAQARDGSGQGAALIAALAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUG8</accession>
    <name>A0AAD5XUG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CWF21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006221</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000522">
        <property type="protein sequence ID" value="KAJ3215757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUG8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21373">
        <property type="entry name" value="cwf21_SRRM2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08312">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01115">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="11"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="108"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="108"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3215757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="292" mass="35200" checksum="53790CBA4FBB3FFE" modified="2024-05-29" version="1">MQDKIPNKELLEHERKREIEIKLLQIEDDLRDQNKDEDYILDHISKTREALLKKLTRDETFGLKDSKTVGKGETQRNYLLNKEKNTKFEKAFNINKDQFVEGASFDRELQERKKQERIAERERKQTEYEEKMKEEEKKQLKYEEERKKRVEKRKKEEKEAEELRLKKLKDMDEKKKNRTPSPQRSRRRENDYSPRSRRRNRDNSPSVSPRKRTTSSSNEKKRYDSDSRSKKDTSPDNFKRRREHSPQSPRRRRRSYSPRKYSEASELSQHKVRSKSPSPRSSSSSSSSSNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XUW6</accession>
    <name>A0AAD5XUW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001750</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001525">
        <property type="protein sequence ID" value="KAJ3202758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XUW6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014472">
        <property type="entry name" value="CHOPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414:SF77">
        <property type="entry name" value="CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414">
        <property type="entry name" value="ETHANOLAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3202758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="205" mass="23344" checksum="0442CC5685784DAD" modified="2024-05-29" version="1">MVDYTLSKKALDNLKLYKYASIDKSFISNHILRHYWNACTELFPLWIAPNLITLIGFSFVILSFLLSLIFTPNYDYKDPSWLFYFYAFSLWTYSTFDNVDGKQARRTGSSSPLGELFDHGCDALNCCFGAMVQASGLGLGYSWYSVSLLFITFTPFFFSTWETYHTGALYLGYINGPTEGLIMACVMLSMSGYFGKDLFFVSNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVB1</accession>
    <name>A0AAD5XVB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_000832</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001207">
        <property type="protein sequence ID" value="KAJ3205405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVB1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058669">
        <property type="entry name" value="TPR_IPO7/11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF18">
        <property type="entry name" value="D-IMPORTIN 7_RANBP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25758">
        <property type="entry name" value="TPR_IPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exportin-2 central" evidence="4">
        <location>
            <begin position="322"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Importin-7/11-like TPR repeats" evidence="5">
        <location>
            <begin position="607"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3205405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1018" mass="116348" checksum="05D6BC301F6F5FF4" modified="2024-05-29" version="1" fragment="single">SNHPNQAIRSEAEELLKNAEKEDGFLTLLMQLVGMPETDPAIKTARWESLDKSKTLVGPQDRAFIKANILNAIVHVDAKLRILFAACLNNILATEYPQDWPEFLPTVKTIIQSDDTNVVHAGLSILWEVISLYRFKAAEKRAPLHHIVSETFSTLLLISQKLLPRSEPQAGAMMHKILKTYYASIEYELSFIQQNSDSLIPWGNLFIQMIEKEIPVDLTPSDIAEREKFSWWKAKKWAYHSIYHLFVKYCVQPQSTKKSVYTEFSKNFITNFVPTIVQCYLKQVKLLIAGTWMSNRTKQQLSLLLTDCIKQKNTWLMIKPDLEPIVVSYIFPQLCVTDVDLEEWENDPVEYIQRKLDPMEDCRSSVAAAQGLLSSLVKYHFKQTFMSIINFVNGILQSYNSTPIEQRNPKQKDGAIHLVSCLARDILGKKSPIKDQIESFLATNVLPELRSSHPYLRVRACDVLIKFETAMVSREGDLIKGRENVQFIFDSLLACLQDSDLPVRVWGALTLRDFLQYESIREGLKPHVPGIMQVLLNLTNEIDMDTLSQTMESIAATYPEQLAPFAVQLGGQLRDSYLRIVGDINIDDDTDEALDEQADKTMAAIGIMKTISTLVISLDSSPQILQELELAVGPVVYTTLQNGILDLYDDAFEIIDAFTFCMKSVSPTMWSFFPLIHKAFKTDAFDYLEEMLPSLDNYLSFGKNVIIHNKEYQMMAFDIAQSTFKYKDAGEADYIRACQLFESMLLNLQGYIDEFIPQILETALQHLNNIADFKTTSFKVHCLEVVINSLYYSPLMTLSYLEQKGVTLVIFQTWFKELESFKRVHDKKLSILTICKIISYKYENLPQSIQSIWGMILDGALRLFSDYPAAVETRKKTAKMYEGGDSEGDYEEEIYEEEYENEDDEEDNGVGEDEKYVEFLHNAAEAAKIKEEEEQDNYESDDEWGVVGLEEDPFFVSVLDQIDPYIAFQDTLSAISAEMQHSLVQGLNEQQKILLNEVMMEANKIRSNPNPTESIIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVH0</accession>
    <name>A0AAD5XVH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004657</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000335">
        <property type="protein sequence ID" value="KAJ3219580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVH0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004493">
        <property type="term" value="F:methylmalonyl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046491">
        <property type="term" value="P:L-methylmalonyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051785">
        <property type="entry name" value="MMCE/EMCE_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048:SF3">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13669">
        <property type="entry name" value="Glyoxalase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3219580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="59" mass="6592" checksum="79B584219A8CB76C" modified="2024-05-29" version="1">MHHVCLEVDDINSALNDLKENKIRPLDPKPKIGAHGLPVVFLHPKDCGGVLVELEERKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVK0</accession>
    <name>A0AAD5XVK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_002399</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001791">
        <property type="protein sequence ID" value="KAJ3201045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVK0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052116">
        <property type="entry name" value="Centro_Cilium_Assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23170:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23170">
        <property type="entry name" value="NY-REN-58 ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="265"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3201045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="441" mass="50924" checksum="26AF8D9926F1332D" modified="2024-05-29" version="1" fragment="single">MFIETFTKKCEEMQIDIPLSIIDTLNKSSNSKTLNLSSHTLNQKICLALGFALKDDTQFEKLVIGDSFLGDDGVLPFANNLKHNSKIYFLDLRGNNIRSDGAIAISSMLKLNNSVKILSLEWNCIGIWETGVKSIADSLKNNHSLEELDFRNNKIGPQAAQSLANALKHNTNLKRLDLRWNNVGLIGGRAFLDMLKWNTTLSELELTGNEIPEDIIKSISLSVERNRDKQKTEMENKIHTSHLNSTLKALQTSHNETLSNFSLKYHESENTRSNLSIQLEKAIREIKEVNEIRRDFELRLDQVTREKNNLFETLEAERLNNSVKFDKIQKDLLSVREERLKREDQLGKQLSSVNFKLLETESNLRSLEVENEVLKRDKKLLLGDIDKFKEKEIVLNESWEEKVLKLELNFNNKLDSLKKFKDHELDEKVKRFEEKLKNADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVL8</accession>
    <name>A0AAD5XVL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen [starch] synthase</fullName>
            <ecNumber evidence="7">2.4.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GSY1_2</name>
        <name evidence="9" type="ORF">HK099_004450</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18549"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.11"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:18550"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.11" evidence="7"/>
    <dbReference type="EMBL" id="JADGJW010000313">
        <property type="protein sequence ID" value="KAJ3220144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVL8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000014">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008631">
        <property type="entry name" value="Glycogen_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176:SF3">
        <property type="entry name" value="GLYCOGEN [STARCH] SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176">
        <property type="entry name" value="GLYCOGEN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05693">
        <property type="entry name" value="Glycogen_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="467"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="483"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="516"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3220144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="566" mass="64672" checksum="AA279B0946918B79" modified="2024-05-29" version="1" fragment="single">SKTLESNPQHLQPAIIAHFHEWLAGVALVLIRKRSLNISTVFTTHATLLGRYLCAGDVDFYNNLKHFDVDHEAGKRGIYHRYCIERAAAHCADVFTTVSHITAYEAEWLLKRKPDGILPNGLSVVKFSALHEFQNLHAKSKEKIHEFVRGHFYGHSDFDLDNTIYFFTAGRYEFRNKGVDMFIEALARLNARLKSSGSSVTVVAFIIMPARTLSYSVEALKGQAVMKQLRDTVTEIQNSIGARIFEIAATGKLPTQEDIMHDEEQVLLKRRIFALKRDALPPIVTHNMQDDSHDPILNQIRQVQLFNRHEDKVKVVFHPEFLNANNPLLSMDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITSNLAGFGCFMDEMISHPQDYGIYIVDRRLKSVEESVNQLTDQMLEFCLKSRRQRINQRNRTERLSDLLDWKRMGLEYIKARWVAVRRKWPELIHQLDGEDSENENDIEGGFTGYETDRESNRGDDLDQLGYHVKVPRPASAPGSPKIRGIDDLDLMFRDDEEDTGKPKRRDSTVINGLKAMSLKGADPDYVPPVTSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVP7</accession>
    <name>A0AAD5XVP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_004358</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000303">
        <property type="protein sequence ID" value="KAJ3220435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVP7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032467">
        <property type="term" value="P:positive regulation of cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026708">
        <property type="entry name" value="CSPP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21616:SF2">
        <property type="entry name" value="CENTROSOME AND SPINDLE POLE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21616">
        <property type="entry name" value="CENTROSOME SPINDLE POLE ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="569"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="282"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="486"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="670"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3220435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1036" mass="121105" checksum="AA5BF39BFC90179A" modified="2024-05-29" version="1">MQVSHKVIPPFGTSADLPRPNDRSNVLKLELKNEMQNFLLSQAEQNPRLRRLQQKQKEDSNLGSQNVFGNRISDNNHSKQQPNLHTSNNNSNRSLPQQQQYQYPEERPNFSSAPNFGKFPQEHQSYNHHTRSSYNNSPINRDRYHYDDSSRYPPPRHNYENSYLDQNYMGERRRSENDNYRNIYNGDGRPNDPYAPRPMENYYHGPPSPTHYVSPPRMNYPENNPGFLPPSSRDYRNDYNQVPNTTQDENHTSRNTNNCNVNDATNATGWGPSSNRSVLDQANKKQEYLRQLDEQVRQKQNQKQREMASQQKVEIMNMNQEIASPWGKVLIEKTGRRMYNQQQQQPPVPQPYKEMKNPTYQQYIESLTANHPPNINNQSPPRSNFLEQLQSMAAVKDDVSLNYPASFEAPFNLNSSSPVSNAFGQTLAIQQFPQQNNHSATSSHLNNPPSQQISYSRGQANFENLSSWQRDEVLQKQKQIAETQFILKQQIAEKEAEKARQEAQRKLEEEREQLKLLKDQELLKERYKRELEEAKKAEEEARIENEKAIQLKKEKERLMEEKYNQAQNETILDKQKKRRGGNKVLDIEVGNENHKMGEEFIFRSNSPPVPTLQKKNKEEVKNNEEIYRSNSPPIPTVKKKLEEEANVKRSKTPEENHFRSNSPPIPALRNKGEKKKEAENPVEEKRNREESVKINQKKKELKVEKPKEDQSAVLQQLLNIQKELLCESEKVQTELKKPISPKAFEKKKKIEDLNKKSFKFIQNDEINTKKKFDQEEKEEEFKVNYSSRKKQKEYSFFPELDGEELNENDNNKLFKVDKKSLNELLPKTDFPPNPSPIPQESTKSSVLERQRILLMQQEKELEELRSKGEDLFISEKNDANFKKNKNKKNLKEEVLLNDFVENFKFQVDEKFPYSINQLRKDVEEEALISESKLIFSRKNDEFNFDDVEFLSRPSTVGNKTKTNLLHSLRPRTFDSVLLNNSNTMNFVDSLKSEESEFKSRPGSRSSLFKEKNLKLESDSSLKDLGIGRGGIDLFPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVU7</accession>
    <name>A0AAD5XVU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Low temperature requirement A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000931">
        <property type="protein sequence ID" value="KAJ3209614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVU7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840">
        <property type="entry name" value="BLL5714 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36840:SF1">
        <property type="entry name" value="BLL5714 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="460"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="498"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3209614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="557" mass="63481" checksum="AB0A01C705E33396" modified="2024-05-29" version="1">MSEIAKEIKDEEIAMEVDIDQLDEGSHENMDLMGVGGCNNFAPSQQNIVEELVMSDSITQKNASTIGEVYHESVDEFGELTDTEIRYIDTSEMEKLDRELRHTWFTNIHVRQYFHGNILYRERHMRKVTWDELFIDLLYVALFNRAGHIIGHHPDMNGLTEYLLVIYPIINSWTLLTYQSNRYGVNFYFKVYSWFAVVLAAVMGVNCENIANSDPHENTSHPFIISFLIARFLYLLYGGLGANHQRKSYVLLSFMNFVASIPWIISLFVDAKYRNILWFTSMALDYFGSPLTILAYKVSSLKNFVNLEYSMALNIEHFVERNGLFVIVALGEVVIAFLFESRGAHVSKTFLATMMGILISFSLNWIYFNIDGTSFKIHAFRRGKFYGVIWNMMHTPLIGTIILFGANMAVIVEKYSNHQSLVVKNVGKASEATTNSESEVKNNGTITIKNEEYSDVIPVGARWCFVFGAALILLIFTIIQSCHISVIHSCNVARIKRTIIRVGISIGLGLFAAFGEKVPTLETMIIVAFTMIFLVSFEEWGRIQSKKRNGNGEDKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XVX9</accession>
    <name>A0AAD5XVX9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-arabinono-1,4-lactone oxidase</fullName>
            <ecNumber evidence="2">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001540</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010001442">
        <property type="protein sequence ID" value="KAJ3203358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XVX9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="18"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3203358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="477" mass="54826" checksum="F5A509EAA40FE467" modified="2024-05-29" version="1">MSTNFLNNPVYNWSKTKILSNYNQLHFPNSISELRSLVLNHKKVRCIGSKLTYNNLTKVSNENDSILIDIKNFVGLIHLDKKKNTAKFWAGTTIKEISETLEKNSKYFSSSTGVIGDQTFAGALGTGIHGQGLHVVPFVDTLKEAEIMLASGAIIKVDSKKKNFLDALKTHLGVFGIILTITIEISDLKIMTCKKKTISLDKFEETFIKIQRSEKYCKGWWFPDFDLVHIWEADVANEHELELYEKNGRNLVNVHQNLDNELSKSIDLLEKRMKTDTNDDSTAGKQFQTISRFRNVVNVTGTMHQVYMKGIPVPQINCEIAIPIKNFELSLKVLKKWKNETKFKLHYPFIFRCTAASEALLSPHRGEEICWIGFLVYLDSEGNAAKGSFEMMREIQQVLLPLGGMPHNGKYFDMDLYNLEKFYPKLKDFLFLQKMLDPEQKFQNEYTKKFFAAYCHNKTTCNKVIEIKNNNLLESRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWL8</accession>
    <name>A0AAD5XWL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_007056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000653">
        <property type="protein sequence ID" value="KAJ3214053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWL8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF34">
        <property type="entry name" value="PROTEIN ANGEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3214053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="253" mass="29476" checksum="409434E7E0C1CB2F" modified="2024-05-29" version="1">MFVKHNVFDIVQSKYTHLERDNIGLTLLLSFKKDPKIKICISNTHLLFNPKRHEIRLRQYEALHNEAKKLMSEFSTVQIPSILCGDFNMTPFSDTFRSIVKEYMTSTSPRHPLNGKNFRTFLGNENKIVDYIFYKHAKTMKPISFLSPIVDEGCHSLAPNNYHPSDHCFMATNFGISENTDPTYDWDMYDFSIPNSQSEKPKKTTITEQIVDESVTVTNTLSFSNADDVQIKFNNTFVKRRKFTRKKKKIILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XWQ6</accession>
    <name>A0AAD5XWQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001001">
        <property type="protein sequence ID" value="KAJ3208317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XWQ6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5041939327" evidence="1">
        <location>
            <begin position="25"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3208317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="229" mass="25200" checksum="CAD68A9451E1A4F0" modified="2024-05-29" version="1" fragment="single">MKSTSSVFSLTILIFLFLFTALSALPVASNLTLNKRSPIDLSYWLLQVPQKNGVYASNGKLKYWVYPPNLQTTNSVSSPKSGYQVFSKSSTDLTLTNSIKDEVGAAGGSTSRTELREYVKGQANTQALWNVKSGTHIMAGSITINQCASGCSSNNLNGGAMVLGQVKGSGSEIISIRYFTDYDTKIQNGKPYLRRLQLVYTSGDKIIAVPLDEKFELKQRFNFEFKFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XX93</accession>
    <name>A0AAD5XX93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_000971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000125">
        <property type="protein sequence ID" value="KAJ3223550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XX93"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="entry name" value="Globins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3223550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="188" mass="22930" checksum="7DEF43A8D6D77AA0" modified="2024-05-29" version="1">MQLFVKWSKKEEFKIKKSASIFQNLGEARLLSLTKRFYDKFFKDEHLKKFVKDPTEPHGERLALYIQEKMTDNLVYTSSRPLNSRSIHHAKAWFCPKREFEKQGRRFKLDDCRIWMRLMFLSIKEEGLHTFHHGEFLDYMIYFIKRFIVVYERSAYNFVKESLEWSFQIESVLTYEKFPLMLDVIEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXB1</accession>
    <name>A0AAD5XXB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 19">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="6 19">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">DGA1_1</name>
        <name evidence="23" type="ORF">HK099_000846</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 19">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 19">Endoplasmic reticulum membrane</location>
            <topology evidence="1 19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="6 19"/>
    <dbReference type="EMBL" id="JADGJW010000121">
        <property type="protein sequence ID" value="KAJ3223671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXB1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17 19" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="12 19" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="7 19" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="15 19" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="21">
        <location>
            <begin position="239"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="22">
        <location>
            <begin position="389"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="332"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="424"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="337"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAJ3223671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="495" mass="54694" checksum="9E14C56AF316E5A8" modified="2024-05-29" version="1">MWSRWLRKLSYWRWLADYFPMQLVKTSELDPRKNYVFGYHPHGIISLGAFTCFGTEARDFSKLFPGINVRVLTLTTNFFMPLFRDLLLNLGFCSVTRRSCENILSSGPGNSILIVPGGAAESLYAFPGVYDLVLKKRLGFIKVAVRHGASLVPVIAFGENGRGVFQYSYGILPHRRHLTVCVGEPIEVEKLENPTSEQLLSYQKKYLDGLENLFNKQKELYAPNRKGELTFCDHDFPTHSVLTMPALSPTMTQGALGTWHKKIGDEIVPGDVLVEIETDKAQMDFECQEEGFLAKIFIEGGTKDVPVNKPIGILCESKDDVAAFESFTLDNLSPAEGSKESESSKKNEGQKKEQPSPKEKETLSKDSVTKEDSEGDNVEVGKKGSVRIFASPAAKALAAEKGYEISAIKGTGPDGRIVKADVESYKPSSTPQKAKEAPTAKAPSAKAPAGVSYQDVPISNLRRVIAQRLSESKVRTLNIVVLLKSFKSPQFLTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXC6</accession>
    <name>A0AAD5XXC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SPT2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HK099_000685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000117">
        <property type="protein sequence ID" value="KAJ3223792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXC6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013256">
        <property type="entry name" value="Chromatin_SPT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691:SF8">
        <property type="entry name" value="PROTEIN SPT2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691">
        <property type="entry name" value="YEAST SPT2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08243">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00784">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="66"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="357"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="428"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="479"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3223792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="631" mass="72320" checksum="1AB9708AAC7389F6" modified="2024-05-29" version="1">MEFGELMRLASQKAKHDEEKQKLKQQAMEKEKIQREKEEKERLIKQKAFEATKILANNLSTELDFSAVKKEPKKNVSSQKSNAKQVCTSPLSSNSKKSLKTLRGDSPDIAPVKKIKNFKQLMKEADKVKSQTEKLLKGGDTNSNKGKKLMMNENLSLNGKESSKKRDDSTTYSNNHGDREKGLIKDGRPNSDYRGNGKQYSATSHVGTRETQFKSRGDGEDNGPPSENRSYNRKEERNYQTNDRKIHSSKNEISRDRDEYEHPANLHEKTGSKHLSKQYDRDKEKSNSLKEFKQRTTDTERYEKSETRISNKDVQKPKQEKPSDFITKPIQKYDLLSKPKLRRPEDEILTKSNSTDLLSKPKLKNPNLPTSKNSNNPLFITKSVKKIKSASTSPNSSVRKKPNFAQSSIGKLGNKLGIPSGLVQLNTKKKDTRSTEEVQEELRIKKALASGKPIEKKRSTSPRPDGVRVINRGGDKPLTNFSVHSIPQQQKMQVKNQNSGGAQKKTSSSSNGTRVRSTSLDDRNMMKKKRKFNDEYSSEEERIVRKRKGVDEALKDPEYLSNNYSSVIQQMFGYNRNRYRDFSDDSDMEAGYDDLRREEARSTKLGRKEDILEEERLEKLKREKEKKKGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXD7</accession>
    <name>A0AAD5XXD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001175">
        <property type="protein sequence ID" value="KAJ3205792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXD7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051283">
        <property type="entry name" value="Sec_Metabolite_Acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896">
        <property type="entry name" value="FAMILY REGULATORY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G14730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31896:SF64">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="459" mass="52605" checksum="3B7E27D93191AA87" modified="2024-05-29" version="1">MTTIVKSYRIKPSKPIVEIKKETLEGLDKNNYFYTTIFFGFDSNYFSPAPNSIGYEQIVEKLKNDLSILQNDFPMISGNIENNYEKNFAQIIYDGSGVVIIEARNNSININDLTILKDNNDFTSAKTISDLFTPDLKFLKNEFHVQHFPFIVQITKLKCNSIILTLMNSHMLMDGGSYELLQSAWKAISKGLDYRKPDDKKIDYAGIKQPSVMPKGWMEVPKKLFFNDDSTSTDEPSQYIPSCRFHFSKNKVNQLKIELNNLIKEDGETKYVTSDEIVCSLLWKVITKHRKLDENQNTTFIRPTNVRNILKPMLSDISFGNLAIMDGISLTFKEINSFDILQIIKKIQLQKELYKRDIILQNLKYFTELPFDKSLAMDFVGLAKTDLLLNSWSKFTSLASFDIGFGNNVFVSLPPLMNGAVLLLPSCFKQEEGIVAHTYLPHSVLQELKNDSDLLKYLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXJ2</accession>
    <name>A0AAD5XXJ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosducin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001085">
        <property type="protein sequence ID" value="KAJ3207009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXJ2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051498">
        <property type="entry name" value="Phosducin-like_chap/apop_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809:SF3">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="2">
        <location>
            <begin position="19"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3207009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="246" mass="28811" checksum="3262CA73C2F359D2" modified="2024-05-29" version="1" fragment="single">TEWNQILREKGIIPEITKEEIEEIVEKVIQEKESLDNKDLDELDELEDLEDDRVLESYRRKRMQEIKDYQSKAKYGTITQISKPDYQKEVTEASKNLNPEYVVLFLFNNSLPESRLVSAYLTSIAKKYPTVKFLKIVADQCIENYPDTNVPTLLIYGRGELLANLIGINKLGGTQTNFETLEFLISSYGTFEIKKEKLFKDEEEEENYRNRNNSSANMFNLNNKINKKFQNETNSSKFDDEDLDWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXK5</accession>
    <name>A0AAD5XXK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TOR1_7</name>
        <name evidence="4" type="ORF">HK099_007450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JADGJW010000720">
        <property type="protein sequence ID" value="KAJ3213356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="3">
        <location>
            <begin position="837"/>
            <end position="1398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAJ3213356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1487" mass="169567" checksum="FA81A8FF9BAEC9B7" modified="2024-05-29" version="1">MFSSGIISQPLIETLEIVKTNFPIYKSKIQLQLINLISRILCEVPYFESYESSFDIAKYHKEKIDFQKVVVNESTIILAWKTLSSFDFTGFRLNFLVESALRYLEHEVVEVRKTASVTVASLISRNTAFHQTSSDTLKSVSNIVEKLVKRMNLDPEYRIRETIFLSLDKNVDSLLATPENIKFLFFAANDNFFEVRNLSIKTICRISKFNPSLVLPRLRKNLIKILYQLEFSTIPELKEDSSKILTSIVQNVQVEFLMRYVDPLSKSLIANVNSDQVGVASTAMECLGELFEVAASLMADKIDHLITVILHSLQSSKKLSALKLLGKIAGSAGITTGLYVKYPSLLNIFIDLLKNNQSSFVKKEVAICMGRIGAYDPSLVSLNSDSIAAATSDVVLLINLPKSDEFYAPTFCIRKLMEILVDSKLDQYHLLTIQTVMTIFKTLGSICSRFTGDVIPTFFLLMKSPAINSQMLNFYFQQLTQIILIVKIGMTPYIPELMTLVFKYWNSASNSRIIYLIDAISKFMIEELKEYFPTLIPKIFEKFESKNNYDKEEPNVELKLTVFEIIIRLSVHLDDYTNIIIPVILQVLNDDSESVIIQAESIKTLGKLFLIMELDDQLSTITLNLINILKKNANTQIQCEILESFYLIAVKSKFQFEVFIPLITDVLNLKNLSNYKLEELFFKIKQKFDIYEFDNIQTAYEGTLLNFEQLSIETSSKLSTNQTRLKKVWQVSNFNSDDDWYNWFRSFSNELLLQSPSQSLRACSNMANIYFPFAKELFNVAFLSCWNELNEANKKNLVSSLELTLNASSSLELLYAILNLAEFMEQDNKPLPISTNVFAAHSLKCHAYAKALYYKERDFLNHPDSANIDSLINIYNFLDLTDSSIGIIRYHEKAKTPGDLDNKSYYLPTSWYEKLNKWDDGLVAHERNLLDDESFNVYSTRNSMNFFSAFGEWSKVLQLSEDCWNKASLSERKILSPIAASAAWANEQFNLMEKYTETMSDSADSLFFNSILALKNNMSSADAMPFIDKARDYLVVELEALIGESYSRAYSVIVRLQMLAQLEEIISFGSASAEKQKVIATIWNDRLSGCQKSFDIWQKMLRIRSIVIKPKNDLTTHIKFSTLCRKSGKLNLASKSLLSLLNNQPANGDLKSLDTKSEDPRLVYAICKHLWESSTNGVEKINIIKLLKKFCGEFSSTIGIFKVNDINQQLSSLHASWKINLLSKIFTKLGDYSLYLQKDNFSKEAIPHITSLYGAATKCSSSYSSNNKFALANLEAINFFERNTAEANLNVFSSYVISALKGFSKSILLSHGRNSLQDTLRFLSLWFKYGHQPEINEVVVDLISLIPLATWLQVIPQLIARIDSTSIYVKGLIQKLLMTVGRYHPQALVYSLSVTSKSEKPVVRSAALTILNEMSNHSSTLIEQALVFGNEMIAVSMLWREIWCEGLLEALFCYRKRDIDEMIFRLDLLHKETDKQNPKTQNEIDFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXU1</accession>
    <name>A0AAD5XXU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000650">
        <property type="protein sequence ID" value="KAJ3214095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXU1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="185" mass="21725" checksum="E65B9370B34B0A3E" modified="2024-05-29" version="1">MILQKQLQFGFNVSGFEDGFDRRLRGLCKGWLDDLTCKTNSREWELLNSEICFLEYVKKLRKEEQPEVWLLYGARYYGIEGDVCFENYLKDLKPDLRNFSLNLCLSRQEVGKGYFKGYVQNFIKTNQSDILNFINGDDAGIYVFDLNAAFIDIINEQKQDVKGIEILSKLTEGKRYVREIWVLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXU7</accession>
    <name>A0AAD5XXU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_007010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000646">
        <property type="protein sequence ID" value="KAJ3214144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXU7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3214144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="312" mass="36786" checksum="56E70BA7BFC2537C" modified="2024-05-29" version="1">MNFEIFKQLSSPKVCEVGDAAFYCICYINSLENNIFATLRNTQLFQQLKRELHLNGNFGRVSNFYSNLHITLEKKYQIPKNVLSNHDTTFNQQIINELRSFIISNVENFIQILPVEKKKFSSSSACIAGHREIFNHYNSILKNVLKLLNKVIFFFRNDDNFEIISLKKKSKHYLSNRDCRGSQLGLKIKISNSSSNNLLGIKEKKEWYRNFSREFQKYLDHTLQQKCWPRPEDAEKIRKLCCDGFVCGLTTTEEEEEESYLTRLDMDFYDALEGENEVIIWWKLGIDNNFLFKSIQDLNSEKENLEIVEYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXV1</accession>
    <name>A0AAD5XXV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <ecNumber evidence="6">5.4.2.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cofactor-independent phosphoglycerate mutase homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HK099_007643</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000076">
        <property type="protein sequence ID" value="KAJ3224923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXV1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1450.10:FF:000001">
        <property type="entry name" value="2,3-bisphosphoglycerate-independent phosphoglycerate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="entry name" value="BPG-independent phosphoglycerate mutase, domain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637:SF0">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 15" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="16">
        <location>
            <begin position="3"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="BPG-independent PGAM N-terminal" evidence="17">
        <location>
            <begin position="82"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="13">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="152"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="255"/>
            <end position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="394"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="398"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00083354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAJ3224923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="508" mass="56888" checksum="D78278225B28E5F6" modified="2024-05-29" version="1">MEKTCLIVIDGWGINVDENAKGDAIKNAKTPVMDKFEREYPFVKLAAHGLSVGLPDGLMGNSEVGHLNIGAGRIVFQDIVRIDEAVKKNVMLKQPDLLEAFEQAKKDGRLHLLGLVSDGGVHSHILHLFHLIKLAKEFGIKKTFIHFFGDGRDTAPRSAIEYLKQLKSKLQELNYGSVATVIGRYYVMDRDKRWERIKIAYDALVSGVGEESIDLEKTIQERYSKDETDEFLKPIIGDKEGIIKDGETIICFNYRSDRMREISQALGISPLPFDSKPLKNLNIVTMTRYKADFPFKNIFPVQSMDNVLAEWLDKKNVPQCHIAETEKYAHVTFFFNGGTETKFKLEDRDMIDSPKVATYDLKPEMSAIPVAEKVASRIGEETHPFIMCNFAPPDMVGHTGVYDAAVHAIEATDKAIGIIYDACVKHNYTLFVTADHGNAEKMLAEDGITPHTAHTCNKVPFVMTSKKVKFQKDEGSDVGLCDVAPTILDFMGIEIPKEMSGRSLLDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XXX1</accession>
    <name>A0AAD5XXX1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_007494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000073">
        <property type="protein sequence ID" value="KAJ3225021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XXX1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="195"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3225021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="253" mass="28218" checksum="D9153BB3AEE1D72D" modified="2024-05-29" version="1">MAASNLPTAQSQDNFCFDDLLIPKLNQSTYFPTPVLSESNSFLDSPLPYSNEFFSQLQHHSLSHPPINPSLFNPSPFTSYQSPFMNSADSIVSSSPVIDQLNYFEPLEQQQSQIPAVNPSDTVTLTFAQLSALIAASNKLNEESTSTPTPQKEPSAGKAQKSFPCTFPGCGKIFSRKFNLHTHTFTHDPNRPRDFVCQENGCKKTFVRIHDLQRHATTHLPKENVCLRCDKKFGRSDALARHIKSKCTSVKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XY96</accession>
    <name>A0AAD5XY96_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HK099_006980</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000064">
        <property type="protein sequence ID" value="KAJ3225335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XY96"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000340">
        <property type="entry name" value="zinc finger protein 473 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAJ3225335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="266" mass="30062" checksum="55ADB814A7A4BB30" modified="2024-05-29" version="1">MWELTHPPTCGTCSKTFTRPEGLKTHLLSSGHGPGIDIDLKGGSVKDPNDMDVDSVNIALFSKRIFKCELNSLKVHFRSIHEGIKPYSCVTCLKSFAHKHLLARHTRVHIQKIADSETMESLEEKAEEEKESEVSNSEKLRKETELKCLLQLTGCDYNLYTKETGRILICPVNANSNLTKNLSCKMQFKRIYDLSRHIDAFHPEVKKNIFNATDISFDNDDRMLSDNIYVGEKLVVMSNITSSMVTANNIVIWNTAGDRYPAIPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYI6</accession>
    <name>A0AAD5XYI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_006136</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SH3YL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000051">
        <property type="protein sequence ID" value="KAJ3225838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYI6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11525">
        <property type="entry name" value="SYLF_SH3YL1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000100">
        <property type="entry name" value="SH3 domain-containing YSC84-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033643">
        <property type="entry name" value="SYLF_SH3YL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF2">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="355"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="247"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="294"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3225838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="414" mass="44507" checksum="79CEF373C0ABC0C0" modified="2024-05-29" version="1">MAKDIKFNSPLPENLQGECKKAVSILEHLIKAKTSEVDATFIPKKILENAKGVAVISILKAGFGWSGRAGSGLVVARLGDGRWSAPSCIGVAGVGFGAQIGAQLTDCVFILNTPDAVKAFSHGGNVTVGGNLSVAAGPVGRQAEAGGSFANFAPVYSYSKSKGLFAGVSLEGSVFIARKDANEKFYHSKISPAEILEGKVEPPVEAEALYRILNIKFGSTPVGSSEALSHNNYDGSHEDRVVDRRTSWASGTPSSVHHSQSPSRYSTCPSTVDYSTSADPVPYTYQDFLNKEVSKTGSNSTPVLNRNSNYLPNSASYTSNTYSATPDNYPLKTSEKQDYKRTSAPPPPPRYVPRSSVEMVEALYSFQGQKNTDLSFEKGDLIEVVKKTASDNDWWKGRLNGKEGDFPANYVKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XYV3</accession>
    <name>A0AAD5XYV3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transmembrane protein 231</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_006850</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM231 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000618">
        <property type="protein sequence ID" value="KAJ3214471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XYV3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060170">
        <property type="term" value="C:ciliary membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032880">
        <property type="term" value="P:regulation of protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019306">
        <property type="entry name" value="TMEM231"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14605">
        <property type="entry name" value="CHST5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14605:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 231"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10149">
        <property type="entry name" value="TM231"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3214471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="134" mass="15561" checksum="043DA66E1BA99245" modified="2024-05-29" version="1" fragment="single">MDEENKENINSINVAFQFQYDLTRRFKFGMICLGVLNFESSLGVNSVLMTGRFNLIQDTLFPFENIGEAVLNYTKVFKGGGLVWDDFIKDYYNRPIRLEIISNTPIYKIGTSKNLIVEGRISFREQEILYQPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ41</accession>
    <name>A0AAD5XZ41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RING finger protein 32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RNF32</name>
        <name evidence="3" type="ORF">HK099_003344</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000022">
        <property type="protein sequence ID" value="KAJ3227125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ41"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16677">
        <property type="entry name" value="RING-H2_RNF32_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042862">
        <property type="entry name" value="RNF32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14991">
        <property type="entry name" value="RING FINGER PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14991:SF0">
        <property type="entry name" value="RING FINGER PROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="360"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3227125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="416" mass="48472" checksum="78CB90B4D512E599" modified="2024-05-29" version="1">MQPSKELKTNSAINASAFQDHFMKTLNLGNLQSLHTKPKSKHVTSWSQKIIEKNKNQQKKVNSLNKNECFKVNLKKKLEILKFEEEKVLEEGKIIKKSLAEKIGLIEQKKKLSTLEWETLKVKSIERGELAKNGNCPICQEGFKFEQQVLLSCSHVFHRQCLESFERHVNKKSCPLCRAQGYEKRLIHHGKKSWIENCIVTIQKTFRMWRIRKTYLQYRQAYPPSNPILASKFYLDKLTKCNDALIKKTKIEKFNLDSFFKQLDLEVAKSKEIVERTTAEICKLSALNSDELTFEEWDQVFEKAKNREKFEEGDSNCSICLNLMLIKDPSIGVNEKAKINSSKFVTNKKKKVEQITSSKCVQRIKKEPKKLVLLSCSHVFHSTCLSCFEKLDLNIFVKFCPICRSEYQKMEVDEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZ93</accession>
    <name>A0AAD5XZ93_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ATP4</name>
        <name evidence="15" type="ORF">HK099_001928</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000016">
        <property type="protein sequence ID" value="KAJ3227472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZ93"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008688">
        <property type="entry name" value="ATP_synth_Bsub_B/MI25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05405">
        <property type="entry name" value="Mt_ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161060">
        <property type="entry name" value="ATP synthase B chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="541"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAJ3227472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="671" mass="76617" checksum="8F195D64D4A76F44" modified="2024-05-29" version="1">MKIIELSKRKKEKPLFTLTITHTTFPSTNTASISNALINPTLSLPISLTSTSIYANPTFIPNTYNDNDNEPLASKYQINNLLKRILEISLPLFAVFMLIALLFTYCMFKRKLKQRKNLKILEMLHEQQLQQRSNCSISKSSASSFEIKENTKIRWKSVISSRKSGIHEFYDEIEEKKNSEIGKHAVKEKLHPTGDANLKSILKVKENPIINKSLPWQSSVQAWLLNKADANPLGIIELNKKIFYNLPIRQDLIKRSLMYEKSWMEQGTESTKNLGQVRGSTRKPFPQKGRGKARVGTLRAPNFKGGYNVHGDRPHNKKINIQKKVYDAAIRAALSAKFQQSQVIILNDLTLDNDDKSSLRSLIKTFGLEGRKIYFIYGNEEPEKFLIRSSNQFIYKKPDVDNPKLVNGEKPILVTSARNVSVGPLLDFEILVLDKLAVEVLEQIFPSLIRKNGLTASNNLLKNLVRPYSSEKDPKETALNLINMFPGKNMVAKTSSILAASSIAAFAISKEIYIIDAEFLEMWCIFGAYFVWYKAFGEAAKEYLRERKENVRRVLNEARNDHQAVVQERMNHIGKLSDVVEVTENLYGMSKELAKMEAEIFELKQRVNFQQEVKSTLDSWVRHEQSVREKQQQLLAASVIESVTAKLRTPRMYDQILAQTLADVEQLTKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZG9</accession>
    <name>A0AAD5XZG9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Gluconokinase</fullName>
            <ecNumber evidence="3 9">2.7.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HK099_002029</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>D-gluconate + ATP = 6-phospho-D-gluconate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19433"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate acid metabolism; D-gluconate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the gluconokinase GntK/GntV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.12" evidence="3 9"/>
    <dbReference type="EMBL" id="JADGJW010000164">
        <property type="protein sequence ID" value="KAJ3222666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZG9"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046316">
        <property type="term" value="F:gluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02021">
        <property type="entry name" value="GntK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006001">
        <property type="entry name" value="Therm_gnt_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01313">
        <property type="entry name" value="therm_gnt_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442:SF3">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3222666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="172" mass="19958" checksum="EC3A1D359215B5AF" modified="2024-05-29" version="1">MGVSGTGKSSVANLLREKLKDCEFIEGDDFHSEENKKKMSAGIPLNDDDRTPWLLFLNDRLRCSTTLNTIVACSCLKLKYRKLFQSSKEKKDQLKFIYLYGKKELLEERILKRKDHFAKINLMESQFEDLEPPTSEELTQNFLGKYNVEDDLKTIVQKILISIQEYSPSLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZJ0</accession>
    <name>A0AAD5XZJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor SLU7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SLU7</name>
        <name evidence="10" type="ORF">HK099_004566</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLU7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000326">
        <property type="protein sequence ID" value="KAJ3219803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZJ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030628">
        <property type="term" value="F:pre-mRNA 3'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021715">
        <property type="entry name" value="Slu7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039974">
        <property type="entry name" value="Splicing_factor_SLU7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942">
        <property type="entry name" value="STEP II SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11708">
        <property type="entry name" value="Slu7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor SLU7" evidence="9">
        <location>
            <begin position="655"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="707"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="992"/>
            <end position="1011"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3219803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1011" mass="117715" checksum="8ACD4A5F68684B8B" modified="2024-05-29" version="1">MSNFLEILKLSKILFHFEFSSKFTELEDLLNDDKQKSLAKQCNDFFFKLKKEITSCVANCDNLFTAPLETFKQFKLLLVDNKVEFFCDKSEFLYDIVKKISETKLTKKFVLNNNSAVHSNKIKIDLKSKRDKPYLNLPEELLLKIFSPFEKDTTNLLKFSLVNYKWLRLVRHMVYDTSVLLPWTFVPFMITLNSNLNFIKCVNKSWPKIIVSKLYFDICWNSVETELLSSLFLQLTTLTELHSPLSFDSIAKVMTRCPLLSTISVGYSGFSDFTFDWTCDSEYLNNLTQIKNLKFYEFFSIKEIDKESLKTLAFKDLETLRFETEGECYWILKFLLNGTVKLRELVICPKNYAEQPLDIYEVLKETKQPNLMYLELKGCNVDSKTLELIKSKFLILNTLKIGDFSQLDLKNRDFDFLKQLLKGGNKHLKGIFLNLDGELTDKILREVSENLPNLVNFNVKFNSGSTNLNFKAVEEFCSSLPKLKFIRNSYFSDEILQLFKNFYVYVEDTPLYNGDFEDEISCYGNEIDDFRKQKVIDEARKSGTIPAEVDPTTGKDINPHIPQYMSQAPWYLDINHPTLKHQRNTVEEFRTDLDTWYKRGEKQGPAATKYRKGACENCGAMTHKKKDCVERPRKNKAKYTGKEIQADEVIMDIKLDFDAKRDRWNGYDPNQQQATIEEWELIDEERKKLREEEVKKNLKLGINLDNSDDEEANEDAKGYGEDMDMPGTKLDTKTRTTVRNLRMREDTAKYLLNLDVNSSYYDPKTRSMRDNPLKHKDPSELSYAGDNFVRYTGDAPKHAQLQLYAWDQAKKNPDVHLLANPTQVEMMNKKDMSQKEAKTNVLKGSIIEKYGGEEHLKVPSKDLLLAQTEQYVEYSQTGKLIKGQEKAVAKSIYEEDVNSYCSGKAGKEAMKASEEMMIKKLEQKKKEQLNKPLVNKKSTTEDSEELDKEKLEIALKNEKARNEEGATLNRKRKYNTAEDMKEVTKEELEAFRINKQRNDDPMLHFKDDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5XZL8</accession>
    <name>A0AAD5XZL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dynein regulatory complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HK099_001645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DRC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000149">
        <property type="protein sequence ID" value="KAJ3222986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5XZL8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003352">
        <property type="term" value="P:regulation of cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039505">
        <property type="entry name" value="DRC1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039750">
        <property type="entry name" value="DRC1/DRC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029440">
        <property type="entry name" value="DRC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21625:SF1">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21625">
        <property type="entry name" value="NYD-SP28 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14772">
        <property type="entry name" value="NYD-SP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14775">
        <property type="entry name" value="NYD-SP28_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein regulatory complex protein 1/2 N-terminal" evidence="5">
        <location>
            <begin position="181"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein regulatory complex protein 1 C-terminal" evidence="6">
        <location>
            <begin position="812"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="270"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="329"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3222986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="894" mass="103530" checksum="7852C544537D9233" modified="2024-05-29" version="1">MEAANQLEIINSISEQEESEPQQSSPPTANTQELLVQEKEFDGVTQNEQNNSSNNNNEEPPTQIQPQNDANSIPVTTNTNTVGGTLGNLSPKQLQLKKYNQLIDLTRENRIQTRKARIQATRLAKTRTENAEEIAAMLKPTSEPERKDAGKSKNQIIQSKKRADAIKLHSTEEVTTVKAQVTAREAQRRLEEVRKIELKEERRKEEQKKSIEIQQRIEAEWEKSFNMKLPFELRESLLIQKAACDEAITIKNKLCNEFISELKIKDDEYVKELKRQAEEIDSMLGKMETQYKAFQNTLNEEINQIDRAFVEERTESMQANNAEIEKIFVSRRENERKFMEERADRIEDHISQLEQLRIQDAEEYNLVKIKLETDVKVLEQQLQQMRGTYQLNTEKLDYNFQVLKKREEENGTILSAQKRKMSRLTDHLNTLKIKIGKQEKTFHSEYLALTEDYKRITEQFKELQKKFRHFQIADSKKYKEIWAMNEEIAKEKMRKVLQADRIIHEQQLGLEWNPPDEEIFSTVEPSPIADIKQFHKQPEVSKLEKETGAAAHLIAAASLNEEMDDEEVSFKETFGLKLSKKGYSKTMKKMLELLCNEAGFLVEERLQKLLAPLHKDEQSLMKLDSIFKAIGVSTVEDIEHLTSYFIQTPVYDKHQSSTENSHLLKLEAEVNITSPHLPIEPETEGSKQPLNNLQLSKDEKMLSSTEIHNDLTSHFIGPNEVVKAIRRFAEDSRNEKERMELESSSSMPSLVKNTVSDKKIRNNDFGIEEEDEDDVLSLTEQGKSLMKNLSGVDSGKSQVVCGDQKQKNQECYWEKFGKIVNDSNYRTWSAVYVGMEKYNQLLSERWQLTQEIGSVSRQNEELRQLLRQYMSAEVNDELQVPPTKIMLAQAGLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y041</accession>
    <name>A0AAD5Y041_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Inner nuclear membrane protein enriched at telomere/subtelomere region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SRC1</name>
        <name evidence="10" type="ORF">HK099_003705</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000246">
        <property type="protein sequence ID" value="KAJ3221174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y041"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1180">
        <property type="entry name" value="MAN1, winged-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044780">
        <property type="entry name" value="Heh2/Src1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018996">
        <property type="entry name" value="Man1/Src1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041885">
        <property type="entry name" value="MAN1_winged_helix_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808">
        <property type="entry name" value="INNER NUCLEAR MEMBRANE PROTEIN HEH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47808:SF2">
        <property type="entry name" value="LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09402">
        <property type="entry name" value="MSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Man1/Src1-like C-terminal" evidence="9">
        <location>
            <begin position="201"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="71"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAJ3221174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="627" mass="72077" checksum="CDF4BE6A48AF7D70" modified="2024-05-29" version="1">MSSRTPKQRLKENDDRFLAKTENTSDVNCFQSNTPLKIDSKKKIESSSKSTSSAKMTKQIDNFIKIEEVKSSSSGATHSKLSKGSSASMATPKKLPKPDVANFSAKNLSGRTPVTTIPQIETPNILKSRTKRKVQEQWETSEFRTELTPSVATPYKPPTRTQFNKSFRKRINEPSILPFLAFFTILVVLFAEFMINNKLKYCGPYNEENTYEGWNPVNLLFPNCLTCPTGARCIDDILVDCEAGTIKKSTLIQKILPAKFLPFPFNQNYCAVDEKKLKKESLMEVERKKKLKDIEVLTEFVVRSWLGKLKCLDFGKEELKDIKSNYYYIWKDSQIFGMPINLAKNLVRDKVLEGKFTKNSALKINNNLNIDDFENIWDEFLILMISNSNLRKSSLVLTRMDPHNLNHRLIYSKKNPIENFSCTLKLKTLNFLKGNLKSLSIISFITLSFFWIKMYADLKKKRDDICTVVVDDVFTMVAEECDNHFLDNVRHPIPGLAIQHLRDFLLRTNKKPSFTEMIDGKTIFYLEKEEKDLIWKKVSAKVLENSNIRETCMEVNGEPQDIWQWIGSAALSPSKKKTTVFAESIKIEKQGNIVKSLQKNEIQFSRTYKENTSPLKTKSDIEEISLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y0B3</accession>
    <name>A0AAD5Y0B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HK099_004369</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000305">
        <property type="protein sequence ID" value="KAJ3220420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y0B3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="106"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="319"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="558"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="569"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAJ3220420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="599" mass="67097" checksum="25AAE155DBCCB7FD" modified="2024-05-29" version="1">MWKKHKELLPVLKISSLLSSNSCILLSKRCLLQLSSVKGVGSSVCPKTFSVNFSTISEVHKEKKIAKKLNPISNDFSSLDLMDPIQESLNKVFKFEKMVGCQQPVLSSLPTAEDMLVKAKTGTGKTVAFLVAALEKLKNNSPNTWNAVLAGRHKVSILIIAPTRELAIQILAESQKICKFLPLKSVLICGGEMKRPQINNLTKQRCDIVVATPGRLLDILHSNEVMKTIFSKTRILILDEADRLLELGFKEEMEKIMTFLPTKERETLLFSATLNKETKHVAASTLKKNYLHIDCIPENEVESHHQIRQSYIISPFSQQLPLILDIIRKSKESNPLSKIIVFFPTANMVGYFSQVFNAIIGLEIIELHSRLNQIQRVGASKNFRAAMGGILFTTDVSARGIDYPDVTLILQVGIPITRDLYIHRVGRTGRAGKDGEAIMILSPYEKPFLKELNNLNVKEDVRHSPVFSASKKENIAKLQSIIRKAPKQESMECFFTWVGYMRGIFGKHKLDYEKINAASSEFAKHMLGIASPPTINKETDQKTRLHNLNEEKTNVNISDETGTMEGGRNTVQTRGSPKSSSFKVRKSTNRIASKVNGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y161</accession>
    <name>A0AAD5Y161_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_005148</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000039">
        <property type="protein sequence ID" value="KAJ3226317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y161"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051637">
        <property type="entry name" value="Ank_repeat_dom-contain_49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR 2C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24180:SF45">
        <property type="entry name" value="POLY [ADP-RIBOSE] POLYMERASE TANKYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3226317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="341" mass="37211" checksum="E7014687B62C4B9C" modified="2024-05-29" version="1">MRLHLKSKDLAKTKFKASDAPAFVYNEANQIGKNSTLVDLMTRFALEAVAMLGSFQGSLNEDDKAANSPTSPSTNSSVSSTSYIQIPSNSLPINNHNSSQLSSSYHHSSRTSSLSKSWSKSRARRKSLESHHSSNKVKHNNKSKPDLGLHNAVLNSNYGLVKFILDQGQSVNSITNGMQPIHVAAGIGDLKIFELLVNRGGDINGKRLQKNITQSDLNPLDALNILYGSTPLHFAVANNQIEIVKKLVNLGCNPYIKDEFGVLPIEISIQLKNTVITNLLTKLMKDFDNGVNGVGFNSTNSSSNFNHNRSSSSVGSNFYYKRGNSFDRGGSFDNGSFRSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y1V1</accession>
    <name>A0AAD5Y1V1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HK099_001401</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">JEL0476</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="JADGJW010000139">
        <property type="protein sequence ID" value="KAJ3223213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y1V1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF1">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ERV2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAJ3223213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="62" mass="7463" checksum="EB68DEB58DB046F8" modified="2024-05-29" version="1">MSEMTNATLKQELGRAGWRLLHVMAQKFPFYPTFEEQEKLEQFIYMFASLYPCGDWYELVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y291</accession>
    <name>A0AAD5Y291_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_000291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="JADGJW010000106">
        <property type="protein sequence ID" value="KAJ3224079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y291"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18785">
        <property type="entry name" value="SF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="428"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3224079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="1158" mass="134156" checksum="E6E37F59B036806C" modified="2024-05-29" version="1">MDSNRNDKKDSNKDNNKDIIDRSVGINSIQSILKNATQSNLSFFHVAGNVESDSVLPRPSVADILDNSFVSKTSCTVRVKPGHEYGLRKRIMCTRVRDFVTHMNSSILNHHQDPWDCFWKEDIDKSYFRFYFDVRKMASLAITMKDIADTFQNCNVVYSPDFIGILDVFYERKGNWNNIILHLDNIIGGDEKIKNAIVVKDSEEVITLNVIGSSIECLANNHEHILFETLTVNDIPDIYMNFGIEAAREVIYDLLDSQKAGLVADFMCRSGEVVSIGRKSIKKFDRGFASYTFFERLALGFRELDTPRVDRLTSVYSKIWRGIRVDDDSYSLKIASEDNKQTVEPTDGPNDGEPVNDEFIDTDDNSINIQHNLILEESEDESEDSDMSGMYPNITKNIQTDIASMLEFRALDNKENLFRHQEFVRRYMSPFTPYKCLLIFHGLGSGKTLTSLKVAEDHYKHDRKKTIIITKGSSAEKNFKYQIQKFNIQCSDAKYYHYISLSNMISRTNNNELESIFSNAVVIMDEVHVIKNHIEEESVIGRLETCVNMAINSKFLFMTGTPMINNEDELNIIHKLCNTDSLLGYISYTRISINKPKYTVENIISVMGDYQIKEYLNESTRSNDIFKKITQISLFTTHDGYAGRELDSNVFHKKTLISMVVNNKIVKKGVQHVIKPEYKKYLKGDLLKKCSGKYYELLNIIKTHTSGKIFIFIEDVIGSGIKILHKILEENDYQFFVNDNITTDPYKRNFTTCTGNGIESPDNMSKINFFNSDENINGERLQILIGSKAIGESINLIGVKYFHYLSPHWNESMFIQSLGRTIRENSHDAFNEQHRYVKAYFHITILPSHLNTQSIDEYKCMISANKQEKIKSKELELIDISVDKHCYEPFDDYTKFNAISYYAYRMHNVNYAGIECIRNKQCNEFEDAMVRHIMINNILIHGKYVRCIEGKYKLVDNISIPYYTFNPIVKCTLFDVPFEKLVYDEKISFVERCIQENRIKYMEELLTLFLYYNGVFYHVLRYRHPSKKSYNASVIIPKQKMGPMRMFDGSKWEDVSVNDEQEVLRIYSQELERVQTAIDMHPIKYGIRSVLDNKIRVRGSVQKDRRKTQRGLELYSHSIDKLVDLATDYGLQITVRSKEALINSIAKFLSNNNLLIWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5Y3G5</accession>
    <name>A0AAD5Y3G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_001134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000013">
        <property type="protein sequence ID" value="KAJ3227627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5Y3G5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF87">
        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3227627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="571" mass="63061" checksum="BA73BF85DF1B29A7" modified="2024-05-29" version="1">MTEDTTKTAVTDTIMDDETSLDEVWVLPEKANSFKVFGFNFLKVVAAGIFFQTIILALEGSMFGTVSATLHSLFAVLSLNDLPQIAMMISGVLGPAVVKFAEVYGQFPLAVSGVFFAILTYSLFIVSGNPGHIMNGATETAVLTWHSYCFVAGQMTESVARVFLSTLETILITVYIPIRLRATFTAVVNLPNYLIRLVAPLLATSFYHEWRLIFVVTIPVVLLSFFVMYYPLVKIENQYRKKRQSTSFIQICKDLDLIGALLLICGVCCTLAPPMINYSESITHSKNLIPLVIGIICILLFVPYEYYLAPTPVFHRRLVTNITLVCCLIVNAIIYAASNMAFSNFSALFQITKGVSDDTAAMLQYGYGAGYGAGALICGLLIQYTRKLKIWIWSGYLVYLLGFCLFLNTRGAVTSIAEVVIVQIVAGIGCGISLPAIYICVQAAVEKRDVPMAATLVTFTTYVFGPFCGLFASSIWNRYLPDIIAAKPGGNTLDMFGIVDTILSNWKSDSYNEVQKNIIIESYLETQRLTTFIAIGMLVVGLVPIYFIRVNDLPEEENTKEKKENQVETVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSV2</accession>
    <name>A0AAD5TSV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HK099_002719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001922">
        <property type="protein sequence ID" value="KAJ3200355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSV2"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAJ3200355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="147" mass="15408" checksum="8A9B090123FF3D87" modified="2024-05-29" version="1">MCGGIVGFKCKEGLECKIKKENPTISDQSGTCQKPAGRDVKNNPEQPISQEGEICHEHSRNSHICADGLVCGLLNEIVGDAGSICYKDNSTDTNSTDTTNATTVLTSATSTTSSTSTNSILPQATSAGYLVSGYAGLISFLLLFVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TSZ0</accession>
    <name>A0AAD5TSZ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HK099_003171</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010002111">
        <property type="protein sequence ID" value="KAJ3199448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TSZ0"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000002">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42871">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42871:SF1">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAJ3199448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="241" mass="27154" checksum="62E20803B714D996" modified="2024-05-29" version="1" fragment="single">MLDRLSEINYSPNPVLAKALDVIFILHADHELNCSTAAMRQLASTGIDPYNCLVAAASALYGPSHGGANEAALKMLEEIGSVKNIPYFIAEVKSKKRKLMGFGHRVYKSYDPRAKILKKIADQVFGIMGKNDLIDVAIELERIALSDEYFIKRNLYPNVDFYSGLIYKAIAMGFPTDFFPVLFAIARTSGWLAHWLEQLKNPIPIFRPGQVYEGFSPRQYIPLENREVGEEKLQKKLRPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TTA7</accession>
    <name>A0AAD5TTA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_002075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001663">
        <property type="protein sequence ID" value="KAJ3201843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TTA7"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3201843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="228" mass="25547" checksum="3EC247E541F0F86B" modified="2024-05-29" version="1" fragment="single">MYCGFLVDSRYYKAYCVAHLFLLGNFTQVDDNICPQMASISDAVKFNDTCLDALINYNFMGSYNFQEITPRYYSYLKENNKLYEKGSNEFTARETFTGITPTVLTSTVVSTGTYDMTKTIFETLSSIKTATSFSEKAVNTTIPTTITIPVFSTSTQANGMVVTATSTTVKVTQWPITTTIKVPVTSTYMDYTTREASTEVVKTSHVYTSQFSYTKTIPFSAYNLQTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUF5</accession>
    <name>A0AAD5TUF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001027</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001267">
        <property type="protein sequence ID" value="KAJ3204766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUF5"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="186" mass="21636" checksum="3E1F70B32ADBE31B" modified="2024-05-29" version="1">MKNEQVKFENNDGTKSVAAAMTKHELQNDDELTILGQCEIKKKNEFRKNDEIKQTYQIDFISTDDTEVCRTEAVDFTRLHTRFYTNICKYPVIYPDEKKKNFWLAWYTKDLRTCYKNSLRNFLRMDSFNLAKVPGAPTDAYPLPSIRKSVERLGKATIFTALDATSGFDQLQSSKKDQEKTAFSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUH8</accession>
    <name>A0AAD5TUH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_000899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001228">
        <property type="protein sequence ID" value="KAJ3205161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUH8"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051499">
        <property type="entry name" value="Phosducin-like_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46052:SF1">
        <property type="entry name" value="PHOSDUCIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3205161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="216" mass="25290" checksum="DE9B4A01CED3AE67" modified="2024-05-29" version="1" fragment="single">WLQREIEREEKEFKKSDDEEGAEEDVDELIRELEKEEEEKFENLSLMSRESKLSHLMELSSSYSKNKLKKKKFGNLKFVSSLEFLTEIENEIPTQKIIINLFQKNIIKTKKINDQFNYLANKYVHLKFLSLNNNELDNDANQSALLKDNDKFLINEIGLPCILVYVAGELTLNLTRIDLLLEKSGSNDYDKNLEALEDFLIDLQVLNEADIDENFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUK3</accession>
    <name>A0AAD5TUK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_001224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001322">
        <property type="protein sequence ID" value="KAJ3204240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUK3"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3204240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="116" mass="13640" checksum="5A1174FA003259A8" modified="2024-05-29" version="1" fragment="single">KGIQFRKIVHINNEIFIKTHQYGSTIVTSTKSHLDIKEFFVFKLVENLNIGSESHWYCHNDIKDSIYIATKGMSFNKTTVEKELVRLRKPSLLSKNFVFKNDFITNFNTFLNLTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TUV6</accession>
    <name>A0AAD5TUV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_002555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001856">
        <property type="protein sequence ID" value="KAJ3200671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TUV6"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3200671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="118" mass="13811" checksum="57CE156CF02D1498" modified="2024-05-29" version="1" fragment="single">MLQLSTITQGNFKNSSSEMINKNPKQNSVDNVYQKQQKTLKFLQTLKSGDYEDAKNLLQLFERQKLKKFSEKKNNFAIKIQEKEKSISSSKNNKEELNLIMFELLDLLSELEFDESIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TV39</accession>
    <name>A0AAD5TV39_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HK099_008684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000985">
        <property type="protein sequence ID" value="KAJ3208622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TV39"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="65"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAJ3208622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="488" mass="56718" checksum="908FBB5B251B4D38" modified="2024-05-29" version="1">MENELELFLIEIVQYFDLQKRKSVGLRKMATKANFLLEQVIYNTKPLPILSNSNQNEVCKVNLKNYNVNKLPNEILNLIFERFKVKDETSNFPLLNLALVNKKWSTVALPLLYRDLYTRHDSVSKLYTLAKCLKLNSIYRESHTNWFNPFISSLTFYSTSKTRSDLNQDICKKLLKIIASYAKHLMSFILIIEQMSGYDVLNFNLNDLNDLFTSCQYITHLDINKLTNTWDIKPIEKGSNLKNSFLKLKTLCIMSMEGGNDEYASLFSNFPPTSIEVLEIPDLTMETAESLKDCLKNLYSLTLTGNLYNEPGEFKENVANLVFQKATNLKKLNSYFHLSEAMFNIMIKCKVSLKYLKCTIFGKQVDPLSYCSWETGLKVYFKSLGNHLTELYLTLIESKENELDDSKLDFFSNHLKNLEIFSYKVYKNINEDYQEVSPFANVSESAVTKFCFSMKKLKRVAFRNKIKPTRTDLKEVFKSYGIRLVDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TVG1</accession>
    <name>A0AAD5TVG1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleolar protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NOP16</name>
        <name evidence="7" type="ORF">HK099_001765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NOP16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010001532">
        <property type="protein sequence ID" value="KAJ3202702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TVG1"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019002">
        <property type="entry name" value="Ribosome_biogenesis_Nop16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243">
        <property type="entry name" value="HSPC111 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09420">
        <property type="entry name" value="Nop16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAJ3202702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="230" mass="26291" checksum="552BE757CAF92E0F" modified="2024-05-29" version="1">MGKSRSAHKKSNTKTSRRQKNRKNVSFSQAHPLVKENWDKKLTVKQNYEKLGLTTSLNGKAGGVELTVEQLELIKKNNNDNETNNLSKLAIKKGAVGLRTLEGNEEVLKEVEEGEDVHSEFIEDNVVVDVRGLGVGKRIGQKKNNVEVKESNTPIIDKMIIESQSEVKRKRHVSEQELKFLVDLKKKYNSDYFKMSRDRKLNPFLINESSLKKKFKLLEEDISDGLIKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW08</accession>
    <name>A0AAD5TW08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HK099_008550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000950">
        <property type="protein sequence ID" value="KAJ3209258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW08"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="147"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAJ3209258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="589" mass="66195" checksum="BEA7DAB8D04EBBEC" modified="2024-05-29" version="1">MTSNNDFFNCSSSSSKRALQKHVSSNDQSLSFTKLNIDANPIEPKFSQLINVDPPKQFSSLPNTDHLIFKSSPTQSSFPQNITTQSCPQVPILKKKASISRPTSLMKDFSNTFNTPTSSYFSQTYYDNFQDSIDNSEFSPGDEIGPYVLQKKIGTGAFGTVYKARKESLPNSPNSTSPTVAVKVINRNSRCNSISSSLSHSLQSNFIPENNNNNINPDNDIDELVSQETDIWKQLSHPNILSLHDVVQAEGNIFVISEIAKGGSLLQYIQNNPGGISEKDAARLFRELIYAVKYMHDLGIVHRDIKAENILLVDKFDEIEHSFTKNVQLNSTTAHHHHHKKQSDFHLNTLDQLFISPTSSTPPLTPQSIRSANSNSIPIWMPEGKVLFKGNNENNISSLTNDTSNNNIEVNSSKEIFSSTASLPFQFEQCNEFFHNNDHTKDSDTDYTPTQSNADLTQCTKDINSYVCKLADFGLSGYIHEKEKDRTVVGSIHYCSPEEIKQQSFGQPSSDIWSLGVVLFAMVTGTLPFNDDYIPRLQQQIINGRYDKSKLEKFSKNFQDLISSLLQVQKEKRITMAQLLQHPWVLENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TW65</accession>
    <name>A0AAD5TW65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HK099_008256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">JEL0476</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JADGJW010000892">
        <property type="protein sequence ID" value="KAJ3210418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0AAD5TW65"/>
    <dbReference type="Proteomes" id="UP001211065">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAJ3210418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP001211065"/>
        </source>
    </evidence>
    <sequence length="355" mass="41368" checksum="5A6E1CCF309247EA" modified="2024-05-29" version="1" fragment="single">PTFTGGLKFLKKLEKESRPLKLSDESYNNPHQGVSTKFNNLKVGLVAKINANNVKGSFLRTLVYEMKTKEEADLFLPILALWNEKASIFHPYHDGAVILEALFAIKGTEDLLLNILSDRFKYRIYPTREHLNILMTKLQKIHFKKKDEESLNNLYKLFCISIYHDILPTSTTYSKLISTGIFGETEDGKNKSLKTLQELKSFNLKLNFESSLAFSYLKFKQDDLNECLNILIKNNKNLNDSRFFKLFFILNFKLKNFDECFNNLKALFEFENLNNSKKFKNLTKNFNKEELNFFKFFPMIKKFDSILIEFLENLKSSDQKDLLALFLKTKAILVHSTENAGFAESEKIKEYLKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2024-05-29" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0AAD5TWB4</accession>
    <name>A0AAD5TWB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha-1,3/1,6-mannosyltransferase ALG2</fullName>
            <ecNumber evidence="4">2.4.1.132</ecNumber>
            <ecNumber evidence="4">2.4.1.257</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ALG2</name>
        <name evidence="6" type="ORF">HK099_007921</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Clydaea vesicula</name>
        <dbReference type="NCBI Taxonomy" id="447962"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Chytridiomycota</taxon>
            <taxon>Chytridiomycota incertae sedis</taxon>
            <taxon>Chytridiomycetes</taxon>
            <taxon>Lobulomycetales</taxon>
            <taxon>Lobulomycetaceae</taxon>
            <taxon>Clydaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-05" db="EMBL/GenBank/DDBJ databases">
            <title>Phylogenomic resolution of chytrid fungi.</title>
            <authorList>
                <person name="Stajich J.E."/>
                <person name="Amses K."/>
                <person name="Simmons R."/>
                <person name="Seto K."/>
                <person name="Myers J."/>
                <person name="Bonds A."/>
                <person name="Quandt C.A."/>
                <person name="Barry K."/>
                <person name="Liu P."/>
                <person name="Grigoriev I."/>
                <person name="Longcore J.E."/>
                <person name="James T.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">JEL0476</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19511"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58472"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="EC" id="2.4.1.132"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:29516"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29519"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" i
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